{"text_format":"3","workbook":"xlsx","n_sheets":15,"sheets":["Supplemental Table S1","Supplemental Table S2","Supplemental Table S3","Supplemental Table S4","Supplemental Table S5","Supplemental Table S6","Supplemental Table S7","Supplemental Table S8","Supplemental Table S9","Supplemental Table S10","Supplemental Table S11","Supplemental Table S12","Supplemental Table S13","Supplemental Table 14","Supplemental Table S15"],"not_rendered":{"defined_names":10},"read":"whole","date_system":"1900"}

{"sheet":"Supplemental Table S1","index":0,"n_rows":7,"n_cols":3,"rows_kept":7}
["Suplemental Table S1 Description of the plant development phases and sampling times used in this study"]
["Months post-germination (mpg)","Phenological stage","Associated event"]
[1,"Seedlings","Plants transferred to the field"]
[3,"Pre-flowering juvenile plants","Inoculation with latex and plant material harvesting"]
[4,"Pre-flowering, young adult plants with initial floral buds","Plant material harvesting"]
[7,"Post-flowering, unripe fruits","PSD initial symptoms/ plant material harvesting"]
[9,"Post-flowering, fruit ripening","PSD evident symptoms/ plant material harvesting"]

{"sheet":"Supplemental Table S2","index":1,"n_rows":16,"n_cols":2,"rows_kept":16,"merged":[[0,0,0,1],[1,0,1,1],[8,0,8,1],[11,0,11,1]]}
["Supplemental Table S2. Term description and calculation formulas for the JIP-test. "]
["Phenomenological energy fluxes per excited cross-section (CS)"]
["ABS/CS0","Absorption energy flux per CS"]
["DI0/CS0","Dissipation energy flux per CS"]
["TR0/CS0","Trapped energy flux per CS"]
["ET0/CS0","Electron transport flux per CS"]
["RE0/CS0","Flux of reducing the terminal electron acceptor per CS"]
["RC/CS0","Density of reaction centres per CS"]
["Performance indexes"]
["PI abs","Performance index (potential) for energy conservation from photons absorbed by PSII to the reduction of intersystem electron acceptors"]
["PI total","Performance index (potential) for energy conservation from photons absorbed by PSII to the reduction of PSI end acceptors"]
["Quantum yields"]
["ϕPo/(1-ϕPo)","Quantum efficiency of primary photochemistry"]
["ψEo/(1-ψEo)","Quantum efficiency of the conversion of excitation energy to electron transport"]
["δRo/(1-δRo)","Quantum efficiency of the reduction of end acceptors"]
["γRC/(1-γRC)","QA-reducing RCs per PSII antenna Chl"]

{"sheet":"Supplemental Table S3","index":2,"n_rows":36,"n_cols":8,"rows_kept":36,"merged":[[0,0,0,7],[1,0,1,1],[2,0,7,0],[2,6,7,6],[2,7,7,7],[8,0,13,0],[8,6,13,6],[8,7,13,7],[14,0,19,0],[14,6,19,6],[14,7,19,7],[20,0,25,0],[20,6,25,6],[20,7,25,7],[26,0,26,1],[27,0,27,1],[28,0,28,7],[29,0,29,7],[30,0,30,7],[31,0,31,7],[32,0,32,7],[33,0,33,7],[34,0,34,7],[35,0,35,7]]}
["Supplemental Table S3. Proteomic coverage of PMeV+PMeV2-infected and control C. papaya leaf samples."]
["Sample",null,"MS/MS spectra1","Ions2","peptide3","Quantified proteins4","%CV\nmean","%CV\nmedian"]
["3 mpg\n(0 dpi)","C - 1",{"v":21793,"d":"21,793"},{"v":26275,"d":"26,275"},{"v":8316,"d":"8,316"},{"v":1569,"d":"1,569"},36.56,29.32]
[null,"C - 2",{"v":22608,"d":"22,608"},{"v":25928,"d":"25,928"},{"v":8317,"d":"8,317"},{"v":1580,"d":"1,580"}]
[null,"C - 3",{"v":20214,"d":"20,214"},{"v":26516,"d":"26,516"},{"v":8265,"d":"8,265"},{"v":1567,"d":"1,567"}]
[null,"I - 1",{"v":23147,"d":"23,147"},{"v":26659,"d":"26,659"},{"v":8394,"d":"8,394"},{"v":1577,"d":"1,577"}]
[null,"I - 2",{"v":24168,"d":"24,168"},{"v":27164,"d":"27,164"},{"v":8454,"d":"8,454"},{"v":1581,"d":"1,581"}]
[null,"I - 3",{"v":20299,"d":"20,299"},{"v":20532,"d":"20,532"},{"v":6205,"d":"6,205"},{"v":1262,"d":"1,262"}]
["4 mpg\n(30 dpi)","C - 1",{"v":24116,"d":"24,116"},{"v":25273,"d":"25,273"},{"v":8205,"d":"8,205"},{"v":1548,"d":"1,548"},{"v":25.6,"d":"25.60"},21.01]
[null,"C - 2",{"v":24335,"d":"24,335"},{"v":25477,"d":"25,477"},{"v":8215,"d":"8,215"},{"v":1548,"d":"1,548"}]
[null,"C - 3",{"v":14441,"d":"14,441"},{"v":25740,"d":"25,740"},{"v":8208,"d":"8,208"},{"v":1558,"d":"1,558"}]
[null,"I - 1",{"v":20785,"d":"20,785"},{"v":25136,"d":"25,136"},{"v":8079,"d":"8,079"},{"v":1532,"d":"1,532"}]
[null,"I - 2",{"v":23318,"d":"23,318"},{"v":24006,"d":"24,006"},{"v":7968,"d":"7,968"},{"v":1520,"d":"1,520"}]
[null,"I - 3",{"v":18053,"d":"18,053"},{"v":24698,"d":"24,698"},{"v":7974,"d":"7,974"},{"v":1533,"d":"1,533"}]
["7mpg\n(120 dpi)","C - 1",{"v":21007,"d":"21,007"},{"v":26204,"d":"26,204"},{"v":8287,"d":"8,287"},{"v":1568,"d":"1,568"},26.23,20.71]
[null,"C - 2",{"v":24753,"d":"24,753"},{"v":26367,"d":"26,367"},{"v":8279,"d":"8,279"},{"v":1567,"d":"1,567"}]
[null,"C - 3",{"v":24398,"d":"24,398"},{"v":25567,"d":"25,567"},{"v":8183,"d":"8,183"},{"v":1560,"d":"1,560"}]
[null,"I - 1",{"v":23163,"d":"23,163"},{"v":26481,"d":"26,481"},{"v":8279,"d":"8,279"},{"v":1567,"d":"1,567"}]
[null,"I - 2",{"v":23422,"d":"23,422"},{"v":26661,"d":"26,661"},{"v":8260,"d":"8,260"},{"v":1559,"d":"1,559"}]
[null,"I - 3",{"v":23969,"d":"23,969"},{"v":25056,"d":"25,056"},{"v":8065,"d":"8,065"},{"v":1546,"d":"1,546"}]
["9 mpg\n(180 dpi)","C - 1",{"v":21607,"d":"21,607"},{"v":25056,"d":"25,056"},{"v":8089,"d":"8,089"},{"v":1528,"d":"1,528"},26.59,21.53]
[null,"C - 2",{"v":23909,"d":"23,909"},{"v":25221,"d":"25,221"},{"v":8027,"d":"8,027"},{"v":1529,"d":"1,529"}]
[null,"C - 3",{"v":21353,"d":"21,353"},{"v":25287,"d":"25,287"},{"v":8130,"d":"8,130"},{"v":1537,"d":"1,537"}]
[null,"I - 1",{"v":23355,"d":"23,355"},{"v":26116,"d":"26,116"},{"v":8246,"d":"8,246"},{"v":1560,"d":"1,560"}]
[null,"I - 2",{"v":25465,"d":"25,465"},{"v":25153,"d":"25,153"},{"v":8057,"d":"8,057"},{"v":1519,"d":"1,519"}]
[null,"I - 3",{"v":20178,"d":"20,178"},{"v":24821,"d":"24,821"},{"v":8062,"d":"8,062"},{"v":1542,"d":"1,542"}]
["Mean",null,{"$f":"AVERAGE(C3:C26)","v":{"v":22244,"d":"22,244"}},{"$f":"AVERAGE(D3:D26)","v":{"v":25474.75,"d":"25,475"}},{"v":8106.833333333333,"d":"8,107"},{"v":1539.875,"d":"1,540"},"----","----"]
["Total",null,{"$f":"SUM(C3:C26)","v":{"v":533856,"d":"533,856"}},{"v":34624,"d":"34,624"},{"v":8979,"d":"8,979"},{"v":1609,"d":"1,609"},28.44,22.55]
["1Number of MS/MS spectra obtained using TripleTOF 5600."]
["2Number of ions extracted from MS/MS spectra using Progenesis QI for proteomics."]
["3Number of peptides identified using Mascot."]
["4Number of proteins quantified using Progenesis QI for proteomics."]
["mpg - Months post germination"]
["dpi - Days post infection"]
["C - Control"]
["I - Infected"]

{"sheet":"Supplemental Table S4","index":3,"n_rows":1641,"n_cols":78,"rows_kept":1125,"cut":true,"merged":[[1,0,4,0],[1,1,4,1],[1,2,4,2],[1,3,4,3],[1,4,4,4],[1,5,1,28],[1,29,1,52],[1,53,1,76],[1,77,4,77],[2,5,2,10],[2,11,2,16],[2,17,2,22],[2,23,2,28],[2,29,2,34],[2,35,2,40],[2,41,2,46],[2,47,2,52],[2,53,2,58],[2,59,2,64],[2,65,2,70],[2,71,2,76],[3,5,4,5],[3,6,4,6],[3,7,4,7],[3,8,4,8],[3,9,4,9],[3,10,4,10],[3,11,4,11],[3,12,4,12],[3,13,4,13],[3,14,4,14],[3,15,4,15],[3,16,4,16],[3,17,4,17],[3,18,4,18],[3,19,4,19],[3,20,4,20],[3,21,4,21],[3,22,4,22],[3,23,4,23],[3,24,4,24],[3,25,4,25],[3,26,4,26],[3,27,4,27],[3,28,4,28],[3,29,4,29],[3,30,4,30],[3,31,4,31],[3,32,4,32],[3,33,4,33],[3,34,4,34],[3,35,4,35],[3,36,4,36],[3,37,4,37],[3,38,4,38],[3,39,4,39],[3,40,4,40],[3,41,4,41],[3,42,4,42],[3,43,4,43],[3,44,4,44],[3,45,4,45],[3,46,4,46],[3,47,4,47],[3,48,4,48],[3,49,4,49],[3,50,4,50],[3,51,4,51],[3,52,4,52],[3,53,3,55],[3,56,3,58],[3,59,3,61],[3,62,3,64],[3,65,3,67],[3,68,3,70],[3,71,3,73],[3,74,3,76]],"bounds":{"rows_first":500,"rows_last":125,"rows_between":500,"halvings":2}}
["Supplemental Table S4. Compiled list of proteins identified in PMeV+PMeV2-infected and control C. papaya leaf samples."]
["Phytozome/NCBI accession1","Description2","Peptide count3","Unique peptides4","Confidence score5","Normalized abundance6",{"$nulls":23},"Raw abundance7",{"$nulls":23},"Statistics8",{"$nulls":23},"GO ID9"]
[{"$nulls":5},"3 mpg (0 dpi)",{"$nulls":5},"4 mpg (30 dpi)",{"$nulls":5},"7 mpg (120 dpi)",{"$nulls":5},"9 mpg (180 dpi)",{"$nulls":5},"3 mpg (0 dpi)",{"$nulls":5},"4 mpg (30 dpi)",{"$nulls":5},"7 mpg (120 dpi)",{"$nulls":5},"9 mpg (180 dpi)",{"$nulls":5},"3 mpg (0 dpi)",{"$nulls":5},"4 mpg (30 dpi)",{"$nulls":5},"7 mpg (120 dpi)",{"$nulls":5},"9 mpg (180 dpi)"]
[{"$nulls":5},"C-1","C-2","C-3","I-1","I-2","I-3","C-1","C-2","C-3","I-1","I-2","I-3","C-1","C-2","C-3","I-1","I-2","I-3","C-1","C-2","C-3","I-1","I-2","I-3","C-1","C-2","C-3","I-1","I-2","I-3","C-1","C-2","C-3","I-1","I-2","I-3","C-1","C-2","C-3","I-1","I-2","I-3","C-1","C-2","C-3","I-1","I-2","I-3","Control",null,null,"Infected",null,null,"Control",null,null,"Infected",null,null,"Control",null,null,"Infected",null,null,"Control",null,null,"Infected"]
[{"$nulls":53},"Mean","SD","%CV","Mean","SD","%CV","Mean","SD","%CV","Mean","SD","%CV","Mean","SD","%CV","Mean","SD","%CV","Mean","SD","%CV","Mean","SD","%CV"]
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["PACid:16417606","Nascent polypeptide-associated complex (NAC), alpha subunit family protein",6,5,302.44,{"v":718.691907255688,"d":"718.69"},{"v":1375.85670971789,"d":"1375.86"},{"v":898.327650866412,"d":"898.33"},{"v":792.387013723887,"d":"792.39"},{"v":778.018366743599,"d":"778.02"},{"v":68.0234523611167,"d":"68.02"},{"v":872.669916673386,"d":"872.67"},{"v":477.552288527058,"d":"477.55"},{"v":666.184802802749,"d":"666.18"},{"v":461.053362674381,"d":"461.05"},{"v":706.512372692466,"d":"706.51"},{"v":561.600792794942,"d":"561.60"},{"v":925.666757683188,"d":"925.67"},{"v":984.793448521747,"d":"984.79"},{"v":1187.16219499136,"d":"1187.16"},{"v":1394.30224791524,"d":"1394.30"},{"v":2070.24235280093,"d":"2070.24"},{"v":1497.55491663053,"d":"1497.55"},{"v":801.934565382899,"d":"801.93"},{"v":430.570572974458,"d":"430.57"},{"v":783.491047822569,"d":"783.49"},{"v":825.214659899729,"d":"825.21"},{"v":748.840179462575,"d":"748.84"},{"v":628.112176864752,"d":"628.11"},{"v":662.834013699438,"d":"662.83"},{"v":1226.45460661529,"d":"1226.45"},{"v":757.872980198893,"d":"757.87"},{"v":864.326715319532,"d":"864.33"},{"v":924.087758423186,"d":"924.09"},{"v":28.3718053300076,"d":"28.37"},{"v":835.775087609669,"d":"835.78"},{"v":567.109749462892,"d":"567.11"},{"v":431.151569476347,"d":"431.15"},{"v":392.95129807336,"d":"392.95"},{"v":546.708366286053,"d":"546.71"},{"v":325.628386626148,"d":"325.63"},{"v":851.834642438473,"d":"851.83"},{"v":1122.22881089482,"d":"1122.23"},{"v":1231.95570195242,"d":"1231.96"},{"v":1428.48591324943,"d":"1428.49"},{"v":1922.68182751812,"d":"1922.68"},{"v":1319.14619453232,"d":"1319.15"},{"v":588.225402766985,"d":"588.23"},{"v":516.182558494015,"d":"516.18"},{"v":624.34695916266,"d":"624.35"},{"v":720.302424274423,"d":"720.30"},{"v":897.826152323284,"d":"897.83"},{"v":470.284551120708,"d":"470.28"},{"v":997.62542261333,"d":"997.63"},{"v":277.32223135337694,"d":"277.32"},{"v":27.798232188882814,"d":"27.80"},{"v":546.1429442762009,"d":"546.14"},{"v":338.13242072287284,"d":"338.13"},{"v":61.912805844447405,"d":"61.91"},{"v":672.1356693343977,"d":"672.14"},{"v":161.36097138063468,"d":"161.36"},{"v":24.007202525113296,"d":"24.01"},{"v":576.3888427205964,"d":"576.39"},{"v":100.75232409301921,"d":"100.75"},{"v":17.479922688555362,"d":"17.48"},{"v":1032.540800398765,"d":"1032.54"},{"v":111.96673059946193,"d":"111.97"},{"v":10.843806903922887,"d":"10.84"},{"v":1654.0331724489,"d":"1654.03"},{"v":297.3077415251614,"d":"297.31"},{"v":17.974714563008348,"d":"17.97"},{"v":671.9987287266421,"d":"672.00"},{"v":170.88145330886593,"d":"170.88"},{"v":25.428835800428672,"d":"25.43"},{"v":734.0556720756853,"d":"734.06"},{"v":81.14301550818925,"d":"81.14"},{"v":11.054068321376985,"d":"11.05"},"------"]
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["PACid:16417947","Glutathione S-transferase, C-terminal-like",6,5,212.52,"------","------","------","------","------","------","------","------","------","------","------","------","------","------","------","------","------","------","------","------","------","------","------","------","------","------","------","------","------","------","------","------","------","------","------","------","------","------","------","------","------","------","------","------","------","------","------","------","------","------","------","------","------","------","------","------","------","------","------","------","------","------","------","------","------","------","------","------","------","------","------","------","5829, 5794, 8135, 43234, 5576, 5773, 5886, 6950"]
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["PACid:16432165","Aldolase-type TIM barrel family protein",1,1,39.79,{"v":171.257327604933,"d":"171.26"},{"v":214.475606206828,"d":"214.48"},{"v":329.281406750384,"d":"329.28"},{"v":237.316712390881,"d":"237.32"},{"v":222.690819926811,"d":"222.69"},{"v":233.297844697316,"d":"233.30"},{"v":836.762175670523,"d":"836.76"},{"v":148.446392782076,"d":"148.45"},{"v":146.910516848583,"d":"146.91"},{"v":117.766181940826,"d":"117.77"},{"v":116.648958421028,"d":"116.65"},{"v":70.0764195622416,"d":"70.08"},{"v":193.130842123924,"d":"193.13"},{"v":292.327962568771,"d":"292.33"},{"v":437.464812319612,"d":"437.46"},{"v":239.886150874376,"d":"239.89"},{"v":355.352029990179,"d":"355.35"},{"v":134.087167552738,"d":"134.09"},{"v":114.632720078654,"d":"114.63"},{"v":102.601922335017,"d":"102.60"},{"v":207.54195078727,"d":"207.54"},{"v":186.786532473253,"d":"186.79"},{"v":81.3396502565211,"d":"81.34"},{"v":82.7111163728508,"d":"82.71"},{"v":157.946932038337,"d":"157.95"},{"v":191.186039491647,"d":"191.19"},{"v":277.797840038999,"d":"277.80"},{"v":258.862362656937,"d":"258.86"},{"v":264.500003346844,"d":"264.50"},{"v":97.3058673723855,"d":"97.31"},{"v":801.385457797592,"d":"801.39"},{"v":176.28519146871,"d":"176.29"},{"v":95.0797731280618,"d":"95.08"},{"v":100.370971798928,"d":"100.37"},{"v":90.2644652128252,"d":"90.26"},{"v":40.6318362355333,"d":"40.63"},{"v":177.72653115062,"d":"177.73"},{"v":333.124537249207,"d":"333.12"},{"v":453.97105148266,"d":"453.97"},{"v":245.767363439339,"d":"245.77"},{"v":330.023627190032,"d":"330.02"},{"v":118.112915158256,"d":"118.11"},{"v":84.0840148925939,"d":"84.08"},{"v":123.002652994669,"d":"123.00"},{"v":165.385662328669,"d":"165.39"},{"v":163.039750382822,"d":"163.04"},{"v":97.5226319633985,"d":"97.52"},{"v":61.9280467228937,"d":"61.93"},{"v":238.33811352071498,"d":"238.34"},{"v":66.68316548635512,"d":"66.68"},{"v":27.978389398705804,"d":"27.98"},{"v":231.10179233833603,"d":"231.10"},{"v":6.169611930809002,"d":"6.17"},{"v":2.6696512685529545,"d":"2.67"},{"v":377.3730284337273,"d":"377.37"},{"v":324.8377863672201,"d":"324.84"},{"v":86.07869717543069,"d":"86.08"},{"v":101.4971866413652,"d":"101.50"},{"v":22.22251860881506,"d":"22.22"},{"v":21.894713877476352,"d":"21.89"},{"v":307.641205670769,"d":"307.64"},{"v":100.33491851003323,"d":"100.33"},{"v":32.61426514412036,"d":"32.61"},{"v":243.10844947243103,"d":"243.11"},{"v":90.35973381824519,"d":"90.36"},{"v":37.168487567723204,"d":"37.17"},{"v":141.592197733647,"d":"141.59"},{"v":46.89145245111292,"d":"46.89"},{"v":33.11725730772378,"d":"33.12"},{"v":116.94576636754164,"d":"116.95"},{"v":49.38805312692246,"d":"49.39"},{"v":42.231587051816646,"d":"42.23"},"44281, 16491, 43167, 34641, 9058"]
["PACid:16432172","O-fucosyltransferase family protein",1,1,36.48,{"v":187.145517725412,"d":"187.15"},{"v":251.93837762406,"d":"251.94"},{"v":288.757911179611,"d":"288.76"},{"v":235.115879626826,"d":"235.12"},{"v":255.509500332422,"d":"255.51"},{"v":119.459138706663,"d":"119.46"},{"v":196.549873628725,"d":"196.55"},{"v":183.093420251897,"d":"183.09"},{"v":170.731130852531,"d":"170.73"},{"v":136.954914560844,"d":"136.95"},{"v":105.327853222066,"d":"105.33"},{"v":117.992851433926,"d":"117.99"},{"v":191.462985637513,"d":"191.46"},{"v":252.907488475416,"d":"252.91"},{"v":262.044822001793,"d":"262.04"},{"v":288.52483683736,"d":"288.52"},{"v":294.847411573014,"d":"294.85"},{"v":230.988459489559,"d":"230.99"},{"v":123.853473134958,"d":"123.85"},{"v":81.4973042177154,"d":"81.50"},{"v":181.270234366546,"d":"181.27"},{"v":192.889419029413,"d":"192.89"},{"v":137.358459664111,"d":"137.36"},{"v":145.107767364941,"d":"145.11"},{"v":172.600266411046,"d":"172.60"},{"v":224.580787837687,"d":"224.58"},{"v":243.610244536759,"d":"243.61"},{"v":256.461719384172,"d":"256.46"},{"v":303.480240969464,"d":"303.48"},{"v":49.8250428438001,"d":"49.83"},{"v":188.240117727352,"d":"188.24"},{"v":217.429726926068,"d":"217.43"},{"v":110.496358841941,"d":"110.50"},{"v":116.725342034254,"d":"116.73"},{"v":81.5040483155387,"d":"81.50"},{"v":68.4148283598973,"d":"68.41"},{"v":176.19170458161,"d":"176.19"},{"v":288.20263831385,"d":"288.20"},{"v":271.932187526039,"d":"271.93"},{"v":295.598508616772,"d":"295.60"},{"v":273.83159240038,"d":"273.83"},{"v":203.470032339195,"d":"203.47"},{"v":90.8475108366421,"d":"90.85"},{"v":97.7017233455036,"d":"97.70"},{"v":144.450303456544,"d":"144.45"},{"v":168.366757033441,"d":"168.37"},{"v":164.686699126893,"d":"164.69"},{"v":108.646104554098,"d":"108.65"},{"v":242.61393550969433,"d":"242.61"},{"v":42.00379777616021,"d":"42.00"},{"v":17.31301942236613,"d":"17.31"},{"v":203.36150622197033,"d":"203.36"},{"v":59.90926693690615,"d":"59.91"},{"v":29.459492137865475,"d":"29.46"},{"v":183.45814157771767,"d":"183.46"},{"v":10.54361215365173,"d":"10.54"},{"v":5.747148675429693,"d":"5.75"},{"v":120.09187307227869,"d":"120.09"},{"v":12.996721922864582,"d":"13.00"},{"v":10.82231594059854,"d":"10.82"},{"v":235.47176537157398,"d":"235.47"},{"v":31.341689342406596,"d":"31.34"},{"v":13.310168755455445,"d":"13.31"},{"v":271.4535692999777,"d":"271.45"},{"v":28.72934123619888,"d":"28.73"},{"v":10.583519424808403,"d":"10.58"},{"v":128.87367057307313,"d":"128.87"},{"v":40.886519248273046,"d":"40.89"},{"v":31.726045410563387,"d":"31.73"},{"v":158.45188201948835,"d":"158.45"},{"v":24.555663419300807,"d":"24.56"},{"v":15.49723683072483,"d":"15.50"},"------"]
["PACid:16432275","None",1,1,13.04,{"v":16.48322044317,"d":"16.48"},{"v":73.826794787603,"d":"73.83"},{"v":62.0889394024854,"d":"62.09"},{"v":28.7452126467288,"d":"28.75"},{"v":12.8853759136913,"d":"12.89"},{"v":0,"d":"0.00"},{"v":18.4613416966868,"d":"18.46"},{"v":6.624602648099,"d":"6.62"},{"v":28.4164011418303,"d":"28.42"},{"v":7.48113487562287,"d":"7.48"},{"v":18.0393432083388,"d":"18.04"},{"v":12.8124328720295,"d":"12.81"},{"v":46.5418840735869,"d":"46.54"},{"v":124.271473144265,"d":"124.27"},{"v":173.491345018039,"d":"173.49"},{"v":54.2722089338231,"d":"54.27"},{"v":146.83341103459,"d":"146.83"},{"v":190.041350504828,"d":"190.04"},{"v":20.3693777111374,"d":"20.37"},{"v":14.637406261367,"d":"14.64"},{"v":17.7846627580087,"d":"17.78"},{"v":32.2428806663082,"d":"32.24"},{"v":17.7663928635771,"d":"17.77"},{"v":0,"d":"0.00"},{"v":15.2021179795364,"d":"15.20"},{"v":65.8100599570889,"d":"65.81"},{"v":52.3812547648582,"d":"52.38"},{"v":31.3549500405696,"d":"31.35"},{"v":15.3045463365612,"d":"15.30"},{"v":0,"d":"0.00"},{"v":17.6808311815741,"d":"17.68"},{"v":7.86694324016787,"d":"7.87"},{"v":18.3909568330355,"d":"18.39"},{"v":6.37609851359889,"d":"6.38"},{"v":13.9590759277434,"d":"13.96"},{"v":7.42892798300974,"d":"7.43"},{"v":42.8296564062266,"d":"42.83"},{"v":141.614495653051,"d":"141.61"},{"v":180.037447819776,"d":"180.04"},{"v":55.6027834415489,"d":"55.60"},{"v":136.367575847701,"d":"136.37"},{"v":167.401089294461,"d":"167.40"},{"v":14.9411010891215,"d":"14.94"},{"v":17.5478174495611,"d":"17.55"},{"v":14.1722105741414,"d":"14.17"},{"v":28.1437379122115,"d":"28.14"},{"v":21.3011168241761,"d":"21.30"},{"v":0,"d":"0.00"},{"v":50.79965154441947,"d":"50.80"},{"v":24.734016992872863,"d":"24.73"},{"v":48.689343806315904,"d":"48.69"},{"v":13.876862853473368,"d":"13.88"},{"v":11.756107555656142,"d":"11.76"},{"v":84.71732897982484,"d":"84.72"},{"v":17.834115162205368,"d":"17.83"},{"v":8.907512942904459,"d":"8.91"},{"v":49.94648101062815,"d":"49.95"},{"v":12.777636985330389,"d":"12.78"},{"v":4.3104407249186965,"d":"4.31"},{"v":33.73425563636986,"d":"33.73"},{"v":114.7682340786303,"d":"114.77"},{"v":52.260725043291025,"d":"52.26"},{"v":45.53587973435753,"d":"45.54"},{"v":130.38232349108037,"d":"130.38"},{"v":56.63505193638217,"d":"56.64"},{"v":43.437676534623684,"d":"43.44"},{"v":17.597148910171033,"d":"17.60"},{"v":2.343820991115984,"d":"2.34"},{"v":13.319322369098504,"d":"13.32"},{"v":16.669757843295102,"d":"16.67"},{"v":13.18592165129738,"d":"13.19"},{"v":79.10085902418199,"d":"79.10"},"------"]
["1Phytozome or NCBI gene identification number."]
["2Phytozome or NCBI gene description."]
["3Number of peptides identified using Progenesis QI for proteomics."]
["4Number of peptides attributed to only one proteins (non-conflicting peptides)."]
["5Quality assurance scores for protein alignment by Progenesis QI."]
["6Normalized protein abundances."]
["7Raw protein abundances."]
["8Statistics"]
["9Gene Ontology identification number."]
["mpg - months post germination"]
["dpi - days post inoculation"]
["SD - Standard Deviation"]
["CV - Coefficient of Variation"]

