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\begin{document}
\begin{appendices}
\section{Biomarker Levels}
\begin{table}[h!]
\centering 
\caption{Cut-off values to indicate normal/adequate ranges for nutritional biomarkers.}
    \begin{tabular}{l l}
    \hline
    \textbf{Biomarker} & \textbf{Cut-Off Value} \\
    \hline
 \textit{B-Vitamins}  &  \\
    \quad   Serum folate\footnotemark[1]  & $>$ 10 nmol/L \\
       \quad Red blood cell folate\footnotemark[2] \\
    \quad Plasma pyridoxal-5-phosphate (vitamin B6)\footnotemark[3]   & $>$ 30 nmol/L  \\
    \quad  EGRac (riboflavin)\footnotemark[4] &  $<$ 1.40 \\
      \textit{Vitamin B12 biomarkers}  &   \\
   \quad  Serum total vitamin B12\footnotemark[5]   &   $>$ 221 pmol/L\\
   \quad   Serum holotranscobalamin\footnotemark[6] & $>$ 40 pmol/L  \\
   \quad Serum methylmalonic acid\footnotemark[7]&   $<$  0.27 $\mu$mol/L \\
     \textit{Other}   &   \\
   \quad   Serum total homocysteine\footnotemark[8]  &   $<$  16 $\mu$mol/L \\
   \quad   Serum 25(OH)D (vitamin D)\footnotemark[9]  &  $>$ 50 nmol/L \\
\hline
    \end{tabular}
    \footnotetext[1]{Selhub et al 2008 Food Nutr Bull 29(2, Suppl); S67–73.}
    \footnotetext[2]{See 1.}
    \footnotetext[3]{Bates et al 1999 Clin Chim Acta, 280(1-2); 101-11.}
    \footnotetext[4]{Jungert et al 2020 J Nutr 150(10); 2699–706.}
    \footnotetext[5]{Green et al 2017 Nat Rev Dis Primers 3(1); 17040.}
    \footnotetext[6]{Allen et al 2018 J Nutr 148; 995S-2027S.}
    \footnotetext[7]{See 5.}
    \footnotetext[8]{Refsum et al 2004 Clin Chem 50(1); 3–32.}
    \footnotetext[9]{Holick et al 2011 J Clin Endocrinol Metab 96(7); 1911-30.}
\end{table}




\begin{table}[h!]
\centering 
\caption{Normal ranges for ‘hospital-measured’ biomarkers (routine clinical bloods). All ranges were obtained from standard lab blood specimen request/result forms.}
    \begin{tabular}{l l}
    \hline
    \textbf{Biomarker} & \textbf{Cut-Off Value} \\
    \hline
 \quad   C-reactive protein (CRP) & 0.1 – 5.0 mg/L  \\
  \textit{Full Blood Profile}   &    \\
 \quad   White cell count (WCC)  & 4 – 11 109/L   \\
\quad    Haemoglobin (Hb)  &   130 – 180 g/L \\
 \quad    Mean corpuscular volume (MCV) &   96 – 100 fL \\
 \quad   Platelet count (PLT)  &  150 – 450 109/L  \\
 \quad   Hematocrit (HCT)  &   0.4 – 0.54 \\
   \textit{Liver and Kidney Function Tests} &    \\
\quad   Albumin   & 35 – 50 g/L   \\
\quad   Gamma GT   & 10 – 50 U/L   \\
\quad   Urea   &   2.5 – 7.8 mmol/L \\
\quad   Creatinine   &  59 – 104 $\mu$mol/L  \\
\quad   Alkaline phosphatase (AlkPhos)   & 30 – 130 U/L   \\
\quad   Glomerular filtration rate (GFR)   & $\geq$ 60 ml/min/1.73m2   \\
\textit{Electrolyte Profile}    &    \\
\quad  Sodium (Na)    &   133 – 146 mmol/L \\
 \quad    Potassium (K)  & 3.5 – 5.3 mmol/L  \\
  \textit{Bone Profile}   &   \\
 \quad   Calcium (Ca)   & 2.2 – 2.6 mmol/L  \\
 \quad   Phosphate (Po3)   &  0.8 – 1.5 mmol/L \\
 \quad   Parathyroid hormone (PTH)   & 14 – 65 pg/ml  \\
 \textit{Lipid Profile}    &   \\
 \quad   Cholesterol   &  2.8 – 5.0 mmol/L \\
 \quad    Low-density lipoprotein (LDL)  &1.0 – 3.0 mmol/L   \\
  \quad   High-density lipoprotein (HDL)  &  1.0 – 2.5 mmol/L \\
 \quad    Triglycerides  &  0.40 – 1.70 mmol/L \\
 \textit{Blood Glucose}    &   \\
  \quad    Glucose &  3.9 – 6.4 mmol/L \\
  \quad   Glycated haemoglobin (HbA1c)  &  $leq$ 6.5\% \\
\hline
    \end{tabular}
\end{table}










