{"text_format":"3","workbook":"xlsx","n_sheets":3,"sheets":["Sheet1","Sheet2","Sheet3"],"read":"whole","date_system":"1900"}

{"sheet":"Sheet1","index":0,"n_rows":851,"n_cols":4,"rows_kept":851}
["Notation","Reaction","kj","Units"]
["R1","R + EGF -> Rl",0.01,"1/(nM*s)"]
["R2","Rl -> R + EGF",1,"1/s"]
["R3","Rl + Rl -> Rl2",0.01,"1/(nM*s)"]
["R4","Rl2 -> Rl + Rl",0.1,"1/s"]
["R5","Rl2 -> Rl2P",1,"1/s"]
["R6","RP + PLCy -> RP_PL",0.06,"1/(nM*s)"]
["R7","RP_PL -> RP + PLCy",0.2,"1/s"]
["R8","RP_PL -> RP_PLP",1,"1/s"]
["R9","RP_PLP -> RP + PLCyP",0.3,"1/s"]
["R10","RP + PLCyP -> RP_PLP",0.006,"1/(nM*s)"]
["R11","RP + Grb -> RP_G",0.0015,"1/(nM*s)"]
["R12","RP_G -> RP + Grb",0.2,"1/s"]
["R13","RP_G + SOS -> RP_G_S",0.01,"1/(nM*s)"]
["R14","RP_G_S -> RP_G + SOS",0.06,"1/s"]
["R15","RP_G_S -> RP + G_S",0.15,"1/s"]
["R16","RP + G_S -> RP_G_S",0.0028,"1/(nM*s)"]
["R17","G_S -> Grb + SOS",0.0015,"1/s"]
["R18","Grb + SOS -> G_S",0.0001,"1/(nM*s)"]
["R19","RP + Shc -> RP_Sh",0.09,"1/(nM*s)"]
["R20","RP_Sh -> RP + Shc",0.6,"1/s"]
["R21","RP_Sh -> RP_ShP",6,"1/s"]
["R22","RP_ShP -> ShP + RP",0.3,"1/s"]
["R23","ShP + RP -> RP_ShP",0.0009,"1/(nM*s)"]
["R24","RP_ShP + Grb -> RP_ShP_G",0.003,"1/(nM*s)"]
["R25","RP_ShP_G -> RP_ShP + Grb",0.1,"1/s"]
["R26","RP_ShP_G -> RP + ShP_G",0.3,"1/s"]
["R27","RP + ShP_G -> RP_ShP_G",0.0009,"1/(nM*s)"]
["R28","RP_ShP_G + SOS -> RP_ShP_G_S",0.01,"1/(nM*s)"]
["R29","RP_ShP_G_S -> RP_ShP_G + SOS",0.0214,"1/s"]
["R30","RP_ShP_G_S -> ShP_G_S + RP",0.12,"1/s"]
["R31","ShP_G_S + RP -> RP_ShP_G_S",0.00024,"1/(nM*s)"]
["R32","ShP_G + SOS -> ShP_G_S",0.03,"1/(nM*s)"]
["R33","ShP_G_S -> ShP_G + SOS",0.064,"1/s"]
["R34","ShP + Grb -> ShP_G",0.003,"1/(nM*s)"]
["R35","ShP_G -> ShP + Grb",0.1,"1/s"]
["R36","ShP_G_S -> ShP + G_S",0.1,"1/s"]
["R37","ShP + G_S -> ShP_G_S",0.021,"1/(nM*s)"]
["R38","RP_ShP + G_S -> RP_ShP_G_S",0.009,"1/(nM*s)"]
["R39","RP_ShP_G_S -> RP_ShP + G_S",0.0429,"1/s"]
["R40","Ras_GDP -> Ras + GDP",5.4e-06,"1/s"]
["R41","Ras + GDP -> Ras_GDP",0.00027,"1/(nM*s)"]
["R42","Ras + GTP -> Ras_GTP",0.078,"1/(nM*s)"]
["R43","Ras_GTP -> Ras + GTP",0.00078,"1/s"]
["R44","Ras_GTP -> Ras_GDP",1e-05,"1/s"]
["R45","RP_ShP_G_S + Ras_GDP -> RP_ShP_G_S_Ras_GDP",0.00475,"1/(nM*s)"]
["R46","RP_ShP_G_S_Ras_GDP -> RP_ShP_G_S + Ras_GDP",0.76,"1/s"]
["R47","RP_ShP_G_S_Ras_GDP -> RP_ShP_G_S_Ras + GDP",46.5,"1/s"]
["R48","RP_ShP_G_S_Ras + GDP -> RP_ShP_G_S_Ras_GDP",0.093,"1/(nM*s)"]
["R49","RP_ShP_G_S_Ras + GTP -> RP_ShP_G_S_Ras_GTP",0.003,"1/(nM*s)"]
["R50","RP_ShP_G_S_Ras_GTP -> RP_ShP_G_S_Ras + GTP",2.4,"1/s"]
["R51","RP_ShP_G_S_Ras_GTP -> RP_ShP_G_S + Ras_GTP",806.4,"1/s"]
["R52","RP_ShP_G_S + Ras_GTP -> RP_ShP_G_S_Ras_GTP",1.575,"1/(nM*s)"]
["R53","RP_ShP_G_S + Ras -> RP_ShP_G_S_Ras",0.15625,"1/(nM*s)"]
["R54","RP_ShP_G_S_Ras -> RP_ShP_G_S + Ras",0.001,"1/s"]
["R55","RP_G_S + Ras_GDP -> RP_G_S_Ras_GDP",0.0075,"1/(nM*s)"]
["R56","RP_G_S_Ras_GDP -> RP_G_S + Ras_GDP",1.2,"1/s"]
["R57","RP_G_S_Ras_GDP -> RP_G_S_Ras + GDP",50,"1/s"]
["R58","RP_G_S_Ras + GDP -> RP_G_S_Ras_GDP",0.1,"1/(nM*s)"]
["R59","RP_G_S_Ras + GTP -> RP_G_S_Ras_GTP",0.1,"1/(nM*s)"]
["R60","RP_G_S_Ras_GTP -> RP_G_S_Ras + GTP",80,"1/s"]
["R61","RP_G_S_Ras_GTP -> RP_G_S + Ras_GTP",640,"1/s"]
["R62","RP_G_S + Ras_GTP -> RP_G_S_Ras_GTP",1.25,"1/(nM*s)"]
["R63","RP_G_S + Ras -> RP_G_S_Ras",0.25,"1/(nM*s)"]
["R64","RP_G_S_Ras -> RP_G_S + Ras",0.0016,"1/s"]
["R65","Raf + Ras_GTP -> Raf_Ras_GTP",0.01,"1/(nM*s)"]
["R66","Raf_Ras_GTP -> Raf + Ras_GTP",0.0053,"1/s"]
["R67","Raf_Ras_GTP -> [Raf*] + Ras_GTP",1,"1/s"]
["R68","[Raf*] + Pase1 -> [Raf*_Pase1]",0.0717,"1/(nM*s)"]
["R69","[Raf*_Pase1] -> [Raf*] + Pase1",0.2,"1/s"]
["R70","[Raf*_Pase1] -> Raf + Pase1",1,"1/s"]
["R71","MEK + [Raf*] -> [MEK_Raf*]",0.01,"1/(nM*s)"]
["R72","[MEK_Raf*] -> MEK + [Raf*]",0.1,"1/s"]
["R73","[MEK_Raf*] -> [Raf*] + MEKP",1,"1/s"]
["R74","MEKP + [Raf*] -> [MEKP_Raf*]",0.01,"1/(nM*s)"]
["R75","[MEKP_Raf*] -> MEKP + [Raf*]",0.1,"1/s"]
["R76","[MEKP_Raf*] -> MEKPP + [Raf*]",1,"1/s"]
["R77","MEKPP + Pase2 -> MEKPP_Pase2",0.01,"1/(nM*s)"]
["R78","MEKPP_Pase2 -> MEKPP + Pase2",0.1,"1/s"]
["R79","MEKPP_Pase2 -> MEKP + Pase2",0.1,"1/s"]
["R80","MEKP + Pase2 -> MEKP_Pase2",0.01,"1/(nM*s)"]
["R81","MEKP_Pase2 -> MEKP + Pase2",0.1,"1/s"]
["R82","MEKP_Pase2 -> MEK + Pase2",0.1,"1/s"]
["R83","ERK + MEKPP -> ERK_MEKPP",0.01,"1/(nM*s)"]
["R84","ERK_MEKPP -> ERK + MEKPP",0.0033,"1/s"]
["R85","ERK_MEKPP -> ERKP + MEKPP",16,"1/s"]
["R86","ERKP + MEKPP -> ERKP_MEKPP",0.01,"1/(nM*s)"]
["R87","ERKP_MEKPP -> ERKP + MEKPP",0.0033,"1/s"]
["R88","ERKP_MEKPP -> ERKPP + MEKPP",5.7,"1/s"]
["R89","ERKPP + Pase3 -> ERKPP_Pase3",0.0145,"1/(nM*s)"]
["R90","ERKPP_Pase3 -> ERKPP + Pase3",0.6,"1/s"]
["R91","ERKPP_Pase3 -> ERKP + Pase3",0.27,"1/s"]
["R92","ERKP + Pase3 -> ERKP_Pase3",0.05,"1/(nM*s)"]
["R93","ERKP_Pase3 -> ERKP + Pase3",0.5,"1/s"]
["R94","ERKP_Pase3 -> ERK + Pase3",0.3,"1/s"]
["R95","GAP + RP -> RP_GAP",0.083,"1/(nM*s)"]
["R96","RP_GAP -> GAP + RP",0.15,"1/s"]
["R97","Ras_GTP + RP_GAP -> RP_GAP_Ras_GTP",0.01,"1/(nM*s)"]
["R98","RP_GAP_Ras_GTP -> Ras_GTP + RP_GAP",0.03,"1/s"]
["R99","RP_GAP_Ras_GTP -> RP_GAP + Ras_GDP",1.494,"1/s"]
["R100","RP_ShP_G_S + ERKPP -> RP_ShP_G_S_ERKPP",0.01,"1/(nM*s)"]
["R101","RP_ShP_G_S_ERKPP -> RP_ShP_G_S + ERKPP",0.033,"1/s"]
["R102","RP_ShP_G_S_ERKPP -> RP_ShP_G + ERKPP + SOSP",1,"1/s"]
["R103","RP_G_S + ERKPP -> RP_G_S_ERKPP",0.01,"1/(nM*s)"]
["R104","RP_G_S_ERKPP -> RP_G_S + ERKPP",0.033,"1/s"]
["R105","RP_G_S_ERKPP -> RP_G + SOSP + ERKPP",1,"1/s"]
["R106","SOSP + Pase5 -> SOSP_Pase5",0.01,"1/(nM*s)"]
["R107","SOSP_Pase5 -> SOSP + Pase5",0.1,"1/s"]
["R108","SOSP_Pase5 -> SOS + Pase5",1,"1/s"]
["R109","RP_G + GAB -> RP_G_GAB",0.01,"1/(nM*s)"]
["R110","RP_G_GAB -> RP_G + GAB",1,"1/s"]
["R111","RP_ShP_G + GAB -> RP_ShP_G_GAB",0.01,"1/(nM*s)"]
["R112","RP_ShP_G_GAB -> RP_ShP_G + GAB",1,"1/s"]
["R113","RP_G_GAB -> RP_G_GABP",0.05,"1/s"]
["R114","RP_ShP_G_GAB -> RP_ShP_G_GABP",0.05,"1/s"]
["R115","RP_G_GABP + PI3K -> RP_G_GABP_PK",0.01,"1/(nM*s)"]
["R116","RP_G_GABP_PK -> RP_G_GABP + PI3K",1,"1/s"]
["R117","RP_G_GABP_PK -> RP_G_GABP_PKP",1,"1/s"]