{"sheet":"Supplemental Table S5","index":4,"n_rows":9057,"n_cols":60,"rows_kept":1125,"cut":true,"merged":[[1,0,3,0],[1,1,3,1],[1,2,3,2],[1,3,3,3],[1,4,3,4],[1,5,3,5],[1,6,3,6],[1,7,1,30],[1,31,1,54],[1,55,3,55],[1,56,3,56],[1,57,3,57],[1,58,3,58],[1,59,3,59],[2,7,2,12],[2,13,2,18],[2,19,2,24],[2,25,2,30],[2,31,2,36],[2,37,2,42],[2,43,2,48],[2,49,2,54]],"bounds":{"rows_first":500,"rows_last":125,"rows_between":500,"halvings":2}}
["Supplemental Table S5. Peptides identified from PMeV+PMeV2-infected C. papaya leaf samples."]
["Ion ID1","Retention time (min)2","Charge3","m/z4","Mass5","Use in quantitation6","Anova7","Normalized abundance8",{"$nulls":23},"Spectral counts9",{"$nulls":23},"Score10","Phytozome/NCBI Accession11","Description12","Sequence13","Modifications14"]
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["1Ion ID."]
["2Retention time (min)."]
["3Charge."]
["4m/z."]
["5Mass."]
["6Use in quantitation."]
["7Anova."]
["8Normalized abundance (H-healthy, I-Infected)."]
["9Spectral counts."]
["10Best peptide match score."]
["11Phytozome or NCBI gene ID."]
["12Phytozome or NCBI description."]
["13Sequence."]
["14Modifications."]
["mpg - months post germination"]
["dpi - days post inoculation"]

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["Supplemental Table S6. Label-free proteomics LC-MS/MS ions in PMeV+PMeV2-infected C. papaya leaf."]
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[34624,{"v":494.267984856392,"d":"494.26798"},{"v":38.8881666666667,"d":"38.89"},{"v":1479.78212516854,"d":"1479.78"},3,{"v":0.802408224568779,"d":"0.802"},{"v":8.27924232944986,"d":"8.28"},{"v":2.67013359251676,"d":"2.67"},{"v":4.7629414586297,"d":"4.76"},{"v":0.502042911422221,"d":"0.50"},{"v":2.4320374576087,"d":"2.43"},{"v":1.50532385618341,"d":"1.51"},{"v":2.69295459030691,"d":"2.69"},{"v":4.31691290513728,"d":"4.32"},{"v":2.14407399360086,"d":"2.14"},{"v":7.28842163919174,"d":"7.29"},{"v":2.11766136711527,"d":"2.12"},{"v":4.12503401461428,"d":"4.13"},{"v":2.60651920133599,"d":"2.61"},{"v":4.46659025489077,"d":"4.47"},{"v":6.55957393431895,"d":"6.56"},{"v":3.46740945626812,"d":"3.47"},{"v":2.68514239974168,"d":"2.69"},{"v":1.01918503233483,"d":"1.02"},{"v":5.81188158134954,"d":"5.81"},{"v":5.22552939701751,"d":"5.23"},{"v":1.51293810835181,"d":"1.51"},{"v":0.719038185251756,"d":"0.72"},{"v":1.92270576320326,"d":"1.92"},{"v":3.73911073395983,"d":"3.74"},{"v":48,"d":"48.00"},{"v":32,"d":"32.00"},{"v":28,"d":"28.00"},{"v":25,"d":"25.00"},{"v":40,"d":"40.00"},{"v":19,"d":"19.00"},{"v":32,"d":"32.00"},{"v":36,"d":"36.00"},{"v":24,"d":"24.00"},{"v":32,"d":"32.00"},{"v":20,"d":"20.00"},{"v":24,"d":"24.00"},{"v":28,"d":"28.00"},{"v":32,"d":"32.00"},{"v":32,"d":"32.00"},{"v":36,"d":"36.00"},{"v":28,"d":"28.00"},{"v":28,"d":"28.00"},{"v":24,"d":"24.00"},{"v":40,"d":"40.00"},{"v":20,"d":"20.00"},{"v":24,"d":"24.00"},{"v":44,"d":"44.00"},{"v":24,"d":"24.00"}]
[34625,{"v":758.362872171848,"d":"758.36287"},{"v":40.2002,"d":"40.20"},{"v":1514.71119140994,"d":"1514.71"},2,{"v":0.462507502000268,"d":"0.463"},{"v":0.674890067391849,"d":"0.67"},{"v":0.934892506551205,"d":"0.93"},{"v":0,"d":"0.00"},{"v":0,"d":"0.00"},{"v":0.80773754375876,"d":"0.81"},{"v":172.181875087492,"d":"172.18"},{"v":4.83468068639243,"d":"4.83"},{"v":0,"d":"0.00"},{"v":0,"d":"0.00"},{"v":0,"d":"0.00"},{"v":0,"d":"0.00"},{"v":0.335585995032754,"d":"0.34"},{"v":0.803332433420441,"d":"0.80"},{"v":2.02779667657605,"d":"2.03"},{"v":0.209737634562418,"d":"0.21"},{"v":0.729073772095949,"d":"0.73"},{"v":0.226074860138134,"d":"0.23"},{"v":0,"d":"0.00"},{"v":2.02616208162657,"d":"2.03"},{"v":0,"d":"0.00"},{"v":0,"d":"0.00"},{"v":0.160267968549745,"d":"0.16"},{"v":0.755408004863951,"d":"0.76"},{"v":0,"d":"0.00"},{"v":20,"d":"20.00"},{"v":32,"d":"32.00"},{"v":0,"d":"0.00"},{"v":0,"d":"0.00"},{"v":19,"d":"19.00"},{"v":185,"d":"185.00"},{"v":64,"d":"64.00"},{"v":0,"d":"0.00"},{"v":0,"d":"0.00"},{"v":0,"d":"0.00"},{"v":0,"d":"0.00"},{"v":12,"d":"12.00"},{"v":20,"d":"20.00"},{"v":24,"d":"24.00"},{"v":16,"d":"16.00"},{"v":16,"d":"16.00"},{"v":16,"d":"16.00"},{"v":0,"d":"0.00"},{"v":40,"d":"40.00"},{"v":0,"d":"0.00"},{"v":0,"d":"0.00"},{"v":8,"d":"8.00"},{"v":28,"d":"28.00"},{"v":0,"d":"0.00"}]
[34626,{"v":381.865902529385,"d":"381.86590"},{"v":28.6684833333333,"d":"28.67"},{"v":1142.57587818752,"d":"1142.58"},3,{"v":0.893460897168616,"d":"0.893"},{"v":3.20934529434529,"d":"3.21"},{"v":0.284881825767165,"d":"0.28"},{"v":0.0222545822637054,"d":"0.02"},{"v":0.0915071575968112,"d":"0.09"},{"v":0.604010588104702,"d":"0.60"},{"v":0,"d":"0.00"},{"v":0.0566754315336685,"d":"0.06"},{"v":0.0921136032215384,"d":"0.09"},{"v":1.55015916006021,"d":"1.55"},{"v":0.0183799144720767,"d":"0.02"},{"v":0.0987158793087987,"d":"0.10"},{"v":0.67137868033703,"d":"0.67"},{"v":0.717122664911383,"d":"0.72"},{"v":0.0492101299045932,"d":"0.05"},{"v":0.0212761794803064,"d":"0.02"},{"v":1.31215057059728,"d":"1.31"},{"v":0.448259468912428,"d":"0.45"},{"v":0.000150104656670352,"d":"0.00"},{"v":0.834828168290141,"d":"0.83"},{"v":0.133575161033818,"d":"0.13"},{"v":0.0479162931819646,"d":"0.05"},{"v":1.06788365694588,"d":"1.07"},{"v":1.41645019086647,"d":"1.42"},{"v":0.0238467912024278,"d":"0.02"},{"v":40,"d":"40.00"},{"v":8,"d":"8.00"},{"v":4,"d":"4.00"},{"v":8,"d":"8.00"},{"v":20,"d":"20.00"},{"v":0,"d":"0.00"},{"v":4,"d":"4.00"},{"v":4,"d":"4.00"},{"v":20,"d":"20.00"},{"v":1.1488185822509,"d":"1.15"},{"v":3.64619894657153,"d":"3.65"},{"v":12,"d":"12.00"},{"v":12,"d":"12.00"},{"v":4,"d":"4.00"},{"v":2.91190987105074,"d":"2.91"},{"v":20,"d":"20.00"},{"v":8,"d":"8.00"},{"v":0.101779230068132,"d":"0.10"},{"v":16.0000000002328,"d":"16.00"},{"v":8,"d":"8.00"},{"v":4,"d":"4.00"},{"v":8,"d":"8.00"},{"v":20,"d":"20.00"},{"v":4,"d":"4.00"}]
["1Ion ID."]
["2m/z."]
["3Retention time (min)."]
["4Mass."]
["5Charge."]
["6Anova."]
["7Normalized abundance (H-healthy, I-Infected)."]
["8Intensity."]
["9Best peptide spectral counts."]
["10Best paptide match score."]
["11Sequence."]
["12Variable modifications ([position] description)."]
["13Phytozome or NCBI gene ID."]
["14Phytozome or NCBI description."]
["mpg - months post germination"]
["dpi - days post inoculation"]

{"sheet":"Supplemental Table S7","index":6,"n_rows":47,"n_cols":5,"rows_kept":47,"merged":[[0,0,0,4],[2,0,2,4],[15,0,15,4],[42,0,42,4],[43,0,43,4],[44,0,44,4],[45,0,45,4],[46,0,46,4]]}
["Supplemental Table S7. Proteins differently modulated in 3 months post germination (0 days post inoculation) PMeV+PMeV2-infected C. papaya leaf."]
["Phytozome/NCBI Accession1","Description2","Confidence score3","Anova (p)4","FC5"]
["Up-accumulated proteins"]
["PACid:16409811","lipid transfer protein 4",20.88,{"v":5.11611192502981e-05,"d":"0.000"},{"v":6.171384975977579,"d":"6.17"}]
["PACid:16408331","AMP-dependent synthetase and ligase family protein",39.4,{"v":0.0293325049057371,"d":"0.029"},{"v":4.1251230717923635,"d":"4.13"}]
["PACid:16415201","plastocyanin 1",177.86,{"v":6.54776526434198E-5,"d":"0.000"},{"v":3.4628220088127173,"d":"3.46"}]
["PACid:16405411","acyl-activating enzyme 7",35.54,{"v":0.0439543862928179,"d":"0.044"},{"v":3.4046389233474113,"d":"3.40"}]
["PACid:16425995","methyl esterase 10",13.16,{"v":0.0387753729173004,"d":"0.039"},{"v":3.1700421196578907,"d":"3.17"}]
["GI:167391859","photosystem I subunit VII (chloroplast) [Carica papaya]",87.72,{"v":0.00224807519279657,"d":"0.002"},{"v":3.160655744572045,"d":"3.16"}]
["PACid:16424915","beta carbonic anhydrase 4",44.03,{"v":1.91113808032151E-3,"d":"0.002"},{"v":2.572338752364859,"d":"2.57"}]
["PACid:16429310","Transketolase family protein",40.95,{"v":0.020010380959686,"d":"0.020"},{"v":2.0393467626133686,"d":"2.04"}]
["PACid:16411634","chitinase A",138.06,{"v":0.0088876410572446,"d":"0.009"},{"v":1.7303811157474493,"d":"1.73"}]
["PACid:16413598","Ribosomal protein S11 family protein",51.01,{"v":0.00436106486569587,"d":"0.004"},{"v":1.6195420209043403,"d":"1.62"}]
["PACid:16417715","alanine-2-oxoglutarate aminotransferase 2",525.52,{"v":0.039439147877786,"d":"0.039"},{"v":1.2463916079385804,"d":"1.25"}]
["GI:167391794","ribosomal protein S2 (chloroplast) [Carica papaya]",59.66,{"v":0.0219338272222366,"d":"0.022"},{"v":1.2114475334876902,"d":"1.21"}]
["Down-accumulated proteins"]
["PACid:16422371","uricase / urate oxidase / nodulin 35, putative",19.62,{"v":0.0398733701835458,"d":"0.040"},"-∞"]
["PACid:16427270","Calcium-dependent lipid-binding (CaLB domain) plant phosphoribosyltransferase family protein",43.17,{"v":4.75111421636143e-05,"d":"0.000"},"-∞"]
["PACid:16412656","eukaryotic translation initiation factor 2 beta subunit",41.82,{"v":0.0342217386838303,"d":"0.034"},{"v":-3.307602116952963,"d":"-3.31"}]
["PACid:16429295","glucose-6-phosphate dehydrogenase 2",14.94,{"v":0.0452158836746823,"d":"0.045"},{"v":-2.183618277654875,"d":"-2.18"}]
["PACid:16427157","methionine--tRNA ligase, putative / methionyl-tRNA synthetase, putative / MetRS, putative",45.42,{"v":0.0496603922327952,"d":"0.050"},{"v":-2.1625512227556833,"d":"-2.16"}]
["PACid:16418818","D-3-phosphoglycerate dehydrogenase",103.61,{"v":3.83008536297735E-3,"d":"0.004"},{"v":-1.651697655769041,"d":"-1.65"}]
["PACid:16412697","Alba DNA/RNA-binding protein",56.52,{"v":0.0403022080205032,"d":"0.040"},{"v":-1.4759432424429348,"d":"-1.48"}]
["PACid:16414081","ubiquitin-specific protease 21",24.89,{"v":0.0261911663081167,"d":"0.026"},{"v":-1.3873613124182556,"d":"-1.39"}]
["PACid:16414897","phospholipid:diacylglycerol acyltransferase",43.1,{"v":0.0494610946509844,"d":"0.049"},{"v":-1.377847696584889,"d":"-1.38"}]
["PACid:16407009","UDP-glucosyl transferase 74D1",68.07,{"v":0.0117982634216813,"d":"0.012"},{"v":-1.3662772394829716,"d":"-1.37"}]
["PACid:16424332","Sec23/Sec24 protein transport family protein",43.77,{"v":0.0324327505036455,"d":"0.032"},{"v":-1.2729514874936287,"d":"-1.27"}]
["PACid:16427781","NAD(P)-binding Rossmann-fold superfamily protein",90.42,{"v":0.0333882937458027,"d":"0.033"},{"v":-1.0941998266860018,"d":"-1.09"}]
["PACid:16408289","Single hybrid motif superfamily protein",42.34,{"v":0.0209177952381669,"d":"0.021"},{"v":-1.0909590955577304,"d":"-1.09"}]
["PACid:16412334","annexin 8",127.72,{"v":0.0396924368339451,"d":"0.040"},{"v":-1.0164935913696955,"d":"-1.02"}]
["PACid:16411621","basic chitinase",87.11,{"v":0.0216961116440096,"d":"0.022"},{"v":-0.9702551299377481,"d":"-0.97"}]
["PACid:16408656","Glycosyl transferase, family 35",282.94,{"v":0.000469013422005449,"d":"0.000"},{"v":-0.9390836985407004,"d":"-0.94"}]
["PACid:16406935","ubiquitin family protein",14.98,{"v":0.0422484103735171,"d":"0.042"},{"v":-0.9361358303161627,"d":"-0.94"}]
["PACid:16425142","sodium/calcium exchanger family protein / calcium-binding EF hand family protein",42.94,{"v":0.0175194681624522,"d":"0.018"},{"v":-0.9360633741026748,"d":"-0.94"}]
["PACid:16411567","Calcium-binding EF-hand family protein",154.18,{"v":0.0163300290168591,"d":"0.016"},{"v":-0.9098587840959159,"d":"-0.91"}]
["PACid:16425236","sequence-specific DNA binding transcription factors",14.13,{"v":0.0160546782010599,"d":"0.016"},{"v":-0.8708542759492839,"d":"-0.87"}]
["PACid:16427718","HAD superfamily, subfamily IIIB acid phosphatase ",94.1,{"v":0.0339590352544472,"d":"0.034"},{"v":-0.8398953084735682,"d":"-0.84"}]
["PACid:16408599","elongation factor Ts family protein",196.44,{"v":0.0478091548120028,"d":"0.048"},{"v":-0.8321113339110954,"d":"-0.83"}]
["PACid:16418358","general regulatory factor 2",482.89,{"v":0.0304252466585037,"d":"0.030"},{"v":-0.7721306312114816,"d":"-0.77"}]
["PACid:16404978","Glycosyl hydrolase family protein",288.12,{"v":0.0246762388187677,"d":"0.025"},{"v":-0.7495487940206012,"d":"-0.75"}]
["PACid:16403907","structural constituent of ribosome",119.06,{"v":0.0199827330075969,"d":"0.020"},{"v":-0.6447174176333605,"d":"-0.64"}]
["PACid:16423886","Ribosomal L29 family protein ",89.28,{"v":0.00410031746487072,"d":"0.004"},{"v":-0.6119112313842061,"d":"-0.61"}]
["1Phytozome or NCBI gene identification number."]
["2Phytozome or NCBI gene description."]
["3Quality assurance scores for protein alignment by Progenesis QI."]
["4Analysis of variance (ANOVA) based p value (p≤0.05)."]
["5Log2 fold change of protein abundances comparing PMeV+PMeV2-infected vs. control plants."]

