{"text_format":"3","workbook":"xls","n_sheets":1,"sheets":["Additional file 12"],"not_rendered":{"macros":1},"read":"whole","date_system":"1900","formulas":"cached_only"}

{"sheet":"Additional file 12","index":0,"n_rows":258,"n_cols":19,"rows_kept":258,"merged":[[0,0,0,13]],"flags":["formulas_cached_only"]}
["Additional file 12: Abundance of the metagenomic microbial function profiling (KEGG  level 3 pathways).          \n"]
["ko","DHS3","DHSW","GS","LSY","MG","MLPY","NPPH","XC2","ZGS","Pathway ","Pathway name","level2","level1"]
["ko00010",111.5859,107.9534,104.5199,96.2673,133.3187,107.186,147.8345,100.9892,123.0621,"Glycolysis / Gluconeogenesis [PATH:ko00010]","Glycolysis / Gluconeogenesis ","Carbohydrate metabolism","Metabolism"]
["ko00020",143.5364,139.8632,142.2927,129.9191,182.3384,141.6662,220.6764,135.5738,163.47,"Citrate cycle (TCA cycle) [PATH:ko00020]","Citrate cycle (TCA cycle) ","Carbohydrate metabolism","Metabolism"]
["ko00030",90.6332,85.6767,79.23,71.7105,102.8549,81.9608,103.2706,78.7104,93.3998,"Pentose phosphate pathway [PATH:ko00030]","Pentose phosphate pathway ","Carbohydrate metabolism","Metabolism"]
["ko00040",29.8135,28.5292,27.4947,27.4457,30.4559,31.6929,35.0132,36.8111,32.387,"Pentose and glucuronate interconversions [PATH:ko00040]","Pentose and glucuronate interconversions ","Carbohydrate metabolism","Metabolism"]
["ko00051",35.864,34.8115,34.9166,32.7439,38.7983,37.6823,47.2516,37.8211,40.9775,"Fructose and mannose metabolism [PATH:ko00051]","Fructose and mannose metabolism ","Carbohydrate metabolism","Metabolism"]
["ko00052",45.541,43.9149,41.0584,39.6749,42.5495,45.7028,47.0561,52.4937,47.0801,"Galactose metabolism [PATH:ko00052]","Galactose metabolism ","Carbohydrate metabolism","Metabolism"]
["ko00053",36.3892,35.6058,39.6558,38.1777,42.2494,37.1517,51.4808,39.6721,47.2801,"Ascorbate and aldarate metabolism [PATH:ko00053]","Ascorbate and aldarate metabolism ","Carbohydrate metabolism","Metabolism",{"$nulls":4}," "]
["ko00061",121.2783,121.3829,135.8558,125.5189,152.0749,133.4238,181.1961,119.9712,156.831,"Fatty acid biosynthesis [PATH:ko00061]","Fatty acid biosynthesis ","Lipid metabolism","Metabolism"]
["ko00071",111.3418,113.5913,120.8092,120.1174,129.1041,115.5261,152.0883,103.0694,141.1175,"Fatty acid degradation [PATH:ko00071]","Fatty acid degradation ","Lipid metabolism","Metabolism"]
["ko00072",203.473,209.406,233.3622,229.6935,238.4337,219.065,290.193,190.9532,279.7842,"Synthesis and degradation of ketone bodies [PATH:ko00072]","Synthesis and degradation of ketone bodies ","Lipid metabolism","Metabolism"]
["ko00073",0.0376,0.0261,1.5424,2.3209,0.1024,0.1147,0,0.3634,0.5323,"Cutin, suberine and wax biosynthesis [PATH:ko00073]","Cutin, suberine and wax biosynthesis ","Lipid metabolism","Metabolism"]
["ko00100",0.8405,1.0131,1.4886,2.0059,1.8144,1.4273,1.884,1.8137,1.3654,"Steroid biosynthesis [PATH:ko00100]","Steroid biosynthesis ","Lipid metabolism","Metabolism"]
["ko00121",1.4672,1.5479,1.2019,1.6865,1.2271,1.2916,0.8778,1.3165,1.381,"Secondary bile acid biosynthesis [PATH:ko00121]","Secondary bile acid biosynthesis ","Lipid metabolism","Metabolism"]
["ko00130",35.7976,35.5567,37.9273,34.6017,42.9257,39.4314,51.5831,39.4908,44.5154,"Ubiquinone and other terpenoid-quinone biosynthesis [PATH:ko00130]","Ubiquinone and other terpenoid-quinone biosynthesis ","Metabolism of cofactors and vitamins","Metabolism"]
["ko00140",17.3452,16.9501,10.3587,8.5269,40.7658,7.8607,26.9841,6.4516,12.247,"Steroid hormone biosynthesis [PATH:ko00140]","Steroid hormone biosynthesis ","Lipid metabolism","Metabolism"]
["ko00190",49.0473,47.7058,52.222,49.7358,62.1209,48.4187,70.225,52.7606,57.221,"Oxidative phosphorylation [PATH:ko00190]","Oxidative phosphorylation ","Energy metabolism","Metabolism"]
["ko00195",25.2886,25.0557,44.4971,43.2083,34.9712,27.7222,39.3239,33.2382,37.9981,"Photosynthesis [PATH:ko00195]","Photosynthesis ","Energy metabolism","Metabolism"]
["ko00196",0.004,0,0.16,0.2175,0.0238,0.0194,0,0.0327,0.0523,"Photosynthesis - antenna proteins [PATH:ko00196]","Photosynthesis - antenna proteins ","Energy metabolism","Metabolism"]
["ko00220",70.4042,69.8034,75.7653,71.6782,86.8659,72.229,106.6976,68.4468,89.6031,"Arginine biosynthesis [PATH:ko00220]","Arginine biosynthesis ","Amino acid metabolism","Metabolism"]
["ko00230",55.9155,56.0771,62.1816,58.1062,69.3826,60.2133,85.8077,56.9976,70.9735,"Purine metabolism [PATH:ko00230]","Purine metabolism ","Nucleotide metabolism","Metabolism"]
["ko00240",67.5551,66.3827,75.2255,67.771,85.1472,74.014,105.4308,69.2997,86.8816,"Pyrimidine metabolism [PATH:ko00240]","Pyrimidine metabolism ","Nucleotide metabolism","Metabolism"]
["ko00250",120.9209,120.0709,126.6289,117.0771,150.4131,122.2306,182.8705,114.3051,148.9856,"Alanine, aspartate and glutamate metabolism [PATH:ko00250]","Alanine, aspartate and glutamate metabolism ","Amino acid metabolism","Metabolism"]
["ko00253",0.6762,0.9674,0,0,1.0853,0,1.1648,0,0,"Tetracycline biosynthesis [PATH:ko00253]","Tetracycline biosynthesis ","Metabolism of terpenoids and polyketides","Metabolism"]
["ko00260",90.7799,92.0199,94.1146,87.3087,108.0303,94.078,130.5847,89.5891,109.2334,"Glycine, serine and threonine metabolism [PATH:ko00260]","Glycine, serine and threonine metabolism ","Amino acid metabolism","Metabolism"]
["ko00261",72.0171,70.7019,77.8796,74.4943,89.4249,77.154,107.2136,77.2175,86.0174,"Monobactam biosynthesis [PATH:ko00261]","Monobactam biosynthesis ","Biosynthesis of other secondary metabolites","Metabolism"]
["ko00270",74.069,73.1916,77.8887,72.9225,95.7328,78.6085,110.899,78.2815,91.3079,"Cysteine and methionine metabolism [PATH:ko00270]","Cysteine and methionine metabolism ","Amino acid metabolism","Metabolism"]
["ko00280",127.6642,130.5257,136.7913,134.6003,144.4706,133.5522,178.2324,116.7501,161.879,"Valine, leucine and isoleucine degradation [PATH:ko00280]","Valine, leucine and isoleucine degradation ","Amino acid metabolism","Metabolism"]
["ko00281",71.5619,77.488,91.2886,90.8922,87.5555,85.6011,113.2951,75.607,106.3718,"Geraniol degradation [PATH:ko00281]","Geraniol degradation ","Metabolism of terpenoids and polyketides","Metabolism"]
["ko00290",245.9492,239.5031,247.3545,226.6896,320.5695,252.3862,346.2902,230.2929,283.5374,"Valine, leucine and isoleucine biosynthesis [PATH:ko00290]","Valine, leucine and isoleucine biosynthesis ","Amino acid metabolism","Metabolism"]
