{"text_format":"3","workbook":"xlsx","n_sheets":3,"sheets":["Sheet1","Sheet2","Sheet3"],"read":"whole","date_system":"1900"}

{"sheet":"Sheet1","index":0,"n_rows":324,"n_cols":11,"rows_kept":324}
["GoF KRAS",null,null,"LoF APC",null,null,"LoF SMAD4",null,null,"LoF TP53"]
["Protein","δi",null,"Protein","δi",null,"Protein","δi",null,"Protein","δi"]
["RP_GAP_Ras_GTP",-1,null,"BetaCateninP",-1,null,"DIMTGF_DIMTBRII_DIMTBRIP_SMADII",0.09,null,"TP53",-1]
["RP_G_GABP_GAP_Ras_GTP",-1,null,"BetaCateninP_PhoE",-1,null,"DIMTGF_DIMTBRII_DIMTBRIP_SMADIII",0.09,null,"MDM2P_TP53",-1]
["RP_ShP_G_GABP_GAP_Ras_GTP",-1,null,"Cadh",-0.99,null,"SMADIIP_PP1A",0.09,null,"TP53U",-1]
["ERBP_GAP_Ras_GTP",-1,null,"Cadh_PTP",-0.97,null,"SMADIIIP_PP1A",0.09,null,"TP53_generator",-1]
["ERBP_G_GABP_GAP_Ras_GTP",-1,null,"GROUCHO_TCFLEF_TFBS",-0.88,null,"SMADII",0.09,null,"TP53_TFBSIV",-1]
["ERBP_ShP_G_GABP_GAP_Ras_GTP",-1,null,"SMAD4_TCFLEF_TFBS",-0.87,null,"SMADIII",0.09,null,"TFBSIV",0.66]
["ERB3P_GAP_Ras_GTP",-1,null,"TFBS",-0.76,null,"SMADIIP",0.09]
["ERB3P_G_GABP_GAP_Ras_GTP",-1,null,"TCFLEFP",-0.51,null,"SMADIIIP",0.09]
["ERB3P_ShP_G_GABP_GAP_Ras_GTP",-1,null,"NLKP_TCFLEF",-0.51,null,"GROUCHO_TCFLEF",0.18]
["CDC25C",-1,null,"TCFLEFP_Pase8",-0.51,null,"NLKP_TCFLEF",0.18]
["RP_ShP_G_S_Ras_GDP",-0.99,null,"TCFLEF",-0.51,null,"TCFLEFP_Pase8",0.18]
["RP_ShP_G_S_Ras",-0.98,null,"GROUCHO_TCFLEF",-0.5,null,"TCFLEF",0.18]
["G_S",-0.98,null,"SMAD4_TCFLEF",-0.48,null,"TCFLEF_BetaCatenin",0.18]
["ERB3P_Sh_G_S_Ras_GDP",-0.98,null,"SMADIIIP_SMAD4_TFBSI",0.04,null,"TCFLEF_BetaCateninY654",0.18]
["RP_ShP_G_S",-0.98,null,"SMADIIP_SMAD4_TFBSI",0.04,null,"TCFLEFP",0.19]
["Ras_GDP",-0.98,null,"SMADIIIP_SMAD4",0.05,null,"GROUCHO_TCFLEF_TFBS",0.19]
["ERB3P_ERB3P",-0.98,null,"SMADIIP_SMAD4",0.05,null,"TCFLEF_BetaCatenin_TFBS",0.19]
["ERB3P_Sh_G_S_Ras",-0.97,null,"SMAD4",0.05,null,"TCFLEF_BetaCateninY654_TFBS",0.19]
["ERB3P_ShP_G_S",-0.96,null,"BetaCateninY654_Cadh_PTP",0.32,null,"TFBSI",0.25]
["RP_ShP_G_GABP",-0.96,null,"BetaCatenin_Cadh_ERBP",0.33]
["RP_ShP_G_GABP_PhoA",-0.96,null,"BetaCatenin_Cadh",0.33]
["RP_ShP_G_GABP_GAP",-0.96,null,"BetaCatenin_Cadh_RP",0.33]
["RP_ShP_G_GABP_PK",-0.96,null,"AXNP_GSK",0.34]
["RP_ShP_G_GABP_PKP_PhoB",-0.96,null,"AXNP",0.34]
["RP_ShP_G_GABP_PKP",-0.96,null,"AXNP_GSK_PhoE",0.34]