["R118","RP_ShP_G_GABP + PI3K -> RP_ShP_G_GABP_PK",0.01,"1/(nM*s)"]
["R119","RP_ShP_G_GABP_PK -> RP_ShP_G_GABP + PI3K",1,"1/s"]
["R120","RP_ShP_G_GABP_PK -> RP_ShP_G_GABP_PKP",1,"1/s"]
["R121","RP_ShP_G_GABP + GAP -> RP_ShP_G_GABP_GAP",0.083,"1/(nM*s)"]
["R122","RP_ShP_G_GABP_GAP -> RP_ShP_G_GABP + GAP",0.15,"1/s"]
["R123","RP_G_GABP + GAP -> RP_G_GABP_GAP",0.083,"1/(nM*s)"]
["R124","RP_G_GABP_GAP -> RP_G_GABP + GAP",0.15,"1/s"]
["R125","RP_G_GABP_GAP + Ras_GTP -> RP_G_GABP_GAP_Ras_GTP",0.6225,"1/(nM*s)"]
["R126","RP_G_GABP_GAP_Ras_GTP -> RP_G_GABP_GAP + Ras_GTP",0.3,"1/s"]
["R127","RP_G_GABP_GAP_Ras_GTP -> RP_G_GABP_GAP + Ras_GDP",1.494,"1/s"]
["R128","RP_ShP_G_GABP_GAP + Ras_GTP -> RP_ShP_G_GABP_GAP_Ras_GTP",0.6225,"1/(nM*s)"]
["R129","RP_ShP_G_GABP_GAP_Ras_GTP -> RP_ShP_G_GABP_GAP + Ras_GTP",0.3,"1/s"]
["R130","RP_ShP_G_GABP_GAP_Ras_GTP -> RP_ShP_G_GABP_GAP + Ras_GDP",1.494,"1/s"]
["R131","RP + PI3K -> RP_PK",0.01,"1/(nM*s)"]
["R132","RP_PK -> RP + PI3K",1,"1/s"]
["R133","RP_PK -> RP_PKP",1,"1/s"]
["R134","RP + PKP -> RP_PKP",0.01,"1/(nM*s)"]
["R135","RP_PKP -> RP + PKP",0.1,"1/s"]
["R136","PIP3 + PTEN -> PIP3_PTEN",0.01,"1/(nM*s)"]
["R137","PIP3_PTEN -> PIP3 + PTEN",0.01,"1/s"]
["R138","PIP3_PTEN -> PIP2 + PTEN",20,"1/s"]
["R139","PKP + PIP2 -> PKP_PIP2",0.01,"1/(nM*s)"]
["R140","PKP_PIP2 -> PKP + PIP2",0.035,"1/s"]
["R141","PKP_PIP2 -> PKP + PIP3",2.5,"1/s"]
["R142","RP_ShP_G_GABP + PhoA -> RP_ShP_G_GABP_PhoA",0.001,"1/(nM*s)"]
["R143","RP_ShP_G_GABP_PhoA -> RP_ShP_G_GABP + PhoA",0.1,"1/s"]
["R144","RP_ShP_G_GABP_PhoA -> RP_ShP_G_GAB + PhoA",0.03,"1/s"]
["R145","RP_G_GABP + PhoA -> RP_G_GABP_PhoA",0.001,"1/(nM*s)"]
["R146","RP_G_GABP_PhoA -> RP_G_GABP + PhoA",0.1,"1/s"]
["R147","RP_G_GABP_PhoA -> RP_G_GAB + PhoA",0.03,"1/s"]
["R148","RP_G_GABP_PKP + PIP2 -> RP_G_GABP_PKP_PIP2",6.25,"1/(nM*s)"]
["R149","RP_G_GABP_PKP_PIP2 -> RP_G_GABP_PKP + PIP2",3.5,"1/s"]
["R150","RP_ShP_G_GABP_PKP + PIP2 -> RP_ShP_G_GABP_PKP_PIP2",6.25,"1/(nM*s)"]
["R151","RP_ShP_G_GABP_PKP_PIP2 -> RP_ShP_G_GABP_PKP + PIP2",3.5,"1/s"]
["R152","RP_G_GABP_PKP_PIP2 -> RP_G_GABP_PKP + PIP3",25,"1/s"]
["R153","RP_ShP_G_GABP_PKP_PIP2 -> RP_ShP_G_GABP_PKP + PIP3",25,"1/s"]
["R154","RP_ShP_G + GABP -> RP_ShP_G_GABP",0.01,"1/(nM*s)"]
["R155","RP_ShP_G_GABP -> RP_ShP_G + GABP",1,"1/s"]
["R156","RP_G + GABP -> RP_G_GABP",0.01,"1/(nM*s)"]
["R157","RP_G_GABP -> RP_G + GABP",1,"1/s"]
["R158","GABP + PhoA -> GABP_PhoA",0.001,"1/(nM*s)"]
["R159","GABP_PhoA -> GABP + PhoA",0.1,"1/s"]
["R160","GABP_PhoA -> GAB + PhoA",0.03,"1/s"]
["R161","AKT + PIP3 -> AKT_PIP3",0.01,"1/(nM*s)"]
["R162","AKT_PIP3 -> AKT + PIP3",10,"1/s"]
["R163","GAB + PIP3 -> GAB_PIP3",0.01,"1/(nM*s)"]
["R164","GAB_PIP3 -> GAB + PIP3",3,"1/s"]
["R165","GABP + PIP3 -> GABP_PIP3",0.01,"1/(nM*s)"]
["R166","GABP_PIP3 -> GABP + PIP3",3,"1/s"]
["R167","RP_G + GAB_PIP3 -> RP_G_GAB_PIP3",2.5,"1/(nM*s)"]
["R168","RP_G_GAB_PIP3 -> RP_G + GAB_PIP3",1,"1/s"]
["R169","RP_ShP_G + GAB_PIP3 -> RP_ShP_G_GAB_PIP3",2.5,"1/(nM*s)"]
["R170","RP_ShP_G_GAB_PIP3 -> RP_ShP_G + GAB_PIP3",1,"1/s"]
["R171","RP_ShP_G_GAB_PIP3 -> RP_ShP_G_GABP + PIP3",0.01,"1/s"]
["R172","AKT_PIP3 + PDK1 -> AKT_PIP3_PDK1",0.01,"1/(nM*s)"]
["R173","AKT_PIP3_PDK1 -> AKT_PIP3 + PDK1",0.1,"1/s"]
["R174","AKT_PIP3_PDK1 -> AKTP + PIP3 + PDK1",5,"1/s"]
["R175","AKTP + TAKT -> AKTP_TAKT",0.01,"1/(nM*s)"]
["R176","AKTP_TAKT -> AKTP + TAKT",1,"1/s"]
["R177","AKTP_TAKT -> AKT + TAKT",1,"1/s"]
["R178","PKP + PhoB -> PKP_PhoB",0.01,"1/(nM*s)"]
["R179","PKP_PhoB -> PKP + PhoB",1,"1/s"]
["R180","PKP_PhoB -> PI3K + PhoB",0.5,"1/s"]
["R181","RP_G_GABP_PKP + PhoB -> RP_G_GABP_PKP_PhoB",0.001,"1/(nM*s)"]
["R182","RP_G_GABP_PKP_PhoB -> RP_G_GABP_PKP + PhoB",0.038,"1/s"]
["R183","RP_G_GABP_PKP_PhoB -> RP_G_GABP_PK + PhoB",0.595,"1/s"]
["R184","RP_ShP_G_GABP_PKP + PhoB -> RP_ShP_G_GABP_PKP_PhoB",0.001,"1/(nM*s)"]
["R185","RP_ShP_G_GABP_PKP_PhoB -> RP_ShP_G_GABP_PKP + PhoB",0.038,"1/s"]
["R186","RP_ShP_G_GABP_PKP_PhoB -> RP_ShP_G_GABP_PK + PhoB",0.595,"1/s"]
["R187","RP_ShP_G_GAB + PIP3 -> RP_ShP_G_GAB_PIP3",2.5,"1/(nM*s)"]
["R188","RP_ShP_G_GAB_PIP3 -> RP_ShP_G_GAB + PIP3",1,"1/s"]
["R189","RP_PKP + PIP2 -> RP_PKP_PIP2",6.25,"1/(nM*s)"]
["R190","RP_PKP_PIP2 -> RP_PKP + PIP2",3.5,"1/s"]
["R191","RP_PKP_PIP2 -> RP_PKP + PIP3",2.5,"1/s"]
["R192","RP_ShP_G_GABP_PKP -> RP_ShP_G_GABP + PKP",5,"1/s"]
["R193","RP_ShP_G_GABP + PKP -> RP_ShP_G_GABP_PKP",0.05,"1/(nM*s)"]
["R194","RP_G_GABP_PKP -> RP_G_GABP + PKP",5,"1/s"]
["R195","RP_G_GABP + PKP -> RP_G_GABP_PKP",0.05,"1/(nM*s)"]
["R196","RP_G_GAB_PIP3 -> RP_G_GABP + PIP3",0.01,"1/s"]
["R197","GSKP + PhoC -> GSKP_PhoC",0.01,"1/(nM*s)"]
["R198","GSKP_PhoC -> GSKP + PhoC",5,"1/s"]
["R199","GSKP_PhoC -> GSK + PhoC",0.1,"1/s"]
["R200","RP_G_GAB + PIP3 -> RP_G_GAB_PIP3",1,"1/(nM*s)"]
["R201","RP_G_GAB_PIP3 -> RP_G_GAB + PIP3",2.5,"1/s"]
["R202","[Raf*] + AKTP -> [Raf*_AKTP]",0.01,"1/(nM*s)"]
["R203","[Raf*_AKTP] -> [Raf*] + AKTP",0.033,"1/s"]
["R204","[Raf*_AKTP] -> [Raf**] + AKTP",5.7,"1/s"]
["R205","[Raf**] + Pase1 -> [Raf**_Pase1]",0.0717,"1/(nM*s)"]
["R206","[Raf**_Pase1] -> [Raf**] + Pase1",0.2,"1/s"]
["R207","[Raf**_Pase1] -> [Raf*] + Pase1",1,"1/s"]
["R208","AKTP + GSK -> AKTP_GSK",0.01,"1/(nM*s)"]
["R209","AKTP_GSK -> AKTP + GSK",0.1,"1/s"]
["R210","AKTP_GSK -> AKTP + GSKP",1,"1/s"]
["R211","R + R -> R_R",0.0001,"1/(nM*s)"]
["R212","R_R -> R + R",0.1,"1/s"]
["R213","EGF + R_R -> Rl_R",0.0001,"1/(nM*s)"]
["R214","Rl_R -> EGF + R_R",1,"1/s"]
["R215","Rl + R -> Rl_R",0.001,"1/(nM*s)"]
["R216","Rl_R -> Rl + R",0.1,"1/s"]
["R217","Rl_R -> RlP_RP",1,"1/s"]
["R218","RlP_RP -> EGF + RP_RP",0.1,"1/s"]
["R219","EGF + RP_RP -> RlP_RP",0.01,"1/(nM*s)"]
["R220","RP_RP -> RP + RP",0.1,"1/s"]
["R221","RP + RP -> RP_RP",0.01,"1/(nM*s)"]
["R222","RP_R -> RP_RP",1,"1/s"]
["R223","RP + R -> RP_R",0.001,"1/(nM*s)"]
["R224","RP_R -> RP + R",0.1,"1/s"]
["R225","CDC25CP + RP -> CDC25CP_RP",0.01,"1/(nM*s)"]
["R226","CDC25CP_RP -> CDC25CP + RP",0.1,"1/s"]
["R227","CDC25CP_RP -> CDC25CP + R",1,"1/s"]
["R228","CDC25CP + RP_RP -> CDC25CP_RP_RP",0.01,"1/(nM*s)"]
["R229","CDC25CP_RP_RP -> CDC25CP + RP_RP",0.1,"1/s"]