{"sheet":"Supplemental Table S8","index":7,"n_rows":37,"n_cols":9,"rows_kept":37,"merged":[[2,0,2,8],[4,0,4,8],[20,0,20,8],[25,0,25,8]]}
["Supplemental Table S8 Gene Ontology terms enrichment analyses of up- vs. down-accumulated PMeV+PMeV2-infected C. papaya modulated proteins."]
["GO Number1","GO Term2","GO Group3","No Down-reg4","Enrichment Down-reg (%)5","No Up-reg6","Enrichment     Up-reg (%)7 ","FDR8","P-Value9"]
["3 months post germination (0 dpi)"]
["There are no statistically significant results",null,"----","----","----","----","----","----","----"]
["4 months post germination (30 dpi)"]
["GO:0009579","thylakoid","C",1,{"v":4.166666666666666,"d":"4.17"},23,{"v":95.83333333333334,"d":"95.83"},{"v":7.37289e-06,"d":"7.37E-06"},{"v":6.068222e-08,"d":"6.07E-08"}]
["GO:0015979","photosynthesis","P",1,{"v":4.761904761904762,"d":"4.76"},20,{"v":95.23809523809523,"d":"95.24"},{"v":7.723872e-05,"d":"7.72E-05"},{"v":9.535644E-7,"d":"9.54E-07"}]
["GO:0006091","generation of precursor metabolites and energy","P",2,{"v":11.11111111111111,"d":"11.11"},16,{"v":88.88888888888889,"d":"88.89"},{"v":0.0115123,"d":"1.15E-02"},{"v":0.0001895029,"d":"1.90E-04"}]
["GO:0009536","plastid","C",7,{"v":16.666666666666664,"d":"16.67"},35,{"v":83.33333333333334,"d":"83.33"},{"v":3.634756E-6,"d":"3.63E-06"},{"v":1.495784e-08,"d":"1.50E-08"}]
["GO:0016491","oxidoreductase activity","F",4,{"v":21.052631578947366,"d":"21.05"},15,{"v":78.94736842105263,"d":"78.95"},{"v":0.1779467,"d":"1.78E-01"},{"v":5.126037E-3,"d":"5.13E-03"}]
["GO:0044281","small molecule metabolic process","P",13,{"v":34.21052631578947,"d":"34.21"},25,{"v":65.78947368421053,"d":"65.79"},{"v":0.3298476,"d":"3.30E-01"},{"v":0.01128029,"d":"1.13E-02"}]
["GO:0044710","single-organism metabolic process","P",15,{"v":35.714285714285715,"d":"35.71"},27,{"v":64.28571428571429,"d":"64.29"},{"v":0.3298476,"d":"3.30E-01"},{"v":0.01346301,"d":"1.35E-02"}]
["GO:0044237","cellular metabolic process","P",26,{"v":41.269841269841265,"d":"41.27"},37,{"v":58.730158730158735,"d":"58.73"},{"v":0.4425923,"d":"4.43E-01"},{"v":0.02003504,"d":"2.00E-02"}]
["GO:0005773","vacuole","C",7,{"v":100,"d":"100.00"},0,{"v":0,"d":"0.00"},{"v":0.3298476,"d":"3.30E-01"},{"v":0.01357398,"d":"1.36E-02"}]
["GO:0005783","endoplasmic reticulum","C",6,{"v":100,"d":"100.00"},0,{"v":0,"d":"0.00"},{"v":0.4909039,"d":"4.91E-01"},{"v":0.02828253,"d":"2.83E-02"}]
["GO:0003723","RNA binding","F",6,{"v":100,"d":"100.00"},0,{"v":0,"d":"0.00"},{"v":0.4909039,"d":"4.91E-01"},{"v":0.02828253,"d":"2.83E-02"}]
["GO:0012505","endomembrane system","C",12,{"v":92.3076923076923,"d":"92.31"},1,{"v":7.6923076923076925,"d":"7.69"},{"v":0.09368821,"d":"9.37E-02"},{"v":0.002313289,"d":"2.31E-03"}]
["GO:0005829","cytosol","C",16,{"v":88.88888888888889,"d":"88.89"},2,{"v":11.11111111111111,"d":"11.11"},{"v":0.03246157,"d":"3.25E-02"},{"v":0.0006679335,"d":"6.68E-04"}]
["GO:0009056","catabolic process","P",19,{"v":73.07692307692307,"d":"73.08"},7,{"v":26.923076923076923,"d":"26.92"},{"v":0.4909039,"d":"4.91E-01"},{"v":0.02617355,"d":"2.62E-02"}]
["GO:0016787","hydrolase activity","F",21,{"v":70,"d":"70.00"},9,{"v":30,"d":"30.00"},{"v":0.5698722,"d":"5.70E-01"},{"v":0.0351773,"d":"3.52E-02"}]
["7 months post germination (120 dpi)"]
["GO:0009536","plastid","C",6,{"v":19.35483870967742,"d":"19.35"},25,{"v":80.64516129032258,"d":"80.65"},{"v":0.8438064,"d":"8.44E-01"},{"v":0.01059171,"d":"1.06E-02"}]
["GO:0006091","generation of precursor metabolites and energy","P",4,{"v":23.52941176470588,"d":"23.53"},13,{"v":76.47058823529412,"d":"76.47"},{"v":1,"d":"1.00E+00"},{"v":0.02302449,"d":"2.30E-02"}]
["GO:0009579","thylakoid","C",4,{"v":50,"d":"50.00"},4,{"v":50,"d":"50.00"},{"v":0.1164053,"d":"1.16E-01"},{"v":0.0009741028,"d":"9.74E-04"}]
["GO:0015979","photosynthesis","P",5,{"v":62.5,"d":"62.50"},3,{"v":37.5,"d":"37.50"},{"v":0.009402683,"d":"9.40E-03"},{"v":3.934177e-05,"d":"3.93E-05"}]
["9 months post germination (180 dpi)"]
["There are no statistically significant results",null,"----","----","----","----","----","----","----"]
["1Gene ontology (GO) Identifier."]
["2Gene ontology term description."]
["3Gene ontology category. P: biological process, F: molecular function and C: cellular component."]
["4Number of down-regulated sequences assigned to the GO term."]
["5Percentage of  GO term enriched in down-regulated sequences."]
["6Number of up-regulated sequences assigned to the GO term."]
["7Percentage of GO term enriched in up-regulated."]
["8False discovery rate (FDR).  "]
["9P-value from Fisher's exact test using a cutoff ≤ 0.05.  "]
["dpi - days post inoculation"]

{"sheet":"Supplemental Table S9","index":8,"n_rows":60,"n_cols":5,"rows_kept":60,"merged":[[2,0,2,4],[5,0,5,4],[7,0,7,4],[9,0,9,4],[12,0,12,4],[14,0,14,4],[19,0,19,4],[22,0,22,4],[25,0,25,4],[27,0,27,4],[32,0,32,4],[35,0,35,4],[45,0,45,4],[49,0,49,4],[51,0,51,4],[53,0,53,4],[54,0,54,4],[55,0,55,4],[56,0,56,4],[57,0,57,4],[58,0,58,4],[59,0,59,4]]}
["Supplemental Table S9. Metabolic pathway overview of abundance changed proteins in 3 months post germination (0 days post inoculation) PMeV+PMeV2-infected and control C. papaya leaf samples."]
["Bin Code1","Bin Name2","Protein ID3","Protein Description4","FC5"]
["Photosynthesis"]
["1.1.5.1","PS.lightreaction.other electron carrier (ox/red).plastocyanin","PACid:16415201","plastocyanin 1",3.463]
["1.2.4.4","PS.photorespiration.glycine cleavage.H protein","PACid:16408289","Single hybrid motif superfamily protein/ GLYCINE CLEAVAGE SYSTEM H PROTEIN",-1.091]
["Major carbohydrates"]
["2.2.2.2","major CHO metabolism.degradation.starch.starch phosphorylase","PACid:16408656","Glycosyl transferase, family 35",-0.939]
["Oxidative pentose phosphate pathway"]
["7.1.1","OPP.oxidative PP.G6PD","PACid:16429295","glucose-6-phosphate dehydrogenase 2",-2.184]
["TCA cycle/organic acid transformations"]
["8.1.1.1","TCA / org transformation.TCA.pyruvate DH.E1","PACid:16429310","Transketolase family protein",2.039]
[8.3,"TCA / org transformation.carbonic anhydrases","PACid:16424915","beta carbonic anhydrase 4",2.572]
["Cell wall"]
["10.6.1","cell wall.degradation.cellulases and beta -1,4-glucanases","PACid:16404978","Glycosyl hydrolase family protein",-0.75]
["Lipid metabolism"]
["11.1.8","lipid metabolism.FA synthesis and FA elongation.acyl coa ligase","PACid:16405411","acyl-activating enzyme 7",3.405]
["11.1.9","lipid metabolism.FA synthesis and FA elongation.long chain fatty acid CoA ligase","PACid:16408331","AMP-dependent synthetase and ligase family protein",4.125]
[11.6,"lipid metabolism.lipid transfer proteins etc","PACid:16409811","lipid transfer protein 4",6.171]
["11.8.10","lipid metabolism.'exotics' (steroids, squalene etc).phosphatidylcholinesterol O-acyltransferase","PACid:16414897","phospholipid:diacylglycerol acyltransferase",-1.378]
["Amino acid metabolism"]
["13.1.1.3.1","amino acid metabolism.synthesis.central amino acid metabolism.alanine.alanine aminotransferase","PACid:16417715","alanine-2-oxoglutarate aminotransferase 2",1.246]
["13.1.5.1.1","amino acid metabolism.synthesis.serine-glycine-cysteine group.serine.phosphoglycerate dehydrogenase","PACid:16418818","D-3-phosphoglycerate dehydrogenase",-1.652]
["Stress"]
[20.1,"stress.biotic","PACid:16411634","chitinase A",1.73]
[20.1,"stress.biotic","PACid:16411621","basic chitinase",-0.97]
["Nucleotide metabolism"]
[23.2,"nucleotide metabolism.degradation","PACid:16422371","uricase / urate oxidase / nodulin 35, putative",-10]
["Miscellaneous enzyme families"]
[26.2,"misc.UDP glucosyl and glucoronyl transferases","PACid:16407009","UDP-glucosyl transferase 74D1",-1.366]
[26.8,"misc.nitrilases, *nitrile lyases, berberine bridge enzymes, reticuline oxidases, troponine reductases","PACid:16425995","methyl esterase 10",3.17]
[26.13,"misc.acid and other phosphatases","PACid:16427718","HAD superfamily, subfamily IIIB acid phosphatase ",-0.84]
[26.22,"misc.short chain dehydrogenase/reductase (SDR)","PACid:16427781","NAD(P)-binding Rossmann-fold superfamily protein",-1.094]
["RNA"]
["27.3.30","RNA.regulation of transcription.Trihelix, Triple-Helix transcription factor family","PACid:16425236","sequence-specific DNA binding transcription factors",-0.871]
["27.3.67","RNA.regulation of transcription.putative transcription regulator","PACid:16412697","Alba DNA/RNA-binding protein",-1.476]
["Protein"]
["29.1.10","protein.aa activation.methionine-tRNA ligase","PACid:16427157","methionine--tRNA ligase, putative / methionyl-tRNA synthetase, putative / MetRS, putative",-2.163]
["29.2.1.1.1.1.3","protein.synthesis.ribosomal protein.prokaryotic.chloroplast.30S subunit.S3","PACid:16403907","structural constituent of ribosome",-0.645]
["29.2.1.1.1.2.29","protein.synthesis.ribosomal protein.prokaryotic.chloroplast.50S subunit.L29","PACid:16423886","Ribosomal L29 family protein ",-0.612]
["29.2.1.2.1.14","protein.synthesis.ribosomal protein.eukaryotic.40S subunit.S14","PACid:16413598","Ribosomal protein S11 family protein",1.62]
["29.2.3","protein.synthesis.initiation","PACid:16412656","eukaryotic translation initiation factor 2 beta subunit",-3.308]
["29.2.4","protein.synthesis.elongation","PACid:16408599","elongation factor Ts family protein",-0.832]
["29.3.4.2","protein.targeting.secretory pathway.golgi","PACid:16424332","Sec23/Sec24 protein transport family protein",-1.273]
["29.5.11.1","protein.degradation.ubiquitin.ubiquitin","PACid:16406935","ubiquitin family protein",-0.936]
["29.5.11.5","protein.degradation.ubiquitin.ubiquitin protease","PACid:16414081","ubiquitin-specific protease 21",-1.387]
["Signalling"]
[30.3,"signalling.calcium","PACid:16411567","Calcium-binding EF-hand family protein",-0.91]
[30.3,"signalling.calcium","PACid:16425142","sodium/calcium exchanger family protein / calcium-binding EF hand family protein",-0.936]
[30.7,"signalling.14-3-3 proteins","PACid:16418358","general regulatory factor 2",-0.772]
["Cell"]
[31.1,"cell.organisation","PACid:16412334","annexin 8",-1.016]
["Not assigned"]
["35.1.19","not assigned.no ontology.C2 domain-containing protein","PACid:16427270","Calcium-dependent lipid-binding (CaLB domain) plant phosphoribosyltransferase family protein",-10]
["1MapMan Bin Code."]
["2MapMan Bin Name."]
["3Phytozome gene identification number."]
["4Phytozome gene description."]
["5Log2 fold change of protein abundances comparing PMeV+PMeV2-infected vs. control plants."]
["Red - Up-accumulated"]
["Green - Down-accumulated"]

