{"text_format":"3","workbook":"xlsx","n_sheets":6,"sheets":["Supplementary Table1","Supplementary Table2","Supplementary Table3","Supplementary Table4","Supplementary Table5","Supplementary Table6"],"not_rendered":{"defined_names":1},"read":"whole","date_system":"1900"}

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["Supplementary Table 1. The expression profle of the 16138 genes in the datasets of GSE16561 combined with GSE58294."]
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{"sheet":"Supplementary Table2","index":1,"n_rows":110,"n_cols":10,"rows_kept":110,"merged":[[0,0,0,9]]}
["Supplementary Table 2. The m6A RNA methylation modification patterns mediated by 8 key m6A regulators in ischaemic stroke samples."]
["ID","METTL3","WTAP","RBM15B","CBLL1","YTHDF1","YTHDF3","HNRNPA2B1","ALKBH5","m6Acluster"]
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{"sheet":"Supplementary Table3","index":2,"n_rows":25,"n_cols":156,"rows_kept":25,"merged":[[0,0,0,155]]}
["Supplementary Table3. The immune microenvironment characteristics in control and ischaemic stroke samples."]
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{"sheet":"Supplementary Table4","index":3,"n_rows":52,"n_cols":156,"rows_kept":52,"merged":[[0,0,0,155]]}
["Supplementary Table 4. The results of gene set variation analysis enrichment analysis."]
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["HALLMARK_ALLOGRAFT_REJECTION",0.7223385,0.764421715,0.754981483,0.755713444,0.765133783,0.742262131,0.735858619,0.766404544,0.763953253,0.734768471,0.725131832,0.728343371,0.751478215,0.725962013,0.732363254,0.724090599,0.734461259,0.719847426,0.718683489,0.725633477,0.753187898,0.732856778,0.732752279,0.732748117,0.74166302,0.76561828,0.777935674,0.776539861,0.709944175,0.765927067,0.771075394,0.762016423,0.759427517,0.769110309,0.760631863,0.743921172,0.740316111,0.740348474,0.730547367,0.770917481,0.754543562,0.741195709,0.736141175,0.750047529,0.761938212,0.70329216,0.749755263,0.766461568,0.68888823,0.679636722,0.744302697,0.714719833,0.744048676,0.726750475,0.664601926,0.770639476,0.741639502,0.683028736,0.691799067,0.747595387,0.745185839,0.723887167,0.73235504,0.759225968,0.737506598,0.684111884,0.687248836,0.688847346,0.743708427,0.697211324,0.695255788,0.728465709,0.68837321,0.624374472,0.748469096,0.722299096,0.735062682,0.679427184,0.731574938,0.723568729,0.750170562,0.729438443,0.745456679,0.6630336,0.778471637,0.677041974,0.751876893,0.69825753,0.75855444,0.743664629,0.767941346,0.739328247,0.75193616,0.695441441,0.754660624,0.717878843,0.691036717,0.711096622,0.734219158,0.709141689,0.7379505,0.71050883,0.734352119,0.732161351,0.708295447,0.69199144,0.669772966,0.755992009,0.746322603,0.742536213,0.656424159,0.773454156,0.688507935,0.74523089,0.674005557,0.735038989,0.742471504,0.697440603,0.78276116,0.73178507,0.712605351,0.753787371,0.748820543,0.714926859,0.666247592,0.639522656,0.665935079,0.748893743,0.72660247,0.720285296,0.707921891,0.696039465,0.728591035,0.753736356,0.76515425,0.701135665,0.739491809,0.634574022,0.771588524,0.717377104,0.753874541,0.707689193,0.758352291,0.793423062,0.736043515,0.712117294,0.748470453,0.696912193,0.626759369,0.69393407,0.707854782,0.733001877,0.729924479,0.723163603,0.687492635]