["R230","CDC25CP_RP_RP -> CDC25CP + R_R",0.5,"1/s"]
["R231","R + ERB -> R_ERB",0.001,"1/(nM*s)"]
["R232","R_ERB -> R + ERB",0.1,"1/s"]
["R233","R_ERB + EGF -> Rl_ERB",0.01,"1/(nM*s)"]
["R234","Rl_ERB -> R_ERB + EGF",0.1,"1/s"]
["R235","Rl_ERB -> RlP_ERBP",1,"1/s"]
["R236","RlP_ERBP -> EGF + RP_ERBP",0.1,"1/s"]
["R237","EGF + RP_ERBP -> RlP_ERBP",0.01,"1/(nM*s)"]
["R238","RP_ERBP -> RP + ERBP",0.1,"1/s"]
["R239","RP + ERBP -> RP_ERBP",0.01,"1/(nM*s)"]
["R240","Rl + ERB -> Rl_ERB",0.01,"1/(nM*s)"]
["R241","Rl_ERB -> Rl + ERB",0.1,"1/s"]
["R242","R + ERBP -> R_ERBP",0.001,"1/(nM*s)"]
["R243","R_ERBP -> R + ERBP",0.1,"1/s"]
["R244","R_ERBP -> RP_ERBP",1,"1/s"]
["R245","RlP_ERBP -> RlP + ERBP",0.1,"1/s"]
["R246","RlP + ERBP -> RlP_ERBP",0.01,"1/(nM*s)"]
["R247","RP + ERB -> RP_ERB",0.01,"1/(nM*s)"]
["R248","RP_ERB -> RP + ERB",0.1,"1/s"]
["R249","RP_ERB -> RP_ERBP",1,"1/s"]
["R250","ERBP + ERB -> ERBP_ERB",0.01,"1/(nM*s)"]
["R251","ERBP_ERB -> ERBP + ERB",0.1,"1/s"]
["R252","ERBP_ERBP -> ERBP + ERBP",0.1,"1/s"]
["R253","ERBP + ERBP -> ERBP_ERBP",0.01,"1/(nM*s)"]
["R254","ERB + ERB -> ERB_ERB",0.01,"1/(nM*s)"]
["R255","ERB_ERB -> ERB + ERB",0.1,"1/s"]
["R256","ERBP_ERB -> ERBP_ERBP",1,"1/s"]
["R257","CDC25CP + ERBP -> CDC25CP_ERBP",0.01,"1/(nM*s)"]
["R258","CDC25CP_ERBP -> CDC25CP + ERBP",0.1,"1/s"]
["R259","CDC25CP_ERBP -> CDC25CP + ERB",0.5,"1/s"]
["R260","ShP + PTP1E -> PTP1E_ShP",0.01,"1/(nM*s)"]
["R261","PTP1E_ShP -> ShP + PTP1E",0.1,"1/s"]
["R262","PTP1E_ShP -> PTP1E + Shc",0.005,"1/s"]
["R263","PLCyP + PaseX -> PLCyP_PaseX",0.01,"1/(nM*s)"]
["R264","PLCyP_PaseX -> PLCyP + PaseX",0.1,"1/s"]
["R265","PLCyP_PaseX -> PLCy + PaseX",0.01,"1/s"]
["R266","Rl2P -> RlP + RlP",0.1,"1/s"]
["R267","RlP + RlP -> Rl2P",0.01,"1/(nM*s)"]
["R268","RlP -> EGF + RP",0.1,"1/s"]
["R269","EGF + RP -> RlP",0.01,"1/(nM*s)"]
["R270","CDC25CP + ERBP_ERBP -> CDC25CP_ERBP_ERBP",0.01,"1/(nM*s)"]
["R271","CDC25CP_ERBP_ERBP -> CDC25CP + ERBP_ERBP",0.1,"1/s"]
["R272","CDC25CP_ERBP_ERBP -> CDC25CP + ERB_ERB",0.5,"1/s"]
["R273","ERBP + PLCy -> ERBP_PL",0.06,"1/(nM*s)"]
["R274","ERBP_PL -> ERBP + PLCy",0.2,"1/s"]
["R275","ERBP_PL -> ERBP_PLP",1,"1/s"]
["R276","ERBP_PLP -> ERBP + PLCyP",0.3,"1/s"]
["R277","ERBP + PLCyP -> ERBP_PLP",0.006,"1/(nM*s)"]
["R278","ERBP + Grb -> ERBP_G",0.0015,"1/(nM*s)"]
["R279","ERBP_G -> ERBP + Grb",0.2,"1/s"]
["R280","ERBP_G + SOS -> ERBP_G_S",0.01,"1/(nM*s)"]
["R281","ERBP_G_S -> ERBP_G + SOS",0.06,"1/s"]
["R282","ERBP_G_S -> ERBP + G_S",0.15,"1/s"]
["R283","ERBP + G_S -> ERBP_G_S",0.0028,"1/(nM*s)"]
["R284","ERBP + Shc -> ERBP_Sh",0.09,"1/(nM*s)"]
["R285","ERBP_Sh -> ERBP + Shc",0.6,"1/s"]
["R286","ERBP_Sh -> ERBP_ShP",6,"1/s"]
["R287","ERBP_ShP -> ShP + ERBP",0.3,"1/s"]
["R288","ShP + ERBP -> ERBP_ShP",0.0009,"1/(nM*s)"]
["R289","ERBP_ShP + Grb -> ERBP_ShP_G",0.003,"1/(nM*s)"]
["R290","ERBP_ShP_G -> ERBP_ShP + Grb",0.1,"1/s"]
["R291","ERBP_ShP_G -> ERBP + ShP_G",0.3,"1/s"]
["R292","ERBP + ShP_G -> ERBP_ShP_G",0.0009,"1/(nM*s)"]
["R293","ERBP_ShP_G + SOS -> ERBP_ShP_G_S",0.01,"1/(nM*s)"]
["R294","ERBP_ShP_G_S -> ERBP_ShP_G + SOS",0.0214,"1/s"]
["R295","ERBP_ShP_G_S -> ShP_G_S + ERBP",0.12,"1/s"]
["R296","ShP_G_S + ERBP -> ERBP_ShP_G_S",0.00024,"1/(nM*s)"]
["R297","ERBP_ShP + G_S -> ERBP_ShP_G_S",0.009,"1/(nM*s)"]
["R298","ERBP_ShP_G_S -> ERBP_ShP + G_S",0.0429,"1/s"]
["R299","ERBP_ShP_G_S + Ras_GDP -> ERBP_ShP_G_S_Ras_GDP",0.00475,"1/(nM*s)"]
["R300","ERBP_ShP_G_S_Ras_GDP -> ERBP_ShP_G_S + Ras_GDP",0.76,"1/s"]
["R301","ERBP_ShP_G_S_Ras_GDP -> ERBP_ShP_G_S_Ras + GDP",46.5,"1/s"]
["R302","ERBP_ShP_G_S_Ras + GDP -> ERBP_ShP_G_S_Ras_GDP",0.093,"1/(nM*s)"]
["R303","ERBP_ShP_G_S_Ras + GTP -> ERBP_ShP_G_S_Ras_GTP",0.003,"1/(nM*s)"]
["R304","ERBP_ShP_G_S_Ras_GTP -> ERBP_ShP_G_S_Ras + GTP",2.4,"1/s"]
["R305","ERBP_ShP_G_S_Ras_GTP -> ERBP_ShP_G_S + Ras_GTP",806.4,"1/s"]
["R306","ERBP_ShP_G_S + Ras_GTP -> ERBP_ShP_G_S_Ras_GTP",1.575,"1/(nM*s)"]
["R307","ERBP_ShP_G_S + Ras -> ERBP_ShP_G_S_Ras",0.15625,"1/(nM*s)"]
["R308","ERBP_ShP_G_S_Ras -> ERBP_ShP_G_S + Ras",0.001,"1/s"]
["R309","ERBP_G_S + Ras_GDP -> ERBP_G_S_Ras_GDP",0.0075,"1/(nM*s)"]
["R310","ERBP_G_S_Ras_GDP -> ERBP_G_S + Ras_GDP",1.2,"1/s"]
["R311","ERBP_G_S_Ras_GDP -> ERBP_G_S_Ras + GDP",50,"1/s"]
["R312","ERBP_G_S_Ras + GDP -> ERBP_G_S_Ras_GDP",0.1,"1/(nM*s)"]
["R313","ERBP_G_S_Ras + GTP -> ERBP_G_S_Ras_GTP",0.1,"1/(nM*s)"]
["R314","ERBP_G_S_Ras_GTP -> ERBP_G_S_Ras + GTP",80,"1/s"]
["R315","ERBP_G_S_Ras_GTP -> ERBP_G_S + Ras_GTP",640,"1/s"]
["R316","ERBP_G_S + Ras_GTP -> ERBP_G_S_Ras_GTP",1.25,"1/(nM*s)"]
["R317","ERBP_G_S + Ras -> ERBP_G_S_Ras",0.25,"1/(nM*s)"]
["R318","ERBP_G_S_Ras -> ERBP_G_S + Ras",0.0016,"1/s"]
["R319","GAP + ERBP -> ERBP_GAP",0.083,"1/(nM*s)"]
["R320","ERBP_GAP -> GAP + ERBP",0.15,"1/s"]
["R321","Ras_GTP + ERBP_GAP -> ERBP_GAP_Ras_GTP",0.01,"1/(nM*s)"]
["R322","ERBP_GAP_Ras_GTP -> Ras_GTP + ERBP_GAP",0.03,"1/s"]
["R323","ERBP_GAP_Ras_GTP -> ERBP_GAP + Ras_GDP",1.494,"1/s"]
["R324","ERBP_ShP_G_S + ERKPP -> ERBP_ShP_G_S_ERKPP",0.01,"1/(nM*s)"]
["R325","ERBP_ShP_G_S_ERKPP -> ERBP_ShP_G_S + ERKPP",0.033,"1/s"]
["R326","ERBP_ShP_G_S_ERKPP -> ERBP_ShP_G + ERKPP + SOSP",1,"1/s"]
["R327","ERBP_G_S + ERKPP -> ERBP_G_S_ERKPP",0.01,"1/(nM*s)"]
["R328","ERBP_G_S_ERKPP -> ERBP_G_S + ERKPP",0.033,"1/s"]
["R329","ERBP_G_S_ERKPP -> ERBP_G + SOSP + ERKPP",1,"1/s"]
["R330","ERBP_G + GAB -> ERBP_G_GAB",0.01,"1/(nM*s)"]
["R331","ERBP_G_GAB -> ERBP_G + GAB",1,"1/s"]
["R332","ERBP_ShP_G + GAB -> ERBP_ShP_G_GAB",0.01,"1/(nM*s)"]
["R333","ERBP_ShP_G_GAB -> ERBP_ShP_G + GAB",1,"1/s"]
["R334","ERBP_G_GAB -> ERBP_G_GABP",0.05,"1/s"]
["R335","ERBP_ShP_G_GAB -> ERBP_ShP_G_GABP",0.05,"1/s"]
["R336","ERBP_G_GABP + PI3K -> ERBP_G_GABP_PK",0.01,"1/(nM*s)"]
["R337","ERBP_G_GABP_PK -> ERBP_G_GABP + PI3K",1,"1/s"]
["R338","ERBP_G_GABP_PK -> ERBP_G_GABP_PKP",1,"1/s"]
["R339","ERBP_ShP_G_GABP + PI3K -> ERBP_ShP_G_GABP_PK",0.01,"1/(nM*s)"]
["R340","ERBP_ShP_G_GABP_PK -> ERBP_ShP_G_GABP + PI3K",1,"1/s"]
["R341","ERBP_ShP_G_GABP_PK -> ERBP_ShP_G_GABP_PKP",1,"1/s"]
["R342","ERBP_ShP_G_GABP + GAP -> ERBP_ShP_G_GABP_GAP",0.083,"1/(nM*s)"]