["ko00300",59.4422,60.4504,72.197,69.1502,77.8608,69.2633,97.114,65.3312,80.9155,"Lysine biosynthesis [PATH:ko00300]","Lysine biosynthesis ","Amino acid metabolism","Metabolism"]
["ko00310",56.1531,57.7624,60.8288,59.963,63.0039,58.8001,80.0374,52.4943,72.032,"Lysine degradation [PATH:ko00310]","Lysine degradation ","Amino acid metabolism","Metabolism"]
["ko00311",16.579,16.2509,20.16,18.4947,15.4712,19.6224,20.3971,20.8991,21.8701,"Penicillin and cephalosporin biosynthesis [PATH:ko00311]","Penicillin and cephalosporin biosynthesis ","Biosynthesis of other secondary metabolites","Metabolism"]
["ko00330",54.4232,53.9184,56.4358,52.2482,65.3166,53.9362,73.7254,50.5164,66.1352,"Arginine and proline metabolism [PATH:ko00330]","Arginine and proline metabolism ","Amino acid metabolism","Metabolism"]
["ko00332",12.4648,13.7719,16.6932,0,0,15.9391,21.6536,0,18.3072,"Carbapenem biosynthesis [PATH:ko00332]","Carbapenem biosynthesis ","Biosynthesis of other secondary metabolites","Metabolism"]
["ko00340",70.287,73.1085,80.4098,77.9392,80.0246,77.5212,102.6292,73.0101,92.1825,"Histidine metabolism [PATH:ko00340]","Histidine metabolism ","Amino acid metabolism","Metabolism"]
["ko00350",40.1484,40.2999,42.0082,43.6583,48.1461,40.3523,55.2818,43.7921,48.3543,"Tyrosine metabolism [PATH:ko00350]","Tyrosine metabolism ","Amino acid metabolism","Metabolism"]
["ko00360",52.4555,54.6122,61.1662,64.6857,60.8127,57.3648,73.6148,60.4042,70.846,"Phenylalanine metabolism [PATH:ko00360]","Phenylalanine metabolism ","Amino acid metabolism","Metabolism"]
["ko00361",35.6828,34.9621,34.2042,34.5525,43.218,33.0368,41.9279,30.3619,40.1322,"Chlorocyclohexane and chlorobenzene degradation [PATH:ko00361]","Chlorocyclohexane and chlorobenzene degradation ","Xenobiotics biodegradation and metabolism","Metabolism"]
["ko00362",48.2382,49.505,52.2002,51.1584,59.1414,48.4517,67.9843,46.9715,61.3126,"Benzoate degradation [PATH:ko00362]","Benzoate degradation ","Xenobiotics biodegradation and metabolism","Metabolism"]
["ko00363",12.476,10.983,12.918,18.113,12.189,12.268,14.105,10.453,13.746,"Bisphenol degradation [PATH:ko00363]","Bisphenol degradation ","Xenobiotics biodegradation and metabolism","Metabolism"]
["ko00364",51.5502,48.585,46.6574,44.6828,62.2149,43.2683,58.478,39.3741,55.6822,"Fluorobenzoate degradation [PATH:ko00364]","Fluorobenzoate degradation ","Xenobiotics biodegradation and metabolism","Metabolism"]
["ko00365",8.4295,8.983,6.7055,8.1032,11.74,7.3215,7.4907,8.2292,9.376,"Furfural degradation [PATH:ko00365]","Furfural degradation ","Xenobiotics biodegradation and metabolism","Metabolism"]
["ko00380",75.7828,77.3598,81.9537,79.3337,87.2216,78.3522,109.7505,72.466,94.7911,"Tryptophan metabolism [PATH:ko00380]","Tryptophan metabolism ","Amino acid metabolism","Metabolism"]
["ko00400",53.0722,54.5439,62.0176,57.4295,69.8533,61.4729,82.5091,61.9072,73.2152,"Phenylalanine, tyrosine and tryptophan biosynthesis [PATH:ko00400]","Phenylalanine, tyrosine and tryptophan biosynthesis ","Amino acid metabolism","Metabolism"]
["ko00404",2.0878,2.3653,3.6298,3.8424,1.9176,2.955,4.7088,5.1256,4.2251,"Staurosporine biosynthesis [PATH:ko00404]","Staurosporine biosynthesis ","Biosynthesis of other secondary metabolites","Metabolism"]
["ko00410",76.5244,77.6556,77.3334,75.2718,81.6911,75.0243,95.3554,68.1393,92.4264,"beta-Alanine metabolism [PATH:ko00410]","beta-Alanine metabolism ","Metabolism of other amino acids","Metabolism"]
["ko00430",68.2746,66.6402,71.7823,67.2319,86.796,66.492,101.7797,62.1992,80.3878,"Taurine and hypotaurine metabolism [PATH:ko00430]","Taurine and hypotaurine metabolism ","Metabolism of other amino acids","Metabolism"]
["ko00440",8.7917,8.9468,10.8568,11.5858,9.933,9.9428,10.6281,11.6052,12.7455,"Phosphonate and phosphinate metabolism [PATH:ko00440]","Phosphonate and phosphinate metabolism ","Metabolism of other amino acids","Metabolism"]
["ko00450",134.1555,132.8096,125.2175,112.2978,164.3232,129.5607,185.7781,117.1255,147.6507,"Selenocompound metabolism [PATH:ko00450]","Selenocompound metabolism ","Metabolism of other amino acids","Metabolism"]
["ko00460",56.8546,56.1236,57.1728,53.9275,59.0129,60.5572,72.7923,66.2949,65.8432,"Cyanoamino acid metabolism [PATH:ko00460]","Cyanoamino acid metabolism ","Metabolism of other amino acids","Metabolism"]
["ko00471",95.8892,96.071,103.8606,91.574,112.2378,97.3452,153.9878,80.0666,122.5082,"D-Glutamine and D-glutamate metabolism [PATH:ko00471]","D-Glutamine and D-glutamate metabolism ","Metabolism of other amino acids","Metabolism"]
["ko00473",83.239,85.8693,117.5943,105.268,113.6653,101.874,166.981,87.178,129.1423,"D-Alanine metabolism [PATH:ko00473]","D-Alanine metabolism ","Metabolism of other amino acids","Metabolism"]
["ko00480",78.0392,78.137,96.7993,96.2026,101.1109,83.3866,117.0168,96.007,106.666,"Glutathione metabolism [PATH:ko00480]","Glutathione metabolism ","Metabolism of other amino acids","Metabolism"]
["ko00500",59.1149,57.2975,51.5297,49.7794,55.2644,58.9995,61.212,61.6776,58.8449,"Starch and sucrose metabolism [PATH:ko00500]","Starch and sucrose metabolism ","Carbohydrate metabolism","Metabolism"]
["ko00510",5.7523,6.0883,7.9731,7.411,7.5073,7.7403,9.0718,8.0795,6.924,"N-Glycan biosynthesis [PATH:ko00510]","N-Glycan biosynthesis ","Glycan biosynthesis and metabolism","Metabolism"]
["ko00511",40.1242,39.1073,40.4913,41.0464,28.4521,42.6739,29.8063,60.9389,41.6599,"Other glycan degradation [PATH:ko00511]","Other glycan degradation ","Glycan biosynthesis and metabolism","Metabolism"]
["ko00513",0,0,3.1018,3.2346,1.5588,2.1645,0,3.3204,2.713,"Various types of N-glycan biosynthesis [PATH:ko00513]","Various types of N-glycan biosynthesis ","Glycan biosynthesis and metabolism","Metabolism"]
["ko00514",0.0027,0,0.4863,0.8246,0,0.0424,0.0446,0.134,0.2231,"Other types of O-glycan biosynthesis [PATH:ko00514]","Other types of O-glycan biosynthesis ","Glycan biosynthesis and metabolism","Metabolism"]
["ko00520",56.4495,55.4528,57.5507,52.3378,64.1436,59.1905,76.4663,59.8281,66.4616,"Amino sugar and nucleotide sugar metabolism [PATH:ko00520]","Amino sugar and nucleotide sugar metabolism ","Carbohydrate metabolism","Metabolism"]
["ko00521",115.3106,108.8844,114.6087,106.2109,126.0044,115.1892,145.9236,122.9307,130.9823,"Streptomycin biosynthesis [PATH:ko00521]","Streptomycin biosynthesis ","Biosynthesis of other secondary metabolites","Metabolism"]