["HALLMARK_SPERMATOGENESIS",0.170394807,0.207993416,0.159125148,0.185857936,0.188865605,0.194849856,0.199496252,0.194529959,0.236829624,0.191475123,0.180922715,0.223643782,0.220170713,0.140929993,0.192420387,0.115438009,0.148379674,0.157511264,0.173275722,0.260764718,0.15197488,0.167444426,0.181801386,0.217017929,0.209313617,0.265547306,0.210302285,0.199846975,0.280453228,0.216111626,0.144037551,0.182841029,0.250281746,0.28762579,0.187328228,0.235526746,0.197439277,0.269884743,0.221217817,0.250568714,0.189605525,0.184965348,0.2170854,0.236046227,0.159040829,0.206025623,0.260731059,0.160955939,0.187425327,0.248511918,0.158787798,0.17527162,0.159953645,0.210942218,0.229457097,0.158382674,0.174703933,0.234295327,0.197880034,0.145394086,0.21767678,0.239381451,0.202161113,0.247365216,0.195291203,0.155070505,0.165571768,0.230748268,0.245831899,0.210196168,0.155004165,0.221616398,0.176643978,0.278304798,0.151838518,0.162968657,0.233568793,0.20854791,0.19409072,0.192804214,0.163103114,0.176581798,0.133399261,0.270588061,0.212070087,0.192830306,0.174912272,0.17553956,0.132582089,0.230521334,0.131798445,0.269373191,0.150301611,0.186425292,0.146476858,0.206018718,0.189524439,0.130941369,0.191799989,0.143073746,0.212727653,0.273779131,0.189356385,0.136088634,0.193974597,0.149332982,0.240148069,0.25188213,0.141697085,0.182229029,0.170802331,0.139635699,0.151596151,0.150411621,0.145683773,0.187482142,0.281858715,0.313315518,0.211840269,0.180030131,0.234222831,0.117635175,0.148075942,0.188834692,0.168484028,0.277069481,0.171401002,0.182948154,0.149397422,0.169299694,0.167209644,0.17018316,0.141452306,0.178447402,0.241203354,0.198550076,0.20954086,0.154637746,0.148270393,0.169106792,0.217288862,0.14385575,0.162558411,0.218777436,0.247835994,0.176012836,0.186049778,0.158548333,0.231951761,0.185703565,0.20560459,0.143606887,0.141295783,0.127375322,0.205535021]
["HALLMARK_KRAS_SIGNALING_UP",0.603263579,0.611017971,0.65637211,0.58812243,0.647031914,0.642196481,0.592214097,0.583728291,0.690293676,0.677989159,0.648219845,0.623495751,0.623676044,0.668217906,0.603368064,0.656228852,0.635904254,0.633137415,0.626324395,0.617559004,0.625055967,0.65396083,0.625687761,0.613982169,0.683314441,0.687601058,0.628784326,0.694779412,0.59313612,0.685181235,0.750616627,0.647893972,0.682399998,0.686149425,0.664425004,0.720739868,0.676301765,0.678302,0.700468965,0.69081696,0.627145223,0.729375898,0.664032852,0.706385701,0.658603741,0.68345852,0.582910159,0.679077652,0.668391255,0.671201152,0.67543827,0.704833505,0.732921698,0.739134064,0.742413634,0.673642664,0.722547355,0.725672792,0.75146335,0.640400097,0.718154416,0.653342031,0.737925105,0.688155058,0.713184587,0.72522852,0.722498063,0.718805196,0.691116776,0.67003091,0.701099759,0.612129602,0.701503333,0.705541414,0.683565851,0.721325916,0.681289276,0.650367622,0.694440398,0.738867338,0.691625762,0.721141965,0.657353682,0.705631563,0.734658371,0.731772164,0.757674281,0.622779052,0.610027609,0.659998262,0.712119467,0.720812594,0.672692765,0.733241087,0.727422633,0.65669458,0.71280848,0.652856572,0.66089377,0.710596623,0.682096533,0.648525173,0.720498337,0.689570665,0.699802557,0.655983907,0.717628094,0.63633581,0.654057262,0.74002572,0.722897621,0.666037351,0.6371027,0.652178612,0.710429083,0.714169612,0.652507054,0.637292007,0.70629195,0.719961077,0.720408171,0.719629917,0.691685923,0.701890061,0.63130499,0.710047135,0.729903151,0.722560678,0.653546146,0.697760418,0.666826321,0.679740055,0.671131603,0.679575186,0.733004165,0.628033532,0.708027797,0.653924047,0.66624599,0.696618881,0.69210787,0.653725181,0.690683825,0.743519794,0.695674306,0.727508831,0.692951657,0.644102557,0.736853189,0.69889172,0.676678285,0.659659001,0.723147221,0.679718448,0.690093923]