["RP_G_GABP",-0.96,null,"WNT_FRZ_LRP6P_DVL_GSK_AXN",0.34]
["RP_G_GABP_PhoA",-0.96,null,"AXN_GSK",0.34]
["RP_G_GABP_GAP",-0.96,null,"AXNP_PhoE",0.34]
["RP_ShP_G_GABP_PKP_PIP2",-0.96,null,"AXN",0.35]
["RP_G_GABP_PK",-0.96,null,"BetaCatenin_Cadh_PTP",0.38]
["GABP_PIP3",-0.96,null,"TCFLEF_BetaCateninY654_TFBS",4.53]
["RP_G_GABP_PKP_PhoB",-0.96,null,"TCFLEF_BetaCatenin_TFBS",8.71]
["RP_G_GABP_PKP",-0.96,null,"TCFLEF_BetaCateninY654",21.89]
["RP_G_S_Ras_GDP",-0.96,null,"TCFLEF_BetaCatenin",39.16]
["RP_G_GABP_PKP_PIP2",-0.96,null,"BetaCateninY654",45.45]
["RP_G_GAB_PIP3",-0.95,null,"BetaCatenin",80.49]
["RP_G_S",-0.95,null,"AXNP_GSK_BetaCatenin",108.55]
["RP_ShP_G_GAB_PIP3",-0.94]
["ERB3P_ShP_G_GABP",-0.93]
["ERB3P_ShP_G_GABP_PhoA",-0.93]
["ERB3P_ShP_G_GABP_GAP",-0.93]
["ERB3P_ShP_G_GABP_PK",-0.93]
["ERB3P_ShP_G_GABP_PKP_PhoB",-0.93]
["ERB3P_ShP_G_GABP_PKP",-0.93]
["ERB3P_G_GABP",-0.93]
["ERB3P_G_GABP_PhoA",-0.93]
["ERB3P_G_GABP_GAP",-0.93]
["ERB3P_ShP_G_GABP_PKP_PIP2",-0.93]
["ERB3P_G_GABP_PK",-0.93]
["ERB3P_G_GABP_PKP_PhoB",-0.93]
["ERB3P_G_GABP_PKP",-0.93]
["ERBP_ShP_G_S_Ras_GDP",-0.93]
["ERB3P_G_S_Ras_GDP",-0.93]
["ERB3P_G_GABP_PKP_PIP2",-0.93]
["ERK",-0.93]
["ERB3P_G_GAB_PIP3",-0.92]
["CDC25CP_ERB3P_ERB3P",-0.92]
["ERBP_ShP_G_GABP_PKP_PIP3",-0.91]
["ERB3P_G_S",-0.91]
["ERBP_G_GABP_PKP_PIP3",-0.91]
["ShP_G",-0.9]
["ERB3P_ShP_G_GAB_PIP3",-0.89]
["ERBP_ShP_G_S_Ras",-0.88]
["BetaCatenin_Cadh_RP",-0.88]
["GABP",-0.88]
["GABP_PhoA",-0.88]
["RP",-0.87]
["RP_GAP",-0.87]
["RP_PK",-0.87]
["RP_PLP",-0.87]
["RP_PL",-0.87]
["RP_PKP_PhoB",-0.87]
["RP_PKP",-0.87]
["RP_PKP_PIP2",-0.87]
["RP_R",-0.86]
["RP_G_GAB",-0.86]
["RP_G",-0.86]
["ERBP_ShP_G_S",-0.86]
["RP_Sh",-0.86]
["RP_ERB3",-0.85]
["EGF_ERB3_RP",-0.85]
["RP_ShP",-0.85]
["RP_ShP_G",-0.84]
["BetaCateninY654",-0.82]
["TCFLEF_BetaCateninY654",-0.82]
["TCFLEF_BetaCateninY654_TFBS",-0.81]
["RP_ShP_G_GAB",-0.81]
["DAG_PKC_Raf",-0.81]
["BetaCateninY654_Cadh_PTP",-0.78]
["MEK",-0.77]
["PLCyP",-0.77]
["ERB3P",-0.77]
["ERB3P_GAP",-0.77]
["ShP",-0.77]
["PIP2_PLCyP",-0.77]
["IP3",-0.77]
["DAG",-0.77]
["PLCyP_PaseX",-0.77]
["ERB3P_PK",-0.76]
["ERB3P_PLP",-0.76]
["ERB3P_PL",-0.76]
["ERB3P_PKP_PhoB",-0.76]
["ERB3P_PKP",-0.76]
["ERB3P_PKP_PIP2",-0.76]
["R_ERB3P",-0.76]
["Rl_ERB3P",-0.76]
["Pase2",-0.76]
["ERB3P_G_GAB",-0.75]