{"sheet":"Supplemental Table S10","index":9,"n_rows":139,"n_cols":5,"rows_kept":139,"merged":[[0,0,0,4],[2,0,2,4],[66,0,66,4],[134,0,134,4],[135,0,135,4],[136,0,136,4],[137,0,137,4],[138,0,138,4]]}
["Supplemental Table S10. Proteins differently modulated in 4 months post germination (30 days post inoculation) PMeV+PMeV2-infected C. papaya leaf."]
["Phytozome/NCBI Accession1","Description2","Confidence score3","Anova (p)4","FC5"]
["Up-accumulated proteins"]
["PACid:16420809","haloacid dehalogenase-like hydrolase family protein",22.7,{"v":0.0170801346244829,"d":"0.017"},{"v":2.9995476457214054,"d":"3.00"}]
["PACid:16427159","sucrose phosphate synthase 3F",175.63,{"v":0.0184519007419021,"d":"0.018"},{"v":2.6753115401396754,"d":"2.68"}]
["PACid:16413107","CAP (Cysteine-rich secretory proteins, Antigen 5, and Pathogenesis-related 1 protein) superfamily protein",44.08,{"v":0.0302624836791332,"d":"0.030"},{"v":2.67152160747337,"d":"2.67"}]
["PACid:16431468","alkenal reductase",113.47,{"v":0.0233910135681732,"d":"0.023"},{"v":1.7282263772372626,"d":"1.73"}]
["PACid:16421050","nitrate reductase 2",49.95,{"v":0.0135139565325051,"d":"0.014"},{"v":1.6714676881084456,"d":"1.67"}]
["PACid:16412313","None",37.08,{"v":0.0141344858178142,"d":"0.014"},{"v":1.6428481683353158,"d":"1.64"}]
["PACid:16419415","Eukaryotic aspartyl protease family protein",89.58,{"v":0.0239908782301971,"d":"0.024"},{"v":1.5106289093826288,"d":"1.51"}]
["PACid:16411922","light harvesting complex photosystem II",226.24,{"v":0.0429182145157294,"d":"0.043"},{"v":1.4843192275685797,"d":"1.48"}]
["PACid:16405950","None",90.05,{"v":0.0272211384144764,"d":"0.027"},{"v":1.4640915843769482,"d":"1.46"}]
["PACid:16421146","Mog1/PsbP/DUF1795-like photosystem II reaction center PsbP family protein",40.7,{"v":0.0139779756179423,"d":"0.014"},{"v":1.3659936027588997,"d":"1.37"}]
["GI:167391793","ATP synthase CF0 A subunit (chloroplast) [Carica papaya]",44.2,{"v":3.28359640918563E-3,"d":"0.003"},{"v":1.3073254377925287,"d":"1.31"}]
["PACid:16416428","30S ribosomal protein, putative",181.02,{"v":0.0120717520732573,"d":"0.012"},{"v":1.2731667810860858,"d":"1.27"}]
["PACid:16409579","chloroplast outer envelope protein 37",43.14,{"v":0.033466609183229,"d":"0.033"},{"v":1.258974561617758,"d":"1.26"}]
["PACid:16430998","photosystem II subunit R",165.42,{"v":0.0412483716815901,"d":"0.041"},{"v":1.2325706914629264,"d":"1.23"}]
["PACid:16418478","Insulinase (Peptidase family M16) family protein",64,{"v":0.00687714937830919,"d":"0.007"},{"v":1.2141041843225042,"d":"1.21"}]
["PACid:16412470","NAD(P)-linked oxidoreductase superfamily protein",389.37,{"v":0.0259530073219151,"d":"0.026"},{"v":1.2036181267687749,"d":"1.20"}]
["PACid:16423768","TCP family transcription factor ",16.26,{"v":0.0219878005647995,"d":"0.022"},{"v":1.1878118392257084,"d":"1.19"}]
["PACid:16425469","Mitochondrial substrate carrier family protein",127.32,{"v":0.00314577803916938,"d":"0.003"},{"v":1.1874479339556072,"d":"1.19"}]
["PACid:16416362","None",36.06,{"v":0.0380853366771817,"d":"0.038"},{"v":1.1798380055183237,"d":"1.18"}]
["GI:167391835","photosystem II protein H (chloroplast) [Carica papaya]",66.82,{"v":0.0129284863369544,"d":"0.013"},{"v":1.153366279672566,"d":"1.15"}]
["PACid:16412285","photosystem I subunit O",62.54,{"v":0.00313142825412804,"d":"0.003"},{"v":1.144297072949833,"d":"1.14"}]
["PACid:16421240","Thioredoxin family protein",83.86,{"v":0.0292088155586374,"d":"0.029"},{"v":1.1396008151660166,"d":"1.14"}]
["PACid:16413470","ubiquitin interaction motif-containing protein",16.45,{"v":0.0184682634293055,"d":"0.018"},{"v":1.1275305380922995,"d":"1.13"}]
["PACid:16415334","thioredoxin M-type 4",183.49,{"v":0.0386676857742791,"d":"0.039"},{"v":1.111137747084112,"d":"1.11"}]
["PACid:16429120","PsbQ-like 1",42.69,{"v":0.0103065921963241,"d":"0.010"},{"v":1.109056645904408,"d":"1.11"}]
["PACid:16422090","NAD-dependent malic enzyme 1",24.09,{"v":0.0479718265167617,"d":"0.048"},{"v":1.102828448311549,"d":"1.10"}]
["PACid:16413741","carbonic anhydrase 1",880.96,{"v":0.0472194156638908,"d":"0.047"},{"v":1.0948334334885326,"d":"1.09"}]
["PACid:16428298","Rhodanese/Cell cycle control phosphatase superfamily protein",134.49,{"v":0.010354641536598,"d":"0.010"},{"v":1.0611647078465276,"d":"1.06"}]
["PACid:16415093","glyceraldehyde-3-phosphate dehydrogenase B subunit",818.14,{"v":0.0332787648228071,"d":"0.033"},{"v":1.0448616726943463,"d":"1.04"}]
["GI:167391811","ATP synthase CF1 epsilon subunit (chloroplast) [Carica papaya]",383.78,{"v":0.0360385600035515,"d":"0.036"},{"v":1.0433037376673668,"d":"1.04"}]
["PACid:16406426","zeta-carotene desaturase",47.94,{"v":0.0346136251395316,"d":"0.035"},{"v":1.0307592634817544,"d":"1.03"}]
["PACid:16425084","glycine decarboxylase P-protein 1",1172.08,{"v":0.0394392834579234,"d":"0.039"},{"v":1.0251683773180806,"d":"1.03"}]
["PACid:16418225","PsbQ-like 2",31.23,{"v":0.0497767168966317,"d":"0.050"},{"v":1.0103397123811495,"d":"1.01"}]
["PACid:16432002","photosystem II protein V (chloroplast) [Carica papaya]",57.98,{"v":0.00504316823185902,"d":"0.005"},{"v":1.0068893959423675,"d":"1.01"}]
["PACid:16426635","photosystem I subunit l",43.58,{"v":0.0360495010181585,"d":"0.036"},{"v":1.003477305923398,"d":"1.00"}]
["PACid:16413139","Leucine-rich repeat (LRR) family protein",18.41,{"v":0.0192396946669239,"d":"0.019"},{"v":0.9973530096291598,"d":"1.00"}]
["PACid:16423944","cyclase associated protein 1",43.57,{"v":0.0243779300900784,"d":"0.024"},{"v":0.9830758245407318,"d":"0.98"}]
["PACid:16410085","glutamine synthetase 2",435.16,{"v":0.0243795558057697,"d":"0.024"},{"v":0.9317689622589235,"d":"0.93"}]
["PACid:16424704","uridylyltransferase-related",172.33,{"v":0.0153229077303284,"d":"0.015"},{"v":0.9235390013665992,"d":"0.92"}]
["PACid:16422798","high cyclic electron flow 1",369.94,{"v":0.0402169249997378,"d":"0.040"},{"v":0.9226305055204531,"d":"0.92"}]
["PACid:16409157","lipoamide dehydrogenase 2",533.46,{"v":0.010854932194013,"d":"0.011"},{"v":0.9187247244928689,"d":"0.92"}]
["PACid:16429027","NADPH-dependent thioredoxin reductase C",76.97,{"v":0.0219146245278778,"d":"0.022"},{"v":0.9122526613005896,"d":"0.91"}]
["PACid:16422277","Duplicated homeodomain-like superfamily protein",15.23,{"v":0.0300182338139593,"d":"0.030"},{"v":0.9030498666514128,"d":"0.90"}]
["PACid:16427275","beta glucosidase 34",251.75,{"v":0.0321048084706597,"d":"0.032"},{"v":0.8981849495848899,"d":"0.90"}]
["PACid:16425317","glyceraldehyde 3-phosphate dehydrogenase A subunit",852.26,{"v":0.0343023576209833,"d":"0.034"},{"v":0.8783885522711874,"d":"0.88"}]
["PACid:16424321","long chain acyl-CoA synthetase 9",162.42,{"v":0.0378375120499678,"d":"0.038"},{"v":0.828498705642075,"d":"0.83"}]
["PACid:16406894","Ribonuclease E inhibitor RraA/Dimethylmenaquinone methyltransferase",27.44,{"v":0.0429579007620333,"d":"0.043"},{"v":0.8190159515774125,"d":"0.82"}]
["PACid:16423870","polyamine oxidase 5",18.44,{"v":0.0262504868621991,"d":"0.026"},{"v":0.7909954704521024,"d":"0.79"}]
["PACid:16404385","rubisco activase",2152.37,{"v":0.0429169058636177,"d":"0.043"},{"v":0.7810211056745548,"d":"0.78"}]
["PACid:16422806","fructokinase-like 1",15.37,{"v":0.0192171031779597,"d":"0.019"},{"v":0.7789510553104949,"d":"0.78"}]
["PACid:16430304","FtsH extracellular protease family",110.17,{"v":0.00414923461512062,"d":"0.004"},{"v":0.7737756708231266,"d":"0.77"}]
["PACid:16428265","None",89.33,{"v":0.0122935355447584,"d":"0.012"},{"v":0.7635841703124803,"d":"0.76"}]
["PACid:16420953","thylakoid lumen 18.3 kDa protein",265.04,{"v":0.0309998587743959,"d":"0.031"},{"v":0.748566594387028,"d":"0.75"}]
["PACid:16413084","pyrophosphorylase 6",283.99,{"v":0.0102814678212463,"d":"0.010"},{"v":0.7313213927814598,"d":"0.73"}]
["PACid:16426854","rubisco activase",2131.37,{"v":0.0380440678924864,"d":"0.038"},{"v":0.713402305340879,"d":"0.71"}]
["PACid:16409145","Pectin lyase-like superfamily protein",14.5,{"v":0.0392533816034689,"d":"0.039"},{"v":0.7016112877892561,"d":"0.70"}]
["PACid:16415075","Oxidoreductase family protein",24.07,{"v":0.043933338045427,"d":"0.044"},{"v":0.7015652451944425,"d":"0.70"}]
["PACid:16428426","glycine decarboxylase complex H",179.38,{"v":0.0135519873834733,"d":"0.014"},{"v":0.6942336944673457,"d":"0.69"}]
["PACid:16405405","Class II aaRS and biotin synthetases superfamily protein",59.12,{"v":0.0374642554101395,"d":"0.037"},{"v":0.6592534683699287,"d":"0.66"}]
["PACid:16412072","Chalcone-flavanone isomerase family protein",129.56,{"v":0.000379522804750065,"d":"0.000"},{"v":0.6524412597811857,"d":"0.65"}]
["PACid:16420610","ribosomal protein L9",81.53,{"v":0.00548496917163599,"d":"0.005"},{"v":0.6503297384207221,"d":"0.65"}]
["PACid:16426826","Cyclophilin-like peptidyl-prolyl cis-trans isomerase family protein",54.19,{"v":0.0231781123484572,"d":"0.023"},{"v":0.6498693087817593,"d":"0.65"}]
["PACid:16424781","villin 2",172.37,{"v":0.04987417519691,"d":"0.050"},{"v":0.6453358749271049,"d":"0.65"}]
["Down-accumulated proteins"]
["PACid:16415919","Subtilase family protein",43.6,{"v":0.00402044858521777,"d":"0.004"},"-∞"]
["PACid:16416866","Reticulon family protein",80.91,{"v":2.72933071166381E-4,"d":"0.000"},"-∞"]
["PACid:16419589","P-loop containing nucleoside triphosphate hydrolases superfamily protein",18.55,{"v":0.018370827022077,"d":"0.018"},"-∞"]
["PACid:16420361","Mitochondrial glycoprotein family protein",22.92,{"v":1.36631723941516E-5,"d":"0.000"},"-∞"]
["PACid:16424925","DC1 domain-containing protein",128.33,{"v":0.0138776548392952,"d":"0.014"},{"v":-3.201830088066833,"d":"-3.20"}]
["PACid:16424926","DC1 domain-containing protein",120.88,{"v":0.00697696884942101,"d":"0.007"},{"v":-2.729272030336605,"d":"-2.73"}]
["PACid:16409537","glycosyl hydrolase 9B13",124.9,{"v":0.024329282017281,"d":"0.024"},{"v":-2.5378242850181767,"d":"-2.54"}]
["PACid:16429609","NOP56-like pre RNA processing ribonucleoprotein",116.83,{"v":0.00670462597831489,"d":"0.007"},{"v":-2.2627541763148122,"d":"-2.26"}]
["PACid:16411185","TCP-1/cpn60 chaperonin family protein",174.62,{"v":0.0413349266549915,"d":"0.041"},{"v":-2.229180706025553,"d":"-2.23"}]
["PACid:16424681","vacuolar membrane ATPase 10",51.23,{"v":0.0170002643823263,"d":"0.017"},{"v":-2.109307918994744,"d":"-2.11"}]
["PACid:16420814","importin alpha isoform 4",106.23,{"v":0.00424983110287325,"d":"0.004"},{"v":-2.102523232971804,"d":"-2.10"}]
["PACid:16411576","eukaryotic translation initiation factor 3E",47.97,{"v":4.84572195645727E-3,"d":"0.005"},{"v":-2.0519006035606484,"d":"-2.05"}]
["PACid:16426387","O-Glycosyl hydrolases family 17 protein",64.88,{"v":0.0371531500954476,"d":"0.037"},{"v":-1.9596401134710875,"d":"-1.96"}]
["PACid:16426831","myristoyl-CoA:protein N-myristoyltransferase",20.45,{"v":0.0339699215270651,"d":"0.034"},{"v":-1.8846781494508693,"d":"-1.88"}]
["PACid:16419512","Eukaryotic aspartyl protease family protein",399.76,{"v":0.000710990905671616,"d":"0.001"},{"v":-1.8714534661901763,"d":"-1.87"}]
["PACid:16421623","acyl-CoA dehydrogenase-related",54.22,{"v":0.017293758910676,"d":"0.017"},{"v":-1.8693854925015885,"d":"-1.87"}]
["PACid:16411484","AMP-dependent synthetase and ligase family protein",179.79,{"v":0.0166217174608283,"d":"0.017"},{"v":-1.8417612665757246,"d":"-1.84"}]
["PACid:16430034","Eukaryotic aspartyl protease family protein",376.91,{"v":0.0273628177737875,"d":"0.027"},{"v":-1.770150613237811,"d":"-1.77"}]
["PACid:16408093","Nucleic acid-binding, OB-fold-like protein",64.92,{"v":0.0310919392538546,"d":"0.031"},{"v":-1.7173759426645812,"d":"-1.72"}]
["PACid:16423878","S-adenosyl-L-methionine-dependent methyltransferases superfamily protein",169.48,{"v":0.0165584772597311,"d":"0.017"},{"v":-1.7046456995190702,"d":"-1.70"}]
["PACid:16426399","UDP-Glycosyltransferase superfamily protein",40.53,{"v":0.0110591172357193,"d":"0.011"},{"v":-1.661020607339451,"d":"-1.66"}]
["PACid:16405998","tubulin beta 8",956.15,{"v":0.0050954184110189,"d":"0.005"},{"v":-1.6199139623859728,"d":"-1.62"}]
["PACid:16416704","beta-6 tubulin",554.88,{"v":0.0404877538409976,"d":"0.040"},{"v":-1.5998939391989533,"d":"-1.60"}]
["PACid:16411299","beta-galactosidase 7",43.28,{"v":0.00935916414581661,"d":"0.009"},{"v":-1.5585966941449867,"d":"-1.56"}]
["PACid:16428151","poly(ADP-ribose) polymerase",14.3,{"v":0.0494204372333332,"d":"0.049"},{"v":-1.5124585196033886,"d":"-1.51"}]
["PACid:16404978","Glycosyl hydrolase family protein",288.12,{"v":0.0198060556004259,"d":"0.020"},{"v":-1.4213866123086254,"d":"-1.42"}]
["PACid:16417516","regulatory particle triple-A ATPase 5A",86.12,{"v":0.0193889547593269,"d":"0.019"},{"v":-1.403830324121268,"d":"-1.40"}]
["PACid:16428909","regulatory particle AAA-ATPase 2A",191.73,{"v":0.0367219460765295,"d":"0.037"},{"v":-1.3560781383980784,"d":"-1.36"}]
["PACid:16422729","ATPase, AAA-type, CDC48 protein",240.43,{"v":0.000287006982416793,"d":"0.000"},{"v":-1.3186701451986982,"d":"-1.32"}]
["PACid:16430932","O-fucosyltransferase family protein",62.33,{"v":0.0414171941936967,"d":"0.041"},{"v":-1.2629040347155474,"d":"-1.26"}]
["PACid:16407727","Transcriptional coactivator/pterin dehydratase",40.13,{"v":0.0410165717747868,"d":"0.041"},{"v":-1.206204286034192,"d":"-1.21"}]
["PACid:16418291","U5 small nuclear ribonucleoprotein helicase, putative",164.7,{"v":0.0362865785750123,"d":"0.036"},{"v":-1.2038295372806798,"d":"-1.20"}]
["PACid:16413069","ribophorin II (RPN2) family protein",65.96,{"v":0.0290165821463315,"d":"0.029"},{"v":-1.1629888780335904,"d":"-1.16"}]
["PACid:16426335","regulatory particle non-ATPase 12A",54.65,{"v":0.0203902055388756,"d":"0.020"},{"v":-1.111142380953217,"d":"-1.11"}]
["PACid:16425490","P-loop containing nucleoside triphosphate hydrolases superfamily protein",69.33,{"v":0.036060667050956,"d":"0.036"},{"v":-1.0894207897432537,"d":"-1.09"}]
["PACid:16416571","ribosomal protein S13A",84.32,{"v":1.43794724738067E-3,"d":"0.001"},{"v":-1.0659546966383224,"d":"-1.07"}]
["PACid:16427467","P-loop containing nucleoside triphosphate hydrolases superfamily protein",205.33,{"v":0.00892092374868958,"d":"0.009"},{"v":-1.0566511392718965,"d":"-1.06"}]
["PACid:16413762","PDI-like 1-4",121.19,{"v":0.0447044601515639,"d":"0.045"},{"v":-1.0386645920649829,"d":"-1.04"}]
["PACid:16420853","ATP-citrate lyase A-3",72.22,{"v":0.0139488695611102,"d":"0.014"},{"v":-1.0369193277384177,"d":"-1.04"}]
["PACid:16416709","Calcium-binding EF-hand family protein",80.77,{"v":0.0291263611201911,"d":"0.029"},{"v":-1.0146710252730708,"d":"-1.01"}]
["PACid:16431432","Microsomal signal peptidase 25 kDa subunit (SPC25)",34.83,{"v":0.0153114013111484,"d":"0.015"},{"v":-0.9790302688643905,"d":"-0.98"}]
["PACid:16409224","pathogenesis-related 4",207.21,{"v":0.0065315550552123,"d":"0.007"},{"v":-0.9494176146233297,"d":"-0.95"}]
["PACid:16413132","Cyclase family protein",34.03,{"v":0.0294692611094257,"d":"0.029"},{"v":-0.9304684284496387,"d":"-0.93"}]
["PACid:16412735","sorting nexin 2A",49.23,{"v":0.0209358673398843,"d":"0.021"},{"v":-0.9185751361343922,"d":"-0.92"}]
["PACid:16421699","rhamnose biosynthesis 1",67.78,{"v":0.0259179190566003,"d":"0.026"},{"v":-0.8405517349336887,"d":"-0.84"}]
["PACid:16428767","heat shock protein 101",77.65,{"v":0.0249698748859676,"d":"0.025"},{"v":-0.7915666667927171,"d":"-0.79"}]
["PACid:16427981","importin alpha isoform 1",70.78,{"v":0.013893415175939,"d":"0.014"},{"v":-0.7626624484695196,"d":"-0.76"}]
["PACid:16431114","Serine protease inhibitor (SERPIN) family protein",65.7,{"v":0.0365708455798276,"d":"0.037"},{"v":-0.7480588664506092,"d":"-0.75"}]
["PACid:16403847","beta-D-xylosidase 4",252.22,{"v":0.0383641288290915,"d":"0.038"},{"v":-0.7433273269858833,"d":"-0.74"}]
["PACid:16413146","poly(A) binding protein 2",139.48,{"v":0.00910569195960642,"d":"0.009"},{"v":-0.7355848772979198,"d":"-0.74"}]
["PACid:16428304","serine carboxypeptidase-like 33",149.42,{"v":0.0396666456789092,"d":"0.040"},{"v":-0.7107523369639068,"d":"-0.71"}]
["PACid:16430896","annexin 8",124.55,{"v":0.0053787949570655,"d":"0.005"},{"v":-0.7042808261822405,"d":"-0.70"}]
["PACid:16423532","catalase 2",1306.22,{"v":0.0211647499282663,"d":"0.021"},{"v":-0.7042147795418505,"d":"-0.70"}]
["PACid:16407440","S-adenosyl-L-methionine-dependent methyltransferases superfamily protein",15.35,{"v":0.0271634188312077,"d":"0.027"},{"v":-0.6945936112578595,"d":"-0.69"}]
["PACid:16428198","pfkB-like carbohydrate kinase family protein",247.48,{"v":0.020488232652474,"d":"0.020"},{"v":-0.6861865354397167,"d":"-0.69"}]
["PACid:16414807","regulatory particle triple-A 1A",90.4,{"v":0.00280211570941402,"d":"0.003"},{"v":-0.6820762302347337,"d":"-0.68"}]
["PACid:16413698","annexin 2",256.94,{"v":0.00202118738488577,"d":"0.002"},{"v":-0.6683161191047594,"d":"-0.67"}]
["PACid:16429726","threonine aldolase 1",43.42,{"v":0.01712118120858,"d":"0.017"},{"v":-0.6540090935851255,"d":"-0.65"}]
["PACid:16408635","U-box domain-containing protein",77.45,{"v":0.048790812134561,"d":"0.049"},{"v":-0.6482633741679756,"d":"-0.65"}]
["PACid:16414081","ubiquitin-specific protease 21",24.89,{"v":0.0433111385032948,"d":"0.043"},{"v":-0.6428586682801414,"d":"-0.64"}]
["PACid:16408020","Ribosomal L28e protein family",33.14,{"v":0.0384518738359292,"d":"0.038"},{"v":-0.6399674953445205,"d":"-0.64"}]
["PACid:16405397","fibrillarin 2",32.67,{"v":0.0238583802125095,"d":"0.024"},{"v":-0.6318591178476488,"d":"-0.63"}]
["PACid:16407705","calnexin 1",281.89,{"v":0.0146110186395195,"d":"0.015"},{"v":-0.620364263253785,"d":"-0.62"}]
["PACid:16411594","GHMP kinase family protein",34.33,{"v":0.0142598929185883,"d":"0.014"},{"v":-0.6185851819906232,"d":"-0.62"}]
["PACid:16418246","U2 snRNP auxilliary factor, large subunit, splicing factor",61.69,{"v":0.0496785922101273,"d":"0.050"},{"v":-0.6148745258014742,"d":"-0.61"}]
["PACid:16432172","O-fucosyltransferase family protein",36.48,{"v":0.00768975275336681,"d":"0.008"},{"v":-0.6113124070550352,"d":"-0.61"}]
["PACid:16406190","acetyl Co-enzyme a carboxylase biotin carboxylase subunit",484.32,{"v":0.0163636055622133,"d":"0.016"},{"v":-0.603766560089748,"d":"-0.60"}]
["1Phytozome or NCBI gene identification number."]
["2Phytozome or NCBI gene description."]
["3Quality assurance scores for protein alignment by Progenesis QI."]
["4Analysis of variance (ANOVA) based p value (p≤0.05)."]
["5Log2 fold change of protein abundances comparing PMeV+PMeV2-infected vs. control plants."]