["ko00523",21.4392,20.5927,22.0198,20.2987,23.4794,23.0562,29.4316,24.1303,24.952,"Polyketide sugar unit biosynthesis [PATH:ko00523]","Polyketide sugar unit biosynthesis ","Metabolism of terpenoids and polyketides","Metabolism"]
["ko00531",17.5502,19.0245,21.3199,20.3323,15.66,20.3791,20.8375,23.6645,22.4226,"Glycosaminoglycan degradation [PATH:ko00531]","Glycosaminoglycan degradation ","Glycan biosynthesis and metabolism","Metabolism"]
["ko00532",0.0037,0.0098,0.713,0,0.0047,0.1098,0,0,0,"Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate [PATH:ko00532]","Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate ","Glycan biosynthesis and metabolism","Metabolism"]
["ko00534",0,0,0,0.9079,0,0,0,0.1695,0.2115,"Glycosaminoglycan biosynthesis - heparan sulfate / heparin [PATH:ko00534]","Glycosaminoglycan biosynthesis - heparan sulfate / heparin ","Glycan biosynthesis and metabolism","Metabolism"]
["ko00540",36.4196,34.5625,40.6108,35.0549,45.8194,40.5089,51.2202,42.4826,46.6131,"Lipopolysaccharide biosynthesis [PATH:ko00540]","Lipopolysaccharide biosynthesis ","Glycan biosynthesis and metabolism","Metabolism"]
["ko00550",61.0293,62.4118,79.1166,76.7768,77.4356,73.4336,105.1035,69.7112,88.943,"Peptidoglycan biosynthesis [PATH:ko00550]","Peptidoglycan biosynthesis ","Glycan biosynthesis and metabolism","Metabolism"]
["ko00561",24.8418,25.2644,26.7462,26.8368,24.7429,26.4654,31.3894,28.1998,31.6145,"Glycerolipid metabolism [PATH:ko00561]","Glycerolipid metabolism ","Lipid metabolism","Metabolism"]
["ko00562",25.2142,25.3223,20.9128,20.9554,23.7321,23.3568,26.2167,25.6763,24.6946,"Inositol phosphate metabolism [PATH:ko00562]","Inositol phosphate metabolism ","Carbohydrate metabolism","Metabolism"]
["ko00563",0.0076,0.0026,0.6248,0.8318,0.07,0.0281,0.263,0.1546,0.3179,"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis [PATH:ko00563]","Glycosylphosphatidylinositol (GPI)-anchor biosynthesis ","Glycan biosynthesis and metabolism","Metabolism"]
["ko00564",21.2097,21.6768,24.9108,25.7271,25.0476,23.4844,28.4853,27.4833,28.6059,"Glycerophospholipid metabolism [PATH:ko00564]","Glycerophospholipid metabolism ","Lipid metabolism","Metabolism"]
["ko00565",18.2597,18.5264,10.0123,9.9609,13.293,15.2901,4.3227,0,12.0769,"Ether lipid metabolism [PATH:ko00565]","Ether lipid metabolism ","Lipid metabolism","Metabolism"]
["ko00590",6.7503,6.6637,9.0963,10.0192,9.677,7.434,11.279,9.4676,9.932,"Arachidonic acid metabolism [PATH:ko00590]","Arachidonic acid metabolism ","Lipid metabolism","Metabolism"]
["ko00591",0.6921,1.1025,2.4443,2.7592,1.4212,1.4655,2.4882,1.6691,2.2881,"Linoleic acid metabolism [PATH:ko00591]","Linoleic acid metabolism ","Lipid metabolism","Metabolism"]
["ko00592",12.2164,13.2002,14.4961,13.9935,12.8582,14.0079,19.1604,13.0156,16.9569,"alpha-Linolenic acid metabolism [PATH:ko00592]","alpha-Linolenic acid metabolism ","Lipid metabolism","Metabolism"]
["ko00600",30.867,29.7115,20.3245,17.9901,51.5021,19.9523,34.5054,24.5169,23.1058,"Sphingolipid metabolism [PATH:ko00600]","Sphingolipid metabolism ","Lipid metabolism","Metabolism"]
["ko00601",0,0,0.0235,0.0712,0,0.0039,0,0.0104,0,"Glycosphingolipid biosynthesis - lacto and neolacto series [PATH:ko00601]","Glycosphingolipid biosynthesis - lacto and neolacto series ","Glycan biosynthesis and metabolism","Metabolism"]
["ko00620",117.7757,116.3952,119.8039,112.4303,146.0138,118.8742,171.5394,109.7206,140.3902,"Pyruvate metabolism [PATH:ko00620]","Pyruvate metabolism ","Carbohydrate metabolism","Metabolism"]
["ko00621",9.7039,10.1311,10.548,12.8476,13.1004,9.463,10.1529,11.6881,13.0312,"Dioxin degradation [PATH:ko00621]","Dioxin degradation ","Xenobiotics biodegradation and metabolism","Metabolism"]
["ko00622",15.1164,15.9559,15.3669,18.4671,18.5017,14.7934,16.1103,18.4472,19.2772,"Xylene degradation [PATH:ko00622]","Xylene degradation ","Xenobiotics biodegradation and metabolism","Metabolism"]
["ko00623",18.0979,16.8681,17.3922,17.7131,20.6157,16.0706,21.3261,15.701,20.4584,"Toluene degradation [PATH:ko00623]","Toluene degradation ","Xenobiotics biodegradation and metabolism","Metabolism"]
["ko00624",10.73,10.5228,13.1903,11.0562,17.3643,10.6445,18.2472,10.3058,14.27,"Polycyclic aromatic hydrocarbon degradation [PATH:ko00624]","Polycyclic aromatic hydrocarbon degradation ","Xenobiotics biodegradation and metabolism","Metabolism"]
["ko00626",34.2543,33.5842,27.9197,27.5009,38.1767,30.4999,31.9185,27.2541,30.6795,"Naphthalene degradation [PATH:ko00626]","Naphthalene degradation ","Xenobiotics biodegradation and metabolism","Metabolism"]
["ko00627",31.5035,32.3618,32.5666,31.3524,42.207,31.2989,45.151,29.4976,37.7677,"Aminobenzoate degradation [PATH:ko00627]","Aminobenzoate degradation ","Xenobiotics biodegradation and metabolism","Metabolism"]
["ko00630",119.7104,119.0341,122.0601,114.5141,140.3608,120.6753,165.9337,109.2257,143.7705,"Glyoxylate and dicarboxylate metabolism [PATH:ko00630]","Glyoxylate and dicarboxylate metabolism ","Carbohydrate metabolism","Metabolism"]
["ko00633",18.0344,16.1909,16.7133,16.1375,19.0355,16.9042,14.6752,14.0848,20.4167,"Nitrotoluene degradation [PATH:ko00633]","Nitrotoluene degradation ","Xenobiotics biodegradation and metabolism","Metabolism"]
["ko00640",80.7793,81.0453,80.9041,76.1297,94.8024,80.3002,110.7319,69.3371,96.4335,"Propanoate metabolism [PATH:ko00640]","Propanoate metabolism ","Carbohydrate metabolism","Metabolism"]
["ko00642",21.0504,22.3656,22.2746,19.7242,22.4646,22.2224,28.924,20.0742,26.9404,"Ethylbenzene degradation [PATH:ko00642]","Ethylbenzene degradation ","Xenobiotics biodegradation and metabolism","Metabolism"]
["ko00643",58.9354,60.0414,58.1668,56.7503,72.964,59.7559,77.1154,53.6965,69.7714,"Styrene degradation [PATH:ko00643]","Styrene degradation ","Xenobiotics biodegradation and metabolism","Metabolism"]
["ko00650",93.2433,92.1667,94.0577,89.0072,114.8916,90.6791,126.9659,84.5757,108.8624,"Butanoate metabolism [PATH:ko00650]","Butanoate metabolism ","Carbohydrate metabolism","Metabolism"]
["ko00660",98.0722,95.8777,100.7881,90.4873,134.4442,97.0947,149.0065,87.1602,113.3899,"C5-Branched dibasic acid metabolism [PATH:ko00660]","C5-Branched dibasic acid metabolism ","Carbohydrate metabolism","Metabolism"]
["ko00670",87.4129,87.5548,94.0337,90.0856,106.4601,93.1314,135.9518,89.8216,111.7549,"One carbon pool by folate [PATH:ko00670]","One carbon pool by folate ","Metabolism of cofactors and vitamins","Metabolism"]