["HALLMARK_KRAS_SIGNALING_DN",0.614777279,0.258286378,0.366243301,0.39398673,0.381424564,0.258064133,0.460988194,0.147366447,0.286950048,0.186382722,0.261634502,0.436360692,0.420080852,0.222594289,0.430053315,0.290091542,0.250067638,0.51759325,0.309508477,0.231670178,0.239550793,0.207308523,0.36457577,0.290277819,0.409007211,0.37668681,0.571194648,0.655399992,0.33363535,0.37050348,0.626571221,0.287271986,0.381655848,0.527720331,0.416290826,0.44414467,0.506922626,0.526993238,0.374496353,0.366348339,0.397925224,0.521247157,0.426934318,0.420668139,0.564643921,0.498020235,0.403885901,0.480631248,0.394372677,0.464028261,0.384395192,0.424323176,0.51841824,0.429187065,0.501429232,0.476762049,0.320236427,0.416476357,0.227626553,0.230996396,0.310937267,0.28553591,0.304635003,0.140140518,0.545980795,0.485783901,0.620514382,0.354505091,0.48543817,0.493647371,0.312357721,0.264723672,0.591399661,0.385729246,0.569059791,0.565428484,0.14443681,0.349359191,0.29324712,0.392801373,0.600754398,0.447952855,0.44854395,0.333301049,0.348424539,0.372049809,0.545265062,0.566441416,0.460092155,0.241246813,0.421265919,0.374547248,0.574676645,0.381381097,0.485967111,0.391342625,0.357374024,0.070941308,0.355066259,0.170456644,0.29119747,0.072484901,0.386767556,0.490204171,0.418843714,0.37594447,0.415994513,0.330967551,0.355997003,0.548589878,0.325727939,0.382055306,0.222586901,0.354827311,0.294256884,0.294833318,0.284423878,0.089077921,0.397461627,0.502169467,0.387622488,0.575711026,0.523952181,0.323355924,0.429940033,0.456387067,0.349812937,0.330804147,0.350066808,0.438702713,0.488418426,0.250494961,0.496233621,0.401308514,0.420092983,0.571713004,0.583645502,0.185910217,0.311210071,0.29873833,0.165359554,0.314232929,0.154841915,0.330832218,0.264724679,0.52778851,0.347313387,0.319117514,0.440313156,0.260182728,0.383095855,0.342325575,0.499713718,0.462540296,0.26866668]
["HALLMARK_PANCREAS_BETA_CELLS",0.48299906,0.6118238,0.66839604,0.492415442,0.649733459,0.603482933,0.580034372,0.547235038,0.626514622,0.501873727,0.68892503,0.599337269,0.605335687,0.700213511,0.684279851,0.721066548,0.708027127,0.609125355,0.614065786,0.697210694,0.598046753,0.564643621,0.562947029,0.593512884,0.620380987,0.632458371,0.575629939,0.621427245,0.608910753,0.592922962,0.622181869,0.679926427,0.600620484,0.631187751,0.533560092,0.598802004,0.567164728,0.636962311,0.528008548,0.626726387,0.603209568,0.600798051,0.630339241,0.635769771,0.578224296,0.555207188,0.652579037,0.554621298,0.501242167,0.528942179,0.534473348,0.500864378,0.685180335,0.660989914,0.58704908,0.606985962,0.587600057,0.502348189,0.665544417,0.718429638,0.568835926,0.626869452,0.505777995,0.619908557,0.692382195,0.70916202,0.650322968,0.637336379,0.728428587,0.584646729,0.592140822,0.730653757,0.632437786,0.49888491,0.56450586,0.600516158,0.658948587,0.488100464,0.626964422,0.57401766,0.487940098,0.745367572,0.573750993,0.475690849,0.609674292,0.678127613,0.589866963,0.525597374,0.538186982,0.716481001,0.624629071,0.676938545,0.572996982,0.483924357,0.625127242,0.668926116,0.598468346,0.609495562,0.583588865,0.632096233,0.595255356,0.616325954,0.63525087,0.636550285,0.577364516,0.630069746,0.603058193,0.644946474,0.559589187,0.59712412,0.583361768,0.600360472,0.594489956,0.611093485,0.618661742,0.596710423,0.580350362,0.608992405,0.619837717,0.553025349,0.575939486,0.591868918,0.663756279,0.573870676,0.563312679,0.506882362,0.536627979,0.593624827,0.611173258,0.607770054,0.567244318,0.598930663,0.686433774,0.637123781,0.630721162,0.56178601,0.387934508,0.569535489,0.610254567,0.617893,0.677497387,0.511720093,0.614931901,0.6413924,0.67775224,0.615415667,0.639257281,0.58505505,0.541466261,0.55379424,0.5750511,0.496013815,0.655873985,0.642105974,0.697774341]

{"sheet":"Supplementary Table5","index":4,"n_rows":324,"n_cols":4,"rows_kept":324,"merged":[[0,0,0,3]]}
["Supplementary Table 5. The GS values as well as corresponding p values of 636 genes associated with neutrophil in the turquoise module."]