{"sheet":"Supplemental Table S11","index":10,"n_rows":162,"n_cols":5,"rows_kept":162,"merged":[[2,0,2,4],[18,0,18,4],[22,0,22,4],[24,0,24,4],[29,0,29,4],[36,0,36,4],[41,0,41,4],[44,0,44,4],[47,0,47,4],[51,0,51,4],[53,0,53,4],[59,0,59,4],[64,0,64,4],[67,0,67,4],[69,0,69,4],[77,0,77,4],[88,0,88,4],[92,0,92,4],[120,0,120,4],[124,0,124,4],[131,0,131,4],[134,0,134,4],[155,0,155,4],[156,0,156,4],[157,0,157,4],[158,0,158,4],[159,0,159,4],[160,0,160,4],[161,0,161,4]]}
["Supplemental Table S11. Metabolic pathway overview of abundance changed proteins in 4 months post germination (30 days post inoculation) PMeV+PMeV2-infected and control C. papaya leaf samples."]
["Bin Code1","Bin Name2","Protein ID3","Protein Description4","FC5"]
["Photosynthesis"]
["1.1.1.1","PS.lightreaction.photosystem II.LHC-II","PACid:16411922","light harvesting complex photosystem II",1.484]
["1.1.1.2","PS.lightreaction.photosystem II.PSII polypeptide subunits","PACid:16418225","PsbQ-like 2",1.01]
["1.1.1.2","PS.lightreaction.photosystem II.PSII polypeptide subunits","PACid:16421146","Mog1/PsbP/DUF1795-like photosystem II reaction center PsbP family protein",1.366]
["1.1.1.2","PS.lightreaction.photosystem II.PSII polypeptide subunits","PACid:16429120","PsbQ-like 1",1.109]
["1.1.1.2","PS.lightreaction.photosystem II.PSII polypeptide subunits","PACid:16432002","photosystem II protein V (chloroplast) [Carica papaya]",1.007]
["1.1.1.2","PS.lightreaction.photosystem II.PSII polypeptide subunits","PACid:16430998","photosystem II subunit R",1.233]
["1.1.2.2","PS.lightreaction.photosystem I.PSI polypeptide subunits","PACid:16412285","photosystem I subunit O",1.144]
["1.1.2.2","PS.lightreaction.photosystem I.PSI polypeptide subunits","PACid:16426635","photosystem I subunit l",1.003]
["1.2.4.4","PS.photorespiration.glycine cleavage.H protein","PACid:16428426","glycine decarboxylase complex H",0.694]
["1.3.4","PS.calvin cycle.GAP","PACid:16425317","glyceraldehyde 3-phosphate dehydrogenase A subunit",0.878]
["1.3.4","PS.calvin cycle.GAP","PACid:16415093","glyceraldehyde-3-phosphate dehydrogenase B subunit",1.045]
["1.3.7","PS.calvin cycle.FBPase","PACid:16422798","high cyclic electron flow 1",0.923]
["1.3.13","PS.calvin cycle.rubisco interacting","PACid:16426854","rubisco activase",0.713]
["1.3.13","PS.calvin cycle.rubisco interacting","PACid:16404385","rubisco activase; 26S proteasome regulatory complex, ATPase RPT4",0.781]
["1.3.13","PS.calvin cycle.rubisco interacting","PACid:16425490","P-loop containing nucleoside triphosphate hydrolases superfamily protein",-1.089]
["Major carbohydrates"]
["2.1.1.1","major CHO metabolism.synthesis.sucrose.SPS","PACid:16427159","sucrose phosphate synthase 3F",2.675]
["2.2.1.1","major CHO metabolism.degradation.sucrose.fructokinase","PACid:16428198","pfkB-like carbohydrate kinase family protein",-0.686]
["2.2.1.1","major CHO metabolism.degradation.sucrose.fructokinase","PACid:16422806","fructokinase-like 1",0.779]
["Minor carbohydrates"]
["3.5","minor CHO metabolism.others","PACid:16412470","NAD(P)-linked oxidoreductase superfamily protein",1.204]
["TCA cycle/organic acid transformations"]
["8.1.1.3","TCA / org transformation.TCA.pyruvate DH.E3","PACid:16409157","lipoamide dehydrogenase 2",0.919]
["8.2.10","TCA / org transformation.other organic acid transformatons.malic","PACid:16422090","NAD-dependent malic enzyme 1",1.103]
["8.2.11","TCA / org transformation.other organic acid transformatons.atp-citrate lyase","PACid:16420853","ATP-citrate lyase A-3",-1.037]
["8.3","TCA / org transformation.carbonic anhydrases","PACid:16413741","carbonic anhydrase 1",1.095]
["Cell wall"]
["10.1.10","cell wall.precursor synthesis.UDP-glucose 4,6-dehydratase","PACid:16421699","rhamnose biosynthesis 1",-0.841]
["10.5.3","cell wall.cell wall proteins.LRR","PACid:16413139","Leucine-rich repeat (LRR) family protein",0.997]
["10.6.1","cell wall.degradation.cellulases and beta -1,4-glucanases","PACid:16404978","Glycosyl hydrolase family protein",-1.421]
["10.6.1","cell wall.degradation.cellulases and beta -1,4-glucanases","PACid:16409537","glycosyl hydrolase 9B13",-2.538]
["10.6.2","cell wall.degradation.mannan-xylose-arabinose-fucose","PACid:16403847","beta-D-xylosidase 4",-0.743]
["10.6.3","cell wall.degradation.pectate lyases and polygalacturonases","PACid:16409145","Pectin lyase-like superfamily protein",0.702]
["Lipid metabolism"]
["11.1.1.2.4","lipid metabolism.FA synthesis and FA elongation.Acetyl CoA Carboxylation.heteromeric Complex.Biotin Carboxylase","PACid:16406190","acetyl Co-enzyme a carboxylase biotin carboxylase subunit",-0.604]
["11.1.9","lipid metabolism.FA synthesis and FA elongation.long chain fatty acid CoA ligase","PACid:16411484","AMP-dependent synthetase and ligase family protein",-1.842]
["11.1.9","lipid metabolism.FA synthesis and FA elongation.long chain fatty acid CoA ligase","PACid:16424321","long chain acyl-CoA synthetase 9",0.828]
["11.9.4.2","lipid metabolism.lipid degradation.beta-oxidation.acyl CoA DH","PACid:16421623","acyl-CoA dehydrogenase-related",-1.869]
["Nitrogen metabolism"]
["12.1.1","N-metabolism.nitrate metabolism.NR","PACid:16421050","nitrate reductase 2",1.671]
["12.2.2","N-metabolism.ammonia metabolism.glutamine synthetase","PACid:16410085","glutamine synthetase 2",0.932]
["Amino acid metabolism"]
["13.2.5.2","amino acid metabolism.degradation.serine-glycine-cysteine group.glycine","PACid:16429726","threonine aldolase 1",-0.654]
["13.2.5.2","amino acid metabolism.degradation.serine-glycine-cysteine group.glycine","PACid:16425084","glycine decarboxylase P-protein 1",1.025]
["Secondary metabolism"]
["16.1.2.6","secondary metabolism.isoprenoids.mevalonate pathway.mevalonate diphosphate decarboxylase","PACid:16411594","GHMP kinase family protein",-0.619]
["16.1.4.3","secondary metabolism.isoprenoids.carotenoids.zeta-carotene desaturase","PACid:16406426","zeta-carotene desaturase",1.031]
["16.8.2","secondary metabolism.flavonoids.chalcones","PACid:16412072","Chalcone-flavanone isomerase family protein",0.652]
["Hormone metabolism"]
["17.2.3","hormone metabolism.auxin.induced-regulated-responsive-activated","PACid:16430932","O-fucosyltransferase family protein",-1.263]
["Stress"]
["20.1","stress.biotic","PACid:16413107","CAP (Cysteine-rich secretory proteins, Antigen 5, and Pathogenesis-related 1 protein) superfamily protein",2.672]
["20.1","stress.biotic","PACid:16409224","pathogenesis-related 4",-0.949]
["20.2.1","stress.abiotic.heat","PACid:16428767","heat shock protein 101",-0.792]
["20.2.3","stress.abiotic.drought/salt","PACid:16407440","S-adenosyl-L-methionine-dependent methyltransferases superfamily protein",-0.695]
["20.2.3","stress.abiotic.drought/salt","PACid:16423878","S-adenosyl-L-methionine-dependent methyltransferases superfamily protein",-1.705]
["Redox"]
["21.1","redox.thioredoxin","PACid:16415334","thioredoxin M-type 4",1.111]
["21.1","redox.thioredoxin","PACid:16429027","NADPH-dependent thioredoxin reductase C",0.912]
["21.1.1","redox.thioredoxin.PDIL","PACid:16413762","PDI-like 1-4",-1.039]
["21.6","redox.dismutases and catalases","PACid:16423532","catalase 2",-0.704]
["Nucleotide metabolism"]
["23.4.3","nucleotide metabolism.phosphotransfer and pyrophosphatases.uridylate kinase","PACid:16419589","P-loop containing nucleoside triphosphate hydrolases superfamily protein",-10]
["23.4.99","nucleotide metabolism.phosphotransfer and pyrophosphatases.misc","PACid:16413084","pyrophosphorylase 6",0.731]
["C1 metabolism"]
["25","C1-metabolism","PACid:16406894","Ribonuclease E inhibitor RraA/Dimethylmenaquinone methyltransferase",0.819]
["Miscellaneous enzyme families"]
["26.2","misc.UDP glucosyl and glucoronyl transferases","PACid:16426399","UDP-Glycosyltransferase superfamily protein",-1.661]
["26.3","misc.gluco-, galacto- and mannosidases","PACid:16427275","beta glucosidase 34",0.898]
["26.3.2","misc.gluco-, galacto- and mannosidases.beta-galactosidase","PACid:16411299","beta-galactosidase 7",-1.559]
["26.3.4","misc.gluco-, galacto- and mannosidases.endoglucanase","PACid:16409537","glycosyl hydrolase 9B13",-2.538]
["26.4.1","misc.beta 1,3 glucan hydrolases.glucan endo-1,3-beta-glucosidase","PACid:16426387","O-Glycosyl hydrolases family 17 protein",-1.96]
["26.7","misc.oxidases - copper, flavone etc","PACid:16431468","alkenal reductase",1.728]
["26.7","misc.oxidases - copper, flavone etc","PACid:16423870","polyamine oxidase 5",0.791]
["RNA"]
["27.1","RNA.processing","PACid:16405397","fibrillarin 2",-0.632]
["27.1","RNA.processing","PACid:16413146","poly(A) binding protein 2",-0.736]
["27.1.1","RNA.processing.splicing","PACid:16418246","U2 snRNP auxilliary factor, large subunit, splicing factor",-0.615]
["27.1.2","RNA.processing.RNA helicase","PACid:16427467","P-loop containing nucleoside triphosphate hydrolases superfamily protein",-1.057]
["27.3.25","RNA.regulation of transcription.MYB domain transcription factor family","PACid:16422277","Duplicated homeodomain-like superfamily protein",0.903]
["27.3.29","RNA.regulation of transcription.TCP transcription factor family","PACid:16423768","TCP family transcription factor ",1.188]
["27.3.67","RNA.regulation of transcription.putative transcription regulator","PACid:16429609","NOP56-like pre RNA processing ribonucleoprotein",-2.263]
["27.3.99","RNA.regulation of transcription.unclassified","PACid:16419512","Eukaryotic aspartyl protease family protein",-1.871]
["27.3.99","RNA.regulation of transcription.unclassified","PACid:16419415","Eukaryotic aspartyl protease family protein",1.511]
["27.3.99","RNA.regulation of transcription.unclassified","PACid:16430034","Eukaryotic aspartyl protease family protein",-1.77]
["DNA"]
["28.1","DNA.synthesis/chromatin structure","PACid:16418291","U5 small nuclear ribonucleoprotein helicase, putative",-1.204]
["28.99","DNA.unspecified","PACid:16423944","cyclase associated protein 1",0.983]
["28.99","DNA.unspecified","PACid:16413132","Cyclase family protein",-0.93]
["Protein"]
["29.1.40","protein.aa activation.bifunctional aminoacyl-tRNA synthetase","PACid:16405405","Class II aaRS and biotin synthetases superfamily protein",0.659]
["29.2.1.1.1.1.530","protein.synthesis.ribosomal protein.prokaryotic.chloroplast.30S subunit.S30A","PACid:16416428","30S ribosomal protein, putative",1.273]
["29.2.1.1.1.2.9","protein.synthesis.ribosomal protein.prokaryotic.chloroplast.50S subunit.L9","PACid:16420610","ribosomal protein L9",0.65]
["29.2.1.2.1.13","protein.synthesis.ribosomal protein.eukaryotic.40S subunit.S13","PACid:16416571","ribosomal protein S13A",-1.066]
["29.2.1.2.2.28","protein.synthesis.ribosomal protein.eukaryotic.60S subunit.L28","PACid:16408020","Ribosomal L28e protein family",-0.64]
["29.2.2.3.3","protein.synthesis.ribosome biogenesis.Pre-rRNA processing and modifications.methylotransferases","PACid:16405397","fibrillarin 2",-0.632]
["29.2.3","protein.synthesis.initiation","PACid:16411576","eukaryotic translation initiation factor 3E",-2.052]
["29.3.1","protein.targeting.nucleus","PACid:16427981","importin alpha isoform 1",-0.763]
["29.3.1","protein.targeting.nucleus","PACid:16420814","importin alpha isoform 4",-2.103]
["29.3.4.1","protein.targeting.secretory pathway.ER","PACid:16431432","Microsomal signal peptidase 25 kDa subunit (SPC25)",-0.979]
["29.4","protein.postranslational modification","PACid:16428151","poly(ADP-ribose) polymerase",-1.512]
["29.4","protein.postranslational modification","PACid:16426831","myristoyl-CoA:protein N-myristoyltransferase",-1.885]
["29.5","protein.degradation","PACid:16418478","Insulinase (Peptidase family M16) family protein",1.214]
["29.5.1","protein.degradation.subtilases","PACid:16415919","Subtilase family protein/ SUBTILISIN SERINE PROTEASE-RELATED",-10]
["29.5.5","protein.degradation.serine protease","PACid:16428304","serine carboxypeptidase-like 33",-0.711]
["29.5.5","protein.degradation.serine protease","PACid:16431114","Serine protease inhibitor (SERPIN) family protein",-0.748]
["29.5.7","protein.degradation.metalloprotease","PACid:16430304","FtsH extracellular protease family / METALLOPROTEASE M41 FTSH ",0.774]
["29.5.9","protein.degradation.AAA type","PACid:16422729","ATPase, AAA-type, CDC48 protein / Vesicle-fusing ATPase",-1.319]
["29.5.11","protein.degradation.ubiquitin","PACid:16413470","ubiquitin interaction motif-containing protein",1.128]
["29.5.11","protein.degradation.ubiquitin","PACid:16408635","U-box domain-containing protein / ubiquitin conjugation factor E4 B (UBE4B, UFD2)",-0.648]
["29.5.11.5","protein.degradation.ubiquitin.ubiquitin protease","PACid:16414081","ubiquitin-specific protease 21 / ubiquitin carboxyl-terminal hydrolase 36/42 [EC:3.4.19.12] (USP36_42)/ DUB: deubiquitinating enzyme",-0.643]
["29.5.11.20","protein.degradation.ubiquitin.proteasom","PACid:16417516","regulatory particle triple-A ATPase 5A / 26S proteasome regulatory subunit T5 (PSMC3, RPT5)",-1.404]
["29.5.11.20","protein.degradation.ubiquitin.proteasom","PACid:16426335","regulatory particle non-ATPase 12A / 26S proteasome regulatory subunit N12 (PSMD8, RPN12)",-1.111]
["29.5.11.20","protein.degradation.ubiquitin.proteasom","PACid:16422729","ATPase, AAA-type, CDC48 protein / Vesicle-fusing ATPase",-1.319]
["29.5.11.20","protein.degradation.ubiquitin.proteasom","PACid:16414807","regulatory particle triple-A 1A / 26S proteasome regulatory subunit T1 (PSMC2, RPT1)",-0.682]
["29.5.11.20","protein.degradation.ubiquitin.proteasom","PACid:16428909","regulatory particle AAA-ATPase 2A / 26S proteasome regulatory subunit T2 (PSMC1, RPT2)",-1.356]
["29.6","protein.folding","PACid:16411185","TCP-1/cpn60 chaperonin family protein / T-complex protein 1 subunit zeta (CCT6)",-2.229]
["Signalling"]
["30.2.11","signalling.receptor kinases.leucine rich repeat XI","PACid:16413139","Leucine-rich repeat (LRR) family protein",0.997]
["30.3","signalling.calcium","PACid:16416709","Calcium-binding EF-hand family protein",-1.015]
["30.3","signalling.calcium","PACid:16407705","calnexin 1",-0.62]
["Cell"]
["31.1","cell.organisation","PACid:16416704","beta-6 tubulin",-1.6]
["31.1","cell.organisation","PACid:16424781","villin 2",0.645]
["31.1","cell.organisation","PACid:16413698","annexin 2",-0.668]
["31.1","cell.organisation","PACid:16405998","tubulin beta 8",-1.62]
["31.1","cell.organisation","PACid:16430896","annexin 8",-0.704]
["31.3.1","cell.cycle.peptidylprolyl isomerase","PACid:16426826","Cyclophilin-like peptidyl-prolyl cis-trans isomerase family protein",0.65]
["Transport"]
["34.1","transport.p- and v-ATPases","PACid:16424681","vacuolar membrane ATPase 10",-2.109]
["34.9","transport.metabolite transporters at the mitochondrial membrane","PACid:16425469","Mitochondrial substrate carrier family protein",1.187]
["Not assigned"]
["35.1","not assigned.no ontology","PACid:16420361","Mitochondrial glycoprotein family protein",-10]
["35.1","not assigned.no ontology","PACid:16407727","Transcriptional coactivator/pterin dehydratase",-1.206]
["35.1","not assigned.no ontology","PACid:16416866","Reticulon family protein",-10]
["35.1","not assigned.no ontology","PACid:16415075","Oxidoreductase family protein",0.702]
["35.1","not assigned.no ontology","PACid:16420809","haloacid dehalogenase-like hydrolase family protein",3]
["35.1","not assigned.no ontology","PACid:16412735","sorting nexin 2A",-0.919]
["35.1","not assigned.no ontology","PACid:16420953","thylakoid lumen 18.3 kDa protein",0.749]
["35.1","not assigned.no ontology","PACid:16408093","Nucleic acid-binding, OB-fold-like protein",-1.717]
["35.1","not assigned.no ontology","PACid:16424704","uridylyltransferase-related",0.924]
["35.1.26","not assigned.no ontology.DC1 domain containing protein","PACid:16424926","DC1 domain-containing protein",-2.729]
["35.1.26","not assigned.no ontology.DC1 domain containing protein","PACid:16424925","DC1 domain-containing protein",-3.202]
["35.2","not assigned.unknown","PACid:16428265","None",0.764]
["35.2","not assigned.unknown","PACid:16428298","Rhodanese/Cell cycle control phosphatase superfamily protein",1.061]
["35.2","not assigned.unknown","PACid:16421240","Thioredoxin family protein",1.14]
["35.2","not assigned.unknown","PACid:16412313","None",1.643]
["35.2","not assigned.unknown","PACid:16405950","None",1.464]
["35.2","not assigned.unknown","PACid:16409579","chloroplast outer envelope protein 37",1.259]
["35.2","not assigned.unknown","PACid:16416362","None",1.18]
["35.2","not assigned.unknown","PACid:16413069","ribophorin II (RPN2) family protein",-1.163]
["35.2","not assigned.unknown","PACid:16432172","O-fucosyltransferase family protein",-0.611]
["1MapMan Bin Code."]
["2MapMan Bin Name."]
["3Phytozome gene identification number."]
["4Phytozome gene description."]
["5Log2 fold change of protein abundances comparing PMeV+PMeV2-infected vs. control plants."]
["Red - Up-accumulated"]
["Green - Down-accumulated"]