["ko00680",41.1787,40.8431,39.1371,36.7396,49.4684,40.7009,56.2354,37.8459,45.9097,"Methane metabolism [PATH:ko00680]","Methane metabolism ","Energy metabolism","Metabolism"]
["ko00710",136.6777,130.8648,126.3597,117.4855,157.0767,131.0668,179.3536,118.421,149.0202,"Carbon fixation in photosynthetic organisms [PATH:ko00710]","Carbon fixation in photosynthetic organisms ","Energy metabolism","Metabolism"]
["ko00720",102.0237,99.9883,100.9365,90.4256,126.7863,100.9252,147.6346,89.2875,118.0948,"Carbon fixation pathways in prokaryotes [PATH:ko00720]","Carbon fixation pathways in prokaryotes ","Energy metabolism","Metabolism"]
["ko00730",52.5504,52.6001,55.9268,54.0084,65.337,57.8142,69.0173,54.0447,63.8489,"Thiamine metabolism [PATH:ko00730]","Thiamine metabolism ","Metabolism of cofactors and vitamins","Metabolism"]
["ko00740",24.0923,24.1346,27.8996,27.6375,26.9046,27.3274,31.8484,26.7187,30.7936,"Riboflavin metabolism [PATH:ko00740]","Riboflavin metabolism ","Metabolism of cofactors and vitamins","Metabolism"]
["ko00750",58.3176,61.0135,65.6741,58.2454,71.2348,66.4686,90.3998,56.2385,73.7838,"Vitamin B6 metabolism [PATH:ko00750]","Vitamin B6 metabolism ","Metabolism of cofactors and vitamins","Metabolism"]
["ko00760",38.5741,39.6609,43.0021,40.8044,44.5376,41.5523,54.3529,39.9262,48.7422,"Nicotinate and nicotinamide metabolism [PATH:ko00760]","Nicotinate and nicotinamide metabolism ","Metabolism of cofactors and vitamins","Metabolism"]
["ko00770",122.4444,122.4329,128.2108,122.1089,156.9657,129.0919,170.8547,127.5842,148.7652,"Pantothenate and CoA biosynthesis [PATH:ko00770]","Pantothenate and CoA biosynthesis ","Metabolism of cofactors and vitamins","Metabolism"]
["ko00780",125.691,127.2022,140.5118,134.1098,158.4518,137.9836,175.4081,131.6152,160.8229,"Biotin metabolism [PATH:ko00780]","Biotin metabolism ","Metabolism of cofactors and vitamins","Metabolism"]
["ko00785",38.4362,38.8348,41.8722,40.4198,45.444,42.556,66.3087,42.7843,50.8572,"Lipoic acid metabolism [PATH:ko00785]","Lipoic acid metabolism ","Metabolism of cofactors and vitamins","Metabolism"]
["ko00790",40.8206,40.0921,46.361,43.9367,47.7786,43.9064,57.9788,44.1596,52.2006,"Folate biosynthesis [PATH:ko00790]","Folate biosynthesis ","Metabolism of cofactors and vitamins","Metabolism"]
["ko00791",23.9431,23.5058,32.9796,30.0188,35.3781,23.5848,45.0519,14.6078,40.4539,"Atrazine degradation [PATH:ko00791]","Atrazine degradation ","Xenobiotics biodegradation and metabolism","Metabolism"]
["ko00830",18.3326,18.1092,14.2136,14.0411,18.9393,16.0335,15.7051,14.4587,15.7098,"Retinol metabolism [PATH:ko00830]","Retinol metabolism ","Metabolism of cofactors and vitamins","Metabolism"]
["ko00860",30.9535,30.9131,35.608,36.1126,36.9362,34.5498,41.3253,33.861,40.2028,"Porphyrin and chlorophyll metabolism [PATH:ko00860]","Porphyrin and chlorophyll metabolism ","Metabolism of cofactors and vitamins","Metabolism"]
["ko00900",59.3917,61.8724,64.7198,62.3947,71.5992,66.5458,85.7987,60.6962,76.9714,"Terpenoid backbone biosynthesis [PATH:ko00900]","Terpenoid backbone biosynthesis ","Metabolism of terpenoids and polyketides","Metabolism"]
["ko00901",0,0,0,0,2.2763,0,0,0,0,"Indole alkaloid biosynthesis [PATH:ko00901]","Indole alkaloid biosynthesis ","Biosynthesis of other secondary metabolites","Metabolism"]
["ko00902",0.0843,0.1048,0.4159,0.489,0.1843,0.0717,0.1011,0.1394,0.1697,"Monoterpenoid biosynthesis [PATH:ko00902]","Monoterpenoid biosynthesis ","Metabolism of terpenoids and polyketides","Metabolism"]
["ko00903",121.8845,125.651,141.4317,147.9465,137.0703,130.6008,170.6115,116.7917,169.1183,"Limonene and pinene degradation [PATH:ko00903]","Limonene and pinene degradation ","Metabolism of terpenoids and polyketides","Metabolism"]
["ko00904",0.0072,0.0036,0.4833,0.5335,0.1104,0.0269,0.0011,0.0906,0.1647,"Diterpenoid biosynthesis [PATH:ko00904]","Diterpenoid biosynthesis ","Metabolism of terpenoids and polyketides","Metabolism"]
["ko00905",0.017,0.0248,0.3185,0.6533,0,0,0.0152,0.0248,0.1067,"Brassinosteroid biosynthesis [PATH:ko00905]","Brassinosteroid biosynthesis ","Metabolism of terpenoids and polyketides","Metabolism"]
["ko00906",3.1855,3.3778,4.6806,5.2224,3.0549,4.1936,4.285,3.8988,4.721,"Carotenoid biosynthesis [PATH:ko00906]","Carotenoid biosynthesis ","Metabolism of terpenoids and polyketides","Metabolism"]
["ko00908",16.8222,18.147,17.7872,17.4894,19.393,19.6824,24.6258,20.8776,21.4672,"Zeatin biosynthesis [PATH:ko00908]","Zeatin biosynthesis ","Metabolism of terpenoids and polyketides","Metabolism"]
["ko00909",3.0552,2.9556,2.0326,1.9508,3.3775,2.9313,2.0766,3.4468,2.3877,"Sesquiterpenoid and triterpenoid biosynthesis [PATH:ko00909]","Sesquiterpenoid and triterpenoid biosynthesis ","Metabolism of terpenoids and polyketides","Metabolism"]
["ko00910",61.2653,59.6348,70.4614,70.5855,86.0174,65.8645,111.91,63.7332,79.853,"Nitrogen metabolism [PATH:ko00910]","Nitrogen metabolism ","Energy metabolism","Metabolism"]
["ko00920",37.1583,35.7248,44.5361,43.6976,49.6774,39.4033,55.6315,38.707,49.9227,"Sulfur metabolism [PATH:ko00920]","Sulfur metabolism ","Energy metabolism","Metabolism"]
["ko00930",48.7067,49.9329,62.3663,68.2935,66.7567,53.2466,73.9166,51.9177,68.7982,"Caprolactam degradation [PATH:ko00930]","Caprolactam degradation ","Xenobiotics biodegradation and metabolism","Metabolism"]
["ko00940",32.3383,32.2326,31.5781,33.1079,25.2509,35.765,34.5356,44.3656,34.7948,"Phenylpropanoid biosynthesis [PATH:ko00940]","Phenylpropanoid biosynthesis ","Biosynthesis of other secondary metabolites","Metabolism"]
["ko00941",0,0,1.4274,1.1627,0,1.8967,0,1.7344,1.3456,"Flavonoid biosynthesis [PATH:ko00941]","Flavonoid biosynthesis ","Biosynthesis of other secondary metabolites","Metabolism"]
["ko00942",0,0.0041,0,0.027,0,0,0,0.0035,0.0056,"Anthocyanin biosynthesis [PATH:ko00942]","Anthocyanin biosynthesis ","Biosynthesis of other secondary metabolites","Metabolism"]
["ko00943",0.5431,0.7062,1.1089,0.8674,1.2816,1.207,1.3491,0.9066,0.9582,"Isoflavonoid biosynthesis [PATH:ko00943]","Isoflavonoid biosynthesis ","Biosynthesis of other secondary metabolites","Metabolism"]
["ko00960",23.7068,23.8018,29.6781,29.5125,32.5568,25.9767,39.507,31.3315,33.8846,"Tropane, piperidine and pyridine alkaloid biosynthesis [PATH:ko00960]","Tropane, piperidine and pyridine alkaloid biosynthesis ","Biosynthesis of other secondary metabolites","Metabolism"]
