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{"sheet":"Sheet1","index":0,"n_rows":133260,"n_cols":28,"rows_kept":2250,"cut":true,"bounds":{"rows_first":1000,"rows_last":250,"rows_between":1000,"halvings":1}}
["t_id","class_code","chr","strand","start","end","t_name","num_exons","length","gene_id","gene_name","GO","KEGG","KO_ENTRY","EC","Description","FPKM.D7_5ng_1","FPKM.D7_5ng_2","FPKM.D7_5ng_3","FPKM.D7_0ng_1","FPKM.D7_0ng_2","FPKM.D7_0ng_3","fc","log2(fc)","pval","qval","regulation","significant"]
[123077,0,"chr2","+",231710427,231713268,"ENST00000412128",5,863,"ENSG00000187514","PTMA","GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0006351(transcription, DNA-templated);GO:0033613(activating transcription factor binding);GO:0042393(histone binding);GO:0043066(negative regulation of apoptotic process);GO:0043486(histone exchange)","NA","NA","NA","prothymosin alpha [Source:HGNC Symbol;Acc:HGNC:9623]",0,0,0,{"v":168.200958,"d":"168.20"},{"v":199.250031,"d":"199.25"},{"v":209.963333,"d":"209.96"},"-inf","-inf",{"v":3.37011470749238e-33,"d":"0.00"},{"v":1.22436267323198e-28,"d":"0.00"},"down","yes"]
[46416,0,"chr12","-",91146058,91182805,"ENST00000547568",5,823,"ENSG00000011465","DCN","GO:0001822(kidney development);GO:0001890(placenta development);GO:0003723(RNA binding);GO:0005515(protein binding);GO:0005518(collagen binding);GO:0005539(glycosaminoglycan binding);GO:0005576(extracellular region);GO:0005589(collagen type VI trimer);GO:0005615(extracellular space);GO:0005796(Golgi lumen);GO:0007519(skeletal muscle tissue development);GO:0007568(aging);GO:0009612(response to mechanical stimulus);GO:0009887(animal organ morphogenesis);GO:0010508(positive regulation of autophagy);GO:0010596(negative regulation of endothelial cell migration);GO:0014068(positive regulation of phosphatidylinositol 3-kinase signaling);GO:0016239(positive regulation of macroautophagy);GO:0016525(negative regulation of angiogenesis);GO:0019800(peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan);GO:0030021(extracellular matrix structural constituent conferring compression resistance);GO:0030198(extracellular matrix organization);GO:0030206(chondroitin sulfate biosynthetic process);GO:0030207(chondroitin sulfate catabolic process);GO:0030208(dermatan sulfate biosynthetic process);GO:0031012(extracellular matrix);GO:0032496(response to lipopolysaccharide);GO:0042060(wound healing);GO:0043202(lysosomal lumen);GO:0045944(positive regulation of transcription by RNA polymerase II);GO:0047485(protein N-terminus binding);GO:0050840(extracellular matrix binding);GO:0051901(positive regulation of mitochondrial depolarization);GO:0062023(collagen-containing extracellular matrix);GO:0090141(positive regulation of mitochondrial fission);GO:1900747(negative regulation of vascular endothelial growth factor signaling pathway)","04350(TGF-beta signaling pathway);05205(Proteoglycans in cancer)","NA","NA","decorin [Source:HGNC Symbol;Acc:HGNC:2705]",{"v":177.705032,"d":"177.71"},{"v":188.729019,"d":"188.73"},{"v":167.34317,"d":"167.34"},0,0,0,"inf","inf",{"v":4.26473458219002e-32,"d":"0.00"},{"v":7.74689036854817e-28,"d":"0.00"},"up","yes"]
[182909,0,"chr7","-",108147662,108456339,"ENST00000351718",28,6228,"ENSG00000091129","NRCAM","GO:0001525(angiogenesis);GO:0001764(neuron migration);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0005886(plasma membrane);GO:0005887(integral component of plasma membrane);GO:0007155(cell adhesion);GO:0007409(axonogenesis);GO:0007411(axon guidance);GO:0007413(axonal fasciculation);GO:0007416(synapse assembly);GO:0007417(central nervous system development);GO:0008104(protein localization);GO:0009897(external side of plasma membrane);GO:0010975(regulation of neuron projection development);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0019227(neuronal action potential propagation);GO:0030424(axon);GO:0030506(ankyrin binding);GO:0030516(regulation of axon extension);GO:0031290(retinal ganglion cell axon guidance);GO:0034113(heterotypic cell-cell adhesion);GO:0042995(cell projection);GO:0043005(neuron projection);GO:0043194(axon initial segment);GO:0045162(clustering of voltage-gated sodium channels);GO:0045202(synapse);GO:0045666(positive regulation of neuron differentiation);GO:0086080(protein binding involved in heterotypic cell-cell adhesion);GO:0098609(cell-cell adhesion);GO:0098978(glutamatergic synapse);GO:0099055(integral component of postsynaptic membrane);GO:0099061(integral component of postsynaptic density membrane);GO:0099175(regulation of postsynapse organization)","04514(Cell adhesion molecules (CAMs))","K06756","NA","neuronal cell adhesion molecule [Source:HGNC Symbol;Acc:HGNC:7994]",{"v":2.947521,"d":"2.95"},{"v":2.893904,"d":"2.89"},{"v":2.688344,"d":"2.69"},0,0,0,"inf","inf",{"v":1.29028851457258e-14,"d":"0.00"},{"v":1.56253939114739e-10,"d":"0.00"},"up","yes"]
[158770,0,"chr5","-",43527093,43557695,"ENST00000338972",11,1814,"ENSG00000172239","PAIP1","GO:0003723(RNA binding);GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0006413(translational initiation);GO:0006417(regulation of translation);GO:0006446(regulation of translational initiation);GO:0008494(translation activator activity);GO:0045727(positive regulation of translation);GO:0048255(mRNA stabilization)","03013(RNA transport)","K14322","NA","poly(A) binding protein interacting protein 1 [Source:HGNC Symbol;Acc:HGNC:16945]",{"v":0.022738,"d":"0.02"},{"v":0.02426,"d":"0.02"},0,{"v":10.356412,"d":"10.36"},{"v":28.178709,"d":"28.18"},{"v":13.791718,"d":"13.79"},{"v":0.000898162413364965,"d":"0.00"},{"v":-10.1207360306079,"d":"-10.12"},{"v":3.97162221049301e-14,"d":"0.00"},{"v":2.9222470191461e-10,"d":"0.00"},"down","yes"]
[72978,0,"chr16","+",27341289,27364777,"ENST00000170630",9,3380,"ENSG00000077238","IL4R","GO:0002376(immune system process);GO:0002532(production of molecular mediator involved in inflammatory response);GO:0002639(positive regulation of immunoglobulin production);GO:0004896(cytokine receptor activity);GO:0004913(interleukin-4 receptor activity);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0005615(extracellular space);GO:0005886(plasma membrane);GO:0005887(integral component of plasma membrane);GO:0006955(immune response);GO:0007165(signal transduction);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016064(immunoglobulin mediated immune response);GO:0019221(cytokine-mediated signaling pathway);GO:0030728(ovulation);GO:0035771(interleukin-4-mediated signaling pathway);GO:0042127(regulation of cell population proliferation);GO:0042832(defense response to protozoan);GO:0043032(positive regulation of macrophage activation);GO:0043235(receptor complex);GO:0043306(positive regulation of mast cell degranulation);GO:0043627(response to estrogen);GO:0045626(negative regulation of T-helper 1 cell differentiation);GO:0045630(positive regulation of T-helper 2 cell differentiation);GO:0090197(positive regulation of chemokine secretion);GO:0120162(positive regulation of cold-induced thermogenesis);GO:1901741(positive regulation of myoblast fusion);GO:1990834(response to odorant)","04060(Cytokine-cytokine receptor interaction);04151(PI3K-Akt signaling pathway);04630(Jak-STAT signaling pathway);04640(Hematopoietic cell lineage);04658(Th1 and Th2 cell differentiation);04659(Th17 cell differentiation);05200(Pathways in cancer);05321(Inflammatory bowel disease (IBD))","K05071","NA","interleukin 4 receptor [Source:HGNC Symbol;Acc:HGNC:6015]",{"v":4.426486,"d":"4.43"},{"v":6.166371,"d":"6.17"},{"v":4.362369,"d":"4.36"},0,0,0,"inf","inf",{"v":4.02180982541439e-14,"d":"0.00"},{"v":2.9222470191461e-10,"d":"0.00"},"up","yes"]
[173122,0,"chr6","+",110982050,111028263,"ENST00000607388",9,3621,"ENSG00000197498","RPF2","GO:0000027(ribosomal large subunit assembly);GO:0000463(maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA));GO:0000470(maturation of LSU-rRNA);GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005730(nucleolus);GO:0008097(5S rRNA binding);GO:0019843(rRNA binding);GO:0042254(ribosome biogenesis);GO:0042273(ribosomal large subunit biogenesis);GO:1901796(regulation of signal transduction by p53 class mediator);GO:1902570(protein localization to nucleolus)","NA","K14847","NA","ribosome production factor 2 homolog [Source:HGNC Symbol;Acc:HGNC:20870]",{"v":3.790668,"d":"3.79"},{"v":3.776484,"d":"3.78"},{"v":4.625769,"d":"4.63"},0,0,0,"inf","inf",{"v":2.22387033772347e-13,"d":"0.00"},{"v":1.34655348949156e-9,"d":"0.00"},"up","yes"]
[52110,0,"chr13","-",52412602,52450244,"ENST00000611132",14,4607,"ENSG00000136100","VPS36","GO:0000814(ESCRT II complex);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005764(lysosome);GO:0005768(endosome);GO:0005770(late endosome);GO:0005829(cytosol);GO:0008022(protein C-terminus binding);GO:0008289(lipid binding);GO:0015031(protein transport);GO:0016020(membrane);GO:0016197(endosomal transport);GO:0016236(macroautophagy);GO:0031902(late endosome membrane);GO:0032266(phosphatidylinositol-3-phosphate binding);GO:0032509(endosome transport via multivesicular body sorting pathway);GO:0036258(multivesicular body assembly);GO:0043130(ubiquitin binding);GO:0043328(protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway);GO:0070062(extracellular exosome)","04144(Endocytosis)","K12190","NA","vacuolar protein sorting 36 homolog [Source:HGNC Symbol;Acc:HGNC:20312]",{"v":0.014359,"d":"0.01"},0,{"v":0.022376,"d":"0.02"},{"v":8.770304,"d":"8.77"},{"v":6.277677,"d":"6.28"},{"v":6.903057,"d":"6.90"},{"v":0.0016734971712955,"d":"0.00"},{"v":-9.22291817221632,"d":"-9.22"},{"v":2.61082447723341e-13,"d":"0.00"},{"v":1.35501790368414e-9,"d":"0.00"},"down","yes"]
[88610,0,"chr17","+",60679458,61392831,"ENST00000408905",24,3514,"ENSG00000141376","BCAS3","GO:0001525(angiogenesis);GO:0003682(chromatin binding);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005730(nucleolus);GO:0005737(cytoplasm);GO:0005856(cytoskeleton);GO:0005881(cytoplasmic microtubule);GO:0007030(Golgi organization);GO:0008134(transcription factor binding);GO:0010595(positive regulation of endothelial cell migration);GO:0010698(acetyltransferase activator activity);GO:0031023(microtubule organizing center organization);GO:0031252(cell leading edge);GO:0034260(negative regulation of GTPase activity);GO:0035035(histone acetyltransferase binding);GO:0035148(tube formation);GO:0035257(nuclear hormone receptor binding);GO:0035327(transcriptionally active chromatin);GO:0042393(histone binding);GO:0042594(response to starvation);GO:0043085(positive regulation of catalytic activity);GO:0043547(positive regulation of GTPase activity);GO:0045111(intermediate filament cytoskeleton);GO:0045944(positive regulation of transcription by RNA polymerase II);GO:0048487(beta-tubulin binding);GO:0051491(positive regulation of filopodium assembly);GO:0051895(negative regulation of focal adhesion assembly);GO:0071391(cellular response to estrogen stimulus);GO:0071944(cell periphery);GO:0090316(positive regulation of intracellular protein transport);GO:0090630(activation of GTPase activity);GO:2000114(regulation of establishment of cell polarity);GO:2000251(positive regulation of actin cytoskeleton reorganization)","NA","NA","NA","BCAS3, microtubule associated cell migration factor [Source:HGNC Symbol;Acc:HGNC:14347]",0,0,0,{"v":3.596637,"d":"3.60"},{"v":5.04855,"d":"5.05"},{"v":3.439396,"d":"3.44"},"-inf","-inf",{"v":3.42648221735134e-13,"d":"0.00"},{"v":1.55605123695468e-9,"d":"0.00"},"down","yes"]
[180075,0,"chr7","+",74657685,74760692,"ENST00000573035",35,4548,"ENSG00000263001","GTF2I","GO:0003677(DNA binding);GO:0003700(DNA-binding transcription factor activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0006355(regulation of transcription, DNA-templated);GO:0006366(transcription by RNA polymerase II);GO:0006367(transcription initiation from RNA polymerase II promoter);GO:0007165(signal transduction);GO:0016020(membrane);GO:0016525(negative regulation of angiogenesis);GO:0051481(negative regulation of cytosolic calcium ion concentration)","03022(Basal transcription factors);04022(cGMP-PKG signaling pathway)","K03121","NA","general transcription factor IIi [Source:HGNC Symbol;Acc:HGNC:4659]",{"v":10.447186,"d":"10.45"},{"v":6.312899,"d":"6.31"},{"v":9.036822,"d":"9.04"},{"v":0.021998,"d":"0.02"},0,0,{"v":1172.69329029912,"d":"1172.69"},{"v":10.1956100205994,"d":"10.20"},{"v":1.00561772474127e-12,"d":"0.00"},{"v":4.05934354887227e-9,"d":"0.00"},"up","yes"]
[14463,0,"chr1","+",180632032,180886126,"ENST00000367589",14,4126,"ENSG00000143324","XPR1","GO:0000822(inositol hexakisphosphate binding);GO:0001618(virus receptor activity);GO:0004888(transmembrane signaling receptor activity);GO:0004930(G protein-coupled receptor activity);GO:0005794(Golgi apparatus);GO:0005886(plasma membrane);GO:0007186(G protein-coupled receptor signaling pathway);GO:0009615(response to virus);GO:0015114(phosphate ion transmembrane transporter activity);GO:0015562(efflux transmembrane transporter activity);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0030643(cellular phosphate ion homeostasis);GO:0031226(intrinsic component of plasma membrane);GO:0035435(phosphate ion transmembrane transport);GO:0038023(signaling receptor activity);GO:0046718(viral entry into host cell)","NA","NA","NA","xenotropic and polytropic retrovirus receptor 1 [Source:HGNC Symbol;Acc:HGNC:12827]",0,0,0,{"v":2.807855,"d":"2.81"},{"v":1.465982,"d":"1.47"},{"v":4.7371,"d":"4.74"},"-inf","-inf",{"v":4.25709370175831e-12,"d":"0.00"},{"v":1.54660214184879e-8,"d":"0.00"},"down","yes"]
[53109,0,"chr13","-",101053776,101416508,"ENST00000251127",44,6971,"ENSG00000102452","NALCN","GO:0005216(ion channel activity);GO:0005244(voltage-gated ion channel activity);GO:0005261(cation channel activity);GO:0005272(sodium channel activity);GO:0005515(protein binding);GO:0005886(plasma membrane);GO:0006811(ion transport);GO:0006814(sodium ion transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0022840(leak channel activity);GO:0034220(ion transmembrane transport);GO:0034765(regulation of ion transmembrane transport);GO:0035725(sodium ion transmembrane transport);GO:0055085(transmembrane transport);GO:0060075(regulation of resting membrane potential);GO:0070588(calcium ion transmembrane transport);GO:0071805(potassium ion transmembrane transport);GO:0098655(cation transmembrane transport)","NA","K21863","NA","sodium leak channel, non-selective [Source:HGNC Symbol;Acc:HGNC:19082]",0,0,0,{"v":1.169674,"d":"1.17"},{"v":1.733809,"d":"1.73"},{"v":1.613573,"d":"1.61"},"-inf","-inf",{"v":5.11649659631067e-12,"d":"0.00"},{"v":1.66172333887971e-8,"d":"0.00"},"down","yes"]
[7701,0,"chr1","+",78303884,78539749,"ENST00000370758",4,4337,"ENSG00000122420","PTGFR","GO:0004930(G protein-coupled receptor activity);GO:0004958(prostaglandin F receptor activity);GO:0005576(extracellular region);GO:0005737(cytoplasm);GO:0005886(plasma membrane);GO:0005887(integral component of plasma membrane);GO:0006954(inflammatory response);GO:0007165(signal transduction);GO:0007186(G protein-coupled receptor signaling pathway);GO:0007189(adenylate cyclase-activating G protein-coupled receptor signaling pathway);GO:0007204(positive regulation of cytosolic calcium ion concentration);GO:0007567(parturition);GO:0008284(positive regulation of cell population proliferation);GO:0010628(positive regulation of gene expression);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0032355(response to estradiol);GO:0032496(response to lipopolysaccharide);GO:0035584(calcium-mediated signaling using intracellular calcium source);GO:0043066(negative regulation of apoptotic process);GO:0071799(cellular response to prostaglandin D stimulus)","04020(Calcium signaling pathway);04072(Phospholipase D signaling pathway);04080(Neuroactive ligand-receptor interaction)","NA","NA","prostaglandin F receptor [Source:HGNC Symbol;Acc:HGNC:9600]",{"v":1.01802,"d":"1.02"},{"v":3.48518,"d":"3.49"},{"v":5.864369,"d":"5.86"},0,0,0,"inf","inf",{"v":5.48876412511878e-12,"d":"0.00"},{"v":1.66172333887971e-8,"d":"0.00"},"up","yes"]
[34568,0,"chr11","-",77616195,77637751,"ENST00000263309",6,1172,"ENSG00000074201","CLNS1A","GO:0000387(spliceosomal snRNP assembly);GO:0003723(RNA binding);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005856(cytoskeleton);GO:0005886(plasma membrane);GO:0006821(chloride transport);GO:0006884(cell volume homeostasis);GO:0034709(methylosome);GO:0034715(pICln-Sm protein complex);GO:0046982(protein heterodimerization activity)","03013(RNA transport)","NA","NA","chloride nucleotide-sensitive channel 1A [Source:HGNC Symbol;Acc:HGNC:2080]",0,0,0,{"v":6.42245,"d":"6.42"},{"v":9.029629,"d":"9.03"},{"v":7.940492,"d":"7.94"},"-inf","-inf",{"v":1.2022842583754e-11,"d":"0.00"},{"v":3.35992208513678e-8,"d":"0.00"},"down","yes"]
[42488,0,"chr12","-",49185010,49186864,"ENST00000550767",3,1384,"ENSG00000167552","TUBA1A","GO:0000086(G2/M transition of mitotic cell cycle);GO:0000166(nucleotide binding);GO:0000226(microtubule cytoskeleton organization);GO:0000278(mitotic cell cycle);GO:0003924(GTPase activity);GO:0005198(structural molecule activity);GO:0005200(structural constituent of cytoskeleton);GO:0005515(protein binding);GO:0005525(GTP binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005856(cytoskeleton);GO:0005874(microtubule);GO:0005881(cytoplasmic microtubule);GO:0007010(cytoskeleton organization);GO:0007017(microtubule-based process);GO:0010389(regulation of G2/M transition of mitotic cell cycle);GO:0015630(microtubule cytoskeleton);GO:0019904(protein domain specific binding);GO:0030705(cytoskeleton-dependent intracellular transport);GO:0031594(neuromuscular junction);GO:0036464(cytoplasmic ribonucleoprotein granule);GO:0043209(myelin sheath);GO:0045121(membrane raft);GO:0050807(regulation of synapse organization);GO:0051301(cell division);GO:0055037(recycling endosome);GO:0070062(extracellular exosome);GO:0097711(ciliary basal body-plasma membrane docking)","04145(Phagosome);04210(Apoptosis);04530(Tight junction);04540(Gap junction);05130(Pathogenic Escherichia coli infection)","K07374","NA","tubulin alpha 1a [Source:HGNC Symbol;Acc:HGNC:20766]",{"v":0.564324,"d":"0.56"},{"v":1.140152,"d":"1.14"},{"v":0.63097,"d":"0.63"},{"v":93.467506,"d":"93.47"},{"v":30.729448,"d":"30.73"},{"v":42.930016,"d":"42.93"},{"v":0.013974082100573,"d":"0.01"},{"v":-6.16110266824062,"d":"-6.16"},{"v":2.26459405934264e-11,"d":"0.00"},{"v":5.87662158399416e-8,"d":"0.00"},"down","yes"]
[7153,0,"chr1","+",66332004,66374579,"ENST00000371045",10,3982,"ENSG00000184588","PDE4B","GO:0000930(gamma-tubulin complex);GO:0001780(neutrophil homeostasis);GO:0004114(3',5'-cyclic-nucleotide phosphodiesterase activity);GO:0004115(3',5'-cyclic-AMP phosphodiesterase activity);GO:0005515(protein binding);GO:0005813(centrosome);GO:0005829(cytosol);GO:0005891(voltage-gated calcium channel complex);GO:0006198(cAMP catabolic process);GO:0007165(signal transduction);GO:0007186(G protein-coupled receptor signaling pathway);GO:0008021(synaptic vesicle);GO:0008081(phosphoric diester hydrolase activity);GO:0014069(postsynaptic density);GO:0016020(membrane);GO:0016787(hydrolase activity);GO:0030018(Z disc);GO:0030552(cAMP binding);GO:0030593(neutrophil chemotaxis);GO:0032729(positive regulation of interferon-gamma production);GO:0032743(positive regulation of interleukin-2 production);GO:0035690(cellular response to drug);GO:0043015(gamma-tubulin binding);GO:0043197(dendritic spine);GO:0044325(ion channel binding);GO:0046872(metal ion binding);GO:0050852(T cell receptor signaling pathway);GO:0050900(leukocyte migration);GO:0060076(excitatory synapse);GO:0071222(cellular response to lipopolysaccharide);GO:0071872(cellular response to epinephrine stimulus);GO:0071944(cell periphery);GO:0086004(regulation of cardiac muscle cell contraction);GO:1901841(regulation of high voltage-gated calcium channel activity);GO:1901898(negative regulation of relaxation of cardiac muscle)","00230(Purine metabolism);04024(cAMP signaling pathway);04928(Parathyroid hormone synthesis, secretion and action);05032(Morphine addiction)","NA","NA","phosphodiesterase 4B [Source:HGNC Symbol;Acc:HGNC:8781]",{"v":1.516115,"d":"1.52"},{"v":1.722586,"d":"1.72"},{"v":1.613591,"d":"1.61"},0,0,0,"inf","inf",{"v":2.11072990828269e-10,"d":"0.00"},{"v":5.11218783786067e-7,"d":"0.00"},"up","yes"]
[157464,0,"chr5","+",7869104,7901124,"ENST00000264668",15,3274,"ENSG00000124275","MTRR","GO:0000096(sulfur amino acid metabolic process);GO:0003958(NADPH-hemoprotein reductase activity);GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0006306(DNA methylation);GO:0006555(methionine metabolic process);GO:0008652(cellular amino acid biosynthetic process);GO:0009086(methionine biosynthetic process);GO:0009235(cobalamin metabolic process);GO:0010181(FMN binding);GO:0016491(oxidoreductase activity);GO:0016723(oxidoreductase activity, oxidizing metal ions, NAD or NADP as acceptor);GO:0030586([methionine synthase] reductase activity);GO:0032259(methylation);GO:0033353(S-adenosylmethionine cycle);GO:0043418(homocysteine catabolic process);GO:0046655(folic acid metabolic process);GO:0050444(aquacobalamin reductase (NADPH) activity);GO:0050660(flavin adenine dinucleotide binding);GO:0050661(NADP binding);GO:0050667(homocysteine metabolic process);GO:0055114(oxidation-reduction process);GO:0070402(NADPH binding);GO:0071949(FAD binding);GO:1904042(negative regulation of cystathionine beta-synthase activity)","NA","K00597","EC:1.16.1.8","5-methyltetrahydrofolate-homocysteine methyltransferase reductase [Source:HGNC Symbol;Acc:HGNC:7473]",{"v":1.899282,"d":"1.90"},{"v":2.105129,"d":"2.11"},{"v":1.734965,"d":"1.73"},0,0,0,"inf","inf",{"v":2.64850157207878e-10,"d":"0.00"},{"v":6.01375388210139e-7,"d":"0.00"},"up","yes"]
[79659,0,"chr17","+",1716523,1738599,"ENST00000437219",10,3184,"ENSG00000167716","WDR81","GO:0000421(autophagosome membrane);GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0005739(mitochondrion);GO:0005764(lysosome);GO:0005765(lysosomal membrane);GO:0005768(endosome);GO:0005829(cytosol);GO:0006511(ubiquitin-dependent protein catabolic process);GO:0007005(mitochondrion organization);GO:0010923(negative regulation of phosphatase activity);GO:0016020(membrane);GO:0031313(extrinsic component of endosome membrane);GO:0031410(cytoplasmic vesicle);GO:0031901(early endosome membrane);GO:0031902(late endosome membrane);GO:0035014(phosphatidylinositol 3-kinase regulator activity);GO:0035973(aggrephagy);GO:0043551(regulation of phosphatidylinositol 3-kinase activity);GO:0045022(early endosome to late endosome transport);GO:0050821(protein stabilization);GO:0070530(K63-linked polyubiquitin modification-dependent protein binding)","NA","K17601","NA","WD repeat domain 81 [Source:HGNC Symbol;Acc:HGNC:26600]",{"v":1.18657,"d":"1.19"},{"v":2.909112,"d":"2.91"},{"v":2.273805,"d":"2.27"},0,0,0,"inf","inf",{"v":2.99386197964246e-10,"d":"0.00"},{"v":6.39805916002416e-7,"d":"0.00"},"up","yes"]
[120779,0,"chr2","+",200812356,200822243,"ENST00000452790",12,1473,"ENSG00000082153","BZW1","GO:0003723(RNA binding);GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0045296(cadherin binding)","NA","NA","NA","basic leucine zipper and W2 domains 1 [Source:HGNC Symbol;Acc:HGNC:18380]",{"v":2.476089,"d":"2.48"},{"v":4.537007,"d":"4.54"},{"v":4.766867,"d":"4.77"},0,0,0,"inf","inf",{"v":5.92712627381354e-10,"d":"0.00"},{"v":1.19629165293137e-6,"d":"0.00"},"up","yes"]
[138787,0,"chr3","-",42547969,42563632,"ENST00000451653",5,5955,"ENSG00000093183","SEC22C","GO:0005515(protein binding);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0006888(endoplasmic reticulum to Golgi vesicle-mediated transport);GO:0015031(protein transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016192(vesicle-mediated transport)","NA","K08520","NA","SEC22 homolog C, vesicle trafficking protein [Source:HGNC Symbol;Acc:HGNC:16828]",{"v":0.055233,"d":"0.06"},{"v":0.004897,"d":"0.00"},{"v":0.053563,"d":"0.05"},{"v":4.957563,"d":"4.96"},{"v":5.333902,"d":"5.33"},{"v":5.055829,"d":"5.06"},{"v":0.0074080160320119,"d":"0.01"},{"v":-7.07669706386104,"d":"-7.08"},{"v":7.4036443622114e-10,"d":"0.00"},{"v":1.38357471181101e-6,"d":"0.00"},"down","yes"]
[53110,0,"chr13","-",101053797,101416474,"ENST00000648359",45,7105,"ENSG00000102452","NALCN","GO:0005216(ion channel activity);GO:0005244(voltage-gated ion channel activity);GO:0005261(cation channel activity);GO:0005272(sodium channel activity);GO:0005515(protein binding);GO:0005886(plasma membrane);GO:0006811(ion transport);GO:0006814(sodium ion transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0022840(leak channel activity);GO:0034220(ion transmembrane transport);GO:0034765(regulation of ion transmembrane transport);GO:0035725(sodium ion transmembrane transport);GO:0055085(transmembrane transport);GO:0060075(regulation of resting membrane potential);GO:0070588(calcium ion transmembrane transport);GO:0071805(potassium ion transmembrane transport);GO:0098655(cation transmembrane transport)","NA","K21863","NA","sodium leak channel, non-selective [Source:HGNC Symbol;Acc:HGNC:19082]",{"v":0.628943,"d":"0.63"},{"v":0.933163,"d":"0.93"},{"v":0.663129,"d":"0.66"},0,0,0,"inf","inf",{"v":7.6167063683513e-10,"d":"0.00"},{"v":1.38357471181101e-6,"d":"0.00"},"up","yes"]
[44397,0,"chr12","-",56417119,56449403,"ENST00000229201",29,4376,"ENSG00000111602","TIMELESS","GO:0000076(DNA replication checkpoint);GO:0000122(negative regulation of transcription by RNA polymerase II);GO:0000790(nuclear chromatin);GO:0002009(morphogenesis of an epithelium);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005694(chromosome);GO:0006260(DNA replication);GO:0006281(DNA repair);GO:0006974(cellular response to DNA damage stimulus);GO:0007049(cell cycle);GO:0007275(multicellular organism development);GO:0007623(circadian rhythm);GO:0009582(detection of abiotic stimulus);GO:0030324(lung development);GO:0031298(replication fork protection complex);GO:0035861(site of double-strand break);GO:0042752(regulation of circadian rhythm);GO:0042803(protein homodimerization activity);GO:0043111(replication fork arrest);GO:0044770(cell cycle phase transition);GO:0045892(negative regulation of transcription, DNA-templated);GO:0046982(protein heterodimerization activity);GO:0048478(replication fork protection);GO:0048511(rhythmic process);GO:0048754(branching morphogenesis of an epithelial tube);GO:0051301(cell division);GO:0072711(cellular response to hydroxyurea);GO:0072719(cellular response to cisplatin);GO:1904976(cellular response to bleomycin);GO:1905168(positive regulation of double-strand break repair via homologous recombination);GO:2000781(positive regulation of double-strand break repair)","NA","K03155","NA","timeless circadian regulator [Source:HGNC Symbol;Acc:HGNC:11813]",{"v":1.269084,"d":"1.27"},{"v":1.111724,"d":"1.11"},{"v":1.035283,"d":"1.04"},0,0,0,"inf","inf",{"v":9.32862930761442e-10,"d":"0.00"},{"v":1.61385287021729e-6,"d":"0.00"},"up","yes"]
[66183,0,"chr15","+",73051710,73305205,"ENST00000339362",30,7342,"ENSG00000067141","NEO1","GO:0005515(protein binding);GO:0005654(nucleoplasm);GO:0005794(Golgi apparatus);GO:0005886(plasma membrane);GO:0005887(integral component of plasma membrane);GO:0007155(cell adhesion);GO:0007399(nervous system development);GO:0007411(axon guidance);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0030513(positive regulation of BMP signaling pathway);GO:0038023(signaling receptor activity);GO:0039706(co-receptor binding);GO:0055072(iron ion homeostasis);GO:0098797(plasma membrane protein complex)","04350(TGF-beta signaling pathway);04360(Axon guidance);04514(Cell adhesion molecules (CAMs))","K06766","NA","neogenin 1 [Source:HGNC Symbol;Acc:HGNC:7754]",0,{"v":0.004783,"d":"0.00"},0,{"v":0.62565,"d":"0.63"},{"v":2.729733,"d":"2.73"},{"v":3.390226,"d":"3.39"},{"v":0.000709053845249554,"d":"0.00"},{"v":-10.4618171902725,"d":"-10.46"},{"v":1.01728861283577e-9,"d":"0.00"},{"v":1.62592015670151e-6,"d":"0.00"},"down","yes"]
[113086,0,"chr2","-",65086855,65130105,"ENST00000409892",4,2254,"ENSG00000138069","RAB1A","GO:0000045(autophagosome assembly);GO:0000139(Golgi membrane);GO:0000166(nucleotide binding);GO:0003924(GTPase activity);GO:0005515(protein binding);GO:0005525(GTP binding);GO:0005737(cytoplasm);GO:0005768(endosome);GO:0005769(early endosome);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005794(Golgi apparatus);GO:0005829(cytosol);GO:0006886(intracellular protein transport);GO:0006888(endoplasmic reticulum to Golgi vesicle-mediated transport);GO:0006890(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum);GO:0006897(endocytosis);GO:0006914(autophagy);GO:0007030(Golgi organization);GO:0015031(protein transport);GO:0016020(membrane);GO:0016192(vesicle-mediated transport);GO:0016477(cell migration);GO:0019068(virion assembly);GO:0030252(growth hormone secretion);GO:0030658(transport vesicle membrane);GO:0032402(melanosome transport);GO:0032482(Rab protein signal transduction);GO:0034446(substrate adhesion-dependent cell spreading);GO:0042470(melanosome);GO:0042742(defense response to bacterium);GO:0043687(post-translational protein modification);GO:0045296(cadherin binding);GO:0047496(vesicle transport along microtubule);GO:0048208(COPII vesicle coating);GO:0070062(extracellular exosome);GO:0072606(interleukin-8 secretion);GO:0090110(COPII-coated vesicle cargo loading);GO:1903020(positive regulation of glycoprotein metabolic process);GO:1904668(positive regulation of ubiquitin protein ligase activity)","05134(Legionellosis)","K07874","NA","RAB1A, member RAS oncogene family [Source:HGNC Symbol;Acc:HGNC:9758]",{"v":5.660459,"d":"5.66"},{"v":0.668508,"d":"0.67"},{"v":5.283782,"d":"5.28"},0,0,0,"inf","inf",{"v":1.02934664476011e-9,"d":"0.00"},{"v":1.62592015670151e-6,"d":"0.00"},"up","yes"]
[146432,0,"chr3","+",170357734,170392947,"ENST00000426052",8,2757,"ENSG00000136603","SKIL","GO:0000122(negative regulation of transcription by RNA polymerase II);GO:0000978(RNA polymerase II proximal promoter sequence-specific DNA binding);GO:0000981(DNA-binding transcription factor activity, RNA polymerase II-specific);GO:0001227(DNA-binding transcription repressor activity, RNA polymerase II-specific);GO:0001669(acrosomal vesicle);GO:0001825(blastocyst formation);GO:0002260(lymphocyte homeostasis);GO:0003682(chromatin binding);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0007050(cell cycle arrest);GO:0007179(transforming growth factor beta receptor signaling pathway);GO:0007283(spermatogenesis);GO:0030512(negative regulation of transforming growth factor beta receptor signaling pathway);GO:0030514(negative regulation of BMP signaling pathway);GO:0032991(protein-containing complex);GO:0034097(response to cytokine);GO:0045596(negative regulation of cell differentiation);GO:0046332(SMAD binding);GO:0048666(neuron development);GO:0050772(positive regulation of axonogenesis);GO:0070306(lens fiber cell differentiation);GO:1902043(positive regulation of extrinsic apoptotic signaling pathway via death domain receptors);GO:1902231(positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage)","04550(Signaling pathways regulating pluripotency of stem cells)","NA","NA","SKI like proto-oncogene [Source:HGNC Symbol;Acc:HGNC:10897]",{"v":1.974384,"d":"1.97"},{"v":2.063232,"d":"2.06"},{"v":1.280208,"d":"1.28"},0,0,0,"inf","inf",{"v":1.22270949130536e-9,"d":"0.00"},{"v":1.85087649246349e-6,"d":"0.00"},"up","yes"]
[171710,0,"chr6","-",69676108,69796341,"ENST00000650043",16,1652,"ENSG00000168216","LMBRD1","GO:0005158(insulin receptor binding);GO:0005764(lysosome);GO:0005765(lysosomal membrane);GO:0005886(plasma membrane);GO:0009235(cobalamin metabolic process);GO:0015420(cobalamin-transporting ATPase activity);GO:0015889(cobalamin transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016032(viral process);GO:0031419(cobalamin binding);GO:0045334(clathrin-coated endocytic vesicle)","04977(Vitamin digestion and absorption)","K14617","NA","LMBR1 domain containing 1 [Source:HGNC Symbol;Acc:HGNC:23038]",0,0,0,{"v":2.546158,"d":"2.55"},{"v":3.908959,"d":"3.91"},{"v":2.043806,"d":"2.04"},"-inf","-inf",{"v":1.41939254965418e-9,"d":"0.00"},{"v":2.06266125315746e-6,"d":"0.00"},"down","yes"]