{"sheet":"Supplemental Table S12","index":11,"n_rows":169,"n_cols":5,"rows_kept":169,"merged":[[0,0,0,4],[2,0,2,4],[152,0,152,4],[164,0,164,4],[165,0,165,4],[166,0,166,4],[167,0,167,4],[168,0,168,4]]}
["Supplemental Table S12. Proteins differently modulated in 7 months post germination (120 days post inoculation) PMeV+PMeV2-infected C. papaya leaf."]
["Phytozome/NCBI Accession1","Description2","Confidence score3","Anova (p)4","FC5"]
["Up-accumulated proteins"]
["PACid:16425167","alpha/beta-Hydrolases superfamily protein",70.84,{"v":0.00479544298277568,"d":"0.005"},{"v":4.1811976440280425,"d":"4.18"}]
["PACid:16414854","DEA(D/H)-box RNA helicase family protein",78.53,{"v":0.0116426844019927,"d":"0.012"},{"v":3.126027960769762,"d":"3.13"}]
["PACid:16420664","Adaptor protein complex AP-2, alpha subunit",43.87,{"v":0.0180117691662962,"d":"0.018"},{"v":2.8672493175424676,"d":"2.87"}]
["PACid:16426114","None",20.1,{"v":0.0345015963515423,"d":"0.035"},{"v":2.51767346252353,"d":"2.52"}]
["PACid:16425995","methyl esterase 10",13.16,{"v":0.030720334816781,"d":"0.031"},{"v":2.3691837421623165,"d":"2.37"}]
["PACid:16429356","Mov34/MPN/PAD-1 family protein",187.68,{"v":0.0146754033992043,"d":"0.015"},{"v":2.241240932866064,"d":"2.24"}]
["PACid:16410436","root FNR 1",37.56,{"v":0.0417177481451635,"d":"0.042"},{"v":2.2282731360316066,"d":"2.23"}]
["PACid:16418327","general regulatory factor 11",206.53,{"v":0.038561139078655,"d":"0.039"},{"v":2.2269594013197205,"d":"2.23"}]
["PACid:16411641","MAP kinase 4",43.78,{"v":0.0227871460519018,"d":"0.023"},{"v":2.137766397236987,"d":"2.14"}]
["PACid:16429196","ureidoglycine aminohydrolase",43.92,{"v":1.85137222671083E-3,"d":"0.002"},{"v":2.054200370252818,"d":"2.05"}]
["PACid:16412227","60S acidic ribosomal protein family",180.19,{"v":0.00732673169096121,"d":"0.007"},{"v":1.9214939983045218,"d":"1.92"}]
["PACid:16426518","UDP-glucosyl transferase 71B1",17.94,{"v":0.0147881760721933,"d":"0.015"},{"v":1.879543528120584,"d":"1.88"}]
["PACid:16428415","ARF-GAP domain 8",49.31,{"v":0.0234454937571174,"d":"0.023"},{"v":1.8773933765949338,"d":"1.88"}]
["PACid:16420360","Glucose-1-phosphate adenylyltransferase family protein",22.02,{"v":0.0145548871400449,"d":"0.015"},{"v":1.867036667505228,"d":"1.87"}]
["PACid:16425098","gamma vacuolar processing enzyme",19.3,{"v":0.000267779830412929,"d":"0.000"},{"v":1.8561706348315121,"d":"1.86"}]
["PACid:16425960","mitochondrial HSO70 2",156.04,{"v":0.0228906865664584,"d":"0.023"},{"v":1.8386777073357117,"d":"1.84"}]
["PACid:16426929","SWAP (Suppressor-of-White-APricot)/surp RNA-binding domain-containing protein",19.5,{"v":0.0248883723362323,"d":"0.025"},{"v":1.8121796846042708,"d":"1.81"}]
["PACid:16412697","Alba DNA/RNA-binding protein",56.52,{"v":0.0372567999879837,"d":"0.037"},{"v":1.7913947499575522,"d":"1.79"}]
["PACid:16416617","mitochondrion-localized small heat shock protein 23.6",60.7,{"v":0.00751939462816587,"d":"0.008"},{"v":1.7454425818144508,"d":"1.75"}]
["PACid:16411051","Tetratricopeptide repeat (TPR)-like superfamily protein",130.26,{"v":0.0265717015345525,"d":"0.027"},{"v":1.7080515921984432,"d":"1.71"}]
["PACid:16423953","phenylalanyl-tRNA synthetase, putative / phenylalanine--tRNA ligase, putative",81.46,{"v":0.0106223027233003,"d":"0.011"},{"v":1.7007699834873016,"d":"1.70"}]
["PACid:16427150","None",378.99,{"v":0.032358959431309,"d":"0.032"},{"v":1.6485189104479587,"d":"1.65"}]
["PACid:16423462","proteasome alpha subunit D2",169.49,{"v":0.0375542949866436,"d":"0.038"},{"v":1.5986639974797239,"d":"1.60"}]
["PACid:16423092","D-isomer specific 2-hydroxyacid dehydrogenase family protein",55.58,{"v":0.0165124365804213,"d":"0.017"},{"v":1.5892840132268364,"d":"1.59"}]
["PACid:16416992","serine hydroxymethyltransferase 3",48.69,{"v":0.0413371003731398,"d":"0.041"},{"v":1.5851729940484112,"d":"1.59"}]
["PACid:16416747","transducin family protein / WD-40 repeat family protein",38.13,{"v":0.0147031531464928,"d":"0.015"},{"v":1.5840650112358141,"d":"1.58"}]
["PACid:16428853","subtilisin-like serine protease 3",22.31,{"v":0.0372495256380591,"d":"0.037"},{"v":1.5797372133340053,"d":"1.58"}]
["PACid:16416771","HSP20-like chaperones superfamily protein",27.8,{"v":0.0107468912812687,"d":"0.011"},{"v":1.5627439762567958,"d":"1.56"}]
["PACid:16420148","Pyruvate kinase family protein",28.15,{"v":0.0209137280836262,"d":"0.021"},{"v":1.5466531239142405,"d":"1.55"}]
["PACid:16422738","uracil phosphoribosyltransferase",47.85,{"v":0.0442520311407758,"d":"0.044"},{"v":1.5255980514796925,"d":"1.53"}]
["PACid:16421573","glutathione S-transferase PHI 9",486.36,{"v":0.0380883158761118,"d":"0.038"},{"v":1.4789485788931407,"d":"1.48"}]
["PACid:16410427","urease accessory protein G",201.03,{"v":0.0187924737729175,"d":"0.019"},{"v":1.441570531388251,"d":"1.44"}]
["PACid:16429423","pentatricopeptide (PPR) repeat-containing protein",13.75,{"v":0.0476988082008452,"d":"0.048"},{"v":1.4355590342078564,"d":"1.44"}]
["PACid:16409579","chloroplast outer envelope protein 37",43.14,{"v":0.0477397207496775,"d":"0.048"},{"v":1.368762521652158,"d":"1.37"}]
["PACid:16425809","Nuclear transport factor 2 (NTF2) family protein with RNA binding (RRM-RBD-RNP motifs) domain",43.24,{"v":0.0173863511368476,"d":"0.017"},{"v":1.3526082714407925,"d":"1.35"}]
["GI:167391831","ATP-dependent Clp protease proteolytic subunit (chloroplast) [Carica papaya]",226.37,{"v":0.00273730014945173,"d":"0.003"},{"v":1.3491549674368266,"d":"1.35"}]
["PACid:16421838","GDSL-like Lipase/Acylhydrolase superfamily protein",243.83,{"v":0.00359349592917368,"d":"0.004"},{"v":1.3315560069613777,"d":"1.33"}]
["PACid:16410318","RP non-ATPase subunit 8A",87.78,{"v":0.00833346470115659,"d":"0.008"},{"v":1.3250694763779864,"d":"1.33"}]
["PACid:16425955","Leucine-rich repeat protein kinase family protein",15.13,{"v":4.94379077900731E-3,"d":"0.005"},{"v":1.3031998987402613,"d":"1.30"}]
["PACid:16429335","TCP-1/cpn60 chaperonin family protein",338.47,{"v":0.00909258671557955,"d":"0.009"},{"v":1.2966784212622187,"d":"1.30"}]
["PACid:16407544","peroxisomal NAD-malate dehydrogenase 1",311.43,{"v":0.0116900954315838,"d":"0.012"},{"v":1.2768523010642863,"d":"1.28"}]
["PACid:16412645","regulatory particle triple-A ATPase 3",90.74,{"v":0.0149135782114669,"d":"0.015"},{"v":1.2750128855364822,"d":"1.28"}]
["PACid:16428030","gamma histone variant H2AX",68.53,{"v":0.0422443253264249,"d":"0.042"},{"v":1.2718300919771632,"d":"1.27"}]
["PACid:16411947","Ribosomal protein L10 family protein",303.53,{"v":0.00928832359630172,"d":"0.009"},{"v":1.2611960230364234,"d":"1.26"}]
["PACid:16413034","aspartate aminotransferase",43.12,{"v":0.0162082219830264,"d":"0.016"},{"v":1.2195118228771227,"d":"1.22"}]
["PACid:16415916","NagB/RpiA/CoA transferase-like superfamily protein",168.97,{"v":0.0121482257566808,"d":"0.012"},{"v":1.2042330098202008,"d":"1.20"}]
["PACid:16416453","SPFH/Band 7/PHB domain-containing membrane-associated protein family",74.17,{"v":0.0136585028430759,"d":"0.014"},{"v":1.1978527288592147,"d":"1.20"}]
["PACid:16428003","GTP binding Elongation factor Tu family protein",167.67,{"v":0.0269123337125876,"d":"0.027"},{"v":1.1964965315546203,"d":"1.20"}]
["PACid:16420362","delta 1-pyrroline-5-carboxylate synthase 2",43.99,{"v":0.0141894526898741,"d":"0.014"},{"v":1.1917725150498226,"d":"1.19"}]
["PACid:16407265","None",56.26,{"v":0.0487485476932319,"d":"0.049"},{"v":1.1819331588099535,"d":"1.18"}]
["PACid:16427279","gamma histone variant H2AX",113.2,{"v":0.0374892965140874,"d":"0.037"},{"v":1.1787061047747303,"d":"1.18"}]
["PACid:16412130","histone H2A 12",324.16,{"v":0.0296823952677001,"d":"0.030"},{"v":1.169319680114067,"d":"1.17"}]
["PACid:16408534","histidinol dehydrogenase",110.54,{"v":0.0221141061875885,"d":"0.022"},{"v":1.1629191984850913,"d":"1.16"}]
["PACid:16404356","triosephosphate isomerase",587.62,{"v":0.034745968781757,"d":"0.035"},{"v":1.161779111156468,"d":"1.16"}]
["PACid:16403829","Succinyl-CoA ligase, alpha subunit",48.28,{"v":0.0263962098136084,"d":"0.026"},{"v":1.1605604487640375,"d":"1.16"}]
["PACid:16418455","Sugar isomerase (SIS) family protein",118.53,{"v":0.0191287040151814,"d":"0.019"},{"v":1.1536944082504133,"d":"1.15"}]
["PACid:16427501","actin-11",555.43,{"v":0.0118720078696367,"d":"0.012"},{"v":1.1532211980714349,"d":"1.15"}]
["PACid:16413596","KH domain-containing protein",23.68,{"v":0.0461410558889997,"d":"0.046"},{"v":1.1494966416417192,"d":"1.15"}]
["PACid:16418661","methylthioadenosine nucleosidase 1",43.42,{"v":0.0264743102907887,"d":"0.026"},{"v":1.1484914068355685,"d":"1.15"}]
["PACid:16426375","glyoxylate reductase 1",206.04,{"v":0.0212522109609767,"d":"0.021"},{"v":1.1441114272981165,"d":"1.14"}]
["PACid:16422232","binding to TOMV RNA 1L (long form)",31.85,{"v":0.0333511388375511,"d":"0.033"},{"v":1.134883285900279,"d":"1.13"}]
["PACid:16415072","Photosystem II reaction center PsbP family protein",91.78,{"v":0.0189932009481327,"d":"0.019"},{"v":1.1319794060091486,"d":"1.13"}]
["PACid:16427467","P-loop containing nucleoside triphosphate hydrolases superfamily protein",205.33,{"v":0.0346009477646299,"d":"0.035"},{"v":1.1233835034235666,"d":"1.12"}]
["PACid:16428900","voltage dependent anion channel 4",125.12,{"v":0.0138103382447942,"d":"0.014"},{"v":1.089614077423235,"d":"1.09"}]
["PACid:16416231","nucleotide-rhamnose synthase/epimerase-reductase",96.38,{"v":0.00440241362852123,"d":"0.004"},{"v":1.0757026999485606,"d":"1.08"}]
["PACid:16414029","uridine 5\\'-monophosphate synthase / UMP synthase (PYRE-F) (UMPS)",20.29,{"v":0.00614635458209933,"d":"0.006"},{"v":1.0672829715186727,"d":"1.07"}]
["PACid:16427399","Enoyl-CoA hydratase/isomerase family",39.94,{"v":0.044068209693258,"d":"0.044"},{"v":1.0655575654728011,"d":"1.07"}]
["PACid:16416361","glutamine synthase clone R1",203.95,{"v":0.0310708143379231,"d":"0.031"},{"v":1.043130088392631,"d":"1.04"}]
["PACid:16419957","Nucleotide-diphospho-sugar transferases superfamily protein",42.75,{"v":0.0406689706255393,"d":"0.041"},{"v":1.0291252713166834,"d":"1.03"}]
["PACid:16417615","NAD(P)-linked oxidoreductase superfamily protein",178.46,{"v":1.70563696277726E-3,"d":"0.002"},{"v":1.0255958328491852,"d":"1.03"}]
["PACid:16423410","NAD(P)-binding Rossmann-fold superfamily protein",37.01,{"v":0.00165934148197211,"d":"0.002"},{"v":1.025082415758624,"d":"1.03"}]
["PACid:16411964","L-Aspartase-like family protein",42.78,{"v":0.0200685785497513,"d":"0.020"},{"v":1.0242782913817758,"d":"1.02"}]
["PACid:16406784","homolog of bacterial cytokinesis Z-ring protein FTSZ 1-1",205.63,{"v":0.0424049372956069,"d":"0.042"},{"v":1.0238927376826588,"d":"1.02"}]
["PACid:16414159","aldehyde dehydrogenase 2C4",67.66,{"v":0.0260107442143106,"d":"0.026"},{"v":1.0094661393118531,"d":"1.01"}]
["PACid:16421709","Phosphoribosyltransferase family protein",44.2,{"v":0.0335501837408491,"d":"0.034"},{"v":1.0032242511063838,"d":"1.00"}]
["PACid:16409578","None",41.55,{"v":0.0462652758276275,"d":"0.046"},{"v":0.9952721080832451,"d":"1.00"}]
["PACid:16415012","Disease resistance-responsive (dirigent-like protein) family protein",41.67,{"v":0.025680259859137,"d":"0.026"},{"v":0.9899852364883205,"d":"0.99"}]
["PACid:16431407","thioredoxin-dependent peroxidase 1",182.21,{"v":0.0225249923735823,"d":"0.023"},{"v":0.9893374803470092,"d":"0.99"}]
["PACid:16416408","NagB/RpiA/CoA transferase-like superfamily protein",68.8,{"v":0.0332263466114838,"d":"0.033"},{"v":0.9762127695418561,"d":"0.98"}]
["PACid:16405261","GroES-like zinc-binding alcohol dehydrogenase family protein",98.52,{"v":0.0400546990380394,"d":"0.040"},{"v":0.9629225918880034,"d":"0.96"}]
["PACid:16422901","pyrophosphorylase 1",103.82,{"v":0.003046463551443,"d":"0.003"},{"v":0.9491265635072632,"d":"0.95"}]
["PACid:16412903","ATPase, V1 complex, subunit B protein",617.88,{"v":2.15032678918503E-3,"d":"0.002"},{"v":0.9480649644742446,"d":"0.95"}]
["PACid:16425533","cinnamyl alcohol dehydrogenase 9",72.32,{"v":0.00233788554715775,"d":"0.002"},{"v":0.9454242229812004,"d":"0.95"}]
["PACid:16423409","voltage dependent anion channel 2",85.1,{"v":0.0170195979925482,"d":"0.017"},{"v":0.9445041768045968,"d":"0.94"}]
["PACid:16407928","prohibitin 3",149.49,{"v":0.0442634029350232,"d":"0.044"},{"v":0.9200602184714369,"d":"0.92"}]
["PACid:16416152","Aldolase superfamily protein",81.89,{"v":0.0397200832118318,"d":"0.040"},{"v":0.9129169936092252,"d":"0.91"}]
["PACid:16412620","None",114.86,{"v":0.0453909545869139,"d":"0.045"},{"v":0.9048605378174236,"d":"0.90"}]
["PACid:16424190","proteasome beta subunit C1",196.55,{"v":0.0414856677015709,"d":"0.041"},{"v":0.9038833179804672,"d":"0.90"}]
["PACid:16416071","Coatomer epsilon subunit",156.65,{"v":0.01655408265092,"d":"0.017"},{"v":0.8994456029919571,"d":"0.90"}]
["PACid:16425372","vacuolar ATP synthase subunit C (VATC) / V-ATPase C subunit / vacuolar proton pump C subunit (DET3)",174.93,{"v":0.045871013947509,"d":"0.046"},{"v":0.8953742775157969,"d":"0.90"}]
["PACid:16425539","Splicing factor, CC1-like",79.67,{"v":0.0354254254582302,"d":"0.035"},{"v":0.8903193574942067,"d":"0.89"}]
["PACid:16427103","sucrose synthase 4",1393.58,{"v":0.0264570076658979,"d":"0.026"},{"v":0.8616317362279453,"d":"0.86"}]
["PACid:16410071","alpha/beta-Hydrolases superfamily protein",296.24,{"v":0.011941419520501,"d":"0.012"},{"v":0.8608938496543755,"d":"0.86"}]
["PACid:16416941","clathrin adaptor complexes medium subunit family protein",176.42,{"v":0.0198424350347275,"d":"0.020"},{"v":0.8591979433167912,"d":"0.86"}]
["PACid:16410388","RNA-binding (RRM/RBD/RNP motifs) family protein",43.17,{"v":0.0460366174078035,"d":"0.046"},{"v":0.8591393223794829,"d":"0.86"}]
["PACid:16429310","Transketolase family protein",40.95,{"v":0.0171504386103227,"d":"0.017"},{"v":0.8526685970218915,"d":"0.85"}]
["PACid:16406589","purin-rich alpha 1",27.95,{"v":0.0169581440544034,"d":"0.017"},{"v":0.8479155785511078,"d":"0.85"}]
["PACid:16418604","proteasome alpha subunit D2",124.17,{"v":0.0253159832295926,"d":"0.025"},{"v":0.8449030644925176,"d":"0.84"}]
["PACid:16404068","ATPase E1",43.25,{"v":0.0133953043288858,"d":"0.013"},{"v":0.8435560569973731,"d":"0.84"}]
["PACid:16427505","Plastid-lipid associated protein PAP / fibrillin family protein",32.1,{"v":0.028920545781313,"d":"0.029"},{"v":0.840073455548856,"d":"0.84"}]
["PACid:16423500","aconitase 1",386.92,{"v":0.0298496980841293,"d":"0.030"},{"v":0.8371037633543881,"d":"0.84"}]
["PACid:16413063","mitochondrial HSO70 2",286.75,{"v":0.00157022814763463,"d":"0.002"},{"v":0.8239628957182749,"d":"0.82"}]
["PACid:16425886","Alba DNA/RNA-binding protein",210.89,{"v":0.0329848009476795,"d":"0.033"},{"v":0.8212885831220499,"d":"0.82"}]
["PACid:16416137","tetraticopeptide domain-containing thioredoxin",220.99,{"v":0.0448898490792883,"d":"0.045"},{"v":0.8212654458994862,"d":"0.82"}]
["PACid:16417130","general regulatory factor 8",210.02,{"v":0.00484888064303046,"d":"0.005"},{"v":0.8176952317901203,"d":"0.82"}]
["GI:224020956","ATP synthase F1 subunit 1 (mitochondrion) [Carica papaya]",379.58,{"v":0.022070269875222,"d":"0.022"},{"v":0.8150185180349698,"d":"0.82"}]
["PACid:16416032","Ribosomal protein S7e family protein",133.88,{"v":0.0276578037892644,"d":"0.028"},{"v":0.8105693752630923,"d":"0.81"}]
["PACid:16405150","AAA-type ATPase family protein",191.65,{"v":0.0471772039556584,"d":"0.047"},{"v":0.80223249214073,"d":"0.80"}]
["PACid:16421200","Pyruvate kinase family protein",308.36,{"v":0.0278911972653194,"d":"0.028"},{"v":0.7991784747369745,"d":"0.80"}]
["PACid:16418653","Class II aminoacyl-tRNA and biotin synthetases superfamily protein",214.67,{"v":0.0445835343860925,"d":"0.045"},{"v":0.7991624435096328,"d":"0.80"}]
["PACid:16410367","Ribosomal protein L14",107.55,{"v":0.0484362913368505,"d":"0.048"},{"v":0.7974154238866853,"d":"0.80"}]
["PACid:16411302","alpha/beta-Hydrolases superfamily protein",83.48,{"v":0.0150022035475181,"d":"0.015"},{"v":0.7806232317463758,"d":"0.78"}]
["PACid:16431481","phosphomannomutase",43.6,{"v":0.0380800622342861,"d":"0.038"},{"v":0.7780872061311315,"d":"0.78"}]
["PACid:16420035","nuclear transport factor 2B",88.57,{"v":0.00965039671844514,"d":"0.010"},{"v":0.7760795001591915,"d":"0.78"}]
["PACid:16414185","ATP-dependent caseinolytic (Clp) protease/crotonase family protein",287.02,{"v":4.3656806928164E-3,"d":"0.004"},{"v":0.7508549754732402,"d":"0.75"}]
["PACid:16418595","arginine/serine-rich splicing factor 35",72.74,{"v":0.0490914198841048,"d":"0.049"},{"v":0.7482385141433835,"d":"0.75"}]
["PACid:16428797","glycine-rich RNA-binding protein 3",136.21,{"v":0.0182625872930515,"d":"0.018"},{"v":0.7468800015708994,"d":"0.75"}]
["PACid:16424511","ATP synthase alpha/beta family protein",1236.99,{"v":0.0176321721305999,"d":"0.018"},{"v":0.7397234583036263,"d":"0.74"}]
["PACid:16429306","delta(3,5),delta(2,4)-dienoyl-CoA isomerase 1",45.27,{"v":0.0205788250295854,"d":"0.021"},{"v":0.7351233338589195,"d":"0.74"}]
["PACid:16404188","ABC transporter family protein",79.31,{"v":0.0367877261770886,"d":"0.037"},{"v":0.7321595430242914,"d":"0.73"}]
["PACid:16410178","Cobalamin-independent synthase family protein",1605.03,{"v":0.00913544436643643,"d":"0.009"},{"v":0.7223995265754807,"d":"0.72"}]
["PACid:16425443","2-isopropylmalate synthase 1",183.91,{"v":0.0292827679423749,"d":"0.029"},{"v":0.7114912837843183,"d":"0.71"}]
["PACid:16427747","aconitase 3",595.98,{"v":0.0282584691471437,"d":"0.028"},{"v":0.7082074107348187,"d":"0.71"}]
["PACid:16418905","Aldolase-type TIM barrel family protein",365.53,{"v":0.00651401541569452,"d":"0.007"},{"v":0.7050092390308171,"d":"0.71"}]
["PACid:16413886","Nucleoside diphosphate kinase family protein",340.18,{"v":0.0010306627653186,"d":"0.001"},{"v":0.6942370596859657,"d":"0.69"}]
["PACid:16423481","E3 ubiquitin ligase SCF complex subunit SKP1/ASK1 family protein",123.84,{"v":0.0204439148838543,"d":"0.020"},{"v":0.6911140646839466,"d":"0.69"}]
["PACid:16411383","RNAhelicase-like 8",38.55,{"v":0.0201461683635251,"d":"0.020"},{"v":0.6801885133236197,"d":"0.68"}]
["PACid:16420138","Pseudouridine synthase/archaeosine transglycosylase-like family protein",89.47,{"v":0.0380565737959503,"d":"0.038"},{"v":0.6799322908729082,"d":"0.68"}]
["PACid:16417606","Nascent polypeptide-associated complex (NAC), alpha subunit family protein",302.44,{"v":0.0318700304075135,"d":"0.032"},{"v":0.6797893785225415,"d":"0.68"}]
["PACid:16406013","Plastid-lipid associated protein PAP / fibrillin family protein",114.55,{"v":0.0238654670005102,"d":"0.024"},{"v":0.6767708143896922,"d":"0.68"}]
["PACid:16409816","phytoene desaturase 3",41.46,{"v":0.0417488597477151,"d":"0.042"},{"v":0.665910164104165,"d":"0.67"}]
["PACid:16408660","UDP-glucose 6-dehydrogenase family protein",203.64,{"v":0.0132241819822798,"d":"0.013"},{"v":0.6606750445532671,"d":"0.66"}]
["PACid:16414684","adenine phosphoribosyl transferase 1",190.56,{"v":0.0200892703565339,"d":"0.020"},{"v":0.6604804882633735,"d":"0.66"}]
["PACid:16412214","pyruvate dehydrogenase E1 alpha",135.87,{"v":0.0469806019631975,"d":"0.047"},{"v":0.6541005822951622,"d":"0.65"}]
["PACid:16416636","annexin 5",173.85,{"v":0.0289565343940622,"d":"0.029"},{"v":0.6496881023381109,"d":"0.65"}]
["PACid:16429896","proteasome alpha subunit A1",63.64,{"v":0.0224040065481197,"d":"0.022"},{"v":0.6462061746718519,"d":"0.65"}]
["PACid:16415884","eif4a-2",701.65,{"v":0.019033330634592,"d":"0.019"},{"v":0.6460027346802073,"d":"0.65"}]
["PACid:16410640","translation initiation factor 3B1",172.57,{"v":0.0108827547038133,"d":"0.011"},{"v":0.6378775969720029,"d":"0.64"}]
["PACid:16412527","Small nuclear ribonucleoprotein family protein",42.37,{"v":0.0110661972411624,"d":"0.011"},{"v":0.6347126214343767,"d":"0.63"}]
["PACid:16404756","ssDNA-binding transcriptional regulator",127.65,{"v":0.0218233954513984,"d":"0.022"},{"v":0.6280028764794411,"d":"0.63"}]
["PACid:16412600","Phosphoglucomutase/phosphomannomutase family protein",651.19,{"v":0.00238617863631174,"d":"0.002"},{"v":0.6248503961530444,"d":"0.62"}]
["PACid:16406115","Ribosomal protein S12/S23 family protein",48.56,{"v":0.0177638782502099,"d":"0.018"},{"v":0.623988767853948,"d":"0.62"}]
["PACid:16422265","GTP binding Elongation factor Tu family protein",554.87,{"v":0.0400331144417383,"d":"0.040"},{"v":0.6222607721803453,"d":"0.62"}]
["PACid:16423313","gamma carbonic anhydrase 1",117.74,{"v":0.0095781802030499,"d":"0.010"},{"v":0.617291664532455,"d":"0.62"}]
["PACid:16411975","Ribosomal protein L35Ae family protein",117.63,{"v":0.0300597308487994,"d":"0.030"},{"v":0.6073029977832285,"d":"0.61"}]
["PACid:16419278","phosphoglucomutase",82.81,{"v":0.00316498892183004,"d":"0.003"},{"v":0.5963515112972837,"d":"0.60"}]
["PACid:16407915","Cytochrome C1 family",131.43,{"v":0.0123184628826594,"d":"0.012"},{"v":0.5928966261976704,"d":"0.59"}]
["PACid:16431114","Serine protease inhibitor (SERPIN) family protein",65.7,{"v":0.0158880187586764,"d":"0.016"},{"v":0.5822876763551874,"d":"0.58"}]
["PACid:16404753","ACT domain-containing protein",30.2,{"v":0.0432917694601365,"d":"0.043"},{"v":0.5818225915500072,"d":"0.58"}]
["Down-accumulated proteins"]
["PACid:16426616","kunitz trypsin inhibitor 1",82.22,{"v":0.0432759035228087,"d":"0.043"},{"v":-3.4260585955891907,"d":"-3.43"}]
["PACid:16421897","non-photochemical quenching 1",41.64,{"v":0.00567691985623331,"d":"0.006"},{"v":-2.984678783828949,"d":"-2.98"}]
["PACid:16430895","None",15.11,{"v":0.00288741823949468,"d":"0.003"},{"v":-2.303509511686136,"d":"-2.30"}]
["PACid:16418225","PsbQ-like 2",31.23,{"v":0.0413031936916565,"d":"0.041"},{"v":-1.9565786620041077,"d":"-1.96"}]
["PACid:16425864","DnaJ/Hsp40 cysteine-rich domain superfamily protein",25.92,{"v":0.0164899339399677,"d":"0.016"},{"v":-1.844255175279816,"d":"-1.84"}]
["PACid:16405665","ribulose-bisphosphate carboxylases",188.91,{"v":0.00307429649131907,"d":"0.003"},{"v":-1.6924199979814514,"d":"-1.69"}]
["PACid:16428787","histone deacetylase 5",56.63,{"v":0.0450869911460593,"d":"0.045"},{"v":-1.6358984169199755,"d":"-1.64"}]
["GI:167391804","photosystem I P700 chlorophyll a apoprotein A2 (chloroplast) [Carica papaya]",510.29,{"v":0.00654587317594268,"d":"0.007"},{"v":-0.9047962203365073,"d":"-0.90"}]
["GI:167391836","cytochrome b6 (chloroplast) [Carica papaya]",141.28,{"v":0.0290637163545099,"d":"0.029"},{"v":-0.7903404988929085,"d":"-0.79"}]
["PACid:16406942","Aldolase superfamily protein",336.7,{"v":0.0376381053674589,"d":"0.038"},{"v":-0.6055679580608,"d":"-0.61"}]
["PACid:16415292","tubulin beta-1 chain",270.36,{"v":0.0211106006703625,"d":"0.021"},{"v":-0.6013797749913286,"d":"-0.60"}]
["1Phytozome or NCBI gene identification number."]
["2Phytozome or NCBI gene description."]
["3Quality assurance scores for protein alignment by Progenesis QI."]
["4Analysis of variance (ANOVA) based p value (p≤0.05)."]
["5Log2 fold change of protein abundances comparing PMeV+PMeV2-infected vs. control plants."]