["ko00965",0,10.8552,0,8.7025,0,0,0,0,0,"Betalain biosynthesis [PATH:ko00965]","Betalain biosynthesis ","Biosynthesis of other secondary metabolites","Metabolism"]
["ko00970",130.3242,127.1092,137.5391,127.6758,164.9121,139.7193,204.7753,131.7591,162.3907,"Aminoacyl-tRNA biosynthesis [PATH:ko00970]","Aminoacyl-tRNA biosynthesis ","Translation","Genetic Information Processing"]
["ko00981",49.6276,47.9891,52.5851,50.5932,0,48.9947,66.0544,44.427,64.5253,"Insect hormone biosynthesis [PATH:ko00981]","Insect hormone biosynthesis ","Metabolism of terpenoids and polyketides","Metabolism"]
["ko00982",70.6325,72.0725,87.0658,92.7258,89.1354,72.133,89.0462,90.784,94.7972,"Drug metabolism - cytochrome P450 [PATH:ko00982]","Drug metabolism - cytochrome P450 ","Xenobiotics biodegradation and metabolism","Metabolism"]
["ko00983",97.5359,96.2401,118.8737,118.9832,123.9319,106.9022,151.8067,121.286,132.9155,"Drug metabolism - other enzymes [PATH:ko00983]","Drug metabolism - other enzymes ","Xenobiotics biodegradation and metabolism","Metabolism"]
["ko00984",12.1686,14.3006,10.3159,14.5964,10.8601,14.4288,11.91,17.6928,13.3406,"Steroid degradation [PATH:ko00984]","Steroid degradation ","Xenobiotics biodegradation and metabolism","Metabolism"]
["ko00998",0.8671,0.7982,1.2049,1.1416,1.2226,0.8843,1.6159,1.0037,1.1932,"Biosynthesis of various secondary metabolites - part 2 [PATH:ko00998]","Biosynthesis of various secondary metabolites - part 2 ","Biosynthesis of other secondary metabolites","Metabolism"]
["ko01040",15.9188,16.3507,20.8709,21.7814,21.4079,18.6139,28.5053,20.2298,23.059,"Biosynthesis of unsaturated fatty acids [PATH:ko01040]","Biosynthesis of unsaturated fatty acids ","Lipid metabolism","Metabolism"]
["ko01051",29.0157,27.7966,22.9401,21.5216,30.96,26.6819,30.5546,24.3741,28.6032,"Biosynthesis of ansamycins [PATH:ko01051]","Biosynthesis of ansamycins ","Metabolism of terpenoids and polyketides","Metabolism"]
["ko01052",0.1679,0.1606,0.1271,0.1529,0.3395,0.3337,0.5299,0.2209,0.1383,"Type I polyketide structures [PATH:ko01052]","Type I polyketide structures ","Metabolism of terpenoids and polyketides","Metabolism"]
["ko01053",2.3711,2.8705,3.1213,3.3942,2.5597,3.0929,2.3381,3.2189,3.0997,"Biosynthesis of siderophore group nonribosomal peptides [PATH:ko01053]","Biosynthesis of siderophore group nonribosomal peptides ","Metabolism of terpenoids and polyketides","Metabolism"]
["ko01054",1.4946,1.4887,1.8004,1.8941,1.707,1.4952,1.8241,1.5795,2.1039,"Nonribosomal peptide structures [PATH:ko01054]","Nonribosomal peptide structures ","Metabolism of terpenoids and polyketides","Metabolism"]
["ko01055",20.8237,20.5655,20.0881,18.3112,24.6777,21.3382,29.3513,21.5999,22.8443,"Biosynthesis of vancomycin group antibiotics [PATH:ko01055]","Biosynthesis of vancomycin group antibiotics ","Metabolism of terpenoids and polyketides","Metabolism"]
["ko01056",0,0,0.1472,0.245,0,0.46,0,1.1196,0.098,"Biosynthesis of type II polyketide backbone [PATH:ko01056]","Biosynthesis of type II polyketide backbone ","Metabolism of terpenoids and polyketides","Metabolism"]
["ko01057",0.3448,0.4408,0.4213,0.2647,0.3254,0.4978,0.2848,0.4242,0.4283,"Biosynthesis of type II polyketide products [PATH:ko01057]","Biosynthesis of type II polyketide products ","Metabolism of terpenoids and polyketides","Metabolism"]
["ko01501",19.3705,19.2509,26.1451,26.1786,24.7258,21.9853,31.5921,20.0279,30.2277,"beta-Lactam resistance [PATH:ko01501]","beta-Lactam resistance ","Drug resistance: antimicrobial","Human Diseases"]
["ko01502",44.8576,45.8233,57.7892,54.0803,58.7475,55.1669,79.5888,50.7743,63.7127,"Vancomycin resistance [PATH:ko01502]","Vancomycin resistance ","Drug resistance: antimicrobial","Human Diseases"]
["ko01503",24.2407,22.5724,30.3237,29.5358,30.6764,24.0524,36.8814,27.5251,35.8321,"Cationic antimicrobial peptide (CAMP) resistance [PATH:ko01503]","Cationic antimicrobial peptide (CAMP) resistance ","Drug resistance: antimicrobial","Human Diseases"]
["ko02010",26.6109,26.6279,36.2532,36.2176,40.8125,28.0959,43.5218,26.9065,42.3393,"ABC transporters [PATH:ko02010]","ABC transporters ","Membrane transport","Environmental Information Processing"]
["ko02020",31.1543,30.5803,36.3485,35.2734,40.2367,32.1748,42.7527,32.6142,42.6826,"Two-component system [PATH:ko02020]","Two-component system ","Signal transduction","Environmental Information Processing"]
["ko02024",31.9709,32.1244,37.7585,35.7584,48.3156,32.8343,46.0356,32.2223,44.6928,"Quorum sensing [PATH:ko02024]","Quorum sensing ","Cellular community - prokaryotes","Cellular Processes"]
["ko02030",77.328,76.1423,113.116,119.7032,80.3235,86.4793,103.58,92.3181,128.1232,"Bacterial chemotaxis [PATH:ko02030]","Bacterial chemotaxis ","Cell motility","Cellular Processes"]
["ko02040",31.3137,32.1148,55.6428,65.4755,44.7611,41.8164,53.0354,55.8246,63.3212,"Flagellar assembly [PATH:ko02040]","Flagellar assembly ","Cell motility","Cellular Processes"]
["ko02060",5.5794,5.4321,8.5904,9.0532,7.5445,7.4024,9.3922,7.2966,9.9915,"Phosphotransferase system (PTS) [PATH:ko02060]","Phosphotransferase system (PTS) ","Membrane transport","Environmental Information Processing"]
["ko03008",2.8494,3.1097,4.233,4.9057,3.6318,3.2325,4.6588,4.5132,4.0627,"Ribosome biogenesis in eukaryotes [PATH:ko03008]","Ribosome biogenesis in eukaryotes ","Translation","Genetic Information Processing"]
["ko03010",90.7761,92.9262,98.5927,97.466,119.533,98.1524,137.743,106.3276,116.5727,"Ribosome [PATH:ko03010]","Ribosome ","Translation","Genetic Information Processing"]
["ko03013",1.9578,2.0973,3.4371,3.1501,2.5652,1.8886,2.911,1.9974,3.1384,"RNA transport [PATH:ko03013]","RNA transport ","Translation","Genetic Information Processing"]
["ko03015",0.4266,0.4227,1.3958,2.0726,0.5102,0.2459,0.1405,0.5557,0.7047,"mRNA surveillance pathway [PATH:ko03015]","mRNA surveillance pathway ","Translation","Genetic Information Processing"]
["ko03018",61.4466,58.9067,64.3133,58.6782,82.0436,62.823,93.748,59.6102,72.9753,"RNA degradation [PATH:ko03018]","RNA degradation ","Folding, sorting and degradation","Genetic Information Processing"]
["ko03020",29.8012,28.7315,30.6137,30.0288,42.124,29.3648,44.3382,29.8971,36.7368,"RNA polymerase [PATH:ko03020]","RNA polymerase ","Transcription","Genetic Information Processing"]
["ko03022",0,0,3.0877,3.0099,0,3.1886,3.8579,3.3405,3.9922,"Basal transcription factors [PATH:ko03022]","Basal transcription factors ","Transcription","Genetic Information Processing"]