["geneSymbol","moduleColor","GS.ChusterB","p.GS.ChusterB"]
["ABCA1","black",0.303000312082479,0.000126963545560851]
["ABHD5","black",0.294944454829033,0.000194904589042503]
["ACSL1","black",0.571553429911952,{"v":8.04462918160111e-15,"d":"8.04E-15"}]
["ACTR3","black",0.538127673448793,{"v":5.15491046516934e-13,"d":"5.15E-13"}]
["ADAM17","black",0.371977875112652,{"v":1.88156259469369e-06,"d":"1.88E-06"}]
["ADGRE3","black",0.0880968981618486,0.275695393901589]
["ADH4","black",0.239796955921641,0.00265357281743394]
["ADI1","black",0.28786195167632,0.000281200518410009]
["AGTPBP1","black",0.632697307215623,{"v":1.03565618250609E-18,"d":"1.04E-18"}]
["ALCAM","black",0.443686347495034,{"v":7.37343546321976e-09,"d":"7.37E-09"}]
["ALPP","black",0.298878532743976,1.58342918701114E-4]
["ANKRD44","black",0.409389105502749,{"v":1.22805161472089e-07,"d":"1.23E-07"}]
["ANP32A","black",0.50765994897986,{"v":1.5634242222252E-11,"d":"1.56E-11"}]
["ANTXR2","black",0.119930904518581,0.137170217656486]
["ANXA2P1","black",0.179876407159708,0.0251158832464134]
["ANXA3","black",0.246699857198616,0.00197144636930681]
["AOC4P","black",0.224442399508987,0.00499156383655593]
["ARFGEF1","black",0.584285588725042,{"v":1.45242871696234e-15,"d":"1.45E-15"}]
["ARPC5","black",0.485080428614677,{"v":1.58975737531412e-10,"d":"1.59E-10"}]
["ARRDC4","black",0.28300538377816,0.000359584058918451]
["ATG3","black",0.466141943872781,{"v":9.80244486693359e-10,"d":"9.80E-10"}]
["ATP11B","black",0.502251961010303,{"v":2.76739185290707E-11,"d":"2.77E-11"}]
["ATP6V1A","black",0.24861295898243,0.00181295523031493]
["ATXN1","black",0.328997809714797,{"v":2.91770363329241e-05,"d":"2.92E-05"}]
["B3GNT5","black",0.630739263967853,{"v":1.42328614189049E-18,"d":"1.42E-18"}]
["B4GALT5","black",0.19874181092144,0.0131726073290932]
["BCL2A1","black",0.503760859904695,{"v":2.36218620161184E-11,"d":"2.36E-11"}]
["BEST1","black",0.141955819418437,0.0780753943298805]
["BLOC1S6","black",0.483242503949456,{"v":1.90602818021567e-10,"d":"1.91E-10"}]
["C19orf24","black",-0.533924388357953,{"v":8.42468761770632e-13,"d":"8.42E-13"}]
["C1D","black",0.570286911594202,{"v":9.49979262776067E-15,"d":"9.50E-15"}]
["C1GALT1","black",0.543954475262156,{"v":2.57961821891543e-13,"d":"2.58E-13"}]
["C3orf62","black",0.0398175858011599,0.622784804722579]
["C6orf62","black",0.499771338481034,{"v":3.58408168474996e-11,"d":"3.58E-11"}]
["CAMK1","black",-0.502452272972623,{"v":2.70995650208979E-11,"d":"2.71E-11"}]
["CAMK1G","black",0.213943043584928,0.0075169164973266]
["CARD16","black",0.361276763152759,{"v":3.86687941395906e-06,"d":"3.87E-06"}]
["CARS2","black",0.276199683822804,0.000503766835203349]
["CAT","black",0.210330225829311,0.00861803627770529]
["CBL","black",0.265723414782089,0.000832562408433101]
["CCBE1","black",0.262657679769159,0.000960802351313222]
["CCDC126","black",0.536214401553864,{"v":6.45198066450475e-13,"d":"6.45E-13"}]
