Characteristics of the individuals included in the current study N = 148.

	Healthy	CRC	Pre-malignant (PM)	Diabetes Mellitus (DM)	
Total	N = 68	N = 42	N = 10	N = 28	
Tissue	N= 18	N= 18	N= 0	N= 0	
Stool	N= 50	N= 24	N= 10	N= 28	
Age (mean ± SD)	58 ± 7	62 ± 10	59 ± 7	63 ± 8	
Gender, male: n (%)	36 (23%)	23 (54%)	6 (60%)	14 (50%)	
BMI: (mean ± SD)					
Diabetes, yes: n (%)	0 (0%)	22 (52%)	4 (40%)	28 (100%)	
Hypertension, yes: n (%)	0 (0%)	23 (54%)	4 (40%)	23 (82%)	

P values of significant dysbiosis