["ko03030",61.0008,62.1535,70.9211,71.3723,71.3664,69.2486,95.4639,71.9215,83.5391,"DNA replication [PATH:ko03030]","DNA replication ","Replication and repair","Genetic Information Processing"]
["ko03040",0.1394,0.088,1.1648,1.6353,0.3035,0.1798,0.1383,0.2886,0.4411,"Spliceosome [PATH:ko03040]","Spliceosome ","Transcription","Genetic Information Processing"]
["ko03050",2.9993,3.5084,2.8815,3.2371,3.9247,2.3788,2.9539,2.8165,3.1013,"Proteasome [PATH:ko03050]","Proteasome ","Folding, sorting and degradation","Genetic Information Processing"]
["ko03060",83.6138,83.4284,93.2012,93.3349,107.2984,85.7022,123.2231,91.9497,107.0388,"Protein export [PATH:ko03060]","Protein export ","Folding, sorting and degradation","Genetic Information Processing"]
["ko03070",56.8155,55.6618,71.9976,73.6924,72.7155,57.7782,80.7706,70.4679,80.8031,"Bacterial secretion system [PATH:ko03070]","Bacterial secretion system ","Membrane transport","Environmental Information Processing"]
["ko03320",39.24,39.4559,45.0233,44.7114,50.6834,41.5575,61.1167,37.7142,50.9291,"PPAR signaling pathway [PATH:ko03320]","PPAR signaling pathway ","Endocrine system","Organismal Systems"]
["ko03410",70.3825,74.1406,81.0807,76.6349,82.4301,81.6436,109.767,77.2551,94.6418,"Base excision repair [PATH:ko03410]","Base excision repair ","Replication and repair","Genetic Information Processing"]
["ko03420",75.7503,75.7794,83.0412,77.6302,91.9922,82.5075,121.1613,74.559,98.5566,"Nucleotide excision repair [PATH:ko03420]","Nucleotide excision repair ","Replication and repair","Genetic Information Processing"]
["ko03430",91.977,92.543,108.9088,105.6173,106.5508,106.599,145.2336,107.091,126.4023,"Mismatch repair [PATH:ko03430]","Mismatch repair ","Replication and repair","Genetic Information Processing"]
["ko03440",58.2669,59.5438,66.9199,68.3471,66.7364,69.0852,88.5126,69.5137,76.5306,"Homologous recombination [PATH:ko03440]","Homologous recombination ","Replication and repair","Genetic Information Processing"]
["ko03450",38.557,38.6193,47.2343,40.1249,37.7336,38.648,52.4832,28.4532,49.8377,"Non-homologous end-joining [PATH:ko03450]","Non-homologous end-joining ","Replication and repair","Genetic Information Processing"]
["ko03460",0.4891,0.5224,0.9997,1.0988,1.1551,0.352,0.6368,0.6624,0.8468,"Fanconi anemia pathway [PATH:ko03460]","Fanconi anemia pathway ","Replication and repair","Genetic Information Processing"]
["ko04010",0,0,0.2843,0.3822,0.0053,0.0298,0,0.0817,0.0737,"MAPK signaling pathway [PATH:ko04010]","MAPK signaling pathway ","Signal transduction","Environmental Information Processing"]
["ko04011",0,0,2.5818,2.8628,0,0,0,1.9915,2.8106,"MAPK signaling pathway - yeast [PATH:ko04011]","MAPK signaling pathway - yeast ","Signal transduction","Environmental Information Processing"]
["ko04013",0,0,0,0,0,4.9204,0,0,0,"MAPK signaling pathway - fly [PATH:ko04013]","MAPK signaling pathway - fly ","Signal transduction","Environmental Information Processing"]
["ko04014",0,0,0.3724,0.3616,0,0.0243,0,0.0901,0.088,"Ras signaling pathway [PATH:ko04014]","Ras signaling pathway ","Signal transduction","Environmental Information Processing"]
["ko04016",0,0,0,0,0,0,11.7793,0,0,"MAPK signaling pathway - plant [PATH:ko04016]","MAPK signaling pathway - plant ","Signal transduction","Environmental Information Processing"]
["ko04020",0,0,0.1308,0.2171,0.0634,0,0.0455,0.0926,0.0625,"Calcium signaling pathway [PATH:ko04020]","Calcium signaling pathway ","Signal transduction","Environmental Information Processing"]
["ko04060",0,0.0018,0,0,0.001,0.0091,0,0.0066,0,"Cytokine-cytokine receptor interaction [PATH:ko04060]","Cytokine-cytokine receptor interaction ","Signaling molecules and interaction","Environmental Information Processing"]
["ko04068",8.142,0,0,0,9.6458,0,10.8896,0,10.0053,"FoxO signaling pathway [PATH:ko04068]","FoxO signaling pathway ","Signal transduction","Environmental Information Processing"]
["ko04070",6.3204,6.5448,9.5378,10.1591,0,7.1165,0,8.7132,9.7431,"Phosphatidylinositol signaling system [PATH:ko04070]","Phosphatidylinositol signaling system ","Signal transduction","Environmental Information Processing"]
["ko04075",0.0257,0.0398,2.5565,4.1409,0.023,0.1985,0,0.6643,1.1201,"Plant hormone signal transduction [PATH:ko04075]","Plant hormone signal transduction ","Signal transduction","Environmental Information Processing"]
["ko04110",0,0,1.0554,1.3031,0.111,0.1224,0,0.3098,0.3951,"Cell cycle [PATH:ko04110]","Cell cycle ","Cell growth and death","Cellular Processes"]
["ko04111",0.0222,0.0387,0.943,1.1437,0.0288,0.0878,0,0.2324,0.2847,"Cell cycle - yeast [PATH:ko04111]","Cell cycle - yeast ","Cell growth and death","Cellular Processes"]
["ko04112",116.6102,115.9196,134.0657,140.5308,146.1954,123.1688,164.9177,120.7882,152.8127,"Cell cycle - Caulobacter [PATH:ko04112]","Cell cycle - Caulobacter ","Cell growth and death","Cellular Processes"]
["ko04113",3.9225,3.9492,4.6141,4.9625,6.5533,3.0394,4.5065,2.4293,4.7328,"Meiosis - yeast [PATH:ko04113]","Meiosis - yeast ","Cell growth and death","Cellular Processes"]
["ko04115",0,3.8967,4.8416,5.215,0,3.1784,0,2.7894,0,"p53 signaling pathway [PATH:ko04115]","p53 signaling pathway ","Cell growth and death","Cellular Processes"]
["ko04120",0.0057,0.0145,0.7266,0.9465,0.0157,0.0507,0,0.1651,0.2072,"Ubiquitin mediated proteolysis [PATH:ko04120]","Ubiquitin mediated proteolysis ","Folding, sorting and degradation","Genetic Information Processing"]
["ko04122",82.4186,82.0617,80.2735,72.1868,100.7492,85.9342,109.9962,76.3649,98.0976,"Sulfur relay system [PATH:ko04122]","Sulfur relay system ","Folding, sorting and degradation","Genetic Information Processing"]
["ko04130",0,0,0.6867,0.7822,0,0.0318,0,0.1039,0.1658,"SNARE interactions in vesicular transport [PATH:ko04130]","SNARE interactions in vesicular transport ","Folding, sorting and degradation","Genetic Information Processing"]
["ko04136",0.0182,0,0.5947,0.9628,0.0087,0.1398,0,0.2566,0.2011,"Autophagy - other [PATH:ko04136]","Autophagy - other ","Transport and catabolism","Cellular Processes"]
["ko04137",0,0,0,0.4141,0,0,0,0,0,"Mitophagy - animal [PATH:ko04137]","Mitophagy - animal ","Transport and catabolism","Cellular Processes"]
["ko04139",0.0081,0.0709,0.7166,1.0681,0.0224,0.0824,0,0.1763,0.3176,"Mitophagy - yeast [PATH:ko04139]","Mitophagy - yeast ","Transport and catabolism","Cellular Processes"]
