ID	Description	GeneRatio	BgRatio	pvalue	p.adjust	qvalue	geneID	Count	one_type	two_type
hsa00830	Retinol metabolism	22/638	67/7914	5.17E-09	1.59E-06	1.41E-06	CYP2A6/AOX1/ADH4/CYP2B6/ADH1A/ADH1C/UGT1A8/ADH1B/UGT1A5/RDH8/CYP3A4/CYP2C9/UGT1A7/HSD17B6/CYP1A2/CYP1A1/CYP4A11/CYP2C8/CYP3A5/CYP26B1/CYP4A22/UGT1A10	22	Metabolism	Metabolism of cofactors and vitamins
hsa05204	Chemical carcinogenesis	22/638	82/7914	3.04E-07	3.36E-05	2.99E-05	CYP2A6/CYP2E1/NAT2/CYP2A13/ALDH3B2/GSTM1/CHRNA7/ADH4/ADH1A/ADH1C/UGT1A8/ADH1B/UGT1A5/CYP3A4/CYP2C9/CYP3A43/UGT1A7/CYP1A2/CYP1A1/CYP2C8/CYP3A5/UGT1A10	22	Human Diseases	Cancer: overview
hsa00980	Metabolism of xenobiotics by cytochrome P450	21/638	76/7914	3.29E-07	3.36E-05	2.99E-05	CYP2A6/CYP2E1/CYP2A13/ALDH3B2/GSTM1/AKR7A3/ADH4/CYP2B6/ADH1A/ADH1C/UGT1A8/ADH1B/UGT1A5/CYP3A4/CYP2C9/UGT1A7/CYP1A2/DHDH/CYP1A1/CYP3A5/UGT1A10	21	Metabolism	Xenobiotics biodegradation and metabolism
hsa00982	Drug metabolism - cytochrome P450	20/638	72/7914	5.71E-07	4.38E-05	3.89E-05	CYP2A6/CYP2E1/ALDH3B2/GSTM1/AOX1/ADH4/CYP2B6/ADH1A/ADH1C/UGT1A8/ADH1B/UGT1A5/FMO3/CYP3A4/CYP2C9/UGT1A7/CYP1A2/CYP2C8/CYP3A5/UGT1A10	20	Metabolism	Xenobiotics biodegradation and metabolism
hsa04110	Cell cycle	26/638	124/7914	4.53E-06	0.000278121	0.000246985	SMC1B/SFN/GADD45G/CCNE1/CDKN2A/CDC7/CDC25C/CCNA2/PTTG1/CCNB2/CDK1/CDC6/MCM2/CDC25A/CCNB1/TTK/ORC1/BUB1/E2F2/BUB1B/PLK1/CDC45/MAD2L1/CDC20/PKMYT1/ORC6	26	Cellular Processes	Cell growth and death
hsa04978	Mineral absorption	16/638	58/7914	8.53E-06	0.000384268	0.00034125	SLC5A1/SLC6A19/TRPV6/ATP1A4/SLC26A9/MT1F/MT1E/MT1H/TRPM6/MT1M/MT1A/SLC34A3/MT2A/MT1G/SLC34A2/MT1X	16	Organismal Systems	Digestive system
hsa04080	Neuroactive ligand-receptor interaction	51/638	340/7914	8.76E-06	0.000384268	0.00034125	CHRND/GABRG3/GLP1R/CHRNA4/NPFFR2/GABRB3/PRSS2/GRM4/GABRR3/HTR1D/NTS/GCGR/GRPR/LPAR1/GNRH2/P2RX2/CTSG/GRIN1/LPAR3/KISS1R/GRM1/SSTR2/LHB/INSL3/CHRNA1/CHRNA7/NMU/ADORA1/P2RY4/GABRQ/GABBR2/TAC3/ADRA1A/HRH2/GABBR1/RXFP4/HTR2B/VIPR1/DRD1/P2RX6/OXTR/ADORA2B/GHR/SSTR3/SCTR/CNR1/P2RY6/GRIK2/LPAR2/CALCR/GIPR	51	Environmental Information Processing	Signaling molecules and interaction