[40562,0,"chr12","+",15897945,15903340,"ENST00000538718",3,648,"ENSG00000023734","STRAP","GO:0000122(negative regulation of transcription by RNA polymerase II);GO:0000387(spliceosomal snRNP assembly);GO:0003723(RNA binding);GO:0005102(signaling receptor binding);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0006397(mRNA processing);GO:0008380(RNA splicing);GO:0010633(negative regulation of epithelial cell migration);GO:0010719(negative regulation of epithelial to mesenchymal transition);GO:0030277(maintenance of gastrointestinal epithelium);GO:0030512(negative regulation of transforming growth factor beta receptor signaling pathway);GO:0032797(SMN complex);GO:0034719(SMN-Sm protein complex);GO:0050680(negative regulation of epithelial cell proliferation);GO:0060394(negative regulation of pathway-restricted SMAD protein phosphorylation)","03013(RNA transport)","K13137","NA","serine/threonine kinase receptor associated protein [Source:HGNC Symbol;Acc:HGNC:30796]",0,0,0,{"v":6.563406,"d":"6.56"},{"v":5.437682,"d":"5.44"},{"v":5.872635,"d":"5.87"},"-inf","-inf",{"v":1.66504158840484e-9,"d":"0.00"},{"v":2.31468673763844e-6,"d":"0.00"},"down","yes"]
[133766,0,"chr22","-",31439373,31488745,"ENST00000397523",17,3420,"ENSG00000184708","EIF4ENIF1","GO:0000932(P-body);GO:0003723(RNA binding);GO:0003729(mRNA binding);GO:0003743(translation initiation factor activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0006413(translational initiation);GO:0008565(protein transporter activity);GO:0015031(protein transport);GO:0016020(membrane);GO:0016605(PML body);GO:0016607(nuclear speck);GO:0017148(negative regulation of translation);GO:0019827(stem cell population maintenance);GO:0043231(intracellular membrane-bounded organelle);GO:0045665(negative regulation of neuron differentiation)","NA","K18728","NA","eukaryotic translation initiation factor 4E nuclear import factor 1 [Source:HGNC Symbol;Acc:HGNC:16687]",{"v":0.393453,"d":"0.39"},{"v":3.180404,"d":"3.18"},{"v":3.473806,"d":"3.47"},0,0,0,"inf","inf",{"v":1.72024613036713e-9,"d":"0.00"},{"v":2.31468673763844e-6,"d":"0.00"},"up","yes"]
[141050,0,"chr3","-",56727421,56775657,"ENST00000413728",10,3992,"ENSG00000163947","ARHGEF3","GO:0005085(guanyl-nucleotide exchange factor activity);GO:0005089(Rho guanyl-nucleotide exchange factor activity);GO:0005515(protein binding);GO:0005622(intracellular);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0007186(G protein-coupled receptor signaling pathway);GO:0007266(Rho protein signal transduction);GO:0035023(regulation of Rho protein signal transduction);GO:0035556(intracellular signal transduction);GO:0043065(positive regulation of apoptotic process);GO:0051056(regulation of small GTPase mediated signal transduction)","NA","K20683","NA","Rho guanine nucleotide exchange factor 3 [Source:HGNC Symbol;Acc:HGNC:683]",0,0,0,{"v":1.064053,"d":"1.06"},{"v":0.830611,"d":"0.83"},{"v":0.871599,"d":"0.87"},"-inf","-inf",{"v":2.10758203365842e-9,"d":"0.00"},{"v":2.7345876886718e-6,"d":"0.00"},"down","yes"]
[119394,0,"chr2","-",174432238,174487080,"ENST00000392552",16,6730,"ENSG00000163328","GPR155","GO:0003674(molecular_function);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0035556(intracellular signal transduction);GO:0050890(cognition);GO:0055085(transmembrane transport);GO:0070062(extracellular exosome)","NA","NA","NA","G protein-coupled receptor 155 [Source:HGNC Symbol;Acc:HGNC:22951]",{"v":0.907135,"d":"0.91"},{"v":0.423122,"d":"0.42"},{"v":0.617312,"d":"0.62"},0,0,0,"inf","inf",{"v":2.19081690930874e-9,"d":"0.00"},{"v":2.74456476948918e-6,"d":"0.00"},"up","yes"]
[35517,0,"chr11","+",95790522,95818903,"ENST00000541365",6,870,"ENSG00000166037","CEP57","GO:0000086(G2/M transition of mitotic cell cycle);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005794(Golgi apparatus);GO:0005813(centrosome);GO:0005815(microtubule organizing center);GO:0005829(cytosol);GO:0005856(cytoskeleton);GO:0005874(microtubule);GO:0007286(spermatid development);GO:0008017(microtubule binding);GO:0008543(fibroblast growth factor receptor signaling pathway);GO:0010389(regulation of G2/M transition of mitotic cell cycle);GO:0017134(fibroblast growth factor binding);GO:0034453(microtubule anchoring);GO:0042802(identical protein binding);GO:0042803(protein homodimerization activity);GO:0043015(gamma-tubulin binding);GO:0051260(protein homooligomerization);GO:0097711(ciliary basal body-plasma membrane docking)","NA","K16762","NA","centrosomal protein 57 [Source:HGNC Symbol;Acc:HGNC:30794]",0,0,0,{"v":3.701033,"d":"3.70"},{"v":4.022194,"d":"4.02"},{"v":3.686523,"d":"3.69"},"-inf","-inf",{"v":2.74601961365655e-9,"d":"0.00"},{"v":3.13653390453673e-6,"d":"0.00"},"down","yes"]
[63965,0,"chr15","+",47718489,47774223,"ENST00000354744",18,5931,"ENSG00000137872","SEMA6D","GO:0001755(neural crest cell migration);GO:0005515(protein binding);GO:0005615(extracellular space);GO:0005737(cytoplasm);GO:0005794(Golgi apparatus);GO:0005886(plasma membrane);GO:0005887(integral component of plasma membrane);GO:0007275(multicellular organism development);GO:0007399(nervous system development);GO:0014911(positive regulation of smooth muscle cell migration);GO:0014912(negative regulation of smooth muscle cell migration);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0021591(ventricular system development);GO:0030154(cell differentiation);GO:0030215(semaphorin receptor binding);GO:0030335(positive regulation of cell migration);GO:0038191(neuropilin binding);GO:0045499(chemorepellent activity);GO:0048843(negative regulation of axon extension involved in axon guidance);GO:0050919(negative chemotaxis);GO:0071526(semaphorin-plexin signaling pathway)","04360(Axon guidance)","K06842","NA","semaphorin 6D [Source:HGNC Symbol;Acc:HGNC:16770]",{"v":1.192408,"d":"1.19"},{"v":0.725881,"d":"0.73"},{"v":0.410128,"d":"0.41"},0,0,0,"inf","inf",{"v":2.74922217664275e-9,"d":"0.00"},{"v":3.13653390453673e-6,"d":"0.00"},"up","yes"]
[68140,0,"chr15","-",90083996,90102468,"ENST00000560061",9,1449,"ENSG00000182054","IDH2","GO:0000287(magnesium ion binding);GO:0004448(isocitrate dehydrogenase activity);GO:0004450(isocitrate dehydrogenase (NADP+) activity);GO:0005739(mitochondrion);GO:0005759(mitochondrial matrix);GO:0005777(peroxisome);GO:0005829(cytosol);GO:0005975(carbohydrate metabolic process);GO:0006097(glyoxylate cycle);GO:0006099(tricarboxylic acid cycle);GO:0006102(isocitrate metabolic process);GO:0006103(2-oxoglutarate metabolic process);GO:0006739(NADP metabolic process);GO:0006741(NADP biosynthetic process);GO:0016491(oxidoreductase activity);GO:0016616(oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor);GO:0042803(protein homodimerization activity);GO:0046872(metal ion binding);GO:0051287(NAD binding);GO:0055114(oxidation-reduction process);GO:0060253(negative regulation of glial cell proliferation);GO:0070062(extracellular exosome);GO:1903976(negative regulation of glial cell migration);GO:1904465(negative regulation of matrix metallopeptidase secretion)","00020(Citrate cycle (TCA cycle));00480(Glutathione metabolism);04146(Peroxisome)","NA","NA","isocitrate dehydrogenase (NADP(+)) 2, mitochondrial [Source:HGNC Symbol;Acc:HGNC:5383]",{"v":4.121667,"d":"4.12"},{"v":2.106742,"d":"2.11"},{"v":2.243304,"d":"2.24"},0,0,0,"inf","inf",{"v":2.76270533843037e-9,"d":"0.00"},{"v":3.13653390453673e-6,"d":"0.00"},"up","yes"]
[62348,0,"chr15","+",32641702,32696889,"ENST00000497208",5,949,"ENSG00000166922","SCG5","GO:0004857(enzyme inhibitor activity);GO:0005515(protein binding);GO:0005525(GTP binding);GO:0005576(extracellular region);GO:0006886(intracellular protein transport);GO:0007218(neuropeptide signaling pathway);GO:0016486(peptide hormone processing);GO:0030141(secretory granule);GO:0043086(negative regulation of catalytic activity);GO:0046883(regulation of hormone secretion);GO:0051082(unfolded protein binding)","NA","NA","NA","secretogranin V [Source:HGNC Symbol;Acc:HGNC:10816]",{"v":2.433562,"d":"2.43"},{"v":5.181351,"d":"5.18"},{"v":4.493018,"d":"4.49"},0,0,0,"inf","inf",{"v":2.86015004665924e-9,"d":"0.00"},{"v":3.14876518773122e-6,"d":"0.00"},"up","yes"]
[3288,0,"chr1","+",27322248,27336400,"ENST00000608611",6,1511,"ENSG00000186501","TMEM222","GO:0016020(membrane);GO:0016021(integral component of membrane)","NA","NA","NA","transmembrane protein 222 [Source:HGNC Symbol;Acc:HGNC:25363]",{"v":0.001647,"d":"0.00"},{"v":0.012471,"d":"0.01"},{"v":0.009964,"d":"0.01"},{"v":5.598204,"d":"5.60"},{"v":6.640409,"d":"6.64"},{"v":2.939235,"d":"2.94"},{"v":0.00158665444534693,"d":"0.00"},{"v":-9.29979632426932,"d":"-9.30"},{"v":2.97108735957283e-9,"d":"0.00"},{"v":3.17469422862591e-6,"d":"0.00"},"down","yes"]
[80431,0,"chr17","-",5514122,5584479,"ENST00000571451",16,5444,"ENSG00000091592","NLRP1","GO:0000166(nucleotide binding);GO:0002376(immune system process);GO:0005515(protein binding);GO:0005524(ATP binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0006915(apoptotic process);GO:0006919(activation of cysteine-type endopeptidase activity involved in apoptotic process);GO:0006954(inflammatory response);GO:0008656(cysteine-type endopeptidase activator activity involved in apoptotic process);GO:0016032(viral process);GO:0019899(enzyme binding);GO:0019904(protein domain specific binding);GO:0032495(response to muramyl dipeptide);GO:0042742(defense response to bacterium);GO:0042981(regulation of apoptotic process);GO:0043280(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process);GO:0045087(innate immune response);GO:0050718(positive regulation of interleukin-1 beta secretion);GO:0050727(regulation of inflammatory response);GO:0051402(neuron apoptotic process);GO:0061702(inflammasome complex);GO:0072558(NLRP1 inflammasome complex);GO:1904784(NLRP1 inflammasome complex assembly)","04621(NOD-like receptor signaling pathway)","K12798","NA","NLR family pyrin domain containing 1 [Source:HGNC Symbol;Acc:HGNC:14374]",0,0,0,{"v":1.454919,"d":"1.45"},{"v":1.201154,"d":"1.20"},{"v":0.284496,"d":"0.28"},"-inf","-inf",{"v":4.06435429898552e-9,"d":"0.00"},{"v":4.21879976234697e-6,"d":"0.00"},"down","yes"]
[168501,0,"chr6","+",29942552,29945884,"ENST00000495183",7,1766,"ENSG00000206503","HLA-A","GO:0000139(Golgi membrane);GO:0002376(immune system process);GO:0002474(antigen processing and presentation of peptide antigen via MHC class I);GO:0002479(antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent);GO:0002480(antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005794(Golgi apparatus);GO:0005886(plasma membrane);GO:0005887(integral component of plasma membrane);GO:0006955(immune response);GO:0009986(cell surface);GO:0012507(ER to Golgi transport vesicle membrane);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016567(protein ubiquitination);GO:0019882(antigen processing and presentation);GO:0030670(phagocytic vesicle membrane);GO:0030881(beta-2-microglobulin binding);GO:0031901(early endosome membrane);GO:0042270(protection from natural killer cell mediated cytotoxicity);GO:0042605(peptide antigen binding);GO:0042612(MHC class I protein complex);GO:0046977(TAP binding);GO:0050776(regulation of immune response);GO:0055038(recycling endosome membrane);GO:0060333(interferon-gamma-mediated signaling pathway);GO:0060337(type I interferon signaling pathway);GO:0070062(extracellular exosome);GO:0071556(integral component of lumenal side of endoplasmic reticulum membrane)","04144(Endocytosis);04145(Phagosome);04218(Cellular senescence);04514(Cell adhesion molecules (CAMs));04612(Antigen processing and presentation);04650(Natural killer cell mediated cytotoxicity);04940(Type I diabetes mellitus);05163(Human cytomegalovirus infection);05165(Human papillomavirus infection);05166(Human T-cell leukemia virus 1 infection);05167(Kaposi sarcoma-associated herpesvirus infection);05168(Herpes simplex virus 1 infection);05169(Epstein-Barr virus infection);05170(Human immunodeficiency virus 1 infection);05203(Viral carcinogenesis);05320(Autoimmune thyroid disease);05330(Allograft rejection);05332(Graft-versus-host disease);05416(Viral myocarditis)","K06751","NA","major histocompatibility complex, class I, A [Source:HGNC Symbol;Acc:HGNC:4931]",0,0,0,{"v":2.630695,"d":"2.63"},{"v":0.971991,"d":"0.97"},{"v":5.861696,"d":"5.86"},"-inf","-inf",{"v":4.65553964399364e-9,"d":"0.00"},{"v":4.69821542406358e-6,"d":"0.00"},"down","yes"]
[75390,0,"chr16","+",57372490,57385044,"ENST00000006053",3,3285,"ENSG00000006210","CX3CL1","GO:0001774(microglial cell activation);GO:0001954(positive regulation of cell-matrix adhesion);GO:0002052(positive regulation of neuroblast proliferation);GO:0002523(leukocyte migration involved in inflammatory response);GO:0002548(monocyte chemotaxis);GO:0002931(response to ischemia);GO:0005102(signaling receptor binding);GO:0005125(cytokine activity);GO:0005178(integrin binding);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0005615(extracellular space);GO:0005886(plasma membrane);GO:0006935(chemotaxis);GO:0006952(defense response);GO:0006954(inflammatory response);GO:0006955(immune response);GO:0007155(cell adhesion);GO:0007186(G protein-coupled receptor signaling pathway);GO:0007267(cell-cell signaling);GO:0007568(aging);GO:0008009(chemokine activity);GO:0008284(positive regulation of cell population proliferation);GO:0009986(cell surface);GO:0010469(regulation of signaling receptor activity);GO:0010812(negative regulation of cell-substrate adhesion);GO:0010976(positive regulation of neuron projection development);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016322(neuron remodeling);GO:0019221(cytokine-mediated signaling pathway);GO:0030336(negative regulation of cell migration);GO:0030593(neutrophil chemotaxis);GO:0030595(leukocyte chemotaxis);GO:0031664(regulation of lipopolysaccharide-mediated signaling pathway);GO:0031737(CX3C chemokine receptor binding);GO:0032233(positive regulation of actin filament bundle assembly);GO:0032690(negative regulation of interleukin-1 alpha production);GO:0032691(negative regulation of interleukin-1 beta production);GO:0032715(negative regulation of interleukin-6 production);GO:0032720(negative regulation of tumor necrosis factor production);GO:0032914(positive regulation of transforming growth factor beta1 production);GO:0033622(integrin activation);GO:0035425(autocrine signaling);GO:0042056(chemoattractant activity);GO:0042060(wound healing);GO:0042995(cell projection);GO:0043005(neuron projection);GO:0043025(neuronal cell body);GO:0043066(negative regulation of apoptotic process);GO:0043123(positive regulation of I-kappaB kinase/NF-kappaB signaling);GO:0043410(positive regulation of MAPK cascade);GO:0043547(positive regulation of GTPase activity);GO:0044297(cell body);GO:0045237(CXCR1 chemokine receptor binding);GO:0045766(positive regulation of angiogenesis);GO:0045944(positive regulation of transcription by RNA polymerase II);GO:0048020(CCR chemokine receptor binding);GO:0048167(regulation of synaptic plasticity);GO:0048245(eosinophil chemotaxis);GO:0048246(macrophage chemotaxis);GO:0048247(lymphocyte chemotaxis);GO:0048471(perinuclear region of cytoplasm);GO:0048661(positive regulation of smooth muscle cell proliferation);GO:0050729(positive regulation of inflammatory response);GO:0050767(regulation of neurogenesis);GO:0050902(leukocyte adhesive activation);GO:0050918(positive chemotaxis);GO:0051041(positive regulation of calcium-independent cell-cell adhesion);GO:0051092(positive regulation of NF-kappaB transcription factor activity);GO:0051281(positive regulation of release of sequestered calcium ion into cytosol);GO:0051897(positive regulation of protein kinase B signaling);GO:0060055(angiogenesis involved in wound healing);GO:0060326(cell chemotaxis);GO:0061518(microglial cell proliferation);GO:0070050(neuron cellular homeostasis);GO:0070098(chemokine-mediated signaling pathway);GO:0070374(positive regulation of ERK1 and ERK2 cascade);GO:0071346(cellular response to interferon-gamma);GO:0071347(cellular response to interleukin-1);GO:0071356(cellular response to tumor necrosis factor);GO:0098609(cell-cell adhesion);GO:0098883(synapse pruning);GO:0110091(negative regulation of hippocampal neuron apoptotic process);GO:1900450(negative regulation of glutamate receptor signaling pathway);GO:1903721(positive regulation of I-kappaB phosphorylation);GO:1903979(negative regulation of microglial cell activation);GO:1904468(negative regulation of tumor necrosis factor secretion);GO:2001223(negative regulation of neuron migration);GO:2001234(negative regulation of apoptotic signaling pathway);GO:2001240(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)","04060(Cytokine-cytokine receptor interaction);04062(Chemokine signaling pathway);04668(TNF signaling pathway);05163(Human cytomegalovirus infection)","K05508","NA","C-X3-C motif chemokine ligand 1 [Source:HGNC Symbol;Acc:HGNC:10647]",0,0,0,{"v":0.961408,"d":"0.96"},{"v":0.834082,"d":"0.83"},{"v":0.819728,"d":"0.82"},"-inf","-inf",{"v":4.85945635949791e-9,"d":"0.00"},{"v":4.77146079839349e-6,"d":"0.00"},"down","yes"]
[14117,0,"chr1","+",173824708,173858517,"ENST00000647645",16,3209,"ENSG00000117593","DARS2","GO:0000049(tRNA binding);GO:0000166(nucleotide binding);GO:0003676(nucleic acid binding);GO:0004812(aminoacyl-tRNA ligase activity);GO:0004815(aspartate-tRNA ligase activity);GO:0005515(protein binding);GO:0005524(ATP binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005739(mitochondrion);GO:0005759(mitochondrial matrix);GO:0006412(translation);GO:0006418(tRNA aminoacylation for protein translation);GO:0016874(ligase activity);GO:0042803(protein homodimerization activity);GO:0043039(tRNA aminoacylation);GO:0050560(aspartate-tRNA(Asn) ligase activity);GO:0070145(mitochondrial asparaginyl-tRNA aminoacylation)","00970(Aminoacyl-tRNA biosynthesis)","K01876","EC:6.1.1.12","aspartyl-tRNA synthetase 2, mitochondrial [Source:HGNC Symbol;Acc:HGNC:25538]",0,0,0,{"v":1.110332,"d":"1.11"},{"v":2.631342,"d":"2.63"},{"v":0.593998,"d":"0.59"},"-inf","-inf",{"v":6.01578106352813e-9,"d":"0.00"},{"v":5.75140331678886e-6,"d":"0.00"},"down","yes"]
[46653,0,"chr12","+",95217799,95301170,"ENST00000548838",10,2338,"ENSG00000028203","VEZT","GO:0001669(acrosomal vesicle);GO:0002142(stereocilia ankle link complex);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0005912(adherens junction);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0017022(myosin binding);GO:0030054(cell junction);GO:0031410(cytoplasmic vesicle);GO:0042995(cell projection);GO:0060171(stereocilium membrane);GO:0098609(cell-cell adhesion)","NA","NA","NA","vezatin, adherens junctions transmembrane protein [Source:HGNC Symbol;Acc:HGNC:18258]",{"v":1.385803,"d":"1.39"},{"v":0.937934,"d":"0.94"},{"v":1.108854,"d":"1.11"},0,0,0,"inf","inf",{"v":7.34264417610922e-9,"d":"0.00"},{"v":6.83995545943713e-6,"d":"0.00"},"up","yes"]
[34328,0,"chr11","+",75399520,75405884,"ENST00000422465",6,903,"ENSG00000149273","RPS3","GO:0000184(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay);GO:0000977(RNA polymerase II regulatory region sequence-specific DNA binding);GO:0003677(DNA binding);GO:0003684(damaged DNA binding);GO:0003723(RNA binding);GO:0003729(mRNA binding);GO:0003735(structural constituent of ribosome);GO:0003906(DNA-(apurinic or apyrimidinic site) endonuclease activity);GO:0004520(endodeoxyribonuclease activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005730(nucleolus);GO:0005737(cytoplasm);GO:0005739(mitochondrion);GO:0005743(mitochondrial inner membrane);GO:0005759(mitochondrial matrix);GO:0005783(endoplasmic reticulum);GO:0005819(spindle);GO:0005829(cytosol);GO:0005840(ribosome);GO:0005844(polysome);GO:0005856(cytoskeleton);GO:0005886(plasma membrane);GO:0005925(focal adhesion);GO:0006281(DNA repair);GO:0006412(translation);GO:0006413(translational initiation);GO:0006417(regulation of translation);GO:0006614(SRP-dependent cotranslational protein targeting to membrane);GO:0006915(apoptotic process);GO:0006974(cellular response to DNA damage stimulus);GO:0006979(response to oxidative stress);GO:0007049(cell cycle);GO:0007059(chromosome segregation);GO:0008017(microtubule binding);GO:0008134(transcription factor binding);GO:0008534(oxidized purine nucleobase lesion DNA N-glycosylase activity);GO:0010628(positive regulation of gene expression);GO:0014069(postsynaptic density);GO:0015631(tubulin binding);GO:0015935(small ribosomal subunit);GO:0016020(membrane);GO:0016829(lyase activity);GO:0017148(negative regulation of translation);GO:0019083(viral transcription);GO:0019899(enzyme binding);GO:0019900(kinase binding);GO:0019901(protein kinase binding);GO:0022627(cytosolic small ribosomal subunit);GO:0030544(Hsp70 protein binding);GO:0031116(positive regulation of microtubule polymerization);GO:0031334(positive regulation of protein complex assembly);GO:0031397(negative regulation of protein ubiquitination);GO:0032079(positive regulation of endodeoxyribonuclease activity);GO:0032357(oxidized purine DNA binding);GO:0032358(oxidized pyrimidine DNA binding);GO:0032587(ruffle membrane);GO:0032743(positive regulation of interleukin-2 production);GO:0042104(positive regulation of activated T cell proliferation);GO:0042769(DNA damage response, detection of DNA damage);GO:0042981(regulation of apoptotic process);GO:0043507(positive regulation of JUN kinase activity);GO:0044390(ubiquitin-like protein conjugating enzyme binding);GO:0044877(protein-containing complex binding);GO:0045202(synapse);GO:0045738(negative regulation of DNA repair);GO:0045739(positive regulation of DNA repair);GO:0050862(positive regulation of T cell receptor signaling pathway);GO:0051018(protein kinase A binding);GO:0051092(positive regulation of NF-kappaB transcription factor activity);GO:0051225(spindle assembly);GO:0051301(cell division);GO:0051536(iron-sulfur cluster binding);GO:0051879(Hsp90 protein binding);GO:0061481(response to TNF agonist);GO:0070062(extracellular exosome);GO:0070181(small ribosomal subunit rRNA binding);GO:0070301(cellular response to hydrogen peroxide);GO:0071159(NF-kappaB complex);GO:0071356(cellular response to tumor necrosis factor);GO:0072686(mitotic spindle);GO:0097100(supercoiled DNA binding);GO:0140078(class I DNA-(apurinic or apyrimidinic site) endonuclease activity);GO:1901224(positive regulation of NIK/NF-kappaB signaling);GO:1902231(positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage);GO:1902546(positive regulation of DNA N-glycosylase activity);GO:1905053(positive regulation of base-excision repair);GO:1990904(ribonucleoprotein complex);GO:2001235(positive regulation of apoptotic signaling pathway);GO:2001272(positive regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis)","03010(Ribosome)","K02985","NA","ribosomal protein S3 [Source:HGNC Symbol;Acc:HGNC:10420]",{"v":14.269836,"d":"14.27"},{"v":1.808721,"d":"1.81"},{"v":4.213629,"d":"4.21"},0,0,0,"inf","inf",{"v":7.81776219503013e-9,"d":"0.00"},{"v":7.10048251363612e-6,"d":"0.00"},"up","yes"]
[128741,0,"chr20","+",63708090,63736141,"ENST00000328969",7,1945,"ENSG00000197114","ZGPAT","GO:0000122(negative regulation of transcription by RNA polymerase II);GO:0000978(RNA polymerase II proximal promoter sequence-specific DNA binding);GO:0000981(DNA-binding transcription factor activity, RNA polymerase II-specific);GO:0001227(DNA-binding transcription repressor activity, RNA polymerase II-specific);GO:0003676(nucleic acid binding);GO:0003677(DNA binding);GO:0003700(DNA-binding transcription factor activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005886(plasma membrane);GO:0007175(negative regulation of epidermal growth factor-activated receptor activity);GO:0043565(sequence-specific DNA binding);GO:0045892(negative regulation of transcription, DNA-templated);GO:0046872(metal ion binding)","NA","NA","NA","zinc finger CCCH-type and G-patch domain containing [Source:HGNC Symbol;Acc:HGNC:15948]",{"v":2.292853,"d":"2.29"},{"v":0.654205,"d":"0.65"},{"v":2.912326,"d":"2.91"},0,0,0,"inf","inf",{"v":9.86950027857061e-9,"d":"0.00"},{"v":8.74534012488952e-6,"d":"0.00"},"up","yes"]
[178191,0,"chr7","-",36855551,37449223,"ENST00000448602",22,2621,"ENSG00000155849","ELMO1","GO:0005085(guanyl-nucleotide exchange factor activity);GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0006909(phagocytosis);GO:0006911(phagocytosis, engulfment);GO:0006915(apoptotic process);GO:0016020(membrane);GO:0016477(cell migration);GO:0016601(Rac protein signal transduction);GO:0017124(SH3 domain binding);GO:0030029(actin filament-based process);GO:0030036(actin cytoskeleton organization);GO:0032045(guanyl-nucleotide exchange factor complex);GO:0038096(Fc-gamma receptor signaling pathway involved in phagocytosis);GO:0048010(vascular endothelial growth factor receptor signaling pathway);GO:0048870(cell motility);GO:0050690(regulation of defense response to virus by virus)","04062(Chemokine signaling pathway);05100(Bacterial invasion of epithelial cells);05131(Shigellosis)","K12366","NA","engulfment and cell motility 1 [Source:HGNC Symbol;Acc:HGNC:16286]",0,0,0,{"v":2.198574,"d":"2.20"},{"v":0.449319,"d":"0.45"},{"v":1.656026,"d":"1.66"},"-inf","-inf",{"v":1.11137661308969e-8,"d":"0.00"},{"v":9.61340770322584e-6,"d":"0.00"},"down","yes"]
[33051,0,"chr11","-",67398201,67401577,"ENST00000532446",7,1465,"ENSG00000172531","PPP1CA","GO:0000164(protein phosphatase type 1 complex);GO:0000784(nuclear chromosome, telomeric region);GO:0004721(phosphoprotein phosphatase activity);GO:0004722(protein serine/threonine phosphatase activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005730(nucleolus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0005913(cell-cell adherens junction);GO:0005975(carbohydrate metabolic process);GO:0005977(glycogen metabolic process);GO:0005979(regulation of glycogen biosynthetic process);GO:0005981(regulation of glycogen catabolic process);GO:0006470(protein dephosphorylation);GO:0007049(cell cycle);GO:0008157(protein phosphatase 1 binding);GO:0010288(response to lead ion);GO:0016311(dephosphorylation);GO:0016787(hydrolase activity);GO:0016791(phosphatase activity);GO:0030324(lung development);GO:0032091(negative regulation of protein binding);GO:0032922(circadian regulation of gene expression);GO:0035970(peptidyl-threonine dephosphorylation);GO:0036496(regulation of translational initiation by eIF2 alpha dephosphorylation);GO:0042587(glycogen granule);GO:0042752(regulation of circadian rhythm);GO:0043005(neuron projection);GO:0043021(ribonucleoprotein complex binding);GO:0043025(neuronal cell body);GO:0043153(entrainment of circadian clock by photoperiod);GO:0043197(dendritic spine);GO:0043204(perikaryon);GO:0044877(protein-containing complex binding);GO:0046872(metal ion binding);GO:0048754(branching morphogenesis of an epithelial tube);GO:0051301(cell division);GO:0060828(regulation of canonical Wnt signaling pathway);GO:0070062(extracellular exosome);GO:0070262(peptidyl-serine dephosphorylation);GO:0072357(PTW/PP1 phosphatase complex);GO:0098609(cell-cell adhesion);GO:0098641(cadherin binding involved in cell-cell adhesion);GO:0098793(presynapse);GO:0098794(postsynapse);GO:0098978(glutamatergic synapse);GO:1904886(beta-catenin destruction complex disassembly);GO:2001241(positive regulation of extrinsic apoptotic signaling pathway in absence of ligand)","03015(mRNA surveillance pathway);04022(cGMP-PKG signaling pathway);04024(cAMP signaling pathway);04114(Oocyte meiosis);04218(Cellular senescence);04261(Adrenergic signaling in cardiomyocytes);04270(Vascular smooth muscle contraction);04390(Hippo signaling pathway);04510(Focal adhesion);04611(Platelet activation);04720(Long-term potentiation);04728(Dopaminergic synapse);04750(Inflammatory mediator regulation of TRP channels);04810(Regulation of actin cytoskeleton);04910(Insulin signaling pathway);04921(Oxytocin signaling pathway);04931(Insulin resistance);05031(Amphetamine addiction);05034(Alcoholism);05168(Herpes simplex virus 1 infection);05205(Proteoglycans in cancer)","NA","NA","protein phosphatase 1 catalytic subunit alpha [Source:HGNC Symbol;Acc:HGNC:9281]",0,0,0,{"v":1.060903,"d":"1.06"},{"v":5.30728,"d":"5.31"},{"v":1.78936,"d":"1.79"},"-inf","-inf",{"v":1.29739953791518e-8,"d":"0.00"},{"v":1.09615174912694e-5,"d":"0.00"},"down","yes"]
[132351,0,"chr22","-",21919427,21938584,"ENST00000407142",6,5587,"ENSG00000100034","PPM1F","GO:0003824(catalytic activity);GO:0004721(phosphoprotein phosphatase activity);GO:0004722(protein serine/threonine phosphatase activity);GO:0004724(magnesium-dependent protein serine/threonine phosphatase activity);GO:0005515(protein binding);GO:0005829(cytosol);GO:0006469(negative regulation of protein kinase activity);GO:0006470(protein dephosphorylation);GO:0006915(apoptotic process);GO:0008138(protein tyrosine/serine/threonine phosphatase activity);GO:0010628(positive regulation of gene expression);GO:0010634(positive regulation of epithelial cell migration);GO:0010811(positive regulation of cell-substrate adhesion);GO:0016576(histone dephosphorylation);GO:0016787(hydrolase activity);GO:0030335(positive regulation of cell migration);GO:0032991(protein-containing complex);GO:0033137(negative regulation of peptidyl-serine phosphorylation);GO:0033192(calmodulin-dependent protein phosphatase activity);GO:0035690(cellular response to drug);GO:0035970(peptidyl-threonine dephosphorylation);GO:0043169(cation binding);GO:0043280(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process);GO:0044387(negative regulation of protein kinase activity by regulation of protein phosphorylation);GO:0045892(negative regulation of transcription, DNA-templated);GO:0045927(positive regulation of growth);GO:0046872(metal ion binding);GO:0048471(perinuclear region of cytoplasm);GO:0050921(positive regulation of chemotaxis);GO:0051224(negative regulation of protein transport);GO:0051496(positive regulation of stress fiber assembly);GO:0051894(positive regulation of focal adhesion assembly);GO:0070262(peptidyl-serine dephosphorylation);GO:0097193(intrinsic apoptotic signaling pathway);GO:1903827(regulation of cellular protein localization);GO:2000048(negative regulation of cell-cell adhesion mediated by cadherin)","NA","K17502","EC:3.1.3.16","protein phosphatase, Mg2+/Mn2+ dependent 1F [Source:HGNC Symbol;Acc:HGNC:19388]",{"v":1.963805,"d":"1.96"},{"v":4.094983,"d":"4.09"},{"v":1.313154,"d":"1.31"},{"v":0.017009,"d":"0.02"},{"v":0.01926,"d":"0.02"},{"v":0.01531,"d":"0.02"},{"v":142.925260280347,"d":"142.93"},{"v":7.15911710733219,"d":"7.16"},{"v":1.37031478524737e-8,"d":"0.00"},{"v":1.13144400336447e-5,"d":"0.00"},"up","yes"]
[114433,0,"chr2","-",85342088,85350891,"ENST00000429806",8,2335,"ENSG00000042445","RETSAT","GO:0005640(nuclear outer membrane);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0016020(membrane);GO:0016491(oxidoreductase activity);GO:0031965(nuclear membrane);GO:0042572(retinol metabolic process);GO:0051786(all-trans-retinol 13,14-reductase activity);GO:0055114(oxidation-reduction process)","00830(Retinol metabolism)","K09516","EC:1.3.99.23","retinol saturase [Source:HGNC Symbol;Acc:HGNC:25991]",{"v":4.70815,"d":"4.71"},{"v":0.38311,"d":"0.38"},{"v":2.34261,"d":"2.34"},0,0,0,"inf","inf",{"v":1.67061293315969e-8,"d":"0.00"},{"v":1.34874150803759e-5,"d":"0.00"},"up","yes"]
[207349,0,"chrX","+",154397154,154400917,"ENST00000369817",8,1284,"ENSG00000147403","RPL10","GO:0000027(ribosomal large subunit assembly);GO:0000122(negative regulation of transcription by RNA polymerase II);GO:0000184(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay);GO:0003723(RNA binding);GO:0003735(structural constituent of ribosome);GO:0005515(protein binding);GO:0005622(intracellular);GO:0005634(nucleus);GO:0005783(endoplasmic reticulum);GO:0005790(smooth endoplasmic reticulum);GO:0005829(cytosol);GO:0005840(ribosome);GO:0006412(translation);GO:0006413(translational initiation);GO:0006417(regulation of translation);GO:0006614(SRP-dependent cotranslational protein targeting to membrane);GO:0007275(multicellular organism development);GO:0016020(membrane);GO:0019083(viral transcription);GO:0022625(cytosolic large ribosomal subunit);GO:0032991(protein-containing complex);GO:0043066(negative regulation of apoptotic process);GO:0045182(translation regulator activity);GO:1990403(embryonic brain development)","03010(Ribosome)","K02866","NA","ribosomal protein L10 [Source:HGNC Symbol;Acc:HGNC:10298]",{"v":294.459503,"d":"294.46"},0,{"v":254.40358,"d":"254.40"},0,0,0,"inf","inf",{"v":1.74533064340463e-8,"d":"0.00"},{"v":1.37843178858457e-5,"d":"0.00"},"up","yes"]