["ko04141",3.1376,3.0721,4.0107,4.5201,4.5227,3.5025,4.4564,4.6264,4.1177,"Protein processing in endoplasmic reticulum [PATH:ko04141]","Protein processing in endoplasmic reticulum ","Folding, sorting and degradation","Genetic Information Processing"]
["ko04142",5.6049,5.4747,5.7078,5.4655,4.1795,5.8995,4.6789,8.6604,6.1071,"Lysosome [PATH:ko04142]","Lysosome ","Transport and catabolism","Cellular Processes"]
["ko04144",0.0192,0,1.0165,1.2317,0.0215,0.0562,0,0.2158,0.2857,"Endocytosis [PATH:ko04144]","Endocytosis ","Transport and catabolism","Cellular Processes"]
["ko04146",30.6742,29.6795,37.5641,35.3085,40.5494,32.716,47.9696,30.4291,42.1071,"Peroxisome [PATH:ko04146]","Peroxisome ","Transport and catabolism","Cellular Processes"]
["ko04151",0,0,1.6643,1.7357,0,1.4905,0,1.7946,1.8091,"PI3K-Akt signaling pathway [PATH:ko04151]","PI3K-Akt signaling pathway ","Signal transduction","Environmental Information Processing"]
["ko04152",12.5808,11.7453,12.6912,11.6062,15.7349,12.112,18.1689,12.0793,14.2688,"AMPK signaling pathway [PATH:ko04152]","AMPK signaling pathway ","Signal transduction","Environmental Information Processing"]
["ko04210",2.4731,2.4587,3.2731,3.5127,3.3871,2.0236,3.1311,1.8809,3.4341,"Apoptosis [PATH:ko04210]","Apoptosis ","Cell growth and death","Cellular Processes"]
["ko04212",0,0,66.6809,64.4493,0,0,0,0,72.2539,"Longevity regulating pathway - worm [PATH:ko04212]","Longevity regulating pathway - worm ","Aging","Organismal Systems"]
["ko04213",26.4155,25.0974,28.5331,26.9559,33.9651,24.3161,35.0167,21.0202,32.1,"Longevity regulating pathway - multiple species [PATH:ko04213]","Longevity regulating pathway - multiple species ","Aging","Organismal Systems"]
["ko04214",6.754,6.4622,8.841,9.4642,8.0601,6.3833,9.145,7.668,9.8281,"Apoptosis - fly [PATH:ko04214]","Apoptosis - fly ","Cell growth and death","Cellular Processes"]
["ko04310",0.2961,0.2036,0.4849,0.6472,0.2831,0.4252,0.2027,0.7094,0.3707,"Wnt signaling pathway [PATH:ko04310]","Wnt signaling pathway ","Signal transduction","Environmental Information Processing"]
["ko04320",0,0,0.6159,0.5304,0,0,0,0.1215,0.2239,"Dorso-ventral axis formation [PATH:ko04320]","Dorso-ventral axis formation ","Development and regeneration","Organismal Systems"]
["ko04341",0.0034,0.0242,1.9279,2.176,0,0.1415,0.0201,0.4505,0.5635,"Hedgehog signaling pathway - fly [PATH:ko04341]","Hedgehog signaling pathway - fly ","Signal transduction","Environmental Information Processing"]
["ko04361",2.1264,0,0,0,2.3934,0,0,0,0,"Axon regeneration [PATH:ko04361]","Axon regeneration ","Development and regeneration","Organismal Systems"]
["ko04371",0,0,0,0,0.1803,0,0,0,0,"Apelin signaling pathway [PATH:ko04371]","Apelin signaling pathway ","Signal transduction","Environmental Information Processing"]
["ko04391",0,0,0.2206,0.4012,0,0.0448,0,0.0399,0.0587,"Hippo signaling pathway - fly [PATH:ko04391]","Hippo signaling pathway - fly ","Signal transduction","Environmental Information Processing"]
["ko04514",0.1665,0.1198,0.1183,0.1841,0.1414,0.3243,0.0979,0.4983,0.1666,"Cell adhesion molecules (CAMs) [PATH:ko04514]","Cell adhesion molecules (CAMs) ","Signaling molecules and interaction","Environmental Information Processing"]
["ko04530",0,0,0.3432,0,0.1024,0.0649,0,0.1117,0.1135,"Tight junction [PATH:ko04530]","Tight junction ","Cellular community - eukaryotes","Cellular Processes"]
["ko04550",0.1819,0,0.3018,0.3743,0,0.3556,0,0,0,"Signaling pathways regulating pluripotency of stem cells [PATH:ko04550]","Signaling pathways regulating pluripotency of stem cells ","Cellular community - eukaryotes","Cellular Processes"]
["ko04612",0,0,0,4.7668,0,0,0,0,0,"Antigen processing and presentation [PATH:ko04612]","Antigen processing and presentation ","Immune system","Organismal Systems"]
["ko04614",21.2406,19.1931,21.2245,17.7713,23.0406,18.0987,28.9973,15.3681,23.5352,"Renin-angiotensin system [PATH:ko04614]","Renin-angiotensin system ","Endocrine system","Organismal Systems"]
["ko04622",0,0,0.2125,0.3716,0,0.206,0,0.3078,0.1893,"RIG-I-like receptor signaling pathway [PATH:ko04622]","RIG-I-like receptor signaling pathway ","Immune system","Organismal Systems"]
["ko04626",7.3459,7.6677,11.639,12.5317,9.6903,9.0904,12.7143,10.4919,11.8924,"Plant-pathogen interaction [PATH:ko04626]","Plant-pathogen interaction ","Environmental adaptation","Organismal Systems"]
["ko04712",0.0276,0.0549,0.9528,1.2631,0.0391,0.0804,0.0386,0.1932,0.2134,"Circadian rhythm - plant [PATH:ko04712]","Circadian rhythm - plant ","Environmental adaptation","Organismal Systems"]
["ko04721",0.1364,0.1021,1.2145,1.5925,0,0.1493,0,0.3801,0.5229,"Synaptic vesicle cycle [PATH:ko04721]","Synaptic vesicle cycle ","Nervous system","Organismal Systems"]
["ko04723",0.3471,0.4188,1.5817,1.8016,0.4826,0.6117,0.4424,1.202,0.8594,"Retrograde endocannabinoid signaling [PATH:ko04723]","Retrograde endocannabinoid signaling ","Nervous system","Organismal Systems"]
["ko04725",0,0,0,0,0,0,0.063,0,0,"Cholinergic synapse [PATH:ko04725]","Cholinergic synapse ","Nervous system","Organismal Systems"]
["ko04740",0.213,0.1232,0.3444,0.3952,0.1634,0.2248,0.1482,0.4512,0.1462,"Olfactory transduction [PATH:ko04740]","Olfactory transduction ","Sensory system","Organismal Systems"]
["ko04742",4.1696,3.0137,2.3885,5.9468,2.7682,9.092,2.7078,14.1769,5.7544,"Taste transduction [PATH:ko04742]","Taste transduction ","Sensory system","Organismal Systems"]
["ko04910",11.7088,10.5142,10.7375,9.5139,15.154,10.7913,14.7775,9.6955,12.1901,"Insulin signaling pathway [PATH:ko04910]","Insulin signaling pathway ","Endocrine system","Organismal Systems"]
["ko04915",1.5446,1.5385,2.5589,2.8135,0,1.9472,3.2619,2.7477,2.6959,"Estrogen signaling pathway [PATH:ko04915]","Estrogen signaling pathway ","Endocrine system","Organismal Systems"]
["ko04919",5.5826,5.6198,2.5821,2.8023,3.7228,4.4143,0.5755,6.5664,3.5355,"Thyroid hormone signaling pathway [PATH:ko04919]","Thyroid hormone signaling pathway ","Endocrine system","Organismal Systems"]
["ko04922",0,39.784,40.5594,37.2366,0,42.0455,0,39.5312,0,"Glucagon signaling pathway [PATH:ko04922]","Glucagon signaling pathway ","Endocrine system","Organismal Systems"]
["ko04925",0,0,0,0,0.1143,0,0,0.1369,0,"Aldosterone synthesis and secretion [PATH:ko04925]","Aldosterone synthesis and secretion ","Endocrine system","Organismal Systems"]
["ko04928",0.0309,0,0,0,0,0,0.0107,0,0,"Parathyroid hormone synthesis, secretion and action [PATH:ko04928]","Parathyroid hormone synthesis, secretion and action ","Endocrine system","Organismal Systems"]