["ERB3P_G",-0.75]
["PTP1E_ShP",-0.75]
["ERB3P_Sh",-0.75]
["ERBP_ShP_G_GABP",-0.74]
["ERBP_ShP_G_GABP_PhoA",-0.74]
["ERBP_ShP_G_GABP_GAP",-0.74]
["ShP_G_S",-0.74]
["ERBP_ShP_G_GABP_PK",-0.74]
["ERB3P_ERB3",-0.74]
["ERB3P_ShP",-0.74]
["ERBP_ShP_G_GABP_PKP_PhoB",-0.73]
["ERBP_ShP_G_GABP_PKP",-0.73]
["ERBP_G_GABP",-0.73]
["ERBP_G_GABP_PhoA",-0.73]
["ERBP_G_GABP_GAP",-0.73]
["ERBP_ShP_G_GABP_PKP_PIP2",-0.73]
["ERBP_G_GABP_PK",-0.73]
["ERBP_G_GABP_PKP_PhoB",-0.72]
["RP_ERB",-0.72]
["ERBP_G_GABP_PKP",-0.72]
["RP_RP",-0.71]
["ERBP_G_S_Ras_GDP",-0.71]
["ERBP_G_GABP_PKP_PIP2",-0.71]
["Pase3",-0.71]
["ERB3P_ShP_G",-0.71]
["ERBP_G_GAB_PIP3",-0.68]
["PIP3",-0.68]
["PIP3_PTEN",-0.67]
["ERBP_G_S",-0.66]
["ERB3P_ShP_G_GAB",-0.66]
["GAB_PIP3",-0.65]
["AKTP",-0.65]
["AKT_PIP3",-0.64]
["AKT_PIP3_PDK1",-0.63]
["AKTP_TAKT",-0.63]
["Raf",-0.62]
["MDM2P",-0.58]
["AKTP_MDM2",-0.58]
["MDM2P_Pho13",-0.58]
["ERBP_ShP_G_GAB_PIP3",-0.58]
["EGF_ERB3P_RP",-0.51]
["CDC25CP_RP",-0.5]
["ERB3P_ERB",-0.49]
["DAG_PKC",-0.49]
["AXN",-0.48]
["AP1_TFBSII",-0.43]
["AP1",-0.39]
["TFBSIV",-0.35]
["RP_G_S_Ras",-0.32]
["RP_ERB3P",-0.27]
["BetaCatenin",-0.25]
["APC_BetaCatenin",-0.25]
["TCFLEF_BetaCatenin",-0.24]
["GSKP",-0.23]
["AKTP_GSK",-0.22]
["GSKP_PhoC",-0.22]
["TCFLEF_BetaCatenin_TFBS",-0.22]
["Pase1",-0.19]
["BetaCatenin_Cadh_ERBP",-0.16]
["WNT_FRZ_LRP6_DVL",-0.14]
["ARF",-0.13]
["CDC25CP_ERB3P",-0.11]
["ERBP",-0.1]
["WNT_FRZ_LRP6",-0.1]
["WNT_FRZ_LRP6_TAK",-0.1]
["ERBP_GAP",-0.09]
["PhoE",-0.09]
["ERBP_PK",-0.08]
["ERBP_PLP",-0.08]
["ERBP_PL",-0.08]
["ERBP_PKP_PhoB",-0.08]
["ERBP_PKP",-0.08]
["TAKP",-0.08]
["TAKP_TAB",-0.08]
["NLKP",-0.08]
["TAKP_TAB_NLK",-0.08]
["NLKP_Pase10",-0.08]
["TAKP_Pase9",-0.08]
["BetaCateninP_PhoE",-0.08]
["TFBSII",-0.07]
["TCFLEFP",-0.07]
["TCFLEFP_Pase8",-0.07]
["NLKP_TCFLEF",-0.07]
["BetaCatenin_Cadh_PTP",-0.07]
["BetaCatenin_Cadh",-0.07]
["ERBP_PKP_PIP2",-0.06]
["R_ERBP",-0.06]
["DVL",-0.05]
["LRP6",-0.05]
["WNT_FRZ",-0.05]
["FRZ",-0.05]
["Pho16",-0.03]
["ERBP_G_GAB",-0.03]
["TFBS",0.03]
["TAKT",0.03]
["SMAD4_TCFLEF_TFBS",0.04]
["GROUCHO_TCFLEF_TFBS",0.04]
["RP_ERBP",0.04]
["Rl",0.04]
["R",0.05]
["PTP1E",0.08]
["GAB",0.09]
["WNT_FRZ_LRP6P_DVL_GSK_AXN",0.09]
["Rl2",0.09]
["Rl2P",0.09]
["PKC",0.09]
["Shc",0.09]
["RlP_RP",0.09]
["Rl_R",0.09]
["R_R",0.1]