[89462,0,"chr17","-",68267026,68291127,"ENST00000580666",6,3691,"ENSG00000108932","SLC16A6","GO:0005886(plasma membrane);GO:0005887(integral component of plasma membrane);GO:0008028(monocarboxylic acid transmembrane transporter activity);GO:0015293(symporter activity);GO:0015718(monocarboxylic acid transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0055085(transmembrane transport)","NA","K08183","NA","solute carrier family 16 member 6 [Source:HGNC Symbol;Acc:HGNC:10927]",{"v":0.53565,"d":"0.54"},{"v":1.021904,"d":"1.02"},{"v":0.458617,"d":"0.46"},0,0,0,"inf","inf",{"v":1.79309601599392e-8,"d":"0.00"},{"v":1.38602506938423e-5,"d":"0.00"},"up","yes"]
[37219,0,"chr11","+",119168729,119184014,"ENST00000292199",10,3744,"ENSG00000160703","NLRX1","GO:0000166(nucleotide binding);GO:0002376(immune system process);GO:0005515(protein binding);GO:0005524(ATP binding);GO:0005737(cytoplasm);GO:0005739(mitochondrion);GO:0005741(mitochondrial outer membrane);GO:0005886(plasma membrane);GO:0016020(membrane);GO:0016032(viral process);GO:0030054(cell junction);GO:0032480(negative regulation of type I interferon production);GO:0032688(negative regulation of interferon-beta production);GO:0032715(negative regulation of interleukin-6 production);GO:0035556(intracellular signal transduction);GO:0039536(negative regulation of RIG-I signaling pathway);GO:0043124(negative regulation of I-kappaB kinase/NF-kappaB signaling);GO:0045087(innate immune response);GO:0045824(negative regulation of innate immune response);GO:0050728(negative regulation of inflammatory response)","04621(NOD-like receptor signaling pathway);04622(RIG-I-like receptor signaling pathway);05164(Influenza A)","K12653","NA","NLR family member X1 [Source:HGNC Symbol;Acc:HGNC:29890]",0,0,0,{"v":0.28657,"d":"0.29"},{"v":1.668309,"d":"1.67"},{"v":0.897718,"d":"0.90"},"-inf","-inf",{"v":1.9544645233426e-8,"d":"0.00"},{"v":1.46568949640382e-5,"d":"0.00"},"down","yes"]
[46410,0,"chr12","-",91145259,91178552,"ENST00000425043",4,1438,"ENSG00000011465","DCN","GO:0001822(kidney development);GO:0001890(placenta development);GO:0003723(RNA binding);GO:0005515(protein binding);GO:0005518(collagen binding);GO:0005539(glycosaminoglycan binding);GO:0005576(extracellular region);GO:0005589(collagen type VI trimer);GO:0005615(extracellular space);GO:0005796(Golgi lumen);GO:0007519(skeletal muscle tissue development);GO:0007568(aging);GO:0009612(response to mechanical stimulus);GO:0009887(animal organ morphogenesis);GO:0010508(positive regulation of autophagy);GO:0010596(negative regulation of endothelial cell migration);GO:0014068(positive regulation of phosphatidylinositol 3-kinase signaling);GO:0016239(positive regulation of macroautophagy);GO:0016525(negative regulation of angiogenesis);GO:0019800(peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan);GO:0030021(extracellular matrix structural constituent conferring compression resistance);GO:0030198(extracellular matrix organization);GO:0030206(chondroitin sulfate biosynthetic process);GO:0030207(chondroitin sulfate catabolic process);GO:0030208(dermatan sulfate biosynthetic process);GO:0031012(extracellular matrix);GO:0032496(response to lipopolysaccharide);GO:0042060(wound healing);GO:0043202(lysosomal lumen);GO:0045944(positive regulation of transcription by RNA polymerase II);GO:0047485(protein N-terminus binding);GO:0050840(extracellular matrix binding);GO:0051901(positive regulation of mitochondrial depolarization);GO:0062023(collagen-containing extracellular matrix);GO:0090141(positive regulation of mitochondrial fission);GO:1900747(negative regulation of vascular endothelial growth factor signaling pathway)","04350(TGF-beta signaling pathway);05205(Proteoglycans in cancer)","NA","NA","decorin [Source:HGNC Symbol;Acc:HGNC:2705]",{"v":21.693018,"d":"21.69"},{"v":1.116123,"d":"1.12"},{"v":1.05995,"d":"1.06"},0,0,0,"inf","inf",{"v":1.9897829501389e-8,"d":"0.00"},{"v":1.46568949640382e-5,"d":"0.00"},"up","yes"]
[94418,0,"chr18","-",46084150,46098295,"ENST00000590156",12,1931,"ENSG00000152234","ATP5F1A","GO:0000166(nucleotide binding);GO:0000275(mitochondrial proton-transporting ATP synthase complex, catalytic core F(1));GO:0001937(negative regulation of endothelial cell proliferation);GO:0003723(RNA binding);GO:0005515(protein binding);GO:0005524(ATP binding);GO:0005739(mitochondrion);GO:0005743(mitochondrial inner membrane);GO:0005753(mitochondrial proton-transporting ATP synthase complex);GO:0005759(mitochondrial matrix);GO:0005886(plasma membrane);GO:0006629(lipid metabolic process);GO:0006754(ATP biosynthetic process);GO:0006811(ion transport);GO:0006979(response to oxidative stress);GO:0008180(COP9 signalosome);GO:0015986(ATP synthesis coupled proton transport);GO:0016020(membrane);GO:0016887(ATPase activity);GO:0022857(transmembrane transporter activity);GO:0022900(electron transport chain);GO:0032559(adenyl ribonucleotide binding);GO:0042288(MHC class I protein binding);GO:0042407(cristae formation);GO:0042776(mitochondrial ATP synthesis coupled proton transport);GO:0043531(ADP binding);GO:0043532(angiostatin binding);GO:0043536(positive regulation of blood vessel endothelial cell migration);GO:0045259(proton-transporting ATP synthase complex);GO:0045261(proton-transporting ATP synthase complex, catalytic core F(1));GO:0046034(ATP metabolic process);GO:0046933(proton-transporting ATP synthase activity, rotational mechanism);GO:0070062(extracellular exosome);GO:0099132(ATP hydrolysis coupled cation transmembrane transport);GO:1902600(proton transmembrane transport)","00190(Oxidative phosphorylation);04714(Thermogenesis);05010(Alzheimer disease);05012(Parkinson disease);05016(Huntington disease)","NA","NA","ATP synthase F1 subunit alpha [Source:HGNC Symbol;Acc:HGNC:823]",0,{"v":130.703003,"d":"130.70"},{"v":176.381912,"d":"176.38"},0,0,0,"inf","inf",{"v":2.01718895734079e-8,"d":"0.00"},{"v":1.46568949640382e-5,"d":"0.00"},"up","yes"]
[182429,0,"chr7","-",102483144,102517781,"ENST00000465829",21,2931,"ENSG00000170667","RASA4B","GO:0005096(GTPase activator activity);GO:0005543(phospholipid binding);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0007165(signal transduction);GO:0016020(membrane);GO:0035556(intracellular signal transduction);GO:0043087(regulation of GTPase activity);GO:0043547(positive regulation of GTPase activity);GO:0046580(negative regulation of Ras protein signal transduction);GO:0046872(metal ion binding);GO:0071277(cellular response to calcium ion)","04014(Ras signaling pathway)","K17630","NA","RAS p21 protein activator 4B [Source:HGNC Symbol;Acc:HGNC:35202]",{"v":0.033496,"d":"0.03"},0,0,{"v":4.467309,"d":"4.47"},{"v":5.102124,"d":"5.10"},{"v":6.035604,"d":"6.04"},{"v":0.00214648641973742,"d":"0.00"},{"v":-8.86380723940463,"d":"-8.86"},{"v":2.56879322748836e-8,"d":"0.00"},{"v":1.82988741087553e-5,"d":"0.00"},"down","yes"]
[137291,0,"chr3","-",15450483,15498872,"ENST00000383781",17,2784,"ENSG00000206561","COLQ","GO:0001507(acetylcholine catabolic process in synaptic cleft);GO:0005201(extracellular matrix structural constituent);GO:0005515(protein binding);GO:0005581(collagen trimer);GO:0005604(basement membrane);GO:0005615(extracellular space);GO:0005886(plasma membrane);GO:0008201(heparin binding);GO:0008582(regulation of synaptic growth at neuromuscular junction);GO:0030054(cell junction);GO:0030198(extracellular matrix organization);GO:0031012(extracellular matrix);GO:0031594(neuromuscular junction);GO:0042135(neurotransmitter catabolic process);GO:0043083(synaptic cleft);GO:0045202(synapse);GO:0062023(collagen-containing extracellular matrix);GO:0071340(skeletal muscle acetylcholine-gated channel clustering);GO:0090150(establishment of protein localization to membrane)","NA","NA","NA","collagen like tail subunit of asymmetric acetylcholinesterase [Source:HGNC Symbol;Acc:HGNC:2226]",{"v":1.296778,"d":"1.30"},{"v":1.872015,"d":"1.87"},{"v":1.925256,"d":"1.93"},{"v":0.007552,"d":"0.01"},0,0,{"v":674.529793432203,"d":"674.53"},{"v":9.39773835702183,"d":"9.40"},{"v":2.81785108378172e-8,"d":"0.00"},{"v":1.9333127745315e-5,"d":"0.00"},"up","yes"]
[69874,0,"chr16","-",1962061,1964631,"ENST00000530225",5,765,"ENSG00000140988","RPS2","GO:0000184(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay);GO:0003723(RNA binding);GO:0003729(mRNA binding);GO:0003735(structural constituent of ribosome);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0005840(ribosome);GO:0005925(focal adhesion);GO:0006364(rRNA processing);GO:0006412(translation);GO:0006413(translational initiation);GO:0006614(SRP-dependent cotranslational protein targeting to membrane);GO:0015935(small ribosomal subunit);GO:0016020(membrane);GO:0017134(fibroblast growth factor binding);GO:0019083(viral transcription);GO:0019899(enzyme binding);GO:0022627(cytosolic small ribosomal subunit);GO:0045202(synapse);GO:0045296(cadherin binding);GO:0051443(positive regulation of ubiquitin-protein transferase activity);GO:0070062(extracellular exosome);GO:0071353(cellular response to interleukin-4);GO:1990904(ribonucleoprotein complex)","03010(Ribosome)","K02981","NA","ribosomal protein S2 [Source:HGNC Symbol;Acc:HGNC:10404]",0,0,0,0,{"v":251.527908,"d":"251.53"},{"v":273.694855,"d":"273.69"},"-inf","-inf",{"v":2.82041225021111e-8,"d":"0.00"},{"v":1.9333127745315e-5,"d":"0.00"},"down","yes"]
[193427,0,"chr8","+",143558346,143563062,"ENST00000262580",11,1723,"ENSG00000104518","GSDMD","GO:0001786(phosphatidylserine binding);GO:0002376(immune system process);GO:0005515(protein binding);GO:0005546(phosphatidylinositol-4,5-bisphosphate binding);GO:0005576(extracellular region);GO:0005615(extracellular space);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0006954(inflammatory response);GO:0012501(programmed cell death);GO:0016020(membrane);GO:0019835(cytolysis);GO:0031668(cellular response to extracellular stimulus);GO:0035580(specific granule lumen);GO:0035915(pore formation in membrane of other organism);GO:0043312(neutrophil degranulation);GO:0045087(innate immune response);GO:0046931(pore complex assembly);GO:0050718(positive regulation of interleukin-1 beta secretion);GO:0050829(defense response to Gram-negative bacterium);GO:0050830(defense response to Gram-positive bacterium);GO:0051260(protein homooligomerization);GO:0061702(inflammasome complex);GO:0070269(pyroptosis);GO:0070273(phosphatidylinositol-4-phosphate binding);GO:0070300(phosphatidic acid binding);GO:0072559(NLRP3 inflammasome complex);GO:1901612(cardiolipin binding);GO:1904724(tertiary granule lumen);GO:1904813(ficolin-1-rich granule lumen)","04621(NOD-like receptor signaling pathway)","K20917","NA","gasdermin D [Source:HGNC Symbol;Acc:HGNC:25697]",{"v":4.632477,"d":"4.63"},{"v":2.878552,"d":"2.88"},{"v":4.776681,"d":"4.78"},{"v":0.030658,"d":"0.03"},{"v":0.023531,"d":"0.02"},{"v":0.011837,"d":"0.01"},{"v":186.104110501923,"d":"186.10"},{"v":7.53996611048748,"d":"7.54"},{"v":3.09775881410374e-8,"d":"0.00"},{"v":2.08410329104424e-5,"d":"0.00"},"up","yes"]
[20321,0,"chr10","-",35008552,35090642,"ENST00000626172",20,4115,"ENSG00000108094","CUL2","GO:0000082(G1/S transition of mitotic cell cycle);GO:0005515(protein binding);GO:0005654(nucleoplasm);GO:0005730(nucleolus);GO:0005829(cytosol);GO:0006511(ubiquitin-dependent protein catabolic process);GO:0007050(cell cycle arrest);GO:0008285(negative regulation of cell population proliferation);GO:0016032(viral process);GO:0016567(protein ubiquitination);GO:0019005(SCF ubiquitin ligase complex);GO:0030163(protein catabolic process);GO:0030891(VCB complex);GO:0031146(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process);GO:0031461(cullin-RING ubiquitin ligase complex);GO:0031462(Cul2-RING ubiquitin ligase complex);GO:0031625(ubiquitin protein ligase binding);GO:0043161(proteasome-mediated ubiquitin-dependent protein catabolic process);GO:0043687(post-translational protein modification);GO:0044877(protein-containing complex binding);GO:0061418(regulation of transcription from RNA polymerase II promoter in response to hypoxia);GO:0061630(ubiquitin protein ligase activity);GO:0097193(intrinsic apoptotic signaling pathway)","04066(HIF-1 signaling pathway);04120(Ubiquitin mediated proteolysis);05200(Pathways in cancer);05211(Renal cell carcinoma)","NA","NA","cullin 2 [Source:HGNC Symbol;Acc:HGNC:2552]",{"v":0.695614,"d":"0.70"},{"v":1.231517,"d":"1.23"},{"v":0.218363,"d":"0.22"},0,0,0,"inf","inf",{"v":3.26281503302863e-8,"d":"0.00"},{"v":2.15523763908964e-5,"d":"0.00"},"up","yes"]
[60837,0,"chr14","+",103629297,103686186,"ENST00000445352",15,2416,"ENSG00000126214","KLC1","GO:0003774(motor activity);GO:0003777(microtubule motor activity);GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005856(cytoskeleton);GO:0005871(kinesin complex);GO:0005874(microtubule);GO:0006890(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum);GO:0007018(microtubule-based movement);GO:0016020(membrane);GO:0016032(viral process);GO:0019886(antigen processing and presentation of exogenous peptide antigen via MHC class II);GO:0030426(growth cone);GO:0031410(cytoplasmic vesicle);GO:0035617(stress granule disassembly);GO:0042995(cell projection)","05132(Salmonella infection)","K10407","NA","kinesin light chain 1 [Source:HGNC Symbol;Acc:HGNC:6387]",{"v":0.143626,"d":"0.14"},0,0,{"v":24.236267,"d":"24.24"},{"v":22.693153,"d":"22.69"},{"v":20.748386,"d":"20.75"},{"v":0.0021222023657209,"d":"0.00"},{"v":-8.88022205154712,"d":"-8.88"},{"v":3.63913882076129e-8,"d":"0.00"},{"v":2.36089130996889e-5,"d":"0.00"},"down","yes"]
[185334,0,"chr7","-",150791301,150800364,"ENST00000326442",7,1115,"ENSG00000106565","TMEM176B","GO:0005634(nucleus);GO:0009887(animal organ morphogenesis);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0030154(cell differentiation);GO:0031965(nuclear membrane);GO:2001199(negative regulation of dendritic cell differentiation)","NA","NA","NA","transmembrane protein 176B [Source:HGNC Symbol;Acc:HGNC:29596]",0,0,0,{"v":2.021876,"d":"2.02"},{"v":1.866404,"d":"1.87"},{"v":1.783111,"d":"1.78"},"-inf","-inf",{"v":3.79457302474866e-8,"d":"0.00"},{"v":2.41854101735296e-5,"d":"0.00"},"down","yes"]
[102642,0,"chr19","+",35648323,35658782,"ENST00000649813",4,488,"ENSG00000126267","COX6B1","GO:0004129(cytochrome-c oxidase activity);GO:0005515(protein binding);GO:0005739(mitochondrion);GO:0005743(mitochondrial inner membrane);GO:0005758(mitochondrial intermembrane space);GO:0006123(mitochondrial electron transport, cytochrome c to oxygen);GO:0021762(substantia nigra development);GO:0045277(respiratory chain complex IV);GO:1902600(proton transmembrane transport)","00190(Oxidative phosphorylation);04260(Cardiac muscle contraction);04714(Thermogenesis);04932(Non-alcoholic fatty liver disease (NAFLD));05010(Alzheimer disease);05012(Parkinson disease);05016(Huntington disease)","NA","NA","cytochrome c oxidase subunit 6B1 [Source:HGNC Symbol;Acc:HGNC:2280]",{"v":134.718353,"d":"134.72"},{"v":0.27327,"d":"0.27"},{"v":120.194801,"d":"120.19"},{"v":0.129663,"d":"0.13"},{"v":0.105696,"d":"0.11"},{"v":0.046776,"d":"0.05"},{"v":904.48339979088,"d":"904.48"},{"v":9.82095021472279,"d":"9.82"},{"v":4.21617862308419e-8,"d":"0.00"},{"v":2.64092705821808e-5,"d":"0.00"},"up","yes"]
[182426,0,"chr7","-",102482445,102493311,"ENST00000477184",5,1787,"ENSG00000170667","RASA4B","GO:0005096(GTPase activator activity);GO:0005543(phospholipid binding);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0007165(signal transduction);GO:0016020(membrane);GO:0035556(intracellular signal transduction);GO:0043087(regulation of GTPase activity);GO:0043547(positive regulation of GTPase activity);GO:0046580(negative regulation of Ras protein signal transduction);GO:0046872(metal ion binding);GO:0071277(cellular response to calcium ion)","04014(Ras signaling pathway)","K17630","NA","RAS p21 protein activator 4B [Source:HGNC Symbol;Acc:HGNC:35202]",{"v":2.395678,"d":"2.40"},{"v":1.191232,"d":"1.19"},{"v":1.123263,"d":"1.12"},0,{"v":8.6e-5,"d":"0.00"},0,{"v":54769.4534883721,"d":"54769.45"},{"v":15.7410838641965,"d":"15.74"},{"v":5.52368775506252e-8,"d":"0.00"},{"v":3.40128095154952e-5,"d":"0.00"},"up","yes"]
[143780,0,"chr3","-",126006358,126056838,"ENST00000383598",10,2330,"ENSG00000114544","SLC41A3","GO:0005515(protein binding);GO:0005886(plasma membrane);GO:0006812(cation transport);GO:0008324(cation transmembrane transporter activity);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0098655(cation transmembrane transport)","NA","K15122","NA","solute carrier family 41 member 3 [Source:HGNC Symbol;Acc:HGNC:31046]",0,0,0,{"v":1.951199,"d":"1.95"},{"v":1.315641,"d":"1.32"},{"v":0.285342,"d":"0.29"},"-inf","-inf",{"v":5.8171886442731e-8,"d":"0.00"},{"v":3.52230772410736e-5,"d":"0.00"},"down","yes"]
[144082,0,"chr3","+",129249632,129277771,"ENST00000515725",23,3231,"ENSG00000181789","COPG1","GO:0000139(Golgi membrane);GO:0005198(structural molecule activity);GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005793(endoplasmic reticulum-Golgi intermediate compartment);GO:0005794(Golgi apparatus);GO:0005829(cytosol);GO:0006886(intracellular protein transport);GO:0006888(endoplasmic reticulum to Golgi vesicle-mediated transport);GO:0006890(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum);GO:0006891(intra-Golgi vesicle-mediated transport);GO:0009306(protein secretion);GO:0015031(protein transport);GO:0016020(membrane);GO:0016192(vesicle-mediated transport);GO:0030117(membrane coat);GO:0030126(COPI vesicle coat);GO:0030133(transport vesicle);GO:0030663(COPI-coated vesicle membrane);GO:0031410(cytoplasmic vesicle);GO:0051683(establishment of Golgi localization);GO:0072384(organelle transport along microtubule)","NA","K17267","NA","coatomer protein complex subunit gamma 1 [Source:HGNC Symbol;Acc:HGNC:2236]",{"v":31.97897,"d":"31.98"},{"v":30.330814,"d":"30.33"},0,0,0,0,"inf","inf",{"v":6.70105163297663e-8,"d":"0.00"},{"v":3.99097058731215e-5,"d":"0.00"},"up","yes"]
[127361,0,"chr20","+",45812644,45816952,"ENST00000356455",6,777,"ENSG00000175063","UBE2C","GO:0000151(ubiquitin ligase complex);GO:0000166(nucleotide binding);GO:0004842(ubiquitin-protein transferase activity);GO:0005515(protein binding);GO:0005524(ATP binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005680(anaphase-promoting complex);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0006511(ubiquitin-dependent protein catabolic process);GO:0007049(cell cycle);GO:0010458(exit from mitosis);GO:0010994(free ubiquitin chain polymerization);GO:0016567(protein ubiquitination);GO:0016740(transferase activity);GO:0031145(anaphase-promoting complex-dependent catabolic process);GO:0031536(positive regulation of exit from mitosis);GO:0044389(ubiquitin-like protein ligase binding);GO:0051301(cell division);GO:0061631(ubiquitin conjugating enzyme activity);GO:0070936(protein K48-linked ubiquitination);GO:0070979(protein K11-linked ubiquitination);GO:1901990(regulation of mitotic cell cycle phase transition);GO:1904668(positive regulation of ubiquitin protein ligase activity)","04120(Ubiquitin mediated proteolysis)","K06688","EC:2.3.2.23","ubiquitin conjugating enzyme E2 C [Source:HGNC Symbol;Acc:HGNC:15937]",0,{"v":0.027399,"d":"0.03"},0,{"v":5.013261,"d":"5.01"},{"v":4.161391,"d":"4.16"},{"v":4.2455,"d":"4.25"},{"v":0.00204163112310501,"d":"0.00"},{"v":-8.93606205749652,"d":"-8.94"},{"v":6.90221551973849e-8,"d":"0.00"},{"v":4.04447564245321e-5,"d":"0.00"},"down","yes"]
[23662,0,"chr10","-",100505628,100529871,"ENST00000529568",12,1952,"ENSG00000255339","AL133352","GO:0003954(NADH dehydrogenase activity);GO:0005739(mitochondrion);GO:0005747(mitochondrial respiratory chain complex I);GO:0006120(mitochondrial electron transport, NADH to ubiquinone);GO:0008137(NADH dehydrogenase (ubiquinone) activity);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0055114(oxidation-reduction process)","NA","NA","NA","NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 8, 19kDa (NDUFB8) and SEC31 homolog B (S. cerevisiae) (SEC31B) readthrough",{"v":0.42291,"d":"0.42"},{"v":5.19275,"d":"5.19"},{"v":1.174386,"d":"1.17"},0,0,0,"inf","inf",{"v":7.01841775017037e-8,"d":"0.00"},{"v":4.04728756926491e-5,"d":"0.00"},"up","yes"]
[127909,0,"chr20","+",54208300,54219285,"ENST00000493356",4,659,"ENSG00000101132","PFDN4","GO:0005515(protein binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005739(mitochondrion);GO:0005829(cytosol);GO:0006457(protein folding);GO:0016272(prefoldin complex);GO:0051082(unfolded protein binding);GO:0051087(chaperone binding)","NA","K09550","NA","prefoldin subunit 4 [Source:HGNC Symbol;Acc:HGNC:8868]",{"v":4.530486,"d":"4.53"},{"v":1.301201,"d":"1.30"},{"v":4.189038,"d":"4.19"},0,0,0,"inf","inf",{"v":7.54357214633982e-8,"d":"0.00"},{"v":4.28215587619571e-5,"d":"0.00"},"up","yes"]
[89000,0,"chr17","-",63832604,63842466,"ENST00000225742",13,1800,"ENSG00000108604","SMARCD2","GO:0000790(nuclear chromatin);GO:0000978(RNA polymerase II proximal promoter sequence-specific DNA binding);GO:0000980(RNA polymerase II distal enhancer sequence-specific DNA binding);GO:0003713(transcription coactivator activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0006325(chromatin organization);GO:0006337(nucleosome disassembly);GO:0006338(chromatin remodeling);GO:0006357(regulation of transcription by RNA polymerase II);GO:0016514(SWI/SNF complex);GO:0031492(nucleosomal DNA binding);GO:0032991(protein-containing complex);GO:0043044(ATP-dependent chromatin remodeling);GO:1903508(positive regulation of nucleic acid-templated transcription)","04714(Thermogenesis);05225(Hepatocellular carcinoma)","NA","NA","SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2 [Source:HGNC Symbol;Acc:HGNC:11107]",{"v":0.457222,"d":"0.46"},{"v":0.004409,"d":"0.00"},{"v":0.477786,"d":"0.48"},{"v":31.028208,"d":"31.03"},{"v":34.694633,"d":"34.69"},{"v":24.111151,"d":"24.11"},{"v":0.0104572554228693,"d":"0.01"},{"v":-6.57935193354174,"d":"-6.58"},{"v":9.15825438402324e-8,"d":"0.00"},{"v":5.11875971956253e-5,"d":"0.00"},"down","yes"]
[31957,0,"chr11","-",64765652,64777760,"ENST00000433274",13,2317,"ENSG00000168066","SF1","GO:0000245(spliceosomal complex assembly);GO:0000389(mRNA 3'-splice site recognition);GO:0000398(mRNA splicing, via spliceosome);GO:0003676(nucleic acid binding);GO:0003714(transcription corepressor activity);GO:0003723(RNA binding);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005681(spliceosomal complex);GO:0005840(ribosome);GO:0006397(mRNA processing);GO:0008270(zinc ion binding);GO:0008380(RNA splicing);GO:0016604(nuclear body);GO:0030238(male sex determination);GO:0030575(nuclear body organization);GO:0033327(Leydig cell differentiation);GO:0042802(identical protein binding);GO:0045131(pre-mRNA branch point binding);GO:0046872(metal ion binding);GO:0048662(negative regulation of smooth muscle cell proliferation);GO:0050810(regulation of steroid biosynthetic process);GO:1903507(negative regulation of nucleic acid-templated transcription)","NA","K13095","NA","splicing factor 1 [Source:HGNC Symbol;Acc:HGNC:12950]",{"v":0.009061,"d":"0.01"},0,0,{"v":1.351723,"d":"1.35"},{"v":1.131133,"d":"1.13"},{"v":1.21628,"d":"1.22"},{"v":0.0024494909081472,"d":"0.00"},{"v":-8.67330234792815,"d":"-8.67"},{"v":1.19379899718695e-7,"d":"0.00"},{"v":6.57132084360637e-5,"d":"0.00"},"down","yes"]
[65583,0,"chr15","-",66500131,66501381,"ENST00000563473",4,475,"ENSG00000174444","RPL4","GO:0000184(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay);GO:0003723(RNA binding);GO:0003735(structural constituent of ribosome);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005730(nucleolus);GO:0005737(cytoplasm);GO:0005791(rough endoplasmic reticulum);GO:0005829(cytosol);GO:0005840(ribosome);GO:0005925(focal adhesion);GO:0006412(translation);GO:0006413(translational initiation);GO:0006614(SRP-dependent cotranslational protein targeting to membrane);GO:0016020(membrane);GO:0019083(viral transcription);GO:0022625(cytosolic large ribosomal subunit);GO:0070062(extracellular exosome);GO:1990904(ribonucleoprotein complex)","03010(Ribosome)","K02930","NA","ribosomal protein L4 [Source:HGNC Symbol;Acc:HGNC:10353]",0,0,0,{"v":7.224613,"d":"7.22"},{"v":2.868607,"d":"2.87"},{"v":2.814688,"d":"2.81"},"-inf","-inf",{"v":1.22514379280714e-7,"d":"0.00"},{"v":6.64320507353486e-5,"d":"0.00"},"down","yes"]
[42606,0,"chr12","-",49636499,49707405,"ENST00000335154",26,12625,"ENSG00000161791","FMNL3","GO:0001525(angiogenesis);GO:0003779(actin binding);GO:0005737(cytoplasm);GO:0005794(Golgi apparatus);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0007010(cytoskeleton organization);GO:0007275(multicellular organism development);GO:0008360(regulation of cell shape);GO:0016020(membrane);GO:0016043(cellular component organization);GO:0016477(cell migration);GO:0017048(Rho GTPase binding);GO:0030036(actin cytoskeleton organization);GO:0032794(GTPase activating protein binding);GO:0043231(intracellular membrane-bounded organelle)","NA","NA","NA","formin like 3 [Source:HGNC Symbol;Acc:HGNC:23698]",0,0,0,0,{"v":4.626499,"d":"4.63"},{"v":4.863407,"d":"4.86"},"-inf","-inf",{"v":1.72046966329571e-7,"d":"0.00"},{"v":9.19186218640196e-5,"d":"0.00"},"down","yes"]
[152208,0,"chr4","+",75514473,75530026,"ENST00000380837",4,3423,"ENSG00000174796","THAP6","GO:0000981(DNA-binding transcription factor activity, RNA polymerase II-specific);GO:0003676(nucleic acid binding);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0006357(regulation of transcription by RNA polymerase II);GO:0015630(microtubule cytoskeleton);GO:0046872(metal ion binding)","NA","K23207","NA","THAP domain containing 6 [Source:HGNC Symbol;Acc:HGNC:23189]",0,0,0,{"v":0.130866,"d":"0.13"},{"v":1.325825,"d":"1.33"},{"v":0.682882,"d":"0.68"},"-inf","-inf",{"v":1.75730610206112e-7,"d":"0.00"},{"v":9.25259865041745e-5,"d":"0.00"},"down","yes"]
[120621,0,"chr2","-",199269500,199465108,"ENST00000614512",9,4972,"ENSG00000119042","SATB2","GO:0000118(histone deacetylase complex);GO:0000122(negative regulation of transcription by RNA polymerase II);GO:0000977(RNA polymerase II regulatory region sequence-specific DNA binding);GO:0000978(RNA polymerase II proximal promoter sequence-specific DNA binding);GO:0000981(DNA-binding transcription factor activity, RNA polymerase II-specific);GO:0001228(DNA-binding transcription activator activity, RNA polymerase II-specific);GO:0001764(neuron migration);GO:0002076(osteoblast development);GO:0003677(DNA binding);GO:0003682(chromatin binding);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005667(transcription factor complex);GO:0006325(chromatin organization);GO:0006338(chromatin remodeling);GO:0007275(multicellular organism development);GO:0009880(embryonic pattern specification);GO:0010468(regulation of gene expression);GO:0016363(nuclear matrix);GO:0021902(commitment of neuronal cell to specific neuron type in forebrain);GO:0043565(sequence-specific DNA binding);GO:0045944(positive regulation of transcription by RNA polymerase II);GO:0048704(embryonic skeletal system morphogenesis);GO:0051216(cartilage development);GO:0060021(roof of mouth development);GO:0071310(cellular response to organic substance)","NA","K23226","NA","SATB homeobox 2 [Source:HGNC Symbol;Acc:HGNC:21637]",{"v":0.137182,"d":"0.14"},{"v":0.277583,"d":"0.28"},{"v":2.075823,"d":"2.08"},0,0,0,"inf","inf",{"v":2.01362089925294e-7,"d":"0.00"},{"v":0.000104506924671227,"d":"0.00"},"up","yes"]
[83708,0,"chr17","-",29625938,29930152,"ENST00000269033",15,9327,"ENSG00000141298","SSH2","GO:0003779(actin binding);GO:0004721(phosphoprotein phosphatase activity);GO:0004725(protein tyrosine phosphatase activity);GO:0005615(extracellular space);GO:0005737(cytoplasm);GO:0005856(cytoskeleton);GO:0006470(protein dephosphorylation);GO:0008064(regulation of actin polymerization or depolymerization);GO:0008138(protein tyrosine/serine/threonine phosphatase activity);GO:0010591(regulation of lamellipodium assembly);GO:0016311(dephosphorylation);GO:0016787(hydrolase activity);GO:0016791(phosphatase activity);GO:0030036(actin cytoskeleton organization);GO:0030335(positive regulation of cell migration);GO:0035335(peptidyl-tyrosine dephosphorylation);GO:0050770(regulation of axonogenesis)","04360(Axon guidance);04810(Regulation of actin cytoskeleton)","K05766","3.1.3.48;EC:3.1.3.16","slingshot protein phosphatase 2 [Source:HGNC Symbol;Acc:HGNC:30580]",{"v":8.467973,"d":"8.47"},{"v":4.253211,"d":"4.25"},0,0,0,0,"inf","inf",{"v":2.04832725222069e-7,"d":"0.00"},{"v":0.00010481088601856,"d":"0.00"},"up","yes"]
[98877,0,"chr19","+",10687605,10692398,"ENST00000586544",3,3859,"ENSG00000129351","ILF3","GO:0003677(DNA binding);GO:0003723(RNA binding);GO:0003725(double-stranded RNA binding);GO:0003727(single-stranded RNA binding);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005730(nucleolus);GO:0005737(cytoplasm);GO:0005739(mitochondrion);GO:0006468(protein phosphorylation);GO:0016020(membrane);GO:0017091(AU-rich element binding);GO:0017148(negative regulation of translation);GO:0045071(negative regulation of viral genome replication);GO:0045892(negative regulation of transcription, DNA-templated);GO:0045893(positive regulation of transcription, DNA-templated);GO:0051607(defense response to virus);GO:1990904(ribonucleoprotein complex)","NA","K13090","NA","interleukin enhancer binding factor 3 [Source:HGNC Symbol;Acc:HGNC:6038]",{"v":0.058376,"d":"0.06"},{"v":0.029278,"d":"0.03"},{"v":0.043046,"d":"0.04"},{"v":0.466135,"d":"0.47"},{"v":6.620714,"d":"6.62"},{"v":8.295544,"d":"8.30"},{"v":0.00849672739475581,"d":"0.01"},{"v":-6.87887700582153,"d":"-6.88"},{"v":2.10219666119827e-7,"d":"0.00"},{"v":0.000106073339862963,"d":"0.00"},"down","yes"]
[142768,0,"chr3","+",111948971,111975932,"ENST00000638331",10,2626,"ENSG00000144824","PHLDB2","GO:0000226(microtubule cytoskeleton organization);GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0005925(focal adhesion);GO:0010470(regulation of gastrulation);GO:0010717(regulation of epithelial to mesenchymal transition);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0031252(cell leading edge);GO:0045111(intermediate filament cytoskeleton);GO:0045180(basal cortex);GO:0045184(establishment of protein localization);GO:0045296(cadherin binding);GO:0051497(negative regulation of stress fiber assembly);GO:0051895(negative regulation of focal adhesion assembly);GO:0070507(regulation of microtubule cytoskeleton organization);GO:1903690(negative regulation of wound healing, spreading of epidermal cells);GO:1904261(positive regulation of basement membrane assembly involved in embryonic body morphogenesis)","NA","NA","NA","pleckstrin homology like domain family B member 2 [Source:HGNC Symbol;Acc:HGNC:29573]",{"v":0.002633,"d":"0.00"},{"v":10.437199,"d":"10.44"},{"v":12.301308,"d":"12.30"},0,0,0,"inf","inf",{"v":2.24624444728458e-7,"d":"0.00"},{"v":0.000111789124342259,"d":"0.00"},"up","yes"]
[73387,0,"chr16","-",29483642,29485859,"ENST00000458643",2,1342,"ENSG00000169203","NPIPB12","GO:0005654(nucleoplasm);GO:0016020(membrane);GO:0016021(integral component of membrane)","NA","NA","NA","nuclear pore complex interacting protein family, member B12 [Source:HGNC Symbol;Acc:HGNC:37491]",0,0,0,{"v":1.513804,"d":"1.51"},{"v":1.540969,"d":"1.54"},{"v":1.255414,"d":"1.26"},"-inf","-inf",{"v":2.94903677672996e-7,"d":"0.00"},{"v":0.000144781764998107,"d":"0.00"},"down","yes"]