["ko04931",0,0,17.5013,15.1454,0,18.2883,0,0,20.9978,"Insulin resistance [PATH:ko04931]","Insulin resistance ","Endocrine and metabolic disease","Human Diseases"]
["ko04962",0.313,0.3033,0.5677,0.8127,0.5099,0.3152,0.1964,0,0.411,"Vasopressin-regulated water reabsorption [PATH:ko04962]","Vasopressin-regulated water reabsorption ","Excretory system","Organismal Systems"]
["ko04970",0.022,0.0062,0.0469,0.1039,0,0.0332,0,0.051,0.0726,"Salivary secretion [PATH:ko04970]","Salivary secretion ","Digestive system","Organismal Systems"]
["ko04974",1.874,1.9938,2.678,2.3966,2.4279,2.2242,2.9185,1.837,2.649,"Protein digestion and absorption [PATH:ko04974]","Protein digestion and absorption ","Digestive system","Organismal Systems"]
["ko04976",1.0171,1.0438,1.7478,1.9287,1.2207,1.2847,0,1.1503,1.1293,"Bile secretion [PATH:ko04976]","Bile secretion ","Digestive system","Organismal Systems"]
["ko04977",0.0496,0.0177,0.2129,0.312,0.064,0.0443,0.0782,0.0737,0.0596,"Vitamin digestion and absorption [PATH:ko04977]","Vitamin digestion and absorption ","Digestive system","Organismal Systems"]
["ko04978",0.1915,0.1799,1.8761,2.2469,0.3971,0.4467,0.7416,0.6507,1.8552,"Mineral absorption [PATH:ko04978]","Mineral absorption ","Digestive system","Organismal Systems"]
["ko05010",6.6006,6.8044,8.5489,8.8323,8.9848,6.6285,0,7.8782,8.888,"Alzheimer disease [PATH:ko05010]","Alzheimer disease ","Neurodegenerative disease","Human Diseases"]
["ko05014",16.4424,0,18.5475,20.0213,0,0,0,16.2441,21.0819,"Amyotrophic lateral sclerosis (ALS) [PATH:ko05014]","Amyotrophic lateral sclerosis (ALS) ","Neurodegenerative disease","Human Diseases"]
["ko05016",7.1304,7.0014,0,0,0,6.8205,0,0,0,"Huntington disease [PATH:ko05016]","Huntington disease ","Neurodegenerative disease","Human Diseases"]
["ko05020",0,0,3.6813,3.6882,0,0,0,1.9377,0,"Prion diseases [PATH:ko05020]","Prion diseases ","Neurodegenerative disease","Human Diseases"]
["ko05034",0,2.0711,0,2.8357,0,0,0,1.9592,0,"Alcoholism [PATH:ko05034]","Alcoholism ","Substance dependence","Human Diseases"]
["ko05100",0.2318,0.1995,0.6385,0.6213,0.1609,0.1987,0.0571,0.388,0.3066,"Bacterial invasion of epithelial cells [PATH:ko05100]","Bacterial invasion of epithelial cells ","Infectious disease: bacterial","Human Diseases"]
["ko05110",0,0.357,0.5756,0.8233,0,0.1336,0,0.3873,0.4198,"Vibrio cholerae infection [PATH:ko05110]","Vibrio cholerae infection ","Infectious disease: bacterial","Human Diseases"]
["ko05111",18.158,17.5381,22.5633,19.9161,26.597,18.9154,27.7567,23.2629,26.1625,"Biofilm formation - Vibrio cholerae [PATH:ko05111]","Biofilm formation - Vibrio cholerae ","Cellular community - prokaryotes","Cellular Processes"]
["ko05120",2.6907,2.3488,4.3263,4.1657,3.5947,3.1473,4.6347,2.5569,4.9122,"Epithelial cell signaling in Helicobacter pylori infection [PATH:ko05120]","Epithelial cell signaling in Helicobacter pylori infection ","Infectious disease: bacterial","Human Diseases"]
["ko05130",4.4992,4.4489,5.2025,5.3485,5.7899,4.2011,6.2712,4.1471,5.5925,"Pathogenic Escherichia coli infection [PATH:ko05130]","Pathogenic Escherichia coli infection ","Infectious disease: bacterial","Human Diseases"]
["ko05132",0,0,6.0914,6.5769,0,0,0,5.1123,6.6462,"Salmonella infection [PATH:ko05132]","Salmonella infection ","Infectious disease: bacterial","Human Diseases"]
["ko05133",2.3125,2.1677,4.5816,5.2084,2.4671,2.1661,2.4274,3.5953,4.7038,"Pertussis [PATH:ko05133]","Pertussis ","Infectious disease: bacterial","Human Diseases"]
["ko05134",26.6441,26.2913,29.3618,28.7945,37.9007,25.1199,39.2229,24.6541,32.6783,"Legionellosis [PATH:ko05134]","Legionellosis ","Infectious disease: bacterial","Human Diseases"]
["ko05142",0,0,0,0,0,0,5.2066,0,0,"Chagas disease (American trypanosomiasis) [PATH:ko05142]","Chagas disease (American trypanosomiasis) ","Infectious disease: parasitic","Human Diseases"]
["ko05143",5.7454,5.5108,5.8754,5.262,5.6902,4.4329,0,4.9365,6.9534,"African trypanosomiasis [PATH:ko05143]","African trypanosomiasis ","Infectious disease: parasitic","Human Diseases"]
["ko05146",2.1701,1.9768,1.8335,1.4363,2.0179,2.0758,2.5197,2.2752,1.9705,"Amoebiasis [PATH:ko05146]","Amoebiasis ","Infectious disease: parasitic","Human Diseases"]
["ko05150",0.3957,0.4728,0.8025,1.1104,0.3755,0.5925,0.5375,1.3674,1.0311,"Staphylococcus aureus infection [PATH:ko05150]","Staphylococcus aureus infection ","Infectious disease: bacterial","Human Diseases"]
["ko05152",13.9353,13.2515,13.7967,12.8787,19.9678,12.6608,19.2082,11.9297,15.3933,"Tuberculosis [PATH:ko05152]","Tuberculosis ","Infectious disease: bacterial","Human Diseases"]
["ko05162",2.2588,2.2522,3.2328,3.6388,0,1.8587,0,1.7207,3.1275,"Measles [PATH:ko05162]","Measles ","Infectious disease: viral","Human Diseases"]
["ko05166",0,0.2669,0.7034,0.7531,0,0.1632,0,0.3268,0.4699,"Human T-cell leukemia virus 1 infection [PATH:ko05166]","Human T-cell leukemia virus 1 infection ","Infectious disease: viral","Human Diseases"]
["ko05202",0.0104,0.0065,0.1439,0.25,0,0.034,0.0208,0.0729,0.0619,"Transcriptional misregulation in cancer [PATH:ko05202]","Transcriptional misregulation in cancer ","Cancer: overview","Human Diseases"]
["ko05203",2.1442,2.184,2.7587,2.7583,2.7261,2.1347,0,2.1661,2.9188,"Viral carcinogenesis [PATH:ko05203]","Viral carcinogenesis ","Cancer: overview","Human Diseases"]
["ko05204",31.0637,32.2177,46.9746,51.0149,45.0038,35.2416,48.8475,49.7028,51.1883,"Chemical carcinogenesis [PATH:ko05204]","Chemical carcinogenesis ","Cancer: overview","Human Diseases"]
["ko05205",0,0,1.1136,1.3141,0,0,0,0,1.1399,"Proteoglycans in cancer [PATH:ko05205]","Proteoglycans in cancer ","Cancer: overview","Human Diseases"]
["ko05206",0,0.6933,1.353,1.7615,0,1.2828,0,1.9074,1.2171,"MicroRNAs in cancer [PATH:ko05206]","MicroRNAs in cancer ","Cancer: overview","Human Diseases"]
["ko05231",0,0.6473,2.3731,2.3225,1.2245,0.8274,0,1.9043,1.793,"Choline metabolism in cancer [PATH:ko05231]","Choline metabolism in cancer ","Cancer: overview","Human Diseases"]
["ko05322",0.8241,0.8933,1.5341,1.7027,1.0162,2.0239,1.4153,0.8763,1.3618,"Systemic lupus erythematosus [PATH:ko05322]","Systemic lupus erythematosus ","Immune disease","Human Diseases"]
["ko05410",1.212,0.9493,1.3348,1.06,1.4644,0.8255,2.1274,0.4326,1.2708,"Hypertrophic cardiomyopathy (HCM) [PATH:ko05410]","Hypertrophic cardiomyopathy (HCM) ","Cardiovascular disease","Human Diseases"]