["R343","ERBP_ShP_G_GABP_GAP -> ERBP_ShP_G_GABP + GAP",0.15,"1/s"]
["R344","ERBP_G_GABP + GAP -> ERBP_G_GABP_GAP",0.083,"1/(nM*s)"]
["R345","ERBP_G_GABP_GAP -> ERBP_G_GABP + GAP",0.15,"1/s"]
["R346","ERBP_G_GABP_GAP + Ras_GTP -> ERBP_G_GABP_GAP_Ras_GTP",0.6225,"1/(nM*s)"]
["R347","ERBP_G_GABP_GAP_Ras_GTP -> ERBP_G_GABP_GAP + Ras_GTP",0.3,"1/s"]
["R348","ERBP_G_GABP_GAP_Ras_GTP -> ERBP_G_GABP_GAP + Ras_GDP",1.494,"1/s"]
["R349","ERBP_ShP_G_GABP_GAP + Ras_GTP -> ERBP_ShP_G_GABP_GAP_Ras_GTP",0.6225,"1/(nM*s)"]
["R350","ERBP_ShP_G_GABP_GAP_Ras_GTP -> ERBP_ShP_G_GABP_GAP + Ras_GTP",0.3,"1/s"]
["R351","ERBP_ShP_G_GABP_GAP_Ras_GTP -> ERBP_ShP_G_GABP_GAP + Ras_GDP",1.494,"1/s"]
["R352","ERBP + PI3K -> ERBP_PK",0.01,"1/(nM*s)"]
["R353","ERBP_PK -> ERBP + PI3K",1,"1/s"]
["R354","ERBP_PK -> ERBP_PKP",1,"1/s"]
["R355","ERBP + PKP -> ERBP_PKP",0.01,"1/(nM*s)"]
["R356","ERBP_PKP -> ERBP + PKP",0.1,"1/s"]
["R357","ERBP_ShP_G_GABP + PhoA -> ERBP_ShP_G_GABP_PhoA",0.001,"1/(nM*s)"]
["R358","ERBP_ShP_G_GABP_PhoA -> ERBP_ShP_G_GABP + PhoA",0.1,"1/s"]
["R359","ERBP_ShP_G_GABP_PhoA -> ERBP_ShP_G_GAB + PhoA",0.03,"1/s"]
["R360","ERBP_G_GABP + PhoA -> ERBP_G_GABP_PhoA",0.001,"1/(nM*s)"]
["R361","ERBP_G_GABP_PhoA -> ERBP_G_GABP + PhoA",0.1,"1/s"]
["R362","ERBP_G_GABP_PhoA -> ERBP_G_GAB + PhoA",0.03,"1/s"]
["R363","ERBP_G_GABP_PKP + PIP2 -> ERBP_G_GABP_PKP_PIP2",6.25,"1/(nM*s)"]
["R364","ERBP_G_GABP_PKP_PIP2 -> ERBP_G_GABP_PKP + PIP2",3.5,"1/s"]
["R365","ERBP_ShP_G_GABP_PKP + PIP2 -> ERBP_ShP_G_GABP_PKP_PIP2",6.25,"1/(nM*s)"]
["R366","ERBP_ShP_G_GABP_PKP_PIP2 -> ERBP_ShP_G_GABP_PKP + PIP2",3.5,"1/s"]
["R367","ERBP_G_GABP_PKP_PIP2 -> ERBP_G_GABP_PKP + PIP3",25,"1/s"]
["R368","ERBP_ShP_G_GABP_PKP_PIP2 -> ERBP_ShP_G_GABP_PKP + PIP3",25,"1/s"]
["R369","ERBP_G_GABP_PKP + PIP3 -> ERBP_G_GABP_PKP_PIP3",25,"1/(nM*s)"]
["R370","ERBP_G_GABP_PKP_PIP3 -> ERBP_G_GABP_PKP + PIP3",3,"1/s"]
["R371","ERBP_ShP_G_GABP_PKP + PIP3 -> ERBP_ShP_G_GABP_PKP_PIP3",25,"1/(nM*s)"]
["R372","ERBP_ShP_G_GABP_PKP_PIP3 -> ERBP_ShP_G_GABP_PKP + PIP3",3,"1/s"]
["R373","ERBP_ShP_G + GABP -> ERBP_ShP_G_GABP",0.01,"1/(nM*s)"]
["R374","ERBP_ShP_G_GABP -> ERBP_ShP_G + GABP",1,"1/s"]
["R375","ERBP_G + GABP -> ERBP_G_GABP",0.01,"1/(nM*s)"]
["R376","ERBP_G_GABP -> ERBP_G + GABP",1,"1/s"]
["R377","ERBP_G + GAB_PIP3 -> ERBP_G_GAB_PIP3",2.5,"1/(nM*s)"]
["R378","ERBP_G_GAB_PIP3 -> ERBP_G + GAB_PIP3",1,"1/s"]
["R379","ERBP_ShP_G + GAB_PIP3 -> ERBP_ShP_G_GAB_PIP3",2.5,"1/(nM*s)"]
["R380","ERBP_ShP_G_GAB_PIP3 -> ERBP_ShP_G + GAB_PIP3",1,"1/s"]
["R381","ERBP_ShP_G_GAB_PIP3 -> ERBP_ShP_G_GABP + PIP3",0.01,"1/s"]
["R382","ERBP_G_GABP_PKP + PhoB -> ERBP_G_GABP_PKP_PhoB",0.001,"1/(nM*s)"]
["R383","ERBP_G_GABP_PKP_PhoB -> ERBP_G_GABP_PKP + PhoB",0.038,"1/s"]
["R384","ERBP_G_GABP_PKP_PhoB -> ERBP_G_GABP_PK + PhoB",0.595,"1/s"]
["R385","ERBP_ShP_G_GABP_PKP + PhoB -> ERBP_ShP_G_GABP_PKP_PhoB",0.001,"1/(nM*s)"]
["R386","ERBP_ShP_G_GABP_PKP_PhoB -> ERBP_ShP_G_GABP_PKP + PhoB",0.038,"1/s"]
["R387","ERBP_ShP_G_GABP_PKP_PhoB -> ERBP_ShP_G_GABP_PK + PhoB",0.595,"1/s"]
["R388","ERBP_ShP_G_GAB + PIP3 -> ERBP_ShP_G_GAB_PIP3",2.5,"1/(nM*s)"]
["R389","ERBP_ShP_G_GAB_PIP3 -> ERBP_ShP_G_GAB + PIP3",1,"1/s"]
["R390","ERBP_PKP + PIP2 -> ERBP_PKP_PIP2",6.25,"1/(nM*s)"]
["R391","ERBP_PKP_PIP2 -> ERBP_PKP + PIP2",3.5,"1/s"]
["R392","ERBP_PKP_PIP2 -> ERBP_PKP + PIP3",2.5,"1/s"]
["R393","ERBP_ShP_G_GABP_PKP -> ERBP_ShP_G_GABP + PKP",5,"1/s"]
["R394","ERBP_ShP_G_GABP + PKP -> ERBP_ShP_G_GABP_PKP",0.05,"1/(nM*s)"]
["R395","ERBP_G_GABP_PKP -> ERBP_G_GABP + PKP",5,"1/s"]
["R396","ERBP_G_GABP + PKP -> ERBP_G_GABP_PKP",0.05,"1/(nM*s)"]
["R397","ERBP_G_GAB_PIP3 -> ERBP_G_GABP + PIP3",0.01,"1/s"]
["R398","ERBP_G_GAB + PIP3 -> ERBP_G_GAB_PIP3",1,"1/(nM*s)"]
["R399","ERBP_G_GAB_PIP3 -> ERBP_G_GAB + PIP3",2.5,"1/s"]
["R400","ERB3P + PLCy -> ERB3P_PL",0.06,"1/(nM*s)"]
["R401","ERB3P_PL -> ERB3P + PLCy",0.2,"1/s"]
["R402","ERB3P_PL -> ERB3P_PLP",1,"1/s"]
["R403","ERB3P_PLP -> ERB3P + PLCyP",0.3,"1/s"]
["R404","ERB3P + PLCyP -> ERB3P_PLP",0.006,"1/(nM*s)"]
["R405","ERB3P + Grb -> ERB3P_G",0.0015,"1/(nM*s)"]
["R406","ERB3P_G -> ERB3P + Grb",0.2,"1/s"]
["R407","ERB3P_G + SOS -> ERB3P_G_S",0.01,"1/(nM*s)"]
["R408","ERB3P_G_S -> ERB3P_G + SOS",0.06,"1/s"]
["R409","ERB3P_G_S -> ERB3P + G_S",0.15,"1/s"]
["R410","ERB3P + G_S -> ERB3P_G_S",0.0028,"1/(nM*s)"]
["R411","ERB3P + Shc -> ERB3P_Sh",0.09,"1/(nM*s)"]
["R412","ERB3P_Sh -> ERB3P + Shc",0.6,"1/s"]
["R413","ERB3P_Sh -> ERB3P_ShP",6,"1/s"]
["R414","ERB3P_ShP -> ShP + ERB3P",0.3,"1/s"]
["R415","ShP + ERB3P -> ERB3P_ShP",0.0009,"1/(nM*s)"]
["R416","ERB3P_ShP + Grb -> ERB3P_ShP_G",0.003,"1/(nM*s)"]
["R417","ERB3P_ShP_G -> ERB3P_ShP + Grb",0.1,"1/s"]
["R418","ERB3P_ShP_G -> ERB3P + ShP_G",0.3,"1/s"]
["R419","ERB3P + ShP_G -> ERB3P_ShP_G",0.0009,"1/(nM*s)"]
["R420","ERB3P_ShP_G + SOS -> ERB3P_ShP_G_S",0.01,"1/(nM*s)"]
["R421","ERB3P_ShP_G_S -> ERB3P_ShP_G + SOS",0.0214,"1/s"]
["R422","ERB3P_ShP_G_S -> ShP_G_S + ERB3P",0.12,"1/s"]
["R423","ShP_G_S + ERB3P -> ERB3P_ShP_G_S",0.00024,"1/(nM*s)"]
["R424","ERB3P_ShP + G_S -> ERB3P_ShP_G_S",0.009,"1/(nM*s)"]
["R425","ERB3P_ShP_G_S -> ERB3P_ShP + G_S",0.0429,"1/s"]
["R426","ERB3P_ShP_G_S + Ras_GDP -> ERB3P_Sh_G_S_Ras_GDP",0.00475,"1/(nM*s)"]
["R427","ERB3P_Sh_G_S_Ras_GDP -> ERB3P_ShP_G_S + Ras_GDP",0.76,"1/s"]
["R428","ERB3P_Sh_G_S_Ras_GDP -> ERB3P_Sh_G_S_Ras + GDP",46.5,"1/s"]
["R429","ERB3P_Sh_G_S_Ras + GDP -> ERB3P_Sh_G_S_Ras_GDP",0.093,"1/(nM*s)"]
["R430","ERB3P_Sh_G_S_Ras + GTP -> ERB3P_Sh_G_S_Ras_GTP",0.003,"1/(nM*s)"]
["R431","ERB3P_Sh_G_S_Ras_GTP -> ERB3P_Sh_G_S_Ras + GTP",2.4,"1/s"]
["R432","ERB3P_Sh_G_S_Ras_GTP -> ERB3P_ShP_G_S + Ras_GTP",806.4,"1/s"]
["R433","ERB3P_ShP_G_S + Ras_GTP -> ERB3P_Sh_G_S_Ras_GTP",1.575,"1/(nM*s)"]
["R434","ERB3P_ShP_G_S + Ras -> ERB3P_Sh_G_S_Ras",0.15625,"1/(nM*s)"]
["R435","ERB3P_Sh_G_S_Ras -> ERB3P_ShP_G_S + Ras",0.001,"1/s"]
["R436","ERB3P_G_S + Ras_GDP -> ERB3P_G_S_Ras_GDP",0.0075,"1/(nM*s)"]
["R437","ERB3P_G_S_Ras_GDP -> ERB3P_G_S + Ras_GDP",1.2,"1/s"]
["R438","ERB3P_G_S_Ras_GDP -> ERB3P_G_S_Ras + GDP",50,"1/s"]
["R439","ERB3P_G_S_Ras + GDP -> ERB3P_G_S_Ras_GDP",0.1,"1/(nM*s)"]
