{"text_format":"3","workbook":"xlsx","n_sheets":1,"sheets":["Proteins"],"not_rendered":{"defined_names":1},"read":"whole","date_system":"1900"}

{"sheet":"Proteins","index":0,"n_rows":9109,"n_cols":74,"rows_kept":1125,"cut":true,"bounds":{"rows_first":500,"rows_last":125,"rows_between":500,"halvings":2}}
["Checked","Protein FDR Confidence: Combined","Master","Accession","Description","Exp. q-value: Combined","Sum PEP Score","Coverage [%]","# Peptides","# PSMs","# Unique Peptides","# AAs","MW [kDa]","calc. pI","Score Sequest HT: Sequest HT","# Peptides (by Search Engine): Sequest HT","Biological Process","Cellular Component","Molecular Function","Pfam IDs","Entrez Gene ID","Ensembl Gene ID","Gene Symbol","Chromosome","KEGG Pathways","Reactome Pathways","WikiPathways","# Protein Pathway Groups","# Razor Peptides","Abundance Ratio: (KO) / (WT)","Abundance Ratio (log2): (KO) / (WT)","Abundance Ratio P-Value: (KO) / (WT)","Abundance Ratio Adj. P-Value: (KO) / (WT)","Abundances (Grouped): empty","Abundances (Grouped): KO","Abundances (Grouped): WT","Abundances (Grouped) CV [%]: empty","Abundances (Grouped) CV [%]: KO","Abundances (Grouped) CV [%]: WT","Abundances (Normalized): F5: 129C, Sample, empty","Abundances (Normalized): F5: 130C, Sample, empty","Abundances (Normalized): F5: 131C, Sample, empty","Abundances (Normalized): F5: 126, Sample, KO","Abundances (Normalized): F5: 127C, Sample, KO","Abundances (Normalized): F5: 128C, Sample, KO","Abundances (Normalized): F5: 130N, Sample, KO","Abundances (Normalized): F5: 127N, Sample, WT","Abundances (Normalized): F5: 128N, Sample, WT","Abundances (Normalized): F5: 129N, Sample, WT","Abundances (Normalized): F5: 131N, Sample, WT","Abundance: F5: 129C, Sample, empty","Abundance: F5: 130C, Sample, empty","Abundance: F5: 131C, Sample, empty","Abundance: F5: 126, Sample, KO","Abundance: F5: 127C, Sample, KO","Abundance: F5: 128C, Sample, KO","Abundance: F5: 130N, Sample, KO","Abundance: F5: 127N, Sample, WT","Abundance: F5: 128N, Sample, WT","Abundance: F5: 129N, Sample, WT","Abundance: F5: 131N, Sample, WT","Found in Sample: [S51] F5: 129C, Sample, empty","Found in Sample: [S53] F5: 130C, Sample, empty","Found in Sample: [S55] F5: 131C, Sample, empty","Found in Sample: [S45] F5: 126, Sample, KO","Found in Sample: [S47] F5: 127C, Sample, KO","Found in Sample: [S49] F5: 128C, Sample, KO","Found in Sample: [S52] F5: 130N, Sample, KO","Found in Sample: [S46] F5: 127N, Sample, WT","Found in Sample: [S48] F5: 128N, Sample, WT","Found in Sample: [S50] F5: 129N, Sample, WT","Found in Sample: [S54] F5: 131N, Sample, WT","# Protein Groups","Modifications"]
[false,"High","Master Protein","P56199","Integrin alpha-1 OS=Homo sapiens OX=9606 GN=ITGA1 PE=1 SV=2",0,51.285,10,12,13,12,1179,130.8,6.29,43.26,12,"cell organization and biogenesis;cellular component movement;regulation of biological process;response to stimulus","cell surface;membrane","metal ion binding;protein binding","Pf00092, Pf01839, Pf08441, Pf13517, Pf13519, Pf14312","3672","ENSG00000213949.8","ITGA1","5","Regulation of actin cytoskeleton; PI3K-Akt signaling pathway; Hematopoietic cell lineage; Arrhythmogenic right ventricular cardiomyopathy (ARVC); Hypertrophic cardiomyopathy (HCM); ECM-receptor interaction; Focal adhesion; Dilated cardiomyopathy","CHL1 interactions; Other semaphorin interactions; Integrin cell surface interactions; Smooth Muscle Contraction; Laminin interactions; Platelet Adhesion to exposed collagen","Integrin-mediated Cell Adhesion; Arrhythmogenic Right Ventricular Cardiomyopathy; miRNA targets in ECM and membrane receptors; Signaling of Hepatocyte Growth Factor Receptor; NOTCH1 regulation of human endothelial cell calcification; Regulation of Actin Cytoskeleton",27,0,0.445,-1.17,1e-17,5.72363636363636E-15,67.1,71.7,161.2,"",13.4,10.98,808.1,"","",855.9,839.1,871.9,1099.9,1775.1,2087.9,1805.5,2218.5,41,"","",683,635.1,692.4,796.6,1278.5,2087.9,1471.5,1770.3,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P05187","Alkaline phosphatase, placental type OS=Homo sapiens OX=9606 GN=ALPP PE=1 SV=2",0,43.412,17,7,12,7,535,57.9,6.29,38.96,7,"metabolic process","cell surface;membrane","catalytic activity;metal ion binding;protein binding","Pf00245","250","ENSG00000163283.6","ALPP","2","Metabolic pathways; Folate biosynthesis; Thiamine metabolism","Intra-Golgi traffic","",7,0,0.483,-1.05,1e-17,5.72363636363636E-15,64.5,76.7,158.8,"",20.03,9.53,421.8,"","",431.8,551.5,455.2,662.8,922.8,1067.3,1008.6,1158.2,21.4,"","",344.6,417.4,361.5,480,664.6,1067.3,822,924.2,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P32456","Guanylate-binding protein 2 OS=Homo sapiens OX=9606 GN=GBP2 PE=1 SV=3",0,38.341,16,9,12,8,591,67.2,5.71,33.35,9,"regulation of biological process;response to stimulus","cytoplasm;cytoskeleton;cytosol;Golgi;membrane","catalytic activity;nucleotide binding;protein binding","Pf02263, Pf02841, Pf05879","2634","ENSG00000162645.12","GBP2","1","NOD-like receptor signaling pathway","Interferon alpha/beta signaling; Interferon gamma signaling","",6,0,2.046,1.03,1e-17,5.72363636363636E-15,114.3,124.7,60.9,"",1.44,16.13,938.2,"","",1049.1,1016.5,1019.1,1027.8,455.3,518.1,482.8,647,47.6,"","",837.2,769.4,809.3,744.4,327.9,518.1,393.5,516.3,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q99541","Perilipin-2 OS=Homo sapiens OX=9606 GN=PLIN2 PE=1 SV=2",0,27.352,17,6,7,6,437,48,6.8,21.04,6,"regulation of biological process;response to stimulus;transport","cytoplasm;cytosol;endoplasmic reticulum;extracellular;membrane;nucleus","","Pf03036","123","ENSG00000147872.9","PLIN2","9","PPAR signaling pathway","PPARA activates gene expression","Adipogenesis",6,0,2.297,1.2,1e-17,5.72363636363636E-15,130.4,118.1,51.4,"",22.58,12.86,1206.2,"","",1263.8,975,1224,752.8,538.9,521.4,434,416.4,61.2,"","",1008.5,738,972,545.2,388.1,521.4,353.7,332.3,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P48594","Serpin B4 OS=Homo sapiens OX=9606 GN=SERPINB4 PE=1 SV=2",0,19.891,16,5,5,2,390,44.8,6.21,15.11,5,"regulation of biological process","cytoplasm","enzyme regulator activity;protein binding","Pf00079","6318","ENSG00000206073.10","SERPINB4","18","Amoebiasis","","",1,0,2.639,1.4,1e-17,5.72363636363636E-15,106.1,140.6,53.3,"",16.42,14,155.7,"","",201,211.9,217.1,147.6,68,81.6,94.2,74.9,7.9,"","",160.4,160.4,172.4,106.9,49,81.6,76.8,59.8,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P29508","Serpin B3 OS=Homo sapiens OX=9606 GN=SERPINB3 PE=1 SV=2",0,12.558,11,5,5,2,390,44.5,6.81,10.61,5,"cell communication;regulation of biological process;transport","cytoplasm;extracellular;nucleus;organelle lumen","enzyme regulator activity;protein binding;receptor activity","Pf00079","6317","ENSG00000057149.15","SERPINB3","18","Amoebiasis","Neutrophil degranulation","",4,1,3.094,1.63,1e-17,5.72363636363636E-15,127.9,130.1,42,"",12.19,18.74,737.1,"","",823.3,718.9,782.3,617.5,233.5,306.8,251.5,195.6,37.4,"","",657,544.1,621.2,447.2,168.2,306.8,205,156.1,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q01995","Transgelin OS=Homo sapiens OX=9606 GN=TAGLN PE=1 SV=4",0,11.498,17,3,3,3,201,22.6,8.84,9.58,3,"cell differentiation","cytoplasm","protein binding","Pf00307, Pf00402","6876","ENSG00000149591.16","TAGLN","11","","","",0,0,0.371,-1.43,1e-17,5.72363636363636E-15,"",81.2,218.8,"",37.75,25.62,"","","",26.4,25.5,29.1,51.9,77.8,68.8,71.8,114.8,"","","",21.1,19.3,23.1,37.6,56,68.8,58.5,91.6,"Not Found","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P98168","Zinc finger X-linked protein ZXDA OS=Homo sapiens OX=9606 GN=ZXDA PE=1 SV=2",0,11.423,5,3,4,3,799,84.7,7.52,12.82,3,"metabolic process;regulation of biological process","nucleus","metal ion binding;protein binding","Pf13465","7789","ENSG00000198205.6","ZXDA","X","","","",0,0,0.426,-1.23,1e-17,5.72363636363636E-15,"",89.7,210.3,"",1.5,3.99,"","","",107.9,105.2,104.1,105.5,255.3,246.1,248.1,232,"","","",86.1,79.6,82.7,76.4,183.9,246.1,202.2,185.1,"Not Found","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q9Y244","Proteasome maturation protein OS=Homo sapiens OX=9606 GN=POMP PE=1 SV=1",0,9.988,17,2,3,2,141,15.8,5.11,11.42,2,"cell organization and biogenesis","cytoplasm;cytosol;endoplasmic reticulum;membrane;nucleus","protein binding","Pf05348","51371","ENSG00000132963.7","POMP","13","Proteasome","","",1,0,0.44,-1.18,1e-17,5.72363636363636E-15,82.2,66.5,151.2,"",6.9,1.61,258.2,"","",202.8,201.1,215.1,232.9,462.5,477.8,479.3,471.8,13.1,"","",161.8,152.2,170.8,168.7,333.1,477.8,390.6,376.5,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q92626","Peroxidasin homolog OS=Homo sapiens OX=9606 GN=PXDN PE=1 SV=2",0,8.978,1,1,1,1,1479,165.2,7.17,4.78,1,"cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus","endoplasmic reticulum;extracellular","antioxidant activity;catalytic activity;metal ion binding;protein binding;structural molecule activity","Pf00047, Pf00093, Pf03098, Pf05825, Pf07679, Pf07686, Pf08205, Pf12799, Pf13855, Pf13895, Pf13927","7837","ENSG00000130508.10","PXDN","2","","Crosslinking of collagen fibrils","EGF/EGFR Signaling Pathway",5,0,0.299,-1.74,1e-17,5.72363636363636E-15,"",69.1,230.9,"",3.61,12.11,"","","",12.4,12.3,13,13.3,52.1,40,42.6,42.2,"","","",9.9,9.3,10.3,9.6,37.5,40,34.7,33.7,"Not Found","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","O94875","Sorbin and SH3 domain-containing protein 2 OS=Homo sapiens OX=9606 GN=SORBS2 PE=1 SV=3",0,8.251,2,1,1,1,1100,124,8.31,4.23,1,"cell growth;cell organization and biogenesis;cellular component movement","cytoplasm;cytoskeleton;membrane;nucleus","protein binding;RNA binding;structural molecule activity","Pf00018, Pf02208, Pf07653, Pf14604","8470","ENSG00000154556.17","SORBS2","4","","","",0,0,0.19,-2.39,1e-17,5.72363636363636E-15,91.7,33.3,175,"",31.06,11.72,45.3,"","",13.3,18.1,15,26,97.6,89.2,73.5,84,2.3,"","",10.6,13.7,11.9,18.8,70.3,89.2,59.9,67,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q9Y6U3","Adseverin OS=Homo sapiens OX=9606 GN=SCIN PE=1 SV=4",0,8.212,5,4,4,4,715,80.4,5.71,8.58,4,"cell organization and biogenesis;regulation of biological process;transport","cytoplasm;cytoskeleton","metal ion binding;protein binding","Pf00626","85477","ENSG00000006747.14","SCIN","7","Regulation of actin cytoskeleton; Fc gamma R-mediated phagocytosis; Viral carcinogenesis","","Endochondral Ossification",4,0,0.294,-1.77,1e-17,5.72363636363636E-15,"",68.2,231.8,"",16.09,5.6,"","","",27.6,28.9,28.3,38.1,93,99.5,95.2,105.5,"","","",22,21.9,22.5,27.6,67,99.5,77.6,84.2,"Not Found","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P32754","4-hydroxyphenylpyruvate dioxygenase OS=Homo sapiens OX=9606 GN=HPD PE=1 SV=2",0,5.851,6,3,3,3,393,44.9,7.01,7.44,3,"metabolic process","cytosol;membrane","catalytic activity;metal ion binding","Pf00903, Pf12681, Pf13669","3242","","HPD","12","Metabolic pathways; Phenylalanine metabolism; Ubiquinone and other terpenoid-quinone biosynthesis; Tyrosine metabolism","Phenylalanine and tyrosine catabolism","",8,0,0.221,-2.17,1e-17,5.72363636363636E-15,67,42.2,190.7,"",8.56,9.96,55.2,"","",34.2,39.5,32.4,35.3,168.6,146.3,172.8,141.5,2.8,"","",27.3,29.9,25.7,25.6,121.4,146.3,140.8,112.9,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q16143","Beta-synuclein OS=Homo sapiens OX=9606 GN=SNCB PE=1 SV=1",0.003,3.446,7,1,1,1,134,14.3,4.41,2.16,1,"cell communication;cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus","cytoplasm;cytosol;mitochondrion","enzyme regulator activity;metal ion binding","Pf01387","6620","ENSG00000074317.10","SNCB","5","","MTF1 activates gene expression","",3,0,0.376,-1.41,1e-17,5.72363636363636E-15,92.2,56.8,151,"",11.11,3.86,61.1,"","",34.2,41.9,34.4,41.3,99.6,106.9,100.6,98,3.1,"","",27.3,31.7,27.3,29.9,71.7,106.9,82,78.2,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q9NR64","Kelch-like protein 1 OS=Homo sapiens OX=9606 GN=KLHL1 PE=2 SV=1",0,38.244,13,10,10,8,748,82.6,6.39,26.45,10,"cell organization and biogenesis;metabolic process;response to stimulus","cytoplasm;cytoskeleton","catalytic activity;protein binding","Pf00651, Pf01344, Pf07646, Pf07707, Pf13415, Pf13418, Pf13964","57626","ENSG00000150361.11","KLHL1","13","","","",0,1,1.877,0.91,4.44089209850063e-16,2.46704617519058E-13,121.1,116.7,62.2,"",11.02,1.55,1080.1,"","",1090.1,1159.5,994.7,897.5,557.3,552,562.2,542.1,54.8,"","",869.9,877.6,789.9,650,401.4,552,458.2,432.6,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P05091","Aldehyde dehydrogenase, mitochondrial OS=Homo sapiens OX=9606 GN=ALDH2 PE=1 SV=2",0,27.698,16,8,9,6,517,56.3,7.05,26.58,8,"metabolic process","mitochondrion;organelle lumen","catalytic activity;nucleotide binding","Pf00171","217","ENSG00000111275.12","ALDH2","12","Ascorbate and aldarate metabolism; Pentose and glucuronate interconversions; beta-Alanine metabolism; Arginine and proline metabolism; Glycerolipid metabolism; Lysine degradation; Metabolic pathways; Fatty acid degradation; Glycolysis / Gluconeogenesis; Pyruvate metabolism; Valine, leucine and isoleucine degradation; Histidine metabolism; Tryptophan metabolism","Ethanol oxidation; Metabolism of serotonin","Fatty Acid Omega Oxidation; Tryptophan metabolism",24,1,0.545,-0.87,1.77635683940025e-15,9.58623656645484e-13,86.9,75.2,137.9,"",3.82,7.73,601.2,"","",509.5,531.8,502.8,546.1,874.6,998.2,912.6,1033.9,30.5,"","",406.6,402.5,399.3,395.5,629.9,998.2,743.8,825,"High","High","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"Medium","Master Protein","Q9NUU6","Inactive ubiquitin thioesterase OTULINL OS=Homo sapiens OX=9606 GN=OTULINL PE=1 SV=1",0.046,1.497,2,1,1,1,356,42.2,9.29,2.42,1,"","","","","54491","ENSG00000145569.5","FAM105A","5","","","",0,0,0.436,-1.2,2.88657986402541e-15,1.51449223532533e-12,107.9,58.3,133.8,"",9.13,2.59,147.8,"","",79.6,67.6,80.2,84.1,180.1,191.3,183.7,183.1,7.5,"","",63.5,51.2,63.7,60.9,129.7,191.3,149.7,146.1,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P27105","Erythrocyte band 7 integral membrane protein OS=Homo sapiens OX=9606 GN=STOM PE=1 SV=3",0,72.296,44,11,28,11,288,31.7,7.88,72.38,11,"cell organization and biogenesis;regulation of biological process;transport","cytoplasm;cytoskeleton;cytosol;endoplasmic reticulum;membrane;mitochondrion","protein binding","Pf01145","2040","ENSG00000148175.12","STOM","9","","Neutrophil degranulation; Stimuli-sensing channels","",6,0,0.594,-0.75,5.55111512312578e-15,2.83376925528648e-12,78.7,82.5,138.9,"",17.34,5.17,2775.1,"","",2652,2885.6,2932.8,3864,5160.3,4660.4,4716.6,5086.2,140.8,"","",2116.3,2184.1,2328.9,2798.5,3716.6,4660.4,3844.1,4058.7,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q92604","Acyl-CoA:lysophosphatidylglycerol acyltransferase 1 OS=Homo sapiens OX=9606 GN=LPGAT1 PE=1 SV=1",0,10.341,7,2,2,2,370,43.1,8.92,8.61,2,"metabolic process;regulation of biological process","cytoplasm;endoplasmic reticulum;membrane","catalytic activity","Pf01553","9926","ENSG00000123684.12","LPGAT1","1","Glycerophospholipid metabolism","Acyl chain remodelling of PG","",6,0,0.472,-1.08,1.26565424807268E-14,6.29096774673599e-12,128.9,54.9,116.2,"",55.78,27.17,297.6,"","",132.3,121.2,309.5,112.3,306.3,403.2,235,233.6,15.1,"","",105.6,91.7,245.8,81.3,220.6,403.2,191.5,186.4,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q8IVI9","Nostrin OS=Homo sapiens OX=9606 GN=NOSTRIN PE=1 SV=2",0,7.511,6,3,3,3,506,57.6,8.97,6.72,3,"regulation of biological process;response to stimulus;transport","cytoplasm;cytoskeleton;membrane;nucleus","DNA binding;protein binding","Pf00018, Pf07653, Pf14604","115677","ENSG00000163072.15","NOSTRIN","2","","NOSTRIN mediated eNOS trafficking","",4,0,0.41,-1.29,1.46549439250521e-14,6.5905376394377e-12,"",87.3,212.7,"",24.85,9.05,"","","",34.6,25.1,30.1,44.7,78.3,81.1,65.9,78.9,"","","",27.6,19,23.9,32.4,56.4,81.1,53.7,63,"Not Found","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q6DKJ4","Nucleoredoxin OS=Homo sapiens OX=9606 GN=NXN PE=1 SV=2",0,15.85,8,2,2,2,435,48.4,4.97,9.05,2,"cell differentiation;cellular homeostasis;development;metabolic process;regulation of biological process;response to stimulus","cytoplasm;cytosol;nucleus","antioxidant activity;catalytic activity","Pf00085, Pf00578, Pf13098, Pf13899, Pf13905, Pf14595","64359","ENSG00000167693.16","NXN","17","","","",0,0,0.402,-1.31,3.99680288865056e-14,1.75561890606586e-11,104.6,56,139.4,"",15.74,10.15,51.2,"","",27.7,27.2,20.7,30.5,61.4,76.7,72.1,64.7,2.6,"","",22.1,20.6,16.4,22.1,44.2,76.7,58.8,51.6,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P08648","Integrin alpha-5 OS=Homo sapiens OX=9606 GN=ITGA5 PE=1 SV=2",0,71.181,16,16,19,16,1049,114.5,5.77,56.76,16,"cell differentiation;cell organization and biogenesis;cellular component movement;regulation of biological process;response to stimulus","cell surface;cytoplasm;endoplasmic reticulum;Golgi;membrane","metal ion binding;protein binding;receptor activity","Pf01839, Pf08441","3678","ENSG00000161638.10","ITGA5","12","PI3K-Akt signaling pathway; Focal adhesion; Hematopoietic cell lineage; Shigellosis; Bacterial invasion of epithelial cells; Pertussis; Arrhythmogenic right ventricular cardiomyopathy (ARVC); Proteoglycans in cancer; Phagosome; Hypertrophic cardiomyopathy (HCM); MicroRNAs in cancer; ECM-receptor interaction; Dilated cardiomyopathy; Regulation of actin cytoskeleton","RUNX2 regulates genes involved in cell migration; Integrin cell surface interactions; Signal transduction by L1; Elastic fibre formation; Fibronectin matrix formation; Cell surface interactions at the vascular wall","Integrin-mediated Cell Adhesion; Arrhythmogenic Right Ventricular Cardiomyopathy; Focal Adhesion; Focal Adhesion-PI3K-Akt-mTOR-signaling pathway",33,0,1.669,0.74,7.93809462606987e-13,3.05989247545322E-10,109.5,119.1,71.4,"",13.05,4.56,2970.3,"","",3340.6,3127.9,3384.1,2509.2,1787.4,1959.4,1982.5,1915,150.7,"","",2665.8,2367.5,2687.3,1817.3,1287.3,1959.4,1615.8,1528.1,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","O15231-3","Isoform 3 of Zinc finger protein 185 OS=Homo sapiens OX=9606 GN=ZNF185",0,117.843,44,23,27,23,690,73.6,7.01,93.85,23,"","cytoplasm;cytoskeleton","metal ion binding;protein binding","Pf00412","7739","ENSG00000147394.18","ZNF185","X","","","",0,0,0.608,-0.72,1.43063338953198e-12,5.15160358816047e-10,86.2,80.8,133,"",18.48,9.57,1429,"","",1285,1398.7,1284.6,1849.4,2214.4,2196.3,2144.9,2620.4,72.5,"","",1025.4,1058.7,1020.1,1339.4,1594.9,2196.3,1748.1,2091,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q16654","[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial OS=Homo sapiens OX=9606 GN=PDK4 PE=1 SV=1",0,18.773,13,5,6,5,411,46.4,6.65,18.34,5,"cell communication;metabolic process;regulation of biological process;response to stimulus","membrane;mitochondrion;organelle lumen","catalytic activity;nucleotide binding","Pf02518, Pf10436","5166","ENSG00000004799.7","PDK4","7","","Regulation of pyruvate dehydrogenase (PDH) complex; Signaling by Retinoic Acid","Estrogen Receptor Pathway; Amino Acid metabolism",10,0,1.9,0.93,1.62847513252018E-12,5.59247969146203e-10,119.2,118.5,62.4,"",25.13,12.43,364.6,"","",387.1,339.5,464.8,248.5,222.7,202.9,179.5,169.1,18.5,"","",308.9,257,369.1,180,160.4,202.9,146.3,134.9,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P51649","Succinate-semialdehyde dehydrogenase, mitochondrial OS=Homo sapiens OX=9606 GN=ALDH5A1 PE=1 SV=2",0,91.219,29,14,22,14,535,57.2,8.28,84.87,14,"cell organization and biogenesis;metabolic process","mitochondrion;organelle lumen","catalytic activity;nucleotide binding;protein binding","Pf00171","7915","ENSG00000112294.12","ALDH5A1","6","Metabolic pathways; Alanine, aspartate and glutamate metabolism; Butanoate metabolism","Degradation of GABA","",8,0,0.625,-0.68,2.35078623234131e-12,7.78976322043203e-10,142.5,60.6,96.9,94.89,2.94,3.8,2465.7,12520.9,"",2361.1,2358.4,2359.9,2500.8,3855.9,3830.4,3725,3543.1,125.1,3.5,"",1884.2,1785.1,1874,1811.2,2777.1,3830.4,3035.9,2827.3,"High","High","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q96QD5","DEP domain-containing protein 7 OS=Homo sapiens OX=9606 GN=DEPDC7 PE=2 SV=1",0,39.54,27,13,13,13,511,58.3,7.77,34.04,13,"regulation of biological process;response to stimulus","cytosol","enzyme regulator activity","Pf00610","91614","ENSG00000121690.10","DEPDC7","11","","Rho GTPase cycle","",3,0,0.654,-0.61,6.45894449036177e-11,1.9676861860315E-8,89.2,83.4,127.4,"",7.21,4.18,2406.6,"","",2200.2,2299,2069,2454.3,3664.3,3384.1,3493.8,3337.8,122.1,"","",1755.8,1740.1,1643,1777.5,2639.1,3384.1,2847.5,2663.5,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","O14786","Neuropilin-1 OS=Homo sapiens OX=9606 GN=NRP1 PE=1 SV=3",0,25.489,10,7,7,7,923,103.1,5.88,21.03,7,"cell communication;cell differentiation;cell growth;cell organization and biogenesis;cellular component movement;development;regulation of biological process;response to stimulus;transport","cell surface;cytosol;endosome;extracellular;membrane","catalytic activity;enzyme regulator activity;metal ion binding;protein binding;receptor activity;signal transducer activity","Pf00431, Pf00629, Pf00754, Pf11980","8829","ENSG00000099250.17","NRP1","10","Axon guidance; HTLV-I infection","CHL1 interactions; SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion; Sema3A PAK dependent Axon repulsion; Signal transduction by L1; Signaling by ROBO receptors; CRMPs in Sema3A signaling; Neurophilin interactions with VEGF and VEGFR","",16,0,1.796,0.84,9.79099024078778e-11,2.93543212171428e-08,100.8,128,71.3,"",3.21,5.04,404.1,"","",500.9,526,528.1,496.7,304.2,285.7,285.9,268.9,20.5,"","",399.7,398.1,419.4,359.7,219.1,285.7,233,214.6,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q6ZMZ3","Nesprin-3 OS=Homo sapiens OX=9606 GN=SYNE3 PE=1 SV=2",0.006,2.729,1,1,1,1,975,112.1,6.23,3.01,1,"cell organization and biogenesis;regulation of biological process","endoplasmic reticulum;membrane;nucleus","protein binding","Pf10541","161176","ENSG00000176438.12","SYNE3","14","","","",0,0,0.425,-1.23,2.43709052938357e-10,6.48334731253476e-08,"",89.5,210.5,"",19.32,17.27,"","","",11.5,13.1,13,17.7,36.2,24.2,33,28.4,"","","",9.2,9.9,10.3,12.8,26.1,24.2,26.9,22.7,"Not Found","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q9H9B1","Histone-lysine N-methyltransferase EHMT1 OS=Homo sapiens OX=9606 GN=EHMT1 PE=1 SV=4",0,125.277,21,24,34,23,1298,141.4,5.76,102.99,24,"cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus","chromosome;nucleus","catalytic activity;metal ion binding;protein binding","Pf00023, Pf00856, Pf05033, Pf12796, Pf13606, Pf13637, Pf13857","79813","ENSG00000181090.19","EHMT1","9","Lysine degradation; Longevity regulating pathway","PKMTs methylate histone lysines; Regulation of TP53 Activity through Methylation; Senescence-Associated Secretory Phenotype (SASP); Transcriptional Regulation by E2F6","Histone Modifications",17,0,0.628,-0.67,3.17563975116286e-10,8.21664159177591e-08,73.6,87.3,139,"",2.52,2.4,1350.1,"","",1594.7,1602.1,1601.2,1680.7,2602.6,2564,2458.5,2534.7,68.5,"","",1272.6,1212.6,1271.5,1217.2,1874.5,2564,2003.7,2022.6,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q9NVX7","Kelch repeat and BTB domain-containing protein 4 OS=Homo sapiens OX=9606 GN=KBTBD4 PE=1 SV=3",0,20.257,15,6,6,6,518,58.1,5.67,17.25,6,"metabolic process;regulation of biological process","cytoplasm;nucleus","protein binding","Pf00651, Pf07646, Pf07707, Pf13415","55709","ENSG00000123444.13","KBTBD4","11","","","",0,0,0.547,-0.87,8.61819948738685e-10,2.08693015279183e-07,98.6,71.2,130.2,"",15.35,12.35,185.3,"","",122.6,117.1,162.2,146.2,267.8,271.6,223.7,212.7,9.4,"","",97.8,88.6,128.8,105.9,192.9,271.6,182.3,169.7,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","O60575","Serine protease inhibitor Kazal-type 4 OS=Homo sapiens OX=9606 GN=SPINK4 PE=3 SV=1",0,6.303,10,2,3,2,86,9.4,7.65,5.74,2,"regulation of biological process;response to stimulus","extracellular","enzyme regulator activity;protein binding","Pf00050, Pf07648","27290","ENSG00000122711.8","SPINK4","9","","","",0,0,1.809,0.86,8.42584224614029e-10,2.08693015279183e-07,111.5,121.4,67.1,"",5.98,6.99,232.6,"","",263.4,255.8,228.7,250.9,138,159.4,141,139.1,11.8,"","",210.2,193.6,181.6,181.7,99.4,159.4,114.9,111,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"Low","Master Protein","Q9UKZ9","Procollagen C-endopeptidase enhancer 2 OS=Homo sapiens OX=9606 GN=PCOLCE2 PE=1 SV=1",0.08,1.146,2,1,1,1,415,45.7,8.47,2.79,1,"regulation of biological process","extracellular","enzyme regulator activity;protein binding","Pf00431, Pf01759","26577","ENSG00000163710.7","PCOLCE2","3","","Collagen biosynthesis and modifying enzymes","",3,0,1.805,0.85,8.80810313574898e-10,2.10591711427882E-7,131.9,108.2,59.9,"",17.99,10.93,295.6,"","",257,251.7,233.3,168,130.1,138.5,109,139.2,15,"","",205.1,190.5,185.3,121.7,93.7,138.5,88.8,111.1,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P33121","Long-chain-fatty-acid--CoA ligase 1 OS=Homo sapiens OX=9606 GN=ACSL1 PE=1 SV=1",0,43.076,18,12,13,11,698,77.9,7.15,35.35,12,"metabolic process;regulation of biological process;response to stimulus;transport","endoplasmic reticulum;membrane;mitochondrion","catalytic activity;nucleotide binding","Pf00501","2180","ENSG00000151726.13","ACSL1","4","Adipocytokine signaling pathway; Fatty acid degradation; Fatty acid biosynthesis; Fatty acid metabolism; Metabolic pathways; PPAR signaling pathway; Peroxisome","Synthesis of very long-chain fatty acyl-CoAs; PPARA activates gene expression; Linoleic acid (LA) metabolism; alpha-linolenic acid (ALA) metabolism","Fatty Acid Beta Oxidation; Fatty Acid Biosynthesis; Mitochondrial LC-Fatty Acid Beta-Oxidation; PPAR signaling pathway",21,1,1.622,0.7,1.35851108140628E-9,3.12921430556119e-07,106,120,74,"",14.01,12.03,987.5,"","",1153,1083.5,1237.5,880.2,714.5,763.1,664.8,571.9,50.1,"","",920.1,820.1,982.7,637.5,514.6,763.1,541.8,456.4,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"Medium","Master Protein","Q8NB25","Protein FAM184A OS=Homo sapiens OX=9606 GN=FAM184A PE=2 SV=3",0.023,1.825,1,1,1,1,1140,132.9,5.83,3.12,1,"","","protein binding","Pf12128","79632","ENSG00000111879.18","FAM184A","6","","","",0,0,0.542,-0.88,4.07756806097836e-09,8.65360736356847e-07,69.7,80.9,149.4,"",32.91,8.15,78.8,"","",90.5,79.8,92.7,155.6,163.3,164.4,173.7,193.9,4,"","",72.2,60.4,73.6,112.7,117.6,164.4,141.6,154.7,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P21980","Protein-glutamine gamma-glutamyltransferase 2 OS=Homo sapiens OX=9606 GN=TGM2 PE=1 SV=2",0,88.015,26,16,26,16,687,77.3,5.22,85.54,16,"cell organization and biogenesis;cellular homeostasis;metabolic process;regulation of biological process;response to stimulus;transport","cytoplasm;cytosol;endoplasmic reticulum;membrane;mitochondrion","catalytic activity;metal ion binding;nucleotide binding;protein binding","Pf00868, Pf00927, Pf01841","7052","ENSG00000198959.11","TGM2","20","Huntington's disease","","",1,0,1.499,0.58,4.15995260460988e-09,8.73035386620794e-07,106.8,115.9,77.3,"",5.72,6.05,3569.5,"","",3900.7,4129.7,3848,3590.8,2442.8,2813.6,2540.3,2631.3,181.1,"","",3112.8,3125.8,3055.7,2600.6,1759.4,2813.6,2070.4,2099.7,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P78380","Oxidized low-density lipoprotein receptor 1 OS=Homo sapiens OX=9606 GN=OLR1 PE=1 SV=1",0,36.673,25,9,12,9,273,30.9,7.28,39.99,9,"cellular component movement;defense response;metabolic process;response to stimulus;transport","extracellular;membrane","protein binding;receptor activity","Pf00059","4973","ENSG00000173391.8","OLR1","12","PPAR signaling pathway; Phagosome","Neutrophil degranulation; Cell surface interactions at the vascular wall","PPAR signaling pathway",8,0,0.635,-0.66,4.32599622790519E-9,8.85448975216077e-07,85.6,83.3,131.2,"",19.25,6.58,798.2,"","",719.3,839.1,679.1,1029.5,1199.8,1322.9,1131.5,1248,40.5,"","",574,635.1,539.3,745.6,864.1,1322.9,922.2,995.9,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"Medium","Master Protein","O00444","Serine/threonine-protein kinase PLK4 OS=Homo sapiens OX=9606 GN=PLK4 PE=1 SV=3",0.015,2.086,1,1,2,1,970,108.9,8.62,6.03,1,"cell differentiation;cell organization and biogenesis;metabolic process;regulation of biological process","chromosome;cytoplasm;cytoskeleton;cytosol;nucleus","catalytic activity;nucleotide binding;protein binding","Pf00069, Pf00659, Pf07714","10733","ENSG00000142731.10","PLK4","4","FoxO signaling pathway","Regulation of PLK1 Activity at G2/M Transition; AURKA Activation by TPX2; Anchoring of the basal body to the plasma membrane; Recruitment of NuMA to mitotic centrosomes; Loss of Nlp from mitotic centrosomes; Recruitment of mitotic centrosome proteins and complexes","Retinoblastoma (RB) in Cancer",18,0,0.594,-0.75,4.35973923629263e-09,8.85448975216077e-07,80.6,81.8,137.6,"",28.45,11.16,297.6,"","",287.1,317.3,274.7,483.5,595.1,472,540.1,477.5,15.1,"","",229.1,240.2,218.1,350.2,428.6,472,440.2,381,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q9NZ63","Telomere length and silencing protein 1 homolog OS=Homo sapiens OX=9606 GN=C9orf78 PE=1 SV=1",0,59.833,44,13,17,13,289,33.7,6.74,52.81,13,"","cytosol","protein binding","Pf07052","51759","ENSG00000136819.15","C9orf78","9","","","",0,0,0.678,-0.56,5.75736391894566e-09,1.1568626563941E-6,149.3,60.9,89.8,86.33,20.22,8.49,2769.2,11447.7,"",2295.2,2246.1,2294.8,3302.9,3327.3,2870.1,3443.8,3466.9,140.5,3.2,"",1831.6,1700.1,1822.3,2392.1,2396.4,2870.1,2806.7,2766.5,"High","High","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P35354","Prostaglandin G/H synthase 2 OS=Homo sapiens OX=9606 GN=PTGS2 PE=1 SV=2",0,45.184,25,11,12,11,604,69,7.39,35.29,11,"cell differentiation;cellular component movement;defense response;metabolic process;regulation of biological process;response to stimulus","cytoplasm;endoplasmic reticulum;membrane;nucleus;organelle lumen","antioxidant activity;catalytic activity;metal ion binding;protein binding","Pf00008, Pf03098","5743","ENSG00000073756.11","PTGS2","1","Small cell lung cancer; Arachidonic acid metabolism; MicroRNAs in cancer; Regulation of lipolysis in adipocytes; Chemical carcinogenesis; Leishmaniasis; TNF signaling pathway; Pathways in cancer; Oxytocin signaling pathway; Metabolic pathways; VEGF signaling pathway; Retrograde endocannabinoid signaling; Ovarian steroidogenesis; NF-kappa B signaling pathway; Serotonergic synapse","Synthesis of 15-eicosatetraenoic acid derivatives; Interleukin-10 signaling; Interleukin-4 and 13 signaling; Synthesis of Prostaglandins (PG) and Thromboxanes (TX); Nicotinamide salvaging","Selenium Micronutrient Network; Eicosanoid Synthesis; Spinal Cord Injury; Quercetin and Nf-kB/ AP-1 Induced Cell Apoptosis; Aryl Hydrocarbon Receptor; Overview of nanoparticle effects; Photodynamic therapy-induced HIF-1 survival signaling; Photodynamic therapy-induced NF-kB survival signaling; Hepatitis C and Hepatocellular Carcinoma; VEGFA-VEGFR2 Signaling Pathway; Prostaglandin Synthesis and Regulation",41,0,1.526,0.61,6.70967104099418e-09,1.33402385918209E-6,187.8,67.8,44.4,100.31,13.35,6.02,1886.2,11090,"",1763,1546.4,1830.5,1353.8,1103.7,1138.8,1061.2,988.6,95.7,3.1,"",1406.9,1170.5,1453.6,980.5,794.9,1138.8,864.9,788.9,"High","High","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q9BQI0","Allograft inflammatory factor 1-like OS=Homo sapiens OX=9606 GN=AIF1L PE=1 SV=1",0,7.039,21,2,2,2,150,17.1,7.2,6.2,2,"","cytoplasm;cytoskeleton;membrane","metal ion binding;protein binding","Pf13499","83543","ENSG00000126878.12","AIF1L","9","","","",0,0,0.589,-0.76,1.24954535607458e-08,2.33677353322145e-06,84.6,79.8,135.6,"",9.55,3.47,222.7,"","",213,207.4,198.6,245.9,355.3,363.4,335.6,358.9,11.3,"","",170,157,157.7,178.1,255.9,363.4,273.5,286.4,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q9Y6C9","Mitochondrial carrier homolog 2 OS=Homo sapiens OX=9606 GN=MTCH2 PE=1 SV=1",0,46.175,25,9,15,9,303,33.3,7.97,42.27,9,"regulation of biological process;transport","membrane;mitochondrion;nucleus","","Pf00153","23788","ENSG00000109919.9","MTCH2","11","","","",0,0,0.69,-0.54,1.30969655121049E-8,2.42524984894743e-06,99.8,81.7,118.4,"",3.62,3.1,2769.2,"","",2228.7,2276,2256.9,2415.4,3263.6,3291.2,3278.7,3483.2,140.5,"","",1778.5,1722.7,1792.2,1749.3,2350.5,3291.2,2672.2,2779.5,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q9NQW6","Anillin OS=Homo sapiens OX=9606 GN=ANLN PE=1 SV=2",0,146.912,35,35,43,35,1124,124.1,8.07,118.53,35,"cell differentiation;cell division;cell organization and biogenesis;cellular component movement;regulation of biological process","cytoplasm;cytoskeleton;nucleus","protein binding","Pf00169, Pf08174","54443","ENSG00000011426.10","ANLN","7","","","Retinoblastoma (RB) in Cancer",1,0,0.693,-0.53,1.4574192963579E-8,2.63558424146635e-06,120.1,73.6,106.2,59.43,1.08,2.48,4527.4,11090,"",4344.2,4343,4253.9,4352.6,6117.1,6143.9,6385.6,6411,229.7,3.1,"",3466.7,3287.2,3378,3152.3,4405.7,6143.9,5204.3,5115.8,"High","High","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P04406","Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3",0,423.765,61,26,330,26,335,36,8.46,948.27,26,"cell death;cell organization and biogenesis;defense response;metabolic process;regulation of biological process;response to stimulus","cytoplasm;cytoskeleton;cytosol;membrane;nucleus","catalytic activity;enzyme regulator activity;nucleotide binding;protein binding","Pf00044, Pf02800","2597","ENSG00000111640.14","GAPDH","12","Carbon metabolism; Glycolysis / Gluconeogenesis; HIF-1 signaling pathway; Biosynthesis of amino acids; Metabolic pathways; Alzheimer's disease","Gluconeogenesis; Glycolysis","Cori Cycle; Alzheimers Disease; Glycolysis and Gluconeogenesis; Sudden Infant Death Syndrome (SIDS) Susceptibility Pathways",15,0,1.414,0.5,1.48343828332287e-08,2.64331908447192e-06,110,111.3,78.7,71.22,4.38,1.67,65361.8,11090,85266.1,68179.1,66671,65628,61485.9,47759.4,46575.1,46971,45888.9,3316.2,3.1,10.8,54407.2,50463.3,52114.9,44530.6,34397.6,46575.1,38281.9,36618.2,"High","High","High","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q9BXS6","Nucleolar and spindle-associated protein 1 OS=Homo sapiens OX=9606 GN=NUSAP1 PE=1 SV=1",0,106.516,44,19,35,19,441,49.4,9.91,110.53,19,"cell division;cell organization and biogenesis;metabolic process;regulation of biological process","chromosome;cytoplasm;cytoskeleton;nucleus","DNA binding;protein binding;RNA binding","","51203","ENSG00000137804.12","NUSAP1","15","","","",0,0,0.693,-0.53,1.60826001405212e-08,2.81266806902004e-06,87.6,87,125.4,"",2.71,3,2302.1,"","",2273.2,2288.1,2284,2406.4,3248.3,3183.6,3405.1,3346.3,116.8,"","",1814,1731.9,1813.7,1742.8,2339.5,3183.6,2775.2,2670.3,"High","Not Found","High","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q9NQS7","Inner centromere protein OS=Homo sapiens OX=9606 GN=INCENP PE=1 SV=3",0,64.797,22,19,24,19,918,105.4,9.44,51.94,19,"cell division;cell organization and biogenesis;metabolic process","chromosome;cytoplasm;cytoskeleton;cytosol;nucleus","protein binding","Pf03941, Pf12178","3619","ENSG00000149503.12","INCENP","11","","Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal; Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; SUMOylation of DNA replication proteins","",21,0,0.671,-0.58,1.66772828880113e-08,2.86364108353416e-06,172.5,51.2,76.3,108.55,1.83,3.47,1835,13951.9,"",1497.5,1478,1543.8,1508.1,2125.4,2206.1,2272.9,2297.7,93.1,3.9,"",1195,1118.7,1225.9,1092.2,1530.8,2206.1,1852.4,1833.5,"High","High","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P11388","DNA topoisomerase 2-alpha OS=Homo sapiens OX=9606 GN=TOP2A PE=1 SV=3",0,433.124,42,72,171,58,1531,174.3,8.72,523.84,72,"cell differentiation;cell division;cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus","chromosome;cytoplasm;nucleus","catalytic activity;DNA binding;metal ion binding;nucleotide binding;protein binding;RNA binding","Pf00204, Pf00521, Pf01751, Pf02518, Pf08070","7153","ENSG00000131747.14","TOP2A","17","Platinum drug resistance","SUMOylation of DNA replication proteins; Transcription of E2F targets under negative control by DREAM complex","Gastric Cancer Network 1; Gastric cancer network 2; Retinoblastoma (RB) in Cancer",14,17,0.708,-0.5,1.82722472708008E-8,2.94491005050672e-06,96.9,84.2,118.9,13.83,1.19,1.61,22343.1,27188.3,"",21442.5,21372.3,21832.1,21233.9,29758.8,30338.5,30107.2,30917.9,1133.6,7.6,"",17111.2,16176.7,17336.8,15378.5,21433.1,30338.5,24537.7,24671.7,"High","High","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P32929","Cystathionine gamma-lyase OS=Homo sapiens OX=9606 GN=CTH PE=1 SV=3",0,31.193,21,7,7,7,405,44.5,6.7,19.92,7,"cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus","cytoplasm;cytosol","catalytic activity;protein binding","Pf00155, Pf00266, Pf01041, Pf01053","1491","ENSG00000116761.11","CTH","1","Cysteine and methionine metabolism; Biosynthesis of amino acids; Glycine, serine and threonine metabolism; Metabolic pathways; Selenocompound metabolism","Metabolism of ingested SeMet, Sec, MeSec into H2Se; Degradation of cysteine and homocysteine; Cysteine formation from homocysteine","Selenium Micronutrient Network; Vitamin B12 Metabolism; Folate Metabolism; Trans-sulfuration pathway; Trans-sulfuration and one carbon metabolism; Amino Acid metabolism; One carbon metabolism and related pathways",19,0,0.667,-0.58,1.96967162580108e-08,3.10026313901091e-06,94.1,82.4,123.5,"",0.99,2.32,1799.5,"","",1588.5,1552.4,1580.2,1570.3,2359.7,2458.5,2332.9,2361.7,91.3,"","",1267.6,1175,1254.8,1137.3,1699.5,2458.5,1901.3,1884.6,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","O15392","Baculoviral IAP repeat-containing protein 5 OS=Homo sapiens OX=9606 GN=BIRC5 PE=1 SV=3",0,7.97,20,3,4,3,142,16.4,5.9,7.01,3,"cell death;cell division;cell organization and biogenesis;metabolic process;regulation of biological process","chromosome;cytoplasm;cytoskeleton;cytosol;nucleus","catalytic activity;enzyme regulator activity;metal ion binding;protein binding","Pf00653","332","","BIRC5","17","Pathways in cancer; Apoptosis - multiple species; Hepatitis B; Apoptosis; Hippo signaling pathway; Platinum drug resistance; Colorectal cancer","SUMOylation of DNA replication proteins; Neddylation; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal; Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; Interleukin-4 and 13 signaling; TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain","Interleukin-11 Signaling Pathway; Apoptosis; Apoptosis-related network due to altered Notch3 in ovarian cancer; Rac1/Pak1/p38/MMP-2 pathway; Photodynamic therapy-induced HIF-1 survival signaling; Photodynamic therapy-induced NF-kB survival signaling; Hepatitis C and Hepatocellular Carcinoma; IL-4 Signaling Pathway",47,0,0.628,-0.67,2.054925118955e-08,3.18142833170672e-06,82,84.1,133.9,"",5.98,3.65,394.2,"","",396.9,394,411.3,447.6,663.1,611.8,631.6,655.4,20,"","",316.7,298.2,326.6,324.2,477.6,611.8,514.8,523,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P25774","Cathepsin S OS=Homo sapiens OX=9606 GN=CTSS PE=1 SV=3",0.01,2.489,3,1,1,1,331,37.5,8.34,0,1,"cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus;transport","extracellular;organelle lumen;vacuole","catalytic activity;protein binding","Pf00112, Pf08246","1520","ENSG00000163131.10","CTSS","1","Phagosome; Antigen processing and presentation; Lysosome; Apoptosis; Tuberculosis","Degradation of the extracellular matrix; Neutrophil degranulation; Assembly of collagen fibrils and other multimeric structures; Endosomal/Vacuolar pathway; MHC class II antigen presentation; Trafficking and processing of endosomal TLR","",19,0,1.817,0.86,2.66767445911142E-8,3.9364871237263e-06,117.9,117.5,64.7,"",10.78,14.87,92.6,"","",84.8,94.7,89.9,108.5,47.2,63.9,47.2,54.6,4.7,"","",67.7,71.7,71.4,78.6,34,63.9,38.5,43.6,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P52943","Cysteine-rich protein 2 OS=Homo sapiens OX=9606 GN=CRIP2 PE=1 SV=1",0,38.241,24,4,10,4,208,22.5,8.72,36.7,4,"regulation of biological process","","metal ion binding;protein binding","Pf00412","1397","ENSG00000182809.10","CRIP2","14","","","",0,0,0.683,-0.55,3.63266319247657E-8,5.23769025797691e-06,106,78.7,115.3,"",21.44,8.4,1557.1,"","",1147.2,1163.7,1148.9,1706.9,1655.6,1503.7,1733.3,1839.5,79,"","",915.5,880.8,912.3,1236.2,1192.4,1503.7,1412.7,1467.9,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","O60488","Long-chain-fatty-acid--CoA ligase 4 OS=Homo sapiens OX=9606 GN=ACSL4 PE=1 SV=2",0,126.35,38,23,35,22,711,79.1,8.38,116.64,23,"cell differentiation;metabolic process;regulation of biological process;response to stimulus;transport","cytoplasm;endoplasmic reticulum;membrane;mitochondrion","catalytic activity;nucleotide binding","Pf00501","2182","ENSG00000068366.19","ACSL4","X","PPAR signaling pathway; Adipocytokine signaling pathway; Peroxisome; Fatty acid biosynthesis; Fatty acid degradation; Fatty acid metabolism; Metabolic pathways","Synthesis of very long-chain fatty acyl-CoAs","Fatty Acid Beta Oxidation; Fatty Acid Biosynthesis; Mitochondrial LC-Fatty Acid Beta-Oxidation; PPAR signaling pathway",16,1,1.398,0.48,4.31889985996747E-8,6.08771496679594e-06,153.2,85.6,61.2,72.77,8.57,6.12,7338,"",22895.5,7300.3,7179.3,7528.2,6164.5,5227.2,5735.7,5128.8,4997.8,372.3,"",2.9,5825.7,5434,5978.1,4464.6,3764.8,5735.7,4180,3988.1,"High","Not Found","High","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q92466","DNA damage-binding protein 2 OS=Homo sapiens OX=9606 GN=DDB2 PE=1 SV=1",0,61.791,38,12,15,12,427,47.8,9.47,46.27,12,"cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus","nucleus","catalytic activity;DNA binding;protein binding","Pf00400","1643","ENSG00000134574.11","DDB2","11","p53 signaling pathway; Ubiquitin mediated proteolysis; Nucleotide excision repair; Hepatitis B","Ub-specific processing proteases; Formation of Incision Complex in GG-NER; DNA Damage Recognition in GG-NER; TP53 Regulates Transcription of DNA Repair Genes; Dual Incision in GG-NER; Neddylation","miRNA Regulation of DNA Damage Response; DNA Damage Response",22,0,0.678,-0.56,5.22589029827714E-8,7.25783940837195E-6,90.5,84.6,124.9,"",5.08,2.68,1835,"","",1760.8,1648.4,1670.3,1839.7,2565.9,2426.3,2496.2,2567.9,93.1,"","",1405.1,1247.7,1326.4,1332.4,1848,2426.3,2034.4,2049.1,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P68431","Histone H3.1 OS=Homo sapiens OX=9606 GN=H3C1 PE=1 SV=2",0,32.65,40,10,137,1,136,15.4,11.12,226.83,10,"cell organization and biogenesis;coagulation;metabolic process;regulation of biological process;response to stimulus","chromosome;extracellular;membrane;nucleus","catalytic activity;DNA binding;protein binding","Pf00125, Pf15630","8968; 8352; 8351; 8355; 8357; 8358; 8350; 8353; 8354; 8356","ENSG00000197153.4; ENSG00000275379.1; ENSG00000278272.1; ENSG00000277775.1; ENSG00000273983.1; ENSG00000274750.2; ENSG00000274267.1; ENSG00000197409.7; ENSG00000275714.1; ENSG00000278828.1","HIST1H3F; HIST1H3C; HIST1H3D; HIST1H3G; HIST1H3H; HIST1H3B; HIST1H3A; HIST1H3E; HIST1H3I; HIST1H3J","6","Systemic lupus erythematosus; Alcoholism; Transcriptional misregulation in cancer","SIRT1 negatively regulates rRNA expression; RMTs methylate histone arginines; Activation of anterior HOX genes in hindbrain development during early embryogenesis; NoRC negatively regulates rRNA expression; Interleukin-7 signaling; Factors involved in megakaryocyte development and platelet production; Transcriptional regulation by small RNAs; Meiotic recombination; PRC2 methylates histones and DNA; HDACs deacetylate histones; Formation of the beta-catenin:TCF transactivating complex; DNA methylation; Amyloid fiber formation; RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function; RUNX1 regulates transcription of genes involved in differentiation of HSCs; RNA Polymerase I Chain Elongation; HDMs demethylate histones; PKMTs methylate histone lysines; HATs acetylate histones; Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3; ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression; Condensation of Prophase Chromosomes; Senescence-Associated Secretory Phenotype (SASP); B-WICH complex positively regulates rRNA expression; RNA Polymerase I Promoter Opening; Oxidative Stress Induced Senescence","Histone Modifications",64,8,0.718,-0.48,6.16019157906322e-08,8.25203535782597e-06,126.6,72.4,100.9,61.73,13.89,7.86,12490.1,31839,"",11301.8,11113.1,11516.2,14670.7,16464.9,16513.3,13912,15349,633.7,8.9,"",9018.9,8411.5,9145,10625.1,11858.5,16513.3,11338.4,12248.1,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P57764","Gasdermin-D OS=Homo sapiens OX=9606 GN=GSDMD PE=1 SV=1",0,37.493,13,6,10,6,484,52.8,5.08,38.07,6,"cell communication;cell death;cell organization and biogenesis;defense response;regulation of biological process;response to stimulus;transport","cytoplasm;cytosol;extracellular;membrane;organelle lumen","protein binding","Pf04598","79792","ENSG00000278718.3; ENSG00000104518.10","GSDMD","8; CHR_HSCHR8_3_CTG7","NOD-like receptor signaling pathway","Neutrophil degranulation","",4,0,1.497,0.58,7.52771545098341e-08,9.73859516699826e-06,106.9,115.8,77.3,"",3.01,2.04,1304.8,"","",1431.3,1459.4,1394.3,1362,955.1,923.2,932.7,964.8,66.2,"","",1142.2,1104.6,1107.2,986.4,687.9,923.2,760.2,769.9,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q05682","Caldesmon OS=Homo sapiens OX=9606 GN=CALD1 PE=1 SV=3",0,203.068,37,37,58,3,793,93.2,5.66,191.82,37,"cellular component movement","cytoplasm;cytoskeleton;cytosol;membrane","protein binding","Pf02029","800","ENSG00000122786.19","CALD1","7","Vascular smooth muscle contraction","Smooth Muscle Contraction","Myometrial Relaxation and Contraction Pathways",4,0,0.558,-0.84,1.15219970009406E-7,1.44124158512428E-5,91.3,74.7,133.9,"",36.2,36.03,53.2,"","",43,42.3,44.1,81.2,118.2,81.4,47.7,74.8,2.7,"","",34.3,32,35,58.8,85.1,81.4,38.9,59.7,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q6PCB6","Alpha/beta hydrolase domain-containing protein 17C OS=Homo sapiens OX=9606 GN=ABHD17C PE=1 SV=2",1E-3,4.154,5,2,2,2,329,35.8,5.64,2.55,2,"metabolic process;regulation of biological process","","catalytic activity","Pf00326, Pf01738, Pf02230, Pf05728, Pf12695, Pf12697","58489","ENSG00000136379.11","ABHD17C; FAM108C1","15","","","",0,0,1.702,0.77,1.19339385706851e-07,1.47325641649086e-05,110.4,119.4,70.2,"",9.83,12.01,96.6,"","",109.1,103.2,105.7,86.7,61.8,74.8,57.3,60.9,4.9,"","",87.1,78.1,83.9,62.8,44.5,74.8,46.7,48.6,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P01137","Transforming growth factor beta-1 proprotein OS=Homo sapiens OX=9606 GN=TGFB1 PE=1 SV=2",0,13.188,10,3,4,3,390,44.3,8.53,13.43,3,"cell death;cell differentiation;cell growth;cell organization and biogenesis;cell proliferation;cellular component movement;cellular homeostasis;defense response;metabolic process;regulation of biological process;response to stimulus;transport","cell surface;cytoplasm;extracellular;membrane;nucleus;organelle lumen","enzyme regulator activity;protein binding","Pf00019, Pf00688","7040","","TGFB1","19","Dilated cardiomyopathy; Chagas disease (American trypanosomiasis); Proteoglycans in cancer; MAPK signaling pathway; Osteoclast differentiation; Rheumatoid arthritis; Tuberculosis; Chronic myeloid leukemia; Endocytosis; Non-alcoholic fatty liver disease (NAFLD); Colorectal cancer; Hepatitis B; HTLV-I infection; Cytokine-cytokine receptor interaction; TGF-beta signaling pathway; Cell cycle; Pathways in cancer; Pancreatic cancer; Toxoplasmosis; Hippo signaling pathway; Inflammatory bowel disease (IBD); Intestinal immune network for IgA production; AGE-RAGE signaling pathway in diabetic complications; FoxO signaling pathway; Malaria; Leishmaniasis; Amoebiasis; Hypertrophic cardiomyopathy (HCM); Renal cell carcinoma","SMAD2/3 Phosphorylation Motif Mutants in Cancer; TGFBR2 Kinase Domain Mutants in Cancer; TGFBR1 LBD Mutants in Cancer; UCH proteinases; Transcriptional regulation of white adipocyte differentiation; Downregulation of TGF-beta receptor signaling; RUNX3 regulates p14-ARF; Molecules associated with elastic fibres; Syndecan interactions; Platelet degranulation ; ECM proteoglycans; TGFBR2 MSI Frameshift Mutants in Cancer; TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition); Cell surface interactions at the vascular wall; Regulation of RUNX3 expression and activity; Influenza Virus Induced Apoptosis; Interleukin-4 and 13 signaling; SMAD2/3 MH2 Domain Mutants in Cancer; TGFBR1 KD Mutants in Cancer; RUNX3 regulates CDKN1A transcription","MicroRNAs in cardiomyocyte hypertrophy; TFs Regulate miRNAs related to cardiac hypertrophy; Cell Cycle; Interleukin-11 Signaling Pathway; Corticotropin-releasing hormone signaling pathway; Adipogenesis; Cardiac Hypertrophic Response; Differentiation Pathway; IL-3 Signaling Pathway; Extracellular vesicle-mediated signaling in recipient cells; TGF-beta Signaling Pathway; MAPK Signaling Pathway; Endochondral Ossification; Cytokines and Inflammatory Response; ACE Inhibitor Pathway; TGF-beta Receptor Signaling; Senescence and Autophagy in Cancer; T-Cell antigen Receptor (TCR)  Signaling Pathway; DNA Damage Response (only ATM dependent)",98,0,1.637,0.71,1.55709175109209E-7,1.90976292172905e-05,102.9,122.3,74.8,"",11.49,8.87,394.2,"","",468.7,468.8,482.6,371.3,288.1,284.7,292.9,240,20,"","",374,354.8,383.2,268.9,207.5,284.7,238.7,191.5,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q99741","Cell division control protein 6 homolog OS=Homo sapiens OX=9606 GN=CDC6 PE=1 SV=1",0,52.973,22,13,15,13,560,62.7,9.58,44.88,13,"cell division;metabolic process;regulation of biological process","cytoplasm;cytosol;Golgi;nucleus","metal ion binding;nucleotide binding;protein binding","Pf00004, Pf09079, Pf13191, Pf13401","990","ENSG00000094804.9","CDC6","17","Cell cycle","CDT1 association with the CDC6:ORC:origin complex; Regulation of DNA replication; Activation of the pre-replicative complex; Association of licensing factors with the pre-replicative complex; CDK-mediated phosphorylation and removal of Cdc6; Orc1 removal from chromatin; M/G1 Transition; Activation of ATR in response to replication stress; Activation of E2F1 target genes at G1/S; CDC6 association with the ORC:origin complex; Transcription of E2F targets under negative control by DREAM complex; Removal of licensing factors from origins","Cell Cycle; DNA Replication",29,0,0.681,-0.55,1.89017496543542E-7,2.2885656889195e-05,82.5,88.1,129.4,"",7.45,0.92,910.6,"","",919.4,999.3,945.4,1086,1427.7,1428.4,1401.6,1426.7,46.2,"","",733.7,756.4,750.7,786.5,1028.3,1428.4,1142.3,1138.5,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P37268","Squalene synthase OS=Homo sapiens OX=9606 GN=FDFT1 PE=1 SV=1",0,91.529,43,16,20,16,417,48.1,6.54,62.15,16,"metabolic process;regulation of biological process","endoplasmic reticulum;membrane","catalytic activity;protein binding","Pf00494","2222","ENSG00000079459.12","FDFT1","8","Steroid biosynthesis; Metabolic pathways","Cholesterol biosynthesis; PPARA activates gene expression; Activation of gene expression by SREBF (SREBP)","Cholesterol Biosynthesis; Sterol Regulatory Element-Binding Proteins (SREBP) signalling; Statin Pathway",13,0,1.44,0.53,2.07640321603364e-07,2.48222176863566e-05,110.7,111.7,77.6,"",15.59,8.44,3790.2,"","",4040,3655.8,3997.6,2819.8,2642.8,2667.4,2767.3,2269.1,192.3,"","",3223.9,2767.1,3174.5,2042.2,1903.4,2667.4,2255.4,1810.7,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q9H2J7","Sodium-dependent neutral amino acid transporter B(0)AT2 OS=Homo sapiens OX=9606 GN=SLC6A15 PE=1 SV=1",0,50.987,9,6,10,6,730,81.8,5.19,37.33,6,"transport","membrane","transporter activity","Pf00209","55117","ENSG00000072041.16","SLC6A15","12","","Amino acid transport across the plasma membrane; Na+/Cl- dependent neurotransmitter transporters","NRF2 pathway",7,0,1.508,0.59,2.8798576034994e-07,3.21862428490513E-5,115.3,111,73.7,"",11.3,11.06,1324.5,"","",1280.7,1269.9,1332.6,1022.6,815.2,1015.3,877.9,803.9,67.2,"","",1022,961.2,1058.2,740.6,587.1,1015.3,715.5,641.5,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","O43653","Prostate stem cell antigen OS=Homo sapiens OX=9606 GN=PSCA PE=1 SV=2",0,38.089,16,2,9,2,114,12,4.94,43.66,2,"","","","","","","","","","","",0,0,1.492,0.58,3.13009976382617E-7,3.47772496112639e-05,93.6,123.6,82.8,"",26.57,26.27,544,"","",651,792.2,580.5,1041.9,423.2,520,445.6,728.5,27.6,"","",519.5,599.6,461,754.6,304.8,520,363.2,581.3,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q96FF9","Sororin OS=Homo sapiens OX=9606 GN=CDCA5 PE=1 SV=1",0,48.932,50,9,12,9,252,27.6,9.61,28.41,9,"cell division;cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus","chromosome;cytoplasm;cytosol;nucleus","protein binding","Pf09666","113130","ENSG00000146670.9","CDCA5","11","MicroRNAs in cancer","Establishment of Sister Chromatid Cohesion; Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion","",11,0,0.69,-0.53,3.45122971756595e-07,3.81209514066583e-05,80.7,89.6,129.7,"",6.96,6.81,825.8,"","",899.2,934.2,870.3,1019.8,1434,1308.4,1216.1,1346.9,41.9,"","",717.6,707.1,691.1,738.6,1032.8,1308.4,991.1,1074.8,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P49715","CCAAT/enhancer-binding protein alpha OS=Homo sapiens OX=9606 GN=CEBPA PE=1 SV=3",0,6.915,6,2,2,2,358,37.5,7.68,4.98,2,"cell differentiation;cell organization and biogenesis;development;metabolic process;regulation of biological process;response to stimulus","nucleus","DNA binding;protein binding","Pf00170, Pf07716","1050","ENSG00000245848.2","CEBPA","19","Non-alcoholic fatty liver disease (NAFLD); Pathways in cancer; Transcriptional misregulation in cancer; Acute myeloid leukemia","Transcriptional regulation of white adipocyte differentiation","Adipogenesis; Differentiation of white and brown adipocyte; Transcription factor regulation in adipogenesis; Pathways Affected in Adenoid Cystic Carcinoma; White fat cell differentiation; IL-4 Signaling Pathway",12,0,0.609,-0.72,4.25963836869769e-07,4.54553952022384e-05,59.2,91.1,149.7,"",13.85,11.22,86.7,"","",134.7,144.3,132.1,103,214.7,223.7,240.7,183.1,4.4,"","",107.5,109.2,104.9,74.6,154.6,223.7,196.2,146.1,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q86UY5","Protein FAM83A OS=Homo sapiens OX=9606 GN=FAM83A PE=1 SV=1",0,12.904,7,3,3,3,434,47.4,8.82,9.86,3,"cell proliferation;regulation of biological process;response to stimulus","cytoplasm","protein binding","Pf07894","84985","ENSG00000147689.16","FAM83A","8","","","",0,0,1.653,0.72,5.23275762498443e-07,5.55260258543292e-05,82.3,135.6,82.1,"",12.24,7.17,102.5,"","",172.4,167.9,170,131,97.6,107.1,110.4,95.1,5.2,"","",137.6,127.1,135,94.9,70.3,107.1,90,75.9,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q8N7C3","Probable E3 ubiquitin-protein ligase TRIML2 OS=Homo sapiens OX=9606 GN=TRIML2 PE=1 SV=1",0,15.308,8,3,4,3,387,44,5.72,12.18,3,"metabolic process;response to stimulus","","catalytic activity;protein binding","Pf00622, Pf13765","205860","","TRIML2","4","","","",0,0,0.629,-0.67,5.44636259203202e-07,5.71504981323893E-5,45.8,98.1,156.1,"",2.64,5.64,98.5,"","",211.2,209.7,211.3,221.9,317.7,325.3,358.8,347,5,"","",168.5,158.7,167.8,160.7,228.8,325.3,292.4,276.9,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q14534","Squalene monooxygenase OS=Homo sapiens OX=9606 GN=SQLE PE=1 SV=3",0,48.646,22,11,12,11,574,63.9,8.63,30.57,11,"metabolic process;regulation of biological process;response to stimulus","endoplasmic reticulum;membrane","catalytic activity;nucleotide binding","Pf08491","6713","ENSG00000104549.11","SQLE","8","Metabolic pathways; Steroid biosynthesis","Cholesterol biosynthesis; Activation of gene expression by SREBF (SREBP)","Cholesterol Biosynthesis; Sterol Regulatory Element-Binding Proteins (SREBP) signalling; Statin Pathway",11,0,1.467,0.55,5.5498722373315e-07,5.75966960542403e-05,111.8,111.9,76.3,"",14.08,11.78,1334.4,"","",1359.1,1312.6,1388.2,1002.4,993.3,939.6,881.8,749.1,67.7,"","",1084.6,993.5,1102.4,726,715.4,939.6,718.7,597.8,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"Medium","Master Protein","O14493","Claudin-4 OS=Homo sapiens OX=9606 GN=CLDN4 PE=1 SV=1",0.023,1.814,4,1,1,1,209,22.1,8.05,1.63,1,"defense response;metabolic process;regulation of biological process;response to stimulus;transport","membrane","catalytic activity;protein binding;receptor activity;signal transducer activity;structural molecule activity;transporter activity","Pf00822","1364","ENSG00000189143.9","CLDN4","7","Hepatitis C; Tight junction; Leukocyte transendothelial migration; Cell adhesion molecules (CAMs)","Tight junction interactions","",8,0,1.455,0.54,5.53442605299992E-7,5.75966960542403e-05,114.2,110.2,75.7,"",7.73,8.04,873.1,"","",821.4,887.7,864.3,742,525.7,639.4,573.5,584.5,44.3,"","",655.5,671.9,686.3,537.4,378.6,639.4,467.4,466.4,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q96K76-4","Isoform 4 of Ubiquitin carboxyl-terminal hydrolase 47 OS=Homo sapiens OX=9606 GN=USP47",0,141.661,29,35,47,35,1355,154.6,5.06,140.54,35,"metabolic process;regulation of biological process;response to stimulus","cytoplasm","catalytic activity;protein binding","Pf00443, Pf13423","55031","ENSG00000170242.17","USP47","11","","","",0,0,0.737,-0.44,6.48238204892237e-07,6.69066842295332e-05,89.4,89.4,121.2,"",1.24,4.96,5400.5,"","",5376.3,5468.7,5417,5310.2,7582,7446.9,7197.1,6764.6,274,"","",4290.3,4139.3,4301.6,3845.9,5460.8,7446.9,5865.7,5398,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P54652","Heat shock-related 70 kDa protein 2 OS=Homo sapiens OX=9606 GN=HSPA2 PE=1 SV=1",0,180.641,41,27,139,12,639,70,5.74,428.66,27,"cell differentiation;cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus","cell surface;cytoplasm;cytoskeleton;cytosol;membrane;mitochondrion;nucleus","nucleotide binding;protein binding","Pf00012, Pf06723","3306","ENSG00000126803.9","HSPA2","14","Estrogen signaling pathway; Toxoplasmosis; Spliceosome; Endocytosis; Antigen processing and presentation; Influenza A; Protein processing in endoplasmic reticulum; Epstein-Barr virus infection; Legionellosis; Measles; MAPK signaling pathway; Longevity regulating pathway - multiple species","Meiotic synapsis; Attenuation phase; HSP90 chaperone cycle for steroid hormone receptors (SHR); Regulation of HSF1-mediated heat shock response","Parkin-Ubiquitin Proteasomal System pathway",24,0,0.699,-0.52,6.68684355886739e-07,6.8641902793417e-05,183.3,48,68.7,119.27,1.71,2.6,1945.4,"",22895.5,1732.1,1721,1762.9,1786.7,2489.6,2546.7,2508.6,2394.9,98.7,"",2.9,1382.2,1302.6,1399.9,1294,1793.1,2546.7,2044.5,1911.1,"High","Not Found","High","High","High","High","High","High","High","High","High",1,""]
[false,"Medium","Master Protein","Q494V2","Cilia- and flagella-associated protein 100 OS=Homo sapiens OX=9606 GN=CFAP100 PE=2 SV=1",0.036,1.613,1,1,1,1,611,71.1,7.11,2.12,1,"cell organization and biogenesis;cellular component movement;regulation of biological process","cytoplasm;cytoskeleton","protein binding","Pf13863","348807","ENSG00000163885.11","CCDC37; CFAP100","3","","","",0,0,0.599,-0.74,7.50125012549674E-7,7.49648742700436e-05,95.4,76.7,128,"",67.34,25.48,151.8,"","",116.5,104.6,127.7,351.3,189.5,147.1,218.8,272.7,7.7,"","",93,79.2,101.4,254.4,136.5,147.1,178.3,217.6,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q53HL2","Borealin OS=Homo sapiens OX=9606 GN=CDCA8 PE=1 SV=2",0,51.99,41,11,13,11,280,31.3,9.86,31.59,11,"cell division;cell organization and biogenesis;metabolic process","chromosome;cytoplasm;cytoskeleton;cytosol;nucleus","protein binding","Pf10444, Pf10512","55143","ENSG00000134690.10","CDCA8","1","","Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal; Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; SUMOylation of DNA replication proteins","",21,0,0.711,-0.49,7.65808306546489e-07,7.61294068107899e-05,147.9,63.2,88.9,96.5,1.41,2.4,2229.2,11805.5,"",2177.1,2189.6,2199.4,2247.9,3068.8,3135.4,2964.7,3100.7,113.1,3.3,"",1737.3,1657.3,1746.5,1628,2210.2,3135.4,2416.3,2474.3,"High","High","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","O95235","Kinesin-like protein KIF20A OS=Homo sapiens OX=9606 GN=KIF20A PE=1 SV=1",0,96.172,24,17,24,17,890,100.2,6.92,76.47,17,"cell organization and biogenesis;cellular component movement;transport","cytoplasm;cytoskeleton;Golgi","catalytic activity;motor activity;nucleotide binding;protein binding;transporter activity","Pf00225","10112","ENSG00000112984.11","KIF20A","5","","COPI-dependent Golgi-to-ER retrograde traffic; Kinesins; MHC class II antigen presentation; Mitotic Telophase/Cytokinesis","",15,0,0.711,-0.49,7.85156982985313e-07,7.76442151551131e-05,91.8,86.5,121.7,"",3.4,2.23,1957.2,"","",1844.2,1841.5,1834.7,1967.2,2573.4,2502.5,2613,2632.9,99.3,"","",1471.7,1393.8,1456.9,1424.7,1853.4,2502.5,2129.6,2101,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P31431","Syndecan-4 OS=Homo sapiens OX=9606 GN=SDC4 PE=1 SV=2",0,12.097,12,2,2,2,198,21.6,4.5,7.6,2,"cell organization and biogenesis;cellular component movement;metabolic process;regulation of biological process;response to stimulus","cell surface;extracellular;membrane;organelle lumen","protein binding;receptor activity;signal transducer activity","Pf01034","6385","ENSG00000124145.6","SDC4","20","Proteoglycans in cancer; ECM-receptor interaction; Cell adhesion molecules (CAMs)","Defective B4GALT7 causes EDS, progeroid type; Retinoid metabolism and transport; Defective EXT2 causes exostoses 2; Syndecan interactions; Defective EXT1 causes exostoses 1, TRPS2 and CHDS; Signaling by GPCR; HS-GAG biosynthesis; A tetrasaccharide linker sequence is required for GAG synthesis; Cell surface interactions at the vascular wall; Defective B3GALT6 causes EDSP2 and SEMDJL1; HS-GAG degradation; Defective B3GAT3 causes JDSSDHD","",30,0,1.475,0.56,8.78708430906983e-07,8.55517775410881e-05,124.1,104.8,71.1,"",2.08,4.2,1281.1,"","",1114.9,1083.2,1081.9,1060,693.8,740,727.7,768.1,65,"","",889.7,819.9,859.1,767.7,499.7,740,593.1,612.9,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q53EP0","Fibronectin type III domain-containing protein 3B OS=Homo sapiens OX=9606 GN=FNDC3B PE=1 SV=2",0,39.962,11,11,11,11,1204,132.8,5.95,34.12,11,"","membrane","protein binding;RNA binding","Pf00041","64778","ENSG00000075420.12","FNDC3B","3","","","",0,0,1.451,0.54,9.50836760882368e-07,9.07040643411422E-5,110.3,112.3,77.4,"",6.8,4.25,845.6,"","",873.3,847.4,923.6,783.4,597,640.1,584.2,588.9,42.9,"","",696.9,641.4,733.4,567.4,430,640.1,476.1,469.9,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","O00767","Acyl-CoA desaturase OS=Homo sapiens OX=9606 GN=SCD PE=1 SV=2",0,26.258,9,4,8,4,359,41.5,9,22.16,4,"metabolic process;regulation of biological process","endoplasmic reticulum;membrane","catalytic activity;metal ion binding","Pf00487","6319","ENSG00000099194.5","SCD","10","Fatty acid metabolism; AMPK signaling pathway; Biosynthesis of unsaturated fatty acids; PPAR signaling pathway","Fatty acyl-CoA biosynthesis; Activation of gene expression by SREBF (SREBP)","Sterol Regulatory Element-Binding Proteins (SREBP) signalling; SREBF and miR33 in cholesterol and lipid homeostasis; Adipogenesis; Liver X Receptor Pathway; Fatty Acid Biosynthesis; Angiopoietin Like Protein 8 Regulatory Pathway; PPAR signaling pathway",18,0,1.414,0.5,1.92486971473116e-06,0.000176489995979816,103.9,114.9,81.2,"",7.56,7.21,1462.5,"","",1766.7,1646.7,1586.7,1473.1,1159.2,1209,1126.9,1016.9,74.2,"","",1409.8,1246.4,1260,1066.9,834.9,1209,918.4,811.5,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P04183","Thymidine kinase, cytosolic OS=Homo sapiens OX=9606 GN=TK1 PE=1 SV=2",0,49.363,38,10,16,10,234,25.5,8.51,42.98,10,"cell organization and biogenesis;metabolic process","cytoplasm;cytosol","catalytic activity;metal ion binding;nucleotide binding;protein binding","Pf00265","7083","ENSG00000167900.11","TK1","17","Drug metabolism - other enzymes; Metabolic pathways; Pyrimidine metabolism","Activation of E2F1 target genes at G1/S; Pyrimidine salvage","Fluoropyrimidine Activity",14,0,0.712,-0.49,2.07533447071917e-06,1.87554629104994E-4,92.5,86.3,121.2,"",2.89,3.98,1647.7,"","",1565.9,1559.3,1470.5,1516.8,2308.9,2137.4,2183.2,2113.5,83.6,"","",1249.6,1180.2,1167.7,1098.5,1662.9,2137.4,1779.3,1686.5,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","O43663","Protein regulator of cytokinesis 1 OS=Homo sapiens OX=9606 GN=PRC1 PE=1 SV=2",0,139.246,45,30,45,4,620,71.6,6.68,131.74,30,"cell division;cell organization and biogenesis;regulation of biological process","cytoplasm;cytoskeleton;cytosol;membrane;nucleus","protein binding","Pf03999","9055","ENSG00000198901.13","PRC1","15","","RHO GTPases activate CIT","",4,25,0.72,-0.47,2.37535660474464e-06,0.000213646359763889,139.8,67.1,93.1,99.05,9.07,4.49,3338.8,"",18948,3685.4,3903.8,3728.1,4463,5233.6,5037.3,5359.1,5606.7,169.4,"",2.4,2941,2954.8,2960.5,3232.3,3769.4,5037.3,4367.7,4474,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","O00469","Procollagen-lysine,2-oxoglutarate 5-dioxygenase 2 OS=Homo sapiens OX=9606 GN=PLOD2 PE=1 SV=2",0,43.822,18,12,12,12,737,84.6,6.71,33.15,12,"metabolic process;response to stimulus","endoplasmic reticulum;membrane","catalytic activity;metal ion binding","Pf03171","5352","ENSG00000152952.11","PLOD2","3","Lysine degradation","Collagen biosynthesis and modifying enzymes","",4,0,0.7,-0.51,2.54711705660604E-6,0.000226933712099882,94.9,84.5,120.6,"",6.36,2.44,540.1,"","",501.5,460.8,510.6,447.9,705.5,692.4,666.1,680.7,27.4,"","",400.2,348.8,405.5,324.4,508.1,692.4,542.9,543.2,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q16763","Ubiquitin-conjugating enzyme E2 S OS=Homo sapiens OX=9606 GN=UBE2S PE=1 SV=2",0,50.521,50,8,12,8,222,23.8,8.38,37.64,8,"cell division;cell organization and biogenesis;metabolic process","cytoplasm;cytosol","catalytic activity;nucleotide binding;protein binding","Pf00179","27338","ENSG00000108106.13","UBE2S","19","Ubiquitin mediated proteolysis","Synthesis of active ubiquitin: roles of E1 and E2 enzymes; Antigen processing: Ubiquitination & Proteasome degradation","",9,0,0.72,-0.47,2.99365149336595e-06,0.000262995764682307,82,91.3,126.8,"",3.09,4.54,1164.9,"","",1281.1,1321,1233.7,1313.7,1825.3,1778.9,1934.1,1744.2,59.1,"","",1022.3,999.9,979.7,951.4,1314.6,1778.9,1576.3,1391.8,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P12277","Creatine kinase B-type OS=Homo sapiens OX=9606 GN=CKB PE=1 SV=1",0,58.407,40,11,19,11,381,42.6,5.59,58.24,11,"cellular homeostasis;metabolic process","cytoplasm;cytosol;mitochondrion;nucleus","catalytic activity;nucleotide binding;protein binding","Pf00217, Pf02807","1152","ENSG00000166165.12","CKB","14","Metabolic pathways; Arginine and proline metabolism","Creatine metabolism","Urea cycle and metabolism of amino groups",7,0,1.37,0.45,3.39220964407083e-06,0.000295262929756728,107.8,111.1,81.1,"",7.83,13.85,3198.9,"","",3229.9,2838.7,3361.8,3376.2,2539.6,2134,2912,2278.3,162.3,"","",2577.5,2148.6,2669.6,2445.2,1829.1,2134,2373.3,1818,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q14807","Kinesin-like protein KIF22 OS=Homo sapiens OX=9606 GN=KIF22 PE=1 SV=5",0,99.364,34,16,21,16,665,73.2,9.45,65.6,16,"cell organization and biogenesis;cellular component movement;metabolic process;response to stimulus;transport","chromosome;cytoplasm;cytoskeleton;cytosol;nucleus","catalytic activity;DNA binding;motor activity;nucleotide binding;protein binding","Pf00225, Pf12836","3835","ENSG00000079616.12","KIF22","16","","COPI-dependent Golgi-to-ER retrograde traffic; Kinesins; MHC class II antigen presentation","",11,0,0.717,-0.48,3.55418696362797e-06,0.000307942584261491,201.1,41.3,57.6,128.13,2.62,3.36,1129.4,"",22895.5,1065.2,1024,1075.8,1023.3,1457.2,1415.6,1533.5,1455.6,57.3,"",2.9,850,775.1,854.3,741.1,1049.5,1415.6,1249.8,1161.5,"High","Not Found","High","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P09038-1","Isoform 2 of Fibroblast growth factor 2 OS=Homo sapiens OX=9606 GN=FGF2",0,13.176,19,4,5,4,210,22.6,10.54,10.21,4,"cell differentiation;cell organization and biogenesis;cell proliferation;cellular component movement;cellular homeostasis;metabolic process;regulation of biological process;response to stimulus;transport","extracellular;nucleus","catalytic activity;protein binding","Pf00167, Pf00340","2247","","FGF2","4","","","MicroRNAs in cardiomyocyte hypertrophy; Cardiac Hypertrophic Response; Endochondral Ossification; Regulation of Actin Cytoskeleton",4,0,1.554,0.64,4.30244393312407e-06,3.62788218789497E-4,114.1,113.1,72.8,"",9.64,5.98,236.5,"","",194.6,229.1,240,241.4,151.3,150.5,134.7,154.4,12,"","",155.3,173.4,190.6,174.8,109,150.5,109.8,123.2,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q08378","Golgin subfamily A member 3 OS=Homo sapiens OX=9606 GN=GOLGA3 PE=1 SV=2",0,179.203,29,42,48,42,1498,167.3,5.44,152.22,42,"metabolic process;regulation of biological process;transport","cytoplasm;cytosol;Golgi;membrane;nucleus","catalytic activity;motor activity;protein binding;structural molecule activity;transporter activity","Pf00038, Pf01576, Pf02463, Pf04111, Pf05557, Pf07888, Pf10186, Pf12128, Pf12325","2802","ENSG00000090615.14","GOLGA3","12","","","",0,0,0.743,-0.43,4.34627608059124e-06,0.000364855389378699,126.3,74.1,99.6,67.95,2.06,2.8,2887.5,8228.1,"",2816.8,2838.2,2878.6,2951.4,3815.3,3825.8,3864.2,4048.7,146.5,2.3,"",2247.8,2148.2,2285.9,2137.5,2747.9,3825.8,3149.4,3230.8,"High","High","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q9H5V8","CUB domain-containing protein 1 OS=Homo sapiens OX=9606 GN=CDCP1 PE=1 SV=3",0,27.172,9,6,7,6,836,92.9,7.96,20.77,6,"","extracellular;membrane","protein binding","","64866","ENSG00000163814.7","CDCP1","3","","","",0,0,1.434,0.52,4.47451557561429e-06,3.73958629169039E-4,226.9,43.1,30,129.66,7.52,5.57,1198.4,"",27632.5,1119.3,1112,1074.1,946.9,708.2,803.5,742.6,782,60.8,"",3.5,893.2,841.7,852.9,685.8,510.1,803.5,605.2,624,"High","Not Found","High","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q02388","Collagen alpha-1(VII) chain OS=Homo sapiens OX=9606 GN=COL7A1 PE=1 SV=2",0,36.939,5,10,10,10,2944,295,6.27,29.73,10,"cell differentiation;cell organization and biogenesis;metabolic process;regulation of biological process;transport","extracellular;membrane;organelle lumen","enzyme regulator activity;protein binding","Pf00014, Pf00041, Pf00092, Pf01391, Pf13519","1294","ENSG00000114270.17","COL7A1","3","Protein digestion and absorption","Collagen degradation; Integrin cell surface interactions; Laminin interactions; Collagen chain trimerization; Cargo concentration in the ER; COPII (Coat Protein 2) Mediated Vesicle Transport; Anchoring fibril formation","",20,0,1.557,0.64,4.51490338138072e-06,0.000374024101173329,102.1,120.5,77.4,"",21.84,12.04,183.3,"","",221.9,210.6,251.6,144.4,132,146.1,167.2,129.5,9.3,"","",177.1,159.4,199.8,104.6,95.1,146.1,136.3,103.3,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q96KQ7-2","Isoform 2 of Histone-lysine N-methyltransferase EHMT2 OS=Homo sapiens OX=9606 GN=EHMT2",0,117.147,23,26,33,25,1176,128.9,5.54,102.65,26,"cell communication;cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus","nucleus","catalytic activity;metal ion binding;protein binding","Pf00023, Pf00856, Pf05033, Pf12796, Pf13606, Pf13637, Pf13857","10919","ENSG00000227333.8; ENSG00000236759.7; ENSG00000206376.9; ENSG00000204371.11","EHMT2","6; CHR_HSCHR6_MHC_DBB_CTG1; CHR_HSCHR6_MHC_COX_CTG1; CHR_HSCHR6_MHC_QBL_CTG1","","","Histone Modifications",1,1,0.726,-0.46,4.64608396399946e-06,0.000383210628436776,90.8,88,121.3,"",0.97,1.62,2215.4,"","",2146.6,2111.5,2148.7,2159.4,3045.8,2937.4,2951.9,2968.6,112.4,"","",1713,1598.2,1706.3,1563.9,2193.7,2937.4,2405.8,2368.9,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q13015","Protein AF1q OS=Homo sapiens OX=9606 GN=MLLT11 PE=1 SV=1",1E-3,5.014,13,1,1,1,90,10.1,4.54,3.32,1,"regulation of biological process;response to stimulus","cytoplasm;cytoskeleton;cytosol;nucleus","","Pf15017","10962","ENSG00000213190.3","MLLT11","1","","","",0,0,1.697,0.76,4.78303088291554e-06,3.92790814419603E-4,128.2,108.1,63.7,"",14.13,18.26,69,"","",56.8,62.6,59.6,44.6,46.7,34.8,33.7,31.8,3.5,"","",45.3,47.4,47.3,32.3,33.6,34.8,27.5,25.4,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q9Y4K0","Lysyl oxidase homolog 2 OS=Homo sapiens OX=9606 GN=LOXL2 PE=1 SV=1",0,31.067,11,7,7,7,774,86.7,6.38,20.9,7,"cell organization and biogenesis;cell proliferation;cellular component movement;metabolic process;regulation of biological process;response to stimulus;transport","chromosome;extracellular;membrane;nucleus","catalytic activity;metal ion binding;protein binding;receptor activity","Pf00530, Pf01186","4017","ENSG00000134013.15","LOXL2","8","","Elastic fibre formation; Crosslinking of collagen fibrils","Canonical and Non-Canonical TGF-B signaling",6,0,1.445,0.53,6.20502355275221e-06,0.000505174503725792,109.9,112.4,77.7,"",7.52,3.46,557.8,"","",601.1,563.7,576.8,502,384.2,416.8,394.6,394.4,28.3,"","",479.7,426.7,458,363.6,276.7,416.8,321.6,314.7,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P21589","5'-nucleotidase OS=Homo sapiens OX=9606 GN=NT5E PE=1 SV=1",0,7.858,5,2,2,2,574,63.3,7.03,6.6,2,"metabolic process;regulation of biological process","cell surface;cytosol;membrane","catalytic activity;metal ion binding;nucleotide binding","Pf00149, Pf02872, Pf09587","4907","ENSG00000135318.11","NT5E","6","Metabolic pathways; Purine metabolism; Pyrimidine metabolism; Nicotinate and nicotinamide metabolism","Pyrimidine catabolism; Purine catabolism; Nicotinate metabolism","Differentiation Pathway; NAD+ metabolism",14,0,1.619,0.7,6.29271536167764E-6,0.000507935075860544,95.7,126.3,78,"",8.73,9.68,57.2,"","",71.8,69.5,83.9,79.3,42.5,50.1,43.3,51.3,2.9,"","",57.3,52.6,66.6,57.4,30.6,50.1,35.3,40.9,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P98082","Disabled homolog 2 OS=Homo sapiens OX=9606 GN=DAB2 PE=1 SV=3",0,231.6,41,26,78,26,770,82.4,5.53,256.68,26,"cell death;cell differentiation;cell organization and biogenesis;cell proliferation;development;regulation of biological process;response to stimulus;transport","cytoplasm;cytosol;membrane","protein binding;receptor activity","Pf00640","1601","ENSG00000153071.14","DAB2","5","Endocytosis","Cargo recognition for clathrin-mediated endocytosis; Formation of annular gap junctions","Endoderm Differentiation; TGF-beta Signaling Pathway",11,0,0.759,-0.4,6.49772383987113e-06,0.000522251097393557,90.2,90.5,119.3,4.39,3.04,2.74,8755.1,8228.1,"",8385.9,8645.7,8186,8759.5,11666.3,10917.4,11204,11247.1,444.2,2.3,"",6692,6543.9,6500.5,6344,8402.4,10917.4,9131.4,8974.9,"High","High","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P07339","Cathepsin D OS=Homo sapiens OX=9606 GN=CTSD PE=1 SV=1",0,100.619,35,16,31,16,412,44.5,6.54,100.95,16,"metabolic process;transport","extracellular;membrane;organelle lumen;vacuole","catalytic activity;protein binding","Pf00026, Pf07966, Pf14541, Pf14543","1509","ENSG00000117984.13","CTSD","11","Sphingolipid signaling pathway; Lysosome; Apoptosis; Tuberculosis","Collagen degradation; Metabolism of Angiotensinogen to Angiotensins; Neutrophil degranulation; MHC class II antigen presentation","Prolactin Signaling Pathway",16,0,1.343,0.43,6.71079477942982e-06,0.00053709106692318,184.6,66.1,49.2,112.34,10.2,5.42,5158.1,"",45001.6,5614.3,5307.2,5682.3,4509,3938.2,4169.2,4418.3,3961.9,261.7,"",5.7,4480.2,4017,4512.3,3265.6,2836.4,4169.2,3601,3161.5,"High","Not Found","High","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","O00151","PDZ and LIM domain protein 1 OS=Homo sapiens OX=9606 GN=PDLIM1 PE=1 SV=4",0,72.923,54,14,21,14,329,36,7.02,61.78,14,"regulation of biological process;response to stimulus","cytoplasm;cytoskeleton","metal ion binding;protein binding","Pf00412, Pf00595, Pf13180","9124","ENSG00000107438.8","PDLIM1","10","","","",0,0,0.747,-0.42,7.0958108258079e-06,5.60776882334141E-4,190.5,46.8,62.7,125.03,5.19,1.77,1214.1,"",19737.5,1178.2,1199.6,1205.5,1319.6,1612.4,1590,1657.4,1608.8,61.6,"",2.5,940.2,908,957.3,955.7,1161.3,1590,1350.8,1283.8,"High","Not Found","High","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P49454","Centromere protein F OS=Homo sapiens OX=9606 GN=CENPF PE=1 SV=3",0,265.928,24,70,77,70,3114,357.3,5.1,229.11,70,"","","","","","","","","","","",0,0,0.763,-0.39,9.81705291036583e-06,0.000763063766958806,95.1,88.7,116.3,"",2.04,2.98,6460.9,"","",5963,5932.1,6200.4,6088.6,7838.8,7515,8047.2,7963.4,327.8,"","",4758.5,4490,4923.7,4409.6,5645.7,7515,6558.6,6354.6,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q9C0D2","Centrosomal protein of 295 kDa OS=Homo sapiens OX=9606 GN=CEP295 PE=1 SV=4",0,38.34,4,8,9,8,2601,295,6,34.48,8,"regulation of biological process","cytoplasm;cytoskeleton","","Pf15309","85459","ENSG00000166004.14","KIAA1731; CEP295","11","","","",0,0,0.661,-0.6,1.03469316095062E-5,7.97685078532051E-4,107.6,76.6,115.8,"",5.5,6.36,344.9,"","",244.5,230.7,263.7,246.6,385.2,398.7,357.9,347.5,17.5,"","",195.1,174.6,209.4,178.6,277.4,398.7,291.7,277.3,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q9Y6A5","Transforming acidic coiled-coil-containing protein 3 OS=Homo sapiens OX=9606 GN=TACC3 PE=1 SV=1",0,109.578,33,25,27,25,838,90.3,5.05,88.34,25,"cell division;cell organization and biogenesis;cell proliferation;metabolic process;regulation of biological process","cytoplasm;cytoskeleton","protein binding","Pf05010, Pf05149, Pf05557","10460","ENSG00000013810.18","TACC3","4","RNA transport","","",1,0,0.741,-0.43,1.19451859608155e-05,0.000913444017926653,163.8,58,78.2,111.5,1.71,3.39,2708.1,"",22895.5,2796,2775.4,2696.3,2795.3,3867.1,3708.8,3807.7,3576.9,137.4,"",2.9,2231.2,2100.7,2141.1,2024.5,2785.2,3708.8,3103.3,2854.3,"High","Not Found","High","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q02338","D-beta-hydroxybutyrate dehydrogenase, mitochondrial OS=Homo sapiens OX=9606 GN=BDH1 PE=1 SV=3",0.004,3.197,3,1,1,1,343,38.1,8.95,2.87,1,"metabolic process","membrane;mitochondrion;organelle lumen","catalytic activity","Pf00106","622","ENSG00000275544.4; ENSG00000161267.11","BDH1","3; CHR_HSCHR3_2_CTG3","Synthesis and degradation of ketone bodies; Metabolic pathways; Butanoate metabolism","Synthesis of Ketone Bodies; Utilization of Ketone Bodies","Synthesis and Degradation of Ketone Bodies",9,0,1.552,0.63,1.21257197920333e-05,0.000923510465451307,122.8,107.8,69.4,"",8.13,5.26,230.6,"","",186.3,190,217.5,215.5,133.8,127,121.5,136.6,11.7,"","",148.7,143.8,172.7,156.1,96.4,127,99,109,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P35527","Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3",0,107.035,37,18,46,17,623,62,5.24,135.84,18,"cell death;cell organization and biogenesis","cytosol;membrane;nucleus","structural molecule activity","Pf00038, Pf13166","3857","ENSG00000171403.9","KRT9","17","","Formation of the cornified envelope","",3,0,1.331,0.41,1.31174919737465e-05,0.000995032885141056,223.6,43.6,32.8,"",116.12,23.42,8205.2,"","",1455.1,1762.5,9999.9,1378.3,1032,947.8,1402.4,1548.8,416.3,"","",1161.2,1334,7940.9,998.2,743.3,947.8,1143,1235.9,"High","High","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P61764-2","Isoform 2 of Syntaxin-binding protein 1 OS=Homo sapiens OX=9606 GN=STXBP1",0,90.099,32,19,27,19,603,68.7,6.77,83.12,19,"cell communication;cell organization and biogenesis;regulation of biological process;response to stimulus;transport","cytoplasm;cytoskeleton;cytosol;membrane;mitochondrion","protein binding;RNA binding","Pf00995","6812","ENSG00000136854.19","STXBP1","9","","","Synaptic Vesicle Pathway; EGF/EGFR Signaling Pathway; Insulin Signaling",3,0,0.752,-0.41,1.39784674273447E-5,0.00105189359668401,143.9,67,89.1,95.8,2.5,2.71,2132.6,11090,"",2351.1,2234.4,2290.9,2229.9,3158,3012.2,3007,2972.4,108.2,3.1,"",1876.2,1691.2,1819.2,1615,2274.5,3012.2,2450.7,2371.9,"High","High","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q9H2F3","3 beta-hydroxysteroid dehydrogenase type 7 OS=Homo sapiens OX=9606 GN=HSD3B7 PE=1 SV=2",0,13.276,9,3,3,3,369,41,8.25,8.52,3,"cellular component movement;metabolic process;response to stimulus","endoplasmic reticulum;membrane","catalytic activity;protein binding","Pf00106, Pf01073, Pf01370, Pf07993, Pf13460","80270","ENSG00000099377.13","HSD3B7","16","Metabolic pathways; Primary bile acid biosynthesis","Synthesis of bile acids and bile salts via 27-hydroxycholesterol; Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol; Synthesis of bile acids and bile salts via 24-hydroxycholesterol","",10,0,1.546,0.63,1.7428236757322e-05,1.28587709325116E-3,122.3,107.9,69.8,"",17.85,18.86,138,"","",132.6,111.6,140.9,93.5,57.3,78.2,92.4,79.2,7,"","",105.8,84.5,111.9,67.7,41.3,78.2,75.3,63.2,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q99661","Kinesin-like protein KIF2C OS=Homo sapiens OX=9606 GN=KIF2C PE=1 SV=2",0,146.922,38,23,40,18,725,81.3,7.83,130.53,23,"cell division;cell organization and biogenesis;cell proliferation;cellular component movement;regulation of biological process;transport","chromosome;cytoplasm;cytoskeleton;cytosol;membrane;nucleus","catalytic activity;DNA binding;motor activity;nucleotide binding;protein binding","Pf00225","11004","ENSG00000142945.12","KIF2C","1","","COPI-dependent Golgi-to-ER retrograde traffic; Kinesins; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal; Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; MHC class II antigen presentation","Regulation of Microtubule Cytoskeleton",28,1,0.741,-0.43,1.82524249046079e-05,1.34144669882581E-3,92.4,88.3,119.3,"",1.92,1.27,4103.6,"","",3930.6,3908.3,3919.4,4069.9,5254.9,5240.7,5377.2,5346.2,208.2,"","",3136.6,2958.2,3112.4,2947.6,3784.7,5240.7,4382.5,4266.1,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q12840","Kinesin heavy chain isoform 5A OS=Homo sapiens OX=9606 GN=KIF5A PE=1 SV=2",0,38.332,8,10,12,1,1032,117.3,5.9,24.7,10,"cell communication;cellular component movement;metabolic process;transport","cytoplasm;cytoskeleton;cytosol;membrane","catalytic activity;motor activity;nucleotide binding;protein binding","Pf00225, Pf04111, Pf04156, Pf12128","3798","ENSG00000155980.11","KIF5A","12","Dopaminergic synapse; Endocytosis","COPI-dependent Golgi-to-ER retrograde traffic; Kinesins; RHO GTPases activate KTN1; Insulin processing; MHC class II antigen presentation","",20,0,0.645,-0.63,1.857893097168E-5,1.36015057439183E-3,101.4,77.9,120.7,"",76.58,25.34,177.4,"","",132.2,121.7,140.4,457,204.1,121.7,229.8,218.7,9,"","",105.5,92.1,111.5,331,147,121.7,187.3,174.5,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","O96006","Zinc finger BED domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ZBED1 PE=1 SV=1",0,22.367,8,4,4,4,694,78.1,6.1,15.27,4,"metabolic process;regulation of biological process","chromosome;membrane;nucleus","catalytic activity;DNA binding;metal ion binding;protein binding","Pf02892, Pf05699, Pf14372","9189","ENSG00000214717.11","ZBED1","X|Y; X","","SUMOylation of chromatin organization proteins","",5,0,0.674,-0.57,1.99993607916671E-5,1.45848620321625E-3,92.7,83.5,123.8,"",7.35,10.47,250.3,"","",242.5,230.9,219.9,203.8,293.5,329.8,379,339.1,12.7,"","",193.5,174.8,174.6,147.6,211.4,329.8,308.9,270.6,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q9Y6K1","DNA (cytosine-5)-methyltransferase 3A OS=Homo sapiens OX=9606 GN=DNMT3A PE=1 SV=4",0,48.107,15,13,16,10,912,101.8,6.57,41.34,13,"cell death;cell differentiation;cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus","chromosome;cytoplasm;nucleus","catalytic activity;DNA binding;metal ion binding;protein binding","Pf00145, Pf00855","1788","ENSG00000119772.16","DNMT3A","2","Cysteine and methionine metabolism; MicroRNAs in cancer; Metabolic pathways","PRC2 methylates histones and DNA; DNA methylation; RMTs methylate histone arginines","One Carbon Metabolism; Trans-sulfuration and one carbon metabolism; Hematopoietic Stem Cell Gene Regulation by GABP alpha/beta Complex; One carbon metabolism and related pathways",14,2,0.711,-0.49,2.07575027606488e-05,1.50795273901206E-3,90.3,87.1,122.6,"",2.31,4.85,672.1,"","",650.4,646.3,676.6,643.8,984.8,909.7,914.8,879,34.1,"","",519,489.2,537.3,466.3,709.3,909.7,745.6,701.4,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q9NUK0","Muscleblind-like protein 3 OS=Homo sapiens OX=9606 GN=MBNL3 PE=1 SV=2",0,31.701,19,9,15,4,354,38.5,8.81,35.92,9,"development;metabolic process;regulation of biological process","cytoplasm;nucleus","metal ion binding;protein binding;RNA binding","","55796","ENSG00000076770.14","MBNL3","X","","","",0,0,0.738,-0.44,2.14283374693203e-05,1.54480319893329E-3,102.5,83.9,113.6,"",2.24,10.93,1080.1,"","",867.8,866.6,899.9,903,1052.9,1112.9,1288.1,1319.1,54.8,"","",692.5,655.9,714.6,654,758.3,1112.9,1049.8,1052.6,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","O94907","Dickkopf-related protein 1 OS=Homo sapiens OX=9606 GN=DKK1 PE=1 SV=1",0,17.452,16,4,4,4,266,28.7,8.4,13.17,4,"cell organization and biogenesis;development;regulation of biological process;response to stimulus","extracellular;membrane","protein binding;signal transducer activity","Pf04706","22943","ENSG00000107984.9","DKK1","10","Wnt signaling pathway","Negative regulation of TCF-dependent signaling by WNT ligand antagonists; Misspliced LRP5 mutants have enhanced beta-catenin-dependent signaling","Cardiac Progenitor Differentiation; Primary Focal Segmental Glomerulosclerosis FSGS; Differentiation Pathway; Endoderm Differentiation; Mesodermal Commitment Pathway; Wnt/beta-catenin Signaling Pathway in Leukemia; VEGFA-VEGFR2 Signaling Pathway; EDA Signalling in Hair Follicle Development; Role of Osx and miRNAs in tooth development",18,0,0.639,-0.65,2.302203556237e-05,1.64712199887138E-3,"",117,183,"",25.21,6.66,"","","",55.3,86.5,80.3,105.2,117,133.1,127.9,136.7,"","","",44.1,65.5,63.8,76.2,84.3,133.1,104.2,109.1,"Not Found","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q9HCY8","Protein S100-A14 OS=Homo sapiens OX=9606 GN=S100A14 PE=1 SV=1",0,37.368,65,7,11,7,104,11.7,5.24,32.85,7,"cell death;defense response;regulation of biological process;response to stimulus","cytoplasm;cytosol","metal ion binding;protein binding","Pf01023","57402","ENSG00000189334.8","S100A14","1","","","",0,0,1.342,0.42,2.31528180572038E-5,1.6502280281678E-3,103.3,112.7,84,"",8.89,6.84,1630,"","",1770.9,1785.7,1811,1486.2,1363.5,1438.5,1287.1,1229.5,82.7,"","",1413.2,1351.6,1438.1,1076.4,982,1438.5,1049,981.1,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q8WVV4-1","Isoform 1 of Protein POF1B OS=Homo sapiens OX=9606 GN=POF1B",0,22.152,11,7,7,7,595,68.7,6.35,19.16,7,"cell organization and biogenesis","","protein binding","","79983","ENSG00000124429.17","POF1B","X","","","",0,0,1.407,0.49,2.45669677141347e-05,0.0017379059407662,118.5,106.1,75.4,"",0.54,3.43,618.9,"","",554,554.6,551.8,558.9,416.7,384.8,393.2,394.5,31.4,"","",442.1,419.8,438.2,404.8,300.1,384.8,320.5,314.8,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","O95671","Probable bifunctional dTTP/UTP pyrophosphatase/methyltransferase protein OS=Homo sapiens OX=9606 GN=ASMTL PE=1 SV=3",0,37.41,14,7,9,7,621,68.8,6.07,35.24,7,"metabolic process","cytoplasm;cytosol","catalytic activity;protein binding","Pf00891, Pf02545, Pf08241, Pf08242, Pf12847, Pf13649, Pf13659","8623","ENSG00000169093.15","ASMTL","X|Y; X","","","",0,0,1.382,0.47,2.55016989896273E-5,1.79061743686275E-3,125.5,101.2,73.2,"",9.28,4.32,938.2,"","",790.5,745.7,767.9,636.5,574.5,552.7,517.7,542.2,47.6,"","",630.8,564.4,609.8,461,413.8,552.7,421.9,432.7,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P22004","Bone morphogenetic protein 6 OS=Homo sapiens OX=9606 GN=BMP6 PE=1 SV=1",0,14.668,5,2,2,2,513,57.2,8.1,8.26,2,"cell differentiation;cellular homeostasis;defense response;development;regulation of biological process;response to stimulus","cytoplasm;extracellular","protein binding","Pf00019, Pf00688","654","ENSG00000153162.8","BMP6","6","Hippo signaling pathway; TGF-beta signaling pathway; Ovarian steroidogenesis","","Hfe effect on hepcidin production; Endochondral Ossification",5,0,1.708,0.77,2.75441129407028E-5,0.00191269560744116,145.4,97.5,57.1,"",34.86,27.51,45.3,"","",29.7,34.9,31.1,13.4,11,15.9,21.5,19.9,2.3,"","",23.7,26.4,24.7,9.7,7.9,15.9,17.5,15.9,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q6UVK1","Chondroitin sulfate proteoglycan 4 OS=Homo sapiens OX=9606 GN=CSPG4 PE=1 SV=2",0,315.71,27,52,83,52,2322,250.4,5.47,270.27,52,"cell differentiation;cell proliferation;cellular component movement;development;metabolic process;regulation of biological process;response to stimulus","cell surface;extracellular;membrane;organelle lumen","protein binding;signal transducer activity","Pf00054, Pf02210","1464","ENSG00000173546.7","CSPG4","15","","A tetrasaccharide linker sequence is required for GAG synthesis; Dermatan sulfate biosynthesis; Defective CHSY1 causes TPBS; Defective B4GALT7 causes EDS, progeroid type; Defective B3GALT6 causes EDSP2 and SEMDJL1; CS/DS degradation; Defective CHST14 causes EDS, musculocontractural type; Defective CHST3 causes SEDCJD; Chondroitin sulfate biosynthesis; Defective B3GAT3 causes JDSSDHD","Spinal Cord Injury",19,0,1.294,0.37,2.90260402964204e-05,0.00200088996028755,103.6,110.8,85.6,"",8,7.2,6271.7,"","",6681.9,7108.5,6728.8,5856.6,4765,5651.4,5067.2,5298.2,318.2,"","",5332.2,5380.4,5343.3,4241.6,3431.9,5651.4,4129.8,4227.8,"High","High","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q16877","6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4 OS=Homo sapiens OX=9606 GN=PFKFB4 PE=2 SV=6",0,8.798,8,4,5,1,469,54,6.62,12.21,4,"metabolic process;regulation of biological process","cytosol","catalytic activity;nucleotide binding","Pf00300, Pf01591, Pf13207, Pf13671","5210","ENSG00000114268.11","PFKFB4","3","AMPK signaling pathway; Fructose and mannose metabolism","Glycolysis","Focal Adhesion-PI3K-Akt-mTOR-signaling pathway",7,0,1.557,0.64,2.96871135525567E-5,2.03163116224888E-3,115.6,112.3,72.1,"",14.24,9.41,78.8,"","",85.6,69.6,84.2,63.8,54.1,46.5,52,44.2,4,"","",68.3,52.7,66.9,46.2,39,46.5,42.4,35.3,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q99715","Collagen alpha-1(XII) chain OS=Homo sapiens OX=9606 GN=COL12A1 PE=1 SV=2",0,105.234,12,34,34,34,3063,332.9,5.53,96.27,34,"cell differentiation;cell organization and biogenesis;metabolic process","extracellular;organelle lumen","protein binding;structural molecule activity","Pf00041, Pf00092, Pf13519","1303","ENSG00000111799.20","COL12A1","6","Protein digestion and absorption","Collagen degradation; Assembly of collagen fibrils and other multimeric structures; Collagen chain trimerization","",8,0,0.766,-0.38,3.11713460550145e-05,0.00211785749743566,88.3,91.9,119.9,"",2.3,2.21,2351.4,"","",2409.3,2527.3,2480.4,2414,3207.5,3180.4,3311.5,3147.1,119.3,"","",1922.6,1912.9,1969.7,1748.3,2310.1,3180.4,2698.9,2511.3,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q99519","Sialidase-1 OS=Homo sapiens OX=9606 GN=NEU1 PE=1 SV=1",0,29.259,15,5,6,5,415,45.4,5.88,17.77,5,"metabolic process;transport","extracellular;membrane;organelle lumen;vacuole","catalytic activity;protein binding","Pf13088, Pf13859","4758","ENSG00000234343.6; ENSG00000227129.6; ENSG00000223957.6; ENSG00000234846.7; ENSG00000184494.8; ENSG00000227315.7; ENSG00000204386.10; ENSG00000228691.6","NEU1","6; CHR_HSCHR6_MHC_DBB_CTG1; CHR_HSCHR6_MHC_MCF_CTG1; CHR_HSCHR6_MHC_MANN_CTG1; CHR_HSCHR6_MHC_SSTO_CTG1; CHR_HSCHR6_MHC_QBL_CTG1; CHR_HSCHR6_MHC_COX_CTG1; CHR_HSCHR6_MHC_APD_CTG1","Lysosome; Sphingolipid metabolism; Other glycan degradation","Sialic acid metabolism; Neutrophil degranulation; Defective NEU1 causes sialidosis; Glycosphingolipid metabolism","Regulation of toll-like receptor signaling pathway",21,0,1.378,0.46,3.415179482813e-05,0.00230265952920732,117,106,76.9,"",10.99,7,1385.6,"","",1290,1222.1,1301.4,1015.3,887.6,1014.4,935.1,869.1,70.3,"","",1029.4,925,1033.4,735.3,639.3,1014.4,762.1,693.5,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q8N8R3","Mitochondrial basic amino acids transporter OS=Homo sapiens OX=9606 GN=SLC25A29 PE=1 SV=2",0,8.572,9,3,3,3,303,32,8.75,7.09,3,"transport","membrane;mitochondrion","transporter activity","Pf00153","123096","ENSG00000197119.12","SLC25A29","14","","Amino acid transport across the plasma membrane","",4,0,0.635,-0.65,3.62029559508592e-05,0.0023909140979015,75,87.4,137.6,"",19.42,9.15,59.1,"","",70.4,67.4,65.4,96.5,123,114.7,102.6,102.1,3,"","",56.2,51,51.9,69.9,88.6,114.7,83.6,81.5,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q9H3S4","Thiamin pyrophosphokinase 1 OS=Homo sapiens OX=9606 GN=TPK1 PE=1 SV=1",0,7.694,7,1,1,1,243,27.2,5.2,4.99,1,"metabolic process","cytosol","catalytic activity;nucleotide binding","Pf04263, Pf04265","27010","ENSG00000196511.14","TPK1","7","Thiamine metabolism; Metabolic pathways","Vitamin B1 (thiamin) metabolism","",6,0,1.514,0.6,3.65657256995444e-05,0.00240645793384319,123.2,106.5,70.3,"",2.96,7.87,112.3,"","",102.4,96.6,96,97.8,63.3,64.4,63.9,74.3,5.7,"","",81.7,73.1,76.2,70.8,45.6,64.4,52.1,59.3,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P14316","Interferon regulatory factor 2 OS=Homo sapiens OX=9606 GN=IRF2 PE=1 SV=2",0,7.578,8,3,3,3,349,39.3,7.52,7.47,3,"cell proliferation;coagulation;defense response;metabolic process;regulation of biological process;response to stimulus","cytosol;nucleus","catalytic activity;DNA binding;protein binding","Pf00605, Pf01126","3660","ENSG00000168310.10","IRF2","4","","Interferon alpha/beta signaling; Interferon gamma signaling; Factors involved in megakaryocyte development and platelet production; TRAF6 mediated IRF7 activation","Apoptosis; Type II interferon signaling (IFNG)",12,0,0.685,-0.54,3.69721358799424E-5,2.41636575259637E-3,99.1,81.7,119.2,"",22.78,15.21,335.1,"","",257.3,234.4,296.3,386.2,370.6,318.4,437.8,444.4,17,"","",205.3,177.4,235.3,279.7,266.9,318.4,356.8,354.6,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P22003","Bone morphogenetic protein 5 OS=Homo sapiens OX=9606 GN=BMP5 PE=2 SV=1",1E-3,4.284,4,2,2,2,454,51.7,8.88,5.21,2,"cell differentiation;development;regulation of biological process;response to stimulus","extracellular","protein binding","Pf00019, Pf00688","653","ENSG00000112175.7","BMP5","6","Hippo signaling pathway; TGF-beta signaling pathway","","",2,0,0.661,-0.6,3.83151579594898e-05,0.0024869302527108,82.3,86.7,131,"",3.58,3.95,153.7,"","",156.1,164,159.8,169.7,247,226.6,244.9,244.6,7.8,"","",124.6,124.1,126.9,122.9,177.9,226.6,199.6,195.2,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q8N9Q2","Protein SREK1IP1 OS=Homo sapiens OX=9606 GN=SREK1IP1 PE=1 SV=1",1E-3,4.327,10,2,3,2,155,18.2,9.85,4.57,2,"metabolic process","","metal ion binding;protein binding","Pf13917","285672","ENSG00000153006.15","SREK1IP1","5","","","",0,0,0.666,-0.59,4.20029944996347e-05,0.00271696082229144,77.6,88.9,133.5,"",44.14,20.12,134,"","",152.1,154.8,152.4,326.5,213.4,160.1,249,257.5,6.8,"","",121.4,117.2,121,236.5,153.7,160.1,202.9,205.5,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P01130","Low-density lipoprotein receptor OS=Homo sapiens OX=9606 GN=LDLR PE=1 SV=1",0,77.119,25,19,30,18,860,95.3,5.05,84.96,19,"cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus;transport","cell surface;endosome;Golgi;membrane;vacuole","metal ion binding;protein binding;receptor activity","Pf00057, Pf00058, Pf06247, Pf07645, Pf12662, Pf14670","3949","ENSG00000130164.13","LDLR","19","Toxoplasmosis; Endocytosis; Hepatitis C; Bile secretion; Aldosterone synthesis and secretion; Ovarian steroidogenesis","Signaling by GPCR; Cargo recognition for clathrin-mediated endocytosis; Retinoid metabolism and transport; LDL clearance; Chylomicron clearance","Selenium Micronutrient Network; Vitamin B12 Metabolism; Folate Metabolism; Sterol Regulatory Element-Binding Proteins (SREBP) signalling; SREBF and miR33 in cholesterol and lipid homeostasis; Oncostatin M Signaling Pathway; Proprotein convertase subtilisin/kexin type 9 (PCSK9) mediated LDL receptor degradation; Evolocumab Mechanism; Composition of Lipid Particles; Wnt Signaling Pathway and Pluripotency; Wnt Signaling Pathway; Statin Pathway; DNA Damage Response (only ATM dependent)",35,1,1.33,0.41,4.42807687521807e-05,0.00281607798044171,104.5,111.6,83.9,"",4.88,2.07,3463,"","",3792,3603.8,3950.7,3554.5,2731.2,2801.8,2758,2863.1,175.7,"","",3026,2727.7,3137.2,2574.3,1967.1,2801.8,2247.8,2284.7,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q9NZJ7","Mitochondrial carrier homolog 1 OS=Homo sapiens OX=9606 GN=MTCH1 PE=1 SV=1",0,31.624,22,7,7,7,389,41.5,9.32,22.6,7,"cell death;cell organization and biogenesis;metabolic process;regulation of biological process;transport","membrane;mitochondrion","protein binding","Pf00153","23787","ENSG00000137409.19","MTCH1","6","","","",0,0,1.367,0.45,4.58036685115903e-05,0.00289344378209672,114.5,107.2,78.4,"",4.86,1.45,1015.1,"","",929.8,974.4,970.8,876.6,678.7,693.6,696.2,702.3,51.5,"","",742,737.5,770.9,634.9,488.8,693.6,567.4,560.4,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q969P0","Immunoglobulin superfamily member 8 OS=Homo sapiens OX=9606 GN=IGSF8 PE=1 SV=1",0,13.423,6,2,2,2,613,65,8,7.61,2,"cell proliferation;cellular component movement","membrane","protein binding","Pf07686","93185","ENSG00000162729.13","IGSF8","1","","","",0,0,1.648,0.72,4.65553059418866e-05,0.00291171065771641,107.8,119.6,72.6,"",19.49,14.86,43.4,"","",49.1,47.2,53.6,33,27.5,33.9,31,23.9,2.2,"","",39.2,35.7,42.6,23.9,19.8,33.9,25.3,19.1,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P04424","Argininosuccinate lyase OS=Homo sapiens OX=9606 GN=ASL PE=1 SV=4",0,17.204,9,4,4,4,464,51.6,6.48,9.18,4,"metabolic process;response to stimulus","cytoplasm;cytosol","catalytic activity;protein binding","Pf00206, Pf14698","435","ENSG00000126522.16","ASL","7","Arginine biosynthesis; Biosynthesis of amino acids; Alanine, aspartate and glutamate metabolism; Metabolic pathways","Urea cycle","Alanine and aspartate metabolism; Urea cycle and metabolism of amino groups",10,0,1.439,0.52,4.79545093496903e-05,0.00296972056589164,102.6,116.4,80.9,"",3.66,5.87,283.8,"","",322.7,330.2,321.4,302.7,240.8,211.9,231,216.8,14.4,"","",257.5,249.9,255.2,219.2,173.4,211.9,188.3,173,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P81605","Dermcidin OS=Homo sapiens OX=9606 GN=DCD PE=1 SV=2",1E-3,4.98,26,3,3,3,110,11.3,6.54,3.51,3,"defense response;metabolic process;response to stimulus","extracellular","catalytic activity;protein binding;RNA binding","Pf15291","117159","ENSG00000161634.11","DCD","12","","Antimicrobial peptides","",3,0,1.539,0.62,5.38778597263256e-05,3.30404225490532E-3,113.1,113.3,73.6,"",13.43,17.08,82.8,"","",78.4,87.6,95.7,70,50.7,63.5,42.2,57.3,4.2,"","",62.6,66.3,76,50.7,36.5,63.5,34.4,45.7,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q13309","S-phase kinase-associated protein 2 OS=Homo sapiens OX=9606 GN=SKP2 PE=1 SV=2",0,14.409,16,6,8,6,424,47.7,7.11,20.55,6,"cell communication;cell proliferation;metabolic process;regulation of biological process;response to stimulus","cytoplasm;cytosol;nucleus","catalytic activity;protein binding","Pf00646, Pf12937","6502","ENSG00000145604.15","SKP2","5","Herpes simplex infection; Pathways in cancer; FoxO signaling pathway; Small cell lung cancer; Epstein-Barr virus infection; Viral carcinogenesis; Cell cycle; mTOR signaling pathway; Ubiquitin mediated proteolysis","Regulation of RUNX2 expression and activity; Ub-specific processing proteases; Cyclin D associated events in G1; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Antigen processing: Ubiquitination & Proteasome degradation; Neddylation; SCF(Skp2)-mediated degradation of p27/p21","Cell Cycle; Retinoblastoma (RB) in Cancer; Imatinib and Chronic Myeloid Leukemia",39,0,0.75,-0.42,5.56477318605086e-05,0.00339056244961706,95.4,87.7,117,"",1.77,1.89,1021,"","",938,947.3,909.6,939.3,1268.1,1224.2,1272.6,1236.6,51.8,"","",748.5,717,722.3,680.3,913.3,1224.2,1037.2,986.8,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P23219","Prostaglandin G/H synthase 1 OS=Homo sapiens OX=9606 GN=PTGS1 PE=1 SV=2",0,37.196,17,9,10,9,599,68.6,7.23,28.98,9,"defense response;metabolic process;regulation of biological process;response to stimulus","cytoplasm;endoplasmic reticulum;Golgi;membrane;nucleus","antioxidant activity;catalytic activity;metal ion binding;protein binding","Pf00008, Pf03098, Pf07974","5742","ENSG00000095303.14","PTGS1","9","Regulation of lipolysis in adipocytes; Arachidonic acid metabolism; Platelet activation; Metabolic pathways; Serotonergic synapse","COX reactions; Synthesis of Prostaglandins (PG) and Thromboxanes (TX)","Selenium Micronutrient Network; Eicosanoid Synthesis; Overview of nanoparticle effects; Prostaglandin Synthesis and Regulation",17,0,1.365,0.45,5.70970192868003e-05,0.00340204574223686,113.5,107.6,78.9,"",6.37,12.9,1135.3,"","",1002.1,1111.2,1043.2,1155.8,672,894.2,735.2,846.4,57.6,"","",799.7,841.1,828.4,837.1,484,894.2,599.2,675.4,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q96C24","Synaptotagmin-like protein 4 OS=Homo sapiens OX=9606 GN=SYTL4 PE=1 SV=2",0,33.884,14,9,10,9,671,76,8.98,32.14,9,"cell organization and biogenesis;regulation of biological process;transport","cytosol;endosome;membrane","metal ion binding;protein binding","Pf00168, Pf02318, Pf02891","94121","ENSG00000102362.15","SYTL4","X","","Platelet degranulation","Deregulation of Rab and Rab Effector Genes in Bladder Cancer",5,0,1.347,0.43,5.69110836050601e-05,0.00340204574223686,108.8,109.7,81.5,"",5.63,5.78,1888.2,"","",1920.7,1887,1975.8,1729.4,1400.7,1573.3,1396.4,1426.2,95.8,"","",1532.7,1428.3,1569,1252.5,1008.8,1573.3,1138.1,1138.1,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q9Y2W6","Tudor and KH domain-containing protein OS=Homo sapiens OX=9606 GN=TDRKH PE=1 SV=2",0,13.884,6,3,3,3,561,62,5.02,9.67,3,"cell differentiation;cell organization and biogenesis;metabolic process;regulation of biological process","cytoplasm;mitochondrion","RNA binding","Pf00013, Pf00567, Pf07650, Pf13014","11022","ENSG00000182134.15","TDRKH","1","","PIWI-interacting RNA (piRNA) biogenesis","",3,0,0.589,-0.76,5.91622752701415E-5,0.00348117462711038,"",111.2,188.8,"",16.97,11.83,"","","",22.6,24.3,31.4,22.2,40,43.4,39.5,32.5,"","","",18,18.4,24.9,16.1,28.8,43.4,32.2,25.9,"Not Found","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P25786","Proteasome subunit alpha type-1 OS=Homo sapiens OX=9606 GN=PSMA1 PE=1 SV=1",0,106.256,55,15,57,15,263,29.5,6.61,170.94,15,"metabolic process;regulation of biological process;response to stimulus;transport","cytoplasm;cytosol;nucleus;proteasome","catalytic activity;protein binding;RNA binding","Pf00227, Pf10584","5682","ENSG00000129084.17","PSMA1","11","Proteasome","Regulation of RAS by GAPs; CDT1 association with the CDC6:ORC:origin complex; Downstream TCR signaling; UCH proteinases; NIK-->noncanonical NF-kB signaling; Hh mutants that don't undergo autocatalytic processing are degraded by ERAD; SCF-beta-TrCP mediated degradation of Emi1; Cross-presentation of soluble exogenous antigens (endosomes); Separation of Sister Chromatids; Vpu mediated degradation of CD4; Hedgehog ligand biogenesis; Regulation of RUNX2 expression and activity; Ub-specific processing proteases; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; ER-Phagosome pathway; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; ABC-family proteins mediated transport; Regulation of activated PAK-2p34 by proteasome mediated degradation; CDK-mediated phosphorylation and removal of Cdc6; FCERI mediated NF-kB activation; Neddylation; Autodegradation of the E3 ubiquitin ligase COP1; G2/M Checkpoints; Regulation of RUNX3 expression and activity; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Regulation of expression of SLITs and ROBOs; Removal of licensing factors from origins; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; Regulation of PTEN stability and activity; Regulation of DNA replication; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; Vif-mediated degradation of APOBEC3G; Antigen processing: Ubiquitination & Proteasome degradation; GLI3 is processed to GLI3R by the proteasome; SCF(Skp2)-mediated degradation of p27/p21; APC/C:Cdc20 mediated degradation of Securin; Interleukin-1 family