["CCNG2","black",0.676145777956813,{"v":4.75522865869567e-22,"d":"4.76E-22"}]
["CCP110","black",0.521918146591777,{"v":3.30330827786113e-12,"d":"3.30E-12"}]
["CCPG1","black",0.459653430210933,{"v":1.78277919312968e-09,"d":"1.78E-09"}]
["CD55","black",0.450466898423959,{"v":4.07107869259625e-09,"d":"4.07E-09"}]
["CD58","black",0.619685846243328,{"v":8.21643450243568e-18,"d":"8.22E-18"}]
["CDK19","black",0.18035219683672,0.0247271638244411]
["CDK5R1","black",0.512141693538797,{"v":9.66567949009777e-12,"d":"9.67E-12"}]
["CDKN1B","black",0.682430413271442,{"v":1.40130782614939E-22,"d":"1.40E-22"}]
["CHD1","black",0.621074167345855,{"v":6.61766881960361e-18,"d":"6.62E-18"}]
["CHIC2","black",0.0952546565604495,0.238400421898018]
["CHSY1","black",0.590347924159519,{"v":6.26029872140826e-16,"d":"6.26E-16"}]
["CLEC7A","black",0.520625722041551,{"v":3.81458020896982e-12,"d":"3.81E-12"}]
["CLK4","black",0.537934391487314,{"v":5.27346211427077e-13,"d":"5.27E-13"}]
["CLTC","black",0.175506764051731,0.0289374023508452]
["CNBP","black",0.553925915107028,{"v":7.64486105014975e-14,"d":"7.64E-14"}]
["CNEP1R1","black",0.613740505440709,{"v":2.05075513780886e-17,"d":"2.05E-17"}]
["CNGB1","black",0.245083723780436,0.0021150366550449]
["CNIH4","black",0.282368178530902,0.000371251983601918]
["COG3","black",0.56585372964236,{"v":1.69062018650234E-14,"d":"1.69E-14"}]
["CPD","black",0.228238910175611,4.28540688150495E-3]
["CPPED1","black",0.32251664729834,{"v":4.26366236504657e-05,"d":"4.26E-05"}]
["CTBS","black",0.516520425039171,{"v":6.00104371239153e-12,"d":"6.00E-12"}]
["CTNNB1","black",0.402255732818205,{"v":2.12137598755504e-07,"d":"2.12E-07"}]
["CTR9","black",0.570708685263832,{"v":8.98880247424424e-15,"d":"8.99E-15"}]
["CXorf21","black",0.386569464082749,{"v":6.75356777126226e-07,"d":"6.75E-07"}]
["CXorf23","black",0.570284077990975,{"v":9.50331951814885e-15,"d":"9.50E-15"}]
["CYB5R4","black",0.722624851584018,{"v":2.57454711832938e-26,"d":"2.57E-26"}]
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["SPOPL","black",0.677817473525807,{"v":3.44593439540059e-22,"d":"3.45E-22"}]
["SPRYD3","black",0.0589909261181362,0.465927361628133]
["SRPK1","black",0.19744048393067,0.0137969306301208]
["SSTR2","black",0.286575478729464,0.000300254675441647]
["ST6GALNAC3","black",0.355619384518846,{"v":5.60085969693681e-06,"d":"5.60E-06"}]
["STK17B","black",0.571473757765976,{"v":8.12938145981059e-15,"d":"8.13E-15"}]
["STOML2","black",-0.402555965821547,{"v":2.07365749623904E-7,"d":"2.07E-07"}]
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["SULF2","black",0.239684650509545,0.00266625128456457]
["SYAP1","black",0.144948991115717,0.0719382654479458]
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["TDP2","black",0.635873059917569,{"v":6.15408505975668e-19,"d":"6.15E-19"}]
["TGFA","black",0.441944405955421,{"v":8.57105938087783e-09,"d":"8.57E-09"}]