hsa04976	Bile secretion	17/638	72/7914	4.18E-05	0.001603491	0.001423982	SLC5A1/CFTR/ADCY8/AQP8/SLCO1B7/ADCY1/ATP1A4/SLCO1B3/AQP9/SLC10A1/SLC22A1/CYP3A4/ABCB4/SCTR/SLC27A5/SLC2A1/NCEH1	17	Organismal Systems	Digestive system
hsa04512	ECM-receptor interaction	18/638	88/7914	0.000184168	0.006282187	0.005578901	TNR/COL2A1/COL4A6/IBSP/FRAS1/COMP/TNC/SPP1/SV2A/FREM1/ITGB6/ITGB8/LAMA1/HMMR/ITGB4/COL9A2/ITGA3/LAMC2	18	Environmental Information Processing	Signaling molecules and interaction
hsa03320	PPAR signaling pathway	16/638	76/7914	0.000293748	0.009018078	0.008008511	RXRG/OLR1/FABP4/CYP8B1/ACSL6/APOA5/FABP3/HMGCS2/CYP4A11/SLC27A5/APOC3/FABP5/CYP4A22/PLTP/MMP1/FABP6	16	Organismal Systems	Endocrine system
hsa04114	Oocyte meiosis	22/638	127/7914	0.000462977	0.012921274	0.011474747	ADCY8/ADCY1/SMC1B/CAMK2B/AR/IGF1R/CPEB1/CCNE1/FBXO43/CPEB3/ITPR3/CDC25C/PTTG1/CCNB2/CDK1/CCNB1/SGO1/BUB1/PLK1/MAD2L1/CDC20/PKMYT1	22	Cellular Processes	Cell growth and death
hsa04727	GABAergic synapse	17/638	89/7914	0.000640342	0.016382078	0.014548116	GABRG3/ADCY8/GABRB3/GABRR3/ADCY1/GAD1/SLC12A5/GABRQ/GABBR2/HAP1/GABBR1/SLC38A1/SLC6A12/SLC38A5/SLC6A13/PRKCG/GNB3	17	Organismal Systems	Nervous system
hsa00140	Steroid hormone biosynthesis	13/638	60/7914	0.000800985	0.018915559	0.016797976	CYP2E1/AKR1D1/SRD5A2/UGT1A8/UGT1A5/CYP3A4/UGT1A7/HSD17B6/CYP1A2/CYP1A1/CYP19A1/CYP3A5/UGT1A10	13	Metabolism	Lipid metabolism
hsa00565	Ether lipid metabolism	11/638	47/7914	0.001017161	0.022304894	0.019807877	PLA2G2A/ENPP6/PLPP2/PLA2G2D/GAL3ST1/PAFAH1B3/GDPD3/LPCAT1/PLA2G7/LPCAT4/UGT8	11	Metabolism	Lipid metabolism
hsa04974	Protein digestion and absorption	17/638	95/7914	0.001374802	0.027688654	0.02458893	PRSS2/COL2A1/SLC6A19/CPA1/COL22A1/ACE2/ATP1A4/COL10A1/MEP1A/COL4A6/SLC36A2/COL11A2/COL28A1/COL11A1/COL24A1/COL9A2/SLC1A5	17	Organismal Systems	Digestive system