\section{Covariate Features}
\begin{table}[h!]
      \centering
            \small
     \caption{The features contained in the mental health view.}
    \begin{tabular}{|p{2cm}p{5cm}p{4cm}|}
    \hline
\textbf{Group}&\textbf{Name} & \textbf{Type} \\
\hline
 CES-D&Bothered by things  & Ordinal (4 levels)\\ 
     &Felt depressed &Ordinal (4 levels)\\ 
     &Felt the blues & Ordinal (4 levels)\\
     & Everything is an effort  & Ordinal (4 levels)\\
   &Hopeful about future & Ordinal (4 levels)\\
   & Worse than others &Ordinal (4 levels)\\
   &Trouble concentrating &  Ordinal (4 levels) \\
   &Happy &Ordinal (4 levels)\\
   & Felt life a failure& Ordinal (4 levels)  \\
   &Talk less than usual & Ordinal (4 levels)\\
  &Felt fearful& Ordinal (4 levels) \\ 
  &  Felt lonely &Ordinal (4 levels)\\
  &People are unfriendly&  Ordinal (4 levels) \\
   &Enjoyed life &Ordinal (4 levels) \\ 
   &Crying spells& Ordinal (4 levels)   \\
   &Couldn't get going &Ordinal (4 levels) \\
  & People dislike me&Ordinal (4 levels)   \\
  \hdashline
 HADS   &Feel something awful coming & Ordinal (4 levels)\\
 &Butterflies in stomach  &Ordinal (4 levels)\\
 &Tense and wound up & Ordinal (4 levels) \\
 &Restless on the move & Ordinal (4 levels) \\
    &Unable to sit at ease & Ordinal (4 levels)\\
 &Sudden feeling of panic  & Ordinal (4 levels)\\
 &Worrying thoughts &   Ordinal (4 levels) \\
     \hline
   \end{tabular}
\end{table}

\begin{table}[h!]
        \centering
            \small
       \caption{The features contained in the cognitive health view.}
    \begin{tabular}{|p{2cm}p{5cm}p{4cm}|}
    \hline
    \textbf{Group}&\textbf{Name} & \textbf{Type} \\
     \hline
  RBANS   &Semantic fluency &Continuous \\ 
     &Figure copying &Continuous\\ 
     &List learning &Continuous\\
      &Coding &Continuous\\ 
     &Picture naming  &Continuous\\ 
     &Story memory  & Continuous\\
    &List recall &Continuous\\ 
     &List recognition  &Continuous\\ 
     &Line orientation &Continuous\\
     & Figure recall& Continuous\\ 
     & Digit span &Continuous\\
     & Story recall& Continuous\\
 \hdashline
 FAB&Prehension behaviour  & Ordinal (4 levels)\\
&Similarities conceptualisation& Ordinal (4 levels)\\
  & Lexical fluency&Ordinal (4 levels) \\
  & Motor series programming& Ordinal (4 levels)\\
  & Sensitivity to interference& Ordinal (4 levels)\\
  & Inhibitory control& Ordinal (4 levels)\\
     \hdashline
 MMSE 1&Repeat phrase & Binary \\
  &Copy the design & Binary\\
  &Close your eyes & Binary\\
  &Write a sentence &Binary \\
\hdashline
 MMSE 2& Name three common objects& Ordinal (4 levels)\\
 & Follow three-stage command &Ordinal (4 levels) \\
 & Recall three objects & Ordinal (4 levels)\\
\hdashline
MMSE 3 & Year/Season/Date& Ordinal (6 levels)\\
  & Where are we &Ordinal (6 levels)\\
  & Serial sevens& Ordinal (6 levels)\\
  & Spell WORLD backwards&Ordinal (6 levels)\\
     \hline
   \end{tabular}
\end{table}