["R440","ERB3P_G_S_Ras + GTP -> ERB3P_G_S_Ras_GTP",0.1,"1/(nM*s)"]
["R441","ERB3P_G_S_Ras_GTP -> ERB3P_G_S_Ras + GTP",80,"1/s"]
["R442","ERB3P_G_S_Ras_GTP -> ERB3P_G_S + Ras_GTP",640,"1/s"]
["R443","ERB3P_G_S + Ras_GTP -> ERB3P_G_S_Ras_GTP",1.25,"1/(nM*s)"]
["R444","ERB3P_G_S + Ras -> ERB3P_G_S_Ras",0.25,"1/(nM*s)"]
["R445","ERB3P_G_S_Ras -> ERB3P_G_S + Ras",0.0016,"1/s"]
["R446","GAP + ERB3P -> ERB3P_GAP",0.083,"1/(nM*s)"]
["R447","ERB3P_GAP -> GAP + ERB3P",0.15,"1/s"]
["R448","Ras_GTP + ERB3P_GAP -> ERB3P_GAP_Ras_GTP",0.01,"1/(nM*s)"]
["R449","ERB3P_GAP_Ras_GTP -> Ras_GTP + ERB3P_GAP",0.03,"1/s"]
["R450","ERB3P_GAP_Ras_GTP -> ERB3P_GAP + Ras_GDP",1.494,"1/s"]
["R451","ERB3P_ShP_G_S + ERKPP -> ERB3P_Sh_G_S_ERKPP",0.01,"1/(nM*s)"]
["R452","ERB3P_Sh_G_S_ERKPP -> ERB3P_ShP_G_S + ERKPP",0.033,"1/s"]
["R453","ERB3P_Sh_G_S_ERKPP -> ERB3P_ShP_G + ERKPP + SOSP",1,"1/s"]
["R454","ERB3P_G_S + ERKPP -> ERB3P_G_S_ERKPP",0.01,"1/(nM*s)"]
["R455","ERB3P_G_S_ERKPP -> ERB3P_G_S + ERKPP",0.033,"1/s"]
["R456","ERB3P_G_S_ERKPP -> ERB3P_G + SOSP + ERKPP",1,"1/s"]
["R457","ERB3P_G + GAB -> ERB3P_G_GAB",0.01,"1/(nM*s)"]
["R458","ERB3P_G_GAB -> ERB3P_G + GAB",1,"1/s"]
["R459","ERB3P_ShP_G + GAB -> ERB3P_ShP_G_GAB",0.01,"1/(nM*s)"]
["R460","ERB3P_ShP_G_GAB -> ERB3P_ShP_G + GAB",1,"1/s"]
["R461","ERB3P_G_GAB -> ERB3P_G_GABP",0.05,"1/s"]
["R462","ERB3P_ShP_G_GAB -> ERB3P_ShP_G_GABP",0.05,"1/s"]
["R463","ERB3P_G_GABP + PI3K -> ERB3P_G_GABP_PK",0.01,"1/(nM*s)"]
["R464","ERB3P_G_GABP_PK -> ERB3P_G_GABP + PI3K",1,"1/s"]
["R465","ERB3P_G_GABP_PK -> ERB3P_G_GABP_PKP",1,"1/s"]
["R466","ERB3P_ShP_G_GABP + PI3K -> ERB3P_ShP_G_GABP_PK",0.01,"1/(nM*s)"]
["R467","ERB3P_ShP_G_GABP_PK -> ERB3P_ShP_G_GABP + PI3K",1,"1/s"]
["R468","ERB3P_ShP_G_GABP_PK -> ERB3P_ShP_G_GABP_PKP",1,"1/s"]
["R469","ERB3P_ShP_G_GABP + GAP -> ERB3P_ShP_G_GABP_GAP",0.083,"1/(nM*s)"]
["R470","ERB3P_ShP_G_GABP_GAP -> ERB3P_ShP_G_GABP + GAP",0.15,"1/s"]
["R471","ERB3P_G_GABP + GAP -> ERB3P_G_GABP_GAP",0.083,"1/(nM*s)"]
["R472","ERB3P_G_GABP_GAP -> ERB3P_G_GABP + GAP",0.15,"1/s"]
["R473","ERB3P_G_GABP_GAP + Ras_GTP -> ERB3P_G_GABP_GAP_Ras_GTP",0.6225,"1/(nM*s)"]
["R474","ERB3P_G_GABP_GAP_Ras_GTP -> ERB3P_G_GABP_GAP + Ras_GTP",0.3,"1/s"]
["R475","ERB3P_G_GABP_GAP_Ras_GTP -> ERB3P_G_GABP_GAP + Ras_GDP",1.494,"1/s"]
["R476","ERB3P_ShP_G_GABP_GAP + Ras_GTP -> ERB3P_ShP_G_GABP_GAP_Ras_GTP",0.6225,"1/(nM*s)"]
["R477","ERB3P_ShP_G_GABP_GAP_Ras_GTP -> ERB3P_ShP_G_GABP_GAP + Ras_GTP",0.3,"1/s"]
["R478","ERB3P_ShP_G_GABP_GAP_Ras_GTP -> ERB3P_ShP_G_GABP_GAP + Ras_GDP",1.494,"1/s"]
["R479","ERB3P + PI3K -> ERB3P_PK",0.01,"1/(nM*s)"]
["R480","ERB3P_PK -> ERB3P + PI3K",1,"1/s"]
["R481","ERB3P_PK -> ERB3P_PKP",1,"1/s"]
["R482","ERB3P + PKP -> ERB3P_PKP",0.01,"1/(nM*s)"]
["R483","ERB3P_PKP -> ERB3P + PKP",0.1,"1/s"]
["R484","ERB3P_ShP_G_GABP + PhoA -> ERB3P_ShP_G_GABP_PhoA",0.001,"1/(nM*s)"]
["R485","ERB3P_ShP_G_GABP_PhoA -> ERB3P_ShP_G_GABP + PhoA",0.1,"1/s"]
["R486","ERB3P_ShP_G_GABP_PhoA -> ERB3P_ShP_G_GAB + PhoA",0.03,"1/s"]
["R487","ERB3P_G_GABP + PhoA -> ERB3P_G_GABP_PhoA",0.001,"1/(nM*s)"]
["R488","ERB3P_G_GABP_PhoA -> ERB3P_G_GABP + PhoA",0.1,"1/s"]
["R489","ERB3P_G_GABP_PhoA -> ERB3P_G_GAB + PhoA",0.03,"1/s"]
["R490","ERB3P_G_GABP_PKP + PIP2 -> ERB3P_G_GABP_PKP_PIP2",6.25,"1/(nM*s)"]
["R491","ERB3P_G_GABP_PKP_PIP2 -> ERB3P_G_GABP_PKP + PIP2",3.5,"1/s"]
["R492","ERB3P_ShP_G_GABP_PKP + PIP2 -> ERB3P_ShP_G_GABP_PKP_PIP2",6.25,"1/(nM*s)"]
["R493","ERB3P_ShP_G_GABP_PKP_PIP2 -> ERB3P_ShP_G_GABP_PKP + PIP2",3.5,"1/s"]
["R494","ERB3P_G_GABP_PKP_PIP2 -> ERB3P_G_GABP_PKP + PIP3",25,"1/s"]
["R495","ERB3P_ShP_G_GABP_PKP_PIP2 -> ERB3P_ShP_G_GABP_PKP + PIP3",25,"1/s"]
["R496","ERB3P_ShP_G + GABP -> ERB3P_ShP_G_GABP",0.01,"1/(nM*s)"]
["R497","ERB3P_ShP_G_GABP -> ERB3P_ShP_G + GABP",1,"1/s"]
["R498","ERB3P_G + GABP -> ERB3P_G_GABP",0.01,"1/(nM*s)"]
["R499","ERB3P_G_GABP -> ERB3P_G + GABP",1,"1/s"]
["R500","ERB3P_G + GAB_PIP3 -> ERB3P_G_GAB_PIP3",2.5,"1/(nM*s)"]
["R501","ERB3P_G_GAB_PIP3 -> ERB3P_G + GAB_PIP3",1,"1/s"]
["R502","ERB3P_ShP_G + GAB_PIP3 -> ERB3P_ShP_G_GAB_PIP3",2.5,"1/(nM*s)"]
["R503","ERB3P_ShP_G_GAB_PIP3 -> ERB3P_ShP_G + GAB_PIP3",1,"1/s"]
["R504","ERB3P_ShP_G_GAB_PIP3 -> ERB3P_ShP_G_GABP + PIP3",0.01,"1/s"]
["R505","ERB3P_G_GABP_PKP + PhoB -> ERB3P_G_GABP_PKP_PhoB",0.001,"1/(nM*s)"]
["R506","ERB3P_G_GABP_PKP_PhoB -> ERB3P_G_GABP_PKP + PhoB",0.038,"1/s"]
["R507","ERB3P_G_GABP_PKP_PhoB -> ERB3P_G_GABP_PK + PhoB",0.595,"1/s"]
["R508","ERB3P_ShP_G_GABP_PKP + PhoB -> ERB3P_ShP_G_GABP_PKP_PhoB",0.001,"1/(nM*s)"]
["R509","ERB3P_ShP_G_GABP_PKP_PhoB -> ERB3P_ShP_G_GABP_PKP + PhoB",0.038,"1/s"]
["R510","ERB3P_ShP_G_GABP_PKP_PhoB -> ERB3P_ShP_G_GABP_PK + PhoB",0.595,"1/s"]
["R511","ERB3P_ShP_G_GAB + PIP3 -> ERB3P_ShP_G_GAB_PIP3",2.5,"1/(nM*s)"]
["R512","ERB3P_ShP_G_GAB_PIP3 -> ERB3P_ShP_G_GAB + PIP3",1,"1/s"]
["R513","ERB3P_PKP + PIP2 -> ERB3P_PKP_PIP2",6.25,"1/(nM*s)"]
["R514","ERB3P_PKP_PIP2 -> ERB3P_PKP + PIP2",3.5,"1/s"]
["R515","ERB3P_PKP_PIP2 -> ERB3P_PKP + PIP3",2.5,"1/s"]
["R516","ERB3P_ShP_G_GABP_PKP -> ERB3P_ShP_G_GABP + PKP",5,"1/s"]
["R517","ERB3P_ShP_G_GABP + PKP -> ERB3P_ShP_G_GABP_PKP",0.05,"1/(nM*s)"]
["R518","ERB3P_G_GABP_PKP -> ERB3P_G_GABP + PKP",5,"1/s"]
["R519","ERB3P_G_GABP + PKP -> ERB3P_G_GABP_PKP",0.05,"1/(nM*s)"]
["R520","ERB3P_G_GAB_PIP3 -> ERB3P_G_GABP + PIP3",0.01,"1/s"]
["R521","ERB3P_G_GAB + PIP3 -> ERB3P_G_GAB_PIP3",1,"1/(nM*s)"]
["R522","ERB3P_G_GAB_PIP3 -> ERB3P_G_GAB + PIP3",2.5,"1/s"]
["R523","R + ERB3 -> R_ERB3",0.0001,"1/(nM*s)"]
["R524","R_ERB3 -> R + ERB3",0.1,"1/s"]
["R525","EGF + R_ERB3 -> Rl_ERB3",0.0001,"1/(nM*s)"]
["R526","Rl_ERB3 -> EGF + R_ERB3",0.1,"1/s"]
["R527","Rl_ERB3 -> RlP_ERB3P",1,"1/s"]
["R528","RlP_ERB3P -> EGF + RP_ERB3P",0.1,"1/s"]
["R529","EGF + RP_ERB3P -> RlP_ERB3P",0.01,"1/(nM*s)"]
["R530","RP_ERB3P -> RP + ERB3P",0.1,"1/s"]
["R531","RP + ERB3P -> RP_ERB3P",0.01,"1/(nM*s)"]
["R532","Rl + ERB3 -> Rl_ERB3",0.001,"1/(nM*s)"]
["R533","Rl_ERB3 -> Rl + ERB3",0.1,"1/s"]
["R534","ERB3P + R -> R_ERB3P",0.001,"1/(nM*s)"]
["R535","R_ERB3P -> ERB3P + R",0.1,"1/s"]
["R536","RlP_ERB3P -> RlP + ERB3P",0.1,"1/s"]