signaling; AUF1 (hnRNP D0) binds and destabilizes mRNA; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; The role of GTSE1 in G2/M progression after G2 checkpoint; Regulation of ornithine decarboxylase (ODC); Interleukin-20 family signaling; Hedgehog 'on' state; Ubiquitin-dependent degradation of Cyclin D1; Degradation of DVL; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Degradation of AXIN; Autodegradation of Cdh1 by Cdh1:APC/C; Asymmetric localization of PCP proteins; Orc1 removal from chromatin; M/G1 Transition; Activation of NF-kappaB in B cells; Degradation of beta-catenin by the destruction complex; MAPK6/MAPK4 signaling; Dectin-1 mediated noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosis","Proteasome Degradation",150,0,0.782,-0.35,6.00256697860235e-05,0.00351010789758022,87.4,93.3,119.3,"",6.49,2.3,6039.1,"","",6539.1,6368.2,5677.7,6525.2,8275.7,8211.9,8355.5,7922.6,306.4,"","",5218.2,4820.1,4508.6,4725.8,5960.4,8211.9,6809.8,6322,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q92791","Endoplasmic reticulum protein SC65 OS=Homo sapiens OX=9606 GN=P3H4 PE=1 SV=1",0,13.421,12,5,5,5,437,50.3,4.77,14.4,5,"cell organization and biogenesis;metabolic process","chromosome;endoplasmic reticulum","protein binding","","10609","ENSG00000141696.12","LEPREL4; P3H4","17","","","",0,0,1.469,0.55,6.174966439354e-05,3.59977673168267E-3,122.9,105.4,71.8,"",11.04,7.99,254.3,"","",227.9,220.1,216.1,176,152.5,159.9,144.7,132.3,12.9,"","",181.9,166.6,171.6,127.5,109.8,159.9,117.9,105.6,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q69YH5","Cell division cycle-associated protein 2 OS=Homo sapiens OX=9606 GN=CDCA2 PE=1 SV=2",0,100.463,30,22,28,22,1023,112.6,8.4,95.06,22,"cell division;regulation of biological process","chromosome;cytosol;nucleus","","Pf15276","157313","ENSG00000184661.13","CDCA2","8","","","",0,0,0.763,-0.39,6.95579728062778e-05,0.00403009506246925,92,90,118,"",2.27,2.38,2286.3,"","",2222,2266,2248.2,2151.2,2850.2,2920.8,2939.5,3019.9,116,"","",1773.2,1715.1,1785.3,1558,2052.8,2920.8,2395.7,2409.8,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q96RU3-2","Isoform 2 of Formin-binding protein 1 OS=Homo sapiens OX=9606 GN=FNBP1",0,58.363,23,13,15,13,616,71.1,5.8,47.76,13,"cell organization and biogenesis;transport","cytoskeleton;cytosol;membrane;vacuole","protein binding","Pf00018, Pf00611, Pf07653, Pf08239, Pf13654, Pf14604","23048","","FNBP1","9","","","",0,0,0.758,-0.4,7.10001091432932e-05,0.00408856726066623,92.4,89.5,118.1,"",5,2.76,1352.1,"","",1314,1296.6,1307,1439.2,1716.5,1691.1,1803.2,1742.7,68.6,"","",1048.6,981.4,1037.9,1042.3,1236.3,1691.1,1469.6,1390.6,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q02952","A-kinase anchor protein 12 OS=Homo sapiens OX=9606 GN=AKAP12 PE=1 SV=4",0,89.761,16,19,20,19,1782,191.4,4.41,68.9,19,"regulation of biological process;response to stimulus;transport","cytoplasm;cytoskeleton;cytosol;membrane","protein binding","Pf03832","9590","ENSG00000131016.16","AKAP12","6","","","G Protein Signaling Pathways",1,0,1.331,0.41,7.80993081215264e-05,4.43177500711491E-3,95.4,116.8,87.8,"",6.34,7.31,1436.8,"","",1807.3,1563.2,1776.7,1739.9,1319.3,1323.4,1317.2,1520.1,72.9,"","",1442.2,1183.2,1410.9,1260.1,950.2,1323.4,1073.5,1213,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","O95994","Anterior gradient protein 2 homolog OS=Homo sapiens OX=9606 GN=AGR2 PE=1 SV=1",0,21.365,39,5,6,5,175,20,9,17.12,5,"cell differentiation;regulation of biological process;response to stimulus;transport","endoplasmic reticulum;extracellular;mitochondrion","protein binding","Pf13899","10551","ENSG00000106541.11","AGR2","7","","","",0,0,1.392,0.48,7.81332633084109e-05,4.43177500711491E-3,108.1,111.7,80.2,"",6.79,6.29,599.2,"","",610.1,628.7,644.4,550.1,446.2,479.7,443.7,411.2,30.4,"","",486.9,475.9,511.7,398.4,321.4,479.7,361.6,328.1,"High","Not Found","High","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P58107","Epiplakin OS=Homo sapiens OX=9606 GN=EPPK1 PE=1 SV=3",0,260.762,28,60,76,51,5088,555.3,5.62,214.62,60,"","","","","","","","","","","",0,0,1.273,0.35,7.93824036078306e-05,4.48076290975509E-3,106.5,108.4,85.1,"",1.64,0.88,7231.5,"","",7298,7386.3,7566.3,7322.8,5761.2,5792.8,5752.6,5864.7,366.9,"","",5823.8,5590.7,6008.4,5303.5,4149.4,5792.8,4688.4,4679.9,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q13642-1","Isoform 1 of Four and a half LIM domains protein 1 OS=Homo sapiens OX=9606 GN=FHL1",0,84.653,57,14,26,14,280,31.9,8.32,77,14,"cell differentiation;regulation of biological process","cytoplasm;cytosol;membrane;nucleus","metal ion binding;protein binding","Pf00412","2273","ENSG00000022267.16","FHL1","X","","","Notch Signaling Pathway",1,0,0.775,-0.37,8.01830719767693E-5,4.48076290975509E-3,83.9,94.4,121.8,"",7.54,4.42,2751.5,"","",3049.7,3130.5,3060.1,3557.5,3893.9,3818.1,4096.3,4200.8,139.6,"","",2433.7,2369.5,2430,2576.5,2804.5,3818.1,3338.5,3352.1,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q96IX5","ATP synthase membrane subunit DAPIT, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5MD PE=1 SV=1",0,14.376,29,1,2,1,58,6.5,9.76,12.21,1,"","membrane;mitochondrion","","Pf14960","84833","ENSG00000173915.14","USMG5","10","","","",0,0,0.593,-0.75,7.9541683295492e-05,4.48076290975509E-3,"",111.7,188.3,"",23.17,15.2,"","","",19.5,31.6,21.4,21.5,36,43.5,36.4,30,"","","",15.6,23.9,17,15.6,25.9,43.5,29.7,23.9,"Not Found","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q3YEC7","Rab-like protein 6 OS=Homo sapiens OX=9606 GN=RABL6 PE=1 SV=2",0,43.642,18,13,13,13,729,79.5,5.22,33.54,13,"regulation of biological process;response to stimulus","cytoplasm;nucleus","catalytic activity;nucleotide binding;protein binding","Pf00025, Pf00071, Pf08477","55684","ENSG00000196642.18","RABL6","9","","","",0,0,0.736,-0.44,8.50994960233109e-05,0.00471366358031758,178.1,51.7,70.2,120.85,2.23,7.32,841.6,10732.2,"",885.6,893.8,853.8,859.7,1045.9,1159.3,1210.7,1239.1,42.7,3,"",706.7,676.5,678,622.6,753.3,1159.3,986.7,988.8,"High","High","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P49748","Very long-chain specific acyl-CoA dehydrogenase, mitochondrial OS=Homo sapiens OX=9606 GN=ACADVL PE=1 SV=1",0,174.743,60,34,69,34,655,70.3,8.75,196.76,34,"cell differentiation;metabolic process;regulation of biological process;response to stimulus","cytosol;membrane;mitochondrion;nucleus;organelle lumen","catalytic activity;nucleotide binding","Pf00441, Pf02770, Pf02771, Pf08028","37","ENSG00000072778.19","ACADVL","17","Metabolic pathways; Fatty acid metabolism; Fatty acid degradation","Beta oxidation of palmitoyl-CoA to myristoyl-CoA; XBP1(S) activates chaperone genes","Fatty Acid Beta Oxidation; Mitochondrial LC-Fatty Acid Beta-Oxidation",15,0,1.271,0.35,8.96209528351566E-5,0.00484038370692465,136.6,91.5,72,53.35,5.34,1.84,11067.1,"",24474.5,11089.3,10950.3,11541.2,10139.7,8643.4,8823.3,8442.3,8699.5,561.5,"",3.1,8849.3,8288.3,9164.8,7343.6,6225.2,8823.3,6880.6,6942,"High","High","High","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P11532","Dystrophin OS=Homo sapiens OX=9606 GN=DMD PE=1 SV=3",0,58.71,4,12,13,10,3685,426.5,5.88,43.05,12,"cell organization and biogenesis;cellular component movement;cellular homeostasis;metabolic process;regulation of biological process;response to stimulus;transport","cell surface;cytoplasm;cytoskeleton;cytosol;membrane;nucleus","metal ion binding;protein binding;structural molecule activity","Pf00307, Pf00397, Pf00435, Pf00569, Pf09068, Pf09069, Pf11971, Pf12761, Pf13166","1756","","DMD","X","Arrhythmogenic right ventricular cardiomyopathy (ARVC); Dilated cardiomyopathy; Viral myocarditis; Hypertrophic cardiomyopathy (HCM)","Striated Muscle Contraction; Non-integrin membrane-ECM interactions","Arrhythmogenic Right Ventricular Cardiomyopathy; Ectoderm Differentiation; Striated Muscle Contraction",11,0,1.298,0.38,9.22563603606985e-05,0.00484038370692465,202.7,55,42.3,123.45,10.97,5.66,1553.1,"",22895.5,1652,1581.6,1770.9,1356.2,1157.1,1329.6,1246.5,1243.8,78.8,"",2.9,1318.3,1197.1,1406.3,982.2,833.4,1329.6,1015.9,992.5,"High","Not Found","High","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","O15294","UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit OS=Homo sapiens OX=9606 GN=OGT PE=1 SV=3",0,180.825,38,34,48,34,1046,116.9,6.7,153.82,34,"cell death;cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus","cytoplasm;cytosol;membrane;mitochondrion;nucleus","catalytic activity;protein binding","Pf00515, Pf04184, Pf07719, Pf13176, Pf13181, Pf13374, Pf13414, Pf13424, Pf13428, Pf13429, Pf13431, Pf13432, Pf13844, Pf14559","8473","ENSG00000147162.13","OGT","X","Other types of O-glycan biosynthesis; Insulin resistance","HATs acetylate histones; UCH proteinases","Ectoderm Differentiation",10,0,0.763,-0.39,1.01174244483193E-4,0.00520539239061879,133.5,72.1,94.4,80.25,12.27,2.19,3455.1,12520.9,"",3571.2,3529.8,3474.1,4442.6,4704.3,4538.8,4766.6,4602.9,175.3,3.5,"",2849.8,2671.7,2758.8,3217.5,3388.2,4538.8,3884.8,3673,"High","High","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q9UKS6","Protein kinase C and casein kinase substrate in neurons protein 3 OS=Homo sapiens OX=9606 GN=PACSIN3 PE=1 SV=2",0,106.786,53,18,29,18,424,48.5,6.18,108.57,18,"cell organization and biogenesis;metabolic process;regulation of biological process;transport","cytoplasm;cytosol;endosome;membrane","enzyme regulator activity;nucleotide binding;protein binding","Pf00018, Pf00611, Pf01025, Pf07653, Pf13514, Pf14604","29763","ENSG00000165912.15","PACSIN3","11","","Clathrin-mediated endocytosis","",3,0,0.778,-0.36,1.01418064366143E-4,0.00520539239061879,93.3,90.4,116.3,"",6.93,2.73,2781.1,"","",2776.6,2614.3,2790.1,2397.1,3300.3,3497.3,3500.3,3431.6,141.1,"","",2215.7,1978.8,2215.6,1736.1,2377,3497.3,2852.8,2738.3,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P16278","Beta-galactosidase OS=Homo sapiens OX=9606 GN=GLB1 PE=1 SV=2",0,50.002,17,9,15,9,677,76,6.57,42.78,9,"metabolic process;response to stimulus;transport","cytoplasm;extracellular;Golgi;organelle lumen;vacuole","catalytic activity;protein binding","Pf01301, Pf02449, Pf13364","2720","","GLB1","3","Other glycan degradation; Lysosome; Glycosaminoglycan degradation; Glycosphingolipid biosynthesis - ganglio series; Metabolic pathways; Sphingolipid metabolism; Galactose metabolism","Sialic acid metabolism; Neutrophil degranulation; MPS IV - Morquio syndrome B; Glycosphingolipid metabolism; HS-GAG degradation; Keratan sulfate degradation","Ectoderm Differentiation",32,0,1.305,0.38,1.00823239388204E-4,0.00520539239061879,106.3,109.7,84,"",4.36,5.02,3189.1,"","",3344.3,3239.4,3434.1,3101.3,2445.2,2678.2,2409.8,2600.3,161.8,"","",2668.8,2451.9,2727,2246.1,1761.1,2678.2,1964,2075,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q5BKU9","Oxidoreductase-like domain-containing protein 1 OS=Homo sapiens OX=9606 GN=OXLD1 PE=2 SV=1",0.004,3.188,7,1,1,1,147,15.8,8.22,3.57,1,"","mitochondrion","","Pf09791","339229","ENSG00000204237.4","OXLD1","17","","","",0,0,0.697,-0.52,1.00113859199835E-4,0.00520539239061879,123.6,72.4,104,"",85.94,45.22,404.1,"","",231.7,215.2,242.2,921.4,278.4,187.8,415.3,561,20.5,"","",184.9,162.9,192.3,667.3,200.5,187.8,338.5,447.7,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","O94955","Rho-related BTB domain-containing protein 3 OS=Homo sapiens OX=9606 GN=RHOBTB3 PE=1 SV=2",0,15.645,7,4,4,4,611,69.4,7.62,11.21,4,"regulation of biological process;response to stimulus;transport","cytoplasm;cytosol;Golgi;membrane","catalytic activity;nucleotide binding;protein binding","Pf00071, Pf00651","22836","ENSG00000164292.12","RHOBTB3","5","","Retrograde transport at the Trans-Golgi-Network","",4,0,0.674,-0.57,1.11969327290407E-4,0.00571588284827351,54.9,98.7,146.5,"",12.67,10.12,72.9,"","",113.5,142,121,148.4,194.1,195.2,185.5,231.5,3.7,"","",90.6,107.5,96.1,107.5,139.8,195.2,151.2,184.7,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P11137","Microtubule-associated protein 2 OS=Homo sapiens OX=9606 GN=MAP2 PE=1 SV=4",0,9.889,2,2,2,2,1827,199.4,4.91,6.98,2,"cell organization and biogenesis;regulation of biological process;response to stimulus","cytoplasm;cytoskeleton;cytosol","protein binding;structural molecule activity","Pf00418, Pf08377","4133","ENSG00000078018.19","MAP2","2","","","Melatonin metabolism and effects; MAPK Cascade; Sudden Infant Death Syndrome (SIDS) Susceptibility Pathways",3,0,0.616,-0.7,1.1812660153887E-4,0.00594102717342062,124.7,66.8,108.5,"",8.97,6.78,51.2,"","",27.7,30.1,27.2,24.2,42.9,45.4,49.8,43.7,2.6,"","",22.1,22.8,21.6,17.5,30.9,45.4,40.6,34.9,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","O14791","Apolipoprotein L1 OS=Homo sapiens OX=9606 GN=APOL1 PE=1 SV=5",1E-3,4.291,4,2,2,2,398,43.9,5.81,5.4,2,"defense response;metabolic process;response to stimulus;transport","extracellular;organelle lumen","protein binding;transporter activity","Pf05461","8542","ENSG00000100342.20","APOL1","22","African trypanosomiasis","Post-translational protein phosphorylation; Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs); Scavenging of heme from plasma","",8,0,0.63,-0.67,1.18896033013183E-4,0.00594102717342062,99.1,77.6,123.3,"",17.27,9.64,47.3,"","",26.7,39.1,35.1,40,68,55.3,61.5,56.4,2.4,"","",21.3,29.6,27.9,29,49,55.3,50.1,45,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P52735","Guanine nucleotide exchange factor VAV2 OS=Homo sapiens OX=9606 GN=VAV2 PE=1 SV=2",0,53.235,19,14,16,14,878,101.2,7.08,50.78,14,"cell organization and biogenesis;cellular component movement;regulation of biological process;response to stimulus","cytoplasm;cytosol;membrane","metal ion binding;protein binding","Pf00017, Pf00018, Pf00130, Pf00169, Pf00307, Pf00621, Pf07653, Pf11971, Pf14604","7410","ENSG00000160293.16","VAV2","9","T cell receptor signaling pathway; cAMP signaling pathway; Leukocyte transendothelial migration; Rap1 signaling pathway; Fc gamma R-mediated phagocytosis; Proteoglycans in cancer; Natural killer cell mediated cytotoxicity; Chemokine signaling pathway; B cell receptor signaling pathway; Fc epsilon RI signaling pathway; Regulation of actin cytoskeleton; Focal adhesion","G alpha (12/13) signalling events; FCERI mediated Ca+2 mobilization; Signal transduction by L1; Rho GTPase cycle; FCERI mediated MAPK activation; EPH-ephrin mediated repulsion of cells; DAP12 signaling; NRAGE signals death through JNK; GPVI-mediated activation cascade; VEGFR2 mediated vascular permeability; Regulation of actin dynamics for phagocytic cup formation; Signalling by NGF","Integrin-mediated Cell Adhesion; Prolactin Signaling Pathway; B Cell Receptor Signaling Pathway; Brain-Derived Neurotrophic Factor (BDNF) signaling pathway; Hepatitis C and Hepatocellular Carcinoma; VEGFA-VEGFR2 Signaling Pathway; Chemokine signaling pathway; Microglia Pathogen Phagocytosis Pathway; EGF/EGFR Signaling Pathway",53,0,0.763,-0.39,1.23290301283552E-4,6.10361296450815E-3,85.1,93,121.9,"",6.65,2.53,1259.5,"","",1373.8,1377.7,1327.9,1541.2,1846.8,1795.8,1737.4,1810.8,63.9,"","",1096.3,1042.8,1054.5,1116.2,1330.1,1795.8,1416,1445,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P41226","Ubiquitin-like modifier-activating enzyme 7 OS=Homo sapiens OX=9606 GN=UBA7 PE=1 SV=2",0.005,2.892,1,1,1,1,1012,111.6,6.04,3.13,1,"metabolic process;regulation of biological process;response to stimulus","cytoplasm;cytosol","catalytic activity;nucleotide binding;protein binding","Pf00899, Pf02134, Pf05237, Pf09358, Pf10585","7318","ENSG00000182179.12","UBA7","3","Parkinson's disease; Ubiquitin mediated proteolysis","Termination of translesion DNA synthesis; ISG15 antiviral mechanism; Negative regulators of DDX58/IFIH1 signaling; Antigen processing: Ubiquitination & Proteasome degradation","Proteasome Degradation; Parkinsons Disease Pathway",19,0,0.663,-0.59,0.000126754440576971,0.00617329390520792,113.5,74.3,112.1,"",22.64,13.07,110.4,"","",59.5,76.9,67.9,99.4,104.7,113.5,97.9,131.7,5.6,"","",47.5,58.2,53.9,72,75.4,113.5,79.8,105.1,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"Low","Master Protein","A6NEM1","Golgin subfamily A member 6-like protein 9 OS=Homo sapiens OX=9606 GN=GOLGA6L9 PE=2 SV=4",0.067,1.237,2,1,1,1,432,49.2,5.07,2.92,1,"","Golgi","","Pf15070","440295","ENSG00000197978.9","GOLGA6L9","15","","","",0,0,0.681,-0.55,0.00012779319763534,0.00617329390520792,100.6,80.8,118.6,"",28.02,3.35,214.8,"","",172.7,172.4,172.3,284.8,266.7,247.2,256.2,250.5,10.9,"","",137.8,130.5,136.8,206.3,192.1,247.2,208.8,199.9,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P19634","Sodium/hydrogen exchanger 1 OS=Homo sapiens OX=9606 GN=SLC9A1 PE=1 SV=2",0,25.674,10,7,9,7,815,90.7,7.21,26.12,7,"cell death;cell differentiation;cell organization and biogenesis;cellular component movement;cellular homeostasis;metabolic process;regulation of biological process;response to stimulus;transport","cell surface;cytoplasm;endoplasmic reticulum;membrane;mitochondrion","protein binding;structural molecule activity;transporter activity","Pf00999","6548","ENSG00000090020.10","SLC9A1","1","cAMP signaling pathway; Regulation of actin cytoskeleton; Bile secretion; Salivary secretion; Pancreatic secretion; Thyroid hormone signaling pathway; Cardiac muscle contraction; Gastric acid secretion; Proteoglycans in cancer; Adrenergic signaling in cardiomyocytes","Hyaluronan uptake and degradation; Sodium/Proton exchangers","Osteoclast Signaling; G Protein Signaling Pathways; Regulation of Actin Cytoskeleton",22,0,1.412,0.5,1.28428209714038E-4,0.00618814292111924,108.2,112.3,79.5,"",4.95,4.4,441.5,"","",442.6,443.5,489.1,472.9,334.8,340.6,312.1,314.4,22.4,"","",353.2,335.7,388.4,342.5,241.1,340.6,254.4,250.9,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q9UQ84","Exonuclease 1 OS=Homo sapiens OX=9606 GN=EXO1 PE=1 SV=2",0,49.082,15,10,12,10,846,94,8.31,41.41,10,"metabolic process;regulation of biological process;response to stimulus","nucleus","catalytic activity;DNA binding;metal ion binding;protein binding","Pf00752, Pf00867","9156","ENSG00000174371.16","EXO1","1","Mismatch repair","G2/M DNA damage checkpoint; Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta); Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha); Presynaptic phase of homologous DNA pairing and strand exchange; Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA); Processing of DNA double-strand break ends; HDR through Single Strand Annealing (SSA); Regulation of TP53 Activity through Phosphorylation; Resolution of D-loop Structures through Holliday Junction Intermediates","Mismatch repair",27,0,0.748,-0.42,0.000135004425683816,0.00647198881298454,83,92.8,124.1,"",7.89,9.34,668.2,"","",707.5,701.1,821.1,788.5,1082.9,1064.1,894.8,937,33.9,"","",564.6,530.7,652,571.1,779.9,1064.1,729.3,747.7,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q8IXL7-2","Isoform 2 of Methionine-R-sulfoxide reductase B3 OS=Homo sapiens OX=9606 GN=MSRB3",0,25.077,38,5,5,5,185,20,7.15,12.83,5,"metabolic process;response to stimulus","cytosol;endoplasmic reticulum;mitochondrion","catalytic activity;metal ion binding;protein binding","Pf01641","253827","ENSG00000174099.10","MSRB3","12","","","Sulindac Metabolic Pathway",1,0,0.712,-0.49,0.000138130595463082,0.00655530323393641,83.4,90.1,126.5,"",9.84,2.13,299.6,"","",342,306.1,278.8,344.1,447.4,446.8,465.6,461.5,15.2,"","",272.9,231.7,221.4,249.2,322.2,446.8,379.5,368.3,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q9BRL6","Serine/arginine-rich splicing factor 8 OS=Homo sapiens OX=9606 GN=SRSF8 PE=1 SV=1",0,23.245,14,5,9,3,282,32.3,11.72,20.93,5,"metabolic process","cytosol;nucleus","protein binding;RNA binding","Pf00076, Pf13893, Pf14259","10929","ENSG00000263465.4","SRSF8","11","Spliceosome; Herpes simplex infection","","",2,0,0.701,-0.51,0.000146929971314602,0.00671964478980679,96.1,84,119.9,"",4.18,9.57,281.9,"","",241.5,243.9,248.8,264.7,296.4,346.5,356.4,372.6,14.3,"","",192.7,184.6,197.6,191.7,213.5,346.5,290.5,297.3,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q12955-4","Isoform 2 of Ankyrin-3 OS=Homo sapiens OX=9606 GN=ANK3",0,20.208,4,6,6,6,1868,204,6.93,18.69,6,"cell organization and biogenesis;regulation of biological process;response to stimulus;transport","cell surface;cytoskeleton;cytosol;endoplasmic reticulum;Golgi;membrane;vacuole","protein binding;structural molecule activity","Pf00023, Pf00531, Pf00791, Pf12796, Pf13606, Pf13637, Pf13857","288","ENSG00000151150.21","ANK3","10","","","",0,0,1.427,0.51,0.000143882026836017,0.00671964478980679,106.7,113.6,79.6,"",3.84,0.6,344.9,"","",378.6,380.1,353.7,356.2,257.3,257.4,260.2,256.9,17.5,"","",302.1,287.7,280.9,258,185.3,257.4,212.1,205,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P17301","Integrin alpha-2 OS=Homo sapiens OX=9606 GN=ITGA2 PE=1 SV=1",0,89.663,17,16,23,16,1181,129.2,5.31,75.9,16,"cell differentiation;cell organization and biogenesis;cell proliferation;cellular component movement;coagulation;regulation of biological process;response to stimulus","cell surface;membrane;nucleus","metal ion binding;protein binding;receptor activity;signal transducer activity","Pf00092, Pf01839, Pf08441, Pf13517, Pf13519","3673","","ITGA2","5","Hypertrophic cardiomyopathy (HCM); Hematopoietic cell lineage; Regulation of actin cytoskeleton; Platelet activation; Pathways in cancer; Small cell lung cancer; Phagosome; ECM-receptor interaction; Arrhythmogenic right ventricular cardiomyopathy (ARVC); Focal adhesion; PI3K-Akt signaling pathway; Dilated cardiomyopathy; Proteoglycans in cancer","ECM proteoglycans; CHL1 interactions; Integrin cell surface interactions; Laminin interactions; MET activates PTK2 signaling; Platelet Adhesion to exposed collagen; Syndecan interactions","Integrin-mediated Cell Adhesion; Arrhythmogenic Right Ventricular Cardiomyopathy; Interleukin-11 Signaling Pathway; Focal Adhesion; TGF-beta Signaling Pathway",35,0,1.28,0.36,0.000152828198632271,0.00695570847172611,110.8,106.2,83,"",3.16,5.87,4121.3,"","",3937.3,3826.1,4129,3961.1,2943.7,3218.1,2960.1,3304.5,209.1,"","",3142,2896,3278.8,2868.8,2120.1,3218.1,2412.5,2636.9,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q9ULW0","Targeting protein for Xklp2 OS=Homo sapiens OX=9606 GN=TPX2 PE=1 SV=2",0,154.215,44,33,50,33,747,85.6,9.23,152.47,33,"cell death;cell division;cell organization and biogenesis;cell proliferation;regulation of biological process","cytoplasm;cytoskeleton;cytosol;nucleus","nucleotide binding;protein binding","Pf09041, Pf12214","22974","ENSG00000088325.15","TPX2","20","","Regulation of TP53 Activity through Phosphorylation; AURKA Activation by TPX2","Gastric Cancer Network 1",12,0,0.793,-0.33,0.000155111579755562,0.00704266230390159,109.7,84.2,106.1,24.41,1.96,3.38,6815.7,9659,"",6099.5,6152.3,6292.3,6363.9,7716.9,7541.9,7976.6,8137.2,345.8,2.7,"",4867.4,4656.7,4996.7,4609,5557.9,7541.9,6501,6493.3,"High","High","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q9H0H5","Rac GTPase-activating protein 1 OS=Homo sapiens OX=9606 GN=RACGAP1 PE=1 SV=1",0,158.562,47,25,42,25,632,71,8.88,135.04,25,"cell differentiation;cell division;cell organization and biogenesis;cell proliferation;cellular component movement;development;metabolic process;regulation of biological process;response to stimulus;transport","cytoplasm;cytoskeleton;cytosol;endosome;membrane;nucleus","catalytic activity;enzyme regulator activity;metal ion binding;nucleotide binding;protein binding","Pf00130, Pf00620, Pf07888","29127","ENSG00000161800.12","RACGAP1","12","","COPI-dependent Golgi-to-ER retrograde traffic; Kinesins; Rho GTPase cycle; MHC class II antigen presentation","Signal Transduction of S1P Receptor; Wnt Signaling Pathway and Pluripotency",16,0,0.783,-0.35,1.63943278878476E-4,0.00740803983602069,85,94.4,120.6,"",4.24,3.59,4212,"","",4696.6,4793.8,4341,4660.2,6312.6,6050.9,5821.1,5900.8,213.7,"","",3747.9,3628.4,3447.2,3375.1,4546.5,6050.9,4744.3,4708.7,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q96QE3","ATPase family AAA domain-containing protein 5 OS=Homo sapiens OX=9606 GN=ATAD5 PE=1 SV=4",0,54.917,8,12,12,12,1844,207.4,9.19,35.85,12,"regulation of biological process;response to stimulus","nucleus","nucleotide binding","Pf00004","79915","ENSG00000176208.8","ATAD5","17","","","",0,0,0.747,-0.42,1.64480364902797E-4,0.0074145707214416,89.5,90,120.5,"",1.69,1.78,841.6,"","",846.4,833.4,868,847,1132.6,1133.9,1137.4,1094.9,42.7,"","",675.4,630.8,689.3,613.4,815.7,1133.9,927,873.7,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q9HAW4","Claspin OS=Homo sapiens OX=9606 GN=CLSPN PE=1 SV=3",0,58.605,14,14,17,14,1339,151,4.82,54,14,"metabolic process;regulation of biological process;response to stimulus","Golgi;nucleus","DNA binding;protein binding","","63967","ENSG00000092853.13","CLSPN","1","","Ub-specific processing proteases; Activation of ATR in response to replication stress; Apoptotic cleavage of cellular proteins; Processing of DNA double-strand break ends","",17,0,0.778,-0.36,0.000166749735911909,0.0074457896262509,212.4,38.3,49.3,132.34,2.14,4.09,1336.3,"",40264.5,1332.3,1314.6,1301.2,1366.8,1746.4,1599.4,1738.7,1666,67.8,"",5.1,1063.2,995,1033.3,989.9,1257.8,1599.4,1417.1,1329.4,"High","Not Found","High","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q00534","Cyclin-dependent kinase 6 OS=Homo sapiens OX=9606 GN=CDK6 PE=1 SV=1",0,34.095,30,9,11,8,326,36.9,6.46,36.76,9,"cell differentiation;cell division;metabolic process;regulation of biological process;response to stimulus","cytoplasm;cytoskeleton;cytosol;nucleus","catalytic activity;nucleotide binding;protein binding","Pf00069, Pf07714","1021","ENSG00000105810.9","CDK6","7","Chronic myeloid leukemia; Viral carcinogenesis; Measles; Pathways in cancer; Pancreatic cancer; PI3K-Akt signaling pathway; Melanoma; Non-small cell lung cancer; Small cell lung cancer; MicroRNAs in cancer; p53 signaling pathway; Hepatitis B; Glioma; Breast cancer; Cell cycle","Regulation of RUNX1 Expression and Activity; Cyclin D associated events in G1; Oncogene Induced Senescence; Senescence-Associated Secretory Phenotype (SASP); Oxidative Stress Induced Senescence","miRNA Regulation of DNA Damage Response; miRNAs involved in DNA damage response; Cell Cycle; Metastatic brain tumor; Signaling Pathways in Glioblastoma; Retinoblastoma (RB) in Cancer; Wnt Signaling Pathway Netpath; G1 to S cell cycle control; DNA Damage Response",40,0,0.749,-0.42,1.68371064211303E-4,0.00748280626076023,180.7,51.1,68.2,128.26,3.94,4.79,488.8,10016.8,"",605.6,647,601.9,645.8,837.7,832.8,899.6,803.5,24.8,2.8,"",483.3,489.7,478,467.7,603.3,832.8,733.2,641.2,"High","High","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P01023","Alpha-2-macroglobulin OS=Homo sapiens OX=9606 GN=A2M PE=1 SV=3",1E-3,5.158,1,2,2,2,1474,163.2,6.46,4.78,2,"cell differentiation;cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus;transport","cytosol;extracellular;organelle lumen","enzyme regulator activity;protein binding","Pf00207, Pf01835, Pf07677, Pf07678, Pf07703, Pf10569, Pf11974, Pf13249","2","ENSG00000175899.14","A2M","12","Complement and coagulation cascades","Platelet degranulation ; Degradation of the extracellular matrix; Rho GTPase cycle; HDL assembly; Intrinsic Pathway of Fibrin Clot Formation","Complement and Coagulation Cascades",17,0,0.739,-0.44,0.000168170223282749,0.00748280626076023,107.8,81.7,110.5,"",13.44,22.99,579.5,"","",406,422.4,456.6,543.7,480.7,587.2,600.9,821.6,29.4,"","",324,319.7,362.6,393.8,346.2,587.2,489.7,655.6,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q86WU2","Probable D-lactate dehydrogenase, mitochondrial OS=Homo sapiens OX=9606 GN=LDHD PE=1 SV=1",0,5.433,2,1,1,1,507,54.8,6.65,3.57,1,"metabolic process","membrane;mitochondrion","catalytic activity;nucleotide binding;protein binding","Pf01565, Pf02913","197257","ENSG00000166816.13","LDHD","16","Pyruvate metabolism","Mitochondrial protein import; Metabolism of proteins","",3,0,1.599,0.68,0.000169360343096781,0.00749151794007492,"",184.6,115.4,"",26.5,8.3,"","","",44.4,45.8,46.5,24.3,26.5,28.1,32.1,28.3,"","","",35.4,34.7,36.9,17.6,19.1,28.1,26.2,22.6,"Not Found","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P49327","Fatty acid synthase OS=Homo sapiens OX=9606 GN=FASN PE=1 SV=3",0,622.445,39,89,215,88,2511,273.3,6.44,699.72,89,"cell differentiation;metabolic process;regulation of biological process;response to stimulus","cytoplasm;cytosol;Golgi;membrane;mitochondrion","catalytic activity;nucleotide binding;protein binding;RNA binding","Pf00106, Pf00107, Pf00108, Pf00109, Pf00698, Pf00975, Pf02801, Pf08242, Pf08659, Pf13602, Pf14765","2194","ENSG00000169710.8","FASN","17","Fatty acid biosynthesis; Metabolic pathways; Fatty acid metabolism; AMPK signaling pathway; Insulin signaling pathway","ChREBP activates metabolic gene expression; Fatty acyl-CoA biosynthesis; Vitamin B5 (pantothenate) metabolism; Activation of gene expression by SREBF (SREBP)","AMP-activated Protein Kinase (AMPK) Signaling; Sterol Regulatory Element-Binding Proteins (SREBP) signalling; SREBF and miR33 in cholesterol and lipid homeostasis; Liver X Receptor Pathway; Fatty Acid Biosynthesis; Angiopoietin Like Protein 8 Regulatory Pathway",23,1,1.259,0.33,0.000170853548967287,0.00753991082451896,106.6,107.8,85.6,29.21,5.2,5.96,32241.4,24684.2,44212.1,32717.9,32782.8,32460.7,29353.2,26540.5,25684.2,26106.9,23169.5,1635.8,6.9,5.6,26109,24813.3,25776.9,21258.8,19115.2,25684.2,21277.4,18488.7,"High","High","High","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q02809","Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1 OS=Homo sapiens OX=9606 GN=PLOD1 PE=1 SV=2",0,87.966,28,20,27,20,727,83.5,6.95,81.57,20,"metabolic process;response to stimulus","endoplasmic reticulum;membrane","catalytic activity;metal ion binding;protein binding","Pf03171","5351","ENSG00000083444.16","PLOD1","1","Lysine degradation","Collagen biosynthesis and modifying enzymes","",4,0,1.3,0.38,0.000172023031979274,7.55621169308028E-3,105.6,109.9,84.5,"",2.47,5.12,3610.8,"","",3763.4,3750.2,3863.5,3636.9,2994.7,2970.9,2681.9,2810.5,183.2,"","",3003.2,2838.5,3068,2634,2156.9,2970.9,2185.8,2242.7,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q12913","Receptor-type tyrosine-protein phosphatase eta OS=Homo sapiens OX=9606 GN=PTPRJ PE=1 SV=3",0,59.354,10,11,13,11,1337,145.9,5.58,44.87,11,"metabolic process;regulation of biological process;response to stimulus;transport","cell surface;membrane","catalytic activity;protein binding","Pf00041, Pf00102, Pf00782, Pf13350, Pf14566","5795","ENSG00000149177.12","PTPRJ","11","Adherens junction","Negative regulation of MET activity; Neutrophil degranulation; Phosphorylation of CD3 and TCR zeta chains","VEGFA-VEGFR2 Signaling Pathway",12,0,0.75,-0.42,0.000174195624062623,0.00763389082899031,74.5,96.6,128.9,"",8.26,6.83,490.8,"","",596.4,659.1,614.2,716.1,835,862.3,767.5,904.5,24.9,"","",475.9,498.9,487.7,518.6,601.4,862.3,625.5,721.8,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P28072","Proteasome subunit beta type-6 OS=Homo sapiens OX=9606 GN=PSMB6 PE=1 SV=4",0,42.058,32,7,23,7,239,25.3,4.92,50.79,7,"metabolic process;regulation of biological process;response to stimulus;transport","cytoplasm;cytosol;nucleus;proteasome","catalytic activity;protein binding","Pf00227","5694","ENSG00000142507.9","PSMB6","17","Proteasome","Regulation of RAS by GAPs; CDT1 association with the CDC6:ORC:origin complex; Downstream TCR signaling; UCH proteinases; NIK-->noncanonical NF-kB signaling; Hh mutants that don't undergo autocatalytic processing are degraded by ERAD; SCF-beta-TrCP mediated degradation of Emi1; Cross-presentation of soluble exogenous antigens (endosomes); Separation of Sister Chromatids; Vpu mediated degradation of CD4; Hedgehog ligand biogenesis; Regulation of RUNX2 expression and activity; Ub-specific processing proteases; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; ER-Phagosome pathway; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; ABC-family proteins mediated transport; Regulation of activated PAK-2p34 by proteasome mediated degradation; CDK-mediated phosphorylation and removal of Cdc6; FCERI mediated NF-kB activation; Neddylation; Autodegradation of the E3 ubiquitin ligase COP1; G2/M Checkpoints; Regulation of RUNX3 expression and activity; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Regulation of expression of SLITs and ROBOs; Removal of licensing factors from origins; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; Regulation of PTEN stability and activity; Regulation of DNA replication; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; Vif-mediated degradation of APOBEC3G; Antigen processing: Ubiquitination & Proteasome degradation; GLI3 is processed to GLI3R by the proteasome; SCF(Skp2)-mediated degradation of p27/p21; APC/C:Cdc20 mediated degradation of Securin; Interleukin-1 family signaling; AUF1 (hnRNP D0) binds and destabilizes mRNA; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; The role of GTSE1 in G2/M progression after G2 checkpoint; Regulation of ornithine decarboxylase (ODC); Interleukin-20 family signaling; Hedgehog 'on' state; Ubiquitin-dependent degradation of Cyclin D1; Degradation of DVL; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Degradation of AXIN; Autodegradation of Cdh1 by Cdh1:APC/C; Asymmetric localization of PCP proteins; Orc1 removal from chromatin; M/G1 Transition; Activation of NF-kappaB in B cells; Degradation of beta-catenin by the destruction complex; MAPK6/MAPK4 signaling; Dectin-1 mediated noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosis","Proteasome Degradation",150,0,0.787,-0.35,0.000195014464889676,0.00850677416359398,92.2,91.5,116.3,"",3.87,6.88,5002.4,"","",5038.2,5093,4894.2,4666,6400.6,6380.2,6240,5509.2,253.8,"","",4020.5,3854.9,3886.5,3379.3,4609.9,6380.2,5085.7,4396.2,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P53611","Geranylgeranyl transferase type-2 subunit beta OS=Homo sapiens OX=9606 GN=RABGGTB PE=1 SV=2",0,13.677,11,3,3,3,331,36.9,5.03,8.11,3,"metabolic process;regulation of biological process","cytosol;membrane","catalytic activity;metal ion binding;protein binding","Pf00432, Pf13243, Pf13249","5876","ENSG00000137955.15","RABGGTB","1","","TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain; RAB geranylgeranylation","",9,0,0.707,-0.5,0.000203059545899942,0.00881698552404161,99.3,83.1,117.5,"",3.29,4.9,281.9,"","",234,237.8,222.1,238.9,358.9,334.7,332.1,319.4,14.3,"","",186.7,180,176.4,173,258.5,334.7,270.7,254.9,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","O14967","Calmegin OS=Homo sapiens OX=9606 GN=CLGN PE=1 SV=1",0,12.52,9,5,5,5,610,70,4.69,14.08,5,"cell organization and biogenesis;metabolic process","endoplasmic reticulum;membrane","metal ion binding;protein binding","Pf00262","1047","ENSG00000153132.12","CLGN","4","","","",0,0,1.448,0.53,2.05502864194962E-4,0.0089026103186111,76.4,132.3,91.3,"",8.78,13.4,106.4,"","",190.6,212.7,176.7,178.3,120.1,126.3,128.2,160,5.4,"","",152.1,161,140.3,129.1,86.5,126.3,104.5,127.7,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q9Y6N5","Sulfide:quinone oxidoreductase, mitochondrial OS=Homo sapiens OX=9606 GN=SQOR PE=1 SV=1",0,97.76,43,18,28,18,450,49.9,9.11,96.51,18,"metabolic process","membrane;mitochondrion","catalytic activity","Pf07992, Pf13738","58472","ENSG00000137767.13","SQRDL; SQOR","15","Sulfur metabolism","Sulfide oxidation to sulfate","",6,0,1.293,0.37,0.00021029282479712,0.00906851797892239,162.5,77.5,60,92.36,4.45,7,4639.7,"",22106,4698.7,4969.1,4667.2,5115.4,3571.6,3909.3,3538.6,4081.6,235.4,"",2.8,3749.6,3761.1,3706.2,3704.8,2572.4,3909.3,2884,3257,"High","High","High","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q6UX53","Methyltransferase-like protein 7B OS=Homo sapiens OX=9606 GN=METTL7B PE=1 SV=2",0,20.362,13,3,6,3,244,27.8,8.38,17.05,3,"metabolic process","","catalytic activity","Pf01209, Pf01739, Pf05148, Pf08241, Pf08242, Pf12847, Pf13489, Pf13578, Pf13649, Pf13659, Pf13847","196410","ENSG00000170439.6","METTL7B","12","","","",0,0,1.386,0.47,0.000233910101506085,0.0100183537352538,108.5,111.2,80.3,"",19.2,9.88,301.6,"","",312.3,305.9,320.7,203.9,195.1,247.8,228.2,217.9,15.3,"","",249.2,231.5,254.7,147.7,140.5,247.8,186,173.9,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q03135","Caveolin-1 OS=Homo sapiens OX=9606 GN=CAV1 PE=1 SV=4",0,10.017,16,3,6,3,178,20.5,6.02,15.33,3,"cell communication;cell differentiation;cell organization and biogenesis;cellular component movement;cellular homeostasis;metabolic process;regulation of biological process;response to stimulus;transport","endoplasmic reticulum;endosome;Golgi;membrane","enzyme regulator activity;protein binding;structural molecule activity","Pf01146","857","ENSG00000105974.11","CAV1","7","Proteoglycans in cancer; Viral myocarditis; Focal adhesion; Bacterial invasion of epithelial cells; Endocytosis","Triglyceride catabolism; Basigin interactions; eNOS activation; NOSTRIN mediated eNOS trafficking; Disassembly of the destruction complex and recruitment of AXIN to the membrane; VEGFR2 mediated vascular permeability","Androgen receptor signaling pathway; Integrin-mediated Cell Adhesion; Focal Adhesion; TGF-beta Signaling Pathway; VEGFA-VEGFR2 Signaling Pathway; EGF/EGFR Signaling Pathway",30,0,0.682,-0.55,0.000237156734016697,0.0101344262264873,92.3,84.2,123.5,"",71.01,40.39,145.9,"","",110.1,126.4,140.2,400.4,172.4,126.8,221.1,326.1,7.4,"","",87.9,95.7,111.3,290,124.2,126.8,180.2,260.2,"High","Not Found","High","High","High","High","High","High","High","High","High",1,""]
[false,"Low","Master Protein","Q9HAH1","Zinc finger protein 556 OS=Homo sapiens OX=9606 GN=ZNF556 PE=2 SV=1",0.06,1.319,2,1,1,1,456,51.5,9.91,0,1,"metabolic process;regulation of biological process","nucleus","DNA binding;metal ion binding","Pf01352, Pf13465","80032","ENSG00000172000.7","ZNF556","19","","Generic Transcription Pathway","",3,0,0.667,-0.58,0.000243305041468522,0.0103736921518227,89.1,84.4,126.5,"",8.62,7.84,47.3,"","",43.7,44.3,45.3,52.3,72.5,61.3,70.4,64,2.4,"","",34.9,33.5,36,37.9,52.2,61.3,57.4,51.1,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P16422","Epithelial cell adhesion molecule OS=Homo sapiens OX=9606 GN=EPCAM PE=1 SV=2",0,23.163,21,5,6,5,314,34.9,7.46,17.71,5,"cell differentiation;cellular component movement;regulation of biological process;response to stimulus","cell surface;membrane","protein binding","Pf00086","4072","ENSG00000119888.10","EPCAM","2","","Cell surface interactions at the vascular wall","",2,0,0.711,-0.49,0.000244790298738806,0.0104135116274292,101.1,82.6,116.2,"",9.31,3.38,360.7,"","",307.1,282.9,324.5,262.1,420.6,398.6,408.5,430.7,18.3,"","",245.1,214.1,257.7,189.8,302.9,398.6,332.9,343.7,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P61964","WD repeat-containing protein 5 OS=Homo sapiens OX=9606 GN=WDR5 PE=1 SV=1",0,43.449,30,8,11,8,334,36.6,8.27,34.33,8,"cell organization and biogenesis;metabolic process;regulation of biological process","nucleus","catalytic activity;protein binding","Pf00400, Pf08662, Pf11715","11091","ENSG00000196363.9","WDR5","9","","RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function; RMTs methylate histone arginines; PKMTs methylate histone lysines; HATs acetylate histones; Activation of anterior HOX genes in hindbrain development during early embryogenesis; Neddylation","",16,0,0.791,-0.34,0.000257360485582669,0.0109236513521022,87,94.1,118.9,"",2.04,2.55,2329.7,"","",2594.5,2502.2,2538,2475.3,3223,3215.6,3155.3,3048.5,118.2,"","",2070.4,1893.9,2015.4,1792.7,2321.3,3215.6,2571.6,2432.6,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q9H3M7","Thioredoxin-interacting protein OS=Homo sapiens OX=9606 GN=TXNIP PE=1 SV=1",0,36.053,19,7,8,7,391,43.6,7.5,24.93,7,"cell differentiation;metabolic process;regulation of biological process;response to stimulus;transport","cytoplasm;cytosol;nucleus","enzyme regulator activity;protein binding","Pf00339, Pf02752","10628","ENSG00000265972.5","TXNIP; LOC101060503","1","NOD-like receptor signaling pathway","The NLRP3 inflammasome","VEGFA-VEGFR2 Signaling Pathway",7,0,1.325,0.41,0.00027356087758168,0.0114822619016951,109.9,108.4,81.8,"",12.53,7.34,892.9,"","",972.7,797.3,994.1,785.6,657,672.4,643.3,754.8,45.3,"","",776.2,603.5,789.4,569,473.2,672.4,524.3,602.3,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q92673","Sortilin-related receptor OS=Homo sapiens OX=9606 GN=SORL1 PE=1 SV=2",0,16.21,3,5,5,5,2214,248.3,5.55,15.02,5,"metabolic process;regulation of biological process;response to stimulus;transport","endoplasmic reticulum;endosome;extracellular;Golgi;membrane","protein binding;receptor activity;signal transducer activity","Pf00041, Pf00057, Pf00058, Pf12999","6653","ENSG00000137642.12","SORL1","11","","Amyloid fiber formation","",2,0,0.667,-0.58,0.00027445048786201,0.011494059456181,"",120,180,"",21.08,17.87,"","","",41.5,51.4,61.1,38.8,60.8,78.8,81.2,56.8,"","","",33.1,38.9,48.5,28.1,43.8,78.8,66.2,45.3,"Not Found","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q8WXG6","MAP kinase-activating death domain protein OS=Homo sapiens OX=9606 GN=MADD PE=1 SV=2",0,112.22,20,26,29,26,1647,183.2,6.04,92.42,26,"cell death;regulation of biological process;response to stimulus","cytoplasm;cytosol;membrane","enzyme regulator activity;protein binding","Pf02141, Pf03455, Pf03456","8567","ENSG00000110514.19","MADD","11","","","Deregulation of Rab and Rab Effector Genes in Bladder Cancer; TNF alpha Signaling Pathway",2,0,0.776,-0.37,0.000282683331984224,0.0116325114913247,90.2,91.7,118.1,"",3.2,4.34,1984.8,"","",2049.5,1986.3,2065.2,1924.8,2483.1,2627.3,2753.2,2570.9,100.7,"","",1635.5,1503.4,1640,1394,1788.4,2627.3,2243.9,2051.5,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q8NBJ5","Procollagen galactosyltransferase 1 OS=Homo sapiens OX=9606 GN=COLGALT1 PE=1 SV=1",0,102.181,33,20,34,20,622,71.6,7.31,98.05,20,"","endoplasmic reticulum;membrane;organelle lumen","catalytic activity","Pf00535, Pf01755, Pf13641","79709","ENSG00000130309.10","COLGALT1; GLT25D1","19","Lysine degradation; Other types of O-glycan biosynthesis","Collagen biosynthesis and modifying enzymes","",5,0,1.264,0.34,0.000282415691132965,0.0116325114913247,98.3,112.6,89.1,"",3.18,4.1,3551.7,"","",4057.7,4152.1,4075.3,3852.3,3216.2,3393.9,3070.9,3216.3,180.2,"","",3238.1,3142.7,3236.2,2790,2316.4,3393.9,2502.8,2566.5,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","O94808","Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 2 OS=Homo sapiens OX=9606 GN=GFPT2 PE=1 SV=3",0,24.933,10,6,7,3,682,76.9,7.37,19.98,6,"metabolic process","cytosol","catalytic activity;protein binding","Pf00310, Pf01380, Pf13230, Pf13522, Pf13537, Pf13580","9945","ENSG00000131459.12","GFPT2","5","Insulin resistance; Alanine, aspartate and glutamate metabolism; Metabolic pathways; Amino sugar and nucleotide sugar metabolism","Synthesis of UDP-N-acetyl-glucosamine","",10,0,1.415,0.5,0.000278974484426486,0.0116325114913247,109.9,111.4,78.7,"",8.05,7.56,275.9,"","",275.2,283.8,275.4,324.1,197.9,197.2,169.8,200.8,14,"","",219.6,214.8,218.7,234.7,142.5,197.2,138.4,160.2,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P07225","Vitamin K-dependent protein S OS=Homo sapiens OX=9606 GN=PROS1 PE=1 SV=1",0.004,3.075,1,1,1,1,676,75.1,5.67,2.73,1,"cellular component movement;coagulation;metabolic process;regulation of biological process;transport","cell surface;extracellular;membrane;organelle lumen","enzyme regulator activity;metal ion binding","Pf00054, Pf00594, Pf02210, Pf06247, Pf07645, Pf12662, Pf12947, Pf14670","5627","ENSG00000184500.14","PROS1","3","Complement and coagulation cascades","Platelet degranulation ; Regulation of Complement cascade; Transport of gamma-carboxylated protein precursors from the endoplasmic reticulum to the Golgi apparatus; Common Pathway of Fibrin Clot Formation; Cell surface interactions at the vascular wall; Removal of aminoterminal propeptides from gamma-carboxylated proteins; Gamma-carboxylation of protein precursors","Complement and Coagulation Cascades",20,0,1.526,0.61,0.000280022017674408,0.0116325114913247,101,120.2,78.8,"",13.1,14.14,49.3,"","",64.5,51,66.1,53.3,44,36.6,31.4,40.4,2.5,"","",51.5,38.6,52.5,38.6,31.7,36.6,25.6,32.2,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q13630","GDP-L-fucose synthase OS=Homo sapiens OX=9606 GN=TSTA3 PE=1 SV=1",0,58.029,31,9,13,9,321,35.9,6.6,49.19,9,"metabolic process","cytoplasm;cytosol","catalytic activity;protein binding","Pf01073, Pf01370, Pf02719, Pf04321","7264","ENSG00000278243.2; ENSG00000104522.15","TSTA3","8; CHR_HSCHR8_3_CTG7","Fructose and mannose metabolism; Amino sugar and nucleotide sugar metabolism; Metabolic pathways","GDP-fucose biosynthesis","",9,0,1.307,0.39,2.85142359335744E-4,0.0117081932242033,110.2,107.5,82.3,"",0.82,1.65,2122.8,"","",2074.4,2044.1,2069,2084,1631.8,1591.6,1578.6,1574.1,107.7,"","",1655.4,1547.2,1643,1509.3,1175.3,1591.6,1286.6,1256.1,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P40617","ADP-ribosylation factor-like protein 4A OS=Homo sapiens OX=9606 GN=ARL4A PE=1 SV=2",0,7.628,9,2,2,2,200,22.6,9.17,5.96,2,"cell differentiation;regulation of biological process;response to stimulus","cytoplasm;cytosol;membrane;nucleus","catalytic activity;nucleotide binding;protein binding;signal transducer activity","Pf00009, Pf00025, Pf00071, Pf00503, Pf01926, Pf08477, Pf09439","10124","ENSG00000122644.12","ARL4A","7","","","Mesodermal Commitment Pathway",1,0,0.713,-0.49,0.000291060284144162,0.0119252638761712,95.1,85.3,119.7,"",4.88,3.86,275.9,"","",258.5,255.5,233.6,239.8,352.8,342,358.3,328.1,14,"","",206.3,193.4,185.5,173.7,254.1,342,292,261.8,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q15170-2","Isoform 2 of Transcription elongation factor A protein-like 1 OS=Homo sapiens OX=9606 GN=TCEAL1",0,18.498,26,4,7,4,159,18.6,5.02,18,4,"metabolic process;regulation of biological process","nucleus","protein binding","Pf04538","9338","ENSG00000172465.13","TCEAL1","X","","","",0,0,0.715,-0.48,0.000295835420501822,0.012094674074542,111.3,78.7,110.1,"",61.24,26.07,433.6,"","",286,295.7,318,828.3,393.5,263.8,504.3,467.7,22,"","",228.2,223.8,252.5,599.9,283.4,263.8,411,373.2,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q04912","Macrophage-stimulating protein receptor OS=Homo sapiens OX=9606 GN=MST1R PE=1 SV=3",0,19.72,6,8,10,7,1400,152.1,6.55,23.9,8,"","","","","","","","","","","",0,0,1.321,0.4,0.00030781804634783,0.0125033704503609,111.4,107.4,81.3,"",9.94,4.74,678,"","",645,662.3,698.9,550,492.5,530,496.8,473.2,34.4,"","",514.7,501.3,555,398.3,354.7,530,404.9,377.6,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P32322","Pyrroline-5-carboxylate reductase 1, mitochondrial OS=Homo sapiens OX=9606 GN=PYCR1 PE=1 SV=2",0,71.027,29,7,16,6,319,33.3,7.61,56.76,7,"metabolic process;regulation of biological process;response to stimulus","mitochondrion;organelle lumen","catalytic activity;nucleotide binding;protein binding","Pf01210, Pf03807, Pf14748","5831","ENSG00000183010.16","PYCR1","17","Biosynthesis of amino acids; Arginine and proline metabolism; Metabolic pathways","Amino acid synthesis and interconversion (transamination)","Amino Acid metabolism; Urea cycle and metabolism of amino groups",8,0,1.313,0.39,3.11195399573361E-4,0.0125060823556205,99.9,113.6,86.5,"",20.06,11.41,565.7,"","",690,600.1,729.9,450.5,477.8,502.9,592.5,462.8,28.7,"","",550.6,454.2,579.6,326.3,344.1,502.9,482.9,369.3,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P32455","Guanylate-binding protein 1 OS=Homo sapiens OX=9606 GN=GBP1 PE=1 SV=2",0,63.024,21,15,21,13,592,67.9,6.32,63.04,15,"cell organization and biogenesis;defense response;regulation of biological process;response to stimulus","cytoplasm;cytosol;extracellular;Golgi;membrane","catalytic activity;nucleotide binding;protein binding","Pf02263, Pf02841, Pf05879","2633","ENSG00000117228.9","GBP1","1","NOD-like receptor signaling pathway","Interferon gamma signaling","Type II interferon signaling (IFNG)",6,2,1.32,0.4,0.000308861469372035,0.0125060823556205,110.4,107.9,81.7,"",7.12,4.86,2302.1,"","",2221.5,2277.6,2167.9,2537.7,1839.3,1671.8,1653.5,1736,116.8,"","",1772.8,1723.9,1721.5,1837.9,1324.7,1671.8,1347.6,1385.3,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q12815","Tastin OS=Homo sapiens OX=9606 GN=TROAP PE=1 SV=3",0,17.85,8,5,6,5,778,83.8,7.36,17.44,5,"","cytoplasm","protein binding","Pf11725","10024","ENSG00000135451.12","TROAP","12","","","",0,0,0.672,-0.57,0.000310410003497408,0.0125060823556205,78.3,89.1,132.6,"",8.11,5.45,63.1,"","",77.8,69.2,74.4,64.6,98.9,105.6,112.8,108,3.2,"","",62.1,52.4,59.1,46.8,71.2,105.6,91.9,86.2,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q49AG3","Zinc finger BED domain-containing protein 5 OS=Homo sapiens OX=9606 GN=ZBED5 PE=2 SV=2",0,9.762,4,3,3,3,693,78.9,8.27,9.1,3,"regulation of biological process","cytoplasm","DNA binding;metal ion binding","","58486","ENSG00000236287.7","ZBED5","11","","","",0,0,0.653,-0.61,0.0003139191360364,0.0125887572005425,109.8,75.2,115.1,"",11.82,3.85,59.1,"","",41.2,39.8,35.4,47.1,65.7,60.4,63.1,60.9,3,"","",32.9,30.1,28.1,34.1,47.3,60.4,51.4,48.6,"High","High","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P52732","Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2",0,142.241,35,38,55,38,1056,119.1,5.64,155.06,38,"cell division;cell organization and biogenesis;cellular component movement;regulation of biological process;transport","cytoplasm;cytoskeleton;cytosol;membrane","catalytic activity;motor activity;nucleotide binding;protein binding","Pf00225, Pf13931","3832","ENSG00000138160.5","KIF11","10","","COPI-dependent Golgi-to-ER retrograde traffic; Kinesins; MHC class II antigen presentation","",11,0,0.793,-0.34,0.000322973893295275,0.0128971054895585,117.6,80.6,101.7,50.14,1.47,2.93,4943.2,10374.5,"",4901.7,4928.3,4774.6,4919.1,6314,5893.7,6178.6,6212.6,250.8,2.9,"",3911.6,3730.2,3791.5,3562.6,4547.5,5893.7,5035.6,4957.5,"High","High","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q9UHX3","Adhesion G protein-coupled receptor E2 OS=Homo sapiens OX=9606 GN=ADGRE2 PE=1 SV=2",0,31.986,12,5,5,3,823,90.4,6.87,21.15,5,"cellular component movement;defense response;regulation of biological process;response to stimulus","cell surface;membrane","metal ion binding;protein binding;receptor activity;signal transducer activity","Pf00002, Pf00008, Pf01825, Pf06247, Pf07645, Pf12662, Pf12947","30817","ENSG00000127507.17","EMR2; ADGRE2","19","","Class B/2 (Secretin family receptors)","GPCRs, Other; GPCRs, Class B Secretin-like",6,0,1.319,0.4,0.000376244144478788,0.014836115659531,117.9,103.6,78.5,"",9.26,4.69,1013.1,"","",908.9,872.6,976.5,779.9,641,717.2,682.2,667.8,51.4,"","",725.3,660.5,775.4,564.8,461.7,717.2,556,532.9,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","O95067","G2/mitotic-specific cyclin-B2 OS=Homo sapiens OX=9606 GN=CCNB2 PE=1 SV=1",0,34.396,24,9,10,9,398,45.3,8.9,29.91,9,"cell division;cell organization and biogenesis;regulation of biological process","cytoskeleton;cytosol;membrane;nucleus","catalytic activity;protein binding","Pf00134, Pf02984, Pf04729","9133","ENSG00000157456.7","CCNB2","15","Oocyte meiosis; FoxO signaling pathway; HTLV-I infection; Cell cycle; p53 signaling pathway; Progesterone-mediated oocyte maturation","G2/M DNA replication checkpoint; Condensation of Prometaphase Chromosomes; Regulation of PLK1 Activity at G2/M Transition; Resolution of Sister Chromatid Cohesion; Polo-like kinase mediated events; Golgi Cisternae Pericentriolar Stack Reorganization; Activation of NIMA Kinases NEK9, NEK6, NEK7; Nuclear Pore Complex (NPC) Disassembly; The role of GTSE1 in G2/M progression after G2 checkpoint; Cyclin A/B1/B2 associated events during G2/M transition","miRNA Regulation of DNA Damage Response; Cell Cycle; Retinoblastoma (RB) in Cancer; TGF-beta Signaling Pathway; DNA Damage Response",31,0,0.776,-0.37,0.000394470489205156,0.0155224137502229,90.5,91.5,118,"",2.59,2.87,934.2,"","",953,927.5,983.9,937.4,1227,1180.9,1265,1210.3,47.4,"","",760.5,702,781.3,678.9,883.7,1180.9,1031,965.8,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q9Y320","Thioredoxin-related transmembrane protein 2 OS=Homo sapiens OX=9606 GN=TMX2 PE=1 SV=1",0,49.155,28,9,18,9,296,34,8.69,55.95,9,"cellular homeostasis;regulation of biological process","membrane","","Pf00085","51075","ENSG00000213593.9","TMX2","11","","","",0,0,1.304,0.38,0.000399266448603663,0.0156135500646501,112.5,106.1,81.4,"",9.78,4.07,2670.7,"","",2540.7,2534.7,2505,2056.6,1893.6,2020.6,1970.6,1844.3,135.5,"","",2027.5,1918.5,1989.2,1489.5,1363.8,2020.6,1606.1,1471.7,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P27144","Adenylate kinase 4, mitochondrial OS=Homo sapiens OX=9606 GN=AK4 PE=1 SV=1",0,26.233,30,7,8,7,223,25.3,8.4,23.96,7,"metabolic process;response to stimulus","mitochondrion;organelle lumen","catalytic activity;nucleotide binding","Pf00406, Pf05191, Pf13207, Pf13238, Pf13671","205","ENSG00000162433.14","AK4; LOC100507855","1","Thiamine metabolism; Metabolic pathways; Purine metabolism","Interconversion of nucleotide di- and triphosphates","",6,0,1.322,0.4,0.000398714818467205,0.0156135500646501,112.5,106.8,80.8,"",4.46,1.55,2390.8,"","",2414.1,2230.1,2310.7,2181,1715.6,1718.7,1702.9,1764,121.3,"","",1926.5,1688,1834.9,1579.6,1235.6,1718.7,1387.9,1407.6,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","B0I1T2","Unconventional myosin-Ig OS=Homo sapiens OX=9606 GN=MYO1G PE=1 SV=2",0,174.201,36,36,46,36,1018,116.4,8.73,128.26,36,"cellular component movement;regulation of biological process;response to stimulus;transport","membrane","catalytic activity;motor activity;nucleotide binding;protein binding","Pf00063, Pf06017","64005","ENSG00000136286.14","MYO1G","7","","","",0,0,1.269,0.34,0.000415976917447214,0.0161666090879485,163.2,76.5,60.3,90.91,3.21,5.77,5321.7,"",24474.5,5152,5225.5,5486.5,5474.4,4131.9,4297.7,3903.1,4471.9,270,"",3.1,4111.3,3955.2,4356.8,3964.8,2975.9,4297.7,3181.1,3568.5,"High","Not Found","High","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P06454","Prothymosin alpha OS=Homo sapiens OX=9606 GN=PTMA PE=1 SV=2",0,64.667,23,6,35,6,111,12.2,3.78,121.55,6,"cell organization and biogenesis;metabolic process","cytosol;nucleus","protein binding","","5757","ENSG00000187514.16","PTMA","2","Epstein-Barr virus infection","","",1,0,1.277,0.35,0.000448637213534608,0.0173644665763149,112.3,105.3,82.4,"",14.46,10.74,3727.1,"","",2700.5,3542.1,3445.3,3856.7,2655.1,2498.7,2820.2,3197.6,189.1,"","",2155,2681,2735.9,2793.2,1912.3,2498.7,2298.5,2551.6,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P04114","Apolipoprotein B-100 OS=Homo sapiens OX=9606 GN=APOB PE=1 SV=2",0,39.022,2,11,13,11,4563,515.3,7.05,39.13,11,"cell organization and biogenesis;cellular component movement;metabolic process;regulation of biological process;response to stimulus;transport","cytoplasm;cytosol;endoplasmic reticulum;endosome;extracellular;membrane;organelle lumen","protein binding;transporter activity","Pf01347, Pf04286, Pf06448, Pf09172, Pf12491","338","","APOB","2","Fat digestion and absorption; Vitamin digestion and absorption","Post-translational protein phosphorylation; Cargo recognition for clathrin-mediated endocytosis; Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs); LDL remodeling; Scavenging by Class H Receptors; VLDL clearance; Retinoid metabolism and transport; Chylomicron remodeling; Scavenging by Class A Receptors; LDL clearance; Platelet sensitization by LDL; Signaling by GPCR; Scavenging by Class B Receptors; Scavenging by Class F Receptors; VLDL assembly; Chylomicron assembly; Regulation of TLR by endogenous ligand; Cell surface interactions at the vascular wall; Chylomicron clearance","Selenium Micronutrient Network; Vitamin B12 Metabolism; Folate Metabolism; Statin Pathway",46,0,0.782,-0.35,4.57923789192405E-4,0.0176707418707199,159.6,61.6,78.8,111.18,21.45,11.3,1285.1,10732.2,"",1388.2,1482.8,1246.4,1999.1,2020.1,1538.2,1781.1,1888.9,65.2,3,"",1107.8,1122.3,989.8,1447.8,1454.9,1538.2,1451.6,1507.3,"High","High","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q9NYP9","Protein Mis18-alpha OS=Homo sapiens OX=9606 GN=MIS18A PE=1 SV=1",0,13.397,12,3,4,3,233,25.8,5.2,11.11,3,"cell division;cell organization and biogenesis;regulation of biological process","chromosome;cytosol;nucleus","metal ion binding;protein binding","Pf03226","54069","ENSG00000159055.3","MIS18A","21","","Deposition of new CENPA-containing nucleosomes at the centromere","",4,0,0.72,-0.47,0.000458421406006604,0.0176707418707199,85,90,125,"",10.97,9.62,203,"","",198.7,211.7,218.6,255.3,261.4,295,302.6,331.1,10.3,"","",158.6,160.2,173.6,184.9,188.3,295,246.6,264.2,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q5JSZ5","Protein PRRC2B OS=Homo sapiens OX=9606 GN=PRRC2B PE=1 SV=2",0,230.253,26,48,60,45,2229,242.8,8.34,191.08,48,"cell differentiation","","protein binding;RNA binding","Pf07001","84726","ENSG00000130723.18","PRRC2B","9","","","",0,1,0.798,-0.33,0.000462201202870327,0.0177801554375046,91.2,92.7,116.2,"",2.63,1.76,4324.3,"","",4435.4,4584.5,4324.3,4354.9,5614.2,5493.6,5526.9,5380.6,219.4,"","",3539.5,3470,3433.9,3154,4043.5,5493.6,4504.5,4293.6,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q9NYT0","Pleckstrin-2 OS=Homo sapiens OX=9606 GN=PLEK2 PE=1 SV=1",0,11.656,8,3,3,3,353,39.9,9.41,8.85,3,"cell organization and biogenesis;regulation of biological process;response to stimulus","cytoplasm;cytoskeleton;membrane","","Pf00169, Pf00610, Pf15410, Pf15413","26499","ENSG00000100558.8","PLEK2","14","","","",0,0,1.412,0.5,0.000472406646486956,0.0181358063797675,95.4,119.8,84.8,"",3.65,6.66,145.9,"","",186.2,187.7,180.2,173.1,128.4,144,131,123.4,7.4,"","",148.6,142.1,143.1,125.4,92.5,144,106.8,98.5,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q15059","Bromodomain-containing protein 3 OS=Homo sapiens OX=9606 GN=BRD3 PE=1 SV=1",0,80.551,29,20,27,14,726,79.5,9.36,75.99,20,"cell organization and biogenesis;metabolic process;regulation of biological process","nucleus","protein binding","Pf00439","8019","ENSG00000169925.16","BRD3","9","","","",0,1,0.8,-0.32,0.00049916192463173,0.0190084081299277,96.8,90.3,112.9,"",3.16,2.6,2682.5,"","",2487.2,2379.7,2565.6,2516.3,3081.1,3160.6,3092,3258.7,136.1,"","",1984.8,1801.2,2037.3,1822.4,2219.1,3160.6,2520,2600.4,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q6AZY7","Scavenger receptor class A member 3 OS=Homo sapiens OX=9606 GN=SCARA3 PE=1 SV=1",0,16.051,7,4,5,4,606,65.1,6.54,15.93,4,"regulation of biological process;response to stimulus;transport","endoplasmic reticulum;Golgi;membrane","protein binding;receptor activity","","51435","ENSG00000168077.13","SCARA3","8","","","",0,0,0.758,-0.4,0.000498577124903976,0.0190084081299277,184.4,49.8,65.7,118.92,5.88,7.14,587.4,6797.1,"",512.3,583,524.1,556,781.3,690.7,734.2,664.4,29.8,1.9,"",408.8,441.3,416.2,402.7,562.7,690.7,598.4,530.2,"High","High","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q8IZL8","Proline-, glutamic acid- and leucine-rich protein 1 OS=Homo sapiens OX=9606 GN=PELP1 PE=1 SV=2",0,94.789,14,14,24,14,1130,119.6,4.34,80.18,14,"metabolic process;regulation of biological process;response to stimulus","cytoplasm;membrane;nucleus","protein binding;RNA binding","Pf08166, Pf08167","27043","ENSG00000141456.14","PELP1","17","","Major pathway of rRNA processing in the nucleolus and cytosol; PTK6 Expression","",8,0,0.796,-0.33,0.000500196445112788,0.0190094777772442,92.9,91.8,115.3,"",0.8,2.03,2339.6,"","",2297.9,2326.3,2327.9,2293,2893.4,2912.6,2867.2,3003.9,118.7,"","",1833.7,1760.8,1848.6,1660.7,2083.9,2912.6,2336.8,2397,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P0DJ07","Protein PET100 homolog, mitochondrial OS=Homo sapiens OX=9606 GN=PET100 PE=1 SV=1",0,5.654,33,3,3,3,73,9.1,6.77,6.81,3,"cell organization and biogenesis","membrane;mitochondrion","protein binding","Pf09803","100131801","ENSG00000229833.9","PET100","19","","","",0,0,1.38,0.46,0.000518863021270688,0.0196398491899013,109.2,110.7,80.2,"",6.88,7.48,473,"","",487.6,471.7,496.2,423.8,345.7,349.3,318.9,382.6,24,"","",389.1,357,394,306.9,249,349.3,259.9,305.3,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q8N3X1","Formin-binding protein 4 OS=Homo sapiens OX=9606 GN=FNBP4 PE=1 SV=3",0,118.345,19,18,29,18,1017,110.2,4.74,99.13,18,"","","protein binding","Pf00397","23360","ENSG00000109920.12","FNBP4","11","","","",0,0,0.8,-0.32,0.000521915141559415,0.0196765133608268,157.4,63.4,79.2,98.15,9.93,8.62,2390.8,13236.4,"",2177.7,2124.8,2354.9,2636.7,2791.3,2703.3,2874.1,3271.3,121.3,3.7,"",1737.8,1608.3,1870,1909.6,2010.4,2703.3,2342.4,2610.4,"High","High","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q8N0X4","Citramalyl-CoA lyase, mitochondrial OS=Homo sapiens OX=9606 GN=CLYBL PE=1 SV=2",0,40.224,32,8,9,8,340,37.3,8.73,29.3,8,"","mitochondrion","catalytic activity;metal ion binding","Pf03328, Pf15617","171425","ENSG00000125246.15","CLYBL","13","","","",0,0,1.297,0.38,0.000531929608253767,0.0200141164157314,104.1,110.6,85.3,"",5.36,7.67,1265.4,"","",1293.5,1294.4,1394.8,1437.4,1035.1,1026.2,1036.7,1197.2,64.2,"","",1032.2,979.7,1107.6,1041,745.5,1026.2,844.9,955.3,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q9BS40","Latexin OS=Homo sapiens OX=9606 GN=LXN PE=1 SV=2",0,28.435,23,5,8,5,222,25.7,5.78,33.85,5,"defense response;regulation of biological process;response to stimulus","cytoplasm","enzyme regulator activity;protein binding","Pf06907","56925","ENSG00000079257.7","LXN","3","","","",0,0,0.755,-0.41,5.44783652276282E-4,0.0204151198733565,82.6,93.5,123.9,"",4.51,11.9,335.1,"","",397.5,384.5,374.1,357.1,438.2,471,536.2,569.8,17,"","",317.2,291,297.1,258.6,315.6,471,437,454.7,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P55145","Mesencephalic astrocyte-derived neurotrophic factor OS=Homo sapiens OX=9606 GN=MANF PE=1 SV=3",0,52.511,38,10,16,10,182,20.7,8.69,51.16,10,"cell differentiation;cell organization and biogenesis;regulation of biological process;response to stimulus;transport","cytosol;endoplasmic reticulum;extracellular;nucleus","protein binding;RNA binding","Pf10208","7873","","MANF","3","","Platelet degranulation","",4,0,1.268,0.34,0.000563736379699531,0.020960340038907,114.6,103.6,81.8,"",6.53,8.74,3396,"","",3155.9,2989.4,3268.6,2811.4,2481.9,2365.7,2547.6,2079.1,172.3,"","",2518.4,2262.7,2595.6,2036.1,1787.5,2365.7,2076.3,1659.1,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q9UBX1","Cathepsin F OS=Homo sapiens OX=9606 GN=CTSF PE=1 SV=1",0.007,2.68,4,1,1,1,484,53.3,8.22,2.67,1,"metabolic process","organelle lumen;vacuole","catalytic activity","Pf00112, Pf03051, Pf08246","8722","ENSG00000174080.10","CTSF","11","Lysosome; Apoptosis","MHC class II antigen presentation","",5,0,0.65,-0.62,0.000591465187909979,0.0219050871945954,89.7,82.9,127.4,"",14.46,13.06,35.5,"","",35.3,30.4,38.8,28.2,48.7,52.1,47.1,62.4,1.8,"","",28.2,23,30.8,20.4,35.1,52.1,38.4,49.8,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q9H1U4","Multiple epidermal growth factor-like domains protein 9 OS=Homo sapiens OX=9606 GN=MEGF9 PE=2 SV=3",0,25.597,12,5,5,5,602,62.9,5.67,21.8,5,"","membrane","","Pf00053","1955","ENSG00000106780.8","MEGF9","9","","","",0,0,0.744,-0.43,0.000597102366055591,0.0219751310360999,91.6,88.9,119.5,"",8.59,3.48,400.1,"","",354,415.9,362.7,415.3,513.3,496.3,530.3,536.4,20.3,"","",282.5,314.8,288,300.8,369.7,496.3,432.2,428,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q9NXV6","CDKN2A-interacting protein OS=Homo sapiens OX=9606 GN=CDKN2AIP PE=1 SV=3",0,158.267,41,22,33,22,580,61.1,9.01,120.82,22,"regulation of biological process;response to stimulus","nucleus","protein binding;RNA binding","Pf11952","55602","ENSG00000168564.5","CDKN2AIP","4","","","",0,0,0.787,-0.34,0.000609369505109258,0.0222626135638369,90,92.5,117.5,"",7.13,5.13,3656.2,"","",3673.3,3838.8,3607.1,4216.8,4702.1,4837.8,4652.1,5202.3,185.5,"","",2931.3,2905.6,2864.4,3054,3386.6,4837.8,3791.5,4151.3,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q15427","Splicing factor 3B subunit 4 OS=Homo sapiens OX=9606 GN=SF3B4 PE=1 SV=1",0,30.323,6,2,6,2,424,44.4,8.56,18.95,2,"metabolic process;regulation of biological process","nucleus;spliceosomal complex","protein binding;RNA binding","Pf00076, Pf13893, Pf14259","10262","ENSG00000143368.9","SF3B4","1","Spliceosome","mRNA Splicing - Major Pathway; mRNA Splicing - Minor Pathway","mRNA Processing",7,0,0.757,-0.4,0.000618312285072919,0.0225284719576183,114.1,80.1,105.8,"",45.18,24.87,839.6,"","",528.1,543.9,638.8,1226.5,699.8,542.9,866.4,982.2,42.6,"","",421.4,411.7,507.3,888.3,504,542.9,706.1,783.8,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P14384","Carboxypeptidase M OS=Homo sapiens OX=9606 GN=CPM PE=1 SV=2",0,31.66,19,6,9,6,443,50.5,7.36,28.63,6,"metabolic process","cell surface;extracellular;membrane","catalytic activity;metal ion binding","Pf00246, Pf00775, Pf04952, Pf13620, Pf13715","1368","ENSG00000135678.11","CPM","12","","Post-translational modification: synthesis of GPI-anchored proteins","",3,0,1.302,0.38,0.000634681333842924,0.0230535789108176,120.7,101.4,77.9,"",20.3,9.68,808.1,"","",685.1,673.8,772.2,462.3,436.4,524.9,549.3,518.8,41,"","",546.7,510,613.2,334.8,314.3,524.9,447.7,414,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q99650","Oncostatin-M-specific receptor subunit beta OS=Homo sapiens OX=9606 GN=OSMR PE=1 SV=1",0,10.556,3,2,2,2,979,110.4,5.82,7.91,2,"regulation of biological process;response to stimulus","membrane","protein binding;receptor activity;signal transducer activity","Pf00041, Pf09067","9180","ENSG00000145623.12","OSMR","5","Jak-STAT signaling pathway; PI3K-Akt signaling pathway; Cytokine-cytokine receptor interaction","IL-6-type cytokine receptor ligand interactions","Oncostatin M Signaling Pathway; Focal Adhesion-PI3K-Akt-mTOR-signaling pathway",10,0,1.42,0.51,0.000643719185923874,0.0232922758309007,104.5,114.7,80.8,"",10.59,5.88,80.8,"","",86.8,90.5,90.5,71.7,64.6,65.9,60.4,58,4.1,"","",69.3,68.5,71.9,51.9,46.5,65.9,49.2,46.3,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q9NX05","Constitutive coactivator of PPAR-gamma-like protein 2 OS=Homo sapiens OX=9606 GN=FAM120C PE=1 SV=3",0,57.705,12,12,15,10,1096,120.5,9.03,49.99,12,"","nucleus","RNA binding","","54954","","FAM120C","X","","","",0,0,0.77,-0.38,0.000654851341573615,0.0236497746455878,100.5,86.8,112.7,"",1.93,3.18,835.7,"","",716.4,727.8,727.2,698.2,890.4,959.1,929.4,945,42.4,"","",571.7,550.9,577.5,505.7,641.3,959.1,757.5,754.1,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P53814","Smoothelin OS=Homo sapiens OX=9606 GN=SMTN PE=1 SV=7",0,41.156,14,10,10,10,917,99,9.07,28.39,10,"","cytoplasm;cytoskeleton","protein binding;structural molecule activity","Pf00307, Pf11971, Pf12510","6525","ENSG00000183963.18","SMTN","22","","","",0,0,0.707,-0.5,0.000728744083362098,0.0261682856398162,42.9,106.4,150.6,"",3.82,4.78,76.9,"","",195.2,179.3,187.6,193.6,271.4,293.3,268,264,3.9,"","",155.8,135.7,149,140.2,195.5,293.3,218.4,210.7,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q99436","Proteasome subunit beta type-7 OS=Homo sapiens OX=9606 GN=PSMB7 PE=1 SV=1",0,35.098,22,6,35,6,277,29.9,7.68,89.38,6,"metabolic process;regulation of biological process;response to stimulus;transport","cytoplasm;cytosol;extracellular;nucleus;organelle lumen;proteasome","catalytic activity;nucleotide binding;protein binding","Pf00227, Pf12465","5695","ENSG00000136930.12","PSMB7","9","Proteasome","Regulation of RAS by GAPs; CDT1 association with the CDC6:ORC:origin complex; Downstream TCR signaling; UCH proteinases; NIK-->noncanonical NF-kB signaling; Hh mutants that don't undergo autocatalytic processing are degraded by ERAD; SCF-beta-TrCP mediated degradation of Emi1; Neutrophil degranulation; Cross-presentation of soluble exogenous antigens (endosomes); Separation of Sister Chromatids; Vpu mediated degradation of CD4; Hedgehog ligand biogenesis; Regulation of RUNX2 expression and activity; Ub-specific processing proteases; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; ER-Phagosome pathway; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; ABC-family proteins mediated transport; Regulation of activated PAK-2p34 by proteasome mediated degradation; CDK-mediated phosphorylation and removal of Cdc6; FCERI mediated NF-kB activation; Neddylation; Autodegradation of the E3 ubiquitin ligase COP1; G2/M Checkpoints; Regulation of RUNX3 expression and activity; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Regulation of expression of SLITs and ROBOs; Removal of licensing factors from origins; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; Regulation of PTEN stability and activity; Regulation of DNA replication; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; Vif-mediated degradation of APOBEC3G; Antigen processing: Ubiquitination & Proteasome degradation; GLI3 is processed to GLI3R by the proteasome; SCF(Skp2)-mediated degradation of p27/p21; APC/C:Cdc20 mediated degradation of Securin; Interleukin-1 family signaling; AUF1 (hnRNP D0) binds and destabilizes mRNA; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; The role of GTSE1 in G2/M progression after G2 checkpoint; Regulation of ornithine decarboxylase (ODC); Interleukin-20 family signaling; Hedgehog 'on' state; Ubiquitin-dependent degradation of Cyclin D1; Degradation of DVL; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Degradation of AXIN; Autodegradation of Cdh1 by Cdh1:APC/C; Asymmetric localization of PCP proteins; Orc1 removal from chromatin; M/G1 Transition; Activation of NF-kappaB in B cells; Degradation of beta-catenin by the destruction complex; MAPK6/MAPK4 signaling; Dectin-1 mediated noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosis","Proteasome Degradation",151,0,0.8,-0.32,0.000757909826810454,0.0271125015318104,93.5,91.8,114.7,"",3.71,1.45,3449.2,"","",3334.9,3440.9,3225.3,3512.4,4273.8,4282.1,4192.7,4157,175,"","",2661.3,2604.4,2561.2,2543.8,3078.1,4282.1,3417.1,3317.2,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q969Z0","FAST kinase domain-containing protein 4 OS=Homo sapiens OX=9606 GN=TBRG4 PE=1 SV=1",0,38.954,20,11,15,11,631,70.7,7.42,40.51,11,"metabolic process;regulation of biological process","mitochondrion","catalytic activity;protein binding;RNA binding","Pf06743, Pf08368, Pf08373","9238","ENSG00000136270.13","TBRG4","7","","","",0,0,0.797,-0.33,0.000764504134709076,0.0272966996150946,123.5,78.3,98.2,60.72,27.62,12.45,3427.5,8585.8,"",3295.7,3100.7,3586.6,5416.4,4298.5,3382.2,4540.3,4330.3,173.9,2.4,"",2630,2346.9,2848.1,3922.8,3095.9,3382.2,3700.4,3455.5,"High","High","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q96HD1","Protein disulfide isomerase CRELD1 OS=Homo sapiens OX=9606 GN=CRELD1 PE=1 SV=3",0,48.024,24,9,10,9,420,45.4,4.87,37.37,9,"","membrane","metal ion binding","Pf07645, Pf11938","78987","ENSG00000163703.17","CRELD1","3","","","",0,0,1.323,0.4,0.000776583077408466,0.0275198896174317,92.3,118.3,89.4,"",13.13,4.1,445.4,"","",598.5,545.4,602.4,447.8,448.6,422.8,440.9,409.5,22.6,"","",477.6,412.8,478.4,324.3,323.1,422.8,359.3,326.8,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","O94766","Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 3 OS=Homo sapiens OX=9606 GN=B3GAT3 PE=1 SV=2",0,14.667,11,5,8,5,335,37.1,8.27,24.77,5,"metabolic process;regulation of biological process","Golgi;membrane","catalytic activity;enzyme regulator activity;metal ion binding;protein binding","Pf03360","26229","ENSG00000149541.9","B3GAT3","11","Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate; Glycosaminoglycan biosynthesis - heparan sulfate / heparin; Metabolic pathways","A tetrasaccharide linker sequence is required for GAG synthesis; Defective B3GAT3 causes JDSSDHD","",13,0,1.292,0.37,0.000776025031327343,0.0275198896174317,106.3,109.2,84.5,"",13.15,3.65,786.4,"","",822.9,797.2,817.8,613.2,624.2,597.2,653,625.7,39.9,"","",656.7,603.4,649.4,444.1,449.6,597.2,532.2,499.3,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P09619","Platelet-derived growth factor receptor beta OS=Homo sapiens OX=9606 GN=PDGFRB PE=1 SV=1",0.003,3.472,1,2,2,1,1106,123.9,4.98,4.03,2,"cell organization and biogenesis;cell proliferation;cellular component movement;development;metabolic process;regulation of biological process;response to stimulus","cell surface;cytoplasm;membrane;nucleus;organelle lumen;vacuole","catalytic activity;nucleotide binding;protein binding;receptor activity;signal transducer activity;structural molecule activity","Pf00047, Pf00069, Pf07679, Pf07714, Pf13895, Pf13927","5159","ENSG00000113721.13","PDGFRB","5","Cytokine-cytokine receptor interaction; Regulation of actin cytoskeleton; Melanoma; Pathways in cancer; MicroRNAs in cancer; Calcium signaling pathway; Focal adhesion; Glioma; Rap1 signaling pathway; EGFR tyrosine kinase inhibitor resistance; Phospholipase D signaling pathway; PI3K-Akt signaling pathway; Gap junction; Central carbon metabolism in cancer; Ras signaling pathway; Prostate cancer; Choline metabolism in cancer; MAPK signaling pathway; HTLV-I infection","PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling; Constitutive Signaling by Aberrant PI3K in Cancer; RAF/MAP kinase cascade; Downstream signal transduction; Interleukin-20 family signaling","Signaling Pathways in Glioblastoma; PDGF Pathway; Focal Adhesion; Osteoblast Signaling; Imatinib and Chronic Myeloid Leukemia; MAPK Signaling Pathway; ESC Pluripotency Pathways; Focal Adhesion-PI3K-Akt-mTOR-signaling pathway; Regulation of Actin Cytoskeleton",47,0,0.722,-0.47,0.000781161510410522,0.0276302970199137,103.6,82.4,114,"",6.52,12.39,260.2,"","",205.5,233.8,205,208.1,312.5,291.2,281.6,231,13.2,"","",164,177,162.8,150.7,225.1,291.2,229.5,184.3,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q6UWJ1","Transmembrane and coiled-coil domain-containing protein 3 OS=Homo sapiens OX=9606 GN=TMCO3 PE=1 SV=1",2E-3,3.825,2,2,2,2,677,75.5,6.9,4.59,2,"transport","extracellular;membrane","transporter activity","Pf00999, Pf03879, Pf07464, Pf09403","55002","ENSG00000150403.17","TMCO3","13","","","",0,0,0.72,-0.47,0.000792836705944211,0.027886591623602,105.5,81.4,113,"",31.4,29.96,183.3,"","",145.6,137.4,169.4,72.9,116.4,189.2,255,203.8,9.3,"","",116.2,104,134.5,52.8,83.8,189.2,207.8,162.6,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q12797","Aspartyl/asparaginyl beta-hydroxylase OS=Homo sapiens OX=9606 GN=ASPH PE=1 SV=3",0,129.752,34,25,57,25,758,85.8,5.01,179.71,25,"metabolic process;regulation of biological process;response to stimulus;transport","cytoplasm;endoplasmic reticulum;membrane;organelle lumen","catalytic activity;metal ion binding;protein binding;structural molecule activity","Pf05118, Pf05279, Pf13414, Pf13428, Pf13432, Pf14559","444","ENSG00000198363.17","ASPH","8","","Ion homeostasis; Stimuli-sensing channels","",6,0,1.244,0.32,0.000811052136443946,0.0284214336793196,151.8,82.1,66,81.57,4.91,2.73,5721.8,"",21316.5,6064.6,5885.8,6176.3,5513.9,4702.1,4902.4,4686.8,4938.1,290.3,"",2.7,4839.6,4455,4904.6,3993.4,3386.6,4902.4,3819.8,3940.5,"High","Not Found","High","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q8TER5","Rho guanine nucleotide exchange factor 40 OS=Homo sapiens OX=9606 GN=ARHGEF40 PE=1 SV=3",0,50.594,9,12,13,12,1519,164.6,6.15,37.56,12,"regulation of biological process","cytoplasm","protein binding","Pf00169, Pf00621","55701","ENSG00000165801.9","ARHGEF40","14","","G alpha (12/13) signalling events; NRAGE signals death through JNK; Signalling by NGF; Rho GTPase cycle","",11,0,1.368,0.45,8.77017326154084E-4,0.0304505574566146,96.6,117.5,85.9,"",13.04,8.38,222.7,"","",267.8,274.3,291.8,212.8,222.3,203.1,193.2,182.8,11.3,"","",213.7,207.6,231.7,154.1,160.1,203.1,157.5,145.9,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P10586","Receptor-type tyrosine-protein phosphatase F OS=Homo sapiens OX=9606 GN=PTPRF PE=1 SV=2",0,287.147,38,54,70,48,1907,212.7,6.3,235.23,54,"cell organization and biogenesis;cellular component movement;metabolic process;regulation of biological process;response to stimulus","membrane","catalytic activity;protein binding;receptor activity;signal transducer activity","Pf00041, Pf00047, Pf00102, Pf07679, Pf13895, Pf13927, Pf14566","5792","ENSG00000142949.16","PTPRF","1","Adherens junction; Insulin signaling pathway; Insulin resistance; Cell adhesion molecules (CAMs)","Receptor-type tyrosine-protein phosphatases; Synaptic adhesion-like molecules","Brain-Derived Neurotrophic Factor (BDNF) signaling pathway; Insulin Signaling",10,3,0.793,-0.33,8.89501226963629E-4,0.0307708776096869,85.7,94.8,119.5,"",3.03,2.53,3321.1,"","",3788.3,3631.8,3715.8,3530.5,4584.9,4822.3,4677.1,4563.2,168.5,"","",3023.1,2748.9,2950.7,2556.9,3302.2,4822.3,3811.9,3641.3,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","O60568","Multifunctional procollagen lysine hydroxylase and glycosyltransferase LH3 OS=Homo sapiens OX=9606 GN=PLOD3 PE=1 SV=1",0,117.946,33,22,38,22,738,84.7,6.05,114.21,22,"cell organization and biogenesis;metabolic process;response to stimulus","endoplasmic reticulum;Golgi;membrane","catalytic activity;metal ion binding;protein binding","Pf03171","8985","ENSG00000106397.11","PLOD3","7","Other types of O-glycan biosynthesis; Lysine degradation","Collagen biosynthesis and modifying enzymes","",5,0,1.239,0.31,0.000894568038603438,0.0308895815596741,124.1,97.3,78.5,40.08,8.38,4.59,5193.5,9301.3,"",5479.5,5417.9,5557.8,4610.2,4473.2,4593.2,4322.5,4127.2,263.5,2.6,"",4372.7,4100.8,4413.4,3338.9,3221.7,4593.2,3522.9,3293.4,"High","High","High","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","O15119","T-box transcription factor TBX3 OS=Homo sapiens OX=9606 GN=TBX3 PE=1 SV=4",0,53.914,19,12,16,12,743,79.3,8.16,48.99,12,"cell differentiation;development;metabolic process;regulation of biological process;response to stimulus;transport","nucleus","DNA binding;protein binding","Pf00907, Pf12598","6926","ENSG00000135111.15","TBX3","12","Signaling pathways regulating pluripotency of stem cells","","Mesodermal Commitment Pathway; Preimplantation Embryo",3,0,0.792,-0.34,0.000932652671030043,0.0319708596196288,95.1,90.5,114.4,"",1.54,0.9,2041.9,"","",1899.6,1935.5,1969.5,1952.9,2446.9,2465.4,2427.8,2478.1,103.6,"","",1515.9,1465,1564,1414.4,1762.3,2465.4,1978.7,1977.5,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P52569","Cationic amino acid transporter 2 OS=Homo sapiens OX=9606 GN=SLC7A2 PE=1 SV=2",0,29.146,11,7,11,7,658,71.6,7.28,27.83,7,"metabolic process;regulation of biological process;transport","membrane","transporter activity","Pf00324, Pf13520, Pf13906","6542","ENSG00000003989.17","SLC7A2","8","","Amino acid transport across the plasma membrane","",4,0,1.249,0.32,9.43912033378291E-4,0.0322398019646459,103.3,109.2,87.5,"",3.7,3.1,1545.3,"","",1729.3,1584,1632,1635.5,1346.9,1275.4,1341.5,1272.8,78.4,"","",1380,1198.9,1296,1184.5,970.1,1275.4,1093.3,1015.7,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q04695","Keratin, type I cytoskeletal 17 OS=Homo sapiens OX=9606 GN=KRT17 PE=1 SV=2",0,482.276,91,56,429,30,432,48.1,5.02,1201.88,56,"cell death;cell organization and biogenesis;regulation of biological process;response to stimulus","cytoplasm;cytoskeleton;cytosol","protein binding;receptor activity;signal transducer activity;structural molecule activity","Pf00038, Pf07888","3872","ENSG00000128422.15","KRT17","17","","Formation of the cornified envelope","",3,39,0.817,-0.29,9.46572581246086E-4,0.0322723157302817,86.1,96.2,117.8,18.19,10.36,3.9,37996.7,29334.8,"",36476.3,38122.2,36045.4,44728.2,44253.4,46751.3,44610.9,48024.7,1927.8,8.2,"",29108.2,28854.7,28623.5,32394,31872.5,46751.3,36358.4,38322.5,"High","High","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q07157-2","Isoform Short of Tight junction protein ZO-1 OS=Homo sapiens OX=9606 GN=TJP1",0,152.178,25,38,48,1,1668,186.9,6.79,126.06,38,"cell communication;cell organization and biogenesis;regulation of biological process;response to stimulus","cytoplasm;cytosol;membrane","protein binding","Pf00018, Pf00595, Pf00625, Pf00791, Pf07653, Pf13180","7082","ENSG00000104067.16","TJP1","15","","","",0,0,0.708,-0.5,0.000953346098016228,0.0324119694291972,103.3,81.5,115.2,"",19.63,20.7,126.1,"","",98.6,100.5,131.3,82.8,100.5,144.4,169.6,137,6.4,"","",78.7,76.1,104.3,60,72.4,144.4,138.2,109.3,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P30825","High affinity cationic amino acid transporter 1 OS=Homo sapiens OX=9606 GN=SLC7A1 PE=1 SV=1",0,10.048,4,3,3,3,629,67.6,5.43,7.87,3,"transport","membrane","protein binding;transporter activity","Pf00324, Pf13520, Pf13906","6541","ENSG00000139514.12","SLC7A1","13","MicroRNAs in cancer","Amino acid transport across the plasma membrane","",5,0,0.744,-0.43,0.000954924406173063,0.0324119694291972,109,81.5,109.5,"",56.89,24.07,496.7,"","",350.4,325.3,393.3,919,455,339.4,546.7,609.3,25.2,"","",279.6,246.2,312.3,665.6,327.7,339.4,445.6,486.2,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q9Y276","Mitochondrial chaperone BCS1 OS=Homo sapiens OX=9606 GN=BCS1L PE=1 SV=1",0,21.159,16,5,5,5,419,47.5,8.5,15.14,5,"cell organization and biogenesis;metabolic process","membrane;mitochondrion","catalytic activity;DNA binding;nucleotide binding;protein binding;RNA binding","Pf00004, Pf00910, Pf06431, Pf08740","617","ENSG00000074582.12","BCS1L","2","","Mitochondrial protein import; Metabolism of proteins","",2,0,1.305,0.38,0.000969894031539909,0.0327716609440533,104,111,85,"",15.87,5.31,575.5,"","",606.4,621.7,666.9,452.6,470.1,480.5,471,425.7,29.2,"","",483.9,470.6,529.6,327.8,338.6,480.5,383.9,339.7,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q9ULI2","Beta-citrylglutamate synthase B OS=Homo sapiens OX=9606 GN=RIMKLB PE=2 SV=2",0,60.289,35,11,14,11,386,42.4,6,47.59,11,"metabolic process","cytoplasm;cytosol","catalytic activity;metal ion binding;nucleotide binding","Pf02655, Pf08443, Pf13535","57494","ENSG00000166532.15","RIMKLB","12","Alanine, aspartate and glutamate metabolism; Metabolic pathways","Amino acid synthesis and interconversion (transamination)","",5,0,0.785,-0.35,0.000975732735229107,0.0329100712553703,94.3,90.5,115.2,"",3.33,6.36,1852.7,"","",1818,1803.9,1750.5,1688.8,2364.3,2196.5,2330.6,2052.3,94,"","",1450.8,1365.4,1390.1,1223.1,1702.8,2196.5,1899.5,1637.7,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q15149-8","Isoform 8 of Plectin OS=Homo sapiens OX=9606 GN=PLEC",0,1679.187,63,341,602,1,4525,513.4,5.76,1754.11,341,"cell organization and biogenesis","cytoplasm;cytoskeleton;cytosol;membrane","protein binding;RNA binding;structural molecule activity","Pf00307, Pf00681, Pf07812","5339","ENSG00000178209.14","PLEC","8","","","",0,0,1.492,0.58,0.000986844395368891,0.0332255203916713,"",179.6,120.4,"",7.05,10.72,"","","",54.6,50.9,54.8,47.1,34.6,36.1,31.3,40.5,"","","",43.6,38.5,43.5,34.1,24.9,36.1,25.5,32.3,"Not Found","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","O75828","Carbonyl reductase [NADPH] 3 OS=Homo sapiens OX=9606 GN=CBR3 PE=1 SV=3",0,53.309,42,10,16,8,277,30.8,6.18,54.51,10,"metabolic process","cytoplasm;cytosol","catalytic activity;nucleotide binding;protein binding","Pf00106, Pf08659, Pf13561","874","ENSG00000159231.5","CBR3","21","Metabolic pathways; Arachidonic acid metabolism; Metabolism of xenobiotics by cytochrome P450","Phase I - Functionalization of compounds","NRF2 pathway",7,0,0.771,-0.38,0.0010003610743885,0.0335014538529255,77.8,96.7,125.5,"",2.87,16.4,581.4,"","",718.7,696,728.1,745.7,1018.6,1121.3,774.6,864.3,29.5,"","",573.5,526.8,578.2,540.1,733.6,1121.3,631.3,689.7,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P02042","Hemoglobin subunit delta OS=Homo sapiens OX=9606 GN=HBD PE=1 SV=2",0,6.859,6,1,4,1,147,16,8.05,10.54,1,"coagulation;transport","cytosol","metal ion binding;protein binding;transporter activity","Pf00042","3045","ENSG00000223609.7","HBD","11","","Factors involved in megakaryocyte development and platelet production","",2,0,1.386,0.47,1.00849162428585E-3,0.0336543989390655,110.8,109.9,79.3,"",12.03,12.72,189.2,"","",196.9,157.5,208.7,178.9,127.3,151.3,113.4,144.1,9.6,"","",157.1,119.2,165.7,129.6,91.7,151.3,92.4,115,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q56NI9","N-acetyltransferase ESCO2 OS=Homo sapiens OX=9606 GN=ESCO2 PE=1 SV=1",0,74.027,29,15,21,15,601,68.3,9.39,70.31,15,"cell differentiation;metabolic process;regulation of biological process;response to stimulus","chromosome;Golgi;nucleus","catalytic activity;metal ion binding","Pf13878, Pf13880","157570","ENSG00000171320.14","ESCO2","8","","Establishment of Sister Chromatid Cohesion","",4,0,0.811,-0.3,0.00104863612283168,0.0347484896281487,152.6,66,81.4,85.41,3.08,1.94,2915.1,11805.5,"",2552.9,2524.2,2657.6,2471,3222,3097.6,3162.9,3093,147.9,3.3,"",2037.2,1910.6,2110.4,1789.6,2320.6,3097.6,2577.8,2468.1,"High","High","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q9Y4L1","Hypoxia up-regulated protein 1 OS=Homo sapiens OX=9606 GN=HYOU1 PE=1 SV=1",0,236.83,46,39,81,39,999,111.3,5.22,258.35,39,"regulation of biological process;response to stimulus;transport","endoplasmic reticulum;extracellular;membrane;organelle lumen","nucleotide binding;protein binding","Pf00012","10525","ENSG00000280682.2; ENSG00000149428.18","HYOU1","11; CHR_HG2217_PATCH","Protein processing in endoplasmic reticulum","Scavenging by Class F Receptors; XBP1(S) activates chaperone genes","",8,0,1.222,0.29,0.00106305460087275,0.0351645802124071,155.2,79.6,65.2,78.35,5.56,3.28,9202.5,17529.3,45001.6,9268.1,8896.7,9084,8147.1,7126.6,7463.6,7678.3,7255.2,466.9,4.9,5.7,7396,6733.9,7213.6,5900.5,5132.8,7463.6,6257.9,5789.5,"High","High","High","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P04264","Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6",0,199.154,48,38,93,32,644,66,8.12,301.5,38,"cell death;defense response;metabolic process;regulation of biological process;response to stimulus;transport","cytoskeleton;cytosol;extracellular;membrane;nucleus","catalytic activity;motor activity;protein binding;receptor activity;structural molecule activity","Pf00038, Pf01576, Pf05103, Pf05957, Pf12128, Pf13166, Pf13514","3848","ENSG00000167768.4","KRT1","12","","Formation of the cornified envelope; Neutrophil degranulation","Corticotropin-releasing hormone signaling pathway",7,2,1.233,0.3,0.00108475311686762,0.0357570975067986,212.5,48.3,39.2,19.95,99.48,31.27,19928.6,26472.9,"",5295.1,5153,24031.3,4125.7,2965.5,3992.5,4494.2,6280,1011.1,7.4,"",4225.5,3900.3,19083.2,2988,2135.8,3992.5,3662.8,5011.3,"High","High","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q969Q0","60S ribosomal protein L36a-like OS=Homo sapiens OX=9606 GN=RPL36AL PE=1 SV=3",0,31.732,48,7,23,1,106,12.5,10.65,57.73,7,"metabolic process","cytoplasm;cytosol;membrane;nucleus;ribosome","protein binding;structural molecule activity","Pf00935","6166","ENSG00000165502.6","RPL36AL","14","Ribosome","Peptide chain elongation; Eukaryotic Translation Termination; Viral mRNA Translation; L13a-mediated translational silencing of Ceruloplasmin expression; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); Selenocysteine synthesis; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; Regulation of expression of SLITs and ROBOs; Formation of a pool of free 40S subunits; SRP-dependent cotranslational protein targeting to membrane","",33,0,0.738,-0.44,0.00108316068907421,0.0357570975067986,115.3,78.4,106.3,"",56.35,31.89,358.7,"","",163.2,200,297.7,538.6,281.4,202.3,431.8,389,18.2,"","",130.2,151.4,236.4,390.1,202.7,202.3,351.9,310.4,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q9NR19","Acetyl-coenzyme A synthetase, cytoplasmic OS=Homo sapiens OX=9606 GN=ACSS2 PE=1 SV=1",0,49.418,15,10,12,10,701,78.5,6.46,41.36,10,"cell organization and biogenesis;metabolic process","cytoplasm;cytosol;organelle lumen","catalytic activity;nucleotide binding","Pf00501, Pf13193","55902","ENSG00000131069.19","ACSS2","20","Metabolic pathways; Pyruvate metabolism; Propanoate metabolism; Glycolysis / Gluconeogenesis; Carbon metabolism","Transcriptional activation of mitochondrial biogenesis; Ethanol oxidation","Fatty Acid Beta Oxidation; Fatty Acid Biosynthesis; Amino acid conjugation of benzoic acid",15,0,1.279,0.36,1.09286465878511E-3,0.0358991785654489,99.1,112.8,88.1,"",9.99,5.78,1653.7,"","",1909.9,1855.2,1956.1,1553.1,1499.4,1475.7,1466.9,1316.6,83.9,"","",1524.1,1404.2,1553.3,1124.8,1079.9,1475.7,1195.5,1050.6,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","O95229","ZW10 interactor OS=Homo sapiens OX=9606 GN=ZWINT PE=1 SV=2",0,26.22,25,7,10,7,277,31.3,5.15,28.73,7,"cell division;cell organization and biogenesis;regulation of biological process","chromosome;cytoplasm;cytosol;nucleus","protein binding","Pf09731, Pf12128, Pf15556","11130","ENSG00000122952.16","ZWINT","10","","Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal; Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins","",16,0,0.805,-0.31,0.00110040816470858,0.0360216800953477,87.3,94.9,117.8,"",4.16,3.76,1214.1,"","",1321.5,1350.6,1317,1225.6,1672.4,1583.9,1718,1604.1,61.6,"","",1054.6,1022.3,1045.8,887.6,1204.5,1583.9,1400.2,1280,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P27797","Calreticulin OS=Homo sapiens OX=9606 GN=CALR PE=1 SV=1",0,179.801,69,28,99,28,417,48.1,4.44,269.16,28,"cell differentiation;cell organization and biogenesis;cellular homeostasis;metabolic process;regulation of biological process;response to stimulus;transport","cell surface;cytoplasm;cytosol;endoplasmic reticulum;extracellular;Golgi;membrane;nucleus;organelle lumen","DNA binding;metal ion binding;protein binding;RNA binding","Pf00262","811","ENSG00000179218.13","CALR","19","HTLV-I infection; Antigen processing and presentation; Protein processing in endoplasmic reticulum; Phagosome; Chagas disease (American trypanosomiasis)","Scavenging by Class F Receptors; Assembly of Viral Components at the Budding Site; ATF6 (ATF6-alpha) activates chaperone genes; Antigen Presentation: Folding, assembly and peptide loading of class I MHC; ER-Phagosome pathway; Calnexin/calreticulin cycle; Scavenging by Class A Receptors","Androgen receptor signaling pathway; Photodynamic therapy-induced unfolded protein response; Calcium Regulation in the Cardiac Cell",32,0,1.221,0.29,1.10376866902206E-3,0.0360691740838906,147.4,83.9,68.7,73.37,2.27,3.94,14508.4,"",45791.1,14736,14135.1,14585.5,14906.5,11794.6,11877.9,12140.1,12849.4,736.1,"",5.8,11759.4,10698.9,11582.3,10795.9,8494.8,11877.9,9894.3,10253.5,"High","Not Found","High","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q5SGD2","Protein phosphatase 1L OS=Homo sapiens OX=9606 GN=PPM1L PE=1 SV=1",0,24.097,21,7,7,7,360,41,5.87,19.81,7,"metabolic process;regulation of biological process;response to stimulus","membrane","catalytic activity;metal ion binding","Pf00481, Pf13672","151742","ENSG00000163590.13","PPM1L","3","","Sphingolipid de novo biosynthesis","Amino Acid metabolism",5,0,1.315,0.4,0.00110758950314582,0.036069225061066,109.1,108.5,82.4,"",4.73,4.61,565.7,"","",529.3,570.7,554,592.2,402.5,436.6,418.5,446.9,28.7,"","",422.4,432,439.9,428.9,289.9,436.6,341.1,356.6,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q69YL0","Protein NCBP2AS2 OS=Homo sapiens OX=9606 GN=NCBP2AS2 PE=1 SV=1",0,9.167,35,4,4,4,99,10.9,12,8.47,4,"","","","","152217","ENSG00000270170.1","LOC152217; NCBP2-AS2","3","","","",0,0,1.383,0.47,0.00112842225225784,0.0366844053367404,123.8,102.3,73.9,"",5.88,10.47,201,"","",163.5,170.6,168.7,149.4,140.1,123.5,110.2,116.8,10.2,"","",130.5,129.1,134,108.2,100.9,123.5,89.8,93.2,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q12882","Dihydropyrimidine dehydrogenase [NADP(+)] OS=Homo sapiens OX=9606 GN=DPYD PE=1 SV=2",0,35.509,13,13,15,13,1025,111.3,7.05,38.58,13,"metabolic process","cytoplasm;cytosol","catalytic activity;metal ion binding;nucleotide binding;protein binding","Pf01180, Pf01207, Pf07992, Pf12838, Pf13183, Pf13187, Pf13237, Pf13450, Pf14691, Pf14697","1806","ENSG00000188641.12","DPYD","1","Metabolic pathways; beta-Alanine metabolism; Pyrimidine metabolism; Pantothenate and CoA biosynthesis; Drug metabolism - other enzymes","Pyrimidine catabolism","Fluoropyrimidine Activity; TYROBP Causal Network",11,0,1.276,0.35,0.00120070410744533,0.0380518442641398,101.8,111.1,87.1,"",4.37,8.61,875.1,"","",976.6,933.9,908.8,1001.9,739.3,758,686.5,843.4,44.4,"","",779.3,706.9,721.7,725.6,532.5,758,559.5,673,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P05107","Integrin beta-2 OS=Homo sapiens OX=9606 GN=ITGB2 PE=1 SV=2",0,6.973,3,2,2,2,769,84.7,6.95,5.23,2,"cell communication;cell death;cell differentiation;cell organization and biogenesis;cellular component movement;defense response;metabolic process;regulation of biological process;response to stimulus;transport","cell surface;membrane","metal ion binding;protein binding;receptor activity;signal transducer activity","Pf00362, Pf07965, Pf08725","3689","","ITGB2","21","Rheumatoid arthritis; HTLV-I infection; Leukocyte transendothelial migration; Cell adhesion molecules (CAMs); Phagosome; Amoebiasis; Viral myocarditis; Natural killer cell mediated cytotoxicity; Malaria; Hippo signaling pathway; Staphylococcus aureus infection; Tuberculosis; Complement and coagulation cascades; Leishmaniasis; Legionellosis; Pertussis; Regulation of actin cytoskeleton; Rap1 signaling pathway","Integrin cell surface interactions; Neutrophil degranulation; Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell; Toll Like Receptor 4 (TLR4) Cascade; Cell surface interactions at the vascular wall; Interleukin-4 and 13 signaling","Integrin-mediated Cell Adhesion; Focal Adhesion; Focal Adhesion-PI3K-Akt-mTOR-signaling pathway; Microglia Pathogen Phagocytosis Pathway; TYROBP Causal Network",37,0,0.702,-0.51,1.22634379084796E-3,0.0387344172600941,93.3,85.3,121.4,"",6.51,8.8,63.1,"","",55.3,62.5,60.1,54.7,84.8,87.1,71.2,79.3,3.2,"","",44.1,47.3,47.7,39.6,61.1,87.1,58,63.3,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P05783","Keratin, type I cytoskeletal 18 OS=Homo sapiens OX=9606 GN=KRT18 PE=1 SV=2",0,436.754,86,45,399,43,430,48,5.45,1204.62,45,"cell death;cell organization and biogenesis;regulation of biological process;response to stimulus;transport","cytoplasm;cytosol;nucleus","protein binding;RNA binding;structural molecule activity","Pf00038","3875","ENSG00000111057.10","KRT18","12","Pathogenic Escherichia coli infection","Formation of the cornified envelope","Pathogenic Escherichia coli infection",5,2,0.82,-0.29,1.23405898860818E-3,0.0388460304576425,91.1,94.2,114.8,64.58,7.83,6.73,33895,8585.8,45791.1,32701.7,37147.3,33060.7,38069.6,40331.6,45743,40509.4,45054.5,1719.7,2.4,5.8,26096.1,28116.8,26253.4,27571.6,29047.9,45743,33015.6,35952.4,"High","High","High","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q8NBJ4","Golgi membrane protein 1 OS=Homo sapiens OX=9606 GN=GOLM1 PE=1 SV=1",0,92.514,48,21,23,21,401,45.3,4.97,66.98,21,"cell organization and biogenesis;metabolic process;regulation of biological process","Golgi;membrane;organelle lumen","protein binding","","51280","ENSG00000135052.16","GOLM1","9","","Post-translational protein phosphorylation; Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)","",4,0,1.283,0.36,1.24384793037247E-3,0.0388460304576425,192.9,60.2,46.9,113.13,19.32,8.39,2544.5,"",22895.5,2528.9,2265.7,2499.6,1604.9,1817.9,1893.5,1945.9,1600.2,129.1,"",2.9,2018.1,1714.9,1984.9,1162.3,1309.3,1893.5,1585.9,1276.9,"High","Not Found","High","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","O14545","TRAF-type zinc finger domain-containing protein 1 OS=Homo sapiens OX=9606 GN=TRAFD1 PE=1 SV=1",0,67.223,30,13,17,13,582,64.8,5.29,55.73,13,"regulation of biological process;response to stimulus","","metal ion binding;protein binding","","10906","ENSG00000135148.11","TRAFD1","12","","","Regulation of toll-like receptor signaling pathway",1,0,0.775,-0.37,0.00123285004048568,0.0388460304576425,230.1,30.5,39.4,137.39,26.17,9.68,650.4,"",45001.6,664.7,714.5,720.3,1117.9,888.9,820.7,1027,963.1,33,"",5.7,530.4,540.8,572,809.6,640.2,820.7,837,768.5,"High","Not Found","High","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q16134","Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial OS=Homo sapiens OX=9606 GN=ETFDH PE=1 SV=2",0,26.64,12,7,7,7,617,68.5,7.55,21.97,7,"metabolic process;response to stimulus;transport","membrane;mitochondrion;organelle lumen","catalytic activity;metal ion binding;nucleotide binding","Pf00890, Pf01266, Pf01494, Pf01946, Pf03486, Pf05187, Pf05834, Pf07992, Pf12831, Pf12838, Pf13450, Pf13454, Pf13738","2110","ENSG00000171503.11","ETFDH","4","","Respiratory electron transport","",4,0,1.277,0.35,1.26532723005512E-3,0.0391795093791495,206.4,52.5,41.1,126.25,6.08,3.23,1208.2,"",21316.5,1312.8,1286.8,1292.9,1146,1017,1069.8,1003.2,997.5,61.3,"",2.7,1047.6,974,1026.7,830,732.5,1069.8,817.6,796,"High","Not Found","High","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q96BD0","Solute carrier organic anion transporter family member 4A1 OS=Homo sapiens OX=9606 GN=SLCO4A1 PE=1 SV=2",0,16.921,6,3,3,3,722,77.1,7.83,11.7,3,"transport","membrane","protein binding;transporter activity","Pf03137, Pf07648, Pf07690","28231","ENSG00000101187.15","SLCO4A1","20","","Transport of organic anions","",4,0,1.273,0.35,0.00129500419954653,0.039902184863026,127.8,96.4,75.8,"",8.44,9.01,924.4,"","",658.3,738.8,624.6,740.4,506.2,586.6,511.6,601.9,46.9,"","",525.3,559.2,496,536.2,364.6,586.6,417,480.3,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q9Y5N6","Origin recognition complex subunit 6 OS=Homo sapiens OX=9606 GN=ORC6 PE=1 SV=1",0,14.743,17,5,6,5,252,28.1,8.66,17.22,5,"metabolic process;regulation of biological process","membrane;nucleus","DNA binding;protein binding","Pf05460","23594","ENSG00000091651.8","ORC6","16","Cell cycle","M/G1 Transition; CDT1 association with the CDC6:ORC:origin complex; Regulation of DNA replication; Activation of ATR in response to replication stress; Activation of the pre-replicative complex; CDC6 association with the ORC:origin complex; E2F-enabled inhibition of pre-replication complex formation; Assembly of the ORC complex at the origin of replication; Orc1 removal from chromatin; Removal of licensing factors from origins","Cell Cycle; G1 to S cell cycle control; DNA Replication",27,0,0.792,-0.34,1.36239127041415E-3,0.04177410116166,102.4,87.3,110.3,"",6.29,2.42,1200.3,"","",994.9,1053.8,930.6,1071.3,1329,1253.9,1285.7,1300.7,60.9,"","",793.9,797.6,739,775.9,957.2,1253.9,1047.9,1037.9,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"Medium","Master Protein","Q9UH17","DNA dC->dU-editing enzyme APOBEC-3B OS=Homo sapiens OX=9606 GN=APOBEC3B PE=1 SV=1",0.014,2.145,2,1,1,1,382,45.9,6.06,3.03,1,"defense response;regulation of biological process;response to stimulus","nucleus","catalytic activity;metal ion binding;RNA binding","Pf05240, Pf08210","9582","ENSG00000179750.15","APOBEC3B","22","","Formation of the Editosome","",4,0,0.713,-0.49,0.00138796665065066,0.0422156426690656,87.3,88.5,124.1,"",10.64,4.85,90.7,"","",87.7,94.3,89.5,110,125.7,128.4,129.3,140.1,4.6,"","",70,71.4,71.1,79.7,90.5,128.4,105.4,111.8,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q8WTS1","1-acylglycerol-3-phosphate O-acyltransferase ABHD5 OS=Homo sapiens OX=9606 GN=ABHD5 PE=1 SV=1",0,7.739,6,2,2,2,349,39.1,6.61,4.79,2,"cell differentiation;metabolic process;regulation of biological process","cytoplasm;cytosol","catalytic activity","Pf00561, Pf12695, Pf12697","51099","ENSG00000011198.7","ABHD5","3","Regulation of lipolysis in adipocytes","Triglyceride catabolism","",5,0,1.332,0.41,1.40768289858517E-3,0.0427063376543598,114.6,105.9,79.5,"",17.83,6.81,341,"","",317.9,312.2,364.7,232.8,239.1,233.8,256.9,217.8,17.3,"","",253.7,236.3,289.6,168.6,172.2,233.8,209.4,173.8,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P16402","Histone H1.3 OS=Homo sapiens OX=9606 GN=H1-3 PE=1 SV=2",0,97.282,27,12,100,1,221,22.3,11.02,322.61,12,"cell organization and biogenesis;metabolic process;regulation of biological process","chromosome;nucleus","DNA binding;RNA binding","Pf00538","3007","ENSG00000124575.6","HIST1H1D","6","","Formation of Senescence-Associated Heterochromatin Foci (SAHF); Activation of DNA fragmentation factor","",10,11,0.822,-0.28,0.00142755246073656,0.0429741694489355,127.7,77.8,94.6,48.71,6.12,10.89,15350,31481.2,"",13133.9,13002.1,14838,13650.8,17011,19481.4,15583,15572.7,778.8,8.8,"",10480.9,9841.3,11782.8,9886.5,12251.8,19481.4,12700.3,12426.6,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q96LJ7","Dehydrogenase/reductase SDR family member 1 OS=Homo sapiens OX=9606 GN=DHRS1 PE=1 SV=1",0,71.343,48,11,14,11,313,33.9,7.83,57.85,11,"metabolic process","endoplasmic reticulum;membrane;mitochondrion","catalytic activity;protein binding","Pf00106, Pf08659, Pf13561","115817","ENSG00000157379.13","DHRS1","14","","","",0,0,1.265,0.34,0.00142163270650952,0.0429741694489355,103.9,109.5,86.6,"",4.02,2.89,2524.8,"","",2680.3,2641.4,2680.4,2460.4,2219.4,2116.6,2090.2,2089.9,128.1,"","",2138.9,1999.3,2128.5,1781.9,1598.5,2116.6,1703.5,1667.7,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P09601","Heme oxygenase 1 OS=Homo sapiens OX=9606 GN=HMOX1 PE=1 SV=1",0,44.365,36,9,12,9,288,32.8,8.25,34.68,9,"cell communication;cell death;cell organization and biogenesis;cell proliferation;cellular homeostasis;metabolic process;regulation of biological process;response to stimulus","cytosol;endoplasmic reticulum;membrane;nucleus","catalytic activity;metal ion binding;protein binding;signal transducer activity","Pf01126","3162","ENSG00000100292.16","HMOX1","22","Mineral absorption; HIF-1 signaling pathway; MicroRNAs in cancer; Porphyrin and chlorophyll metabolism","Interleukin-4 and 13 signaling; Heme degradation; Iron uptake and transport","NRF2 pathway; Transcriptional activation by NRF2; Overview of nanoparticle effects; Photodynamic therapy-induced NFE2L2 (NRF2) survival signaling; Lung fibrosis; Oxidative Stress",19,0,1.273,0.35,0.00142883197871302,0.0429741694489355,97.9,113.2,88.9,"",16.44,16.38,1166.8,"","",1351.6,1368.2,1346.2,944,1160.2,1054,1065.5,775.1,59.2,"","",1078.6,1035.6,1069,683.7,835.6,1054,868.4,618.5,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P25788","Proteasome subunit alpha type-3 OS=Homo sapiens OX=9606 GN=PSMA3 PE=1 SV=2",0,63.487,40,12,41,12,255,28.4,5.33,112.8,12,"metabolic process;regulation of biological process;response to stimulus;transport","cytoplasm;cytosol;nucleus;proteasome","catalytic activity;nucleotide binding;protein binding","Pf00227, Pf10584","5684","ENSG00000100567.12","PSMA3","14","Proteasome","Regulation of RAS by GAPs; CDT1 association with the CDC6:ORC:origin complex; Downstream TCR signaling; UCH proteinases; NIK-->noncanonical NF-kB signaling; Hh mutants that don't undergo autocatalytic processing are degraded by ERAD; SCF-beta-TrCP mediated degradation of Emi1; Cross-presentation of soluble exogenous antigens (endosomes); Separation of Sister Chromatids; Vpu mediated degradation of CD4; Hedgehog ligand biogenesis; Regulation of RUNX2 expression and activity; Ub-specific processing proteases; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; ER-Phagosome pathway; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; ABC-family proteins mediated transport; Regulation of activated PAK-2p34 by proteasome mediated degradation; CDK-mediated phosphorylation and removal of Cdc6; FCERI mediated NF-kB activation; Neddylation; Autodegradation of the E3 ubiquitin ligase COP1; G2/M Checkpoints; Regulation of RUNX3 expression and activity; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Regulation of expression of SLITs and ROBOs; Removal of licensing factors from origins; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; Regulation of PTEN stability and activity; Regulation of DNA replication; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; Vif-mediated degradation of APOBEC3G; Antigen processing: Ubiquitination & Proteasome degradation; GLI3 is processed to GLI3R by the