{"sheet":"Supplemental Table S13","index":12,"n_rows":195,"n_cols":5,"rows_kept":195,"merged":[[2,0,2,4],[9,0,9,4],[11,0,11,4],[13,0,13,4],[17,0,17,4],[19,0,19,4],[21,0,21,4],[27,0,27,4],[33,0,33,4],[37,0,37,4],[43,0,43,4],[47,0,47,4],[49,0,49,4],[58,0,58,4],[60,0,60,4],[65,0,65,4],[72,0,72,4],[74,0,74,4],[82,0,82,4],[84,0,84,4],[90,0,90,4],[108,0,108,4],[113,0,113,4],[144,0,144,4],[147,0,147,4],[157,0,157,4],[161,0,161,4],[167,0,167,4],[188,0,188,4],[189,0,189,4],[190,0,190,4],[191,0,191,4],[192,0,192,4],[193,0,193,4],[194,0,194,4]]}
["Supplemental Table S13. Metabolic pathway overview of abundance changed proteins in 7 months post germination (120 days post inoculation) PMeV+PMeV2-infected and control C. papaya leaf samples."]
["Bin Code1","Bin Name2","Protein ID3","Protein Description4","FC5"]
["Photosynthesis"]
["1.1.1.2","PS.lightreaction.photosystem II.PSII polypeptide subunits","PACid:16418225","PsbQ-like 2",-1.957]
["1.1.1.2","PS.lightreaction.photosystem II.PSII polypeptide subunits","PACid:16415072","Photosystem II reaction center PsbP family protein",1.132]
["1.2.6","PS.photorespiration.hydroxypyruvate reductase","PACid:16423092","D-isomer specific 2-hydroxyacid dehydrogenase family protein",1.589]
["1.3.1","PS.calvin cycle.rubisco large subunit","PACid:16405665","ribulose-bisphosphate carboxylases",-1.692]
["1.3.5","PS.calvin cycle.TPI","PACid:16404356","triosephosphate isomerase",1.162]
["1.3.6","PS.calvin cycle.aldolase","PACid:16406942","Aldolase superfamily protein",-0.606]
["Major carbohydrates"]
["2.2.1.5","major CHO metabolism.degradation.sucrose.Susy","PACid:16427103","sucrose synthase 4",0.862]
["Minor carbohydrates"]
[3.5,"minor CHO metabolism.others","PACid:16417615","NAD(P)-linked oxidoreductase superfamily protein",1.026]
["Glycolysis"]
["4.1.3","glycolysis.cytosolic branch.glucose-6-phosphate isomerase","PACid:16418455","Sugar isomerase (SIS) family protein/ Glucose-6-phosphate isomerase / Phosphosaccharomutase",1.154]
["4.1.7","glycolysis.cytosolic branch.triosephosphate isomerase (TPI)","PACid:16404356","triosephosphate isomerase",1.162]
["4.2.14","glycolysis.plastid branch.pyruvate kinase (PK)","PACid:16420148","Pyruvate kinase family protein/ PLASTIDIAL PYRUVATE KINASE 1",1.547]
["Fermentation"]
[5.1,"fermentation.aldehyde dehydrogenase","PACid:16414159","aldehyde dehydrogenase 2C4",1.009]
["Gluconeogenesis/glyoxylate cycle"]
[6.3,"gluconeogenesis / glyoxylate cycle.Malate DH","PACid:16407544","peroxisomal NAD-malate dehydrogenase 1",1.277]
["Oxidative pentose phosphate pathway"]
["7.1.2","OPP.oxidative PP.6-phosphogluconolactonase","PACid:16416408","NagB/RpiA/CoA transferase-like superfamily protein",0.976]
["7.1.3","OPP.oxidative PP.6-phosphogluconate dehydrogenase","PACid:16426375","glyoxylate reductase 1",1.144]
["7.2.2","OPP.non-reductive PP.transaldolase","PACid:16416152","Aldolase superfamily protein",0.913]
["7.2.2","OPP.non-reductive PP.transaldolase","PACid:16418905","Aldolase-type TIM barrel family protein",0.705]
[7.3,"OPP.electron transfer","PACid:16410436","root FNR 1",2.228]
["TCA cycle/organic acid transformations"]
["8.1.1.1","TCA / org transformation.TCA.pyruvate DH.E1","PACid:16429310","Transketolase family protein",0.853]
["8.1.1.1","TCA / org transformation.TCA.pyruvate DH.E1","PACid:16412214","pyruvate dehydrogenase E1 alpha",0.654]
["8.1.3","TCA / org transformation.TCA.aconitase","PACid:16423500","aconitase 1",0.837]
["8.1.3","TCA / org transformation.TCA.aconitase","PACid:16427747","aconitase 3",0.708]
["8.1.6","TCA / org transformation.TCA.succinyl-CoA ligase","PACid:16403829","Succinyl-CoA ligase, alpha subunit",1.161]
["Mitochondrial electron transport/ATP synthesis"]
["9.1.1.5","mitochondrial electron transport / ATP synthesis.NADH-DH.complex I.carbonic anhydrase","PACid:16423313","gamma carbonic anhydrase 1",0.617]
[9.6,"mitochondrial electron transport / ATP synthesis.cytochrome c","PACid:16407915","Cytochrome C1 family",0.593]
[9.9,"mitochondrial electron transport / ATP synthesis.F1-ATPase","PACid:16424511","ATP synthase alpha/beta family protein",0.74]
["Cell wall"]
["10.1.1.1","cell wall.precursor synthesis.NDP sugar pyrophosphorylase.GDP mannose","PACid:16420360","Glucose-1-phosphate adenylyltransferase family protein/ Mannose-1-phosphate guanylyltransferase (GDP) / GDP-mannose pyrophosphorylase",1.867]
["10.1.4","cell wall.precursor synthesis.UGD","PACid:16408660","UDP-glucose 6-dehydrogenase family protein",0.661]
["10.1.7","cell wall.precursor synthesis.GMD","PACid:16423410","NAD(P)-binding Rossmann-fold superfamily protein",1.025]
["10.1.10","cell wall.precursor synthesis.UDP-glucose 4,6-dehydratase","PACid:16416231","nucleotide-rhamnose synthase/epimerase-reductase",1.076]
["10.1.21","cell wall.precursor synthesis.phosphomannomutase","PACid:16431481","phosphomannomutase",0.778]
["Lipid metabolism"]
["11.1.30","lipid metabolism.FA synthesis and FA elongation.pyruvate kinase","PACid:16421200","Pyruvate kinase family protein",0.799]
["11.9.4.9","lipid metabolism.lipid degradation.beta-oxidation.multifunctional","PACid:16427399","Enoyl-CoA hydratase/isomerase family",1.066]
["11.9.4.14","lipid metabolism.lipid degradation.beta-oxidation.enoyl isomerase","PACid:16429306","delta(3,5),delta(2,4)-dienoyl-CoA isomerase 1",0.735]
["Nitrogen metabolism"]
["12.2.2","N-metabolism.ammonia metabolism.glutamine synthetase","PACid:16416361","glutamine synthase clone R1",1.043]
["Amino acid metabolism"]
["13.1.1.2.1","amino acid metabolism.synthesis.central amino acid metabolism.aspartate.aspartate aminotransferase","PACid:16413034","aspartate aminotransferase",1.22]
["13.1.2.2","amino acid metabolism.synthesis.glutamate family.proline","PACid:16420362","delta 1-pyrroline-5-carboxylate synthase 2",1.192]
["13.1.3.4","amino acid metabolism.synthesis.aspartate family.methionine","PACid:16418661","methylthioadenosine nucleosidase 1",1.148]
["13.1.3.4","amino acid metabolism.synthesis.aspartate family.methionine","PACid:16410178","Cobalamin-independent synthase family protein",0.722]
["13.1.4.4.1","amino acid metabolism.synthesis.branched chain group.leucine specific.2-isopropylmalate synthase","PACid:16425443","2-isopropylmalate synthase 1",0.711]
["13.1.7.9","amino acid metabolism.synthesis.histidine.histidinol dehydrogenase","PACid:16408534","histidinol dehydrogenase",1.163]
["13.2.2.3","amino acid metabolism.degradation.glutamate family.arginine","PACid:16410427","urease accessory protein G",1.442]
["13.2.6.3","amino acid metabolism.degradation.aromatic aa.tryptophan","PACid:16414185","ATP-dependent caseinolytic (Clp) protease/crotonase family protein/ 3-HYDROXYISOBUTYRYL-COA HYDROLASE-LIKE PROTEIN 3, MITOCHONDRIAL-RELATED",0.751]
["Sulphur assimilation"]
[14.1,"S-assimilation.ATPS","PACid:16420138","Pseudouridine synthase/archaeosine transglycosylase-like family protein",0.68]
["Secondary metabolism"]
["16.1.4.2","secondary metabolism.isoprenoids.carotenoids.phytoene dehydrogenase","PACid:16409816","phytoene desaturase 3",0.666]
["16.1.4.21","secondary metabolism.isoprenoids.carotenoids.violaxanthin de-epoxidase","PACid:16421897","non-photochemical quenching 1",-2.985]
["16.2.1.10","secondary metabolism.phenylpropanoids.lignin biosynthesis.CAD","PACid:16405261","GroES-like zinc-binding alcohol dehydrogenase family protein",0.963]
["16.2.1.10","secondary metabolism.phenylpropanoids.lignin biosynthesis.CAD","PACid:16425533","cinnamyl alcohol dehydrogenase 9",0.945]
["Stress"]
["20.1.7","stress.biotic.PR-proteins","PACid:16415012","Disease resistance-responsive (dirigent-like protein) family protein",0.99]
["20.1.7.6.1","stress.biotic.PR-proteins.proteinase inhibitors.trypsin inhibitor","PACid:16426616","kunitz trypsin inhibitor 1",-3.426]
["20.2.1","stress.abiotic.heat","PACid:16413063","mitochondrial HSO70 2",0.824]
["20.2.1","stress.abiotic.heat","PACid:16416617","mitochondrion-localized small heat shock protein 23.6",1.745]
["20.2.1","stress.abiotic.heat","PACid:16425960","mitochondrial HSO70 2",1.839]
["20.2.1","stress.abiotic.heat","PACid:16416771","HSP20-like chaperones superfamily protein",1.563]
["Redox"]
[21.5,"redox.peroxiredoxin","PACid:16431407","thioredoxin-dependent peroxidase 1",0.989]
["Nucleotide metabolism"]
["23.1.1.5","nucleotide metabolism.synthesis.pyrimidine.orotate phosphoribosyltransferase","PACid:16414029","uridine 5\\'-monophosphate synthase / UMP synthase (PYRE-F) (UMPS)",1.067]
["23.1.2.8","nucleotide metabolism.synthesis.purine.SAICAR lyase","PACid:16411964","L-Aspartase-like family protein",1.024]
["23.1.3","nucleotide metabolism.synthesis.PRS-PP","PACid:16421709","Phosphoribosyltransferase family protein",1.003]
["23.3.1.1","nucleotide metabolism.salvage.phosphoribosyltransferases.aprt","PACid:16414684","adenine phosphoribosyl transferase 1",0.66]
["23.3.1.3","nucleotide metabolism.salvage.phosphoribosyltransferases.upp","PACid:16422738","uracil phosphoribosyltransferase",1.526]
["23.4.10","nucleotide metabolism.phosphotransfer and pyrophosphatases.nucleoside diphosphate kinase","PACid:16413886","Nucleoside diphosphate kinase family protein",0.694]
["23.4.99","nucleotide metabolism.phosphotransfer and pyrophosphatases.misc","PACid:16422901","pyrophosphorylase 1",0.949]
["C1 metabolism"]
[25.1,"C1-metabolism.glycine hydroxymethyltransferase","PACid:16416992","serine hydroxymethyltransferase 3",1.585]
["Miscellaneous enzyme families"]
[26.1,"misc.misc2","PACid:16410071","alpha/beta-Hydrolases superfamily protein",0.861]
[26.2,"misc.UDP glucosyl and glucoronyl transferases","PACid:16426518","UDP-glucosyl transferase 71B1",1.88]
[26.8,"misc.nitrilases, *nitrile lyases, berberine bridge enzymes, reticuline oxidases, troponine reductases","PACid:16425995","methyl esterase 10",2.369]
[26.9,"misc.glutathione S transferases","PACid:16421573","glutathione S-transferase PHI 9",1.479]
[26.28,"misc.GDSL-motif lipase","PACid:16421838","GDSL-like Lipase/Acylhydrolase superfamily protein",1.332]
["RNA"]
[27.1,"RNA.processing","PACid:16412527","Small nuclear ribonucleoprotein family protein",0.635]
[27.1,"RNA.processing","PACid:16426929","SWAP (Suppressor-of-White-APricot)/surp RNA-binding domain-containing protein",1.812]
["27.1.1","RNA.processing.splicing","PACid:16418595","arginine/serine-rich splicing factor 35",0.748]
["27.1.2","RNA.processing.RNA helicase","PACid:16427467","P-loop containing nucleoside triphosphate hydrolases superfamily protein",1.123]
["27.1.2","RNA.processing.RNA helicase","PACid:16415884","eif4a-2",0.646]
["27.1.2","RNA.processing.RNA helicase","PACid:16414854","DEA(D/H)-box RNA helicase family protein",3.126]
["27.3.30","RNA.regulation of transcription.Trihelix, Triple-Helix transcription factor family","PACid:16429196","ureidoglycine aminohydrolase",2.054]
["27.3.55","RNA.regulation of transcription.HDA","PACid:16428787","histone deacetylase 5",-1.636]
["27.3.67","RNA.regulation of transcription.putative transcription regulator","PACid:16404756","ssDNA-binding transcriptional regulator",0.628]
["27.3.67","RNA.regulation of transcription.putative transcription regulator","PACid:16412697","Alba DNA/RNA-binding protein",1.791]
["27.3.82","RNA.regulation of transcription.plant TF (pbf2)","PACid:16404756","ssDNA-binding transcriptional regulator",0.628]
["27.3.99","RNA.regulation of transcription.unclassified","PACid:16406589","purin-rich alpha 1",0.848]
[27.4,"RNA.RNA binding","PACid:16425539","Splicing factor, CC1-like",0.89]
[27.4,"RNA.RNA binding","PACid:16410388","RNA-binding (RRM/RBD/RNP motifs) family protein",0.859]
[27.4,"RNA.RNA binding","PACid:16404068","ATPase E1",0.844]
[27.4,"RNA.RNA binding","PACid:16428797","glycine-rich RNA-binding protein 3",0.747]
[27.4,"RNA.RNA binding","PACid:16422232","binding to TOMV RNA 1L (long form)",1.135]
["DNA"]
[28.1,"DNA.synthesis/chromatin structure","PACid:16411383","RNAhelicase-like 8",0.68]
["28.1.3","DNA.synthesis/chromatin structure.histone","PACid:16412130","histone H2A 12",1.169]
["28.1.3","DNA.synthesis/chromatin structure.histone","PACid:16427279","gamma histone variant H2AX",1.179]
["28.1.3","DNA.synthesis/chromatin structure.histone","PACid:16428030","gamma histone variant H2AX",1.272]
["Protein"]
["29.1.12","protein.aa activation.aspartate-tRNA ligase","PACid:16418653","Class II aminoacyl-tRNA and biotin synthetases superfamily protein",0.799]
["29.1.20","protein.aa activation.phenylalanine-tRNA ligase","PACid:16423953","phenylalanyl-tRNA synthetase, putative / phenylalanine--tRNA ligase, putative",1.701]
["29.2.1.2.1.7","protein.synthesis.ribosomal protein.eukaryotic.40S subunit.S7","PACid:16416032","Ribosomal protein S7e family protein",0.811]
["29.2.1.2.1.23","protein.synthesis.ribosomal protein.eukaryotic.40S subunit.S23","PACid:16406115","Ribosomal protein S12/S23 family protein",0.624]
["29.2.1.2.2.14","protein.synthesis.ribosomal protein.eukaryotic.60S subunit.L14","PACid:16410367","Ribosomal protein L14",0.797]
["29.2.1.2.2.80","protein.synthesis.ribosomal protein.eukaryotic.60S subunit.P0","PACid:16411947","Ribosomal protein L10 family protein",1.261]
["29.2.1.2.2.81","protein.synthesis.ribosomal protein.eukaryotic.60S subunit.P1","PACid:16412227","60S acidic ribosomal protein family",1.921]
["29.2.1.2.2.535","protein.synthesis.ribosomal protein.eukaryotic.60S subunit.L35A","PACid:16411975","Ribosomal protein L35Ae family protein",0.607]
["29.2.3","protein.synthesis.initiation","PACid:16410640","translation initiation factor 3B1",0.638]
["29.2.3","protein.synthesis.initiation","PACid:16415916","NagB/RpiA/CoA transferase-like superfamily protein",1.204]
["29.2.4","protein.synthesis.elongation","PACid:16417606","Nascent polypeptide-associated complex (NAC), alpha subunit family protein",0.68]
["29.2.4","protein.synthesis.elongation","PACid:16428003","GTP binding Elongation factor Tu family protein",1.196]
["29.2.4","protein.synthesis.elongation","PACid:16422265","GTP binding Elongation factor Tu family protein",0.622]
["29.3.1","protein.targeting.nucleus","PACid:16425809","Nuclear transport factor 2 (NTF2) family protein with RNA binding (RRM-RBD-RNP motifs) domain",1.353]
["29.3.1","protein.targeting.nucleus","PACid:16420035","nuclear transport factor 2B",0.776]
["29.3.4.3","protein.targeting.secretory pathway.vacuole","PACid:16425098","gamma vacuolar processing enzyme",1.856]
[29.4,"protein.postranslational modification","PACid:16411641","MAP kinase 4",2.138]
["29.4.1.57","protein.postranslational modification.kinase.receptor like cytoplasmatic kinase VII","PACid:16425955","Leucine-rich repeat protein kinase family protein",1.303]
["29.5.1","protein.degradation.subtilases","PACid:16428853","subtilisin-like serine protease 3",1.58]
["29.5.5","protein.degradation.serine protease","PACid:16431114","Serine protease inhibitor (SERPIN) family protein",0.582]
["29.5.11.4.3.1","protein.degradation.ubiquitin.E3.SCF.SKP","PACid:16423481","E3 ubiquitin ligase SCF complex subunit SKP1/ASK1 family protein / S-phase kinase-associated protein 1 (SKP1, CBF3D)",0.691]
["29.5.11.20","protein.degradation.ubiquitin.proteasom","PACid:16405150","AAA-type ATPase family protein / 26S proteasome regulatory subunit T4 (PSMC6, RPT4)",0.802]
["29.5.11.20","protein.degradation.ubiquitin.proteasom","PACid:16429896","proteasome alpha subunit A1 (PSMA6)",0.646]
["29.5.11.20","protein.degradation.ubiquitin.proteasom","PACid:16418604","proteasome alpha subunit D2 / 20S proteasome subunit alpha 4 (PSMA7)",0.845]
["29.5.11.20","protein.degradation.ubiquitin.proteasom","PACid:16429356","Mov34/MPN/PAD-1 family protein / 26S proteasome regulatory subunit N11 (PSMD14, RPN11, POH1)",2.241]
["29.5.11.20","protein.degradation.ubiquitin.proteasom","PACid:16410318","RP non-ATPase subunit 8A / 26S proteasome regulatory subunit N8 (PSMD7, RPN8)",1.325]
["29.5.11.20","protein.degradation.ubiquitin.proteasom","PACid:16424190","proteasome beta subunit C1 / 20S proteasome subunit beta 3 (PSMB3)",0.904]
["29.5.11.20","protein.degradation.ubiquitin.proteasom","PACid:16412645","regulatory particle triple-A ATPase 3 / 26S proteasome regulatory subunit T3 (PSMC4, RPT3)",1.275]
["29.5.11.20","protein.degradation.ubiquitin.proteasom","PACid:16423462","proteasome alpha subunit D2 / 20S proteasome, regulatory subunit alpha type PSMA5/PUP2 // 20S proteasome, regulatory subunit alpha type PSMA2/PRE8",1.599]
[29.6,"protein.folding","PACid:16429335","TCP-1/cpn60 chaperonin family protein",1.297]
["Signalling"]
[30.7,"signalling.14-3-3 proteins","PACid:16417130","general regulatory factor 8",0.818]
[30.7,"signalling.14-3-3 proteins","PACid:16418327","general regulatory factor 11",2.227]
["Cell"]
[31.1,"cell.organisation","PACid:16406013","Plastid-lipid associated protein PAP / fibrillin family protein",0.677]
[31.1,"cell.organisation","PACid:16415292","tubulin beta-1 chain",-0.601]
[31.1,"cell.organisation","PACid:16416636","annexin 5",0.65]
[31.1,"cell.organisation","PACid:16427501","actin-11",1.153]
[31.2,"cell.division","PACid:16406784","homolog of bacterial cytokinesis Z-ring protein FTSZ 1-1",1.024]
[31.2,"cell.division","PACid:16407928","prohibitin 3",0.92]
[31.4,"cell.vesicle transport","PACid:16420664","Adaptor protein complex AP-2, alpha subunit",2.867]
[31.4,"cell.vesicle transport","PACid:16416941","clathrin adaptor complexes medium subunit family protein",0.859]
[31.4,"cell.vesicle transport","PACid:16416071","Coatomer epsilon subunit",0.899]
["Development"]
[33.99,"development.unspecified","PACid:16416747","transducin family protein / WD-40 repeat family protein",1.584]
[33.99,"development.unspecified","PACid:16425864","DnaJ/Hsp40 cysteine-rich domain superfamily protein",-1.844]
[33.99,"development.unspecified","PACid:16428415","ARF-GAP domain 8",1.877]
["Transport"]
[34.1,"transport.p- and v-ATPases","PACid:16425372","vacuolar ATP synthase subunit C (VATC) / V-ATPase C subunit / vacuolar proton pump C subunit (DET3)",0.895]
["34.1.1","transport.p- and v-ATPases.H+-transporting two-sector ATPase","PACid:16412903","ATPase, V1 complex, subunit B protein",0.948]
[34.2,"transport.sugars","PACid:16428900","voltage dependent anion channel 4",1.09]
[34.16,"transport.ABC transporters and multidrug resistance systems","PACid:16404188","ABC transporter family protein",0.732]
[34.2,"transport.porins","PACid:16423409","voltage dependent anion channel 2",0.945]
["Not assigned"]
[35.1,"not assigned.no ontology","PACid:16413596","KH domain-containing protein",1.149]
[35.1,"not assigned.no ontology","PACid:16404753","ACT domain-containing protein",0.582]
[35.1,"not assigned.no ontology","PACid:16411302","alpha/beta-Hydrolases superfamily protein",0.781]
[35.1,"not assigned.no ontology","PACid:16416453","SPFH/Band 7/PHB domain-containing membrane-associated protein family",1.198]
["35.1.5","not assigned.no ontology.pentatricopeptide (PPR) repeat-containing protein","PACid:16429423","pentatricopeptide (PPR) repeat-containing protein",1.436]
["35.1.5","not assigned.no ontology.pentatricopeptide (PPR) repeat-containing protein","PACid:16416137","tetraticopeptide domain-containing thioredoxin",0.821]
[35.2,"not assigned.unknown","PACid:16412620","None",0.905]
[35.2,"not assigned.unknown","PACid:16419957","Nucleotide-diphospho-sugar transferases superfamily protein",1.029]
[35.2,"not assigned.unknown","PACid:16412600","Phosphoglucomutase/phosphomannomutase family protein",0.625]
[35.2,"not assigned.unknown","PACid:16427505","Plastid-lipid associated protein PAP / fibrillin family protein",0.84]
[35.2,"not assigned.unknown","PACid:16427150","None",1.649]
[35.2,"not assigned.unknown","PACid:16409578","None",0.995]
[35.2,"not assigned.unknown","PACid:16425886","Alba DNA/RNA-binding protein",0.821]
[35.2,"not assigned.unknown","PACid:16407265","None",1.182]
[35.2,"not assigned.unknown","PACid:16426114","None",2.518]
[35.2,"not assigned.unknown","PACid:16409579","chloroplast outer envelope protein 37",1.369]
[35.2,"not assigned.unknown","PACid:16430895","None",-2.304]
[35.2,"not assigned.unknown","PACid:16411051","Tetratricopeptide repeat (TPR)-like superfamily protein",1.708]
[35.2,"not assigned.unknown","PACid:16419278","phosphoglucomutase",0.596]
[35.2,"not assigned.unknown","PACid:16425167","alpha/beta-Hydrolases superfamily protein",4.181]
["1MapMan Bin Code."]
["2MapMan Bin Name."]
["3Phytozome gene identification number."]
["4Phytozome gene description."]
["5Log2 fold change of protein abundances comparing PMeV+PMeV2-infected vs. control plants."]
["Red - Up-accumulated"]
["Green - Down-accumulated"]