["R537","RlP + ERB3P -> RlP_ERB3P",0.01,"1/(nM*s)"]
["R538","RP + ERB3 -> RP_ERB3",0.001,"1/(nM*s)"]
["R539","RP_ERB3 -> RP + ERB3",0.1,"1/s"]
["R540","RP_ERB3 -> RP_ERB3P",1,"1/s"]
["R541","ERB3 + ERB3 -> ERB3_ERB3",0.0001,"1/(nM*s)"]
["R542","ERB3_ERB3 -> ERB3 + ERB3",0.1,"1/s"]
["R543","ERB3P + ERB -> ERB3P_ERB",0.01,"1/(nM*s)"]
["R544","ERB3P_ERB -> ERB3P + ERB",0.1,"1/s"]
["R545","ERB3P_ERB3P -> ERB3P + ERB3P",0.1,"1/s"]
["R546","ERB3P + ERB3P -> ERB3P_ERB3P",0.01,"1/(nM*s)"]
["R547","ERB3 + ERB -> ERB3_ERB",0.001,"1/(nM*s)"]
["R548","ERB3_ERB -> ERB3 + ERB",0.1,"1/s"]
["R549","EGF + ERB3_ERB -> EGF_ERB3_ERB",0.0001,"1/(nM*s)"]
["R550","EGF_ERB3_ERB -> EGF + ERB3_ERB",0.1,"1/s"]
["R551","ERB3 + ERBP -> ERB3_ERBP",0.001,"1/(nM*s)"]
["R552","ERB3_ERBP -> ERB3 + ERBP",0.1,"1/s"]
["R553","ERB3_ERBP -> ERB3P_ERBP",1,"1/s"]
["R554","ERB3P_ERBP -> ERB3P + ERBP",0.1,"1/s"]
["R555","ERB3P + ERBP -> ERB3P_ERBP",0.001,"1/(nM*s)"]
["R556","EGF + ERB3 -> EGF_ERB3",0.0001,"1/(nM*s)"]
["R557","EGF_ERB3 -> EGF + ERB3",0.1,"1/s"]
["R558","EGF_ERB3 + R -> EGF_ERB3_R",0.0001,"1/(nM*s)"]
["R559","EGF_ERB3_R -> EGF_ERB3 + R",0.1,"1/s"]
["R560","EGF_ERB3 + RP -> EGF_ERB3_RP",0.0001,"1/(nM*s)"]
["R561","EGF_ERB3_RP -> EGF_ERB3 + RP",0.1,"1/s"]
["R562","EGF_ERB3_RP -> EGF_ERB3P_RP",1,"1/s"]
["R563","EGF_ERB3P_RP -> EGF + RP_ERB3P",0.1,"1/s"]
["R564","EGF + RP_ERB3P -> EGF_ERB3P_RP",0.0001,"1/(nM*s)"]
["R565","EGF_ERB3P_RP -> EGF_ERB3P + RP",0.1,"1/s"]
["R566","EGF_ERB3P + RP -> EGF_ERB3P_RP",0.0001,"1/(nM*s)"]
["R567","EGF_ERB3 + ERBP -> EGF_ERB3_ERBP",0.0001,"1/(nM*s)"]
["R568","EGF_ERB3_ERBP -> EGF_ERB3 + ERBP",0.1,"1/s"]
["R569","EGF_ERB3_ERBP -> EGF_ERB3P_ERBP",1,"1/s"]
["R570","EGF_ERB3P_ERBP -> EGF + ERB3P_ERBP",0.1,"1/s"]
["R571","EGF + ERB3P_ERBP -> EGF_ERB3P_ERBP",0.0001,"1/(nM*s)"]
["R572","EGF_ERB3 + ERB -> EGF_ERB3_ERB",0.0001,"1/(nM*s)"]
["R573","EGF_ERB3_ERB -> EGF_ERB3 + ERB",0.1,"1/s"]
["R574","EGF_ERB3P_ERBP -> EGF_ERB3P + ERBP",0.1,"1/s"]
["R575","EGF_ERB3P + ERBP -> EGF_ERB3P_ERBP",0.0001,"1/(nM*s)"]
["R576","EGF_ERB3 + ERB3 -> EGF_ERB3_ERB3",0.0001,"1/(nM*s)"]
["R577","EGF_ERB3_ERB3 -> EGF_ERB3 + ERB3",0.1,"1/s"]
["R578","EGF + ERB3_ERB3 -> EGF_ERB3_ERB3",0.0001,"1/(nM*s)"]
["R579","EGF_ERB3_ERB3 -> EGF + ERB3_ERB3",0.1,"1/s"]
["R580","CDC25CP + ERB3P -> CDC25CP_ERB3P",0.01,"1/(nM*s)"]
["R581","CDC25CP_ERB3P -> CDC25CP + ERB3P",0.1,"1/s"]
["R582","CDC25CP_ERB3P -> CDC25CP + ERB3",0.5,"1/s"]
["R583","CDC25CP + ERB3P_ERB3P -> CDC25CP_ERB3P_ERB3P",0.01,"1/(nM*s)"]
["R584","CDC25CP_ERB3P_ERB3P -> CDC25CP + ERB3P_ERB3P",0.1,"1/s"]
["R585","CDC25CP_ERB3P_ERB3P -> CDC25CP + ERB3_ERB3",0.5,"1/s"]
["R586","ERB3P + ERB3 -> ERB3P_ERB3",0.001,"1/(nM*s)"]
["R587","ERB3P_ERB3 -> ERB3P + ERB3",0.1,"1/s"]
["R588","R_ERB3P + EGF -> Rl_ERB3P",0.01,"1/(nM*s)"]
["R589","Rl_ERB3P -> R_ERB3P + EGF",0.1,"1/s"]
["R590","Rl_ERB3P -> RlP_ERB3P",1,"1/s"]
["R591","RP_ERB3P -> ERB3P + RP",0.1,"1/s"]
["R592","ERB3P + RP -> RP_ERB3P",0.01,"1/(nM*s)"]
["R593","ERBP_PKP + PhoB -> ERBP_PKP_PhoB",0.001,"1/(nM*s)"]
["R594","ERBP_PKP_PhoB -> ERBP_PKP + PhoB",0.038,"1/s"]
["R595","ERBP_PKP_PhoB -> ERBP_PK + PhoB",0.595,"1/s"]
["R596","ERB3P_PKP + PhoB -> ERB3P_PKP_PhoB",0.001,"1/(nM*s)"]
["R597","ERB3P_PKP_PhoB -> ERB3P_PKP + PhoB",0.038,"1/s"]
["R598","ERB3P_PKP_PhoB -> ERB3P_PK + PhoB",0.595,"1/s"]
["R599","RP_PKP + PhoB -> RP_PKP_PhoB",0.001,"1/(nM*s)"]
["R600","RP_PKP_PhoB -> RP_PKP + PhoB",0.038,"1/s"]
["R601","RP_PKP_PhoB -> RP_PK + PhoB",0.595,"1/s"]
["R602","ERB_ERB -> ERBP_ERBP",1,"1/s"]
["R603","BetaCatenin + Cadh -> BetaCatenin_Cadh",0.01,"1/(nM*s)"]
["R604","BetaCatenin_Cadh -> BetaCatenin + Cadh",0.01,"1/s"]
["R605","BetaCatenin_Cadh + PTP -> BetaCatenin_Cadh_PTP",0.01,"1/(nM*s)"]
["R606","BetaCatenin_Cadh_PTP -> BetaCatenin_Cadh + PTP",1,"1/s"]
["R607","Cadh + PTP -> Cadh_PTP",0.01,"1/(nM*s)"]
["R608","Cadh_PTP -> Cadh + PTP",1,"1/s"]
["R609","BetaCatenin_Cadh + RP -> BetaCatenin_Cadh_RP",2.5,"1/(nM*s)"]
["R610","BetaCatenin_Cadh_RP -> BetaCatenin_Cadh + RP",1,"1/s"]
["R611","BetaCatenin_Cadh_RP -> BetaCateninY654 + Cadh + RP",1,"1/s"]
["R612","Cadh_PTP + BetaCateninY654 -> BetaCateninY654_Cadh_PTP",0.01,"1/(nM*s)"]
["R613","BetaCateninY654_Cadh_PTP -> Cadh_PTP + BetaCateninY654",0.1,"1/s"]
["R614","BetaCateninY654_Cadh_PTP -> BetaCatenin + Cadh_PTP",1,"1/s"]
["R615","BetaCatenin_Cadh_PTP -> BetaCatenin + Cadh_PTP",0.1,"1/s"]
["R616","BetaCatenin + Cadh_PTP -> BetaCatenin_Cadh_PTP",0.01,"1/(nM*s)"]
["R617","BetaCatenin_Cadh + ERBP -> BetaCatenin_Cadh_ERBP",2.5,"1/(nM*s)"]
["R618","BetaCatenin_Cadh_ERBP -> BetaCatenin_Cadh + ERBP",1,"1/s"]
["R619","BetaCatenin_Cadh_ERBP -> BetaCateninY654 + Cadh + ERBP",1,"1/s"]
["R620","TGF + TGF -> DIMTGF",0.01,"1/(nM*s)"]
["R621","DIMTGF -> TGF + TGF",0.01,"1/s"]
["R622","DIMTGF + DIMTBRII -> DIMTGF_DIMTBRII",0.01,"1/(nM*s)"]
["R623","DIMTGF_DIMTBRII -> DIMTGF + DIMTBRII",0.03,"1/s"]
["R624","DIMTGF_DIMTBRII + DIMTBRI -> DIMTGF_DIMTBRII_DIMTBRI",0.01,"1/(nM*s)"]
["R625","DIMTGF_DIMTBRII_DIMTBRI -> DIMTGF_DIMTBRII + DIMTBRI",0.01,"1/s"]
["R626","DIMTGF_DIMTBRII_DIMTBRI -> DIMTGF_DIMTBRII_DIMTBRIP",0.1,"1/s"]
["R627","DIMTGF_DIMTBRII_DIMTBRIP + SMADII -> DIMTGF_DIMTBRII_DIMTBRIP_SMADII",0.01,"1/(nM*s)"]
["R628","DIMTGF_DIMTBRII_DIMTBRIP_SMADII -> DIMTGF_DIMTBRII_DIMTBRIP + SMADII",10,"1/s"]
["R629","TBRI + TBRI -> DIMTBRI",0.01,"1/(nM*s)"]
["R630","DIMTBRI -> TBRI + TBRI",0.1,"1/s"]
["R631","TBRII + TBRII -> DIMTBRII",0.01,"1/(nM*s)"]
["R632","DIMTBRII -> TBRII + TBRII",0.1,"1/s"]
["R633","DIMTGF_DIMTBRII_DIMTBRIP_SMADII -> DIMTGF_DIMTBRII_DIMTBRIP + SMADIIP",1,"1/s"]
["R634","DIMTGF_DIMTBRII_DIMTBRIP + SMADIII -> DIMTGF_DIMTBRII_DIMTBRIP_SMADIII",0.01,"1/(nM*s)"]
["R635","DIMTGF_DIMTBRII_DIMTBRIP_SMADIII -> DIMTGF_DIMTBRII_DIMTBRIP + SMADIII",10,"1/s"]
["R636","DIMTGF_DIMTBRII_DIMTBRIP_SMADIII -> DIMTGF_DIMTBRII_DIMTBRIP + SMADIIIP",1,"1/s"]
["R637","DIMTGF_DIMTBRII_DIMTBRIP + TAK -> DIMTGF_DIMTBRII_DIMTBRIP_TAK",0.01,"1/(nM*s)"]
["R638","DIMTGF_DIMTBRII_DIMTBRIP_TAK -> DIMTGF_DIMTBRII_DIMTBRIP + TAK",0.01,"1/s"]
["R639","DIMTGF_DIMTBRII_DIMTBRIP_TAK -> DIMTGF_DIMTBRII_DIMTBRIP + TAKP",10,"1/s"]