proteasome; SCF(Skp2)-mediated degradation of p27/p21; APC/C:Cdc20 mediated degradation of Securin; Interleukin-1 family signaling; AUF1 (hnRNP D0) binds and destabilizes mRNA; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; The role of GTSE1 in G2/M progression after G2 checkpoint; Regulation of ornithine decarboxylase (ODC); Interleukin-20 family signaling; Hedgehog 'on' state; Ubiquitin-dependent degradation of Cyclin D1; Degradation of DVL; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Degradation of AXIN; Autodegradation of Cdh1 by Cdh1:APC/C; Asymmetric localization of PCP proteins; Orc1 removal from chromatin; M/G1 Transition; Activation of NF-kappaB in B cells; Degradation of beta-catenin by the destruction complex; MAPK6/MAPK4 signaling; Dectin-1 mediated noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosis","Proteasome Degradation",150,0,0.823,-0.28,1.44362864682424E-3,0.0432813617162161,130.1,76.7,93.2,61.55,2.21,3.3,6052.9,15382.9,"",5722.9,5768.8,5647.3,5483.4,7189.5,6760.2,7065.7,6724.4,307.1,4.3,"",4566.9,4366.4,4484.5,3971.3,5178.1,6760.2,5758.6,5365.9,"High","High","High","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q02241","Kinesin-like protein KIF23 OS=Homo sapiens OX=9606 GN=KIF23 PE=1 SV=3",0,202.981,45,40,65,11,960,110,8.51,178.5,40,"cell division;cell organization and biogenesis;cellular component movement;regulation of biological process;transport","cytoplasm;cytoskeleton;cytosol;nucleus","catalytic activity;motor activity;nucleotide binding;protein binding","Pf00225, Pf02463, Pf03938, Pf05852, Pf11559, Pf12329, Pf15294","9493","ENSG00000137807.13","KIF23","15","MicroRNAs in cancer","COPI-dependent Golgi-to-ER retrograde traffic; Kinesins; MHC class II antigen presentation; Mitotic Telophase/Cytokinesis","",16,22,0.819,-0.29,0.00145135016993581,0.0434439017587124,114.5,83.5,102,46.85,4.27,3.18,5031.9,10016.8,"",5075.2,5283.3,4820.7,5277.4,6543.8,6419.3,6091.8,6224.1,255.3,2.8,"",4050,3998.9,3828.1,3822.1,4713,6419.3,4964.9,4966.7,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P23368","NAD-dependent malic enzyme, mitochondrial OS=Homo sapiens OX=9606 GN=ME2 PE=1 SV=1",0,64.378,35,17,20,16,584,65.4,7.61,58.98,17,"metabolic process;regulation of biological process","mitochondrion;organelle lumen","catalytic activity;metal ion binding;nucleotide binding","Pf00390, Pf03949","4200","ENSG00000082212.12","ME2","18","Carbon metabolism; Pyruvate metabolism","","",2,1,1.237,0.31,1.45558822405145E-3,0.043501820215006,106.3,107.1,86.6,"",8.7,3.55,3388.1,"","",3434.8,3393.4,3494.5,2872.9,2762.5,2815.1,2758.9,2591.7,171.9,"","",2741,2568.5,2775,2080.7,1989.6,2815.1,2248.5,2068.1,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q8NBP7","Proprotein convertase subtilisin/kexin type 9 OS=Homo sapiens OX=9606 GN=PCSK9 PE=1 SV=3",0,24.266,8,5,6,5,692,74.2,6.61,16.01,5,"cell communication;cell death;cell differentiation;metabolic process;regulation of biological process;response to stimulus;transport","cell surface;cytoplasm;endoplasmic reticulum;endosome;extracellular;Golgi;membrane;organelle lumen;vacuole","catalytic activity;protein binding;RNA binding","Pf00082, Pf05922","255738","ENSG00000169174.10","PCSK9","1","","Post-translational protein phosphorylation; Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs); LDL clearance; VLDLR internalisation and degradation","Proprotein convertase subtilisin/kexin type 9 (PCSK9) mediated LDL receptor degradation; Evolocumab Mechanism",11,0,1.375,0.46,0.0014768257563389,0.0439972947724433,101.4,115,83.6,"",15.78,13.2,80.8,"","",98.4,85.3,104,72.2,54.7,66.4,75.9,66.9,4.1,"","",78.5,64.6,82.6,52.3,39.4,66.4,61.9,53.4,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q8N8J7","Uncharacterized protein FAM241A OS=Homo sapiens OX=9606 GN=FAM241A PE=2 SV=2",0,6.365,13,1,1,1,132,14.6,4.7,3.52,1,"","membrane","","Pf15378","132720","ENSG00000174749.5","C4orf32; FAM241A","4","","","",0,0,1.399,0.48,1.47616290015495E-3,0.0439972947724433,98.1,117.8,84.2,"",12.21,8.91,55.2,"","",62.3,70.6,70.5,54.1,45.1,53.7,44.5,49.8,2.8,"","",49.7,53.4,56,39.2,32.5,53.7,36.3,39.7,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P05556","Integrin beta-1 OS=Homo sapiens OX=9606 GN=ITGB1 PE=1 SV=2",0,227.253,36,35,74,35,798,88.4,5.39,223.04,35,"cell differentiation;cell growth;cell organization and biogenesis;cellular component movement;defense response;metabolic process;regulation of biological process;response to stimulus;transport","cell surface;cytoplasm;endosome;membrane","enzyme regulator activity;metal ion binding;protein binding;receptor activity;signal transducer activity","Pf00362, Pf07965, Pf08725","3688","ENSG00000150093.18","ITGB1","10","Arrhythmogenic right ventricular cardiomyopathy (ARVC); ECM-receptor interaction; Proteoglycans in cancer; Pertussis; Dilated cardiomyopathy; PI3K-Akt signaling pathway; Bacterial invasion of epithelial cells; Phagosome; Cell adhesion molecules (CAMs); Shigellosis; Regulation of actin cytoskeleton; Leishmaniasis; Hypertrophic cardiomyopathy (HCM); Focal adhesion; Pathogenic Escherichia coli infection; Axon guidance; Toxoplasmosis; Small cell lung cancer; Pathways in cancer; Leukocyte transendothelial migration; Rap1 signaling pathway; Platelet activation","Integrin cell surface interactions; Signal transduction by L1; Basigin interactions; MET activates PTK2 signaling; Molecules associated with elastic fibres; Platelet Adhesion to exposed collagen; Syndecan interactions; CHL1 interactions; ECM proteoglycans; Laminin interactions; Localization of the PINCH-ILK-PARVIN complex to focal adhesions; Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell; MET interacts with TNS proteins; Other semaphorin interactions; RHO GTPases Activate Formins; Interleukin-4 and 13 signaling; Fibronectin matrix formation","Integrin-mediated Cell Adhesion; Prolactin Signaling Pathway; Neural Crest Differentiation; Arrhythmogenic Right Ventricular Cardiomyopathy; Pathogenic Escherichia coli infection; Primary Focal Segmental Glomerulosclerosis FSGS; Focal Adhesion; Signaling of Hepatocyte Growth Factor Receptor; Rac1/Pak1/p38/MMP-2 pathway; TGF-beta Signaling Pathway; Factors and pathways affecting insulin-like growth factor (IGF1)-Akt signaling; VEGFA-VEGFR2 Signaling Pathway; Focal Adhesion-PI3K-Akt-mTOR-signaling pathway",74,0,1.214,0.28,1.54975270003654E-3,0.0459839074112477,107.5,105.5,87,"",4.74,5.49,8688.1,"","",8367.9,8496.5,8562.2,9282,6816.5,7186.9,6872.7,7671.4,440.8,"","",6677.6,6431,6799.2,6722.4,4909.4,7186.9,5601.3,6121.6,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q9UBR2","Cathepsin Z OS=Homo sapiens OX=9606 GN=CTSZ PE=1 SV=1",0,48.594,36,11,14,11,303,33.8,7.11,32.08,11,"cell organization and biogenesis;metabolic process;regulation of biological process;transport","cell surface;endoplasmic reticulum;extracellular;membrane;organelle lumen;vacuole","catalytic activity;protein binding","Pf00112","1522","ENSG00000101160.13","CTSZ","20","Apoptosis; Lysosome","Metabolism of Angiotensinogen to Angiotensins; Neutrophil degranulation; Cargo concentration in the ER; COPII (Coat Protein 2) Mediated Vesicle Transport; Lysosome Vesicle Biogenesis","",19,0,1.282,0.36,0.00158118217022074,0.0466646387986396,216.9,46.7,36.4,130.53,22.7,30.56,885,"",22106,960.3,942.4,835.3,1365.2,1174.5,843.4,628.5,653.3,44.9,"",2.8,766.3,713.3,663.3,988.7,845.9,843.4,512.2,521.3,"High","Not Found","High","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q9H4F8","SPARC-related modular calcium-binding protein 1 OS=Homo sapiens OX=9606 GN=SMOC1 PE=1 SV=1",0,39.172,27,11,13,11,434,48.1,8.22,34.39,11,"cell differentiation;development;regulation of biological process;response to stimulus","extracellular","metal ion binding;protein binding","Pf00086, Pf07648, Pf10591","64093","ENSG00000198732.10","SMOC1","14","","","",0,0,1.26,0.33,0.00157964091030549,0.0466646387986396,106.1,108.1,85.8,"",5.42,11.69,1708.8,"","",1719.5,1642.9,1761.2,1870,1308.2,1424,1339.9,1678.9,86.7,"","",1372.2,1243.5,1398.6,1354.3,942.2,1424,1092,1339.7,"High","Not Found","High","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q9Y6M7-13","Isoform 13 of Sodium bicarbonate cotransporter 3 OS=Homo sapiens OX=9606 GN=SLC4A7",0,47.622,11,12,17,12,1135,127.7,6.8,39.92,12,"cellular homeostasis;transport","membrane","transporter activity","Pf00359, Pf00955, Pf07565","9497","","SLC4A7","3","","","",0,0,1.278,0.35,1.6279037311473E-3,0.0475947173658201,105.9,108.9,85.2,"",11.74,6.71,1291,"","",1305.4,1349.8,1378,1051.9,1053.7,1156,1023.3,992.6,65.5,"","",1041.7,1021.7,1094.3,761.8,758.9,1156,834,792.1,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","O75496","Geminin OS=Homo sapiens OX=9606 GN=GMNN PE=1 SV=1",0,26.429,19,4,5,4,209,23.6,4.96,13.25,4,"cell organization and biogenesis;metabolic process;regulation of biological process;transport","cytoplasm;cytosol;endoplasmic reticulum;nucleus","catalytic activity;protein binding","Pf00171, Pf05529, Pf07412, Pf10359","51053","ENSG00000112312.9","GMNN","6","","M/G1 Transition; CDT1 association with the CDC6:ORC:origin complex; Association of licensing factors with the pre-replicative complex; Cell Cycle, Mitotic; Regulation of DNA replication; Removal of licensing factors from origins","DNA Replication",11,0,0.788,-0.34,1.63033577592575E-3,0.0475947173658201,95.5,90.1,114.4,"",5.11,4.7,538.1,"","",510.4,504.6,458.4,511.2,637.9,604.6,677.4,650.3,27.3,"","",407.3,381.9,364,370.2,459.4,604.6,552.1,518.9,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q9UK22","F-box only protein 2 OS=Homo sapiens OX=9606 GN=FBXO2 PE=1 SV=2",0,25.603,26,5,5,5,296,33.3,4.37,16.91,5,"metabolic process;regulation of biological process","cytoplasm;cytosol;endoplasmic reticulum;membrane","catalytic activity;protein binding","Pf04300","26232","ENSG00000116661.9","FBXO2","1","Ubiquitin mediated proteolysis; Protein processing in endoplasmic reticulum","Antigen processing: Ubiquitination & Proteasome degradation; Neddylation","",9,0,0.779,-0.36,1.64072688392514E-3,0.0478241502832994,82.9,95.1,122,"",13.26,9.02,571.6,"","",604.3,710.8,602.1,786.9,776.3,899.6,786.2,924.6,29,"","",482.2,538,478.1,569.9,559.1,899.6,640.8,737.8,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P01033","Metalloproteinase inhibitor 1 OS=Homo sapiens OX=9606 GN=TIMP1 PE=1 SV=1",0,16.839,25,4,4,4,207,23.2,8.1,11.79,4,"cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus;transport","extracellular;organelle lumen","enzyme regulator activity;metal ion binding;protein binding","Pf00965","7076","ENSG00000102265.11","TIMP1","X","HIF-1 signaling pathway","Platelet degranulation ; Post-translational protein phosphorylation; Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs); Activation of Matrix Metalloproteinases; Interleukin-10 signaling; Interleukin-4 and 13 signaling","Matrix Metalloproteinases; IL1 and megakaryocytes in obesity; Lung fibrosis; IL-6 signaling pathway",21,0,1.285,0.36,0.00174910854001054,0.0505797613476121,111.5,106,82.5,"",10.04,4.29,794.3,"","",788.5,723.6,820.9,651.6,556.5,615.9,579.7,596.4,40.3,"","",629.2,547.7,651.9,471.9,400.8,615.9,472.5,475.9,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P04035","3-hydroxy-3-methylglutaryl-coenzyme A reductase OS=Homo sapiens OX=9606 GN=HMGCR PE=1 SV=1",0,42.87,13,8,9,8,888,97.4,6.74,33.14,8,"cell differentiation;cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus","endoplasmic reticulum;membrane","catalytic activity;nucleotide binding;protein binding","Pf00368, Pf02460, Pf12349","3156","ENSG00000113161.15","HMGCR","5","Metabolic pathways; Bile secretion; AMPK signaling pathway; Terpenoid backbone biosynthesis","Cholesterol biosynthesis; PPARA activates gene expression; Activation of gene expression by SREBF (SREBP)","AMP-activated Protein Kinase (AMPK) Signaling; Target Of Rapamycin (TOR) Signaling; Cholesterol Biosynthesis; Sterol Regulatory Element-Binding Proteins (SREBP) signalling; Integrated Breast Cancer Pathway; SREBF and miR33 in cholesterol and lipid homeostasis; Statin Pathway",19,0,1.346,0.43,0.00176215825245207,0.0507025616127621,110.3,108.8,80.8,"",9.16,5.95,378.4,"","",379.4,367,416.3,333.3,289.6,275.3,279.1,251.1,19.2,"","",302.8,277.8,330.6,241.4,208.6,275.3,227.5,200.4,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P20138","Myeloid cell surface antigen CD33 OS=Homo sapiens OX=9606 GN=CD33 PE=1 SV=2",0,19.56,13,5,5,5,364,39.8,8.38,17.91,5,"cell communication;regulation of biological process;response to stimulus;transport","membrane;nucleus","protein binding;receptor activity","Pf00047, Pf08205","945","ENSG00000105383.14","CD33","19","Hematopoietic cell lineage","Neutrophil degranulation; Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell","",6,0,1.323,0.4,0.00181262809707405,0.0517139819822173,110.3,108,81.7,"",1.94,2.95,445.4,"","",440,447.6,432.9,428.2,331.4,321.7,328.6,345,22.6,"","",351.1,338.8,343.8,310.1,238.7,321.7,267.8,275.3,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P50238","Cysteine-rich protein 1 OS=Homo sapiens OX=9606 GN=CRIP1 PE=1 SV=3",1E-3,4.924,31,3,8,3,77,8.5,8.75,11.16,3,"cell proliferation;regulation of biological process;response to stimulus","cytoplasm","DNA binding;metal ion binding","Pf00412","1396","ENSG00000257341.5; ENSG00000213145.9","CRIP1","14","","","",0,0,0.805,-0.31,0.00188026216820592,0.0533249126622723,93.7,92,114.3,"",6.64,5.87,1561,"","",1635.3,1607.3,1461.4,1432.8,1811.8,1842.9,1969.2,2054.5,79.2,"","",1305,1216.6,1160.5,1037.7,1304.9,1842.9,1604.9,1639.4,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q96GD4","Aurora kinase B OS=Homo sapiens OX=9606 GN=AURKB PE=1 SV=3",0,30.772,24,8,11,8,344,39.3,9.29,29.94,8,"cell division;cell organization and biogenesis;cell proliferation;metabolic process;regulation of biological process;response to stimulus","chromosome;cytoplasm;cytoskeleton;cytosol;nucleus","catalytic activity;metal ion binding;nucleotide binding;protein binding","Pf00069, Pf07714","9212","ENSG00000178999.12","AURKB","17","","APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; SUMOylation of DNA replication proteins; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal; Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; Regulation of TP53 Activity through Phosphorylation","Regulation of Microtubule Cytoskeleton; ATM Signaling Network in Development and Disease",32,0,0.776,-0.37,1.90134758907723E-3,0.0536810960575347,120.8,78.3,100.9,"",12.35,8.04,875.1,"","",517.2,546.8,589.1,682.6,701.7,686.4,761.5,816.7,44.4,"","",412.7,413.9,467.8,494.4,505.4,686.4,620.6,651.7,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"Low","Master Protein","P08F94","Fibrocystin OS=Homo sapiens OX=9606 GN=PKHD1 PE=1 SV=1",0.075,1.181,0,1,1,1,4074,446.4,6.57,2.15,1,"cell organization and biogenesis;cellular homeostasis;regulation of biological process","chromosome;cytoplasm;cytoskeleton;membrane","protein binding;receptor activity","Pf01833, Pf10162, Pf13229","5314","ENSG00000170927.14","PKHD1","6","","","",0,0,1.362,0.45,0.0019240034902146,0.0542396685420498,110.7,109.1,80.2,"",3.2,4.28,134,"","",130.2,135.9,134.1,126.5,99.1,95,93.4,102.6,6.8,"","",103.9,102.9,106.5,91.6,71.4,95,76.1,81.9,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P04792","Heat shock protein beta-1 OS=Homo sapiens OX=9606 GN=HSPB1 PE=1 SV=2",0,104.494,71,18,55,18,205,22.8,6.4,153.81,18,"cellular component movement;metabolic process;regulation of biological process;response to stimulus","cytoplasm;cytoskeleton;cytosol;membrane;nucleus;proteasome","enzyme regulator activity;protein binding;RNA binding","Pf00011","3315","ENSG00000106211.8","HSPB1","7","MAPK signaling pathway; Amoebiasis; Epstein-Barr virus infection; VEGF signaling pathway","AUF1 (hnRNP D0) binds and destabilizes mRNA; VEGFA-VEGFR2 Pathway; MAPK6/MAPK4 signaling","Apoptosis-related network due to altered Notch3 in ovarian cancer; Fas Ligand (FasL) pathway and Stress induction of Heat Shock Proteins (HSP) regulation; MAPK Signaling Pathway; ATM Signaling Network in Development and Disease; VEGFA-VEGFR2 Signaling Pathway; p38 MAPK Signaling Pathway",19,0,1.209,0.27,1.93257056845297E-3,0.0543999894142172,169.5,71.4,59.1,99.77,4.63,5.14,7968.7,46148.6,"",8262,8179.4,7978,7441.6,6545,6689.4,7324.3,6676,404.3,12.9,"",6593.1,6191,6335.3,5389.5,4713.9,6689.4,5969.4,5327.3,"High","High","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P67936-2","Isoform 2 of Tropomyosin alpha-4 chain OS=Homo sapiens OX=9606 GN=TPM4",0,122.612,55,26,91,5,284,32.7,4.73,258.05,26,"cell differentiation;cell organization and biogenesis;cellular component movement","cytoskeleton;cytosol;membrane","metal ion binding;protein binding;structural molecule activity","Pf00261, Pf12718","7171","ENSG00000167460.14","TPM4","19","","","Striated Muscle Contraction",1,0,1.271,0.35,1.94362325828856E-3,0.0546296965811821,96.2,114,89.7,"",4.87,1.17,542,"","",637.2,647.4,592.5,665.2,498.5,508.7,511.2,501.8,27.5,"","",508.5,490,470.5,481.8,359,508.7,416.6,400.4,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P38936","Cyclin-dependent kinase inhibitor 1 OS=Homo sapiens OX=9606 GN=CDKN1A PE=1 SV=3",0,6.468,9,1,1,1,164,18.1,8.37,4.09,1,"cell communication;metabolic process;regulation of biological process;response to stimulus","cytoplasm;cytosol;nucleus","catalytic activity;enzyme regulator activity;metal ion binding;protein binding","Pf02234","1026","ENSG00000124762.13","CDKN1A","6","Pathways in cancer; Hepatitis C; Oxytocin signaling pathway; Transcriptional misregulation in cancer; MicroRNAs in cancer; HTLV-I infection; Hepatitis B; Prostate cancer; Endocrine resistance; Breast cancer; Bladder cancer; Chronic myeloid leukemia; Proteoglycans in cancer; HIF-1 signaling pathway; Melanoma; Platinum drug resistance; Cell cycle; p53 signaling pathway; Jak-STAT signaling pathway; Glioma; ErbB signaling pathway; Epstein-Barr virus infection; FoxO signaling pathway; Viral carcinogenesis; PI3K-Akt signaling pathway","TFAP2 (AP-2) family regulates transcription of cell cycle factors; Regulation of DNA replication; TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest; SCF(Skp2)-mediated degradation of p27/p21; Transcriptional  activation of  cell cycle inhibitor p21 ; The role of GTSE1 in G2/M progression after G2 checkpoint; Transcriptional regulation by RUNX2; AKT phosphorylates targets in the cytosol; Cyclin D associated events in G1; Constitutive Signaling by AKT1 E17K in Cancer; Orc1 removal from chromatin; Interleukin-4 and 13 signaling; DNA Damage/Telomere Stress Induced Senescence; Senescence-Associated Secretory Phenotype (SASP); RUNX3 regulates CDKN1A transcription; Removal of licensing factors from origins","Androgen receptor signaling pathway; AMP-activated Protein Kinase (AMPK) Signaling; miRNA Regulation of DNA Damage Response; miRNAs involved in DNA damage response; TP53 Network; Cell Cycle; Integrated Cancer pathway; Signaling Pathways in Glioblastoma; Adipogenesis; Retinoblastoma (RB) in Cancer; ATM Signaling Pathway; Primary Focal Segmental Glomerulosclerosis FSGS; Aryl Hydrocarbon Receptor; Bladder Cancer; Apoptosis-related network due to altered Notch3 in ovarian cancer; miR-517 relationship with ARCN1 and USP1; Hepatitis C and Hepatocellular Carcinoma; TGF-beta Signaling Pathway; LncRNA-mediated mechanisms of therapeutic resistance; Association Between Physico-Chemical Features and Toxicity Associated Pathways; Focal Adhesion-PI3K-Akt-mTOR-signaling pathway; Oxidative Damage; G1 to S cell cycle control; Notch Signaling Pathway; Senescence and Autophagy in Cancer; ErbB Signaling Pathway; DNA Damage Response; DNA Damage Response (only ATM dependent)",106,0,1.486,0.57,2.01910814228246E-3,0.056499132728046,"",179.3,120.7,"",23.13,6.3,"","","",28.8,27.7,27.3,16.4,18.5,18.6,17.8,20.6,"","","",23,21,21.7,11.9,13.3,18.6,14.5,16.4,"Not Found","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q13275","Semaphorin-3F OS=Homo sapiens OX=9606 GN=SEMA3F PE=2 SV=2",0,14.975,6,4,5,4,785,88.3,8.27,15.19,4,"cell growth;cellular component movement;regulation of biological process;response to stimulus","extracellular;membrane","protein binding","Pf01403, Pf01437, Pf07679","6405","ENSG00000001617.11","SEMA3F","3","Axon guidance","","",1,0,1.357,0.44,0.00203527104364465,0.0568671589827812,81.6,125.8,92.7,"",15.48,6.73,84.8,"","",126.8,137.3,134.6,95.7,96.4,90.2,96.2,106,4.3,"","",101.2,103.9,106.9,69.3,69.4,90.2,78.4,84.6,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P30740","Leukocyte elastase inhibitor OS=Homo sapiens OX=9606 GN=SERPINB1 PE=1 SV=1",0,119.979,36,20,39,20,379,42.7,6.28,125.25,20,"regulation of biological process;transport","cytoplasm;extracellular;membrane;organelle lumen","enzyme regulator activity","Pf00079","1992","ENSG00000021355.12","SERPINB1","6","Amoebiasis","Neutrophil degranulation","",4,0,1.21,0.27,0.00206080550934629,0.0573389284339453,106.3,106.1,87.7,"",0.95,2.03,6636.3,"","",6688.7,6671.7,6575.5,6567.8,5367.3,5486.1,5464.7,5637.3,336.7,"","",5337.6,5049.8,5221.6,4756.7,3865.7,5486.1,4453.8,4498.4,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q9NSG2","Uncharacterized protein C1orf112 OS=Homo sapiens OX=9606 GN=C1orf112 PE=1 SV=1",0,20.947,5,5,5,5,853,96.5,6,12.57,5,"","","","Pf14868","55732","ENSG00000000460.16","C1orf112","1","","","",0,0,0.752,-0.41,2.06429856708401E-3,0.0573389284339453,85.6,92,122.4,"",24.69,8.21,270,"","",267.4,284.6,295.6,439.8,395.6,328.8,390.3,381.3,13.7,"","",213.4,215.4,234.7,318.5,284.9,328.8,318.1,304.3,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q9NVD7","Alpha-parvin OS=Homo sapiens OX=9606 GN=PARVA PE=1 SV=1",0,30.153,23,10,13,9,372,42.2,5.95,36.87,10,"cell organization and biogenesis;cellular component movement;regulation of biological process;response to stimulus","cytoplasm;cytoskeleton;cytosol;membrane","protein binding","Pf00307","55742","","PARVA","11","Focal adhesion","Localization of the PINCH-ILK-PARVIN complex to focal adhesions; Regulation of cytoskeletal remodeling and cell spreading by IPP complex components","Primary Focal Segmental Glomerulosclerosis FSGS",7,1,0.8,-0.32,0.00207780829210225,0.0576294317492323,168.7,58.4,73,108.66,2.64,4.02,1265.4,9659,"",1160.3,1207.8,1211.7,1236.5,1579.2,1507.3,1516.9,1431.4,64.2,2.7,"",925.9,914.2,962.2,895.5,1137.4,1507.3,1236.3,1142.2,"High","High","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q8NHP8","Putative phospholipase B-like 2 OS=Homo sapiens OX=9606 GN=PLBD2 PE=1 SV=2",0,29.581,13,7,9,7,589,65.4,6.8,25.84,7,"metabolic process","organelle lumen;vacuole","catalytic activity","Pf04916","196463","ENSG00000151176.7","PLBD2","12","","","",0,0,1.258,0.33,0.00211390689654567,0.0583734992133839,105.3,108.4,86.2,"",6.45,5.29,922.4,"","",950,949.3,986.7,846.7,770.3,810.2,740,717.3,46.8,"","",758.1,718.5,783.5,613.2,554.8,810.2,603.1,572.4,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P51825-2","Isoform 2 of AF4/FMR2 family member 1 OS=Homo sapiens OX=9606 GN=AFF1",0,27.204,7,8,8,8,1218,132.3,9.22,21.88,8,"regulation of biological process","","protein binding","Pf05110","4299","ENSG00000172493.20","AFF1","4","","","",0,0,0.756,-0.4,0.00211884137774931,0.0584243444422322,61.5,102.6,135.8,"",7.42,4.82,175.4,"","",298.6,279.2,286.6,329.4,372.9,371.9,402,407.3,8.9,"","",238.3,211.3,227.6,238.6,268.6,371.9,327.6,325,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q9ULV3","Cip1-interacting zinc finger protein OS=Homo sapiens OX=9606 GN=CIZ1 PE=1 SV=2",0,75.02,22,13,16,13,898,100,6.11,53.32,13,"","membrane;nucleus","metal ion binding;protein binding","Pf12171","25792","ENSG00000148337.20","CIZ1","9","","","",0,0,0.789,-0.34,0.00214688803491447,0.0589395657027101,83.1,95.7,121.3,"",1.75,3.23,798.2,"","",907,907.6,938.3,931.2,1209.8,1125.8,1147,1185,40.5,"","",723.8,687,745.1,674.4,871.3,1125.8,934.8,945.6,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"Medium","Master Protein","P81605-3","Isoform 3 of Dermcidin OS=Homo sapiens OX=9606 GN=DCD",0.016,2.032,14,1,1,1,77,8.3,9.42,2.24,1,"defense response;metabolic process;response to stimulus","extracellular","catalytic activity;protein binding;RNA binding","","117159","ENSG00000161634.11","DCD","12","","","",0,0,0.721,-0.47,0.00215391022786782,0.0589609512811121,90.6,87.7,121.7,"",47.94,151.66,76.9,"","",149.2,92.1,60.1,56.6,1269.9,169.5,62.8,53.1,3.9,"","",119.1,69.7,47.7,41,914.6,169.5,51.2,42.4,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q5QNW6","Histone H2B type 2-F OS=Homo sapiens OX=9606 GN=HIST2H2BF PE=1 SV=3",0,113.561,52,8,159,4,126,13.9,10.32,483.01,8,"cell organization and biogenesis","chromosome;cytosol;nucleus","DNA binding;protein binding","Pf00125, Pf00808","440689","ENSG00000203814.6","HIST2H2BF","1","Viral carcinogenesis; Systemic lupus erythematosus; Alcoholism","HDACs deacetylate histones; HATs acetylate histones; Ub-specific processing proteases","",11,11,0.829,-0.27,2.19321563670638E-3,0.059094803061498,91.3,94.6,114.1,11.75,10.15,3.92,20929.9,19675.8,16579.5,20284.1,18795.3,20487.4,23809.5,24119.7,24540.9,24652.7,26334.4,1061.9,5.5,2.1,16186.8,14226.2,16269,17243.8,17371.7,24540.9,20092.2,21014.2,"High","High","High","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q562F6","Shugoshin 2 OS=Homo sapiens OX=9606 GN=SGO2 PE=1 SV=2",0,14.257,4,4,4,4,1265,144.7,7.91,10.26,4,"cell division;cell organization and biogenesis","chromosome;cytosol;nucleus","protein binding","","151246","ENSG00000163535.17","SGOL2; SGO2","2","","Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal; Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins","",16,0,0.648,-0.63,0.0022233027455183,0.0597085404155972,"",117.9,182.1,"",23.01,4.93,"","","",12.8,12.7,15.2,20.2,21.8,21.3,22,19.7,"","","",10.2,9.6,12.1,14.6,15.7,21.3,17.9,15.7,"Not Found","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"Medium","Master Protein","P49184","Deoxyribonuclease-1-like 1 OS=Homo sapiens OX=9606 GN=DNASE1L1 PE=1 SV=1",0.016,2.008,3,1,1,1,302,33.9,5.74,2.57,1,"metabolic process;transport","endoplasmic reticulum;extracellular;nucleus;organelle lumen","catalytic activity;DNA binding","Pf03372","1774","ENSG00000013563.13","DNASE1L1","X","","Neutrophil degranulation","",3,0,1.35,0.43,0.00222969295334252,0.0597085404155972,114.9,106.3,78.8,"",25.8,12.53,193.2,"","",175.1,182.5,194.3,101.2,120.1,145.9,149.6,117.8,9.8,"","",139.7,138.1,154.3,73.3,86.5,145.9,121.9,94,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q9NR46","Endophilin-B2 OS=Homo sapiens OX=9606 GN=SH3GLB2 PE=1 SV=1",0,48.402,29,11,17,11,395,43.9,5.99,53.16,11,"","cytoplasm;cytosol","protein binding","Pf03114, Pf14604","56904","ENSG00000148341.17","SH3GLB2","9","Endocytosis","","",1,0,0.814,-0.3,0.00227974490834115,0.0607331760631138,94,92.4,113.6,"",4.88,1.37,3683.8,"","",3615,3628.5,3454.5,3885,4468.9,4430.2,4350.5,4487.4,186.9,"","",2884.8,2746.4,2743.2,2813.7,3218.6,4430.2,3545.7,3580.8,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q3KQV9","UDP-N-acetylhexosamine pyrophosphorylase-like protein 1 OS=Homo sapiens OX=9606 GN=UAP1L1 PE=1 SV=2",0,10.557,8,5,6,4,507,57,6.32,12.56,5,"metabolic process","cytosol","catalytic activity","Pf01704","91373","ENSG00000197355.10","UAP1L1","9","Amino sugar and nucleotide sugar metabolism; Metabolic pathways","","",2,0,0.739,-0.44,0.00228391763450286,0.0607586426485776,92.5,88.2,119.3,"",5.65,6.31,220.8,"","",212.3,188,211.9,208.8,280.7,288.7,297.9,256.5,11.2,"","",169.4,142.3,168.3,151.2,202.2,288.7,242.8,204.7,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P05121","Plasminogen activator inhibitor 1 OS=Homo sapiens OX=9606 GN=SERPINE1 PE=1 SV=1",0.009,2.544,2,1,1,1,402,45,7.2,2.72,1,"cell organization and biogenesis;defense response;regulation of biological process;response to stimulus;transport","extracellular;membrane;organelle lumen","enzyme regulator activity;protein binding","Pf00079","5054","ENSG00000106366.8","SERPINE1","7","Hippo signaling pathway; Complement and coagulation cascades; HIF-1 signaling pathway; AGE-RAGE signaling pathway in diabetic complications; Chagas disease (American trypanosomiasis); p53 signaling pathway","Dissolution of Fibrin Clot; Platelet degranulation ; ECM proteoglycans; SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription; BMAL1:CLOCK,NPAS2 activates circadian gene expression","Selenium Micronutrient Network; Vitamin B12 Metabolism; Folate Metabolism; Adipogenesis; Oncostatin M Signaling Pathway; Blood Clotting Cascade; Photodynamic therapy-induced HIF-1 survival signaling; Hypothesized Pathways in Pathogenesis of Cardiovascular Disease; Complement and Coagulation Cascades; TGF-beta Receptor Signaling; Senescence and Autophagy in Cancer",34,0,1.38,0.47,0.00230394400823952,0.0611192337466687,70.9,132.9,96.3,"",19.58,2.84,35.5,"","",60.8,72.8,79.1,50.1,47.9,49.8,48.5,46.5,1.8,"","",48.5,55.1,62.8,36.3,34.5,49.8,39.5,37.1,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q6NXR4","TELO2-interacting protein 2 OS=Homo sapiens OX=9606 GN=TTI2 PE=1 SV=1",0,48.557,25,9,11,9,508,56.9,7.09,31.88,9,"","cytosol","","Pf10521","80185","ENSG00000129696.12","TTI2","8","","","",0,0,0.81,-0.3,0.0023527341936318,0.062064865152678,46.9,113.3,139.8,"",11.3,21.44,652.4,"","",1592.2,1352.6,1786.9,1562.5,1763.9,1491.1,2447.4,2147.1,33.1,"","",1270.6,1023.8,1419,1131.6,1270.4,1491.1,1994.7,1713.3,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q01581","Hydroxymethylglutaryl-CoA synthase, cytoplasmic OS=Homo sapiens OX=9606 GN=HMGCS1 PE=1 SV=2",0,38.852,19,9,10,9,520,57.3,5.41,30.02,9,"metabolic process;regulation of biological process;response to stimulus","cytoplasm;cytosol","catalytic activity;protein binding","Pf01154, Pf08540","3157","ENSG00000112972.14","HMGCS1","5","Terpenoid backbone biosynthesis; Metabolic pathways; Butanoate metabolism; Valine, leucine and isoleucine degradation; Synthesis and degradation of ketone bodies","Cholesterol biosynthesis; PPARA activates gene expression; Activation of gene expression by SREBF (SREBP)","Cholesterol Biosynthesis; Sterol Regulatory Element-Binding Proteins (SREBP) signalling; SREBF and miR33 in cholesterol and lipid homeostasis; Endochondral Ossification",17,0,0.809,-0.31,2.35196171432817E-3,0.062064865152678,88,94.8,117.2,"",1.12,9.05,1275.2,"","",1373.8,1360.3,1373.3,1397.3,1870.9,1653.3,1742.4,1506.7,64.7,"","",1096.3,1029.6,1090.5,1012,1347.5,1653.3,1420.1,1202.3,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q9Y618","Nuclear receptor corepressor 2 OS=Homo sapiens OX=9606 GN=NCOR2 PE=1 SV=3",0,134.239,19,37,41,35,2514,273.5,7.59,108.93,37,"","","","","","","","","","","",0,0,0.816,-0.29,2.37908749092042E-3,0.0624113951784789,116.7,82.3,101,47.25,14.64,6.87,3928.2,7870.3,"",3855.9,3789.4,3989.9,5091.5,4687,4298.9,4934.7,5027.5,199.3,2.2,"",3077,2868.2,3168.4,3687.5,3375.7,4298.9,4021.8,4011.8,"High","High","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P60900","Proteasome subunit alpha type-6 OS=Homo sapiens OX=9606 GN=PSMA6 PE=1 SV=1",0,107.986,50,15,45,15,246,27.4,6.76,149.93,15,"metabolic process;regulation of biological process;response to stimulus;transport","cytoplasm;cytosol;nucleus;proteasome","catalytic activity;nucleotide binding;protein binding;RNA binding","Pf00227, Pf10584","5687","ENSG00000100902.10","PSMA6","14","Proteasome","Regulation of RAS by GAPs; CDT1 association with the CDC6:ORC:origin complex; Downstream TCR signaling; UCH proteinases; NIK-->noncanonical NF-kB signaling; Hh mutants that don't undergo autocatalytic processing are degraded by ERAD; SCF-beta-TrCP mediated degradation of Emi1; Cross-presentation of soluble exogenous antigens (endosomes); Separation of Sister Chromatids; Vpu mediated degradation of CD4; Hedgehog ligand biogenesis; Regulation of RUNX2 expression and activity; Ub-specific processing proteases; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; ER-Phagosome pathway; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; ABC-family proteins mediated transport; Regulation of activated PAK-2p34 by proteasome mediated degradation; CDK-mediated phosphorylation and removal of Cdc6; FCERI mediated NF-kB activation; Neddylation; Autodegradation of the E3 ubiquitin ligase COP1; G2/M Checkpoints; Regulation of RUNX3 expression and activity; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Regulation of expression of SLITs and ROBOs; Removal of licensing factors from origins; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; Regulation of PTEN stability and activity; Regulation of DNA replication; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; Vif-mediated degradation of APOBEC3G; Antigen processing: Ubiquitination & Proteasome degradation; GLI3 is processed to GLI3R by the proteasome; SCF(Skp2)-mediated degradation of p27/p21; APC/C:Cdc20 mediated degradation of Securin; Interleukin-1 family signaling; AUF1 (hnRNP D0) binds and destabilizes mRNA; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; The role of GTSE1 in G2/M progression after G2 checkpoint; Regulation of ornithine decarboxylase (ODC); Interleukin-20 family signaling; Hedgehog 'on' state; Ubiquitin-dependent degradation of Cyclin D1; Degradation of DVL; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Degradation of AXIN; Autodegradation of Cdh1 by Cdh1:APC/C; Asymmetric localization of PCP proteins; Orc1 removal from chromatin; M/G1 Transition; Activation of NF-kappaB in B cells; Degradation of beta-catenin by the destruction complex; MAPK6/MAPK4 signaling; Dectin-1 mediated noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosis","Proteasome Degradation",150,0,0.821,-0.28,0.002375491730223,0.0624113951784789,110.3,85.6,104.2,23.41,5.58,5.02,5122.6,7154.8,"",4678,4717.9,4754.2,4208,5668.5,5769.8,5855.3,5220.2,259.9,2,"",3733.1,3571,3775.3,3047.6,4082.6,5769.8,4772.1,4165.6,"High","High","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q5T280","Putative methyltransferase C9orf114 OS=Homo sapiens OX=9606 GN=SPOUT1 PE=1 SV=3",0,30.825,22,7,10,7,376,42,7.43,33.52,7,"cell division;metabolic process;regulation of biological process;response to stimulus","chromosome;cytoplasm;cytoskeleton","catalytic activity;RNA binding","Pf02598","51490","ENSG00000198917.12","C9orf114; SPOUT1","9","","","",0,0,0.806,-0.31,0.00241336919006208,0.0632229088237066,89.6,93.9,116.5,"",4.59,3.59,967.8,"","",1019.7,1008.5,1027.3,928.3,1332.1,1262.3,1254.8,1224.5,49.1,"","",813.7,763.3,815.8,672.3,959.4,1262.3,1022.7,977.1,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P63167","Dynein light chain 1, cytoplasmic OS=Homo sapiens OX=9606 GN=DYNLL1 PE=1 SV=1",0,36.325,46,4,20,3,89,10.4,7.4,61.63,4,"cell communication;cell death;cell organization and biogenesis;cellular component movement;metabolic process;regulation of biological process;response to stimulus;transport","chromosome;cytoplasm;cytoskeleton;cytosol;membrane;mitochondrion;nucleus","catalytic activity;motor activity;protein binding","Pf01221","8655","ENSG00000088986.10","DYNLL1","12","Vasopressin-regulated water reabsorption","COPI-independent Golgi-to-ER retrograde traffic; Regulation of PLK1 Activity at G2/M Transition; Recruitment of NuMA to mitotic centrosomes; Loss of Nlp from mitotic centrosomes; Neutrophil degranulation; Separation of Sister Chromatids; COPI-mediated anterograde transport; HSP90 chaperone cycle for steroid hormone receptors (SHR); AURKA Activation by TPX2; Anchoring of the basal body to the plasma membrane; Activation of BIM and translocation to mitochondria ; Recruitment of mitotic centrosome proteins and complexes; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal; Resolution of Sister Chromatid Cohesion; Intraflagellar transport; RHO GTPases Activate Formins; MHC class II antigen presentation; Macroautophagy","",55,1,0.8,-0.32,0.00249407773124655,0.0649767450865997,185.4,50.9,63.7,128.78,23.05,14.74,849.5,"",18158.5,1104.9,946.1,1053,1555,1322.6,992.3,1389.6,1374.6,43.1,"",2.3,881.7,716.1,836.2,1126.2,952.6,992.3,1132.5,1096.9,"High","High","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q92754","Transcription factor AP-2 gamma OS=Homo sapiens OX=9606 GN=TFAP2C PE=1 SV=1",0,17.41,9,6,7,2,450,49.1,7.83,15.68,6,"cell communication;metabolic process;regulation of biological process","cytosol;mitochondrion;nucleus","DNA binding;protein binding","Pf03299","7022","ENSG00000087510.6","TFAP2C","20","","TFAP2 (AP-2) family regulates transcription of cell cycle factors; Negative regulation of activity of TFAP2 (AP-2) family transcription factors; TFAP2 (AP-2) family regulates transcription of growth factors and their receptors; Activation of the TFAP2 (AP-2) family of transcription factors; TFAP2 (AP-2) family regulates transcription of other transcription factors; SUMOylation of transcription factors","Ectoderm Differentiation",15,0,0.746,-0.42,0.00252878624147135,0.065699744881583,81.1,93.5,125.4,"",9.39,6.33,189.2,"","",190.3,231.2,205.8,231.3,299.8,285.2,264.5,305.5,9.6,"","",151.9,175,163.4,167.5,215.9,285.2,215.6,243.8,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q8N4H5","Mitochondrial import receptor subunit TOM5 homolog OS=Homo sapiens OX=9606 GN=TOMM5 PE=1 SV=1",0,6.83,27,2,4,2,51,6,9.7,8.57,2,"cell communication;metabolic process;response to stimulus;transport","membrane;mitochondrion","transporter activity","Pf15178","401505","ENSG00000175768.12","TOMM5","9","","Mitochondrial protein import; Metabolism of proteins; Pink/Parkin Mediated Mitophagy","",4,0,1.255,0.33,0.00257307784412553,0.0664846707521791,101.5,110.5,88,"",14.79,2.4,1261.4,"","",1396.4,1412.6,1349.8,1008,1105.2,1135.9,1078.3,1082.6,64,"","",1114.3,1069.2,1071.9,730,796,1135.9,878.8,863.9,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q96AY3","Peptidyl-prolyl cis-trans isomerase FKBP10 OS=Homo sapiens OX=9606 GN=FKBP10 PE=1 SV=1",0,155.982,44,25,60,12,582,64.2,5.62,173.52,25,"cell organization and biogenesis;metabolic process","cytoplasm;endoplasmic reticulum;organelle lumen","catalytic activity;metal ion binding","Pf00254","60681","ENSG00000141756.18","FKBP10","17","","","",0,13,1.202,0.27,0.00258978669621879,0.0667338214436295,143.6,85.4,71,70.07,7.99,2.41,7990.4,"",23685,8212.2,7985.5,8143,9450.2,6817.4,6799.4,6483.3,6803.5,405.4,"",3,6553.4,6044.2,6466.3,6844.2,4910.1,6799.4,5284,5429,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P28347-2","Isoform 2 of Transcriptional enhancer factor TEF-1 OS=Homo sapiens OX=9606 GN=TEAD1",0,21.126,16,6,8,2,357,40,8.32,23.6,6,"cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus","","DNA binding;protein binding","Pf01285","7003","ENSG00000187079.16","TEAD1","11","","","Mesodermal Commitment Pathway; miR-509-3p alteration of YAP1/ECM axis",2,4,0.785,-0.35,0.00267329518783299,0.0686048906355836,93.2,90.9,115.8,"",1.7,3.69,821.9,"","",777.7,803.4,808.5,799.3,1083,1035.8,1006.5,999.2,41.7,"","",620.6,608.1,642,578.9,780,1035.8,820.3,797.3,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q9Y2I9","TBC1 domain family member 30 OS=Homo sapiens OX=9606 GN=TBC1D30 PE=1 SV=2",0.007,2.634,2,1,1,1,924,102.7,8.29,2.29,1,"regulation of biological process;transport","cytosol;membrane","enzyme regulator activity;protein binding","Pf00566","23329","","TBC1D30","12","","","",0,0,1.375,0.46,0.00274009011052079,0.0701284851050361,115.5,106.8,77.7,"",4.59,11.74,74.9,"","",71.3,65,71.4,67.2,42.5,56.7,49.4,51.3,3.8,"","",56.9,49.2,56.7,48.7,30.6,56.7,40.3,40.9,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q9H2H9","Sodium-coupled neutral amino acid transporter 1 OS=Homo sapiens OX=9606 GN=SLC38A1 PE=1 SV=1",0,7.007,4,2,2,2,487,54,7.02,5.5,2,"transport","membrane","protein binding;transporter activity","Pf01490","81539","ENSG00000111371.15","SLC38A1","12","GABAergic synapse; Glutamatergic synapse","Amino acid transport across the plasma membrane; Astrocytic Glutamate-Glutamine Uptake And Metabolism","Synaptic Vesicle Pathway",11,0,0.737,-0.44,0.00283576970226052,0.0724790502520929,84.2,91.5,124.3,"",46.93,24.02,134,"","",156.9,126.7,135.4,308.5,178.3,133.4,219.5,236.7,6.8,"","",125.2,95.9,107.5,223.4,128.4,133.4,178.9,188.9,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P61011","Signal recognition particle 54 kDa protein OS=Homo sapiens OX=9606 GN=SRP54 PE=1 SV=1",0,81.669,39,16,25,16,504,55.7,8.75,76.16,16,"cell organization and biogenesis;metabolic process;response to stimulus;transport","cytoplasm;cytosol;nucleus","catalytic activity;nucleotide binding;protein binding;RNA binding","Pf00448, Pf01656, Pf02881, Pf02978, Pf03205, Pf09974, Pf13207, Pf13671","6729","ENSG00000100883.11","SRP54","14","Protein export","SRP-dependent cotranslational protein targeting to membrane","mRNA Processing",5,0,1.223,0.29,0.00285716373993772,0.0729271739458698,106.1,106.7,87.3,"",10.59,6.65,5175.8,"","",5331.1,5240.3,5174.1,4200.3,4306.1,4210.8,4497.4,3831.1,262.6,"","",4254.2,3966.4,4108.7,3042,3101.4,4210.8,3665.4,3057.1,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P52298-2","Isoform 2 of Nuclear cap-binding protein subunit 2 OS=Homo sapiens OX=9606 GN=NCBP2",0,34.22,54,11,12,1,138,15.9,8.51,31.52,11,"metabolic process;regulation of biological process;response to stimulus;transport","cytoplasm;cytosol;nucleus","protein binding;RNA binding","Pf00076, Pf13893, Pf14259","22916","ENSG00000114503.10","NCBP2","3","","","mRNA Processing",1,0,0.66,-0.6,0.00288710331261388,0.0734927323027641,"",119.3,180.7,"",16.11,10.11,"","","",14.8,14.8,13.9,19.5,19.3,21.3,23.6,24.2,"","","",11.8,11.2,11,14.1,13.9,21.3,19.2,19.3,"Not Found","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P46087","Probable 28S rRNA (cytosine(4447)-C(5))-methyltransferase OS=Homo sapiens OX=9606 GN=NOP2 PE=1 SV=2",0,168.38,43,33,60,33,812,89.2,9.23,165.71,33,"cell organization and biogenesis;metabolic process;regulation of biological process","nucleus","catalytic activity;protein binding;RNA binding","Pf01189, Pf12847","4839","ENSG00000111641.11","NOP2","12","","TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation; rRNA modification in the nucleus and cytosol","Imatinib and Chronic Myeloid Leukemia",10,0,1.2,0.26,0.00291860191254623,0.0740948291991574,200.8,54.1,45.1,77.47,2.07,1.62,8465.4,32912.2,61581.1,8870.4,8968.5,8860.6,8548.4,7480.1,7426.3,7354.1,7204.6,429.5,9.2,7.8,7078.6,6788.3,7036.2,6191.1,5387.4,7426.3,5993.7,5749.1,"High","High","High","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q6JQN1","Acyl-CoA dehydrogenase family member 10 OS=Homo sapiens OX=9606 GN=ACAD10 PE=1 SV=1",0,31.896,10,9,9,9,1059,118.8,8.06,25.42,9,"metabolic process","mitochondrion;organelle lumen","catalytic activity;nucleotide binding","Pf00441, Pf00702, Pf01163, Pf01636, Pf02770, Pf02771, Pf08028, Pf13242, Pf13419","80724","ENSG00000111271.14","ACAD10","12","","Mitochondrial Fatty Acid Beta-Oxidation","",4,0,1.263,0.34,2.93324693963415E-3,0.074246025238711,104.4,109.2,86.4,"",2.49,7.26,839.6,"","",863.9,857.4,891.7,903.2,714.4,675.9,640.2,758,42.6,"","",689.4,649,708.1,654.1,514.5,675.9,521.8,604.9,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P12259","Coagulation factor V OS=Homo sapiens OX=9606 GN=F5 PE=1 SV=4",0,23.841,3,8,8,8,2224,251.5,6.05,24.38,8,"cell organization and biogenesis;coagulation;metabolic process;response to stimulus;transport","endoplasmic reticulum;extracellular;Golgi;membrane;organelle lumen","metal ion binding;protein binding","Pf00754, Pf07732","2153","ENSG00000198734.10","F5","1","Complement and coagulation cascades","Platelet degranulation ; Post-translational protein phosphorylation; Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs); Common Pathway of Fibrin Clot Formation; Cargo concentration in the ER; COPII (Coat Protein 2) Mediated Vesicle Transport","Blood Clotting Cascade; Complement and Coagulation Cascades",20,0,1.257,0.33,0.00294818114319795,0.074246025238711,91.9,115.9,92.2,"",6.86,9.12,650.4,"","",782.1,887.7,773.1,859.1,656.7,697.1,558.6,647.5,33,"","",624.1,671.9,613.9,622.2,473,697.1,455.3,516.7,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P14625","Endoplasmin OS=Homo sapiens OX=9606 GN=HSP90B1 PE=1 SV=1",0,392.809,55,54,249,52,803,92.4,4.84,731.97,54,"cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus;transport","cytosol;endoplasmic reticulum;extracellular;membrane;nucleus;organelle lumen","metal ion binding;nucleotide binding;protein binding;RNA binding","Pf00183, Pf02518, Pf13589","7184","ENSG00000166598.14","HSP90B1","12","PI3K-Akt signaling pathway; Protein processing in endoplasmic reticulum; Estrogen signaling pathway; Prostate cancer; Thyroid hormone synthesis; Pathways in cancer","Post-translational protein phosphorylation; Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs); ATF6 (ATF6-alpha) activates chaperone genes; Interleukin-4 and 13 signaling; Trafficking and processing of endosomal TLR; Scavenging by Class A Receptors","Photodynamic therapy-induced unfolded protein response; Focal Adhesion-PI3K-Akt-mTOR-signaling pathway; Sudden Infant Death Syndrome (SIDS) Susceptibility Pathways",26,0,1.199,0.26,2.972068940577E-3,0.0746495188159819,125,95.4,79.6,40.36,3.73,1.31,23701.1,"",42633.1,24787.2,23781.9,25281.6,23304.1,20534.9,20298.2,19897.3,20193.4,1202.5,"",5.4,19780.3,18000.5,20076,16877.8,14789.8,20298.2,16216.5,16113.8,"High","High","High","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q6P444","Mitochondrial fission regulator 2 OS=Homo sapiens OX=9606 GN=MTFR2 PE=1 SV=2",0,5.574,6,2,2,2,385,43.4,7.01,7.37,2,"cell organization and biogenesis;metabolic process","mitochondrion","protein binding","Pf05308","113115","ENSG00000146410.11","FAM54A; MTFR2","6","","","",0,0,0.719,-0.48,0.00317743605163656,0.0795960373253467,"",125.5,174.5,"",10.2,9.88,"","","",68.5,57.3,54.3,60.8,86.8,77.6,73.1,90.7,"","","",54.7,43.4,43.1,44,62.5,77.6,59.6,72.4,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q53SF7","Cordon-bleu protein-like 1 OS=Homo sapiens OX=9606 GN=COBLL1 PE=1 SV=3",0,129.478,28,21,30,21,1128,123.8,6.58,112.55,21,"","","","","","","","","","","",0,0,1.26,0.33,0.00325336094330675,0.081067917542451,166.7,74.3,59,86.55,6.68,3.87,2497.2,10374.5,"",2226.7,2315.2,2314.2,2001.5,1692.1,1851.5,1821.6,1782.8,126.7,2.9,"",1776.9,1752.4,1837.7,1449.6,1218.7,1851.5,1484.6,1422.6,"High","High","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P62745","Rho-related GTP-binding protein RhoB OS=Homo sapiens OX=9606 GN=RHOB PE=1 SV=1",0,22.541,30,6,6,6,196,22.1,5.24,15.35,6,"cell death;cell differentiation;development;regulation of biological process;response to stimulus;transport","cytosol;endosome;membrane;nucleus","catalytic activity;nucleotide binding;protein binding","Pf00025, Pf00071, Pf08477","388","ENSG00000143878.9","RHOB","2","","G alpha (12/13) signalling events; RHO GTPases Activate ROCKs; GPVI-mediated activation cascade; Sema4D induced cell migration and growth-cone collapse; Rho GTPase cycle; RHO GTPases Activate Formins; RHO GTPases activate CIT; RHO GTPases activate PKNs; RHO GTPases Activate Rhotekin and Rhophilins","Androgen receptor signaling pathway; Neural Crest Differentiation; Spinal Cord Injury; Focal Adhesion",24,0,0.817,-0.29,3.24667415716773E-3,0.081067917542451,169.3,58.7,71.9,105.22,8.82,6.09,1470.4,10016.8,"",1259,1256.8,1407.3,1501.2,1580.2,1497,1681.8,1712.8,74.6,2.8,"",1004.7,951.3,1117.5,1087.2,1138.1,1497,1370.7,1366.8,"High","High","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q9Y6H1","Coiled-coil-helix-coiled-coil-helix domain-containing protein 2 OS=Homo sapiens OX=9606 GN=CHCHD2 PE=1 SV=1",0,40.228,38,4,11,4,151,15.5,9.22,40.76,4,"cell organization and biogenesis;metabolic process;regulation of biological process","mitochondrion;nucleus","DNA binding;protein binding","Pf06747","51142","ENSG00000106153.12","CHCHD2","7","","Mitochondrial protein import; Metabolism of proteins","",2,0,0.787,-0.35,0.00329718445814509,0.0817812644150765,78.3,97.6,124.1,"",1.34,1.08,480.9,"","",605.3,589.6,605.2,593.7,758.9,768.3,765,749.6,24.4,"","",483,446.3,480.6,430,546.6,768.3,623.5,598.2,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P17936","Insulin-like growth factor-binding protein 3 OS=Homo sapiens OX=9606 GN=IGFBP3 PE=1 SV=2",0.007,2.671,4,1,1,1,291,31.7,8.69,2.1,1,"cell death;cell differentiation;cell proliferation;metabolic process;regulation of biological process","extracellular;nucleus;organelle lumen","enzyme regulator activity;metal ion binding;protein binding","Pf00086, Pf00219","3486","ENSG00000146674.14","IGFBP3","7","p53 signaling pathway; Transcriptional misregulation in cancer","TP53 Regulates Transcription of Death Receptors and Ligands; Post-translational protein phosphorylation; Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)","Myometrial Relaxation and Contraction Pathways; Photodynamic therapy-induced HIF-1 survival signaling; Senescence and Autophagy in Cancer",15,0,0.662,-0.6,3.29444682767743E-3,0.0817812644150765,"",119.5,180.5,"",15.12,12.33,"","","",12.8,11.4,15.5,15.6,23.6,19.8,22.8,18,"","","",10.2,8.6,12.3,11.3,17,19.8,18.6,14.4,"Not Found","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P16070","CD44 antigen OS=Homo sapiens OX=9606 GN=CD44 PE=1 SV=3",0,171.489,18,16,63,16,742,81.5,5.33,207.86,16,"cell organization and biogenesis;cellular component movement;metabolic process;regulation of biological process;response to stimulus;transport","cell surface;cytosol;Golgi;membrane","protein binding;receptor activity;signal transducer activity","Pf00193","960","ENSG00000026508.17","CD44","11","Epstein-Barr virus infection; Shigellosis; Hematopoietic cell lineage; Proteoglycans in cancer; MicroRNAs in cancer; ECM-receptor interaction","Integrin cell surface interactions; Degradation of the extracellular matrix; Neutrophil degranulation; Hyaluronan uptake and degradation; Interferon gamma signaling; Cell surface interactions at the vascular wall","Hepatitis C and Hepatocellular Carcinoma; Wnt Signaling Pathway and Pluripotency; Senescence and Autophagy in Cancer",25,0,1.196,0.26,3.46015173647096E-3,0.0830436416753031,106.4,105.4,88.1,8.92,4.21,5.42,8828,10016.8,"",9054.7,9576.3,8886.3,9690.1,7441.8,8069.2,7515.1,8314,447.9,2.8,"",7225.7,7248.3,7056.6,7018,5359.8,8069.2,6124.9,6634.4,"High","High","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q86U06-2","Isoform 2 of Probable RNA-binding protein 23 OS=Homo sapiens OX=9606 GN=RBM23",0,11.369,9,2,3,2,423,46.7,9.26,11.7,2,"metabolic process","membrane;nucleus","protein binding;RNA binding","Pf00076, Pf13893, Pf14259, Pf15519","55147","ENSG00000100461.17","RBM23","14","","","",0,0,0.691,-0.53,3.44469111128998E-3,0.0830436416753031,"",122.6,177.4,"",11.86,5.24,"","","",26.6,34,33,28.2,44.3,43.9,47.5,41.9,"","","",21.2,25.7,26.2,20.4,31.9,43.9,38.7,33.4,"Not Found","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"Medium","Master Protein","Q00013","55 kDa erythrocyte membrane protein OS=Homo sapiens OX=9606 GN=MPP1 PE=1 SV=2",0.014,2.189,3,2,2,2,466,52.3,7.37,4.68,2,"metabolic process;regulation of biological process;response to stimulus","cytoskeleton;membrane","catalytic activity;protein binding","Pf00018, Pf00595, Pf00625, Pf07653, Pf13180, Pf14604","4354","ENSG00000130830.14","MPP1","X","","","Mecp2 and Associated Rett Syndrome",1,0,0.76,-0.4,0.00344027118776902,0.0830436416753031,98.4,87,114.6,"",16.48,4.19,297.6,"","",263.7,262.8,248.8,350.2,368.2,342.7,350.4,333.8,15.1,"","",210.4,198.9,197.6,253.6,265.2,342.7,285.6,266.4,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q03154","Aminoacylase-1 OS=Homo sapiens OX=9606 GN=ACY1 PE=1 SV=1",0,61.908,40,15,21,15,408,45.9,6.18,58.93,15,"metabolic process","cytoplasm;cytosol","catalytic activity;metal ion binding;protein binding","Pf01546, Pf07687","95","ENSG00000243989.8","ACY1","3","2-Oxocarboxylic acid metabolism; Metabolic pathways; Arginine biosynthesis; Biosynthesis of amino acids","Defective ACY1 causes encephalopathy; Aflatoxin activation and detoxification","Urea cycle and metabolism of amino groups",12,0,1.24,0.31,0.00350149762051966,0.0839292982948925,199.1,55.8,45,122.8,3.94,5.4,2448,"",34738,2574.5,2484.5,2597.2,2732.2,2023.9,1971.3,2147.6,2218.1,124.2,"",4.4,2054.5,1880.5,2062.4,1978.8,1457.7,1971.3,1750.3,1770,"High","Not Found","High","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","O00311","Cell division cycle 7-related protein kinase OS=Homo sapiens OX=9606 GN=CDC7 PE=1 SV=1",0,32.624,18,8,8,8,574,63.8,8.73,18.73,8,"cell division;metabolic process;regulation of biological process;response to stimulus;transport","cytoplasm;nucleus","catalytic activity;metal ion binding;nucleotide binding;protein binding","Pf00069, Pf01636, Pf07714","8317","ENSG00000097046.12","CDC7","1","Cell cycle","M/G1 Transition; Activation of ATR in response to replication stress; Transcriptional Regulation by E2F6; Activation of the pre-replicative complex","Cell Cycle; Retinoblastoma (RB) in Cancer; DNA Replication",19,0,0.788,-0.34,3.67938540245283E-3,0.0873304324563738,81.2,96.4,122.3,"",7.69,3.66,512.5,"","",574.8,628.9,589,681,811.3,778.4,765.6,743.4,26,"","",458.7,476,467.7,493.2,584.3,778.4,624,593.2,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P0DPD7","EEF1A lysine methyltransferase 4 OS=Homo sapiens OX=9606 GN=EEF1AKMT4 PE=1 SV=1",0,18.019,24,6,6,6,255,28.3,6.05,15.25,6,"","","","","","","","","","","",0,0,1.247,0.32,0.0036850039531835,0.0873304324563738,112.7,103.9,83.4,"",14.25,7.13,758.8,"","",712.4,695.7,703.6,517.1,537.2,590.4,586.4,508.5,38.5,"","",568.5,526.6,558.7,374.5,386.9,590.4,477.9,405.8,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q8N9R8","Protein SCAI OS=Homo sapiens OX=9606 GN=SCAI PE=1 SV=2",0,11.883,8,5,5,5,606,70.4,8.6,12.34,5,"metabolic process;regulation of biological process","cytoplasm;membrane;nucleus","protein binding","Pf12070","286205","ENSG00000173611.17","SCAI","9","","RHO GTPases Activate Formins","",4,0,0.763,-0.39,0.00368162619004653,0.0873304324563738,82.3,94.2,123.5,"",6.55,3.22,256.2,"","",309.3,289.7,297.2,264.3,384,385.3,406.4,377.6,13,"","",246.8,219.3,236,191.4,276.6,385.3,331.2,301.3,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q16850","Lanosterol 14-alpha demethylase OS=Homo sapiens OX=9606 GN=CYP51A1 PE=1 SV=3",0,73.202,31,14,22,14,503,56.8,8.53,83.94,14,"metabolic process;regulation of biological process","endoplasmic reticulum;membrane","catalytic activity;metal ion binding","Pf00067","1595","","CYP51A1","7","Steroid biosynthesis; Metabolic pathways","Cholesterol biosynthesis; Endogenous sterols; Activation of gene expression by SREBF (SREBP)","Cholesterol Biosynthesis; Sterol Regulatory Element-Binding Proteins (SREBP) signalling; Oxidation by Cytochrome P450; Metapathway biotransformation",16,0,1.22,0.29,3.70295665964893E-3,0.0876459215381565,183.1,64.2,52.6,106.75,6.93,3.14,3419.7,"",24474.5,3400,3033.3,3391.5,2991.1,2637.5,2654.7,2621.4,2477,173.5,"",3.1,2713.2,2295.9,2693.2,2166.3,1899.6,2654.7,2136.5,1976.6,"High","Not Found","High","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","O95633","Follistatin-related protein 3 OS=Homo sapiens OX=9606 GN=FSTL3 PE=1 SV=1",0,14.136,18,4,4,4,263,27.6,6.77,12.15,4,"cell differentiation;metabolic process;regulation of biological process;response to stimulus","extracellular;Golgi;nucleus;organelle lumen","protein binding","Pf00050, Pf07648","10272","ENSG00000070404.9","FSTL3","19","","Post-translational protein phosphorylation; Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs); Antagonism of Activin by Follistatin","",8,0,0.75,-0.41,3.75228499858249E-3,0.0885914488165326,106,83.2,110.9,"",5.56,8.17,220.8,"","",178.3,166.1,168.4,187.2,249.2,220,242.6,209.2,11.2,"","",142.3,125.7,133.7,135.6,179.5,220,197.7,166.9,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q14240","Eukaryotic initiation factor 4A-II OS=Homo sapiens OX=9606 GN=EIF4A2 PE=1 SV=2",0,141.655,45,24,76,9,407,46.4,5.48,207.37,24,"metabolic process;regulation of biological process","cytosol","catalytic activity;DNA binding;nucleotide binding;protein binding;RNA binding","Pf00270, Pf00271, Pf04851","1974","ENSG00000156976.16","EIF4A2","3","RNA transport","ISG15 antiviral mechanism; L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; GTP hydrolysis and joining of the 60S ribosomal subunit; Deadenylation of mRNA; Ribosomal scanning and start codon recognition","Translation Factors",19,0,0.823,-0.28,0.00383067873106091,0.090166976068849,98.2,91.1,110.7,"",2.86,8.62,2118.8,"","",1935.5,2023.6,1898.5,1992.4,2272.3,2443.2,2332.5,2747,107.5,"","",1544.5,1531.7,1507.6,1443,1636.6,2443.2,1901,2192,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q5T8I3","Protein FAM102B OS=Homo sapiens OX=9606 GN=FAM102B PE=1 SV=2",0,80.298,46,15,15,15,360,39.3,7.02,55.77,15,"","","","Pf10358","284611","ENSG00000162636.15","FAM102B","1","","","",0,0,0.82,-0.29,0.00402861626113693,0.0942905872866844,105.9,87.4,106.6,"",5.69,2.01,2428.3,"","",2142.7,1914.5,2085.5,1924.6,2435.5,2369.8,2486.2,2453.5,123.2,"","",1709.9,1449.1,1656.1,1393.9,1754.1,2369.8,2026.3,1957.8,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q8WXH0","Nesprin-2 OS=Homo sapiens OX=9606 GN=SYNE2 PE=1 SV=3",0,405.386,17,116,127,116,6885,795.9,5.36,369.75,116,"cell organization and biogenesis;cellular component movement;regulation of biological process;transport","cytoplasm;cytoskeleton;endoplasmic reticulum;membrane;mitochondrion;nucleus;organelle lumen","protein binding","Pf00307, Pf00435, Pf10541, Pf11971, Pf13654","23224","ENSG00000054654.16","SYNE2","14","","Meiotic synapsis","Ovarian Infertility Genes",5,0,0.838,-0.25,0.00405459467381841,0.0946640101348358,114.9,84.4,100.7,45.19,4.44,4.9,10515.2,20391.3,"",10609.6,10564.7,10902.6,11615.9,12801.2,12854.1,12706.2,14065.1,533.5,5.7,"",8466.5,7996.4,8657.7,8412.7,9219.8,12854.1,10355.7,11223.6,"High","High","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q01105","Protein SET OS=Homo sapiens OX=9606 GN=SET PE=1 SV=3",0,53.653,29,7,26,1,290,33.5,4.32,86.58,7,"cell organization and biogenesis;metabolic process;regulation of biological process;transport","cytoplasm;cytosol;endoplasmic reticulum;nucleus","DNA binding;enzyme regulator activity;protein binding","Pf00956","6418","ENSG00000119335.16","SET","9","","HuR (ELAVL1) binds and stabilizes mRNA; Condensation of Prophase Chromosomes","Histone Modifications",9,7,0.824,-0.28,0.00406325512118944,0.0947490897889211,91.4,94.2,114.4,"",8.53,8.21,3348.7,"","",3667.1,3247.7,3244.8,3832.1,3988.6,3855.7,4400.3,4594,169.9,"","",2926.4,2458.2,2576.7,2775.4,2872.7,3855.7,3586.3,3665.9,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","O43795","Unconventional myosin-Ib OS=Homo sapiens OX=9606 GN=MYO1B PE=1 SV=3",0,99.461,18,20,29,20,1136,131.9,9.38,90.18,20,"cell organization and biogenesis;cellular component movement;transport","cytoplasm;endosome;membrane","catalytic activity;motor activity;nucleotide binding;protein binding","Pf00063, Pf06017","4430","ENSG00000128641.18","MYO1B","2","","","",0,0,1.207,0.27,0.00409781057229019,0.0949532972348405,142.3,86.3,71.5,67.57,6.97,3.65,3792.2,10732.2,"",3905.9,3844.6,3891.2,3360.6,3277.6,3300.4,3134.3,3056.4,192.4,3,"",3116.9,2910,3090,2433.9,2360.6,3300.4,2554.5,2438.9,"High","High","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q5T5Y3","Calmodulin-regulated spectrin-associated protein 1 OS=Homo sapiens OX=9606 GN=CAMSAP1 PE=1 SV=2",0,66.952,11,18,20,18,1602,177.9,6.73,55.67,18,"cell organization and biogenesis;regulation of biological process","cytoplasm;cytoskeleton","protein binding","Pf00307, Pf08683, Pf11971","157922","ENSG00000130559.18","CAMSAP1","9","","","",0,0,0.822,-0.28,0.0041323433177376,0.095417726877051,91,94.3,114.7,"",2.64,5.77,1645.8,"","",1776.8,1716.3,1671.3,1694.2,2181.3,2081.9,2064.9,1895.5,83.5,"","",1417.9,1299.1,1327.2,1227,1571,2081.9,1682.9,1512.6,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P07951","Tropomyosin beta chain OS=Homo sapiens OX=9606 GN=TPM2 PE=1 SV=1",0,118.078,53,23,80,2,284,32.8,4.7,232.78,23,"cell organization and biogenesis;cellular component movement;regulation of biological process","cytoplasm;cytoskeleton;cytosol","protein binding;structural molecule activity","Pf00261, Pf12718","7169","ENSG00000198467.13","TPM2","9","Hypertrophic cardiomyopathy (HCM); Adrenergic signaling in cardiomyocytes; Cardiac muscle contraction; Dilated cardiomyopathy","Smooth Muscle Contraction; Striated Muscle Contraction","Striated Muscle Contraction",8,0,0.751,-0.41,0.00413835422682363,0.0954398469307016,99.3,86.1,114.6,"",15.13,19.61,199.1,"","",140.6,168.8,176.2,204.1,254.5,220.5,239.1,157.3,10.1,"","",112.2,127.8,139.9,147.8,183.3,220.5,194.9,125.5,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P19021","Peptidyl-glycine alpha-amidating monooxygenase OS=Homo sapiens OX=9606 GN=PAM PE=1 SV=2",1E-3,4.94,2,2,2,2,973,108.3,6.42,5.43,2,"cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus;transport","cell surface;extracellular;membrane","catalytic activity;metal ion binding;protein binding","Pf01082, Pf01436, Pf03712","5066","ENSG00000145730.20","PAM","5","","","",0,0,1.337,0.42,0.00418205606173427,0.0955956151902937,93.1,118.4,88.5,"",3.76,11.03,94.6,"","",123.3,126.4,117.4,117.2,91.1,108.4,88.8,85.2,4.8,"","",98.4,95.7,93.2,84.9,65.6,108.4,72.4,68,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P28300","Protein-lysine 6-oxidase OS=Homo sapiens OX=9606 GN=LOX PE=1 SV=2",0,23.825,16,4,4,4,417,46.9,8.09,14.07,4,"cell organization and biogenesis;metabolic process;response to stimulus","extracellular;nucleus","catalytic activity;metal ion binding;protein binding","Pf01186","4015","ENSG00000113083.13","LOX","5","","Elastic fibre formation; Crosslinking of collagen fibrils","Canonical and Non-Canonical TGF-B signaling",6,0,1.34,0.42,0.00419091900793522,0.0956015437462325,"",171.8,128.2,"",15.23,11.37,"","","",101.3,77.8,99.2,76.1,67.6,72.7,63.6,55.3,"","","",80.8,58.9,78.8,55.1,48.7,72.7,51.8,44.1,"Not Found","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","O43683","Mitotic checkpoint serine/threonine-protein kinase BUB1 OS=Homo sapiens OX=9606 GN=BUB1 PE=1 SV=1",0,23.522,7,7,7,7,1085,122.3,6.47,19.05,7,"cell death;cell division;cell organization and biogenesis;cell proliferation;metabolic process;regulation of biological process","chromosome;cytosol;membrane;nucleus","catalytic activity;nucleotide binding;protein binding","Pf00069, Pf08311","699","ENSG00000169679.14","BUB1","2","Cell cycle; Progesterone-mediated oocyte maturation; Oocyte meiosis","Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal; Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins","Cell Cycle; ATM Signaling Network in Development and Disease",21,0,0.754,-0.41,0.00421008241038479,0.0956919814288181,61.7,102.5,135.9,"",9.87,3.21,122.2,"","",203.4,189.7,202.7,237.8,269.4,269.3,259.1,280.3,6.2,"","",162.3,143.6,161,172.2,194,269.3,211.2,223.7,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q96FQ6","Protein S100-A16 OS=Homo sapiens OX=9606 GN=S100A16 PE=1 SV=1",0,32.939,54,5,14,5,103,11.8,6.79,36.59,5,"response to stimulus","cytoplasm;cytosol;membrane;nucleus","metal ion binding;protein binding;RNA binding","Pf01023, Pf13202, Pf13499, Pf13833","140576","ENSG00000188643.10","S100A16","1","","","",0,0,1.235,0.3,0.00435084074693082,0.098772451956766,102.8,108.9,88.2,"",3.54,2.01,1813.3,"","",1937.6,1916.4,1793.6,1925.3,1573.7,1537.9,1511,1576.2,92,"","",1546.2,1450.5,1424.3,1394.4,1133.4,1537.9,1231.5,1257.8,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q16401","26S proteasome non-ATPase regulatory subunit 5 OS=Homo sapiens OX=9606 GN=PSMD5 PE=1 SV=3",0,84.554,40,17,25,17,504,56.2,5.48,80.94,17,"cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus;transport","cytosol;proteasome","protein binding","Pf10508","5711","ENSG00000095261.13","PSMD5","9","","Regulation of RAS by GAPs; CDT1 association with the CDC6:ORC:origin complex; Downstream TCR signaling; UCH proteinases; NIK-->noncanonical NF-kB signaling; Hh mutants that don't undergo autocatalytic processing are degraded by ERAD; SCF-beta-TrCP mediated degradation of Emi1; Cross-presentation of soluble exogenous antigens (endosomes); Separation of Sister Chromatids; Vpu mediated degradation of CD4; Hedgehog ligand biogenesis; Regulation of RUNX2 expression and activity; Ub-specific processing proteases; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; ER-Phagosome pathway; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; ABC-family proteins mediated transport; Regulation of activated PAK-2p34 by proteasome mediated degradation; CDK-mediated phosphorylation and removal of Cdc6; FCERI mediated NF-kB activation; Neddylation; Autodegradation of the E3 ubiquitin ligase COP1; G2/M Checkpoints; Regulation of RUNX3 expression and activity; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Regulation of expression of SLITs and ROBOs; Removal of licensing factors from origins; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; Regulation of PTEN stability and activity; Regulation of DNA replication; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; Vif-mediated degradation of APOBEC3G; Antigen processing: Ubiquitination & Proteasome degradation; GLI3 is processed to GLI3R by the proteasome; SCF(Skp2)-mediated degradation of p27/p21; APC/C:Cdc20 mediated degradation of Securin; Interleukin-1 family signaling; AUF1 (hnRNP D0) binds and destabilizes mRNA; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; The role of GTSE1 in G2/M progression after G2 checkpoint; Regulation of ornithine decarboxylase (ODC); Interleukin-20 family signaling; Hedgehog 'on' state; Ubiquitin-dependent degradation of Cyclin D1; Degradation of DVL; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Degradation of AXIN; Autodegradation of Cdh1 by Cdh1:APC/C; Asymmetric localization of PCP proteins; Orc1 removal from chromatin; M/G1 Transition; Activation of NF-kappaB in B cells; Degradation of beta-catenin by the destruction complex; MAPK6/MAPK4 signaling; Dectin-1 mediated noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosis","Proteasome Degradation; Parkin-Ubiquitin Proteasomal System pathway",150,0,0.825,-0.28,0.00438977841916821,0.0990610929286131,98.9,90.9,110.2,"",4.15,2.17,3796.1,"","",3539.7,3539,3443.2,3236.6,4208.3,4077.3,4281.9,4257.5,192.6,"","",2824.7,2678.7,2734.2,2344.1,3030.9,4077.3,3489.8,3397.4,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P01889","HLA class I histocompatibility antigen, B alpha chain OS=Homo sapiens OX=9606 GN=HLA-B PE=1 SV=3",0,69.164,25,9,19,4,362,40.4,5.85,61.69,9,"regulation of biological process;response to stimulus;transport","cell surface;endoplasmic reticulum;Golgi;membrane","protein binding","Pf00129, Pf06623, Pf07654","3106","ENSG00000234745.10","HLA-B","6","Type I diabetes mellitus; Endocytosis; Viral myocarditis; Phagosome; Cell adhesion molecules (CAMs); Allograft rejection; Antigen processing and presentation; Herpes simplex infection; HTLV-I infection; Graft-versus-host disease; Autoimmune thyroid disease; Natural killer cell mediated cytotoxicity; Epstein-Barr virus infection; Viral carcinogenesis","Interferon alpha/beta signaling; ER-Phagosome pathway; Neutrophil degranulation; Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell; Endosomal/Vacuolar pathway; Interferon gamma signaling; Antigen Presentation: Folding, assembly and peptide loading of class I MHC","Proteasome Degradation; Allograft Rejection; Type II interferon signaling (IFNG)",31,0,0.79,-0.34,0.00440079856598752,0.0990730432829228,81.3,96.5,122.2,"",2.3,10.76,400.1,"","",467.5,462.1,482.2,484.4,493.6,588.5,614,636.1,20.3,"","",373.1,349.8,382.9,350.8,355.5,588.5,500.4,507.6,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P61916","NPC intracellular cholesterol transporter 2 OS=Homo sapiens OX=9606 GN=NPC2 PE=1 SV=1",0,35.104,35,5,15,5,151,16.6,7.65,48.73,5,"metabolic process;regulation of biological process;response to stimulus;transport","endoplasmic reticulum;extracellular;organelle lumen;vacuole","protein binding;transporter activity","Pf02221","10577","ENSG00000119655.10","NPC2","14","Lysosome","Neutrophil degranulation; LDL clearance","TYROBP Causal Network",9,0,1.246,0.32,0.00441953174807663,0.0993763281638946,112,104.3,83.7,"",2.62,3.84,3003.8,"","",2864.9,2767.5,2824,2696.3,2300.4,2323.2,2189.9,2144.7,152.4,"","",2286.2,2094.7,2242.5,1952.8,1656.8,2323.2,1784.8,1711.4,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q16610","Extracellular matrix protein 1 OS=Homo sapiens OX=9606 GN=ECM1 PE=1 SV=2",0,36.239,14,5,6,5,540,60.6,6.71,25.29,5,"defense response;regulation of biological process;response to stimulus;transport","extracellular;organelle lumen","protein binding;signal transducer activity","Pf05782, Pf09770","1893","ENSG00000143369.14","ECM1","1","","Platelet degranulation","",4,0,1.262,0.34,0.00448493507703396,0.10057492424798,117,102.1,80.9,"",5.88,5.81,611,"","",528.7,488.2,563,538.2,408.5,464.9,416.3,429.3,31,"","",421.9,369.5,447.1,389.8,294.2,464.9,339.3,342.6,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","L0R819","ASNSD1 upstream open reading frame protein OS=Homo sapiens OX=9606 GN=ASDURF PE=1 SV=1",0,16.613,41,3,4,3,96,11.2,8.88,13.36,3,"","","","","110599588","ENSG00000138381.9","ASDURF","2","","","",0,0,1.306,0.39,0.00448937660476734,0.10057492424798,105.6,110.1,84.3,"",13.69,6.53,214.8,"","",220.9,244.2,227.4,174.8,179.4,167.3,176.1,154.6,10.9,"","",176.3,184.8,180.6,126.6,129.2,167.3,143.5,123.4,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q9H0W9","Ester hydrolase C11orf54 OS=Homo sapiens OX=9606 GN=C11orf54 PE=1 SV=1",0,27.369,7,1,5,1,315,35.1,6.7,27.91,1,"","nucleus","catalytic activity;metal ion binding;protein binding","Pf08925","28970","ENSG00000182919.14","C11orf54","11","","","",0,0,0.732,-0.45,0.00462284299075955,0.10296728586022,"",126.8,173.2,"",10.01,7.86,"","","",57.3,53.5,45,50.9,68.9,73.9,80.7,68.4,"","","",45.7,40.5,35.7,36.9,49.6,73.9,65.8,54.6,"Not Found","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q92990","Glomulin OS=Homo sapiens OX=9606 GN=GLMN PE=1 SV=2",0,22.188,12,6,8,6,594,68.2,5.33,22.25,6,"cell differentiation;regulation of biological process","cytoplasm","enzyme regulator activity;protein binding","Pf08568","11146","ENSG00000174842.16","GLMN","1","","Antigen processing: Ubiquitination & Proteasome degradation","",4,0,0.8,-0.32,0.00464353706381071,0.103306393476156,98,89.8,112.2,"",32.5,14.68,737.1,"","",646.7,643.1,704.1,1177,820.7,634.4,898.3,866.9,37.4,"","",516.1,486.8,559.1,852.4,591.1,634.4,732.1,691.8,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P35232","Prohibitin OS=Homo sapiens OX=9606 GN=PHB PE=1 SV=1",0,118.741,58,19,65,19,272,29.8,5.76,187.77,19,"cell differentiation;cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus;transport","cell surface;cytoplasm;endosome;membrane;mitochondrion;nucleus","DNA binding;protein binding","Pf01145","5245","ENSG00000167085.11","PHB","17","","Paradoxical activation of RAF signaling by kinase inactive BRAF; Processing of SMDT1; RAF activation; Signaling by RAS mutants; Signaling by moderate kinase activity BRAF mutants; Interleukin-20 family signaling","Integrated Breast Cancer Pathway",19,0,1.188,0.25,0.00474620531097747,0.105466265780873,146.2,83.5,70.3,77.06,4.37,4.08,9062.6,30765.8,"",9570.5,9509.2,9647.3,8764.3,8685.4,8023.7,8029.8,7999.5,459.8,8.6,"",7637.3,7197.5,7660.9,6347.5,6255.5,8023.7,6544.4,6383.4,"High","High","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P49842","Serine/threonine-protein kinase 19 OS=Homo sapiens OX=9606 GN=STK19 PE=1 SV=2",0,6.255,6,2,3,2,368,40.9,9.74,8.43,2,"metabolic process","nucleus","catalytic activity;nucleotide binding","Pf10494","8859","ENSG00000234947.8; ENSG00000226257.9; ENSG00000226033.9; ENSG00000236250.8; ENSG00000204344.14","STK19","6; CHR_HSCHR6_MHC_COX_CTG1; CHR_HSCHR6_MHC_DBB_CTG1; CHR_HSCHR6_MHC_MCF_CTG1; CHR_HSCHR6_MHC_SSTO_CTG1","","","",0,0,0.704,-0.51,0.0047947549359717,0.106046055305191,"",124,176,"",12.73,6.51,"","","",32.3,40.8,33.9,30.9,45.3,48.8,43.4,50,"","","",25.8,30.9,26.9,22.4,32.6,48.8,35.4,39.9,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q16706","Alpha-mannosidase 2 OS=Homo sapiens OX=9606 GN=MAN2A1 PE=1 SV=2",0,51.235,11,10,12,10,1144,131.1,7.58,35.5,10,"cell organization and biogenesis;metabolic process;regulation of biological process","Golgi;membrane","catalytic activity;metal ion binding","Pf01074, Pf07748, Pf09261","4124","ENSG00000112893.9","MAN2A1","5","Metabolic pathways; N-Glycan biosynthesis","Intra-Golgi traffic; Reactions specific to the complex N-glycan synthesis pathway","",12,0,1.257,0.33,0.00483671019766785,0.106724044641998,108,106.9,85.1,"",4.34,5.45,1190.5,"","",1126.4,1231.5,1144.8,1213.1,982.1,975.9,882.6,901,60.4,"","",898.9,932.1,909.1,878.6,707.3,975.9,719.3,719,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q14393","Growth arrest-specific protein 6 OS=Homo sapiens OX=9606 GN=GAS6 PE=1 SV=3",0,13.465,7,6,6,6,678,74.9,5.69,16.57,6,"","","","","","","","","","","",0,0,1.322,0.4,0.00488069938456626,0.107443647990312,107.7,109.5,82.8,"",10.22,7.07,191.2,"","",192.6,157.4,196.2,196.6,154.5,135.4,155.9,139.9,9.7,"","",153.7,119.1,155.8,142.4,111.3,135.4,127.1,111.6,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q9UHB6","LIM domain and actin-binding protein 1 OS=Homo sapiens OX=9606 GN=LIMA1 PE=1 SV=1",0,208.2,48,33,68,1,759,85.2,6.84,229.02,33,"cell organization and biogenesis;regulation of biological process","cytoplasm;cytoskeleton","metal ion binding;protein binding","Pf00412","51474","ENSG00000050405.13","LIMA1","12","","","",0,33,0.842,-0.25,0.00489994321683462,0.107741708358059,93.7,94.3,112,"",7.77,3.58,7860.3,"","",7585.6,8154.3,7676.5,8960.8,8829.6,9549.6,9285.3,9519.5,398.8,"","",6053.3,6172,6095.9,6489.8,6359.3,9549.6,7567.6,7596.3,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P27816-5","Isoform 5 of Microtubule-associated protein 4 OS=Homo sapiens OX=9606 GN=MAP4",0,172.161,37,26,56,1,809,85.2,7.71,167.55,26,"cell division;cell organization and biogenesis;cellular component movement;regulation of biological process","cytoplasm","protein binding;RNA binding;structural molecule activity","Pf00418","4134","","MAP4","3","","","",0,0,0.769,-0.38,0.00492058869930201,0.107944343034165,77.3,96.8,125.9,"",11.62,15.5,185.3,"","",232.7,231.5,248.3,187.5,244.8,275.3,331.2,342.4,9.4,"","",185.7,175.2,197.2,135.8,176.3,275.3,269.9,273.2,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q96F07-2","Isoform 2 of Cytoplasmic FMR1-interacting protein 2 OS=Homo sapiens OX=9606 GN=CYFIP2",0,57.534,13,15,18,5,1253,145.6,7.05,53.83,15,"cell death;cell growth;metabolic process;regulation of biological process;response to stimulus","cytoplasm;cytosol;membrane;nucleus","protein binding","Pf05994, Pf07159","26999","ENSG00000055163.19","CYFIP2","5","","","Regulation of Actin Cytoskeleton",1,0,1.241,0.31,0.00497423332659497,0.108506652308732,101.4,110,88.6,"",6.82,2.43,616.9,"","",701.2,651.3,686.6,600.1,563.2,534,539.3,538.2,31.3,"","",559.6,493,545.2,434.6,405.6,534,439.5,429.5,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q9H7Z7","Prostaglandin E synthase 2 OS=Homo sapiens OX=9606 GN=PTGES2 PE=1 SV=1",0,56.829,43,14,21,14,377,41.9,9.16,64.01,14,"cellular homeostasis;metabolic process;regulation of biological process;transport","cytoplasm;cytosol;extracellular;Golgi;membrane;mitochondrion;nucleus;organelle lumen","catalytic activity;DNA binding;protein binding","Pf00043, Pf00462, Pf13409, Pf13410, Pf13417, Pf14497","80142","ENSG00000148334.14","PTGES2","9","Arachidonic acid metabolism; Metabolic pathways","Synthesis of Prostaglandins (PG) and Thromboxanes (TX); Neutrophil degranulation","Eicosanoid Synthesis",11,0,0.826,-0.28,0.00497458019892938,0.108506652308732,88.2,95.8,116,"",7.41,3.35,1994.6,"","",2250.6,2145.6,2191.4,1893.4,2630.6,2648.1,2619.3,2460.6,101.2,"","",1796,1624,1740.2,1371.3,1894.6,2648.1,2134.8,1963.5,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q8NI37","Protein phosphatase PTC7 homolog OS=Homo sapiens OX=9606 GN=PPTC7 PE=1 SV=1",0,25.98,19,5,6,5,304,32.6,5.19,23.4,5,"metabolic process","mitochondrion","catalytic activity;metal ion binding","Pf00481, Pf07228","160760","ENSG00000196850.5","PPTC7","12","","","",0,0,1.307,0.39,0.00510630590494299,0.110859661991452,100.9,112.8,86.3,"",2.35,7.93,317.3,"","",360,359.9,349.6,343.1,277.1,265.8,259.6,309.2,16.1,"","",287.3,272.4,277.6,248.5,199.6,265.8,211.6,246.7,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q13509","Tubulin beta-3 chain OS=Homo sapiens OX=9606 GN=TUBB3 PE=1 SV=2",0,239.762,41,22,156,3,450,50.4,4.93,322.09,22,"cell organization and biogenesis;cellular component movement","cytoplasm;cytoskeleton;nucleus","catalytic activity;nucleotide binding;protein binding;structural molecule activity","Pf00091, Pf03953, Pf10644","10381","ENSG00000258947.6","TUBB3","16","Gap junction; Phagosome; Pathogenic Escherichia coli infection","COPI-independent Golgi-to-ER retrograde traffic; COPI-dependent Golgi-to-ER retrograde traffic; Carboxyterminal post-translational modifications of tubulin; Recruitment of NuMA to mitotic centrosomes; Hedgehog 'off' state; Translocation of GLUT4 to the plasma membrane; Prefoldin mediated transfer of substrate  to CCT/TriC; Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane; Separation of Sister Chromatids; COPI-mediated anterograde transport; HSP90 chaperone cycle for steroid hormone receptors (SHR); The role of GTSE1 in G2/M progression after G2 checkpoint; Kinesins; Formation of tubulin folding intermediates by CCT/TriC; RHO GTPases activate IQGAPs; Recycling pathway of L1; Resolution of Sister Chromatid Cohesion; Intraflagellar transport; RHO GTPases Activate Formins; Post-chaperonin tubulin folding pathway; MHC class II antigen presentation","Pathogenic Escherichia coli infection; Parkin-Ubiquitin Proteasomal System pathway; Exercise-induced Circadian Regulation",66,5,1.234,0.3,0.00521065699593981,0.112478730673498,105,107.7,87.3,"",4.37,3.67,1827.1,"","",1835.5,1914.8,1756.5,1934.3,1571.2,1441.9,1500.8,1538.3,92.7,"","",1464.7,1449.3,1394.8,1400.9,1131.6,1441.9,1223.2,1227.5,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P00568","Adenylate kinase isoenzyme 1 OS=Homo sapiens OX=9606 GN=AK1 PE=1 SV=3",0,54.862,66,13,26,13,194,21.6,8.63,79.71,13,"metabolic process","cytoplasm;cytosol","catalytic activity;nucleotide binding","Pf00406, Pf06414, Pf13207, Pf13238, Pf13671","203","ENSG00000106992.17","AK1","9","Thiamine metabolism; Metabolic pathways; Purine metabolism","Interconversion of nucleotide di- and triphosphates","",6,0,0.83,-0.27,0.00521039914905641,0.112478730673498,92.2,94.3,113.6,"",3.66,4.34,2854,"","",3120.3,2928.4,2883.8,2907.7,3444.2,3419.1,3753.9,3588.3,144.8,"","",2490,2216.5,2290,2105.9,2480.6,3419.1,3059.5,2863.4,"High","High","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P0CG30","Glutathione S-transferase theta-2B OS=Homo sapiens OX=9606 GN=GSTT2B PE=1 SV=1",0,25.288,24,5,6,4,244,27.5,6.4,18.48,5,"metabolic process","cytoplasm;cytosol","catalytic activity;protein binding","Pf00043, Pf02798, Pf13409, Pf13410, Pf13417","2953; 653689","ENSG00000278695.1; ENSG00000133433.10","GSTT2; GSTT2B","22; CHR_HSCHR22_1_CTG7","Chemical carcinogenesis; Glutathione metabolism; Drug metabolism - cytochrome P450; Platinum drug resistance; Metabolism of xenobiotics by cytochrome P450","Glutathione conjugation","Glutathione metabolism; Oxidative Stress; Metapathway biotransformation",12,1,1.244,0.31,0.00525246044575534,0.112481261790733,112.2,104.1,83.7,"",4.04,2.12,1190.5,"","",1124.4,1091.6,1117.9,1027.8,917.3,872,889.2,887.4,60.4,"","",897.3,826.2,887.7,744.4,660.7,872,724.7,708.1,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q16890","Tumor protein D53 OS=Homo sapiens OX=9606 GN=TPD52L1 PE=1 SV=1",0,12.831,7,1,2,1,204,22.4,5.62,8.06,1,"regulation of biological process","cytoplasm","protein binding","Pf04201","7164","ENSG00000111907.20","TPD52L1","6","","Golgi Associated Vesicle Biogenesis","",5,0,0.759,-0.4,0.00524999239667312,0.112481261790733,111.1,81.5,107.4,"",5.68,10.97,228.6,"","",166.8,168.7,171.9,150.9,221.5,225.8,220.7,176.6,11.6,"","",133.1,127.7,136.5,109.3,159.5,225.8,179.9,140.9,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P07711","Cathepsin L1 OS=Homo sapiens OX=9606 GN=CTSL PE=1 SV=2",0,28.746,24,9,12,9,333,37.5,5.45,26.9,9,"cell death;cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus","extracellular;nucleus;organelle lumen;vacuole","catalytic activity;protein binding","Pf00112, Pf08246","1514","ENSG00000135047.14","CTSL; CTSL1","9","Proteoglycans in cancer; Lysosome; Rheumatoid arthritis; Apoptosis; Antigen processing and presentation; Phagosome","Collagen degradation; RUNX1 regulates transcription of genes involved in differentiation of keratinocytes; Assembly of collagen fibrils and other multimeric structures; Endosomal/Vacuolar pathway; MHC class II antigen presentation; Trafficking and processing of endosomal TLR","Primary Focal Segmental Glomerulosclerosis FSGS",26,0,1.22,0.29,5.30792817326531E-3,0.113411931376284,107.3,105.9,86.8,"",2.49,1.6,1565,"","",1539.8,1567.8,1551.4,1480.2,1277.4,1292.4,1247.6,1256.4,79.4,"","",1228.8,1186.7,1232,1072,920,1292.4,1016.8,1002.6,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P28074","Proteasome subunit beta type-5 OS=Homo sapiens OX=9606 GN=PSMB5 PE=1 SV=3",0,127.15,60,16,39,16,263,28.5,6.92,147.45,16,"metabolic process;regulation of biological process;response to stimulus;transport","cytoplasm;cytosol;nucleus;proteasome","catalytic activity;protein binding","Pf00227","5693","ENSG00000100804.18","PSMB5","14","Proteasome","Regulation of RAS by GAPs; CDT1 association with the CDC6:ORC:origin complex; Downstream TCR signaling; UCH proteinases; NIK-->noncanonical NF-kB signaling; Hh mutants that don't undergo autocatalytic processing are degraded by ERAD; SCF-beta-TrCP mediated degradation of Emi1; Cross-presentation of soluble exogenous antigens (endosomes); Separation of Sister Chromatids; Vpu mediated degradation of CD4; Hedgehog ligand biogenesis; Regulation of RUNX2 expression and activity; Ub-specific processing proteases; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; ER-Phagosome pathway; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; ABC-family proteins mediated transport; Regulation of activated PAK-2p34 by proteasome mediated degradation; CDK-mediated phosphorylation and removal of Cdc6; FCERI mediated NF-kB activation; Neddylation; Autodegradation of the E3 ubiquitin ligase COP1; G2/M Checkpoints; Regulation of RUNX3 expression and activity; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Regulation of expression of SLITs and ROBOs; Removal of licensing factors from origins; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; Regulation of PTEN stability and activity; Regulation of DNA replication; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; Vif-mediated degradation of APOBEC3G; Antigen processing: Ubiquitination & Proteasome degradation; GLI3 is processed to GLI3R by the proteasome; SCF(Skp2)-mediated degradation of p27/p21; APC/C:Cdc20 mediated degradation of Securin; Interleukin-1 family signaling; AUF1 (hnRNP D0) binds and destabilizes mRNA; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; The role of GTSE1 in G2/M progression after G2 checkpoint; Regulation of ornithine decarboxylase (ODC); Interleukin-20 family signaling; Hedgehog 'on' state; Ubiquitin-dependent degradation of Cyclin D1; Degradation of DVL; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Degradation of AXIN; Autodegradation of Cdh1 by Cdh1:APC/C; Asymmetric localization of PCP proteins; Orc1 removal from chromatin; M/G1 Transition; Activation of NF-kappaB in B cells; Degradation of beta-catenin by the destruction complex; MAPK6/MAPK4 signaling; Dectin-1 mediated noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosis","Proteasome Degradation",150,0,0.829,-0.27,0.00532227412531627,0.113589958959292,125.5,79.1,95.4,61.28,2.42,3.3,3535.9,8943.5,"",3551.2,3659.5,3535.6,3450.2,4357.9,4221,4333.4,4050.5,179.4,2.5,"",2833.9,2769.9,2807.6,2498.8,3138.7,4221,3531.8,3232.2,"High","High","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q6UXH1","Protein disulfide isomerase CRELD2 OS=Homo sapiens OX=9606 GN=CRELD2 PE=1 SV=1",0,34.213,18,7,8,7,353,38.2,4.59,30.08,7,"","endoplasmic reticulum;extracellular;Golgi","metal ion binding;protein binding","Pf07645, Pf11938","79174","ENSG00000184164.14","CRELD2","22","","","",0,0,1.244,0.32,0.00540224180195148,0.11464892489355,203.1,53.7,43.2,120.58,7.87,3.87,1318.6,"",16579.5,1261.3,1212.2,1315.7,1090.7,996.5,990.8,1020.7,931,66.9,"",2.1,1006.5,917.5,1044.8,789.9,717.7,990.8,831.9,742.9,"High","Not Found","High","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P61587","Rho-related GTP-binding protein RhoE OS=Homo sapiens OX=9606 GN=RND3 PE=1 SV=1",0,9.127,9,2,2,2,244,27.4,8.48,4.84,2,"cell organization and biogenesis;regulation of biological process;response to stimulus","Golgi;membrane","catalytic activity;nucleotide binding;protein binding","Pf00025, Pf00071, Pf08477","390","ENSG00000115963.13","RND3","2","","","",0,0,0.752,-0.41,0.00538644953778644,0.11464892489355,84.8,92.4,122.9,"",10.25,1.07,134,"","",138,135.9,154.6,168.5,191.9,195.5,193.1,196.4,6.8,"","",110.1,102.9,122.8,122,138.2,195.5,157.4,156.7,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q8WWK9-5","Isoform 3 of Cytoskeleton-associated protein 2 OS=Homo sapiens OX=9606 GN=CKAP2",0,51.074,19,13,16,2,682,76.9,9.41,52.11,13,"cell death;regulation of biological process","cytoskeleton;cytosol","","Pf08542, Pf15297","26586","ENSG00000136108.14","CKAP2","13","","","",0,9,0.804,-0.31,0.00544135759855058,0.11522013713164,89,94,116.9,"",5.86,5.54,772.6,"","",787,859.3,846.2,759.4,983.3,1026.8,1112.6,1002.2,39.2,"","",628,650.4,672,550,708.2,1026.8,906.8,799.7,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q8WVD5","RING finger protein 141 OS=Homo sapiens OX=9606 GN=RNF141 PE=1 SV=1",0,6.957,10,2,2,2,230,25.5,5.2,5.6,2,"metabolic process;regulation of biological process","membrane","catalytic activity;DNA binding;metal ion binding;protein binding","Pf00097, Pf12678, Pf13445, Pf13639, Pf13920, Pf13923, Pf14447, Pf14634, Pf15227","50862","ENSG00000110315.6","RNF141","11","","","",0,0,0.733,-0.45,5.43781590930781E-3,0.11522013713164,114.4,78.5,107.1,"",15.81,17.55,76.9,"","",46.7,50.2,55.4,66.6,92.3,71.1,72.8,61.2,3.9,"","",37.3,38,44,48.2,66.5,71.1,59.3,48.8,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","O00220","Tumor necrosis factor receptor superfamily member 10A OS=Homo sapiens OX=9606 GN=TNFRSF10A PE=1 SV=3",0,5.774,5,2,2,2,468,50.1,7.03,3.14,2,"cell death;cellular component movement;defense response;development;metabolic process;regulation of biological process;response to stimulus","cell surface;membrane","protein binding;receptor activity;signal transducer activity","Pf00020, Pf00531","8797","ENSG00000104689.9","TNFRSF10A","8","Influenza A; Apoptosis; Cytokine-cytokine receptor interaction; Measles; Natural killer cell mediated cytotoxicity","Dimerization of procaspase-8; TRAIL  signaling; Cell surface interactions at the vascular wall; TP53 Regulates Transcription of Death Receptors and Ligands; Regulation by c-FLIP; CASP8 activity is inhibited","",26,0,1.305,0.38,0.00547375050055754,0.115776259187604,97.5,114.6,87.9,"",23.87,22.09,205,"","",243.2,238.9,290.4,156.9,203.3,185.2,184.3,116.8,10.4,"","",194.1,180.8,230.6,113.6,146.4,185.2,150.2,93.2,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P33981","Dual specificity protein kinase TTK OS=Homo sapiens OX=9606 GN=TTK PE=1 SV=2",0,89.452,26,20,25,20,857,97,8.16,80.84,20,"cell organization and biogenesis;metabolic process;regulation of biological process","chromosome;cytoplasm;membrane","catalytic activity;nucleotide binding;protein binding","Pf00069, Pf07714, Pf14531","7272","ENSG00000112742.9","TTK","6","Cell cycle","","Retinoblastoma (RB) in Cancer",2,0,0.825,-0.28,0.00554383706088113,0.116996641794327,93.4,93.4,113.2,"",0.71,4.01,1391.5,"","",1397,1392.1,1374.4,1390.6,1694.7,1617.5,1782.2,1678.9,70.6,"","",1114.8,1053.7,1091.4,1007.1,1220.6,1617.5,1452.5,1339.7,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P42898","Methylenetetrahydrofolate reductase OS=Homo sapiens OX=9606 GN=MTHFR PE=1 SV=3",0,27.344,11,6,7,6,656,74.5,5.34,23.41,6,"cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus","cytosol","catalytic activity;nucleotide binding;protein binding","Pf02219","4524","ENSG00000177000.10","MTHFR","1","Carbon metabolism; Metabolic pathways; Antifolate resistance; One carbon pool by folate","Metabolism of folate and pterines","Selenium Micronutrient Network; Vitamin B12 Metabolism; Folate-Alcohol and Cancer Pathway; Fluoropyrimidine Activity; Folate Metabolism; One carbon donor; One Carbon Metabolism; Trans-sulfuration and one carbon metabolism; One carbon metabolism and related pathways",17,0,1.325,0.41,0.00562928827188114,0.118535113577805,"",171,129,"",3.2,11.34,"","","",97.2,96.3,91.8,91.4,86.6,68.5,72.5,69.4,"","","",77.6,72.9,72.9,66.2,62.4,68.5,59.1,55.4,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q2F7J0","Gag-Pol polyprotein OS=Xenotropic MuLV-related virus (isolate VP42) OX=356664 GN=gag-pol PE=3 SV=1",0,18.59,3,4,5,4,1733,193.6,9,14.32,4,"cell organization and biogenesis;metabolic process","membrane","catalytic activity;DNA binding;metal ion binding;RNA binding;structural molecule activity","Pf00075, Pf00077, Pf00078, Pf00665, Pf01140, Pf01141, Pf02093, Pf13650","","","","","","","",0,0,1.27,0.35,0.0057399164757419,0.120328015975375,247.9,29.2,23,137.06,7.8,5.41,544,"",34738,496.4,449.1,527.4,535.6,412.5,378,393.2,427.8,27.6,"",4.4,396.1,339.9,418.8,387.9,297.1,378,320.5,341.4,"High","Not Found","High","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","O15027-5","Isoform 5 of Protein transport protein Sec16A OS=Homo sapiens OX=9606 GN=SEC16A",0,281.626,27,53,69,3,2379,254,5.85,216.65,53,"","","","","","","","","","","",0,45,0.844,-0.24,0.0057482492364147,0.120369103744347,96.7,93.1,110.2,"",2.22,2.05,8315.6,"","",8023.3,8226.6,7985.3,7793.4,9314,9500.8,9781.1,9462.1,421.9,"","",6402.6,6226.7,6341.1,5644.3,6708.2,9500.8,7971.7,7550.5,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q02083","N-acylethanolamine-hydrolyzing acid amidase OS=Homo sapiens OX=9606 GN=NAAA PE=1 SV=3",0,8.114,6,2,2,2,359,40,8.75,6.55,2,"metabolic process;transport","cytoplasm;organelle lumen;vacuole","catalytic activity;protein binding","Pf02275, Pf15508","27163","ENSG00000138744.14","NAAA","4","","Neurotransmitter release cycle","",3,0,1.289,0.37,0.00581363225182185,0.121468900411959,121.6,100.4,77.9,"",11,4.8,534.1,"","",459.8,423.2,465.2,363,344.9,334.9,339.6,372.2,27.1,"","",366.9,320.3,369.4,262.9,248.4,334.9,276.8,297,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P55211","Caspase-9 OS=Homo sapiens OX=9606 GN=CASP9 PE=1 SV=3",0,10.947,12,3,3,3,416,46.3,6.05,5.74,3,"cell death;cell differentiation;metabolic process;regulation of biological process;response to stimulus","cytoplasm;cytosol;mitochondrion;nucleus","catalytic activity;enzyme regulator activity;protein binding","Pf00619, Pf00656","842","ENSG00000132906.17","CASP9","1","Pathways in cancer; Platinum drug resistance; Huntington's disease; Amyotrophic lateral sclerosis (ALS); Parkinson's disease; Thyroid hormone signaling pathway; Endometrial cancer; Legionellosis; Hepatitis B; p53 signaling pathway; Toxoplasmosis; VEGF signaling pathway; Viral myocarditis; Apoptosis - multiple species; Pancreatic cancer; Small cell lung cancer; Prostate cancer; Alzheimer's disease; Colorectal cancer; PI3K-Akt signaling pathway; Apoptosis; Non-small cell lung cancer; Influenza A; Tuberculosis","AKT phosphorylates targets in the cytosol; Ligand-independent caspase activation via DCC; NOD1/2 Signaling Pathway; SMAC-mediated dissociation of IAP:caspase complexes ; SMAC binds to IAPs ; Activation of caspases through apoptosome-mediated cleavage; Formation of apoptosome; Constitutive Signaling by AKT1 E17K in Cancer","Nucleotide-binding Oligomerization Domain (NOD) pathway; miRNA Regulation of DNA Damage Response; Integrated Breast Cancer Pathway; Alzheimers Disease; TNF alpha Signaling Pathway; AGE/RAGE pathway; Allograft Rejection; Corticotropin-releasing hormone signaling pathway; Parkinsons Disease Pathway; Amyotrophic lateral sclerosis (ALS); Nanomaterial induced apoptosis; Apoptosis; Fas Ligand (FasL) pathway and Stress induction of Heat Shock Proteins (HSP) regulation; Rac1/Pak1/p38/MMP-2 pathway; Hepatitis C and Hepatocellular Carcinoma; MAPK Signaling Pathway; Apoptosis Modulation by HSP70; Focal Adhesion-PI3K-Akt-mTOR-signaling pathway; Oxidative Damage; DNA Damage Response",68,0,0.781,-0.36,0.00582781213571915,0.12149637485592,103.5,86.1,110.3,"",4.85,6.29,433.6,"","",368.7,340.2,380.1,352.9,433.3,441.5,483.3,491,22,"","",294.2,257.5,301.8,255.6,312.1,441.5,393.9,391.8,"High","High","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","O95164","Ubiquitin-like protein 3 OS=Homo sapiens OX=9606 GN=UBL3 PE=1 SV=1",0,9.193,23,2,3,2,117,13.1,6.77,9.54,2,"","membrane","protein binding","Pf00240, Pf06838, Pf13881","5412","ENSG00000122042.9","UBL3","13","","","",0,0,1.313,0.39,0.00595766927593955,0.123521907007625,105.7,110.3,84,"",1.67,5.83,153.7,"","",164.5,161.2,159.8,158.2,120.4,111.9,128.6,124.1,7.8,"","",131.3,122,126.9,114.6,86.7,111.9,104.8,99,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P04075","Fructose-bisphosphate aldolase A OS=Homo sapiens OX=9606 GN=ALDOA PE=1 SV=2",0,324.993,82,27,172,1,364,39.4,8.09,529.66,27,"cell organization and biogenesis;cellular homeostasis;metabolic process;regulation of biological process;transport","cytoplasm;cytoskeleton;cytosol;extracellular;membrane;nucleus;organelle lumen","catalytic activity;protein binding;RNA binding","Pf00274","226","ENSG00000149925.17","ALDOA","16","Fructose and mannose metabolism; Metabolic pathways; Pentose phosphate pathway; HIF-1 signaling pathway; Biosynthesis of amino acids; Glycolysis / Gluconeogenesis; Carbon metabolism","Platelet degranulation ; Gluconeogenesis; Glycolysis; Neutrophil degranulation","Glycolysis and Gluconeogenesis; Sudden Infant Death Syndrome (SIDS) Susceptibility Pathways",21,0,0.772,-0.37,0.00607715626626004,0.12581782365417,90.7,91.2,118.1,"",6.46,12.57,236.5,"","",229.2,247.1,224.9,258.1,323.6,317.6,298.9,242.1,12,"","",182.9,187,178.6,186.9,233.1,317.6,243.6,193.2,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q9BV38","WD repeat-containing protein 18 OS=Homo sapiens OX=9606 GN=WDR18 PE=1 SV=2",0,39.64,19,11,17,11,432,47.4,6.7,47.5,11,"development;metabolic process","cytoplasm;nucleus","protein binding","Pf00400, Pf14077","57418","ENSG00000065268.10","WDR18","19","","Major pathway of rRNA processing in the nucleolus and cytosol","",4,0,0.826,-0.28,0.00608811074427029,0.12581782365417,92.2,94,113.8,"",3.12,1.96,1720.7,"","",1739.1,1769.1,1785.4,1662.8,2192.2,2135.4,2097.6,2111.3,87.3,"","",1387.8,1339,1417.8,1204.3,1578.9,2135.4,1709.6,1684.8,"High","High","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P78540","Arginase-2, mitochondrial OS=Homo sapiens OX=9606 GN=ARG2 PE=1 SV=1",0,15.971,15,4,4,4,354,38.6,6.47,12.16,4,"defense response;metabolic process;regulation of biological process;response to stimulus","mitochondrion;organelle lumen","catalytic activity;metal ion binding","Pf00491","384","ENSG00000081181.7","ARG2","14","Metabolic pathways; Arginine biosynthesis; Biosynthesis of amino acids; Arginine and proline metabolism; Amoebiasis","Urea cycle","Amino Acid metabolism; Urea cycle and metabolism of amino groups",11,0,0.697,-0.52,0.00608838896759378,0.12581782365417,"",123.3,176.7,"",16.64,14.58,"","","",36.6,48.9,34.1,37.7,40,53,53.5,56.8,"","","",29.2,37,27.1,27.3,28.8,53,43.6,45.3,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q96DX5","Ankyrin repeat and SOCS box protein 9 OS=Homo sapiens OX=9606 GN=ASB9 PE=1 SV=1",0,34.395,24,6,9,6,294,31.8,6.98,33.42,6,"metabolic process;regulation of biological process;response to stimulus","cytosol;mitochondrion","protein binding","Pf00023, Pf07525, Pf12796, Pf13606, Pf13637, Pf13857","140462","ENSG00000102048.15","ASB9","X","","Antigen processing: Ubiquitination & Proteasome degradation; Neddylation","",7,0,0.778,-0.36,0.00616396074984538,0.126962803318516,87.6,93,119.5,"",6.24,5.28,295.6,"","",304.6,322.5,305.5,347.3,414.2,414.5,393,370.3,15,"","",243.1,244.1,242.6,251.5,298.3,414.5,320.3,295.5,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","O95785-3","Isoform 3 of Protein Wiz OS=Homo sapiens OX=9606 GN=WIZ",0,95.544,27,19,23,1,965,102.9,9.52,61.68,19,"cell organization and biogenesis;regulation of biological process","nucleus","metal ion binding;protein binding","","58525","ENSG00000011451.17","WIZ","19","","","",0,14,0.821,-0.29,0.00624953619617363,0.128027374916841,98.7,90.7,110.6,"",3.78,1.89,1996.6,"","",1834.7,1834.9,1896.6,1730.5,2191.1,2238.8,2233.3,2294.2,101.3,"","",1464.1,1388.8,1506.1,1253.3,1578.1,2238.8,1820.2,1830.7,"Not Found","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","O00560","Syntenin-1 OS=Homo sapiens OX=9606 GN=SDCBP PE=1 SV=1",0,38.681,35,6,9,6,298,32.4,7.53,30.16,6,"cell communication;cell organization and biogenesis;regulation of biological process;response to stimulus;transport","cytoplasm;cytoskeleton;cytosol;endoplasmic reticulum;extracellular;membrane;nucleus;organelle lumen","protein binding","Pf00595, Pf13180","6386","ENSG00000137575.11","SDCBP","8","","Ephrin signaling; Neutrophil degranulation; Neurofascin interactions","Ectoderm Differentiation",10,0,0.82,-0.29,0.00624193111363325,0.128027374916841,82.1,98.2,119.7,"",20.87,23.02,839.6,"","",962.8,1046.4,795.1,1309.8,1785.3,1249.5,1102.6,1197.8,42.6,"","",768.3,792,631.4,948.6,1285.8,1249.5,898.6,955.8,"High","Not Found","High","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P14635","G2/mitotic-specific cyclin-B1 OS=Homo sapiens OX=9606 GN=CCNB1 PE=1 SV=1",0,30.197,15,6,9,6,433,48.3,7.47,28.3,6,"cell division;cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus","cytoplasm;cytoskeleton;cytosol;membrane;nucleus;organelle lumen","catalytic activity;enzyme regulator activity;protein binding","Pf00134, Pf02984","891","ENSG00000134057.14","CCNB1","5","Cell cycle; p53 signaling pathway; FoxO signaling pathway; Oocyte meiosis; Progesterone-mediated oocyte maturation","APC/C:Cdc20 mediated degradation of Cyclin B; Condensation of Prometaphase Chromosomes; G2/M DNA replication checkpoint; Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex; Regulation of PLK1 Activity at G2/M Transition; Polo-like kinase mediated events; Phosphorylation of Emi1; TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest; E2F-enabled inhibition of pre-replication complex formation; Phosphorylation of the APC/C; Cyclin A/B1/B2 associated events during G2/M transition; Depolymerisation of the Nuclear Lamina; Resolution of Sister Chromatid Cohesion; Condensation of Prophase Chromosomes; MASTL Facilitates Mitotic Progression; Activation of NIMA Kinases NEK9, NEK6, NEK7; Golgi Cisternae Pericentriolar Stack Reorganization; Nuclear Pore Complex (NPC) Disassembly; The role of GTSE1 in G2/M progression after G2 checkpoint; Transcriptional regulation by RUNX2","AMP-activated Protein Kinase (AMPK) Signaling; miRNA Regulation of DNA Damage Response; Cell Cycle; Retinoblastoma (RB) in Cancer; ATM Signaling Pathway; G1 to S cell cycle control; DNA Damage Response",56,0,0.831,-0.27,0.00624515454943997,0.128027374916841,94.4,93.3,112.3,"",0.79,3.63,1484.2,"","",1466.4,1443.5,1466.2,1467.2,1806.4,1665.7,1791.3,1739.3,75.3,"","",1170.2,1092.6,1164.3,1062.6,1301,1665.7,1459.9,1387.9,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q9H568","Actin-like protein 8 OS=Homo sapiens OX=9606 GN=ACTL8 PE=1 SV=1",0,68.435,40,13,16,13,366,41.3,6.14,57.13,13,"cell differentiation","cytoplasm;cytoskeleton","protein binding","Pf00022","81569","ENSG00000117148.7","ACTL8","1","","","",0,0,1.204,0.27,0.00628864519280947,0.128688982017102,107.2,105.4,87.5,"",11.34,4.99,1663.5,"","",1674.3,1597.7,1894.7,1444.7,1410.5,1341,1375.3,1254,84.4,"","",1336.1,1209.3,1504.6,1046.3,1015.9,1341,1120.9,1000.7,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P19957","Elafin OS=Homo sapiens OX=9606 GN=PI3 PE=1 SV=3",1E-3,4.971,14,1,1,1,117,12.3,8.82,2.81,1,"cell death;metabolic process;regulation of biological process;response to stimulus","cytoskeleton;cytosol;extracellular","enzyme regulator activity;structural molecule activity","Pf00095, Pf10511","5266","ENSG00000124102.4","PI3","20","","Antimicrobial peptides; Formation of the cornified envelope","",6,0,1.309,0.39,0.00630834602358421,0.128952423910669,75.9,127,97,"",5.59,14.47,55.2,"","",95.7,84.2,93.9,90.7,63.5,78.4,60.9,81.1,2.8,"","",76.4,63.7,74.6,65.7,45.7,78.4,49.6,64.7,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q96HE7","ERO1-like protein alpha OS=Homo sapiens OX=9606 GN=ERO1A PE=1 SV=2",0,87.853,28,13,27,12,468,54.4,5.68,89.15,13,"cell death;cell differentiation;cell organization and biogenesis;cellular homeostasis;metabolic process;regulation of biological process;response to stimulus;transport","endoplasmic reticulum;membrane;organelle lumen","catalytic activity;protein binding","Pf04137","30001","ENSG00000197930.12","ERO1L; ERO1A","14","Vibrio cholerae infection; Protein processing in endoplasmic reticulum","Insulin processing; Detoxification of Reactive Oxygen Species","",8,2,1.196,0.26,6.34364281546973E-3,0.129533757295775,101.9,107.9,90.2,"",5.17,2.06,3884.8,"","",4154.7,4066.1,4226.2,3751.1,3450.7,3530.7,3359.1,3423.8,197.1,"","",3315.5,3077.6,3356,2716.7,2485.3,3530.7,2737.7,2732.1,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q13085","Acetyl-CoA carboxylase 1 OS=Homo sapiens OX=9606 GN=ACACA PE=1 SV=2",0,285.817,32,64,78,57,2346,265.4,6.37,240.65,64,"cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus;transport","cytoplasm;cytoskeleton;cytosol;mitochondrion","catalytic activity;metal ion binding;nucleotide binding;protein binding","Pf00289, Pf00364, Pf01039, Pf02222, Pf02655, Pf02785, Pf02786, Pf07478, Pf08326, Pf13535, Pf15632","31","ENSG00000278540.4; ENSG00000275176.4","ACACA","17; CHR_HSCHR17_7_CTG4","Fatty acid biosynthesis; Propanoate metabolism; AMPK signaling pathway; Pyruvate metabolism; Metabolic pathways; Fatty acid metabolism; Glucagon signaling pathway; Insulin signaling pathway","Fatty acyl-CoA biosynthesis; Import of palmitoyl-CoA into the mitochondrial matrix; Activation of gene expression by SREBF (SREBP); Defective HLCS causes multiple carboxylase deficiency; ChREBP activates metabolic gene expression; Biotin transport and metabolism","AMP-activated Protein Kinase (AMPK) Signaling; Sterol Regulatory Element-Binding Proteins (SREBP) signalling; Leptin signaling pathway; Corticotropin-releasing hormone signaling pathway; Mesodermal Commitment Pathway; Fatty Acid Biosynthesis; VEGFA-VEGFR2 Signaling Pathway; Focal Adhesion-PI3K-Akt-mTOR-signaling pathway; Leptin and adiponectin",35,7,1.181,0.24,0.00641011277417158,0.130327459718571,114.1,100.7,85.2,22.02,3.32,1.8,10192,13951.9,"",10592.2,10456.2,10670.9,9904.4,8920.5,8855.7,9208.3,8895.5,517.1,3.9,"",8452.6,7914.3,8473.7,7173.2,6424.8,8855.7,7504.9,7098.4,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,"Acetyl [N-Term]"]