[168913,0,"chr6","-",31268749,31272086,"ENST00000383329",8,1554,"ENSG00000204525","HLA-C","GO:0000139(Golgi membrane);GO:0002376(immune system process);GO:0002474(antigen processing and presentation of peptide antigen via MHC class I);GO:0002479(antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent);GO:0002480(antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent);GO:0005515(protein binding);GO:0005783(endoplasmic reticulum);GO:0005794(Golgi apparatus);GO:0005886(plasma membrane);GO:0006955(immune response);GO:0009986(cell surface);GO:0012507(ER to Golgi transport vesicle membrane);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0019882(antigen processing and presentation);GO:0030667(secretory granule membrane);GO:0030670(phagocytic vesicle membrane);GO:0031901(early endosome membrane);GO:0042605(peptide antigen binding);GO:0042612(MHC class I protein complex);GO:0043312(neutrophil degranulation);GO:0050776(regulation of immune response);GO:0055038(recycling endosome membrane);GO:0060333(interferon-gamma-mediated signaling pathway);GO:0060337(type I interferon signaling pathway);GO:0070062(extracellular exosome);GO:0071556(integral component of lumenal side of endoplasmic reticulum membrane)","04144(Endocytosis);04145(Phagosome);04218(Cellular senescence);04514(Cell adhesion molecules (CAMs));04612(Antigen processing and presentation);04650(Natural killer cell mediated cytotoxicity);04940(Type I diabetes mellitus);05163(Human cytomegalovirus infection);05165(Human papillomavirus infection);05166(Human T-cell leukemia virus 1 infection);05167(Kaposi sarcoma-associated herpesvirus infection);05168(Herpes simplex virus 1 infection);05169(Epstein-Barr virus infection);05170(Human immunodeficiency virus 1 infection);05203(Viral carcinogenesis);05320(Autoimmune thyroid disease);05330(Allograft rejection);05332(Graft-versus-host disease);05416(Viral myocarditis)","K06751","NA","major histocompatibility complex, class I, C [Source:HGNC Symbol;Acc:HGNC:4933]",0,0,0,{"v":34.707546,"d":"34.71"},0,{"v":22.311272,"d":"22.31"},"-inf","-inf",{"v":3.09046840692065e-7,"d":"0.00"},{"v":0.000149702289631236,"d":"0.00"},"down","yes"]
[49177,0,"chr12","-",122272834,122380494,"ENST00000540338",25,4400,"ENSG00000130779","CLIP1","GO:0000278(mitotic cell cycle);GO:0000776(kinetochore);GO:0001578(microtubule bundle formation);GO:0001726(ruffle);GO:0005515(protein binding);GO:0005635(nuclear envelope);GO:0005737(cytoplasm);GO:0005768(endosome);GO:0005813(centrosome);GO:0005829(cytosol);GO:0005856(cytoskeleton);GO:0005874(microtubule);GO:0005881(cytoplasmic microtubule);GO:0005882(intermediate filament);GO:0008017(microtubule binding);GO:0008270(zinc ion binding);GO:0015630(microtubule cytoskeleton);GO:0015631(tubulin binding);GO:0016020(membrane);GO:0030659(cytoplasmic vesicle membrane);GO:0031116(positive regulation of microtubule polymerization);GO:0031410(cytoplasmic vesicle);GO:0035371(microtubule plus-end);GO:0042803(protein homodimerization activity);GO:0042995(cell projection);GO:0044354(macropinosome);GO:0044861(protein transport into plasma membrane raft);GO:0046872(metal ion binding);GO:0051010(microtubule plus-end binding)","04150(mTOR signaling pathway)","K10421","NA","CAP-Gly domain containing linker protein 1 [Source:HGNC Symbol;Acc:HGNC:10461]",{"v":10.394553,"d":"10.39"},{"v":10.585164,"d":"10.59"},0,0,0,0,"inf","inf",{"v":3.27982048498729e-7,"d":"0.00"},{"v":0.000156784050288932,"d":"0.00"},"up","yes"]
[179870,0,"chr7","-",73536371,73557671,"ENST00000411832",5,1458,"ENSG00000106635","BCL7B","GO:0003779(actin binding);GO:0005515(protein binding);GO:0005575(cellular_component);GO:0006915(apoptotic process);GO:0008150(biological_process);GO:0016055(Wnt signaling pathway);GO:0030154(cell differentiation)","NA","NA","NA","BCL7B, BAF complex component [Source:HGNC Symbol;Acc:HGNC:1005]",0,{"v":0.003465,"d":"0.00"},0,{"v":0.419903,"d":"0.42"},{"v":1.981681,"d":"1.98"},{"v":6.758734,"d":"6.76"},{"v":0.000378261977368035,"d":"0.00"},{"v":-11.3683266145803,"d":"-11.37"},{"v":3.45172785468847e-7,"d":"0.00"},{"v":0.000162858796053029,"d":"0.00"},"down","yes"]
[144623,0,"chr3","-",136336236,136752378,"ENST00000236698",33,5951,"ENSG00000118007","STAG1","GO:0000775(chromosome, centromeric region);GO:0000785(chromatin);GO:0001228(DNA-binding transcription activator activity, RNA polymerase II-specific);GO:0003682(chromatin binding);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005694(chromosome);GO:0005829(cytosol);GO:0007049(cell cycle);GO:0007059(chromosome segregation);GO:0007062(sister chromatid cohesion);GO:0008278(cohesin complex);GO:0016363(nuclear matrix);GO:0016604(nuclear body);GO:0045944(positive regulation of transcription by RNA polymerase II);GO:0051301(cell division);GO:0097431(mitotic spindle pole);GO:1901673(regulation of mitotic spindle assembly)","04110(Cell cycle)","K06671","NA","stromal antigen 1 [Source:HGNC Symbol;Acc:HGNC:11354]",0,0,0,0,{"v":7.398705,"d":"7.40"},{"v":7.000446,"d":"7.00"},"-inf","-inf",{"v":3.83099242509298e-7,"d":"0.00"},{"v":0.000178435839491831,"d":"0.00"},"down","yes"]
[205398,0,"chrX","+",108582492,108627269,"ENST00000483338",20,3622,"ENSG00000188153","COL4A5","GO:0005201(extracellular matrix structural constituent);GO:0005576(extracellular region);GO:0005581(collagen trimer);GO:0005587(collagen type IV trimer);GO:0005604(basement membrane);GO:0005615(extracellular space);GO:0005788(endoplasmic reticulum lumen);GO:0007528(neuromuscular junction development);GO:0030020(extracellular matrix structural constituent conferring tensile strength);GO:0030198(extracellular matrix organization);GO:0031012(extracellular matrix);GO:0031594(neuromuscular junction);GO:0038063(collagen-activated tyrosine kinase receptor signaling pathway);GO:0062023(collagen-containing extracellular matrix)","04151(PI3K-Akt signaling pathway);04510(Focal adhesion);04512(ECM-receptor interaction);04926(Relaxin signaling pathway);04933(AGE-RAGE signaling pathway in diabetic complications);04974(Protein digestion and absorption);05146(Amoebiasis);05165(Human papillomavirus infection);05200(Pathways in cancer);05222(Small cell lung cancer)","K06237","NA","collagen type IV alpha 5 chain [Source:HGNC Symbol;Acc:HGNC:2207]",0,0,0,{"v":0.179139,"d":"0.18"},{"v":0.74085,"d":"0.74"},{"v":0.726508,"d":"0.73"},"-inf","-inf",{"v":4.09743380807967e-7,"d":"0.00"},{"v":0.00018843008892093,"d":"0.00"},"down","yes"]
[49276,0,"chr12","-",122928994,122966509,"ENST00000346530",11,3399,"ENSG00000150967","ABCB9","GO:0000166(nucleotide binding);GO:0005515(protein binding);GO:0005524(ATP binding);GO:0005764(lysosome);GO:0005765(lysosomal membrane);GO:0015031(protein transport);GO:0015440(peptide-transporting ATPase activity);GO:0015833(peptide transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016887(ATPase activity);GO:0022857(transmembrane transporter activity);GO:0030176(integral component of endoplasmic reticulum membrane);GO:0042626(ATPase activity, coupled to transmembrane movement of substances);GO:0042803(protein homodimerization activity);GO:0043231(intracellular membrane-bounded organelle);GO:0055085(transmembrane transport);GO:1904680(peptide transmembrane transporter activity)","02010(ABC transporters);04142(Lysosome)","K05656","NA","ATP binding cassette subfamily B member 9 [Source:HGNC Symbol;Acc:HGNC:50]",0,0,0,{"v":0.602691,"d":"0.60"},{"v":0.305155,"d":"0.31"},{"v":0.792136,"d":"0.79"},"-inf","-inf",{"v":4.22150935058577e-7,"d":"0.00"},{"v":0.000191709293383476,"d":"0.00"},"down","yes"]
[119441,0,"chr2","-",174799512,174847596,"ENST00000650731",8,1719,"ENSG00000128656","CHN1","GO:0005070(SH3/SH2 adaptor activity);GO:0005096(GTPase activator activity);GO:0005515(protein binding);GO:0005829(cytosol);GO:0007165(signal transduction);GO:0007399(nervous system development);GO:0008045(motor neuron axon guidance);GO:0009967(positive regulation of signal transduction);GO:0035556(intracellular signal transduction);GO:0043087(regulation of GTPase activity);GO:0043547(positive regulation of GTPase activity);GO:0046872(metal ion binding);GO:0046875(ephrin receptor binding);GO:0048013(ephrin receptor signaling pathway);GO:0050770(regulation of axonogenesis);GO:0051056(regulation of small GTPase mediated signal transduction)","NA","NA","NA","chimerin 1 [Source:HGNC Symbol;Acc:HGNC:1943]",{"v":22.807663,"d":"22.81"},{"v":27.21055,"d":"27.21"},{"v":23.796421,"d":"23.80"},{"v":0.921703,"d":"0.92"},{"v":1.975281,"d":"1.98"},{"v":1.059824,"d":"1.06"},{"v":18.6550962290816,"d":"18.66"},{"v":4.22149789695365,"d":"4.22"},{"v":4.7876998972373e-7,"d":"0.00"},{"v":0.000214737206502014,"d":"0.00"},"up","yes"]
[166822,0,"chr6","+",2768773,2785745,"ENST00000380764",6,1557,"ENSG00000124535","WRNIP1","GO:0000166(nucleotide binding);GO:0000731(DNA synthesis involved in DNA repair);GO:0000733(DNA strand renaturation);GO:0000784(nuclear chromosome, telomeric region);GO:0002376(immune system process);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0005524(ATP binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0006260(DNA replication);GO:0006261(DNA-dependent DNA replication);GO:0006281(DNA repair);GO:0006282(regulation of DNA repair);GO:0006310(DNA recombination);GO:0006974(cellular response to DNA damage stimulus);GO:0008047(enzyme activator activity);GO:0016020(membrane);GO:0016787(hydrolase activity);GO:0016887(ATPase activity);GO:0030174(regulation of DNA-dependent DNA replication initiation);GO:0030894(replisome);GO:0033567(DNA replication, Okazaki fragment processing);GO:0042802(identical protein binding);GO:0043085(positive regulation of catalytic activity);GO:0043142(single-stranded DNA-dependent ATPase activity);GO:0045087(innate immune response);GO:0046872(metal ion binding);GO:0048471(perinuclear region of cytoplasm)","NA","K07478","NA","Werner helicase interacting protein 1 [Source:HGNC Symbol;Acc:HGNC:20876]",{"v":0.000134,"d":"0.00"},{"v":0.000803,"d":"0.00"},{"v":0.000223,"d":"0.00"},{"v":21.662689,"d":"21.66"},{"v":20.486746,"d":"20.49"},{"v":0.002003,"d":"0.00"},{"v":2.75198203202463e-5,"d":"0.00"},{"v":-15.1491694238712,"d":"-15.15"},{"v":5.39019204068283e-7,"d":"0.00"},{"v":0.00023881180102196,"d":"0.00"},"down","yes"]
[201486,0,"chrX","+",11759604,11775736,"ENST00000649602",13,2230,"ENSG00000005302","MSL3","GO:0000123(histone acetyltransferase complex);GO:0003677(DNA binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0006325(chromatin organization);GO:0006342(chromatin silencing);GO:0006355(regulation of transcription, DNA-templated);GO:0016573(histone acetylation);GO:0016575(histone deacetylation);GO:0035064(methylated histone binding);GO:0035267(NuA4 histone acetyltransferase complex);GO:0043967(histone H4 acetylation);GO:0043968(histone H2A acetylation);GO:0043984(histone H4-K16 acetylation);GO:0072487(MSL complex)","NA","K18403","NA","MSL complex subunit 3 [Source:HGNC Symbol;Acc:HGNC:7370]",{"v":0.97956,"d":"0.98"},{"v":0.885311,"d":"0.89"},{"v":0.648389,"d":"0.65"},0,0,0,"inf","inf",{"v":5.94004184373663e-7,"d":"0.00"},{"v":0.000260002072509581,"d":"0.00"},"up","yes"]
[159510,0,"chr5","+",66158127,66180811,"ENST00000284041",12,3751,"ENSG00000153914","SREK1","GO:0000381(regulation of alternative mRNA splicing, via spliceosome);GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005681(spliceosomal complex);GO:0006397(mRNA processing);GO:0008380(RNA splicing);GO:0016607(nuclear speck)","NA","K13165","NA","splicing regulatory glutamic acid and lysine rich protein 1 [Source:HGNC Symbol;Acc:HGNC:17882]",0,0,0,{"v":8.831395,"d":"8.83"},0,{"v":9.257948,"d":"9.26"},"-inf","-inf",{"v":6.16923950303753e-7,"d":"0.00"},{"v":0.000266819608506373,"d":"0.00"},"down","yes"]
[201481,0,"chrX","+",11758556,11775726,"ENST00000398527",13,2329,"ENSG00000005302","MSL3","GO:0000123(histone acetyltransferase complex);GO:0003677(DNA binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0006325(chromatin organization);GO:0006342(chromatin silencing);GO:0006355(regulation of transcription, DNA-templated);GO:0016573(histone acetylation);GO:0016575(histone deacetylation);GO:0035064(methylated histone binding);GO:0035267(NuA4 histone acetyltransferase complex);GO:0043967(histone H4 acetylation);GO:0043968(histone H2A acetylation);GO:0043984(histone H4-K16 acetylation);GO:0072487(MSL complex)","NA","K18403","NA","MSL complex subunit 3 [Source:HGNC Symbol;Acc:HGNC:7370]",0,0,0,{"v":0.695973,"d":"0.70"},{"v":0.65099,"d":"0.65"},{"v":0.895466,"d":"0.90"},"-inf","-inf",{"v":7.43247138595495e-7,"d":"0.00"},{"v":0.000317672571119698,"d":"0.00"},"down","yes"]
[157763,0,"chr5","-",16666562,16742228,"ENST00000505695",23,4803,"ENSG00000145555","MYO10","GO:0000166(nucleotide binding);GO:0001726(ruffle);GO:0003774(motor activity);GO:0003779(actin binding);GO:0005515(protein binding);GO:0005516(calmodulin binding);GO:0005524(ATP binding);GO:0005547(phosphatidylinositol-3,4,5-trisphosphate binding);GO:0005730(nucleolus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005856(cytoskeleton);GO:0005886(plasma membrane);GO:0005938(cell cortex);GO:0007165(signal transduction);GO:0008360(regulation of cell shape);GO:0016020(membrane);GO:0016459(myosin complex);GO:0022409(positive regulation of cell-cell adhesion);GO:0030027(lamellipodium);GO:0030175(filopodium);GO:0030507(spectrin binding);GO:0030705(cytoskeleton-dependent intracellular transport);GO:0030898(actin-dependent ATPase activity);GO:0031527(filopodium membrane);GO:0032433(filopodium tip);GO:0038096(Fc-gamma receptor signaling pathway involved in phagocytosis);GO:0042995(cell projection);GO:0043005(neuron projection);GO:0043025(neuronal cell body);GO:0051015(actin filament binding);GO:0051489(regulation of filopodium assembly);GO:0060002(plus-end directed microfilament motor activity)","04666(Fc gamma R-mediated phagocytosis)","K12559","NA","myosin X [Source:HGNC Symbol;Acc:HGNC:7593]",0,0,0,{"v":6.890822,"d":"6.89"},0,{"v":6.011303,"d":"6.01"},"-inf","-inf",{"v":7.53411693563415e-7,"d":"0.00"},{"v":0.000318272637525103,"d":"0.00"},"down","yes"]
[141156,0,"chr3","+",58008400,58172251,"ENST00000429972",46,9430,"ENSG00000136068","FLNB","GO:0001725(stress fiber);GO:0003334(keratinocyte development);GO:0003382(epithelial cell morphogenesis);GO:0003723(RNA binding);GO:0003779(actin binding);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005856(cytoskeleton);GO:0005886(plasma membrane);GO:0005903(brush border);GO:0005925(focal adhesion);GO:0005938(cell cortex);GO:0007016(cytoskeletal anchoring at plasma membrane);GO:0007165(signal transduction);GO:0007275(multicellular organism development);GO:0007517(muscle organ development);GO:0007519(skeletal muscle tissue development);GO:0015629(actin cytoskeleton);GO:0016021(integral component of membrane);GO:0030018(Z disc);GO:0030036(actin cytoskeleton organization);GO:0030154(cell differentiation);GO:0042802(identical protein binding);GO:0043005(neuron projection);GO:0043025(neuronal cell body);GO:0045296(cadherin binding);GO:0045335(phagocytic vesicle);GO:0070062(extracellular exosome);GO:0071346(cellular response to interferon-gamma)","04010(MAPK signaling pathway);04510(Focal adhesion);05132(Salmonella infection);05205(Proteoglycans in cancer)","NA","NA","filamin B [Source:HGNC Symbol;Acc:HGNC:3755]",0,0,0,{"v":4.628246,"d":"4.63"},{"v":2.64835,"d":"2.65"},0,"-inf","-inf",{"v":7.78300965924551e-7,"d":"0.00"},{"v":0.000324771082345084,"d":"0.00"},"down","yes"]
[9236,0,"chr1","+",109984765,110023741,"ENST00000393614",17,4313,"ENSG00000168710","AHCYL1","GO:0003723(RNA binding);GO:0004013(adenosylhomocysteinase activity);GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0006378(mRNA polyadenylation);GO:0006611(protein export from nucleus);GO:0006730(one-carbon metabolic process);GO:0010765(positive regulation of sodium ion transport);GO:0016020(membrane);GO:0016324(apical plasma membrane);GO:0016787(hydrolase activity);GO:0031440(regulation of mRNA 3'-end processing);GO:0032412(regulation of ion transmembrane transporter activity);GO:0033353(S-adenosylmethionine cycle);GO:0038166(angiotensin-activated signaling pathway);GO:0042045(epithelial fluid transport);GO:0042802(identical protein binding);GO:0043231(intracellular membrane-bounded organelle);GO:0044070(regulation of anion transport);GO:0051592(response to calcium ion);GO:0070062(extracellular exosome);GO:1903779(regulation of cardiac conduction)","00270(Cysteine and methionine metabolism)","K01251","EC:3.3.1.1","adenosylhomocysteinase like 1 [Source:HGNC Symbol;Acc:HGNC:344]",{"v":16.853928,"d":"16.85"},0,{"v":7.86688,"d":"7.87"},{"v":0.000588,"d":"0.00"},0,0,{"v":42042.1904761905,"d":"42042.19"},{"v":15.3595502178983,"d":"15.36"},{"v":7.86673692440611e-7,"d":"0.00"},{"v":0.000324771082345084,"d":"0.00"},"up","yes"]
[38054,0,"chr11","-",128460244,128522201,"ENST00000526145",7,3389,"ENSG00000134954","ETS1","GO:0000978(RNA polymerase II proximal promoter sequence-specific DNA binding);GO:0000981(DNA-binding transcription factor activity, RNA polymerase II-specific);GO:0001228(DNA-binding transcription activator activity, RNA polymerase II-specific);GO:0001666(response to hypoxia);GO:0002376(immune system process);GO:0003677(DNA binding);GO:0003700(DNA-binding transcription factor activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005667(transcription factor complex);GO:0005737(cytoplasm);GO:0006355(regulation of transcription, DNA-templated);GO:0006357(regulation of transcription by RNA polymerase II);GO:0006955(immune response);GO:0007565(female pregnancy);GO:0008134(transcription factor binding);GO:0008284(positive regulation of cell population proliferation);GO:0008285(negative regulation of cell population proliferation);GO:0009611(response to wounding);GO:0009612(response to mechanical stimulus);GO:0010595(positive regulation of endothelial cell migration);GO:0010628(positive regulation of gene expression);GO:0010715(regulation of extracellular matrix disassembly);GO:0021854(hypothalamus development);GO:0021983(pituitary gland development);GO:0030154(cell differentiation);GO:0030335(positive regulation of cell migration);GO:0030578(PML body organization);GO:0032355(response to estradiol);GO:0034616(response to laminar fluid shear stress);GO:0035035(histone acetyltransferase binding);GO:0042802(identical protein binding);GO:0043536(positive regulation of blood vessel endothelial cell migration);GO:0043565(sequence-specific DNA binding);GO:0044849(estrous cycle);GO:0045648(positive regulation of erythrocyte differentiation);GO:0045765(regulation of angiogenesis);GO:0045766(positive regulation of angiogenesis);GO:0045893(positive regulation of transcription, DNA-templated);GO:0045944(positive regulation of transcription by RNA polymerase II);GO:0048870(cell motility);GO:0050728(negative regulation of inflammatory response);GO:0050729(positive regulation of inflammatory response);GO:0051272(positive regulation of cellular component movement);GO:0060055(angiogenesis involved in wound healing);GO:0061614(pri-miRNA transcription by RNA polymerase II);GO:0070301(cellular response to hydrogen peroxide);GO:0070555(response to interleukin-1);GO:1904996(positive regulation of leukocyte adhesion to vascular endothelial cell);GO:1990837(sequence-specific double-stranded DNA binding)","04014(Ras signaling pathway);04218(Cellular senescence);05166(Human T-cell leukemia virus 1 infection);05200(Pathways in cancer);05211(Renal cell carcinoma)","K02678","NA","ETS proto-oncogene 1, transcription factor [Source:HGNC Symbol;Acc:HGNC:3488]",0,0,0,0,{"v":10.138997,"d":"10.14"},{"v":9.43205,"d":"9.43"},"-inf","-inf",{"v":7.96994339644186e-7,"d":"0.00"},{"v":0.000325334880441273,"d":"0.00"},"down","yes"]
[107473,0,"chr19","-",52797408,52821633,"ENST00000457749",4,4558,"ENSG00000198538","ZNF28","GO:0000981(DNA-binding transcription factor activity, RNA polymerase II-specific);GO:0003676(nucleic acid binding);GO:0003677(DNA binding);GO:0005622(intracellular);GO:0005634(nucleus);GO:0006355(regulation of transcription, DNA-templated);GO:0006357(regulation of transcription by RNA polymerase II);GO:0046872(metal ion binding)","NA","NA","NA","zinc finger protein 28 [Source:HGNC Symbol;Acc:HGNC:13073]",{"v":0.177636,"d":"0.18"},{"v":0.233113,"d":"0.23"},{"v":1.230793,"d":"1.23"},0,{"v":0.000396,"d":"0.00"},0,{"v":4145.30808080808,"d":"4145.31"},{"v":12.0172636119892,"d":"12.02"},{"v":8.6638772558033e-7,"d":"0.00"},{"v":0.000349731845225927,"d":"0.00"},"up","yes"]
[152319,0,"chr4","-",76158760,76213799,"ENST00000639300",11,4554,"ENSG00000138760","SCARB2","GO:0000139(Golgi membrane);GO:0001618(virus receptor activity);GO:0001786(phosphatidylserine binding);GO:0004888(transmembrane signaling receptor activity);GO:0005044(scavenger receptor activity);GO:0005515(protein binding);GO:0005548(phospholipid transporter activity);GO:0005764(lysosome);GO:0005765(lysosomal membrane);GO:0005789(endoplasmic reticulum membrane);GO:0005886(plasma membrane);GO:0005925(focal adhesion);GO:0006622(protein targeting to lysosome);GO:0006898(receptor-mediated endocytosis);GO:0008565(protein transporter activity);GO:0010008(endosome membrane);GO:0010976(positive regulation of neuron projection development);GO:0015485(cholesterol binding);GO:0015917(aminophospholipid transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016032(viral process);GO:0019899(enzyme binding);GO:0030665(clathrin-coated vesicle membrane);GO:0030666(endocytic vesicle membrane);GO:0031210(phosphatidylcholine binding);GO:0031902(late endosome membrane);GO:0042803(protein homodimerization activity);GO:0043202(lysosomal lumen);GO:0043471(regulation of cellular carbohydrate catabolic process);GO:0046718(viral entry into host cell);GO:0051087(chaperone binding);GO:0061024(membrane organization);GO:0070062(extracellular exosome);GO:1904978(regulation of endosome organization);GO:1905123(regulation of glucosylceramidase activity);GO:1905671(regulation of lysosome organization)","04142(Lysosome)","NA","NA","scavenger receptor class B member 2 [Source:HGNC Symbol;Acc:HGNC:1665]",0,0,0,{"v":10.84756,"d":"10.85"},0,{"v":3.553896,"d":"3.55"},"-inf","-inf",{"v":9.11235220410967e-7,"d":"0.00"},{"v":0.000362841094267852,"d":"0.00"},"down","yes"]
[35733,0,"chr11","-",102942995,102955732,"ENST00000260302",10,2714,"ENSG00000137745","MMP13","GO:0001958(endochondral ossification);GO:0003417(growth plate cartilage development);GO:0004222(metalloendopeptidase activity);GO:0005509(calcium ion binding);GO:0005518(collagen binding);GO:0005576(extracellular region);GO:0005581(collagen trimer);GO:0005615(extracellular space);GO:0006508(proteolysis);GO:0008233(peptidase activity);GO:0008237(metallopeptidase activity);GO:0008270(zinc ion binding);GO:0016787(hydrolase activity);GO:0022617(extracellular matrix disassembly);GO:0030198(extracellular matrix organization);GO:0030282(bone mineralization);GO:0030574(collagen catabolic process);GO:0031012(extracellular matrix);GO:0044267(cellular protein metabolic process);GO:0046872(metal ion binding);GO:0051216(cartilage development);GO:0060349(bone morphogenesis);GO:1904645(response to amyloid-beta)","04657(IL-17 signaling pathway);04926(Relaxin signaling pathway);04928(Parathyroid hormone synthesis, secretion and action)","K07994","EC:3.4.24.-","matrix metallopeptidase 13 [Source:HGNC Symbol;Acc:HGNC:7159]",{"v":12.97471,"d":"12.97"},{"v":16.929306,"d":"16.93"},{"v":13.356982,"d":"13.36"},{"v":0.524749,"d":"0.52"},{"v":0.952265,"d":"0.95"},{"v":0.981712,"d":"0.98"},{"v":17.5948836917981,"d":"17.59"},{"v":4.13708407229857,"d":"4.14"},{"v":9.18837893549198e-7,"d":"0.00"},{"v":0.000362841094267852,"d":"0.00"},"up","yes"]
[205918,0,"chrX","+",123960519,124101498,"ENST00000218089",35,5218,"ENSG00000101972","STAG2","GO:0000775(chromosome, centromeric region);GO:0000785(chromatin);GO:0003682(chromatin binding);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005694(chromosome);GO:0005829(cytosol);GO:0007049(cell cycle);GO:0007059(chromosome segregation);GO:0007062(sister chromatid cohesion);GO:0008278(cohesin complex);GO:0016020(membrane);GO:0016363(nuclear matrix);GO:0032876(negative regulation of DNA endoreduplication);GO:0051301(cell division);GO:0051321(meiotic cell cycle);GO:0097431(mitotic spindle pole);GO:1901673(regulation of mitotic spindle assembly)","04110(Cell cycle)","K06671","NA","stromal antigen 2 [Source:HGNC Symbol;Acc:HGNC:11355]",0,0,0,{"v":5.325238,"d":"5.33"},{"v":6.324393,"d":"6.32"},0,"-inf","-inf",{"v":9.59482876216776e-7,"d":"0.00"},{"v":0.000374817342935005,"d":"0.00"},"down","yes"]
[53687,0,"chr13","+",114234934,114272657,"ENST00000650489",20,2204,"ENSG00000130177","CDC16","GO:0000278(mitotic cell cycle);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005680(anaphase-promoting complex);GO:0005737(cytoplasm);GO:0005813(centrosome);GO:0005815(microtubule organizing center);GO:0005819(spindle);GO:0005829(cytosol);GO:0005856(cytoskeleton);GO:0005876(spindle microtubule);GO:0006511(ubiquitin-dependent protein catabolic process);GO:0007049(cell cycle);GO:0007088(regulation of mitotic nuclear division);GO:0008283(cell population proliferation);GO:0016567(protein ubiquitination);GO:0031145(anaphase-promoting complex-dependent catabolic process);GO:0051301(cell division);GO:0070979(protein K11-linked ubiquitination);GO:1901990(regulation of mitotic cell cycle phase transition)","04110(Cell cycle);04114(Oocyte meiosis);04120(Ubiquitin mediated proteolysis);04914(Progesterone-mediated oocyte maturation);05166(Human T-cell leukemia virus 1 infection)","K03353","NA","cell division cycle 16 [Source:HGNC Symbol;Acc:HGNC:1720]",{"v":0.007794,"d":"0.01"},{"v":9.143489,"d":"9.14"},{"v":3.653741,"d":"3.65"},0,0,0,"inf","inf",{"v":1.02167112544959e-6,"d":"0.00"},{"v":0.000394865021144505,"d":"0.00"},"up","yes"]
[152321,0,"chr4","-",76158761,76213824,"ENST00000640640",12,4608,"ENSG00000138760","SCARB2","GO:0000139(Golgi membrane);GO:0001618(virus receptor activity);GO:0001786(phosphatidylserine binding);GO:0004888(transmembrane signaling receptor activity);GO:0005044(scavenger receptor activity);GO:0005515(protein binding);GO:0005548(phospholipid transporter activity);GO:0005764(lysosome);GO:0005765(lysosomal membrane);GO:0005789(endoplasmic reticulum membrane);GO:0005886(plasma membrane);GO:0005925(focal adhesion);GO:0006622(protein targeting to lysosome);GO:0006898(receptor-mediated endocytosis);GO:0008565(protein transporter activity);GO:0010008(endosome membrane);GO:0010976(positive regulation of neuron projection development);GO:0015485(cholesterol binding);GO:0015917(aminophospholipid transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016032(viral process);GO:0019899(enzyme binding);GO:0030665(clathrin-coated vesicle membrane);GO:0030666(endocytic vesicle membrane);GO:0031210(phosphatidylcholine binding);GO:0031902(late endosome membrane);GO:0042803(protein homodimerization activity);GO:0043202(lysosomal lumen);GO:0043471(regulation of cellular carbohydrate catabolic process);GO:0046718(viral entry into host cell);GO:0051087(chaperone binding);GO:0061024(membrane organization);GO:0070062(extracellular exosome);GO:1904978(regulation of endosome organization);GO:1905123(regulation of glucosylceramidase activity);GO:1905671(regulation of lysosome organization)","04142(Lysosome)","NA","NA","scavenger receptor class B member 2 [Source:HGNC Symbol;Acc:HGNC:1665]",0,{"v":8.301705,"d":"8.30"},{"v":4.729311,"d":"4.73"},0,0,0,"inf","inf",{"v":1.14276128377776e-6,"d":"0.00"},{"v":0.000432585537491081,"d":"0.00"},"up","yes"]
[179128,0,"chr7","-",55470614,55571868,"ENST00000428648",5,2866,"ENSG00000154978","VOPP1","GO:0005768(endosome);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0030659(cytoplasmic vesicle membrane);GO:0031301(integral component of organelle membrane);GO:0031410(cytoplasmic vesicle)","NA","NA","NA","VOPP1, WBP1/VOPP1 family member [Source:HGNC Symbol;Acc:HGNC:34518]",{"v":8.712706,"d":"8.71"},{"v":11.71766,"d":"11.72"},0,0,0,0,"inf","inf",{"v":1.14308317090955e-6,"d":"0.00"},{"v":0.000432585537491081,"d":"0.00"},"up","yes"]
[65763,0,"chr15","+",68578969,68727803,"ENST00000566799",12,3566,"ENSG00000103647","CORO2B","GO:0003093(regulation of glomerular filtration);GO:0003779(actin binding);GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0005856(cytoskeleton);GO:0005925(focal adhesion);GO:0010812(negative regulation of cell-substrate adhesion);GO:0015629(actin cytoskeleton);GO:0016020(membrane);GO:0017166(vinculin binding);GO:0030036(actin cytoskeleton organization);GO:0032956(regulation of actin cytoskeleton organization);GO:0048041(focal adhesion assembly);GO:0051015(actin filament binding);GO:0051497(negative regulation of stress fiber assembly);GO:0080135(regulation of cellular response to stress);GO:1904950(negative regulation of establishment of protein localization);GO:1904951(positive regulation of establishment of protein localization);GO:1990147(talin binding)","NA","NA","NA","coronin 2B [Source:HGNC Symbol;Acc:HGNC:2256]",0,0,0,{"v":0.601583,"d":"0.60"},{"v":0.27789,"d":"0.28"},{"v":0.525885,"d":"0.53"},"-inf","-inf",{"v":1.17521978562452e-6,"d":"0.00"},{"v":0.00044016221455401,"d":"0.00"},"down","yes"]
[90141,0,"chr17","+",75205707,75235757,"ENST00000579324",18,2010,"ENSG00000125450","NUP85","GO:0000775(chromosome, centromeric region);GO:0000776(kinetochore);GO:0000777(condensed chromosome kinetochore);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005635(nuclear envelope);GO:0005643(nuclear pore);GO:0005694(chromosome);GO:0005737(cytoplasm);GO:0005819(spindle);GO:0005829(cytosol);GO:0005856(cytoskeleton);GO:0006110(regulation of glycolytic process);GO:0006406(mRNA export from nucleus);GO:0006409(tRNA export from nucleus);GO:0006606(protein import into nucleus);GO:0006913(nucleocytoplasmic transport);GO:0006935(chemotaxis);GO:0015031(protein transport);GO:0016020(membrane);GO:0016032(viral process);GO:0016925(protein sumoylation);GO:0017056(structural constituent of nuclear pore);GO:0019083(viral transcription);GO:0030032(lamellipodium assembly);GO:0031080(nuclear pore outer ring);GO:0031965(nuclear membrane);GO:0043657(host cell);GO:0045893(positive regulation of transcription, DNA-templated);GO:0048246(macrophage chemotaxis);GO:0051028(mRNA transport);GO:0060964(regulation of gene silencing by miRNA);GO:0072006(nephron development);GO:0075733(intracellular transport of virus);GO:1900034(regulation of cellular response to heat)","03013(RNA transport)","K14304","NA","nucleoporin 85 [Source:HGNC Symbol;Acc:HGNC:8734]",{"v":1.199287,"d":"1.20"},{"v":1.127595,"d":"1.13"},{"v":0.389644,"d":"0.39"},0,0,0,"inf","inf",{"v":1.19109415884741e-6,"d":"0.00"},{"v":0.000441555620315575,"d":"0.00"},"up","yes"]
[46417,0,"chr12","-",91146166,91179513,"ENST00000546391",5,716,"ENSG00000011465","DCN","GO:0001822(kidney development);GO:0001890(placenta development);GO:0003723(RNA binding);GO:0005515(protein binding);GO:0005518(collagen binding);GO:0005539(glycosaminoglycan binding);GO:0005576(extracellular region);GO:0005589(collagen type VI trimer);GO:0005615(extracellular space);GO:0005796(Golgi lumen);GO:0007519(skeletal muscle tissue development);GO:0007568(aging);GO:0009612(response to mechanical stimulus);GO:0009887(animal organ morphogenesis);GO:0010508(positive regulation of autophagy);GO:0010596(negative regulation of endothelial cell migration);GO:0014068(positive regulation of phosphatidylinositol 3-kinase signaling);GO:0016239(positive regulation of macroautophagy);GO:0016525(negative regulation of angiogenesis);GO:0019800(peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan);GO:0030021(extracellular matrix structural constituent conferring compression resistance);GO:0030198(extracellular matrix organization);GO:0030206(chondroitin sulfate biosynthetic process);GO:0030207(chondroitin sulfate catabolic process);GO:0030208(dermatan sulfate biosynthetic process);GO:0031012(extracellular matrix);GO:0032496(response to lipopolysaccharide);GO:0042060(wound healing);GO:0043202(lysosomal lumen);GO:0045944(positive regulation of transcription by RNA polymerase II);GO:0047485(protein N-terminus binding);GO:0050840(extracellular matrix binding);GO:0051901(positive regulation of mitochondrial depolarization);GO:0062023(collagen-containing extracellular matrix);GO:0090141(positive regulation of mitochondrial fission);GO:1900747(negative regulation of vascular endothelial growth factor signaling pathway)","04350(TGF-beta signaling pathway);05205(Proteoglycans in cancer)","NA","NA","decorin [Source:HGNC Symbol;Acc:HGNC:2705]",{"v":3.192665,"d":"3.19"},{"v":1.635838,"d":"1.64"},{"v":2.084646,"d":"2.08"},0,0,0,"inf","inf",{"v":1.32846252537659e-6,"d":"0.00"},{"v":0.000487505490373044,"d":"0.00"},"up","yes"]