["R640","NLKP + TCFLEF -> NLKP_TCFLEF",0.01,"1/(nM*s)"]
["R641","NLKP_TCFLEF -> NLKP + TCFLEF",1,"1/s"]
["R642","NLKP_TCFLEF -> NLKP + TCFLEFP",1,"1/s"]
["R643","TCFLEFP + Pase8 -> TCFLEFP_Pase8",0.01,"1/(nM*s)"]
["R644","TCFLEFP_Pase8 -> TCFLEFP + Pase8",1,"1/s"]
["R645","TCFLEFP_Pase8 -> TCFLEF + Pase8",0.1,"1/s"]
["R646","TAKP + Pase9 -> TAKP_Pase9",0.01,"1/(nM*s)"]
["R647","TAKP_Pase9 -> TAKP + Pase9",1,"1/s"]
["R648","TAKP_Pase9 -> TAK + Pase9",0.1,"1/s"]
["R649","NLKP + Pase10 -> NLKP_Pase10",0.01,"1/(nM*s)"]
["R650","NLKP_Pase10 -> NLKP + Pase10",1,"1/s"]
["R651","NLKP_Pase10 -> NLK + Pase10",0.1,"1/s"]
["R652","SMADIIP + SMAD4 -> SMADIIP_SMAD4",0.01,"1/(nM*s)"]
["R653","SMADIIP_SMAD4 -> SMADIIP + SMAD4",0.01,"1/s"]
["R654","SMADIIIP + SMAD4 -> SMADIIIP_SMAD4",0.01,"1/(nM*s)"]
["R655","SMADIIIP_SMAD4 -> SMADIIIP + SMAD4",0.01,"1/s"]
["R656","TCFLEF + BetaCatenin -> TCFLEF_BetaCatenin",0.01,"1/(nM*s)"]
["R657","TCFLEF_BetaCatenin -> TCFLEF + BetaCatenin",10,"1/s"]
["R658","SMADIIIP + PP1A -> SMADIIIP_PP1A",0.01,"1/(nM*s)"]
["R659","SMADIIIP_PP1A -> SMADIIIP + PP1A",10,"1/s"]
["R660","SMADIIIP_PP1A -> SMADIII + PP1A",0.1,"1/s"]
["R661","SMADIIP + PP1A -> SMADIIP_PP1A",0.01,"1/(nM*s)"]
["R662","SMADIIP_PP1A -> SMADIIP + PP1A",10,"1/s"]
["R663","SMADIIP_PP1A -> SMADII + PP1A",0.1,"1/s"]
["R664","TCFLEF + BetaCateninY654 -> TCFLEF_BetaCateninY654",0.01,"1/(nM*s)"]
["R665","TCFLEF_BetaCateninY654 -> TCFLEF + BetaCateninY654",10,"1/s"]
["R666","TCFLEF_BetaCateninY654 + TFBS -> TCFLEF_BetaCateninY654_TFBS",0.01,"1/(nM*s)"]
["R667","TCFLEF_BetaCateninY654_TFBS -> TCFLEF_BetaCateninY654 + TFBS",0.01,"1/s"]
["R668","TCFLEF_BetaCatenin + TFBS -> TCFLEF_BetaCatenin_TFBS",0.01,"1/(nM*s)"]
["R669","TCFLEF_BetaCatenin_TFBS -> TCFLEF_BetaCatenin + TFBS",0.02,"1/s"]
["R670","DIMTGF_DIMTBRII + DIMTBRIP -> DIMTGF_DIMTBRII_DIMTBRIP",0.01,"1/(nM*s)"]
["R671","DIMTGF_DIMTBRII_DIMTBRIP -> DIMTGF_DIMTBRII + DIMTBRIP",0.1,"1/s"]
["R672","DIMTBRIP + PP1C -> DIMTBRIP_PP1C",0.01,"1/(nM*s)"]
["R673","DIMTBRIP_PP1C -> DIMTBRIP + PP1C",1,"1/s"]
["R674","DIMTBRIP_PP1C -> DIMTBRI + PP1C",0.5,"1/s"]
["R675","SMADIIP_SMAD4 + TFBSI -> SMADIIP_SMAD4_TFBSI",0.01,"1/(nM*s)"]
["R676","SMADIIP_SMAD4_TFBSI -> SMADIIP_SMAD4 + TFBSI",0.1,"1/s"]
["R677","SMADIIIP_SMAD4 + TFBSI -> SMADIIIP_SMAD4_TFBSI",0.01,"1/(nM*s)"]
["R678","SMADIIIP_SMAD4_TFBSI -> SMADIIIP_SMAD4 + TFBSI",0.1,"1/s"]
["R679","Ras_GTP + PI3K -> Ras_GTP_PK",0.001,"1/(nM*s)"]
["R680","Ras_GTP_PK -> Ras_GTP + PI3K",15,"1/s"]
["R681","Ras_GTP_PK -> Ras_GTP_PKP",0.1,"1/s"]
["R682","Ras_GTP_PKP -> Ras_GTP + PKP",15,"1/s"]
["R683","Ras_GTP + PKP -> Ras_GTP_PKP",0.001,"1/(nM*s)"]
["R684","Ras_GTP_PKP + PIP2 -> Ras_GTP_PKP_PIP2",0.625,"1/(nM*s)"]
["R685","Ras_GTP_PKP_PIP2 -> Ras_GTP_PKP + PIP2",10,"1/s"]
["R686","Ras_GTP_PKP + PhoB -> Ras_GTP_PKP_PhoB",0.01,"1/(nM*s)"]
["R687","Ras_GTP_PKP_PhoB -> Ras_GTP_PKP + PhoB",1,"1/s"]
["R688","Ras_GTP_PKP_PhoB -> Ras_GTP + PI3K + PhoB",0.5,"1/s"]
["R689","Ras_GTP_PKP_PIP2 -> Ras_GTP_PKP + PIP3",2.5,"1/s"]
["R690","ERKPP + AP1 -> ERKPP_AP1",0.01,"1/(nM*s)"]
["R691","ERKPP_AP1 -> ERKPP + AP1",10,"1/s"]
["R692","ERKPP_AP1 -> ERKPP + AP1P",1,"1/s"]
["R693","AP1P + Pase12 -> AP1P_Pase12",0.01,"1/(nM*s)"]
["R694","AP1P_Pase12 -> AP1P + Pase12",0.1,"1/s"]
["R695","AP1P_Pase12 -> AP1 + Pase12",1,"1/s"]
["R696","AP1 + TFBSII -> AP1_TFBSII",0.01,"1/(nM*s)"]
["R697","AP1_TFBSII -> AP1 + TFBSII",7,"1/s"]
["R698","AP1P + TFBSII -> AP1P_TFBSII",0.01,"1/(nM*s)"]
["R699","AP1P_TFBSII -> AP1P + TFBSII",0.35,"1/s"]
["R700","WNT + FRZ -> WNT_FRZ",0.01,"1/(nM*s)"]
["R701","WNT_FRZ -> WNT + FRZ",0.04,"1/s"]
["R702","WNT_FRZ + LRP6 -> WNT_FRZ_LRP6",0.01,"1/(nM*s)"]
["R703","WNT_FRZ_LRP6 -> WNT_FRZ + LRP6",0.04,"1/s"]
["R704","WNT_FRZ_LRP6 + DVL -> WNT_FRZ_LRP6_DVL",0.01,"1/(nM*s)"]
["R705","WNT_FRZ_LRP6_DVL -> WNT_FRZ_LRP6 + DVL",0.04,"1/s"]
["R706","AXN + GSK -> AXN_GSK",0.01,"1/(nM*s)"]
["R707","AXN_GSK -> AXN + GSK",0.1,"1/s"]
["R708","AXN_GSK -> AXNP_GSK",1,"1/s"]
["R709","AXNP_GSK + APC -> AXNP_GSK_APC",0.01,"1/(nM*s)"]
["R710","AXNP_GSK_APC -> AXNP_GSK + APC",0.1,"1/s"]
["R711","AXNP_GSK_APC -> AXNP_GSK_APCP",1,"1/s"]
["R712","WNT_FRZ_LRP6_DVL + GSK -> WNT_FRZ_LRP6_DVL_GSK",0.01,"1/(nM*s)"]
["R713","WNT_FRZ_LRP6_DVL_GSK -> WNT_FRZ_LRP6_DVL + GSK",0.04,"1/s"]
["R714","WNT_FRZ_LRP6_DVL_GSK -> WNT_FRZ_LRP6P_DVL_GSK",1,"1/s"]
["R715","WNT_FRZ_LRP6P_DVL_GSK + AXN -> WNT_FRZ_LRP6P_DVL_GSK_AXN",0.01,"1/(nM*s)"]
["R716","WNT_FRZ_LRP6P_DVL_GSK_AXN -> WNT_FRZ_LRP6P_DVL_GSK + AXN",0.04,"1/s"]
["R717","AXNP_GSK_APCP + BetaCatenin -> AXNP_GSK_APCP_BetaCatenin",0.01,"1/(nM*s)"]
["R718","AXNP_GSK_APCP_BetaCatenin -> AXNP_GSK_APCP + BetaCatenin",0.1,"1/s"]
["R719","AXNP_GSK_APCP_BetaCatenin -> AXNP_GSK_APCP + BetaCateninP",1,"1/s"]
["R720","BetaCateninP -> null",1,"1/s"]
["R721","BetaCatenin_generator -> BetaCatenin",0.05,"1/s"]
["R722","WNT_FRZ_LRP6P_DVL_GSK + PhoE -> WNT_FRZ_LRP6P_DVL_GSK_PhoE",0.01,"1/(nM*s)"]
["R723","WNT_FRZ_LRP6P_DVL_GSK_PhoE -> WNT_FRZ_LRP6P_DVL_GSK + PhoE",0.1,"1/s"]
["R724","WNT_FRZ_LRP6P_DVL_GSK_PhoE -> WNT_FRZ_LRP6_DVL + GSK + PhoE",0.5,"1/s"]
["R725","AXNP_GSK + PhoE -> AXNP_GSK_PhoE",0.01,"1/(nM*s)"]
["R726","AXNP_GSK_PhoE -> AXNP_GSK + PhoE",0.1,"1/s"]
["R727","AXNP_GSK_PhoE -> AXN + GSK + PhoE",0.5,"1/s"]
["R728","BetaCateninP + PhoE -> BetaCateninP_PhoE",0.01,"1/(nM*s)"]
["R729","BetaCateninP_PhoE -> BetaCateninP + PhoE",0.1,"1/s"]
["R730","BetaCateninP_PhoE -> BetaCatenin + PhoE",1,"1/s"]
["R731","AXNP_GSK -> AXNP + GSK",0.1,"1/s"]
["R732","AXNP + GSK -> AXNP_GSK",0.01,"1/(nM*s)"]
["R733","AXNP + PhoE -> AXNP_PhoE",0.01,"1/(nM*s)"]
["R734","AXNP_PhoE -> AXNP + PhoE",0.1,"1/s"]
["R735","AXNP_PhoE -> AXN + PhoE",1,"1/s"]
["R736","AXNP_GSK_APCP -> AXNP_GSK + APCP",0.1,"1/s"]
["R737","AXNP_GSK + APCP -> AXNP_GSK_APCP",0.01,"1/(nM*s)"]
["R738","APCP + PhoE -> APCP_PhoE",0.01,"1/(nM*s)"]
["R739","APCP_PhoE -> APCP + PhoE",0.1,"1/s"]
["R740","APCP_PhoE -> APC + PhoE",1,"1/s"]
["R741","PIP2_generator -> PIP2",10,"1/s"]
["R742","PIP2 + PLCyP -> PIP2_PLCyP",0.01,"1/(nM*s)"]
["R743","PIP2_PLCyP -> PIP2 + PLCyP",10,"1/s"]