[false,"High","Master Protein","Q9BVM2","Protein DPCD OS=Homo sapiens OX=9606 GN=DPCD PE=1 SV=2",0,33.624,33,9,14,9,203,23.2,9.03,31.15,9,"cellular component movement","nucleus","protein binding","Pf14913","25911","ENSG00000166171.12","DPCD","10","","","",0,0,1.235,0.3,0.00643205833546401,0.130633029935746,197.1,56.8,46,117.35,2.34,3.21,2570.2,"",27632.5,2465,2413.7,2446.1,2336.7,1894.5,1944.9,1991.1,2042.3,130.4,"",3.5,1967.1,1826.9,1942.4,1692.3,1364.5,1944.9,1622.8,1629.7,"High","Not Found","High","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q14249","Endonuclease G, mitochondrial OS=Homo sapiens OX=9606 GN=ENDOG PE=1 SV=4",0,18.85,26,6,6,6,297,32.6,9.5,13.84,6,"cell death;cellular homeostasis;metabolic process;regulation of biological process;response to stimulus","cytosol;mitochondrion;nucleus","catalytic activity;metal ion binding;protein binding","Pf01223","2021","ENSG00000167136.6","ENDOG","9","Apoptosis","","Nanomaterial induced apoptosis",2,0,0.762,-0.39,6.4715786166718E-3,0.131294497219868,100.2,86.4,113.4,"",3.93,5.21,187.2,"","",160.4,159.7,162.6,173.6,218.8,223.6,200.1,205.4,9.5,"","",128,120.9,129.1,125.7,157.6,223.6,163.1,163.9,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q99956","Dual specificity protein phosphatase 9 OS=Homo sapiens OX=9606 GN=DUSP9 PE=1 SV=1",0,19.512,18,4,4,4,384,41.8,6.11,16.26,4,"metabolic process;regulation of biological process;response to stimulus","cytoplasm;cytosol;nucleus","catalytic activity;protein binding","Pf00102, Pf00782, Pf03162, Pf14566","1852","ENSG00000130829.17","DUSP9","X","MAPK signaling pathway; Signaling pathways regulating pluripotency of stem cells","Negative regulation of MAPK pathway; RAF-independent MAPK1/3 activation; Interleukin-20 family signaling","",12,0,0.797,-0.33,6.50233638694875E-3,0.131776963172412,84.6,95.5,119.8,"",6.75,2.78,402.1,"","",440.7,467,426.4,496.5,582.3,560.7,548.2,578,20.4,"","",351.7,353.5,338.6,359.6,419.4,560.7,446.8,461.2,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P25787","Proteasome subunit alpha type-2 OS=Homo sapiens OX=9606 GN=PSMA2 PE=1 SV=2",0,72.626,41,8,28,8,234,25.9,7.43,97.27,8,"metabolic process;regulation of biological process;response to stimulus;transport","cytoplasm;cytosol;extracellular;nucleus;organelle lumen;proteasome","catalytic activity;protein binding","Pf00227, Pf10584","5683","ENSG00000256646.7; ENSG00000106588.10","PSMA2","7","Proteasome","Regulation of RAS by GAPs; CDT1 association with the CDC6:ORC:origin complex; Downstream TCR signaling; UCH proteinases; NIK-->noncanonical NF-kB signaling; Hh mutants that don't undergo autocatalytic processing are degraded by ERAD; SCF-beta-TrCP mediated degradation of Emi1; Neutrophil degranulation; Cross-presentation of soluble exogenous antigens (endosomes); Separation of Sister Chromatids; Vpu mediated degradation of CD4; Hedgehog ligand biogenesis; Regulation of RUNX2 expression and activity; Ub-specific processing proteases; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; ER-Phagosome pathway; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; ABC-family proteins mediated transport; Regulation of activated PAK-2p34 by proteasome mediated degradation; CDK-mediated phosphorylation and removal of Cdc6; FCERI mediated NF-kB activation; Neddylation; Autodegradation of the E3 ubiquitin ligase COP1; G2/M Checkpoints; Regulation of RUNX3 expression and activity; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Regulation of expression of SLITs and ROBOs; Removal of licensing factors from origins; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; Regulation of PTEN stability and activity; Regulation of DNA replication; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; Vif-mediated degradation of APOBEC3G; Antigen processing: Ubiquitination & Proteasome degradation; GLI3 is processed to GLI3R by the proteasome; SCF(Skp2)-mediated degradation of p27/p21; APC/C:Cdc20 mediated degradation of Securin; Interleukin-1 family signaling; AUF1 (hnRNP D0) binds and destabilizes mRNA; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; The role of GTSE1 in G2/M progression after G2 checkpoint; Regulation of ornithine decarboxylase (ODC); Interleukin-20 family signaling; Hedgehog 'on' state; Ubiquitin-dependent degradation of Cyclin D1; Degradation of DVL; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Degradation of AXIN; Autodegradation of Cdh1 by Cdh1:APC/C; Asymmetric localization of PCP proteins; Orc1 removal from chromatin; M/G1 Transition; Activation of NF-kappaB in B cells; Degradation of beta-catenin by the destruction complex; MAPK6/MAPK4 signaling; Dectin-1 mediated noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosis","Proteasome Degradation",151,0,0.827,-0.27,6.59364519332195E-3,0.132824196247098,96.6,92.1,111.3,"",1.5,4.23,4020.8,"","",3925.7,3834.7,3790.6,3825.2,4794,4648.1,4613.2,4329.1,204,"","",3132.7,2902.5,3010.1,2770.4,3452.8,4648.1,3759.8,3454.5,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q6P587","Acylpyruvase FAHD1, mitochondrial OS=Homo sapiens OX=9606 GN=FAHD1 PE=1 SV=2",0,23.601,32,7,7,7,224,24.8,7.39,18.25,7,"metabolic process","cytoplasm;cytosol;membrane;mitochondrion","catalytic activity;metal ion binding","Pf01557","81889","ENSG00000180185.11","FAHD1","16","Tyrosine metabolism; Metabolic pathways","","",2,0,1.227,0.3,0.00660050351852948,0.132824196247098,102.7,108.7,88.6,"",9.37,2.73,1852.7,"","",1925.7,1999.9,2007.1,1631.1,1572,1565,1627,1655.7,94,"","",1536.7,1513.7,1593.8,1181.3,1132.2,1565,1326,1321.2,"High","High","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","O15554","Intermediate conductance calcium-activated potassium channel protein 4 OS=Homo sapiens OX=9606 GN=KCNN4 PE=1 SV=1",0,10.879,5,2,2,2,427,47.7,9.83,5.91,2,"cell organization and biogenesis;cellular homeostasis;defense response;regulation of biological process;response to stimulus;transport","membrane","protein binding;transporter activity","Pf02888, Pf03530, Pf07885","3783","ENSG00000104783.11","KCNN4","19","Salivary secretion; Protein digestion and absorption; Insulin secretion","Ca2+ activated K+ channels","",6,0,0.764,-0.39,0.00661830677899955,0.132824196247098,71.9,98.8,129.3,"",7.89,6.66,149.8,"","",185.7,206.6,225.4,204.6,246.3,265.4,273.1,289.4,7.6,"","",148.2,156.4,179,148.2,177.4,265.4,222.6,230.9,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q9H967","WD repeat-containing protein 76 OS=Homo sapiens OX=9606 GN=WDR76 PE=1 SV=2",0,39.514,16,10,13,10,626,69.7,9.25,39,10,"regulation of biological process;response to stimulus","nucleus","DNA binding;protein binding","Pf00400","79968","ENSG00000092470.11","WDR76","15","","","",0,0,0.83,-0.27,0.00664918356235877,0.133181101936196,93.6,93.6,112.8,"",11.67,8.67,1444.7,"","",1494.2,1395.4,1529.3,1167.4,1518.4,1660.2,1827.3,1823,73.3,"","",1192.4,1056.2,1214.4,845.5,1093.6,1660.2,1489.3,1454.7,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","O14965","Aurora kinase A OS=Homo sapiens OX=9606 GN=AURKA PE=1 SV=2",0,69.681,39,12,15,12,403,45.8,9.39,58.15,12,"cell division;cell growth;cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus","cytoplasm;cytoskeleton;cytosol;nucleus","catalytic activity;nucleotide binding;protein binding","Pf00069, Pf01636, Pf07714, Pf14531","6790","","AURKA","20","Oocyte meiosis","FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; Interaction between PHLDA1 and AURKA; Regulation of PLK1 Activity at G2/M Transition; AURKA Activation by TPX2; TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest; SUMOylation of DNA replication proteins; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Regulation of TP53 Activity through Phosphorylation","Gastric Cancer Network 1; EGF/EGFR Signaling Pathway",27,0,0.822,-0.28,0.0067078762762085,0.13421437193329,77.9,100.2,121.9,"",12.41,13.13,833.7,"","",1075.4,1070,1085.1,825.6,1126.7,1269.8,1543.3,1340.6,42.3,"","",858.2,809.9,861.7,597.9,811.5,1269.8,1257.8,1069.8,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q05639","Elongation factor 1-alpha 2 OS=Homo sapiens OX=9606 GN=EEF1A2 PE=1 SV=1",0,139.759,50,22,114,9,463,50.4,9.03,305.25,22,"metabolic process;regulation of biological process;response to stimulus","cytoplasm;nucleus","catalytic activity;nucleotide binding;protein binding;RNA binding","Pf00009, Pf03143, Pf03144","1917","ENSG00000101210.10","EEF1A2","20","RNA transport; Legionellosis","Eukaryotic Translation Elongation","Translation Factors",6,0,1.208,0.27,0.00673534186285552,0.134621309106471,196.7,56.5,46.8,119.79,4.5,1.05,3072.8,"",37106.5,3103,3057.2,3075.7,2810.3,2509.8,2567.2,2554.3,2522.9,155.9,"",4.7,2476.2,2314,2442.4,2035.3,1807.6,2567.2,2081.8,2013.2,"High","Not Found","High","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P15104","Glutamine synthetase OS=Homo sapiens OX=9606 GN=GLUL PE=1 SV=4",0,5.671,6,2,2,2,373,42,6.89,6.64,2,"cell communication;cell organization and biogenesis;cell proliferation;metabolic process;regulation of biological process;response to stimulus;transport","cytoplasm;cytosol;endoplasmic reticulum;mitochondrion;nucleus","catalytic activity;metal ion binding;nucleotide binding;protein binding","Pf00120, Pf03951","2752","ENSG00000135821.17","GLUL","1","GABAergic synapse; Glutamatergic synapse; Metabolic pathways; Biosynthesis of amino acids; Arginine biosynthesis; Nitrogen metabolism; Alanine, aspartate and glutamate metabolism; Glyoxylate and dicarboxylate metabolism","Amino acid synthesis and interconversion (transamination); Astrocytic Glutamate-Glutamine Uptake And Metabolism","TNF alpha Signaling Pathway; Amino Acid metabolism",17,0,1.296,0.37,0.00678306504392268,0.135431852589441,82.6,122.7,94.7,"",3.97,7.6,153.7,"","",226.8,230,219.6,241.5,201.3,174.4,178.2,170.8,7.8,"","",181,174.1,174.4,174.9,145,174.4,145.2,136.3,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q9NVI1","Fanconi anemia group I protein OS=Homo sapiens OX=9606 GN=FANCI PE=1 SV=4",0,118.192,23,26,33,26,1328,149.2,6.74,103.07,26,"metabolic process;regulation of biological process;response to stimulus","cytosol;membrane;nucleus","DNA binding;protein binding","Pf14674, Pf14675, Pf14676, Pf14677, Pf14678, Pf14679, Pf14680","55215","ENSG00000140525.17","FANCI","15","Fanconi anemia pathway","Fanconi Anemia Pathway; TP53 Regulates Transcription of DNA Repair Genes","Gastric cancer network 2",9,0,0.84,-0.25,0.00684779321824425,0.136579850376132,102.1,90.3,107.5,"",9.05,5.53,3632.5,"","",3239.1,3186.9,3159.9,3797.1,3770.3,3533.9,3878.6,4034.7,184.3,"","",2584.8,2412.2,2509.3,2750,2715.5,3533.9,3161.1,3219.6,"High","High","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P01100","Proto-oncogene c-Fos OS=Homo sapiens OX=9606 GN=FOS PE=1 SV=1",1E-3,5.253,11,2,2,2,380,40.7,4.87,6.86,2,"cell communication;cell differentiation;defense response;metabolic process;regulation of biological process;response to stimulus","cytoplasm;cytosol;endoplasmic reticulum;membrane;nucleus","DNA binding;protein binding","Pf00170, Pf07716","2353","ENSG00000170345.9","FOS","14","Leishmaniasis; Salmonella infection; Prolactin signaling pathway; HTLV-I infection; Rheumatoid arthritis; TNF signaling pathway; Colorectal cancer; cAMP signaling pathway; Chagas disease (American trypanosomiasis); Oxytocin signaling pathway; Toll-like receptor signaling pathway; B cell receptor signaling pathway; Apoptosis; Hepatitis B; Pathways in cancer; Cholinergic synapse; T cell receptor signaling pathway; Circadian entrainment; Endocrine resistance; Dopaminergic synapse; Estrogen signaling pathway; Herpes simplex infection; Choline metabolism in cancer; Pertussis; Breast cancer; MAPK signaling pathway; Amphetamine addiction; Osteoclast differentiation; Th1 and Th2 cell differentiation","FCERI mediated MAPK activation; Activated TLR4 signalling; TP53 Regulates Transcription of DNA Repair Genes; Activation of the AP-1 family of transcription factors; Interleukin-4 and 13 signaling; Senescence-Associated Secretory Phenotype (SASP); Oxidative Stress Induced Senescence","IL-5 Signaling Pathway; Regulation of toll-like receptor signaling pathway; Physiological and Pathological Hypertrophy  of the Heart; RANKL/RANK (Receptor activator of NFKB (ligand)) Signaling Pathway; Human Thyroid Stimulating Hormone (TSH) signaling pathway; Prolactin Signaling Pathway; Corticotropin-releasing hormone signaling pathway; Oncostatin M Signaling Pathway; Brain-Derived Neurotrophic Factor (BDNF) signaling pathway; Spinal Cord Injury; Quercetin and Nf-kB/ AP-1 Induced Cell Apoptosis; Structural Pathway of Interleukin 1 (IL-1); Selenium Metabolism and Selenoproteins; IL-3 Signaling Pathway; Myometrial Relaxation and Contraction Pathways; Kit receptor signaling pathway; Signaling of Hepatocyte Growth Factor Receptor; Photodynamic therapy-induced NFE2L2 (NRF2) survival signaling; TGF-beta Signaling Pathway; MAPK Signaling Pathway; T-Cell antigen Receptor (TCR) pathway during Staphylococcus aureus infection; ESC Pluripotency Pathways; Serotonin and anxiety-related events; Serotonin and anxiety; IL-4 Signaling Pathway; Oxidative Stress; EGF/EGFR Signaling Pathway; Insulin Signaling; IL-2 Signaling Pathway; TGF-beta Receptor Signaling; T-Cell antigen Receptor (TCR)  Signaling Pathway; Estrogen signaling pathway; Toll-like receptor signaling pathway",100,0,0.703,-0.51,6.99935549812536E-3,0.139015590587373,"",123.8,176.2,"",15.62,13.22,"","","",27.3,23.9,30.7,34.5,38.6,44,35.5,47.7,"","","",21.8,18.1,24.4,25,27.8,44,28.9,38.1,"Not Found","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q8NFJ5","Retinoic acid-induced protein 3 OS=Homo sapiens OX=9606 GN=GPRC5A PE=1 SV=2",0,20.427,20,5,8,5,357,40.2,8.15,19.39,5,"regulation of biological process;response to stimulus","membrane","protein binding;receptor activity;signal transducer activity","Pf00003","9052","ENSG00000013588.7","GPRC5A","12","","","GPCRs, Class C Metabotropic glutamate, pheromone",1,0,0.831,-0.27,0.00700861967877175,0.139053370265379,101.3,90.2,108.5,"",25.68,12.65,1604.4,"","",1360.9,1499.9,1284.2,2172.9,1733.6,1705.8,1669.8,2160,81.4,"","",1086,1135.3,1019.8,1573.7,1248.6,1705.8,1360.9,1723.6,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q9NYP3","Protein downstream neighbor of Son OS=Homo sapiens OX=9606 GN=DONSON PE=1 SV=2",0,11.095,6,2,2,2,566,62.7,8.66,8.56,2,"development;metabolic process;regulation of biological process;response to stimulus","nucleus","protein binding","","29980","ENSG00000159147.17","DONSON","21","","","",0,0,0.741,-0.43,0.00714830500868313,0.141231365066953,78.9,94.1,127,"",5.14,5.21,65,"","",75.6,79.7,72.8,81.6,96.9,109,102.3,107.1,3.3,"","",60.3,60.3,57.8,59.1,69.8,109,83.4,85.5,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q92805","Golgin subfamily A member 1 OS=Homo sapiens OX=9606 GN=GOLGA1 PE=1 SV=3",0,81.053,28,20,21,20,767,88.1,5.27,71.52,20,"metabolic process;transport","cytosol;Golgi;membrane","catalytic activity;motor activity;protein binding;transporter activity","Pf01465, Pf01496, Pf01576, Pf04111, Pf04156, Pf04849, Pf07888, Pf08317, Pf10212, Pf12128, Pf13166","2800","ENSG00000136935.13","GOLGA1","9","","Retrograde transport at the Trans-Golgi-Network","",4,0,0.829,-0.27,0.00719168445536766,0.141939954015658,96,92.5,111.5,"",2.97,5.44,1878.3,"","",1845.1,1801.7,1818.2,1721.1,2212.2,2252.4,2153.8,1986.4,95.3,"","",1472.4,1363.7,1443.8,1246.5,1593.3,2252.4,1755.4,1585.1,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P49257","Protein ERGIC-53 OS=Homo sapiens OX=9606 GN=LMAN1 PE=1 SV=2",0,134.332,34,15,32,15,510,57.5,6.77,114.9,15,"cell organization and biogenesis;coagulation;metabolic process;regulation of biological process;transport","endoplasmic reticulum;Golgi;membrane","metal ion binding;protein binding","Pf03388","3998","ENSG00000074695.5","LMAN1","18","Protein processing in endoplasmic reticulum","Cargo concentration in the ER; COPII (Coat Protein 2) Mediated Vesicle Transport","Complement and Coagulation Cascades",11,0,1.203,0.27,0.00726411586642173,0.143181525913164,108.5,104.5,86.9,"",4.46,1.16,3547.8,"","",3455.7,3380,3350.4,3692.1,2841.2,2782.1,2842.7,2856.1,180,"","",2757.7,2558.3,2660.5,2674,2046.3,2782.1,2316.8,2279.1,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"Medium","Master Protein","Q96BS2","Calcineurin B homologous protein 3 OS=Homo sapiens OX=9606 GN=TESC PE=1 SV=3",0.011,2.366,5,1,1,1,214,24.7,4.93,2.12,1,"cell differentiation;cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus;transport","cytoplasm;cytosol;membrane;nucleus","enzyme regulator activity;metal ion binding;protein binding","Pf13405","54997","ENSG00000088992.17","TESC","12","","","",0,0,1.303,0.38,0.00727733295619637,0.143181525913164,125,99,76,"",6.49,8.53,169.5,"","",130.6,123.7,143.6,138.1,108.3,107.2,99,89.7,8.6,"","",104.2,93.6,114,100,78,107.2,80.7,71.6,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P55017-2","Isoform 2 of Solute carrier family 12 member 3 OS=Homo sapiens OX=9606 GN=SLC12A3",0,41.687,10,9,10,9,1030,113.9,7.97,32.65,9,"transport","cytosol;membrane","protein binding;transporter activity","Pf00324, Pf08403, Pf13520","6559","ENSG00000070915.9","SLC12A3","16","","","",0,0,0.812,-0.3,7.32898248020852E-3,0.143302092221717,84.1,96.8,119.2,"",8.18,2.44,825.8,"","",930.8,1103.4,943.1,958.5,1172.8,1214.1,1168.2,1145.1,41.9,"","",742.8,835.2,748.9,694.2,844.7,1214.1,952.1,913.8,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q8TEM1","Nuclear pore membrane glycoprotein 210 OS=Homo sapiens OX=9606 GN=NUP210 PE=1 SV=3",0,146.865,20,27,40,27,1887,205,6.81,128.3,27,"cell organization and biogenesis;metabolic process;regulation of biological process;transport","endoplasmic reticulum;membrane;nucleus","protein binding","Pf02368","23225","ENSG00000132182.11","NUP210","3","RNA transport","Rev-mediated nuclear export of HIV RNA; ISG15 antiviral mechanism; NEP/NS2 Interacts with the Cellular Export Machinery; tRNA processing in the nucleus; Transcriptional regulation by small RNAs; Nuclear Pore Complex (NPC) Disassembly; Regulation of Glucokinase by Glucokinase Regulatory Protein; Vpr-mediated nuclear import of PICs; Regulation of HSF1-mediated heat shock response; snRNP Assembly; SUMOylation of DNA replication proteins; Transport of the SLBP independent Mature mRNA; SUMOylation of RNA binding proteins; Viral Messenger RNA Synthesis; SUMOylation of chromatin organization proteins; Nuclear import of Rev protein;  NS1 Mediated Effects on Host Pathways; Transport of Mature mRNA Derived from an Intronless Transcript; Transport of the SLBP Dependant Mature mRNA; Transport of Ribonucleoproteins into the Host Nucleus; Transport of Mature mRNA derived from an Intron-Containing Transcript; SUMOylation of DNA damage response and repair proteins","",64,0,1.187,0.25,0.00736447116302763,0.143542469960469,156.6,77.8,65.5,81.71,3.37,2.73,6319,23610.9,"",6061.9,6074.2,6315.9,5815.2,5148.9,5164,4863.5,5071.3,320.6,6.6,"",4837.4,4597.6,5015.4,4211.6,3708.4,5164,3963.8,4046.8,"High","High","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q5VT66","Mitochondrial amidoxime-reducing component 1 OS=Homo sapiens OX=9606 GN=MARC1 PE=1 SV=1",0,40.403,22,8,12,7,337,37.5,8.88,34.86,8,"metabolic process;response to stimulus","membrane;mitochondrion","catalytic activity;metal ion binding","Pf03473, Pf03476","64757","ENSG00000186205.12","MARC1","1","","Phase I - Functionalization of compounds","",3,0,0.835,-0.26,0.00737167491855439,0.143542469960469,97.8,92,110.2,"",2.63,0.96,1754.2,"","",1614.7,1669.4,1711.4,1629.3,1971.3,1980.5,2003,1958,89,"","",1288.5,1263.6,1359,1180,1419.8,1980.5,1632.5,1562.4,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q9HBL7","Plasminogen receptor (KT) OS=Homo sapiens OX=9606 GN=PLGRKT PE=1 SV=1",0,13.593,25,5,5,5,147,17.2,9.58,14.12,5,"defense response;regulation of biological process;response to stimulus","membrane;mitochondrion","protein binding","Pf10166","55848","ENSG00000107020.9","PLGRKT","9","","","",0,0,1.289,0.37,0.0074991398733748,0.14557425891912,81.7,122.9,95.4,"",12.18,5.23,153.7,"","",238.1,224.9,251.6,187.8,192.9,173.3,185.4,173.8,7.8,"","",190,170.2,199.8,136,138.9,173.3,151.1,138.7,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","O15061","Synemin OS=Homo sapiens OX=9606 GN=SYNM PE=1 SV=2",0,133.521,18,29,32,29,1565,172.7,5.16,105.14,29,"cell organization and biogenesis","cytoplasm;cytoskeleton;membrane","protein binding;structural molecule activity","Pf00038","23336","","SYNM","15","","","",0,0,0.834,-0.26,0.00754561345359761,0.146216916302241,89.3,95.8,114.9,"",4.52,4.32,1279.2,"","",1378.9,1366.1,1388.7,1257.5,1651.3,1641.6,1679.5,1520.8,64.9,"","",1100.4,1034,1102.8,910.7,1189.3,1641.6,1368.8,1213.6,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P05549","Transcription factor AP-2-alpha OS=Homo sapiens OX=9606 GN=TFAP2A PE=1 SV=1",0,36.132,24,11,12,7,437,48,8.02,30.09,11,"metabolic process;regulation of biological process;response to stimulus","cytosol;Golgi;nucleus","DNA binding;protein binding","Pf03299","7020","ENSG00000137203.10","TFAP2A","6","","TFAP2 (AP-2) family regulates transcription of cell cycle factors; Negative regulation of activity of TFAP2 (AP-2) family transcription factors; TFAP2 (AP-2) family regulates transcription of growth factors and their receptors; Activation of the TFAP2 (AP-2) family of transcription factors; TFAP2 (AP-2) family regulates transcription of other transcription factors; TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation; SUMOylation of transcription factors","Neural Crest Differentiation; Corticotropin-releasing hormone signaling pathway; Ectoderm Differentiation; Hypothetical Craniofacial Development Pathway",19,4,0.827,-0.27,0.00758643466625353,0.146216916302241,183.2,52.8,63.9,117.07,1.58,3.51,2022.2,21464.5,"",1883.7,1868.5,1916,1934.4,2298.2,2298.1,2170.4,2361.4,102.6,6,"",1503.2,1414.3,1521.5,1401,1655.2,2298.1,1768.9,1884.3,"High","High","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P19525","Interferon-induced, double-stranded RNA-activated protein kinase OS=Homo sapiens OX=9606 GN=EIF2AK2 PE=1 SV=2",0,74.288,27,16,23,16,551,62.1,8.4,58.04,16,"cell communication;defense response;metabolic process;regulation of biological process;response to stimulus","cytoplasm;cytosol;membrane;nucleus;ribosome","catalytic activity;enzyme regulator activity;nucleotide binding;protein binding;RNA binding","Pf00035, Pf00069, Pf07714","5610","ENSG00000055332.16","EIF2AK2","2","Influenza A; Epstein-Barr virus infection; Herpes simplex infection; Protein processing in endoplasmic reticulum; Viral carcinogenesis; Hepatitis C; Measles","Inhibition of PKR; ISG15 antiviral mechanism","Translation Factors; Type II interferon signaling (IFNG)",20,0,0.839,-0.25,0.00768370838546062,0.147790105890611,96.5,92.9,110.7,"",19.04,9.02,3384.2,"","",3151.4,3192.1,3324.3,4570.2,3709.1,3348.9,4065,4065.2,171.7,"","",2514.8,2416.1,2639.8,3309.9,2671.4,3348.9,3313,3243.9,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q9ULJ7","Ankyrin repeat domain-containing protein 50 OS=Homo sapiens OX=9606 GN=ANKRD50 PE=1 SV=4",0,57.619,9,10,11,10,1429,155.8,6.6,41.41,10,"transport","endosome","protein binding","Pf00023, Pf12796, Pf13191, Pf13606, Pf13637, Pf13857","57182","ENSG00000151458.11","ANKRD50","4","","","",0,0,1.23,0.3,0.00770040740938649,0.147960625786869,98,111.4,90.6,"",10.21,6.32,624.8,"","",715.2,724.5,705.3,576.9,574.4,621,580.6,531.8,31.7,"","",570.7,548.4,560.1,417.8,413.7,621,473.2,424.4,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q8N1I0","Dedicator of cytokinesis protein 4 OS=Homo sapiens OX=9606 GN=DOCK4 PE=1 SV=3",0,20.287,4,6,7,6,1966,225.1,7.65,22.1,6,"cellular component movement;regulation of biological process;response to stimulus","cytoplasm;cytosol;Golgi;membrane","enzyme regulator activity;protein binding","Pf00018, Pf06920, Pf07653, Pf14429","9732","ENSG00000128512.20","DOCK4","7","Rap1 signaling pathway","Factors involved in megakaryocyte development and platelet production","",3,0,1.294,0.37,0.00793223055165648,0.151951288701509,125,98.7,76.3,"",5.82,5.98,250.3,"","",194.2,206.9,201.1,180.5,153.1,170.7,150.8,152.3,12.7,"","",155,156.6,159.7,130.7,110.3,170.7,122.9,121.5,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q5FBB7","Shugoshin 1 OS=Homo sapiens OX=9606 GN=SGO1 PE=1 SV=1",0,21.854,13,4,6,4,561,64.2,9.16,19.93,4,"cell division;cell organization and biogenesis","chromosome;cytoplasm;cytoskeleton;cytosol;nucleus","protein binding","Pf07557, Pf07558","151648","ENSG00000129810.14","SGOL1; SGO1","3","Oocyte meiosis","Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal; Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins","",17,0,0.77,-0.38,0.00823783917879406,0.15653551952622,106.3,84.3,109.4,"",11.49,7.37,264.1,"","",202.6,214.2,256.5,204.5,257.6,258.5,285.8,298.3,13.4,"","",161.7,162.1,203.7,148.1,185.5,258.5,232.9,238,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q13867","Bleomycin hydrolase OS=Homo sapiens OX=9606 GN=BLMH PE=1 SV=1",0,61.783,26,15,18,15,455,52.5,6.27,53.81,15,"metabolic process;response to stimulus","cytoplasm;cytosol;nucleus","catalytic activity;protein binding","Pf03051","642","ENSG00000108578.14","BLMH","17","","Antigen processing: Ubiquitination & Proteasome degradation","",4,0,1.187,0.25,0.00834064694118286,0.158329788366896,104.9,105.9,89.2,"",6.32,3.87,3646.3,"","",3730.9,3629.7,3749.9,3262,3043.5,3008,3274.2,3160.5,185,"","",2977.3,2747.3,2977.8,2362.5,2192,3008,2668.5,2522,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P17931","Galectin-3 OS=Homo sapiens OX=9606 GN=LGALS3 PE=1 SV=5",0,77.754,39,13,40,13,250,26.1,8.56,119.94,13,"cell differentiation;cellular component movement;defense response;metabolic process;regulation of biological process;response to stimulus;transport","cytoplasm;extracellular;membrane;nucleus;spliceosomal complex","protein binding;RNA binding","Pf00337","3958","ENSG00000131981.15","LGALS3","14","","RUNX2 regulates genes involved in differentiation of myeloid cells; Advanced glycosylation endproduct receptor signaling; Neutrophil degranulation; RUNX1 regulates transcription of genes involved in differentiation of myeloid cells","AGE/RAGE pathway; Spinal Cord Injury",13,0,0.851,-0.23,0.008366408883278,0.158500231682402,97.8,92.9,109.3,"",1.85,4.66,7062,"","",6605.2,6709.3,6712.8,6903.5,8319,7990.3,7789,7441.8,358.3,"","",5271,5078.3,5330.6,4999.8,5991.6,7990.3,6348.1,5938.4,"High","High","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P83881","60S ribosomal protein L36a OS=Homo sapiens OX=9606 GN=RPL36A PE=1 SV=2",0,35.705,48,8,24,2,106,12.4,10.58,61.01,8,"cell organization and biogenesis;metabolic process;transport","cytoplasm;cytosol;membrane;ribosome","protein binding;RNA binding;structural molecule activity","Pf00935","6173","ENSG00000241343.9","RPL36A","X","Ribosome","Peptide chain elongation; Eukaryotic Translation Termination; Viral mRNA Translation; L13a-mediated translational silencing of Ceruloplasmin expression; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); Selenocysteine synthesis; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; Regulation of expression of SLITs and ROBOs; Formation of a pool of free 40S subunits; SRP-dependent cotranslational protein targeting to membrane","Cytoplasmic Ribosomal Proteins",34,7,0.845,-0.24,0.00837706524088233,0.158543094458703,194.9,48.1,56.9,119.77,48.49,10.99,3664.1,"",44212.1,3027.6,3043.9,3243.1,7073.2,3621.5,3026.6,3901.4,3818,185.9,"",5.6,2416,2303.9,2575.3,5122.7,2608.3,3026.6,3179.7,3046.7,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q2PPJ7","Ral GTPase-activating protein subunit alpha-2 OS=Homo sapiens OX=9606 GN=RALGAPA2 PE=1 SV=2",0,32.843,5,7,7,6,1873,210.6,6.07,21.48,7,"regulation of biological process","cytoplasm;cytosol;membrane;nucleus","enzyme regulator activity;protein binding","Pf02145","57186","ENSG00000188559.13","RALGAPA2","20","","Translocation of GLUT4 to the plasma membrane","",3,0,1.286,0.36,0.00845847995183369,0.158968924706701,121.6,100.4,78.1,"",3.85,7.2,415.9,"","",345.9,340.7,347.9,319.5,250.5,251.4,285,283.6,21.1,"","",276,257.9,276.3,231.4,180.4,251.4,232.3,226.3,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q96F10","Diamine acetyltransferase 2 OS=Homo sapiens OX=9606 GN=SAT2 PE=1 SV=1",1E-3,4.877,10,2,3,2,170,19.1,6.04,6.67,2,"metabolic process","cytoplasm","catalytic activity;protein binding","Pf00583, Pf08445, Pf13508, Pf13673, Pf14542","112483","ENSG00000141504.11","SAT2","17","Arginine and proline metabolism; Metabolic pathways","","",2,0,0.768,-0.38,0.00844145170655941,0.158968924706701,92.6,90.1,117.3,"",8.52,9.64,177.4,"","",178.6,166.5,167,198.8,236.9,223.1,226.6,188.4,9,"","",142.5,126,132.6,144,170.6,223.1,184.7,150.3,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P08779","Keratin, type I cytoskeletal 16 OS=Homo sapiens OX=9606 GN=KRT16 PE=1 SV=4",0,156.091,53,31,99,14,473,51.2,5.05,237.33,31,"cell death;cell differentiation;cell organization and biogenesis;cell proliferation;cellular component movement;defense response;regulation of biological process;response to stimulus","cytoskeleton;cytosol;nucleus","protein binding;structural molecule activity","Pf00038, Pf07888, Pf13514","3868","ENSG00000186832.8","KRT16","17","","Formation of the cornified envelope","",3,0,1.224,0.29,0.00857108580343313,0.160393733566382,82.2,119.8,97.9,"",8.5,11.55,449.4,"","",555.6,674.6,661.1,649,458.6,528.4,609.2,542.1,22.8,"","",443.4,510.6,525,470,330.3,528.4,496.5,432.6,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P48449","Lanosterol synthase OS=Homo sapiens OX=9606 GN=LSS PE=1 SV=1",0,64.25,24,20,22,20,732,83.3,6.61,56.98,20,"metabolic process;regulation of biological process","endoplasmic reticulum;membrane","catalytic activity","Pf00432, Pf09492, Pf13243, Pf13249","4047","ENSG00000160285.14","LSS","21","Metabolic pathways; Steroid biosynthesis","Cholesterol biosynthesis; Activation of gene expression by SREBF (SREBP)","Cholesterol Biosynthesis; Sterol Regulatory Element-Binding Proteins (SREBP) signalling",10,0,1.204,0.27,0.00860594282459326,0.160393733566382,109.2,104.3,86.6,"",7.9,6.1,3739,"","",3608.4,3534.1,3759.6,3113.3,2983.4,2949.2,3047.4,2648.3,189.7,"","",2879.5,2675,2985.5,2254.8,2148.7,2949.2,2483.7,2113.3,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q6ZU35","Cancer-related regulator of actin dynamics OS=Homo sapiens OX=9606 GN=CRAD PE=1 SV=3",0,25.054,8,7,9,7,1233,136.7,5.6,23.57,7,"","","","Pf15262","57482","ENSG00000109265.13","KIAA1211","4","","","",0,0,1.274,0.35,0.00859246250976287,0.160393733566382,119.3,101.2,79.5,"",5.94,6.41,384.3,"","",338,304.9,346.3,314.8,245.8,255.9,256.3,284.6,19.5,"","",269.7,230.8,275,228,177,255.9,208.9,227.1,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P30305","M-phase inducer phosphatase 2 OS=Homo sapiens OX=9606 GN=CDC25B PE=1 SV=2",0,18.319,9,6,6,5,580,64.9,6.4,15.11,6,"cell division;cell organization and biogenesis;metabolic process;regulation of biological process","cytoplasm;cytoskeleton;cytosol;nucleus","catalytic activity;protein binding","Pf00581, Pf06617","994","ENSG00000101224.17","CDC25B","20","MicroRNAs in cancer; Cell cycle; Progesterone-mediated oocyte maturation; MAPK signaling pathway","Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models; Cyclin A:Cdk2-associated events at S phase entry; Cyclin A/B1/B2 associated events during G2/M transition","Cell Cycle; Integrated Cancer pathway; Retinoblastoma (RB) in Cancer; MAPK Signaling Pathway; Senescence and Autophagy in Cancer",19,1,0.783,-0.35,0.00863938173170853,0.160393733566382,97.6,88.9,113.5,"",6.67,6.29,268.1,"","",257.4,231.3,258.5,228.4,303.2,320.2,324.3,281.8,13.6,"","",205.4,175.1,205.3,165.4,218.4,320.2,264.3,224.9,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q96PY6","Serine/threonine-protein kinase Nek1 OS=Homo sapiens OX=9606 GN=NEK1 PE=1 SV=2",0,8.89,2,2,2,2,1258,142.7,5.94,5.7,2,"cell division;cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus","cytoplasm;cytoskeleton;nucleus","catalytic activity;metal ion binding;nucleotide binding;protein binding","Pf00069, Pf07714, Pf14531","4750","ENSG00000137601.16","NEK1","4","","","",0,0,0.756,-0.4,0.00865317738797877,0.160393733566382,90,90.4,119.6,"",7.8,10.05,61.1,"","",61.9,60.9,66.4,54.8,78.2,74.5,84.4,93.5,3.1,"","",49.4,46.1,52.7,39.7,56.3,74.5,68.8,74.6,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q8N5I2","Arrestin domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ARRDC1 PE=1 SV=1",0,8.71,6,2,2,2,433,46,7.02,5.43,2,"metabolic process;regulation of biological process;transport","membrane","protein binding","Pf00339, Pf02752, Pf03643","92714","ENSG00000197070.13","ARRDC1","9","","","",0,0,0.805,-0.31,0.00868738038034467,0.160398084676393,78.1,98.9,122.9,"",6.21,3.29,331.1,"","",402.1,435.9,403.4,456.2,532.5,509.6,535.6,500.8,16.8,"","",320.9,329.9,320.3,330.4,383.5,509.6,436.5,399.6,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P31276","Homeobox protein Hox-C13 OS=Homo sapiens OX=9606 GN=HOXC13 PE=1 SV=3",2E-3,3.802,3,1,1,1,330,35.4,8.95,3.7,1,"development;metabolic process;regulation of biological process","nucleus","DNA binding;protein binding","Pf00046, Pf05920","3229","ENSG00000123364.4","HOXC13","12","","","",0,0,0.734,-0.45,0.00868610222323163,0.160398084676393,"",127,173,"",15.12,11.47,"","","",40,43.3,45,56.1,70.8,62.3,54.5,58,"","","",31.9,32.8,35.7,40.6,51,62.3,44.4,46.3,"Not Found","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"Medium","Master Protein","Q6UWS5","Protein PET117 homolog, mitochondrial OS=Homo sapiens OX=9606 GN=PET117 PE=3 SV=1",0.026,1.747,14,1,1,1,81,9.2,10.1,2.43,1,"cell organization and biogenesis","mitochondrion","","","100303755","ENSG00000232838.3","PET117","20","","","",0,0,1.42,0.51,0.00868680806146083,0.160398084676393,"",176.1,123.9,"",10.32,13.82,"","","",35.7,34,35.1,42.4,30,22.3,23.2,26.8,"","","",28.5,25.7,27.9,30.7,21.6,22.3,18.9,21.4,"Not Found","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q9BUK0","Coiled-coil-helix-coiled-coil-helix domain-containing protein 7 OS=Homo sapiens OX=9606 GN=CHCHD7 PE=1 SV=1",0,14.631,42,3,3,3,85,10.1,8.82,10.51,3,"","mitochondrion","catalytic activity;transporter activity","Pf02297, Pf06747","79145","ENSG00000170791.17","CHCHD7","8","","Mitochondrial protein import; Metabolism of proteins","",2,0,1.273,0.35,0.00875153357069158,0.161110103394954,122.5,99.4,78.1,"",6.36,5.13,551.9,"","",441.6,412.6,481.2,453.9,330.2,357.6,346,372.8,28,"","",352.4,312.3,382.1,328.7,237.8,357.6,282,297.5,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q9HD33","39S ribosomal protein L47, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL47 PE=1 SV=2",0,39.589,26,8,13,8,250,29.4,10.37,37.95,8,"cell organization and biogenesis;metabolic process","membrane;mitochondrion;ribosome","structural molecule activity","Pf06984","57129","ENSG00000136522.13","MRPL47","3","","Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination","",6,0,1.222,0.29,0.00880101336708283,0.161565163683279,98,111.1,90.9,"",2.92,6.5,1714.8,"","",1914.9,1976.6,1902.4,2025.2,1711.4,1584.7,1459.1,1598.3,87,"","",1528.1,1496.1,1510.7,1466.7,1232.6,1584.7,1189.2,1275.4,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","O15254","Peroxisomal acyl-coenzyme A oxidase 3 OS=Homo sapiens OX=9606 GN=ACOX3 PE=1 SV=2",0,23.068,13,7,7,7,700,77.6,7.25,19.68,7,"metabolic process","membrane;mitochondrion;organelle lumen","catalytic activity;nucleotide binding;protein binding","Pf00441, Pf01756, Pf02770, Pf14749","8310","ENSG00000087008.15","ACOX3","4","Fatty acid metabolism; PPAR signaling pathway; Metabolic pathways; Peroxisome; Biosynthesis of unsaturated fatty acids; Fatty acid degradation; cAMP signaling pathway; alpha-Linolenic acid metabolism","Beta-oxidation of pristanoyl-CoA","PPAR signaling pathway",14,0,1.227,0.29,0.00881046794757401,0.161565163683279,101.7,109.3,89.1,"",4.28,3.01,796.3,"","",863,848.1,870.5,790.8,707,707.9,687.8,663.7,40.4,"","",688.7,641.9,691.3,572.7,509.2,707.9,560.6,529.6,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q9H4H8","Protein FAM83D OS=Homo sapiens OX=9606 GN=FAM83D PE=1 SV=3",0,49.707,23,12,14,12,585,64.4,6.54,43.08,12,"cell division;cell organization and biogenesis;cell proliferation;cellular component movement;regulation of biological process","cytoplasm;cytoskeleton","protein binding","Pf07894, Pf13091","81610","ENSG00000101447.14","FAM83D","20","","","",0,0,0.83,-0.27,0.00898924001641688,0.164364729361164,94.5,93.2,112.3,"",2.41,4.72,1212.2,"","",1249.5,1193.8,1196,1186.2,1456.3,1422.1,1568.4,1422.9,61.5,"","",997.1,903.6,949.7,859.1,1048.9,1422.1,1278.3,1135.4,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P49720","Proteasome subunit beta type-3 OS=Homo sapiens OX=9606 GN=PSMB3 PE=1 SV=2",0,56.454,36,8,21,8,205,22.9,6.55,68.03,8,"metabolic process;regulation of biological process;response to stimulus;transport","cytoplasm;cytosol;nucleus;proteasome","catalytic activity;enzyme regulator activity;protein binding","Pf00227","5691","ENSG00000275903.2; ENSG00000277791.4","PSMB3","17; CHR_HSCHR17_7_CTG4","Proteasome","Regulation of RAS by GAPs; CDT1 association with the CDC6:ORC:origin complex; Downstream TCR signaling; UCH proteinases; NIK-->noncanonical NF-kB signaling; Hh mutants that don't undergo autocatalytic processing are degraded by ERAD; SCF-beta-TrCP mediated degradation of Emi1; Cross-presentation of soluble exogenous antigens (endosomes); Separation of Sister Chromatids; Vpu mediated degradation of CD4; Hedgehog ligand biogenesis; Regulation of RUNX2 expression and activity; Ub-specific processing proteases; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; ER-Phagosome pathway; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; ABC-family proteins mediated transport; Regulation of activated PAK-2p34 by proteasome mediated degradation; CDK-mediated phosphorylation and removal of Cdc6; FCERI mediated NF-kB activation; Neddylation; Autodegradation of the E3 ubiquitin ligase COP1; G2/M Checkpoints; Regulation of RUNX3 expression and activity; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Regulation of expression of SLITs and ROBOs; Removal of licensing factors from origins; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; Regulation of PTEN stability and activity; Regulation of DNA replication; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; Vif-mediated degradation of APOBEC3G; Antigen processing: Ubiquitination & Proteasome degradation; GLI3 is processed to GLI3R by the proteasome; SCF(Skp2)-mediated degradation of p27/p21; APC/C:Cdc20 mediated degradation of Securin; Interleukin-1 family signaling; AUF1 (hnRNP D0) binds and destabilizes mRNA; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; The role of GTSE1 in G2/M progression after G2 checkpoint; Regulation of ornithine decarboxylase (ODC); Interleukin-20 family signaling; Hedgehog 'on' state; Ubiquitin-dependent degradation of Cyclin D1; Degradation of DVL; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Degradation of AXIN; Autodegradation of Cdh1 by Cdh1:APC/C; Asymmetric localization of PCP proteins; Orc1 removal from chromatin; M/G1 Transition; Activation of NF-kappaB in B cells; Degradation of beta-catenin by the destruction complex; MAPK6/MAPK4 signaling; Dectin-1 mediated noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosis","Proteasome Degradation",150,0,0.832,-0.26,9.03563695015119E-3,0.164893826777252,164.5,61.5,73.9,109.97,4.55,4.79,1835,14667.4,"",1946.9,1946,1933.6,1769.7,2304.5,2157.2,2357.1,2415.1,93.1,4.1,"",1553.6,1472.9,1535.5,1281.7,1659.8,2157.2,1921.1,1927.2,"High","High","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q6PD62","RNA polymerase-associated protein CTR9 homolog OS=Homo sapiens OX=9606 GN=CTR9 PE=1 SV=1",0,167.253,28,34,51,34,1173,133.4,6.77,160.57,34,"cell differentiation;cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus","nucleus","protein binding","Pf08424, Pf13414, Pf13424, Pf13432, Pf14559","9646","ENSG00000198730.7","CTR9","11","","E3 ubiquitin ligases ubiquitinate target proteins; Formation of RNA Pol II elongation complex ; RNA Polymerase II Pre-transcription Events","Endoderm Differentiation",10,0,0.852,-0.23,0.00916489494410588,0.165784396783103,93.8,94.9,111.3,"",2.43,1.34,6819.6,"","",6926.9,6877.1,7082.1,6675.8,8169.2,8220.6,8027.4,7995.7,346,"","",5527.7,5205.3,5623.9,4834.9,5883.7,8220.6,6542.4,6380.4,"High","Not Found","High","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q9Y281","Cofilin-2 OS=Homo sapiens OX=9606 GN=CFL2 PE=1 SV=1",0,88.128,63,14,37,10,166,18.7,7.88,102.65,14,"cell organization and biogenesis;cellular homeostasis;regulation of biological process","cytoplasm;cytoskeleton;nucleus","protein binding","Pf00241","1073","ENSG00000165410.14","CFL2","14","Axon guidance; Pertussis; Fc gamma R-mediated phagocytosis; Regulation of actin cytoskeleton","","Leptin signaling pathway; Regulation of Microtubule Cytoskeleton; Regulation of Actin Cytoskeleton; G13 Signaling Pathway",8,0,0.838,-0.25,0.00911917690362962,0.165784396783103,97.7,92.3,110,"",4.18,2.51,2481.5,"","",2312.8,2374.7,2308,2521.1,2764,2786.3,2803.6,2922.6,125.9,"","",1845.6,1797.4,1832.8,1825.9,1990.7,2786.3,2285,2332.2,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q32P44","Echinoderm microtubule-associated protein-like 3 OS=Homo sapiens OX=9606 GN=EML3 PE=1 SV=1",0,61.387,19,17,20,17,896,95.1,7.12,59.66,17,"","cytoplasm;cytoskeleton","protein binding","Pf00400, Pf03451","256364","ENSG00000149499.11","EML3","11","","","",0,0,1.195,0.26,0.00913044953234987,0.165784396783103,101.4,108.1,90.5,"",5.44,4.12,1547.2,"","",1680.4,1618.7,1702.6,1505.2,1464.5,1376.5,1383.2,1326.2,78.5,"","",1341,1225.2,1352,1090.1,1054.8,1376.5,1127.3,1058.3,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P67775","Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform OS=Homo sapiens OX=9606 GN=PPP2CA PE=1 SV=1",0,43.923,36,8,12,1,309,35.6,5.54,41.37,8,"cell death;cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus","chromosome;cytoplasm;cytoskeleton;cytosol;membrane;mitochondrion;nucleus","catalytic activity;metal ion binding;protein binding","Pf00149","5515","ENSG00000113575.9","PPP2CA","5","Oocyte meiosis; AMPK signaling pathway; Tight junction; Dopaminergic synapse; Hepatitis C; mRNA surveillance pathway; Adrenergic signaling in cardiomyocytes; TGF-beta signaling pathway; Sphingolipid signaling pathway; Long-term depression; Hippo signaling pathway; Chagas disease (American trypanosomiasis); PI3K-Akt signaling pathway","Glycolysis; AXIN missense mutants destabilize the destruction complex; PP2A-mediated dephosphorylation of key metabolic factors; APC truncation mutants have impaired AXIN binding; CTLA4 inhibitory signaling; Activated TLR4 signalling; Separation of Sister Chromatids; MASTL Facilitates Mitotic Progression; S37 mutants of beta-catenin aren't phosphorylated; S33 mutants of beta-catenin aren't phosphorylated; S45 mutants of beta-catenin aren't phosphorylated; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); Misspliced GSK3beta mutants stabilize beta-catenin; Cyclin A/B1/B2 associated events during G2/M transition; T41 mutants of beta-catenin aren't phosphorylated; RAF activation; ERKs are inactivated; Beta-catenin phosphorylation cascade; Negative regulation of MAPK pathway; Initiation of Nuclear Envelope Reformation; Platelet sensitization by LDL; Signaling by GPCR; Interleukin-20 family signaling; Spry regulation of FGF signaling; DARPP-32 events; PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling; Regulation of TP53 Degradation; Disassembly of the destruction complex and recruitment of AXIN to the membrane; Cyclin D associated events in G1; Inhibition of replication initiation of damaged DNA by RB1/E2F1; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; Truncations of AMER1 destabilize the destruction complex","TNF alpha Signaling Pathway; Brain-Derived Neurotrophic Factor (BDNF) signaling pathway; Dopamine metabolism; Mesodermal Commitment Pathway; Association Between Physico-Chemical Features and Toxicity Associated Pathways; Focal Adhesion-PI3K-Akt-mTOR-signaling pathway; Wnt Signaling Pathway and Pluripotency; Glycogen Metabolism",145,0,0.782,-0.35,0.00918098681888635,0.165784396783103,96.5,89.3,114.2,"",6.67,5.68,307.5,"","",274.7,278,291.4,317.3,381.7,358,369.9,333.7,15.6,"","",219.2,210.4,231.4,229.8,274.9,358,301.5,266.3,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q9Y4C2","TRPM8 channel-associated factor 1 OS=Homo sapiens OX=9606 GN=TCAF1 PE=1 SV=3",0,39.367,16,14,14,14,921,102.1,6.54,33.83,14,"regulation of biological process;transport","membrane","protein binding","Pf13402","9747","ENSG00000198420.9","FAM115A; TCAF1","7","","","",0,0,0.836,-0.26,0.00917578654729811,0.165784396783103,145.9,70.2,83.9,94.86,4.85,1.6,1833,9301.3,"",1978.4,1993.8,2006.8,1805.8,2384,2322.4,2367.1,2413.4,93,2.6,"",1578.8,1509.1,1593.6,1307.8,1717,2322.4,1929.2,1925.8,"High","High","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q08050","Forkhead box protein M1 OS=Homo sapiens OX=9606 GN=FOXM1 PE=1 SV=3",0,20.885,10,6,6,6,763,84.2,7.91,14.97,6,"cell differentiation;metabolic process;regulation of biological process;response to stimulus","nucleus","DNA binding;protein binding","Pf00250","2305","ENSG00000111206.12","FOXM1","12","","Polo-like kinase mediated events; Cyclin A/B1/B2 associated events during G2/M transition","Sudden Infant Death Syndrome (SIDS) Susceptibility Pathways",7,0,0.759,-0.4,0.00918045983707794,0.165784396783103,117,78.9,104.1,"",6.26,4.66,104.5,"","",69.4,70.8,70.1,79.1,92.5,100.6,90.6,93.4,5.3,"","",55.4,53.6,55.7,57.3,66.6,100.6,73.8,74.5,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","O43663-3","Isoform 3 of Protein regulator of cytokinesis 1 OS=Homo sapiens OX=9606 GN=PRC1",0,132.046,46,27,43,1,525,61.4,7.83,125.28,27,"cell organization and biogenesis;regulation of biological process","cytoskeleton;cytosol;membrane;nucleus","protein binding","Pf03999","9055","ENSG00000198901.13","PRC1","15","","","",0,0,0.768,-0.38,0.00928847924993104,0.167042168551649,75.5,97.5,127,"",5.5,5.15,141.9,"","",183.2,183.2,165.3,187.6,245.5,247.7,232,221.7,7.2,"","",146.2,138.7,131.3,135.9,176.8,247.7,189.1,176.9,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q9BRK5","45 kDa calcium-binding protein OS=Homo sapiens OX=9606 GN=SDF4 PE=1 SV=1",0,69.701,45,13,26,13,362,41.8,4.86,77.94,13,"cell differentiation;response to stimulus;transport","cytoplasm;endosome;Golgi;membrane;organelle lumen","metal ion binding;protein binding","Pf13499","51150","ENSG00000078808.16","SDF4","1","","","",0,0,1.202,0.27,0.00929486018359715,0.167042168551649,110.5,103.4,86.1,"",7.62,2.36,3729.1,"","",3610.1,3374.6,3619.8,3066,2872,2928.4,3022.9,2880.8,189.2,"","",2880.9,2554.2,2874.5,2220.5,2068.5,2928.4,2463.7,2298.8,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q14527","Helicase-like transcription factor OS=Homo sapiens OX=9606 GN=HLTF PE=1 SV=2",0,161.167,29,30,38,30,1009,113.9,8.6,131.06,30,"cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus","cytoplasm;membrane;nucleus","catalytic activity;DNA binding;metal ion binding;nucleotide binding;protein binding;RNA binding","Pf00097, Pf00176, Pf00271, Pf08797, Pf12678, Pf12861, Pf13445, Pf13639, Pf13920, Pf13923, Pf14634, Pf15227","6596","ENSG00000071794.15","HLTF","3","","E3 ubiquitin ligases ubiquitinate target proteins","Retinoblastoma (RB) in Cancer",5,0,0.831,-0.27,0.00931732427829379,0.167286711947161,95.9,92.7,111.5,"",1.02,3.32,3965.6,"","",3816.4,3850.3,3866.2,3778.4,4408.1,4650.3,4772.4,4570.8,201.2,"","",3045.5,2914.3,3070.1,2736.5,3174.8,4650.3,3889.6,3647.4,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","O43491","Band 4.1-like protein 2 OS=Homo sapiens OX=9606 GN=EPB41L2 PE=1 SV=1",0,180.177,39,37,53,35,1005,112.5,5.44,168.29,37,"cell division;cell organization and biogenesis;transport","cytoplasm;cytoskeleton;cytosol;membrane;nucleus","protein binding;structural molecule activity","Pf00373, Pf04382, Pf05902, Pf08736, Pf09379, Pf09380","2037","ENSG00000079819.18","EPB41L2","6","Tight junction","Neurexins and neuroligins","",4,1,1.172,0.23,0.00936958803601984,0.168065317022168,133.3,90,76.8,56.29,0.84,3.16,8498.9,"",19737.5,8863.5,8748.3,8736.5,8690.6,7369.2,7610.4,7087.8,7548.1,431.2,"",2.5,7073.1,6621.6,6937.6,6294.1,5307.5,7610.4,5776.6,6023.2,"High","Not Found","High","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q6ICL3","Transport and Golgi organization protein 2 homolog OS=Homo sapiens OX=9606 GN=TANGO2 PE=1 SV=1",1E-3,4.057,3,1,1,1,276,30.9,5.17,3.24,1,"","Golgi","","Pf05742","128989","ENSG00000183597.15","C22orf25; TANGO2","22","","","",0,0,1.301,0.38,0.00969304095537327,0.17271901657084,117.5,103.2,79.3,"",4.02,4.62,94.6,"","",81.1,86.4,85.3,79.4,65,62.8,69.1,62.7,4.8,"","",64.7,65.4,67.7,57.5,46.8,62.8,56.3,50,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q5SY16","Polynucleotide 5'-hydroxyl-kinase NOL9 OS=Homo sapiens OX=9606 GN=NOL9 PE=1 SV=1",0,49.994,20,10,15,10,702,79.3,9.13,46.53,10,"metabolic process","cytoskeleton;membrane;nucleus","catalytic activity;enzyme regulator activity;nucleotide binding;protein binding;RNA binding","Pf03205, Pf06807","79707","ENSG00000162408.10","NOL9","1","","Major pathway of rRNA processing in the nucleolus and cytosol","",4,0,0.842,-0.25,0.00975577084973978,0.173352901174295,168.6,60.1,71.3,100.42,8.32,1.12,1576.8,9301.3,"",1292.9,1306.6,1424,1540.4,1614.4,1605.6,1647.6,1625.1,80,2.6,"",1031.7,989,1130.8,1115.6,1162.7,1605.6,1342.8,1296.8,"High","High","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q8NFX7","Syntaxin-binding protein 6 OS=Homo sapiens OX=9606 GN=STXBP6 PE=1 SV=2",0,21.266,23,6,7,6,210,23.5,9.04,22.28,6,"regulation of biological process;transport","cytoplasm;membrane","protein binding","Pf00957, Pf15277","29091","ENSG00000168952.15","STXBP6","14","","","",0,0,0.819,-0.29,0.00975614855719376,0.173352901174295,79.1,99.5,121.4,"",2.28,3.14,616.9,"","",771.9,801.4,759.1,779.7,981.4,930.2,964.4,917.1,31.3,"","",616,606.6,602.8,564.7,706.8,930.2,786,731.8,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q8N5M1","ATP synthase mitochondrial F1 complex assembly factor 2 OS=Homo sapiens OX=9606 GN=ATPAF2 PE=1 SV=1",0,5.58,7,2,2,2,289,32.8,7.09,6.88,2,"cell organization and biogenesis","cytosol;mitochondrion","protein binding","Pf07542","91647","ENSG00000171953.15","ATPAF2","17","","","",0,0,1.268,0.34,0.0098294045757219,0.174490407543454,97.9,113,89.1,"",19.57,10.79,232.6,"","",254.9,283,325.1,201,204.9,248.9,219,195.1,11.8,"","",203.4,214.2,258.2,145.6,147.6,248.9,178.5,155.7,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q9H173","Nucleotide exchange factor SIL1 OS=Homo sapiens OX=9606 GN=SIL1 PE=1 SV=1",0,22.242,11,7,8,7,461,52.1,5.36,21.23,7,"metabolic process;transport","endoplasmic reticulum;organelle lumen","protein binding","","64374","ENSG00000120725.12","SIL1","5","Protein processing in endoplasmic reticulum","","",1,0,1.221,0.29,0.00984470852183494,0.17459798550274,97.8,111.1,91,"",9.17,5.94,784.5,"","",919.7,872.1,910.7,748.1,715.5,744.9,782.7,680.6,39.8,"","",733.9,660.1,723.2,541.8,515.3,744.9,637.9,543.1,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q15392","Delta(24)-sterol reductase OS=Homo sapiens OX=9606 GN=DHCR24 PE=1 SV=2",0,44.43,17,8,14,8,516,60.1,8.16,35.37,8,"cell death;cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus","cytoplasm;cytoskeleton;cytosol;endoplasmic reticulum;Golgi;membrane;nucleus","catalytic activity;nucleotide binding;protein binding","Pf01565","1718","ENSG00000116133.11","DHCR24","1","Steroid biosynthesis; Metabolic pathways","Cholesterol biosynthesis via desmosterol; Cholesterol biosynthesis via lathosterol","Tryptophan metabolism",9,0,1.222,0.29,0.00987074575229063,0.174731626775319,190.1,60.4,49.5,110.89,8.7,4.6,2511,20749,"",2351.4,2255.6,2332.6,1936.2,1849,1907.1,1973.7,1770.7,127.4,5.8,"",1876.4,1707.3,1852.3,1402.3,1331.7,1907.1,1608.6,1413,"High","High","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","O00264","Membrane-associated progesterone receptor component 1 OS=Homo sapiens OX=9606 GN=PGRMC1 PE=1 SV=3",0,63.64,44,10,19,9,195,21.7,4.7,69.86,10,"transport","endoplasmic reticulum;membrane","protein binding","Pf00173","10857","ENSG00000101856.9","PGRMC1","X","","Neutrophil degranulation","",3,1,1.188,0.25,0.00999617381551321,0.176786265006941,175.9,67.4,56.7,111.64,13.76,8.04,1389.5,11805.5,"",1551.2,1538.4,1551.1,2004,1512.6,1279.8,1311,1299.8,70.5,3.3,"",1237.9,1164.4,1231.7,1451.4,1089.4,1279.8,1068.5,1037.2,"High","High","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"Medium","Master Protein","Q8N0V3","Putative ribosome-binding factor A, mitochondrial OS=Homo sapiens OX=9606 GN=RBFA PE=1 SV=3",0.031,1.673,3,1,1,1,343,38.3,7.85,2.14,1,"metabolic process","mitochondrion","catalytic activity;protein binding","Pf02033, Pf02637","79863","ENSG00000101546.12","RBFA","18","","","",0,0,1.313,0.39,0.0100397561131378,0.177197004548794,110.5,107.6,82,"",8.45,12.35,78.8,"","",83.8,75.7,77.8,68.2,59.4,70.7,57.5,53.3,4,"","",66.9,57.3,61.8,49.4,42.8,70.7,46.9,42.5,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q9UBC3","DNA (cytosine-5)-methyltransferase 3B OS=Homo sapiens OX=9606 GN=DNMT3B PE=1 SV=1",0,32.113,11,9,10,6,853,95.7,8.43,24.55,9,"metabolic process;regulation of biological process;response to stimulus","cytoplasm;nucleus","catalytic activity;DNA binding;metal ion binding;protein binding","Pf00145, Pf00855","1789","ENSG00000088305.18","DNMT3B","20","Metabolic pathways; Cysteine and methionine metabolism; MicroRNAs in cancer","PRC2 methylates histones and DNA; DNA methylation; NoRC negatively regulates rRNA expression","One Carbon Metabolism; Trans-sulfuration and one carbon metabolism; Mesodermal Commitment Pathway; Hematopoietic Stem Cell Gene Regulation by GABP alpha/beta Complex",13,0,0.771,-0.38,0.0101939017643435,0.177472048136411,92.2,90.5,117.3,"",8.94,7.27,214.8,"","",217.3,200.6,243.4,204.5,281.2,276.3,270.5,238.2,10.9,"","",173.4,151.8,193.3,148.1,202.5,276.3,220.5,190.1,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q9BXS4","Transmembrane protein 59 OS=Homo sapiens OX=9606 GN=TMEM59 PE=1 SV=1",0,30.344,20,6,9,6,323,36.2,5.1,32,6,"metabolic process;regulation of biological process","endosome;Golgi;membrane;vacuole","catalytic activity;protein binding","Pf12280","9528","ENSG00000116209.11","TMEM59","1","","","",0,0,0.826,-0.28,0.0101053160435267,0.177472048136411,105.1,88.1,106.8,"",8.99,4.44,1137.3,"","",914,970.7,937.7,1111.5,1151.6,1070.1,1159.7,1188.1,57.7,"","",729.4,734.7,744.6,805,829.4,1070.1,945.2,948.1,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","O14628","Zinc finger protein 195 OS=Homo sapiens OX=9606 GN=ZNF195 PE=1 SV=2",0,12.515,5,3,3,3,629,72.3,8.09,10.54,3,"metabolic process;regulation of biological process","nucleus","DNA binding;metal ion binding","Pf01352, Pf13465","7748","ENSG00000005801.16","ZNF195","11","","Generic Transcription Pathway","",3,0,0.761,-0.39,0.0101946829853878,0.177472048136411,"",129.6,170.4,"",10.06,6.48,"","","",95.9,90.5,94.8,76.4,112,125.5,129.8,118.2,"","","",76.5,68.5,75.3,55.3,80.7,125.5,105.8,94.3,"Not Found","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P62070","Ras-related protein R-Ras2 OS=Homo sapiens OX=9606 GN=RRAS2 PE=1 SV=1",0,33.833,43,8,13,7,204,23.4,6.01,37.86,8,"cell differentiation;regulation of biological process;response to stimulus","endoplasmic reticulum;membrane","catalytic activity;nucleotide binding;protein binding","Pf00071, Pf08477","22800","ENSG00000133818.13","RRAS2","11","Ras signaling pathway; MAPK signaling pathway; Proteoglycans in cancer; Tight junction; cAMP signaling pathway; Regulation of actin cytoskeleton; HTLV-I infection; Phospholipase D signaling pathway","","Regulation of Actin Cytoskeleton",9,1,0.82,-0.29,0.0102838231589855,0.178694435903328,189.8,49.6,60.5,130.11,4.62,5.63,581.4,13951.9,"",726.3,763.9,766.9,695.1,875.3,989.6,930.5,886.6,29.5,3.9,"",579.6,578.2,609,503.4,630.4,989.6,758.4,707.5,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q15004","PCNA-associated factor OS=Homo sapiens OX=9606 GN=PCLAF PE=1 SV=1",0,77.737,70,8,38,8,111,12,9.83,125.81,8,"cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus","cytoplasm;nucleus","protein binding","","9768","ENSG00000259316.10; ENSG00000166803.11","KIAA0101; PCLAF","15","","Termination of translesion DNA synthesis","",4,0,0.839,-0.25,0.0103755928004254,0.179957940141814,86.3,97.4,116.2,"",9.8,8.11,1949.3,"","",2116.4,2222.6,2177.2,2610.9,2561,2531,2687.3,3009.2,98.9,"","",1688.9,1682.3,1728.9,1890.9,1844.5,2531,2190.2,2401.3,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q96QD9","UAP56-interacting factor OS=Homo sapiens OX=9606 GN=FYTTD1 PE=1 SV=3",0,61.076,53,15,19,15,318,35.8,11.78,49.04,15,"transport","nucleus","protein binding;RNA binding","Pf07078","84248","ENSG00000122068.12","FYTTD1","3","","Cleavage of Growing Transcript in the Termination Region ; Transport of Mature mRNA derived from an Intron-Containing Transcript; mRNA 3'-end processing","",9,0,0.844,-0.25,0.0105244214589328,0.182204649419178,98,92.4,109.6,"",4.13,1.19,2245,"","",2110.5,2123.8,2224.5,2010.5,2514.9,2514.7,2503.9,2452.5,113.9,"","",1684.2,1607.5,1766.5,1456.1,1811.3,2514.7,2040.7,1957,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q9NZN4","EH domain-containing protein 2 OS=Homo sapiens OX=9606 GN=EHD2 PE=1 SV=2",0,33.125,24,10,11,9,543,61.1,6.46,31.49,10,"cell organization and biogenesis;coagulation;regulation of biological process;transport","cytoplasm;cytoskeleton;cytosol;endosome;membrane;nucleus","catalytic activity;metal ion binding;nucleotide binding;protein binding","Pf00350, Pf01926, Pf12763","30846","ENSG00000024422.11","EHD2","19","Endocytosis","Factors involved in megakaryocyte development and platelet production","Insulin Signaling",4,0,0.821,-0.28,0.010550941321559,0.182496501539932,88.3,95.5,116.3,"",4.17,2.41,814,"","",872.3,900.8,818.4,888.5,1043.4,1069.4,1106.5,1075.7,41.3,"","",696.1,681.8,649.9,643.5,751.5,1069.4,901.8,858.4,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q02241-3","Isoform 3 of Kinesin-like protein KIF23 OS=Homo sapiens OX=9606 GN=KIF23",0,156.589,50,32,52,3,673,77.7,7.97,144.31,32,"cell organization and biogenesis;cellular component movement;regulation of biological process;transport","cytosol;nucleus","catalytic activity;motor activity;nucleotide binding;protein binding","Pf00225, Pf02463, Pf05852, Pf11559, Pf12329, Pf15294","9493","ENSG00000137807.13","KIF23","15","","","",0,0,0.77,-0.38,0.0106056307242244,0.182565150773927,88.4,92,119.5,"",8.28,8.97,147.8,"","",162.9,161.2,146.7,136.4,208.8,210.6,191.2,173.1,7.5,"","",130,122,116.5,98.8,150.4,210.6,155.8,138.1,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q9H903","Probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 OS=Homo sapiens OX=9606 GN=MTHFD2L PE=2 SV=3",0.003,3.467,4,2,2,1,347,37.3,9.33,4.72,2,"metabolic process","cytosol;membrane;mitochondrion;organelle lumen","catalytic activity","Pf00763, Pf02882","441024","ENSG00000163738.18","MTHFD2L","4","","Metabolism of folate and pterines","Trans-sulfuration and one carbon metabolism",5,0,0.763,-0.39,0.0106225699227311,0.182565150773927,111.2,81.7,107.1,"",69.53,15.57,94.6,"","",57.6,64.7,74.7,204.6,87.9,66.8,94.6,95.7,4.8,"","",46,49,59.3,148.2,63.3,66.8,77.1,76.4,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","O43670","BUB3-interacting and GLEBS motif-containing protein ZNF207 OS=Homo sapiens OX=9606 GN=ZNF207 PE=1 SV=1",0,32.512,14,6,13,6,478,50.7,9.1,42.34,6,"cell division;cell organization and biogenesis;regulation of biological process","chromosome;cytoplasm;cytoskeleton;nucleus","DNA binding;metal ion binding;protein binding;RNA binding","","7756","ENSG00000010244.18","ZNF207","17","","","",0,0,0.831,-0.27,0.0107360073121836,0.184012437488679,105.6,88.2,106.2,"",42.53,8.57,2085.3,"","",1741.2,1682.7,1741.6,3581.1,2010.6,1842.9,2186.2,2230,105.8,"","",1389.5,1273.6,1383,2593.6,1448.1,1842.9,1781.8,1779.5,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q8NB49","Phospholipid-transporting ATPase IG OS=Homo sapiens OX=9606 GN=ATP11C PE=1 SV=3",0,14.357,5,7,7,6,1132,129.4,6.67,17.43,7,"cell differentiation;cell organization and biogenesis;regulation of biological process;transport","endoplasmic reticulum;endosome;membrane","catalytic activity;metal ion binding;nucleotide binding;protein binding;transporter activity","Pf00122, Pf00702, Pf13246","286410","ENSG00000101974.14","ATP11C","X","","Ion transport by P-type ATPases","",3,0,1.212,0.28,0.0107681118442404,0.184395373086141,108,105.2,86.8,"",2.73,5.46,950,"","",918.2,914.9,933.6,970.5,746.6,814.3,718.1,781.5,48.2,"","",732.7,692.5,741.4,702.9,537.7,814.3,585.3,623.6,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q99873","Protein arginine N-methyltransferase 1 OS=Homo sapiens OX=9606 GN=PRMT1 PE=1 SV=3",0,77.864,40,15,26,15,371,42.4,5.35,75.36,15,"","","","","","","","","","","",0,0,1.187,0.25,0.0108849865010838,0.185723238511718,169.9,70.6,59.5,66.11,3.08,1.86,5114.7,12520.9,22895.5,5200.6,5201.7,5241.8,4900.9,4283.1,4479.7,4366.1,4398,259.5,3.5,2.9,4150.1,3937.2,4162.5,3549.4,3084.8,4479.7,3558.4,3509.5,"High","High","High","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q9UIQ6","Leucyl-cystinyl aminopeptidase OS=Homo sapiens OX=9606 GN=LNPEP PE=1 SV=3",0,84.079,16,15,21,15,1025,117.3,5.73,75,15,"cell communication;cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus","cytosol;extracellular;membrane;organelle lumen","catalytic activity;metal ion binding;protein binding","Pf01433, Pf11838, Pf13485","4012","ENSG00000113441.15","LNPEP","5","Renin-angiotensin system","Translocation of GLUT4 to the plasma membrane; Antigen processing: Ubiquitination & Proteasome degradation; Endosomal/Vacuolar pathway","",10,0,1.204,0.27,0.0110012604950016,0.187199827233865,101.9,108.2,89.9,"",2.47,3.6,1614.2,"","",1720.7,1708.9,1736.4,1641,1407.3,1440.6,1336.8,1447.5,81.9,"","",1373.1,1293.5,1378.9,1188.5,1013.6,1440.6,1089.5,1155.1,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q9UKN8","General transcription factor 3C polypeptide 4 OS=Homo sapiens OX=9606 GN=GTF3C4 PE=1 SV=2",0,134.186,31,22,33,22,822,91.9,6.65,103.78,22,"cell organization and biogenesis;metabolic process;regulation of biological process","mitochondrion;nucleus","catalytic activity;DNA binding;enzyme regulator activity;protein binding","Pf12657, Pf12660","9329","ENSG00000125484.11","GTF3C4","9","","RNA Polymerase III Abortive And Retractive Initiation; RNA Polymerase III Transcription Initiation From Type 1 Promoter; RNA Polymerase III Transcription Initiation From Type 2 Promoter","",6,0,0.842,-0.25,0.0111446623876907,0.189058395618198,96.5,93.1,110.5,"",1.38,2.23,3784.3,"","",3638.6,3559,3668.2,3661.2,4195.5,4288.5,4376.9,4410.2,192,"","",2903.6,2693.8,2912.9,2651.6,3021.7,4288.5,3567.2,3519.2,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q13829","BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 2 OS=Homo sapiens OX=9606 GN=TNFAIP1 PE=1 SV=1",0,10.755,12,5,5,3,316,36.2,8.03,12.6,5,"cell death;cell organization and biogenesis;cellular component movement;metabolic process;regulation of biological process;response to stimulus","cytoplasm;endosome;nucleus","catalytic activity;protein binding","Pf02214","7126","ENSG00000109079.9","TNFAIP1","17","","","",0,0,0.771,-0.38,0.0111705405289024,0.189058395618198,99.3,87.4,113.3,"",4.22,3.1,173.4,"","",158.3,151.7,142.9,153.4,194.8,200.9,204.3,190.6,8.8,"","",126.3,114.8,113.5,111.1,140.3,200.9,166.5,152.1,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q92536","Y+L amino acid transporter 2 OS=Homo sapiens OX=9606 GN=SLC7A6 PE=1 SV=3",1E-3,4.75,2,2,2,2,515,56.8,5.88,4.68,2,"cell organization and biogenesis;cellular component movement;metabolic process;transport","membrane","transporter activity","Pf00324, Pf13520","9057","ENSG00000103064.13","SLC7A6","16","","Basigin interactions; Amino acid transport across the plasma membrane","",7,0,0.711,-0.49,0.0112595799866471,0.190054465404638,"",124.7,175.3,"",20.6,16.79,"","","",25.4,28.3,28.5,39.6,36,46.8,32.6,44.2,"","","",20.3,21.4,22.6,28.7,25.9,46.8,26.6,35.3,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q8NCN4","E3 ubiquitin-protein ligase RNF169 OS=Homo sapiens OX=9606 GN=RNF169 PE=1 SV=2",0,79.61,33,19,19,19,708,77.1,9.1,60.56,19,"metabolic process;regulation of biological process;response to stimulus","nucleus","catalytic activity;metal ion binding;protein binding","Pf00097, Pf13920","254225","ENSG00000166439.5","RNF169","11","","","",0,0,0.82,-0.29,0.0113308593375847,0.19074623098779,84.2,97.2,118.6,"",4.59,1.59,808.1,"","",940.1,884,988.2,927,1150.7,1153.1,1127.1,1116.2,41,"","",750.2,669.1,784.7,671.4,828.8,1153.1,918.6,890.7,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q9Y5Q0","Fatty acid desaturase 3 OS=Homo sapiens OX=9606 GN=FADS3 PE=1 SV=1",0,13.402,14,4,4,4,445,51.1,7.77,12.89,4,"metabolic process;transport","endoplasmic reticulum;membrane","catalytic activity","Pf00173, Pf00487","3995","ENSG00000221968.8","FADS3","11","","","",0,0,0.801,-0.32,0.0113243720699654,0.19074623098779,98.9,89.4,111.6,"",14.67,0.99,443.5,"","",381.1,402,399.6,517.5,501.9,498.9,491.8,502.5,22.5,"","",304.1,304.3,317.3,374.8,361.5,498.9,400.8,401,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P05787","Keratin, type II cytoskeletal 8 OS=Homo sapiens OX=9606 GN=KRT8 PE=1 SV=7",0,695.758,77,60,674,50,483,53.7,5.59,1918.9,60,"cell death;cell differentiation;cell organization and biogenesis;regulation of biological process;response to stimulus","cytoplasm;cytoskeleton;cytosol;membrane;nucleus","catalytic activity;motor activity;protein binding;structural molecule activity","Pf00038, Pf01576, Pf13166, Pf15003","3856","ENSG00000170421.12","KRT8","12","","Formation of the cornified envelope","Primary Focal Segmental Glomerulosclerosis FSGS",4,12,0.856,-0.22,0.0114530109356197,0.191437584559278,40.1,119.9,140,69.7,8.67,7.2,64451.2,22180,20527,62802.8,70223.6,62165.8,74163.1,73134.8,82633,72420.9,82231,3270,6.2,2.6,50116.9,53152.3,49365.6,53712,52673.7,82633,59023.9,65618.3,"High","High","High","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q9H0P0-1","Isoform 1 of Cytosolic 5'-nucleotidase 3A OS=Homo sapiens OX=9606 GN=NT5C3A",0,44.37,41,11,13,1,297,33.9,5.86,39.71,11,"defense response;metabolic process;response to stimulus","cytoplasm;cytosol;endoplasmic reticulum;mitochondrion","catalytic activity;metal ion binding;nucleotide binding","Pf05822, Pf12710","51251","ENSG00000122643.18","NT5C3; NT5C3A","7","","","",0,0,0.771,-0.38,0.0114194809592285,0.191437584559278,70.1,100.1,129.8,"",6.65,5.78,104.5,"","",133.2,151.4,147.1,155.7,175.6,200.6,197.1,190.1,5.3,"","",106.3,114.6,116.8,112.8,126.5,200.6,160.6,151.7,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q9BZM1","Group XIIA secretory phospholipase A2 OS=Homo sapiens OX=9606 GN=PLA2G12A PE=1 SV=1",0,15.826,12,3,4,3,189,21.1,7.24,15.55,3,"metabolic process;transport","cytoplasm;endoplasmic reticulum;extracellular;Golgi","catalytic activity;metal ion binding","Pf06951","81579","ENSG00000123739.10","PLA2G12A","4","Fat digestion and absorption; alpha-Linolenic acid metabolism; Pancreatic secretion; Vascular smooth muscle contraction; Metabolic pathways; Glycerophospholipid metabolism; Arachidonic acid metabolism; Ras signaling pathway; Linoleic acid metabolism; Ether lipid metabolism","Acyl chain remodelling of PI; Synthesis of PA; Acyl chain remodelling of PG; Acyl chain remodelling of PS; Acyl chain remodelling of PE; Acyl chain remodelling of PC","",20,0,1.269,0.34,0.011438882843011,0.191437584559278,136.8,91.3,71.9,"",10.44,3.16,599.2,"","",394.6,404.7,436.8,338.1,323.9,314,315.9,300.1,30.4,"","",314.9,306.3,346.9,244.9,233.3,314,257.5,239.5,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q13641","Trophoblast glycoprotein OS=Homo sapiens OX=9606 GN=TPBG PE=1 SV=1",0,14.096,10,4,5,4,420,46,6.83,13.18,4,"regulation of biological process","cell surface;cytoplasm;endoplasmic reticulum;membrane","protein binding","Pf01462, Pf12799, Pf13855","7162","ENSG00000283085.1; ENSG00000146242.8","TPBG","6; CHR_HG2072_PATCH","","","",0,0,1.205,0.27,0.0114816844645822,0.191577788133417,98.7,110,91.3,"",4.67,4.95,1285.1,"","",1459,1405.6,1481.1,1332.2,1198.5,1287.9,1149.3,1179.4,65.2,"","",1164.3,1063.9,1176.1,964.8,863.2,1287.9,936.7,941.1,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q6P0N0","Mis18-binding protein 1 OS=Homo sapiens OX=9606 GN=MIS18BP1 PE=1 SV=1",0,81.465,20,20,21,20,1132,129,9.25,69.83,20,"cell division;cell organization and biogenesis","chromosome;nucleus","DNA binding;protein binding","Pf00249, Pf09133","55320","ENSG00000129534.13","MIS18BP1","14","","Deposition of new CENPA-containing nucleosomes at the centromere","",4,0,0.839,-0.25,0.0114947252466309,0.191626099257161,99.3,91.6,109.2,"",3.46,2.22,1896.1,"","",1786,1712,1837.7,1713.5,2137,2065.1,2030.9,2105.7,96.2,"","",1425.2,1295.8,1459.3,1241,1539.1,2065.1,1655.2,1680.3,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P35237","Serpin B6 OS=Homo sapiens OX=9606 GN=SERPINB6 PE=1 SV=3",0,127.37,52,18,47,17,376,42.6,5.27,140.64,18,"regulation of biological process;response to stimulus;transport","cytoplasm;cytosol;extracellular;membrane;nucleus","enzyme regulator activity;protein binding","Pf00079","5269","ENSG00000124570.17","SERPINB6","6","Amoebiasis","Dissolution of Fibrin Clot; Neutrophil degranulation","Ectoderm Differentiation",7,0,1.167,0.22,0.0115194897816626,0.191869596998275,101.2,107.1,91.7,"",2.45,1.81,7479.9,"","",7926,8029.7,7895.6,7582.4,6743.1,6838.9,6569.1,6813.9,379.5,"","",6325,6077.7,6269.9,5491.5,4856.6,6838.9,5353.9,5437.3,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q96GX2","Ataxin-7-like protein 3B OS=Homo sapiens OX=9606 GN=ATXN7L3B PE=1 SV=2",0,19.448,25,1,3,1,97,10.8,4.36,13.07,1,"","cytoplasm","","","552889","ENSG00000253719.3","ATXN7L3B","12","","","",0,0,1.362,0.45,0.0115897375594036,0.192869570944507,"",173,127,"",31.05,22.43,"","","",50.3,54.2,37,77.9,50.4,42.1,30.2,34.8,"","","",40.1,41,29.4,56.4,36.3,42.1,24.6,27.8,"Not Found","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q8WVX9","Fatty acyl-CoA reductase 1 OS=Homo sapiens OX=9606 GN=FAR1 PE=1 SV=1",0,46.074,22,11,14,11,515,59.3,9.17,40.59,11,"metabolic process","membrane;organelle lumen","catalytic activity","Pf01370, Pf03015, Pf07993","84188","ENSG00000197601.12","FAR1","11","Peroxisome","Wax biosynthesis","",4,0,0.839,-0.25,0.0116000090044777,0.192870572250505,163.8,62.2,74.1,101.27,10.4,5.65,1894.1,11447.7,"",1799.4,1735.6,1921.2,1491.9,1944.7,2179,2188.1,2034.8,96.1,3.2,"",1435.9,1313.7,1525.6,1080.5,1400.6,2179,1783.3,1623.7,"High","High","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q86YM7","Homer protein homolog 1 OS=Homo sapiens OX=9606 GN=HOMER1 PE=1 SV=2",0,8.318,8,3,3,2,354,40.3,5.44,9.55,3,"cell communication;metabolic process;regulation of biological process;response to stimulus","cytoplasm;cytosol;membrane","protein binding","Pf00568, Pf04111, Pf04156","9456","ENSG00000152413.14","HOMER1","5","FoxO signaling pathway; Glutamatergic synapse","Neurexins and neuroligins","BDNF-TrkB Signaling",6,0,1.349,0.43,0.0119539305013394,0.198057753780087,110.4,108.9,80.7,"",10.33,8.76,49.3,"","",49.9,47.3,52.5,41,35.5,32.8,40.5,36.5,2.5,"","",39.8,35.8,41.7,29.7,25.6,32.8,33,29.1,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P07099","Epoxide hydrolase 1 OS=Homo sapiens OX=9606 GN=EPHX1 PE=1 SV=1",0,56.062,28,13,19,13,455,52.9,7.25,54.89,13,"metabolic process;response to stimulus","endoplasmic reticulum;membrane","catalytic activity;protein binding","Pf00561, Pf06441, Pf12697","2052","ENSG00000143819.12","EPHX1","1","Metabolism of xenobiotics by cytochrome P450; Bile secretion; Chemical carcinogenesis","Phase I - Functionalization of compounds","Photodynamic therapy-induced NFE2L2 (NRF2) survival signaling; Benzene metabolism; Benzo(a)pyrene metabolism; Aflatoxin B1 metabolism; Metapathway biotransformation",11,0,0.845,-0.24,0.0120089058265602,0.198297522299687,91.2,95.6,113.2,"",3.11,2.57,1976.9,"","",2016.5,2171.5,2065.2,2081.4,2485.7,2514.1,2374,2423,100.3,"","",1609.2,1643.6,1640,1507.4,1790.3,2514.1,1934.8,1933.5,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P48730","Casein kinase I isoform delta OS=Homo sapiens OX=9606 GN=CSNK1D PE=1 SV=2",0,32.126,22,9,10,1,415,47.3,9.74,25.71,9,"cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus;transport","cytoplasm;cytoskeleton;cytosol;Golgi;membrane;nucleus","catalytic activity;nucleotide binding;protein binding","Pf00069, Pf01636, Pf07714","1453","ENSG00000141551.14","CSNK1D","17","Hippo signaling pathway; Hedgehog signaling pathway; Circadian rhythm; Gap junction","Regulation of PLK1 Activity at G2/M Transition; AURKA Activation by TPX2; Anchoring of the basal body to the plasma membrane; COPII (Coat Protein 2) Mediated Vesicle Transport; Recruitment of NuMA to mitotic centrosomes; Recruitment of mitotic centrosome proteins and complexes; Loss of Nlp from mitotic centrosomes; Circadian Clock; Major pathway of rRNA processing in the nucleolus and cytosol","Integrated Breast Cancer Pathway; Melatonin metabolism and effects; Wnt Signaling Pathway Netpath",36,6,0.837,-0.26,0.0120523907030941,0.198297522299687,95.6,93.1,111.2,"",18.37,13.2,1537.4,"","",1416.9,1388.7,1582.7,2026.7,1652.9,1468.1,1942.5,1934.3,78,"","",1130.7,1051.1,1256.8,1467.8,1190.5,1468.1,1583.2,1543.5,"Not Found","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P55347","Homeobox protein PKNOX1 OS=Homo sapiens OX=9606 GN=PKNOX1 PE=1 SV=3",0,5.641,11,2,2,2,436,47.6,4.91,6.15,2,"cell differentiation;metabolic process;regulation of biological process","cytoplasm;cytosol;nucleus","DNA binding;protein binding","Pf00046, Pf05920","5316","ENSG00000160199.14","PKNOX1","21","","Activation of anterior HOX genes in hindbrain development during early embryogenesis","Sudden Infant Death Syndrome (SIDS) Susceptibility Pathways",4,0,0.723,-0.47,0.0120470630119047,0.198297522299687,"",125.9,174.1,"",15.83,8.94,"","","",29.2,26.8,31.6,38.4,45,42.9,36.3,41.1,"","","",23.3,20.3,25.1,27.8,32.4,42.9,29.6,32.8,"Not Found","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","O43169","Cytochrome b5 type B OS=Homo sapiens OX=9606 GN=CYB5B PE=1 SV=3",0,22.194,18,3,6,3,150,16.7,4.97,24.28,3,"","","","","","","","","","","",0,0,1.229,0.3,0.0121088739317057,0.198707568046965,88.4,116.7,94.9,"",3.7,11.61,392.2,"","",530.3,514.1,486.2,520.7,418.2,396.8,423.6,511.8,19.9,"","",423.2,389.1,386.1,377.1,301.2,396.8,345.2,408.4,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"Low","Master Protein","P52450","DNA replication helicase OS=Human herpesvirus 6B (strain Z29) OX=36351 GN=HELI PE=3 SV=1",0.077,1.173,1,1,1,1,824,93.3,5.8,2.77,1,"metabolic process","","catalytic activity;nucleotide binding","Pf02689","1497077","","U77","","","","",0,0,1.27,0.34,0.012103539700469,0.198707568046965,97.4,113.3,89.2,"",10.19,8.1,177.4,"","",221.1,212.8,200,174,151.3,152.8,172.8,176.8,9,"","",176.4,161.1,158.8,126,109,152.8,140.8,141.1,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q9H0F6","Sharpin OS=Homo sapiens OX=9606 GN=SHARPIN PE=1 SV=1",0,10.258,12,4,4,4,387,39.9,5.8,4.91,4,"cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus","cytoplasm;cytosol","catalytic activity;metal ion binding;protein binding","","81858","ENSG00000179526.16","SHARPIN","8","NOD-like receptor signaling pathway","Regulation of TNFR1 signaling; TNFR1-induced NFkappaB signaling pathway; Neurexins and neuroligins","",9,0,1.281,0.36,0.012258704777238,0.200643341275972,109.2,107.2,83.7,"",26.08,9.46,151.8,"","",164.2,139.6,158.9,85.9,111.6,103.2,121.2,128.3,7.7,"","",131,105.7,126.2,62.2,80.4,103.2,98.8,102.4,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q9UBV7","Beta-1,4-galactosyltransferase 7 OS=Homo sapiens OX=9606 GN=B4GALT7 PE=1 SV=1",0.004,3.035,5,2,2,2,327,37.4,8.98,5.03,2,"cell organization and biogenesis;metabolic process;regulation of biological process","Golgi;membrane","catalytic activity;metal ion binding;protein binding","Pf02709, Pf13733","11285","ENSG00000027847.13","B4GALT7","5","Glycosaminoglycan biosynthesis - heparan sulfate / heparin; Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate; Metabolic pathways","A tetrasaccharide linker sequence is required for GAG synthesis; Defective B4GALT7 causes EDS, progeroid type","",13,0,1.288,0.37,0.0124867212083084,0.204198433058467,122,100.2,77.8,"",19.64,14.95,114.3,"","",99.2,92.6,95.2,61.9,68.3,73,94,72.8,5.8,"","",79.2,70.1,75.6,44.8,49.2,73,76.6,58.1,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q5T2R2","Decaprenyl-diphosphate synthase subunit 1 OS=Homo sapiens OX=9606 GN=PDSS1 PE=1 SV=1",0,9.239,7,3,3,3,415,46.2,9,5.25,3,"cell organization and biogenesis;metabolic process","mitochondrion;organelle lumen","catalytic activity;metal ion binding;protein binding","Pf00348","23590","ENSG00000148459.15","PDSS1","10","Terpenoid backbone biosynthesis","Ubiquinol biosynthesis","",5,0,1.273,0.35,0.0126234216407737,0.205500132667117,111.5,105.6,83,"",8.68,7.03,262.1,"","",273.4,247.7,248.8,220.8,215.8,201.9,185.4,188.5,13.3,"","",218.2,187.5,197.6,159.9,155.4,201.9,151.1,150.4,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q6ICB4","Sesquipedalian-2 OS=Homo sapiens OX=9606 GN=PHETA2 PE=1 SV=1",0,7.452,9,2,2,2,259,28.3,7.11,6.43,2,"cell organization and biogenesis;metabolic process;transport","cytosol;endosome;Golgi","protein binding","Pf00169","150368","ENSG00000177096.8","FAM109B","22","","","",0,0,0.717,-0.48,0.0126949281171695,0.206352669773751,116.2,76.7,107.1,"",17.69,10.36,41.4,"","",26.9,27.7,33.9,22,40.1,31.7,39.5,36.8,2.1,"","",21.5,21,26.9,15.9,28.9,31.7,32.2,29.4,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q9P2J9","[Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 2, mitochondrial OS=Homo sapiens OX=9606 GN=PDP2 PE=2 SV=2",0,5.395,4,2,2,2,529,59.9,6.07,5.99,2,"metabolic process;regulation of biological process","mitochondrion;organelle lumen","catalytic activity;metal ion binding","Pf00481","57546","ENSG00000172840.6","PDP2","16","","Regulation of pyruvate dehydrogenase (PDH) complex","",5,0,1.268,0.34,0.0127766497380979,0.207502459375058,102.2,110.6,87.2,"",6.22,5.96,214.8,"","",228.6,244,236.5,210.7,197.3,189.1,177.7,173.1,10.9,"","",182.4,184.7,187.8,152.6,142.1,189.1,144.8,138.1,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q9NPC8","Homeobox protein SIX2 OS=Homo sapiens OX=9606 GN=SIX2 PE=1 SV=1",0,6.677,11,3,3,3,291,32.3,9.01,6.02,3,"cell differentiation;cell organization and biogenesis;cell proliferation;cellular component movement;development;metabolic process;regulation of biological process;transport","nucleus","DNA binding;protein binding","Pf00046, Pf05920","10736","ENSG00000170577.7","SIX2","2","","","",0,0,0.783,-0.35,0.0130564267335522,0.210957902603366,103.5,86.3,110.2,"",13.64,13.98,181.3,"","",170.2,140.7,162.6,125.5,151.9,181.3,205.9,207.5,9.2,"","",135.8,106.5,129.1,90.9,109.4,181.3,167.8,165.6,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q13526","Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 OS=Homo sapiens OX=9606 GN=PIN1 PE=1 SV=1",0,48.351,56,8,15,8,163,18.2,8.82,40.92,8,"cell differentiation;cell organization and biogenesis;cellular component movement;metabolic process;regulation of biological process;response to stimulus;transport","cytoplasm;cytosol;mitochondrion;nucleus","catalytic activity;motor activity;protein binding;transporter activity","Pf00397, Pf00639, Pf13616","5300","ENSG00000127445.13","PIN1","19","RIG-I-like receptor signaling pathway","ISG15 antiviral mechanism; PI5P Regulates TP53 Acetylation; Negative regulators of DDX58/IFIH1 signaling; Regulation of TP53 Activity through Phosphorylation","RIG-I-like Receptor Signaling",18,0,0.844,-0.24,0.0130967725074251,0.211130827710685,95.7,93.5,110.8,"",32.32,12.9,1326.5,"","",1254.1,1215.5,1339.6,2242.2,1534.2,1184.5,1537.9,1599.9,67.3,"","",1000.8,920,1063.8,1623.9,1105,1184.5,1253.4,1276.7,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P61968","LIM domain transcription factor LMO4 OS=Homo sapiens OX=9606 GN=LMO4 PE=1 SV=1",1E-3,4.006,10,2,2,2,165,18,8.34,5.21,2,"cell differentiation;metabolic process;regulation of biological process","","DNA binding;metal ion binding;protein binding","Pf00412","8543","ENSG00000143013.12","LMO4","1","","","",0,0,0.781,-0.36,0.0131662484309327,0.21180749374056,122.6,77.8,99.6,"",35.33,23.14,246.4,"","",149.4,124.5,163.5,265.7,184.5,137.5,216.8,242.2,12.5,"","",119.2,94.2,129.8,192.4,132.9,137.5,176.7,193.3,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"Medium","Master Protein","Q8N568","Serine/threonine-protein kinase DCLK2 OS=Homo sapiens OX=9606 GN=DCLK2 PE=1 SV=4",0.04,1.568,1,1,1,1,766,83.6,8.34,2.11,1,"cell differentiation;cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus","cytoplasm;cytoskeleton","catalytic activity;nucleotide binding","Pf00069, Pf03607, Pf07714, Pf14531","166614","ENSG00000170390.15","DCLK2","4","","","",0,0,0.762,-0.39,0.0131987198291317,0.21180749374056,84.5,93.2,122.3,"",6.35,5.23,90.7,"","",99,91.4,100.9,106.7,119.1,134.1,132.5,129.8,4.6,"","",79,69.2,80.1,77.3,85.8,134.1,108,103.6,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P56937","3-keto-steroid reductase OS=Homo sapiens OX=9606 GN=HSD17B7 PE=1 SV=1",0,18.451,11,4,8,4,341,38.2,8.1,22.39,4,"metabolic process","endoplasmic reticulum;membrane","catalytic activity","Pf00106, Pf03435, Pf08659, Pf13460","51478","ENSG00000132196.13","HSD17B7","1","Steroid hormone biosynthesis; Ovarian steroidogenesis; Steroid biosynthesis; Metabolic pathways","Cholesterol biosynthesis","Steroid Biosynthesis",9,0,1.205,0.27,0.0132385559046924,0.211906647396466,108.4,104.7,86.9,"",11.52,10.77,1369.8,"","",1368.9,1277.7,1411.4,1078.6,1170.3,1142.5,1054.1,914.1,69.5,"","",1092.4,967.1,1120.8,781.2,842.9,1142.5,859.1,729.4,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P09493-3","Isoform 3 of Tropomyosin alpha-1 chain OS=Homo sapiens OX=9606 GN=TPM1",0,86.088,46,23,48,4,284,32.9,4.78,131.11,23,"cell organization and biogenesis;cellular component movement;regulation of biological process;response to stimulus","cytoplasm;cytoskeleton;cytosol","protein binding;structural molecule activity","Pf00261, Pf12718","7168","ENSG00000140416.19","TPM1","15","","","Striated Muscle Contraction",1,3,0.854,-0.23,0.0133471426084462,0.212206085512063,94.9,94.5,110.7,"",20.31,4.91,2564.3,"","",2394.9,2724.3,2383.8,3581.5,3034.7,2759.6,2948.9,3092.1,130.1,"","",1911.1,2062,1893,2593.9,2185.7,2759.6,2403.4,2467.4,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q14114","Low-density lipoprotein receptor-related protein 8 OS=Homo sapiens OX=9606 GN=LRP8 PE=1 SV=4",0,45.155,14,12,14,1,963,105.6,5.05,38.5,12,"metabolic process;regulation of biological process;response to stimulus;transport","cell surface;extracellular;membrane","metal ion binding;protein binding;receptor activity;signal transducer activity","Pf00057, Pf00058, Pf06247, Pf07645, Pf08450, Pf12662, Pf14670","7804","ENSG00000157193.15","LRP8","1","","Signaling by GPCR; Retinoid metabolism and transport; Platelet sensitization by LDL","",10,6,1.22,0.29,0.0133266253145199,0.212206085512063,97.3,111.4,91.3,"",4.01,2.12,506.5,"","",577.8,582.9,602.9,546.9,491.9,469.2,479.1,472.1,25.7,"","",461.1,441.2,478.8,396.1,354.3,469.2,390.5,376.7,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q3KR37","Protein Aster-B OS=Homo sapiens OX=9606 GN=GRAMD1B PE=1 SV=1",0,20.246,9,6,7,5,738,85.3,6.21,17.42,6,"","membrane","","Pf02893","57476","ENSG00000023171.16","GRAMD1B","11","","","Ectoderm Differentiation",1,0,1.274,0.35,0.0134905584715879,0.214125771774245,113.2,104.7,82.2,"",16.22,5.26,163.6,"","",150.8,151.9,177.9,118.6,109.1,119.7,117.9,123.8,8.3,"","",120.3,115,141.3,85.9,78.6,119.7,96.1,98.8,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q9H7S9","Zinc finger protein 703 OS=Homo sapiens OX=9606 GN=ZNF703 PE=1 SV=1",0,6.506,4,2,2,2,590,58.2,8.79,5.64,2,"cell differentiation;cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus","cytoplasm;nucleus","metal ion binding;protein binding","Pf12402","80139","ENSG00000183779.6","ZNF703","8","","Generic Transcription Pathway","",3,0,0.728,-0.46,0.0136000232012716,0.215490340826071,"",126.4,173.6,"",11.56,9.33,"","","",39.6,38.3,32,42.4,57.1,50.2,49.1,59.3,"","","",31.6,29,25.4,30.7,41.1,50.2,40,47.3,"Not Found","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q6T4R5","Nance-Horan syndrome protein OS=Homo sapiens OX=9606 GN=NHS PE=1 SV=2",0,61.252,10,13,13,13,1651,179,6.86,47.65,13,"cell differentiation","cytoplasm;Golgi;membrane","","Pf15273","4810","","NHS","X","","","",0,0,0.827,-0.27,0.0138041243068698,0.218003595240934,105.8,87.9,106.3,"",2.66,5.12,904.7,"","",752.6,750.7,724,772.5,835.3,895,923.4,940,45.9,"","",600.6,568.2,574.9,559.5,601.6,895,752.6,750.1,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q8NEM2","SHC SH2 domain-binding protein 1 OS=Homo sapiens OX=9606 GN=SHCBP1 PE=1 SV=3",0,96.01,28,15,19,15,672,75.6,4.75,58.49,15,"regulation of biological process;response to stimulus","cytoplasm;cytoskeleton","protein binding","Pf05048, Pf12708, Pf13229","79801","ENSG00000171241.8","SHCBP1","16","","","",0,0,0.836,-0.26,0.0138329557265491,0.218276414171311,87.3,96.9,115.9,"",4.52,4.25,1052.5,"","",1132.5,1204.3,1233.7,1126.6,1435.5,1397.7,1395.9,1298.2,53.4,"","",903.7,911.5,979.7,815.9,1033.9,1397.7,1137.7,1035.9,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"Low","Master Protein","P48752","Packaging protein 1 OS=Human adenovirus F serotype 40 OX=28284 GN=IVa2 PE=3 SV=1",0.096,1.07,2,1,1,1,446,51.1,8.94,2.17,1,"metabolic process;regulation of biological process","","catalytic activity;DNA binding;nucleotide binding;RNA binding","Pf00910, Pf02456, Pf13401","2715937","","IVa2","","","","",0,0,1.294,0.37,0.0138622560864436,0.218373889041491,110.3,107,82.7,"",13.81,7.59,72.9,"","",89.1,68.8,72.8,66.3,55.4,59.2,49.2,54,3.7,"","",71.1,52.1,57.8,48,39.9,59.2,40.1,43.1,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P11117","Lysosomal acid phosphatase OS=Homo sapiens OX=9606 GN=ACP2 PE=1 SV=3",0,28.371,17,5,6,5,423,48.3,6.74,22.36,5,"cell organization and biogenesis;metabolic process","membrane;organelle lumen;vacuole","catalytic activity","Pf00328","53","ENSG00000134575.9","ACP2","11","Lysosome","","",1,0,0.814,-0.3,0.0138995725413635,0.218597107544775,91.5,93.5,114.9,"",6.47,5.99,441.5,"","",459.3,443.3,475.3,407.7,521.2,564.4,600,544.4,22.4,"","",366.5,335.5,377.4,295.3,375.4,564.4,489,434.4,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"Low","Master Protein","A0A1B0GUW7","Small integral membrane protein 27 OS=Homo sapiens OX=9606 GN=SMIM27 PE=3 SV=1",0.061,1.303,15,1,1,1,55,6.4,10.11,2.3,1,"","membrane","","","100129250","ENSG00000235453.8","LOC100129250; TOPORS-AS1; SMIM27","9","","","",0,0,1.38,0.46,0.0139825340467699,0.219065206202205,122.7,102.8,74.5,"",19.81,19.11,45.3,"","",39.1,37.5,38.4,24.6,36.1,29.8,25.4,23.8,2.3,"","",31.2,28.4,30.5,17.8,26,29.8,20.7,19,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q8TCD1","UPF0729 protein C18orf32 OS=Homo sapiens OX=9606 GN=C18orf32 PE=3 SV=1",0,11.105,24,3,3,3,76,8.7,9.13,8.21,3,"regulation of biological process;response to stimulus","","signal transducer activity","Pf14975","497661","ENSG00000177576.11","C18orf32","18","","","",0,0,1.274,0.35,0.0140004166287095,0.219088541245291,88.4,118.5,93,"",13.71,4.86,106.4,"","",181,146,136,139.5,114.1,119.6,107,109.9,5.4,"","",144.4,110.5,108,101,82.2,119.6,87.2,87.7,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q14353","Guanidinoacetate N-methyltransferase OS=Homo sapiens OX=9606 GN=GAMT PE=1 SV=1",0,10.68,13,3,3,3,236,26.3,6.14,9.27,3,"metabolic process;regulation of biological process","cytoplasm;cytosol;nucleus","catalytic activity","Pf13659","2593","ENSG00000130005.12","GAMT","19","Metabolic pathways; Glycine, serine and threonine metabolism; Arginine and proline metabolism","Creatine metabolism","Mecp2 and Associated Rett Syndrome; Urea cycle and metabolism of amino groups",9,0,1.273,0.35,0.0140183687383799,0.219187871465662,100.2,111.9,87.9,"",11.06,8.63,141.9,"","",154.9,177.4,135.5,162.2,144.1,123.9,119,125.1,7.2,"","",123.6,134.3,107.6,117.5,103.8,123.9,97,99.8,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P54289","Voltage-dependent calcium channel subunit alpha-2/delta-1 OS=Homo sapiens OX=9606 GN=CACNA2D1 PE=1 SV=3",0,63.392,17,16,18,16,1103,124.5,5.27,55.54,16,"cellular homeostasis;regulation of biological process;transport","endoplasmic reticulum;membrane","metal ion binding;transporter activity","Pf00092, Pf02743, Pf08399, Pf08473, Pf13519, Pf13768","781","ENSG00000153956.15","CACNA2D1","7","Arrhythmogenic right ventricular cardiomyopathy (ARVC); Cardiac muscle contraction; Dilated cardiomyopathy; Hypertrophic cardiomyopathy (HCM); MAPK signaling pathway; Oxytocin signaling pathway; Adrenergic signaling in cardiomyocytes","Phase 0 - rapid depolarisation; Phase 2 - plateau phase","Arrhythmogenic Right Ventricular Cardiomyopathy",12,0,1.214,0.28,0.0141054406451908,0.219459277517598,162.9,75.2,61.9,94.42,3.49,4.15,2067.6,10374.5,"",2101.5,2174,2210.9,2044.3,1704.5,1819.6,1700.2,1837.3,104.9,2.9,"",1677,1645.5,1755.7,1480.6,1227.6,1819.6,1385.7,1466.1,"High","High","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q9Y5Z7","Host cell factor 2 OS=Homo sapiens OX=9606 GN=HCFC2 PE=1 SV=1",0,16.53,7,5,6,4,792,86.7,8.48,15.04,5,"regulation of biological process","cytoplasm;cytosol;membrane;nucleus","protein binding","Pf00041, Pf01344, Pf13415, Pf13418, Pf13854","29915","ENSG00000111727.11","HCFC2","12","Herpes simplex infection","","",1,0,1.209,0.27,0.0142221668716314,0.221093241046398,87.1,116.5,96.4,"",5.64,6.07,530.2,"","",776.9,715.8,702.9,682.8,620.1,614.1,560.2,551.5,26.9,"","",620,541.8,558.2,494.5,446.6,614.1,456.6,440.1,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q92879-4","Isoform 4 of CUGBP Elav-like family member 1 OS=Homo sapiens OX=9606 GN=CELF1",0,97.643,29,14,32,1,512,55,8.38,105.83,14,"cell organization and biogenesis;metabolic process;regulation of biological process","cytoplasm;membrane;nucleus","protein binding;RNA binding;translation regulator activity","Pf00076, Pf13893, Pf14259","10658","ENSG00000149187.17","CELF1","11","","","Adipogenesis; mRNA Processing",2,14,0.857,-0.22,0.0142939053742945,0.221971854439004,155,66.9,78.1,89.94,3.18,2.34,2865.8,12878.7,"",2610.6,2527.4,2730.7,2632.8,3022.9,3086.5,3181.2,3035.2,145.4,3.6,"",2083.3,1913,2168.4,1906.8,2177.2,3086.5,2592.7,2422,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q9Y657","Spindlin-1 OS=Homo sapiens OX=9606 GN=SPIN1 PE=1 SV=3",0,52.577,48,13,16,13,262,29.6,6.96,41.2,13,"cell organization and biogenesis;development;metabolic process;regulation of biological process;response to stimulus","cytosol;membrane;nucleus","protein binding","Pf02513","10927","ENSG00000106723.16","SPIN1","9","","","",0,0,0.854,-0.23,0.0143021890540167,0.221971854439004,202.1,45.1,52.8,128.87,2.01,0.34,1283.1,"",27632.5,1293.4,1319.5,1355,1340,1546.2,1557.1,1556.9,1555.8,65.1,"",3.5,1032.1,998.7,1076,970.5,1113.6,1557.1,1268.9,1241.5,"High","Not Found","High","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q12873","Chromodomain-helicase-DNA-binding protein 3 OS=Homo sapiens OX=9606 GN=CHD3 PE=1 SV=3",0,182.837,24,41,54,33,2000,226.5,7.3,165.88,41,"cell organization and biogenesis;metabolic process;regulation of biological process","cytoplasm;cytoskeleton;nucleus","catalytic activity;DNA binding;metal ion binding;nucleotide binding;protein binding;RNA binding","Pf00176, Pf00271, Pf00385, Pf00628, Pf06461, Pf06465, Pf08073, Pf08074, Pf13831","1107","ENSG00000170004.16","CHD3","17","","SUMOylation of chromatin organization proteins; ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression; Regulation of TP53 Activity through Acetylation; Regulation of PTEN gene transcription; HDACs deacetylate histones; RNA Polymerase I Transcription Initiation","",25,0,0.854,-0.23,0.0153930805091249,0.233155176147836,100,92.2,107.9,"",11.39,5.4,4696.9,"","",4241.3,4114.1,4420.9,5253.9,5009.8,4642.6,5127,5277.7,238.3,"","",3384.6,3114,3510.6,3805.1,3608.2,4642.6,4178.6,4211.5,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","O60669","Monocarboxylate transporter 2 OS=Homo sapiens OX=9606 GN=SLC16A7 PE=1 SV=2",0,9.597,3,2,4,2,478,52.2,9.31,12.47,2,"transport","membrane","transporter activity","Pf00083, Pf07690","9194","ENSG00000118596.11","SLC16A7","12","","Proton-coupled monocarboxylate transport","",4,0,0.719,-0.48,0.0166081469704449,0.246035043119814,"",125.5,174.5,"",19.89,21.47,"","","",17.3,19.6,15.4,12,14.9,23.7,25.3,21.7,"","","",13.8,14.8,12.2,8.7,10.7,23.7,20.6,17.3,"Not Found","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q9HD67","Unconventional myosin-X OS=Homo sapiens OX=9606 GN=MYO10 PE=1 SV=3",1E-3,5.095,1,2,2,2,2058,237.2,6.21,2.58,2,"regulation of biological process;response to stimulus;transport","cytoplasm;cytoskeleton;cytosol;membrane","catalytic activity;motor activity;nucleotide binding;protein binding","Pf00063, Pf00169, Pf00373, Pf00769, Pf00784, Pf12325, Pf15409","4651","ENSG00000145555.14","MYO10","5","Fc gamma R-mediated phagocytosis","Netrin-1 signaling; Regulation of actin dynamics for phagocytic cup formation","",8,0,1.323,0.4,0.01762444280956,0.252572439899066,"",170.9,129.1,"",5.51,7.36,"","","",51.5,45.2,48.9,47.4,35,34.5,37.8,40.4,"","","",41.1,34.2,38.8,34.3,25.2,34.5,30.8,32.2,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","O75151","Lysine-specific demethylase PHF2 OS=Homo sapiens OX=9606 GN=PHF2 PE=1 SV=4",0,20.026,6,6,6,6,1096,120.7,9.17,19.18,6,"cell organization and biogenesis;metabolic process;regulation of biological process","chromosome;cytosol;nucleus","catalytic activity;metal ion binding;protein binding","Pf00628, Pf02373, Pf13621","5253","ENSG00000197724.10","PHF2","9","","HDMs demethylate histones","",3,0,0.822,-0.28,0.019479686169503,0.268563731656623,84.5,97.2,118.3,"",5.66,3.46,380.4,"","",430.1,445.8,472.2,413.7,514.1,531.8,533.5,559,19.3,"","",343.2,337.4,375,299.6,370.3,531.8,434.8,446.1,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q13636","Ras-related protein Rab-31 OS=Homo sapiens OX=9606 GN=RAB31 PE=1 SV=1",0,45.293,56,9,14,7,194,21.6,7.06,44.06,9,"cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus;transport","cytosol;endosome;Golgi;membrane","catalytic activity;nucleotide binding","Pf00009, Pf00025, Pf00071, Pf04670, Pf08477","11031","","RAB31","18","Endocytosis","Neutrophil degranulation; RAB GEFs exchange GTP for GDP on RABs; RAB geranylgeranylation","",11,1,1.197,0.26,0.0206476825681114,0.277690394281527,161.9,75.3,62.8,102.87,1.11,5.46,2032.1,12878.7,"",2389.8,2370.6,2332,2385.3,1942.9,2029.6,1878.7,2129.9,103.1,3.6,"",1907.1,1794.3,1851.8,1727.5,1399.3,2029.6,1531.2,1699.6,"High","High","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q9NZ43","Vesicle transport protein USE1 OS=Homo sapiens OX=9606 GN=USE1 PE=1 SV=2",0,42.217,25,7,9,7,259,29.4,9.07,29.21,7,"metabolic process;transport","endoplasmic reticulum;membrane;vacuole","protein binding","Pf09753","55850","ENSG00000053501.12","USE1","19","SNARE interactions in vesicular transport","COPI-dependent Golgi-to-ER retrograde traffic","",6,0,1.192,0.25,0.0224423264923659,0.292944480157434,96.9,110.5,92.7,"",1.95,4.73,855.4,"","",975.3,975.4,993.2,947.2,888.6,823.2,813.6,800.2,43.4,"","",778.3,738.3,788.7,686,640,823.2,663.1,638.5,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P20248","Cyclin-A2 OS=Homo sapiens OX=9606 GN=CCNA2 PE=1 SV=2",0,12.481,7,3,4,3,432,48.5,6.54,11.43,3,"cell division;cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus","cytoplasm;cytosol;nucleus","catalytic activity;protein binding","Pf00134, Pf02984","890","ENSG00000145386.9","CCNA2","4","Cell cycle; Hepatitis B; Epstein-Barr virus infection; Progesterone-mediated oocyte maturation; AMPK signaling pathway; Viral carcinogenesis","p53-Dependent G1 DNA Damage Response; Regulation of DNA replication; TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest; SCF(Skp2)-mediated degradation of p27/p21; G2 Phase; Regulation of APC/C activators between G1/S and early anaphase; Regulation of TP53 Activity through Phosphorylation; Ub-specific processing proteases; Regulation of TP53 Degradation; Phosphorylation of proteins involved in the G2/M transition by Cyclin A:Cdc2 complexes; Orc1 removal from chromatin; Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1; Processing of DNA double-strand break ends; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; DNA Damage/Telomere Stress Induced Senescence; Senescence-Associated Secretory Phenotype (SASP); Removal of licensing factors from origins","AMP-activated Protein Kinase (AMPK) Signaling; Cell Cycle; Retinoblastoma (RB) in Cancer",65,0,0.835,-0.26,0.0237288092573311,0.300596746648203,93.5,94,112.5,"",4,3.29,630.7,"","",647.6,614,669.7,621.2,754.2,724.1,783.8,764.4,32,"","",516.8,464.7,531.8,449.9,543.2,724.1,638.8,610,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q8WWK9","Cytoskeleton-associated protein 2 OS=Homo sapiens OX=9606 GN=CKAP2 PE=1 SV=1",0,52.791,19,13,16,2,683,76.9,9.41,51.46,13,"cell death;regulation of biological process","cytoplasm;cytoskeleton;cytosol","","Pf08542, Pf15297","26586","ENSG00000136108.14","CKAP2","13","","","",0,0,0.756,-0.4,0.0254050794995557,0.314244362532815,"",129.1,170.9,"",6.58,8.72,"","","",42.1,37.5,43.7,39.9,46.4,57,55,53.5,"","","",33.6,28.4,34.7,28.9,33.4,57,44.8,42.7,"Not Found","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q9UDY4","DnaJ homolog subfamily B member 4 OS=Homo sapiens OX=9606 GN=DNAJB4 PE=1 SV=1",0,41.784,28,8,14,7,337,37.8,8.5,45.7,8,"metabolic process;regulation of biological process;response to stimulus","cytoplasm;cytosol;membrane","enzyme regulator activity;protein binding","Pf00226, Pf01556","11080","ENSG00000162616.8","DNAJB4","1","","","",0,0,0.857,-0.22,0.0270997507194735,0.323561978578939,91.8,96.1,112.2,"",4.53,5.86,1141.2,"","",1225.3,1207.2,1104.1,1183.2,1469.7,1288.3,1434.8,1356.3,57.9,"","",977.8,913.7,876.8,856.9,1058.5,1288.3,1169.4,1082.3,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q15257","Serine/threonine-protein phosphatase 2A activator OS=Homo sapiens OX=9606 GN=PTPA PE=1 SV=3",0,69.228,40,13,20,13,358,40.6,5.94,63.68,13,"cell organization and biogenesis;metabolic process;regulation of biological process","cytoplasm;nucleus","catalytic activity;enzyme regulator activity;nucleotide binding;protein binding","Pf03095","5524","ENSG00000119383.19","PPP2R4; PTPA","9","Insulin resistance","","Interleukin-11 Signaling Pathway; Constitutive Androstane Receptor Pathway; ATM Signaling Network in Development and Disease; Wnt Signaling Pathway and Pluripotency; Glycogen Metabolism",6,0,0.864,-0.21,0.0285958861894318,0.332790571993831,102.6,91.5,105.9,"",4.45,3.55,2223.3,"","",1998.5,1965.4,1937.9,2139.1,2450.2,2297.5,2271.1,2291.4,112.8,"","",1594.8,1487.6,1538.9,1549.2,1764.7,2297.5,1851,1828.5,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q7Z6R9","Transcription factor AP-2-delta OS=Homo sapiens OX=9606 GN=TFAP2D PE=2 SV=1",1E-3,4.586,4,2,2,1,452,49.5,8.16,2.53,2,"metabolic process;regulation of biological process","nucleus","DNA binding","Pf03299","83741","ENSG00000008197.4","TFAP2D","6","","Negative regulation of activity of TFAP2 (AP-2) family transcription factors; Activation of the TFAP2 (AP-2) family of transcription factors","",6,0,0.799,-0.32,0.0303505449995656,0.344300957328405,111.9,83.5,104.6,"",5.02,2.82,279.9,"","",190.5,213.6,207.7,210.3,248.7,265,260,263,14.2,"","",152,161.7,164.9,152.3,179.1,265,211.9,209.9,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P29323-3","Isoform 3 of Ephrin type-B receptor 2 OS=Homo sapiens OX=9606 GN=EPHB2",0,22.118,7,6,6,6,987,110,5.71,17.1,6,"cell organization and biogenesis;cellular component movement;metabolic process;regulation of biological process;response to stimulus","cytosol;extracellular;membrane;nucleus","catalytic activity;nucleotide binding;protein binding;receptor activity;signal transducer activity","Pf00041, Pf00069, Pf00536, Pf01404, Pf07647, Pf07699, Pf07714, Pf14575","2048","ENSG00000133216.16","EPHB2","1","","","Regulation of Microtubule Cytoskeleton; NLR Proteins; Transcriptional activation by NRF2",3,0,1.221,0.29,0.0319206196157475,0.353202497540855,67.1,128,104.9,"",5.29,7.37,116.3,"","",222.4,221.4,232.2,204.2,186.6,195.1,164,177.1,5.9,"","",177.5,167.6,184.4,147.9,134.4,195.1,133.7,141.3,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q9BV86","N-terminal Xaa-Pro-Lys N-methyltransferase 1 OS=Homo sapiens OX=9606 GN=NTMT1 PE=1 SV=3",0,48.207,41,8,14,8,223,25.4,5.52,45.59,8,"cell organization and biogenesis;metabolic process","cytoplasm;cytosol;nucleus","catalytic activity;protein binding","Pf00891, Pf01209, Pf05891, Pf08241, Pf08242, Pf12847, Pf13489, Pf13649, Pf13847","28989","ENSG00000148335.14","NTMT1","9","","","",0,0,0.86,-0.22,0.0339389691598473,0.369688148495499,104.2,90.5,105.3,"",3.07,2.54,1375.7,"","",1228.6,1223.8,1158.3,1168.1,1434.8,1357.3,1410.2,1372.1,69.8,"","",980.4,926.3,919.8,846,1033.4,1357.3,1149.3,1094.9,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P53801","Pituitary tumor-transforming gene 1 protein-interacting protein OS=Homo sapiens OX=9606 GN=PTTG1IP PE=1 SV=1",0,13.67,20,3,4,3,180,20.3,8.79,11.62,3,"regulation of biological process;transport","cytoplasm;membrane;nucleus","protein binding","","754","ENSG00000183255.11","PTTG1IP","21","","","",0,0,0.846,-0.24,0.0353589456520034,0.374496767658355,84,99,117,"",5.65,2.76,546,"","",596.7,666,621.6,672.2,756.1,729,764.9,778.6,27.7,"","",476.2,504.1,493.6,486.8,544.6,729,623.4,621.3,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P20851","C4b-binding protein beta chain OS=Homo sapiens OX=9606 GN=C4BPB PE=1 SV=1",0,16.616,20,5,5,5,252,28.3,5.14,16.89,5,"coagulation;defense response;metabolic process;regulation of biological process;response to stimulus","extracellular;membrane","protein binding","Pf00084","725","ENSG00000123843.12","C4BPB","1","Complement and coagulation cascades; Pertussis","Regulation of Complement cascade","",6,0,0.848,-0.24,0.038422073883398,0.391872691183653,88.5,97.1,114.5,"",9.23,2.76,676,"","",689.7,777.2,708,842.1,831.5,885.4,875.1,874.3,34.3,"","",550.4,588.3,562.2,609.9,598.9,885.4,713.2,697.7,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","O00458","Interferon-related developmental regulator 1 OS=Homo sapiens OX=9606 GN=IFRD1 PE=1 SV=4",0,10.644,11,3,3,3,451,50.2,7.18,5.83,3,"cell differentiation;development;regulation of biological process","cytoplasm;nucleus","","Pf04836, Pf05004","3475","ENSG00000006652.13","IFRD1","7","","","Hypertrophy Model",1,0,0.765,-0.39,0.0399793133135429,0.398906111920865,"",130,170,"",7.24,10.8,"","","",37,41.7,37.8,42.8,57.5,45.8,48.5,55.6,"","","",29.5,31.6,30,31,41.4,45.8,39.5,44.4,"Not Found","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q8WVC0","RNA polymerase-associated protein LEO1 OS=Homo sapiens OX=9606 GN=LEO1 PE=1 SV=1",0,38.876,15,10,13,10,666,75.4,4.51,28.14,10,"cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus","nucleus","protein binding","Pf04004, Pf04147","123169","ENSG00000166477.12","LEO1","15","","E3 ubiquitin ligases ubiquitinate target proteins; Formation of the beta-catenin:TCF transactivating complex; Formation of RNA Pol II elongation complex ; RNA Polymerase II Pre-transcription Events","Endoderm Differentiation",14,0,0.872,-0.2,0.0421152600528605,0.412162192683124,172.2,59.5,68.3,108.07,6.94,3.63,1817.2,13594.2,"",1695.7,1686,1741.7,1948.4,1956.2,1890.3,1987.7,2063.1,92.2,3.8,"",1353.2,1276.1,1383.1,1411.1,1408.9,1890.3,1620,1646.3,"High","High","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q6YHK3","CD109 antigen OS=Homo sapiens OX=9606 GN=CD109 PE=1 SV=2",0,208.355,25,33,47,33,1445,161.6,5.85,175.86,33,"metabolic process;regulation of biological process;transport","cell surface;extracellular;membrane","enzyme regulator activity;protein binding","Pf00207, Pf01835, Pf07677, Pf07678, Pf07703, Pf10569, Pf11974, Pf13249","135228","ENSG00000156535.13","CD109","6","","Platelet degranulation ; Post-translational modification: synthesis of GPI-anchored proteins","",7,0,1.134,0.18,0.0449145627477945,0.43040778073786,126.3,92.3,81.4,41.71,2.45,6.83,5453.7,10016.8,"",5219.5,5372.6,5430.7,5536.6,4548.1,4881.8,4644,5290.1,276.7,2.8,"",4165.2,4066.5,4312.5,4009.8,3275.7,4881.8,3784.9,4221.4,"High","High","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q8NFY4","Semaphorin-6D OS=Homo sapiens OX=9606 GN=SEMA6D PE=1 SV=1",0,30.792,10,9,9,9,1073,119.8,8.51,27.9,9,"cell differentiation;development;regulation of biological process","cytoplasm;Golgi;membrane","protein