[66222,0,"chr15","+",73684438,73713580,"ENST00000560928",10,2181,"ENSG00000103855","CD276","GO:0005102(signaling receptor binding);GO:0005515(protein binding);GO:0006955(immune response);GO:0008283(cell population proliferation);GO:0009897(external side of plasma membrane);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0042102(positive regulation of T cell proliferation);GO:0042110(T cell activation);GO:0045078(positive regulation of interferon-gamma biosynthetic process);GO:0050776(regulation of immune response);GO:0050852(T cell receptor signaling pathway)","04514(Cell adhesion molecules (CAMs))","K06746","NA","CD276 molecule [Source:HGNC Symbol;Acc:HGNC:19137]",{"v":11.141171,"d":"11.14"},0,{"v":13.320064,"d":"13.32"},0,0,0,"inf","inf",{"v":1.46933477567522e-6,"d":"0.00"},{"v":0.000533809324002807,"d":"0.00"},"up","yes"]
[145944,0,"chr3","+",158802156,158829715,"ENST00000471500",16,2097,"ENSG00000118855","MFSD1","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0055085(transmembrane transport)","NA","NA","NA","major facilitator superfamily domain containing 1 [Source:HGNC Symbol;Acc:HGNC:25874]",0,0,0,0,{"v":14.020334,"d":"14.02"},{"v":11.150594,"d":"11.15"},"-inf","-inf",{"v":1.49284955578065e-6,"d":"0.00"},{"v":0.000534686840125993,"d":"0.00"},"down","yes"]
[204070,0,"chrX","+",71118695,71142454,"ENST00000374102",45,6827,"ENSG00000184634","MED12","GO:0000151(ubiquitin ligase complex);GO:0000980(RNA polymerase II distal enhancer sequence-specific DNA binding);GO:0001756(somitogenesis);GO:0001843(neural tube closure);GO:0003682(chromatin binding);GO:0003712(transcription coregulator activity);GO:0003713(transcription coactivator activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0006357(regulation of transcription by RNA polymerase II);GO:0006367(transcription initiation from RNA polymerase II promoter);GO:0007492(endoderm development);GO:0007507(heart development);GO:0008013(beta-catenin binding);GO:0008022(protein C-terminus binding);GO:0008134(transcription factor binding);GO:0014003(oligodendrocyte development);GO:0014044(Schwann cell development);GO:0016020(membrane);GO:0016567(protein ubiquitination);GO:0016592(mediator complex);GO:0019827(stem cell population maintenance);GO:0019904(protein domain specific binding);GO:0021510(spinal cord development);GO:0021915(neural tube development);GO:0030374(nuclear receptor transcription coactivator activity);GO:0036342(post-anal tail morphogenesis);GO:0042809(vitamin D receptor binding);GO:0045893(positive regulation of transcription, DNA-templated);GO:0045944(positive regulation of transcription by RNA polymerase II);GO:0046966(thyroid hormone receptor binding);GO:0048568(embryonic organ development);GO:0048702(embryonic neurocranium morphogenesis);GO:0060070(canonical Wnt signaling pathway);GO:0060071(Wnt signaling pathway, planar cell polarity pathway);GO:0061630(ubiquitin protein ligase activity);GO:0090245(axis elongation involved in somitogenesis);GO:1990403(embryonic brain development)","04919(Thyroid hormone signaling pathway)","K15162","NA","mediator complex subunit 12 [Source:HGNC Symbol;Acc:HGNC:11957]",{"v":0.043212,"d":"0.04"},0,{"v":0.000271,"d":"0.00"},{"v":4.275946,"d":"4.28"},{"v":3.635329,"d":"3.64"},{"v":1.388432,"d":"1.39"},{"v":0.00467573870875717,"d":"0.00"},{"v":-7.7405899737217,"d":"-7.74"},{"v":1.50630587063733e-6,"d":"0.00"},{"v":0.000534686840125993,"d":"0.00"},"down","yes"]
[135064,0,"chr22","-",41525804,41544489,"ENST00000396504",7,4176,"ENSG00000100413","POLR3H","GO:0001056(RNA polymerase III activity);GO:0002376(immune system process);GO:0003677(DNA binding);GO:0003899(DNA-directed 5'-3' RNA polymerase activity);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005666(RNA polymerase III complex);GO:0005813(centrosome);GO:0005829(cytosol);GO:0006139(nucleobase-containing compound metabolic process);GO:0006351(transcription, DNA-templated);GO:0006383(transcription by RNA polymerase III);GO:0006384(transcription initiation from RNA polymerase III promoter);GO:0032481(positive regulation of type I interferon production);GO:0043231(intracellular membrane-bounded organelle);GO:0045087(innate immune response);GO:0051607(defense response to virus)","03020(RNA polymerase);04623(Cytosolic DNA-sensing pathway)","K03022","NA","RNA polymerase III subunit H [Source:HGNC Symbol;Acc:HGNC:30349]",0,0,0,{"v":6.281936,"d":"6.28"},0,{"v":5.501751,"d":"5.50"},"-inf","-inf",{"v":1.51590268464017e-6,"d":"0.00"},{"v":0.000534686840125993,"d":"0.00"},"down","yes"]
[39519,0,"chr12","-",7080421,7091892,"ENST00000536053",11,2347,"ENSG00000159403","C1R","GO:0002376(immune system process);GO:0004252(serine-type endopeptidase activity);GO:0005509(calcium ion binding);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0005615(extracellular space);GO:0006508(proteolysis);GO:0006955(immune response);GO:0006956(complement activation);GO:0006958(complement activation, classical pathway);GO:0008233(peptidase activity);GO:0008236(serine-type peptidase activity);GO:0016787(hydrolase activity);GO:0030449(regulation of complement activation);GO:0031638(zymogen activation);GO:0045087(innate immune response);GO:0070062(extracellular exosome);GO:0072562(blood microparticle)","04145(Phagosome);04610(Complement and coagulation cascades);05133(Pertussis);05150(Staphylococcus aureus infection);05322(Systemic lupus erythematosus)","NA","NA","complement C1r [Source:HGNC Symbol;Acc:HGNC:1246]",{"v":476.274048,"d":"476.27"},{"v":545.549988,"d":"545.55"},{"v":364.576202,"d":"364.58"},{"v":61.130077,"d":"61.13"},{"v":42.543945,"d":"42.54"},{"v":33.054592,"d":"33.05"},{"v":10.1397958879332,"d":"10.14"},{"v":3.34195670635777,"d":"3.34"},{"v":1.55580497814207e-6,"d":"0.00"},{"v":0.000543484565922128,"d":"0.00"},"up","yes"]
[76059,0,"chr16","-",66802912,66830955,"ENST00000394074",19,1654,"ENSG00000159593","NAE1","GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0006915(apoptotic process);GO:0007049(cell cycle);GO:0007165(signal transduction);GO:0008641(ubiquitin-like modifier activating enzyme activity);GO:0016020(membrane);GO:0019781(NEDD8 activating enzyme activity);GO:0031625(ubiquitin protein ligase binding);GO:0032446(protein modification by small protein conjugation);GO:0032991(protein-containing complex);GO:0033314(mitotic DNA replication checkpoint);GO:0042981(regulation of apoptotic process);GO:0043523(regulation of neuron apoptotic process);GO:0043687(post-translational protein modification);GO:0045116(protein neddylation);GO:0046982(protein heterodimerization activity);GO:0051402(neuron apoptotic process)","05010(Alzheimer disease)","K04532","NA","NEDD8 activating enzyme E1 subunit 1 [Source:HGNC Symbol;Acc:HGNC:621]",{"v":15.10039,"d":"15.10"},{"v":15.61319,"d":"15.61"},0,0,0,0,"inf","inf",{"v":1.68399798384586e-6,"d":"0.00"},{"v":0.000582663302410668,"d":"0.00"},"up","yes"]
[43034,0,"chr12","+",51590926,51766251,"ENST00000550891",16,3253,"ENSG00000196876","SCN8A","GO:0000166(nucleotide binding);GO:0001518(voltage-gated sodium channel complex);GO:0005216(ion channel activity);GO:0005244(voltage-gated ion channel activity);GO:0005248(voltage-gated sodium channel activity);GO:0005272(sodium channel activity);GO:0005515(protein binding);GO:0005524(ATP binding);GO:0005886(plasma membrane);GO:0006811(ion transport);GO:0006814(sodium ion transport);GO:0007399(nervous system development);GO:0007422(peripheral nervous system development);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0019228(neuronal action potential);GO:0030018(Z disc);GO:0030424(axon);GO:0031410(cytoplasmic vesicle);GO:0033268(node of Ranvier);GO:0034220(ion transmembrane transport);GO:0034765(regulation of ion transmembrane transport);GO:0035725(sodium ion transmembrane transport);GO:0042552(myelination);GO:0043194(axon initial segment);GO:0055085(transmembrane transport);GO:0086010(membrane depolarization during action potential)","NA","K04840","NA","sodium voltage-gated channel alpha subunit 8 [Source:HGNC Symbol;Acc:HGNC:10596]",0,0,0,{"v":0.443071,"d":"0.44"},{"v":0.54214,"d":"0.54"},{"v":0.401399,"d":"0.40"},"-inf","-inf",{"v":1.87783484993731e-6,"d":"0.00"},{"v":0.000643601321681343,"d":"0.00"},"down","yes"]
[54194,0,"chr14","-",21090082,21104722,"ENST00000451119",5,2918,"ENSG00000165804","ZNF219","GO:0000122(negative regulation of transcription by RNA polymerase II);GO:0000978(RNA polymerase II proximal promoter sequence-specific DNA binding);GO:0000981(DNA-binding transcription factor activity, RNA polymerase II-specific);GO:0001227(DNA-binding transcription repressor activity, RNA polymerase II-specific);GO:0001505(regulation of neurotransmitter levels);GO:0003676(nucleic acid binding);GO:0003677(DNA binding);GO:0003700(DNA-binding transcription factor activity);GO:0004969(histamine receptor activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0007186(G protein-coupled receptor signaling pathway);GO:0016021(integral component of membrane);GO:0032332(positive regulation of chondrocyte differentiation);GO:0045892(negative regulation of transcription, DNA-templated);GO:0045944(positive regulation of transcription by RNA polymerase II);GO:0046872(metal ion binding);GO:0060174(limb bud formation)","NA","NA","NA","zinc finger protein 219 [Source:HGNC Symbol;Acc:HGNC:13011]",0,0,0,{"v":1.69389,"d":"1.69"},{"v":3.955529,"d":"3.96"},{"v":0.011935,"d":"0.01"},"-inf","-inf",{"v":1.99093944584864e-6,"d":"0.00"},{"v":0.000675989066053095,"d":"0.00"},"down","yes"]
[174362,0,"chr6","-",137197497,137219136,"ENST00000646036",8,2183,"ENSG00000027697","IFNGR1","GO:0004896(cytokine receptor activity);GO:0004906(interferon-gamma receptor activity);GO:0005515(protein binding);GO:0005886(plasma membrane);GO:0005887(integral component of plasma membrane);GO:0007165(signal transduction);GO:0009615(response to virus);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0019221(cytokine-mediated signaling pathway);GO:0019955(cytokine binding);GO:0060333(interferon-gamma-mediated signaling pathway);GO:0060334(regulation of interferon-gamma-mediated signaling pathway)","04060(Cytokine-cytokine receptor interaction);04066(HIF-1 signaling pathway);04217(Necroptosis);04380(Osteoclast differentiation);04630(Jak-STAT signaling pathway);04650(Natural killer cell mediated cytotoxicity);04658(Th1 and Th2 cell differentiation);04659(Th17 cell differentiation);05132(Salmonella infection);05140(Leishmaniasis);05142(Chagas disease (American trypanosomiasis));05145(Toxoplasmosis);05152(Tuberculosis);05164(Influenza A);05167(Kaposi sarcoma-associated herpesvirus infection);05168(Herpes simplex virus 1 infection);05200(Pathways in cancer);05321(Inflammatory bowel disease (IBD))","K05132","NA","interferon gamma receptor 1 [Source:HGNC Symbol;Acc:HGNC:5439]",{"v":32.678005,"d":"32.68"},{"v":41.911137,"d":"41.91"},0,0,0,{"v":0.012254,"d":"0.01"},{"v":6086.92198465807,"d":"6086.92"},{"v":12.5714971597487,"d":"12.57"},{"v":2.07710729713758e-6,"d":"0.00"},{"v":0.000698715815787113,"d":"0.00"},"up","yes"]
[163917,0,"chr5","-",142592178,142621342,"ENST00000359370",4,3660,"ENSG00000113578","FGF1","GO:0000165(MAPK cascade);GO:0000187(activation of MAPK activity);GO:0001525(angiogenesis);GO:0001759(organ induction);GO:0001934(positive regulation of protein phosphorylation);GO:0005104(fibroblast growth factor receptor binding);GO:0005178(integrin binding);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0005615(extracellular space);GO:0005634(nucleus);GO:0005730(nucleolus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005938(cell cortex);GO:0007165(signal transduction);GO:0007275(multicellular organism development);GO:0008083(growth factor activity);GO:0008201(heparin binding);GO:0008283(cell population proliferation);GO:0008284(positive regulation of cell population proliferation);GO:0008543(fibroblast growth factor receptor signaling pathway);GO:0009653(anatomical structure morphogenesis);GO:0010469(regulation of signaling receptor activity);GO:0010595(positive regulation of endothelial cell migration);GO:0030154(cell differentiation);GO:0030324(lung development);GO:0030335(positive regulation of cell migration);GO:0030544(Hsp70 protein binding);GO:0031012(extracellular matrix);GO:0032148(activation of protein kinase B activity);GO:0034605(cellular response to heat);GO:0043406(positive regulation of MAP kinase activity);GO:0044548(S100 protein binding);GO:0045542(positive regulation of cholesterol biosynthetic process);GO:0045766(positive regulation of angiogenesis);GO:0045944(positive regulation of transcription by RNA polymerase II);GO:0050679(positive regulation of epithelial cell proliferation);GO:0051781(positive regulation of cell division);GO:0051897(positive regulation of protein kinase B signaling);GO:0060681(branch elongation involved in ureteric bud branching);GO:0072163(mesonephric epithelium development);GO:1901509(regulation of endothelial tube morphogenesis);GO:1902533(positive regulation of intracellular signal transduction);GO:1903672(positive regulation of sprouting angiogenesis);GO:2000544(regulation of endothelial cell chemotaxis to fibroblast growth factor)","04010(MAPK signaling pathway);04014(Ras signaling pathway);04015(Rap1 signaling pathway);04151(PI3K-Akt signaling pathway);04390(Hippo signaling pathway);04810(Regulation of actin cytoskeleton);05200(Pathways in cancer);05218(Melanoma);05224(Breast cancer);05226(Gastric cancer)","K18496","NA","fibroblast growth factor 1 [Source:HGNC Symbol;Acc:HGNC:3665]",0,0,0,{"v":0.291828,"d":"0.29"},{"v":0.515841,"d":"0.52"},{"v":0.411568,"d":"0.41"},"-inf","-inf",{"v":2.13029666499564e-6,"d":"0.00"},{"v":0.000710033741644877,"d":"0.00"},"down","yes"]
[65470,0,"chr15","-",65579147,65611242,"ENST00000420799",11,1741,"ENSG00000138614","INTS14","GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0032039(integrator complex);GO:0034472(snRNA 3'-end processing);GO:0042795(snRNA transcription by RNA polymerase II)","NA","NA","NA","integrator complex subunit 14 [Source:HGNC Symbol;Acc:HGNC:25372]",0,0,0,{"v":0.926914,"d":"0.93"},{"v":6.504915,"d":"6.50"},{"v":0.050436,"d":"0.05"},"-inf","-inf",{"v":2.1650461569002e-6,"d":"0.00"},{"v":0.000714190213719392,"d":"0.00"},"down","yes"]
[73613,0,"chr16","+",30064185,30070257,"ENST00000569545",11,1359,"ENSG00000149925","ALDOA","GO:0002576(platelet degranulation);GO:0003723(RNA binding);GO:0003779(actin binding);GO:0003824(catalytic activity);GO:0004332(fructose-bisphosphate aldolase activity);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0005615(extracellular space);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0006000(fructose metabolic process);GO:0006094(gluconeogenesis);GO:0006096(glycolytic process);GO:0006754(ATP biosynthetic process);GO:0006941(striated muscle contraction);GO:0007015(actin filament organization);GO:0007339(binding of sperm to zona pellucida);GO:0008092(cytoskeletal protein binding);GO:0008360(regulation of cell shape);GO:0015629(actin cytoskeleton);GO:0015631(tubulin binding);GO:0016020(membrane);GO:0016829(lyase activity);GO:0030388(fructose 1,6-bisphosphate metabolic process);GO:0031093(platelet alpha granule lumen);GO:0031430(M band);GO:0031674(I band);GO:0034774(secretory granule lumen);GO:0042802(identical protein binding);GO:0043312(neutrophil degranulation);GO:0045296(cadherin binding);GO:0046716(muscle cell cellular homeostasis);GO:0051289(protein homotetramerization);GO:0061621(canonical glycolysis);GO:0061827(sperm head);GO:0070061(fructose binding);GO:0070062(extracellular exosome);GO:1904724(tertiary granule lumen);GO:1904813(ficolin-1-rich granule lumen)","00010(Glycolysis / Gluconeogenesis);00030(Pentose phosphate pathway);00051(Fructose and mannose metabolism);04066(HIF-1 signaling pathway)","NA","NA","aldolase, fructose-bisphosphate A [Source:HGNC Symbol;Acc:HGNC:414]",{"v":27.222902,"d":"27.22"},{"v":24.334223,"d":"24.33"},0,0,{"v":0.001749,"d":"0.00"},0,{"v":29478.0588907947,"d":"29478.06"},{"v":14.8473539066681,"d":"14.85"},{"v":2.18208405512944e-6,"d":"0.00"},{"v":0.000714190213719392,"d":"0.00"},"up","yes"]
[65546,0,"chr15","+",66295097,66333728,"ENST00000530537",16,3260,"ENSG00000166938","DIS3L","GO:0000175(3'-5'-exoribonuclease activity);GO:0000176(nuclear exosome (RNase complex));GO:0000177(cytoplasmic exosome (RNase complex));GO:0000178(exosome (RNase complex));GO:0003723(RNA binding);GO:0004518(nuclease activity);GO:0004519(endonuclease activity);GO:0004527(exonuclease activity);GO:0004540(ribonuclease activity);GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0005813(centrosome);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0016075(rRNA catabolic process);GO:0016787(hydrolase activity);GO:0019899(enzyme binding);GO:0090503(RNA phosphodiester bond hydrolysis, exonucleolytic)","03018(RNA degradation)","K18681","EC:3.1.13.-","DIS3 like exosome 3'-5' exoribonuclease [Source:HGNC Symbol;Acc:HGNC:28698]",0,0,0,{"v":8.280388,"d":"8.28"},0,{"v":5.157617,"d":"5.16"},"-inf","-inf",{"v":2.28519842434688e-6,"d":"0.00"},{"v":0.00074126123889752,"d":"0.00"},"down","yes"]
[36979,0,"chr11","+",118631916,118658025,"ENST00000527898",13,2921,"ENSG00000019144","PHLDB1","GO:0005515(protein binding);GO:0010470(regulation of gastrulation);GO:0010717(regulation of epithelial to mesenchymal transition);GO:0045180(basal cortex);GO:0070507(regulation of microtubule cytoskeleton organization);GO:1904261(positive regulation of basement membrane assembly involved in embryonic body morphogenesis)","NA","NA","NA","pleckstrin homology like domain family B member 1 [Source:HGNC Symbol;Acc:HGNC:23697]",0,0,0,{"v":6.01122,"d":"6.01"},0,{"v":8.43855,"d":"8.44"},"-inf","-inf",{"v":2.36222531739482e-6,"d":"0.00"},{"v":0.000759465891866849,"d":"0.00"},"down","yes"]
[12987,0,"chr1","-",160289293,160343247,"ENST00000650154",31,4458,"ENSG00000122218","COPA","GO:0000139(Golgi membrane);GO:0005179(hormone activity);GO:0005198(structural molecule activity);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0005615(extracellular space);GO:0005737(cytoplasm);GO:0005789(endoplasmic reticulum membrane);GO:0005794(Golgi apparatus);GO:0005829(cytosol);GO:0006886(intracellular protein transport);GO:0006888(endoplasmic reticulum to Golgi vesicle-mediated transport);GO:0006890(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum);GO:0006891(intra-Golgi vesicle-mediated transport);GO:0010469(regulation of signaling receptor activity);GO:0015031(protein transport);GO:0016020(membrane);GO:0016192(vesicle-mediated transport);GO:0030117(membrane coat);GO:0030126(COPI vesicle coat);GO:0030133(transport vesicle);GO:0030157(pancreatic juice secretion);GO:0030663(COPI-coated vesicle membrane);GO:0031410(cytoplasmic vesicle);GO:0070062(extracellular exosome)","NA","NA","NA","coatomer protein complex subunit alpha [Source:HGNC Symbol;Acc:HGNC:2230]",{"v":0.454703,"d":"0.45"},{"v":26.556618,"d":"26.56"},0,0,0,0,"inf","inf",{"v":2.41154561435573e-6,"d":"0.00"},{"v":0.000768521510259155,"d":"0.00"},"up","yes"]
[65390,0,"chr15","-",65054228,65067943,"ENST00000421977",4,1523,"ENSG00000103710","RASL12","GO:0000166(nucleotide binding);GO:0003924(GTPase activity);GO:0005525(GTP binding);GO:0007165(signal transduction);GO:0016020(membrane)","NA","K07854","NA","RAS like family 12 [Source:HGNC Symbol;Acc:HGNC:30289]",{"v":0.941543,"d":"0.94"},{"v":1.108774,"d":"1.11"},{"v":0.826773,"d":"0.83"},0,0,0,"inf","inf",{"v":2.45530803890217e-6,"d":"0.00"},{"v":0.000775663835246223,"d":"0.00"},"up","yes"]
[152433,0,"chr4","-",77713387,77819368,"ENST00000649644",12,8843,"ENSG00000138767","CNOT6L","GO:0000288(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay);GO:0000289(nuclear-transcribed mRNA poly(A) tail shortening);GO:0004518(nuclease activity);GO:0004527(exonuclease activity);GO:0004535(poly(A)-specific ribonuclease activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0006397(mRNA processing);GO:0006417(regulation of translation);GO:0006977(DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest);GO:0008284(positive regulation of cell population proliferation);GO:0010606(positive regulation of cytoplasmic mRNA processing body assembly);GO:0016787(hydrolase activity);GO:0030014(CCR4-NOT complex);GO:0031047(gene silencing by RNA);GO:0046872(metal ion binding);GO:0061157(mRNA destabilization);GO:0090305(nucleic acid phosphodiester bond hydrolysis);GO:0090503(RNA phosphodiester bond hydrolysis, exonucleolytic)","03018(RNA degradation)","K12603","EC:3.1.13.4","CCR4-NOT transcription complex subunit 6 like [Source:HGNC Symbol;Acc:HGNC:18042]",{"v":0.436522,"d":"0.44"},{"v":0.333018,"d":"0.33"},{"v":0.379039,"d":"0.38"},{"v":0.005349,"d":"0.01"},0,0,{"v":214.727799588708,"d":"214.73"},{"v":7.74636517059641,"d":"7.75"},{"v":2.5594071388669e-6,"d":"0.00"},{"v":0.000801579839267538,"d":"0.00"},"up","yes"]
[1721,0,"chr1","+",12277121,12510361,"ENST00000011700",52,10969,"ENSG00000048707","VPS13D","GO:0005515(protein binding);GO:0005623(cell);GO:0006623(protein targeting to vacuole);GO:0007005(mitochondrion organization);GO:0019898(extrinsic component of membrane);GO:0045053(protein retention in Golgi apparatus);GO:0070062(extracellular exosome);GO:1901526(positive regulation of mitophagy)","NA","K19527","NA","vacuolar protein sorting 13 homolog D [Source:HGNC Symbol;Acc:HGNC:23595]",0,0,0,{"v":3.072581,"d":"3.07"},{"v":1.133011,"d":"1.13"},0,"-inf","-inf",{"v":2.65987606160949e-6,"d":"0.00"},{"v":0.000825925618104896,"d":"0.00"},"down","yes"]
[110565,0,"chr2","-",26190922,26244604,"ENST00000643063",21,2748,"ENSG00000084754","HADHA","GO:0000062(fatty-acyl-CoA binding);GO:0003824(catalytic activity);GO:0003857(3-hydroxyacyl-CoA dehydrogenase activity);GO:0003985(acetyl-CoA C-acetyltransferase activity);GO:0003988(acetyl-CoA C-acyltransferase activity);GO:0004300(enoyl-CoA hydratase activity);GO:0005515(protein binding);GO:0005739(mitochondrion);GO:0005743(mitochondrial inner membrane);GO:0006629(lipid metabolic process);GO:0006631(fatty acid metabolic process);GO:0006635(fatty acid beta-oxidation);GO:0008152(metabolic process);GO:0016491(oxidoreductase activity);GO:0016507(mitochondrial fatty acid beta-oxidation multienzyme complex);GO:0016508(long-chain-enoyl-CoA hydratase activity);GO:0016509(long-chain-3-hydroxyacyl-CoA dehydrogenase activity);GO:0016829(lyase activity);GO:0032868(response to insulin);GO:0035965(cardiolipin acyl-chain remodeling);GO:0042493(response to drug);GO:0042645(mitochondrial nucleoid);GO:0044877(protein-containing complex binding);GO:0051287(NAD binding);GO:0055114(oxidation-reduction process)","00062(Fatty acid elongation);00071(Fatty acid degradation);00280(Valine, leucine and isoleucine degradation);00310(Lysine degradation);00380(Tryptophan metabolism);00410(beta-Alanine metabolism);00640(Propanoate metabolism);00650(Butanoate metabolism)","K07515","1.1.1.211;EC:4.2.1.17","hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha [Source:HGNC Symbol;Acc:HGNC:4801]",0,0,0,{"v":0.390653,"d":"0.39"},{"v":63.450199,"d":"63.45"},0,"-inf","-inf",{"v":2.79303038659202e-6,"d":"0.00"},{"v":0.000855042317947931,"d":"0.00"},"down","yes"]
[7821,0,"chr1","+",84144271,84238498,"ENST00000370685",10,4481,"ENSG00000142875","PRKACB","GO:0000166(nucleotide binding);GO:0000287(magnesium ion binding);GO:0001843(neural tube closure);GO:0002223(stimulatory C-type lectin receptor signaling pathway);GO:0003091(renal water homeostasis);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0004691(cAMP-dependent protein kinase activity);GO:0005515(protein binding);GO:0005524(ATP binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0005813(centrosome);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0005952(cAMP-dependent protein kinase complex);GO:0006468(protein phosphorylation);GO:0007165(signal transduction);GO:0007186(G protein-coupled receptor signaling pathway);GO:0007188(adenylate cyclase-modulating G protein-coupled receptor signaling pathway);GO:0007596(blood coagulation);GO:0016020(membrane);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0016740(transferase activity);GO:0031625(ubiquitin protein ligase binding);GO:0034199(activation of protein kinase A activity);GO:0034237(protein kinase A regulatory subunit binding);GO:0034380(high-density lipoprotein particle assembly);GO:0045171(intercellular bridge);GO:0048471(perinuclear region of cytoplasm);GO:0051447(negative regulation of meiotic cell cycle);GO:0070062(extracellular exosome);GO:0070613(regulation of protein processing);GO:0071377(cellular response to glucagon stimulus);GO:0097338(response to clozapine);GO:0097546(ciliary base);GO:1901621(negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning)","01522(Endocrine resistance);04010(MAPK signaling pathway);04014(Ras signaling pathway);04020(Calcium signaling pathway);04024(cAMP signaling pathway);04062(Chemokine signaling pathway);04114(Oocyte meiosis);04140(Autophagy - animal);04211(Longevity regulating pathway);04213(Longevity regulating pathway - multiple species);04261(Adrenergic signaling in cardiomyocytes);04270(Vascular smooth muscle contraction);04310(Wnt signaling pathway);04340(Hedgehog signaling pathway);04371(Apelin signaling pathway);04530(Tight junction);04540(Gap junction);04611(Platelet activation);04713(Circadian entrainment);04714(Thermogenesis);04720(Long-term potentiation);04723(Retrograde endocannabinoid signaling);04724(Glutamatergic synapse);04725(Cholinergic synapse);04726(Serotonergic synapse);04727(GABAergic synapse);04728(Dopaminergic synapse);04740(Olfactory transduction);04742(Taste transduction);04750(Inflammatory mediator regulation of TRP channels);04910(Insulin signaling pathway);04911(Insulin secretion);04912(GnRH signaling pathway);04913(Ovarian steroidogenesis);04914(Progesterone-mediated oocyte maturation);04915(Estrogen signaling pathway);04916(Melanogenesis);04918(Thyroid hormone synthesis);04919(Thyroid hormone signaling pathway);04921(Oxytocin signaling pathway);04922(Glucagon signaling pathway);04923(Regulation of lipolysis in adipocytes);04924(Renin secretion);04925(Aldosterone synthesis and secretion);04926(Relaxin signaling pathway);04927(Cortisol synthesis and secretion);04928(Parathyroid hormone synthesis, secretion and action);04934(Cushing syndrome);04961(Endocrine and other factor-regulated calcium reabsorption);04962(Vasopressin-regulated water reabsorption);04970(Salivary secretion);04971(Gastric acid secretion);04976(Bile secretion);05012(Parkinson disease);05020(Prion diseases);05030(Cocaine addiction);05031(Amphetamine addiction);05032(Morphine addiction);05110(Vibrio cholerae infection);05146(Amoebiasis);05163(Human cytomegalovirus infection);05165(Human papillomavirus infection);05166(Human T-cell leukemia virus 1 infection);05200(Pathways in cancer);05203(Viral carcinogenesis);05205(Proteoglycans in cancer);05414(Dilated cardiomyopathy (DCM))","NA","NA","protein kinase cAMP-activated catalytic subunit beta [Source:HGNC Symbol;Acc:HGNC:9381]",0,0,0,{"v":4.839232,"d":"4.84"},{"v":0.011577,"d":"0.01"},{"v":0.254563,"d":"0.25"},"-inf","-inf",{"v":2.80071664838436e-6,"d":"0.00"},{"v":0.000855042317947931,"d":"0.00"},"down","yes"]
[42782,0,"chr12","-",50175788,50222348,"ENST00000552823",8,3254,"ENSG00000050405","LIMA1","GO:0001725(stress fiber);GO:0001726(ruffle);GO:0003779(actin binding);GO:0003785(actin monomer binding);GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005856(cytoskeleton);GO:0005886(plasma membrane);GO:0005903(brush border);GO:0005925(focal adhesion);GO:0006629(lipid metabolic process);GO:0008202(steroid metabolic process);GO:0008203(cholesterol metabolic process);GO:0015629(actin cytoskeleton);GO:0016020(membrane);GO:0016477(cell migration);GO:0030054(cell junction);GO:0030299(intestinal cholesterol absorption);GO:0030835(negative regulation of actin filament depolymerization);GO:0031526(brush border membrane);GO:0031529(ruffle organization);GO:0032154(cleavage furrow);GO:0042632(cholesterol homeostasis);GO:0045296(cadherin binding);GO:0046872(metal ion binding);GO:0051015(actin filament binding);GO:0051017(actin filament bundle assembly)","NA","K23026","NA","LIM domain and actin binding 1 [Source:HGNC Symbol;Acc:HGNC:24636]",{"v":1.8e-5,"d":"0.00"},{"v":0.000372,"d":"0.00"},{"v":7.5e-5,"d":"0.00"},{"v":5.189887,"d":"5.19"},{"v":6.042465,"d":"6.04"},{"v":8.6e-5,"d":"0.00"},{"v":4.13979583061131e-5,"d":"0.00"},{"v":-14.5600808568156,"d":"-14.56"},{"v":2.96126301717212e-6,"d":"0.00"},{"v":0.000896522378448858,"d":"0.00"},"down","yes"]
[153619,0,"chr4","-",101023431,101347471,"ENST00000323055",12,4519,"ENSG00000138814","PPP3CA","GO:0000082(G1/S transition of mitotic cell cycle);GO:0001975(response to amphetamine);GO:0004721(phosphoprotein phosphatase activity);GO:0004722(protein serine/threonine phosphatase activity);GO:0004723(calcium-dependent protein serine/threonine phosphatase activity);GO:0005509(calcium ion binding);GO:0005515(protein binding);GO:0005516(calmodulin binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0005739(mitochondrion);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0005955(calcineurin complex);GO:0006470(protein dephosphorylation);GO:0006606(protein import into nucleus);GO:0006816(calcium ion transport);GO:0007223(Wnt signaling pathway, calcium modulating pathway);GO:0007420(brain development);GO:0007568(aging);GO:0008144(drug binding);GO:0009898(cytoplasmic side of plasma membrane);GO:0010613(positive regulation of cardiac muscle hypertrophy);GO:0010628(positive regulation of gene expression);GO:0010629(negative regulation of gene expression);GO:0014883(transition between fast and slow fiber);GO:0014898(cardiac muscle hypertrophy in response to stress);GO:0016018(cyclosporin A binding);GO:0016020(membrane);GO:0016311(dephosphorylation);GO:0016787(hydrolase activity);GO:0019722(calcium-mediated signaling);GO:0019899(enzyme binding);GO:0030018(Z disc);GO:0030335(positive regulation of cell migration);GO:0033173(calcineurin-NFAT signaling cascade);GO:0033192(calmodulin-dependent protein phosphatase activity);GO:0033555(multicellular organismal response to stress);GO:0035562(negative regulation of chromatin binding);GO:0035690(cellular response to drug);GO:0036057(slit diaphragm);GO:0038095(Fc-epsilon receptor signaling pathway);GO:0042110(T cell activation);GO:0042383(sarcolemma);GO:0042995(cell projection);GO:0043197(dendritic spine);GO:0043403(skeletal muscle tissue regeneration);GO:0045202(synapse);GO:0045785(positive regulation of cell adhesion);GO:0045807(positive regulation of endocytosis);GO:0045944(positive regulation of transcription by RNA polymerase II);GO:0046676(negative regulation of insulin secretion);GO:0046872(metal ion binding);GO:0046982(protein heterodimerization activity);GO:0046983(protein dimerization activity);GO:0048741(skeletal muscle fiber development);GO:0050774(negative regulation of dendrite morphogenesis);GO:0050804(modulation of chemical synaptic transmission);GO:0051091(positive regulation of DNA-binding transcription factor activity);GO:0051592(response to calcium ion);GO:0060079(excitatory postsynaptic potential);GO:0070262(peptidyl-serine dephosphorylation);GO:0070886(positive regulation of calcineurin-NFAT signaling cascade);GO:0071333(cellular response to glucose stimulus);GO:0097720(calcineurin-mediated signaling);GO:0098685(Schaffer collateral - CA1 synapse);GO:0098794(postsynapse);GO:0098978(glutamatergic synapse);GO:0099170(postsynaptic modulation of chemical synaptic transmission);GO:1903244(positive regulation of cardiac muscle hypertrophy in response to stress);GO:1903799(negative regulation of production of miRNAs involved in gene silencing by miRNA);GO:1905205(positive regulation of connective tissue replacement)","04010(MAPK signaling pathway);04020(Calcium signaling pathway);04022(cGMP-PKG signaling pathway);04114(Oocyte meiosis);04218(Cellular senescence);04310(Wnt signaling pathway);04360(Axon guidance);04370(VEGF signaling pathway);04380(Osteoclast differentiation);04625(C-type lectin receptor signaling pathway);04650(Natural killer cell mediated cytotoxicity);04658(Th1 and Th2 cell differentiation);04659(Th17 cell differentiation);04660(T cell receptor signaling pathway);04662(B cell receptor signaling pathway);04720(Long-term potentiation);04724(Glutamatergic synapse);04728(Dopaminergic synapse);04921(Oxytocin signaling pathway);04922(Glucagon signaling pathway);04924(Renin secretion);05010(Alzheimer disease);05014(Amyotrophic lateral sclerosis (ALS));05031(Amphetamine addiction);05152(Tuberculosis);05163(Human cytomegalovirus infection);05166(Human T-cell leukemia virus 1 infection);05167(Kaposi sarcoma-associated herpesvirus infection);05170(Human immunodeficiency virus 1 infection)","NA","NA","protein phosphatase 3 catalytic subunit alpha [Source:HGNC Symbol;Acc:HGNC:9314]",{"v":4.204838,"d":"4.20"},0,{"v":4.563557,"d":"4.56"},0,0,0,"inf","inf",{"v":3.08216034199726e-6,"d":"0.00"},{"v":0.000925412274584796,"d":"0.00"},"up","yes"]