\begin{table}[h!]
        \centering
          \small
         \caption{The features contained in the illness and medications view. }
    \begin{tabular}{|p{2cm}p{5cm}p{4cm}|}
    \hline
    \textbf{Group}&\textbf{Name} & \textbf{Type} \\
     \hline
 Diagnoses  & Hypertension &Binary \\
  & Heart attack &Binary \\
  &Diabetes & Binary \\
  & Hyperlipidaemia &  Binary\\
  &Stroke &Binary \\
  &Ischaemic heart disease &Binary \\
   &  TIA &Binary \\
  &Angina & Binary\\
    &Peripheral artery disease  & Binary\\
  &Atrial fibrillation &Binary \\
    & ABI/Carotidartery doppler & Binary \\
  &Other serious disease&Binary \\
     &Carotid endarterectomy  & Binary\\
  &Osteoporosis & Binary\\
     & Bypass operation &Binary \\
  &Atrophic gastritis &Binary \\
     &Rheumatoid arthritis  & Binary\\
  &GI disease &Binary \\
     & Epilepsy & Binary\\
\hdashline
Medications   &Statins medications  &Binary \\
  &Anxiety medications  & Binary\\
  &Antipsychotic medications  &Binary\\
   & Lipid medications & Binary\\
  &Antidepressant medications  & Binary\\
  &Dementia medications &Binary \\
   &Vitamin D supplements  & Binary\\
     \hline
   \end{tabular}
   \end{table}



\begin{table}[h!]
        \centering
            \small
       \caption{The features contained in the lifestyle and nutrition view. }
    \begin{tabular}{|p{3cm}p{5cm}p{4cm}|}
    \hline
    \textbf{Group}&\textbf{Name} & \textbf{Type} \\
     \hline
 Deprivation  &Deprivation quintiles  & Ordinal (5 levels) \\
      \hdashline
Living Status  &Living With & Binary\\
   &Marital status &Binary \\
     \hdashline
Smoke/Drink   & Smoking  & Binary\\
   & Drinking & Binary\\
     \hdashline
   & White cell count &Binary\\
   &Haemoglobin  &Binary\\
   &Cholesterol &Binary \\
   &Creatinine & Binary\\
   &Albumin  &Binary \\
   &Mean corpuscular volume &Binary\\
   &Hematocrit &Binary\\
   &Gamma GT & Binary \\
   & Sodium &Binary\\
   &Urea &Binary\\
   &Triglycerides  & Binary\\
   &Low-density lipoprotein & Binary \\
   & Potassium &Binary\\
   &Total homocysteine &Binary\\
   &Glomerular filtration rate  &Binary \\
   &High-density lipoprotein & Binary \\
   &Phosphate  &Binary\\
   &Serum holotranscobalamin &Binary\\
   &Vitamin D & Binary \\
   &Glucose &Binary \\
   & Alkaline phosphatase &Binary \\
   &Serum methylmalonic acid &Binary\\
   &Total serum B12 &Binary \\
   &Parathyroid hormone & Binary\\
   & Platelet count &Binary\\
   & C-reactive protein &Binary \\
   &Glycated haemoglobin  & Binary\\
   & Riboflavin &Binary \\
   & Serum folate & Binary \\
   & Red blood cell folate & Binary\\
   &Plasma pyridoxal-5-phosphate (vitamin B6)  &Binary\\
     \hline
   \end{tabular}
   \end{table}