binding","Pf01403, Pf01437, Pf06295","80031","ENSG00000137872.16","SEMA6D","15","Axon guidance","Other semaphorin interactions","",5,0,0.847,-0.24,0.0466901662277159,0.436972341707139,96.9,93.2,110,"",5.86,5.68,512.5,"","",489.7,455.8,496,526.1,577,527.3,586.5,603,26,"","",390.8,345,393.9,381,415.6,527.3,478,481.2,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q9UKT7","F-box/LRR-repeat protein 3 OS=Homo sapiens OX=9606 GN=FBXL3 PE=1 SV=1",0,5.906,3,1,1,1,428,48.7,6.89,3.7,1,"metabolic process;regulation of biological process;response to stimulus","cytoplasm;cytosol;nucleus","catalytic activity;protein binding","Pf00646, Pf12937","26224","ENSG00000005812.10","FBXL3","13","Circadian rhythm","Association of TriC/CCT with target proteins during biosynthesis; Antigen processing: Ubiquitination & Proteasome degradation; Neddylation; Circadian Clock","",12,0,0.801,-0.32,0.0499403896157284,0.457677864658845,98.5,89.6,111.9,"",12.97,9.97,84.8,"","",68.4,79.1,75.1,92.6,103.6,81.3,97.4,95.1,4.3,"","",54.6,59.9,59.6,67.1,74.6,81.3,79.4,75.9,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q13905","Rap guanine nucleotide exchange factor 1 OS=Homo sapiens OX=9606 GN=RAPGEF1 PE=1 SV=3",0,19.338,7,6,6,6,1077,120.5,5.92,16.65,6,"regulation of biological process;response to stimulus","cytoplasm;cytosol;endosome;membrane","protein binding","Pf00617, Pf00618","2889","ENSG00000107263.18","RAPGEF1","9","Focal adhesion; Insulin signaling pathway; Rap1 signaling pathway; Renal cell carcinoma; Neurotrophin signaling pathway","Frs2-mediated activation; Regulation of signaling by CBL; MET activates RAP1 and RAC1; Downstream signal transduction","Integrin-mediated Cell Adhesion; B Cell Receptor Signaling Pathway; IL-3 Signaling Pathway; Focal Adhesion; Signaling of Hepatocyte Growth Factor Receptor; VEGFA-VEGFR2 Signaling Pathway; Angiopoietin Like Protein 8 Regulatory Pathway; Insulin Signaling; Interferon type I signaling pathways",31,0,0.816,-0.29,0.052925967812059,0.473775203807664,81.4,98.2,120.4,"",3.17,6.81,159.6,"","",191.9,192.5,204.8,192.9,221.3,230.4,242,258.9,8.1,"","",153.1,145.7,162.6,139.7,159.4,230.4,197.2,206.6,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P79522","Proline-rich protein 3 OS=Homo sapiens OX=9606 GN=PRR3 PE=1 SV=2",0,15.296,19,2,4,2,188,20.6,9.83,9.93,2,"","","metal ion binding;protein binding;RNA binding","Pf00642","80742","ENSG00000228186.10; ENSG00000206491.12; ENSG00000233564.10; ENSG00000223887.10; ENSG00000204576.11; ENSG00000223766.10; ENSG00000229202.10","PRR3","6; CHR_HSCHR6_MHC_COX_CTG1; CHR_HSCHR6_MHC_QBL_CTG1; CHR_HSCHR6_MHC_MCF_CTG1; CHR_HSCHR6_MHC_DBB_CTG1; CHR_HSCHR6_MHC_MANN_CTG1; CHR_HSCHR6_MHC_SSTO_CTG1","","","",0,0,1.187,0.25,0.0559411522127249,0.488270093804967,100.6,108.2,91.2,"",11.26,3.63,285.8,"","",309.1,305.9,310.2,242.7,257.3,241.7,261.5,260.9,14.5,"","",246.7,231.5,246.3,175.8,185.3,241.7,213.1,208.2,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q9NV66","S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase TYW1 OS=Homo sapiens OX=9606 GN=TYW1 PE=2 SV=2",0,23.712,9,6,6,6,732,83.6,6.87,20.03,6,"metabolic process","","catalytic activity;metal ion binding;nucleotide binding","Pf00258, Pf04055, Pf08608","55253","ENSG00000198874.12","TYW1","7","","Synthesis of wybutosine at G37 of tRNA(Phe)","",4,0,1.157,0.21,0.0577162708077479,0.498293461942292,211.9,47.3,40.8,129.52,5.68,6.66,565.7,12878.7,"",594,613.7,610,541.1,555,529.3,511.2,473.1,28.7,3.6,"",474,464.5,484.4,391.9,399.7,529.3,416.6,377.5,"High","High","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q9NUQ8","ATP-binding cassette sub-family F member 3 OS=Homo sapiens OX=9606 GN=ABCF3 PE=1 SV=2",0,107.683,37,23,32,23,709,79.7,6.34,93.35,23,"defense response;response to stimulus","membrane","catalytic activity;nucleotide binding;protein binding","Pf00005, Pf02463, Pf12848, Pf13304","55324","ENSG00000161204.11","ABCF3","3","","","",0,0,1.134,0.18,0.060196762268333,0.508850593721785,132,89.3,78.7,55.97,5.49,5.78,4026.7,9301.3,"",4165,4116.7,4169.1,3709.4,3542.2,3442.7,3910.3,3765,204.3,2.6,"",3323.7,3115.9,3310.7,2686.5,2551.2,3442.7,3186.9,3004.4,"High","High","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P18031","Tyrosine-protein phosphatase non-receptor type 1 OS=Homo sapiens OX=9606 GN=PTPN1 PE=1 SV=1",0,97.421,47,23,32,23,435,49.9,6.27,99.71,23,"cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus","cytoplasm;cytosol;endoplasmic reticulum;endosome;membrane","catalytic activity;metal ion binding;protein binding;RNA binding","Pf00102, Pf00782","5770","ENSG00000196396.9","PTPN1","20","Insulin signaling pathway; Insulin resistance; Adherens junction","Regulation of IFNA signaling; Negative regulation of MET activity; Regulation of IFNG signaling; PTK6 Down-Regulation; Integrin alphaIIb beta3 signaling; Growth hormone receptor signaling","Leptin signaling pathway; Prolactin Signaling Pathway; VEGFA-VEGFR2 Signaling Pathway; Angiopoietin Like Protein 8 Regulatory Pathway; Insulin Signaling",28,0,1.135,0.18,0.0618611407136158,0.516777189650055,109.8,101.1,89.1,"",11.38,6.45,4844.7,"","",4365,4566.3,4838.7,3676.5,3827.1,4228.7,4041.9,3645.2,245.8,"","",3483.3,3456.2,3842.4,2662.7,2756.4,4228.7,3294.2,2908.8,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q8WVM7","Cohesin subunit SA-1 OS=Homo sapiens OX=9606 GN=STAG1 PE=1 SV=3",0,99.407,19,23,31,16,1258,144.3,5.59,90.93,23,"cell division;cell organization and biogenesis;metabolic process;regulation of biological process","chromosome;cytosol;nucleus","protein binding","Pf08514","10274","ENSG00000118007.12","STAG1","3","Cell cycle","Meiotic synapsis; Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; Cohesin Loading onto Chromatin; Establishment of Sister Chromatid Cohesion; SUMOylation of DNA damage response and repair proteins","",21,0,0.884,-0.18,0.0642937163066732,0.527727520152418,88.7,99.2,112.1,"",8.01,8.81,1308.7,"","",1381.9,1406.1,1522.6,1641.2,1592,1452.2,1719.5,1775.6,66.4,"","",1102.8,1064.3,1209.1,1188.6,1146.6,1452.2,1401.4,1416.9,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q14232","Translation initiation factor eIF-2B subunit alpha OS=Homo sapiens OX=9606 GN=EIF2B1 PE=1 SV=1",0,72.37,42,14,20,14,305,33.7,7.33,59.73,14,"metabolic process;response to stimulus","cytoplasm;cytosol;membrane","protein binding;RNA binding","Pf01008","1967","ENSG00000111361.12","EIF2B1","12","RNA transport","Recycling of eIF2:GDP","Translation Factors",7,0,1.128,0.17,0.0663488048816248,0.536323700117039,155.4,76.7,67.9,81.44,4.5,2.71,3851.3,14309.7,"",3640.1,3685.6,3726.2,3367.4,3283.5,3259.8,3232,3089.6,195.4,4,"",2904.8,2789.6,2959,2438.8,2364.9,3259.8,2634.1,2465.4,"High","High","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q92844","TRAF family member-associated NF-kappa-B activator OS=Homo sapiens OX=9606 GN=TANK PE=1 SV=2",0,12.687,9,3,3,3,425,47.8,5.68,10.66,3,"metabolic process;regulation of biological process;response to stimulus","cytoplasm;cytosol","catalytic activity;enzyme regulator activity;metal ion binding;protein binding","Pf12845","10010","ENSG00000136560.13","TANK","2","NOD-like receptor signaling pathway; RIG-I-like receptor signaling pathway","TICAM1-dependent activation of IRF3/IRF7; Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon; TRAF6 mediated IRF7 activation; Activated TLR4 signalling","TNF alpha Signaling Pathway; Structural Pathway of Interleukin 1 (IL-1); RIG-I-like Receptor Signaling",17,0,1.195,0.26,0.0686819019164551,0.545756736810266,52.3,134.9,112.9,"",2.82,7.95,63.1,"","",159.9,156.8,166.2,165.7,126.9,139.6,133,152.5,3.2,"","",127.6,118.7,132,120,91.4,139.6,108.4,121.7,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","O14975","Very long-chain acyl-CoA synthetase OS=Homo sapiens OX=9606 GN=SLC27A2 PE=1 SV=2",0,157.958,43,27,50,27,620,70.3,8.51,154.78,27,"metabolic process;transport","endoplasmic reticulum;membrane;mitochondrion;organelle lumen","catalytic activity;nucleotide binding;protein binding;transporter activity","Pf00501, Pf13193","11001","ENSG00000140284.10","SLC27A2","15","PPAR signaling pathway; Insulin resistance; Peroxisome","Neutrophil degranulation; Synthesis of bile acids and bile salts via 24-hydroxycholesterol; Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol; Alpha-oxidation of phytanate","PPAR signaling pathway",17,0,0.882,-0.18,0.0709252960662827,0.555931204122196,96.9,95.2,107.9,"",5.3,3.45,4227.8,"","",4028.3,4313.2,4284.2,3854.4,4702,5019,4713.6,4662.4,214.5,"","",3214.6,3264.7,3402.1,2791.5,3386.5,5019,3841.6,3720.5,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q8NBT0","POC1 centriolar protein homolog A OS=Homo sapiens OX=9606 GN=POC1A PE=1 SV=2",0,9.257,5,2,2,2,407,45,7.59,7.72,2,"cell organization and biogenesis;regulation of biological process","cytoplasm;cytoskeleton","protein binding","Pf00400, Pf06962, Pf08662","25886","ENSG00000164087.7","POC1A","3","","","",0,0,0.834,-0.26,0.0735288993841174,0.565017840344675,59.1,109.5,131.3,"",7.36,0.9,102.5,"","",181.6,198.4,208.7,178.9,224.5,228.4,229.1,226.7,5.2,"","",144.9,150.2,165.7,129.6,161.7,228.4,186.7,180.9,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q8NEM0-3","Isoform 3 of Microcephalin OS=Homo sapiens OX=9606 GN=MCPH1",0,12.606,5,3,3,3,610,67.9,8,9.01,3,"cell organization and biogenesis;regulation of biological process","cytoplasm","protein binding","Pf00533, Pf12258, Pf12738","79648","ENSG00000147316.12","MCPH1","8","","","",0,0,1.18,0.24,0.0756974464795523,0.573468417290445,94.7,111.1,94.1,"",5.58,3.74,210.9,"","",258.8,226.7,251,244,213,195.7,208.6,210.7,10.7,"","",206.5,171.6,199.3,176.7,153.4,195.7,170,168.1,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","O14523","Phospholipid transfer protein C2CD2L OS=Homo sapiens OX=9606 GN=C2CD2L PE=1 SV=3",0,10.787,6,3,3,3,706,76.1,7.69,9.88,3,"regulation of biological process;transport","endoplasmic reticulum;membrane","transporter activity","","9854","","C2CD2L","11","","","",0,0,1.175,0.23,0.0770837127176598,0.578219684595377,118.3,98.1,83.5,"",4.05,14.9,297.6,"","",252.6,232.1,241.2,252.5,195.2,200.1,220.6,267.3,15.1,"","",201.6,175.7,191.5,182.9,140.6,200.1,179.8,213.3,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q86YQ8","Copine-8 OS=Homo sapiens OX=9606 GN=CPNE8 PE=1 SV=2",0,53.266,26,12,17,12,564,63.1,5.96,44.04,12,"","","protein binding","Pf00168, Pf07002, Pf10138","144402","ENSG00000139117.13","CPNE8","12","","","",0,0,0.884,-0.18,0.0807831889038546,0.590126918452421,95.4,96,108.6,"",2.86,2.08,1951.3,"","",1961.3,1966.7,1894.4,2031.8,2259.6,2219.4,2222.2,2149.2,99,"","",1565.1,1488.6,1504.3,1471.5,1627.4,2219.4,1811.1,1715,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P26718","NKG2-D type II integral membrane protein OS=Homo sapiens OX=9606 GN=KLRK1 PE=1 SV=1",0,8.849,13,3,4,3,216,25.3,8.21,10.9,3,"cell differentiation;defense response;regulation of biological process;response to stimulus","cell surface;membrane","protein binding;receptor activity;signal transducer activity","Pf00059","22914; 100528032","","KLRK1; KLRC4-KLRK1","12","Natural killer cell mediated cytotoxicity; Malaria","DAP12 signaling; Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell","",8,0,0.881,-0.18,0.0813847994154944,0.591915527545561,100.3,93.5,106.2,"",4.18,1.73,1192.4,"","",1097.7,1186.3,1078.7,1126.6,1221.4,1268.8,1262.8,1261.6,60.5,"","",876,897.9,856.6,815.9,879.7,1268.8,1029.2,1006.7,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P30041","Peroxiredoxin-6 OS=Homo sapiens OX=9606 GN=PRDX6 PE=1 SV=3",0,153.478,62,21,105,21,224,25,6.38,307.8,21,"cellular homeostasis;metabolic process;regulation of biological process;response to stimulus;transport","cytoplasm;cytosol;extracellular;membrane;nucleus;organelle lumen;vacuole","antioxidant activity;catalytic activity;protein binding","Pf00578, Pf08534, Pf10417","9588","ENSG00000117592.8","PRDX6","1","Metabolic pathways","Neutrophil degranulation; Detoxification of Reactive Oxygen Species","NRF2 pathway",8,0,1.111,0.15,0.0847323064099941,0.601436979884242,102.5,104,93.6,69.25,5.78,3.61,11171.5,8943.5,30001,11675.9,11538.9,11126.4,10245.8,9751.4,9941.9,10460.6,10474,566.8,2.5,3.8,9317.4,8733.8,8835.4,7420.4,7023.2,9941.9,8525.5,8358,"High","High","High","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q6ZN18","Zinc finger protein AEBP2 OS=Homo sapiens OX=9606 GN=AEBP2 PE=1 SV=2",0,63.939,23,9,10,9,517,54.4,5.21,38.6,9,"cell organization and biogenesis;metabolic process;regulation of biological process","nucleus","DNA binding;metal ion binding;protein binding","Pf13465","121536","ENSG00000139154.14","AEBP2","12","","PRC2 methylates histones and DNA; PKMTs methylate histone lysines","Histone Modifications; Mesodermal Commitment Pathway; Interactome of polycomb repressive complex 2 (PRC2)",9,0,0.85,-0.24,0.0848611578105463,0.601899192161321,108,88.2,103.8,"",3.77,3.55,350.8,"","",276.9,301.2,281.6,291.9,335.3,322.3,351.3,339.6,17.8,"","",221,228,223.6,211.4,241.5,322.3,286.3,271,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q15910","Histone-lysine N-methyltransferase EZH2 OS=Homo sapiens OX=9606 GN=EZH2 PE=1 SV=2",0,90.426,26,16,19,13,746,85.3,7.02,67.15,16,"cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus","cytoplasm;nucleus","catalytic activity;DNA binding;protein binding;RNA binding","Pf00856, Pf11616","2146","ENSG00000106462.10","EZH2","7","Lysine degradation; MicroRNAs in cancer","Regulation of PTEN gene transcription; Transcriptional Regulation by E2F6; PRC2 methylates histones and DNA; PKMTs methylate histone lysines; Activation of anterior HOX genes in hindbrain development during early embryogenesis; Oxidative Stress Induced Senescence","miRs in Muscle Cell Differentiation; Histone Modifications; Endoderm Differentiation; Interactome of polycomb repressive complex 2 (PRC2); Mecp2 and Associated Rett Syndrome",28,2,0.89,-0.17,0.08705957164996,0.607904321376874,98,95.1,106.9,"",3.66,4.56,2004.5,"","",1930.4,1959.3,1973.4,1818.5,2021,2175.5,2251.5,2195.1,101.7,"","",1540.5,1483,1567.1,1317,1455.6,2175.5,1835,1751.6,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q16222","UDP-N-acetylhexosamine pyrophosphorylase OS=Homo sapiens OX=9606 GN=UAP1 PE=1 SV=3",0,99.113,38,16,23,15,522,58.7,6.33,63.87,16,"metabolic process","cytoplasm;cytosol;membrane","catalytic activity;protein binding","Pf01704","6675","ENSG00000117143.13","UAP1","1","Metabolic pathways; Amino sugar and nucleotide sugar metabolism","Synthesis of UDP-N-acetyl-glucosamine","",8,1,1.139,0.19,0.0905238376043187,0.623068132427929,225.9,39.4,34.6,76.08,1.11,2.18,2885.5,15382.9,24474.5,2720.5,2698.6,2673.5,2651.9,2302.1,2361.3,2427.7,2355.8,146.4,4.3,3.1,2171,2042.6,2123,1920.6,1658,2361.3,1978.6,1879.9,"High","High","High","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q9H204","Mediator of RNA polymerase II transcription subunit 28 OS=Homo sapiens OX=9606 GN=MED28 PE=1 SV=1",0.003,3.712,7,1,1,1,178,19.5,5.58,2.19,1,"metabolic process;regulation of biological process","cytoplasm;cytoskeleton;membrane;nucleus","protein binding","Pf11594","80306","ENSG00000118579.12","MED28","4","","Transcriptional regulation of white adipocyte differentiation; PPARA activates gene expression","",6,0,0.828,-0.27,0.0923413853150459,0.626713649238443,81,99.2,119.8,"",14.95,12.03,53.2,"","",63.7,66.7,66.7,47.6,62.9,78.2,84,79.2,2.7,"","",50.8,50.5,53,34.5,45.3,78.2,68.5,63.2,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q9NXR1-1","Isoform 2 of Nuclear distribution protein nudE homolog 1 OS=Homo sapiens OX=9606 GN=NDE1",0,35.851,29,10,11,8,346,38.8,5.27,33.01,10,"cell differentiation;cell division;cell organization and biogenesis;cell proliferation;cellular component movement;development;metabolic process;regulation of biological process;transport","chromosome;cytoplasm;cytoskeleton;cytosol;membrane","protein binding;transporter activity","Pf01496, Pf04111, Pf04156, Pf04880, Pf05557, Pf05622, Pf09726, Pf12128, Pf13851, Pf13949","54820","","NDE1","16","","Regulation of PLK1 Activity at G2/M Transition; AURKA Activation by TPX2; Anchoring of the basal body to the plasma membrane; Recruitment of NuMA to mitotic centrosomes; Recruitment of mitotic centrosome proteins and complexes; Loss of Nlp from mitotic centrosomes; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal; Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins","",28,2,0.881,-0.18,0.0959143438393288,0.63700074769242,93.1,96.9,110,"",2.31,2,936.2,"","",981.3,1004.6,967.3,951.5,1098.4,1123.8,1113.5,1073,47.5,"","",783.1,760.4,768.1,689.1,791.1,1123.8,907.5,856.2,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q9UN79","Transcription factor SOX-13 OS=Homo sapiens OX=9606 GN=SOX13 PE=1 SV=3",0,26.849,11,6,9,6,622,69.2,6.71,25.1,6,"metabolic process;regulation of biological process","nucleus","DNA binding;protein binding","Pf00505, Pf03154, Pf09011","9580","ENSG00000143842.14","SOX13","1","","Deactivation of the beta-catenin transactivating complex","",4,0,0.87,-0.2,0.0980287687767136,0.643805153500969,79.1,102.7,118.1,"",2.9,3.43,360.7,"","",460.9,486.2,456.6,475.7,526.8,550,525.8,563.8,18.3,"","",367.8,368,362.6,344.5,379.4,550,428.5,449.9,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P82914","28S ribosomal protein S15, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS15 PE=1 SV=1",0,33.876,31,10,13,10,257,29.8,10.48,31.53,10,"cell organization and biogenesis;metabolic process","membrane;mitochondrion;nucleus;ribosome","RNA binding;structural molecule activity","Pf00312","64960","ENSG00000116898.11","MRPS15","1","Ribosome","Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination","",7,0,1.141,0.19,0.101734604828832,0.65829503802911,97.7,107.8,94.5,"",5.47,4.38,2327.7,"","",2627.8,2556.5,2584.1,2320.1,2202.4,2305.2,2178,2393.9,118.1,"","",2097,1935,2052,1680.3,1586.2,2305.2,1775.1,1910.3,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P08603","Complement factor H OS=Homo sapiens OX=9606 GN=CFH PE=1 SV=4",0,218.507,35,35,48,35,1231,139,6.61,163.92,35,"defense response;metabolic process;regulation of biological process;response to stimulus","extracellular","protein binding","Pf00084","3075","","CFH","1","Complement and coagulation cascades; Staphylococcus aureus infection","Regulation of Complement cascade","Complement and Coagulation Cascades",7,0,1.105,0.14,0.105057699132284,0.670608253197222,156.5,75.3,68.2,84.74,1.39,5.11,6529.9,"",26053.5,6213.1,6208.5,6346,6376.1,5433.8,5836.6,5535.9,6077,331.3,"",3.3,4958.1,4699.2,5039.3,4617.8,3913.6,5836.6,4511.8,4849.3,"High","Not Found","High","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q9HCE0","Ectopic P granules protein 5 homolog OS=Homo sapiens OX=9606 GN=EPG5 PE=1 SV=2",0,19.483,2,4,4,4,2579,292.3,6.43,8.55,4,"cell organization and biogenesis;metabolic process;transport","cytoplasm","","","57724","ENSG00000152223.12","EPG5","18","","","",0,0,0.857,-0.22,0.108022630102779,0.680564188586153,108.7,88.3,103,"",26.61,10.98,299.6,"","",234,237.2,249.6,387,277.3,232.7,301.7,290.5,15.2,"","",186.7,179.5,198.2,280.3,199.7,232.7,245.9,231.8,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q16822","Phosphoenolpyruvate carboxykinase [GTP], mitochondrial OS=Homo sapiens OX=9606 GN=PCK2 PE=1 SV=4",0,108.225,41,26,39,26,640,70.7,7.62,99.18,26,"","","","","","","","","","","",0,0,1.113,0.15,0.110149828642412,0.687317463957015,106.6,101.9,91.5,"",6.5,4.14,4415,"","",4359.4,4083.5,4650.7,4054.9,3772.1,3807,3731,4082.8,224,"","",3478.8,3090.8,3693.1,2936.7,2716.8,3807,3040.8,3258,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q7Z7C8","Transcription initiation factor TFIID subunit 8 OS=Homo sapiens OX=9606 GN=TAF8 PE=1 SV=1",0,33.392,28,7,8,7,310,34.2,6.46,25.51,7,"cell differentiation;cell proliferation;development;metabolic process;regulation of biological process","cytoplasm;nucleus","protein binding","Pf07524, Pf10406","129685","ENSG00000137413.15","TAF8","6","Basal transcription factors","RNA polymerase II transcribes snRNA genes","",4,0,0.886,-0.17,0.112549609267906,0.693132383388398,82.4,102.2,115.4,"",6.91,2.78,778.5,"","",970.5,961.3,947.1,1095.6,1090.5,1089.4,1047.7,1121.3,39.5,"","",774.5,727.6,752.1,793.5,785.4,1089.4,853.9,894.8,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q6NUM9","All-trans-retinol 13,14-reductase OS=Homo sapiens OX=9606 GN=RETSAT PE=1 SV=2",0,31.752,11,6,7,6,610,66.8,8.28,22.63,6,"metabolic process","endoplasmic reticulum;membrane","catalytic activity","Pf13450","54884","ENSG00000042445.13","RETSAT","2","Retinol metabolism","Signaling by GPCR; Retinoid metabolism and transport","Vitamin A and Carotenoid Metabolism",9,0,1.133,0.18,0.114440113314528,0.69732512655264,201.2,52.5,46.3,118.23,9.38,2.43,1054.5,11805.5,"",919.2,949.5,921.3,765.5,808.9,838.4,814.8,790.5,53.5,3.3,"",733.5,718.7,731.6,554.4,582.6,838.4,664.1,630.8,"High","High","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q8WVD3","E3 ubiquitin-protein ligase RNF138 OS=Homo sapiens OX=9606 GN=RNF138 PE=1 SV=1",1E-3,4.512,4,1,2,1,245,28.2,6.93,7.06,1,"metabolic process;regulation of biological process;response to stimulus","chromosome;nucleus","catalytic activity;DNA binding;metal ion binding;protein binding","Pf00097, Pf02891, Pf05605, Pf13445, Pf13639, Pf13923, Pf14634, Pf14835","51444","ENSG00000134758.13","RNF138","18","","Antigen processing: Ubiquitination & Proteasome degradation","",4,0,1.223,0.29,0.117345005482103,0.704070032892615,"",165,135,"",18.24,12.72,"","","",25.6,39.5,37.3,37.8,30.3,24.6,31.2,33.6,"","","",20.4,29.9,29.6,27.4,21.8,24.6,25.4,26.8,"Not Found","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q8N4J0","Carnosine N-methyltransferase OS=Homo sapiens OX=9606 GN=CARNMT1 PE=1 SV=1",0,16.125,11,5,5,5,409,47.2,6.32,15.15,5,"metabolic process","cytoplasm;cytosol;nucleus","catalytic activity","Pf07942","138199","ENSG00000156017.12","C9orf41; CARNMT1","9","Histidine metabolism","Histidine catabolism","",5,0,1.129,0.18,0.119778729054937,0.708543888001767,103.2,104.4,92.4,"",3.67,1.52,950,"","",960.9,978.5,961.7,899.3,862.5,849.2,831.8,853.4,48.2,"","",766.8,740.6,763.7,651.3,621.2,849.2,677.9,681,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P18615","Negative elongation factor E OS=Homo sapiens OX=9606 GN=NELFE PE=1 SV=3",0,145.551,46,20,32,20,380,43.2,9.33,119.66,20,"metabolic process;regulation of biological process","membrane;nucleus","protein binding;RNA binding","Pf00076, Pf13893, Pf14259, Pf14605","7936","ENSG00000204356.13; ENSG00000206268.11; ENSG00000233801.9; ENSG00000206357.11; ENSG00000231044.10; ENSG00000229363.9","NELFE; RDBP","6; CHR_HSCHR6_MHC_DBB_CTG1; CHR_HSCHR6_MHC_SSTO_CTG1; CHR_HSCHR6_MHC_QBL_CTG1; CHR_HSCHR6_MHC_COX_CTG1; CHR_HSCHR6_MHC_MCF_CTG1","","HIV elongation arrest and recovery; Formation of the HIV-1 Early Elongation Complex; Abortive elongation of HIV-1 transcript in the absence of Tat; TP53 Regulates Transcription of DNA Repair Genes; Tat-mediated HIV elongation arrest and recovery; Formation of RNA Pol II elongation complex ; Formation of HIV elongation complex in the absence of HIV Tat; RNA Polymerase II Pre-transcription Events; Pausing and recovery of HIV elongation; Pausing and recovery of Tat-mediated HIV elongation; Formation of HIV-1 elongation complex containing HIV-1 Tat; Formation of the Early Elongation Complex","Initiation of transcription and translation elongation at the HIV-1 LTR",26,0,0.901,-0.15,0.123169182366764,0.71418038930728,94.2,97.6,108.3,"",1.41,0.94,2976.2,"","",3149.6,3049,3098.2,3069.3,3371.6,3444.6,3410.5,3432.3,151,"","",2513.4,2307.8,2460.3,2222.9,2428.3,3444.6,2779.6,2738.9,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q92636","Protein FAN OS=Homo sapiens OX=9606 GN=NSMAF PE=1 SV=2",0,20.794,7,7,8,7,917,104.3,6.23,20.48,7,"metabolic process;regulation of biological process;response to stimulus","cytoplasm;cytosol","enzyme regulator activity;protein binding;signal transducer activity","Pf00400, Pf02138, Pf02893, Pf14844","8439","ENSG00000035681.7","NSMAF","8","Sphingolipid signaling pathway","TNFR1-mediated ceramide production","TNF alpha Signaling Pathway",6,0,1.151,0.2,0.122616160033493,0.71418038930728,86.2,114.4,99.4,"",4.32,7.02,191.2,"","",237.2,259.2,248.3,260.4,248.5,214.2,215.7,225.1,9.7,"","",189.3,196.2,197.2,188.6,179,214.2,175.8,179.6,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q13614","Myotubularin-related protein 2 OS=Homo sapiens OX=9606 GN=MTMR2 PE=1 SV=4",0,44.406,21,11,11,11,643,73.3,7.4,34.28,11,"cell organization and biogenesis;metabolic process;regulation of biological process","cytoplasm;cytosol;endosome;membrane;nucleus","catalytic activity;protein binding","Pf02893, Pf06602","8898","ENSG00000087053.18","MTMR2","11","Inositol phosphate metabolism; Metabolic pathways; Phosphatidylinositol signaling system","Synthesis of PIPs at the plasma membrane; Synthesis of PIPs at the ER membrane; Synthesis of PIPs at the early endosome membrane; Synthesis of PIPs at the late endosome membrane","",11,0,0.895,-0.16,0.125184144242319,0.715910629219256,101.4,93.8,104.8,"",3.63,4.92,1222,"","",1122.8,1203.3,1110.1,1137.5,1261,1264.4,1264.4,1141.9,62,"","",896,910.8,881.5,823.8,908.2,1264.4,1030.5,911.2,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","O43175","D-3-phosphoglycerate dehydrogenase OS=Homo sapiens OX=9606 GN=PHGDH PE=1 SV=4",0,224.655,55,24,89,24,533,56.6,6.71,254.51,24,"metabolic process","cytosol","catalytic activity;nucleotide binding","Pf00389, Pf02826","26227","ENSG00000092621.11","PHGDH","1","Glycine, serine and threonine metabolism; Biosynthesis of amino acids; Carbon metabolism; Metabolic pathways","Serine biosynthesis","Trans-sulfuration and one carbon metabolism",9,0,1.097,0.13,0.127861754997751,0.72052261166856,115.1,96.8,88.2,19.72,2.32,4.72,13714.1,"",18158.5,13196.2,12709.6,13349.1,13358.1,12103.8,11902.9,12083.5,13179.2,695.8,"",2.3,10530.6,9619.9,10600.5,9674.5,8717.5,11902.9,9848.2,10516.7,"High","High","High","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q5BKZ1","DBIRD complex subunit ZNF326 OS=Homo sapiens OX=9606 GN=ZNF326 PE=1 SV=2",0,133.124,37,18,34,18,582,65.6,5.15,113.1,18,"metabolic process;regulation of biological process","nucleus;spliceosomal complex","DNA binding;metal ion binding;protein binding;RNA binding","Pf04988","284695","ENSG00000162664.16","ZNF326","1","","","",0,0,0.903,-0.15,0.130250285161145,0.72528519638081,81.3,103.7,114.9,"",2.51,2.32,1235.8,"","",1594,1596.8,1559.6,1512.6,1796.5,1749.2,1697.2,1744.7,62.7,"","",1272,1208.6,1238.5,1095.5,1293.9,1749.2,1383.2,1392.2,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q6UWW8","Carboxylesterase 3 OS=Homo sapiens OX=9606 GN=CES3 PE=1 SV=1",0,18.38,11,4,5,4,571,62.2,5.62,19.34,4,"metabolic process","cytosol;endoplasmic reticulum;organelle lumen","catalytic activity","Pf00135, Pf07859","23491","ENSG00000172828.12","CES3","16","","Phase I - Functionalization of compounds; LDL clearance","Aryl Hydrocarbon Receptor Pathway; NRF2 pathway",9,0,0.876,-0.19,0.132784257344691,0.732057516849539,93.8,96.3,109.9,"",9.51,7.25,346.9,"","",380.7,338.2,375.3,309.7,396.3,417.6,440,371.1,17.6,"","",303.8,256,298,224.3,285.4,417.6,358.6,296.1,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P82912","28S ribosomal protein S11, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS11 PE=1 SV=2",0,40.448,37,4,6,4,194,20.6,10.81,20.55,4,"cell organization and biogenesis;metabolic process;response to stimulus","membrane;mitochondrion;ribosome","RNA binding;structural molecule activity","Pf00411","64963","ENSG00000181991.15","MRPS11","15","Ribosome","Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination","",7,0,1.117,0.16,0.135274504304329,0.736329924293994,179,63.8,57.2,109.73,2.74,1.76,1354.1,10732.2,"",1354.9,1364.6,1381.9,1296.7,1217.8,1250.4,1199,1216.6,68.7,3,"",1081.2,1032.9,1097.4,939.1,877.1,1250.4,977.2,970.8,"High","High","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q15067","Peroxisomal acyl-coenzyme A oxidase 1 OS=Homo sapiens OX=9606 GN=ACOX1 PE=1 SV=3",0,88.19,33,18,20,18,660,74.4,8.16,55.34,18,"cell organization and biogenesis;metabolic process;regulation of biological process","cytoplasm;membrane;mitochondrion;nucleus;organelle lumen","catalytic activity;nucleotide binding;protein binding","Pf01756, Pf02770, Pf14749","51","ENSG00000161533.11","ACOX1","17","cAMP signaling pathway; PPAR signaling pathway; Fatty acid metabolism; Biosynthesis of unsaturated fatty acids; alpha-Linolenic acid metabolism; Peroxisome; Metabolic pathways; Fatty acid degradation","PPARA activates gene expression","Estrogen Receptor Pathway; PPAR signaling pathway",14,0,1.113,0.15,0.138087310975455,0.743274790127422,167.9,69.6,62.5,97.6,11.38,5.32,3329,"",18158.5,3210.9,3230.1,3447.7,2617.5,2883,3015.1,2906,2652.8,168.9,"",2.3,2562.3,2444.9,2737.8,1895.7,2076.4,3015.1,2368.4,2116.9,"High","Not Found","High","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","O14656","Torsin-1A OS=Homo sapiens OX=9606 GN=TOR1A PE=1 SV=1",0,21.372,17,5,5,5,332,37.8,6.99,17.31,5,"cell organization and biogenesis;cellular component movement;metabolic process;regulation of biological process;response to stimulus;transport","cytoplasm;cytoskeleton;cytosol;endoplasmic reticulum;membrane;nucleus;organelle lumen","catalytic activity;nucleotide binding;protein binding","Pf06309","1861","ENSG00000136827.11","TOR1A","9","","Cargo recognition for clathrin-mediated endocytosis","",4,0,0.873,-0.2,0.140384130817385,0.748143117494871,98.8,93.8,107.4,"",2.8,5.75,408,"","",406,381.6,390.4,384.4,459.3,447.7,439.7,401.3,20.7,"","",324,288.8,310,278.4,330.8,447.7,358.4,320.2,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q86UT8","Coiled-coil domain-containing protein 84 OS=Homo sapiens OX=9606 GN=CCDC84 PE=1 SV=1",0,13.153,14,4,4,4,332,38,8.22,11.04,4,"","","","Pf14968","338657","ENSG00000280975.2; ENSG00000186166.8","CCDC84","11; CHR_HG2217_PATCH","","","",0,0,0.853,-0.23,0.143139349906419,0.754144162927542,97.1,93.4,109.5,"",5.62,4.53,138,"","",123.4,141.6,132.1,133.5,152.3,164.7,148.8,159.2,7,"","",98.5,107.2,104.9,96.7,109.7,164.7,121.3,127,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q9HCU4","Cadherin EGF LAG seven-pass G-type receptor 2 OS=Homo sapiens OX=9606 GN=CELSR2 PE=1 SV=1",0,17.373,3,7,7,6,2923,317.3,5.31,19.04,7,"cell organization and biogenesis;development;regulation of biological process;response to stimulus","cytoplasm;membrane","metal ion binding;protein binding;receptor activity;signal transducer activity","Pf00002, Pf00008, Pf00028, Pf00053, Pf00054, Pf01825, Pf02210, Pf02793, Pf12003, Pf12947","1952","ENSG00000143126.7","CELSR2","1","","","GPCRs, Other; Ectoderm Differentiation",2,1,0.855,-0.23,0.144831268167968,0.755075117778258,116.9,84.4,98.7,"",3.37,5.13,210.9,"","",146.6,156.3,156.2,148.3,183.8,185.7,172.4,166.8,10.7,"","",117,118.3,124,107.4,132.4,185.7,140.5,133.1,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q15293","Reticulocalbin-1 OS=Homo sapiens OX=9606 GN=RCN1 PE=1 SV=1",0,130.646,58,17,40,17,331,38.9,5,119.57,17,"metabolic process","endoplasmic reticulum;organelle lumen","metal ion binding;protein binding","Pf13499","5954","ENSG00000049449.8","RCN1","11","","Post-translational protein phosphorylation; Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)","",4,0,0.909,-0.14,0.147698961208146,0.758187747883872,146.9,72.9,80.2,76.37,24.29,8.46,5128.5,17171.6,"",4536.7,4313.9,4782.2,7024,4769.9,4746.9,5517.7,5502.7,260.2,4.8,"",3620.3,3265.2,3797.5,5087.1,3435.4,4746.9,4497,4391,"High","High","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","O95073","Fibrinogen silencer-binding protein OS=Homo sapiens OX=9606 GN=FSBP PE=1 SV=1",0.004,3.014,5,1,2,1,299,34.7,7.12,6.29,1,"metabolic process;regulation of biological process;response to stimulus","nucleus","catalytic activity;DNA binding;nucleotide binding;protein binding","Pf13873","100861412; 25788","ENSG00000265817.2","FSBP; RAD54B","8","","","",0,0,0.859,-0.22,0.149138434004281,0.758187747883872,92,96.1,111.9,"",6.33,5.45,195.1,"","",199,208.9,194.4,224,255.2,223.5,237.5,237.1,9.9,"","",158.8,158.1,154.4,162.2,183.8,223.5,193.6,189.2,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P17858","ATP-dependent 6-phosphofructokinase, liver type OS=Homo sapiens OX=9606 GN=PFKL PE=1 SV=6",0,158.418,25,20,34,16,780,85,7.5,129.25,20,"cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus;transport","cytoplasm;cytosol;extracellular;membrane;organelle lumen","catalytic activity;metal ion binding;nucleotide binding;protein binding","Pf00365","5211","ENSG00000141959.16","PFKL","21","Glycolysis / Gluconeogenesis; Galactose metabolism; Biosynthesis of amino acids; Pentose phosphate pathway; Central carbon metabolism in cancer; Glucagon signaling pathway; Metabolic pathways; Carbon metabolism; RNA degradation; HIF-1 signaling pathway; AMPK signaling pathway; Fructose and mannose metabolism","Glycolysis; Neutrophil degranulation","Photodynamic therapy-induced HIF-1 survival signaling; Insulin Signaling; Glycolysis and Gluconeogenesis",22,0,1.106,0.14,0.151703640252574,0.760652603421986,108.2,100.7,91.1,"",8.66,8.77,3632.5,"","",3432.3,3330,3288.8,3944.5,3550.7,2927.9,3025,3090.9,184.3,"","",2739,2520.5,2611.6,2856.8,2557.3,2927.9,2465.4,2466.5,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q96EQ0","Small glutamine-rich tetratricopeptide repeat-containing protein beta OS=Homo sapiens OX=9606 GN=SGTB PE=1 SV=1",0,13.165,15,4,4,4,304,33.4,4.92,9.34,4,"cell organization and biogenesis;transport","","protein binding","Pf00515, Pf06552, Pf07719, Pf13181, Pf13414, Pf13424, Pf13431, Pf13432, Pf14559","54557","ENSG00000197860.9","SGTB","5","","","",0,0,0.881,-0.18,0.154006641388071,0.766100364170872,110.8,88.6,100.6,"",6,3.82,461.2,"","",360.3,389.4,338.7,377.4,428.9,414.2,392.6,422.7,23.4,"","",287.5,294.7,269,273.3,308.9,414.2,320,337.3,"High","High","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q92478","C-type lectin domain family 2 member B OS=Homo sapiens OX=9606 GN=CLEC2B PE=1 SV=2",0,14.902,30,3,5,3,149,17.3,8.75,17.54,3,"regulation of biological process","membrane","protein binding","Pf00059","9976","ENSG00000110852.4","CLEC2B","12","","Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell","",3,0,0.856,-0.22,0.15553264000505,0.768382567125959,82.2,100.5,117.3,"",14.92,18.14,80.8,"","",97.2,100.4,103,72.8,79.3,112.8,118,122.3,4.1,"","",77.6,76,81.8,52.7,57.1,112.8,96.2,97.6,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q9H444","Charged multivesicular body protein 4b OS=Homo sapiens OX=9606 GN=CHMP4B PE=1 SV=1",0,57.149,43,11,26,9,224,24.9,4.82,83.36,11,"cell communication;cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus;transport","cytoplasm;cytosol;endosome;membrane;nucleus","protein binding","Pf03357","128866","ENSG00000101421.3","CHMP4B","20","Endocytosis","Budding and maturation of HIV virion; Macroautophagy; Endosomal Sorting Complex Required For Transport (ESCRT)","",12,1,0.909,-0.14,0.159707343797082,0.776570404318022,178.1,58.1,63.9,112.72,16.56,3.69,3744.9,"",33159,3627.2,3606.3,3639.2,4932.7,3927,3764.3,4066,4075.2,190,"",4.2,2894.5,2729.6,2889.9,3572.5,2828.3,3764.3,3313.8,3251.9,"High","Not Found","High","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q9Y613","FH1/FH2 domain-containing protein 1 OS=Homo sapiens OX=9606 GN=FHOD1 PE=1 SV=3",0,78.77,17,16,18,16,1164,126.5,6.39,58.54,16,"regulation of biological process","cytoplasm;cytoskeleton;cytosol;membrane;nucleus","protein binding","Pf02181","29109","ENSG00000135723.13","FHOD1","16","","","",0,0,1.115,0.16,0.160122256703898,0.777665200864807,209.3,47.8,42.9,126.36,5.45,4.25,965.8,17171.6,"",905.3,975.7,956.7,864.5,864.9,833,836.6,780.4,49,4.8,"",722.4,738.5,759.7,626.1,622.9,833,681.8,622.7,"High","High","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q9BWN1","Proline-rich protein 14 OS=Homo sapiens OX=9606 GN=PRR14 PE=1 SV=1",0,19.164,11,5,5,5,585,64.3,10.35,15.21,5,"","chromosome;nucleus","protein binding","Pf15386","78994","ENSG00000156858.11","PRR14","16","","","",0,0,0.884,-0.18,0.163173090091576,0.780849588459511,110.7,88.8,100.5,"",1.78,1.67,435.6,"","",347.5,351.7,347.3,360.7,400.7,385.3,397.2,394.1,22.1,"","",277.3,266.2,275.8,261.2,288.6,385.3,323.7,314.5,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q9UKI8","Serine/threonine-protein kinase tousled-like 1 OS=Homo sapiens OX=9606 GN=TLK1 PE=1 SV=2",0,41.981,19,11,11,7,766,86.6,8.72,32.11,11,"cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus;transport","nucleus","catalytic activity;nucleotide binding;protein binding","Pf00069, Pf07714","9874","ENSG00000198586.13","TLK1","2","","","miRNA Regulation of DNA Damage Response; Pathways Affected in Adenoid Cystic Carcinoma; DNA Damage Response",3,2,0.899,-0.15,0.166075634763214,0.785150929189392,100.5,94.5,105,"",6.76,1.05,719.4,"","",681.8,648.2,670.4,755.7,761.3,748.1,743.5,755.8,36.5,"","",544.1,490.6,532.4,547.3,548.3,748.1,606,603.1,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q8IWE4","DCN1-like protein 3 OS=Homo sapiens OX=9606 GN=DCUN1D3 PE=1 SV=1",1E-3,4.019,5,1,1,1,304,34.3,5.12,2.64,1,"metabolic process;regulation of biological process;response to stimulus","membrane","protein binding","Pf03556","123879","ENSG00000188215.9","DCUN1D3","16","","Neddylation","",3,0,1.19,0.25,0.167929172231446,0.787644947878708,"",163,137,"",10.71,18.66,"","","",25.3,31.6,25.4,27.1,24.3,19.9,20,29.1,"","","",20.2,23.9,20.2,19.6,17.5,19.9,16.3,23.2,"Not Found","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P51531","Probable global transcription activator SNF2L2 OS=Homo sapiens OX=9606 GN=SMARCA2 PE=1 SV=2",0,135.96,21,36,42,24,1590,181.2,7.2,120.67,36,"cell organization and biogenesis;metabolic process;regulation of biological process","cytoskeleton;nucleus","catalytic activity;DNA binding;nucleotide binding;protein binding","Pf00176, Pf00270, Pf00271, Pf00439, Pf07529, Pf07533, Pf08880, Pf11496, Pf14619","6595","ENSG00000080503.22","SMARCA2","9","","RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known; RMTs methylate histone arginines","Retinoblastoma (RB) in Cancer; Pathways Affected in Adenoid Cystic Carcinoma; VEGFA-VEGFR2 Signaling Pathway",11,0,0.92,-0.12,0.171459479146545,0.791428798172029,97.1,97.2,105.7,"",2.3,2.22,2704.2,"","",2693.2,2675.5,2816.2,2721.5,2923.7,2962.9,2829,2969.5,137.2,"","",2149.2,2025.1,2236.3,1971,2105.7,2962.9,2305.7,2369.6,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q96ME7","Zinc finger protein 512 OS=Homo sapiens OX=9606 GN=ZNF512 PE=1 SV=2",0,76.83,27,14,18,14,567,64.6,9.76,53.4,14,"metabolic process;regulation of biological process","nucleus","DNA binding;metal ion binding","","84450","ENSG00000243943.9","ZNF512","2","","","",0,0,0.914,-0.13,0.172000006635365,0.7923089586304,150.8,71.3,77.9,97.27,1.54,2.06,1852.7,10016.8,"",2035.1,2053.1,2035.8,1981.1,2216,2300.9,2194,2236.4,94,2.8,"",1624,1554,1616.6,1434.8,1596,2300.9,1788.1,1784.6,"High","High","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q9H098","Protein FAM107B OS=Homo sapiens OX=9606 GN=FAM107B PE=1 SV=1",0,25.068,35,6,6,6,131,15.5,8.29,18.67,6,"","","","Pf06625","83641","ENSG00000065809.13","FAM107B","10","","","",0,0,0.9,-0.15,0.174459993725714,0.797869336922831,181.1,56.3,62.6,121.84,14.49,10.84,798.2,10732.2,"",912.9,908.4,717.2,1029.4,1017.2,1005.6,972.4,1223.8,40.5,3,"",728.5,687.6,569.5,745.5,732.6,1005.6,792.5,976.6,"High","High","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q9BXF6","Rab11 family-interacting protein 5 OS=Homo sapiens OX=9606 GN=RAB11FIP5 PE=1 SV=1",0,47.833,22,11,11,11,653,70.4,9.23,32.86,11,"regulation of biological process;response to stimulus;transport","cytoplasm;endosome;Golgi;membrane;mitochondrion","protein binding","Pf00168, Pf09457","26056","ENSG00000135631.16","RAB11FIP5","2","Endocytosis","","",1,0,1.115,0.16,0.176559487859543,0.80195637685021,186.3,59.9,53.8,108.46,5.49,4.4,2603.7,"",19737.5,2279.7,2215.9,2334.6,2514.2,1954.9,2013.9,2126.2,2144.1,132.1,"",2.5,1819.2,1677.2,1853.9,1820.9,1408,2013.9,1732.9,1710.9,"High","Not Found","High","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q8WXE9","Stonin-2 OS=Homo sapiens OX=9606 GN=STON2 PE=1 SV=1",1E-3,4.795,2,2,2,2,905,101.1,5.39,5,2,"cell differentiation;cell organization and biogenesis;regulation of biological process;transport","cytoplasm;cytosol;membrane","protein binding","Pf00928, Pf12016","85439","ENSG00000140022.9","STON2","14","","Cargo recognition for clathrin-mediated endocytosis","",4,0,0.861,-0.22,0.178817678172963,0.803968081438116,88.2,98,113.8,"",11.82,5.88,112.3,"","",135.2,121.8,128.1,101.8,137.3,145.7,158,144.4,5.7,"","",107.9,92.2,101.7,73.7,98.9,145.7,128.8,115.2,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","O95197","Reticulon-3 OS=Homo sapiens OX=9606 GN=RTN3 PE=1 SV=2",0,60.425,14,14,15,14,1032,112.5,4.96,45.96,14,"cell death;cell organization and biogenesis;regulation of biological process;transport","endoplasmic reticulum;Golgi;membrane","protein binding","Pf02453, Pf04093","10313","ENSG00000133318.13","RTN3","11","Alzheimer's disease","Synaptic adhesion-like molecules","",4,0,0.917,-0.12,0.18159770285903,0.807632043283734,98.4,96.5,105.2,"",3.75,2.04,2191.7,"","",2066.8,2206.4,2093.1,2228.5,2314.4,2395.8,2294.2,2372.1,111.2,"","",1649.3,1670,1662.1,1614,1666.9,2395.8,1869.8,1892.9,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P54826","Growth arrest-specific protein 1 OS=Homo sapiens OX=9606 GN=GAS1 PE=2 SV=2",0,39.448,26,7,8,7,345,35.7,5.55,28.1,7,"regulation of biological process;response to stimulus","membrane","protein binding","Pf02351","2619","ENSG00000180447.6","GAS1","9","Hedgehog signaling pathway","Ligand-receptor interactions; Activation of SMO","",6,0,0.875,-0.19,0.183983095829386,0.811325706313884,233.3,31.1,35.6,139.46,7.78,5.62,110.4,"",15790,184.5,167.9,194.2,165,213,196,206.5,187.5,5.6,"",2,147.2,127.1,154.2,119.5,153.4,196,168.3,149.6,"High","Not Found","High","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","O95602","DNA-directed RNA polymerase I subunit RPA1 OS=Homo sapiens OX=9606 GN=POLR1A PE=1 SV=2",0,161.73,28,37,47,36,1720,194.7,7.03,147.17,37,"metabolic process;regulation of biological process","nucleus","catalytic activity;DNA binding;metal ion binding;protein binding","Pf00623, Pf04983, Pf04997, Pf04998, Pf05000","25885","ENSG00000068654.15","POLR1A","2","Pyrimidine metabolism; RNA polymerase; Metabolic pathways; Purine metabolism","RNA Polymerase I Chain Elongation; NoRC negatively regulates rRNA expression; RNA Polymerase I Transcription Termination; RNA Polymerase I Promoter Escape; B-WICH complex positively regulates rRNA expression; RNA Polymerase I Transcription Initiation","Eukaryotic Transcription Initiation",17,1,1.091,0.13,0.187595993784994,0.81616928633688,101.3,103.7,95,"",4.44,3.01,4710.7,"","",4886.7,4788.6,4848.7,4428.5,4449.4,4641,4384.5,4335.7,239,"","",3899.6,3624.5,3850.3,3207.3,3204.6,4641,3573.4,3459.8,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P07355","Annexin A2 OS=Homo sapiens OX=9606 GN=ANXA2 PE=1 SV=2",0,270.344,72,32,240,32,339,38.6,7.75,712.29,32,"cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus;transport","cell surface;cytoplasm;cytosol;endoplasmic reticulum;endosome;extracellular;membrane;nucleus;organelle lumen","enzyme regulator activity;metal ion binding;protein binding;RNA binding","Pf00191","302","ENSG00000182718.16","ANXA2","15","","Dissolution of Fibrin Clot; Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation; Smooth Muscle Contraction; Neutrophil degranulation; Interleukin-12 family signaling","Prostaglandin Synthesis and Regulation",12,0,0.923,-0.12,0.191849756568796,0.824616747365811,75,108,117,47.37,8.48,2.38,20823.5,10374.5,"",20402.7,21983.1,20407.9,24312.3,22800.7,23097.2,22032.3,23255.7,1056.5,2.9,"",16281.4,16639,16205.8,17608,16421.7,23097.2,17956.6,18557.5,"High","High","High","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P51991","Heterogeneous nuclear ribonucleoprotein A3 OS=Homo sapiens OX=9606 GN=HNRNPA3 PE=1 SV=2",0,208.233,61,26,88,23,378,39.6,9.01,282.75,26,"metabolic process;transport","cytoplasm;nucleus;spliceosomal complex","protein binding;RNA binding;transporter activity","Pf00076, Pf13893, Pf14259","220988","ENSG00000170144.20","HNRNPA3","2","Spliceosome","mRNA Splicing - Major Pathway","",5,0,0.923,-0.12,0.19117216887787,0.824616747365811,163.6,65.4,70.9,100.66,3.17,4.83,7046.3,"",41843.6,7201.6,6820,6913.3,6685.1,7096.2,7303.7,7579.8,7930.2,357.5,"",5.3,5746.9,5162.1,5489.8,4841.6,5110.9,7303.7,6177.6,6328.1,"High","Not Found","High","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q9NZW5","MAGUK p55 subfamily member 6 OS=Homo sapiens OX=9606 GN=MPP6 PE=1 SV=2",0,75.792,38,17,20,16,540,61.1,6.18,49.5,17,"cell organization and biogenesis","membrane","protein binding","Pf00018, Pf00595, Pf00625, Pf02828, Pf07653, Pf13180, Pf14604, Pf14685","51678","ENSG00000105926.15","MPP6","7","","","",0,1,1.098,0.14,0.194652223088639,0.82936864193508,173.9,66,60.1,106.15,5.58,2.55,2924.9,"",20527,2895.1,3001.5,2987.4,2653.8,2629.2,2754.2,2726.7,2618.5,148.4,"",2.6,2310.3,2271.8,2372.3,1922,1893.6,2754.2,2222.3,2089.5,"High","Not Found","High","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q9UF56","F-box/LRR-repeat protein 17 OS=Homo sapiens OX=9606 GN=FBXL17 PE=1 SV=3",0,6.055,2,2,2,2,701,75.6,8.07,5.7,2,"","","protein binding","Pf00646, Pf12937","64839","ENSG00000145743.15","FBXL17","5","","","",0,0,1.189,0.25,0.196245068217267,0.830310839781743,"",163,137,"",15.61,9.01,"","","",18.5,23.4,21.3,16.3,17.9,15.2,15.6,18,"","","",14.8,17.7,16.9,11.8,12.9,15.2,12.7,14.4,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P52788","Spermine synthase OS=Homo sapiens OX=9606 GN=SMS PE=1 SV=2",0,91.505,55,20,33,20,366,41.2,5.02,94.39,20,"metabolic process","cytosol","catalytic activity","Pf01564","6611","ENSG00000102172.15","SMS","X","Metabolic pathways; Glutathione metabolism; Cysteine and methionine metabolism; beta-Alanine metabolism; Arginine and proline metabolism","Metabolism of polyamines","Amino Acid metabolism; Urea cycle and metabolism of amino groups",10,0,1.097,0.13,0.198518139272182,0.83121494448525,92.1,108.8,99.1,"",4.68,2.81,2625.4,"","",3108.4,3093,2955.2,3309,2837.4,2813.3,2780.6,2963.9,133.2,"","",2480.5,2341.1,2346.7,2396.5,2043.6,2813.3,2266.2,2365.1,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,"Acetyl [N-Term]"]
[false,"High","Master Protein","Q9H6K1","Protein ILRUN OS=Homo sapiens OX=9606 GN=ILRUN PE=1 SV=2",0,31.677,27,6,7,6,298,32.9,4.58,25.21,6,"cell communication;metabolic process;response to stimulus","vacuole","protein binding","Pf14555","64771","ENSG00000196821.9","C6orf106","6","","","",0,0,0.899,-0.15,0.199024980448324,0.831664293277754,79.1,104.5,116.3,"",4.6,3.35,327.2,"","",438.6,450.9,426,404.6,475.3,486.7,508,472.1,16.6,"","",350,341.3,338.3,293,342.3,486.7,414,376.7,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q86SF2","N-acetylgalactosaminyltransferase 7 OS=Homo sapiens OX=9606 GN=GALNT7 PE=1 SV=1",0,73.141,31,17,22,17,657,75.3,7.11,63.21,17,"metabolic process","Golgi;membrane","catalytic activity;metal ion binding","Pf00535, Pf00652, Pf02709, Pf10111","51809","ENSG00000109586.11","GALNT7","4","Mucin type O-glycan biosynthesis; Metabolic pathways","O-linked glycosylation of mucins","",6,0,1.09,0.12,0.202856880574678,0.832576694065199,178.9,63.1,57.9,91.55,4.4,1.55,4933.4,12878.7,37106.5,4515,4572.9,4797.9,4311.7,4266.7,4191,4148.2,4116.7,250.3,3.6,4.7,3603,3461.2,3810,3122.7,3073,4191,3380.8,3285,"High","High","High","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q02750","Dual specificity mitogen-activated protein kinase kinase 1 OS=Homo sapiens OX=9606 GN=MAP2K1 PE=1 SV=2",0,72.389,38,16,27,11,393,43.4,6.62,52.83,16,"cell differentiation;cell proliferation;cellular component movement;metabolic process;regulation of biological process;response to stimulus","cytoplasm;cytoskeleton;cytosol;endoplasmic reticulum;endosome;Golgi;membrane;mitochondrion;nucleus","catalytic activity;enzyme regulator activity;nucleotide binding;protein binding;signal transducer activity","Pf00069, Pf07714","5604","ENSG00000169032.9","MAP2K1","15","Serotonergic synapse; Central carbon metabolism in cancer; Acute myeloid leukemia; Pathways in cancer; Melanogenesis; Fc epsilon RI signaling pathway; Estrogen signaling pathway; Hepatitis B; Neurotrophin signaling pathway; Colorectal cancer; Melanoma; Sphingolipid signaling pathway; Signaling pathways regulating pluripotency of stem cells; Osteoclast differentiation; Phospholipase D signaling pathway; Oxytocin signaling pathway; Glioma; Long-term depression; Endocrine resistance; T cell receptor signaling pathway; FoxO signaling pathway; Non-small cell lung cancer; Prostate cancer; Proteoglycans in cancer; Alcoholism; Cholinergic synapse; HIF-1 signaling pathway; VEGF signaling pathway; Natural killer cell mediated cytotoxicity; Apoptosis; Bladder cancer; cAMP signaling pathway; Vascular smooth muscle contraction; Chronic myeloid leukemia; Endometrial cancer; Renal cell carcinoma; Oocyte meiosis; GnRH signaling pathway; TNF signaling pathway; MicroRNAs in cancer; Progesterone-mediated oocyte maturation; Thyroid hormone signaling pathway; mTOR signaling pathway; Ras signaling pathway; Pancreatic cancer; Focal adhesion; Insulin signaling pathway; EGFR tyrosine kinase inhibitor resistance; Prion diseases; Gap junction; Dorso-ventral axis formation; Long-term potentiation; PI3K-Akt signaling pathway; ErbB signaling pathway; Influenza A; Breast cancer; Chemokine signaling pathway; MAPK signaling pathway; Fc gamma R-mediated phagocytosis; Rap1 signaling pathway; Thyroid cancer; B cell receptor signaling pathway; Toll-like receptor signaling pathway; cGMP-PKG signaling pathway; Regulation of actin cytoskeleton; Prolactin signaling pathway; Choline metabolism in cancer","MAP2K and MAPK activation; Uptake and function of anthrax toxins; MAP3K8 (TPL2)-dependent MAPK1/3 activation; Activated TLR4 signalling; Negative feedback regulation of MAPK pathway; Interleukin-1 family signaling; Paradoxical activation of RAF signaling by kinase inactive BRAF; Interleukin-20 family signaling; Signaling by BRAF and RAF fusions; Signal transduction by L1; MAPK3 (ERK1) activation; Signaling by RAS mutants; Signaling by high-kinase activity BRAF mutants; Signaling by moderate kinase activity BRAF mutants; RAF activation","IL-5 Signaling Pathway; Osteopontin Signaling; Regulation of toll-like receptor signaling pathway; MicroRNAs in cardiomyocyte hypertrophy; Integrin-mediated Cell Adhesion; IL-1 signaling pathway; RANKL/RANK (Receptor activator of NFKB (ligand)) Signaling Pathway; Human Thyroid Stimulating Hormone (TSH) signaling pathway; Leptin signaling pathway; Prolactin Signaling Pathway; IL-7 Signaling Pathway; Endothelin Pathways; IL-9 Signaling Pathway; Signaling Pathways in Glioblastoma; B Cell Receptor Signaling Pathway; AGE/RAGE pathway; Interleukin-11 Signaling Pathway; Corticotropin-releasing hormone signaling pathway; Oncostatin M Signaling Pathway; Brain-Derived Neurotrophic Factor (BDNF) signaling pathway; Aryl Hydrocarbon Receptor; Common Pathways Underlying Drug Addiction; Structural Pathway of Interleukin 1 (IL-1); Cardiac Hypertrophic Response; Bladder Cancer; IL-3 Signaling Pathway; Kit receptor signaling pathway; Focal Adhesion; Signaling of Hepatocyte Growth Factor Receptor; IL-6 signaling pathway; TGF-beta Signaling Pathway; BDNF-TrkB Signaling; Association Between Physico-Chemical Features and Toxicity Associated Pathways; MAPK Signaling Pathway; T-Cell antigen Receptor (TCR) pathway during Staphylococcus aureus infection; 4-hydroxytamoxifen, Dexamethasone, and Retinoic Acids Regulation of p27 Expression; VEGFA-VEGFR2 Signaling Pathway; Angiopoietin Like Protein 8 Regulatory Pathway; Chemokine signaling pathway; ESC Pluripotency Pathways; Focal Adhesion-PI3K-Akt-mTOR-signaling pathway; MAPK Cascade; EGF/EGFR Signaling Pathway; Insulin Signaling; IL-2 Signaling Pathway; Regulation of Actin Cytoskeleton; EPO Receptor Signaling; Senescence and Autophagy in Cancer; ErbB Signaling Pathway; T-Cell antigen Receptor (TCR)  Signaling Pathway; Estrogen signaling pathway; Serotonin Receptor 2 and ELK-SRF/GATA4 signaling; Serotonin Receptor 4/6/7 and NR3C Signaling; Toll-like receptor signaling pathway",172,0,1.102,0.14,0.208794836057046,0.838749107827325,106,101.7,92.3,"",2.97,8.02,2562.3,"","",2541.3,2455.9,2462.9,2363.3,2576.1,2207,2256,2175.4,130,"","",2028,1858.9,1955.8,1711.6,1855.4,2207,1838.7,1735.9,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q9NYZ1","Golgi apparatus membrane protein TVP23 homolog B OS=Homo sapiens OX=9606 GN=TVP23B PE=1 SV=2",0,6.704,10,2,2,2,205,23.6,8.35,6.24,2,"transport","membrane","","Pf05832","51030","ENSG00000171928.13","FAM18B1; TVP23B","17","","","",0,0,1.172,0.23,0.208337209961794,0.838749107827325,"",161.9,138.1,"",75.9,66.5,"","","",20.7,26.6,20.1,76.9,51.1,24.9,12.6,16,"","","",16.5,20.1,16,55.7,36.8,24.9,10.3,12.8,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q30201","Hereditary hemochromatosis protein OS=Homo sapiens OX=9606 GN=HFE PE=1 SV=1",0,11.858,9,3,3,3,348,40.1,6.6,8.45,3,"cell communication;cell organization and biogenesis;cellular homeostasis;defense response;metabolic process;regulation of biological process;response to stimulus;transport","cytoskeleton;endosome;membrane","protein binding","Pf00129, Pf07654","3077","ENSG00000010704.18","HFE","6","","Transferrin endocytosis and recycling","Hfe effect on hepcidin production",4,0,1.161,0.22,0.210628418220151,0.839314253869667,"",161.2,138.8,"",5.53,24.29,"","","",36.5,40.3,37.7,41,50.3,32.2,35,30.7,"","","",29.1,30.5,29.9,29.7,36.2,32.2,28.5,24.5,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P17661","Desmin OS=Homo sapiens OX=9606 GN=DES PE=1 SV=3",0,38.658,10,7,54,1,470,53.5,5.27,144.69,7,"cell organization and biogenesis;cellular component movement;regulation of biological process","cytoplasm;cytoskeleton;cytosol;membrane;nucleus","protein binding;structural molecule activity","Pf00038, Pf03962, Pf04732","1674","ENSG00000175084.11","DES","2","Dilated cardiomyopathy; Arrhythmogenic right ventricular cardiomyopathy (ARVC); Hypertrophic cardiomyopathy (HCM)","Striated Muscle Contraction","Arrhythmogenic Right Ventricular Cardiomyopathy; Striated Muscle Contraction",7,0,1.121,0.16,0.211843631380474,0.840188645331785,83.5,114.4,102.1,"",11.28,18.48,244.4,"","",337.3,332.5,318.7,406.6,396,311.6,262.7,286.5,12.4,"","",269.2,251.7,253.1,294.5,285.2,311.6,214.1,228.6,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P52758","2-iminobutanoate/2-iminopropanoate deaminase OS=Homo sapiens OX=9606 GN=RIDA PE=1 SV=1",0,17.006,27,3,5,3,137,14.5,8.68,16.71,3,"metabolic process;regulation of biological process;response to stimulus","cytoplasm;cytosol;mitochondrion;nucleus;organelle lumen","catalytic activity;metal ion binding;protein binding;RNA binding","Pf01042","10247","ENSG00000132541.10","HRSP12; RIDA","8","","","",0,0,1.116,0.16,0.215873791442277,0.843663184928973,95.4,107.9,96.7,"",6.28,7.75,408,"","",452.5,472.2,470.1,411.1,422.2,404.5,422.6,356.5,20.7,"","",361.1,357.4,373.3,297.7,304.1,404.5,344.4,284.5,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q96RN5","Mediator of RNA polymerase II transcription subunit 15 OS=Homo sapiens OX=9606 GN=MED15 PE=1 SV=2",0,25.339,12,8,8,8,788,86.7,9.42,23.38,8,"metabolic process;regulation of biological process","cytoplasm;membrane;nucleus","protein binding","Pf09606","51586","ENSG00000099917.17","MED15","22","","Transcriptional regulation of white adipocyte differentiation; PPARA activates gene expression; Generic Transcription Pathway","Sterol Regulatory Element-Binding Proteins (SREBP) signalling; SREBF and miR33 in cholesterol and lipid homeostasis",11,0,0.922,-0.12,0.217776368648441,0.845476182843448,96.8,97.5,105.7,"",0.69,3.13,1811.3,"","",1829.6,1804.5,1816.5,1831.4,1983.7,2074.2,1969.8,1926.3,91.9,"","",1460,1365.8,1442.5,1326.4,1428.7,2074.2,1605.4,1537.1,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q5SRI9","Glycoprotein endo-alpha-1,2-mannosidase OS=Homo sapiens OX=9606 GN=MANEA PE=1 SV=1",0,6.523,7,2,2,2,462,53.6,9.11,6.02,2,"","Golgi;membrane","catalytic activity","Pf14488","79694","ENSG00000172469.15","MANEA","6","","N-glycan trimming and elongation in the cis-Golgi","",5,0,1.139,0.19,0.220224530800033,0.847927132581169,"",159.7,140.3,"",16.39,4.04,"","","",67.4,49.3,59.4,47.9,48.3,50.8,46.7,46.6,"","","",53.8,37.3,47.2,34.7,34.8,50.8,38.1,37.2,"Not Found","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q7Z628","Neuroepithelial cell-transforming gene 1 protein OS=Homo sapiens OX=9606 GN=NET1 PE=1 SV=1",0,5.843,3,2,2,2,596,67.7,9.23,6.01,2,"cellular component movement;regulation of biological process;response to stimulus","cytoplasm;cytosol;membrane;nucleus","protein binding","Pf00169, Pf00621, Pf15405","10276","ENSG00000173848.18","NET1","10","","G alpha (12/13) signalling events; NRAGE signals death through JNK; Signalling by NGF; Rho GTPase cycle","Apoptosis-related network due to altered Notch3 in ovarian cancer",12,0,0.874,-0.19,0.223752546552514,0.855340639401717,75.6,104.6,119.7,"",2.38,4.06,92.6,"","",125.7,128.9,127.3,132.8,146.6,154.7,140.1,146.6,4.7,"","",100.3,97.6,101.1,96.2,105.6,154.7,114.2,117,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q6KCM7","Calcium-binding mitochondrial carrier protein SCaMC-2 OS=Homo sapiens OX=9606 GN=SLC25A25 PE=1 SV=1",0,12.755,7,3,4,3,469,52.6,8.35,13.41,3,"metabolic process;response to stimulus;transport","membrane;mitochondrion","metal ion binding;transporter activity","Pf00153, Pf13405, Pf13499, Pf13833","114789","ENSG00000148339.12","SLC25A25","9","","","",0,0,0.891,-0.17,0.228411045380759,0.863709274304658,67.4,109.6,123,"",3.57,4.65,163.6,"","",265.2,266.6,281.2,258.5,297.8,299.1,292.6,324.2,8.3,"","",211.6,201.8,223.3,187.2,214.5,299.1,238.5,258.7,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P48681","Nestin OS=Homo sapiens OX=9606 GN=NES PE=1 SV=2",0,139.785,24,34,36,34,1621,177.3,4.36,109.51,34,"cell organization and biogenesis;cell proliferation;development;regulation of biological process","cytoplasm;cytoskeleton","protein binding;structural molecule activity","Pf00038","10763","ENSG00000132688.10","NES","1","","","",0,0,0.928,-0.11,0.230650792757975,0.863786928752891,131.6,81.1,87.3,70.47,5.37,3.35,2635.2,7870.3,"",2778.1,2930.2,2831,2575.9,2964.8,3120,3079.8,2901.7,133.7,2.2,"",2216.9,2217.9,2248.1,1865.6,2135.3,3120,2510.1,2315.5,"High","High","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P10109","Adrenodoxin, mitochondrial OS=Homo sapiens OX=9606 GN=FDX1 PE=1 SV=1",0,20.138,22,6,9,6,184,19.4,5.83,22.33,6,"metabolic process;response to stimulus;transport","mitochondrion;organelle lumen","metal ion binding","Pf00111","2230","ENSG00000137714.2","FDX1","11","","Endogenous sterols; Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR); Electron transport from NADPH to Ferredoxin; Pregnenolone biosynthesis","",15,0,0.922,-0.12,0.232062151633158,0.863786928752891,190.3,52.6,57.1,113.44,11.96,11.14,1570.9,14309.7,"",1333,1291.5,1370.1,1037.6,1232.2,1427.4,1620.8,1418.6,79.7,4,"",1063.7,977.5,1088,751.5,887.5,1427.4,1321,1132,"High","High","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P11413","Glucose-6-phosphate 1-dehydrogenase OS=Homo sapiens OX=9606 GN=G6PD PE=1 SV=4",0,194.307,50,23,86,23,515,59.2,6.84,269.45,23,"metabolic process;regulation of biological process;response to stimulus","cytoplasm;cytosol;membrane;nucleus","catalytic activity;nucleotide binding;protein binding","Pf00479, Pf02781","2539","ENSG00000160211.15","G6PD","X","Metabolic pathways; Glutathione metabolism; Central carbon metabolism in cancer; Pentose phosphate pathway; Carbon metabolism","TP53 Regulates Metabolic Genes; Pentose phosphate pathway (hexose monophosphate shunt)","Glutathione metabolism; Pentose Phosphate Pathway; Cori Cycle; NRF2 pathway; ATM Signaling Network in Development and Disease; Sulfation Biotransformation Reaction",19,0,1.075,0.1,0.235999641027685,0.865108890679682,130,88.1,81.9,52.66,2.96,0.15,9748.5,"",21316.5,10018.2,9913.6,9617.5,9383.9,9079.6,9086.4,9069.7,9102,494.6,"",2.7,7994.6,7503.6,7637.2,6796.2,6539.4,9086.4,7391.9,7263.2,"High","Not Found","High","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q8N2Z9","Centromere protein S OS=Homo sapiens OX=9606 GN=CENPS PE=1 SV=1",0,18.875,32,5,5,5,138,15.9,6.05,14.31,5,"cell division;cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus","chromosome;cytosol;nucleus","DNA binding;protein binding","Pf02291, Pf15511, Pf15630","378708; 100526739","ENSG00000175279.21; ENSG00000251503.8","APITD1; CENPS; APITD1-CORT; CENPS-CORT","1","Fanconi anemia pathway","Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal; Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; Fanconi Anemia Pathway; Deposition of new CENPA-containing nucleosomes at the centromere","",22,0,0.911,-0.13,0.237612678525972,0.867587139377257,95.4,97.5,107,"",15.82,11.5,532.2,"","",583,507.5,605.8,420.6,495.7,566.6,642.2,628.8,27,"","",465.2,384.1,481.1,304.6,357,566.6,523.4,501.8,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q2YD98","UV-stimulated scaffold protein A OS=Homo sapiens OX=9606 GN=UVSSA PE=1 SV=2",0,23.847,9,5,5,5,709,80.5,6.3,17.63,5,"metabolic process;response to stimulus","chromosome","protein binding","Pf09740","57654","ENSG00000163945.15","UVSSA","4","","Dual incision in TC-NER; Formation of TC-NER Pre-Incision Complex; Gap-filling DNA repair synthesis and ligation in TC-NER","",6,0,0.878,-0.19,0.239983338176997,0.871411054348889,35.9,123.5,140.7,"",5.72,2.88,41.4,"","",136.2,152.6,148.3,137,159.7,165.1,158.3,168.3,2.1,"","",108.7,115.5,117.8,99.2,115,165.1,129,134.3,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q9UQ53","Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase B OS=Homo sapiens OX=9606 GN=MGAT4B PE=1 SV=1",0,12.549,6,3,3,3,548,63.2,7.87,7.9,3,"metabolic process","Golgi;membrane","catalytic activity;metal ion binding","Pf04666","11282","ENSG00000161013.16; ENSG00000284501.1","MGAT4B","5; CHR_HG30_PATCH","N-Glycan biosynthesis; Metabolic pathways","N-Glycan antennae elongation","",8,0,1.108,0.15,0.241046669901023,0.871820940250594,219.8,42.2,38,135.14,10.98,8.18,195.1,8585.8,"",244.7,251.7,258.7,200.5,215.6,232.5,242.3,201.1,9.9,2.4,"",195.3,190.5,205.4,145.2,155.3,232.5,197.5,160.5,"High","High","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q5BKY9","Protein FAM133B OS=Homo sapiens OX=9606 GN=FAM133B PE=1 SV=1",0,12.6,18,3,5,3,247,28.4,10.02,15.08,3,"","","RNA binding","","257415","ENSG00000234545.7","FAM133B","7","","","",0,0,0.897,-0.16,0.243815754073913,0.872268742109261,108.5,90.6,101,"",6.19,4.23,382.4,"","",314.4,324.1,297.8,345.3,349.9,364.1,331.7,362,19.4,"","",250.9,245.3,236.5,250.1,252,364.1,270.3,288.9,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q99536","Synaptic vesicle membrane protein VAT-1 homolog OS=Homo sapiens OX=9606 GN=VAT1 PE=1 SV=2",0,45.991,22,6,16,6,393,41.9,6.29,50.5,6,"metabolic process;regulation of biological process;transport","cytoplasm;extracellular;membrane;mitochondrion;organelle lumen","catalytic activity;metal ion binding","Pf00107, Pf08240, Pf13602","10493","ENSG00000108828.15","VAT1","17","","Neutrophil degranulation","",3,0,1.097,0.13,0.246333137606838,0.875777938139954,95.9,106.8,97.3,"",7.64,3.97,2166.1,"","",2443.3,2382.1,2294.8,2729.6,2242.1,2217.8,2181.3,2048.4,109.9,"","",1949.8,1803,1822.3,1976.9,1614.8,2217.8,1777.8,1634.6,"High","Not Found","High","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q13472","DNA topoisomerase 3-alpha OS=Homo sapiens OX=9606 GN=TOP3A PE=1 SV=1",0,43.745,12,12,15,12,1001,112.3,8.34,46.67,12,"metabolic process;regulation of biological process","chromosome;nucleus","catalytic activity;DNA binding;metal ion binding;protein binding","Pf01131, Pf01396, Pf01751, Pf06839","7156","ENSG00000177302.14; ENSG00000284238.1","TOP3A","17; CHR_HSCHR17_3_CTG1","Fanconi anemia pathway; Homologous recombination","G2/M DNA damage checkpoint; Presynaptic phase of homologous DNA pairing and strand exchange; Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA); Meiotic recombination; Processing of DNA double-strand break ends; HDR through Single Strand Annealing (SSA); Regulation of TP53 Activity through Phosphorylation; Resolution of D-loop Structures through Holliday Junction Intermediates","",27,0,0.924,-0.11,0.249010945237577,0.878055065985016,100.8,95.7,103.5,"",1.89,1.68,1097.8,"","",1022.1,1026.3,1059.1,1057.1,1104,1135.5,1146.7,1118.1,55.7,"","",815.6,776.8,841,765.6,795.1,1135.5,934.6,892.2,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P26640","Valine--tRNA ligase OS=Homo sapiens OX=9606 GN=VARS PE=1 SV=4",0,250.704,35,43,88,43,1264,140.4,7.59,266.42,43,"metabolic process;regulation of biological process","cytoplasm;cytosol;mitochondrion","catalytic activity;nucleotide binding;protein binding","Pf00043, Pf00133, Pf08264, Pf09334, Pf13603","7407; 57176","ENSG00000096171.14; ENSG00000204394.12; ENSG00000226589.9","VARS; VARS2","6; CHR_HSCHR6_MHC_DBB_CTG1; CHR_HSCHR6_MHC_COX_CTG1","Aminoacyl-tRNA biosynthesis","Cytosolic tRNA aminoacylation","Amino Acid metabolism",6,0,1.073,0.1,0.250684332432881,0.88026132570966,96.3,105.4,98.3,15.94,4.68,3.55,10767.5,8585.8,"",10503.8,10547.5,10757.8,9657.7,9689.9,9937.6,10101.5,9304.3,546.3,2.4,"",8382.1,7983.4,8542.7,6994.5,6978.9,9937.6,8232.8,7424.6,"High","High","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"Medium","Master Protein","O75398","Deformed epidermal autoregulatory factor 1 homolog OS=Homo sapiens OX=9606 GN=DEAF1 PE=1 SV=1",0.016,2.057,1,1,1,1,565,59.3,5.34,2.27,1,"defense response;development;metabolic process;regulation of biological process;response to stimulus","cytoplasm;extracellular;nucleus","DNA binding;metal ion binding;protein binding","Pf01342, Pf01753","10522","ENSG00000177030.16","DEAF1","11","","","Sudden Infant Death Syndrome (SIDS) Susceptibility Pathways",1,0,0.864,-0.21,0.252942682684715,0.88048245492139,"",139.1,160.9,"",14.05,3.6,"","","",36,35.1,39.9,28.2,40.8,42.1,41.5,38.7,"","","",28.7,26.6,31.7,20.4,29.4,42.1,33.8,30.9,"Not Found","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q8WWQ0","PH-interacting protein OS=Homo sapiens OX=9606 GN=PHIP PE=1 SV=2",0,170.51,25,39,43,36,1821,206.6,8.85,129.18,39,"cell organization and biogenesis;regulation of biological process;response to stimulus","nucleus","protein binding","Pf00400, Pf00439","55023","ENSG00000146247.13","PHIP","6","","","",0,2,0.926,-0.11,0.256174642337235,0.88532924623433,92.2,99.9,107.9,"",4.15,0.66,3468.9,"","",3668.7,3693.9,3823.7,4013,4051.6,4063.4,4048.2,4106.3,176,"","",2927.6,2795.9,3036.4,2906.4,2918.1,4063.4,3299.3,3276.7,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q9Y217","Myotubularin-related protein 6 OS=Homo sapiens OX=9606 GN=MTMR6 PE=1 SV=3",0,47.118,22,13,16,13,621,71.9,7.66,48.92,13,"metabolic process;transport","cytoplasm;cytosol;nucleus","catalytic activity;protein binding;receptor activity;signal transducer activity;transporter activity","Pf06602","9107","ENSG00000139505.11","MTMR6","13","Phosphatidylinositol signaling system; Metabolic pathways; Inositol phosphate metabolism","Synthesis of PIPs at the plasma membrane","",8,0,1.087,0.12,0.259156654177368,0.888398875495765,85,112,103,"",1.28,2.04,478.9,"","",644.6,626.1,629.3,632.5,588.8,594.3,571.3,571.6,24.3,"","",514.4,473.9,499.7,458.1,424.1,594.3,465.6,456.1,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q9UHJ6","Sedoheptulokinase OS=Homo sapiens OX=9606 GN=SHPK PE=1 SV=3",0,11.23,6,3,3,3,478,51.5,6.83,7.73,3,"metabolic process;regulation of biological process;response to stimulus","cytoplasm;cytosol","catalytic activity;nucleotide binding","Pf00370","23729","","SHPK","17","","Pentose phosphate pathway (hexose monophosphate shunt)","",3,0,1.112,0.15,0.261441290246692,0.890229509677215,90.8,110.2,99.1,"",11.55,11.15,65,"","",72.8,80.6,77.3,94.6,83.4,67.8,65.3,74.3,3.3,"","",58.1,61,61.4,68.5,60.1,67.8,53.2,59.3,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q96G25","Mediator of RNA polymerase II transcription subunit 8 OS=Homo sapiens OX=9606 GN=MED8 PE=1 SV=2",0,18.544,24,6,7,6,268,29.1,7.44,17.5,6,"metabolic process;regulation of biological process","nucleus","protein binding","Pf10232","112950","ENSG00000159479.16","MED8","1","Herpes simplex infection","Transcriptional regulation of white adipocyte differentiation; PPARA activates gene expression; Generic Transcription Pathway","",10,0,0.911,-0.14,0.263790583483534,0.892117554312799,97.1,96.7,106.2,"",4.03,1.27,636.6,"","",613.3,640,628.9,673.9,696.6,690.6,696.9,711.6,32.3,"","",489.4,484.4,499.4,488.1,501.7,690.6,568,567.8,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P28715","DNA repair protein complementing XP-G cells OS=Homo sapiens OX=9606 GN=ERCC5 PE=1 SV=3",0,102.097,20,17,21,17,1186,133,5.22,81.27,17,"cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus","nucleus","catalytic activity;DNA binding;metal ion binding;protein binding","Pf00752, Pf00867","2073","ENSG00000134899.18","ERCC5","13","Nucleotide excision repair","Dual incision in TC-NER; Formation of Incision Complex in GG-NER; Dual Incision in GG-NER","",8,0,0.929,-0.11,0.266359528263616,0.894871935778043,85.5,103.3,111.2,"",1.65,2.8,1356,"","",1629.2,1593.6,1646.8,1653.9,1684.7,1743.7,1793,1783,68.8,"","",1300.1,1206.2,1307.7,1197.8,1213.4,1743.7,1461.3,1422.8,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P62877","E3 ubiquitin-protein ligase RBX1 OS=Homo sapiens OX=9606 GN=RBX1 PE=1 SV=1",0,18.314,15,2,5,2,108,12.3,6.96,17.09,2,"cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus","cytoplasm;cytosol;nucleus","catalytic activity;metal ion binding;protein binding","Pf00097, Pf12678, Pf12861, Pf13639","9978","ENSG00000100387.8","RBX1","22","Oocyte meiosis; Protein processing in endoplasmic reticulum; Nucleotide excision repair; Ubiquitin mediated proteolysis; Circadian rhythm; TGF-beta signaling pathway; Wnt signaling pathway; Renal cell carcinoma; Pathways in cancer; Cell cycle; HIF-1 signaling pathway","FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; NOTCH1 Intracellular Domain Regulates Transcription; Regulation of RAS by GAPs; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; Vif-mediated degradation of APOBEC3G; Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants; Antigen processing: Ubiquitination & Proteasome degradation; GLI3 is processed to GLI3R by the proteasome; Interleukin-1 family signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; Formation of Incision Complex in GG-NER; DNA Damage Recognition in GG-NER; Recognition of DNA damage by PCNA-containing replication complex; Interleukin-20 family signaling; Regulation of RUNX2 expression and activity; Hedgehog 'on' state; Gap-filling DNA repair synthesis and ligation in TC-NER; Degradation of DVL; Formation of TC-NER Pre-Incision Complex; Dual Incision in GG-NER; Prolactin receptor signaling; Neddylation; Degradation of beta-catenin by the destruction complex; Constitutive Signaling by NOTCH1 PEST Domain Mutants; Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling; Dual incision in TC-NER; Regulation of expression of SLITs and ROBOs","Dual hijack model of Vif in HIV infection; TGF-beta Signaling Pathway",87,0,1.106,0.15,0.268503355815413,0.895999628111176,111.2,99.2,89.6,"",23.59,6.56,360.7,"","",331.6,312.2,337.4,190.5,268.5,315.3,291.4,290.2,18.3,"","",264.6,236.3,267.9,138,193.4,315.3,237.5,231.6,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q9Y6M0-3","Isoform 3 of Testisin OS=Homo sapiens OX=9606 GN=PRSS21",0,33.792,15,4,6,1,300,33.5,7.69,22.72,4,"metabolic process","cytoplasm;extracellular;membrane","catalytic activity;protein binding","Pf00089","10942","ENSG00000282838.1; ENSG00000007038.10","PRSS21","16; CHR_HSCHR16_5_CTG1","","","",0,0,1.107,0.15,0.270309499750025,0.897136853150321,103.7,103.1,93.2,"",5.03,7.92,207,"","",201,192.4,215.3,211,191.2,181.1,160.9,191.4,10.5,"","",160.4,145.6,171,152.8,137.7,181.1,131.1,152.7,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P23786","Carnitine O-palmitoyltransferase 2, mitochondrial OS=Homo sapiens OX=9606 GN=CPT2 PE=1 SV=2",0,128.806,43,25,39,25,658,73.7,8.18,118.12,25,"metabolic process;regulation of biological process;transport","membrane;mitochondrion","catalytic activity","Pf00755","1376","ENSG00000157184.6","CPT2","1","Fatty acid metabolism; Fatty acid degradation; PPAR signaling pathway","Import of palmitoyl-CoA into the mitochondrial matrix; PPARA activates gene expression","Fatty Acid Beta Oxidation; PPAR Alpha Pathway; Mitochondrial LC-Fatty Acid Beta-Oxidation; PPAR signaling pathway",13,0,1.069,0.1,0.275489343862728,0.898960000223721,141.2,82,76.8,69,3.2,1.49,7336,"",21316.5,7275,7162.1,7690.8,7257.3,6766.8,6852.9,6628.6,6830,372.2,"",2.7,5805.5,5421,6107.2,5256,4873.6,6852.9,5402.4,5450.2,"High","Not Found","High","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q9H3K6","BolA-like protein 2 OS=Homo sapiens OX=9606 GN=BOLA2 PE=1 SV=1",0,20.576,51,3,7,3,86,10.1,6.52,27.19,3,"cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus","cytoplasm;cytosol;nucleus","protein binding","Pf01722","654483; 552900; 107984053","","BOLA2B; BOLA2; LOC107984053","16","","Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation; Interleukin-12 family signaling","",5,0,1.094,0.13,0.275665813985036,0.898960000223721,98.8,105.1,96.1,"",7.93,5,1046.6,"","",1128.4,1216.3,1099.6,1002.4,987.5,1050.5,1076.3,968.3,53.1,"","",900.5,920.6,873.2,726,711.2,1050.5,877.2,772.7,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P42858","Huntingtin OS=Homo sapiens OX=9606 GN=HTT PE=1 SV=2",0,104.214,10,26,27,26,3142,347.4,6.2,78.77,26,"cell death;cell organization and biogenesis;cellular component movement;regulation of biological process;response to stimulus;transport","cytoplasm;cytosol;endoplasmic reticulum;endosome;Golgi;membrane;nucleus;vacuole","protein binding;transporter activity","Pf12372","3064","ENSG00000197386.10","HTT","4","Huntington's disease","","Mesodermal Commitment Pathway",2,0,1.092,0.13,0.277952289214344,0.900973926913462,99.3,104.8,96,"",0.67,1.57,2105,"","",2224.6,2228.7,2219.6,2195.4,2085.3,2016,2020.2,2049.9,106.8,"","",1775.2,1686.9,1762.6,1590,1501.9,2016,1646.5,1635.8,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P49354","Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha OS=Homo sapiens OX=9606 GN=FNTA PE=1 SV=1",0,27.416,18,8,10,8,379,44.4,5.08,28.61,8,"cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus","cytoplasm;cytosol;membrane","catalytic activity;protein binding","Pf01239","2339","ENSG00000168522.12","FNTA","8","Terpenoid backbone biosynthesis","Signaling by GPCR; Apoptotic cleavage of cellular proteins; Inactivation, recovery and regulation of the phototransduction cascade","",10,0,1.082,0.11,0.280248299013706,0.901260751937089,92.3,107.9,99.8,"",5.5,2.68,628.7,"","",732.7,778.4,737.4,680.2,683.3,713.5,674.1,675.6,31.9,"","",584.7,589.2,585.6,492.6,492.1,713.5,549.4,539.1,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q7L8W6","Diphthine--ammonia ligase OS=Homo sapiens OX=9606 GN=DPH6 PE=1 SV=3",0,13.391,18,5,5,5,267,30.3,5.4,14.11,5,"metabolic process;regulation of biological process","cytosol;nucleus","catalytic activity;nucleotide binding","Pf01902","89978","ENSG00000134146.11","ATPBD4; DPH6","15","","Synthesis of diphthamide-EEF2","",4,0,0.916,-0.13,0.282128779985045,0.902003215632576,89.6,100.6,109.8,"",3.7,2.55,662.3,"","",737.3,749.1,754.3,694.5,813.9,811.5,810.8,771.2,33.6,"","",588.4,567,599,503,586.2,811.5,660.8,615.4,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","O75116","Rho-associated protein kinase 2 OS=Homo sapiens OX=9606 GN=ROCK2 PE=1 SV=4",0,257.288,39,63,85,57,1388,160.8,6.02,230.51,63,"cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus","cytoplasm;cytoskeleton;cytosol;membrane;nucleus","catalytic activity;metal ion binding;motor activity;nucleotide binding;protein binding;RNA binding;structural molecule activity","Pf00069, Pf00130, Pf01576, Pf01636, Pf02185, Pf02463, Pf04111, Pf04156, Pf05557, Pf05622, Pf05667, Pf06160, Pf07714, Pf07888, Pf08912, Pf09726, Pf09731, Pf11559, Pf12128, Pf12718, Pf12795, Pf13166, Pf14531, Pf14915","9475","ENSG00000134318.13","ROCK2","2","cAMP signaling pathway; Regulation of actin cytoskeleton; Wnt signaling pathway; Vascular smooth muscle contraction; Shigellosis; Chemokine signaling pathway; Proteoglycans in cancer; Oxytocin signaling pathway; Leukocyte transendothelial migration; Pathogenic Escherichia coli infection; Salmonella infection; Platelet activation; Focal adhesion; Axon guidance; Pathways in cancer; Sphingolipid signaling pathway; cGMP-PKG signaling pathway","EPHA-mediated growth cone collapse; G alpha (12/13) signalling events; EPHB-mediated forward signaling; RHO GTPases Activate ROCKs; Sema4D induced cell migration and growth-cone collapse; VEGFA-VEGFR2 Pathway","Androgen receptor signaling pathway; MicroRNAs in cardiomyocyte hypertrophy; Integrin-mediated Cell Adhesion; Leptin signaling pathway; Pathogenic Escherichia coli infection; Spinal Cord Injury; Focal Adhesion; Association Between Physico-Chemical Features and Toxicity Associated Pathways; VEGFA-VEGFR2 Signaling Pathway; Chemokine signaling pathway; Regulation of Actin Cytoskeleton; G13 Signaling Pathway",47,3,0.936,-0.09,0.285643474596058,0.906358159967137,99.9,96.8,103.3,"",2.26,1.29,10812.8,"","",10343.1,10662.7,10156.7,10605.3,11186.5,10899.4,11180.8,11193.2,548.6,"","",8253.8,8070.6,8065.4,7680.8,8056.8,10899.4,9112.5,8931.9,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q13217","DnaJ homolog subfamily C member 3 OS=Homo sapiens OX=9606 GN=DNAJC3 PE=1 SV=1",0,62.632,35,16,20,16,504,57.5,6.15,58.06,16,"defense response;metabolic process;regulation of biological process;response to stimulus;transport","cytoplasm;cytosol;endoplasmic reticulum;extracellular;membrane;organelle lumen","enzyme regulator activity;protein binding","Pf00226, Pf00515, Pf12569, Pf13371, Pf13414, Pf13432, Pf14559","5611","ENSG00000102580.14","DNAJC3","13","Protein processing in endoplasmic reticulum; Influenza A","Post-translational protein phosphorylation; Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs); Viral mRNA Translation; Neutrophil degranulation; XBP1(S) activates chaperone genes","Photodynamic therapy-induced unfolded protein response",19,0,1.081,0.11,0.287436823417601,0.906795439502517,103.2,102.2,94.6,"",2.19,3.27,3029.4,"","",3044.8,3023.9,2976,2897.4,2832.3,2820.3,2731.9,2638.2,153.7,"","",2429.8,2288.8,2363.2,2098.4,2039.9,2820.3,2226.5,2105.2,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q9NPI8","Fanconi anemia group F protein OS=Homo sapiens OX=9606 GN=FANCF PE=1 SV=1",0.005,2.769,2,1,1,1,374,42.2,8.94,2.73,1,"metabolic process;response to stimulus","nucleus","catalytic activity;protein binding","Pf11107","2188","ENSG00000183161.4","FANCF","11","Fanconi anemia pathway","Fanconi Anemia Pathway","",3,0,1.113,0.15,0.289945120272557,0.909261735299361,97,106.9,96.1,"",7.97,2.62,59.1,"","",69.5,68.6,58.9,61.9,58.2,60.1,56.4,58.9,3,"","",55.5,51.9,46.8,44.8,41.9,60.1,46,47,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P11166","Solute carrier family 2, facilitated glucose transporter member 1 OS=Homo sapiens OX=9606 GN=SLC2A1 PE=1 SV=2",0,15.87,6,4,5,4,492,54,8.72,13.16,4,"cell communication;cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus;transport","cytoplasm;cytoskeleton;cytosol;membrane;nucleus","protein binding;transporter activity","Pf00083, Pf07690, Pf13347","6513","ENSG00000117394.20","SLC2A1","1","Adipocytokine signaling pathway; Insulin secretion; Central carbon metabolism in cancer; HTLV-I infection; Pathways in cancer; Renal cell carcinoma; Thyroid hormone signaling pathway; Bile secretion; Insulin resistance; HIF-1 signaling pathway; Glucagon signaling pathway","Lactose synthesis; Defective SLC2A1 causes GLUT1 deficiency syndrome 1 (GLUT1DS1); Cellular hexose transport; Regulation of insulin secretion; Vitamin C (ascorbate) metabolism","Cori Cycle; NRF2 pathway; Photodynamic therapy-induced HIF-1 survival signaling; Angiopoietin Like Protein 8 Regulatory Pathway; Focal Adhesion-PI3K-Akt-mTOR-signaling pathway; Insulin Signaling; Glycolysis and Gluconeogenesis",33,0,0.929,-0.11,0.29236112827093,0.910931632519606,103,94.9,102.2,"",10.46,8.46,1220,"","",1144.4,1146.5,1103.3,909.9,1034,1190.1,1256.5,1230.5,61.9,"","",913.2,867.8,876.1,659,744.7,1190.1,1024.1,981.9,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q6RFH5","WD repeat-containing protein 74 OS=Homo sapiens OX=9606 GN=WDR74 PE=1 SV=1",0,116.268,52,18,28,1,385,42.4,8.32,102.54,18,"","nucleus","protein binding","Pf00400","54663","ENSG00000133316.15","WDR74","11","","","",0,17,0.934,-0.1,0.29523870947749,0.914403301002315,97.3,97.9,104.8,"",0.74,3.24,3145.7,"","",3165,3211.3,3166.1,3162.2,3196.4,3367.4,3410.5,3438.2,159.6,"","",2525.7,2430.6,2514.2,2290.2,2302.1,3367.4,2779.6,2743.6,"Not Found","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q8NC54","Keratinocyte-associated transmembrane protein 2 OS=Homo sapiens OX=9606 GN=KCT2 PE=1 SV=2",0,7.967,8,2,2,2,265,29.2,5.08,3.25,2,"","membrane","","","56951","ENSG00000113583.7","C5orf15","5","","","",0,0,1.103,0.14,0.297450349626248,0.914403301002315,114.1,97.5,88.4,"",15.27,14.29,181.3,"","",177.3,149.2,160.9,122.1,115.8,147.1,163.1,134.2,9.2,"","",141.5,112.9,127.8,88.4,83.4,147.1,132.9,107.1,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q14691","DNA replication complex GINS protein PSF1 OS=Homo sapiens OX=9606 GN=GINS1 PE=1 SV=1",0,44.163,57,10,13,10,196,23,7.39,37.48,10,"cell proliferation;metabolic process","cytoplasm;nucleus","catalytic activity","Pf05916","9837","ENSG00000101003.9","GINS1","20","","Unwinding of DNA","",7,0,0.932,-0.1,0.300792402993828,0.916994488705437,90.5,101.1,108.4,"",3.95,4.2,1704.9,"","",1896.6,1862.1,1911,2036.3,2023.2,1893.6,2060.5,2083.3,86.5,"","",1513.5,1409.4,1517.5,1474.8,1457.2,1893.6,1679.3,1662.4,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q9NPD3","Exosome complex component RRP41 OS=Homo sapiens OX=9606 GN=EXOSC4 PE=1 SV=3",0,41.471,30,7,12,7,245,26.4,6.52,49.36,7,"defense response;metabolic process;regulation of biological process;response to stimulus","cytoplasm;cytoskeleton;cytosol;nucleus","catalytic activity;protein binding;RNA binding","Pf01138, Pf03725","54512","ENSG00000178896.8","EXOSC4","8","RNA degradation","Major pathway of rRNA processing in the nucleolus and cytosol; mRNA decay by 3' to 5' exoribonuclease; ATF4 activates genes; Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA; Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA; KSRP (KHSRP) binds and destabilizes mRNA","",15,0,0.931,-0.1,0.300203102083804,0.916994488705437,89.3,101.6,109.2,"",6.59,2.25,1131.3,"","",1319,1276.7,1298.7,1135.9,1374.8,1350.7,1424.9,1392.8,57.4,"","",1052.6,966.3,1031.3,822.7,990.2,1350.7,1161.3,1111.4,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P21860","Receptor tyrosine-protein kinase erbB-3 OS=Homo sapiens OX=9606 GN=ERBB3 PE=1 SV=1",0,8.486,2,3,3,3,1342,148,6.55,7.35,3,"cell death;cell differentiation;metabolic process;regulation of biological process;response to stimulus","extracellular;membrane","catalytic activity;enzyme regulator activity;nucleotide binding;protein binding;receptor activity;signal transducer activity","Pf00069, Pf00757, Pf01030, Pf07714, Pf14843","2065","ENSG00000065361.14","ERBB3","12","Endocytosis; EGFR tyrosine kinase inhibitor resistance; Calcium signaling pathway; MicroRNAs in cancer; Proteoglycans in cancer; ErbB signaling pathway","SHC1 events in ERBB2 signaling; Signaling by ERBB4; PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling; GRB7 events in ERBB2 signaling; Downregulation of ERBB2:ERBB3 signaling; ERBB2 Regulates Cell Motility; ERBB2 Activates PTK6 Signaling; PI3K events in ERBB2 signaling; Constitutive Signaling by Aberrant PI3K in Cancer; RAF/MAP kinase cascade; Interleukin-20 family signaling","Heart Development; Signaling Pathways in Glioblastoma; Apoptosis-related network due to altered Notch3 in ovarian cancer; ErbB Signaling Pathway",38,0,1.099,0.14,0.303918451949956,0.920232722095346,109,100,91,"",7.25,11.09,153.7,"","",139.8,128.2,153,142.5,155.1,129.6,121.8,127.2,7.8,"","",111.6,97,121.5,103.2,111.7,129.6,99.3,101.5,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q7Z494","Nephrocystin-3 OS=Homo sapiens OX=9606 GN=NPHP3 PE=1 SV=1",0,7.546,2,3,3,3,1330,150.8,6.76,7.13,3,"cell organization and biogenesis;cellular component movement;regulation of biological process;response to stimulus","cytosol","protein binding","Pf00515, Pf03938, Pf13176, Pf13374, Pf13414, Pf13424, Pf13432","27031","ENSG00000113971.19","NPHP3","3","","Trafficking of myristoylated proteins to the cilium","Wnt Signaling in Kidney Disease",5,0,1.141,0.19,0.305041516590198,0.920935411481519,"",159.9,140.1,"",23.19,18.11,"","","",29.9,28.9,34,18.8,19.3,24.7,30.2,26.9,"","","",23.9,21.9,27,13.6,13.9,24.7,24.6,21.5,"Not Found","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q9BYX2","TBC1 domain family member 2A OS=Homo sapiens OX=9606 GN=TBC1D2 PE=1 SV=3",0,44.18,16,16,17,16,928,105.3,6.58,48.72,16,"regulation of biological process;transport","cytoplasm;cytosol;nucleus","enzyme regulator activity;protein binding","Pf00169, Pf00566, Pf15413","55357","ENSG00000095383.19","TBC1D2","9","","TBC/RABGAPs","",4,0,1.076,0.11,0.308816639660905,0.926008682317062,100.8,103.2,95.9,"",9.73,3.29,1486.1,"","",1443.9,1604,1405.7,1731.6,1368.3,1404,1424.3,1480.1,75.4,"","",1152.2,1214.1,1116.3,1254.1,985.5,1404,1160.8,1181.1,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q8TAE8","Growth arrest and DNA damage-inducible proteins-interacting protein 1 OS=Homo sapiens OX=9606 GN=GADD45GIP1 PE=1 SV=1",0,44.2,36,6,10,6,222,25.4,10.02,36,6,"cell organization and biogenesis;metabolic process;regulation of biological process","mitochondrion;nucleus;organelle lumen;ribosome","protein binding","Pf10147","90480","ENSG00000179271.2","GADD45GIP1","19","","Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination","",6,0,1.088,0.12,0.312122874756089,0.926873918211021,165.9,69.9,64.2,93.38,4.92,3.44,2122.8,10374.5,"",1946.4,2009.2,2045,1825.9,1757.2,1822.5,1811.3,1909.1,107.7,2.9,"",1553.2,1520.8,1623.9,1322.4,1265.6,1822.5,1476.2,1523.4,"High","High","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"Low","Master Protein","Q8NGR3","Olfactory receptor 1K1 OS=Homo sapiens OX=9606 GN=OR1K1 PE=2 SV=1",0.083,1.123,2,1,1,1,316,34.2,7.93,2.26,1,"regulation of biological process;response to stimulus","membrane","receptor activity;signal transducer activity","Pf00001, Pf13853","392392","ENSG00000165204.3","OR1K1","9","Olfactory transduction","Olfactory Signaling Pathway; GPCR downstream signalling","",5,0,1.096,0.13,0.312357850446994,0.926873918211021,85.7,112.1,102.2,"",3.02,6.8,110.4,"","",145.1,146,136.5,143.6,134.5,130.2,115.6,133.2,5.6,"","",115.8,110.5,108.4,104,96.9,130.2,94.2,106.3,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q8N357","Solute carrier family 35 member F6 OS=Homo sapiens OX=9606 GN=SLC35F6 PE=1 SV=1",0,14.254,7,4,6,4,371,40.2,6.93,17.84,4,"regulation of biological process;transport","cytosol;membrane;mitochondrion;vacuole","protein binding;transporter activity","Pf00892, Pf04142","54978","ENSG00000213699.8","C2orf18; SLC35F6","2","","","",0,0,0.924,-0.11,0.315062097507608,0.929320746135483,78.9,106.2,114.9,"",5.6,8.4,402.1,"","",542.7,542.1,540.2,482.7,494.3,579.4,593.9,591.6,20.4,"","",433.1,410.3,429,349.6,356,579.4,484,472.1,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q53T94","TATA box-binding protein-associated factor RNA polymerase I subunit B OS=Homo sapiens OX=9606 GN=TAF1B PE=1 SV=1",0,10.083,8,4,4,4,588,68.8,8.02,11.4,4,"cell organization and biogenesis;metabolic process;regulation of biological process","nucleus","DNA binding;metal ion binding;protein binding","Pf11781","9014","ENSG00000115750.16","TAF1B","2","","SIRT1 negatively regulates rRNA expression; RNA Polymerase I Transcription Termination; RNA Polymerase I Chain Elongation; NoRC negatively regulates rRNA expression; RNA Polymerase I Promoter Escape; B-WICH complex positively regulates rRNA expression; RNA Polymerase I Transcription Initiation","",13,0,0.911,-0.13,0.317797981681452,0.929885722013816,85.9,102.1,112,"",8.26,3.12,264.1,"","",306.9,323.2,320.5,268.6,338.1,332.5,350.4,355.8,13.4,"","",244.9,244.6,254.5,194.5,243.5,332.5,285.6,283.9,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q5VTU8","ATP synthase subunit epsilon-like protein, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1EP2 PE=1 SV=1",0,8.391,29,2,6,2,51,5.8,10.14,13.28,2,"metabolic process;transport","membrane;mitochondrion","catalytic activity;transporter activity","Pf04627","432369","ENSG00000180389.6","ATP5EP2","13","","","",0,0,0.921,-0.12,0.320445555153752,0.931710128239307,93.2,99.1,107.6,"",25.77,7.69,678,"","",676.3,649.2,768.2,1096,818.4,741.1,869.9,748.8,34.4,"","",539.7,491.4,610,793.8,589.4,741.1,709,597.5,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P50579-2","Isoform 2 of Methionine aminopeptidase 2 OS=Homo sapiens OX=9606 GN=METAP2",0,84.888,36,14,32,2,455,50.5,5.35,87.96,14,"metabolic process;regulation of biological process","cytoplasm;cytosol;membrane","catalytic activity;metal ion binding;RNA binding","Pf00557","10988","ENSG00000111142.13","METAP2","12","","","",0,0,1.098,0.13,0.324078048255929,0.935961188907948,87.2,111.4,101.4,"",10.02,10.92,63.1,"","",77.7,84.2,83.5,67.2,71.2,77.2,60,75.6,3.2,"","",62,63.7,66.3,48.7,51.3,77.2,48.9,60.3,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","O00141","Serine/threonine-protein kinase Sgk1 OS=Homo sapiens OX=9606 GN=SGK1 PE=1 SV=2",0,11.609,8,3,3,3,431,48.9,8.54,10.72,3,"cell death;cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus;transport","cytoplasm;cytosol;endoplasmic reticulum;membrane;mitochondrion;nucleus","catalytic activity;nucleotide binding;protein binding","Pf00069, Pf00433, Pf07714, Pf14531","6446","ENSG00000118515.11","SGK1","6","Aldosterone-regulated sodium reabsorption; FoxO signaling pathway; PI3K-Akt signaling pathway; mTOR signaling pathway","Regulation of TP53 Degradation; Stimuli-sensing channels","Follicle Stimulating Hormone (FSH) signaling pathway; Mecp2 and Associated Rett Syndrome; Insulin Signaling",17,0,1.092,0.13,0.326604118589307,0.937563404032691,82.8,113.4,103.8,"",7.19,10.7,291.7,"","",393.2,426.9,405.7,358.9,408.9,386.5,346.1,321.9,14.8,"","",313.8,323.1,322.2,259.9,294.5,386.5,282.1,256.9,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q9P2R3","Rabankyrin-5 OS=Homo sapiens OX=9606 GN=ANKFY1 PE=1 SV=2",0,88.018,21,19,23,19,1169,128.3,6.1,77.58,19,"cell organization and biogenesis;regulation of biological process;transport","cytoplasm;cytosol;endosome;membrane","metal ion binding;protein binding","Pf00023, Pf00651, Pf01363, Pf07707, Pf12796, Pf13606, Pf13637, Pf13857","51479","ENSG00000185722.16","ANKFY1","17","","","",0,0,1.071,0.1,0.329737485388631,0.938995296685113,99.2,103.8,97,"",2.1,1.51,3112.2,"","",3253.1,3261.3,3312.2,3149.5,3062.1,2974.4,3023.1,3076.5,157.9,"","",2596,2468.5,2630.2,2281,2205.4,2974.4,2463.9,2455,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q15773","Myeloid leukemia factor 2 OS=Homo sapiens OX=9606 GN=MLF2 PE=1 SV=1",0,13.37,17,5,6,5,248,28.1,6.9,13.06,5,"defense response;response to stimulus","cytoplasm;membrane;nucleus","protein binding","Pf10248","8079","ENSG00000089693.10","MLF2","12","","","",0,0,0.895,-0.16,0.329768063957163,0.938995296685113,55.4,115.5,129.1,"",31.71,5.34,71,"","",133.6,144.5,151.7,250.1,169.7,161.4,156.7,176.7,3.6,"","",106.6,109.4,120.5,181.1,122.2,161.4,127.7,141,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P54278","Mismatch repair endonuclease PMS2 OS=Homo sapiens OX=9606 GN=PMS2 PE=1 SV=2",0,91.979,25,18,24,16,862,95.7,6.86,71.61,18,"metabolic process;response to stimulus","cytoskeleton;cytosol;membrane;nucleus","catalytic activity;DNA binding;nucleotide binding;protein binding","Pf01119, Pf02518, Pf08676, Pf13589","5395; 107984056","ENSG00000122512.14","PMS2; LOC107984056","7","Fanconi anemia pathway; Mismatch repair","Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta); Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha); TP53 Regulates Transcription of DNA Repair Genes; Defective Mismatch Repair Associated With MLH1; Defective Mismatch Repair Associated With PMS2","",15,2,0.941,-0.09,0.333181388549191,0.94011503838021,103.4,95.3,101.3,"",1.29,2.45,2440.1,"","",2293.7,2226.1,2257.5,2241.4,2394.1,2290.2,2384.5,2425,123.8,"","",1830.4,1684.9,1792.7,1623.3,1724.3,2290.2,1943.4,1935.1,"High","Not Found","High","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q7Z309-3","Isoform 3 of Protein FAM122B OS=Homo sapiens OX=9606 GN=FAM122B",0,31.673,47,7,7,5,266,29.1,8.16,24.3,7,"","","","","159090","ENSG00000156504.16","FAM122B","X","","","",0,2,1.094,0.13,0.335742460280975,0.941975886223998,77.2,116.4,106.4,"",10.93,13.1,216.8,"","",327.1,308.5,326.5,392.7,367.4,292.3,273.9,305.1,11,"","",261,233.5,259.3,284.4,264.6,292.3,223.2,243.5,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q7Z6Z7","E3 ubiquitin-protein ligase HUWE1 OS=Homo sapiens OX=9606 GN=HUWE1 PE=1 SV=3",0,649.815,27,111,190,1,4374,481.6,5.22,586.77,111,"cell differentiation;cell organization and biogenesis;metabolic process;response to stimulus;transport","cytoplasm;cytosol;extracellular;membrane;nucleus;organelle lumen","catalytic activity;DNA binding;protein binding;RNA binding","Pf00632, Pf02825, Pf06012, Pf06025, Pf14377","10075","ENSG00000086758.15","HUWE1","X","Ubiquitin mediated proteolysis","Neutrophil degranulation; Antigen processing: Ubiquitination & Proteasome degradation","",7,0,1.099,0.14,0.340590866153842,0.944228347266852,122.1,93.1,84.7,"",12.83,11.69,82.8,"","",63.7,62.9,63.3,48.1,52.1,60.7,54.4,67.3,4.2,"","",50.8,47.6,50.3,34.8,37.5,60.7,44.3,53.7,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q86WC4","Osteopetrosis-associated transmembrane protein 1 OS=Homo sapiens OX=9606 GN=OSTM1 PE=1 SV=1",0,15.603,12,3,4,3,334,37.2,6.01,11.95,3,"cell differentiation;transport","cytosol;membrane;vacuole","","Pf09777","28962","ENSG00000081087.14","OSTM1","6","","Stimuli-sensing channels","",3,0,1.09,0.12,0.340955431554964,0.944228347266852,72.8,118.5,108.7,"",7.45,1.15,266.1,"","",453.8,422.8,444.2,382.3,391,400.6,400,394.9,13.5,"","",362.1,320,352.7,276.9,281.6,400.6,326,315.1,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","O95298","NADH dehydrogenase [ubiquinone] 1 subunit C2 OS=Homo sapiens OX=9606 GN=NDUFC2 PE=1 SV=1",0,18.619,17,4,6,4,119,14.2,8.98,17.17,4,"cell organization and biogenesis;metabolic process;transport","cytoplasm;membrane;mitochondrion","catalytic activity","Pf06374","4718; 100532726","ENSG00000151366.12","NDUFC2; NDUFC2-KCTD14","11","Huntington's disease; Metabolic pathways; Alzheimer's disease; Non-alcoholic fatty liver disease (NAFLD); Parkinson's disease; Oxidative phosphorylation","Neutrophil degranulation; Complex I biogenesis","Electron Transport Chain; Oxidative phosphorylation",16,0,1.081,0.11,0.342293601439225,0.945039480660841,117.3,94.9,87.8,"",4.24,3.55,2377,"","",1935.5,1910.6,1966.6,1783.2,1795.8,1762.9,1667.8,1803.6,120.6,"","",1544.5,1446.1,1561.7,1291.5,1293.4,1762.9,1359.3,1439.2,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P02538","Keratin, type II cytoskeletal 6A OS=Homo sapiens OX=9606 GN=KRT6A PE=1 SV=3",0,78.719,21,16,84,4,564,60,8,229.65,16,"cell death;cell differentiation;cell organization and biogenesis;defense response;metabolic process;regulation of biological process;response to stimulus","cytosol;membrane;nucleus","protein binding;structural molecule activity","Pf00038, Pf04111, Pf13166","3853","ENSG00000205420.10","KRT6A","12","","Formation of the cornified envelope","Ectoderm Differentiation",4,0,1.09,0.12,0.345475824607502,0.946607783839391,88.9,110.1,101,"",5.99,7.7,112.3,"","",141.1,137.9,123.8,140.4,124.1,124.2,131.3,145.6,5.7,"","",112.6,104.4,98.3,101.7,89.4,124.2,107,116.2,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","O00273-2","Isoform DFF35 of DNA fragmentation factor subunit alpha OS=Homo sapiens OX=9606 GN=DFFA",0,46.222,42,10,13,1,268,29.4,4.61,38.24,10,"cell death;metabolic process;regulation of biological process","cytosol;membrane;nucleus","enzyme regulator activity;protein binding","Pf02017, Pf09033","1676","ENSG00000160049.11","DFFA","1","","","Apoptosis; Fas Ligand (FasL) pathway and Stress induction of Heat Shock Proteins (HSP) regulation",2,0,1.097,0.13,0.347634634626788,0.947355789760608,92.1,108.8,99.1,"",7.29,7.66,55.2,"","",71.9,60.5,66.4,64.1,59.6,59.3,65,53.9,2.8,"","",57.4,45.8,52.7,46.4,42.9,59.3,53,43,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P00751","Complement factor B OS=Homo sapiens OX=9606 GN=CFB PE=1 SV=2",0,37.233,13,7,8,7,764,85.5,7.06,27.25,7,"defense response;metabolic process;regulation of biological process;response to stimulus","extracellular;membrane","catalytic activity;protein binding","Pf00084, Pf00089, Pf00092, Pf13519","629","ENSG00000243649.8; ENSG00000242335.8; ENSG00000243570.9; ENSG00000239754.9; ENSG00000241534.9","CFB","6; CHR_HSCHR6_MHC_SSTO_CTG1; CHR_HSCHR6_MHC_MCF_CTG1; CHR_HSCHR6_MHC_COX_CTG1; CHR_HSCHR6_MHC_DBB_CTG1","Complement and coagulation cascades; Staphylococcus aureus infection","Alternative complement activation; Regulation of Complement cascade; Activation of C3 and C5","Complement Activation; Complement and Coagulation Cascades",11,0,1.091,0.12,0.350470554239851,0.948514130320107,92.3,108.3,99.3,"",5.78,10.13,96.6,"","",115.3,115.7,111.3,101.9,96.4,112,94.8,115.5,4.9,"","",92,87.6,88.4,73.8,69.4,112,77.3,92.2,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q05519","Serine/arginine-rich splicing factor 11 OS=Homo sapiens OX=9606 GN=SRSF11 PE=1 SV=1",0,59.54,21,9,14,9,484,53.5,10.52,48.87,9,"metabolic process;transport","nucleus","protein binding;RNA binding","Pf00076, Pf13893, Pf14259","9295","ENSG00000116754.13","SRSF11","1","","Cleavage of Growing Transcript in the Termination Region ; Transport of Mature mRNA derived from an Intron-Containing Transcript; mRNA 3'-end processing; mRNA Splicing - Major Pathway","",11,0,0.945,-0.08,0.352403995139092,0.949460754488374,107.9,93.3,98.8,"",6.35,2.58,2881.6,"","",2500.1,2424.8,2484.8,2787.2,2587,2566.4,2689,2697.5,146.2,"","",1995.1,1835.3,1973.2,2018.6,1863.2,2566.4,2191.6,2152.5,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q7L3B6","Hsp90 co-chaperone Cdc37-like 1 OS=Homo sapiens OX=9606 GN=CDC37L1 PE=1 SV=1",0,30.273,18,5,6,5,337,38.8,5.34,24.99,5,"metabolic process;regulation of biological process;transport","cytoplasm;cytosol;extracellular;organelle lumen","protein binding","Pf08565","55664","ENSG00000106993.11","CDC37L1","9","","Platelet degranulation","",4,0,0.911,-0.14,0.35412363447976,0.949603788953109,97,96.7,106.2,"",13,14.37,167.5,"","",156.5,153.4,178.3,201.7,172.7,145.5,194.8,202.9,8.5,"","",124.9,116.1,141.6,146.1,124.4,145.5,158.8,161.9,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q9NP64","Nucleolar protein of 40 kDa OS=Homo sapiens OX=9606 GN=ZCCHC17 PE=1 SV=1",0,22.09,17,4,8,4,241,27.6,9.7,26.71,4,"","nucleus","metal ion binding;protein binding;RNA binding","Pf00575","51538","ENSG00000121766.15","ZCCHC17","1","","","",0,0,1.072,0.1,0.357832441712974,0.951506052764912,104.5,101.1,94.4,"",9.34,7.31,770.7,"","",791.2,731.3,761.5,634.2,648.5,669.6,760.8,724.3,39.1,"","",631.4,553.5,604.7,459.3,467.1,669.6,620.1,578,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q68E01-2","Isoform 2 of Integrator complex subunit 3 OS=Homo sapiens OX=9606 GN=INTS3",0,57.434,17,15,20,15,1042,117.9,5.8,61.41,15,"metabolic process;regulation of biological process;response to stimulus","cytoplasm;nucleus","protein binding","Pf10189","65123","ENSG00000143624.13; ENSG00000262826.5","INTS3","1; CHR_HSCHR1_1_CTG31","","","",0,0,0.94,-0.09,0.359327011747423,0.951627577356399,233.6,32.2,34.2,107.17,2.33,1.46,1267.3,9659,29211.5,1322.9,1338.2,1299.6,1373.7,1423.9,1408,1400.7,1447.7,64.3,2.7,3.7,1055.7,1012.9,1032,994.9,1025.5,1408,1141.6,1155.2,"High","High","High","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q9NRH1","Protein YAE1 homolog OS=Homo sapiens OX=9606 GN=YAE1 PE=1 SV=1",1E-3,5.179,9,2,2,2,226,25.3,5.59,6.23,2,"metabolic process","","","Pf09811","57002","ENSG00000241127.7","YAE1D1","7","","","",0,0,0.93,-0.1,0.359141082342125,0.951627577356399,108.6,92.2,99.2,"",3.84,3.65,522.3,"","",427.4,468.6,446.2,441.2,464.3,465.2,499.3,489.2,26.5,"","",341.1,354.7,354.3,319.5,334.4,465.2,406.9,390.4,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","O14744","Protein arginine N-methyltransferase 5 OS=Homo sapiens OX=9606 GN=PRMT5 PE=1 SV=4",0,91.076,27,16,26,16,637,72.6,6.29,77.59,16,"cell organization and biogenesis;cell proliferation;metabolic process;regulation of biological process","cytoplasm;cytosol;Golgi;nucleus","catalytic activity;DNA binding;nucleotide binding;protein binding","Pf02475, Pf05185","10419","ENSG00000100462.15","PRMT5","14","RNA transport","snRNP Assembly; Regulation of TP53 Activity through Methylation; RMTs methylate histone arginines","",13,0,1.057,0.08,0.369733971316258,0.953020473808368,102.2,101.7,96.1,"",8.12,4.77,5254.6,"","",5340.1,5237.1,5215.9,4449.6,4776.7,4973.9,5335.5,4911.7,266.6,"","",4261.4,3964,4141.9,3222.6,3440.3,4973.9,4348.5,3919.4,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q9NVH1","DnaJ homolog subfamily C member 11 OS=Homo sapiens OX=9606 GN=DNAJC11 PE=1 SV=2",0,58.16,27,14,18,14,559,63.2,8.4,51.05,14,"cell organization and biogenesis","membrane;mitochondrion","protein binding","Pf00226, Pf11875","55735","ENSG00000007923.15","DNAJC11","1","","Cristae formation","",3,0,1.07,0.1,0.365081315057235,0.953020473808368,159.8,72.4,67.7,90.64,2.84,3.41,3053.1,13951.9,"",2973,2982.6,2943.2,2803.6,2803.8,2832.7,2622.8,2728,154.9,3.9,"",2372.5,2257.5,2337.2,2030.5,2019.4,2832.7,2137.6,2176.9,"High","High","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q9Y4E6","WD repeat-containing protein 7 OS=Homo sapiens OX=9606 GN=WDR7 PE=1 SV=2",0,32.319,6,10,10,10,1490,163.7,6.92,24.1,10,"cell differentiation","cytoplasm","protein binding","Pf00400","23335","ENSG00000091157.13","WDR7","18","","","",0,0,1.072,0.1,0.36612566473283,0.953020473808368,100.9,103,96.1,"",4.33,2.73,776.6,"","",739.5,821.1,794.4,790.2,735.2,749.7,743.2,704.4,39.4,"","",590.1,621.5,630.8,572.3,529.5,749.7,605.7,562.1,"High","High","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q9NWW5","Ceroid-lipofuscinosis neuronal protein 6 OS=Homo sapiens OX=9606 GN=CLN6 PE=1 SV=1",0,18.068,7,2,2,2,311,35.9,8.87,8.2,2,"cell organization and biogenesis;cellular homeostasis;metabolic process;regulation of biological process","endoplasmic reticulum;membrane;organelle lumen","protein binding","Pf15156","54982","ENSG00000128973.12","CLN6","15","","","",0,0,1.085,0.12,0.369991422246246,0.953020473808368,109.6,99.1,91.3,"",8.85,5.15,104.5,"","",111.8,94.1,94.2,94.7,81.9,86.7,92.9,87.3,5.3,"","",89.2,71.2,74.8,68.6,59,86.7,75.7,69.7,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","O95379","Tumor necrosis factor alpha-induced protein 8 OS=Homo sapiens OX=9606 GN=TNFAIP8 PE=1 SV=1",0,10.239,15,3,3,3,198,23,7.93,8.41,3,"cell death;regulation of biological process","cytoplasm","enzyme regulator activity;protein binding","Pf05527","25816","ENSG00000145779.7","TNFAIP8","5","","PI Metabolism","",4,0,0.916,-0.13,0.37459432594616,0.953020473808368,97,97.1,105.9,"",2.92,4.34,256.2,"","",260.8,251.9,263.4,247.4,288.5,262.6,273.4,286.2,13,"","",208.1,190.7,209.2,179.2,207.8,262.6,222.8,228.4,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P50454","Serpin H1 OS=Homo sapiens OX=9606 GN=SERPINH1 PE=1 SV=2",0,146.848,49,20,56,20,418,46.4,8.69,175.95,20,"cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus","cytoplasm;endoplasmic reticulum;membrane;organelle