{"sheet":"Supplemental Table 14","index":13,"n_rows":26,"n_cols":5,"rows_kept":26,"merged":[[0,0,0,4],[2,0,2,4],[14,0,14,4],[21,0,21,4],[22,0,22,4],[23,0,23,4],[24,0,24,4],[25,0,25,4]]}
["Supplemental Table S14. Proteins differently modulated in 9 months post germination (180 days post inoculation) PMeV+PMeV2-infected C. papaya leaf."]
["Phytozome/NCBI Accession1","Description2","Confidence score3","Anova (p)4","FC5"]
["Up-accumulated proteins"]
["PACid:16421621","ATP-dependent caseinolytic (Clp) protease/crotonase family protein",42.8,{"v":0.0250468219408078,"d":"0.025"},{"v":2.1283032536778306,"d":"2.13"}]
["PACid:16426826","Cyclophilin-like peptidyl-prolyl cis-trans isomerase family protein",54.19,{"v":0.0254182500880683,"d":"0.025"},{"v":2.1250278079978835,"d":"2.13"}]
["PACid:16409552","fumarase 1",27.17,{"v":0.0190214811134742,"d":"0.019"},{"v":1.8631299502599297,"d":"1.86"}]
["PACid:16412603","ENTH/ANTH/VHS superfamily protein",14.61,{"v":0.0425083233200432,"d":"0.043"},{"v":1.5578358462791486,"d":"1.56"}]
["PACid:16418772","Glycosyl hydrolase superfamily protein",83.32,{"v":0.0102772842093296,"d":"0.010"},{"v":1.498767095101808,"d":"1.50"}]
["PACid:16405045","Dihydroneopterin aldolase",86.91,{"v":0.0274425945867161,"d":"0.027"},{"v":1.435565867803468,"d":"1.44"}]
["PACid:16407797","GroES-like zinc-binding alcohol dehydrogenase family protein",44.76,{"v":0.0494092774672563,"d":"0.049"},{"v":1.149076975725092,"d":"1.15"}]
["PACid:16404068","ATPase E1",43.25,{"v":0.0229937655628984,"d":"0.023"},{"v":1.1422869069630996,"d":"1.14"}]
["PACid:16422232","binding to TOMV RNA 1L (long form)",31.85,{"v":0.0466315397611579,"d":"0.047"},{"v":0.9193088357756067,"d":"0.92"}]
["PACid:16404260","Cleavage and polyadenylation specificity factor (CPSF) A subunit protein",78.4,{"v":0.0447395200920149,"d":"0.045"},{"v":0.8054510279438171,"d":"0.81"}]
["PACid:16426651","succinate dehydrogenase 5",118.62,{"v":0.0354035283094171,"d":"0.035"},{"v":0.7021807138957462,"d":"0.70"}]
["Down-accumulated proteins"]
["PACid:16406769","PLC-like phosphodiesterase family protein",118.14,{"v":0.00736024739989849,"d":"0.007"},{"v":-1.880527388216548,"d":"-1.88"}]
["PACid:16428931","P-loop containing nucleoside triphosphate hydrolases superfamily protein",41.36,{"v":0.00975117093163236,"d":"0.010"},{"v":-1.5041784915266612,"d":"-1.50"}]
["PACid:16432121","tryptophan biosynthesis 1",32.85,{"v":3.18977359902606E-3,"d":"0.003"},{"v":-1.0089370439234078,"d":"-1.01"}]
["PACid:16423549","None",66.82,{"v":0.0243367200391345,"d":"0.024"},{"v":-0.8084744310054967,"d":"-0.81"}]
["PACid:16419807","alternative oxidase 2",38.33,{"v":0.0319727773067133,"d":"0.032"},{"v":-0.7732117967869065,"d":"-0.77"}]
["PACid:16424172","thylakoidal ascorbate peroxidase",73.69,{"v":0.00483569210212575,"d":"0.005"},{"v":-0.5942084170698734,"d":"-0.59"}]
["1Phytozome or NCBI gene identification number."]
["2Phytozome or NCBI gene description."]
["3Quality assurance scores for protein alignment by Progenesis QI."]
["4Analysis of variance (ANOVA) based p value (p≤0.05)."]
["5Log2 fold change of protein abundances comparing PMeV+PMeV2-infected vs. control plants."]

{"sheet":"Supplemental Table S15","index":14,"n_rows":38,"n_cols":5,"rows_kept":38,"merged":[[2,0,2,4],[4,0,4,4],[6,0,6,4],[8,0,8,4],[11,0,11,4],[14,0,14,4],[16,0,16,4],[18,0,18,4],[21,0,21,4],[25,0,25,4],[27,0,27,4],[31,0,31,4],[32,0,32,4],[33,0,33,4],[34,0,34,4],[35,0,35,4],[36,0,36,4],[37,0,37,4]]}
["Supplemental Table S15. Metabolic pathway overview of abundance changed proteins in 9 months post germination (180 days post inoculation) PMeV+PMeV2-infected and control C. papaya leaf samples."]
["Bin Code1","Bin Name2","Protein ID3","Protein Description4","FC5"]
["Photosynthesis"]
["1.3.13","PS.calvin cycle.rubisco interacting","PACid:16428931","P-loop containing nucleoside triphosphate hydrolases superfamily protein",-1.504]
["TCA cycle/organic acid transformations"]
["8.1.8","TCA / org transformation.TCA.fumarase","PACid:16409552","fumarase 1",1.863]
["Mitochondrial electron transport/ATP synthesis"]
[9.4,"mitochondrial electron transport / ATP synthesis.alternative oxidase","PACid:16419807","alternative oxidase 2",-0.773]
["Lipid metabolism"]
["11.9.3.3","lipid metabolism.lipid degradation.lysophospholipases.glycerophosphodiester phosphodiesterase","PACid:16406769","PLC-like phosphodiesterase family protein",-1.881]
["11.9.4.3","lipid metabolism.lipid degradation.beta-oxidation.enoyl CoA hydratase","PACid:16421621","ATP-dependent caseinolytic (Clp) protease/crotonase family protein",2.128]
["Amino acid metabolism"]
["13.1.6.5.2","amino acid metabolism.synthesis.aromatic aa.tryptophan.anthranilate phosphoribosyltransferase","PACid:16432121","tryptophan biosynthesis 1",-1.009]
["13.2.6.3","amino acid metabolism.degradation.aromatic aa.tryptophan","PACid:16421621","ATP-dependent caseinolytic (Clp) protease/crotonase family protein",2.128]
["Redox"]
["21.2.1","redox.ascorbate and glutathione.ascorbate","PACid:16424172","thylakoidal ascorbate peroxidase",-0.594]
["C1 metabolism"]
[25.9,"C1-metabolism.dihydroneopterin aldolase","PACid:16405045","Dihydroneopterin aldolase",1.436]
["Miscellaneous enzyme families"]
["26.4.1","misc.beta 1,3 glucan hydrolases.glucan endo-1,3-beta-glucosidase","PACid:16418772","Glycosyl hydrolase superfamily protein",1.499]
[26.7,"misc.oxidases - copper, flavone etc","PACid:16407797","GroES-like zinc-binding alcohol dehydrogenase family protein",1.149]
["RNA"]
["27.1.1","RNA.processing.splicing","PACid:16404260","Cleavage and polyadenylation specificity factor (CPSF) A subunit protein",0.805]
[27.4,"RNA.RNA binding","PACid:16404068","ATPase E1",1.142]
[27.4,"RNA.RNA binding","PACid:16422232","binding to TOMV RNA 1L (long form)",0.919]
["Cell"]
["31.3.1","cell.cycle.peptidylprolyl isomerase","PACid:16426826","Cyclophilin-like peptidyl-prolyl cis-trans isomerase family protein",2.125]
["Not assigned"]
["35.1.21","not assigned.no ontology.epsin N-terminal homology (ENTH) domain-containing protein","PACid:16412603","ENTH/ANTH/VHS superfamily protein",1.558]
[35.2,"not assigned.unknown","PACid:16426651","succinate dehydrogenase 5",0.702]
[35.2,"not assigned.unknown","PACid:16423549","None",-0.808]
["1MapMan Bin Code."]
["2MapMan Bin Name."]
["3Phytozome gene identification number."]
["4Phytozome gene description."]
["5Log2 fold change of protein abundances comparing PMeV+PMeV2-infected vs. control plants."]
["Red - Up-accumulated"]
["Green - Down-accumulated"]