\begin{table}[h!]
        \centering
        \small
           \caption{The features contained in the physical health view.}
    \begin{tabular}{|p{2cm}p{7cm}p{4cm}|}
    \hline
    \textbf{Group}&\textbf{Name} & \textbf{Type} \\
     \hline
   Female  & Female & Binary\\
  \hdashline
 Age & Age &Continuous\\
  \hdashline
TUG &  TUG & Continuous\\
  \hdashline
 BMI& BMI & Continuous \\
\hdashline
 PSMS  &Fallen in last year &Binary\\
   & Dizzy when standing &Binary\\
   & Trouble getting to the bathroom on time &Binary\\
      &Care taken when rising & Binary\\
   & Fainted in the past year&Binary \\
   &Dizzy when rising &Binary\\
   & Eat with help & Binary \\
   &Afraid of falling &Binary\\
   & Dress with help & Binary \\
   &Limit household activities &Binary\\
   & Take care of appearance &Binary \\
   &Limit outside activities &Binary\\
   & Get around the house without help &Binary \\
   & Get in and out of bed & Binary \\
   & Able to bathe &Binary \\
   & Visual impairments & Binary\\
\hdashline
  IADL &Get to places outside walking distance & Ordinal (4 levels)\\
   & Do own handyman work & Ordinal (4 levels)\\
   & Manage own money & Ordinal (4 levels)\\
      & Shop for groceries& Ordinal (4 levels) \\
      & Use the telephone &Ordinal (4 levels)\\
   &Prepare own meals &Ordinal (4 levels) \\
   &Take own medicine & Ordinal (4 levels) \\
    &Do own housework & Ordinal (4 levels) \\
   &Do own laundry & Ordinal (4 levels) \\
     \hline
   \end{tabular}
   \end{table}


\section{Block-cluster Parameters}

\begin{table}[h!]
        \centering
           \caption{Block-cluster parameters for the mental health features. Larger modes indicate a higher frequency of symptoms. }
    \begin{tabular}{|p{1.4cm}|c|p{1.4cm}p{1.4cm}p{1.4cm}p{1.4cm}|}
    \hline
    & &\textbf{CES-D} & & & \\
    & & $(\mu, \pi)$ & & & \\
    & &Col C1 &Col C2 &Col C3 &Col C4 \\
     \hline
   &$n$& 8&8 & 3& 1 \\
     \hline
   Row C1&152&(0, 0.45)  &(0, 0.88)  &(1, 0.56) &(1, 0.56)  \\
   Row C2&315&(0, 0.33)  &(0, 0.57)  &(1, 0.23) &(3, 0.12)  \\
   Row C3&1088&(0, 0.35)  &(0, 0.67)  &(1, 0.35) &(1, 0.33)  \\
   Row C4&602&(0, 0.89)  &(0, 0.90)  &(0, 0.77) &(0, 0.23)  \\
   Row C5&3029&(0, 0.90)  &(0, 0.91)  &(0, 0.88) &(0, 0.57)   \\
     \hline
   \end{tabular}
    \begin{tabular}{|p{1.4cm}|c|p{1.4cm}p{1.4cm}p{1.4cm}p{1.4cm}|}
    \hline
    & &\textbf{HADS} & & & \\
    & & $(\mu, \pi)$ & & & \\
    & &Col C1 &Col C2 &Col C3 &Col C4 \\
     \hline
   &$n$& 2&2 & 2& 1 \\
     \hline
   Row C1&2495&(0, 0.91)  &(0, 0.92)  &(0, 0.78) &(0, 0.92)   \\
   Row C2&1134& (0, 0.23)  &(0, 0.44)  &(1, 0.34) &(1, 0.12)  \\
   Row C3&1557&(0, 0.45)  &(0, 0.66)  &(1, 0.34) &(0, 0.56)  \\
   Row C4&1557&(0, 0.45)  &(0, 0.56)  &(1, 0.57) &(1, 0.34)   \\
   Row C5&1557&(0, 0.88)  &(0, 0.89)  &(0, 0.67) &(0, 0.77)  \\
     \hline
   \end{tabular}
\end{table}