["R744","PIP2_PLCyP -> IP3 + DAG + PLCyP",0.001,"1/s"]
["R745","DAG + PKC -> DAG_PKC",0.01,"1/(nM*s)"]
["R746","DAG_PKC -> DAG + PKC",0.1,"1/s"]
["R747","IP3 -> null",1e-05,"1/s"]
["R748","DAG -> null",1e-05,"1/s"]
["R749","DAG_PKC + Raf -> DAG_PKC_Raf",0.01,"1/(nM*s)"]
["R750","DAG_PKC_Raf -> DAG_PKC + Raf",0.1,"1/s"]
["R751","DAG_PKC_Raf -> DAG + PKC + [Raf*]",10,"1/s"]
["R752","WNT_FRZ_LRP6 + TAK -> WNT_FRZ_LRP6_TAK",0.01,"1/(nM*s)"]
["R753","WNT_FRZ_LRP6_TAK -> WNT_FRZ_LRP6 + TAK",10,"1/s"]
["R754","WNT_FRZ_LRP6_TAK -> WNT_FRZ_LRP6 + TAKP",0.1,"1/s"]
["R755","TAKP + TAB -> TAKP_TAB",0.01,"1/(nM*s)"]
["R756","TAKP_TAB -> TAKP + TAB",10,"1/s"]
["R757","TAKP_TAB + NLK -> TAKP_TAB_NLK",0.01,"1/(nM*s)"]
["R758","TAKP_TAB_NLK -> TAKP_TAB + NLK",10,"1/s"]
["R759","TAKP_TAB_NLK -> TAKP_TAB + NLKP",1,"1/s"]
["R760","GROUCHO + TCFLEF -> GROUCHO_TCFLEF",0.01,"1/(nM*s)"]
["R761","GROUCHO_TCFLEF -> GROUCHO + TCFLEF",10,"1/s"]
["R762","GROUCHO_TCFLEF + TFBS -> GROUCHO_TCFLEF_TFBS",0.01,"1/(nM*s)"]
["R763","GROUCHO_TCFLEF_TFBS -> GROUCHO_TCFLEF + TFBS",1,"1/s"]
["R764","APC + BetaCatenin -> APC_BetaCatenin",0.01,"1/(nM*s)"]
["R765","APC_BetaCatenin -> APC + BetaCatenin",12,"1/s"]
["R766","SMAD4 + TCFLEF -> SMAD4_TCFLEF",0.01,"1/(nM*s)"]
["R767","SMAD4_TCFLEF -> SMAD4 + TCFLEF",1,"1/s"]
["R768","SMAD4_TCFLEF + TFBS -> SMAD4_TCFLEF_TFBS",0.01,"1/(nM*s)"]
["R769","SMAD4_TCFLEF_TFBS -> SMAD4_TCFLEF + TFBS",1,"1/s"]
["R770","PIP2 -> null",0.0004,"1/s"]
["R771","BetaCatenin -> null",1e-07,"1/s"]
["R772","PIP3 -> null",0.0001,"1/s"]
["R773","AXNP_GSK + BetaCatenin -> AXNP_GSK_BetaCatenin",0.01,"1/(nM*s)"]
["R774","AXNP_GSK_BetaCatenin -> AXNP_GSK + BetaCatenin",10000,"1/s"]
["R775","AXNP_GSK_BetaCatenin -> AXNP_GSK + BetaCateninP",1,"1/s"]
["R776","G_S + ERKPP -> G_S_ERKPP",0.01,"1/(nM*s)"]
["R777","G_S_ERKPP -> G_S + ERKPP",0.033,"1/s"]
["R778","G_S_ERKPP -> Grb + SOSP + ERKPP",1,"1/s"]
["R779","AKTP + MDM2 -> AKTP_MDM2",0.01,"1/(nM*s)"]
["R780","AKTP_MDM2 -> AKTP + MDM2",0.1,"1/s"]
["R781","AKTP_MDM2 -> AKTP + MDM2P",0.1,"1/s"]
["R782","MDM2P + TP53 -> MDM2P_TP53",0.01,"1/(nM*s)"]
["R783","MDM2P_TP53 -> MDM2P + TP53",0.1,"1/s"]
["R784","MDM2P_TP53 -> MDM2P + TP53U",1,"1/s"]
["R785","TP53U -> null",1,"1/s"]
["R786","TP53_generator -> TP53",0.05,"1/s"]
["R787","MDM2P + Pho13 -> MDM2P_Pho13",0.01,"1/(nM*s)"]
["R788","MDM2P_Pho13 -> MDM2P + Pho13",0.1,"1/s"]
["R789","MDM2P_Pho13 -> MDM2 + Pho13",1,"1/s"]
["R790","TP53 + TFBSIV -> TP53_TFBSIV",0.01,"1/(nM*s)"]
["R791","TP53_TFBSIV -> TP53 + TFBSIV",0.1,"1/s"]
["R792","RP_ShP_G_GABP + ERKPP -> RP_ShP_G_GABP_ERKPP",0.01,"1/(nM*s)"]
["R793","RP_ShP_G_GABP_ERKPP -> RP_ShP_G_GABP + ERKPP",0.1,"1/s"]
["R794","RP_ShP_G_GABP_ERKPP -> RP_ShP_G + GABPP + ERKPP",1,"1/s"]
["R795","RP_G_GABP + ERKPP -> RP_G_GABP_ERKPP",0.01,"1/(nM*s)"]
["R796","RP_G_GABP_ERKPP -> RP_G_GABP + ERKPP",0.1,"1/s"]
["R797","RP_G_GABP_ERKPP -> RP_G + GABPP + ERKPP",1,"1/s"]
["R798","ERBP_ShP_G_GABP + ERKPP -> ERBP_ShP_G_GABP_ERKPP",0.01,"1/(nM*s)"]
["R799","ERBP_ShP_G_GABP_ERKPP -> ERBP_ShP_G_GABP + ERKPP",0.1,"1/s"]
["R800","ERBP_ShP_G_GABP_ERKPP -> ERBP_ShP_G + GABPP + ERKPP",1,"1/s"]
["R801","ERBP_G_GABP + ERKPP -> ERBP_G_GABP_ERKPP",0.01,"1/(nM*s)"]
["R802","ERBP_G_GABP_ERKPP -> ERBP_G_GABP + ERKPP",0.1,"1/s"]
["R803","ERBP_G_GABP_ERKPP -> ERBP_G + GABPP + ERKPP",1,"1/s"]
["R804","ERB3P_G_GABP + ERKPP -> ERB3P_G_GABP_ERKPP",0.01,"1/(nM*s)"]
["R805","ERB3P_G_GABP_ERKPP -> ERB3P_G_GABP + ERKPP",0.1,"1/s"]
["R806","ERB3P_G_GABP_ERKPP -> ERB3P_G + GABPP + ERKPP",1,"1/s"]
["R807","ERB3P_ShP_G_GABP + ERKPP -> ERB3P_ShP_G_GABP_ERKPP",0.01,"1/(nM*s)"]
["R808","ERB3P_ShP_G_GABP_ERKPP -> ERB3P_ShP_G_GABP + ERKPP",0.1,"1/s"]
["R809","ERB3P_ShP_G_GABP_ERKPP -> ERB3P_ShP_G + GABPP + ERKPP",1,"1/s"]
["R810","GABP + ERKPP -> GABP_ERKPP",0.01,"1/(nM*s)"]
["R811","GABP_ERKPP -> GABP + ERKPP",0.1,"1/s"]
["R812","GABPP + PhoA -> GABPP_PhoA",0.01,"1/(nM*s)"]
["R813","GABPP_PhoA -> GABPP + PhoA",0.1,"1/s"]
["R814","GABPP_PhoA -> GABP + PhoA",1,"1/s"]
["R815","GABP_ERKPP -> GABPP + ERKPP",1,"1/s"]
["R816","ARF + MDM2 -> ARF_MDM2",0.01,"1/(nM*s)"]
["R817","ARF_MDM2 -> ARF + MDM2",0.001,"1/s"]
["R818","CYCLIND1 + CDK4 -> CYCLIND1_CDK4",0.01,"1/(nM*s)"]
["R819","CYCLIND1_CDK4 -> CYCLIND1 + CDK4",0.1,"1/s"]
["R820","CYCLINE + CDK2 -> CYCLINE_CDK2",0.01,"1/(nM*s)"]
["R821","CYCLINE_CDK2 -> CYCLINE + CDK2",0.1,"1/s"]
["R822","E2F + DP1 -> E2F_DP1",0.01,"1/(nM*s)"]
["R823","E2F_DP1 -> E2F + DP1",0.1,"1/s"]
["R824","E2F_DP1 + RB -> E2F_DP1_RB",0.01,"1/(nM*s)"]
["R825","E2F_DP1_RB -> E2F_DP1 + RB",0.1,"1/s"]
["R826","CYCLIND1_CDK4 + RB -> CYCLIND1_CDK4_RB",0.01,"1/(nM*s)"]
["R827","CYCLIND1_CDK4_RB -> CYCLIND1_CDK4 + RB",0.1,"1/s"]
["R828","CYCLIND1_CDK4_RB -> CYCLIND1_CDK4 + RBP",1,"1/s"]
["R829","CYCLINE_CDK2 + RBP -> CYCLINE_CDK2_RBP",0.01,"1/(nM*s)"]
["R830","CYCLINE_CDK2_RBP -> CYCLINE_CDK2 + RBP",0.1,"1/s"]
["R831","CYCLINE_CDK2_RBP -> CYCLINE_CDK2 + RBPP",1,"1/s"]
["R832","RBPP + Pho14 -> RBPP_Pho14",0.01,"1/(nM*s)"]
["R833","RBPP_Pho14 -> RBPP + Pho14",0.1,"1/s"]
["R834","RBPP_Pho14 -> RBP + Pho14",1,"1/s"]
["R835","RBP + Pho14 -> RBP_Pho14",0.01,"1/(nM*s)"]
["R836","RBP_Pho14 -> RBP + Pho14",0.1,"1/s"]
["R837","RBP_Pho14 -> RB + Pho14",1,"1/s"]
["R838","E2F_DP1_RB + TFBSV -> E2F_DP1_RB_TFBSV",0.01,"1/(nM*s)"]
["R839","E2F_DP1_RB_TFBSV -> E2F_DP1_RB + TFBSV",0.1,"1/s"]
["R840","E2F_DP1 + TFBSV -> E2F_DP1_TFBSV",0.01,"1/(nM*s)"]
["R841","E2F_DP1_TFBSV -> E2F_DP1 + TFBSV",0.1,"1/s"]
["R842","CYCLIND1_CDK4 + P16 -> CYCLIND1_CDK4_P16",0.01,"1/(nM*s)"]
["R843","CYCLIND1_CDK4_P16 -> CYCLIND1_CDK4 + P16",0.1,"1/s"]
["R844","CDC25C + ERKPP -> CDC25C_ERKPP",0.01,"1/(nM*s)"]
["R845","CDC25C_ERKPP -> CDC25C + ERKPP",0.01,"1/s"]
["R846","CDC25C_ERKPP -> CDC25CP + ERKPP",10,"1/s"]
["R847","CDC25CP + Pho16 -> CDC25CP_Pho16",0.01,"1/(nM*s)"]
["R848","CDC25CP_Pho16 -> CDC25CP + Pho16",10,"1/s"]
["R849","CDC25CP_Pho16 -> CDC25C + Pho16",0.1,"1/s"]
["R850","BetaCateninY654 -> null",5.79e-06,"1/s"]

{"sheet":"Sheet2","index":1,"n_rows":0,"n_cols":0,"rows_kept":0}

{"sheet":"Sheet3","index":2,"n_rows":0,"n_cols":0,"rows_kept":0}