[80355,0,"chr17","+",5282487,5383223,"ENST00000341923",17,2490,"ENSG00000029725","RABEP1","GO:0005096(GTPase activator activity);GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0005768(endosome);GO:0005769(early endosome);GO:0006893(Golgi to plasma membrane transport);GO:0006897(endocytosis);GO:0006915(apoptotic process);GO:0008083(growth factor activity);GO:0010469(regulation of signaling receptor activity);GO:0015031(protein transport);GO:0016192(vesicle-mediated transport);GO:0019904(protein domain specific binding);GO:0030139(endocytic vesicle);GO:0031410(cytoplasmic vesicle);GO:0031901(early endosome membrane);GO:0032991(protein-containing complex);GO:0042803(protein homodimerization activity);GO:0043231(intracellular membrane-bounded organelle);GO:0043547(positive regulation of GTPase activity);GO:0055037(recycling endosome);GO:0061025(membrane fusion);GO:1903441(protein localization to ciliary membrane)","04144(Endocytosis)","NA","NA","rabaptin, RAB GTPase binding effector protein 1 [Source:HGNC Symbol;Acc:HGNC:17677]",0,0,0,{"v":0.267482,"d":"0.27"},{"v":0.825449,"d":"0.83"},{"v":0.709548,"d":"0.71"},"-inf","-inf",{"v":3.17618870527728e-6,"d":"0.00"},{"v":0.000945827341497736,"d":"0.00"},"down","yes"]
[72223,0,"chr16","+",19716456,19857539,"ENST00000308214",8,2423,"ENSG00000174628","IQCK","NA","NA","NA","NA","IQ motif containing K [Source:HGNC Symbol;Acc:HGNC:28556]",0,0,0,{"v":0.427229,"d":"0.43"},{"v":0.773305,"d":"0.77"},{"v":0.528394,"d":"0.53"},"-inf","-inf",{"v":3.21259943620335e-6,"d":"0.00"},{"v":0.000948892174937137,"d":"0.00"},"down","yes"]
[89443,0,"chr17","+",68248043,68257154,"ENST00000392720",8,1378,"ENSG00000196704","AMZ2","GO:0005575(cellular_component);GO:0006508(proteolysis);GO:0008233(peptidase activity);GO:0008237(metallopeptidase activity);GO:0008270(zinc ion binding);GO:0016787(hydrolase activity);GO:0046872(metal ion binding)","NA","K06974","EC:3.4.-.-","archaelysin family metallopeptidase 2 [Source:HGNC Symbol;Acc:HGNC:28041]",0,0,0,{"v":22.886271,"d":"22.89"},{"v":8.157449,"d":"8.16"},0,"-inf","-inf",{"v":3.27562020786351e-6,"d":"0.00"},{"v":0.000956936611726233,"d":"0.00"},"down","yes"]
[98970,0,"chr19","+",10984152,11062282,"ENST00000450717",35,5506,"ENSG00000127616","SMARCA4","GO:0000122(negative regulation of transcription by RNA polymerase II);GO:0000166(nucleotide binding);GO:0000790(nuclear chromatin);GO:0000978(RNA polymerase II proximal promoter sequence-specific DNA binding);GO:0000980(RNA polymerase II distal enhancer sequence-specific DNA binding);GO:0001164(RNA polymerase I CORE element sequence-specific DNA binding);GO:0001188(RNA polymerase I preinitiation complex assembly);GO:0002039(p53 binding);GO:0003407(neural retina development);GO:0003713(transcription coactivator activity);GO:0003714(transcription corepressor activity);GO:0003723(RNA binding);GO:0004386(helicase activity);GO:0005515(protein binding);GO:0005524(ATP binding);GO:0005615(extracellular space);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005730(nucleolus);GO:0006325(chromatin organization);GO:0006337(nucleosome disassembly);GO:0006338(chromatin remodeling);GO:0006355(regulation of transcription, DNA-templated);GO:0006357(regulation of transcription by RNA polymerase II);GO:0007399(nervous system development);GO:0008094(DNA-dependent ATPase activity);GO:0008134(transcription factor binding);GO:0016020(membrane);GO:0016514(SWI/SNF complex);GO:0016787(hydrolase activity);GO:0016817(hydrolase activity, acting on acid anhydrides);GO:0016887(ATPase activity);GO:0030177(positive regulation of Wnt signaling pathway);GO:0030308(negative regulation of cell growth);GO:0030957(Tat protein binding);GO:0031492(nucleosomal DNA binding);GO:0032991(protein-containing complex);GO:0038111(interleukin-7-mediated signaling pathway);GO:0042393(histone binding);GO:0043044(ATP-dependent chromatin remodeling);GO:0043923(positive regulation by host of viral transcription);GO:0045892(negative regulation of transcription, DNA-templated);GO:0045893(positive regulation of transcription, DNA-templated);GO:0045944(positive regulation of transcription by RNA polymerase II);GO:0047485(protein N-terminus binding);GO:0050681(androgen receptor binding);GO:0051091(positive regulation of DNA-binding transcription factor activity);GO:0060766(negative regulation of androgen receptor signaling pathway);GO:0070182(DNA polymerase binding);GO:0070577(lysine-acetylated histone binding);GO:0071564(npBAF complex);GO:0071565(nBAF complex);GO:1901838(positive regulation of transcription of nucleolar large rRNA by RNA polymerase I);GO:1902661(positive regulation of glucose mediated signaling pathway);GO:1902895(positive regulation of pri-miRNA transcription by RNA polymerase II);GO:1904837(beta-catenin-TCF complex assembly)","04714(Thermogenesis);05225(Hepatocellular carcinoma)","NA","NA","SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 [Source:HGNC Symbol;Acc:HGNC:11100]",{"v":2.942721,"d":"2.94"},{"v":4.157964,"d":"4.16"},0,0,0,0,"inf","inf",{"v":3.29251517934982e-6,"d":"0.00"},{"v":0.000956936611726233,"d":"0.00"},"up","yes"]
[36245,0,"chr11","+",112025408,112062771,"ENST00000533297",14,2118,"ENSG00000150768","DLAT","GO:0004742(dihydrolipoyllysine-residue acetyltransferase activity);GO:0005515(protein binding);GO:0005739(mitochondrion);GO:0005759(mitochondrial matrix);GO:0005967(mitochondrial pyruvate dehydrogenase complex);GO:0005975(carbohydrate metabolic process);GO:0006006(glucose metabolic process);GO:0006086(acetyl-CoA biosynthetic process from pyruvate);GO:0006090(pyruvate metabolic process);GO:0006099(tricarboxylic acid cycle);GO:0016740(transferase activity);GO:0016746(transferase activity, transferring acyl groups);GO:0030431(sleep);GO:0034604(pyruvate dehydrogenase (NAD+) activity);GO:0042802(identical protein binding);GO:0045254(pyruvate dehydrogenase complex)","00010(Glycolysis / Gluconeogenesis);00020(Citrate cycle (TCA cycle));00620(Pyruvate metabolism)","K00627","EC:2.3.1.12","dihydrolipoamide S-acetyltransferase [Source:HGNC Symbol;Acc:HGNC:2896]",0,0,0,{"v":1.18783,"d":"1.19"},{"v":0.894022,"d":"0.89"},{"v":0.213554,"d":"0.21"},"-inf","-inf",{"v":3.34173040434376e-6,"d":"0.00"},{"v":0.000960917619019249,"d":"0.00"},"down","yes"]
[155528,0,"chr4","-",151120284,151226066,"ENST00000409252",20,4888,"ENSG00000109686","SH3D19","GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0007010(cytoskeleton organization);GO:0022604(regulation of cell morphogenesis);GO:0051044(positive regulation of membrane protein ectodomain proteolysis)","NA","NA","NA","SH3 domain containing 19 [Source:HGNC Symbol;Acc:HGNC:30418]",{"v":0.028234,"d":"0.03"},{"v":0.016924,"d":"0.02"},{"v":0.031744,"d":"0.03"},{"v":4.073773,"d":"4.07"},{"v":1.651842,"d":"1.65"},{"v":0.350005,"d":"0.35"},{"v":0.0126574736405503,"d":"0.01"},{"v":-6.30386670996603,"d":"-6.30"},{"v":3.35911196299049e-6,"d":"0.00"},{"v":0.000960917619019249,"d":"0.00"},"down","yes"]
[128072,0,"chr20","-",57648394,57711536,"ENST00000265626",4,4627,"ENSG00000124225","PMEPA1","GO:0000139(Golgi membrane);GO:0005515(protein binding);GO:0005768(endosome);GO:0005794(Golgi apparatus);GO:0005886(plasma membrane);GO:0009968(negative regulation of signal transduction);GO:0010008(endosome membrane);GO:0010991(negative regulation of SMAD protein complex assembly);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0030512(negative regulation of transforming growth factor beta receptor signaling pathway);GO:0030521(androgen receptor signaling pathway);GO:0031901(early endosome membrane);GO:0043231(intracellular membrane-bounded organelle);GO:0050699(WW domain binding);GO:0060394(negative regulation of pathway-restricted SMAD protein phosphorylation);GO:0070412(R-SMAD binding)","NA","NA","NA","prostate transmembrane protein, androgen induced 1 [Source:HGNC Symbol;Acc:HGNC:14107]",0,0,0,{"v":3.50787,"d":"3.51"},0,{"v":4.011837,"d":"4.01"},"-inf","-inf",{"v":3.40972672746635e-6,"d":"0.00"},{"v":0.00096777634381916,"d":"0.00"},"down","yes"]
[154040,0,"chr4","-",108808725,109302658,"ENST00000399132",38,7713,"ENSG00000188517","COL25A1","GO:0001540(amyloid-beta binding);GO:0005201(extracellular matrix structural constituent);GO:0005576(extracellular region);GO:0005581(collagen trimer);GO:0005615(extracellular space);GO:0005788(endoplasmic reticulum lumen);GO:0005886(plasma membrane);GO:0005887(integral component of plasma membrane);GO:0008201(heparin binding);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0030020(extracellular matrix structural constituent conferring tensile strength);GO:0030198(extracellular matrix organization);GO:0031012(extracellular matrix);GO:0060385(axonogenesis involved in innervation);GO:0062023(collagen-containing extracellular matrix)","NA","NA","NA","collagen type XXV alpha 1 chain [Source:HGNC Symbol;Acc:HGNC:18603]",{"v":0.180685,"d":"0.18"},{"v":0.190653,"d":"0.19"},{"v":0.164072,"d":"0.16"},0,0,0,"inf","inf",{"v":3.60824930297245e-6,"d":"0.00"},{"v":0.00100846730119637,"d":"0.00"},"up","yes"]
[150039,0,"chr4","+",15479223,15601546,"ENST00000634028",34,4790,"ENSG00000048342","CC2D2A","GO:0001843(neural tube closure);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005856(cytoskeleton);GO:0005929(cilium);GO:0007224(smoothened signaling pathway);GO:0007368(determination of left/right symmetry);GO:0007507(heart development);GO:0030030(cell projection organization);GO:0035082(axoneme assembly);GO:0035869(ciliary transition zone);GO:0036038(MKS complex);GO:0042995(cell projection);GO:0043010(camera-type eye development);GO:0044458(motile cilium assembly);GO:0060271(cilium assembly);GO:0097711(ciliary basal body-plasma membrane docking);GO:1904491(protein localization to ciliary transition zone);GO:1905515(non-motile cilium assembly);GO:1990403(embryonic brain development)","NA","K19352","NA","coiled-coil and C2 domain containing 2A [Source:HGNC Symbol;Acc:HGNC:29253]",{"v":3.736367,"d":"3.74"},{"v":3.910757,"d":"3.91"},0,0,0,0,"inf","inf",{"v":3.6331310170796e-6,"d":"0.00"},{"v":0.00100846730119637,"d":"0.00"},"up","yes"]
[14115,0,"chr1","+",173824673,173858546,"ENST00000649689",17,3336,"ENSG00000117593","DARS2","GO:0000049(tRNA binding);GO:0000166(nucleotide binding);GO:0003676(nucleic acid binding);GO:0004812(aminoacyl-tRNA ligase activity);GO:0004815(aspartate-tRNA ligase activity);GO:0005515(protein binding);GO:0005524(ATP binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005739(mitochondrion);GO:0005759(mitochondrial matrix);GO:0006412(translation);GO:0006418(tRNA aminoacylation for protein translation);GO:0016874(ligase activity);GO:0042803(protein homodimerization activity);GO:0043039(tRNA aminoacylation);GO:0050560(aspartate-tRNA(Asn) ligase activity);GO:0070145(mitochondrial asparaginyl-tRNA aminoacylation)","00970(Aminoacyl-tRNA biosynthesis)","K01876","EC:6.1.1.12","aspartyl-tRNA synthetase 2, mitochondrial [Source:HGNC Symbol;Acc:HGNC:25538]",{"v":3.427562,"d":"3.43"},{"v":1.311781,"d":"1.31"},{"v":2.446662,"d":"2.45"},{"v":0.001496,"d":"0.00"},{"v":0.008698,"d":"0.01"},{"v":0.058453,"d":"0.06"},{"v":104.680539572013,"d":"104.68"},{"v":6.70984945561131,"d":"6.71"},{"v":3.63636709212015e-6,"d":"0.00"},{"v":0.00100846730119637,"d":"0.00"},"up","yes"]
[162325,0,"chr5","-",128441998,128538223,"ENST00000502468",8,1947,"ENSG00000138829","FBN2","GO:0001527(microfibril);GO:0005201(extracellular matrix structural constituent);GO:0005509(calcium ion binding);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0030023(extracellular matrix constituent conferring elasticity);GO:0030198(extracellular matrix organization);GO:0030326(embryonic limb morphogenesis);GO:0030501(positive regulation of bone mineralization);GO:0031012(extracellular matrix);GO:0035108(limb morphogenesis);GO:0035583(sequestering of TGFbeta in extracellular matrix);GO:0043010(camera-type eye development);GO:0045669(positive regulation of osteoblast differentiation);GO:0048048(embryonic eye morphogenesis);GO:0060346(bone trabecula formation);GO:0062023(collagen-containing extracellular matrix)","NA","NA","NA","fibrillin 2 [Source:HGNC Symbol;Acc:HGNC:3604]",0,0,0,{"v":0.004442,"d":"0.00"},{"v":4.254364,"d":"4.25"},{"v":5.51238,"d":"5.51"},"-inf","-inf",{"v":3.69034763150825e-6,"d":"0.00"},{"v":0.00101568431403557,"d":"0.00"},"down","yes"]
[21732,0,"chr10","-",70298973,70382589,"ENST00000373224",5,3095,"ENSG00000172731","LRRC20","GO:0005515(protein binding)","NA","NA","NA","leucine rich repeat containing 20 [Source:HGNC Symbol;Acc:HGNC:23421]",{"v":0.001395,"d":"0.00"},0,0,{"v":1.39965,"d":"1.40"},{"v":0.026149,"d":"0.03"},{"v":2.867965,"d":"2.87"},{"v":0.000324889770373966,"d":"0.00"},{"v":-11.5877620605145,"d":"-11.59"},{"v":3.83306758159313e-6,"d":"0.00"},{"v":0.00104703267097202,"d":"0.00"},"down","yes"]
[9487,0,"chr1","+",111449485,111461312,"ENST00000468818",6,859,"ENSG00000116459","ATP5PB","GO:0000276(mitochondrial proton-transporting ATP synthase complex, coupling factor F(o));GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005739(mitochondrion);GO:0005743(mitochondrial inner membrane);GO:0005753(mitochondrial proton-transporting ATP synthase complex);GO:0005759(mitochondrial matrix);GO:0006754(ATP biosynthetic process);GO:0006811(ion transport);GO:0015078(proton transmembrane transporter activity);GO:0015986(ATP synthesis coupled proton transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016887(ATPase activity);GO:0021762(substantia nigra development);GO:0022857(transmembrane transporter activity);GO:0042407(cristae formation);GO:0042776(mitochondrial ATP synthesis coupled proton transport);GO:0045263(proton-transporting ATP synthase complex, coupling factor F(o));GO:0046933(proton-transporting ATP synthase activity, rotational mechanism);GO:0099132(ATP hydrolysis coupled cation transmembrane transport)","00190(Oxidative phosphorylation);04714(Thermogenesis);05010(Alzheimer disease);05012(Parkinson disease);05016(Huntington disease)","NA","NA","ATP synthase peripheral stalk-membrane subunit b [Source:HGNC Symbol;Acc:HGNC:840]",0,0,0,{"v":26.128887,"d":"26.13"},{"v":15.520008,"d":"15.52"},0,"-inf","-inf",{"v":3.92290242576958e-6,"d":"0.00"},{"v":0.00106357496364335,"d":"0.00"},"down","yes"]
[131579,0,"chr22","+",17638741,17728699,"ENST00000498133",6,2662,"ENSG00000099968","BCL2L13","GO:0005515(protein binding);GO:0005634(nucleus);GO:0005739(mitochondrion);GO:0006915(apoptotic process);GO:0006919(activation of cysteine-type endopeptidase activity involved in apoptotic process);GO:0008656(cysteine-type endopeptidase activator activity involved in apoptotic process);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0031966(mitochondrial membrane);GO:0042981(regulation of apoptotic process)","04137(Mitophagy - animal);05134(Legionellosis)","K15485","NA","BCL2 like 13 [Source:HGNC Symbol;Acc:HGNC:17164]",0,0,0,{"v":6.411563,"d":"6.41"},{"v":6.44547,"d":"6.45"},0,"-inf","-inf",{"v":4.02349424887877e-6,"d":"0.00"},{"v":0.00107650882430503,"d":"0.00"},"down","yes"]
[60571,0,"chr14","+",102139924,102210470,"ENST00000556511",2,2117,"ENSG00000140153","WDR20","GO:0005515(protein binding);GO:0005654(nucleoplasm);GO:0016579(protein deubiquitination)","NA","NA","NA","WD repeat domain 20 [Source:HGNC Symbol;Acc:HGNC:19667]",{"v":0.241358,"d":"0.24"},{"v":1.482058,"d":"1.48"},{"v":0.60072,"d":"0.60"},0,0,0,"inf","inf",{"v":4.02987063323657e-6,"d":"0.00"},{"v":0.00107650882430503,"d":"0.00"},"up","yes"]
[160084,0,"chr5","-",75371121,75506004,"ENST00000380494",16,4654,"ENSG00000113163","COL4A3BP","GO:0000902(cell morphogenesis);GO:0001701(in utero embryonic development);GO:0003007(heart morphogenesis);GO:0005515(protein binding);GO:0005581(collagen trimer);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0005739(mitochondrion);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005794(Golgi apparatus);GO:0005829(cytosol);GO:0006672(ceramide metabolic process);GO:0006869(lipid transport);GO:0006936(muscle contraction);GO:0006955(immune response);GO:0007029(endoplasmic reticulum organization);GO:0007165(signal transduction);GO:0008283(cell population proliferation);GO:0008289(lipid binding);GO:0016020(membrane);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0030148(sphingolipid biosynthetic process);GO:0034976(response to endoplasmic reticulum stress);GO:0035621(ER to Golgi ceramide transport);GO:0035627(ceramide transport);GO:0048471(perinuclear region of cytoplasm);GO:0055088(lipid homeostasis);GO:0070273(phosphatidylinositol-4-phosphate binding);GO:0070584(mitochondrion morphogenesis);GO:0097001(ceramide binding);GO:0120009(intermembrane lipid transfer);GO:0120012(intermembrane sphingolipid transfer);GO:0120017(intermembrane ceramide transfer activity);GO:1902387(ceramide 1-phosphate binding);GO:1902388(ceramide 1-phosphate transporter activity);GO:1902389(ceramide 1-phosphate transport)","NA","K08283","NA","collagen type IV alpha 3 binding protein [Source:HGNC Symbol;Acc:HGNC:2205]",0,{"v":3.769539,"d":"3.77"},{"v":3.655648,"d":"3.66"},0,0,0,"inf","inf",{"v":4.31985921828334e-6,"d":"0.00"},{"v":0.00114555098832287,"d":"0.00"},"up","yes"]
[110562,0,"chr2","-",26190671,26244610,"ENST00000643057",19,2977,"ENSG00000084754","HADHA","GO:0000062(fatty-acyl-CoA binding);GO:0003824(catalytic activity);GO:0003857(3-hydroxyacyl-CoA dehydrogenase activity);GO:0003985(acetyl-CoA C-acetyltransferase activity);GO:0003988(acetyl-CoA C-acyltransferase activity);GO:0004300(enoyl-CoA hydratase activity);GO:0005515(protein binding);GO:0005739(mitochondrion);GO:0005743(mitochondrial inner membrane);GO:0006629(lipid metabolic process);GO:0006631(fatty acid metabolic process);GO:0006635(fatty acid beta-oxidation);GO:0008152(metabolic process);GO:0016491(oxidoreductase activity);GO:0016507(mitochondrial fatty acid beta-oxidation multienzyme complex);GO:0016508(long-chain-enoyl-CoA hydratase activity);GO:0016509(long-chain-3-hydroxyacyl-CoA dehydrogenase activity);GO:0016829(lyase activity);GO:0032868(response to insulin);GO:0035965(cardiolipin acyl-chain remodeling);GO:0042493(response to drug);GO:0042645(mitochondrial nucleoid);GO:0044877(protein-containing complex binding);GO:0051287(NAD binding);GO:0055114(oxidation-reduction process)","00062(Fatty acid elongation);00071(Fatty acid degradation);00280(Valine, leucine and isoleucine degradation);00310(Lysine degradation);00380(Tryptophan metabolism);00410(beta-Alanine metabolism);00640(Propanoate metabolism);00650(Butanoate metabolism)","K07515","1.1.1.211;EC:4.2.1.17","hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha [Source:HGNC Symbol;Acc:HGNC:4801]",0,{"v":0.001605,"d":"0.00"},0,{"v":3.535884,"d":"3.54"},{"v":5.98412,"d":"5.98"},{"v":0.00296,"d":"0.00"},{"v":0.000168539962977913,"d":"0.00"},{"v":-12.5346216661588,"d":"-12.53"},{"v":4.41232991494161e-6,"d":"0.00"},{"v":0.00116159381021615,"d":"0.00"},"down","yes"]
[197390,0,"chr9","-",92456205,92482562,"ENST00000651777",8,2526,"ENSG00000106819","ASPN","GO:0005509(calcium ion binding);GO:0005515(protein binding);GO:0005518(collagen binding);GO:0005576(extracellular region);GO:0030021(extracellular matrix structural constituent conferring compression resistance);GO:0030282(bone mineralization);GO:0030512(negative regulation of transforming growth factor beta receptor signaling pathway);GO:0031012(extracellular matrix);GO:0031214(biomineral tissue development);GO:0062023(collagen-containing extracellular matrix);GO:0070171(negative regulation of tooth mineralization)","NA","K08120","NA","asporin [Source:HGNC Symbol;Acc:HGNC:14872]",{"v":0.210795,"d":"0.21"},{"v":0.136383,"d":"0.14"},{"v":0.120215,"d":"0.12"},{"v":17.840069,"d":"17.84"},{"v":21.107687,"d":"21.11"},{"v":0.189079,"d":"0.19"},{"v":0.0119425344435747,"d":"0.01"},{"v":-6.38774715206936,"d":"-6.39"},{"v":4.51311160594198e-6,"d":"0.00"},{"v":0.00117957801902066,"d":"0.00"},"down","yes"]
[164890,0,"chr5","-",157786287,157859133,"ENST00000530742",12,3344,"ENSG00000113282","CLINT1","GO:0005515(protein binding);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0005794(Golgi apparatus);GO:0005829(cytosol);GO:0006897(endocytosis);GO:0008289(lipid binding);GO:0016020(membrane);GO:0016192(vesicle-mediated transport);GO:0030136(clathrin-coated vesicle);GO:0030276(clathrin binding);GO:0031410(cytoplasmic vesicle);GO:0043231(intracellular membrane-bounded organelle);GO:0045296(cadherin binding);GO:0048268(clathrin coat assembly);GO:0048471(perinuclear region of cytoplasm)","NA","NA","NA","clathrin interactor 1 [Source:HGNC Symbol;Acc:HGNC:23186]",{"v":4.854638,"d":"4.85"},0,{"v":4.940602,"d":"4.94"},0,0,0,"inf","inf",{"v":4.74891944048098e-6,"d":"0.00"},{"v":0.00123234459480481,"d":"0.00"},"up","yes"]
[102632,0,"chr19","+",35629131,35637641,"ENST00000589871",9,1487,"ENSG00000126254","RBM42","GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0048025(negative regulation of mRNA splicing, via spliceosome);GO:1990904(ribonucleoprotein complex)","NA","NA","NA","RNA binding motif protein 42 [Source:HGNC Symbol;Acc:HGNC:28117]",0,{"v":11.718085,"d":"11.72"},{"v":10.339564,"d":"10.34"},0,0,0,"inf","inf",{"v":4.83271306498722e-6,"d":"0.00"},{"v":0.00124519479185096,"d":"0.00"},"up","yes"]
[170639,0,"chr6","+",42782027,42868560,"ENST00000314073",13,6530,"ENSG00000112624","BICRAL","GO:0016514(SWI/SNF complex)","NA","NA","NA","BRD4 interacting chromatin remodeling complex associated protein like [Source:HGNC Symbol;Acc:HGNC:21111]",0,0,0,{"v":2.420562,"d":"2.42"},{"v":2.417758,"d":"2.42"},0,"-inf","-inf",{"v":4.92540417243629e-6,"d":"0.00"},{"v":0.00126014037735641,"d":"0.00"},"down","yes"]
[188728,0,"chr8","-",41929479,42051994,"ENST00000406337",18,9254,"ENSG00000083168","KAT6A","GO:0000123(histone acetyltransferase complex);GO:0000786(nucleosome);GO:0000790(nuclear chromatin);GO:0003677(DNA binding);GO:0003713(transcription coactivator activity);GO:0004402(histone acetyltransferase activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005730(nucleolus);GO:0005829(cytosol);GO:0006323(DNA packaging);GO:0006325(chromatin organization);GO:0006334(nucleosome assembly);GO:0006355(regulation of transcription, DNA-templated);GO:0006473(protein acetylation);GO:0008134(transcription factor binding);GO:0008270(zinc ion binding);GO:0010485(H4 histone acetyltransferase activity);GO:0016407(acetyltransferase activity);GO:0016573(histone acetylation);GO:0016605(PML body);GO:0016607(nuclear speck);GO:0016740(transferase activity);GO:0016746(transferase activity, transferring acyl groups);GO:0030099(myeloid cell differentiation);GO:0042393(histone binding);GO:0043966(histone H3 acetylation);GO:0043967(histone H4 acetylation);GO:0045892(negative regulation of transcription, DNA-templated);GO:0045893(positive regulation of transcription, DNA-templated);GO:0045944(positive regulation of transcription by RNA polymerase II);GO:0046872(metal ion binding);GO:0048513(animal organ development);GO:0070776(MOZ/MORF histone acetyltransferase complex);GO:0090398(cellular senescence);GO:1901796(regulation of signal transduction by p53 class mediator);GO:1903508(positive regulation of nucleic acid-templated transcription)","04550(Signaling pathways regulating pluripotency of stem cells)","NA","NA","lysine acetyltransferase 6A [Source:HGNC Symbol;Acc:HGNC:13013]",0,0,0,{"v":8.9e-5,"d":"0.00"},{"v":0.919833,"d":"0.92"},{"v":0.792495,"d":"0.79"},"-inf","-inf",{"v":5.00311406044449e-6,"d":"0.00"},{"v":0.00126652064354644,"d":"0.00"},"down","yes"]
[119443,0,"chr2","-",174799524,174847225,"ENST00000651717",6,1606,"ENSG00000128656","CHN1","GO:0005070(SH3/SH2 adaptor activity);GO:0005096(GTPase activator activity);GO:0005515(protein binding);GO:0005829(cytosol);GO:0007165(signal transduction);GO:0007399(nervous system development);GO:0008045(motor neuron axon guidance);GO:0009967(positive regulation of signal transduction);GO:0035556(intracellular signal transduction);GO:0043087(regulation of GTPase activity);GO:0043547(positive regulation of GTPase activity);GO:0046872(metal ion binding);GO:0046875(ephrin receptor binding);GO:0048013(ephrin receptor signaling pathway);GO:0050770(regulation of axonogenesis);GO:0051056(regulation of small GTPase mediated signal transduction)","NA","NA","NA","chimerin 1 [Source:HGNC Symbol;Acc:HGNC:1943]",0,0,0,{"v":1.518189,"d":"1.52"},{"v":36.580116,"d":"36.58"},0,"-inf","-inf",{"v":5.0200653088546e-6,"d":"0.00"},{"v":0.00126652064354644,"d":"0.00"},"down","yes"]
[6186,0,"chr1","-",51789196,51878040,"ENST00000539524",33,3417,"ENSG00000078618","NRDC","GO:0003824(catalytic activity);GO:0004222(metalloendopeptidase activity);GO:0005515(protein binding);GO:0005739(mitochondrion);GO:0005829(cytosol);GO:0006508(proteolysis);GO:0007528(neuromuscular junction development);GO:0008233(peptidase activity);GO:0008237(metallopeptidase activity);GO:0008283(cell population proliferation);GO:0009986(cell surface);GO:0016477(cell migration);GO:0016787(hydrolase activity);GO:0046872(metal ion binding);GO:0048408(epidermal growth factor binding);GO:0051044(positive regulation of membrane protein ectodomain proteolysis);GO:0052548(regulation of endopeptidase activity);GO:0120163(negative regulation of cold-induced thermogenesis)","NA","K01411","EC:3.4.24.61","nardilysin convertase [Source:HGNC Symbol;Acc:HGNC:7995]",{"v":0.003549,"d":"0.00"},{"v":0.965356,"d":"0.97"},{"v":2.860137,"d":"2.86"},0,0,0,"inf","inf",{"v":5.05905039612847e-6,"d":"0.00"},{"v":0.00126755379925067,"d":"0.00"},"up","yes"]
[149306,0,"chr4","+",2625462,2731889,"ENST00000502458",20,4083,"ENSG00000125386","FAM193A","NA","NA","NA","NA","family with sequence similarity 193 member A [Source:HGNC Symbol;Acc:HGNC:16822]",0,0,0,{"v":0.410275,"d":"0.41"},{"v":0.393922,"d":"0.39"},{"v":0.179643,"d":"0.18"},"-inf","-inf",{"v":5.15535149944028e-6,"d":"0.00"},{"v":0.00128283506831963,"d":"0.00"},"down","yes"]
[161961,0,"chr5","+",119477479,119541994,"ENST00000646646",18,1791,"ENSG00000133835","HSD17B4","GO:0000038(very long-chain fatty acid metabolic process);GO:0001649(osteoblast differentiation);GO:0003857(3-hydroxyacyl-CoA dehydrogenase activity);GO:0005102(signaling receptor binding);GO:0005777(peroxisome);GO:0005778(peroxisomal membrane);GO:0005782(peroxisomal matrix);GO:0005829(cytosol);GO:0006625(protein targeting to peroxisome);GO:0006629(lipid metabolic process);GO:0006631(fatty acid metabolic process);GO:0006635(fatty acid beta-oxidation);GO:0006699(bile acid biosynthetic process);GO:0008209(androgen metabolic process);GO:0008210(estrogen metabolic process);GO:0016020(membrane);GO:0016491(oxidoreductase activity);GO:0016508(long-chain-enoyl-CoA hydratase activity);GO:0016829(lyase activity);GO:0016853(isomerase activity);GO:0033540(fatty acid beta-oxidation using acyl-CoA oxidase);GO:0033989(3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA hydratase activity);GO:0036109(alpha-linolenic acid metabolic process);GO:0036111(very long-chain fatty-acyl-CoA metabolic process);GO:0036112(medium-chain fatty-acyl-CoA metabolic process);GO:0042803(protein homodimerization activity);GO:0044594(17-beta-hydroxysteroid dehydrogenase (NAD+) activity);GO:0055114(oxidation-reduction process);GO:0060009(Sertoli cell development)","00120(Primary bile acid biosynthesis);01040(Biosynthesis of unsaturated fatty acids);04146(Peroxisome)","K12405","4.2.1.107;4.2.1.119;EC:1.1.1.-","hydroxysteroid 17-beta dehydrogenase 4 [Source:HGNC Symbol;Acc:HGNC:5213]",{"v":8.371437,"d":"8.37"},{"v":8.963121,"d":"8.96"},0,0,0,0,"inf","inf",{"v":5.19631948004635e-6,"d":"0.00"},{"v":0.00128423324292574,"d":"0.00"},"up","yes"]
[150049,0,"chr4","-",15605006,15644649,"ENST00000513163",9,2554,"ENSG00000118564","FBXL5","GO:0000151(ubiquitin ligase complex);GO:0000209(protein polyubiquitination);GO:0004842(ubiquitin-protein transferase activity);GO:0005506(iron ion binding);GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0006511(ubiquitin-dependent protein catabolic process);GO:0006879(cellular iron ion homeostasis);GO:0016567(protein ubiquitination);GO:0019005(SCF ubiquitin ligase complex);GO:0031146(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process);GO:0043687(post-translational protein modification);GO:0046872(metal ion binding);GO:0048471(perinuclear region of cytoplasm);GO:0055072(iron ion homeostasis);GO:1903364(positive regulation of cellular protein catabolic process)","NA","K10271","NA","F-box and leucine rich repeat protein 5 [Source:HGNC Symbol;Acc:HGNC:13602]",{"v":8.768845,"d":"8.77"},{"v":4.148321,"d":"4.15"},0,0,0,0,"inf","inf",{"v":5.25277418178305e-6,"d":"0.00"},{"v":0.00128941409475796,"d":"0.00"},"up","yes"]
[152631,0,"chr4","+",82451070,82461090,"ENST00000610545",4,1543,"ENSG00000145293","ENOPH1","GO:0000287(magnesium ion binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0008652(cellular amino acid biosynthetic process);GO:0009086(methionine biosynthetic process);GO:0016311(dephosphorylation);GO:0016787(hydrolase activity);GO:0019284(L-methionine salvage from S-adenosylmethionine);GO:0019509(L-methionine salvage from methylthioadenosine);GO:0043715(2,3-diketo-5-methylthiopentyl-1-phosphate enolase activity);GO:0043716(2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate phosphatase activity);GO:0043874(acireductone synthase activity);GO:0046872(metal ion binding)","00270(Cysteine and methionine metabolism)","K09880","EC:3.1.3.77","enolase-phosphatase 1 [Source:HGNC Symbol;Acc:HGNC:24599]",0,{"v":6.5e-5,"d":"0.00"},0,{"v":0.000148,"d":"0.00"},{"v":9.370383,"d":"9.37"},{"v":7.712422,"d":"7.71"},{"v":3.80496276024409e-6,"d":"0.00"},{"v":-18.0036862354046,"d":"-18.00"},{"v":5.35657647960211e-6,"d":"0.00"},{"v":0.00130148054663942,"d":"0.00"},"down","yes"]
[15264,0,"chr1","+",201648249,201826969,"ENST00000367296",30,13091,"ENSG00000134369","NAV1","GO:0001578(microtubule bundle formation);GO:0001764(neuron migration);GO:0005737(cytoplasm);GO:0005856(cytoskeleton);GO:0005874(microtubule);GO:0007275(multicellular organism development);GO:0007399(nervous system development);GO:0015630(microtubule cytoskeleton);GO:0022008(neurogenesis);GO:0030154(cell differentiation);GO:0043194(axon initial segment)","NA","K16776","NA","neuron navigator 1 [Source:HGNC Symbol;Acc:HGNC:15989]",{"v":1.65656,"d":"1.66"},{"v":1.562002,"d":"1.56"},{"v":1.508752,"d":"1.51"},{"v":0.032552,"d":"0.03"},{"v":0.012929,"d":"0.01"},{"v":0.100454,"d":"0.10"},{"v":32.3932846815363,"d":"32.39"},{"v":5.01762285982498,"d":"5.02"},{"v":5.37357781436591e-6,"d":"0.00"},{"v":0.00130148054663942,"d":"0.00"},"up","yes"]
[180457,0,"chr7","+",77798901,77957225,"ENST00000275575",17,4541,"ENSG00000006576","PHTF2","GO:0003677(DNA binding);GO:0005634(nucleus);GO:0005783(endoplasmic reticulum)","NA","NA","NA","putative homeodomain transcription factor 2 [Source:HGNC Symbol;Acc:HGNC:13411]",0,0,0,{"v":3.558537,"d":"3.56"},0,{"v":2.504687,"d":"2.50"},"-inf","-inf",{"v":5.44784460069267e-6,"d":"0.00"},{"v":0.00131034707757101,"d":"0.00"},"down","yes"]
[203081,0,"chrX","-",48973723,49002234,"ENST00000593475",25,2908,"ENSG00000068400","GRIPAP1","GO:0003674(molecular_function);GO:0005515(protein binding);GO:0005654(nucleoplasm);GO:0005768(endosome);GO:0005829(cytosol);GO:0008150(biological_process);GO:0015031(protein transport);GO:0016020(membrane);GO:0030054(cell junction);GO:0030424(axon);GO:0030425(dendrite);GO:0031901(early endosome membrane);GO:0042995(cell projection);GO:0043231(intracellular membrane-bounded organelle);GO:0045202(synapse);GO:0055038(recycling endosome membrane);GO:0072562(blood microparticle);GO:0098837(postsynaptic recycling endosome);GO:0098887(neurotransmitter receptor transport, endosome to postsynaptic membrane);GO:0098978(glutamatergic synapse);GO:0098998(extrinsic component of postsynaptic early endosome membrane);GO:0099152(regulation of neurotransmitter receptor transport, endosome to postsynaptic membrane);GO:0099158(regulation of recycling endosome localization within postsynapse);GO:1905244(regulation of modification of synaptic structure)","NA","NA","NA","GRIP1 associated protein 1 [Source:HGNC Symbol;Acc:HGNC:18706]",{"v":4.78836,"d":"4.79"},{"v":5.51164,"d":"5.51"},0,0,0,0,"inf","inf",{"v":5.48232193203397e-6,"d":"0.00"},{"v":0.00131034707757101,"d":"0.00"},"up","yes"]