\begin{table}[h!]
        \centering
           \caption{Block-cluster parameters for the cognitive health features. }
    \begin{tabular}{|p{1.4cm}|c|p{1.8cm}p{1.8cm}p{1.8cm}:p{1.4cm}p{1.4cm}|}
    \hline
    & &\textbf{RBANS} & & &\textbf{FAB} &\\
    & & $(\mu, \sigma)$ & & &$(\mu, \pi)$ &\\
    & &Col C1 &Col C2 &Col C3 &Col C1 & Col C2  \\
     \hline
   &$n$& 4&3 & 5& 1 &5 \\
     \hline
   Row C1&1693&(0.66, 0.17)  &(0.16, 0.12)  &(0.43, 0.17) &(3, 0.92) &(3, 0.56) \\
   Row C2&1234&(0.81, 0.14) &(0.27, 0.20)  &(0.57, 0.18)  &(3, 0.92)  &(2, 0.23) \\
   Row C3&2259&(0.49, 0.17) &(0.08, 0.07)  &(0.28, 0.16)  &(3, 0.92) &(3, 0.78)   \\
     \hline
   \end{tabular}
    \begin{tabular}{|p{1.4cm}|c|p{1.4cm}p{1.4cm}p{1.4cm}p{1.4cm}p{1.4cm}p{1.4cm}|}
    \hline
    & &\textbf{MMSE} & & & & & \\
    & & $(\bm{p})$ & &$(\mu, \pi)$ & & &$(\mu, \pi)$ \\
    & &Col C1 &Col C2 &Col C1 &Col C2 &Col C3 & Col C1\\
     \hline
   &$n$& 3&1 & 1& 1 & 1& 4 \\
     \hline
   Row C1&1693& 0.07 &  0.26&(1, 1.00) &(3, 0.89) &(1, 0.23) &(5, 0.67)  \\
   Row C2&1234& 0.14&  0.63&(1, 0.92) &(3, 0.78) &(1, 0.34) &(5, 0.44)  \\
   Row C3&2259& 0.02&  0.07&(1, 1.00) &(3, 0.91) &(2, 0.34) &(5, 0.79)  \\
     \hline
   \end{tabular}
\end{table}


\begin{table}[h!]
        \centering
                   \caption{Block-cluster parameters for the illness and medications features. }
    \begin{tabular}{|p{1.4cm}|c|p{1.4cm}p{1.4cm}p{1.4cm}:p{1.4cm}p{1.4cm}p{1.4cm}|}
    \hline
    & &\textbf{Diagnoses} & & &\textbf{Medications} & &  \\
    & & $(\bm{p})$ & & &$(\bm{p})$ & & \\
    & &Col C1 &Col C2 &Col C3 &Col C1 &Col C2 &Col C3 \\
     \hline
   &$n$& 2&9 & 8& 3 &2 & 2\\
     \hline
   Row C1&1905&  0.60&  0.09& 0.23& 0.54 & 0.27& 0.08\\
   Row C2&3281& 0.65&  0.04&  0.16&  0.51& 0.10& 0.01 \\
     \hline
   \end{tabular}
\end{table}

\begin{table}[h!]
        \centering
           \caption{Block-cluster parameters for the lifestyle and nutrition features. }
    \begin{tabular}{|p{1.4cm}|c|p{2cm}:p{1.4cm}p{1.4cm}:p{2.3cm}|}
    \hline
    & &\textbf{Deprivation} &\textbf{Living/Marital} & &\textbf{Drink/Smoke} \\
    & & $(\mu, \pi)$ &$(\bm{p})$ & &$(\bm{p})$ \\
    & &Col C1 &Col C1 &Col C2 &Col C1 \\
     \hline
   &$n$& 1&1 & 1& 2 \\
     \hline
   Row C1&3281&(1, 0.01)  &  0.72& 0.63& 0.38 \\
   Row C2&1905&(5, 0.23) &  0.57&  0.35& 0.29  \\
     \hline
   \end{tabular}
    \begin{tabular}{|p{1.4cm}|c|p{1.4cm}p{1.4cm}p{1.4cm}p{1.4cm}|}
    \hline
    & &\textbf{Nutrition} & & & \\
    & & $(\bm{p})$ & & & \\
    & &Col C1 &Col C2 &Col C3 &Col C4 \\
     \hline
   &$n$& 11&6 & 6& 9 \\
     \hline
   Row C1&3281&  0.94& 0.03 & 0.64&  0.79\\
   Row C2&1905& 0.91&  0.06&  0.55&  0.73\\
     \hline
   \end{tabular}
\end{table}