["CDC25CP_RP_RP",0.1]
["AXNP_PhoE",0.1]
["ERB3",0.13]
["EGF_ERB3",0.13]
["AKT",0.13]
["ERBP_ShP_G",0.14]
["Grb",0.14]
["AXN_GSK",0.16]
["RlP_ERB3P",0.17]
["Rl_ERB3",0.17]
["MDM2",0.18]
["R_ERB3",0.18]
["EGF_ERB3_R",0.18]
["Cadh_PTP",0.19]
["AXNP",0.21]
["Cadh",0.21]
["AXNP_GSK_PhoE",0.22]
["ERB3P_G_S_Ras",0.23]
["ERB3_ERB3",0.27]
["EGF_ERB3_ERB3",0.27]
["ERBP_ShP_G_GAB",0.34]
["AXNP_GSK",0.34]
["APCP_PhoE",0.34]
["AXNP_GSK_APC",0.34]
["AXNP_GSK_APCP",0.34]
["APCP",0.48]
["TP53_TFBSIV",0.54]
["EGF_ERB3P_ERBP",0.56]
["Raf*_AKTP",0.6]
["Raf**_Pase1",0.6]
["RlP",0.61]
["RP_ShP_G_S_Ras_GTP",0.7]
["WNT_FRZ_LRP6P_DVL_GSK_PhoE",0.88]
["WNT_FRZ_LRP6_DVL_GSK",0.88]
["ERBP_ERB",0.96]
["Raf**",0.97]
["WNT_FRZ_LRP6P_DVL_GSK",1.07]
["ERB",1.18]
["GSK",1.2]
["RlP_ERBP",1.27]
["Rl_ERB",1.28]
["R_ERB",1.28]
["EGF_ERB3P",1.28]
["TP53",1.38]
["ERB3_ERB",1.45]
["EGF_ERB3_ERB",1.45]
["ERB3P_Sh_G_S_Ras_GTP",2.06]
["RP_G_S_Ras_GTP",2.17]
["CDC25CP_ERBP",2.47]
["Raf*_Pase1",2.66]
["CDC25CP_Pho16",2.71]
["CDC25C_ERKPP",2.71]
["ERBP_ERBP",2.76]
["CDC25CP",2.85]
["MEKP",3.21]
["Raf*",3.52]
["ERBP_G_S_Ras",3.78]
["ERB3P_G_S_Ras_GTP",4.71]
["ERKP_Pase3",4.79]
["ERK_MEKPP",4.79]
["SOS",5.32]
["ERB_ERB",8.35]
["ERBP_ShP_G_S_Ras_GTP",10.91]
["PKP_PhoB",12.7]
["PKP",12.75]
["PKP_PIP2",13.08]
["CDC25CP_ERBP_ERBP",13.47]
["MEKPP_Pase2",18.03]
["MEKP_Raf*",18.03]
["ERKP",19.01]
["ERBP_G_S_Ras_GTP",21.18]
["Raf_Ras_GTP",44.88]
["Ras",59.31]
["MEKPP",76.8]
["G_S_ERKPP",99.52]
["SOSP_Pase5",99.77]
["SOSP",100]
["RP_ShP_G_S_ERKPP",106.86]
["Ras_GTP",118.97]
["Ras_GTP_PK",120.65]
["Ras_GTP_PKP_PhoB",166.27]
["Ras_GTP_PKP",166.84]
["Ras_GTP_PKP_PIP2",170.91]
["ERB3P_Sh_G_S_ERKPP",193.1]
["RP_ShP_G_GABP_ERKPP",196.18]
["RP_G_GABP_ERKPP",206.64]
["RP_G_S_ERKPP",259.98]
["ERB3P_ShP_G_GABP_ERKPP",353.83]
["ERB3P_G_GABP_ERKPP",372.65]
["ERB3P_G_S_ERKPP",468.64]
["GABPP",645.68]
["GABPP_PhoA",646.26]
["GABP_ERKPP",653.11]
["ERBP_ShP_G_S_ERKPP",753.3]
["ERBP_ShP_G_GABP_ERKPP",1377.93]
["ERBP_G_GABP_ERKPP",1451.07]
["ERKPP_Pase3",1555.7]
["ERKP_MEKPP",1555.7]
["ERBP_G_S_ERKPP",1824.11]
["AP1P_TFBSII",3130.2]
["AP1P_Pase12",3280.95]
["ERKPP_AP1",3280.95]
["AP1P",3366.79]
["ERKPP",5375.65]

{"sheet":"Sheet2","index":1,"n_rows":0,"n_cols":0,"rows_kept":0}

{"sheet":"Sheet3","index":2,"n_rows":0,"n_cols":0,"rows_kept":0}