[74158,0,"chr16","-",31489471,31508391,"ENST00000570164",13,2783,"ENSG00000140688","C16orf58","GO:0016020(membrane);GO:0016021(integral component of membrane)","NA","NA","NA","chromosome 16 open reading frame 58 [Source:HGNC Symbol;Acc:HGNC:25848]",{"v":5.337316,"d":"5.34"},0,{"v":5.342726,"d":"5.34"},0,0,0,"inf","inf",{"v":5.52815703800756e-6,"d":"0.00"},{"v":0.0013126663084367,"d":"0.00"},"up","yes"]
[27968,0,"chr11","+",17295322,17331523,"ENST00000458064",11,1279,"ENSG00000070081","NUCB2","GO:0003677(DNA binding);GO:0005509(calcium ion binding);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0005615(extracellular space);GO:0005634(nucleus);GO:0005635(nuclear envelope);GO:0005640(nuclear outer membrane);GO:0005737(cytoplasm);GO:0005783(endoplasmic reticulum);GO:0005793(endoplasmic reticulum-Golgi intermediate compartment);GO:0005794(Golgi apparatus);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0016020(membrane);GO:0032099(negative regulation of appetite);GO:0046872(metal ion binding);GO:0070062(extracellular exosome)","NA","K20371","NA","nucleobindin 2 [Source:HGNC Symbol;Acc:HGNC:8044]",0,0,0,{"v":1.121409,"d":"1.12"},{"v":0.681467,"d":"0.68"},{"v":1.220251,"d":"1.22"},"-inf","-inf",{"v":5.57737392274642e-6,"d":"0.00"},{"v":0.00131575321177518,"d":"0.00"},"down","yes"]
[148267,0,"chr3","-",195570591,195584033,"ENST00000463719",4,1210,"ENSG00000189058","APOD","GO:0000302(response to reactive oxygen species);GO:0001525(angiogenesis);GO:0005319(lipid transporter activity);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0005615(extracellular space);GO:0005737(cytoplasm);GO:0005783(endoplasmic reticulum);GO:0006006(glucose metabolic process);GO:0006629(lipid metabolic process);GO:0006869(lipid transport);GO:0007420(brain development);GO:0007568(aging);GO:0008289(lipid binding);GO:0010642(negative regulation of platelet-derived growth factor receptor signaling pathway);GO:0014012(peripheral nervous system axon regeneration);GO:0015485(cholesterol binding);GO:0022626(cytosolic ribosome);GO:0030425(dendrite);GO:0042246(tissue regeneration);GO:0042308(negative regulation of protein import into nucleus);GO:0042493(response to drug);GO:0043025(neuronal cell body);GO:0048471(perinuclear region of cytoplasm);GO:0048662(negative regulation of smooth muscle cell proliferation);GO:0048678(response to axon injury);GO:0051895(negative regulation of focal adhesion assembly);GO:0060588(negative regulation of lipoprotein lipid oxidation);GO:0070062(extracellular exosome);GO:0071638(negative regulation of monocyte chemotactic protein-1 production);GO:1900016(negative regulation of cytokine production involved in inflammatory response);GO:2000098(negative regulation of smooth muscle cell-matrix adhesion);GO:2000405(negative regulation of T cell migration)","NA","NA","NA","apolipoprotein D [Source:HGNC Symbol;Acc:HGNC:612]",{"v":0.634633,"d":"0.63"},{"v":0.754065,"d":"0.75"},{"v":0.606774,"d":"0.61"},{"v":18.234257,"d":"18.23"},{"v":16.109541,"d":"16.11"},{"v":10.307256,"d":"10.31"},{"v":0.044690367219551,"d":"0.04"},{"v":-4.48389229040657,"d":"-4.48"},{"v":5.71017642519481e-6,"d":"0.00"},{"v":0.00133664849460426,"d":"0.00"},"down","yes"]
[173310,0,"chr6","-",113940718,113970724,"ENST00000519108",14,2000,"ENSG00000196591","HDAC2","GO:0000118(histone deacetylase complex);GO:0000122(negative regulation of transcription by RNA polymerase II);GO:0000785(chromatin);GO:0000790(nuclear chromatin);GO:0000978(RNA polymerase II proximal promoter sequence-specific DNA binding);GO:0000980(RNA polymerase II distal enhancer sequence-specific DNA binding);GO:0001103(RNA polymerase II repressing transcription factor binding);GO:0001975(response to amphetamine);GO:0003300(cardiac muscle hypertrophy);GO:0003682(chromatin binding);GO:0003723(RNA binding);GO:0004407(histone deacetylase activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0006325(chromatin organization);GO:0006338(chromatin remodeling);GO:0006344(maintenance of chromatin silencing);GO:0007596(blood coagulation);GO:0008134(transcription factor binding);GO:0008284(positive regulation of cell population proliferation);GO:0009913(epidermal cell differentiation);GO:0010718(positive regulation of epithelial to mesenchymal transition);GO:0010870(positive regulation of receptor biosynthetic process);GO:0010977(negative regulation of neuron projection development);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016358(dendrite development);GO:0016575(histone deacetylation);GO:0016580(Sin3 complex);GO:0016581(NuRD complex);GO:0016787(hydrolase activity);GO:0019213(deacetylase activity);GO:0019899(enzyme binding);GO:0031000(response to caffeine);GO:0031072(heat shock protein binding);GO:0031492(nucleosomal DNA binding);GO:0032041(NAD-dependent histone deacetylase activity (H3-K14 specific));GO:0032496(response to lipopolysaccharide);GO:0032732(positive regulation of interleukin-1 production);GO:0032760(positive regulation of tumor necrosis factor production);GO:0032922(circadian regulation of gene expression);GO:0032967(positive regulation of collagen biosynthetic process);GO:0032991(protein-containing complex);GO:0033558(protein deacetylase activity);GO:0034605(cellular response to heat);GO:0035094(response to nicotine);GO:0035098(ESC/E(Z) complex);GO:0042220(response to cocaine);GO:0042475(odontogenesis of dentin-containing tooth);GO:0042493(response to drug);GO:0042531(positive regulation of tyrosine phosphorylation of STAT protein);GO:0042733(embryonic digit morphogenesis);GO:0042826(histone deacetylase binding);GO:0043044(ATP-dependent chromatin remodeling);GO:0043066(negative regulation of apoptotic process);GO:0043392(negative regulation of DNA binding);GO:0043433(negative regulation of DNA-binding transcription factor activity);GO:0043565(sequence-specific DNA binding);GO:0045347(negative regulation of MHC class II biosynthetic process);GO:0045862(positive regulation of proteolysis);GO:0045892(negative regulation of transcription, DNA-templated);GO:0045893(positive regulation of transcription, DNA-templated);GO:0045944(positive regulation of transcription by RNA polymerase II);GO:0048149(behavioral response to ethanol);GO:0048511(rhythmic process);GO:0048714(positive regulation of oligodendrocyte differentiation);GO:0051059(NF-kappaB binding);GO:0055093(response to hyperoxia);GO:0060789(hair follicle placode formation);GO:0061000(negative regulation of dendritic spine development);GO:0061029(eyelid development in camera-type eye);GO:0061198(fungiform papilla formation);GO:0070301(cellular response to hydrogen peroxide);GO:0070822(Sin3-type complex);GO:0070932(histone H3 deacetylation);GO:0070933(histone H4 deacetylation);GO:0071300(cellular response to retinoic acid);GO:0071560(cellular response to transforming growth factor beta stimulus);GO:1901796(regulation of signal transduction by p53 class mediator);GO:1902437(positive regulation of male mating behavior);GO:1903351(cellular response to dopamine);GO:1990841(promoter-specific chromatin binding);GO:2000757(negative regulation of peptidyl-lysine acetylation)","04110(Cell cycle);04213(Longevity regulating pathway - multiple species);04330(Notch signaling pathway);04919(Thyroid hormone signaling pathway);05016(Huntington disease);05034(Alcoholism);05165(Human papillomavirus infection);05169(Epstein-Barr virus infection);05200(Pathways in cancer);05202(Transcriptional misregulation in cancer);05203(Viral carcinogenesis);05220(Chronic myeloid leukemia)","K06067","EC:3.5.1.98","histone deacetylase 2 [Source:HGNC Symbol;Acc:HGNC:4853]",{"v":0.000704,"d":"0.00"},{"v":10.642818,"d":"10.64"},{"v":4.921704,"d":"4.92"},{"v":0.000736,"d":"0.00"},0,{"v":0.000675,"d":"0.00"},{"v":11031.3437278526,"d":"11031.34"},{"v":13.4293209158491,"d":"13.43"},{"v":5.73953110812727e-6,"d":"0.00"},{"v":0.00133664849460426,"d":"0.00"},"up","yes"]
[32357,0,"chr11","-",65538991,65558038,"ENST00000528516",27,3935,"ENSG00000168056","LTBP3","GO:0005509(calcium ion binding);GO:0005576(extracellular region);GO:0019838(growth factor binding);GO:0036363(transforming growth factor beta activation);GO:0050431(transforming growth factor beta binding);GO:0062023(collagen-containing extracellular matrix);GO:0070062(extracellular exosome);GO:1902462(positive regulation of mesenchymal stem cell proliferation);GO:2000741(positive regulation of mesenchymal stem cell differentiation)","NA","K08023","NA","latent transforming growth factor beta binding protein 3 [Source:HGNC Symbol;Acc:HGNC:6716]",{"v":2.727489,"d":"2.73"},{"v":4.874625,"d":"4.87"},0,0,0,0,"inf","inf",{"v":5.89081641752042e-6,"d":"0.00"},{"v":0.00136314242323896,"d":"0.00"},"up","yes"]
[73606,0,"chr16","+",30053127,30070413,"ENST00000566897",12,2448,"ENSG00000285043","AC093512","GO:0003824(catalytic activity);GO:0004332(fructose-bisphosphate aldolase activity);GO:0005829(cytosol);GO:0006096(glycolytic process);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016829(lyase activity)","NA","NA","NA","Homo sapiens uncharaterized LOC112694756 (LOC112694756), transcript variant 1, mRNA. [Source:RefSeq mRNA;Acc:NM_001365304]",0,0,0,0,{"v":25.143198,"d":"25.14"},{"v":0.74453,"d":"0.74"},"-inf","-inf",{"v":6.00150582372866e-6,"d":"0.00"},{"v":0.00137996649731685,"d":"0.00"},"down","yes"]
[144556,0,"chr3","+",134486254,134561895,"ENST00000606977",15,2800,"ENSG00000182923","CEP63","GO:0000077(DNA damage checkpoint);GO:0000086(G2/M transition of mitotic cell cycle);GO:0000922(spindle pole);GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0005813(centrosome);GO:0005814(centriole);GO:0005815(microtubule organizing center);GO:0005829(cytosol);GO:0005856(cytoskeleton);GO:0006974(cellular response to DNA damage stimulus);GO:0007049(cell cycle);GO:0007099(centriole replication);GO:0010389(regulation of G2/M transition of mitotic cell cycle);GO:0042770(signal transduction in response to DNA damage);GO:0051225(spindle assembly);GO:0051301(cell division);GO:0097711(ciliary basal body-plasma membrane docking);GO:0098535(de novo centriole assembly involved in multi-ciliated epithelial cell differentiation)","NA","K16763","NA","centrosomal protein 63 [Source:HGNC Symbol;Acc:HGNC:25815]",{"v":0.185481,"d":"0.19"},{"v":0.54507,"d":"0.55"},{"v":0.78299,"d":"0.78"},0,0,0,"inf","inf",{"v":6.08156291692899e-6,"d":"0.00"},{"v":0.00138957975328321,"d":"0.00"},"up","yes"]
[12321,0,"chr1","+",156082573,156134487,"ENST00000502751",4,570,"ENSG00000160789","LMNA","GO:0005198(structural molecule activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005635(nuclear envelope);GO:0005638(lamin filament);GO:0005652(nuclear lamina);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0005882(intermediate filament);GO:0006606(protein import into nucleus);GO:0006997(nucleus organization);GO:0006998(nuclear envelope organization);GO:0007084(mitotic nuclear envelope reassembly);GO:0008285(negative regulation of cell population proliferation);GO:0010628(positive regulation of gene expression);GO:0016607(nuclear speck);GO:0030334(regulation of cell migration);GO:0030951(establishment or maintenance of microtubule cytoskeleton polarity);GO:0031647(regulation of protein stability);GO:0031965(nuclear membrane);GO:0034504(protein localization to nucleus);GO:0036498(IRE1-mediated unfolded protein response);GO:0055015(ventricular cardiac muscle cell development);GO:0071456(cellular response to hypoxia);GO:0072201(negative regulation of mesenchymal cell proliferation);GO:0090201(negative regulation of release of cytochrome c from mitochondria);GO:0090343(positive regulation of cell aging);GO:1900114(positive regulation of histone H3-K9 trimethylation);GO:1900180(regulation of protein localization to nucleus);GO:1903243(negative regulation of cardiac muscle hypertrophy in response to stress);GO:2001237(negative regulation of extrinsic apoptotic signaling pathway)","04210(Apoptosis);05410(Hypertrophic cardiomyopathy (HCM));05412(Arrhythmogenic right ventricular cardiomyopathy (ARVC));05414(Dilated cardiomyopathy (DCM))","K12641","NA","lamin A/C [Source:HGNC Symbol;Acc:HGNC:6636]",{"v":2.336126,"d":"2.34"},{"v":1.780095,"d":"1.78"},{"v":2.440468,"d":"2.44"},0,0,0,"inf","inf",{"v":6.63902272609426e-6,"d":"0.00"},{"v":0.00150747309774378,"d":"0.00"},"up","yes"]
[80665,0,"chr17","-",7190448,7219583,"ENST00000399510",22,3289,"ENSG00000132535","DLG4","GO:0000165(MAPK cascade);GO:0002091(negative regulation of receptor internalization);GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0005783(endoplasmic reticulum);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0007165(signal transduction);GO:0007204(positive regulation of cytosolic calcium ion concentration);GO:0007268(chemical synaptic transmission);GO:0007399(nervous system development);GO:0007612(learning);GO:0008021(synaptic vesicle);GO:0008022(protein C-terminus binding);GO:0008076(voltage-gated potassium channel complex);GO:0008328(ionotropic glutamate receptor complex);GO:0014069(postsynaptic density);GO:0016020(membrane);GO:0016188(synaptic vesicle maturation);GO:0019900(kinase binding);GO:0019903(protein phosphatase binding);GO:0030054(cell junction);GO:0030165(PDZ domain binding);GO:0030424(axon);GO:0030425(dendrite);GO:0030666(endocytic vesicle membrane);GO:0030863(cortical cytoskeleton);GO:0031234(extrinsic component of cytoplasmic side of plasma membrane);GO:0031594(neuromuscular junction);GO:0031697(beta-1 adrenergic receptor binding);GO:0031748(D1 dopamine receptor binding);GO:0031812(P2Y1 nucleotide receptor binding);GO:0032281(AMPA glutamate receptor complex);GO:0032839(dendrite cytoplasm);GO:0033130(acetylcholine receptor binding);GO:0035176(social behavior);GO:0035255(ionotropic glutamate receptor binding);GO:0035418(protein localization to synapse);GO:0035641(locomotory exploration behavior);GO:0035865(cellular response to potassium ion);GO:0042995(cell projection);GO:0043005(neuron projection);GO:0043113(receptor clustering);GO:0043197(dendritic spine);GO:0044224(juxtaparanode region of axon);GO:0044300(cerebellar mossy fiber);GO:0044306(neuron projection terminus);GO:0044309(neuron spine);GO:0044877(protein-containing complex binding);GO:0045184(establishment of protein localization);GO:0045202(synapse);GO:0045211(postsynaptic membrane);GO:0048169(regulation of long-term neuronal synaptic plasticity);GO:0050806(positive regulation of synaptic transmission);GO:0050885(neuromuscular process controlling balance);GO:0060076(excitatory synapse);GO:0060997(dendritic spine morphogenesis);GO:0061098(positive regulation of protein tyrosine kinase activity);GO:0065003(protein-containing complex assembly);GO:0071625(vocalization behavior);GO:0071944(cell periphery);GO:0097060(synaptic membrane);GO:0097109(neuroligin family protein binding);GO:0097110(scaffold protein binding);GO:0097113(AMPA glutamate receptor clustering);GO:0097120(receptor localization to synapse);GO:0098609(cell-cell adhesion);GO:0098794(postsynapse);GO:0098839(postsynaptic density membrane);GO:0098970(postsynaptic neurotransmitter receptor diffusion trapping);GO:0098978(glutamatergic synapse);GO:0099645(neurotransmitter receptor localization to postsynaptic specialization membrane);GO:0150012(positive regulation of neuron projection arborization);GO:2000310(regulation of NMDA receptor activity);GO:2000463(positive regulation of excitatory postsynaptic potential);GO:2000821(regulation of grooming behavior)","04390(Hippo signaling pathway);04724(Glutamatergic synapse);05016(Huntington disease);05030(Cocaine addiction)","K11828","NA","discs large MAGUK scaffold protein 4 [Source:HGNC Symbol;Acc:HGNC:2903]",{"v":0.411384,"d":"0.41"},{"v":0.366858,"d":"0.37"},{"v":0.343889,"d":"0.34"},0,0,0,"inf","inf",{"v":6.78736123372563e-6,"d":"0.00"},{"v":0.0015315828175233,"d":"0.00"},"up","yes"]
[101586,0,"chr19","+",21358992,21379302,"ENST00000380870",5,1142,"ENSG00000172687","ZNF738","GO:0000209(protein polyubiquitination);GO:0003676(nucleic acid binding);GO:0003677(DNA binding);GO:0004842(ubiquitin-protein transferase activity);GO:0005622(intracellular);GO:0005634(nucleus);GO:0006355(regulation of transcription, DNA-templated)","NA","NA","NA","zinc finger protein 738 [Source:HGNC Symbol;Acc:HGNC:32469]",{"v":0.891891,"d":"0.89"},{"v":0.959247,"d":"0.96"},{"v":1.430031,"d":"1.43"},0,0,0,"inf","inf",{"v":6.9107396958942e-6,"d":"0.00"},{"v":0.00154979736513479,"d":"0.00"},"up","yes"]
[117763,0,"chr2","-",144388341,144520398,"ENST00000636026",11,5172,"ENSG00000169554","ZEB2","GO:0000122(negative regulation of transcription by RNA polymerase II);GO:0000790(nuclear chromatin);GO:0000981(DNA-binding transcription factor activity, RNA polymerase II-specific);GO:0001227(DNA-binding transcription repressor activity, RNA polymerase II-specific);GO:0001228(DNA-binding transcription activator activity, RNA polymerase II-specific);GO:0001755(neural crest cell migration);GO:0001756(somitogenesis);GO:0001843(neural tube closure);GO:0003676(nucleic acid binding);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005730(nucleolus);GO:0005829(cytosol);GO:0007399(nervous system development);GO:0007417(central nervous system development);GO:0019208(phosphatase regulator activity);GO:0021540(corpus callosum morphogenesis);GO:0021766(hippocampus development);GO:0021846(cell proliferation in forebrain);GO:0021957(corticospinal tract morphogenesis);GO:0030177(positive regulation of Wnt signaling pathway);GO:0043507(positive regulation of JUN kinase activity);GO:0043565(sequence-specific DNA binding);GO:0045636(positive regulation of melanocyte differentiation);GO:0045944(positive regulation of transcription by RNA polymerase II);GO:0046872(metal ion binding);GO:0048023(positive regulation of melanin biosynthetic process);GO:0048066(developmental pigmentation);GO:0048598(embryonic morphogenesis);GO:0048668(collateral sprouting);GO:0050772(positive regulation of axonogenesis);GO:0061373(mammillary axonal complex development);GO:0070412(R-SMAD binding);GO:0097324(melanocyte migration);GO:1902748(positive regulation of lens fiber cell differentiation);GO:1903056(regulation of melanosome organization)","05206(MicroRNAs in cancer)","K09299","NA","zinc finger E-box binding homeobox 2 [Source:HGNC Symbol;Acc:HGNC:14881]",{"v":0.000815,"d":"0.00"},{"v":5.323975,"d":"5.32"},{"v":4.919284,"d":"4.92"},0,0,{"v":0.006143,"d":"0.01"},{"v":1667.60117206577,"d":"1667.60"},{"v":10.7035585759129,"d":"10.70"},{"v":6.98960827444653e-6,"d":"0.00"},{"v":0.00155786790558676,"d":"0.00"},"up","yes"]
[50282,0,"chr13","-",19702871,19783019,"ENST00000619300",10,2013,"ENSG00000121390","PSPC1","GO:0000976(transcription regulatory region sequence-specific DNA binding);GO:0000981(DNA-binding transcription factor activity, RNA polymerase II-specific);GO:0001650(fibrillar center);GO:0002218(activation of innate immune response);GO:0002376(immune system process);GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005730(nucleolus);GO:0005737(cytoplasm);GO:0006357(regulation of transcription by RNA polymerase II);GO:0016363(nuclear matrix);GO:0016607(nuclear speck);GO:0042382(paraspeckles);GO:0042752(regulation of circadian rhythm);GO:0045087(innate immune response);GO:0045892(negative regulation of transcription, DNA-templated);GO:0048511(rhythmic process);GO:0070888(E-box binding)","NA","NA","NA","paraspeckle component 1 [Source:HGNC Symbol;Acc:HGNC:20320]",{"v":7.142584,"d":"7.14"},{"v":0.000169,"d":"0.00"},{"v":5.556419,"d":"5.56"},{"v":0.000437,"d":"0.00"},{"v":0.000247,"d":"0.00"},{"v":0.000646,"d":"0.00"},{"v":9548.24962406015,"d":"9548.25"},{"v":13.2210205685814,"d":"13.22"},{"v":7.40396636970404e-6,"d":"0.00"},{"v":0.00163783689230011,"d":"0.00"},"up","yes"]
[44130,0,"chr12","+",56021043,56038435,"ENST00000547167",8,5313,"ENSG00000123411","IKZF4","GO:0000981(DNA-binding transcription factor activity, RNA polymerase II-specific);GO:0003676(nucleic acid binding);GO:0003677(DNA binding);GO:0003700(DNA-binding transcription factor activity);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0008270(zinc ion binding);GO:0016604(nuclear body);GO:0019904(protein domain specific binding);GO:0032991(protein-containing complex);GO:0043425(bHLH transcription factor binding);GO:0043565(sequence-specific DNA binding);GO:0044212(transcription regulatory region DNA binding);GO:0045892(negative regulation of transcription, DNA-templated);GO:0045944(positive regulation of transcription by RNA polymerase II);GO:0046872(metal ion binding);GO:0051260(protein homooligomerization);GO:0051291(protein heterooligomerization)","NA","K09220","NA","IKAROS family zinc finger 4 [Source:HGNC Symbol;Acc:HGNC:13179]",{"v":0.180518,"d":"0.18"},{"v":0.313815,"d":"0.31"},{"v":0.206277,"d":"0.21"},0,0,0,"inf","inf",{"v":7.43856557196581e-6,"d":"0.00"},{"v":0.00163783689230011,"d":"0.00"},"up","yes"]
[196481,0,"chr9","+",69204798,69254520,"ENST00000535702",22,3984,"ENSG00000119139","TJP2","GO:0004385(guanylate kinase activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0005912(adherens junction);GO:0005923(bicellular tight junction);GO:0016020(membrane);GO:0019904(protein domain specific binding);GO:0030054(cell junction);GO:0030674(protein binding, bridging);GO:0035329(hippo signaling);GO:0045296(cadherin binding);GO:0046037(GMP metabolic process);GO:0046710(GDP metabolic process);GO:0050892(intestinal absorption);GO:0090557(establishment of endothelial intestinal barrier);GO:0090559(regulation of membrane permeability)","04530(Tight junction);05110(Vibrio cholerae infection)","K06098","NA","tight junction protein 2 [Source:HGNC Symbol;Acc:HGNC:11828]",{"v":3.761484,"d":"3.76"},0,{"v":2.80716,"d":"2.81"},0,0,0,"inf","inf",{"v":7.53994678925972e-6,"d":"0.00"},{"v":0.00165015823405907,"d":"0.00"},"up","yes"]
[60634,0,"chr14","-",102348282,102362890,"ENST00000216756",5,953,"ENSG00000100865","CINP","GO:0005515(protein binding);GO:0005634(nucleus);GO:0006260(DNA replication);GO:0006281(DNA repair);GO:0006974(cellular response to DNA damage stimulus);GO:0007049(cell cycle);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0051301(cell division)","NA","NA","NA","cyclin dependent kinase 2 interacting protein [Source:HGNC Symbol;Acc:HGNC:23789]",{"v":4.664768,"d":"4.66"},{"v":3.821618,"d":"3.82"},{"v":3.933052,"d":"3.93"},{"v":0.01623,"d":"0.02"},{"v":0.011909,"d":"0.01"},{"v":0.135739,"d":"0.14"},{"v":75.7846568788977,"d":"75.78"},{"v":6.24383388938781,"d":"6.24"},{"v":7.72044394427704e-6,"d":"0.00"},{"v":0.0016795432844047,"d":"0.00"},"up","yes"]
[2231,0,"chr1","-",18871432,18902528,"ENST00000538839",14,2957,"ENSG00000159423","ALDH4A1","GO:0003842(1-pyrroline-5-carboxylate dehydrogenase activity);GO:0004029(aldehyde dehydrogenase (NAD) activity);GO:0005739(mitochondrion);GO:0005759(mitochondrial matrix);GO:0006560(proline metabolic process);GO:0006562(proline catabolic process);GO:0009055(electron transfer activity);GO:0010133(proline catabolic process to glutamate);GO:0016491(oxidoreductase activity);GO:0016620(oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor);GO:0019470(4-hydroxyproline catabolic process);GO:0022900(electron transport chain);GO:0042802(identical protein binding);GO:0046487(glyoxylate metabolic process);GO:0055114(oxidation-reduction process)","00250(Alanine, aspartate and glutamate metabolism);00330(Arginine and proline metabolism)","K00294","EC:1.2.1.88","aldehyde dehydrogenase 4 family member A1 [Source:HGNC Symbol;Acc:HGNC:406]",{"v":3.882623,"d":"3.88"},{"v":4.645321,"d":"4.65"},0,0,0,0,"inf","inf",{"v":7.99432127769829e-6,"d":"0.00"},{"v":0.00171813751757694,"d":"0.00"},"up","yes"]
[7114,0,"chr1","+",65264754,65415869,"ENST00000395325",19,5743,"ENSG00000116675","DNAJC6","GO:0004721(phosphoprotein phosphatase activity);GO:0004725(protein tyrosine phosphatase activity);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0006470(protein dephosphorylation);GO:0006898(receptor-mediated endocytosis);GO:0014069(postsynaptic density);GO:0016191(synaptic vesicle uncoating);GO:0016787(hydrolase activity);GO:0017124(SH3 domain binding);GO:0030276(clathrin binding);GO:0031982(vesicle);GO:0035335(peptidyl-tyrosine dephosphorylation);GO:0043231(intracellular membrane-bounded organelle);GO:0045202(synapse);GO:0061024(membrane organization);GO:0072318(clathrin coat disassembly);GO:0072583(clathrin-dependent endocytosis);GO:0098793(presynapse);GO:2000369(regulation of clathrin-dependent endocytosis)","04144(Endocytosis)","K09526","NA","DnaJ heat shock protein family (Hsp40) member C6 [Source:HGNC Symbol;Acc:HGNC:15469]",0,0,0,{"v":1.992235,"d":"1.99"},{"v":2.323706,"d":"2.32"},0,"-inf","-inf",{"v":8.00105838202418e-6,"d":"0.00"},{"v":0.00171813751757694,"d":"0.00"},"down","yes"]
[160773,0,"chr5","-",88718274,88883184,"ENST00000637481",10,6088,"ENSG00000081189","MEF2C","GO:0000122(negative regulation of transcription by RNA polymerase II);GO:0000165(MAPK cascade);GO:0000790(nuclear chromatin);GO:0000977(RNA polymerase II regulatory region sequence-specific DNA binding);GO:0000978(RNA polymerase II proximal promoter sequence-specific DNA binding);GO:0000980(RNA polymerase II distal enhancer sequence-specific DNA binding);GO:0000981(DNA-binding transcription factor activity, RNA polymerase II-specific);GO:0000987(proximal promoter sequence-specific DNA binding);GO:0001228(DNA-binding transcription activator activity, RNA polymerase II-specific);GO:0001568(blood vessel development);GO:0001649(osteoblast differentiation);GO:0001764(neuron migration);GO:0001782(B cell homeostasis);GO:0001947(heart looping);GO:0001958(endochondral ossification);GO:0001974(blood vessel remodeling);GO:0002062(chondrocyte differentiation);GO:0002467(germinal center formation);GO:0002634(regulation of germinal center formation);GO:0002931(response to ischemia);GO:0003138(primary heart field specification);GO:0003139(secondary heart field specification);GO:0003151(outflow tract morphogenesis);GO:0003185(sinoatrial valve morphogenesis);GO:0003211(cardiac ventricle formation);GO:0003677(DNA binding);GO:0003680(AT DNA binding);GO:0003682(chromatin binding);GO:0003700(DNA-binding transcription factor activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0006355(regulation of transcription, DNA-templated);GO:0006915(apoptotic process);GO:0006959(humoral immune response);GO:0007275(multicellular organism development);GO:0007399(nervous system development);GO:0007507(heart development);GO:0007517(muscle organ development);GO:0007519(skeletal muscle tissue development);GO:0007521(muscle cell fate determination);GO:0007611(learning or memory);GO:0010628(positive regulation of gene expression);GO:0010629(negative regulation of gene expression);GO:0010694(positive regulation of alkaline phosphatase activity);GO:0014033(neural crest cell differentiation);GO:0014898(cardiac muscle hypertrophy in response to stress);GO:0014902(myotube differentiation);GO:0016528(sarcoplasm);GO:0016607(nuclear speck);GO:0030154(cell differentiation);GO:0030182(neuron differentiation);GO:0030220(platelet formation);GO:0030224(monocyte differentiation);GO:0030279(negative regulation of ossification);GO:0030318(melanocyte differentiation);GO:0030501(positive regulation of bone mineralization);GO:0030890(positive regulation of B cell proliferation);GO:0032991(protein-containing complex);GO:0033613(activating transcription factor binding);GO:0035690(cellular response to drug);GO:0035914(skeletal muscle cell differentiation);GO:0035984(cellular response to trichostatin A);GO:0042100(B cell proliferation);GO:0042826(histone deacetylase binding);GO:0043231(intracellular membrane-bounded organelle);GO:0043406(positive regulation of MAP kinase activity);GO:0043523(regulation of neuron apoptotic process);GO:0043524(negative regulation of neuron apoptotic process);GO:0043537(negative regulation of blood vessel endothelial cell migration);GO:0043565(sequence-specific DNA binding);GO:0044212(transcription regulatory region DNA binding);GO:0045165(cell fate commitment);GO:0045652(regulation of megakaryocyte differentiation);GO:0045663(positive regulation of myoblast differentiation);GO:0045666(positive regulation of neuron differentiation);GO:0045669(positive regulation of osteoblast differentiation);GO:0045893(positive regulation of transcription, DNA-templated);GO:0045944(positive regulation of transcription by RNA polymerase II);GO:0046928(regulation of neurotransmitter secretion);GO:0046982(protein heterodimerization activity);GO:0046983(protein dimerization activity);GO:0048167(regulation of synaptic plasticity);GO:0048643(positive regulation of skeletal muscle tissue development);GO:0048666(neuron development);GO:0048667(cell morphogenesis involved in neuron differentiation);GO:0048703(embryonic viscerocranium morphogenesis);GO:0048704(embryonic skeletal system morphogenesis);GO:0050680(negative regulation of epithelial cell proliferation);GO:0050853(B cell receptor signaling pathway);GO:0051145(smooth muscle cell differentiation);GO:0051149(positive regulation of muscle cell differentiation);GO:0051963(regulation of synapse assembly);GO:0051966(regulation of synaptic transmission, glutamatergic);GO:0055007(cardiac muscle cell differentiation);GO:0055012(ventricular cardiac muscle cell differentiation);GO:0060021(roof of mouth development);GO:0060025(regulation of synaptic activity);GO:0060045(positive regulation of cardiac muscle cell proliferation);GO:0060079(excitatory postsynaptic potential);GO:0060297(regulation of sarcomere organization);GO:0060536(cartilage morphogenesis);GO:0060998(regulation of dendritic spine development);GO:0061333(renal tubule morphogenesis);GO:0071222(cellular response to lipopolysaccharide);GO:0071277(cellular response to calcium ion);GO:0071374(cellular response to parathyroid hormone stimulus);GO:0071498(cellular response to fluid shear stress);GO:0071560(cellular response to transforming growth factor beta stimulus);GO:0071837(HMG box domain binding);GO:0071864(positive regulation of cell proliferation in bone marrow);GO:0072102(glomerulus morphogenesis);GO:0072160(nephron tubule epithelial cell differentiation);GO:0090073(positive regulation of protein homodimerization activity);GO:0098794(postsynapse);GO:1904706(negative regulation of vascular smooth muscle cell proliferation);GO:1904753(negative regulation of vascular associated smooth muscle cell migration);GO:1905563(negative regulation of vascular endothelial cell proliferation);GO:2000111(positive regulation of macrophage apoptotic process);GO:2000310(regulation of NMDA receptor activity);GO:2000311(regulation of AMPA receptor activity);GO:2000727(positive regulation of cardiac muscle cell differentiation);GO:2000987(positive regulation of behavioral fear response);GO:2001013(epithelial cell proliferation involved in renal tubule morphogenesis);GO:2001016(positive regulation of skeletal muscle cell differentiation)","04010(MAPK signaling pathway);04022(cGMP-PKG signaling pathway);04371(Apelin signaling pathway);04921(Oxytocin signaling pathway);04928(Parathyroid hormone synthesis, secretion and action);05202(Transcriptional misregulation in cancer);05418(Fluid shear stress and atherosclerosis)","K04454","NA","myocyte enhancer factor 2C [Source:HGNC Symbol;Acc:HGNC:6996]",0,{"v":1.950699,"d":"1.95"},{"v":2.195925,"d":"2.20"},0,0,0,"inf","inf",{"v":8.03972964459346e-6,"d":"0.00"},{"v":0.00171813751757694,"d":"0.00"},"up","yes"]
[197915,0,"chr9","+",98943907,99070787,"ENST00000375001",42,5223,"ENSG00000204291","COL15A1","GO:0001525(angiogenesis);GO:0005198(structural molecule activity);GO:0005201(extracellular matrix structural constituent);GO:0005576(extracellular region);GO:0005581(collagen trimer);GO:0005582(collagen type XV trimer);GO:0005604(basement membrane);GO:0005615(extracellular space);GO:0005788(endoplasmic reticulum lumen);GO:0007155(cell adhesion);GO:0007165(signal transduction);GO:0007275(multicellular organism development);GO:0016021(integral component of membrane);GO:0030020(extracellular matrix structural constituent conferring tensile strength);GO:0030154(cell differentiation);GO:0030198(extracellular matrix organization);GO:0030574(collagen catabolic process);GO:0031012(extracellular matrix);GO:0062023(collagen-containing extracellular matrix);GO:0070062(extracellular exosome)","04974(Protein digestion and absorption)","K08135","NA","collagen type XV alpha 1 chain [Source:HGNC Symbol;Acc:HGNC:2192]",{"v":7.924612,"d":"7.92"},{"v":10.873087,"d":"10.87"},{"v":9.273208,"d":"9.27"},{"v":73.859657,"d":"73.86"},{"v":71.329689,"d":"71.33"},{"v":64.515327,"d":"64.52"},{"v":0.13385923450547,"d":"0.13"},{"v":-2.90121142572043,"d":"-2.90"},{"v":8.34933080353386e-6,"d":"0.00"},{"v":0.00177386659703149,"d":"0.00"},"down","yes"]