\begin{table}[h!]
        \centering
           \caption{Block-cluster parameters for the physical health features. }
    \begin{tabular}{|p{1.4cm}|c|p{1.4cm}:p{1.8cm}:p{1.8cm}:p{1.8cm}|}
    \hline
    & &\textbf{Female} &\textbf{Age}&\textbf{TUG}&\textbf{BMI}\\
    & & $(\bm{p})$ &$(\mu, \sigma)$ &$(\mu, \sigma)$ &$(\mu, \sigma)$ \\
    & &Col C1 &Col C1 &Col C1 &Col C1 \\
     \hline
   &$n$& 1&1 & 1& 1\\
     \hline
   Row C1&1905& 0.69& (79.7, 7.7)& (21.4, 11.0)& (27.5, 5.9) \\
   Row C2&3281& 0.66& (70.7, 6.6)& (9.9, 3.8)& (28.1, 5.0) \\
     \hline
   \end{tabular}
       \begin{tabular}{|p{1.4cm}|c|p{1.4cm}p{1.4cm}p{1.4cm}:p{1.4cm}p{1.4cm}p{1.4cm}|}
    \hline
    & &\textbf{IADL}  & & &\textbf{PSMS} & & \\
    & & $(\bm{p})$ & & & $(\mu, \pi)$ & &  \\
    & & Col C1 &Col C2 &Col C3 &Col C1 &Col C2 & Col C3\\
     \hline
   &$n$&6 &9  &1 &5 &1 &3 \\
     \hline
   Row C1&1905& 0.65&  0.17& 0.73&(1, 0.12) & (0, 0.79)&(2, 0.66)\\
   Row C2&3281&0.31 & 0.03 & 0.86& (2, 0.88)& (2, 0.23)&(2, 0.92)\\
     \hline
   \end{tabular}
\end{table}


\section{Feature Clusterings}

\begin{table}[h!]
        \centering
            \small
     \caption{Column-clusters for the cognitive health features.  }
    \begin{tabular}{|c|p{4.5cm}p{4.5cm}p{4.5cm}|}
    \hline
     &\textbf{RBANS} & & \\
     &Col C1 &Col C2 &Col C3 \\
     \hline
   $n$& 4&3 & 5 \\
     \hline
     &Semantic fluency & Figure copying &List learning \\
      &Coding &Picture naming  &Story memory \\
    &List recall &List recognition  &Line orientation \\
     & Figure recall&  &Digit span \\
     & &  &Story recall\\
 \hline
   \end{tabular}
       \begin{tabular}{|c|p{5cm}p{5cm}|}
    \hline
    &\textbf{FAB} &\\
    &Col C1 & Col C2  \\
     \hline
   $n$&1 &5 \\
     \hline
 &Prehension behaviour  & Similarities conceptualisation\\
  & & Lexical fluency\\
  & & Motor series programming\\
  & & Sensitivity to interference\\
  & & Inhibitory control\\
     \hline
   \end{tabular}
       \begin{tabular}{|c|p{5cm}p{5cm}|}
    \hline
    &\textbf{MMSE} &\\
    &Col C1 & Col C2  \\
     \hline
   $n$&1 &5 \\
     \hline
 &Repeat phrase & Copy the design\\
  &Close your eyes & \\
  &Write a sentence & \\
     \hline
   \end{tabular}
          \begin{tabular}{|c|p{3.5cm}p{3.5cm}p{3.5cm}:p{3.5cm}|}
    \hline
    &\textbf{MMSE} & & & \\
    &Col C1 & Col C2 & Col C3 & Col C1 \\
     \hline
   $n$&1& 1 & 1& 4  \\
     \hline
 & Name three common objects& Follow three stage command &Recall three objects & Year/Season/Date\\
  & &  & &Where are we \\
  & &  & &Serial sevens \\
  & &  & & Spell WORLD backwards\\
     \hline
   \end{tabular}
\end{table}



\begin{table}[h!]
        \centering
            \small
            \caption{Column-clusters for the illness and medication features.}

    \begin{tabular}{|c|p{4.5cm}p{4.5cm}p{4.5cm}|}
    \hline
     &\textbf{Diagnoses} & & \\
     &Col C1 &Col C2 &Col C3 \\
     \hline
   $n$& 2&9 & 8\\
     \hline
   & Hypertension & Heart attack &Diabetes \\
   & Hyperlipidaemia & Stroke &Ischaemic heart disease \\
   &  & TIA &Angina \\
   &  &Peripheral artery disease  &Atrial fibrilation \\
   &  & ABI/Carotidartery doppler & Other serious disease\\
   &  &Carotid endarterectomy  &Osteoporosis \\
   &  & Bypass operation &Atrophic gastritis \\
   &  &Rheumatoid arthritis  &GI disease \\
   &  & Epilepsy & \\
     \hline
   \end{tabular}
    \begin{tabular}{|c|p{4.5cm}p{4.5cm}p{4.5cm}|}
    \hline
    &\textbf{Medications} & &  \\
     &Col C1 &Col C2 &Col C3 \\
     \hline
   $n$ &3 &2 & 2\\
     \hline
   &Statins medications  &Anxiety medications  &Antipsychotic medications \\
   & Lipid medications &Antidepressant medications  &Dementia medications \\
   &Vitamin D supplements  &  & \\
     \hline
   \end{tabular}
   \end{table}