hsa01100	Metabolic pathways	145/638	1439/7914	0.001443057	0.027688654	0.02458893	COX7B2/GALNTL6/PLA2G2A/ADCY8/NQO1/CA4/CYP2A6/CYP2E1/CERS1/PLPP2/B4GALNT4/GUCY2C/NAT2/ADCY1/HAO2/SDS/B3GALT1/PLA2G2D/NNMT/CKMT1A/AKR1D1/PTGDS/ALDH3B2/PYCR1/CKMT1B/GAL3ST1/GSTM1/UROC1/GAD1/OAT/DGKK/AK5/ELOVL7/HPSE2/GGT6/TAT/GNMT/ENTPD3/HDC/GPLD1/RIMKLA/COX6B2/GYS2/AOX1/GALNT3/CYP4F2/ADH4/CYP8B1/CYP2B6/GLYAT/CNDP1/ADH1A/ATP6V0D2/NMNAT2/OLAH/ADH1C/DAO/ACSL6/UGT1A8/INPP5J/ETNPPL/ADH1B/ASAH2/CA14/PDE11A/UGT1A5/ALDOB/ELOVL4/CHIT1/KMO/ALOX5/RDH8/FBP1/PDE6A/AANAT/ASRGL1/MGAM2/CYP3A4/CYP2C9/NOS2/DMGDH/HAO1/CTH/UGT1A7/HSD17B6/CYP1A2/TPH1/TKFC/DHDH/MBOAT2/ASPDH/HACD1/GCNT1/NDUFA4L2/GPAT2/CYP1A1/HMGCS2/PIP5KL1/B3GALT5/CHAC1/PFKFB3/GALNT5/CYP4A11/CYP19A1/CYP2C8/G6PC/PAFAH1B3/SLC27A5/AKR1B1/LPCAT1/ACER1/MTHFD1/ELOVL3/PDE2A/CYP3A5/CYP26B1/GALNT15/CYP4A22/PLCD3/SPHK1/UGT1A10/ALAS1/EPHX2/FUT3/B3GALT2/TUSC3/PLA2G7/PFKP/RRM2/TK1/ALDOA/UAP1L1/IMPDH1/ALDH2/ST6GALNAC5/BCAT1/CA9/IL4I1/LPCAT4/GCNT3/ENO2/UGT8/TKTL1/PKM/G6PD	145	Metabolism	Global and overview maps
hsa00010	Glycolysis / Gluconeogenesis	13/638	68/7914	0.002676206	0.048329124	0.042918715	ALDH3B2/ADH4/ADH1A/ADH1C/ADH1B/ALDOB/FBP1/G6PC/PFKP/ALDOA/ALDH2/ENO2/PKM	13	Metabolism	Carbohydrate metabolism
hsa00051	Fructose and mannose metabolism	8/638	33/7914	0.003872542	0.064209049	0.057020894	ALDOB/FBP1/TKFC/PFKFB3/AKR1B1/PFKFB4/PFKP/ALDOA	8	Metabolism	Carbohydrate metabolism
hsa00590	Arachidonic acid metabolism	12/638	63/7914	0.00397385	0.064209049	0.057020894	PLA2G2A/CYP2E1/PLA2G2D/PTGDS/CYP4F2/CYP2B6/ALOX5/CYP2C9/CYP4A11/CYP2C8/CYP4A22/EPHX2	12	Metabolism	Lipid metabolism
hsa04929	GnRH secretion New!	12/638	64/7914	0.004542374	0.067375007	0.059832425	CACNA1G/GNRH2/KISS1R/LHB/KCNN1/CACNA1I/GABBR2/GABBR1/SPP1/PRKCG/TRPC1/ITPR3	12	Organismal Systems	Endocrine system
hsa00232	Caffeine metabolism	3/638	5/7914	0.004608714	0.067375007	0.059832425	CYP2A6/NAT2/CYP1A2	3	Metabolism	Biosynthesis of other secondary metabolites
hsa04971	Gastric acid secretion	13/638	75/7914	0.006420366	0.089007644	0.079043305	CFTR/ADCY8/ADCY1/ATP1A4/KCNJ10/KCNJ16/CAMK2B/SSTR2/HRH2/PRKCG/MYLK2/ITPR3/KCNE2	13	Organismal Systems	Digestive system
hsa00350	Tyrosine metabolism	8/638	36/7914	0.006811342	0.089007644	0.079043305	ALDH3B2/TAT/AOX1/ADH4/ADH1A/ADH1C/ADH1B/IL4I1	8	Metabolism	Amino acid metabolism
hsa00591	Linoleic acid metabolism	7/638	29/7914	0.006958252	0.089007644	0.079043305	PLA2G2A/CYP2E1/PLA2G2D/CYP3A4/CYP2C9/CYP1A2/CYP2C8	7	Metabolism	Lipid metabolism