lumen","enzyme regulator activity;protein binding;RNA binding","Pf00079","871","ENSG00000149257.13","SERPINH1","11","","Collagen biosynthesis and modifying enzymes","Endochondral Ossification",4,0,1.056,0.08,0.37542015255989,0.953666114459922,119.8,92.5,87.6,44.1,5.79,6.92,9094.1,11447.7,20527,8750.3,8923.9,9114.3,7968.8,8586.2,9028.2,8162.7,7675.7,461.4,3.2,2.6,6982.8,6754.5,7237.6,5771.3,6184,9028.2,6652.7,6125,"High","High","High","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q15363","Transmembrane emp24 domain-containing protein 2 OS=Homo sapiens OX=9606 GN=TMED2 PE=1 SV=1",0,35.132,22,6,11,6,201,22.7,5.17,30.16,6,"cell organization and biogenesis;regulation of biological process;transport","endoplasmic reticulum;Golgi;membrane","protein binding","Pf01105","10959","ENSG00000086598.10","TMED2","12","","COPI-dependent Golgi-to-ER retrograde traffic; Cargo concentration in the ER; Pre-NOTCH Processing in Golgi; COPII (Coat Protein 2) Mediated Vesicle Transport; COPI-mediated anterograde transport","",17,0,1.08,0.11,0.376496807607219,0.954315309325106,161.2,72.1,66.8,82.35,4.31,8.7,2266.6,8585.8,"",2014.5,1872.6,1932.5,2063.5,1699.6,1682.3,1964.8,1967.6,115,2.4,"",1607.6,1417.4,1534.6,1494.5,1224.1,1682.3,1601.3,1570.1,"High","High","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q8IUW5","RELT-like protein 1 OS=Homo sapiens OX=9606 GN=RELL1 PE=1 SV=1",0.004,3.08,3,1,1,1,271,29.3,8.34,2.93,1,"","cytoskeleton;membrane","","Pf12606","768211","ENSG00000181826.9","RELL1","4","","","",0,0,1.079,0.11,0.377726392036541,0.955379535972033,95.9,105.9,98.2,"",9.81,16.51,114.3,"","",127.4,125,114.6,144.8,97.2,118.7,115.3,144.9,5.8,"","",101.7,94.6,91,104.9,70,118.7,94,115.6,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P09622","Dihydrolipoyl dehydrogenase, mitochondrial OS=Homo sapiens OX=9606 GN=DLD PE=1 SV=2",0,116.5,29,16,34,16,509,54.1,7.85,96.94,16,"cellular homeostasis;metabolic process;regulation of biological process","mitochondrion;organelle lumen","catalytic activity;nucleotide binding;protein binding","Pf00070, Pf00890, Pf01134, Pf02852, Pf03486, Pf07992, Pf12831, Pf13450","1738","ENSG00000091140.13","DLD","7","Glycine, serine and threonine metabolism; Propanoate metabolism; Valine, leucine and isoleucine degradation; Glycolysis / Gluconeogenesis; Carbon metabolism; Metabolic pathways; Glyoxylate and dicarboxylate metabolism; Pyruvate metabolism; Citrate cycle (TCA cycle)","Glycine degradation; Regulation of pyruvate dehydrogenase (PDH) complex; Lysine catabolism; Signaling by Retinoic Acid; Branched-chain amino acid catabolism; Citric acid cycle (TCA cycle)","Fatty Acid Beta Oxidation; TCA Cycle and Deficiency of Pyruvate Dehydrogenase complex (PDHc); Amino Acid metabolism; Glycolysis and Gluconeogenesis; TCA Cycle",29,0,1.056,0.08,0.382527951710257,0.95668811832599,102,101.7,96.3,"",2.6,7,6190.9,"","",6296.3,6350.9,6049.6,6046.2,5141.3,5878.1,5816.4,6054.5,314.1,"","",5024.5,4807,4804,4378.9,3702.9,5878.1,4740.4,4831.3,"High","High","High","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q96HR3","Mediator of RNA polymerase II transcription subunit 30 OS=Homo sapiens OX=9606 GN=MED30 PE=1 SV=1",0,28.371,25,4,6,4,178,20.3,8.27,24.69,4,"metabolic process;regulation of biological process;response to stimulus","nucleus","catalytic activity;protein binding;receptor activity","Pf11315","90390","ENSG00000164758.7","MED30","8","Thyroid hormone signaling pathway","Transcriptional regulation of white adipocyte differentiation; PPARA activates gene expression; Generic Transcription Pathway","",10,0,0.914,-0.13,0.384450268697331,0.957602093519081,91.9,99.4,108.8,"",13.99,6.72,224.7,"","",251.9,237.3,248.8,182.8,245.1,276.6,283.3,255.8,11.4,"","",201,179.6,197.6,132.4,176.5,276.6,230.9,204.1,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P00491","Purine nucleoside phosphorylase OS=Homo sapiens OX=9606 GN=PNP PE=1 SV=2",0,89.097,55,12,38,12,289,32.1,6.95,85.45,12,"metabolic process;regulation of biological process;response to stimulus;transport","cytoplasm;cytoskeleton;cytosol;extracellular;nucleus;organelle lumen","catalytic activity","Pf01048","4860","ENSG00000198805.11","PNP","14","Metabolic pathways; Nicotinate and nicotinamide metabolism; Pyrimidine metabolism; Purine metabolism","Neutrophil degranulation; Purine salvage; Purine catabolism","",13,0,1.054,0.08,0.388220092156588,0.958077036016406,172.1,65.6,62.2,106.24,2.34,1.4,6391.9,"",45001.6,6564.3,6652.7,6366.2,6342.5,6173,6093.6,6071.1,6260.7,324.3,"",5.7,5238.3,5035.4,5055.4,4593.5,4446,6093.6,4948,4995.9,"High","Not Found","High","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P78559","Microtubule-associated protein 1A OS=Homo sapiens OX=9606 GN=MAP1A PE=1 SV=6",0,33.859,5,10,10,10,2803,305.3,4.92,25.74,10,"cell organization and biogenesis","cytoplasm;cytoskeleton","protein binding;structural molecule activity","Pf12072, Pf12128","4130","ENSG00000166963.12","MAP1A","15","","","",0,0,0.931,-0.1,0.385791545189726,0.958077036016406,243.1,27.4,29.5,136.56,8.37,3.16,676,"",38685.5,538.3,591.1,563.8,652.7,657.4,619.3,620.5,614.4,34.3,"",4.9,429.6,447.4,447.7,472.7,473.5,619.3,505.7,490.3,"High","Not Found","High","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","O75956","Cyclin-dependent kinase 2-associated protein 2 OS=Homo sapiens OX=9606 GN=CDK2AP2 PE=1 SV=1",0,13.305,17,4,4,1,126,13.1,9.48,12.21,4,"metabolic process;regulation of biological process","cytoplasm;nucleus","catalytic activity;protein binding","Pf09806","10263","ENSG00000167797.7","CDK2AP2","11","","","",0,2,1.082,0.11,0.389344133138177,0.958077036016406,111.4,98,90.6,"",19.56,6.36,348.9,"","",293.2,321.2,340.3,211,275.9,278.7,288.5,316.3,17.7,"","",234,243.1,270.2,152.8,198.7,278.7,235.1,252.4,"Not Found","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q13084","39S ribosomal protein L28, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL28 PE=1 SV=4",0,39.144,41,10,14,10,256,30.1,8.29,39.3,10,"cell organization and biogenesis;metabolic process","cytosol;membrane;mitochondrion;ribosome","protein binding;RNA binding;structural molecule activity","Pf00830","10573","ENSG00000086504.15","MRPL28","16","Ribosome","Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination","",7,0,1.062,0.09,0.391707409075686,0.958365038054404,101.8,102.1,96.2,"",15.82,8.7,1454.6,"","",1490.5,1427.7,1620.6,1097.1,1195.7,1411.1,1468,1338.3,73.8,"","",1189.4,1080.6,1286.9,794.6,861.2,1411.1,1196.4,1067.9,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q8WYN0","Cysteine protease ATG4A OS=Homo sapiens OX=9606 GN=ATG4A PE=1 SV=1",0,8.405,6,1,1,1,398,45.3,5.05,4.48,1,"cell organization and biogenesis;metabolic process;transport","cytoplasm;cytosol","catalytic activity;protein binding","Pf03416","115201","ENSG00000101844.17","ATG4A","X","Autophagy","Macroautophagy","Nanoparticle triggered autophagic cell death",4,0,1.1,0.14,0.395415866552397,0.960840716253914,"",157.1,142.9,"",8.11,12.53,"","","",56.4,47.7,47.9,49.7,46.5,42.3,52,39,"","","",45,36.1,38,36,33.5,42.3,42.4,31.1,"Not Found","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P82932","28S ribosomal protein S6, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS6 PE=1 SV=3",0,27.416,53,7,12,7,125,14.2,9.26,34.34,7,"cell organization and biogenesis;metabolic process","membrane;mitochondrion;ribosome","protein binding;RNA binding;structural molecule activity","Pf01250","64968","ENSG00000243927.5","MRPS6","21","Ribosome","Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination","",7,0,1.065,0.09,0.398568476743314,0.961328232502581,109.2,98.4,92.4,"",2.46,4.35,1633.9,"","",1486.3,1485.3,1458.5,1409.8,1413.6,1411.3,1287.6,1354.6,82.9,"","",1186.1,1124.2,1158.2,1021,1018.1,1411.3,1049.4,1080.9,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q9GZT3","SRA stem-loop-interacting RNA-binding protein, mitochondrial OS=Homo sapiens OX=9606 GN=SLIRP PE=1 SV=1",0,57.545,74,11,23,11,109,12.3,10.24,65.84,11,"cell organization and biogenesis;cellular component movement;metabolic process;regulation of biological process","cytoplasm;mitochondrion;nucleus","protein binding;RNA binding","Pf00076, Pf13893, Pf14259","81892","ENSG00000119705.9","SLIRP","14","","","",0,0,1.056,0.08,0.402820172030172,0.961786917145748,108.6,98.3,93.1,"",11.52,4.44,4422.9,"","",3975.5,4029.2,4392.9,3307.5,3692.4,3888.3,3949.3,3589.1,224.4,"","",3172.5,3049.7,3488.4,2395.4,2659.4,3888.3,3218.7,2864,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q68D91","Metallo-beta-lactamase domain-containing protein 2 OS=Homo sapiens OX=9606 GN=MBLAC2 PE=1 SV=3",0,21.681,23,5,5,5,279,31.4,6.92,14.97,5,"","","catalytic activity;metal ion binding","Pf00753, Pf12706","153364","ENSG00000176055.9","MBLAC2","5","","","",0,0,1.085,0.12,0.400581169041826,0.961786917145748,88.2,110.2,101.5,"",1.97,2.47,305.5,"","",382.8,375.7,393.5,380.4,351.3,338.1,358.8,351.9,15.5,"","",305.5,284.4,312.5,275.5,253,338.1,292.4,280.8,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q6P4I2","WD repeat-containing protein 73 OS=Homo sapiens OX=9606 GN=WDR73 PE=1 SV=1",0,19.971,17,5,6,5,378,41.7,5.78,16.8,5,"cell organization and biogenesis;regulation of biological process","cytoplasm;cytoskeleton;cytosol","protein binding","","84942","ENSG00000177082.12","WDR73","15","","","",0,0,0.936,-0.09,0.40296457204852,0.961786917145748,95.2,99,105.7,"",5.44,1.8,674.1,"","",691.6,723.2,637.8,710.4,765.9,746.3,733.2,750.8,34.2,"","",551.9,547.4,506.5,514.5,551.6,746.3,597.6,599.1,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q9NWU5","39S ribosomal protein L22, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL22 PE=1 SV=1",0,46.533,39,8,12,8,206,23.6,9.94,40.39,8,"cell organization and biogenesis;metabolic process","membrane;mitochondrion;ribosome","RNA binding;structural molecule activity","Pf00237","29093","ENSG00000082515.17","MRPL22","5","Ribosome","Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination","",7,0,1.067,0.09,0.405599227060259,0.962768791908567,202.8,50.2,47,125.4,7.05,3.17,1245.7,20749,"",1267.9,1247.5,1326.2,1118.8,1131.2,1183,1173.8,1222.2,63.2,5.8,"",1011.8,944.2,1053.1,810.3,814.7,1183,956.7,975.3,"High","High","High","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P28290","Protein ITPRID2 OS=Homo sapiens OX=9606 GN=ITPRID2 PE=1 SV=3",0,169.211,26,33,42,33,1259,138.3,5.19,136.31,33,"","cytoplasm;cytosol;membrane;nucleus","protein binding","Pf14722, Pf14723","6744","ENSG00000138434.16","SSFA2","2","","","",0,0,1.074,0.1,0.407866455621788,0.963248987511108,93.1,107.2,99.8,"",4.28,2.8,2010.4,"","",2313.8,2374.2,2316,2146.9,2148.2,2249.7,2105,2162.6,102,"","",1846.4,1797,1839.1,1554.9,1547.2,2249.7,1715.6,1725.7,"High","High","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P11387","DNA topoisomerase 1 OS=Homo sapiens OX=9606 GN=TOP1 PE=1 SV=2",0,157.596,37,31,69,29,765,90.7,9.31,188.48,31,"cell death;cell division;cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus","chromosome;cytoplasm;nucleus","catalytic activity;DNA binding;nucleotide binding;protein binding;RNA binding","Pf01028, Pf02919, Pf14370","7150","ENSG00000198900.5","TOP1","20","","SUMOylation of DNA replication proteins","",5,3,1.051,0.07,0.410170290730666,0.963666138412711,152.9,75.4,71.7,83.85,1.02,2.7,13318,"",52107.1,12849.1,12897.9,13117.2,13082.8,12563.9,12550.3,12160.7,11877.1,675.7,"",6.6,10253.6,9762.4,10416.3,9475.1,9048.9,12550.3,9911.1,9477.6,"High","High","High","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q14657","EKC/KEOPS complex subunit LAGE3 OS=Homo sapiens OX=9606 GN=LAGE3 PE=1 SV=2",0,13.092,29,2,3,2,143,14.8,8.63,9.02,2,"metabolic process","nucleus","protein binding","Pf09341","8270","ENSG00000196976.7","LAGE3","X","","tRNA modification in the nucleus and cytosol","",3,0,1.109,0.15,0.412668946982154,0.965905939729072,"",157.8,142.2,"",23.57,13.77,"","","",28.3,21.1,23.4,15.7,18.3,18.3,22,24.1,"","","",22.6,16,18.6,11.4,13.2,18.3,17.9,19.2,"Not Found","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q52LR7","Enhancer of polycomb homolog 2 OS=Homo sapiens OX=9606 GN=EPC2 PE=1 SV=2",0,23.453,11,7,7,7,807,91,8.73,21.73,7,"cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus","nucleus","catalytic activity","Pf06752, Pf10513","26122","ENSG00000135999.11","EPC2","2","","","",0,0,0.917,-0.12,0.416608489671532,0.966392175256782,69,110.5,120.5,"",7.88,5.91,106.4,"","",148.7,173.7,167.5,178.9,194.9,185.3,169,186.7,5.4,"","",118.7,131.5,133,129.6,140.4,185.3,137.7,149,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q15833","Syntaxin-binding protein 2 OS=Homo sapiens OX=9606 GN=STXBP2 PE=1 SV=2",0,104.127,35,19,24,19,593,66.4,6.55,80.66,19,"regulation of biological process;transport","cytosol;extracellular;membrane;vacuole","protein binding","Pf00995","6813","ENSG00000076944.15","STXBP2","19","","Platelet degranulation ; Other interleukin signaling","Insulin Signaling",9,0,1.071,0.1,0.417895317792591,0.96703672169786,96.8,105.1,98.1,"",2.65,2.19,2367.2,"","",2569.9,2520.7,2568.6,2682.4,2438.5,2358.8,2443.2,2342.6,120.1,"","",2050.8,1907.9,2039.7,1942.7,1756.3,2358.8,1991.2,1869.3,"High","High","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","C9JI98","Transmembrane protein 238 OS=Homo sapiens OX=9606 GN=TMEM238 PE=1 SV=1",0,15.501,19,2,2,2,176,18,11.53,7.92,2,"","membrane","","Pf15125","388564","ENSG00000233493.3","TMEM238","19","","","",0,0,1.073,0.1,0.420097911713583,0.968780675970029,76.7,115.6,107.7,"",4.01,9.91,82.8,"","",125.1,124.3,133,121.1,130.1,123.1,105.2,109.7,4.2,"","",99.8,94.1,105.6,87.7,93.7,123.1,85.7,87.5,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P78347","General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2",0,250.195,50,51,94,51,998,112.3,6.39,283.72,51,"cellular homeostasis;metabolic process;regulation of biological process;response to stimulus","cytoplasm;membrane;nucleus","DNA binding;protein binding","Pf02946","2969","ENSG00000263001.5","GTF2I","7","Basal transcription factors; Herpes simplex infection; cGMP-PKG signaling pathway","","B Cell Receptor Signaling Pathway",4,0,0.952,-0.07,0.422578563898372,0.969589882763903,101.5,96.8,101.7,"",2.92,1.57,14070.9,"","",13584.1,13266.9,13934.8,13030.1,13761.9,14034,14268.4,14173.5,713.9,"","",10840.2,10041.7,11065.6,9436.9,9911.7,14034,11628.9,11310.1,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q9BYD6","39S ribosomal protein L1, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL1 PE=1 SV=2",0,57.147,35,9,17,9,325,36.9,8.78,56.19,9,"cell organization and biogenesis;metabolic process","membrane;mitochondrion;ribosome","protein binding;RNA binding;structural molecule activity","Pf00687, Pf13003","65008","ENSG00000169288.17","MRPL1","4","Ribosome","Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination","",7,0,1.057,0.08,0.425820382439177,0.971783802994479,154,75,71,76.75,1.86,1.97,3817.8,12878.7,"",3450.4,3384.9,3509.5,3371.3,3270.2,3173,3195,3309.6,193.7,3.6,"",2753.4,2562,2786.9,2441.6,2355.3,3173,2604,2641,"High","High","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q92785","Zinc finger protein ubi-d4 OS=Homo sapiens OX=9606 GN=DPF2 PE=1 SV=2",0,73.677,35,12,14,12,391,44.1,6.33,50.75,12,"cell death;metabolic process;regulation of biological process;response to stimulus","cytoplasm;cytosol;nucleus","DNA binding;metal ion binding;protein binding","Pf00628, Pf14051","5977","ENSG00000133884.9","DPF2","11","","","",0,0,0.95,-0.07,0.428227357077026,0.972881548562412,96,99.4,104.6,"",1.7,1.39,1482.2,"","",1537,1533,1565.8,1502,1598.2,1623.4,1649.7,1607.4,75.2,"","",1226.5,1160.3,1243.4,1087.8,1151.1,1623.4,1344.5,1282.7,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q9NR48","Histone-lysine N-methyltransferase ASH1L OS=Homo sapiens OX=9606 GN=ASH1L PE=1 SV=2",0,102.648,8,19,21,19,2969,332.6,9.39,73.32,19,"cell communication;cell organization and biogenesis;metabolic process;regulation of biological process","chromosome;Golgi;nucleus","catalytic activity;DNA binding;metal ion binding;protein binding","Pf00439, Pf00628, Pf00856, Pf01426","55870","ENSG00000116539.12","ASH1L","1","Tight junction; Lysine degradation","PKMTs methylate histone lysines","Histone Modifications",6,0,0.941,-0.09,0.433036552175878,0.973579433869585,78.3,107.5,114.2,"",1.12,1.53,510.5,"","",703.6,698.5,688.3,706,745.2,728.2,744.3,755.8,25.9,"","",561.5,528.7,546.6,511.3,536.7,728.2,606.6,603.1,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","O00330","Pyruvate dehydrogenase protein X component, mitochondrial OS=Homo sapiens OX=9606 GN=PDHX PE=1 SV=3",0,45.146,24,11,12,11,501,54.1,8.66,35.48,11,"metabolic process;regulation of biological process","mitochondrion;organelle lumen","catalytic activity;protein binding","Pf00198, Pf00364, Pf02817","8050","ENSG00000110435.11","PDHX","11","Metabolic pathways","Regulation of pyruvate dehydrogenase (PDH) complex; Signaling by Retinoic Acid; Glyoxylate metabolism and glycine degradation","Amino Acid metabolism; Glycolysis and Gluconeogenesis",13,0,1.059,0.08,0.434987179054069,0.973579433869585,104.9,100.3,94.8,"",5.93,2.58,1509.8,"","",1364.7,1382.7,1508.1,1533.3,1339.9,1342.7,1413.4,1385.1,76.6,"","",1089,1046.6,1197.6,1110.5,965,1342.7,1151.9,1105.3,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P40306","Proteasome subunit beta type-10 OS=Homo sapiens OX=9606 GN=PSMB10 PE=1 SV=1",0,12.536,12,3,4,3,273,28.9,7.81,13.12,3,"metabolic process;regulation of biological process;response to stimulus;transport","cytoplasm;cytosol;nucleus;proteasome","catalytic activity;protein binding","Pf00227, Pf12465","5699","ENSG00000205220.11","PSMB10","16","Proteasome","Regulation of RAS by GAPs; CDT1 association with the CDC6:ORC:origin complex; Downstream TCR signaling; UCH proteinases; NIK-->noncanonical NF-kB signaling; Hh mutants that don't undergo autocatalytic processing are degraded by ERAD; SCF-beta-TrCP mediated degradation of Emi1; Cross-presentation of soluble exogenous antigens (endosomes); Separation of Sister Chromatids; Vpu mediated degradation of CD4; Hedgehog ligand biogenesis; Regulation of RUNX2 expression and activity; Ub-specific processing proteases; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; ER-Phagosome pathway; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; ABC-family proteins mediated transport; Regulation of activated PAK-2p34 by proteasome mediated degradation; CDK-mediated phosphorylation and removal of Cdc6; FCERI mediated NF-kB activation; Neddylation; Autodegradation of the E3 ubiquitin ligase COP1; G2/M Checkpoints; Regulation of RUNX3 expression and activity; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Regulation of expression of SLITs and ROBOs; Removal of licensing factors from origins; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; Regulation of PTEN stability and activity; Regulation of DNA replication; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; Vif-mediated degradation of APOBEC3G; Antigen processing: Ubiquitination & Proteasome degradation; GLI3 is processed to GLI3R by the proteasome; SCF(Skp2)-mediated degradation of p27/p21; APC/C:Cdc20 mediated degradation of Securin; Interleukin-1 family signaling; AUF1 (hnRNP D0) binds and destabilizes mRNA; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; The role of GTSE1 in G2/M progression after G2 checkpoint; Regulation of ornithine decarboxylase (ODC); Interleukin-20 family signaling; Hedgehog 'on' state; Ubiquitin-dependent degradation of Cyclin D1; Degradation of DVL; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Degradation of AXIN; Autodegradation of Cdh1 by Cdh1:APC/C; Asymmetric localization of PCP proteins; Orc1 removal from chromatin; M/G1 Transition; Activation of NF-kappaB in B cells; Degradation of beta-catenin by the destruction complex; MAPK6/MAPK4 signaling; Dectin-1 mediated noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosis","Proteasome Degradation",150,0,1.061,0.09,0.434214345600734,0.973579433869585,107.4,99.1,93.4,"",6.14,4.08,965.8,"","",887.5,894.4,843.3,975.9,823.9,856,799.1,876.5,49,"","",708.2,677,669.7,706.8,593.4,856,651.3,699.4,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P05362","Intercellular adhesion molecule 1 OS=Homo sapiens OX=9606 GN=ICAM1 PE=1 SV=2",0,54.388,23,9,14,9,532,57.8,7.99,43.36,9,"cell communication;cell organization and biogenesis;cellular component movement;cellular homeostasis;defense response;regulation of biological process;response to stimulus","cell surface;membrane","protein binding;receptor activity;signal transducer activity","Pf03921, Pf07679, Pf13895","3383","ENSG00000090339.8","ICAM1","19","Influenza A; HTLV-I infection; Cell adhesion molecules (CAMs); Rheumatoid arthritis; Viral myocarditis; NF-kappa B signaling pathway; TNF signaling pathway; Malaria; AGE-RAGE signaling pathway in diabetic complications; African trypanosomiasis; Natural killer cell mediated cytotoxicity; Staphylococcus aureus infection; Epstein-Barr virus infection; Leukocyte transendothelial migration","Integrin cell surface interactions; Interleukin-10 signaling; Interleukin-4 and 13 signaling; Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell; Interferon gamma signaling","Selenium Micronutrient Network; Vitamin B12 Metabolism; Folate Metabolism; RANKL/RANK (Receptor activator of NFKB (ligand)) Signaling Pathway; Interleukin-11 Signaling Pathway; Spinal Cord Injury; IL1 and megakaryocytes in obesity; Photodynamic therapy-induced NF-kB survival signaling; VEGFA-VEGFR2 Signaling Pathway; Type II interferon signaling (IFNG)",35,0,0.94,-0.09,0.437644906398649,0.975252122706192,98.4,97.7,103.9,"",5.46,11.5,741.1,"","",720.3,751.4,758.7,671.6,773.5,969.5,777.4,788.1,37.6,"","",574.8,568.7,602.5,486.4,557.1,969.5,633.6,628.9,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","O76003","Glutaredoxin-3 OS=Homo sapiens OX=9606 GN=GLRX3 PE=1 SV=2",0,94.195,41,14,28,14,335,37.4,5.39,82.28,14,"cell organization and biogenesis;cellular homeostasis;metabolic process;regulation of biological process","cytoplasm;cytosol;nucleus;spliceosomal complex","catalytic activity;metal ion binding;protein binding;RNA binding","Pf00085, Pf00462, Pf02114, Pf02966, Pf04908, Pf13098, Pf13905","10539","ENSG00000108010.11","GLRX3","10","","Iron uptake and transport","",2,0,1.048,0.07,0.442419137214766,0.976296031465253,104.1,100.3,95.7,"",4.77,3.63,6772.3,"","",6867.4,6753.1,6305.5,6249.2,6419.9,6288.2,6166.5,5892.9,343.6,"","",5480.2,5111.4,5007.2,4525.9,4623.8,6288.2,5025.8,4702.4,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q0VDG4","Secernin-3 OS=Homo sapiens OX=9606 GN=SCRN3 PE=1 SV=1",0,16.634,12,4,4,4,424,48.5,5.55,11.91,4,"metabolic process;transport","","catalytic activity","Pf03577","79634","ENSG00000144306.14","SCRN3","2","","","",0,0,1.079,0.11,0.441935451481741,0.976296031465253,239.9,31.2,28.9,135.31,3.03,5.08,435.6,"",19737.5,383.7,378.6,373.3,400.1,379.9,343,342.1,363.9,22.1,"",2.5,306.2,286.6,296.4,289.8,273.6,343,278.8,290.4,"High","Not Found","High","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","O14524","Nuclear envelope integral membrane protein 1 OS=Homo sapiens OX=9606 GN=NEMP1 PE=1 SV=2",0,11.496,5,2,3,2,444,50.6,6.93,10.18,2,"","membrane;nucleus","","Pf10225","23306","ENSG00000166881.9","TMEM194A; NEMP1","12","","","",0,0,0.934,-0.1,0.44358818088952,0.976347403024502,101.9,95.6,102.4,"",8.78,6.04,425.7,"","",396,402.8,391.9,469.2,438.5,417.3,390.3,448,21.6,"","",316,304.9,311.2,339.8,315.8,417.3,318.1,357.5,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q14642","Inositol polyphosphate-5-phosphatase A OS=Homo sapiens OX=9606 GN=INPP5A PE=1 SV=1",0,5.476,7,3,4,3,412,47.8,7.03,11.09,3,"metabolic process;regulation of biological process;response to stimulus","membrane","catalytic activity;protein binding","","3632","ENSG00000068383.18","INPP5A","10","Phosphatidylinositol signaling system; Metabolic pathways; Inositol phosphate metabolism","Synthesis of IP2, IP, and Ins in the cytosol","",6,0,0.9,-0.15,0.445748609412744,0.977220702307031,"",142.1,157.9,"",12.71,13.72,"","","",25.4,21.3,24.1,19.1,21.5,23.5,26.9,29.3,"","","",20.3,16.1,19.1,13.8,15.5,23.5,21.9,23.4,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q14684","Ribosomal RNA processing protein 1 homolog B OS=Homo sapiens OX=9606 GN=RRP1B PE=1 SV=3",0,122.645,32,21,28,21,758,84.4,9.76,89.68,21,"metabolic process;regulation of biological process;response to stimulus","cytosol;nucleus","protein binding;RNA binding","Pf05997","23076","ENSG00000160208.12","RRP1B","21","","","",0,0,1.067,0.09,0.450780549875909,0.97871460618968,149.4,77.7,72.8,89.37,5.58,2.43,2339.6,10374.5,"",2551.6,2573.3,2587.8,2293.3,2390.2,2489.6,2411.1,2350.4,118.7,2.9,"",2036.2,1947.7,2055,1660.9,1721.5,2489.6,1965.1,1875.6,"High","High","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P52747","Zinc finger protein 143 OS=Homo sapiens OX=9606 GN=ZNF143 PE=1 SV=2",0,23.603,9,6,7,6,638,68.9,6.05,16.95,6,"metabolic process;regulation of biological process","nucleus","DNA binding;metal ion binding;protein binding","Pf00096, Pf13465","7702","ENSG00000166478.9","ZNF143","11","","RNA Polymerase III Abortive And Retractive Initiation; RNA polymerase II transcribes snRNA genes; RNA Polymerase III Transcription Initiation From Type 3 Promoter","",7,0,0.94,-0.09,0.451611883328688,0.97871460618968,97.7,98,104.3,"",4.28,1.71,605.1,"","",615.3,561.4,599.2,616.1,644,638.5,648.2,664.3,30.7,"","",491,424.9,475.8,446.2,463.8,638.5,528.3,530.1,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P46939","Utrophin OS=Homo sapiens OX=9606 GN=UTRN PE=1 SV=2",0,231.505,19,60,68,58,3433,394.2,5.33,202.8,60,"cell organization and biogenesis;regulation of biological process;response to stimulus","cytoplasm;cytoskeleton;membrane","metal ion binding;protein binding","Pf00307, Pf00397, Pf00435, Pf00569, Pf09068, Pf09069, Pf11971","7402","ENSG00000152818.18","UTRN","6","","","Primary Focal Segmental Glomerulosclerosis FSGS",1,2,0.956,-0.06,0.466275258560787,0.978735523350172,112.3,91.7,95.9,29.12,4.1,6.49,5889.3,8943.5,"",5775.8,5922.2,5928.1,6346.6,6062.8,6263.1,6131.4,6961,298.8,2.5,"",4609.1,4482.5,4707.5,4596.5,4366.6,6263.1,4997.2,5554.7,"High","High","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P07951-2","Isoform 2 of Tropomyosin beta chain OS=Homo sapiens OX=9606 GN=TPM2",0,128.741,55,24,77,4,284,33,4.67,218.32,24,"cell organization and biogenesis;cellular component movement;regulation of biological process","cytoskeleton;cytosol","protein binding;structural molecule activity","Pf00261, Pf12718","7169","ENSG00000198467.13","TPM2","9","","","Striated Muscle Contraction",1,7,1.066,0.09,0.459940971733345,0.978735523350172,102.6,101.8,95.5,"",1.19,2.5,2136.5,"","",2142.8,2131.1,2108.7,2085.8,1976,1913,2028.4,2002.2,108.4,"","",1710,1613,1674.5,1510.6,1423.2,1913,1653.2,1597.7,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q09472","Histone acetyltransferase p300 OS=Homo sapiens OX=9606 GN=EP300 PE=1 SV=2",0,95.172,9,20,24,9,2414,264,8.5,75.4,20,"cell death;cell differentiation;cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus","chromosome;cytoplasm;cytosol;nucleus","catalytic activity;DNA binding;metal ion binding;protein binding;RNA binding","Pf00439, Pf00569, Pf02135, Pf02172, Pf06001, Pf08214, Pf09030, Pf09770","2033","ENSG00000100393.12","EP300","22","Epstein-Barr virus infection; Cell cycle; Hepatitis B; Jak-STAT signaling pathway; Tuberculosis; Prostate cancer; FoxO signaling pathway; Notch signaling pathway; Viral carcinogenesis; Melanogenesis; Thyroid hormone signaling pathway; Huntington's disease; cAMP signaling pathway; Glucagon signaling pathway; MicroRNAs in cancer; Herpes simplex infection; Renal cell carcinoma; HIF-1 signaling pathway; Adherens junction; Long-term potentiation; TGF-beta signaling pathway; Wnt signaling pathway; Pathways in cancer; Influenza A; HTLV-I infection","NOTCH1 Intracellular Domain Regulates Transcription; Transcriptional regulation of white adipocyte differentiation; TRAF6 mediated IRF7 activation; TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest; Activation of anterior HOX genes in hindbrain development during early embryogenesis; Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants; PPARA activates gene expression; Factors involved in megakaryocyte development and platelet production; RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known; Formation of the beta-catenin:TCF transactivating complex; Pre-NOTCH Transcription and Translation; BMAL1:CLOCK,NPAS2 activates circadian gene expression; Metalloprotease DUBs; LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production; PI5P Regulates TP53 Acetylation; RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function; Gap-filling DNA repair synthesis and ligation in TC-NER; Polo-like kinase mediated events; RUNX3 regulates p14-ARF; RORA activates gene expression; Regulation of gene expression by Hypoxia-inducible Factor; HATs acetylate histones; Regulation of TP53 Activity through Methylation; Formation of TC-NER Pre-Incision Complex; TRAF3-dependent IRF activation pathway; CD209 (DC-SIGN) signaling; NOTCH2 intracellular domain regulates transcription; Activation of the TFAP2 (AP-2) family of transcription factors; Attenuation phase; Constitutive Signaling by NOTCH1 PEST Domain Mutants; Regulation of RUNX3 expression and activity; RUNX3 regulates NOTCH signaling; Dual incision in TC-NER; B-WICH complex positively regulates rRNA expression","Androgen receptor signaling pathway; Energy Metabolism; Cell Cycle; Integrated Breast Cancer Pathway; Signaling Pathways in Glioblastoma; Aryl Hydrocarbon Receptor; Aryl Hydrocarbon Receptor Pathway; Kit receptor signaling pathway; Initiation of transcription and translation elongation at the HIV-1 LTR; Pathways Affected in Adenoid Cystic Carcinoma; Hematopoietic Stem Cell Gene Regulation by GABP alpha/beta Complex; TGF-beta Signaling Pathway; IL-4 Signaling Pathway; Wnt Signaling Pathway and Pluripotency; TGF-beta Receptor Signaling; Notch Signaling Pathway; Sudden Infant Death Syndrome (SIDS) Susceptibility Pathways",130,1,0.94,-0.09,0.458570148926424,0.978735523350172,98.5,97.7,103.9,"",4.36,3.06,904.7,"","",898.6,924.7,896,833.4,953.2,1006,956.2,938.2,45.9,"","",717.1,699.9,711.5,603.6,686.5,1006,779.3,748.7,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q9BTA9","WW domain-containing adapter protein with coiled-coil OS=Homo sapiens OX=9606 GN=WAC PE=1 SV=3",0,74.576,22,15,22,15,647,70.7,9.45,64.04,15,"cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus","nucleus;spliceosomal complex","protein binding","Pf00397","51322","ENSG00000095787.21","WAC","10","","E3 ubiquitin ligases ubiquitinate target proteins","",4,0,0.957,-0.06,0.475889541254592,0.978735523350172,96.6,99.5,103.9,"",8.79,4.85,1909.9,"","",1931.7,1951,1984.1,2312.6,2016.6,1963.4,2095.8,2193.9,96.9,"","",1541.5,1476.7,1575.6,1674.9,1452.4,1963.4,1708.1,1750.7,"High","High","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q12899","Tripartite motif-containing protein 26 OS=Homo sapiens OX=9606 GN=TRIM26 PE=1 SV=1",0,56.727,26,12,16,12,539,62.1,5.03,52.22,12,"defense response;regulation of biological process;response to stimulus","cytoplasm;cytosol;nucleus","catalytic activity;DNA binding;metal ion binding;protein binding","Pf00097, Pf00622, Pf00643, Pf05290, Pf13445, Pf13639, Pf13765, Pf13920, Pf13923, Pf14634, Pf14835, Pf15227","7726","ENSG00000230230.7; ENSG00000231002.7; ENSG00000228881.7; ENSG00000137313.15; ENSG00000231641.9; ENSG00000234127.8; ENSG00000226060.7; ENSG00000234046.7","TRIM26","6; CHR_HSCHR6_MHC_COX_CTG1; CHR_HSCHR6_MHC_MANN_CTG1; CHR_HSCHR6_MHC_APD_CTG1; CHR_HSCHR6_MHC_QBL_CTG1; CHR_HSCHR6_MHC_MCF_CTG1; CHR_HSCHR6_MHC_DBB_CTG1; CHR_HSCHR6_MHC_SSTO_CTG1","","Interferon gamma signaling","",4,0,0.944,-0.08,0.460190424377549,0.978735523350172,194.6,51.2,54.2,121.08,3.61,4.46,859.3,11090,"",816,808.6,758.6,821.5,828.8,836.1,908.3,886.1,43.6,3.1,"",651.2,612,602.4,595,596.9,836.1,740.3,707.1,"High","High","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P16083","Ribosyldihydronicotinamide dehydrogenase [quinone] OS=Homo sapiens OX=9606 GN=NQO2 PE=1 SV=5",0,46.406,33,8,16,8,231,25.9,6.29,49.72,8,"metabolic process;regulation of biological process;response to stimulus","cytoplasm;cytosol","catalytic activity;metal ion binding;nucleotide binding;protein binding","Pf02525, Pf03358","4835","ENSG00000124588.19","NQO2","6","","Phase I - Functionalization of compounds","Photodynamic therapy-induced NFE2L2 (NRF2) survival signaling",4,0,1.054,0.08,0.477494187597814,0.978735523350172,192,55.4,52.6,112.86,5.68,6.76,1768,15740.6,"",1501.6,1479.5,1543.1,1676.1,1449.1,1300.8,1534.6,1439.6,89.7,4.4,"",1198.3,1119.8,1225.4,1213.9,1043.7,1300.8,1250.7,1148.8,"High","High","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q9UI26","Importin-11 OS=Homo sapiens OX=9606 GN=IPO11 PE=1 SV=1",0,40.557,8,7,9,7,975,112.5,5.25,30.85,7,"transport","cytoplasm;cytosol;nucleus","protein binding;transporter activity","Pf03810","51194","ENSG00000086200.16","IPO11","5","","","",0,0,0.952,-0.07,0.460279381820364,0.978735523350172,96,99.5,104.5,"",4.25,1.67,1344.2,"","",1448.6,1411.3,1310.7,1373.3,1507,1463.6,1461.1,1452.2,68.2,"","",1156,1068.2,1040.8,994.6,1085.4,1463.6,1190.8,1158.8,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q12846","Syntaxin-4 OS=Homo sapiens OX=9606 GN=STX4 PE=1 SV=2",0,32.562,32,10,15,10,297,34.2,6.28,39.64,10,"cell organization and biogenesis;regulation of biological process;response to stimulus;transport","cell surface;cytoplasm;cytosol;endosome;membrane;vacuole","enzyme regulator activity;protein binding","Pf00804, Pf05739","6810","ENSG00000103496.14","STX4","16","Vasopressin-regulated water reabsorption; SNARE interactions in vesicular transport","Translocation of GLUT4 to the plasma membrane; Clathrin derived vesicle budding; Disinhibition of SNARE formation; ER-Phagosome pathway; Other interleukin signaling","Insulin Signaling",20,0,1.056,0.08,0.472100485217871,0.978735523350172,94.8,105.4,99.8,"",6.07,4.63,678,"","",722.2,730.1,777,822,752.5,711.2,715.7,671.8,34.4,"","",576.3,552.6,617,595.3,542,711.2,583.3,536.1,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","O95429","BAG family molecular chaperone regulator 4 OS=Homo sapiens OX=9606 GN=BAG4 PE=1 SV=1",0,26.353,16,5,7,5,457,49.6,5.12,25.6,5,"cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus","cytoplasm;cytosol;membrane;nucleus","enzyme regulator activity;nucleotide binding;protein binding;RNA binding;signal transducer activity","Pf02179","9530","ENSG00000156735.10","BAG4","8","TNF signaling pathway","Regulation of HSF1-mediated heat shock response; TNF signaling; Signaling by plasma membrane FGFR1 fusions","Oxidative Damage",15,0,0.944,-0.08,0.455857341615639,0.978735523350172,92,101,107,"",1.9,2.53,652.4,"","",717.9,741.4,711,715,763.8,791.8,748,754.4,33.1,"","",572.9,561.2,564.6,517.8,550.1,791.8,609.6,602,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q9Y296","Trafficking protein particle complex subunit 4 OS=Homo sapiens OX=9606 GN=TRAPPC4 PE=1 SV=1",0,19.942,26,5,5,5,219,24.3,6.21,15.21,5,"cell organization and biogenesis;transport","cytosol;endoplasmic reticulum;Golgi;membrane","protein binding","Pf04099, Pf04628","51399","ENSG00000280495.4; ENSG00000196655.11","TRAPPC4","11; CHR_HG2217_PATCH","","COPII (Coat Protein 2) Mediated Vesicle Transport; RAB GEFs exchange GTP for GDP on RABs; Syndecan interactions","",13,0,1.056,0.08,0.457017012343063,0.978735523350172,106.9,99.2,94,"",7.94,4.33,685.9,"","",614.7,659.3,675.5,564.3,634.4,599.2,606.9,570.9,34.8,"","",490.5,499,536.4,408.7,456.9,599.2,494.6,455.6,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q96A57","Transmembrane protein 230 OS=Homo sapiens OX=9606 GN=TMEM230 PE=1 SV=1",0,15.69,28,4,5,4,120,13.2,9.31,10.46,4,"transport","endoplasmic reticulum;endosome;Golgi;membrane;vacuole","","Pf05915","29058","ENSG00000089063.14","TMEM230","20","","","",0,0,0.942,-0.09,0.472783747922958,0.978735523350172,96.8,98.6,104.6,"",2.13,2.58,890.9,"","",923.1,918.2,882.1,895.6,991.6,934,953,972.2,45.2,"","",736.6,695,700.5,648.6,714.2,934,776.7,775.8,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P40337","von Hippel-Lindau disease tumor suppressor OS=Homo sapiens OX=9606 GN=VHL PE=1 SV=2",0,11.412,14,3,3,3,213,24.1,4.73,10.46,3,"cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus","cytoplasm;cytosol;endoplasmic reticulum;membrane;mitochondrion;nucleus","catalytic activity;protein binding","Pf01847","7428","ENSG00000134086.7","VHL","3","Ubiquitin mediated proteolysis; Renal cell carcinoma; HIF-1 signaling pathway; Pathways in cancer","Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; Antigen processing: Ubiquitination & Proteasome degradation; Neddylation","Amplification and Expansion of Oncogenic Pathways as Metastatic Traits",17,0,1.063,0.09,0.477754619117752,0.978735523350172,100.1,103,96.9,"",6.84,2.6,76.9,"","",89.8,78.6,79.7,78,71.4,75.1,75.7,73.8,3.9,"","",71.7,59.5,63.3,56.5,51.4,75.1,61.7,58.9,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q96NL8","Protein C8orf37 OS=Homo sapiens OX=9606 GN=C8orf37 PE=1 SV=1",0,8.563,13,3,3,3,207,23.4,6.95,8.39,3,"","cytoplasm;cytosol;membrane","protein binding","Pf14996","157657","ENSG00000156172.5","C8orf37","8","","","",0,0,0.919,-0.12,0.477892778027555,0.978735523350172,"",143.7,156.3,"",4.38,5.04,"","","",56.5,56.9,57.5,52.2,64.8,58,60.1,63.4,"","","",45.1,43.1,45.7,37.8,46.7,58,49,50.6,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P63316","Troponin C, slow skeletal and cardiac muscles OS=Homo sapiens OX=9606 GN=TNNC1 PE=1 SV=1",1E-3,4.976,7,1,1,1,161,18.4,4.18,3.53,1,"cellular component movement;regulation of biological process;response to stimulus","cytosol","metal ion binding;protein binding","Pf00036, Pf13202, Pf13405, Pf13499, Pf13833","7134","ENSG00000114854.7","TNNC1","3","Calcium signaling pathway; Dilated cardiomyopathy; Cardiac muscle contraction; Hypertrophic cardiomyopathy (HCM); Adrenergic signaling in cardiomyocytes","Striated Muscle Contraction","MFAP5-mediated ovarian cancer cell motility and invasiveness; Striated Muscle Contraction",9,0,0.922,-0.12,0.474928090422661,0.978735523350172,102.6,94.7,102.7,"",12.75,10.03,167.5,"","",153.6,177.2,129.2,155.6,180.4,155.9,187.5,154,8.5,"","",122.6,134.1,102.6,112.7,129.9,155.9,152.8,122.9,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q96DE5","Anaphase-promoting complex subunit 16 OS=Homo sapiens OX=9606 GN=ANAPC16 PE=1 SV=1",0,13.005,31,3,5,3,110,11.7,4.97,7.49,3,"cell division;metabolic process;regulation of biological process","chromosome;cytoplasm;cytosol;nucleus","","","119504","ENSG00000166295.8","ANAPC16","10","","Inactivation of APC/C via direct inhibition of the APC/C complex; APC/C:Cdc20 mediated degradation of Cyclin B; Separation of Sister Chromatids; Autodegradation of Cdh1 by Cdh1:APC/C; Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; APC-Cdc20 mediated degradation of Nek2A; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Senescence-Associated Secretory Phenotype (SASP); Phosphorylation of the APC/C; APC/C:Cdc20 mediated degradation of Securin","",28,0,0.938,-0.09,0.482528164762308,0.979367287344774,105.7,94.1,100.3,"",6.04,5.19,445.4,"","",414.9,399.3,393.8,358.9,441.5,424.1,421.1,389.4,22.6,"","",331.1,302.2,312.7,259.9,318,424.1,343.2,310.7,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P26038","Moesin OS=Homo sapiens OX=9606 GN=MSN PE=1 SV=3",0,443.502,60,51,253,36,577,67.8,6.4,626.35,51,"cell differentiation;cell organization and biogenesis;cell proliferation;cellular component movement;regulation of biological process;response to stimulus","cell surface;cytoplasm;cytoskeleton;cytosol;membrane;nucleus","protein binding;RNA binding;structural molecule activity","Pf00373, Pf00769, Pf09379, Pf09380","4478","ENSG00000147065.16","MSN","X","Measles; Proteoglycans in cancer; Regulation of actin cytoskeleton; Leukocyte transendothelial migration","Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation; Interleukin-12 family signaling; Recycling pathway of L1","Glial Cell Differentiation; AGE/RAGE pathway; Regulation of Actin Cytoskeleton",16,23,1.043,0.06,0.485874480350107,0.981959010756837,108,98,93.9,17.75,1.27,2.79,38562.3,40067,28422,34735.5,35241.4,35627.2,34686.9,32254,33640.8,34523.8,33426.7,1956.5,11.2,3.6,27719.1,26674.2,28291.4,25121.7,23230.2,33640.8,28137.3,26673.7,"High","High","High","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q68CZ2","Tensin-3 OS=Homo sapiens OX=9606 GN=TNS3 PE=1 SV=2",0,116.441,20,22,27,21,1445,155.2,6.81,90.43,22,"cellular component movement;regulation of biological process","cytosol","protein binding","Pf00017, Pf08416, Pf10409","64759","ENSG00000136205.16","TNS3","7","","MET interacts with TNS proteins","",5,1,0.957,-0.06,0.489092382353345,0.981959010756837,168,64.6,67.4,107.54,6.81,1.37,3212.7,23610.9,"",3201.4,3502.7,3096.7,3564.1,3480.7,3498.4,3496.4,3586.7,163,6.6,"",2554.7,2651.2,2459.1,2581.3,2506.9,3498.4,2849.6,2862.1,"High","High","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P30405","Peptidyl-prolyl cis-trans isomerase F, mitochondrial OS=Homo sapiens OX=9606 GN=PPIF PE=1 SV=1",0,78.826,68,15,27,13,207,22,9.38,80.95,15,"cell death;cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus","membrane;mitochondrion;organelle lumen","catalytic activity;protein binding","Pf00160","10105","ENSG00000108179.13","PPIF","10","cGMP-PKG signaling pathway; Toxoplasmosis; Parkinson's disease; Calcium signaling pathway; Huntington's disease","","",5,1,1.042,0.06,0.50343659674619,0.981959010756837,164.8,69,66.2,92.01,13,2.54,5514.8,"",26053.5,4952.6,4966.2,5073.1,6382.4,4792.1,4687.1,4982.6,4838,279.8,"",3.3,3952.2,3758.9,4028.5,4622.4,3451.4,4687.1,4060.9,3860.6,"High","Not Found","High","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q6XZF7","Dynamin-binding protein OS=Homo sapiens OX=9606 GN=DNMBP PE=1 SV=1",0,53.97,9,13,16,13,1577,177.2,5.39,46.11,13,"regulation of biological process;response to stimulus","cytoplasm;cytoskeleton;Golgi","protein binding","Pf00018, Pf00621, Pf03114, Pf07653, Pf14604","23268","ENSG00000107554.16","DNMBP","10","","","",0,0,0.932,-0.1,0.499945458763056,0.981959010756837,72.3,109.9,117.8,"",3.26,3.91,151.8,"","",227.1,244.3,231.1,230.3,264.2,246,248.8,241.7,7.7,"","",181.2,184.9,183.5,166.8,190.3,246,202.8,192.9,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q8WWH5","Probable tRNA pseudouridine synthase 1 OS=Homo sapiens OX=9606 GN=TRUB1 PE=1 SV=1",0,40.728,29,8,10,8,349,37.2,8.25,31.26,8,"metabolic process","mitochondrion","catalytic activity;RNA binding","Pf01509","142940","ENSG00000165832.5","TRUB1","10","","","",0,0,1.054,0.08,0.500720231116661,0.981959010756837,99.5,102.9,97.6,"",2.47,3.15,1285.1,"","",1333,1324.2,1289.1,1369,1266,1309.3,1255.7,1212.7,65.2,"","",1063.7,1002.3,1023.7,991.5,911.8,1309.3,1023.4,967.7,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q96G23","Ceramide synthase 2 OS=Homo sapiens OX=9606 GN=CERS2 PE=1 SV=1",0,26.099,16,6,8,6,380,44.8,8.98,19.08,6,"metabolic process;regulation of biological process","endoplasmic reticulum;membrane;nucleus","catalytic activity;DNA binding;protein binding","Pf03798","29956","ENSG00000143418.19","CERS2","1","Sphingolipid metabolism; Sphingolipid signaling pathway; Metabolic pathways","Sphingolipid de novo biosynthesis","Sphingolipid Metabolism",8,0,1.052,0.07,0.493892742087538,0.981959010756837,102.3,101.4,96.3,"",5.54,6.53,717.4,"","",726.7,714.5,708.2,640.7,648.5,696.8,745.9,655.7,36.4,"","",579.9,540.8,562.4,464,467.1,696.8,607.9,523.2,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q7Z6K3","Protein prenyltransferase alpha subunit repeat-containing protein 1 OS=Homo sapiens OX=9606 GN=PTAR1 PE=1 SV=2",0,18.931,14,6,6,6,402,46.4,6.99,13.6,6,"metabolic process","cytoplasm","catalytic activity","Pf01239","375743","ENSG00000188647.12","PTAR1","9","","","",0,0,0.937,-0.09,0.48775443588994,0.981959010756837,101.3,96.2,102.6,"",0.8,5.51,344.9,"","",324.2,329.9,326.2,328.9,362.4,346.5,352.3,318.1,17.5,"","",258.7,249.7,259,238.2,261,346.5,287.1,253.8,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","O95789","Zinc finger MYM-type protein 6 OS=Homo sapiens OX=9606 GN=ZMYM6 PE=1 SV=2",0,11.933,3,3,3,3,1325,148,8.22,6.04,3,"cell organization and biogenesis;development;regulation of biological process","cytoplasm;nucleus","DNA binding;metal ion binding","Pf06467","9204","ENSG00000163867.16","ZMYM6","1","","","",0,0,0.913,-0.13,0.487164854002884,0.981959010756837,"",143.2,156.8,"",9.28,8.69,"","","",30.2,36.7,37.1,36,43.9,40.3,39.4,35.5,"","","",24.1,27.8,29.5,26.1,31.6,40.3,32.1,28.3,"Not Found","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q8N726","Tumor suppressor ARF OS=Homo sapiens OX=9606 GN=CDKN2A PE=1 SV=2",0,8.24,13,1,1,1,132,13.9,12.41,3.59,1,"cell death;cell division;cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus","cytoplasm;cytosol;mitochondrion;nucleus","catalytic activity;DNA binding;enzyme regulator activity;protein binding;RNA binding","Pf07392","1029","ENSG00000147889.17","CDKN2A","9","","Regulation of TP53 Degradation; Stabilization of p53; Regulation of RUNX3 expression and activity; SUMOylation of transcription factors; Oncogene Induced Senescence; SUMOylation of DNA damage response and repair proteins; Oxidative Stress Induced Senescence","TP53 Network; Cell Cycle; Signaling Pathways in Glioblastoma; Apoptosis; Bladder Cancer; G1 to S cell cycle control; Senescence and Autophagy in Cancer",33,0,1.092,0.13,0.486939518251187,0.981959010756837,"",156.6,143.4,"",3.01,4.77,"","","",31.3,33.3,32.2,33.4,29.3,28.7,31.9,30.7,"","","",25,25.2,25.6,24.2,21.1,28.7,26,24.5,"Not Found","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q16600","Zinc finger protein 239 OS=Homo sapiens OX=9606 GN=ZNF239 PE=1 SV=3",0,8.158,5,2,2,2,458,51.6,7.64,5.89,2,"metabolic process;regulation of biological process","nucleus","DNA binding;metal ion binding;protein binding;RNA binding","Pf00096, Pf13465","8187","ENSG00000196793.13","ZNF239","10","","","",0,0,1.06,0.08,0.490600080053219,0.981959010756837,227.6,37.2,35.1,131.99,5.86,7.53,333.1,9659,"",280.8,306.8,277.3,310.5,267.7,282.2,271.5,314.8,16.9,2.7,"",224.1,232.2,220.2,224.9,192.8,282.2,221.3,251.2,"High","High","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q9UBL3","Set1/Ash2 histone methyltransferase complex subunit ASH2 OS=Homo sapiens OX=9606 GN=ASH2L PE=1 SV=1",0,102.15,32,16,25,16,628,68.7,5.69,83.92,16,"cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus","nucleus","catalytic activity;DNA binding;metal ion binding;protein binding","Pf00622","9070","ENSG00000129691.15","ASH2L","8","","Deactivation of the beta-catenin transactivating complex; RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function; PKMTs methylate histone lysines; Activation of anterior HOX genes in hindbrain development during early embryogenesis; Formation of the beta-catenin:TCF transactivating complex","",16,0,0.955,-0.07,0.51165008191262,0.982168814739206,115.6,90.1,94.3,35.17,3.15,6.87,4304.6,7154.8,"",4383.7,4264,4436.9,4132,4133.8,4461.3,4593.3,4881.6,218.4,2,"",3498.2,3227.4,3523.3,2992.6,2977.3,4461.3,3743.6,3895.4,"High","High","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P41743","Protein kinase C iota type OS=Homo sapiens OX=9606 GN=PRKCI PE=1 SV=2",0,41.577,16,8,12,8,596,68.2,5.85,31.3,8,"cell organization and biogenesis;cellular component movement;metabolic process;regulation of biological process;response to stimulus;transport","cytoplasm;cytoskeleton;cytosol;endosome;membrane;nucleus","catalytic activity;metal ion binding;nucleotide binding;protein binding","Pf00069, Pf00130, Pf00433, Pf00564, Pf07714, Pf14531","5584","ENSG00000163558.12","PRKCI","3","Hippo signaling pathway; Tight junction; Rap1 signaling pathway; Insulin signaling pathway; Endocytosis; Platelet activation","Tight junction interactions; Signalling by NGF; p75NTR recruits signalling complexes","miRs in Muscle Cell Differentiation; Signaling Pathways in Glioblastoma; Corticotropin-releasing hormone signaling pathway; G Protein Signaling Pathways; VEGFA-VEGFR2 Signaling Pathway; Wnt Signaling Pathway and Pluripotency; Wnt Signaling Pathway; EGF/EGFR Signaling Pathway; Insulin Signaling",25,0,0.962,-0.06,0.506946603314263,0.982168814739206,99.6,98.3,102.1,"",3.56,1.47,1754.2,"","",1738.1,1754.9,1723.3,1619.9,1771.9,1817.8,1823.4,1778.8,89,"","",1387,1328.3,1368.5,1173.2,1276.2,1817.8,1486.1,1419.4,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q96E09","Protein FAM122A OS=Homo sapiens OX=9606 GN=FAM122A PE=1 SV=1",0,14.393,19,3,4,3,287,30.5,6.79,11.53,3,"","","protein binding","","116224","","FAM122A","9","","","",0,0,0.908,-0.14,0.50539739247204,0.982168814739206,"",142.8,157.2,"",20.53,16.36,"","","",18.3,18,26.8,19.1,24.7,16.6,21.3,19.8,"","","",14.6,13.6,21.3,13.8,17.8,16.6,17.4,15.8,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q15459","Splicing factor 3A subunit 1 OS=Homo sapiens OX=9606 GN=SF3A1 PE=1 SV=1",0,274.69,39,32,77,32,793,88.8,5.22,270.48,32,"cell organization and biogenesis;metabolic process;regulation of biological process","nucleus;spliceosomal complex","protein binding;RNA binding","Pf00240, Pf01805, Pf12230, Pf14560","10291","ENSG00000099995.18","SF3A1","22","Spliceosome","mRNA Splicing - Major Pathway","mRNA Processing",6,0,0.96,-0.06,0.512203932544019,0.982496516897987,135.1,80.8,84.1,66.34,1.84,1.36,9695.3,26830.6,"",9576.9,9540.2,9705.4,9934.8,10033.6,10042.5,10016.1,10303.8,491.9,7.5,"",7642.4,7221,7707,7195.2,7226.5,10042.5,8163.2,8222.2,"High","High","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q92609","TBC1 domain family member 5 OS=Homo sapiens OX=9606 GN=TBC1D5 PE=1 SV=1",0,55.797,23,12,13,12,795,88.9,6.54,48.21,12,"cell communication;metabolic process;regulation of biological process;response to stimulus;transport","cytosol;endosome;Golgi;membrane;vacuole","enzyme regulator activity;protein binding","Pf00566","9779","ENSG00000131374.14","TBC1D5","3","","","",0,0,1.058,0.08,0.514460534404245,0.983574223698078,83.6,111.3,105.1,"",4.05,4.12,214.8,"","",281.5,290.5,298.7,271.9,259.9,272.6,267.8,286.6,10.9,"","",224.6,219.9,237.2,196.9,187.2,272.6,218.3,228.7,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q6UXD5-5","Isoform 5 of Seizure 6-like protein 2 OS=Homo sapiens OX=9606 GN=SEZ6L2",0,54.083,14,9,13,9,879,94.4,4.92,39.86,9,"","membrane","","Pf00084, Pf00431","26470","ENSG00000174938.14","SEZ6L2","16","","","",0,0,0.952,-0.07,0.517670199228808,0.983704903371516,99.6,97.7,102.7,"",6.9,5.3,955.9,"","",910.5,897.6,965.8,1042.2,963.2,903.7,1007.5,1016.6,48.5,"","",726.6,679.4,766.9,754.8,693.7,903.7,821.1,811.2,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q13625","Apoptosis-stimulating of p53 protein 2 OS=Homo sapiens OX=9606 GN=TP53BP2 PE=1 SV=2",0,53.474,13,11,13,10,1128,125.5,6.07,42.15,11,"cell death;metabolic process;regulation of biological process;response to stimulus","cytoplasm;mitochondrion;nucleus","protein binding","Pf00018, Pf00023, Pf04111, Pf04156, Pf06785, Pf07653, Pf12252, Pf12796, Pf13606, Pf13637, Pf13857, Pf14604, Pf15548","7159","","TP53BP2","1","Hippo signaling pathway","Regulation of TP53 Activity through Association with Co-factors; TP53 Regulates Transcription of Death Receptors and Ligands; TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain; TP53 Regulates Transcription of Genes Involved in Cytochrome C Release; Activation of PUMA and translocation to mitochondria","",16,1,0.951,-0.07,0.519010771799654,0.98380997719812,94.4,100.2,105.4,"",1.32,1.13,857.4,"","",909.8,909.4,933,907.7,955.5,955.9,978,957.4,43.5,"","",726,688.3,740.9,657.4,688.2,955.9,797.1,764,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q99594","Transcriptional enhancer factor TEF-5 OS=Homo sapiens OX=9606 GN=TEAD3 PE=1 SV=2",0,17.938,11,5,7,1,435,48.6,8.4,20.41,5,"cell division;metabolic process;regulation of biological process;response to stimulus","nucleus","DNA binding;protein binding","Pf01285","7005","ENSG00000007866.19","TEAD3","6","Hippo signaling pathway; Hippo signaling pathway -multiple species","YAP1- and WWTR1 (TAZ)-stimulated gene expression; PPARA activates gene expression; RUNX3 regulates YAP1-mediated transcription","",12,0,0.925,-0.11,0.521439471429915,0.984697934050014,74.8,108.2,117,"",2.03,10.24,104.5,"","",149.4,150.2,151.9,156.3,184.8,171.9,147.1,155.3,5.3,"","",119.2,113.7,120.6,113.2,133.1,171.9,119.9,123.9,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q96QE2","Proton myo-inositol cotransporter OS=Homo sapiens OX=9606 GN=SLC2A13 PE=1 SV=3",0,20.674,8,5,5,5,648,70.3,5.96,15.76,5,"transport","membrane","transporter activity","Pf00083, Pf07690, Pf13347","114134","ENSG00000151229.12","SLC2A13","12","","Inositol transporters","NRF2 pathway",5,0,0.95,-0.07,0.523986991025808,0.986943187723919,106.2,94.4,99.4,"",3.68,7.31,518.4,"","",470,437.2,451.6,473.2,496.5,473.2,473.4,550.5,26.3,"","",375.1,330.9,358.6,342.7,357.6,473.2,385.8,439.3,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","O00159","Unconventional myosin-Ic OS=Homo sapiens OX=9606 GN=MYO1C PE=1 SV=4",0,225.417,37,42,61,41,1063,121.6,9.41,206.53,42,"cell organization and biogenesis;regulation of biological process;response to stimulus;transport","cytoplasm;cytosol;membrane;nucleus","catalytic activity;motor activity;nucleotide binding;protein binding","Pf00063, Pf06017","4641","ENSG00000197879.14","MYO1C","17","","Translocation of GLUT4 to the plasma membrane; Regulation of actin dynamics for phagocytic cup formation","Insulin Signaling",8,0,0.962,-0.06,0.531811750580451,0.987080435823287,128.1,84.3,87.6,68.34,2.74,1.89,6618.6,9659,23685,6030,6324.3,6395.3,6387,6626,6803,6584.4,6508,335.8,2.7,3,4812,4786.9,5078.5,4625.7,4772.2,6803,5366.4,5193.2,"High","High","High","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P98175-5","Isoform 5 of RNA-binding protein 10 OS=Homo sapiens OX=9606 GN=RBM10",0,159.127,36,33,48,31,995,110.3,6.28,157.63,33,"","","","","","","","","","","",0,2,0.965,-0.05,0.527625543465609,0.987080435823287,91.3,102.5,106.2,"",1.08,0.67,2406.6,"","",2738.8,2670.6,2710.6,2690.4,2801.8,2793.2,2762.2,2801.3,122.1,"","",2185.6,2021.4,2152.5,1948.5,2017.9,2793.2,2251.2,2235.4,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q99439","Calponin-2 OS=Homo sapiens OX=9606 GN=CNN2 PE=1 SV=4",0,112.68,53,15,32,13,309,33.7,7.33,91.33,15,"cell organization and biogenesis;regulation of biological process;response to stimulus;transport","cytoskeleton;extracellular;membrane;organelle lumen","protein binding","Pf00307, Pf00402","1265","ENSG00000064666.14","CNN2","19","","Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation; Neutrophil degranulation; Interleukin-12 family signaling","Myometrial Relaxation and Contraction Pathways",8,0,1.044,0.06,0.545623289831185,0.987080435823287,100.4,102,97.7,"",5.7,2.55,3374.3,"","",3430.4,3425.7,3164.7,3640.2,3360,3219.6,3202,3349.7,171.2,"","",2737.5,2592.9,2513.1,2636.4,2420,3219.6,2609.7,2673,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q9UBE0","SUMO-activating enzyme subunit 1 OS=Homo sapiens OX=9606 GN=SAE1 PE=1 SV=1",0,88.47,43,13,23,13,346,38.4,5.3,82.9,13,"metabolic process;regulation of biological process","cytoplasm;nucleus","catalytic activity;enzyme regulator activity;protein binding","Pf00899","10055","ENSG00000142230.11","SAE1","19","Ubiquitin mediated proteolysis","SUMO is conjugated to E1 (UBA2:SAE1); SUMO is transferred from E1 to E2 (UBE2I, UBC9)","",7,0,0.963,-0.05,0.558252937311649,0.987080435823287,97.6,99.3,103.1,"",6.45,4.44,3198.9,"","",3319,3193.9,3158.2,3629.7,3475,3155.3,3306.1,3454.1,162.3,"","",2648.6,2417.5,2507.9,2628.8,2502.8,3155.3,2694.5,2756.3,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P53675","Clathrin heavy chain 2 OS=Homo sapiens OX=9606 GN=CLTCL1 PE=1 SV=2",0,77.658,10,16,36,6,1640,186.9,5.85,96.66,16,"cell organization and biogenesis;regulation of biological process;response to stimulus;transport","cytosol;endosome;membrane","protein binding;signal transducer activity;structural molecule activity","Pf00637, Pf01394, Pf04053, Pf09268, Pf13838","8218","ENSG00000070371.15","CLTCL1","22","Endocrine and other factor-regulated calcium reabsorption; Synaptic vesicle cycle; Endocytosis; Bacterial invasion of epithelial cells; Huntington's disease; Lysosome","EPH-ephrin mediated repulsion of cells; Cargo recognition for clathrin-mediated endocytosis; Formation of annular gap junctions","Synaptic Vesicle Pathway",19,0,0.941,-0.09,0.557737397807961,0.987080435823287,57.4,117.6,125,"",12.11,4.38,84.8,"","",176.4,181.3,171.3,136.8,184.9,184.5,194.4,174.6,4.3,"","",140.8,137.2,136,99.1,133.2,184.5,158.4,139.3,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P25398","40S ribosomal protein S12 OS=Homo sapiens OX=9606 GN=RPS12 PE=1 SV=3",0,68.051,55,8,42,8,132,14.5,7.21,108.7,8,"cell organization and biogenesis;metabolic process;transport","cytoplasm;cytosol;membrane;ribosome","RNA binding;structural molecule activity","Pf01248","6206","ENSG00000112306.7","RPS12","6","Ribosome","Peptide chain elongation; Eukaryotic Translation Termination; Viral mRNA Translation; Formation of the ternary complex, and subsequently, the 43S complex; L13a-mediated translational silencing of Ceruloplasmin expression; Selenocysteine synthesis; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); GTP hydrolysis and joining of the 60S ribosomal subunit; Ribosomal scanning and start codon recognition; Major pathway of rRNA processing in the nucleolus and cytosol; Regulation of expression of SLITs and ROBOs; Translation initiation complex formation; Formation of a pool of free 40S subunits; SRP-dependent cotranslational protein targeting to membrane","Cytoplasmic Ribosomal Proteins",38,0,1.039,0.05,0.551416898423191,0.987080435823287,205.4,48.2,46.4,60.83,3.33,1.33,5339.4,23968.7,24474.5,5789.4,5682.6,5560.4,5355.1,5513.1,5362.6,5453.8,5369.6,270.9,6.7,3.1,4620,4301.2,4415.5,3878.4,3970.7,5362.6,4444.9,4284.8,"High","High","High","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q9HD15","Steroid receptor RNA activator 1 OS=Homo sapiens OX=9606 GN=SRA1 PE=1 SV=1",0,59.801,37,10,13,10,236,25.7,7.03,35.98,10,"cell death;cell differentiation;cell proliferation;metabolic process;regulation of biological process","cytoplasm;cytoskeleton;cytosol;membrane;nucleus","protein binding;RNA binding","Pf07304","10011","ENSG00000213523.10","SRA1","5","","","",0,0,1.057,0.08,0.535865007699071,0.987080435823287,113.3,95.9,90.7,"",5.59,9.22,2625.4,"","",2337.8,2269.4,2175.2,2052.9,1923,1955.6,2258.4,2290.2,133.2,"","",1865.6,1717.7,1727.3,1486.8,1385,1955.6,1840.6,1827.5,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q8IWA0","WD repeat-containing protein 75 OS=Homo sapiens OX=9606 GN=WDR75 PE=1 SV=1",0,53.401,18,14,14,14,830,94.4,5.96,45.17,14,"metabolic process;regulation of biological process","nucleus","protein binding;RNA binding","Pf00400","84128","ENSG00000115368.9","WDR75","2","Ribosome biogenesis in eukaryotes","Major pathway of rRNA processing in the nucleolus and cytosol; rRNA modification in the nucleus and cytosol","",6,0,1.041,0.06,0.570825221392404,0.987080435823287,200.2,50.9,48.9,124.45,6.44,6.93,1511.7,"",23685,1510.5,1532.3,1608,1375.2,1554.9,1519.3,1406.6,1336.8,76.7,"",3,1205.4,1159.8,1276.9,996,1119.9,1519.3,1146.4,1066.7,"High","Not Found","High","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P31751","RAC-beta serine/threonine-protein kinase OS=Homo sapiens OX=9606 GN=AKT2 PE=1 SV=2",0,44.119,25,10,11,9,481,55.7,6.37,30.12,10,"cell death;cell differentiation;cell organization and biogenesis;development;metabolic process;regulation of biological process;response to stimulus;transport","cytoplasm;cytosol;endosome;membrane;nucleus","catalytic activity;metal ion binding;nucleotide binding;protein binding","Pf00069, Pf00169, Pf00433, Pf07714, Pf14531, Pf15413","208","ENSG00000105221.16","AKT2","19","HIF-1 signaling pathway; MAPK signaling pathway; HTLV-I infection; Hepatitis C; Platinum drug resistance; Osteoclast differentiation; Acute myeloid leukemia; Tuberculosis; Measles; Adipocytokine signaling pathway; Dopaminergic synapse; Chronic myeloid leukemia; Thyroid hormone signaling pathway; AMPK signaling pathway; Influenza A; FoxO signaling pathway; Colorectal cancer; Focal adhesion; Endocrine resistance; Hepatitis B; Non-small cell lung cancer; Melanoma; Toll-like receptor signaling pathway; PI3K-Akt signaling pathway; T cell receptor signaling pathway; B cell receptor signaling pathway; AGE-RAGE signaling pathway in diabetic complications; Non-alcoholic fatty liver disease (NAFLD); Insulin resistance; Phospholipase D signaling pathway; Pathways in cancer; Proteoglycans in cancer; Signaling pathways regulating pluripotency of stem cells; Central carbon metabolism in cancer; Endometrial cancer; Toxoplasmosis; Ras signaling pathway; Chagas disease (American trypanosomiasis); Epstein-Barr virus infection; Glioma; mTOR signaling pathway; Estrogen signaling pathway; Insulin signaling pathway; Progesterone-mediated oocyte maturation; EGFR tyrosine kinase inhibitor resistance; Fc epsilon RI signaling pathway; Platelet activation; cGMP-PKG signaling pathway; Prostate cancer; Choline metabolism in cancer; cAMP signaling pathway; Tight junction; Rap1 signaling pathway; Glucagon signaling pathway; Small cell lung cancer; Longevity regulating pathway; Prolactin signaling pathway; ErbB signaling pathway; Jak-STAT signaling pathway; Chemokine signaling pathway; TNF signaling pathway; VEGF signaling pathway; Renal cell carcinoma; Sphingolipid signaling pathway; Cholinergic synapse; Pancreatic cancer; Breast cancer; Apoptosis; Fc gamma R-mediated phagocytosis; Longevity regulating pathway - multiple species; Neurotrophin signaling pathway; Adrenergic signaling in cardiomyocytes; Carbohydrate digestion and absorption; Regulation of lipolysis in adipocytes","Regulation of PTEN stability and activity; Activation of AKT2; CTLA4 inhibitory signaling; G beta:gamma signalling through PI3Kgamma; Translocation of GLUT4 to the plasma membrane; AKT phosphorylates targets in the nucleus; Inhibition of TSC complex formation by PKB; AKT phosphorylates targets in the cytosol; Regulation of TP53 Activity through Association with Co-factors; Regulation of TP53 Activity through Acetylation; Regulation of TP53 Degradation; Negative regulation of the PI3K/AKT network; Activation of BAD and translocation to mitochondria ; RAB GEFs exchange GTP for GDP on RABs; Constitutive Signaling by AKT1 E17K in Cancer; Downregulation of ERBB2:ERBB3 signaling; Deactivation of the beta-catenin transactivating complex; Cyclin E associated events during G1/S transition ; GPVI-mediated activation cascade; CD28 dependent PI3K/Akt signaling; VEGFR2 mediated vascular permeability; AKT-mediated inactivation of FOXO1A; PDE3B signalling; RUNX2 regulates genes involved in cell migration; TP53 Regulates Metabolic Genes","AMP-activated Protein Kinase (AMPK) Signaling; Regulation of toll-like receptor signaling pathway; MicroRNAs in cardiomyocyte hypertrophy; TFs Regulate miRNAs related to cardiac hypertrophy; Integrin-mediated Cell Adhesion; RANKL/RANK (Receptor activator of NFKB (ligand)) Signaling Pathway; TNF related weak inducer of apoptosis (TWEAK) Signaling Pathway; Signaling Pathways in Glioblastoma; Signal Transduction of S1P Receptor; Cardiac Hypertrophic Response; Focal Adhesion; MAPK Signaling Pathway; Angiopoietin Like Protein 8 Regulatory Pathway; Chemokine signaling pathway; ESC Pluripotency Pathways; Focal Adhesion-PI3K-Akt-mTOR-signaling pathway; Insulin Signaling; Toll-like receptor signaling pathway",170,1,1.044,0.06,0.566643220239873,0.987080435823287,93.8,105.3,100.9,"",3.33,2.42,1182.6,"","",1336.7,1395.4,1319,1289.9,1295.6,1248.5,1302.2,1243.4,60,"","",1066.7,1056.2,1047.4,934.2,933.1,1248.5,1061.3,992.2,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","O15050","TPR and ankyrin repeat-containing protein 1 OS=Homo sapiens OX=9606 GN=TRANK1 PE=2 SV=4",0,36.744,4,10,10,10,2925,336,6.76,28.95,10,"","","protein binding","Pf12796, Pf13414","9881","ENSG00000168016.13","TRANK1","3","","","",0,0,0.953,-0.07,0.570578689677787,0.987080435823287,91.1,101.9,106.9,"",2.68,3.23,325.2,"","",351.3,362.7,375,364.8,365.7,379.4,383.9,395.5,16.5,"","",280.3,274.5,297.8,264.2,263.4,379.4,312.9,315.6,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q16774-2","Isoform 2 of Guanylate kinase OS=Homo sapiens OX=9606 GN=GUK1",0,32.054,33,7,12,7,218,23.8,7.5,34.73,7,"metabolic process;transport","cytosol","catalytic activity;nucleotide binding;RNA binding","Pf00005, Pf00625, Pf00910, Pf01926, Pf03193, Pf05729, Pf13173, Pf13191, Pf13207, Pf13401, Pf13521, Pf13555, Pf13671","2987","ENSG00000143774.16","GUK1","1","","","",0,0,1.056,0.08,0.541255975434067,0.987080435823287,90.5,107.6,101.9,"",4.2,2.68,934.2,"","",1093.5,1129.1,1088.9,1191.2,1090.6,1023.3,1044.8,1059.4,47.4,"","",872.6,854.6,864.7,862.7,785.5,1023.3,851.5,845.4,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","O95900","Mitochondrial mRNA pseudouridine synthase TRUB2 OS=Homo sapiens OX=9606 GN=TRUB2 PE=1 SV=1",0,27.384,27,7,8,7,331,36.7,8.98,23.01,7,"metabolic process","cytosol;mitochondrion;organelle lumen","catalytic activity;RNA binding","Pf01509","26995","ENSG00000167112.9","TRUB2","9","","","",0,0,0.95,-0.07,0.539971193417047,0.987080435823287,102.3,96.3,101.4,"",1.18,2.22,818,"","",763.9,783.1,774.7,764.5,840.2,815.4,799.4,804.8,41.5,"","",609.6,592.7,615.2,553.7,605.1,815.4,651.5,642.2,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q8N2W9","E3 SUMO-protein ligase PIAS4 OS=Homo sapiens OX=9606 GN=PIAS4 PE=1 SV=1",0,22.821,12,4,5,4,510,56.5,6.14,18.37,4,"metabolic process;regulation of biological process;response to stimulus","cytoplasm;nucleus","catalytic activity;DNA binding;metal ion binding;protein binding","Pf02037, Pf02891, Pf11789, Pf14324","51588","ENSG00000105229.6","PIAS4","19","Ubiquitin mediated proteolysis; Jak-STAT signaling pathway; NF-kappa B signaling pathway","G2/M DNA damage checkpoint; Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks; SUMOylation of transcription factors; Processing of DNA double-strand break ends; SUMOylation of DNA replication proteins; Nonhomologous End-Joining (NHEJ); SUMOylation of DNA damage response and repair proteins","Androgen receptor signaling pathway",23,0,0.952,-0.07,0.565682179756606,0.987080435823287,100.6,97.2,102.2,"",5.36,5.31,360.7,"","",334.2,363.3,367.2,331.8,358.1,374.5,390.3,345.5,18.3,"","",266.7,275,291.6,240.3,257.9,374.5,318.1,275.7,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","O94967","WD repeat-containing protein 47 OS=Homo sapiens OX=9606 GN=WDR47 PE=1 SV=1",0,20.4,9,7,8,7,919,101.9,5.94,21.01,7,"development","cytoplasm;cytoskeleton","protein binding","Pf00400","22911","ENSG00000085433.15","WDR47","1","","","",0,0,0.947,-0.08,0.556610135650986,0.987080435823287,87.8,103.2,109,"",3.88,5.01,333.1,"","",400.2,390.7,392.6,365.6,450.3,418.5,403.3,408.5,16.9,"","",319.4,295.7,311.8,264.8,324.3,418.5,328.7,326,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P62330","ADP-ribosylation factor 6 OS=Homo sapiens OX=9606 GN=ARF6 PE=1 SV=2",0,17.681,29,3,3,3,175,20.1,8.95,8.17,3,"cell death;cell differentiation;cell division;cell organization and biogenesis;cellular component movement;regulation of biological process;response to stimulus;transport","cytoplasm;cytosol;endosome;Golgi;membrane","catalytic activity;enzyme regulator activity;nucleotide binding;protein binding;signal transducer activity","Pf00025, Pf00071, Pf00503, Pf04670, Pf08477, Pf09439","382","ENSG00000165527.6","ARF6","14","Ras signaling pathway; Endocytosis; Fc gamma R-mediated phagocytosis; Phospholipase D signaling pathway","MET receptor recycling; TBC/RABGAPs; Clathrin-mediated endocytosis","VEGFA-VEGFR2 Signaling Pathway; EGF/EGFR Signaling Pathway; Insulin Signaling",16,0,0.967,-0.05,0.567991452203192,0.987080435823287,103.2,96.8,100.1,"",3.44,4.29,1107.7,"","",1108,1039.9,1029.9,1038.1,1054.8,1077.9,1071,1159.6,56.2,"","",884.2,787.1,817.8,751.8,759.7,1077.9,872.9,925.3,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q7Z4L5","Tetratricopeptide repeat protein 21B OS=Homo sapiens OX=9606 GN=TTC21B PE=1 SV=2",0,15.588,4,5,5,5,1316,150.8,6.96,9.88,5,"cellular component movement;regulation of biological process;response to stimulus;transport","cytoplasm;cytoskeleton","protein binding","Pf12895, Pf13414, Pf14559","79809","ENSG00000123607.14","TTC21B","2","","Hedgehog 'off' state; Intraflagellar transport","",6,0,0.93,-0.11,0.554739417188961,0.987080435823287,79.2,106.4,114.4,"",8.23,9.79,96.6,"","",130.3,150.3,129.2,126.2,150,129.9,125.8,152.5,4.9,"","",104,113.8,102.6,91.4,108,129.9,102.5,121.7,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q8IVB5","LIX1-like protein OS=Homo sapiens OX=9606 GN=LIX1L PE=2 SV=1",0,11.824,12,5,6,5,337,36.5,8.56,14.7,5,"cell organization and biogenesis","cytoplasm","","Pf14954","128077","ENSG00000271601.3","LIX1L; LOC101060547","1","","","",0,0,1.059,0.08,0.540111201242293,0.987080435823287,102,101.8,96.2,"",8.91,12.51,333.1,"","",315.9,312.2,375.9,349.7,318.2,299.9,390.4,309.8,16.9,"","",252.1,236.3,298.5,253.3,229.2,299.9,318.2,247.2,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q9NPB8","Glycerophosphocholine phosphodiesterase GPCPD1 OS=Homo sapiens OX=9606 GN=GPCPD1 PE=1 SV=2",0,9.131,5,3,3,3,672,76,5.53,7.38,3,"cellular homeostasis;metabolic process","cytoplasm;cytosol","catalytic activity","Pf00686, Pf03009","56261","ENSG00000125772.12","GPCPD1","20","Glycerophospholipid metabolism; Choline metabolism in cancer","Hydrolysis of LPC; Hydrolysis of LPE","",8,0,1.061,0.09,0.531026145646633,0.987080435823287,104.4,100.7,94.9,"",23.14,12.27,65,"","",71.3,55.6,70.8,42.3,56.2,57.6,72.9,60.7,3.3,"","",56.9,42.1,56.2,30.6,40.5,57.6,59.4,48.4,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q9NWS8","Required for meiotic nuclear division protein 1 homolog OS=Homo sapiens OX=9606 GN=RMND1 PE=1 SV=2",0,6.511,4,2,2,2,449,51.6,8.69,6.03,2,"metabolic process;regulation of biological process","mitochondrion","protein binding","Pf02582","55005","ENSG00000155906.16","RMND1","6","","","",0,0,1.058,0.08,0.564398610595926,0.987080435823287,114.9,95.2,90,"",2.84,6.74,496.7,"","",404.3,397,418.8,421.3,376.5,371.6,402,429.5,25.2,"","",322.6,300.5,332.6,305.1,271.2,371.6,327.6,342.7,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P68402","Platelet-activating factor acetylhydrolase IB subunit beta OS=Homo sapiens OX=9606 GN=PAFAH1B2 PE=1 SV=1",1E-3,4.466,4,1,3,1,229,25.6,5.92,7.46,1,"metabolic process;regulation of biological process;transport","cytoplasm;cytosol;extracellular;membrane;organelle lumen","catalytic activity;protein binding","Pf00657, Pf13472","5049","ENSG00000168092.13","PAFAH1B2","11","Ether lipid metabolism; Metabolic pathways","COPI-independent Golgi-to-ER retrograde traffic; Neutrophil degranulation","",10,0,1.046,0.07,0.540615606408158,0.987080435823287,113.6,95.3,91.1,"",3.96,3.38,863.3,"","",675.2,735.4,713.1,735.1,711.7,671.6,672.9,713.8,43.8,"","",538.8,556.6,566.3,532.4,512.6,671.6,548.4,569.6,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q9D2A5","Cyclic AMP-responsive element-binding protein 3-like protein 4 OS=Mus musculus OX=10090 GN=Creb3l4 PE=1 SV=1",0.006,2.713,2,1,1,1,370,41,6.7,2.5,1,"cell differentiation;cell organization and biogenesis;development;metabolic process;regulation of biological process;reproduction;response to stimulus","cytoplasm;cytosol;endoplasmic reticulum;Golgi;membrane;mitochondrion;nucleus","DNA binding","Pf00170, Pf03131, Pf06005, Pf07716","78284","ENSMUSG00000027938.11","Creb3l4","3","Huntington's disease; Melanogenesis; Viral carcinogenesis; Cholinergic synapse; Aldosterone synthesis and secretion; Alcoholism; Thyroid hormone synthesis; Prostate cancer; Amphetamine addiction; Estrogen signaling pathway; cAMP signaling pathway; Cocaine addiction; Dopaminergic synapse; Vasopressin-regulated water reabsorption; Longevity regulating pathway; AMPK signaling pathway; Hepatitis B; Adrenergic signaling in cardiomyocytes; PI3K-Akt signaling pathway; Insulin resistance; Glucagon signaling pathway; cGMP-PKG signaling pathway; TNF signaling pathway; Insulin secretion","","Focal Adhesion-PI3K-Akt-mTOR-signaling pathway",25,0,0.931,-0.1,0.553020473116461,0.987080435823287,71.1,110.4,118.5,"",12.35,8.71,39.4,"","",58.3,64.3,68.4,51.2,66.5,65,67.4,55.4,2,"","",46.5,48.7,54.3,37.1,47.9,65,54.9,44.2,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q6KB66","Keratin, type II cytoskeletal 80 OS=Homo sapiens OX=9606 GN=KRT80 PE=1 SV=2",0,75.571,49,21,25,1,452,50.5,5.67,70.1,21,"cell death;regulation of biological process;transport","cytoplasm;cytoskeleton;cytosol","protein binding;structural molecule activity;transporter activity","Pf00038, Pf01496, Pf05557, Pf12128, Pf13166","144501","ENSG00000167767.13","KRT80","12","","Formation of the cornified envelope","",3,14,0.963,-0.05,0.571825643029147,0.987803433833412,154.3,71.5,74.2,96.03,5.77,6.24,2867.8,"",15000.5,2959.3,3116.4,2911.2,3304.1,2955.3,3156,3148.9,3436.6,145.5,"",1.9,2361.5,2358.8,2311.8,2393,2128.5,3156,2566.4,2742.3,"Not Found","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","O43314","Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2 OS=Homo sapiens OX=9606 GN=PPIP5K2 PE=1 SV=3",0,107.002,22,23,25,17,1243,140.3,8.22,88.91,23,"metabolic process","cytoplasm;cytosol","catalytic activity;nucleotide binding","Pf00328, Pf08443","23262","ENSG00000145725.19","PPIP5K2","5","Phosphatidylinositol signaling system","Synthesis of pyrophosphates in the cytosol","",4,4,1.053,0.07,0.574835777752879,0.990184887787363,95.4,104.9,99.7,"",6.87,1.62,2294.2,"","",2549.9,2497.7,2584.8,2213.6,2394,2400.5,2460.5,2368,116.4,"","",2034.8,1890.5,2052.6,1603.2,1724.2,2400.5,2005.3,1889.6,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q05048","Cleavage stimulation factor subunit 1 OS=Homo sapiens OX=9606 GN=CSTF1 PE=1 SV=1",0,95.427,42,15,29,15,431,48.3,6.58,90.58,15,"metabolic process","nucleus","protein binding;RNA binding","Pf00400, Pf11768","1477","ENSG00000101138.11","CSTF1","20","mRNA surveillance pathway","Cleavage of Growing Transcript in the Termination Region ; Processing of Intronless Pre-mRNAs; mRNA 3'-end processing; mRNA Splicing - Major Pathway","mRNA Processing",13,0,0.969,-0.05,0.58104786621849,0.990465901168026,101.8,97.5,100.7,"",0.89,2.62,3066.9,"","",2954,2919.8,2971.9,2918.6,3185.2,3033.9,3028.5,3014,155.6,"","",2357.3,2210,2360,2113.8,2294.1,3033.9,2468.3,2405.1,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q86Y39","NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 11 OS=Homo sapiens OX=9606 GN=NDUFA11 PE=1 SV=3",0,32.748,59,5,6,5,141,14.8,8.72,22.72,5,"cell organization and biogenesis;metabolic process;transport","membrane;mitochondrion","catalytic activity","","126328","ENSG00000174886.12","NDUFA11","19","Non-alcoholic fatty liver disease (NAFLD); Alzheimer's disease; Huntington's disease; Metabolic pathways; Oxidative phosphorylation; Parkinson's disease","Complex I biogenesis","Oxidative phosphorylation",12,0,1.047,0.07,0.579069042065953,0.990465901168026,108.7,97.8,93.4,"",11.08,1.99,1109.7,"","",1013.2,983.6,1109.2,844.6,958.7,974.5,947.7,929.4,56.3,"","",808.5,744.5,880.8,611.7,690.5,974.5,772.4,741.6,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q86UY6","N-alpha-acetyltransferase 40 OS=Homo sapiens OX=9606 GN=NAA40 PE=1 SV=1",0,16.977,22,5,5,5,237,27.2,7.39,15.57,5,"cell organization and biogenesis;metabolic process","cytoplasm;nucleus","catalytic activity;protein binding","Pf00583","79829","ENSG00000110583.12","NAA40","11","","","Metapathway biotransformation",1,0,0.954,-0.07,0.578486284829564,0.990465901168026,99,98.1,102.9,"",8.8,9.7,839.6,"","",847.4,820.8,843.9,698.1,775.3,825.3,957.4,922.7,42.6,"","",676.2,621.3,670.1,505.6,558.4,825.3,780.3,736.3,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q6NUJ5","PWWP domain-containing protein 2B OS=Homo sapiens OX=9606 GN=PWWP2B PE=1 SV=3",0,10.799,5,2,3,2,590,63.9,8.21,7.3,2,"","","protein binding","Pf00855","170394","ENSG00000171813.13","PWWP2B","10","","","",0,0,1.044,0.06,0.582857917375272,0.990465901168026,118.1,92.9,89,"",5.81,12.41,153.7,"","",117.8,124.2,132.7,117.5,111.5,115,116.8,144.4,7.8,"","",94,94,105.4,85.1,80.3,115,95.2,115.2,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","O95214","Leptin receptor overlapping transcript-like 1 OS=Homo sapiens OX=9606 GN=LEPROTL1 PE=1 SV=2",0,6.054,11,1,1,1,131,14.4,5.9,4.63,1,"regulation of biological process;transport","endosome;membrane","protein binding","Pf04133","23484","ENSG00000104660.17","LEPROTL1","8","","","",0,0,1.068,0.09,0.582035404332295,0.990465901168026,298.6,0.7,0.7,"",11.56,3.73,"","",11842.5,29.7,26.2,23,29.4,25,26.2,25.8,27.3,"","",1.5,23.7,19.8,18.3,21.3,18,26.2,21,21.8,"Not Found","Not Found","High","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q12907","Vesicular integral-membrane protein VIP36 OS=Homo sapiens OX=9606 GN=LMAN2 PE=1 SV=1",0,73.42,36,13,22,13,356,40.2,6.95,73.35,13,"regulation of biological process;transport","cell surface;endoplasmic reticulum;Golgi;membrane","metal ion binding;protein binding","Pf03388","10960","ENSG00000169223.14","LMAN2","5","Protein processing in endoplasmic reticulum","Cargo concentration in the ER; COPII (Coat Protein 2) Mediated Vesicle Transport","",10,0,1.044,0.06,0.588310737517139,0.992298142099313,153.4,74.9,71.8,86.9,0.73,4.25,2990,12520.9,"",2978.3,3023.8,2977,2997.6,3073.9,2873.8,2788.8,2852.1,151.7,3.5,"",2376.7,2288.7,2364,2171,2213.9,2873.8,2272.9,2275.9,"High","High","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P41208","Centrin-2 OS=Homo sapiens OX=9606 GN=CETN2 PE=1 SV=1",0,20.658,33,7,8,7,172,19.7,5,22.26,7,"cell division;cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus","cytoplasm;cytoskeleton;cytosol;nucleus","metal ion binding;protein binding","Pf00036, Pf13202, Pf13405, Pf13499, Pf13833","1069","ENSG00000147400.8","CETN2","X","Nucleotide excision repair","Regulation of PLK1 Activity at G2/M Transition; AURKA Activation by TPX2; Anchoring of the basal body to the plasma membrane; Recruitment of NuMA to mitotic centrosomes; Recruitment of mitotic centrosome proteins and complexes; Loss of Nlp from mitotic centrosomes; Formation of Incision Complex in GG-NER; DNA Damage Recognition in GG-NER; SUMOylation of DNA damage response and repair proteins","",27,0,0.971,-0.04,0.589997851689244,0.992298142099313,95.4,100.8,103.8,"",4.98,6.25,1691.1,"","",1776.9,1798.9,1625,1814.6,1968.8,1871,1812.6,1694,85.8,"","",1418,1361.6,1290.4,1314.2,1418,1871,1477.3,1351.8,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q15154-5","Isoform 5 of Pericentriolar material 1 protein OS=Homo sapiens OX=9606 GN=PCM1",0,181.867,24,44,50,44,2016,227.6,5.03,152.26,44,"","","","","","","","","","","",0,0,0.966,-0.05,0.59313137921619,0.992404137603925,138.8,79.2,82,63.38,1.26,1.85,5725.7,15025.1,"",5316.1,5410.5,5271.4,5265.6,5497.6,5458.3,5561.9,5322.6,290.5,4.2,"",4242.3,4095.2,4186,3813.6,3959.5,5458.3,4533,4247.3,"High","High","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q9Y2B0","Protein canopy homolog 2 OS=Homo sapiens OX=9606 GN=CNPY2 PE=1 SV=1",0,62.013,45,9,27,9,182,20.6,4.92,73.94,9,"regulation of biological process;response to stimulus","endoplasmic reticulum","protein binding","Pf11938","10330","ENSG00000257727.5","CNPY2","12","","","",0,0,1.049,0.07,0.599384092722863,0.992404137603925,97.9,103.5,98.6,"",5.55,3.51,1957.2,"","",2188.7,2013.6,2123.7,1931,1887.7,2037.8,2009.4,1932.4,99.3,"","",1746.6,1524.1,1686.4,1398.5,1359.6,2037.8,1637.7,1542,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","O95628","CCR4-NOT transcription complex subunit 4 OS=Homo sapiens OX=9606 GN=CNOT4 PE=1 SV=3",0,34.573,16,6,6,6,575,63.5,7.03,24.36,6,"metabolic process;regulation of biological process;response to stimulus","cytoplasm;cytosol;nucleus","catalytic activity;metal ion binding;protein binding;RNA binding","Pf00076, Pf13639, Pf13893, Pf13920, Pf13923, Pf14259, Pf14570","4850","ENSG00000080802.18","CNOT4","7","RNA degradation","TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain; Deadenylation of mRNA","",10,0,0.938,-0.09,0.597705288277193,0.992404137603925,"",145.2,154.8,"",6.95,9.39,"","","",146.5,125.4,141.3,131.7,136.2,155.4,159.1,131.7,"","","",116.9,94.9,112.2,95.4,98.1,155.4,129.7,105.1,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q8TCZ2","CD99 antigen-like protein 2 OS=Homo sapiens OX=9606 GN=CD99L2 PE=1 SV=1",0,20.228,16,3,4,3,262,28,5.14,13.15,3,"","membrane","protein binding","Pf12301, Pf13840","83692","ENSG00000102181.20","CD99L2","X","","Cell surface interactions at the vascular wall","",2,0,1.049,0.07,0.595749697272016,0.992404137603925,106.4,99.1,94.5,"",6.45,16.39,1155,"","",1077.1,1004.4,1075.4,1174.5,956.6,939.8,1101.1,1322.2,58.6,"","",859.5,760.2,854,850.6,689,939.8,897.4,1055.1,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P61009","Signal peptidase complex subunit 3 OS=Homo sapiens OX=9606 GN=SPCS3 PE=1 SV=1",0,20.193,27,5,9,5,180,20.3,8.62,21.13,5,"metabolic process;transport","endoplasmic reticulum;membrane","catalytic activity","Pf04573","60559","ENSG00000129128.12","SPCS3","4","Protein export","Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1); Synthesis, secretion, and deacylation of Ghrelin; SRP-dependent cotranslational protein targeting to membrane; Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)","",9,0,1.047,0.07,0.59882512919013,0.992404137603925,100.8,101.9,97.3,"",5.79,5.03,1052.5,"","",1027.6,1141.5,1102.3,1010.2,1086.6,1044.6,974.6,989.8,53.4,"","",820,864,875.3,731.6,782.6,1044.6,794.3,789.8,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","O15033","Apoptosis-resistant E3 ubiquitin protein ligase 1 OS=Homo sapiens OX=9606 GN=AREL1 PE=1 SV=3",0,9.76,2,2,2,2,823,94.2,7.25,5.5,2,"cell death;metabolic process;regulation of biological process","cytoplasm;cytosol","catalytic activity","Pf00630, Pf00632","9870","ENSG00000119682.16","AREL1; KIAA0317","14","","Antigen processing: Ubiquitination & Proteasome degradation","",4,0,1.044,0.06,0.59448427453786,0.992404137603925,97.8,103.3,98.9,"",6.08,4.88,153.7,"","",161.4,163.3,144.3,165.3,158,141.7,156.3,154.8,7.8,"","",128.8,123.6,114.6,119.7,113.8,141.7,127.4,123.5,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q96P16","Regulation of nuclear pre-mRNA domain-containing protein 1A OS=Homo sapiens OX=9606 GN=RPRD1A PE=1 SV=1",0,57.288,44,10,12,9,312,35.7,7.55,43.29,10,"metabolic process;regulation of biological process","","protein binding","Pf04818","55197","ENSG00000141425.17","RPRD1A","18","","RNA polymerase II transcribes snRNA genes","",3,0,1.037,0.05,0.603603970439008,0.992748816836941,186.3,57.9,55.8,120.03,2.66,3.54,1375.7,16813.8,"",1506.3,1446,1481.4,1540,1370.7,1424.6,1490.3,1455.9,69.8,4.7,"",1202,1094.5,1176.4,1115.3,987.2,1424.6,1214.6,1161.8,"High","High","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q13310-3","Isoform 3 of Polyadenylate-binding protein 4 OS=Homo sapiens OX=9606 GN=PABPC4",0,183.318,42,28,83,2,660,72.3,9.35,240.08,28,"coagulation;metabolic process","cytoplasm;cytosol;nucleus","protein binding;RNA binding","Pf00076, Pf00658, Pf13893, Pf14259","8761","ENSG00000090621.13","PABPC4","1","","","",0,18,1.032,0.05,0.607496054423943,0.99324284059106,98.7,102.2,99.1,"",0.4,1.07,6449.1,"","",6684.2,6682.3,6641.6,6706.2,6579.2,6452.3,6419.7,6503.3,327.2,"","",5334,5057.8,5274.1,4856.9,4738.5,6452.3,5232.1,5189.5,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P49773","Histidine triad nucleotide-binding protein 1 OS=Homo sapiens OX=9606 GN=HINT1 PE=1 SV=2",0,35.801,44,5,17,5,126,13.8,6.95,56.75,5,"cell death;metabolic process;regulation of biological process;response to stimulus","cytoplasm;cytoskeleton;cytosol;membrane;nucleus","catalytic activity;nucleotide binding;protein binding","Pf01230, Pf11969","3094","ENSG00000169567.11","HINT1","5","","","",0,0,1.033,0.05,0.609222561672339,0.99324284059106,107,98.1,94.9,"",3.05,3.23,4310.5,"","",4118.7,4011.9,3849.5,3895,3902.1,3761.9,3889.4,3641.2,218.7,"","",3286.7,3036.6,3056.9,2820.9,2810.4,3761.9,3169.9,2905.6,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P50135","Histamine N-methyltransferase OS=Homo sapiens OX=9606 GN=HNMT PE=1 SV=1",0,14.815,14,4,5,4,292,33.3,5.34,16.93,4,"metabolic process;response to stimulus","cytoplasm;cytosol","catalytic activity","Pf08242, Pf13489, Pf13847","3176","ENSG00000150540.13","HNMT","2","Histidine metabolism","Metabolism of ingested SeMet, Sec, MeSec into H2Se; Histidine catabolism","Amino Acid metabolism; Metapathway biotransformation; Methylation Pathways",10,0,0.958,-0.06,0.608201924632358,0.99324284059106,79.5,107.8,112.6,"",8.84,4.98,258.2,"","",404.5,351,330.9,349.2,398.5,368.9,356.9,362.4,13.1,"","",322.8,265.7,262.8,252.9,287,368.9,290.9,289.2,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q14678","KN motif and ankyrin repeat domain-containing protein 1 OS=Homo sapiens OX=9606 GN=KANK1 PE=1 SV=3",0,47.786,8,7,8,6,1352,147.2,5.3,28.61,7,"cell organization and biogenesis;metabolic process;regulation of biological process","cytoplasm;membrane;nucleus","protein binding","Pf00023, Pf05667, Pf10267, Pf12075, Pf12796, Pf13606, Pf13637, Pf13857","23189","ENSG00000107104.18","KANK1","9","","","",0,0,1.042,0.06,0.611540051375501,0.993621885764148,97.1,103.6,99.3,"",7.62,2.99,132.1,"","",141.2,140.4,142.8,120.8,140.9,136.5,131.5,133.7,6.7,"","",112.7,106.3,113.4,87.5,101.5,136.5,107.2,106.7,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q96BT7","Alkylated DNA repair protein alkB homolog 8 OS=Homo sapiens OX=9606 GN=ALKBH8 PE=1 SV=2",0,7.029,5,3,3,3,664,75.2,7.99,5.67,3,"metabolic process;response to stimulus","cytoplasm;cytosol;nucleus","catalytic activity;metal ion binding;protein binding;RNA binding","Pf01209, Pf03171, Pf05148, Pf05175, Pf08241, Pf08242, Pf09004, Pf12847, Pf13489, Pf13532, Pf13649, Pf13659, Pf13847","91801","ENSG00000137760.14","ALKBH8","11","","tRNA modification in the nucleus and cytosol","",3,0,0.936,-0.1,0.612889483907325,0.993646308931659,89.5,101.8,108.8,"",12.49,5.61,78.8,"","",84.5,95.3,102.1,76.9,102.7,96.2,89.6,95.5,4,"","",67.4,72.1,81.1,55.7,74,96.2,73,76.2,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P13861","cAMP-dependent protein kinase type II-alpha regulatory subunit OS=Homo sapiens OX=9606 GN=PRKAR2A PE=1 SV=2",0,98.517,48,17,32,17,404,45.5,5.07,100.88,17,"coagulation;metabolic process;regulation of biological process;response to stimulus","cytoplasm;cytosol;membrane","catalytic activity;enzyme regulator activity;nucleotide binding;protein binding","Pf00027, Pf02197","5576","ENSG00000114302.15","PRKAR2A","3","Insulin signaling pathway","DARPP-32 events; ROBO receptors bind AKAP5; Glucagon-like Peptide-1 (GLP1) regulates insulin secretion; Hedgehog 'off' state; Vasopressin regulates renal water homeostasis via Aquaporins; Factors involved in megakaryocyte development and platelet production; Signaling by GPCR; PKA activation in glucagon signalling; PKA activation","miRs in Muscle Cell Differentiation; Myometrial Relaxation and Contraction Pathways; G Protein Signaling Pathways; TGF-beta Signaling Pathway; Calcium Regulation in the Cardiac Cell; Sudden Infant Death Syndrome (SIDS) Susceptibility Pathways",37,0,1.034,0.05,0.617664117046555,0.99400330585989,105.8,98.7,95.5,"",0.99,1.44,3833.6,"","",3579.2,3639.7,3572,3560.4,3467.5,3379.7,3496.8,3451.6,194.5,"","",2856.2,2754.9,2836.5,2578.6,2497.4,3379.7,2849.9,2754.3,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q49A88","Coiled-coil domain-containing protein 14 OS=Homo sapiens OX=9606 GN=CCDC14 PE=1 SV=3",0,33.323,12,10,10,10,953,106.2,8.4,28.17,10,"","cytoplasm;cytoskeleton","protein binding","Pf15254","64770","","CCDC14","3","","","",0,0,0.959,-0.06,0.618195634932103,0.99400330585989,68.9,113.2,118,"",5.08,2.72,210.9,"","",342.1,351.2,327.3,369.5,363.6,379.5,359.1,357.9,10.7,"","",273,265.8,259.9,267.6,261.9,379.5,292.7,285.6,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q9Y2I1","Nischarin OS=Homo sapiens OX=9606 GN=NISCH PE=1 SV=3",0,10.59,2,3,3,3,1504,166.5,5.14,9.71,3,"cell death;cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus;transport","cytoplasm;cytosol;endosome;membrane","protein binding","Pf00787, Pf12799, Pf13855, Pf14580","11188","ENSG00000010322.15","NISCH","3","","","",0,0,0.948,-0.08,0.621140130457915,0.99400330585989,116.7,89.2,94.1,"",5.1,6.47,317.3,"","",236.6,227.4,254.9,249,238,253.9,278.4,258.2,16.1,"","",188.8,172.1,202.4,180.3,171.4,253.9,226.9,206,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q9BQS8","FYVE and coiled-coil domain-containing protein 1 OS=Homo sapiens OX=9606 GN=FYCO1 PE=1 SV=3",0,109.923,20,31,35,31,1478,166.9,4.92,104.95,31,"cellular component movement;metabolic process;regulation of biological process;transport","endosome;Golgi;membrane;vacuole","metal ion binding;nucleotide binding;protein binding","Pf01363, Pf02759, Pf03961, Pf13897","79443","ENSG00000163820.14","FYCO1","3","","","",0,0,1.048,0.07,0.630394878761917,0.994586700540924,102.6,101,96.4,"",2.31,4.62,1980.8,"","",1991.7,1950.2,1947.4,1882.8,1741.3,1832.3,1887.3,1941.4,100.5,"","",1589.4,1476.1,1546.4,1363.6,1254.1,1832.3,1538.2,1549.2,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q9P2I0","Cleavage and polyadenylation specificity factor subunit 2 OS=Homo sapiens OX=9606 GN=CPSF2 PE=1 SV=2",0,68.511,25,19,22,19,782,88.4,5.11,63.94,19,"metabolic process;transport","membrane;nucleus","protein binding;RNA binding","Pf00753, Pf07521, Pf10996, Pf12706, Pf13299","53981","ENSG00000165934.12","CPSF2","14","mRNA surveillance pathway","mRNA 3'-end processing; Transport of Mature mRNA Derived from an Intronless Transcript; mRNA Splicing - Major Pathway; Cleavage of Growing Transcript in the Termination Region ; Processing of Intronless Pre-mRNAs","mRNA Processing",16,0,0.975,-0.04,0.626147650395224,0.994586700540924,152.4,72.8,74.7,87.88,2.56,4.29,2172,9301.3,"",2132.6,2162.9,2209.2,2078,2281.6,2280.6,2107.6,2129.4,110.2,2.6,"",1701.8,1637.1,1754.3,1505,1643.3,2280.6,1717.7,1699.2,"High","High","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","O95478","Ribosome biogenesis protein NSA2 homolog OS=Homo sapiens OX=9606 GN=NSA2 PE=1 SV=1",0,36.72,34,8,10,8,260,30,10.27,30.09,8,"metabolic process","nucleus","RNA binding","Pf01201","10412","ENSG00000164346.9","NSA2","5","","","",0,0,1.04,0.06,0.62390360607607,0.994586700540924,93.9,105.1,101,"",7.77,9.89,1137.3,"","",1236.7,1309.8,1229.1,1448,1445.7,1262.5,1174.2,1185.9,57.7,"","",986.9,991.4,976,1048.7,1041.2,1262.5,957,946.3,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","O75506","Heat shock factor-binding protein 1 OS=Homo sapiens OX=9606 GN=HSBP1 PE=1 SV=1",0,17.371,57,3,6,3,76,8.5,4.36,12.64,3,"cell differentiation;regulation of biological process","cytoskeleton;nucleus","protein binding","Pf06825","3281","ENSG00000230989.6","HSBP1","16","","Attenuation phase; HSF1 activation","",6,0,1.034,0.05,0.632177427366422,0.994586700540924,97.9,102.7,99.4,"",13.32,4.31,764.7,"","",844.2,804.9,800,616.1,738.5,794,812.3,758.5,38.8,"","",673.7,609.2,635.3,446.2,531.9,794,662,605.3,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","A2VDJ0","Transmembrane protein 131-like OS=Homo sapiens OX=9606 GN=TMEM131L PE=1 SV=2",0,10.032,2,2,2,2,1609,179.2,6.86,6.06,2,"regulation of biological process;response to stimulus","cytoplasm;endoplasmic reticulum;membrane","","Pf12371","23240","ENSG00000121210.15","KIAA0922; TMEM131L","4","","","",0,0,1.051,0.07,0.632430372827036,0.994586700540924,"",153.7,146.3,"",5.47,8.46,"","","",49.1,48.8,47.7,43.5,48.2,45.8,39.4,46,"","","",39.2,36.9,37.9,31.5,34.7,45.8,32.1,36.7,"Not Found","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q13137","Calcium-binding and coiled-coil domain-containing protein 2 OS=Homo sapiens OX=9606 GN=CALCOCO2 PE=1 SV=1",0,18.253,8,3,3,3,446,52.2,5.02,11.14,3,"cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus","cytoplasm;cytoskeleton;cytosol;Golgi;membrane;nucleus;vacuole","catalytic activity;motor activity;protein binding;structural molecule activity","Pf00038, Pf01576, Pf02463, Pf04111, Pf04156, Pf06160, Pf07888, Pf09728, Pf10174, Pf11559, Pf13779, Pf14662, Pf15066, Pf15070","10241","ENSG00000136436.14","CALCOCO2","17","","","",0,0,1.041,0.06,0.635039329125707,0.995043819910131,90,107.1,102.9,"",3.77,3.59,130.1,"","",157.3,146.3,159.3,152.4,154.1,146,151.7,142.4,6.6,"","",125.5,110.7,126.5,110.4,111,146,123.6,113.6,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P15260","Interferon gamma receptor 1 OS=Homo sapiens OX=9606 GN=IFNGR1 PE=1 SV=1",0,7.561,6,3,3,3,489,54.4,4.91,4.86,3,"defense response;regulation of biological process;response to stimulus","endoplasmic reticulum;membrane","protein binding;receptor activity;signal transducer activity","Pf01108, Pf07140, Pf09294","3459","ENSG00000027697.13","IFNGR1","6","Osteoclast differentiation; Influenza A; Chagas disease (American trypanosomiasis); Salmonella infection; Tuberculosis; Cytokine-cytokine receptor interaction; Inflammatory bowel disease (IBD); Herpes simplex infection; Jak-STAT signaling pathway; Natural killer cell mediated cytotoxicity; HIF-1 signaling pathway; Th1 and Th2 cell differentiation; Measles; Toxoplasmosis; Leishmaniasis","Regulation of IFNG signaling","Type II interferon signaling (IFNG)",21,0,0.955,-0.07,0.637514336293831,0.995850856426898,87.2,104,108.8,"",7.25,4.2,260.2,"","",287.3,315.9,304.6,341.3,322.5,330.7,300.6,326.8,13.2,"","",229.3,239.1,241.9,247.2,232.3,330.7,245,260.8,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q96GA3","Protein LTV1 homolog OS=Homo sapiens OX=9606 GN=LTV1 PE=1 SV=1",0,52.431,23,10,11,10,475,54.8,4.91,36.4,10,"metabolic process;transport","cytosol;membrane;nucleus","protein binding","Pf04180","84946","ENSG00000135521.8","LTV1","6","","Major pathway of rRNA processing in the nucleolus and cytosol","",4,0,0.975,-0.04,0.640583616327898,0.997226795496399,89.9,103.7,106.4,"",6.21,3.3,955.9,"","",1113.5,1070.3,1091.4,1227.1,1115.9,1073.9,1156.7,1146,48.5,"","",888.6,810.1,866.7,888.7,803.7,1073.9,942.7,914.5,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q96EU7","C1GALT1-specific chaperone 1 OS=Homo sapiens OX=9606 GN=C1GALT1C1 PE=1 SV=1",0,18.12,12,4,4,4,318,36.4,6.84,9.51,4,"cell organization and biogenesis;metabolic process","membrane","catalytic activity;protein binding","","29071","ENSG00000171155.7","C1GALT1C1","X","Mucin type O-glycan biosynthesis; Metabolic pathways","O-linked glycosylation of mucins; Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)","",10,0,1.034,0.05,0.643053339924174,0.99822528616699,87.8,107.9,104.3,"",4.41,4.54,678,"","",817,899.2,823.6,843.2,782.8,850.1,773.7,829.9,34.4,"","",652,680.6,654,610.7,563.8,850.1,630.6,662.2,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q7Z6Z7-2","Isoform 2 of E3 ubiquitin-protein ligase HUWE1 OS=Homo sapiens OX=9606 GN=HUWE1",0,654.901,27,111,190,1,4358,479.9,5.24,588.64,111,"cell differentiation;cell organization and biogenesis;metabolic process;response to stimulus;transport","cytoplasm;cytosol;extracellular;membrane;nucleus;organelle lumen","catalytic activity;DNA binding;protein binding;RNA binding","Pf00632, Pf02825, Pf06012, Pf06025, Pf14377","10075","","HUWE1","X","","","",0,111,1.008,0.01,0.891643948933972,0.999610319815025,123.7,88.5,87.8,43.99,1.59,1.06,21243.3,40424.8,"",21185.9,21416.2,20774.4,20717.7,20820.2,20414.2,20906.7,20799.1,1077.8,11.3,"",16906.4,16209.9,16496.9,15004.6,14995.3,20414.2,17039.2,16597.2,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P09651","Heterogeneous nuclear ribonucleoprotein A1 OS=Homo sapiens OX=9606 GN=HNRNPA1 PE=1 SV=5",0,355.768,76,33,159,1,372,38.7,9.13,530.28,33,"cell communication;metabolic process;regulation of biological process;response to stimulus;transport","cytoplasm;membrane;nucleus;spliceosomal complex","DNA binding;protein binding;RNA binding","Pf00076, Pf13893, Pf14259","3178","ENSG00000135486.17","HNRNPA1","12","Spliceosome","mRNA Splicing - Major Pathway; FGFR2 alternative splicing","mRNA Processing",11,39,0.991,-0.01,0.89066921931181,0.999610319815025,101.9,98.6,99.5,84.28,10.36,2.63,12559.1,8228.1,39475,12313.2,11685.2,12008,14571.4,12013.8,12061.8,12683.1,12472.2,637.2,2.3,5,9826,8844.5,9535.5,10553.2,8652.7,12061.8,10336.9,9952.5,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q15075","Early endosome antigen 1 OS=Homo sapiens OX=9606 GN=EEA1 PE=1 SV=2",0,293.278,42,59,78,59,1411,162.4,5.68,260.98,59,"cell organization and biogenesis;metabolic process;transport","cytoplasm;cytosol;endosome;membrane","catalytic activity;metal ion binding;motor activity;protein binding;transporter activity","Pf01363, Pf01496, Pf01576, Pf04156, Pf05478, Pf09726, Pf10498, Pf12128, Pf13166","8411","ENSG00000102189.16","EEA1","12","Phagosome; Endocytosis; Tuberculosis","Toll Like Receptor 9 (TLR9) Cascade","VEGFA-VEGFR2 Signaling Pathway",8,0,1.016,0.02,0.79464171821663,0.999610319815025,118.9,91.3,89.8,29.04,2.04,2.53,11451.4,"",17369,10844.3,10809.9,11246,10761.2,10351.3,10523.7,10952.1,10794.7,581,"",2.2,8653.8,8182,8930.4,7793.7,7455.3,10523.7,8926.1,8613.9,"High","Not Found","High","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P31948","Stress-induced-phosphoprotein 1 OS=Homo sapiens OX=9606 GN=STIP1 PE=1 SV=1",0,256.497,69,44,132,44,543,62.6,6.8,386.85,44,"response to stimulus","cytoplasm;cytosol;Golgi;nucleus","protein binding;RNA binding","Pf00515, Pf12895, Pf13414, Pf13424, Pf13432","10963","ENSG00000168439.16","STIP1","11","Prion diseases","HSP90 chaperone cycle for steroid hormone receptors (SHR)","",4,0,1.014,0.02,0.819175401381315,0.999610319815025,78,111.7,110.2,48.75,1.06,2.91,19820.2,9659,"",20115.9,19868.1,19760.1,19619.7,19831.9,19258.5,19851.6,18659.2,1005.6,2.7,"",16052.6,15038.2,15691.4,14209.4,14283.5,19258.5,16179.3,14889.6,"High","High","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q8IWZ3-6","Isoform 6 of Ankyrin repeat and KH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ANKHD1",0,242.323,21,44,59,29,2617,277,5.86,199.02,44,"defense response;response to stimulus","cytoplasm","protein binding;RNA binding","Pf00013, Pf00023, Pf12796, Pf13014, Pf13606, Pf13637, Pf13857","404734; 54882","ENSG00000254996.5","ANKHD1-EIF4EBP3; ANKHD1","5","","","",0,13,0.974,-0.04,0.702174029865069,0.999610319815025,141.4,78.2,80.4,81.26,1.39,2.92,4736.3,17529.3,"",5053,5152.7,5029.1,4987.6,5234.7,5120.5,5301.3,4957,240.3,4.9,"",4032.3,3900.1,3993.6,3612.2,3770.2,5120.5,4320.6,3955.6,"High","High","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q15366-3","Isoform 3 of Poly(rC)-binding protein 2 OS=Homo sapiens OX=9606 GN=PCBP2",0,216.775,57,16,119,1,362,38.2,6.79,430.79,16,"defense response;metabolic process;regulation of biological process;response to stimulus","cytoplasm;cytosol;membrane;nucleus","DNA binding;protein binding;RNA binding","Pf00013, Pf13014","5094","ENSG00000197111.15","PCBP2","12","","","mRNA Processing",1,11,0.99,-0.01,0.916833584118373,0.999610319815025,96.1,101.4,102.4,"",3.53,2.13,3969.6,"","",4265.1,4200.3,4175.2,3930.9,4161.2,4161.1,4332.1,4298.9,201.4,"","",3403.6,3179.2,3315.5,2846.9,2997,4161.1,3530.7,3430.4,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P14314","Glucosidase 2 subunit beta OS=Homo sapiens OX=9606 GN=PRKCSH PE=1 SV=2",0,203.576,42,25,108,25,528,59.4,4.41,292.77,25,"metabolic process;regulation of biological process;response to stimulus","endoplasmic reticulum;organelle lumen","metal ion binding;protein binding","Pf07915, Pf12999, Pf13015","5589","ENSG00000130175.9","PRKCSH","19","Protein processing in endoplasmic reticulum","Advanced glycosylation endproduct receptor signaling; Post-translational protein phosphorylation; Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs); Calnexin/calreticulin cycle","",11,0,1.024,0.03,0.700868848546156,0.999610319815025,118.1,92,89.9,35.01,2.01,2.84,8650.7,11805.5,17369,9138.9,8966.6,9251.3,9404.2,9012.8,8996.4,8490.7,8970.1,438.9,3.3,2.2,7292.9,6786.8,7346.4,6810.9,6491.3,8996.4,6920,7157.9,"High","High","High","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q16555","Dihydropyrimidinase-related protein 2 OS=Homo sapiens OX=9606 GN=DPYSL2 PE=1 SV=1",0,191.223,50,25,52,25,572,62.3,6.38,162.51,25,"cell differentiation;cell organization and biogenesis;cellular component movement;development;metabolic process;regulation of biological process;response to stimulus;transport","cytoplasm;cytoskeleton;cytosol;membrane","catalytic activity;protein binding","Pf01979, Pf07969, Pf13147, Pf13594","1808","ENSG00000092964.17","DPYSL2","8","Axon guidance","Recycling pathway of L1; CRMPs in Sema3A signaling","Regulation of Microtubule Cytoskeleton; Brain-Derived Neurotrophic Factor (BDNF) signaling pathway",9,0,1.017,0.02,0.799582471734069,0.999610319815025,95.4,103.2,101.4,"",8.66,6.18,4600.3,"","",4949,5003.2,4644.7,5685.7,5375.8,4891.9,4645.2,4893.3,233.4,"","",3949.3,3786.9,3688.3,4117.8,3871.8,4891.9,3785.9,3904.7,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q9NWH9","SAFB-like transcription modulator OS=Homo sapiens OX=9606 GN=SLTM PE=1 SV=2",0,179.413,27,27,50,27,1034,117.1,7.87,172.66,27,"cell death;metabolic process;regulation of biological process","nucleus","DNA binding;RNA binding","Pf00076, Pf02037, Pf13893, Pf14259","79811","ENSG00000137776.16","SLTM","15","","","",0,0,0.976,-0.03,0.700749850817036,0.999610319815025,126.1,85.9,88,42.68,1.26,3.77,5948.4,11090,"",5537.3,5448.4,5619.6,5529.2,5412.3,5626,5711.1,5928.4,301.8,3.1,"",4418.8,4123.9,4462.5,4004.5,3898.1,5626,4654.6,4730.7,"High","High","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q9BUQ8","Probable ATP-dependent RNA helicase DDX23 OS=Homo sapiens OX=9606 GN=DDX23 PE=1 SV=3",0,171.19,47,39,53,39,820,95.5,9.55,135.62,39,"cell organization and biogenesis;metabolic process","cytoplasm;nucleus;spliceosomal complex","catalytic activity;DNA binding;nucleotide binding;protein binding;RNA binding","Pf00270, Pf00271, Pf04851","9416","ENSG00000174243.9","DDX23","12","Spliceosome","mRNA Splicing - Major Pathway; mRNA Splicing - Minor Pathway","",6,0,1.002,0,0.971916927188816,0.999610319815025,147,76.6,76.4,78.03,2.61,3.76,7525.2,"",26053.5,7308.1,7145.3,7271.9,7597.3,7710.6,7414.6,7124.3,7139.9,381.8,"",3.3,5831.9,5408.3,5774.6,5502.3,5553.4,7414.6,5806.4,5697.5,"High","Not Found","High","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q9BZF9","Uveal autoantigen with coiled-coil domains and ankyrin repeats OS=Homo sapiens OX=9606 GN=UACA PE=1 SV=2",0,162.872,28,37,41,37,1416,162.4,7.03,124.08,37,"metabolic process;regulation of biological process;response to stimulus","cytoplasm;cytoskeleton;cytosol;extracellular;nucleus","protein binding","Pf00023, Pf04111, Pf07888, Pf09726, Pf10174, Pf12128, Pf12796, Pf13606, Pf13637, Pf13857","55075","ENSG00000137831.14","UACA","15","","","",0,0,0.992,-0.01,0.890791553446782,0.999610319815025,99.7,99.8,100.6,"",4.71,4.45,5447.8,"","",5311.4,5488.4,5418.6,5906.5,5472,5523.1,5369.1,5933.8,276.4,"","",4238.5,4154.2,4302.9,4277.7,3941.1,5523.1,4375.9,4735,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P08621","U1 small nuclear ribonucleoprotein 70 kDa OS=Homo sapiens OX=9606 GN=SNRNP70 PE=1 SV=2",0,157.724,47,21,68,21,437,51.5,9.94,217.17,21,"metabolic process;regulation of biological process;response to stimulus","cytoplasm;nucleus;spliceosomal complex","protein binding;RNA binding","Pf00076, Pf12220, Pf13893, Pf14259","6625","ENSG00000104852.14","SNRNP70","19","Spliceosome","mRNA Splicing - Major Pathway","mRNA Processing",6,0,0.979,-0.03,0.733687365173621,0.999610319815025,102.4,97.7,99.8,"",3.73,3.76,8163.8,"","",7825.1,7755.2,8261.2,7570,7659,7740.9,8248.2,8176.9,414.2,"","",6244.5,5869.9,6560.2,5482.5,5516.2,7740.9,6722.4,6525,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P31947","14-3-3 protein sigma OS=Homo sapiens OX=9606 GN=SFN PE=1 