\begin{table}[h!]
        \centering
               \small
\caption{Column-clusters for the lifestyle and nutrition features.}
    \begin{tabular}{|c|p{3.5cm}:p{3.5cm}p{3.5cm}:p{3.5cm}|}
    \hline
    &\textbf{Deprivation} &\textbf{Living/Marital} & &\textbf{Drink/Smoke} \\
     &Col C1 &Col C1 &Col C2 &Col C1 \\
     \hline
   $n$& 1&1 & 1& 2 \\
     \hline
   &Deprivation quintiles  & Living With &Marital status & Smoking \\
   &  &  & & Drinking \\
     \hline
   \end{tabular}
    \begin{tabular}{|c|p{3.5cm}p{3.5cm}p{3.5cm}p{3.5cm}|}
    \hline
     &\textbf{Nutrition} & & & \\
     &Col C1 &Col C2 &Col C3 &Col C4 \\
     \hline
   $n$& 11&6 & 6& 9 \\
     \hline
   & White cell count &Haemoglobin  &Cholesterol & Creatinine \\
   &Albumin  & Mean corpuscular volume &Hematocrit &Gamma GT  \\
   & Sodium &Urea &Triglycerides  & Low-density lipoprotein  \\
   & Potassium &Total homocysteine &Glomerular filtration rate  & High-density lipoprotein  \\
   &Phosphate  & Serum holotranscobalamin &Vitamin D &  Glucose\\
   & Alkaline phosphatase & Serum methylmalonic acid &Total serum B12 & Parathyroid hormone \\
   & Platelet count &  & & C-reactive protein \\
   &Glycated haemoglobin  &  & & Riboflavin  \\
   & Serum folate &  & &  \\
   & Red blood cell folate &  & &  \\
   &Plasma pyridoxal-5-phosphate (vitamin B6)  &  & &  \\
     \hline
   \end{tabular}
\end{table}

\begin{table}[h!]
    \centering
    \small
 \caption{Column-clusters for the physical health features.}
\begin{tabular}{|c|p{3.5cm}:p{3.5cm}:p{3.5cm}:p{3.5cm}|}
    \hline
     &\textbf{Female} &\textbf{Age}&\textbf{TUG}&\textbf{BMI}\\
     &Col C1 &Col C1 &Col C1 &Col C1 \\
     \hline
$n$& 1&1 & 1& 1\\ 
     \hline
     & Female & Age & TUG & BMI \\
          \hline
   \end{tabular}
          \begin{tabular}{|c|p{4cm}p{4.5cm}p{5.5cm}|}
    \hline
     &\textbf{IADL}  & & \\
     & Col C1 &Col C2 &Col C3 \\
     \hline
   $n$&6 &9  &1 \\
     \hline
   &Fallen in last year &Dizzy when standing &Trouble getting to bathroom on time \\
      &Care taken when rising & Fainted in past year& \\
   &Dizzy when rising &Eat with help &  \\
   &Afraid of falling &Dress with help &  \\
   &Limit household activities &Take care of appearance & \\
   &Limit outside activities &Get around house without help & \\
   & &Get in and out of bed &  \\
   & &Able to bathe & \\
   & &Visual impairments & \\
     \hline
   \end{tabular}
          \begin{tabular}{|c|p{4cm}p{4.5cm}p{5.5cm}|}
    \hline
     &\textbf{PSMS} & & \\
     &Col C1 &Col C2 & Col C3\\
     \hline
   $n$ &5 &1 &3 \\
     \hline
   &Get to places outside walking distance &Do own handymanwork & Manage own money\\
      & Shop for groceries& & Use the telephone\\
   &Prepare own meals & &Take own medicine \\
    &Do own housework & & \\
   &Do own laundry & & \\
     \hline
   \end{tabular}
\end{table}

\end{appendices}

\end{document}