hsa04911	Insulin secretion	14/638	86/7914	0.0083983	0.103131119	0.091585667	KCNU1/GLP1R/ADCY8/ADCY1/ATP1A4/RIMS2/KCNMB2/CAMK2B/SNAP25/KCNN1/PCLO/PRKCG/ITPR3/SLC2A1	14	Organismal Systems	Endocrine system
hsa04914	Progesterone-mediated oocyte maturation	15/638	98/7914	0.011404165	0.134656867	0.119582131	ADCY8/ADCY1/IGF1R/CPEB1/CPEB3/CDC25C/CCNA2/CCNB2/CDK1/CDC25A/CCNB1/BUB1/PLK1/MAD2L1/PKMYT1	15	Organismal Systems	Endocrine system
hsa04020	Calcium signaling pathway	25/638	193/7914	0.011900223	0.135309947	0.1201621	ERBB4/ADCY8/ADCY1/CACNA1G/GRPR/P2RX2/GRIN1/GRM1/CAMK2B/CHRNA7/CACNA1I/ADRA1A/HRH2/NOS2/HTR2B/PRKCG/DRD1/P2RX6/OXTR/ADORA2B/GNA14/MYLK2/PLCD3/SPHK1/ITPR3	25	Environmental Information Processing	Signal transduction
hsa05032	Morphine addiction	14/638	91/7914	0.013638234	0.149533498	0.132793335	GABRG3/ADCY8/GABRB3/GABRR3/ADCY1/ADORA1/GABRQ/PDE11A/GABBR2/GABBR1/PRKCG/DRD1/GNB3/PDE2A	14	Human Diseases	Substance dependence
hsa04918	Thyroid hormone synthesis	12/638	74/7914	0.014536661	0.151956718	0.134945277	ADCY8/LRP2/ADCY1/ATP1A4/DUOXA2/SERPINA7/TTR/TG/DUOX2/PRKCG/ASGR2/ITPR3	12	Organismal Systems	Endocrine system
hsa04742	Taste transduction	13/638	83/7914	0.014849191	0.151956718	0.134945277	ADCY8/GRM4/HTR1D/TRPM5/P2RX2/GRM1/P2RY4/GABBR2/HCN4/GABBR1/GNB3/HTR3A/ITPR3	13	Organismal Systems	Sensory system
hsa05146	Amoebiasis	15/638	102/7914	0.016167142	0.160106862	0.142183018	ADCY1/CTSG/CXCL3/COL4A6/CXCL8/CXCL1/NOS2/IL12A/PRKCG/C8A/GNA14/LAMA1/CD1A/ITGAM/LAMC2	15	Human Diseases	Infectious disease: parasitic
hsa00380	Tryptophan metabolism	8/638	42/7914	0.017347043	0.166423197	0.147792244	AOX1/KMO/AANAT/CYP1A2/TPH1/CYP1A1/ALDH2/IL4I1	8	Metabolism	Amino acid metabolism
hsa00071	Fatty acid degradation	8/638	44/7914	0.02261583	0.210395751	0.186842104	ADH4/ADH1A/ADH1C/ACSL6/ADH1B/CYP4A11/CYP4A22/ALDH2	8	Metabolism	Lipid metabolism
hsa00983	Drug metabolism - other enzymes	12/638	79/7914	0.023530504	0.212466614	0.188681135	CYP2A6/CYP2E1/NAT2/GSTM1/UGT1A8/UGT1A5/CYP3A4/UGT1A7/UGT1A10/RRM2/TK1/IMPDH1	12	Metabolism	Xenobiotics biodegradation and metabolism