SV=1",0,148.918,62,19,95,14,248,27.8,4.74,277.3,19,"cell differentiation;cell organization and biogenesis;regulation of biological process;response to stimulus","cytoplasm;cytosol;extracellular;membrane;mitochondrion;nucleus","enzyme regulator activity;protein binding","Pf00244","2810","ENSG00000175793.11","SFN","1","p53 signaling pathway; Cell cycle; Aldosterone-regulated sodium reabsorption","Translocation of GLUT4 to the plasma membrane; Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex; TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest; TP53 Regulates Metabolic Genes; Activation of BAD and translocation to mitochondria ; RHO GTPases activate PKNs","miRNA Regulation of DNA Damage Response; Myometrial Relaxation and Contraction Pathways; Calcium Regulation in the Cardiac Cell; DNA Damage Response",31,0,1.002,0,0.947313598490581,0.999610319815025,140.8,79.7,79.5,81.57,2.84,1.14,5595.6,9301.3,26843,5074.4,5371.9,5164,5365.8,5240.1,5292.3,5265.8,5154.2,283.9,2.6,3.4,4049.4,4066,4100.7,3886.1,3774.1,5292.3,4291.7,4112.9,"High","High","High","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P55795","Heterogeneous nuclear ribonucleoprotein H2 OS=Homo sapiens OX=9606 GN=HNRNPH2 PE=1 SV=1",0,143.026,40,17,64,11,449,49.2,6.3,216.29,17,"metabolic process","cytosol;membrane;nucleus","protein binding;RNA binding","Pf00076, Pf08080, Pf14259","3188","ENSG00000126945.8","HNRNPH2","X","","mRNA Splicing - Major Pathway","mRNA Processing",5,0,0.991,-0.01,0.873888457194506,0.999610319815025,90.8,104.1,105.1,"",21.21,9.12,1026.9,"","",1161.1,1195.8,1138.1,1715.6,1378,1169.7,1122.6,1208.6,52.1,"","",926.6,905.1,903.8,1242.5,992.5,1169.7,914.9,964.4,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P23396","40S ribosomal protein S3 OS=Homo sapiens OX=9606 GN=RPS3 PE=1 SV=2",0,139.646,82,23,104,23,243,26.7,9.66,300.17,23,"cell death;cell division;cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus;transport","cytoplasm;cytoskeleton;cytosol;endoplasmic reticulum;membrane;mitochondrion;nucleus;organelle lumen;ribosome","catalytic activity;DNA binding;protein binding;RNA binding;structural molecule activity","Pf00189, Pf07650","6188","ENSG00000149273.14","RPS3","11","Ribosome","Peptide chain elongation; Eukaryotic Translation Termination; Viral mRNA Translation; Formation of the ternary complex, and subsequently, the 43S complex; L13a-mediated translational silencing of Ceruloplasmin expression; Selenocysteine synthesis; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); GTP hydrolysis and joining of the 60S ribosomal subunit; Ribosomal scanning and start codon recognition; Major pathway of rRNA processing in the nucleolus and cytosol; Regulation of expression of SLITs and ROBOs; Translation initiation complex formation; Formation of a pool of free 40S subunits; SRP-dependent cotranslational protein targeting to membrane","Cytoplasmic Ribosomal Proteins",38,0,1.016,0.02,0.788487514651718,0.999610319815025,86.1,107.8,106.1,27.49,0.91,1.97,12728.6,8585.8,"",13108.8,13072.3,12856.6,13093,13143.2,12976.7,12769,12559.4,645.8,2.4,"",10460.9,9894.4,10209.4,9482.5,9466.1,12976.7,10406.9,10022.1,"High","High","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q7Z478","ATP-dependent RNA helicase DHX29 OS=Homo sapiens OX=9606 GN=DHX29 PE=1 SV=2",0,133.719,24,27,34,27,1369,155.1,8.09,94.41,27,"metabolic process","cytoplasm;mitochondrion","catalytic activity;nucleotide binding;protein binding;RNA binding","Pf00270, Pf00271, Pf04408, Pf07717","54505","ENSG00000067248.9","DHX29","5","","","",0,0,1.025,0.04,0.742775754466094,0.999610319815025,141.9,80,78,78.43,5.58,5.79,2972.2,10374.5,"",3168,3092,3191.3,2818.5,3256.7,3074.7,3031.7,2826.9,150.8,2.9,"",2528.1,2340.3,2534.2,2041.3,2345.6,3074.7,2470.9,2255.8,"High","High","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q96EN8","Molybdenum cofactor sulfurase OS=Homo sapiens OX=9606 GN=MOCOS PE=1 SV=2",0,129.855,38,25,35,25,888,98.1,6.7,118.34,25,"metabolic process","cytosol","catalytic activity;metal ion binding;protein binding","Pf00266, Pf03473, Pf03476","55034","ENSG00000075643.5","MOCOS","18","","Molybdenum cofactor biosynthesis","",4,0,1.032,0.05,0.710919539323791,0.999610319815025,156.9,72.6,70.4,89.89,6.6,1.73,2948.6,13236.4,"",2942.7,2842,3096.4,2642.8,2731.9,2825.6,2779.8,2838.6,149.6,3.7,"",2348.3,2151.1,2458.8,1914,1967.6,2825.6,2265.6,2265.1,"High","High","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q641Q2","WASH complex subunit 2A OS=Homo sapiens OX=9606 GN=WASHC2A PE=1 SV=3",0,125.063,20,22,26,5,1341,147.1,4.81,94.15,22,"transport","cytosol;endosome;membrane","","Pf15255","387680","ENSG00000099290.15","FAM21A; WASHC2A","10","Endocytosis","","",1,0,0.978,-0.03,0.80907662774137,0.999610319815025,86.3,105.7,108,"",2.84,5.41,352.8,"","",439.6,442.3,424.3,416.9,446.5,436.6,448.6,398.3,17.9,"","",350.8,334.8,336.9,301.9,321.6,436.6,365.6,317.8,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","A2RRP1","Neuroblastoma-amplified sequence OS=Homo sapiens OX=9606 GN=NBAS PE=1 SV=2",0,121.381,13,31,32,31,2371,268.4,5.96,100.45,31,"metabolic process;regulation of biological process;transport","cytoplasm;cytosol;endoplasmic reticulum;membrane","protein binding","Pf08314, Pf15492","51594","ENSG00000151779.12","NBAS","2","","COPI-dependent Golgi-to-ER retrograde traffic","",5,0,1.019,0.03,0.761931352951993,0.999610319815025,101.7,100.1,98.2,"",4.22,4.42,4014.9,"","",3915,3992.6,4128.8,3730.1,3932.9,3902.8,3856.5,3566.4,203.7,"","",3124.2,3022,3278.7,2701.5,2832.6,3902.8,3143.1,2845.9,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","O60884","DnaJ homolog subfamily A member 2 OS=Homo sapiens OX=9606 GN=DNAJA2 PE=1 SV=1",0,116.983,41,20,35,20,412,45.7,6.48,107.11,20,"metabolic process;regulation of biological process;response to stimulus","cytosol;membrane","enzyme regulator activity;metal ion binding;nucleotide binding;protein binding","Pf00226, Pf00684, Pf01556","10294","ENSG00000069345.11","DNAJA2","16","Protein processing in endoplasmic reticulum","HSP90 chaperone cycle for steroid hormone receptors (SHR)","",4,0,0.977,-0.03,0.763739516655886,0.999610319815025,125.6,86.2,88.2,43.89,3.21,3.52,4330.3,8228.1,"",4027.3,4192.5,4161.2,3908.1,4212.3,4165.8,4277.6,3941,219.7,2.3,"",3213.8,3173.3,3304.4,2830.4,3033.8,4165.8,3486.3,3144.8,"High","High","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q99729-3","Isoform 3 of Heterogeneous nuclear ribonucleoprotein A/B OS=Homo sapiens OX=9606 GN=HNRNPAB",0,112.553,42,14,34,13,285,30.6,7.91,121.32,14,"cell organization and biogenesis;regulation of biological process","cytoplasm;nucleus","DNA binding;protein binding;RNA binding","Pf00076, Pf08143, Pf13893, Pf14259","3182","ENSG00000197451.11","HNRNPAB","5","","","Preimplantation Embryo; mRNA Processing",2,0,0.995,-0.01,0.963622797898881,0.999610319815025,105.2,97.2,97.7,"",10.71,2.2,4996.4,"","",4334.8,4475.2,4761.3,5480.8,4747.8,4500.1,4649.9,4629.6,253.5,"","",3459.2,3387.3,3780.9,3969.4,3419.5,4500.1,3789.7,3694.3,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q92538","Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 OS=Homo sapiens OX=9606 GN=GBF1 PE=1 SV=2",0,110.169,15,25,29,25,1859,206.3,5.73,79.98,25,"cell organization and biogenesis;cellular component movement;metabolic process;regulation of biological process;response to stimulus;transport","cytoplasm;cytosol;Golgi;membrane;mitochondrion;organelle lumen","protein binding","Pf01369, Pf12783","8729","ENSG00000107862.4","GBF1","10","Endocytosis","Clathrin derived vesicle budding; COPI-dependent Golgi-to-ER retrograde traffic; VxPx cargo-targeting to cilium; COPI-mediated anterograde transport","",18,0,1.025,0.04,0.781822202628438,0.999610319815025,146.1,77.9,76,81.67,5.36,3.13,2970.3,11090,"",3170.4,3271.5,2957.2,2931.6,3105.5,3039.3,2936,2902,150.7,3.1,"",2530,2476.2,2348.3,2123.2,2236.7,3039.3,2392.9,2315.7,"High","High","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q8IWV7","E3 ubiquitin-protein ligase UBR1 OS=Homo sapiens OX=9606 GN=UBR1 PE=1 SV=1",0,106.152,14,19,26,19,1749,200.1,6.01,92.29,19,"metabolic process;regulation of biological process;response to stimulus","cytoplasm;cytosol;proteasome","catalytic activity;metal ion binding;protein binding","Pf02207, Pf02617","197131","ENSG00000159459.11","UBR1","15","","Antigen processing: Ubiquitination & Proteasome degradation","",4,0,0.989,-0.02,0.751726547711045,0.999610319815025,105.1,96.9,98,"",5.1,1.66,2079.4,"","",1922.7,1853.1,1913.6,2084.8,1961.5,1888,1948.8,1932.1,105.5,"","",1534.3,1402.6,1519.6,1509.9,1412.7,1888,1588.3,1541.8,"High","High","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","O00148","ATP-dependent RNA helicase DDX39A OS=Homo sapiens OX=9606 GN=DDX39A PE=1 SV=2",0,102.891,41,17,50,7,427,49.1,5.68,145.07,17,"metabolic process;regulation of biological process;response to stimulus;transport","cytoplasm;membrane;nucleus;spliceosomal complex","catalytic activity;nucleotide binding;protein binding;RNA binding","Pf00270, Pf00271, Pf14617","10212","ENSG00000123136.14","DDX39A","19","","Cleavage of Growing Transcript in the Termination Region ; Transport of Mature mRNA derived from an Intron-Containing Transcript; mRNA 3'-end processing","",9,12,0.99,-0.02,0.867187614715397,0.999610319815025,106.9,96,97,11.95,1.88,0.93,8455.5,10016.8,"",8424.4,8187.5,8344,8078.2,8395,8250.2,8309.9,8417.9,429,2.8,"",6722.7,6197.1,6625.9,5850.6,6046.3,8250.2,6772.7,6717.3,"High","High","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q9Y2W2","WW domain-binding protein 11 OS=Homo sapiens OX=9606 GN=WBP11 PE=1 SV=1",0,100.3,28,22,40,22,641,70,8.38,112.15,22,"metabolic process;regulation of biological process","cytoplasm;cytosol;nucleus;spliceosomal complex","DNA binding;enzyme regulator activity;protein binding;RNA binding","Pf09429","51729","ENSG00000084463.7","WBP11","12","Spliceosome","mRNA Splicing - Major Pathway","",5,0,0.982,-0.03,0.769220078461097,0.999610319815025,104.2,97,98.8,"",1.47,1.61,6431.3,"","",6136.2,5990.6,5931.3,5981.3,6093.9,6110.4,5905.4,6093.3,326.3,"","",4896.7,4534.3,4710,4331.9,4389,6110.4,4813,4862.3,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q9NUQ9","Protein FAM49B OS=Homo sapiens OX=9606 GN=FAM49B PE=1 SV=1",0,100.269,54,14,32,14,324,36.7,6.06,101.35,14,"regulation of biological process;transport","extracellular;membrane;organelle lumen","protein binding","Pf07159","51571","ENSG00000153310.19","FAM49B","8","","Platelet degranulation","",4,0,1.022,0.03,0.73722746988895,0.999610319815025,100.7,100.7,98.6,"",6.92,4.14,4044.5,"","",4237.8,4092.9,3996.2,3594.9,3728.5,3976.3,3939.9,4123.9,205.2,"","",3381.8,3097.9,3173.4,2603.6,2685.4,3976.3,3211.1,3290.8,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q13045","Protein flightless-1 homolog OS=Homo sapiens OX=9606 GN=FLII PE=1 SV=2",0,98.416,24,26,35,1,1269,144.7,6.05,96.66,26,"cell organization and biogenesis;development;metabolic process;regulation of biological process","cytoplasm;cytoskeleton;cytosol;nucleus","protein binding","Pf00626, Pf12799, Pf13855","2314","ENSG00000177731.15; ENSG00000284571.1","FLII","17; CHR_HSCHR17_3_CTG1","","","",0,0,0.96,-0.06,0.770896199982196,0.999610319815025,111.8,92.2,96,"",25.01,17.34,256.2,"","",210,212.3,262.7,137.7,180.1,226.4,273.6,213.5,13,"","",167.6,160.7,208.6,99.7,129.7,226.4,223,170.4,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","O15446","DNA-directed RNA polymerase I subunit RPA34 OS=Homo sapiens OX=9606 GN=CD3EAP PE=1 SV=1",0,95.966,48,12,25,12,510,55,8.51,97.97,12,"metabolic process;regulation of biological process;response to stimulus","chromosome;cytosol;mitochondrion;nucleus","catalytic activity;RNA binding","Pf08208","10849","ENSG00000117877.10","CD3EAP","19","","RNA Polymerase I Chain Elongation; NoRC negatively regulates rRNA expression; RNA Polymerase I Transcription Termination; RNA Polymerase I Promoter Escape; B-WICH complex positively regulates rRNA expression; RNA Polymerase I Transcription Initiation","",12,0,1.038,0.05,0.695971676064588,0.999610319815025,88.1,107.9,104,"",3.97,4.18,950,"","",1240.3,1137.8,1181.1,1145.5,1047.4,1120.3,1158.5,1121.6,48.2,"","",989.8,861.2,937.9,829.6,754.4,1120.3,944.2,895,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q86W56","Poly(ADP-ribose) glycohydrolase OS=Homo sapiens OX=9606 GN=PARG PE=1 SV=1",0,93.664,25,21,25,21,976,111,6.43,81.39,21,"metabolic process;response to stimulus","cytoplasm;cytosol;membrane;mitochondrion;nucleus;organelle lumen","catalytic activity;protein binding","Pf05028","8505; 670","ENSG00000227345.8","PARG; BPHL","10; 6","","POLB-Dependent Long Patch Base Excision Repair","",5,0,0.997,0,0.879426117528078,0.999610319815025,171.8,64,64.2,105.78,3.21,1.84,2733.8,18960.3,"",2723.2,2643,2751.7,2561.3,2623.1,2660,2720.8,2725.1,138.7,5.3,"",2173.1,2000.5,2185.1,1855,1889.2,2660,2217.5,2174.6,"High","High","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","O14920","Inhibitor of nuclear factor kappa-B kinase subunit beta OS=Homo sapiens OX=9606 GN=IKBKB PE=1 SV=1",0,91.642,27,18,21,18,756,86.5,5.78,68.97,18,"cell organization and biogenesis;defense response;metabolic process;regulation of biological process;response to stimulus","cytoplasm;cytosol;membrane;nucleus","catalytic activity;nucleotide binding;protein binding","Pf00069, Pf00240, Pf07714, Pf12179","3551","ENSG00000104365.13","IKBKB","8","MicroRNAs in cancer; mTOR signaling pathway; Chemokine signaling pathway; Osteoclast differentiation; NF-kappa B signaling pathway; Th1 and Th2 cell differentiation; MAPK signaling pathway; Antifolate resistance; Small cell lung cancer; Insulin resistance; Pancreatic cancer; Apoptosis; RIG-I-like receptor signaling pathway; TNF signaling pathway; Pathways in cancer; B cell receptor signaling pathway; Hepatitis C; Shigellosis; Hepatitis B; HTLV-I infection; Epstein-Barr virus infection; Toll-like receptor signaling pathway; Adipocytokine signaling pathway; NOD-like receptor signaling pathway; Prostate cancer; Chronic myeloid leukemia; Non-alcoholic fatty liver disease (NAFLD); Influenza A; T cell receptor signaling pathway; Type II diabetes mellitus; FoxO signaling pathway; Cytosolic DNA-sensing pathway; Epithelial cell signaling in Helicobacter pylori infection; Chagas disease (American trypanosomiasis); Acute myeloid leukemia; Ras signaling pathway; Insulin signaling pathway; Toxoplasmosis; Neurotrophin signaling pathway; Herpes simplex infection; PI3K-Akt signaling pathway","IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation; IKBKG deficiency causes anhidrotic ectodermal dysplasia with immunodeficiency (EDA-ID) (via TLR); Downstream TCR signaling; NOD1/2 Signaling Pathway; NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10; TRAF6 mediated NF-kB activation; TICAM1, RIP1-mediated IKK complex recruitment ; TAK1 activates NFkB by phosphorylation and activation of IKKs complex; MAP3K8 (TPL2)-dependent MAPK1/3 activation; TNFR1-induced NFkappaB signaling pathway; RIP-mediated NFkB activation via ZBP1; Activated TLR4 signalling; Interleukin-1 family signaling; IRAK1 recruits IKK complex; p75NTR recruits signalling complexes; IKBKB deficiency causes SCID; IKK complex recruitment mediated by RIP1; ER-Phagosome pathway; FCERI mediated NF-kB activation; Activation of NF-kappaB in B cells; NF-kB is activated and signals survival; Regulation of TNFR1 signaling; Signalling by NGF; IkBA variant leads to EDA-ID; CLEC7A (Dectin-1) signaling","Nucleotide-binding Oligomerization Domain (NOD) pathway; Osteopontin Signaling; Regulation of toll-like receptor signaling pathway; MicroRNAs in cardiomyocyte hypertrophy; Type II diabetes mellitus; IL-1 signaling pathway; RANKL/RANK (Receptor activator of NFKB (ligand)) Signaling Pathway; Leptin signaling pathway; TNF related weak inducer of apoptosis (TWEAK) Signaling Pathway; IL17 signaling pathway; B Cell Receptor Signaling Pathway; TNF alpha Signaling Pathway; AGE/RAGE pathway; Interleukin-11 Signaling Pathway; Brain-Derived Neurotrophic Factor (BDNF) signaling pathway; Quercetin and Nf-kB/ AP-1 Induced Cell Apoptosis; Apoptosis; EBV LMP1 signaling; Structural Pathway of Interleukin 1 (IL-1); Cardiac Hypertrophic Response; NLR Proteins; Rac1/Pak1/p38/MMP-2 pathway; Photodynamic therapy-induced NF-kB survival signaling; MAPK Signaling Pathway; MAPK  and NFkB Signalling Pathways Inhibited by Yersinia YopJ; Toll-like Receptor Signaling; T-Cell antigen Receptor (TCR) pathway during Staphylococcus aureus infection; RIG-I-like Receptor Signaling; Chemokine signaling pathway; Focal Adhesion-PI3K-Akt-mTOR-signaling pathway; IL-4 Signaling Pathway; Insulin Signaling; T-Cell antigen Receptor (TCR)  Signaling Pathway; Estrogen signaling pathway; Toll-like receptor signaling pathway",144,0,0.991,-0.01,0.812190858690925,0.999610319815025,197.7,51,51.4,120.08,6.58,2.45,2306.1,28261.6,"",2010.5,2120.1,2042.6,2321.5,2116.8,2081.2,2028.6,2148.1,117,7.9,"",1604.4,1604.7,1622,1681.3,1524.6,2081.2,1653.3,1714.1,"High","High","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P05114","Non-histone chromosomal protein HMG-14 OS=Homo sapiens OX=9606 GN=HMGN1 PE=1 SV=3",0,90.107,47,7,26,7,100,10.7,9.6,100.46,7,"cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus","chromosome;cytoplasm;nucleus","DNA binding;protein binding","","3150","ENSG00000205581.10","HMGN1","21","Herpes simplex infection","Dual incision in TC-NER; Formation of TC-NER Pre-Incision Complex; Gap-filling DNA repair synthesis and ligation in TC-NER","ATM Signaling Network in Development and Disease; p38 MAPK Signaling Pathway",9,0,0.981,-0.03,0.674498414150553,0.999610319815025,97.9,100.1,102,"",5.38,9.51,2051.8,"","",2069.2,2099.7,2093.3,2316.6,1983.7,2096.5,2180.2,2469.4,104.1,"","",1651.2,1589.3,1662.3,1677.8,1428.7,2096.5,1776.9,1970.5,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q9UI10","Translation initiation factor eIF-2B subunit delta OS=Homo sapiens OX=9606 GN=EIF2B4 PE=1 SV=2",0,88.405,31,14,19,1,523,57.5,9.38,68.73,14,"metabolic process;regulation of biological process;response to stimulus","cytoplasm;cytosol","protein binding;RNA binding","Pf01008","8890","ENSG00000115211.15","EIF2B4","2","RNA transport","Recycling of eIF2:GDP","Translation Factors",7,0,1.024,0.03,0.768902310579774,0.999610319815025,106.6,97.9,95.5,"",14.2,2.83,207,"","",204,193.7,186.4,145,185.2,185.8,195.9,185,10.5,"","",162.8,146.6,148,105,133.4,185.8,159.7,147.6,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q15637-5","Isoform 5 of Splicing factor 1 OS=Homo sapiens OX=9606 GN=SF1",0,86.611,22,14,39,2,673,71.7,9.58,117.77,14,"cell differentiation;cell organization and biogenesis;metabolic process;regulation of biological process","nucleus;ribosome;spliceosomal complex","metal ion binding;protein binding;RNA binding","Pf00013, Pf00098, Pf13014","7536","ENSG00000168066.20","SF1","11","","","",0,17,0.997,0,0.988006821699899,0.999610319815025,101.6,99.1,99.3,"",3.09,2.98,4949.1,"","",4856.7,4793.1,4652.2,5011.7,4876.8,4801.2,4582.4,4892.1,251.1,"","",3875.7,3627.9,3694.3,3629.7,3512.4,4801.2,3734.7,3903.8,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","O43896","Kinesin-like protein KIF1C OS=Homo sapiens OX=9606 GN=KIF1C PE=1 SV=3",0,85.364,20,21,25,15,1103,122.9,6.9,72.5,21,"cellular component movement;transport","cytoplasm;cytoskeleton;endoplasmic reticulum;Golgi","catalytic activity;motor activity;nucleotide binding;protein binding;RNA binding","Pf00225, Pf00498","10749","ENSG00000129250.11","KIF1C","17","","COPI-dependent Golgi-to-ER retrograde traffic; Kinesins","",8,0,0.985,-0.02,0.799226135376151,0.999610319815025,92.7,102.9,104.4,"",3.26,4.22,914.5,"","",1016.4,1013.7,1078.1,1004.9,988.4,1023.2,1093.4,1037.9,46.4,"","",811.1,767.3,856.1,727.8,711.9,1023.2,891.1,828.2,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P08069","Insulin-like growth factor 1 receptor OS=Homo sapiens OX=9606 GN=IGF1R PE=1 SV=1",0,83.776,18,23,26,20,1367,154.7,5.8,81.05,23,"cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus","membrane","catalytic activity;nucleotide binding;protein binding;receptor activity;signal transducer activity","Pf00041, Pf00069, Pf00757, Pf01030, Pf01826, Pf07714, Pf14843","3480","ENSG00000140443.13","IGF1R","15","Rap1 signaling pathway; Ras signaling pathway; Endocytosis; mTOR signaling pathway; EGFR tyrosine kinase inhibitor resistance; Breast cancer; Signaling pathways regulating pluripotency of stem cells; Ovarian steroidogenesis; Long-term depression; Proteoglycans in cancer; Glioma; Longevity regulating pathway - multiple species; Transcriptional misregulation in cancer; Pathways in cancer; Longevity regulating pathway; AMPK signaling pathway; Progesterone-mediated oocyte maturation; Endocrine resistance; Focal adhesion; FoxO signaling pathway; Oocyte meiosis; Melanoma; HIF-1 signaling pathway; Adherens junction; Prostate cancer; PI3K-Akt signaling pathway","IRS-related events triggered by IGF1R; SHC-related events triggered by IGF1R","MicroRNAs in cardiomyocyte hypertrophy; Human Thyroid Stimulating Hormone (TSH) signaling pathway; Signaling Pathways in Glioblastoma; Apoptosis; Focal Adhesion; Factors and pathways affecting insulin-like growth factor (IGF1)-Akt signaling; Focal Adhesion-PI3K-Akt-mTOR-signaling pathway; Endochondral Ossification; Insulin Signaling; Senescence and Autophagy in Cancer",42,2,0.987,-0.02,0.749957706015043,0.999610319815025,92.4,103.1,104.5,"",3.25,1.91,1902,"","",2037.8,2166.6,2079.2,2180.4,2135.2,2165.3,2123.9,2216,96.5,"","",1626.2,1639.9,1651.1,1579.1,1537.8,2165.3,1731,1768.3,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q15437","Protein transport protein Sec23B OS=Homo sapiens OX=9606 GN=SEC23B PE=1 SV=2",0,82.42,29,15,20,14,767,86.4,6.89,69.49,15,"transport","cytoplasm;cytosol;endoplasmic reticulum;membrane","metal ion binding;protein binding","Pf00626, Pf04810, Pf04811, Pf04815, Pf08033","10483","ENSG00000101310.14","SEC23B","20","Protein processing in endoplasmic reticulum","","Sterol Regulatory Element-Binding Proteins (SREBP) signalling",2,0,1.01,0.02,0.987836600603609,0.999610319815025,172.1,64.3,63.6,101.4,2.46,2.74,2063.6,12520.9,"",1891.3,1903.6,1818.2,1925.2,1876.4,1879.2,1970.9,1853.3,104.7,3.5,"",1509.3,1440.8,1443.8,1394.3,1351.4,1879.2,1606.3,1478.9,"High","High","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q8IYB8","ATP-dependent RNA helicase SUPV3L1, mitochondrial OS=Homo sapiens OX=9606 GN=SUPV3L1 PE=1 SV=1",0,80.693,22,15,21,15,786,87.9,7.99,66.35,15,"cell organization and biogenesis;metabolic process;regulation of biological process","mitochondrion;nucleus;organelle lumen","catalytic activity;DNA binding;nucleotide binding;protein binding;RNA binding","Pf00271, Pf12513","6832","ENSG00000156502.13","SUPV3L1","10","","","",0,0,1.042,0.06,0.655207780858661,0.999610319815025,151.5,75.8,72.7,90.34,2.43,3,2286.3,10374.5,"",2436.1,2436.5,2474,2336.5,2376.5,2440.9,2301.4,2289.5,116,2.9,"",1944,1844.2,1964.6,1692.2,1711.6,2440.9,1875.7,1827,"High","High","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q86VS8","Protein Hook homolog 3 OS=Homo sapiens OX=9606 GN=HOOK3 PE=1 SV=2",0,79.129,28,20,24,19,718,83.1,5.17,71.04,20,"cell organization and biogenesis;regulation of biological process;transport","cytoplasm;cytoskeleton;cytosol;Golgi","catalytic activity;motor activity;protein binding;transporter activity","Pf01496, Pf01576, Pf02463, Pf04156, Pf05622, Pf05667, Pf08317, Pf09787, Pf12128, Pf13166","84376","ENSG00000168172.8","HOOK3","8","","","",0,1,1,0,0.928126731966922,0.999610319815025,99.7,100.2,100.1,"",5.83,2.74,1665.5,"","",1683.5,1638.1,1665,1858.2,1735.1,1628.4,1656.8,1690.2,84.5,"","",1343.4,1239.9,1322.2,1345.8,1249.7,1628.4,1350.3,1348.7,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q02878","60S ribosomal protein L6 OS=Homo sapiens OX=9606 GN=RPL6 PE=1 SV=3",0,77.994,31,13,68,13,288,32.7,10.58,179.96,13,"cell organization and biogenesis;metabolic process;regulation of biological process;transport","cytosol;membrane;nucleus;ribosome","DNA binding;protein binding;RNA binding;structural molecule activity","Pf01159, Pf03868","6128","ENSG00000089009.15","RPL6","12","Ribosome","Peptide chain elongation; Eukaryotic Translation Termination; Viral mRNA Translation; L13a-mediated translational silencing of Ceruloplasmin expression; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); Selenocysteine synthesis; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; Regulation of expression of SLITs and ROBOs; Formation of a pool of free 40S subunits; SRP-dependent cotranslational protein targeting to membrane","Cytoplasmic Ribosomal Proteins",34,0,0.976,-0.03,0.695033701941727,0.999610319815025,99.3,99.2,101.6,"",2.06,2.29,9920,"","",10292.9,9950.7,9870.6,9852,10150.3,10157.2,10211.6,9715.1,503.3,"","",8213.8,7531.7,7838.2,7135.2,7310.5,10157.2,8322.6,7752.4,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","O00186","Syntaxin-binding protein 3 OS=Homo sapiens OX=9606 GN=STXBP3 PE=1 SV=2",0,76.484,27,16,25,16,592,67.7,7.8,80.16,16,"cell organization and biogenesis;regulation of biological process;response to stimulus;transport","cytoplasm;cytosol;membrane","protein binding","Pf00995","6814","ENSG00000116266.10","STXBP3","1","","Translocation of GLUT4 to the plasma membrane; Disinhibition of SNARE formation","Insulin Signaling",8,0,1.001,0,0.92917240582713,0.999610319815025,103.6,98.3,98.2,"",1.56,2.18,3035.3,"","",2854.1,2814.5,2907.2,2905.7,2846.7,2883,2870.5,2989.2,154,"","",2277.6,2130.3,2308.6,2104.4,2050.3,2883,2339.5,2385.3,"High","Not Found","High","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","O95292","Vesicle-associated membrane protein-associated protein B/C OS=Homo sapiens OX=9606 GN=VAPB PE=1 SV=3",0,74.325,56,14,22,13,243,27.2,7.3,67.25,14,"cell organization and biogenesis;cellular homeostasis;metabolic process;regulation of biological process;response to stimulus;transport","cytoplasm;endoplasmic reticulum;Golgi;membrane","protein binding","Pf00635, Pf00843","9217","ENSG00000124164.15","VAPB","20","","Sphingolipid de novo biosynthesis","",4,1,1.021,0.03,0.742965466074873,0.999610319815025,101.8,100.2,98.1,"",1.29,3.32,4133.2,"","",4001.4,4122.6,4047.5,4088.8,3967.5,4055.7,3755.9,3998.9,209.7,"","",3193.1,3120.4,3214.1,2961.3,2857.5,4055.7,3061.1,3191,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q5JWF2","Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas OS=Homo sapiens OX=9606 GN=GNAS PE=1 SV=2",0,73.506,14,14,25,1,1037,111,5.03,78.66,14,"metabolic process;regulation of biological process;response to stimulus","cytosol;membrane","catalytic activity;metal ion binding;nucleotide binding;protein binding;signal transducer activity","Pf00025, Pf00503, Pf08477","2778","ENSG00000087460.24","GNAS","20","","G alpha (z) signalling events; Prostacyclin signalling through prostacyclin receptor; PKA activation in glucagon signalling; G alpha (s) signalling events; Glucagon-type ligand receptors; G alpha (i) signalling events; Glucagon-like Peptide-1 (GLP1) regulates insulin secretion; Hedgehog 'off' state; Vasopressin regulates renal water homeostasis via Aquaporins","Human Thyroid Stimulating Hormone (TSH) signaling pathway; Endothelin Pathways; Corticotropin-releasing hormone signaling pathway; Common Pathways Underlying Drug Addiction; Myometrial Relaxation and Contraction Pathways; G Protein Signaling Pathways; Calcium Regulation in the Cardiac Cell; Estrogen signaling pathway; Serotonin Receptor 4/6/7 and NR3C Signaling",32,0,0.968,-0.05,0.828353952666768,0.999610319815025,82.9,106.8,110.3,"",4.79,4.34,177.4,"","",226.9,229.8,239.4,213.1,250.9,227.5,231.8,240.2,9,"","",181.1,173.9,190.1,154.3,180.7,227.5,188.9,191.7,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q8TEU7","Rap guanine nucleotide exchange factor 6 OS=Homo sapiens OX=9606 GN=RAPGEF6 PE=1 SV=2",0,72.241,14,16,16,14,1601,179.3,6.4,50.52,16,"cell organization and biogenesis;regulation of biological process;response to stimulus","cytoplasm;cytosol;membrane","protein binding","Pf00027, Pf00595, Pf00617, Pf00618, Pf00788, Pf13180","51735","ENSG00000158987.20","RAPGEF6","5","Rap1 signaling pathway","","",1,2,1.017,0.02,0.829364474877204,0.999610319815025,95.9,102.9,101.2,"",3.62,1.91,1399.4,"","",1436,1522.1,1562.4,1481.4,1490.2,1483.8,1427.7,1469.2,71,"","",1145.9,1152.1,1240.7,1072.9,1073.3,1483.8,1163.6,1172.4,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q9NUL7","Probable ATP-dependent RNA helicase DDX28 OS=Homo sapiens OX=9606 GN=DDX28 PE=1 SV=2",0,70.418,29,17,18,17,540,59.5,10.42,47.24,17,"cell organization and biogenesis;metabolic process","cytosol;mitochondrion;nucleus;organelle lumen","catalytic activity;nucleotide binding;RNA binding","Pf00270, Pf00271","55794","ENSG00000182810.6","DDX28","16","","","",0,0,1.029,0.04,0.760224949465699,0.999610319815025,99.9,101.5,98.6,"",3.09,2.5,2542.6,"","",2604.2,2561.4,2731.8,2560.5,2433,2500.4,2517.8,2585.9,129,"","",2078.2,1938.7,2169.3,1854.4,1752.3,2500.4,2052,2063.5,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q9P219","Protein Daple OS=Homo sapiens OX=9606 GN=CCDC88C PE=1 SV=3",0,69.598,10,16,17,16,2028,228.1,6.23,52.02,16,"cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus;transport","cytoplasm;cytoskeleton","catalytic activity;motor activity;protein binding","Pf01576, Pf02463, Pf03962, Pf04111, Pf04156, Pf05483, Pf05557, Pf05622, Pf06160, Pf09726, Pf09728, Pf12128, Pf13514, Pf14915","440193","ENSG00000015133.18","CCDC88C","14","","Negative regulation of TCF-dependent signaling by DVL-interacting proteins","Ectoderm Differentiation",5,0,1.005,0.01,0.957495540458378,0.999610319815025,114.9,92.8,92.3,"",3.56,3.58,1314.6,"","",1036.2,1065.9,1056.4,1124.9,1042,1045.1,1067.6,1124.7,66.7,"","",826.9,806.8,838.9,814.7,750.5,1045.1,870.1,897.5,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q96FC9-2","Isoform 2 of ATP-dependent DNA helicase DDX11 OS=Homo sapiens OX=9606 GN=DDX11",0,68.166,21,17,19,5,906,101.6,7.85,66.27,17,"cell organization and biogenesis;development;metabolic process;regulation of biological process;response to stimulus","cytoplasm;nucleus","catalytic activity;DNA binding;metal ion binding;nucleotide binding;protein binding;RNA binding","Pf06733, Pf13307","1663","ENSG00000013573.16","DDX11","12","","","",0,8,0.998,0,0.957716648770656,0.999610319815025,96.2,101.8,102,"",0.54,1.03,963.8,"","",1022.8,1018.1,1028.8,1016.7,1023.4,1003.7,1021.8,1027.5,48.9,"","",816.2,770.6,817,736.3,737.1,1003.7,832.8,819.9,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q13033","Striatin-3 OS=Homo sapiens OX=9606 GN=STRN3 PE=1 SV=3",0,67.151,19,14,19,11,797,87.2,5.36,60.03,14,"regulation of biological process;response to stimulus","cytoplasm;Golgi;membrane;nucleus","protein binding","Pf00400, Pf08232","29966","ENSG00000196792.11","STRN3","14","","","",0,0,0.992,-0.01,0.856676233406087,0.999610319815025,96.4,101.4,102.2,"",3.9,2.6,1105.7,"","",1158.3,1166.2,1213,1102.5,1159.6,1195.6,1183.7,1126.9,56.1,"","",924.3,882.7,963.2,798.5,835.2,1195.6,964.7,899.2,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q9BVS4","Serine/threonine-protein kinase RIO2 OS=Homo sapiens OX=9606 GN=RIOK2 PE=1 SV=2",0,65.794,26,11,16,11,552,63.2,5.94,54.51,11,"metabolic process;regulation of biological process","cytoplasm;cytosol;membrane","catalytic activity;metal ion binding;nucleotide binding","Pf01163, Pf01636, Pf06293, Pf09202","55781","ENSG00000058729.10","RIOK2","5","Ribosome biogenesis in eukaryotes","Major pathway of rRNA processing in the nucleolus and cytosol","",5,0,1.033,0.05,0.746625634004535,0.999610319815025,103.6,99.8,96.6,"",3.11,5.65,1844.8,"","",1787.7,1733.3,1768.9,1864.8,1884.7,1653.2,1726.1,1715.6,93.6,"","",1426.6,1311.9,1404.7,1350.6,1357.4,1653.2,1406.8,1369,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q8NDV7","Trinucleotide repeat-containing gene 6A protein OS=Homo sapiens OX=9606 GN=TNRC6A PE=1 SV=2",0,64.659,14,16,17,16,1962,210.2,7.01,57.98,16,"regulation of biological process;response to stimulus","cytoplasm;cytosol;Golgi","protein binding;RNA binding","Pf10427, Pf13893, Pf14259","27327","ENSG00000090905.18","TNRC6A","16","","Post-transcriptional silencing by small RNAs; RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function; Ca2+ pathway; Competing endogenous RNAs (ceRNAs) regulate PTEN translation; Transcriptional regulation by small RNAs; Regulation of RUNX1 Expression and Activity; MAPK6/MAPK4 signaling; TP53 Regulates Metabolic Genes; Oncogene Induced Senescence; Pre-NOTCH Transcription and Translation; Oxidative Stress Induced Senescence","",30,0,1.024,0.03,0.72392663864283,0.999610319815025,97.9,102.2,99.8,"",7.02,5.42,567.6,"","",620.2,603.2,581.9,526.2,576.2,580.8,622.9,546.4,28.8,"","",494.9,456.6,462.1,381.1,415,580.8,507.7,436,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q16512","Serine/threonine-protein kinase N1 OS=Homo sapiens OX=9606 GN=PKN1 PE=1 SV=2",0,63.311,25,19,22,17,942,103.9,6.37,61.82,19,"cell death;cell organization and biogenesis;cellular component movement;metabolic process;regulation of biological process;response to stimulus","cytoplasm;cytosol;endosome;membrane;nucleus","catalytic activity;nucleotide binding;protein binding","Pf00069, Pf00433, Pf02185, Pf07714, Pf14531, Pf15456","5585","ENSG00000123143.12","PKN1","19","PI3K-Akt signaling pathway; Salmonella infection","Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3","Apoptosis-related network due to altered Notch3 in ovarian cancer; G13 Signaling Pathway",9,0,0.974,-0.04,0.670793946183166,0.999610319815025,101.3,98,100.6,"",1.95,1.95,1438.8,"","",1394.5,1388.4,1373.1,1437,1443.7,1401.7,1414.3,1463.1,73,"","",1112.8,1050.9,1090.4,1040.7,1039.8,1401.7,1152.7,1167.5,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q7L5N1","COP9 signalosome complex subunit 6 OS=Homo sapiens OX=9606 GN=COPS6 PE=1 SV=1",0,62.596,47,12,18,12,327,36.1,5.73,54.5,12,"cell organization and biogenesis;metabolic process;response to stimulus","cytoplasm;cytosol;nucleus","protein binding","Pf01398, Pf13012","10980","ENSG00000168090.9","COPS6","7","","Cargo recognition for clathrin-mediated endocytosis; DNA Damage Recognition in GG-NER; Formation of TC-NER Pre-Incision Complex; Neddylation","Nucleotide-binding Oligomerization Domain (NOD) pathway",14,0,1.025,0.04,0.856827770389537,0.999610319815025,168.6,66.5,64.9,96.43,6.02,6.68,2233.1,11805.5,"",1969.2,2085.6,2086.8,1834.2,1955.9,2054.4,1999,1756.7,113.3,3.3,"",1571.4,1578.6,1657.1,1328.4,1408.7,2054.4,1629.2,1401.8,"High","High","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q9Y679","Ancient ubiquitous protein 1 OS=Homo sapiens OX=9606 GN=AUP1 PE=1 SV=2",0,61.645,31,13,21,13,410,45.8,8.65,65.33,13,"","","","","","","","","","","",0,0,1.039,0.06,0.713873301787616,0.999610319815025,184.6,58.8,56.6,116.89,3.41,5.64,1874.4,"",19737.5,1903.6,1990.6,1974.8,1848.7,1757.2,1893.7,2009.4,1838.9,95.1,"",2.5,1519.1,1506.7,1568.2,1338.9,1265.6,1893.7,1637.7,1467.4,"High","Not Found","High","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P63000-2","Isoform B of Ras-related C3 botulinum toxin substrate 1 OS=Homo sapiens OX=9606 GN=RAC1",0,60.279,44,10,27,9,211,23.5,8.63,78.99,10,"cell organization and biogenesis;cell proliferation;cellular component movement;coagulation;defense response;metabolic process;regulation of biological process;response to stimulus;transport","cytoplasm;cytosol;membrane","catalytic activity;nucleotide binding;protein binding","Pf00071, Pf08477","5879","ENSG00000136238.17","RAC1","7","","","Androgen receptor signaling pathway; Nucleotide-binding Oligomerization Domain (NOD) pathway; Regulation of toll-like receptor signaling pathway; Target Of Rapamycin (TOR) Signaling; Physiological and Pathological Hypertrophy  of the Heart; MicroRNAs in cardiomyocyte hypertrophy; Integrin-mediated Cell Adhesion; RANKL/RANK (Receptor activator of NFKB (ligand)) Signaling Pathway; Leptin signaling pathway; TNF related weak inducer of apoptosis (TWEAK) Signaling Pathway; Prolactin Signaling Pathway; Regulation of Microtubule Cytoskeleton; RalA downstream regulated genes; B Cell Receptor Signaling Pathway; TNF alpha Signaling Pathway; AGE/RAGE pathway; Brain-Derived Neurotrophic Factor (BDNF) signaling pathway; Spinal Cord Injury; Alpha 6 Beta 4 signaling pathway; Amyotrophic lateral sclerosis (ALS); Cardiac Hypertrophic Response; Focal Adhesion; Rac1/Pak1/p38/MMP-2 pathway; Wnt Signaling Pathway Netpath; IL-6 signaling pathway; Hepatitis C and Hepatocellular Carcinoma; TGF-beta Signaling Pathway; MAPK Signaling Pathway; VEGFA-VEGFR2 Signaling Pathway; Chemokine signaling pathway; Microglia Pathogen Phagocytosis Pathway; Robo4 and VEGF Signaling Pathways Crosstalk; p38 MAPK Signaling Pathway; Wnt Signaling Pathway; EGF/EGFR Signaling Pathway; Insulin Signaling; Regulation of Actin Cytoskeleton; G13 Signaling Pathway; Interferon type I signaling pathways; DNA Damage Response (only ATM dependent); Toll-like receptor signaling pathway",41,1,1.025,0.04,0.711786555441453,0.999610319815025,141.8,80.1,78.1,69.87,1.89,3.26,3634.5,10732.2,"",3574.4,3581.7,3449.5,3480.3,3488.6,3575.5,3392.8,3318.3,184.4,3,"",2852.4,2711,2739.2,2520.6,2512.6,3575.5,2765.2,2647.9,"High","High","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q8IXT5","RNA-binding protein 12B OS=Homo sapiens OX=9606 GN=RBM12B PE=1 SV=2",0,59.065,23,20,22,20,1001,118,6.81,51.65,20,"","","protein binding;RNA binding","Pf00076, Pf14259","389677","ENSG00000183808.11","RBM12B","8","","","",0,0,0.982,-0.03,0.706987555796299,0.999610319815025,100.4,98.9,100.7,"",5.36,0.59,2164.1,"","",2140.8,2123.1,2165.9,1922,2169.7,2171.3,2188.4,2157.5,109.8,"","",1708.4,1607,1719.9,1392,1562.7,2171.3,1783.6,1721.6,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q9Y4C1","Lysine-specific demethylase 3A OS=Homo sapiens OX=9606 GN=KDM3A PE=1 SV=4",0,57.873,13,14,15,14,1321,147.2,8.07,46.05,14,"cell differentiation;cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus","chromosome;cytoplasm;membrane;nucleus","catalytic activity;DNA binding;metal ion binding;protein binding","Pf02373","55818","ENSG00000115548.16","KDM3A","2","","HDMs demethylate histones","",3,0,0.976,-0.03,0.781343799323804,0.999610319815025,83,107.2,109.8,"",6.17,4.94,697.7,"","",930.8,805.4,900.9,900.1,883.7,909.9,935.4,991.4,35.4,"","",742.8,609.6,715.4,651.9,636.5,909.9,762.4,791.1,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q9HBM0","Vezatin OS=Homo sapiens OX=9606 GN=VEZT PE=1 SV=3",0,56.678,20,12,14,12,779,88.6,5.2,39.35,12,"","cytosol;membrane;nucleus","protein binding","Pf04290, Pf12632","55591","ENSG00000028203.17","VEZT","12","","","",0,0,0.966,-0.05,0.684946333056526,0.999610319815025,103.9,96.4,99.8,"",7.08,6.09,547.9,"","",506.3,510.6,533.2,450,537.7,564.1,515.5,488.7,27.8,"","",404,386.5,423.4,325.9,387.3,564.1,420.1,390,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q9NUI1","Peroxisomal 2,4-dienoyl-CoA reductase OS=Homo sapiens OX=9606 GN=DECR2 PE=1 SV=1",0,55.589,44,14,18,14,292,30.8,9.22,51.09,14,"metabolic process","membrane","catalytic activity;protein binding","Pf00106, Pf08659, Pf13561","26063","ENSG00000242612.6; ENSG00000274296.3","DECR2","16; CHR_HSCHR16_CTG2","Peroxisome","Beta-oxidation of very long chain fatty acids","",6,0,1.013,0.02,0.953330567510328,0.999610319815025,88.2,106.6,105.2,"",3.49,5.36,1777.8,"","",2139.2,2167.3,2156.7,2008.4,2271.1,2179.5,2061.6,2019.2,90.2,"","",1707.1,1640.4,1712.6,1454.6,1635.7,2179.5,1680.2,1611.3,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P00374","Dihydrofolate reductase OS=Homo sapiens OX=9606 GN=DHFR PE=1 SV=2",0,54.343,70,15,22,15,187,21.4,7.42,65.84,15,"cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus","cytoplasm;cytosol;mitochondrion","catalytic activity;nucleotide binding;protein binding;RNA binding;translation regulator activity","Pf00186","1719; 573971","ENSG00000228716.6","DHFR; DHFRP1","5; 18","One carbon pool by folate; Antifolate resistance; Metabolic pathways; Folate biosynthesis","Activation of E2F1 target genes at G1/S; Metabolism of folate and pterines; eNOS activation and regulation; Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation","Fluoropyrimidine Activity; Folate Metabolism; One Carbon Metabolism; Retinoblastoma (RB) in Cancer; Trans-sulfuration and one carbon metabolism; Nucleotide Metabolism",23,0,1.019,0.03,0.768634019759589,0.999610319815025,99.6,101.1,99.3,"",1.02,2.42,3541.9,"","",3582.9,3647.5,3605.2,3561.5,3633.6,3431.3,3501.5,3556,179.7,"","",2859.2,2760.8,2862.9,2579.4,2617,3431.3,2853.8,2837.6,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P61254","60S ribosomal protein L26 OS=Homo sapiens OX=9606 GN=RPL26 PE=1 SV=1",0,53.332,51,11,48,2,145,17.2,10.55,117.83,11,"cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus;transport","cytoplasm;cytosol;membrane;ribosome","protein binding;RNA binding;structural molecule activity","Pf00467","6154","ENSG00000161970.12","RPL26","17","Ribosome","Peptide chain elongation; Eukaryotic Translation Termination; Viral mRNA Translation; L13a-mediated translational silencing of Ceruloplasmin expression; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); Selenocysteine synthesis; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; Regulation of expression of SLITs and ROBOs; Formation of a pool of free 40S subunits; SRP-dependent cotranslational protein targeting to membrane","Cytoplasmic Ribosomal Proteins",34,12,0.997,0,0.955636912095568,0.999610319815025,106.9,96.4,96.7,"",4.66,2.77,6238.2,"","",5620,5621.1,5607.5,6152,5629.7,5580.9,5930.5,5649.7,316.5,"","",4484.8,4254.6,4452.9,4455.5,4054.7,5580.9,4833.4,4508.3,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P10620","Microsomal glutathione S-transferase 1 OS=Homo sapiens OX=9606 GN=MGST1 PE=1 SV=1",0,52.238,13,5,12,5,155,17.6,9.39,51.87,5,"cell differentiation;cell organization and biogenesis;metabolic process;response to stimulus;transport","endoplasmic reticulum;membrane;mitochondrion;nucleus","antioxidant activity;catalytic activity;protein binding","Pf01124","4257","ENSG00000008394.12","MGST1","12","Platinum drug resistance; Metabolism of xenobiotics by cytochrome P450; Chemical carcinogenesis; Glutathione metabolism; Drug metabolism - cytochrome P450","Glutathione conjugation; Neutrophil degranulation; Aflatoxin activation and detoxification","Aryl Hydrocarbon Receptor Pathway; Oxidative Stress; Metapathway biotransformation",16,0,0.985,-0.02,0.772940206304121,0.999610319815025,99.8,99.3,100.9,"",3.62,6.35,1454.6,"","",1471.8,1527.7,1425,1410.6,1555.9,1482.2,1459.5,1333.5,73.8,"","",1174.5,1156.3,1131.6,1021.6,1120.6,1482.2,1189.5,1064.1,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","O43488","Aflatoxin B1 aldehyde reductase member 2 OS=Homo sapiens OX=9606 GN=AKR7A2 PE=1 SV=3",0,51.377,35,11,19,11,359,39.6,7.17,45.92,11,"metabolic process","cytoplasm;cytosol;Golgi","catalytic activity;protein binding","Pf00248","8574","ENSG00000053371.12","AKR7A2","1","Metabolism of xenobiotics by cytochrome P450","Aflatoxin activation and detoxification","Aflatoxin B1 metabolism; Metapathway biotransformation",6,0,1.011,0.02,0.933717520452055,0.999610319815025,94.5,103.3,102.2,"",1.63,1.98,961.8,"","",1036.3,1036.6,1066.2,1066.2,1037.9,1023.6,1041.3,1072.7,48.8,"","",827,784.6,846.7,772.2,747.5,1023.6,848.7,856,"High","High","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","O00257","E3 SUMO-protein ligase CBX4 OS=Homo sapiens OX=9606 GN=CBX4 PE=1 SV=3",0,50.719,24,13,13,13,560,61.3,9.36,37.6,13,"cell organization and biogenesis;metabolic process;regulation of biological process","nucleus","catalytic activity;DNA binding;protein binding;RNA binding","Pf00385","8535","ENSG00000141582.14","CBX4","17","","RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known; SUMOylation of chromatin organization proteins; Regulation of PTEN gene transcription; SUMOylation of DNA damage response and repair proteins; Oxidative Stress Induced Senescence; SUMOylation of RNA binding proteins","",21,0,0.987,-0.02,0.903401042664177,0.999610319815025,101.7,98.5,99.8,"",4.68,4.23,944.1,"","",914.5,913.3,982.4,879.3,917.1,935.6,988.8,896.8,47.9,"","",729.8,691.3,780.1,636.8,660.5,935.6,805.9,715.6,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q8N8A2","Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit B OS=Homo sapiens OX=9606 GN=ANKRD44 PE=1 SV=3",0,50.207,11,10,11,8,993,107.5,6.3,34.06,10,"","","protein binding","Pf00023, Pf12796, Pf13606, Pf13637, Pf13857","91526","ENSG00000065413.18","ANKRD44","2","","","",0,0,0.96,-0.06,0.653837634177549,0.999610319815025,204.3,46.9,48.8,134.62,4.23,5.91,281.9,11447.7,"",403.5,418.2,406.8,442.5,427.8,407.9,431.2,469.3,14.3,3.2,"",322,316.5,323,320.5,308.1,407.9,351.4,374.5,"High","High","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q9Y237-2","Isoform 2 of Peptidyl-prolyl cis-trans isomerase NIMA-interacting 4 OS=Homo sapiens OX=9606 GN=PIN4",0,48.81,54,8,17,8,156,16.6,9.96,49.06,8,"metabolic process","nucleus;organelle lumen","catalytic activity;DNA binding;protein binding;RNA binding","Pf00639, Pf13145, Pf13616","5303","ENSG00000102309.12","PIN4","X","","","",0,0,1.003,0,0.967504531368542,0.999610319815025,103.5,98.4,98.1,"",5.31,3.37,1635.9,"","",1591.3,1519.1,1492.3,1678.4,1552.3,1490.8,1618.6,1546.8,83,"","",1269.9,1149.8,1185,1215.6,1118,1490.8,1319.2,1234.3,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q96N67","Dedicator of cytokinesis protein 7 OS=Homo sapiens OX=9606 GN=DOCK7 PE=1 SV=4",0,48.269,9,18,18,17,2140,242.4,6.8,48.36,18,"cell differentiation;cell organization and biogenesis;development;regulation of biological process;response to stimulus","","protein binding","Pf06920, Pf11878, Pf14429","85440","ENSG00000116641.17","DOCK7","1","","MET activates RAP1 and RAC1; Factors involved in megakaryocyte development and platelet production","",7,1,0.991,-0.01,0.932037148673723,0.999610319815025,97.6,100.8,101.7,"",3.28,3.71,839.6,"","",860.1,843.2,910.5,874,861.8,843.7,888.3,918.4,42.6,"","",686.4,638.2,723,633,620.7,843.7,724,732.9,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q53HC9","EARP and GARP complex-interacting protein 1 OS=Homo sapiens OX=9606 GN=EIPR1 PE=1 SV=2",0,47.749,25,8,10,8,387,43.6,5.06,27.94,8,"","","protein binding","Pf00400","7260","ENSG00000032389.12","TSSC1; EIPR1","2","","","",0,0,0.991,-0.01,0.848334802144214,0.999610319815025,182.5,58.5,59,115.87,5.11,4.21,1492,15025.1,"",1533.8,1499.7,1583.2,1401.2,1447.5,1493.1,1568.9,1583.1,75.7,4.2,"",1224,1135.1,1257.2,1014.8,1042.5,1493.1,1278.7,1263.3,"High","High","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","O14867","Transcription regulator protein BACH1 OS=Homo sapiens OX=9606 GN=BACH1 PE=1 SV=2",0,47.645,14,8,11,8,736,81.9,5.05,40.41,8,"metabolic process;regulation of biological process;response to stimulus","cytoplasm;cytosol;nucleus","catalytic activity;DNA binding;protein binding","Pf00170, Pf00651, Pf03131, Pf07716","571","ENSG00000156273.15","BACH1","21","","","Integrated Cancer pathway",1,0,0.956,-0.07,0.682976438541841,0.999610319815025,70.6,112.1,117.3,"",5.18,8.15,149.8,"","",232.3,240.3,235.5,260.3,253.8,229.5,244,278.2,7.6,"","",185.4,181.9,187,188.5,182.8,229.5,198.9,222,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P18084","Integrin beta-5 OS=Homo sapiens OX=9606 GN=ITGB5 PE=1 SV=1",0,46.19,17,12,13,12,799,88,6.06,39.72,12,"cell differentiation;cell organization and biogenesis;regulation of biological process;response to stimulus","cell surface;membrane","protein binding;receptor activity","Pf00362, Pf07965, Pf08725","3693","ENSG00000082781.11","ITGB5","3","PI3K-Akt signaling pathway; Proteoglycans in cancer; Dilated cardiomyopathy; ECM-receptor interaction; Focal adhesion; Arrhythmogenic right ventricular cardiomyopathy (ARVC); Hypertrophic cardiomyopathy (HCM); Regulation of actin cytoskeleton; Phagosome","ECM proteoglycans; Integrin cell surface interactions; Cross-presentation of particulate exogenous antigens (phagosomes); Smooth Muscle Contraction; Molecules associated with elastic fibres; Syndecan interactions","Integrin-mediated Cell Adhesion; Arrhythmogenic Right Ventricular Cardiomyopathy; miRNA targets in ECM and membrane receptors; Focal Adhesion; VEGFA-VEGFR2 Signaling Pathway; Focal Adhesion-PI3K-Akt-mTOR-signaling pathway",29,0,1.022,0.03,0.800652362869583,0.999610319815025,98.3,102,99.7,"",7.5,3.35,382.4,"","",384.7,409.4,437.1,368.4,363.2,390.1,388.1,388.2,19.4,"","",307,309.9,347.1,266.8,261.6,390.1,316.3,309.8,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P62714","Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform OS=Homo sapiens OX=9606 GN=PPP2CB PE=1 SV=1",0,45.534,38,9,10,2,309,35.6,5.43,33.37,9,"cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus","chromosome;cytoplasm;cytoskeleton;cytosol;nucleus","catalytic activity;metal ion binding;protein binding","Pf00149","5516","ENSG00000104695.12","PPP2CB","8","Hippo signaling pathway; Chagas disease (American trypanosomiasis); Hepatitis C; mRNA surveillance pathway; Adrenergic signaling in cardiomyocytes; TGF-beta signaling pathway; Sphingolipid signaling pathway; Long-term depression; PI3K-Akt signaling pathway; Oocyte meiosis; AMPK signaling pathway; Tight junction; Dopaminergic synapse","Glycolysis; AXIN missense mutants destabilize the destruction complex; PP2A-mediated dephosphorylation of key metabolic factors; APC truncation mutants have impaired AXIN binding; CTLA4 inhibitory signaling; Activated TLR4 signalling; Separation of Sister Chromatids; MASTL Facilitates Mitotic Progression; S37 mutants of beta-catenin aren't phosphorylated; S33 mutants of beta-catenin aren't phosphorylated; S45 mutants of beta-catenin aren't phosphorylated; Misspliced GSK3beta mutants stabilize beta-catenin; Cyclin A/B1/B2 associated events during G2/M transition; T41 mutants of beta-catenin aren't phosphorylated; RAF activation; ERKs are inactivated; Beta-catenin phosphorylation cascade; Negative regulation of MAPK pathway; Platelet sensitization by LDL; Signaling by GPCR; Interleukin-20 family signaling; Spry regulation of FGF signaling; DARPP-32 events; PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling; Regulation of TP53 Degradation; Disassembly of the destruction complex and recruitment of AXIN to the membrane; Cyclin D associated events in G1; Inhibition of replication initiation of damaged DNA by RB1/E2F1; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; Truncations of AMER1 destabilize the destruction complex","Serotonin Transporter Activity; Dopamine metabolism; Focal Adhesion-PI3K-Akt-mTOR-signaling pathway; Wnt Signaling Pathway and Pluripotency; Exercise-induced Circadian Regulation; Glycogen Metabolism; Monoamine Transport",139,8,0.997,0,0.929440213400188,0.999610319815025,99,100.4,100.6,"",4.12,3.18,1363.9,"","",1344.4,1364,1474.9,1401.3,1397.2,1364.8,1464.3,1375.9,69.2,"","",1072.8,1032.4,1171.2,1014.9,1006.3,1364.8,1193.4,1097.9,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P50542","Peroxisomal targeting signal 1 receptor OS=Homo sapiens OX=9606 GN=PEX5 PE=1 SV=3",0,45.487,16,7,8,7,639,70.8,4.54,27.32,7,"cell organization and biogenesis;metabolic process;regulation of biological process;transport","cytoplasm;cytosol;Golgi;membrane;organelle lumen","protein binding","Pf00515, Pf13414, Pf13424, Pf13432","5830","ENSG00000139197.10","PEX5","12","Peroxisome","E3 ubiquitin ligases ubiquitinate target proteins","",5,0,1.042,0.06,0.663628316850623,0.999610319815025,95.2,104.5,100.3,"",6.5,3.01,299.6,"","",329.8,353.5,327.5,301.4,310.5,314.1,332.3,316.8,15.2,"","",263.2,267.6,260.1,218.3,223.6,314.1,270.8,252.8,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","O00743","Serine/threonine-protein phosphatase 6 catalytic subunit OS=Homo sapiens OX=9606 GN=PPP6C PE=1 SV=1",0,44.587,38,9,15,9,305,35.1,5.69,47.31,9,"cell organization and biogenesis;metabolic process","cytoplasm;cytosol;membrane","catalytic activity;metal ion binding;protein binding","Pf00149","5537","ENSG00000119414.11","PPP6C","9","","COPII (Coat Protein 2) Mediated Vesicle Transport","",8,0,1.007,0.01,0.954074960025908,0.999610319815025,188.1,56.1,55.7,110.82,5.06,4.3,2343.5,19318,"",1877.2,2019.9,2124.3,1996.2,1989.1,1999.1,2074,1868.1,118.9,5.4,"",1498,1528.9,1686.9,1445.7,1432.6,1999.1,1690.3,1490.7,"High","High","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P40937","Replication factor C subunit 5 OS=Homo sapiens OX=9606 GN=RFC5 PE=1 SV=1",0,43.592,28,11,22,11,340,38.5,7.2,60.03,11,"cell organization and biogenesis;cellular homeostasis;metabolic process;regulation of biological process;response to stimulus","nucleus","catalytic activity;DNA binding;nucleotide binding;protein binding","Pf00004, Pf03215, Pf05496, Pf06068, Pf08542, Pf13086, Pf13173, Pf13177, Pf13401, Pf13479","5985","ENSG00000111445.13","RFC5","12","Nucleotide excision repair; DNA replication; Mismatch repair","Translesion Synthesis by POLH; Termination of translesion DNA synthesis; Translesion synthesis by POLI; Recognition of DNA damage by PCNA-containing replication complex; Translesion synthesis by REV1; Polymerase switching on the C-strand of the telomere; Regulation of TP53 Activity through Phosphorylation; PCNA-Dependent Long Patch Base Excision Repair; G2/M DNA damage checkpoint; Translesion synthesis by POLK; Gap-filling DNA repair synthesis and ligation in TC-NER; Presynaptic phase of homologous DNA pairing and strand exchange; Gap-filling DNA repair synthesis and ligation in GG-NER; Dual Incision in GG-NER; Polymerase switching; Activation of ATR in response to replication stress; Processing of DNA double-strand break ends; Dual incision in TC-NER; HDR through Single Strand Annealing (SSA)","Retinoblastoma (RB) in Cancer; DNA Replication",57,0,1.009,0.01,0.884373835300595,0.999610319815025,159.6,70.5,69.9,92.2,3.96,2.19,4158.8,"",19737.5,4008.6,3996.4,4169.9,3784.7,4027.1,4015.7,3845.5,3915.3,211,"",2.5,3198.9,3024.9,3311.3,2741,2900.4,4015.7,3134.1,3124.3,"High","Not Found","High","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q96S15","GATOR complex protein WDR24 OS=Homo sapiens OX=9606 GN=WDR24 PE=1 SV=2",0,42.956,13,10,10,10,790,88.2,6.52,29.95,10,"","","","","","","","","","","",0,0,1.019,0.03,0.831073741346231,0.999610319815025,93.6,104.2,102.3,"",2.83,3.23,437.6,"","",492.1,482,492,463.1,474.6,481.6,495.5,458.4,22.2,"","",392.7,364.8,390.7,335.4,341.8,481.6,403.8,365.8,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q9NQT5","Exosome complex component RRP40 OS=Homo sapiens OX=9606 GN=EXOSC3 PE=1 SV=3",0,42.005,39,8,14,8,275,29.6,8.1,40.01,8,"metabolic process;regulation of biological process","cytoplasm;cytosol;nucleus","catalytic activity;protein binding;RNA binding","","51010","ENSG00000107371.12","EXOSC3","9","RNA degradation","Major pathway of rRNA processing in the nucleolus and cytosol; mRNA decay by 3' to 5' exoribonuclease; ATF4 activates genes; Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA; Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA; KSRP (KHSRP) binds and destabilizes mRNA","",15,0,0.985,-0.02,0.726463508490792,0.999610319815025,96.3,101.1,102.6,"",3.95,2.97,2099.1,"","",2282.4,2177.6,2080.2,2232.4,2237.6,2185.8,2237.8,2345.1,106.5,"","",1821.4,1648.2,1651.9,1616.8,1611.6,2185.8,1823.8,1871.3,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P02686","Myelin basic protein OS=Homo sapiens OX=9606 GN=MBP PE=1 SV=3",0,41.364,26,7,10,7,304,33.1,9.79,35.98,7,"cell communication;cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus","membrane;nucleus","protein binding;structural molecule activity","Pf01669","4155","ENSG00000197971.14","MBP","18","","","Neural Crest Differentiation; Glial Cell Differentiation; Spinal Cord Injury; Structural Pathway of Interleukin 1 (IL-1); Mecp2 and Associated Rett Syndrome; MAPK Cascade",6,0,1.032,0.05,0.726955813364312,0.999610319815025,91.1,106.1,102.8,"",4.98,4.07,285.8,"","",350.4,329.4,335.9,310.5,321.1,344.8,314,323.6,14.5,"","",279.6,249.3,266.7,224.9,231.3,344.8,255.9,258.2,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q6IQ49","Replication stress response regulator SDE2 OS=Homo sapiens OX=9606 GN=SDE2 PE=1 SV=1",0,40.774,27,11,14,11,451,49.7,6.05,39.18,11,"","nucleus","","Pf13019, Pf13297","163859","ENSG00000143751.9","SDE2","1","","","",0,0,0.993,-0.01,0.962400341432236,0.999610319815025,99.4,99.9,100.6,"",3.11,5.09,676,"","",678.2,680.5,646.3,696.3,653.8,689,679.3,737.7,34.3,"","",541.2,515.1,513.2,504.3,470.9,689,553.6,588.7,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q96HB5","Coiled-coil domain-containing protein 120 OS=Homo sapiens OX=9606 GN=CCDC120 PE=1 SV=1",0,39.951,19,10,11,10,630,67.5,9.38,25.68,10,"cell organization and biogenesis;development","cytoplasm;endosome","protein binding","Pf11819","90060","ENSG00000147144.12","CCDC120","X","","","",0,0,0.987,-0.02,0.915457087905366,0.999610319815025,97.2,100.7,102.1,"",3.58,2.67,518.4,"","",565,543.1,531.4,519.7,539.8,565.3,549.3,531.2,26.3,"","",450.9,411.1,422,376.4,388.8,565.3,447.7,423.9,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q86UT6","NLR family member X1 OS=Homo sapiens OX=9606 GN=NLRX1 PE=1 SV=1",0,39.353,10,9,9,9,975,107.5,7.37,25.38,9,"defense response;regulation of biological process;response to stimulus","membrane;mitochondrion","nucleotide binding;protein binding","Pf05729","79671","ENSG00000160703.15","NLRX1","11","RIG-I-like receptor signaling pathway; Influenza A; NOD-like receptor signaling pathway","Negative regulators of DDX58/IFIH1 signaling","RIG-I-like Receptor Signaling",8,0,0.987,-0.02,0.903568555143329,0.999610319815025,110.6,94.1,95.3,"",7.47,6.91,350.8,"","",308.9,288,315.8,267,270.7,302.5,302,320.4,17.8,"","",246.5,218,250.8,193.4,195,302.5,246.1,255.7,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q9BVG8","Kinesin-like protein KIFC3 OS=Homo sapiens OX=9606 GN=KIFC3 PE=1 SV=4",0,38.701,10,8,9,7,833,92.7,7.69,26.31,8,"cell organization and biogenesis;cellular component movement;metabolic process;regulation of biological process","cytoplasm;cytoskeleton;Golgi;membrane","catalytic activity;motor activity;nucleotide binding;protein binding","Pf00225, Pf04111, Pf05557, Pf08317, Pf12128","3801","ENSG00000140859.15","KIFC3","16","","","Ectoderm Differentiation",1,0,0.976,-0.03,0.771589765983674,0.999610319815025,90.4,103.5,106,"",0.75,5.49,431.6,"","",496.9,490.3,491.6,497.8,503.6,540.9,473,508.8,21.9,"","",396.5,371.1,390.4,360.5,362.7,540.9,385.5,406,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q8WV44","E3 ubiquitin-protein ligase TRIM41 OS=Homo sapiens OX=9606 GN=TRIM41 PE=1 SV=3",0,37.873,15,8,8,8,630,71.6,5.06,27.77,8,"metabolic process","cytoplasm;nucleus","catalytic activity;metal ion binding;protein binding;structural molecule activity","Pf00038, Pf00097, Pf00622, Pf00643, Pf13639, Pf13765, Pf13923, Pf15227","90933","ENSG00000146063.19","TRIM41","5","","Antigen processing: Ubiquitination & Proteasome degradation","",4,0,0.972,-0.04,0.832408462003257,0.999610319815025,69.5,113.6,116.9,"",4.96,2.33,155.7,"","",245.6,264.2,268.9,244.1,261.6,272.4,258,262.5,7.9,"","",196,200,213.5,176.8,188.4,272.4,210.3,209.5,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","O00625","Pirin OS=Homo sapiens OX=9606 GN=PIR PE=1 SV=1",0,37.062,26,7,21,7,290,32.1,6.92,58.47,7,"cell differentiation;metabolic process;regulation of biological process","cytoplasm;cytosol;nucleus","catalytic activity;metal ion binding;protein binding","Pf02678, Pf05726","8544","ENSG00000087842.10","PIR","X","","Digestion","",2,0,0.993,-0.01,0.824251884369407,0.999610319815025,95.6,101.9,102.6,"",6.97,4.04,1718.7,"","",1878.2,1851.2,1811.7,1604,1849.4,1839,1927.6,1745.9,87.2,"","",1498.8,1401.2,1438.7,1161.7,1332,1839,1571,1393.2,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P99999","Cytochrome c OS=Homo sapiens OX=9606 GN=CYCS PE=1 SV=2",0,36.47,58,8,19,8,105,11.7,9.57,54.35,8,"cell death;cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus;transport","cytosol;membrane;mitochondrion;nucleus","catalytic activity;metal ion binding;protein binding","Pf00034, Pf13442, Pf14495","54205","ENSG00000172115.8","CYCS","7","Huntington's disease; Small cell lung cancer; Alzheimer's disease; Legionellosis; Toxoplasmosis; Viral myocarditis; Pathways in cancer; Herpes simplex infection; Hepatitis B; p53 signaling pathway; Apoptosis; Influenza A; Apoptosis - multiple species; Sulfur metabolism; Platinum drug resistance; Metabolic pathways; Amyotrophic lateral sclerosis (ALS); Non-alcoholic fatty liver disease (NAFLD); Parkinson's disease; Tuberculosis; Colorectal cancer","Transcriptional activation of mitochondrial biogenesis; Activation of caspases through apoptosome-mediated cleavage; TP53 Regulates Metabolic Genes; Respiratory electron transport; Release of apoptotic factors from the mitochondria; Formation of apoptosome; Detoxification of Reactive Oxygen Species","miRNA Regulation of DNA Damage Response; Alzheimers Disease; AGE/RAGE pathway; Parkinsons Disease Pathway; Nanomaterial induced apoptosis; Apoptosis; Fas Ligand (FasL) pathway and Stress induction of Heat Shock Proteins (HSP) regulation; Apoptosis Modulation by HSP70; Oxidative Damage; DNA Damage Response",54,0,1.023,0.03,0.758941986242361,0.999610319815025,103.5,99.4,97.1,"",1.53,6.62,3512.3,"","",3337.1,3447.7,3397.8,3344.2,3289.9,3609.3,3075.8,3297.8,178.2,"","",2663,2609.6,2698.2,2422,2369.5,3609.3,2506.8,2631.6,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P36542","ATP synthase subunit gamma, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1C PE=1 SV=1",0,35.808,21,6,19,6,298,33,9.22,48.96,6,"cell organization and biogenesis;metabolic process;transport","membrane;mitochondrion;organelle lumen","catalytic activity;RNA binding;transporter activity","Pf00231","509","ENSG00000165629.19","ATP5C1","10","Parkinson's disease; Oxidative phosphorylation; Metabolic pathways; Alzheimer's disease; Huntington's disease","Cristae formation; Formation of ATP by chemiosmotic coupling","Electron Transport Chain",13,0,1.01,0.01,0.880618501073997,0.999610319815025,96.2,102.4,101.4,"",1.03,1.29,3729.1,"","",4009.6,3960.2,3981.6,3912.9,3963.9,3984.9,3877.4,3902,189.2,"","",3199.7,2997.5,3161.8,2833.9,2854.9,3984.9,3160.1,3113.7,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q5R372","Rab GTPase-activating protein 1-like OS=Homo sapiens OX=9606 GN=RABGAP1L PE=1 SV=1",0,35.22,12,11,12,9,815,92.5,5.31,33.4,11,"regulation of biological process;transport","endosome;Golgi;nucleus","enzyme regulator activity;protein binding","Pf00566, Pf00640, Pf12473","9910","ENSG00000152061.23","RABGAP1L","1","","","",0,0,1.023,0.03,0.777894683027653,0.999610319815025,109.7,96.2,94.1,"",0.74,2.34,1121.5,"","",978.1,993.1,978.8,987.8,949.1,949,974,996.1,56.9,"","",780.5,751.7,777.3,715.4,683.6,949,793.8,794.9,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q86VP1","Tax1-binding protein 1 OS=Homo sapiens OX=9606 GN=TAX1BP1 PE=1 SV=2",0,34.396,16,12,13,12,789,90.8,5.43,33.9,12,"cell death;cell organization and biogenesis;cellular component movement;metabolic process;regulation of biological process","cytosol","catalytic activity;metal ion binding;motor activity;protein binding","Pf01576, Pf02463, Pf04156, Pf05483, Pf05557, Pf05622, Pf05911, Pf07888, Pf09304, Pf09726, Pf10174, Pf11559, Pf12128, Pf12718, Pf13166, Pf13851","8887","ENSG00000106052.13","TAX1BP1","7","","Regulation of TNFR1 signaling; Negative regulators of DDX58/IFIH1 signaling","",8,0,0.965,-0.05,0.682165209088498,0.999610319815025,104.3,96.1,99.6,"",5.31,6.2,847.5,"","",796.2,777.8,706.3,785,904.9,793.4,817.9,800.8,43,"","",635.4,588.7,560.9,568.5,651.7,793.4,666.6,639,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q9H4A6","Golgi phosphoprotein 3 OS=Homo sapiens OX=9606 GN=GOLPH3 PE=1 SV=1",0,33.727,24,7,10,7,298,33.8,6.44,34.31,7,"cell organization and biogenesis;cell proliferation;cellular component movement;metabolic process;regulation of biological process;transport","cytosol;endosome;Golgi;membrane;mitochondrion","protein binding","Pf05719","64083","ENSG00000113384.13","GOLPH3","5","Transcriptional misregulation in cancer","","",1,0,1.025,0.04,0.771107916971215,0.999610319815025,205.8,47.7,46.5,119.53,4.78,8.65,1200.3,14309.7,"",882.2,944.2,978.3,978,884.4,835.6,996.3,993,60.9,4,"",704,714.7,776.9,708.3,637,835.6,812,792.4,"High","High","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q9C0I1","Myotubularin-related protein 12 OS=Homo sapiens OX=9606 GN=MTMR12 PE=1 SV=2",0,33.267,16,10,11,10,747,86.1,6.62,33.17,10,"metabolic process;regulation of biological process;transport","cytoplasm;cytosol","enzyme regulator activity;protein binding","Pf06602, Pf12578","54545","ENSG00000150712.10","MTMR12","5","","Synthesis of PIPs at the early endosome membrane","",5,0,1.006,0.01,0.947474453663173,0.999610319815025,174.6,62.9,62.5,118.36,2.62,1.79,825.8,9301.3,"",987.1,1026.4,966.3,1008.6,1014,994.9,989.4,970.7,41.9,2.6,"",787.7,776.9,767.3,730.5,730.3,994.9,806.4,774.6,"High","High","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q96QR8","Transcriptional activator protein Pur-beta OS=Homo sapiens OX=9606 GN=PURB PE=1 SV=3",0,32.309,32,8,11,7,312,33.2,5.43,33.32,8,"cell differentiation;cell proliferation;metabolic process;regulation of biological process","nucleus","DNA binding;protein binding;RNA binding","Pf04845","5814","ENSG00000146676.8","PURB","7","","","",0,0,1.04,0.06,0.666864452892801,0.999610319815025,107.3,98.2,94.4,"",1.83,3.54,2528.8,"","",2398.9,2315.2,2315,2310.8,2124.2,2213,2238.5,2314.9,128.3,"","",1914.3,1752.4,1838.3,1673.6,1529.9,2213,1824.4,1847.2,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q9Y3A4","Ribosomal RNA-processing protein 7 homolog A OS=Homo sapiens OX=9606 GN=RRP7A PE=1 SV=2",0,31.666,26,6,10,6,280,32.3,9.58,35.04,6,"cell organization and biogenesis;metabolic process","cytoplasm","protein binding;RNA binding","Pf00076, Pf12923","27341","ENSG00000189306.10","RRP7A","22","Ribosome biogenesis in eukaryotes","Major pathway of rRNA processing in the nucleolus and cytosol; rRNA modification in the nucleus and cytosol","",6,0,1.003,0,0.930383347816184,0.999610319815025,96.2,102,101.7,"",4.22,5.34,583.4,"","",618.2,618.6,640.2,578.1,665.2,631.9,591,602,29.6,"","",493.3,468.2,508.4,418.7,479.1,631.9,481.7,480.4,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q9H467","CUE domain-containing protein 2 OS=Homo sapiens OX=9606 GN=CUEDC2 PE=1 SV=1",0,30.965,21,6,8,6,287,32,4.81,23.79,6,"regulation of biological process","cytoplasm;cytosol;membrane;nucleus","protein binding","Pf02845","79004","ENSG00000107874.10","CUEDC2","10","","","Regulation of toll-like receptor signaling pathway",1,0,1.003,0,0.943307750661225,0.999610319815025,111.1,94.6,94.3,"",5.12,5.81,843.6,"","",727.6,708.8,733.5,654.2,750.7,719.3,712.4,652.2,42.8,"","",580.6,536.5,582.5,473.8,540.7,719.3,580.6,520.4,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q9BX69","Caspase recruitment domain-containing protein 6 OS=Homo sapiens OX=9606 GN=CARD6 PE=1 SV=2",0,30.495,7,6,6,6,1037,116.4,6.37,18.51,6,"cell death;regulation of biological process","","protein binding","Pf00619","84674","ENSG00000132357.13","CARD6","5","NOD-like receptor signaling pathway","","Nucleotide-binding Oligomerization Domain (NOD) pathway",2,0,1.022,0.03,0.820720664663782,0.999610319815025,67.8,117.4,114.8,"",7.03,3.99,199.1,"","",334,355.7,317.1,372.4,334.8,349.7,317.7,339.7,10.1,"","",266.5,269.2,251.8,269.7,241.1,349.7,258.9,271.1,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q96II8","DISP complex protein LRCH3 OS=Homo sapiens OX=9606 GN=LRCH3 PE=1 SV=2",0,29.747,11,7,7,7,777,86,6.71,18.26,7,"regulation of biological process;response to stimulus","cytosol;extracellular;membrane","protein binding","Pf00307, Pf12799, Pf13855","84859","ENSG00000186001.12","LRCH3","3","","","",0,0,1.017,0.02,0.789269843993366,0.999610319815025,67.2,117.4,115.4,"",8.8,3.53,138,"","",248.5,233.7,220,269.9,232,228.1,245.9,242.2,7,"","",198.3,176.9,174.7,195.5,167.1,228.1,200.4,193.3,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q8WVK2","U4/U6.U5 small nuclear ribonucleoprotein 27 kDa protein OS=Homo sapiens OX=9606 GN=SNRNP27 PE=1 SV=1",0,29.296,38,6,9,6,155,18.8,11.62,20.04,6,"metabolic process","nucleus","protein binding","Pf08648","11017","ENSG00000124380.10","SNRNP27","2","Spliceosome","mRNA Splicing - Major Pathway","",5,0,0.995,-0.01,0.980913880634515,0.999610319815025,100.4,99.5,100,"",5.13,2.92,814,"","",818.3,779.4,795.1,875.1,833.8,795,785.3,826.6,41.3,"","",653,589.9,631.4,633.8,600.5,795,640,659.6,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q86WX3","Active regulator of SIRT1 OS=Homo sapiens OX=9606 GN=RPS19BP1 PE=1 SV=1",0,28.729,32,6,10,6,136,15.4,10.74,28.98,6,"","cytosol;nucleus;ribosome","protein binding;RNA binding","","91582","ENSG00000187051.8","RPS19BP1","22","","Regulation of HSF1-mediated heat shock response","",4,0,1.017,0.02,0.840563759986111,0.999610319815025,163.1,69,67.8,102.65,2.89,0.71,1363.9,8585.8,"",1456.4,1439.2,1376.7,1470.9,1418.9,1440.8,1419.5,1426.6,69.2,2.4,"",1162.2,1089.3,1093.2,1065.3,1021.9,1440.8,1156.9,1138.4,"High","High","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q8N142","Adenylosuccinate synthetase isozyme 1 OS=Homo sapiens OX=9606 GN=ADSS1 PE=1 SV=1",0,28.326,20,7,8,7,457,50.2,8.59,23.83,7,"metabolic process;response to stimulus","cytoplasm;cytosol","catalytic activity;metal ion binding;nucleotide binding;protein binding","Pf00709","122622","ENSG00000185100.10","ADSSL1","14","Alanine, aspartate and glutamate metabolism; Metabolic pathways; Purine metabolism","Purine ribonucleoside monophosphate biosynthesis","",7,0,0.997,0,0.97465666262207,0.999610319815025,89.2,105.2,105.5,"",1.45,1.37,386.3,"","",463.5,452.1,458.9,448.9,466.7,452.1,455.2,458.4,19.6,"","",369.9,342.2,364.4,325.1,336.1,452.1,371,365.8,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P09417","Dihydropteridine reductase OS=Homo sapiens OX=9606 GN=QDPR PE=1 SV=2",0,27.482,28,8,10,8,244,25.8,7.37,22.86,8,"metabolic process;response to stimulus","cytoplasm;cytosol;mitochondrion","catalytic activity;nucleotide binding;protein binding","","5860","ENSG00000151552.11","QDPR","4","Folate biosynthesis; Metabolic pathways","Phenylalanine and tyrosine catabolism","",6,0,1.031,0.04,0.687470879515492,0.999610319815025,99.7,101.7,98.6,"",1.1,1.96,1310.7,"","",1337.8,1345.6,1311.6,1335.3,1327.8,1278.3,1277.5,1314.3,66.5,"","",1067.6,1018.5,1041.5,967.1,956.3,1278.3,1041.2,1048.8,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q16875","6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 OS=Homo sapiens OX=9606 GN=PFKFB3 PE=1 SV=1",0,26.895,20,10,11,7,520,59.6,8.21,30.57,10,"metabolic process;regulation of biological process","cytosol","catalytic activity;nucleotide binding","Pf00300, Pf01591, Pf13207, Pf13671","5209","ENSG00000170525.19","PFKFB3","10","Fructose and mannose metabolism; AMPK signaling pathway; HIF-1 signaling pathway","Glycolysis","AMP-activated Protein Kinase (AMPK) Signaling; Focal Adhesion-PI3K-Akt-mTOR-signaling pathway",9,1,1.009,0.01,0.924116798997405,0.999610319815025,97.5,101.7,100.8,"",8.6,2.33,368.6,"","",429.3,362.9,406.9,361.5,381.5,364.9,384.7,380.1,18.7,"","",342.6,274.7,323.1,261.8,274.8,364.9,313.5,303.3,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q9NUP9","Protein lin-7 homolog C OS=Homo sapiens OX=9606 GN=LIN7C PE=1 SV=1",0,26.49,41,8,12,8,197,21.8,8.43,31.84,8,"cell organization and biogenesis;transport","cytoplasm;membrane","protein binding","Pf00595, Pf02828, Pf09829","55327","ENSG00000148943.11","LIN7C","11","","Dopamine Neurotransmitter Release Cycle; Neurexins and neuroligins","",6,0,0.979,-0.03,0.689174978079163,0.999610319815025,90.2,103.8,106,"",2.6,1.94,936.2,"","",1071.8,1092.2,1081.7,1028.9,1101.9,1102.1,1098,1058.4,47.5,"","",855.3,826.7,859,745.2,793.6,1102.1,894.9,844.6,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q07912","Activated CDC42 kinase 1 OS=Homo sapiens OX=9606 GN=TNK2 PE=1 SV=3",0,26.239,8,6,7,6,1038,114.5,7.25,21.18,6,"cell differentiation;cellular component movement;defense response;metabolic process;regulation of biological process;response to stimulus;transport","cytoplasm;endosome;membrane;nucleus","catalytic activity;enzyme regulator activity;metal ion binding;nucleotide binding;protein binding","Pf00018, Pf00069, Pf07653, Pf07714, Pf09027, Pf11555, Pf14531, Pf14604","10188","ENSG00000061938.16","TNK2","3","","","Focal Adhesion; Oxidative Damage; EGF/EGFR Signaling Pathway; G13 Signaling Pathway",4,0,0.98,-0.03,0.941576199336525,0.999610319815025,74.2,111.8,114,"",4.45,2.76,71,"","",105.5,108.3,99.9,110.9,104,110.9,109.4,108.7,3.6,"","",84.2,82,79.3,80.3,74.9,110.9,89.2,86.7,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q9Y324","rRNA-processing protein FCF1 homolog OS=Homo sapiens OX=9606 GN=FCF1 PE=2 SV=1",0,25.638,20,6,10,6,198,23.4,9.7,28.01,6,"metabolic process","nucleus","RNA binding","Pf04900","51077","ENSG00000119616.11","FCF1","14","Ribosome biogenesis in eukaryotes","Major pathway of rRNA processing in the nucleolus and cytosol; rRNA modification in the nucleus and cytosol","",6,0,0.971,-0.04,0.681729708712694,0.999610319815025,97.3,99.8,102.9,"",14.28,11.55,920.5,"","",988,902.9,1008.4,724.3,794.3,962.6,1052.4,983.7,46.7,"","",788.4,683.4,800.8,524.6,572.1,962.6,857.7,785,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q9H6Y7","E3 ubiquitin-protein ligase RNF167 OS=Homo sapiens OX=9606 GN=RNF167 PE=1 SV=1",0,25.083,16,4,6,4,350,38.3,5.63,18.42,4,"metabolic process;regulation of biological process","cytoplasm;membrane","catalytic activity;metal ion binding;protein binding","Pf00097, Pf02225, Pf12678, Pf12861, Pf13639, Pf13920, Pf13923, Pf14634","26001","ENSG00000108523.15","RNF167","17","","","",0,0,0.999,0,0.985997777094039,0.999610319815025,107.8,96.1,96.1,"",4.44,6.57,1097.8,"","",953.1,1022.3,929.6,1004.9,935.3,968.2,990.8,1087.4,55.7,"","",760.6,773.8,738.2,727.8,673.6,968.2,807.5,867.7,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q6H8Q1","Actin-binding LIM protein 2 OS=Homo sapiens OX=9606 GN=ABLIM2 PE=1 SV=2",0,24.405,14,6,6,6,611,67.8,7.94,20.95,6,"cell organization and biogenesis;metabolic process","cytoplasm;cytoskeleton","metal ion binding;protein binding","Pf00412, Pf02209","84448","ENSG00000163995.19","ABLIM2","4","Axon guidance","DCC mediated attractive signaling","",5,0,0.97,-0.04,0.81731433113305,0.999610319815025,96.6,100.1,103.3,"",3.06,5.01,214.8,"","",211.4,226.6,220.6,224.6,229.6,229.6,229.9,207.3,10.9,"","",168.7,171.5,175.2,162.7,165.4,229.6,187.4,165.4,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q6DKI1","60S ribosomal protein L7-like 1 OS=Homo sapiens OX=9606 GN=RPL7L1 PE=1 SV=2",0,23.927,22,6,12,6,255,29.7,10.52,26.73,6,"","","","","","","","","","","",0,0,1,0,0.959938069804194,0.999610319815025,188,56,56,122.12,1.86,2.16,812,11090,"",882.7,900.3,920,887.5,920.1,879.3,882.6,905.5,41.2,3.1,"",704.4,681.4,730.6,642.8,662.7,879.3,719.3,722.6,"High","High","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q00722","1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2 OS=Homo sapiens OX=9606 GN=PLCB2 PE=1 SV=2",0,23.402,8,8,8,8,1185,133.9,6.29,21.29,8,"cellular component movement;metabolic process;regulation of biological process;response to stimulus;transport","cytoplasm;cytosol;extracellular","catalytic activity;metal ion binding;protein binding;signal transducer activity","Pf00168, Pf00387, Pf00388, Pf00769, Pf01442, Pf02463, Pf08703, Pf09279, Pf09731, Pf10174, Pf12474, Pf13851, Pf13868, Pf15346","5330","ENSG00000137841.11","PLCB2","15","Rap1 signaling pathway; Pancreatic secretion; Cholinergic synapse; Glutamatergic synapse; AGE-RAGE signaling pathway in diabetic complications; Inflammatory mediator regulation of TRP channels; Serotonergic synapse; Insulin secretion; Retrograde endocannabinoid signaling; Circadian entrainment; Wnt signaling pathway; African trypanosomiasis; Renin secretion; Glucagon signaling pathway; Chemokine signaling pathway; NOD-like receptor signaling pathway; Phosphatidylinositol signaling system; Gastric acid secretion; Dopaminergic synapse; Long-term potentiation; Long-term depression; Phospholipase D signaling pathway; Taste transduction; GnRH signaling pathway; Endocrine and other factor-regulated calcium reabsorption; Alzheimer's disease; Platelet activation; Vascular smooth muscle contraction; Adrenergic signaling in cardiomyocytes; Salivary secretion; Oxytocin signaling pathway; Melanogenesis; Calcium signaling pathway; Amoebiasis; Gap junction; Sphingolipid signaling pathway; Huntington's disease; Thyroid hormone synthesis; Estrogen signaling pathway; Chagas disease (American trypanosomiasis); Thyroid hormone signaling pathway; Aldosterone synthesis and secretion; cGMP-PKG signaling pathway; Inositol phosphate metabolism; Metabolic pathways; Pathways in cancer; Carbohydrate digestion and absorption","PLC beta mediated events; Acetylcholine regulates insulin secretion; Ca2+ pathway; Presynaptic function of Kainate receptors; G beta:gamma signalling through PLC beta; Synthesis of IP3 and IP4 in the cytosol; Gastrin-CREB signalling pathway via PKC and MAPK; Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion","MicroRNAs in cardiomyocyte hypertrophy; Alzheimers Disease; Signal Transduction of S1P Receptor; Chemokine signaling pathway; GPR40 PATHWAY",78,0,0.974,-0.04,0.857843939334446,0.999610319815025,"",148,152,"",13.12,3.18,"","","",33.2,35.8,44.7,37,36.2,36.4,38.4,38.3,"","","",26.5,27.1,35.5,26.8,26.1,36.4,31.3,30.6,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q12974","Protein tyrosine phosphatase type IVA 2 OS=Homo sapiens OX=9606 GN=PTP4A2 PE=1 SV=1",0,22.914,34,5,9,1,167,19.1,8.37,26.5,5,"metabolic process","cytoplasm;cytosol;endosome;membrane;nucleus","catalytic activity","Pf00102, Pf00782","8073","ENSG00000184007.18","PTP4A2","1","","RAB geranylgeranylation","",3,0,0.984,-0.02,0.92647421135171,0.999610319815025,101.4,98.5,100.1,"",2.65,6.3,173.4,"","",168.3,168.1,177.4,168.9,181.5,163.9,160,179.2,8.8,"","",134.3,127.2,140.9,122.3,130.7,163.9,130.4,143,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q9NP97","Dynein light chain roadblock-type 1 OS=Homo sapiens OX=9606 GN=DYNLRB1 PE=1 SV=3",0,22.255,44,4,7,4,96,10.9,7.25,22.36,4,"cellular component movement;response to stimulus;transport","cytoplasm;cytoskeleton;membrane","catalytic activity;motor activity;protein binding","Pf03259","83658","ENSG00000125971.16","DYNLRB1","20","","Intraflagellar transport","",3,0,0.988,-0.02,0.778984236006529,0.999610319815025,105.3,96.7,97.9,"",4.22,6.93,2152.3,"","",1995,1957.9,1828.9,2009.8,1950.6,1793.9,2052.2,2105.1,109.2,"","",1592,1481.9,1452.3,1455.6,1404.9,1793.9,1672.6,1679.8,"High","High","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q8IWB7","WD repeat and FYVE domain-containing protein 1 OS=Homo sapiens OX=9606 GN=WDFY1 PE=1 SV=1",0,21.77,15,5,6,5,410,46.3,7.33,19.41,5,"regulation of biological process","cytosol;endosome;nucleus","metal ion binding;protein binding","Pf00400, Pf01363","57590","ENSG00000085449.14","WDFY1","2","","","",0,0,0.959,-0.06,0.765568051172278,0.999610319815025,65.9,114.6,119.5,"",6.77,2.58,132.1,"","",229.6,229.4,250.9,212.8,233.3,244.3,244.5,234.2,6.7,"","",183.2,173.6,199.2,154.1,168,244.3,199.3,186.9,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q14019","Coactosin-like protein OS=Homo sapiens OX=9606 GN=COTL1 PE=1 SV=3",0,21.258,50,6,16,6,142,15.9,5.67,38.42,6,"defense response;response to stimulus;transport","cytoplasm;cytoskeleton;extracellular;nucleus;organelle lumen","protein binding","Pf00241, Pf01453","23406","ENSG00000103187.7","COTL1","16","","Neutrophil degranulation","",3,0,1.025,0.04,0.803998511863471,0.999610319815025,93.4,104.6,102,"",4.99,2.52,2580,"","",2872.5,2906.7,2637.1,2957.7,2878,2795.3,2713.8,2841.2,130.9,"","",2292.3,2200.1,2094.1,2142.1,2072.8,2795.3,2211.8,2267.2,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q96EY5","Multivesicular body subunit 12A OS=Homo sapiens OX=9606 GN=MVB12A PE=1 SV=1",0,20.685,22,4,4,4,273,28.8,8.91,14.5,4,"cell communication;cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus;transport","cytoplasm;cytoskeleton;cytosol;endosome;Golgi;membrane;nucleus","protein binding","Pf10240","93343","ENSG00000141971.12","FAM125A; MVB12A","19","Endocytosis","Budding and maturation of HIV virion; Endosomal Sorting Complex Required For Transport (ESCRT); Membrane binding and targetting of GAG proteins","",13,0,1.016,0.02,0.831864284481047,0.999610319815025,104.3,98.6,97.1,"",2.19,3.46,609,"","",561.5,587.8,567.9,584.1,562.7,532.7,570.8,576.2,30.9,"","",448.1,444.9,451,423,405.3,532.7,465.2,459.8,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q9UEE9","Craniofacial development protein 1 OS=Homo sapiens OX=9606 GN=CFDP1 PE=1 SV=1",0,20.246,19,4,6,4,299,33.6,4.81,7.22,4,"development;regulation of biological process","chromosome","","Pf07572","10428","ENSG00000153774.8","CFDP1","16","","","",0,0,1.026,0.04,0.736426254832562,0.999610319815025,109.8,96.3,93.9,"",5.69,5.7,983.5,"","",894,833.4,825.2,928.6,859.3,818.6,824.3,924.8,49.9,"","",713.4,630.8,655.3,672.5,618.9,818.6,671.8,738,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q9Y2R0","Cytochrome c oxidase assembly factor 3 homolog, mitochondrial OS=Homo sapiens OX=9606 GN=COA3 PE=1 SV=1",0,19.79,27,3,8,3,106,11.7,9.6,19.32,3,"cell organization and biogenesis;regulation of biological process","membrane;mitochondrion","protein binding","Pf09813","28958","ENSG00000183978.7","COA3","17","","","",0,0,1.009,0.01,0.873948765314932,0.999610319815025,92.1,104.4,103.5,"",3.77,5.06,595.2,"","",691.3,681.5,668.8,633.6,668.1,669.5,675.3,605,30.2,"","",551.7,515.8,531.1,458.9,481.2,669.5,550.4,482.8,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q96QT4","Transient receptor potential cation channel subfamily M member 7 OS=Homo sapiens OX=9606 GN=TRPM7 PE=1 SV=1",0,19.467,4,7,7,7,1865,212.6,7.88,22.16,7,"cell death;cell organization and biogenesis;cellular homeostasis;metabolic process;transport","membrane","catalytic activity;metal ion binding;nucleotide binding;protein binding;transporter activity","Pf00520, Pf02816","54822","ENSG00000092439.13","TRPM7","15","NOD-like receptor signaling pathway; Mineral absorption","TRP channels","",6,0,1.031,0.04,0.773041766782707,0.999610319815025,92.9,105.2,102,"",6.43,7.64,319.3,"","",365.7,357.6,374.8,322.5,360.2,360.4,341.5,304.9,16.2,"","",291.8,270.7,297.6,233.6,259.4,360.4,278.3,243.3,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q96AT9","Ribulose-phosphate 3-epimerase OS=Homo sapiens OX=9606 GN=RPE PE=1 SV=1",0,18.832,22,4,6,4,228,24.9,5.58,20.59,4,"metabolic process","cytosol","catalytic activity;metal ion binding;protein binding","Pf00218, Pf00834, Pf01729","6120","ENSG00000197713.14","RPE","2","Pentose phosphate pathway; Pentose and glucuronate interconversions; Metabolic pathways; Biosynthesis of amino acids; Carbon metabolism","Pentose phosphate pathway (hexose monophosphate shunt)","Pentose Phosphate Pathway",9,0,1.011,0.02,0.863118825809981,0.999610319815025,96.9,102.1,101,"",3.29,5.64,904.7,"","",900.7,964.3,968.6,941.4,979.8,965.1,919.6,863.1,45.9,"","",718.8,729.9,769.2,681.8,705.7,965.1,749.5,688.7,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q86YV9","Hermansky-Pudlak syndrome 6 protein OS=Homo sapiens OX=9606 GN=HPS6 PE=1 SV=1",0,18.434,8,6,8,6,775,82.9,6.28,20.98,6,"cell differentiation;cell organization and biogenesis;coagulation","cytoplasm;cytosol;endoplasmic reticulum;endosome;membrane;vacuole","protein binding","","79803","ENSG00000166189.7","HPS6","10","","","",0,0,0.965,-0.05,0.739198928867175,0.999610319815025,101.3,97.6,101.1,"",8.44,1.69,283.8,"","",279.8,303.6,267.1,248.4,283.7,274.5,282.9,285,14.4,"","",223.3,229.8,212.1,179.9,204.3,274.5,230.6,227.4,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P06746","DNA polymerase beta OS=Homo sapiens OX=9606 GN=POLB PE=1 SV=3",0,18.433,20,7,8,6,335,38.2,8.95,21.42,7,"cell death;defense response;metabolic process;regulation of biological process;response to stimulus","cytoplasm;nucleus","catalytic activity;DNA binding;metal ion binding;protein binding","Pf10391, Pf14520, Pf14716, Pf14791, Pf14792","5423","ENSG00000070501.11","POLB","8","Base excision repair; HTLV-I infection; Viral carcinogenesis","APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway; POLB-Dependent Long Patch Base Excision Repair; PCNA-Dependent Long Patch Base Excision Repair; Ub-specific processing proteases; Abasic sugar-phosphate removal via the single-nucleotide replacement pathway","Nucleotide Metabolism",17,0,0.992,-0.01,0.918265513669237,0.999610319815025,105.2,97,97.8,"",2.96,4.43,530.2,"","",484.2,479.5,493.4,512.4,483.9,516.4,466,501.5,26.9,"","",386.4,362.9,391.8,371.1,348.5,516.4,379.8,400.2,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q709F0","Acyl-CoA dehydrogenase family member 11 OS=Homo sapiens OX=9606 GN=ACAD11 PE=1 SV=3",0,18.085,8,6,7,6,780,87.2,8.02,20.21,6,"","","","","","","","","","","",0,0,0.969,-0.05,0.690656037454507,0.999610319815025,97.9,99.5,102.6,"",4.65,2.92,546,"","",551.9,551.5,606,557.4,567.9,576.9,601.6,564.1,27.7,"","",440.4,417.4,481.2,403.7,409,576.9,490.3,450.1,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q9H8H3","Methyltransferase-like protein 7A OS=Homo sapiens OX=9606 GN=METTL7A PE=1 SV=1",0,17.604,22,4,4,4,244,28.3,8.38,12.99,4,"metabolic process;transport","endoplasmic reticulum;extracellular;membrane","catalytic activity","Pf01209, Pf01739, Pf05148, Pf05175, Pf08241, Pf08242, Pf12847, Pf13489, Pf13649, Pf13659, Pf13847","25840","ENSG00000185432.11","METTL7A","12","","Neutrophil degranulation","",3,0,1.033,0.05,0.736129631137837,0.999610319815025,101.6,100.8,97.6,"",6.11,11.12,404.1,"","",409,393.2,424.1,367.1,322,394.6,381.7,422.2,20.5,"","",326.4,297.6,336.8,265.9,231.9,394.6,311.1,336.9,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q96NL6","Sodium channel and clathrin linker 1 OS=Homo sapiens OX=9606 GN=SCLT1 PE=1 SV=2",0,17.294,10,7,7,7,688,80.9,6.07,19.97,7,"cell organization and biogenesis;transport","cytoplasm;cytoskeleton;cytosol","protein binding;transporter activity","Pf01496, Pf05478, Pf12128","132320","ENSG00000151466.11","SCLT1","4","","Anchoring of the basal body to the plasma membrane","",3,0,0.999,0,0.980404835891933,0.999610319815025,94,102.9,103,"",1.56,2.76,480.9,"","",530.3,528.5,524.2,512.1,540.5,528,525.9,505.5,24.4,"","",423.2,400,416.3,370.9,389.3,528,428.6,403.4,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P53680","AP-2 complex subunit sigma OS=Homo sapiens OX=9606 GN=AP2S1 PE=1 SV=2",0,16.927,24,4,6,4,142,17,6.18,13.73,4,"cell organization and biogenesis;cellular component movement;metabolic process;regulation of biological process;response to stimulus;transport","cytosol;membrane","protein binding;transporter activity","Pf01217","1175","ENSG00000042753.11","AP2S1","19","Endocytosis; Synaptic vesicle cycle; Huntington's disease; Endocrine and other factor-regulated calcium reabsorption","Cargo recognition for clathrin-mediated endocytosis; Nef Mediated CD8 Down-regulation; Nef Mediated CD4 Down-regulation; Trafficking of GluR2-containing AMPA receptors; Recycling pathway of L1; LDL clearance; EPH-ephrin mediated repulsion of cells; Retrograde neurotrophin signalling; VLDLR internalisation and degradation; WNT5A-dependent internalization of FZD2, FZD5 and ROR2; MHC class II antigen presentation; WNT5A-dependent internalization of FZD4","Synaptic Vesicle Pathway; EGF/EGFR Signaling Pathway",48,0,1.029,0.04,0.702254804132374,0.999610319815025,86.7,108.2,105.1,"",4.58,5.13,433.6,"","",524.8,559.7,557.4,509.6,545,558.1,503.9,507.2,22,"","",418.8,423.6,442.6,369.1,392.5,558.1,410.7,404.7,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q9UKA9","Polypyrimidine tract-binding protein 2 OS=Homo sapiens OX=9606 GN=PTBP2 PE=1 SV=1",0,16.574,8,3,3,3,531,57.5,8.66,10.83,3,"cell organization and biogenesis;metabolic process;regulation of biological process","nucleus;spliceosomal complex","RNA binding","Pf00076, Pf13893, Pf14259","58155","ENSG00000117569.18","PTBP2","1","","","TarBasePathway; mRNA Processing",2,0,0.968,-0.05,0.742776015398389,0.999610319815025,32.8,131.4,135.8,"",6.59,1.63,71,"","",284.1,288.3,284.5,249.4,294.6,291.6,302.3,292.9,3.6,"","",226.7,218.2,225.9,180.6,212.2,291.6,246.4,233.7,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P26572","Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase OS=Homo sapiens OX=9606 GN=MGAT1 PE=1 SV=2",0,16.297,12,5,5,5,445,50.8,9.16,10.97,5,"metabolic process","Golgi;membrane","catalytic activity;metal ion binding","Pf03071","4245","ENSG00000131446.16","MGAT1","5","N-Glycan biosynthesis; Metabolic pathways","N-glycan trimming and elongation in the cis-Golgi","",7,0,1,0,0.963625061704089,0.999610319815025,91.1,104.5,104.5,"",3.9,7.2,317.3,"","",362.9,376.3,365.2,342.4,363.5,368.8,364.7,315,16.1,"","",289.6,284.8,290,248,261.8,368.8,297.2,251.4,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q9HAC8","Ubiquitin domain-containing protein 1 OS=Homo sapiens OX=9606 GN=UBTD1 PE=1 SV=1",0,16.038,19,4,5,1,227,25.9,7.83,10.33,4,"","","protein binding","Pf00240, Pf11976","80019","ENSG00000165886.4","UBTD1","10","","","",0,0,1.001,0,0.9686395728737,0.999610319815025,148,76,76,"",7.49,11.34,63.1,"","",36.2,31.2,33.6,30.9,30.3,34.6,35.3,27.7,3.2,"","",28.9,23.6,26.7,22.4,21.8,34.6,28.8,22.1,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q3SXY8","ADP-ribosylation factor-like protein 13B OS=Homo sapiens OX=9606 GN=ARL13B PE=1 SV=1",0,15.69,14,5,5,5,428,48.6,6.62,15.16,5,"cell organization and biogenesis;cellular component movement;regulation of biological process;response to stimulus","membrane","catalytic activity;nucleotide binding;protein binding;signal transducer activity","Pf00009, Pf00025, Pf00071, Pf00503, Pf01926, Pf05890, Pf07946, Pf08477, Pf09439","200894","ENSG00000169379.15","ARL13B","3","","ARL13B-mediated ciliary trafficking of INPP5E","",4,0,0.964,-0.05,0.745381495037739,0.999610319815025,87.6,104.2,108.2,"",2.06,7.09,163.6,"","",195.9,193.4,192.9,201.7,214.4,201.1,180.4,202.9,8.3,"","",156.3,146.4,153.2,146.1,154.4,201.1,147,161.9,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q8NEZ3","WD repeat-containing protein 19 OS=Homo sapiens OX=9606 GN=WDR19 PE=1 SV=2",0,15.138,3,4,4,4,1342,151.5,6.35,12.66,4,"cell organization and biogenesis;cellular component movement;metabolic process;regulation of biological process;response to stimulus;transport","cytoplasm;cytoskeleton","protein binding","Pf04762","57728","ENSG00000157796.17","WDR19","4","","Hedgehog 'off' state; Intraflagellar transport","",6,0,0.948,-0.08,0.659990063401313,0.999610319815025,75.5,109.2,115.2,"",5.89,3.03,100.5,"","",142.4,137.5,148.5,157.5,155,156.6,146.1,151.8,5.1,"","",113.6,104.1,117.9,114.1,111.6,156.6,119.1,121.1,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q58EX7","Puratrophin-1 OS=Homo sapiens OX=9606 GN=PLEKHG4 PE=1 SV=1",0,14.901,3,5,6,5,1191,130.7,5.64,17.06,5,"regulation of biological process","","protein binding","Pf00621, Pf13716","25894","ENSG00000196155.12","PLEKHG4","16","","","",0,0,1.016,0.02,0.809037023569576,0.999610319815025,61.2,120.3,118.5,"",14.49,11.86,55.2,"","",103.8,113.4,119.1,84.4,97.5,112.3,126.5,101.5,2.8,"","",82.8,85.8,94.6,61.1,70.2,112.3,103.1,81,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","O96033","Molybdopterin synthase sulfur carrier subunit OS=Homo sapiens OX=9606 GN=MOCS2 PE=1 SV=1",0,14.321,45,4,5,4,88,9.7,4.72,13.42,4,"metabolic process","cytoplasm;cytosol;nucleus","catalytic activity;nucleotide binding","Pf02597","4338","ENSG00000164172.18","MOCS2","5","","Molybdenum cofactor biosynthesis","",4,0,1.028,0.04,0.688049482478071,0.999610319815025,93.3,104.8,101.9,"",7.03,1.89,729.3,"","",820.8,791,816.8,924.4,817.2,780.9,793.6,799.3,37,"","",655,598.7,648.6,669.5,588.6,780.9,646.8,637.8,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q5RI15","Cytochrome c oxidase assembly protein COX20, mitochondrial OS=Homo sapiens OX=9606 GN=COX20 PE=1 SV=2",0,13.894,23,3,5,3,118,13.3,8.76,16.27,3,"cell organization and biogenesis;metabolic process","membrane;mitochondrion","","Pf12597","116228","ENSG00000203667.9","COX20","1","","TP53 Regulates Metabolic Genes; Respiratory electron transport","",9,0,1.022,0.03,0.751347350755586,0.999610319815025,97.8,102.2,100,"",3.41,3.34,682,"","",731.1,677.9,724.6,701.8,681,729,712.8,682.9,34.6,"","",583.4,513.1,575.4,508.3,490.5,729,580.9,544.9,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q8TEQ0","Sorting nexin-29 OS=Homo sapiens OX=9606 GN=SNX29 PE=1 SV=3",0,13.277,6,4,4,3,813,91.2,6.21,13.13,4,"","","","Pf00787, Pf02759","92017","ENSG00000048471.13","SNX29","16","","","",0,1,0.948,-0.08,0.70430456796722,0.999610319815025,"",146,154,"",6.33,4.39,"","","",84.7,85,93.6,80.6,86.2,87.2,94.6,91.9,"","","",67.6,64.3,74.3,58.4,62.1,87.2,77.1,73.3,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P49406","39S ribosomal protein L19, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL19 PE=1 SV=2",0,12.898,13,4,5,4,292,33.5,9.5,13.38,4,"cell organization and biogenesis;metabolic process","membrane;mitochondrion;nucleus;ribosome","structural molecule activity","Pf01245","9801","ENSG00000115364.13","MRPL19","2","Ribosome","Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination","Cytoplasmic Ribosomal Proteins",8,0,0.987,-0.02,0.8700526340784,0.999610319815025,94.2,102.2,103.6,"",2.93,4.59,417.8,"","",463.7,446.6,460.5,435.1,425.4,452.3,466.6,471.9,21.2,"","",370,338,365.7,315.1,306.4,452.3,380.3,376.6,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q9Y478","5'-AMP-activated protein kinase subunit beta-1 OS=Homo sapiens OX=9606 GN=PRKAB1 PE=1 SV=4",0,12.482,18,3,3,3,270,30.4,6.4,8.12,3,"cell communication;cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus","cytosol;nucleus","catalytic activity;protein binding","Pf02922, Pf04739","5564","ENSG00000111725.10","PRKAB1","12","Adipocytokine signaling pathway; Non-alcoholic fatty liver disease (NAFLD); Oxytocin signaling pathway; Longevity regulating pathway - multiple species; Longevity regulating pathway; Circadian rhythm; Glucagon signaling pathway; Insulin signaling pathway; Hypertrophic cardiomyopathy (HCM); Insulin resistance; AMPK signaling pathway; FoxO signaling pathway","Translocation of GLUT4 to the plasma membrane; Energy dependent regulation of mTOR by LKB1-AMPK; TP53 Regulates Metabolic Genes; Regulation of TP53 Activity through Phosphorylation; Macroautophagy; Activation of PPARGC1A (PGC-1alpha) by phosphorylation","AMP-activated Protein Kinase (AMPK) Signaling; Target Of Rapamycin (TOR) Signaling; Energy Metabolism; Sterol Regulatory Element-Binding Proteins (SREBP) signalling; Factors and pathways affecting insulin-like growth factor (IGF1)-Akt signaling; Angiopoietin Like Protein 8 Regulatory Pathway; Leptin and adiponectin",37,0,1.028,0.04,0.806589977213495,0.999610319815025,111.4,95.6,93,"",4.9,5.74,417.8,"","",367.7,349.6,345.3,383.8,351.4,323.7,346.4,372.4,21.2,"","",293.4,264.6,274.2,278,253.1,323.7,282.3,297.2,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","C9JLW8","Mapk-regulated corepressor-interacting protein 1 OS=Homo sapiens OX=9606 GN=MCRIP1 PE=1 SV=1",0,12.374,30,2,3,2,97,10.9,9.41,9.18,2,"regulation of biological process","cytoplasm;nucleus","protein binding","Pf14799","348262","ENSG00000225663.7","FAM195B; MCRIP1","17","","","",0,0,0.972,-0.04,0.851845013342071,0.999610319815025,"",147.9,152.1,"",19.85,11.55,"","","",83.8,86.4,71.4,54.3,74.6,67,84.9,86,"","","",66.9,65.4,56.7,39.3,53.7,67,69.2,68.6,"Not Found","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q9UIF7-2","Isoform Alpha-2 of Adenine DNA glycosylase OS=Homo sapiens OX=9606 GN=MUTYH",0,12.064,8,3,3,3,536,59.1,8.85,7.59,3,"metabolic process;response to stimulus","mitochondrion;nucleus","catalytic activity;DNA binding;metal ion binding;protein binding","Pf00293, Pf00633, Pf00730, Pf10576, Pf14815","4595","ENSG00000132781.17","MUTYH","1","","","",0,0,1.004,0.01,0.908688973797381,0.999610319815025,93.8,103.3,102.9,"",12.7,6.94,134,"","",150.2,144.8,156.7,115.8,149.8,145.2,148.7,128.5,6.8,"","",119.9,109.6,124.4,83.9,107.9,145.2,121.2,102.5,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q6NW29","RWD domain-containing protein 4 OS=Homo sapiens OX=9606 GN=RWDD4 PE=1 SV=3",0,11.597,11,2,2,2,188,21.2,5.31,8.43,2,"","","protein binding","Pf05773","201965","ENSG00000182552.14","RWDD4","4","","","",0,0,0.961,-0.06,0.755897810384619,0.999610319815025,71.7,111.9,116.4,"",18.11,16.12,98.5,"","",159.5,148.4,179.3,114.3,127.9,149.3,186.3,171.7,5,"","",127.3,112.3,142.4,82.8,92.1,149.3,151.8,137,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q99766","ATP synthase subunit s, mitochondrial OS=Homo sapiens OX=9606 GN=DMAC2L PE=1 SV=3",0,11.107,15,3,3,3,215,24.9,7.56,10.09,3,"cell organization and biogenesis;metabolic process;transport","membrane;mitochondrion","metal ion binding;transporter activity","","27109","ENSG00000125375.14","ATP5S","14","","Cristae formation; Formation of ATP by chemiosmotic coupling","Electron Transport Chain; Oxidative phosphorylation",9,0,1.003,0,0.941317314124802,0.999610319815025,104.2,98,97.8,"",1.92,2.85,689.8,"","",629.3,657.9,646,652.7,660.1,635.4,627,664.8,35,"","",502.2,498,513,472.7,475.4,635.4,511,530.5,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q9BQF6","Sentrin-specific protease 7 OS=Homo sapiens OX=9606 GN=SENP7 PE=1 SV=4",0,10.71,3,3,3,3,1050,119.6,6.61,10.38,3,"metabolic process;regulation of biological process;response to stimulus","membrane;nucleus","catalytic activity;protein binding;receptor activity;signal transducer activity","Pf02902","57337","ENSG00000138468.15","SENP7","3","","","",0,0,0.973,-0.04,0.854587029814541,0.999610319815025,93.9,101.6,104.4,"",9.6,6.77,71,"","",76.6,77,82.1,65,76.8,73.9,86.3,81.1,3.6,"","",61.1,58.3,65.2,47.1,55.3,73.9,70.3,64.7,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","O14513","Nck-associated protein 5 OS=Homo sapiens OX=9606 GN=NCKAP5 PE=1 SV=2",0,9.962,2,4,4,4,1909,208.4,8.07,8.64,4,"","","","Pf15246","344148","ENSG00000176771.16","NCKAP5","2","","","",0,0,0.953,-0.07,0.722431061410103,0.999610319815025,47.8,123,129.2,"",2.91,9.45,51.2,"","",131.7,127.5,136.9,132.3,118.2,135.1,147.7,142.1,2.6,"","",105.1,96.5,108.7,95.8,85.1,135.1,120.4,113.4,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q5T2D3","OTU domain-containing protein 3 OS=Homo sapiens OX=9606 GN=OTUD3 PE=1 SV=1",0,9.643,11,4,4,4,398,45.1,8.29,12.2,4,"metabolic process;regulation of biological process","cytoplasm;cytosol","catalytic activity;protein binding","Pf02338","23252","ENSG00000169914.5","OTUD3","1","","Regulation of PTEN stability and activity; Ovarian tumor domain proteases","",9,0,0.946,-0.08,0.65508094410771,0.999610319815025,"",145.8,154.2,"",5.29,6.2,"","","",64.4,61.4,68.5,61.3,72.5,68.3,63.1,64.8,"","","",51.4,46.5,54.4,44.4,52.2,68.3,51.4,51.7,"Not Found","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q9HD23","Magnesium transporter MRS2 homolog, mitochondrial OS=Homo sapiens OX=9606 GN=MRS2 PE=1 SV=1",0,9.325,7,4,4,4,443,50.3,6.87,10.82,4,"metabolic process;transport","membrane;mitochondrion","transporter activity","","57380","ENSG00000124532.14","MRS2","6","","Miscellaneous transport and binding events","",2,0,1.023,0.03,0.75355293467054,0.999610319815025,106.8,97.7,95.5,"",5.54,2.59,577.5,"","",523.4,553,533.6,484.1,524.7,534.3,506.4,508.2,29.3,"","",417.7,418.6,423.7,350.6,377.9,534.3,412.7,405.5,"High","High","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q7Z5U6","WD repeat-containing protein 53 OS=Homo sapiens OX=9606 GN=WDR53 PE=2 SV=1",0,9.042,8,2,2,2,358,39,6.52,6.67,2,"","cytoplasm","protein binding","Pf00400","348793","ENSG00000185798.7","WDR53","3","","","",0,0,1.047,0.07,0.688331351717955,0.999610319815025,194.1,54.2,51.7,"",12.85,12.68,96.6,"","",23.8,27.2,26.7,32.3,22.1,24.7,29.8,26.8,4.9,"","",19,20.6,21.2,23.4,15.9,24.7,24.3,21.4,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q9NQ31","A-kinase-interacting protein 1 OS=Homo sapiens OX=9606 GN=AKIP1 PE=1 SV=2",0,8.767,8,1,1,1,210,23.1,8.16,4.71,1,"cell organization and biogenesis;regulation of biological process","nucleus","protein binding","","56672","ENSG00000166452.11","AKIP1","11","","","",0,0,1.02,0.03,0.836215145109208,0.999610319815025,"",151.5,148.5,"",7.17,5.51,"","","",25.2,21.5,24.9,23.2,23.3,21.2,23.9,23.8,"","","",20.1,16.3,19.8,16.8,16.8,21.2,19.5,19,"Not Found","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","O94876","Transmembrane and coiled-coil domains protein 1 OS=Homo sapiens OX=9606 GN=TMCC1 PE=1 SV=3",0,8.384,4,2,2,2,653,72,6.55,5.9,2,"cell organization and biogenesis","cytosol;endoplasmic reticulum;membrane","protein binding","Pf10267","23023","ENSG00000172765.16","TMCC1","3","","","",0,0,0.968,-0.05,0.849480060507206,0.999610319815025,89.8,103.3,106.8,"",12.78,9.11,108.4,"","",116.8,134.4,133.1,101.5,132.2,130.9,126.9,107.8,5.5,"","",93.2,101.7,105.7,73.5,95.2,130.9,103.4,86,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q96IQ9","Zinc finger protein 414 OS=Homo sapiens OX=9606 GN=ZNF414 PE=1 SV=2",0,7.998,9,2,2,2,312,32.8,7.81,5.78,2,"metabolic process;regulation of biological process","nucleus","DNA binding;metal ion binding;protein binding","","84330","ENSG00000133250.13","ZNF414","19","","","",0,0,0.949,-0.08,0.696907731745619,0.999610319815025,"",146.1,153.9,"",3.98,5.6,"","","",107.6,103.3,101.8,97.8,99.6,113.9,106.6,109.4,"","","",85.9,78.2,80.8,70.8,71.7,113.9,86.9,87.3,"Not Found","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q8TE67","Epidermal growth factor receptor kinase substrate 8-like protein 3 OS=Homo sapiens OX=9606 GN=EPS8L3 PE=1 SV=2",0,7.75,5,3,3,3,593,66.8,7.99,9.24,3,"regulation of biological process","cytoplasm","protein binding","Pf00018, Pf07653, Pf08239, Pf08416, Pf14604, Pf15502","79574","ENSG00000198758.10","EPS8L3","1","","","",0,0,1.035,0.05,0.693222429294098,0.999610319815025,"",152.6,147.4,"",8.15,3.75,"","","",55.9,55.9,65.6,62.5,56,60,55.3,58.3,"","","",44.6,42.3,52.1,45.3,40.3,60,45.1,46.5,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","O60927","E3 ubiquitin-protein ligase PPP1R11 OS=Homo sapiens OX=9606 GN=PPP1R11 PE=1 SV=1",0,7.282,21,2,3,2,126,13.9,7.01,5.52,2,"regulation of biological process","cytoplasm;nucleus","enzyme regulator activity;protein binding","Pf07491","6992","ENSG00000237829.6; ENSG00000227720.6; ENSG00000236560.6; ENSG00000233314.6; ENSG00000206501.8; ENSG00000237403.6; ENSG00000234058.6; ENSG00000204619.7","PPP1R11","6; CHR_HSCHR6_MHC_SSTO_CTG1; CHR_HSCHR6_MHC_DBB_CTG1; CHR_HSCHR6_MHC_MANN_CTG1; CHR_HSCHR6_MHC_APD_CTG1; CHR_HSCHR6_MHC_QBL_CTG1; CHR_HSCHR6_MHC_MCF_CTG1; CHR_HSCHR6_MHC_COX_CTG1","","","",0,0,1.017,0.02,0.821676464997971,0.999610319815025,98.8,101.4,99.7,"",6.43,3.94,205,"","",214.3,206.6,203.2,234,211.9,193.8,209.7,204.1,10.4,"","",171,156.4,161.4,169.5,152.6,193.8,170.9,162.9,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q8WVE0","EEF1A lysine methyltransferase 1 OS=Homo sapiens OX=9606 GN=EEF1AKMT1 PE=1 SV=1",0,6.943,9,2,2,2,214,24.5,4.55,6.21,2,"metabolic process","cytoplasm;cytosol","catalytic activity","Pf10237","221143","ENSG00000150456.10","N6AMT2; EEF1AKMT1","13","","Protein methylation","",3,0,0.979,-0.03,0.909429859327747,0.999610319815025,"",148.4,151.6,"",6.39,8.47,"","","",18.4,18.9,17.6,16.3,16.5,17.8,20.1,19,"","","",14.7,14.3,14,11.8,11.9,17.8,16.4,15.2,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q96IC2","RNA exonuclease 5 OS=Homo sapiens OX=9606 GN=REXO5 PE=2 SV=1",0,6.402,5,3,3,3,774,86.8,8.32,8.51,3,"metabolic process","","catalytic activity;RNA binding","Pf00076, Pf00929, Pf13893, Pf14259","81691","ENSG00000005189.19","LOC81691; REXO5","16","Ribosome biogenesis in eukaryotes","","",1,0,0.969,-0.05,0.831209682986628,0.999610319815025,120,88.6,91.4,"",7.11,5.6,86.7,"","",61.9,66.2,57.7,67.7,66.4,61.4,65.8,70.4,4.4,"","",49.4,50.1,45.8,49,47.8,61.4,53.6,56.2,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P78382","CMP-sialic acid transporter OS=Homo sapiens OX=9606 GN=SLC35A1 PE=1 SV=1",0,6.116,4,1,1,1,337,36.8,8.95,4.12,1,"metabolic process;transport","Golgi;membrane","transporter activity","Pf03151, Pf04142, Pf08449","10559","ENSG00000164414.17","SLC35A1","6","","Sialic acid metabolism; Defective SLC35A1 causes congenital disorder of glycosylation 2F (CDG2F); Defective SLC35A1 causes congenital disorder of glycosylation 2F (CDG2F); Transport of nucleotide sugars","",15,0,0.978,-0.03,0.841396747393338,0.999610319815025,104.4,96.7,98.9,"",9.43,4.67,301.6,"","",277.3,281.4,261.2,324.3,312.4,285.8,284,285.7,15.3,"","",221.3,213,207.4,234.9,225,285.8,231.5,228,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q9H5H4","Zinc finger protein 768 OS=Homo sapiens OX=9606 GN=ZNF768 PE=1 SV=2",0,5.832,6,3,3,3,540,60.2,7.97,9.63,3,"metabolic process;regulation of biological process","nucleus","DNA binding;metal ion binding;RNA binding","Pf00096, Pf07282, Pf13465, Pf14353","79724","ENSG00000169957.9","ZNF768","16","","","",0,0,0.94,-0.09,0.670442856163913,0.999610319815025,"",145.3,154.7,"",10.44,9.18,"","","",32.6,35.5,27.8,30.2,36.4,31.8,29.7,35.1,"","","",26,26.9,22.1,21.9,26.2,31.8,24.2,28,"Not Found","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q8NFZ5","TNFAIP3-interacting protein 2 OS=Homo sapiens OX=9606 GN=TNIP2 PE=1 SV=1",0,5.37,4,2,2,2,429,48.7,6.44,4.58,2,"cell death;defense response;metabolic process;regulation of biological process;response to stimulus","cytoplasm;cytosol;nucleus","metal ion binding;protein binding","Pf09731, Pf12180","79155","ENSG00000168884.14","TNIP2","4","","Ovarian tumor domain proteases; MAP3K8 (TPL2)-dependent MAPK1/3 activation; Activated TLR4 signalling; Interleukin-1 family signaling","Rac1/Pak1/p38/MMP-2 pathway",30,0,1.004,0.01,0.897134505103124,0.999610319815025,80.6,109.9,109.5,"",12.14,12.35,55.2,"","",63.4,79.7,71.2,83.7,77.2,79.7,59.6,72.8,2.8,"","",50.6,60.3,56.5,60.6,55.6,79.7,48.6,58.1,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q7L5N7","Lysophosphatidylcholine acyltransferase 2 OS=Homo sapiens OX=9606 GN=LPCAT2 PE=1 SV=1",1E-3,5.031,3,2,2,2,544,60.2,6.55,5.46,2,"cell organization and biogenesis;metabolic process","endoplasmic reticulum;Golgi;membrane","catalytic activity;metal ion binding","Pf00036, Pf01553, Pf04760, Pf13202, Pf13405, Pf13499, Pf13833","54947","ENSG00000087253.12","LPCAT2","16","Metabolic pathways; Ether lipid metabolism; Glycerophospholipid metabolism","Acyl chain remodelling of PC","",8,0,1.014,0.02,0.824506029301688,0.999610319815025,93.8,103.8,102.3,"",5.49,3.75,226.7,"","",250.9,250.6,253.9,225.1,235.5,241.5,254.7,253,11.5,"","",200.2,189.7,201.6,163,169.6,241.5,207.6,201.9,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q9ULX9","Transcription factor MafF OS=Homo sapiens OX=9606 GN=MAFF PE=1 SV=2",1E-3,4.635,14,2,2,1,164,17.7,9.8,2.31,2,"cell differentiation;coagulation;metabolic process;regulation of biological process","mitochondrion;nucleus","DNA binding","Pf03131","23764","ENSG00000185022.11","MAFF","22","","Factors involved in megakaryocyte development and platelet production","NRF2 pathway; Myometrial Relaxation and Contraction Pathways",4,0,0.98,-0.03,0.892643357422458,0.999610319815025,62.2,117.7,120.1,"",13.22,21.04,90.7,"","",165.7,149.6,177.4,204.2,160.2,191.1,153,239,4.6,"","",132.2,113.2,140.9,147.9,115.4,191.1,124.7,190.7,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q96MD2","KICSTOR complex protein C12orf66 OS=Homo sapiens OX=9606 GN=C12orf66 PE=1 SV=4",1E-3,4.351,4,2,2,2,445,50.4,8.91,5.07,2,"cell communication;response to stimulus","membrane;vacuole","","Pf09404","144577","","C12orf66","12","","","",0,0,1.029,0.04,0.741710168515454,0.999610319815025,104.1,99.3,96.5,"",4.7,11.17,57.2,"","",55.1,53.9,50.4,56.2,49.7,51.3,54.7,63.4,2.9,"","",44,40.8,40,40.7,35.8,51.3,44.6,50.6,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q9Y3E0","Vesicle transport protein GOT1B OS=Homo sapiens OX=9606 GN=GOLT1B PE=1 SV=1",1E-3,3.964,9,2,2,2,138,15.4,10.36,4.35,2,"regulation of biological process;response to stimulus;transport","endoplasmic reticulum;Golgi;membrane","signal transducer activity","Pf04178","51026","ENSG00000111711.9","GOLT1B","12","","","",0,0,1.042,0.06,0.67310628609473,0.999610319815025,91.3,106.5,102.2,"",7.31,5.72,364.6,"","",420.5,479.3,406.2,430.2,396.7,437.8,385.4,419.8,18.5,"","",335.6,362.8,322.6,311.6,285.7,437.8,314.1,335,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P14406","Cytochrome c oxidase subunit 7A2, mitochondrial OS=Homo sapiens OX=9606 GN=COX7A2 PE=1 SV=1",0.003,3.612,12,1,1,1,83,9.4,9.76,2.02,1,"metabolic process;transport","membrane;mitochondrion","catalytic activity;transporter activity","Pf02238","1347","","COX7A2","6","Alzheimer's disease; Oxidative phosphorylation; Non-alcoholic fatty liver disease (NAFLD); Huntington's disease; Cardiac muscle contraction; Parkinson's disease","","Electron Transport Chain",7,0,1.033,0.05,0.709254111983317,0.999610319815025,93.6,104.9,101.5,"",4.33,3.44,159.6,"","",180.2,193.2,175.7,177.7,172,174.5,165.4,179.7,8.1,"","",143.8,146.2,139.5,128.7,123.9,174.5,134.8,143.4,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P50443","Sulfate transporter OS=Homo sapiens OX=9606 GN=SLC26A2 PE=1 SV=2",0.003,3.296,1,1,1,1,739,81.6,8.38,3.7,1,"cellular homeostasis;metabolic process;transport","membrane","transporter activity","Pf00916, Pf01740, Pf13792","1836","ENSG00000155850.7","SLC26A2","5","","Defective SLC26A2 causes chondrodysplasias; Transport and synthesis of PAPS; Multifunctional anion exchangers","",17,0,1.02,0.03,0.760981959950963,0.999610319815025,76,113.1,110.9,"",10.27,8.06,69,"","",101.8,103.6,111.3,86.6,106.4,111.2,95.3,94.6,3.5,"","",81.2,78.4,88.4,62.7,76.6,111.2,77.7,75.5,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q96NU7","Probable imidazolonepropionase OS=Homo sapiens OX=9606 GN=AMDHD1 PE=1 SV=2",0.005,2.788,2,1,1,1,426,46.7,6.61,3.06,1,"metabolic process","cytoplasm;cytosol","catalytic activity;metal ion binding","Pf07969, Pf13147, Pf13594","144193","ENSG00000139344.7","AMDHD1","12","Histidine metabolism; Metabolic pathways","Histidine catabolism","",6,0,0.987,-0.02,0.958258983592591,0.999610319815025,"",149.1,150.9,"",9.92,12.29,"","","",28.8,24.4,22.9,25,22.6,23,27.2,28.9,"","","",23,18.5,18.2,18.1,16.3,23,22.2,23.1,"Not Found","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"Medium","Master Protein","Q969H0","F-box/WD repeat-containing protein 7 OS=Homo sapiens OX=9606 GN=FBXW7 PE=1 SV=1",0.012,2.267,2,1,1,1,707,79.6,5.8,2.85,1,"cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus","cytoplasm;cytosol;nucleus","catalytic activity;enzyme regulator activity;protein binding","Pf00400, Pf00646, Pf12937","55294","ENSG00000109670.13","FBXW7","4","Ubiquitin mediated proteolysis","Regulation of RUNX2 expression and activity; NOTCH1 Intracellular Domain Regulates Transcription; Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants; Antigen processing: Ubiquitination & Proteasome degradation; Neddylation; Association of TriC/CCT with target proteins during biosynthesis; Constitutive Signaling by NOTCH1 PEST Domain Mutants; Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling","Parkin-Ubiquitin Proteasomal System pathway; Pathways Affected in Adenoid Cystic Carcinoma; Notch Signaling Pathway",32,0,0.962,-0.06,0.814686546863529,0.999610319815025,"",147.1,152.9,"",7.85,8.95,"","","",41.6,38.6,46.3,44.2,40,43.9,49.7,45.2,"","","",33.2,29.2,36.8,32,28.8,43.9,40.5,36.1,"Not Found","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"Medium","Master Protein","Q9NQX1-3","Isoform 3 of PR domain zinc finger protein 5 OS=Homo sapiens OX=9606 GN=PRDM5",0.026,1.738,7,1,2,1,111,12.9,9.04,4.95,1,"cell organization and biogenesis;metabolic process;regulation of biological process","nucleus","catalytic activity;DNA binding;metal ion binding;protein binding","Pf00856","11107","ENSG00000138738.10","PRDM5","4","","","",0,0,1.016,0.02,0.822759985926037,0.999610319815025,101.4,100.1,98.5,"",6.05,2.1,778.5,"","",773.1,798.5,765.1,691.8,773.9,762.2,736.6,751.4,39.5,"","",616.9,604.4,607.6,501,557.4,762.2,600.3,599.6,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"Medium","Master Protein","Q6ZQQ6","WD repeat-containing protein 87 OS=Homo sapiens OX=9606 GN=WDR87 PE=1 SV=3",0.026,1.729,0,1,1,1,2873,333,7.28,2.64,1,"","","protein binding","Pf00400, Pf02463, Pf11600","83889","","WDR87","19","","","",0,0,0.966,-0.05,0.813547066943183,0.999610319815025,"",147.4,152.6,"",21.52,8.02,"","","",47.9,34.1,34.5,29.7,35.3,41,34.6,35.7,"","","",38.2,25.8,27.4,21.5,25.4,41,28.2,28.5,"Not Found","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"Low","Master Protein","Q8NFU1","Bestrophin-2 OS=Homo sapiens OX=9606 GN=BEST2 PE=2 SV=1",0.062,1.292,4,1,1,1,509,57.1,5.24,2.83,1,"transport","membrane","transporter activity","Pf01062","54831","ENSG00000039987.6","BEST2","19","Salivary secretion","Stimuli-sensing channels","",4,0,1.023,0.03,0.781271202246131,0.999610319815025,124.7,88.6,86.6,"",17.04,5.87,86.7,"","",80.1,54.7,59.7,63.7,56.1,63.2,62.7,57.9,4.4,"","",63.9,41.4,47.4,46.1,40.4,63.2,51.1,46.2,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q9BYG3","MKI67 FHA domain-interacting nucleolar phosphoprotein OS=Homo sapiens OX=9606 GN=NIFK PE=1 SV=1",0,80.597,46,15,20,15,293,34.2,9.88,63.52,15,"cell organization and biogenesis;metabolic process;regulation of biological process","chromosome;cytoplasm;nucleus","protein binding;RNA binding","Pf00076, Pf12196, Pf13893, Pf14259","84365","ENSG00000155438.11","MKI67IP; NIFK","2","","","",0,0,1.009,0.01,0.998611843129992,0.999972744932981,95.7,102.6,101.7,"",2.52,1.55,1768,"","",1925.2,1951.4,1867.7,1849.5,1873.4,1883.8,1863.9,1929.9,89.7,"","",1536.3,1477,1483.1,1339.5,1349.3,1883.8,1519.1,1540,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q92947","Glutaryl-CoA dehydrogenase, mitochondrial OS=Homo sapiens OX=9606 GN=GCDH PE=1 SV=1",0,68.941,34,11,17,11,438,48.1,8.06,60.31,11,"metabolic process","mitochondrion;organelle lumen","catalytic activity;nucleotide binding","Pf00441, Pf02770, Pf02771, Pf08028","2639","ENSG00000105607.12","GCDH","19","Tryptophan metabolism; Fatty acid degradation; Lysine degradation; Metabolic pathways","Lysine catabolism","Fatty Acid Beta Oxidation; Tryptophan metabolism",10,0,1.009,0.01,0.997728386489009,0.999972744932981,174.8,62.9,62.3,106.01,8.45,1.09,1894.1,13236.4,"",1824.6,1776.5,1866,1535.8,1775.3,1771.7,1814.2,1792.8,96.1,3.7,"",1456,1344.6,1481.8,1112.3,1278.6,1771.7,1478.6,1430.6,"High","High","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","O75879","Glutamyl-tRNA(Gln) amidotransferase subunit B, mitochondrial OS=Homo sapiens OX=9606 GN=GATB PE=1 SV=1",0,31.607,13,6,9,6,557,61.8,8.63,29.34,6,"cell organization and biogenesis;metabolic process","mitochondrion","catalytic activity;nucleotide binding;RNA binding","Pf02637, Pf02934","5188","ENSG00000059691.11","PET112; GATB","4","Metabolic pathways; Aminoacyl-tRNA biosynthesis","","",2,0,0.992,-0.01,0.99685696154546,0.999972744932981,98.4,100.4,101.2,"",11.94,9.64,244.4,"","",248.7,249.8,259.7,196.6,239.2,267,264.2,216.3,12.4,"","",198.5,189.1,206.2,142.4,172.3,267,215.3,172.6,"High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q13873","Bone morphogenetic protein receptor type-2 OS=Homo sapiens OX=9606 GN=BMPR2 PE=1 SV=2",0,7.434,3,2,2,2,1038,115.1,6.2,7.03,2,"cell communication;cell death;cell differentiation;cell proliferation;metabolic process;regulation of biological process;response to stimulus","cell surface;cytoplasm;membrane","catalytic activity;metal ion binding;nucleotide binding;protein binding;receptor activity;signal transducer activity","Pf00069, Pf01064, Pf01636, Pf07714","659","ENSG00000204217.13","BMPR2","2","Hippo signaling pathway; Signaling pathways regulating pluripotency of stem cells; MicroRNAs in cancer; Axon guidance; Cytokine-cytokine receptor interaction; TGF-beta signaling pathway","Signaling by BMP","Bone Morphogenic Protein (BMP) Signalling and Regulation; Heart Development; Mesodermal Commitment Pathway; Canonical and Non-Canonical TGF-B signaling; ESC Pluripotency Pathways",14,0,0.994,-0.01,0.997211049161712,0.999972744932981,"",149.5,150.5,"",4.79,22.67,"","","",28.7,27.3,30.1,30.4,35.5,35.3,24.8,22.9,"","","",22.9,20.7,23.9,22,25.6,35.3,20.2,18.3,"Not Found","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","O14974-3","Isoform 3 of Protein phosphatase 1 regulatory subunit 12A OS=Homo sapiens OX=9606 GN=PPP1R12A",0,155.227,33,36,46,1,974,109.7,5.35,139.89,36,"cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus","chromosome;cytoskeleton;cytosol","enzyme regulator activity;protein binding;signal transducer activity","Pf00023, Pf03961, Pf12796, Pf13606, Pf13637, Pf13857","4659","ENSG00000058272.16","PPP1R12A","12","","","Focal Adhesion; Regulation of Actin Cytoskeleton",2,0,"","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","Not Found","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","O95785-4","Isoform 4 of Protein Wiz OS=Homo sapiens OX=9606 GN=WIZ",0,90.404,33,19,23,1,835,89.3,9.48,62.47,19,"cell organization and biogenesis;regulation of biological process","nucleus","metal ion binding;protein binding","","58525","ENSG00000011451.17","WIZ","19","","","",0,0,"","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","Not Found","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q14114-3","Isoform 3 of Low-density lipoprotein receptor-related protein 8 OS=Homo sapiens OX=9606 GN=LRP8",0,45.726,15,12,14,1,904,99,5.03,38.65,12,"metabolic process;regulation of biological process;response to stimulus;transport","cell surface;extracellular;membrane","metal ion binding;protein binding;receptor activity;signal transducer activity","Pf00057, Pf00058, Pf06247, Pf07645, Pf08450, Pf12662, Pf14670","7804","ENSG00000157193.15","LRP8","1","","","",0,0,"","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P16383-3","Isoform 3 of GC-rich sequence DNA-binding factor 2 OS=Homo sapiens OX=9606 GN=GCFC2",0,29.372,32,5,7,1,215,23.6,5.35,23.19,5,"cell organization and biogenesis;metabolic process;regulation of biological process","cytosol;nucleus;spliceosomal complex","DNA binding;protein binding","","6936","ENSG00000005436.13","GCFC2","2","","","",0,0,"","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","Not Found","Not Found","Not Found","High","High","High","High","High","High","Not Found","High",1,""]