["TLR1","black",0.589735730657342,{"v":6.82104922437393e-16,"d":"6.82E-16"}]
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["TMSB4X","black",0.452851214968071,{"v":3.2934526873909e-09,"d":"3.29E-09"}]
["TMX4","black",0.231458324917252,0.00375833814597466]
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["TNFSF14","black",0.0840131345403568,0.298652585636288]
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["TOPORS","black",0.639193708598626,{"v":3.54789449154444e-19,"d":"3.55E-19"}]
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["TPST1","black",0.179201669573626,0.0256761170638553]
["TRIB1","black",0.169536750820416,0.0349513613542088]
["TSEN34","black",-0.0246293551409271,0.760977747692354]
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["TUBA4A","black",0.214638284920482,0.00731996681861795]
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["USP8","black",0.629277036853414,{"v":1.80204842730064E-18,"d":"1.80E-18"}]
["VNN3","black",0.233838130828165,0.00340703515829835]
["VPS26A","black",0.392231262231131,{"v":4.47710336405132e-07,"d":"4.48E-07"}]
["WDR46","black",-0.410026103279884,{"v":1.1688180024346E-7,"d":"1.17E-07"}]
["WRB","black",0.617139833318173,{"v":1.21848988468932E-17,"d":"1.22E-17"}]
["WSB1","black",0.355519353028125,{"v":5.63731046139033e-06,"d":"5.64E-06"}]
["WSB2","black",0.411487894750006,{"v":1.04305910216759E-7,"d":"1.04E-07"}]
["XRN2","black",0.437534963878721,{"v":1.24985775254256e-08,"d":"1.25E-08"}]
["YIPF4","black",0.575627793203271,{"v":4.68924474260341e-15,"d":"4.69E-15"}]
["YTHDF3","black",0.820958029768524,{"v":4.54160793250254e-39,"d":"4.54E-39"}]
["YY1","black",0.494514346741672,{"v":6.15774216881494E-11,"d":"6.16E-11"}]
["ZFAND6","black",0.350785315777888,{"v":7.64385707889693e-06,"d":"7.64E-06"}]
["ZFP36L1","black",0.38914829290104,{"v":5.60566638683297e-07,"d":"5.61E-07"}]
["ZNF354A","black",0.423807076282122,{"v":3.91017185181611e-08,"d":"3.91E-08"}]
["ZNF652","black",0.369809872772128,{"v":2.18176901228766e-06,"d":"2.18E-06"}]

{"sheet":"Supplementary Table6","index":5,"n_rows":32,"n_cols":3,"rows_kept":32,"merged":[[0,0,0,2]]}
["Supplementary Table 6. The key genes identifed by the LASSO regres‑\nsion and/or SVM-RFE algorithm"]
["Names","total","elements"]
["LASSO SVM-RFE",7,"WDR46"]
[null,null,"ABCA1"]
[null,null,"ANTXR2"]
[null,null,"PRRG4"]
[null,null,"CPD"]
[null,null,"PLXDC2"]
[null,null,"C19orf24"]
["LASSO",17,"GGH"]
[null,null,"SAP30"]
[null,null,"ADH4"]
[null,null,"S100A12"]
[null,null,"DCTN4"]
[null,null,"ZFAND6"]
[null,null,"KDM3A"]
[null,null,"CCNG2"]
[null,null,"FAM102B"]
[null,null,"SENP7"]
[null,null,"ST6GALNAC3"]
[null,null,"HSDL2"]
[null,null,"TNFSF13B"]
[null,null,"ARRDC4"]
[null,null,"DOPEY2"]
[null,null,"WSB1"]
[null,null,"GNB4"]
["SVM-RFE",6,"SRPK1"]
[null,null,"NPL"]
[null,null,"TMX4"]
[null,null,"HECW2"]
[null,null,"SLC22A4"]
[null,null,"PJA2"]