[false,"High","Master Protein","P06241","Tyrosine-protein kinase Fyn OS=Homo sapiens OX=9606 GN=FYN PE=1 SV=3",0,22.912,13,7,12,2,537,60.7,6.67,34.34,7,"cell differentiation;cell organization and biogenesis;cell proliferation;cellular component movement;coagulation;defense response;development;metabolic process;regulation of biological process;response to stimulus;transport","cytoplasm;cytosol;endosome;membrane;mitochondrion;nucleus","catalytic activity;metal ion binding;nucleotide binding;protein binding;signal transducer activity","Pf00017, Pf00018, Pf00069, Pf07653, Pf07714, Pf14604","2534","ENSG00000010810.17","FYN","6","T cell receptor signaling pathway; Axon guidance; Adherens junction; Pathogenic Escherichia coli infection; Platelet activation; Fc epsilon RI signaling pathway; Natural killer cell mediated cytotoxicity; Osteoclast differentiation; Sphingolipid signaling pathway; Focal adhesion; Cholinergic synapse; Phospholipase D signaling pathway; Viral myocarditis; Prion diseases; Measles","SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion; Sema3A PAK dependent Axon repulsion; PECAM1 interactions; CRMPs in Sema3A signaling; CTLA4 inhibitory signaling; Interleukin-7 signaling; NCAM signaling for neurite out-growth; Nef and signal transduction; EPH-ephrin mediated repulsion of cells; Nephrin family interactions; Ephrin signaling; EPHA-mediated growth cone collapse; DAP12 signaling; EPHB-mediated forward signaling; Reelin signalling pathway; Regulation of signaling by CBL; FCGR activation; Constitutive Signaling by Aberrant PI3K in Cancer; Antigen activates B Cell Receptor (BCR) leading to generation of second messengers; Interleukin-20 family signaling; DCC mediated attractive signaling; Netrin mediated repulsion signals; PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling; Dectin-2 family; VEGFA-VEGFR2 Pathway; Platelet Adhesion to exposed collagen; CD209 (DC-SIGN) signaling; CD28 dependent Vav1 pathway; GPVI-mediated activation cascade; CD28 dependent PI3K/Akt signaling; Regulation of KIT signaling; Role of LAT2/NTAL/LAB on calcium mobilization; Signaling by ERBB2; RAF/MAP kinase cascade","Integrin-mediated Cell Adhesion; Leptin signaling pathway; Prolactin Signaling Pathway; IL-7 Signaling Pathway; Pathogenic Escherichia coli infection; B Cell Receptor Signaling Pathway; Interleukin-11 Signaling Pathway; Brain-Derived Neurotrophic Factor (BDNF) signaling pathway; Primary Focal Segmental Glomerulosclerosis FSGS; T-Cell Receptor and Co-stimulatory Signaling; Ectoderm Differentiation; IL-3 Signaling Pathway; Kit receptor signaling pathway; Focal Adhesion; T-Cell antigen Receptor (TCR) pathway during Staphylococcus aureus infection; VEGFA-VEGFR2 Signaling Pathway; IL-2 Signaling Pathway; Interferon type I signaling pathways; T-Cell antigen Receptor (TCR)  Signaling Pathway",106,0,"","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","Not Found","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q15011","Homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 1 protein OS=Homo sapiens OX=9606 GN=HERPUD1 PE=1 SV=1",0,17.568,9,5,5,5,391,43.7,5.25,14.58,5,"cellular homeostasis;metabolic process;regulation of biological process;response to stimulus;transport","endoplasmic reticulum;membrane","protein binding","Pf00240","9709","ENSG00000051108.14","HERPUD1","16","Protein processing in endoplasmic reticulum","ATF4 activates genes","VEGFA-VEGFR2 Signaling Pathway; Exercise-induced Circadian Regulation",7,0,"","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q9P243","Zinc finger protein ZFAT OS=Homo sapiens OX=9606 GN=ZFAT PE=1 SV=2",0,14.727,4,4,4,4,1243,138.9,7.25,10.83,4,"cell differentiation;metabolic process;regulation of biological process","cytoplasm;cytosol;nucleus","DNA binding;metal ion binding","Pf13465","57623","ENSG00000066827.15","ZFAT","8","","","",0,0,"","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P51957-2","Isoform 2 of Serine/threonine-protein kinase Nek4 OS=Homo sapiens OX=9606 GN=NEK4",0,12.928,5,3,3,1,781,88,7.77,9.41,3,"cell division;metabolic process;regulation of biological process;response to stimulus","cytoplasm","catalytic activity;metal ion binding;nucleotide binding","Pf00069, Pf07714","6787","ENSG00000114904.12","NEK4","3","","","",0,0,"","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","Not Found","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","O95848","Uridine diphosphate glucose pyrophosphatase NUDT14 OS=Homo sapiens OX=9606 GN=NUDT14 PE=1 SV=2",0,11.64,19,3,3,3,222,24.1,5.05,7.56,3,"metabolic process","cytoplasm;cytosol","catalytic activity;metal ion binding;protein binding","Pf00293","256281","ENSG00000183828.14","NUDT14","14","","Synthesis of dolichyl-phosphate-glucose","",6,0,"","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q14410","Glycerol kinase 2 OS=Homo sapiens OX=9606 GN=GK2 PE=2 SV=2",0,10.445,5,2,3,1,553,60.6,5.77,9.85,2,"metabolic process","cytoplasm;membrane;mitochondrion","catalytic activity;nucleotide binding","Pf00370, Pf02782","2712","ENSG00000196475.5","GK2","4","PPAR signaling pathway; Metabolic pathways; Glycerolipid metabolism","Triglyceride biosynthesis","Fatty Acid Beta Oxidation; Triacylglyceride Synthesis; PPAR signaling pathway",10,0,"","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","Not Found","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q96N06","Spermatogenesis-associated protein 33 OS=Homo sapiens OX=9606 GN=SPATA33 PE=2 SV=1",0,9.427,13,1,1,1,139,15.5,9.22,4.24,1,"","cytoplasm;cytosol;nucleus","","Pf15382","124045","ENSG00000167523.13","C16orf55; SPATA33","16","","","",0,0,"","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q92831","Histone acetyltransferase KAT2B OS=Homo sapiens OX=9606 GN=KAT2B PE=1 SV=3",0,8.607,4,3,3,2,832,93,9.01,8.57,3,"cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus","chromosome;nucleus","catalytic activity;DNA binding;enzyme regulator activity;protein binding","Pf00439, Pf00583, Pf06466, Pf13508","8850","ENSG00000114166.7","KAT2B","3","Viral carcinogenesis; Notch signaling pathway; Thyroid hormone signaling pathway; HTLV-I infection","NOTCH1 Intracellular Domain Regulates Transcription; RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function; HATs acetylate histones; Notch-HLH transcription pathway; Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants; Physiological factors; YAP1- and WWTR1 (TAZ)-stimulated gene expression; Constitutive Signaling by NOTCH1 PEST Domain Mutants; RUNX3 regulates NOTCH signaling; Pre-NOTCH Transcription and Translation; B-WICH complex positively regulates rRNA expression; RNA Polymerase I Transcription Initiation; Metalloprotease DUBs","Androgen receptor signaling pathway; Notch Signaling Pathway",44,0,"","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P49810","Presenilin-2 OS=Homo sapiens OX=9606 GN=PSEN2 PE=1 SV=1",0,8.083,6,2,2,2,448,50.1,4.59,6.08,2,"metabolic process;regulation of biological process;response to stimulus;transport","cell surface;chromosome;endoplasmic reticulum;Golgi;membrane","catalytic activity;protein binding","Pf01080","5664","ENSG00000143801.16","PSEN2","1","Alzheimer's disease; Notch signaling pathway; Neurotrophin signaling pathway","Activated NOTCH1 Transmits Signal to the Nucleus; Signaling by NOTCH4; Regulated proteolysis of p75NTR; Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants; NRIF signals cell death from the nucleus; Signaling by NOTCH3; EPH-ephrin mediated repulsion of cells; NOTCH2 Activation and Transmission of Signal to the Nucleus; Constitutive Signaling by NOTCH1 PEST Domain Mutants; Nuclear signaling by ERBB4; Signalling by NGF","Alzheimers Disease; Notch Signaling Pathway; Canonical  and Non-canonical Notch signaling; Notch Signaling Pathway",34,0,"","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","High","High","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q96F05","Uncharacterized protein C11orf24 OS=Homo sapiens OX=9606 GN=C11orf24 PE=1 SV=2",0,7.674,6,1,1,1,449,46.1,5.87,5.59,1,"","Golgi;membrane","","Pf15316","53838","ENSG00000171067.10","C11orf24","11","","","",0,0,"","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","Not Found","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","O76076","WNT1-inducible-signaling pathway protein 2 OS=Homo sapiens OX=9606 GN=WISP2 PE=1 SV=1",0,7.157,11,1,2,1,250,26.8,7.88,6.98,1,"cell communication;regulation of biological process;response to stimulus","extracellular","protein binding","Pf00093","8839","ENSG00000064205.10","WISP2","20","","","",0,0,"","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","Not Found","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q8N8K9-2","Isoform 2 of Uncharacterized protein KIAA1958 OS=Homo sapiens OX=9606 GN=KIAA1958",0,6.744,3,1,1,1,738,81.6,6.64,5.48,1,"regulation of biological process","cytoplasm","DNA binding;protein binding","Pf12012","158405","ENSG00000165185.14","KIAA1958","9","","","",0,0,"","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","Not Found","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q02413","Desmoglein-1 OS=Homo sapiens OX=9606 GN=DSG1 PE=1 SV=2",0,6.479,1,1,1,1,1049,113.7,5.03,4.78,1,"cell death;cell organization and biogenesis;regulation of biological process;response to stimulus;transport","cytoskeleton;cytosol;membrane","metal ion binding;protein binding","Pf00028, Pf01049","1828","ENSG00000134760.5","DSG1","18","Staphylococcus aureus infection","Apoptotic cleavage of cell adhesion  proteins; Formation of the cornified envelope; Neutrophil degranulation","",12,0,"","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q8IWZ6","Bardet-Biedl syndrome 7 protein OS=Homo sapiens OX=9606 GN=BBS7 PE=1 SV=2",0,6.178,2,1,1,1,715,80.3,6.05,3.83,1,"cell differentiation;cell organization and biogenesis;regulation of biological process;response to stimulus;transport","cytoplasm;cytoskeleton;cytosol;membrane;nucleus","protein binding","Pf14783","55212","ENSG00000138686.9","BBS7","4","","BBSome-mediated cargo-targeting to cilium","",4,0,"","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","Not Found","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q8IZ52","Chondroitin sulfate synthase 2 OS=Homo sapiens OX=9606 GN=CHPF PE=1 SV=2",0,5.892,3,2,2,2,775,85.4,6.93,5.59,2,"metabolic process","cytoplasm;cytosol;Golgi;membrane;mitochondrion;organelle lumen","catalytic activity;metal ion binding;protein binding","Pf02434, Pf05679","79586","ENSG00000123989.13","CHPF","2","Metabolic pathways; Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate","Chondroitin sulfate biosynthesis","",7,0,"","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q16842","CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 2 OS=Homo sapiens OX=9606 GN=ST3GAL2 PE=2 SV=1",0,5.632,8,2,2,2,350,40.1,8.35,5.13,2,"metabolic process","extracellular;Golgi;membrane","catalytic activity","Pf00777","6483","ENSG00000157350.12","ST3GAL2","16","Metabolic pathways; Glycosaminoglycan biosynthesis - keratan sulfate; Mucin type O-glycan biosynthesis; Glycosphingolipid biosynthesis - globo and isoglobo series; Glycosphingolipid biosynthesis - ganglio series","Keratan sulfate biosynthesis; Termination of O-glycan biosynthesis; Sialic acid metabolism","Ganglio Sphingolipid Metabolism; Globo Sphingolipid Metabolism",21,0,"","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","Not Found","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q86UD1","Out at first protein homolog OS=Homo sapiens OX=9606 GN=OAF PE=2 SV=1",0,5.517,3,1,2,1,273,30.7,6.84,4.97,1,"","","","Pf14941","220323","ENSG00000184232.8","OAF","11","","","",0,0,"","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","Not Found","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q9NXL9","DNA helicase MCM9 OS=Homo sapiens OX=9606 GN=MCM9 PE=1 SV=4",1E-3,5.282,1,1,1,1,1143,127.2,7.74,4.34,1,"metabolic process;response to stimulus","nucleus","catalytic activity;DNA binding;nucleotide binding","Pf00493, Pf07728, Pf14551","254394","ENSG00000111877.17","MCM9","6","","","Cell Cycle",1,0,"","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","Not Found","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P50458","LIM/homeobox protein Lhx2 OS=Homo sapiens OX=9606 GN=LHX2 PE=2 SV=2",1E-3,5.028,6,1,1,1,406,44.3,8.48,2.87,1,"cell differentiation;cell growth;cellular component movement;metabolic process;regulation of biological process","nucleus","DNA binding;metal ion binding","Pf00046, Pf00412, Pf05920","9355","ENSG00000106689.10","LHX2","9","","Regulation of expression of SLITs and ROBOs","Neural Crest Differentiation",5,0,"","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","Not Found","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P48380","Transcription factor RFX3 OS=Homo sapiens OX=9606 GN=RFX3 PE=1 SV=2",1E-3,4.817,5,2,2,2,749,83.5,6,4.62,2,"cell differentiation;cell organization and biogenesis;cellular component movement;development;metabolic process;regulation of biological process","nucleus","DNA binding;protein binding","Pf02257, Pf04589","5991","ENSG00000080298.15","RFX3","9","","","",0,0,"","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q9H015","Solute carrier family 22 member 4 OS=Homo sapiens OX=9606 GN=SLC22A4 PE=1 SV=3",1E-3,4.619,2,1,1,1,551,62.1,7.23,3.87,1,"metabolic process;transport","membrane;mitochondrion","nucleotide binding;protein binding;transporter activity","Pf00083, Pf07690, Pf13347","6583","ENSG00000197208.5","SLC22A4","5","Choline metabolism in cancer","Organic cation transport","",6,0,"","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","Not Found","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q86VK4","Zinc finger protein 410 OS=Homo sapiens OX=9606 GN=ZNF410 PE=1 SV=2",1E-3,4.415,4,2,2,2,478,52.1,6.29,5.85,2,"metabolic process;regulation of biological process","nucleus","DNA binding;metal ion binding;protein binding","Pf00096, Pf13465, Pf13894","57862","ENSG00000119725.18","ZNF410","14","","","",0,0,"","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q9NQ89","Protein C12orf4 OS=Homo sapiens OX=9606 GN=C12orf4 PE=1 SV=1",1E-3,4.234,3,1,1,1,552,63.8,6.37,2.47,1,"regulation of biological process","cytoplasm","","Pf10154","57102","ENSG00000047621.11","C12orf4","12","","","",0,0,"","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q32ZE0","Genome polyprotein OS=Bussuquara virus OX=64304 PE=3 SV=1",1E-3,4.039,1,2,2,2,3429,378.9,8.56,4.82,2,"cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus;transport","extracellular;membrane","catalytic activity;metal ion binding;nucleotide binding;protein binding;RNA binding;structural molecule activity","Pf00270, Pf00271, Pf00869, Pf00948, Pf00949, Pf00972, Pf01002, Pf01003, Pf01004, Pf01005, Pf01349, Pf01350, Pf01570, Pf01728, Pf02832, Pf07652, Pf13245","5075867","","BSQV_gp1; flavivirus polyprotein gene","","","","",0,0,"","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q96AP7","Endothelial cell-selective adhesion molecule OS=Homo sapiens OX=9606 GN=ESAM PE=1 SV=1",1E-3,3.889,3,1,1,1,390,41.2,9.32,2.44,1,"cellular component movement","membrane","protein binding","Pf00047, Pf07679, Pf13895, Pf13927","90952","ENSG00000149564.11","ESAM","11","Leukocyte transendothelial migration; Cell adhesion molecules (CAMs)","Cell surface interactions at the vascular wall","",4,0,"","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","Not Found","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q96NU1","Sterile alpha motif domain-containing protein 11 OS=Homo sapiens OX=9606 GN=SAMD11 PE=1 SV=3",0.003,3.748,2,1,1,1,681,72.7,7.59,3.15,1,"","nucleus","protein binding","Pf07647","148398","ENSG00000187634.11","SAMD11","1","","","",0,0,"","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","Not Found","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q96LW9","Zinc finger and SCAN domain-containing protein 31 OS=Homo sapiens OX=9606 GN=ZSCAN31 PE=1 SV=2",0.003,3.59,3,1,2,1,406,47.3,6.89,5.2,1,"metabolic process;regulation of biological process","nucleus","DNA binding;metal ion binding","Pf00096, Pf02023, Pf13465","64288","ENSG00000235109.7","ZNF323; ZSCAN31","6","","","",0,0,"","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","Not Found","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q9Y255","PRELI domain-containing protein 1, mitochondrial OS=Homo sapiens OX=9606 GN=PRELID1 PE=1 SV=1",0.003,3.457,7,2,2,2,219,25.2,9.54,4.1,2,"cell death;cell organization and biogenesis;development;regulation of biological process;response to stimulus;transport","mitochondrion","protein binding;transporter activity","Pf04707","27166","ENSG00000169230.9","PRELID1","5","","TP53 Regulates Transcription of Genes Involved in Cytochrome C Release","",6,0,"","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q15973","Zinc finger protein 124 OS=Homo sapiens OX=9606 GN=ZNF124 PE=1 SV=2",0.003,3.335,5,1,1,1,351,40.2,8.82,3.02,1,"metabolic process;regulation of biological process","nucleus","DNA binding;metal ion binding;protein binding","Pf00096, Pf01352, Pf13465","7678","ENSG00000196418.12","ZNF124","1","","Generic Transcription Pathway","",3,0,"","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","Not Found","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q6UXY8","Transmembrane channel-like protein 5 OS=Homo sapiens OX=9606 GN=TMC5 PE=2 SV=3",0.004,3.226,1,1,1,1,1006,114.7,8.21,3.09,1,"transport","membrane","transporter activity","Pf07810","79838","ENSG00000103534.16","TMC5","16","","","",0,0,"","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","Not Found","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q15742","NGFI-A-binding protein 2 OS=Homo sapiens OX=9606 GN=NAB2 PE=1 SV=1",0.004,3.04,2,1,1,1,525,56.6,6.96,2.67,1,"cell differentiation;cell proliferation;metabolic process;regulation of biological process","nucleus","protein binding","Pf04904, Pf04905","4665","ENSG00000166886.12","NAB2","12","","","",0,0,"","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","High","Not Found","High","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q8NFJ9","Bardet-Biedl syndrome 1 protein OS=Homo sapiens OX=9606 GN=BBS1 PE=1 SV=1",0.005,2.906,2,1,1,1,593,65,7.93,2.71,1,"cell organization and biogenesis;response to stimulus;transport","cytoplasm;cytoskeleton;cytosol;membrane","protein binding","Pf14779","582","ENSG00000174483.19","BBS1","11","","BBSome-mediated cargo-targeting to cilium","",4,0,"","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q6PII3","Coiled-coil domain-containing protein 174 OS=Homo sapiens OX=9606 GN=CCDC174 PE=1 SV=3",0.005,2.782,2,1,1,1,467,53.9,6.33,2.58,1,"","nucleus","protein binding","Pf13300","51244","ENSG00000154781.15","CCDC174","3","","","",0,0,"","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","Not Found","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","P11309","Serine/threonine-protein kinase pim-1 OS=Homo sapiens OX=9606 GN=PIM1 PE=1 SV=4",0.007,2.646,3,1,1,1,313,35.7,6.11,3.21,1,"cell communication;cell death;cell proliferation;development;metabolic process;regulation of biological process;response to stimulus","cytoplasm;cytosol;membrane;nucleus","catalytic activity;metal ion binding;nucleotide binding;protein binding","Pf00069, Pf06293, Pf07714, Pf14531","5292","ENSG00000137193.13","PIM1","6","","","Ectoderm Differentiation; Imatinib and Chronic Myeloid Leukemia",2,0,"","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","Not Found","Not Found","Not Found","Not Found","Not Found","Not Found","Not Found","Not Found","Not Found","Not Found","Not Found",1,""]
[false,"High","Master Protein","O94952-1","Isoform 2 of F-box only protein 21 OS=Homo sapiens OX=9606 GN=FBXO21",0.008,2.561,1,1,1,1,621,71.4,6.01,2.28,1,"metabolic process","cytosol","catalytic activity;DNA binding;protein binding","Pf00646, Pf08755, Pf12937, Pf13369","23014","ENSG00000135108.14","FBXO21","12","","","",0,0,"","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","Not Found","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"High","Master Protein","Q9H1C7","Cysteine-rich and transmembrane domain-containing protein 1 OS=Homo sapiens OX=9606 GN=CYSTM1 PE=1 SV=1",0.008,2.561,11,1,1,1,97,10.6,4.32,3.03,1,"transport","membrane","","","84418","ENSG00000120306.9","CYSTM1","5","","Neutrophil degranulation","",3,0,"","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"Medium","Master Protein","Q4KMG0","Cell adhesion molecule-related/down-regulated by oncogenes OS=Homo sapiens OX=9606 GN=CDON PE=1 SV=2",0.01,2.439,1,1,1,1,1287,139.1,6.51,2.92,1,"cell differentiation;regulation of biological process;response to stimulus","membrane","protein binding","Pf00041, Pf00047, Pf07654, Pf07679, Pf13895, Pf13927","50937","ENSG00000064309.14","CDON","11","Hedgehog signaling pathway","Ligand-receptor interactions; CDO in myogenesis; Activation of SMO","Ectoderm Differentiation; Mecp2 and Associated Rett Syndrome",11,0,"","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","Not Found","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"Medium","Master Protein","Q6NVV7","Cysteine-rich DPF motif domain-containing protein 1 OS=Homo sapiens OX=9606 GN=CDPF1 PE=1 SV=1",0.012,2.292,9,1,1,1,123,13.9,8,2.98,1,"","","protein binding","Pf10170","150383","ENSG00000205643.10","CDPF1","22","","","",0,0,"","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"Medium","Master Protein","Q6PEV8","Protein FAM199X OS=Homo sapiens OX=9606 GN=FAM199X PE=1 SV=1",0.014,2.173,4,1,1,1,388,42.8,5.08,0,1,"","","protein binding","","139231","ENSG00000123575.8","FAM199X","X","","","",0,0,"","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"Medium","Master Protein","Q9UPU3","VPS10 domain-containing receptor SorCS3 OS=Homo sapiens OX=9606 GN=SORCS3 PE=2 SV=2",0.015,2.082,2,1,1,1,1222,135.7,6.6,3,1,"regulation of biological process;response to stimulus","membrane","protein binding;receptor activity;signal transducer activity","Pf00801","22986","ENSG00000156395.12","SORCS3","10","","","",0,0,"","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","Not Found","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"Medium","Master Protein","Q2NKX9","UPF0561 protein C2orf68 OS=Homo sapiens OX=9606 GN=C2orf68 PE=2 SV=1",0.016,1.996,6,1,1,1,166,18.7,8.31,2.39,1,"","","","Pf10573","388969","ENSG00000168887.10","C2orf68","2","","","",0,0,"","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"Medium","Master Protein","Q68EA5","Zinc finger protein 57 OS=Homo sapiens OX=9606 GN=ZNF57 PE=2 SV=3",0.019,1.916,2,1,1,1,555,64.4,8.76,2.69,1,"metabolic process;regulation of biological process","nucleus","DNA binding;metal ion binding","Pf01352, Pf13465","126295","ENSG00000171970.12","ZNF57","19","","","",0,0,"","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","Not Found","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"Medium","Master Protein","Q9Y343","Sorting nexin-24 OS=Homo sapiens OX=9606 GN=SNX24 PE=1 SV=1",0.022,1.843,5,1,1,1,169,19.8,7.24,2.22,1,"transport","membrane","","Pf00787","28966","ENSG00000064652.10","SNX24","5","","","",0,0,"","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"Medium","Master Protein","Q5IS51","Neuronal acetylcholine receptor subunit alpha-5 OS=Pan troglodytes OX=9598 GN=CHRNA5 PE=2 SV=1",0.025,1.769,2,1,2,1,468,53,6.98,4.43,1,"cell communication;response to stimulus;transport","membrane","transporter activity","Pf02931, Pf02932","619369","","CHRNA5","15","Neuroactive ligand-receptor interaction","","",1,0,"","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"Medium","Master Protein","Q14183-2","Isoform 2 of Double C2-like domain-containing protein alpha OS=Homo sapiens OX=9606 GN=DOC2A",0.029,1.695,7,1,1,1,163,18.4,8.57,2.52,1,"cell communication;cell organization and biogenesis;regulation of biological process;transport","membrane;nucleus;vacuole","metal ion binding;protein binding","Pf00168","8448","ENSG00000149927.17","DOC2A","16","","","",0,0,"","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"Medium","Master Protein","Q6ZNQ3-2","Isoform 2 of Leucine-rich repeat-containing protein 69 OS=Homo sapiens OX=9606 GN=LRRC69",0.035,1.626,8,1,1,1,191,21.8,9.03,2.42,1,"","","","","100130742","ENSG00000214954.8","LRRC69","8","","","",0,0,"","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","Not Found","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"Medium","Master Protein","Q6UWP8","Suprabasin OS=Homo sapiens OX=9606 GN=SBSN PE=1 SV=2",0.039,1.583,9,1,1,1,590,60.5,7.01,0,1,"","extracellular","","","374897","ENSG00000189001.10","SBSN","19","","","",0,0,"","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","Not Found","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"Medium","Master Protein","Q6P5X5","UPF0545 protein C22orf39 OS=Homo sapiens OX=9606 GN=C22orf39 PE=1 SV=2",0.042,1.555,9,1,1,1,142,16.8,8,2.34,1,"","","protein binding","","128977","ENSG00000242259.8","C22orf39","22","","","",0,0,"","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","Not Found","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"Medium","Master Protein","Q969Z4","Tumor necrosis factor receptor superfamily member 19L OS=Homo sapiens OX=9606 GN=RELT PE=1 SV=1",0.044,1.511,4,1,1,1,430,46.1,8.35,0,1,"defense response;development;regulation of biological process;response to stimulus","cytoplasm;membrane","receptor activity;signal transducer activity","Pf12606","84957","ENSG00000054967.12","RELT","11","Cytokine-cytokine receptor interaction","","",1,0,"","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","Not Found","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"Medium","Master Protein","Q8IWA6","Coiled-coil domain-containing protein 60 OS=Homo sapiens OX=9606 GN=CCDC60 PE=1 SV=2",0.048,1.449,2,1,1,1,550,63.1,9.69,2.49,1,"","","protein binding","","160777","ENSG00000183273.6","CCDC60","12","","","",0,0,"","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"Low","Master Protein","Q8TC57","Meiosis 1 arrest protein OS=Homo sapiens OX=9606 GN=M1AP PE=1 SV=1",0.053,1.394,2,1,1,1,530,59.3,6.87,0,1,"cell differentiation;cell organization and biogenesis;metabolic process","cytoplasm","protein binding","","130951","ENSG00000159374.17","C2orf65; M1AP","2","","","",0,0,"","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","Not Found","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"Low","Master Protein","Q8IYF1","Elongin-A2 OS=Homo sapiens OX=9606 GN=ELOA2 PE=1 SV=2",0.057,1.359,2,1,1,1,753,83.9,9.73,2.43,1,"metabolic process;regulation of biological process","nucleus","DNA binding;protein binding","Pf06881, Pf08711","51224","ENSG00000206181.5","TCEB3B; ELOA2","18","","HIV elongation arrest and recovery; TP53 Regulates Transcription of DNA Repair Genes; Tat-mediated HIV elongation arrest and recovery; Formation of RNA Pol II elongation complex ; Formation of HIV elongation complex in the absence of HIV Tat; RNA Polymerase II Pre-transcription Events; Pausing and recovery of HIV elongation; Pausing and recovery of Tat-mediated HIV elongation; Formation of HIV-1 elongation complex containing HIV-1 Tat","",22,0,"","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","Not Found","Not Found","Not Found","High","High","High","High","High","High","High","Not Found",1,""]
[false,"Low","Master Protein","Q9Y4L5","E3 ubiquitin-protein ligase RNF115 OS=Homo sapiens OX=9606 GN=RNF115 PE=1 SV=2",0.06,1.311,3,1,1,1,304,33.7,5.69,2.28,1,"metabolic process;regulation of biological process","cytoplasm;cytosol","catalytic activity;metal ion binding;protein binding","Pf00097, Pf12678, Pf13639, Pf13920, Pf13923, Pf14369, Pf14634","27246","ENSG00000265491.4","RNF115; LOC101060478","1","","Antigen processing: Ubiquitination & Proteasome degradation","",4,0,"","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","Not Found","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"Low","Master Protein","Q9HC29","Nucleotide-binding oligomerization domain-containing protein 2 OS=Homo sapiens OX=9606 GN=NOD2 PE=1 SV=1",0.063,1.274,1,1,1,1,1040,115.2,6.76,1.76,1,"cell organization and biogenesis;defense response;metabolic process;regulation of biological process;response to stimulus;transport","cell surface;cytoplasm;cytoskeleton;cytosol;Golgi;membrane","nucleotide binding;protein binding","Pf00619, Pf05729","64127","ENSG00000167207.11","NOD2","16","TNF signaling pathway; Tuberculosis; Shigellosis; NOD-like receptor signaling pathway; Inflammatory bowel disease (IBD)","NOD1/2 Signaling Pathway; Ovarian tumor domain proteases; TAK1 activates NFkB by phosphorylation and activation of IKKs complex; Activated TLR4 signalling; Interleukin-1 family signaling; JNK (c-Jun kinases) phosphorylation and  activation mediated by activated human TAK1; activated TAK1 mediates p38 MAPK activation","Nucleotide-binding Oligomerization Domain (NOD) pathway",39,0,"","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","Not Found","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"Low","Master Protein","P36743","Major capsid protein L1 OS=Human papillomavirus type 56 OX=10596 GN=L1 PE=3 SV=1",0.067,1.24,2,1,1,1,534,60.1,8.35,2.15,1,"transport","","structural molecule activity","Pf00500","","","","","","","",0,0,"","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"Low","Master Protein","P0C1S8","Wee1-like protein kinase 2 OS=Homo sapiens OX=9606 GN=WEE2 PE=1 SV=2",0.069,1.221,2,1,1,1,567,62.9,6.51,0,1,"cell organization and biogenesis;metabolic process;regulation of biological process","cytoplasm;cytosol;nucleus","catalytic activity;metal ion binding;nucleotide binding","Pf00069, Pf07714","494551","ENSG00000214102.7; ENSG00000263042.5","WEE2","7; CHR_HSCHR7_1_CTG6","Cell cycle","","",1,0,"","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"Low","Master Protein","A7J3A4","Protein VP3 OS=Rotavirus A (strain RVA/Human/Japan/YO/1977/G3P1A[8]) OX=578832 PE=3 SV=1",0.069,1.22,1,1,1,1,835,98,8.73,2.51,1,"metabolic process","","catalytic activity;nucleotide binding;RNA binding","Pf05213, Pf06929","","","","","","","",0,0,"","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"Low","Master Protein","Q8QZ72","Structural polyprotein OS=Mayaro virus (strain Brazil) OX=374990 PE=3 SV=1",0.069,1.219,1,1,1,1,1242,137,8.66,2.93,1,"cell organization and biogenesis;metabolic process","membrane","catalytic activity;protein binding;structural molecule activity","Pf00943, Pf00944, Pf01563, Pf01589","935141","","MAYVgp3","","","","",0,0,"","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"Low","Master Protein","Q9H6L5","Reticulophagy regulator 1 OS=Homo sapiens OX=9606 GN=RETREG1 PE=1 SV=1",0.069,1.219,3,1,1,1,497,54.6,4.63,2.48,1,"metabolic process;regulation of biological process","endoplasmic reticulum;Golgi;membrane","protein binding","","54463","ENSG00000154153.13","FAM134B; RETREG1","5","","","",0,0,"","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"Low","Master Protein","P28698","Myeloid zinc finger 1 OS=Homo sapiens OX=9606 GN=MZF1 PE=1 SV=3",0.07,1.218,1,1,1,1,734,82,8.19,1.62,1,"metabolic process;regulation of biological process","nucleus","DNA binding;metal ion binding;protein binding","Pf00096, Pf02023, Pf13465","7593","ENSG00000099326.8","MZF1","19","","","Ectoderm Differentiation",1,0,"","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"Low","Master Protein","P0C704","Major capsid protein OS=Epstein-Barr virus (strain GD1) OX=10376 GN=MCP PE=3 SV=1",0.07,1.217,1,1,1,1,1381,153.8,6.55,0,1,"","","structural molecule activity","Pf03122","5176226","","HHV4tp2_gp58","","","","",0,0,"","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"Low","Master Protein","P57727","Transmembrane protease serine 3 OS=Homo sapiens OX=9606 GN=TMPRSS3 PE=1 SV=2",0.07,1.217,2,1,1,1,454,49.4,6.4,2.08,1,"cellular homeostasis;metabolic process;transport","endoplasmic reticulum;membrane","catalytic activity;protein binding;receptor activity","Pf00057, Pf00089, Pf00530, Pf09272, Pf09342, Pf15494","64699","ENSG00000160183.13","TMPRSS3","21","","","",0,0,"","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"Low","Master Protein","Q7Z698","Sprouty-related, EVH1 domain-containing protein 2 OS=Homo sapiens OX=9606 GN=SPRED2 PE=1 SV=2",0.071,1.215,3,1,1,1,418,47.5,6.79,1.67,1,"development;regulation of biological process;response to stimulus","cytoplasm;cytosol;membrane","enzyme regulator activity;protein binding","Pf00568, Pf05210","200734","ENSG00000198369.9","SPRED2","2","","Regulation of RAS by GAPs; FGFRL1 modulation of FGFR1 signaling; Signaling by RAS mutants; Interleukin-20 family signaling","Imatinib and Chronic Myeloid Leukemia",18,0,"","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","Not Found","Not Found","Not Found","Not Found","Not Found","Not Found","Not Found","Not Found","Not Found","Not Found","Not Found",1,""]
[false,"Low","Master Protein","Q9BPZ3","Polyadenylate-binding protein-interacting protein 2 OS=Homo sapiens OX=9606 GN=PAIP2 PE=1 SV=1",0.07,1.212,6,1,1,1,127,15,4.12,2.19,1,"regulation of biological process;response to stimulus","cytoplasm","protein binding;RNA binding;translation regulator activity","Pf07145","51247","ENSG00000120727.12","PAIP2","5","","","",0,0,"","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"Low","Master Protein","Q9NS39","Double-stranded RNA-specific editase B2 OS=Homo sapiens OX=9606 GN=ADARB2 PE=1 SV=1",0.071,1.211,1,1,1,1,739,80.6,10.17,2.45,1,"metabolic process","nucleus","catalytic activity;metal ion binding;RNA binding","Pf00035, Pf02137","105","ENSG00000185736.15","ADARB2","10","","","",0,0,"","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"Low","Master Protein","Q9UMX3","Bcl-2-related ovarian killer protein OS=Homo sapiens OX=9606 GN=BOK PE=1 SV=1",0.071,1.21,5,1,1,1,212,23.3,9.11,1.63,1,"cell death;cell differentiation;cell organization and biogenesis;cell proliferation;cellular homeostasis;metabolic process;regulation of biological process;response to stimulus","cytoplasm;endoplasmic reticulum;endosome;Golgi;membrane;mitochondrion;nucleus","protein binding","Pf00452","666","ENSG00000176720.4","BOK","2","Apoptosis - multiple species","","TP53 Network; Apoptosis; Regulation of Apoptosis by Parathyroid Hormone-related Protein",4,0,"","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"Low","Master Protein","O94886","CSC1-like protein 1 OS=Homo sapiens OX=9606 GN=TMEM63A PE=1 SV=3",0.071,1.206,1,1,2,1,807,92.1,7.27,3.34,1,"transport","membrane;vacuole","transporter activity","Pf02714, Pf13967, Pf14703","9725","ENSG00000196187.11","TMEM63A","1","","Neutrophil degranulation","",3,0,"","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"Low","Master Protein","P98174","FYVE, RhoGEF and PH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=FGD1 PE=1 SV=2",0.071,1.205,1,1,1,1,961,106.5,6.58,1.83,1,"cell organization and biogenesis;development;regulation of biological process;response to stimulus","cytoplasm;cytoskeleton;cytosol;Golgi","metal ion binding;protein binding","Pf00169, Pf00621, Pf01363, Pf15413","2245","ENSG00000102302.7","FGD1","X","Regulation of actin cytoskeleton","G alpha (12/13) signalling events; NRAGE signals death through JNK; Signalling by NGF; Rho GTPase cycle","Regulation of Actin Cytoskeleton",13,0,"","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"Low","Master Protein","O43781","Dual specificity tyrosine-phosphorylation-regulated kinase 3 OS=Homo sapiens OX=9606 GN=DYRK3 PE=1 SV=3",0.071,1.203,2,1,1,1,588,65.7,9.32,2.39,1,"cell differentiation;cell organization and biogenesis;metabolic process;regulation of biological process","cytoplasm;cytosol;nucleus","catalytic activity;metal ion binding;nucleotide binding","Pf00069, Pf01636, Pf07714","8444","ENSG00000143479.15","DYRK3","1","","","",0,0,"","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","Not Found","Not Found","Not Found","High","High","Not Found","Not Found","High","High","Not Found","Not Found",1,""]
[false,"Low","Master Protein","Q9UL45","Biogenesis of lysosome-related organelles complex 1 subunit 6 OS=Homo sapiens OX=9606 GN=BLOC1S6 PE=1 SV=1",0.072,1.198,5,1,1,1,172,19.7,6.4,2.87,1,"cell organization and biogenesis;cellular component movement;regulation of biological process;transport","cytoplasm;cytosol;membrane","protein binding","Pf14712","26258","ENSG00000104164.10","BLOC1S6","15","","Golgi Associated Vesicle Biogenesis","",5,0,"","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"Low","Master Protein","Q96C03","Mitochondrial dynamics protein MID49 OS=Homo sapiens OX=9606 GN=MIEF2 PE=1 SV=1",0.072,1.198,2,1,1,1,454,49.2,5.12,2.3,1,"cell organization and biogenesis;regulation of biological process","membrane;mitochondrion","protein binding","Pf03281","125170","ENSG00000177427.12; ENSG00000284495.1","SMCR7; MIEF2","17; CHR_HSCHR17_3_CTG1","","","",0,0,"","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"Low","Master Protein","P26544","Replication protein E1 OS=Human papillomavirus type 51 OX=10595 GN=E1 PE=3 SV=1",0.072,1.197,2,1,1,1,634,71.6,5.47,1.8,1,"metabolic process","","catalytic activity;DNA binding;nucleotide binding;RNA binding","Pf00519, Pf00524, Pf00910, Pf01057, Pf10236, Pf13207","","","","","","","",0,0,"","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"Low","Master Protein","O75414-3","Isoform 3 of Nucleoside diphosphate kinase 6 OS=Homo sapiens OX=9606 GN=NME6",0.072,1.197,14,1,1,1,163,18.1,8.87,0,1,"cell death;metabolic process;regulation of biological process","cytosol;mitochondrion","catalytic activity;metal ion binding;nucleotide binding","Pf00334","10201","ENSG00000172113.8","NME6","3","","","",0,0,"","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","Not Found","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"Low","Master Protein","Q5RHP9","Glutamate-rich protein 3 OS=Homo sapiens OX=9606 GN=ERICH3 PE=2 SV=1",0.072,1.196,1,1,1,1,1530,168.4,4.88,2.15,1,"","","","Pf15257","127254","ENSG00000178965.13","C1orf173; ERICH3","1","","","",0,0,"","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","Not Found","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"Low","Master Protein","O95409","Zinc finger protein ZIC 2 OS=Homo sapiens OX=9606 GN=ZIC2 PE=1 SV=2",0.073,1.192,2,1,1,1,532,55,8.41,2.11,1,"cell differentiation;development;metabolic process;regulation of biological process","cytoplasm;nucleus","DNA binding;metal ion binding","Pf00096, Pf13465","7546","ENSG00000043355.11","ZIC2","13","","","Mesodermal Commitment Pathway",1,0,"","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"Low","Master Protein","Q03001-11","Isoform 6 of Dystonin OS=Homo sapiens OX=9606 GN=DST",0.073,1.191,4,1,1,1,224,25.4,10.67,0,1,"cell organization and biogenesis;cellular component movement;regulation of biological process;response to stimulus;transport","cytoplasm;cytoskeleton;cytosol;membrane;nucleus","metal ion binding;protein binding","","667","","DST","6","","","",0,0,"","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","Not Found","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"Low","Master Protein","A6PVC2","Protein monoglycylase TTLL8 OS=Homo sapiens OX=9606 GN=TTLL8 PE=2 SV=4",0.073,1.191,2,1,1,1,850,94.6,8.21,0,1,"metabolic process","cytoplasm;cytoskeleton;cytosol","catalytic activity;nucleotide binding","Pf03133","164714","","TTLL8","22","","Carboxyterminal post-translational modifications of tubulin","",3,0,"","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"Low","Master Protein","Q8NA47","Coiled-coil domain-containing protein 63 OS=Homo sapiens OX=9606 GN=CCDC63 PE=2 SV=1",0.073,1.187,2,1,1,1,563,66.2,9.06,2.32,1,"cell differentiation;cell organization and biogenesis;cellular component movement","","","Pf03961","160762","ENSG00000173093.12","CCDC63","12","","","",0,0,"","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","Not Found","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"Low","Master Protein","Q7Z3Z4","Piwi-like protein 4 OS=Homo sapiens OX=9606 GN=PIWIL4 PE=1 SV=2",0.073,1.186,2,1,1,1,852,96.5,8.88,2.56,1,"cell differentiation;development;metabolic process;regulation of biological process","cytoplasm;nucleus","catalytic activity;protein binding;RNA binding","Pf02170, Pf02171","143689","ENSG00000134627.11","PIWIL4","11","Dorso-ventral axis formation","PIWI-interacting RNA (piRNA) biogenesis","",4,0,"","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","Not Found","Not Found","Not Found","High","High","High","Not Found","High","Not Found","Not Found","High",1,""]
[false,"Low","Master Protein","Q9BXF3","Cat eye syndrome critical region protein 2 OS=Homo sapiens OX=9606 GN=CECR2 PE=1 SV=2",0.073,1.185,1,1,1,1,1484,164.1,6.98,0,1,"cell organization and biogenesis;metabolic process;transport","nucleus","protein binding","Pf00439, Pf15614","27443","ENSG00000099954.18","CECR2","22","","","",0,0,"","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","Not Found","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"Low","Master Protein","O15260","Surfeit locus protein 4 OS=Homo sapiens OX=9606 GN=SURF4 PE=1 SV=3",0.075,1.183,4,1,1,1,269,30.4,7.78,0,1,"cell organization and biogenesis;regulation of biological process;transport","endoplasmic reticulum;Golgi;membrane","protein binding","Pf02077","6836","ENSG00000280951.2; ENSG00000148248.13","SURF4","9; CHR_HG2030_PATCH","","COPI-dependent Golgi-to-ER retrograde traffic; Neutrophil degranulation","",8,0,"","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"Low","Master Protein","P00750","Tissue-type plasminogen activator OS=Homo sapiens OX=9606 GN=PLAT PE=1 SV=1",0.076,1.178,2,1,1,1,562,62.9,7.8,1.91,1,"cellular component movement;coagulation;metabolic process;regulation of biological process;response to stimulus","cell surface;cytoplasm;extracellular","catalytic activity;protein binding","Pf00039, Pf00051, Pf00089, Pf09342","5327","ENSG00000104368.17","PLAT","8","Complement and coagulation cascades; Transcriptional misregulation in cancer","Dissolution of Fibrin Clot; Signaling by PDGF","Selenium Micronutrient Network; Vitamin B12 Metabolism; Folate Metabolism; Blood Clotting Cascade; NOTCH1 regulation of human endothelial cell calcification; Endochondral Ossification; Complement and Coagulation Cascades; Senescence and Autophagy in Cancer",15,0,"","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","Not Found","Not Found","High","Not Found","High","High","High","High","High","High","High",1,""]
[false,"Low","Master Protein","Q96JF6","Zinc finger protein 594 OS=Homo sapiens OX=9606 GN=ZNF594 PE=2 SV=3",0.076,1.177,1,1,1,1,807,93.8,8.7,1.76,1,"metabolic process;regulation of biological process","nucleus","DNA binding;metal ion binding","Pf13465","84622","ENSG00000180626.9","ZNF594","17","","","",0,0,"","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","Not Found","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"Low","Master Protein","Q9BW72","HIG1 domain family member 2A, mitochondrial OS=Homo sapiens OX=9606 GN=HIGD2A PE=1 SV=1",0.076,1.176,6,1,1,1,106,11.5,10.2,1.88,1,"metabolic process;regulation of biological process;transport","membrane;mitochondrion","","Pf04588","192286","ENSG00000146066.2","HIGD2A","5","","","",0,0,"","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"Low","Master Protein","Q49A17","Polypeptide N-acetylgalactosaminyltransferase-like 6 OS=Homo sapiens OX=9606 GN=GALNTL6 PE=2 SV=2",0.076,1.175,1,1,1,1,601,69.7,7.46,2.21,1,"metabolic process","Golgi;membrane","catalytic activity;metal ion binding","Pf00535, Pf00652, Pf02709, Pf13641","442117","ENSG00000174473.15","GALNTL6","4","Mucin type O-glycan biosynthesis; Metabolic pathways","O-linked glycosylation of mucins","",6,0,"","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"Low","Master Protein","Q96LR7","Uncharacterized protein C2orf50 OS=Homo sapiens OX=9606 GN=C2orf50 PE=1 SV=1",0.077,1.173,5,1,1,1,162,17.8,9.45,0,1,"","","protein binding","Pf14945","130813","ENSG00000150873.11","C2orf50","2","","","",0,0,"","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","Not Found","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"Low","Master Protein","Q6V0L0","Cytochrome P450 26C1 OS=Homo sapiens OX=9606 GN=CYP26C1 PE=2 SV=2",0.077,1.171,2,1,1,1,522,57.1,9,1.94,1,"cell organization and biogenesis;metabolic process;regulation of biological process","membrane","catalytic activity;metal ion binding","Pf00067","340665","ENSG00000187553.8","CYP26C1","10","Metabolic pathways; Retinol metabolism","Defective CYP26C1 causes Focal facial dermal dysplasia 4 (FFDD4); RA biosynthesis pathway; Vitamins","Oxidation by Cytochrome P450; Metapathway biotransformation",17,0,"","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"Low","Master Protein","O14771","Zinc finger protein 213 OS=Homo sapiens OX=9606 GN=ZNF213 PE=2 SV=2",0.077,1.168,4,1,1,1,459,51.2,6.95,2.54,1,"metabolic process;regulation of biological process","nucleus","DNA binding;metal ion binding","Pf00096, Pf01352, Pf02023, Pf13465","7760","ENSG00000085644.13","ZNF213","16","","Generic Transcription Pathway","",3,0,"","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","Not Found","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"Low","Master Protein","Q96FT7","Acid-sensing ion channel 4 OS=Homo sapiens OX=9606 GN=ASIC4 PE=1 SV=2",0.078,1.167,2,1,1,1,647,70.1,7.83,2.2,1,"transport","membrane","transporter activity","Pf00858","55515","ENSG00000072182.12","ASIC4","2","Inflammatory mediator regulation of TRP channels","Stimuli-sensing channels","",4,0,"","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"Low","Master Protein","Q9NSB4","Keratin, type II cuticular Hb2 OS=Homo sapiens OX=9606 GN=KRT82 PE=3 SV=3",0.078,1.162,1,1,1,1,513,56.6,6.74,2.19,1,"cell death","cytosol","structural molecule activity","Pf00038","3888","ENSG00000161850.2","KRT82","12","","Formation of the cornified envelope","",3,0,"","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"Low","Master Protein","Q5VVM6","Coiled-coil domain-containing protein 30 OS=Homo sapiens OX=9606 GN=CCDC30 PE=2 SV=1",0.078,1.16,1,1,1,1,783,91.3,5.77,1.79,1,"","","","","728621","ENSG00000186409.14","CCDC30","1","","","",0,0,"","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"Low","Master Protein","P0DO97","Coiled-coil domain-containing protein 192 OS=Homo sapiens OX=9606 GN=CCDC192 PE=4 SV=1",0.079,1.158,4,1,1,1,292,32.5,5.02,2.35,1,"","","","","728586","ENSG00000230561.4","LOC728586; LINC01183; CCDC192","5","","","",0,0,"","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"Low","Master Protein","Q96T25","Zinc finger protein ZIC 5 OS=Homo sapiens OX=9606 GN=ZIC5 PE=1 SV=2",0.079,1.157,1,1,1,1,663,68.4,8.76,2.11,1,"cell differentiation;development","nucleus","DNA binding;metal ion binding","Pf00096, Pf13465","85416","ENSG00000139800.8","ZIC5","13","","","Neural Crest Differentiation; Mesodermal Commitment Pathway",2,0,"","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","Not Found","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"Low","Master Protein","Q8N4B1","Sesquipedalian-1 OS=Homo sapiens OX=9606 GN=PHETA1 PE=1 SV=1",0.079,1.156,7,1,1,1,249,27.2,8.98,2.53,1,"cell organization and biogenesis;metabolic process;transport","cytosol;endosome;Golgi","protein binding","Pf00169, Pf15413","144717","ENSG00000198324.13","FAM109A","12","","","",0,0,"","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"Low","Master Protein","Q8IVF6","Ankyrin repeat domain-containing protein 18A OS=Homo sapiens OX=9606 GN=ANKRD18A PE=2 SV=3",0.079,1.156,1,1,1,1,992,115.5,7.83,2.74,1,"metabolic process","","protein binding","Pf00023, Pf04111, Pf12001, Pf12128, Pf12796, Pf13606, Pf13637, Pf13857, Pf14915","253650","ENSG00000180071.19","ANKRD18A","9","","","",0,0,"","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"Low","Master Protein","Q8N5J2","Ubiquitin carboxyl-terminal hydrolase MINDY-1 OS=Homo sapiens OX=9606 GN=MINDY1 PE=1 SV=2",0.079,1.156,1,1,1,1,469,51.7,4.86,2.14,1,"metabolic process","","catalytic activity;protein binding","Pf04424","55793","ENSG00000143409.15","FAM63A; MINDY1","1","","","",0,0,"","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"Low","Master Protein","Q13753","Laminin subunit gamma-2 OS=Homo sapiens OX=9606 GN=LAMC2 PE=1 SV=2",0.079,1.156,1,1,1,1,1193,130.9,6.19,0,1,"cell organization and biogenesis;metabolic process;regulation of biological process","extracellular;membrane","catalytic activity;motor activity","Pf00052, Pf00053, Pf01576, Pf05262, Pf05557, Pf08429, Pf12128, Pf13514","3918","ENSG00000058085.14","LAMC2","1","Small cell lung cancer; PI3K-Akt signaling pathway; Toxoplasmosis; Amoebiasis; ECM-receptor interaction; Focal adhesion; Pathways in cancer","Laminin interactions; Degradation of the extracellular matrix; MET activates PTK2 signaling; Type I hemidesmosome assembly; Anchoring fibril formation; Non-integrin membrane-ECM interactions","Alpha 6 Beta 4 signaling pathway; Focal Adhesion; Focal Adhesion-PI3K-Akt-mTOR-signaling pathway; Inflammatory Response Pathway",26,0,"","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"Low","Master Protein","Q8NBP5","Major facilitator superfamily domain-containing protein 9 OS=Homo sapiens OX=9606 GN=MFSD9 PE=2 SV=2",0.079,1.15,3,1,1,1,474,50.6,9.14,0,1,"transport","membrane","transporter activity","Pf07690","84804","ENSG00000135953.10","MFSD9","2","","","",0,0,"","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","Not Found","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"Low","Master Protein","Q9HBI6","Cytochrome P450 4F11 OS=Homo sapiens OX=9606 GN=CYP4F11 PE=1 SV=3",0.079,1.15,2,1,1,1,524,60.1,6.73,1.94,1,"coagulation;defense response;metabolic process;response to stimulus","endoplasmic reticulum;membrane","catalytic activity;metal ion binding","Pf00067","57834","ENSG00000171903.16","CYP4F11","19","","Eicosanoids; Synthesis of Leukotrienes (LT) and Eoxins (EX); Miscellaneous substrates; Fatty acids","Oxidation by Cytochrome P450; Metapathway biotransformation",13,0,"","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"Low","Master Protein","P0C6X1","Replicase polyprotein 1ab OS=Human coronavirus 229E OX=11137 GN=rep PE=1 SV=1",0.079,1.15,0,1,1,1,6758,753.7,6.9,2.03,1,"metabolic process;regulation of biological process;response to stimulus","membrane","catalytic activity;metal ion binding;nucleotide binding;RNA binding","Pf01661, Pf05409, Pf06460, Pf06471, Pf06478, Pf08710, Pf08715, Pf08716, Pf08717, Pf09401, Pf13086, Pf13087, Pf13538","918764","","HCoV229Egp1","","","","",0,0,"","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"Low","Master Protein","Q8TD23","Zinc finger protein 675 OS=Homo sapiens OX=9606 GN=ZNF675 PE=1 SV=3",0.079,1.15,2,1,1,1,568,66.3,8.87,1.8,1,"metabolic process;regulation of biological process;response to stimulus","nucleus","DNA binding;metal ion binding;protein binding","Pf01352, Pf13465","171392","ENSG00000197372.9","ZNF675","19","","Generic Transcription Pathway","",3,0,"","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","Not Found","Not Found","Not Found","High","High","Not Found","High","High","High","Not Found","High",1,""]
[false,"Low","Master Protein","Q8IWQ3","Serine/threonine-protein kinase BRSK2 OS=Homo sapiens OX=9606 GN=BRSK2 PE=1 SV=3",0.079,1.149,2,1,1,1,736,81.6,8.79,2.13,1,"cell death;cell differentiation;cell division;cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus;transport","cytoplasm;cytoskeleton;endoplasmic reticulum;nucleus","catalytic activity;enzyme regulator activity;metal ion binding;nucleotide binding;protein binding","Pf00069, Pf01633, Pf07714","9024","ENSG00000174672.15","BRSK2","11","","","",0,0,"","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"Low","Master Protein","Q9WT06","Protein U67 OS=Human herpesvirus 6B (strain Z29) OX=36351 GN=U67 PE=3 SV=1",0.08,1.146,3,1,1,1,353,39.6,8.12,0,1,"","","","Pf03038","1497067","","U67","","","","",0,0,"","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"Low","Master Protein","O14957","Cytochrome b-c1 complex subunit 10 OS=Homo sapiens OX=9606 GN=UQCR11 PE=1 SV=1",0.08,1.142,11,1,2,1,56,6.6,9.88,0,1,"metabolic process;transport","membrane;mitochondrion","catalytic activity;transporter activity","Pf08997","10975","ENSG00000127540.11; ENSG00000267059.2","UQCR11","19","Oxidative phosphorylation; Cardiac muscle contraction; Parkinson's disease; Non-alcoholic fatty liver disease (NAFLD); Alzheimer's disease; Huntington's disease; Metabolic pathways","Respiratory electron transport","Electron Transport Chain",12,0,"","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"Low","Master Protein","Q6NVH7","ATPase SWSAP1 OS=Homo sapiens OX=9606 GN=SWSAP1 PE=1 SV=1",0.081,1.14,4,1,1,1,229,24.3,5.21,2.18,1,"metabolic process;regulation of biological process;response to stimulus","nucleus","catalytic activity;DNA binding;protein binding","","126074","ENSG00000173928.2","SWSAP1","19","","","",0,0,"","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"Low","Master Protein","O95998","Interleukin-18-binding protein OS=Homo sapiens OX=9606 GN=IL18BP PE=1 SV=2",0.081,1.14,5,1,1,1,194,21.1,7.39,2.38,1,"regulation of biological process;response to stimulus","extracellular","protein binding","Pf05566","10068","ENSG00000137496.17","IL18BP","11","","Interleukin-18 signaling","",5,0,"","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","Not Found","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"Low","Master Protein","Q8TD57","Dynein heavy chain 3, axonemal OS=Homo sapiens OX=9606 GN=DNAH3 PE=2 SV=1",0.081,1.139,0,1,1,1,4116,470.5,6.43,2.59,1,"cell organization and biogenesis;cellular component movement","cytoplasm;cytoskeleton","catalytic activity;motor activity;nucleotide binding;protein binding","Pf03028, Pf07728, Pf08317, Pf08393, Pf12774, Pf12775, Pf12777, Pf12780, Pf12781","55567","ENSG00000158486.13","DNAH3","16","Huntington's disease","","",1,0,"","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"Low","Master Protein","Q9Y4F4","TOG array regulator of axonemal microtubules protein 1 OS=Homo sapiens OX=9606 GN=TOGARAM1 PE=1 SV=4",0.081,1.138,1,1,1,1,1720,189.2,8.5,3.09,1,"cell organization and biogenesis;regulation of biological process","cytoplasm;cytoskeleton","","","23116","ENSG00000198718.12","FAM179B; TOGARAM1","14","","","",0,0,"","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","Not Found","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"Low","Master Protein","Q6UYE1","Leukemia-associated protein 7 OS=Homo sapiens OX=9606 GN=DLEU7 PE=2 SV=1",0.082,1.137,6,1,1,1,221,23.9,7.88,2.02,1,"","","","","220107","ENSG00000186047.9","DLEU7","13","","","",0,0,"","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","Not Found","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"Low","Master Protein","A0A1B0GVQ3","Coiled-coil domain-containing protein 200 OS=Homo sapiens OX=9606 GN=CCDC200 PE=4 SV=1",0.082,1.137,8,1,1,1,168,19.4,9.22,2.41,1,"","","","","","ENSG00000236383.8","","17","","","",0,0,"","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","Not Found","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"Low","Master Protein","Q9NNZ6","Protamine-3 OS=Homo sapiens OX=9606 GN=PRM3 PE=3 SV=1",0.082,1.137,12,1,1,1,103,11.2,4.55,2.01,1,"cell differentiation;cell organization and biogenesis;cellular component movement;development;metabolic process","chromosome;cytoplasm;nucleus","DNA binding","","58531","","PRM3","16","","","",0,0,"","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"Low","Master Protein","A6NJZ7","RIMS-binding protein 3C OS=Homo sapiens OX=9606 GN=RIMBP3C PE=1 SV=3",0.082,1.136,1,1,1,1,1639,180.8,6.77,2.43,1,"","cytoplasm;cytoskeleton","protein binding","Pf00018, Pf00041, Pf07653, Pf14604","150221","ENSG00000183246.6","RIMBP3C","22","","","",0,0,"","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"Low","Master Protein","Q96GP6","Scavenger receptor class F member 2 OS=Homo sapiens OX=9606 GN=SCARF2 PE=1 SV=5",0.082,1.134,1,1,1,1,871,92.3,8.32,0,1,"","","","","","","","","","","",0,0,"","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"Low","Master Protein","Q7Z6M3","Allergin-1 OS=Homo sapiens OX=9606 GN=MILR1 PE=1 SV=2",0.082,1.133,5,1,1,1,343,38.7,7.77,2.11,1,"regulation of biological process;transport","membrane;vacuole","protein binding","Pf13895, Pf13927","284021","ENSG00000271605.5","MILR1","17","","","",0,0,"","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","Not Found","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"Low","Master Protein","Q9NUV7","Serine palmitoyltransferase 3 OS=Homo sapiens OX=9606 GN=SPTLC3 PE=1 SV=3",0.083,1.131,2,1,1,1,552,62,8.78,3.36,1,"metabolic process","endoplasmic reticulum;membrane","catalytic activity;protein binding","Pf00155, Pf01212","55304","ENSG00000172296.12","SPTLC3","20","Sphingolipid signaling pathway; Metabolic pathways; Sphingolipid metabolism","Sphingolipid de novo biosynthesis","Sphingolipid Metabolism",8,0,"","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"Low","Master Protein","P11468","Nucleoprotein OS=Dhori virus (strain Indian/1313/61) OX=11319 GN=P5 PE=3 SV=1",0.083,1.129,1,1,1,1,477,53.9,9.07,2.04,1,"transport","","structural molecule activity","Pf00506","","","","","","","",0,0,"","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"Low","Master Protein","Q9C0I3","Serine-rich coiled-coil domain-containing protein 1 OS=Homo sapiens OX=9606 GN=CCSER1 PE=2 SV=2",0.083,1.129,1,1,1,1,900,99.4,7.83,2.56,1,"","","","","401145","ENSG00000184305.14","CCSER1; FAM190A","4","","","",0,0,"","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","Not Found","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"Low","Master Protein","Q96D15","Reticulocalbin-3 OS=Homo sapiens OX=9606 GN=RCN3 PE=1 SV=1",0.083,1.127,3,1,1,1,328,37.5,4.89,2.07,1,"","endoplasmic reticulum;organelle lumen","metal ion binding;protein binding","Pf13499","57333","ENSG00000142552.7","RCN3","19","","","",0,0,"","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","Not Found","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"Low","Master Protein","Q9BS34","Zinc finger protein 670 OS=Homo sapiens OX=9606 GN=ZNF670 PE=1 SV=1",0.083,1.127,3,1,1,1,389,44.6,8.46,0,1,"metabolic process;regulation of biological process","nucleus","DNA binding;metal ion binding;protein binding","Pf01352, Pf13465","93474","ENSG00000277462.1","ZNF670","1","","Generic Transcription Pathway","",3,0,"","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","Not Found","Not Found","Not Found","Not Found","Not Found","Not Found","Not Found","Not Found","Not Found","Not Found","Not Found",1,""]
[false,"Low","Master Protein","P0DSW3","Serine proteinase inhibitor 2 OS=Variola virus (isolate Human/India/Ind3/1967) OX=587200 GN=SPI-2 PE=3 SV=1",0.083,1.127,4,1,1,1,344,38.4,5.01,0,1,"","","","","","","","","","","",0,0,"","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","Not Found","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"Low","Master Protein","Q96SD1","Protein artemis OS=Homo sapiens OX=9606 GN=DCLRE1C PE=1 SV=2",0.083,1.124,1,1,1,1,692,78.4,6.02,0,1,"cell differentiation;cell organization and biogenesis;metabolic process;response to stimulus","Golgi;nucleus","catalytic activity;DNA binding;protein binding","Pf00753, Pf07522, Pf12706","64421","ENSG00000152457.17","DCLRE1C","10","Non-homologous end-joining; Primary immunodeficiency","Nonhomologous End-Joining (NHEJ)","ATM Signaling Network in Development and Disease",6,0,"","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","Not Found","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"Low","Master Protein","Q9NR20","Dual specificity tyrosine-phosphorylation-regulated kinase 4 OS=Homo sapiens OX=9606 GN=DYRK4 PE=1 SV=2",0.083,1.123,2,1,1,1,520,59.6,8.9,0,1,"metabolic process","cytoplasm;nucleus","catalytic activity;metal ion binding;nucleotide binding;protein binding","Pf00069, Pf07714","8798","ENSG00000010219.13","DYRK4","12","","","",0,0,"","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"Low","Master Protein","Q5JPB2","Zinc finger protein 831 OS=Homo sapiens OX=9606 GN=ZNF831 PE=2 SV=4",0.083,1.123,0,1,1,1,1677,177.8,8.34,0,1,"development;metabolic process;regulation of biological process;response to stimulus","nucleus","DNA binding;metal ion binding","Pf00096, Pf13465","128611","ENSG00000124203.6","ZNF831","20","","","",0,0,"","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"Low","Master Protein","Q7Z745","Maestro heat-like repeat-containing protein family member 2B OS=Homo sapiens OX=9606 GN=MROH2B PE=2 SV=3",0.084,1.122,0,1,1,1,1585,180.7,6.28,2.06,1,"cell differentiation;regulation of biological process;response to stimulus","cytoplasm","","","133558","ENSG00000171495.16","HEATR7B2; MROH2B","5","","","",0,0,"","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"Low","Master Protein","A8K2U0","Alpha-2-macroglobulin-like protein 1 OS=Homo sapiens OX=9606 GN=A2ML1 PE=1 SV=3",0.083,1.122,1,1,1,1,1454,161,5.73,2.05,1,"regulation of biological process","extracellular","enzyme regulator activity","Pf00207, Pf01835, Pf05326, Pf07677, Pf07678, Pf07703, Pf10569, Pf13249","144568","ENSG00000166535.19","A2ML1","12","","","",0,0,"","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"Low","Master Protein","Q96GR4","Probable palmitoyltransferase ZDHHC12 OS=Homo sapiens OX=9606 GN=ZDHHC12 PE=2 SV=2",0.085,1.119,3,1,1,1,267,30.8,7.2,2.2,1,"metabolic process","endoplasmic reticulum;Golgi;membrane","catalytic activity;metal ion binding","Pf01529","84885","ENSG00000160446.18","ZDHHC12","9","","","",0,0,"","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","Not Found","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"Low","Master Protein","Q96SL8","Flt3-interacting zinc finger protein 1 OS=Homo sapiens OX=9606 GN=FIZ1 PE=1 SV=2",0.085,1.117,1,1,1,1,496,52,8.19,2.17,1,"metabolic process;regulation of biological process","cytoplasm;nucleus","metal ion binding;protein binding","Pf13465","84922","ENSG00000179943.7","FIZ1","19","","","",0,0,"","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","Not Found","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"Low","Master Protein","Q8IWV1","Lymphocyte transmembrane adapter 1 OS=Homo sapiens OX=9606 GN=LAX1 PE=1 SV=1",0.085,1.117,2,1,1,1,398,44.1,4.97,2.47,1,"regulation of biological process;response to stimulus;transport","cytosol;Golgi;membrane","protein binding","","54900","ENSG00000122188.12","LAX1","1","","","",0,0,"","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","High","High","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"Low","Master Protein","Q7Z3H4","Sterile alpha motif domain-containing protein 7 OS=Homo sapiens OX=9606 GN=SAMD7 PE=1 SV=1",0.086,1.112,3,1,1,1,446,49.1,6.8,2.66,1,"","cytoplasm;nucleus","protein binding","Pf00536, Pf07647","344658","ENSG00000187033.9","SAMD7","3","","","",0,0,"","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"Low","Master Protein","Q08778","Outer capsid protein VP4 OS=Rotavirus A (isolate RVA/Human/Thailand/Mc35/1992/G10P11[14]) OX=37136 PE=2 SV=1",0.086,1.112,1,1,1,1,776,86.8,5.2,0,1,"","","","Pf00426","","","","","","","",0,0,"","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","Not Found","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"Low","Master Protein","P08805","Protein Vpu OS=Human immunodeficiency virus type 1 group M subtype U (isolate Z3) OX=11680 GN=vpu PE=3 SV=2",0.086,1.112,9,1,1,1,81,9.5,4.53,2.62,1,"cell death;metabolic process;regulation of biological process;response to stimulus;transport","membrane","protein binding;transporter activity","Pf00558","","","","","","","",0,0,"","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"Low","Master Protein","Q0ZME6","Non-structural protein 4 OS=Human coronavirus HKU1 (isolate N5) OX=443241 GN=4 PE=3 SV=1",0.086,1.111,17,1,1,1,109,12.6,8.06,0,1,"","","","Pf04753","","","","","","","",0,0,"","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","Not Found","Not Found","Not Found","Not Found","Not Found","Not Found","Not Found","Not Found","Not Found","Not Found","Not Found",1,""]
[false,"Low","Master Protein","P49765","Vascular endothelial growth factor B OS=Homo sapiens OX=9606 GN=VEGFB PE=1 SV=2",0.086,1.109,5,1,1,1,207,21.6,8.15,2.38,1,"metabolic process;regulation of biological process;response to stimulus;transport","extracellular;membrane;organelle lumen","protein binding","Pf00341","7423","ENSG00000173511.9","VEGFB","11","Focal adhesion; Rap1 signaling pathway; PI3K-Akt signaling pathway; AGE-RAGE signaling pathway in diabetic complications; Cytokine-cytokine receptor interaction; Ras signaling pathway; Pathways in cancer","Platelet degranulation ; VEGF binds to VEGFR leading to receptor dimerization","Heart Development; Focal Adhesion; miR-148a/miR-31/FIH1/HIF1alpha-Notch signaling in glioblastoma; Focal Adhesion-PI3K-Akt-mTOR-signaling pathway",20,0,"","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","Not Found","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"Low","Master Protein","Q9Y238","Deleted in lung and esophageal cancer protein 1 OS=Homo sapiens OX=9606 GN=DLEC1 PE=2 SV=2",0.086,1.109,1,1,1,1,1755,195.6,6.33,0,1,"regulation of biological process","cytoplasm;cytosol","","Pf09321","9940","ENSG00000008226.19","DLEC1","3","","","",0,0,"","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","Not Found","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"Low","Master Protein","Q9NYF3","Protein FAM53C OS=Homo sapiens OX=9606 GN=FAM53C PE=1 SV=1",0.087,1.108,2,1,1,1,392,43.1,8.65,2.15,1,"","","protein binding","Pf15242","51307","ENSG00000120709.10","FAM53C","5","","","",0,0,"","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"Low","Master Protein","O95477","Phospholipid-transporting ATPase ABCA1 OS=Homo sapiens OX=9606 GN=ABCA1 PE=1 SV=3",0.087,1.105,1,1,1,1,2261,254.1,6.86,0,1,"cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus;transport","cell surface;Golgi;membrane","catalytic activity;nucleotide binding;protein binding;receptor activity;signal transducer activity;transporter activity","Pf00005, Pf12698, Pf13304, Pf13732","19","ENSG00000165029.15","ABCA1","9","ABC transporters; Fat digestion and absorption","Defective ABCA1 causes Tangier disease; PPARA activates gene expression; HDL assembly","Selenium Micronutrient Network; Vitamin B12 Metabolism; Folate Metabolism; SREBF and miR33 in cholesterol and lipid homeostasis; Nuclear Receptors in Lipid Metabolism and Toxicity; Statin Pathway",20,0,"","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","Not Found","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"Low","Master Protein","P41586","Pituitary adenylate cyclase-activating polypeptide type I receptor OS=Homo sapiens OX=9606 GN=ADCYAP1R1 PE=1 SV=1",0.087,1.105,1,1,1,1,468,53.3,5.78,2.67,1,"cell differentiation;development;regulation of biological process;response to stimulus;transport","cell surface;cytoplasm;endoplasmic reticulum;endosome;membrane","protein binding;receptor activity;signal transducer activity","Pf00002, Pf02793","117","ENSG00000078549.14","ADCYAP1R1","7","Renin secretion; cAMP signaling pathway; Neuroactive ligand-receptor interaction; Insulin secretion; Circadian entrainment","G alpha (s) signalling events; Glucagon-type ligand receptors; NGF-independant TRKA activation","GPCRs, Class B Secretin-like; Sudden Infant Death Syndrome (SIDS) Susceptibility Pathways",19,0,"","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","Not Found","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"Low","Master Protein","O75747","Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gamma OS=Homo sapiens OX=9606 GN=PIK3C2G PE=1 SV=3",0.087,1.104,1,1,1,1,1445,165.6,6.93,3.15,1,"cellular component movement;metabolic process;regulation of biological process;response to stimulus","cytoplasm;cytosol;membrane","catalytic activity;nucleotide binding;protein binding","Pf00168, Pf00454, Pf00613, Pf00787, Pf00792, Pf00794","5288","ENSG00000139144.9","PIK3C2G","12","Phosphatidylinositol signaling system; Inositol phosphate metabolism; Metabolic pathways","Synthesis of PIPs at the plasma membrane; Synthesis of PIPs at the Golgi membrane","Signaling Pathways in Glioblastoma; Angiopoietin Like Protein 8 Regulatory Pathway; Insulin Signaling; Regulation of Actin Cytoskeleton; DNA Damage Response (only ATM dependent)",14,0,"","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"Low","Master Protein","Q9H2B2","Synaptotagmin-4 OS=Homo sapiens OX=9606 GN=SYT4 PE=1 SV=1",0.087,1.103,2,1,1,1,425,47.9,8.53,1.95,1,"cell differentiation;cell organization and biogenesis;regulation of biological process;response to stimulus;transport","Golgi;membrane","metal ion binding;protein binding","Pf00168","6860","ENSG00000132872.11","SYT4","18","","","",0,0,"","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"Low","Master Protein","Q969L4","U7 snRNA-associated Sm-like protein LSm10 OS=Homo sapiens OX=9606 GN=LSM10 PE=1 SV=1",0.093,1.091,5,1,1,1,123,14.1,9.25,1.76,1,"metabolic process;regulation of biological process","nucleus","protein binding;RNA binding","Pf01423","84967","ENSG00000181817.5","LSM10","1","","Cleavage of Growing Transcript in the Termination Region ; SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs; SLBP independent Processing of Histone Pre-mRNAs","",8,0,"","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","Not Found","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"Low","Master Protein","Q5MJ08","Sperm protein associated with the nucleus on the X chromosome N4 OS=Homo sapiens OX=9606 GN=SPANXN4 PE=3 SV=1",0.093,1.088,19,1,1,1,99,11.2,9.19,0,1,"","","","Pf07458","441525","ENSG00000189326.4","SPANXN4","X","","","",0,0,"","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","Not Found","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"Low","Master Protein","P10745","Retinol-binding protein 3 OS=Homo sapiens OX=9606 GN=RBP3 PE=1 SV=2",0.093,1.086,1,1,1,1,1247,135.3,5.11,2,1,"metabolic process;transport","extracellular","catalytic activity","Pf03572, Pf11918","5949","ENSG00000265203.1","RBP3","10","","Signaling by GPCR; The canonical retinoid cycle in rods (twilight vision); The retinoid cycle in cones (daylight vision)","",5,0,"","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","Not Found","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"Low","Master Protein","Q5T4D3","Protein O-mannosyl-transferase TMTC4 OS=Homo sapiens OX=9606 GN=TMTC4 PE=1 SV=2",0.094,1.084,1,1,1,1,741,82.9,8.94,2.71,1,"","membrane","protein binding","Pf00515, Pf07719, Pf08409, Pf13181, Pf13414, Pf13424, Pf13431, Pf13432, Pf14559","84899","ENSG00000125247.15","TMTC4","13","","","",0,0,"","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","Not Found","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"Low","Master Protein","Q82007","Replication protein E1 OS=Human papillomavirus type 73 OX=51033 GN=E1 PE=3 SV=1",0.094,1.083,3,1,1,1,650,73.5,5.74,0,1,"metabolic process","","catalytic activity;DNA binding;nucleotide binding","Pf00519, Pf00524","","","","","","","",0,0,"","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"Low","Master Protein","A6NNW6","Enolase 4 OS=Homo sapiens OX=9606 GN=ENO4 PE=2 SV=4",0.094,1.081,2,1,1,1,625,68.4,5.91,2.32,1,"","","","","","","","","","","",0,0,"","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"Low","Master Protein","Q9BZF2","Oxysterol-binding protein-related protein 7 OS=Homo sapiens OX=9606 GN=OSBPL7 PE=1 SV=1",0.095,1.08,1,1,1,1,842,95.4,8.05,2.02,1,"metabolic process;regulation of biological process;response to stimulus;transport","cytoplasm;cytosol;endoplasmic reticulum;membrane;vacuole","protein binding;transporter activity","Pf00169, Pf01237, Pf15409","114881","ENSG00000006025.11","OSBPL7","17","","Synthesis of bile acids and bile salts","",5,0,"","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","Not Found","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"Low","Master Protein","Q9Y2C9","Toll-like receptor 6 OS=Homo sapiens OX=9606 GN=TLR6 PE=1 SV=2",0.095,1.079,2,1,1,1,796,91.8,7.23,0,1,"defense response;metabolic process;regulation of biological process;response to stimulus;transport","Golgi;membrane","protein binding;receptor activity;signal transducer activity","Pf01582, Pf12799, Pf13676, Pf13855","10333","ENSG00000174130.12","TLR6","4","Chagas disease (American trypanosomiasis); Phagosome; Toll-like receptor signaling pathway; Tuberculosis","MyD88:Mal cascade initiated on plasma membrane; Regulation of TLR by endogenous ligand; IRAK4 deficiency (TLR2/4); ER-Phagosome pathway; MyD88 deficiency (TLR2/4); Activated TLR4 signalling","Regulation of toll-like receptor signaling pathway; Toll-like Receptor Signaling; Simplified Depiction of MYD88 Distinct Input-Output Pathway; Toll-like receptor signaling pathway",27,0,"","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"Low","Master Protein","Q9HAY2","Melanoma-associated antigen F1 OS=Homo sapiens OX=9606 GN=MAGEF1 PE=1 SV=2",0.095,1.079,3,1,1,1,307,35.2,9.72,1.61,1,"","","protein binding","Pf01454","64110","ENSG00000177383.4","MAGEF1","3","","","",0,0,"","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","Not Found","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"Low","Master Protein","Q9NR83","SLC2A4 regulator OS=Homo sapiens OX=9606 GN=SLC2A4RG PE=1 SV=4",0.095,1.078,2,1,1,1,387,41.2,8.24,2.01,1,"metabolic process;regulation of biological process","cytoplasm;nucleus","DNA binding;metal ion binding","","56731","ENSG00000125520.13","SLC2A4RG","20","","","AMP-activated Protein Kinase (AMPK) Signaling",1,0,"","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"Low","Master Protein","Q9QJ52","Protein U8 OS=Human herpesvirus 6B (strain Z29) OX=36351 GN=U8 PE=4 SV=1",0.095,1.078,4,1,1,1,411,47.6,8,2.17,1,"","","","Pf02393","1497020","","U8","","","","",0,0,"","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"Low","Master Protein","Q15413","Ryanodine receptor 3 OS=Homo sapiens OX=9606 GN=RYR3 PE=1 SV=3",0.095,1.078,0,1,1,1,4870,551.7,5.68,2.08,1,"cell organization and biogenesis;cellular homeostasis;regulation of biological process;response to stimulus;transport","endoplasmic reticulum;membrane","metal ion binding;protein binding;transporter activity","Pf00622, Pf01365, Pf02026, Pf02815, Pf06459, Pf08454, Pf08709, Pf13833","6263","ENSG00000198838.13","RYR3","15","Oxytocin signaling pathway; Alzheimer's disease; Salivary secretion; Circadian entrainment; Calcium signaling pathway","Ion homeostasis; Stimuli-sensing channels","Alzheimers Disease; Myometrial Relaxation and Contraction Pathways; MFAP5-mediated ovarian cancer cell motility and invasiveness; Cell-type Dependent Selectivity of CCK2R Signaling; Calcium Regulation in the Cardiac Cell",16,0,"","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"Low","Master Protein","P22422","Protein E6 OS=Human papillomavirus type 47 OX=10594 GN=E6 PE=3 SV=1",0.095,1.076,8,1,1,1,156,18.1,6.29,0,1,"metabolic process;regulation of biological process;response to stimulus","","DNA binding;metal ion binding","Pf00518","","","","","","","",0,0,"","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"Low","Master Protein","Q6ZP65","BICD family-like cargo adapter 1 OS=Homo sapiens OX=9606 GN=BICDL1 PE=2 SV=2",0.096,1.073,2,1,1,1,573,64.8,5,2.13,1,"cell organization and biogenesis;transport","cytoplasm;cytoskeleton","protein binding","Pf04156, Pf04849, Pf06785, Pf12128","92558","ENSG00000135127.11","CCDC64; BICDL1","12","","","",0,0,"","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","Not Found","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"Low","Master Protein","Q9QJ30","Capsid scaffolding protein OS=Human herpesvirus 6B (strain Z29) OX=36351 GN=U53 PE=3 SV=1",0.096,1.071,1,1,1,1,528,58.8,5.76,1.99,1,"cell organization and biogenesis;metabolic process","","catalytic activity","Pf00716","1497055","","U53","","","","",0,0,"","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"Low","Master Protein","O60636","Tetraspanin-2 OS=Homo sapiens OX=9606 GN=TSPAN2 PE=1 SV=2",0.096,1.07,3,1,1,1,221,24.1,7.77,0,1,"cell differentiation;cell organization and biogenesis;defense response;regulation of biological process;response to stimulus","membrane","protein binding","Pf00335","10100","ENSG00000134198.9","TSPAN2","1","","","",0,0,"","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"Low","Master Protein","E7EU14","Protein PPP5D1 OS=Homo sapiens OX=9606 GN=PPP5D1 PE=2 SV=2",0.097,1.07,8,1,1,1,171,19.6,9.31,0,1,"","","","Pf08321","100506012","ENSG00000230510.6","PPP5D1","19","","","",0,0,"","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"Low","Master Protein","Q96LX7","Coiled-coil domain-containing protein 17 OS=Homo sapiens OX=9606 GN=CCDC17 PE=1 SV=2",0.097,1.067,1,1,1,1,622,67.7,7.18,2.29,1,"","","protein binding","","149483","ENSG00000159588.14","CCDC17","1","","","",0,0,"","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"Low","Master Protein","Q9QBY3","Gag-Pol polyprotein OS=Human immunodeficiency virus type 1 group M subtype K (isolate 96CM-MP535) OX=388906 GN=gag-pol PE=3 SV=3",0.097,1.066,1,1,1,1,1430,161.4,8.63,1.84,1,"metabolic process;regulation of biological process;transport","membrane","catalytic activity;DNA binding;metal ion binding;RNA binding;structural molecule activity","Pf00075, Pf00077, Pf00078, Pf00098, Pf00540, Pf00552, Pf00607, Pf00665, Pf02022, Pf06815, Pf06817, Pf13650","","","","","","","",0,0,"","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","Not Found","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"Low","Master Protein","Q9NYF0","Dapper homolog 1 OS=Homo sapiens OX=9606 GN=DACT1 PE=1 SV=2",0.097,1.065,1,1,1,1,836,90.1,8.69,2.65,1,"development;regulation of biological process;response to stimulus","cytoplasm;cytosol;nucleus","protein binding","Pf15268","51339","ENSG00000165617.14","DACT1","14","","Degradation of DVL","",4,0,"","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","Not Found","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"Low","Master Protein","Q9H741","UPF0454 protein C12orf49 OS=Homo sapiens OX=9606 GN=C12orf49 PE=1 SV=1",0.097,1.065,6,1,1,1,205,23.6,8.1,1.91,1,"","extracellular","protein binding","Pf10218","79794","ENSG00000111412.5","C12orf49","12","","","",0,0,"","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","Not Found","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"Low","Master Protein","P06681","Complement C2 OS=Homo sapiens OX=9606 GN=C2 PE=1 SV=2",0.097,1.063,1,1,1,1,752,83.2,7.42,2.42,1,"defense response;metabolic process;regulation of biological process;response to stimulus","extracellular","catalytic activity;metal ion binding;protein binding","Pf00084, Pf00089, Pf00092, Pf09342, Pf13519","717","ENSG00000231543.9; ENSG00000204364.10; ENSG00000226560.10; ENSG00000235696.8; ENSG00000166278.14; ENSG00000235017.9; ENSG00000206372.11","C2","6; CHR_HSCHR6_MHC_DBB_CTG1; CHR_HSCHR6_MHC_MANN_CTG1; CHR_HSCHR6_MHC_MCF_CTG1; CHR_HSCHR6_MHC_SSTO_CTG1; CHR_HSCHR6_MHC_COX_CTG1; CHR_HSCHR6_MHC_QBL_CTG1","Staphylococcus aureus infection; Pertussis; Complement and coagulation cascades; Systemic lupus erythematosus","Initial triggering of complement; Regulation of Complement cascade; Activation of C3 and C5","Allograft Rejection; Oxidative Damage; Complement Activation; Complement and Coagulation Cascades",14,0,"","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","Not Found","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"Low","Master Protein","Q9UPG8","Zinc finger protein PLAGL2 OS=Homo sapiens OX=9606 GN=PLAGL2 PE=2 SV=1",0.098,1.059,1,1,1,1,496,54.5,8.65,1.7,1,"cell death;cell organization and biogenesis;metabolic process;regulation of biological process","nucleus","DNA binding;metal ion binding","Pf00096, Pf13465","5326","ENSG00000126003.6","PLAGL2","20","","","",0,0,"","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"Low","Master Protein","Q5SZQ8","CUGBP Elav-like family member 3 OS=Homo sapiens OX=9606 GN=CELF3 PE=1 SV=1",0.099,1.058,6,1,1,1,465,50.5,8.53,0,1,"cell organization and biogenesis;cellular component movement;metabolic process;regulation of biological process","cytoplasm;nucleus","RNA binding","Pf00076, Pf13893, Pf14259","11189","ENSG00000159409.14","CELF3","1","","","Preimplantation Embryo",1,0,"","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"Low","Master Protein","P55268","Laminin subunit beta-2 OS=Homo sapiens OX=9606 GN=LAMB2 PE=1 SV=2",0.099,1.057,1,1,1,1,1798,195.9,6.52,2.26,1,"cell growth;cell organization and biogenesis;cellular component movement;metabolic process;regulation of biological process;transport","cytoplasm;extracellular;Golgi;organelle lumen","catalytic activity;motor activity;nucleotide binding;protein binding;structural molecule activity;transporter activity","Pf00053, Pf00055, Pf00430, Pf00769, Pf01576, Pf02050, Pf02841, Pf04111, Pf06008, Pf09831, Pf12128, Pf12795, Pf13514, Pf13851, Pf13868, Pf15070, Pf15558","3913","ENSG00000172037.13","LAMB2","3","Amoebiasis; Small cell lung cancer; Pathways in cancer; PI3K-Akt signaling pathway; Focal adhesion; ECM-receptor interaction; Toxoplasmosis","ECM proteoglycans; Post-translational protein phosphorylation; Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs); Laminin interactions; MET activates PTK2 signaling; Non-integrin membrane-ECM interactions","Alpha 6 Beta 4 signaling pathway; Primary Focal Segmental Glomerulosclerosis FSGS; miRNA targets in ECM and membrane receptors; Focal Adhesion; Focal Adhesion-PI3K-Akt-mTOR-signaling pathway; Inflammatory Response Pathway",26,0,"","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","Not Found","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"Low","Master Protein","Q9BZJ6","Probable G-protein coupled receptor 63 OS=Homo sapiens OX=9606 GN=GPR63 PE=2 SV=2",0.099,1.057,7,1,1,1,419,47.5,9.52,0,1,"regulation of biological process;response to stimulus","cytosol;membrane;nucleus","receptor activity;signal transducer activity;transporter activity","Pf00001, Pf01032","81491","ENSG00000112218.8","GPR63","6","","","GPCRs, Class A Rhodopsin-like",1,0,"","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"Low","Master Protein","Q92637","High affinity immunoglobulin gamma Fc receptor IB OS=Homo sapiens OX=9606 GN=FCGR1B PE=2 SV=1",0.099,1.056,4,1,1,1,280,32.2,8.68,0,1,"regulation of biological process;response to stimulus;transport","membrane","protein binding;receptor activity;signal transducer activity","Pf00047, Pf07686, Pf13895, Pf13927","2210","","FCGR1B","1","","Cross-presentation of soluble exogenous antigens (endosomes); Interferon gamma signaling","",8,0,"","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","Not Found","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"Low","Master Protein","Q6UXV1","Izumo sperm-egg fusion protein 2 OS=Homo sapiens OX=9606 GN=IZUMO2 PE=2 SV=1",0.1,1.053,5,1,1,1,221,24.8,8.79,2.18,1,"","membrane;nucleus","","Pf15005","126123","ENSG00000161652.12","IZUMO2","19","","Sperm:Oocyte Membrane Binding","",3,0,"","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"Low","Master Protein","O94759","Transient receptor potential cation channel subfamily M member 2 OS=Homo sapiens OX=9606 GN=TRPM2 PE=1 SV=2",0.1,1.053,0,1,1,1,1503,171.1,7.5,0,1,"cell differentiation;cellular component movement;cellular homeostasis;regulation of biological process;response to stimulus;transport","membrane;vacuole","catalytic activity;metal ion binding;transporter activity","Pf00520","7226","ENSG00000142185.16","TRPM2","21","Oxytocin signaling pathway; NOD-like receptor signaling pathway","TRP channels; Neutrophil degranulation","Ectoderm Differentiation",10,0,"","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"Low","Master Protein","Q9NSD4","Zinc finger protein 275 OS=Homo sapiens OX=9606 GN=ZNF275 PE=1 SV=2",0.1,1.053,4,1,1,1,429,48.4,9.09,2.49,1,"metabolic process;regulation of biological process","nucleus","DNA binding;metal ion binding","Pf00096, Pf13465","10838","","ZNF275","X","","","",0,0,"","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","Not Found","Not Found","Not Found","High","High","High","Not Found","High","Not Found","High","High",1,""]
[false,"Low","Master Protein","Q96FE7","Phosphoinositide-3-kinase-interacting protein 1 OS=Homo sapiens OX=9606 GN=PIK3IP1 PE=1 SV=2",0.1,1.052,4,1,1,1,263,28.2,5.01,1.76,1,"regulation of biological process","membrane","protein binding","Pf00051","113791","ENSG00000100100.12","PIK3IP1","22","","","Focal Adhesion-PI3K-Akt-mTOR-signaling pathway",1,0,"","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","Not Found","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"Low","Master Protein","P08183","ATP-dependent translocase ABCB1 OS=Homo sapiens OX=9606 GN=ABCB1 PE=1 SV=3",0.1,1.051,1,1,1,1,1280,141.4,9,0,1,"cell organization and biogenesis;cell proliferation;regulation of biological process;response to stimulus;transport","cell surface;membrane","catalytic activity;nucleotide binding;protein binding;transporter activity","Pf00005, Pf00664, Pf09818, Pf13558","5243","ENSG00000085563.14","ABCB1","7","MicroRNAs in cancer; Bile secretion; ABC transporters","Abacavir transmembrane transport; ABC-family proteins mediated transport","Codeine and Morphine Metabolism; Drug Induction of Bile Acid Pathway; Allograft Rejection; Constitutive Androstane Receptor Pathway; Nuclear Receptors in Lipid Metabolism and Toxicity; Imatinib and Chronic Myeloid Leukemia; LncRNA-mediated mechanisms of therapeutic resistance",15,0,"","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","Not Found","Not Found","Not Found","Not Found","High","Not Found","Not Found","Not Found","Not Found","Not Found","High",1,""]
[false,"Low","Master Protein","O89942","Protein Vpr OS=Human immunodeficiency virus type 1 group M subtype G (isolate SE6165) OX=388824 GN=vpr PE=3 SV=1",0.1,1.05,6,1,2,1,96,11.3,7.05,3.35,1,"cell death;metabolic process;regulation of biological process;transport","","transporter activity","Pf00522","","","","","","","",0,0,"","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"Low","Master Protein","P26543","Replication protein E1 OS=Human papillomavirus type 58 OX=10598 GN=E1 PE=3 SV=1",0.102,1.049,2,1,1,1,644,72.2,5.3,1.65,1,"metabolic process","","catalytic activity;DNA binding;nucleotide binding","Pf00519, Pf00524, Pf01057","","","","","","","",0,0,"","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","Not Found","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"Low","Master Protein","F5HAW0","Ribonucleoside-diphosphate reductase small subunit OS=Human herpesvirus 8 type P (isolate GK18) OX=868565 GN=RIR2 PE=3 SV=1",0.103,1.045,2,1,1,1,305,35,5.92,2.16,1,"metabolic process","membrane","catalytic activity;metal ion binding","Pf00268","4961455","","ORF60","","","","",0,0,"","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"Low","Master Protein","Q9Y2L6","FERM domain-containing protein 4B OS=Homo sapiens OX=9606 GN=FRMD4B PE=1 SV=4",0.103,1.044,1,1,1,1,1034,118,8.62,2.49,1,"","cytoplasm;cytoskeleton","","Pf00373, Pf09379, Pf09380, Pf11819","23150","ENSG00000114541.14","FRMD4B","3","","","",0,0,"","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","Not Found","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"Low","Master Protein","Q6ZV56-2","Isoform 2 of Putative uncharacterized protein C22orf34 OS=Homo sapiens OX=9606 GN=C22orf34",0.103,1.043,6,1,1,1,183,20.4,7.91,1.86,1,"","","","","348645","","C22orf34","22","","","",0,0,"","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","Not Found","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"Low","Master Protein","Q9ULW2","Frizzled-10 OS=Homo sapiens OX=9606 GN=FZD10 PE=1 SV=1",0.103,1.041,2,1,1,1,581,65.3,8.47,0,1,"cell differentiation;development;regulation of biological process;response to stimulus","cell surface;cytoplasm;membrane","protein binding;receptor activity;signal transducer activity","Pf01392, Pf01534","11211","ENSG00000111432.4","FZD10","12","mTOR signaling pathway; HTLV-I infection; Wnt signaling pathway; Breast cancer; Basal cell carcinoma; Proteoglycans in cancer; Melanogenesis; Pathways in cancer; Signaling pathways regulating pluripotency of stem cells; Hippo signaling pathway","Class B/2 (Secretin family receptors)","Association Between Physico-Chemical Features and Toxicity Associated Pathways; Wnt Signaling Pathway and Pluripotency; Wnt Signaling Pathway",17,0,"","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"Low","Master Protein","Q6IQ16","Speckle-type POZ protein-like OS=Homo sapiens OX=9606 GN=SPOPL PE=1 SV=1",0.103,1.041,2,1,1,1,392,44.6,7.28,1.93,1,"metabolic process;regulation of biological process","cytoplasm;nucleus","protein binding","Pf00651, Pf00917","339745","ENSG00000144228.8","SPOPL","2","Hedgehog signaling pathway","Hedgehog 'on' state","",4,0,"","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","High","Not Found","Not Found","High","High","High","High","High","High","High","High",1,""]
[false,"Low","Master Protein","Q8NET4","Retrotransposon Gag-like protein 9 OS=Homo sapiens OX=9606 GN=RTL9 PE=1 SV=1",0.103,1.04,1,1,1,1,1388,144.2,6.16,0,1,"","","","Pf03732","57529","ENSG00000243978.8","RGAG1; RTL9","X","","","",0,0,"","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","Not Found","Not Found","Not Found","Not Found","Not Found","High","High","Not Found","Not Found","High","Not Found",1,""]
[false,"Low","Master Protein","Q6E0U4","Dermokine OS=Homo sapiens OX=9606 GN=DMKN PE=1 SV=3",0.103,1.04,2,1,1,1,476,47.1,7.28,1.99,1,"","extracellular","protein binding","","93099","ENSG00000161249.20","DMKN","19","","","",0,0,"","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","Not Found","Not Found","Not Found","High","High","High","High","Not Found","High","High","High",1,""]