[57299,0,"chr14","+",60981293,61083729,"ENST00000451406",17,1568,"ENSG00000139974","SLC38A6","GO:0003333(amino acid transmembrane transport);GO:0005886(plasma membrane);GO:0005887(integral component of plasma membrane);GO:0006811(ion transport);GO:0006814(sodium ion transport);GO:0006865(amino acid transport);GO:0015171(amino acid transmembrane transporter activity);GO:0016020(membrane);GO:0016021(integral component of membrane)","NA","K14993","NA","solute carrier family 38 member 6 [Source:HGNC Symbol;Acc:HGNC:19863]",0,{"v":6.944384,"d":"6.94"},{"v":8.859676,"d":"8.86"},0,0,0,"inf","inf",{"v":8.41156899188906e-6,"d":"0.00"},{"v":0.00177669942718215,"d":"0.00"},"up","yes"]
[14164,0,"chr1","-",173931214,173993064,"ENST00000258349",19,10988,"ENSG00000135870","RC3H1","GO:0000209(protein polyubiquitination);GO:0000288(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay);GO:0000932(P-body);GO:0000956(nuclear-transcribed mRNA catabolic process);GO:0001782(B cell homeostasis);GO:0002634(regulation of germinal center formation);GO:0002635(negative regulation of germinal center formation);GO:0003723(RNA binding);GO:0003725(double-stranded RNA binding);GO:0003729(mRNA binding);GO:0003730(mRNA 3'-UTR binding);GO:0004842(ubiquitin-protein transferase activity);GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0008270(zinc ion binding);GO:0010468(regulation of gene expression);GO:0010494(cytoplasmic stress granule);GO:0010608(posttranscriptional regulation of gene expression);GO:0016567(protein ubiquitination);GO:0016740(transferase activity);GO:0030889(negative regulation of B cell proliferation);GO:0033962(cytoplasmic mRNA processing body assembly);GO:0035198(miRNA binding);GO:0035613(RNA stem-loop binding);GO:0042098(T cell proliferation);GO:0042129(regulation of T cell proliferation);GO:0043029(T cell homeostasis);GO:0043488(regulation of mRNA stability);GO:0045623(negative regulation of T-helper cell differentiation);GO:0046007(negative regulation of activated T cell proliferation);GO:0046872(metal ion binding);GO:0048535(lymph node development);GO:0048536(spleen development);GO:0050852(T cell receptor signaling pathway);GO:0050856(regulation of T cell receptor signaling pathway);GO:0050863(regulation of T cell activation);GO:0061014(positive regulation of mRNA catabolic process);GO:0061158(3'-UTR-mediated mRNA destabilization);GO:0061470(T follicular helper cell differentiation);GO:0061630(ubiquitin protein ligase activity);GO:0071347(cellular response to interleukin-1);GO:1901224(positive regulation of NIK/NF-kappaB signaling);GO:2000320(negative regulation of T-helper 17 cell differentiation);GO:2000628(regulation of miRNA metabolic process)","NA","K15690","NA","ring finger and CCCH-type domains 1 [Source:HGNC Symbol;Acc:HGNC:29434]",0,0,0,{"v":0.488443,"d":"0.49"},0,{"v":1.929957,"d":"1.93"},"-inf","-inf",{"v":8.58653903357629e-6,"d":"0.00"},{"v":0.00180317319705102,"d":"0.00"},"down","yes"]
[154015,0,"chr4","+",108620569,108625554,"ENST00000502534",6,560,"ENSG00000109475","RPL34","GO:0000184(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay);GO:0003723(RNA binding);GO:0003735(structural constituent of ribosome);GO:0005622(intracellular);GO:0005737(cytoplasm);GO:0005783(endoplasmic reticulum);GO:0005829(cytosol);GO:0005840(ribosome);GO:0006412(translation);GO:0006413(translational initiation);GO:0006614(SRP-dependent cotranslational protein targeting to membrane);GO:0019083(viral transcription);GO:0022625(cytosolic large ribosomal subunit);GO:0045296(cadherin binding);GO:0070062(extracellular exosome)","03010(Ribosome)","K02915","NA","ribosomal protein L34 [Source:HGNC Symbol;Acc:HGNC:10340]",0,{"v":0.018671,"d":"0.02"},0,{"v":0.060069,"d":"0.06"},{"v":7.520783,"d":"7.52"},{"v":9.298198,"d":"9.30"},{"v":0.00110616415023357,"d":"0.00"},{"v":-9.82021879316216,"d":"-9.82"},{"v":8.96205779300662e-6,"d":"0.00"},{"v":0.00187121585988466,"d":"0.00"},"down","yes"]
[182431,0,"chr7","-",102483344,102543764,"ENST00000481893",26,3569,"ENSG00000272949","AC093668","GO:0016020(membrane);GO:0016021(integral component of membrane)","NA","NA","NA","novel transcript",{"v":3.222141,"d":"3.22"},{"v":2.198042,"d":"2.20"},{"v":3.239952,"d":"3.24"},{"v":0.027903,"d":"0.03"},{"v":0.094372,"d":"0.09"},{"v":0.00184,"d":"0.00"},{"v":69.7750876203521,"d":"69.78"},{"v":6.12464012585005,"d":"6.12"},{"v":9.18057719445721e-6,"d":"0.00"},{"v":0.00189912749198484,"d":"0.00"},"up","yes"]
[95389,0,"chr18","-",62044634,62187079,"ENST00000638936",30,4233,"ENSG00000197563","PIGN","GO:0003824(catalytic activity);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0006506(GPI anchor biosynthetic process);GO:0008484(sulfuric ester hydrolase activity);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016254(preassembly of GPI anchor in ER membrane);GO:0016740(transferase activity);GO:0051377(mannose-ethanolamine phosphotransferase activity)","00563(Glycosylphosphatidylinositol (GPI)-anchor biosynthesis)","K05285","EC:2.7.-.-","phosphatidylinositol glycan anchor biosynthesis class N [Source:HGNC Symbol;Acc:HGNC:8967]",0,0,0,{"v":2.9e-5,"d":"0.00"},{"v":0.832944,"d":"0.83"},{"v":1.664243,"d":"1.66"},"-inf","-inf",{"v":9.23727782741037e-6,"d":"0.00"},{"v":0.00189912749198484,"d":"0.00"},"down","yes"]
[117335,0,"chr2","+",131107556,131147797,"ENST00000409612",8,2210,"ENSG00000115762","PLEKHB2","GO:0005515(protein binding);GO:0005547(phosphatidylinositol-3,4,5-trisphosphate binding);GO:0005768(endosome);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0045595(regulation of cell differentiation);GO:0055038(recycling endosome membrane)","NA","NA","NA","pleckstrin homology domain containing B2 [Source:HGNC Symbol;Acc:HGNC:19236]",{"v":0.018209,"d":"0.02"},{"v":1.815046,"d":"1.82"},{"v":1.013104,"d":"1.01"},0,0,0,"inf","inf",{"v":9.25256168679651e-6,"d":"0.00"},{"v":0.00189912749198484,"d":"0.00"},"up","yes"]
[67291,0,"chr15","+",80072583,80138358,"ENST00000559775",7,1602,"ENSG00000086666","ZFAND6","GO:0003674(molecular_function);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0005575(cellular_component);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0006625(protein targeting to peroxisome);GO:0006915(apoptotic process);GO:0008270(zinc ion binding);GO:0015031(protein transport);GO:0031593(polyubiquitin modification-dependent protein binding);GO:0043066(negative regulation of apoptotic process);GO:0043122(regulation of I-kappaB kinase/NF-kappaB signaling);GO:0046872(metal ion binding);GO:0071356(cellular response to tumor necrosis factor)","NA","NA","NA","zinc finger AN1-type containing 6 [Source:HGNC Symbol;Acc:HGNC:30164]",{"v":2.362076,"d":"2.36"},{"v":2.880965,"d":"2.88"},{"v":1.924177,"d":"1.92"},0,0,{"v":0.045396,"d":"0.05"},{"v":157.88214820689,"d":"157.88"},{"v":7.30270424413069,"d":"7.30"},{"v":9.35936689231764e-6,"d":"0.00"},{"v":0.00190181608574066,"d":"0.00"},"up","yes"]
[46024,0,"chr12","+",78036257,78211465,"ENST00000644176",29,7084,"ENSG00000067798","NAV3","GO:0005515(protein binding);GO:0005524(ATP binding);GO:0005634(nucleus);GO:0005640(nuclear outer membrane);GO:0007026(negative regulation of microtubule depolymerization);GO:0007399(nervous system development);GO:0008017(microtubule binding);GO:0016020(membrane);GO:0022008(neurogenesis);GO:0030336(negative regulation of cell migration);GO:0031116(positive regulation of microtubule polymerization);GO:0032703(negative regulation of interleukin-2 production);GO:1905929(positive regulation of invadopodium disassembly);GO:1990752(microtubule end)","NA","NA","NA","neuron navigator 3 [Source:HGNC Symbol;Acc:HGNC:15998]",0,0,0,{"v":0.197448,"d":"0.20"},{"v":0.195864,"d":"0.20"},{"v":0.104599,"d":"0.10"},"-inf","-inf",{"v":9.39727507549367e-6,"d":"0.00"},{"v":0.00190181608574066,"d":"0.00"},"down","yes"]
[127270,0,"chr20","+",45416154,45425826,"ENST00000545755",7,1158,"ENSG00000124155","PIGT","GO:0003923(GPI-anchor transamidase activity);GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0006506(GPI anchor biosynthetic process);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016255(attachment of GPI anchor to protein);GO:0030176(integral component of endoplasmic reticulum membrane);GO:0030182(neuron differentiation);GO:0031410(cytoplasmic vesicle);GO:0042765(GPI-anchor transamidase complex);GO:0051402(neuron apoptotic process)","00563(Glycosylphosphatidylinositol (GPI)-anchor biosynthesis)","K05292","NA","phosphatidylinositol glycan anchor biosynthesis class T [Source:HGNC Symbol;Acc:HGNC:14938]",0,0,0,0,{"v":3.900341,"d":"3.90"},{"v":22.065138,"d":"22.07"},"-inf","-inf",{"v":9.45508110344839e-6,"d":"0.00"},{"v":0.00190181608574066,"d":"0.00"},"down","yes"]
[79563,0,"chr17","-",1494757,1516735,"ENST00000320345",13,2880,"ENSG00000132376","INPP5K","GO:0001701(in utero embryonic development);GO:0001726(ruffle);GO:0001933(negative regulation of protein phosphorylation);GO:0004439(phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity);GO:0004445(inositol-polyphosphate 5-phosphatase activity);GO:0005000(vasopressin receptor activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005783(endoplasmic reticulum);GO:0005802(trans-Golgi network);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0005979(regulation of glycogen biosynthetic process);GO:0006469(negative regulation of protein kinase activity);GO:0006661(phosphatidylinositol biosynthetic process);GO:0007186(G protein-coupled receptor signaling pathway);GO:0010801(negative regulation of peptidyl-threonine phosphorylation);GO:0010829(negative regulation of glucose transmembrane transport);GO:0016020(membrane);GO:0016311(dephosphorylation);GO:0016312(inositol bisphosphate phosphatase activity);GO:0016787(hydrolase activity);GO:0030036(actin cytoskeleton organization);GO:0032587(ruffle membrane);GO:0032868(response to insulin);GO:0032869(cellular response to insulin stimulus);GO:0032870(cellular response to hormone stimulus);GO:0033137(negative regulation of peptidyl-serine phosphorylation);GO:0034485(phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity);GO:0034594(phosphatidylinositol trisphosphate phosphatase activity);GO:0034595(phosphatidylinositol phosphate 5-phosphatase activity);GO:0035305(negative regulation of dephosphorylation);GO:0035810(positive regulation of urine volume);GO:0042577(lipid phosphatase activity);GO:0042593(glucose homeostasis);GO:0043005(neuron projection);GO:0043407(negative regulation of MAP kinase activity);GO:0043922(negative regulation by host of viral transcription);GO:0045719(negative regulation of glycogen biosynthetic process);GO:0045869(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate);GO:0045892(negative regulation of transcription, DNA-templated);GO:0045893(positive regulation of transcription, DNA-templated);GO:0046030(inositol trisphosphate phosphatase activity);GO:0046627(negative regulation of insulin receptor signaling pathway);GO:0046855(inositol phosphate dephosphorylation);GO:0046856(phosphatidylinositol dephosphorylation);GO:0048471(perinuclear region of cytoplasm);GO:0051497(negative regulation of stress fiber assembly);GO:0051898(negative regulation of protein kinase B signaling);GO:0051926(negative regulation of calcium ion transport);GO:0052658(inositol-1,4,5-trisphosphate 5-phosphatase activity);GO:0052659(inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity);GO:0071320(cellular response to cAMP);GO:0071356(cellular response to tumor necrosis factor);GO:0071364(cellular response to epidermal growth factor stimulus);GO:0072659(protein localization to plasma membrane);GO:0090315(negative regulation of protein targeting to membrane);GO:0097178(ruffle assembly);GO:2000466(negative regulation of glycogen (starch) synthase activity);GO:2001153(positive regulation of renal water transport)","00562(Inositol phosphate metabolism);04070(Phosphatidylinositol signaling system);04910(Insulin signaling pathway)","K01106","EC:3.1.3.56","inositol polyphosphate-5-phosphatase K [Source:HGNC Symbol;Acc:HGNC:33882]",0,0,0,{"v":1.808966,"d":"1.81"},0,{"v":6.908272,"d":"6.91"},"-inf","-inf",{"v":9.47505399171648e-6,"d":"0.00"},{"v":0.00190181608574066,"d":"0.00"},"down","yes"]
[112869,0,"chr2","-",61868125,61888671,"ENST00000544079",13,2261,"ENSG00000115484","CCT4","GO:0000166(nucleotide binding);GO:0002199(zona pellucida receptor complex);GO:0003723(RNA binding);GO:0005515(protein binding);GO:0005524(ATP binding);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0005813(centrosome);GO:0005815(microtubule organizing center);GO:0005829(cytosol);GO:0005832(chaperonin-containing T-complex);GO:0005856(cytoskeleton);GO:0005874(microtubule);GO:0006457(protein folding);GO:0007339(binding of sperm to zona pellucida);GO:0032212(positive regulation of telomere maintenance via telomerase);GO:0042470(melanosome);GO:0042995(cell projection);GO:0044297(cell body);GO:0050821(protein stabilization);GO:0051082(unfolded protein binding);GO:0051973(positive regulation of telomerase activity);GO:0070062(extracellular exosome);GO:0090666(scaRNA localization to Cajal body);GO:1901998(toxin transport);GO:1904851(positive regulation of establishment of protein localization to telomere);GO:1904871(positive regulation of protein localization to Cajal body);GO:1904874(positive regulation of telomerase RNA localization to Cajal body)","NA","K09496","NA","chaperonin containing TCP1 subunit 4 [Source:HGNC Symbol;Acc:HGNC:1617]",{"v":10.670089,"d":"10.67"},{"v":13.410022,"d":"13.41"},{"v":9.38901,"d":"9.39"},0,{"v":0.178686,"d":"0.18"},0,{"v":187.306901492003,"d":"187.31"},{"v":7.54926024773717,"d":"7.55"},{"v":9.84086157550208e-6,"d":"0.00"},{"v":0.00196438736834061,"d":"0.00"},"up","yes"]
[154566,0,"chr4","-",121879027,121933457,"ENST00000264811",11,3675,"ENSG00000138741","TRPC3","GO:0005216(ion channel activity);GO:0005262(calcium channel activity);GO:0005515(protein binding);GO:0005886(plasma membrane);GO:0005887(integral component of plasma membrane);GO:0006811(ion transport);GO:0006816(calcium ion transport);GO:0006828(manganese ion transport);GO:0007338(single fertilization);GO:0007602(phototransduction);GO:0010524(positive regulation of calcium ion transport into cytosol);GO:0015279(store-operated calcium channel activity);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0030168(platelet activation);GO:0033198(response to ATP);GO:0034703(cation channel complex);GO:0051480(regulation of cytosolic calcium ion concentration);GO:0051592(response to calcium ion);GO:0055085(transmembrane transport);GO:0070588(calcium ion transmembrane transport);GO:0070679(inositol 1,4,5 trisphosphate binding);GO:1903244(positive regulation of cardiac muscle hypertrophy in response to stress)","04360(Axon guidance)","K04966","NA","transient receptor potential cation channel subfamily C member 3 [Source:HGNC Symbol;Acc:HGNC:12335]",{"v":0.145074,"d":"0.15"},{"v":0.314171,"d":"0.31"},{"v":0.603068,"d":"0.60"},0,0,0,"inf","inf",{"v":1.00030730485289e-5,"d":"0.00"},{"v":0.0019858559773391,"d":"0.00"},"up","yes"]
[8253,0,"chr1","+",92168923,92184723,"ENST00000637221",7,4272,"ENSG00000189195","BTBD8","GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0098793(presynapse);GO:0150007(clathrin-dependent synaptic vesicle endocytosis)","NA","K10480","NA","BTB domain containing 8 [Source:HGNC Symbol;Acc:HGNC:21019]",{"v":0.770193,"d":"0.77"},{"v":0.06666,"d":"0.07"},{"v":0.247031,"d":"0.25"},0,0,0,"inf","inf",{"v":1.0365385743475e-5,"d":"0.00"},{"v":0.0020466003481546,"d":"0.00"},"up","yes"]
[36015,0,"chr11","-",108472112,108491504,"ENST00000434945",7,4374,"ENSG00000178202","KDELC2","GO:0005515(protein binding);GO:0005575(cellular_component);GO:0005783(endoplasmic reticulum);GO:0005788(endoplasmic reticulum lumen);GO:0006486(protein glycosylation);GO:0016740(transferase activity);GO:0016757(transferase activity, transferring glycosyl groups);GO:0018242(protein O-linked glycosylation via serine);GO:0030158(protein xylosyltransferase activity);GO:0035251(UDP-glucosyltransferase activity);GO:0035252(UDP-xylosyltransferase activity);GO:0046527(glucosyltransferase activity)","NA","NA","NA","KDEL motif containing 2 [Source:HGNC Symbol;Acc:HGNC:28496]",{"v":27.697668,"d":"27.70"},{"v":25.749016,"d":"25.75"},{"v":0.698234,"d":"0.70"},{"v":0.417732,"d":"0.42"},{"v":0.308285,"d":"0.31"},{"v":0.013808,"d":"0.01"},{"v":73.1861156354543,"d":"73.19"},{"v":6.19349807121337,"d":"6.19"},{"v":1.05033676705859e-5,"d":"0.00"},{"v":0.00206263431066154,"d":"0.00"},"up","yes"]
[194597,0,"chr9","-",13105710,13279564,"ENST00000541718",46,7603,"ENSG00000107186","MPDZ","GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0005886(plasma membrane);GO:0005923(bicellular tight junction);GO:0007155(cell adhesion);GO:0008022(protein C-terminus binding);GO:0014069(postsynaptic density);GO:0016020(membrane);GO:0016032(viral process);GO:0016324(apical plasma membrane);GO:0016327(apicolateral plasma membrane);GO:0030054(cell junction);GO:0030425(dendrite);GO:0031410(cytoplasmic vesicle);GO:0042995(cell projection);GO:0043005(neuron projection);GO:0043220(Schmidt-Lanterman incisure);GO:0045202(synapse);GO:0045211(postsynaptic membrane)","04530(Tight junction)","K06095","NA","multiple PDZ domain crumbs cell polarity complex component [Source:HGNC Symbol;Acc:HGNC:7208]",0,0,0,{"v":0.605752,"d":"0.61"},0,{"v":2.531198,"d":"2.53"},"-inf","-inf",{"v":1.07842653700843e-5,"d":"0.00"},{"v":0.00210641054244712,"d":"0.00"},"down","yes"]
[152430,0,"chr4","+",77511753,77611834,"ENST00000286758",5,1203,"ENSG00000156234","CXCL13","GO:0002467(germinal center formation);GO:0002518(lymphocyte chemotaxis across high endothelial venule);GO:0002544(chronic inflammatory response);GO:0002920(regulation of humoral immune response);GO:0005125(cytokine activity);GO:0005576(extracellular region);GO:0005615(extracellular space);GO:0005623(cell);GO:0006935(chemotaxis);GO:0006952(defense response);GO:0006954(inflammatory response);GO:0006955(immune response);GO:0007166(cell surface receptor signaling pathway);GO:0007186(G protein-coupled receptor signaling pathway);GO:0007204(positive regulation of cytosolic calcium ion concentration);GO:0007267(cell-cell signaling);GO:0008009(chemokine activity);GO:0008201(heparin binding);GO:0010469(regulation of signaling receptor activity);GO:0010820(positive regulation of T cell chemotaxis);GO:0017134(fibroblast growth factor binding);GO:0030593(neutrophil chemotaxis);GO:0030595(leukocyte chemotaxis);GO:0031724(CXCR5 chemokine receptor binding);GO:0031735(CCR10 chemokine receptor binding);GO:0033625(positive regulation of integrin activation);GO:0033634(positive regulation of cell-cell adhesion mediated by integrin);GO:0035754(B cell chemotaxis);GO:0035768(endothelial cell chemotaxis to fibroblast growth factor);GO:0042742(defense response to bacterium);GO:0045765(regulation of angiogenesis);GO:0046982(protein heterodimerization activity);GO:0048018(receptor ligand activity);GO:0048248(CXCR3 chemokine receptor binding);GO:0060326(cell chemotaxis);GO:0061844(antimicrobial humoral immune response mediated by antimicrobial peptide);GO:0070098(chemokine-mediated signaling pathway);GO:0071222(cellular response to lipopolysaccharide);GO:0090630(activation of GTPase activity);GO:2000545(negative regulation of endothelial cell chemotaxis to fibroblast growth factor)","04060(Cytokine-cytokine receptor interaction);04062(Chemokine signaling pathway)","K10032","NA","C-X-C motif chemokine ligand 13 [Source:HGNC Symbol;Acc:HGNC:10639]",{"v":5.667334,"d":"5.67"},{"v":7.111124,"d":"7.11"},{"v":6.581259,"d":"6.58"},{"v":0.162677,"d":"0.16"},{"v":0.194052,"d":"0.19"},{"v":0.254038,"d":"0.25"},{"v":31.6973854186621,"d":"31.70"},{"v":4.98629193843514,"d":"4.99"},{"v":1.15015739769266e-5,"d":"0.00"},{"v":0.002221225185338,"d":"0.00"},"up","yes"]
[90416,0,"chr17","-",75751594,75765236,"ENST00000225614",9,1445,"ENSG00000108479","GALK1","GO:0000166(nucleotide binding);GO:0004335(galactokinase activity);GO:0005524(ATP binding);GO:0005534(galactose binding);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005975(carbohydrate metabolic process);GO:0006012(galactose metabolic process);GO:0016020(membrane);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0016740(transferase activity);GO:0016773(phosphotransferase activity, alcohol group as acceptor);GO:0019388(galactose catabolic process);GO:0019402(galactitol metabolic process);GO:0033499(galactose catabolic process via UDP-galactose);GO:0046835(carbohydrate phosphorylation);GO:0061623(glycolytic process from galactose);GO:0070062(extracellular exosome)","00052(Galactose metabolism);00520(Amino sugar and nucleotide sugar metabolism)","NA","NA","galactokinase 1 [Source:HGNC Symbol;Acc:HGNC:4118]",0,0,0,{"v":6.78008,"d":"6.78"},0,{"v":6.524437,"d":"6.52"},"-inf","-inf",{"v":1.15390578312851e-5,"d":"0.00"},{"v":0.002221225185338,"d":"0.00"},"down","yes"]
[118740,0,"chr2","+",165294031,165392310,"ENST00000283256",27,8660,"ENSG00000136531","SCN2A","GO:0001518(voltage-gated sodium channel complex);GO:0005216(ion channel activity);GO:0005244(voltage-gated ion channel activity);GO:0005248(voltage-gated sodium channel activity);GO:0005272(sodium channel activity);GO:0005515(protein binding);GO:0005886(plasma membrane);GO:0005887(integral component of plasma membrane);GO:0006811(ion transport);GO:0006814(sodium ion transport);GO:0007399(nervous system development);GO:0007613(memory);GO:0008627(intrinsic apoptotic signaling pathway in response to osmotic stress);GO:0014704(intercalated disc);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0019228(neuronal action potential);GO:0030315(T-tubule);GO:0030424(axon);GO:0031226(intrinsic component of plasma membrane);GO:0033268(node of Ranvier);GO:0033270(paranode region of axon);GO:0034220(ion transmembrane transport);GO:0034706(sodium channel complex);GO:0034765(regulation of ion transmembrane transport);GO:0035725(sodium ion transmembrane transport);GO:0042552(myelination);GO:0051402(neuron apoptotic process);GO:0055085(transmembrane transport);GO:0071456(cellular response to hypoxia);GO:0086010(membrane depolarization during action potential);GO:0098978(glutamatergic synapse);GO:0099056(integral component of presynaptic membrane)","04742(Taste transduction)","K04834","NA","sodium voltage-gated channel alpha subunit 2 [Source:HGNC Symbol;Acc:HGNC:10588]",0,0,0,{"v":1.160373,"d":"1.16"},0,{"v":1.072039,"d":"1.07"},"-inf","-inf",{"v":1.1555506744533e-5,"d":"0.00"},{"v":0.002221225185338,"d":"0.00"},"down","yes"]
[76376,0,"chr16","-",67438321,67481079,"ENST00000565835",6,905,"ENSG00000159720","ATP6V0D1","GO:0005515(protein binding);GO:0005765(lysosomal membrane);GO:0005769(early endosome);GO:0005813(centrosome);GO:0006811(ion transport);GO:0006879(cellular iron ion homeostasis);GO:0007034(vacuolar transport);GO:0007035(vacuolar acidification);GO:0007420(brain development);GO:0008021(synaptic vesicle);GO:0008286(insulin receptor signaling pathway);GO:0008553(proton-exporting ATPase activity, phosphorylative mechanism);GO:0010008(endosome membrane);GO:0015078(proton transmembrane transporter activity);GO:0015991(ATP hydrolysis coupled proton transport);GO:0016020(membrane);GO:0016241(regulation of macroautophagy);GO:0016324(apical plasma membrane);GO:0016471(vacuolar proton-transporting V-type ATPase complex);GO:0030030(cell projection organization);GO:0030670(phagocytic vesicle membrane);GO:0032991(protein-containing complex);GO:0033179(proton-transporting V-type ATPase, V0 domain);GO:0033181(plasma membrane proton-transporting V-type ATPase complex);GO:0033572(transferrin transport);GO:0034220(ion transmembrane transport);GO:0036295(cellular response to increased oxygen levels);GO:0036498(IRE1-mediated unfolded protein response);GO:0043005(neuron projection);GO:0043679(axon terminus);GO:0044877(protein-containing complex binding);GO:0046961(proton-transporting ATPase activity, rotational mechanism);GO:0060271(cilium assembly);GO:0070062(extracellular exosome);GO:0090383(phagosome acidification);GO:1902600(proton transmembrane transport)","00190(Oxidative phosphorylation);04142(Lysosome);04145(Phagosome);04721(Synaptic vesicle cycle);04966(Collecting duct acid secretion);05110(Vibrio cholerae infection);05120(Epithelial cell signaling in Helicobacter pylori infection);05152(Tuberculosis);05165(Human papillomavirus infection);05203(Viral carcinogenesis);05323(Rheumatoid arthritis)","NA","NA","ATPase H+ transporting V0 subunit d1 [Source:HGNC Symbol;Acc:HGNC:13724]",0,0,0,{"v":18.762104,"d":"18.76"},0,{"v":5.3788,"d":"5.38"},"-inf","-inf",{"v":1.19056225270635e-5,"d":"0.00"},{"v":0.00227648034951693,"d":"0.00"},"down","yes"]
[10064,0,"chr1","+",119711934,119744212,"ENST00000369409",12,1882,"ENSG00000092621","PHGDH","GO:0004617(phosphoglycerate dehydrogenase activity);GO:0005829(cytosol);GO:0006520(cellular amino acid metabolic process);GO:0006541(glutamine metabolic process);GO:0006544(glycine metabolic process);GO:0006563(L-serine metabolic process);GO:0006564(L-serine biosynthetic process);GO:0006566(threonine metabolic process);GO:0007420(brain development);GO:0008652(cellular amino acid biosynthetic process);GO:0009055(electron transfer activity);GO:0009448(gamma-aminobutyric acid metabolic process);GO:0010468(regulation of gene expression);GO:0016491(oxidoreductase activity);GO:0016616(oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor);GO:0019530(taurine metabolic process);GO:0021510(spinal cord development);GO:0021782(glial cell development);GO:0021915(neural tube development);GO:0022008(neurogenesis);GO:0022900(electron transport chain);GO:0030060(L-malate dehydrogenase activity);GO:0031175(neuron projection development);GO:0051287(NAD binding);GO:0055114(oxidation-reduction process);GO:0070062(extracellular exosome);GO:0070314(G1 to G0 transition)","00260(Glycine, serine and threonine metabolism)","K00058","1.1.1.399;EC:1.1.1.95","phosphoglycerate dehydrogenase [Source:HGNC Symbol;Acc:HGNC:8923]",{"v":11.454703,"d":"11.45"},{"v":2.301812,"d":"2.30"},0,0,0,0,"inf","inf",{"v":1.20723074197234e-5,"d":"0.00"},{"v":0.00229626664166781,"d":"0.00"},"up","yes"]
[68784,0,"chr15","+",99565990,99716406,"ENST00000449277",9,5182,"ENSG00000068305","MEF2A","GO:0000002(mitochondrial genome maintenance);GO:0000122(negative regulation of transcription by RNA polymerase II);GO:0000165(MAPK cascade);GO:0000790(nuclear chromatin);GO:0000977(RNA polymerase II regulatory region sequence-specific DNA binding);GO:0000978(RNA polymerase II proximal promoter sequence-specific DNA binding);GO:0000981(DNA-binding transcription factor activity, RNA polymerase II-specific);GO:0001085(RNA polymerase II transcription factor binding);GO:0001228(DNA-binding transcription activator activity, RNA polymerase II-specific);GO:0003677(DNA binding);GO:0003682(chromatin binding);GO:0003700(DNA-binding transcription factor activity);GO:0003713(transcription coactivator activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005667(transcription factor complex);GO:0005829(cytosol);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0006915(apoptotic process);GO:0007275(multicellular organism development);GO:0007399(nervous system development);GO:0007507(heart development);GO:0007517(muscle organ development);GO:0010613(positive regulation of cardiac muscle hypertrophy);GO:0019901(protein kinase binding);GO:0030154(cell differentiation);GO:0033613(activating transcription factor binding);GO:0035035(histone acetyltransferase binding);GO:0042826(histone deacetylase binding);GO:0043565(sequence-specific DNA binding);GO:0045893(positive regulation of transcription, DNA-templated);GO:0045944(positive regulation of transcription by RNA polymerase II);GO:0046326(positive regulation of glucose import);GO:0046332(SMAD binding);GO:0046982(protein heterodimerization activity);GO:0046983(protein dimerization activity);GO:0048311(mitochondrion distribution);GO:0048813(dendrite morphogenesis);GO:0051149(positive regulation of muscle cell differentiation);GO:0055005(ventricular cardiac myofibril assembly);GO:0061337(cardiac conduction);GO:0070375(ERK5 cascade);GO:0071277(cellular response to calcium ion)","04022(cGMP-PKG signaling pathway);04371(Apelin signaling pathway);04928(Parathyroid hormone synthesis, secretion and action);05418(Fluid shear stress and atherosclerosis)","K09260","NA","myocyte enhancer factor 2A [Source:HGNC Symbol;Acc:HGNC:6993]",0,0,0,{"v":1.747506,"d":"1.75"},0,{"v":1.841574,"d":"1.84"},"-inf","-inf",{"v":1.22562990463754e-5,"d":"0.00"},{"v":0.00231912158518134,"d":"0.00"},"down","yes"]
[68718,0,"chr15","+",99098217,99135593,"ENST00000560674",5,5908,"ENSG00000182253","SYNM","GO:0005198(structural molecule activity);GO:0005200(structural constituent of cytoskeleton);GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0005856(cytoskeleton);GO:0005882(intermediate filament);GO:0005912(adherens junction);GO:0008307(structural constituent of muscle);GO:0016020(membrane);GO:0017166(vinculin binding);GO:0019215(intermediate filament binding);GO:0030054(cell junction);GO:0031443(fast-twitch skeletal muscle fiber contraction);GO:0042383(sarcolemma);GO:0043034(costamere);GO:0045104(intermediate filament cytoskeleton organization);GO:0060053(neurofilament cytoskeleton)","NA","K10376","NA","synemin [Source:HGNC Symbol;Acc:HGNC:24466]",{"v":9.8e-5,"d":"0.00"},{"v":1.514947,"d":"1.51"},{"v":2.010051,"d":"2.01"},{"v":9.8e-5,"d":"0.00"},{"v":0.000118,"d":"0.00"},{"v":0.000423,"d":"0.00"},{"v":5516.58215962441,"d":"5516.58"},{"v":12.4295589957717,"d":"12.43"},{"v":1.25346793223661e-5,"d":"0.00"},{"v":0.00235162503073243,"d":"0.00"},"up","yes"]
[154425,0,"chr4","-",119296419,119304445,"ENST00000399075",3,2960,"ENSG00000164096","C4orf3","GO:0016020(membrane);GO:0016021(integral component of membrane)","NA","NA","NA","chromosome 4 open reading frame 3 [Source:HGNC Symbol;Acc:HGNC:19225]",{"v":0.014417,"d":"0.01"},{"v":0.019771,"d":"0.02"},{"v":0.023617,"d":"0.02"},{"v":4.513307,"d":"4.51"},{"v":4.7817,"d":"4.78"},{"v":0.027995,"d":"0.03"},{"v":0.00620025609776765,"d":"0.01"},{"v":-7.33345647829985,"d":"-7.33"},{"v":1.25575352590722e-5,"d":"0.00"},{"v":0.00235162503073243,"d":"0.00"},"down","yes"]
[143446,0,"chr3","+",122384176,122409917,"ENST00000232125",6,801,"ENSG00000114023","FAM162A","GO:0005515(protein binding);GO:0005739(mitochondrion);GO:0005829(cytosol);GO:0006915(apoptotic process);GO:0006919(activation of cysteine-type endopeptidase activity involved in apoptotic process);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0043065(positive regulation of apoptotic process);GO:0051402(neuron apoptotic process);GO:0071456(cellular response to hypoxia);GO:0090200(positive regulation of release of cytochrome c from mitochondria)","NA","NA","NA","family with sequence similarity 162 member A [Source:HGNC Symbol;Acc:HGNC:17865]",{"v":0.148364,"d":"0.15"},{"v":0.279133,"d":"0.28"},{"v":0.651228,"d":"0.65"},{"v":15.361239,"d":"15.36"},{"v":17.016966,"d":"17.02"},{"v":6.531844,"d":"6.53"},{"v":0.0277235579939773,"d":"0.03"},{"v":-5.17274376740545,"d":"-5.17"},{"v":1.37185444622771e-5,"d":"0.00"},{"v":0.00255587036058731,"d":"0.00"},"down","yes"]
[67601,0,"chr15","+",83447341,83618743,"ENST00000427482",9,1693,"ENSG00000140600","SH3GL3","GO:0001669(acrosomal vesicle);GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0005768(endosome);GO:0005769(early endosome);GO:0006897(endocytosis);GO:0007165(signal transduction);GO:0007417(central nervous system development);GO:0008022(protein C-terminus binding);GO:0008289(lipid binding);GO:0016020(membrane);GO:0031901(early endosome membrane);GO:0042802(identical protein binding);GO:0045202(synapse);GO:0045666(positive regulation of neuron differentiation);GO:0098793(presynapse);GO:0098845(postsynaptic endosome);GO:0098978(glutamatergic synapse);GO:0099092(postsynaptic density, intracellular component);GO:1900186(negative regulation of clathrin-dependent endocytosis);GO:2000369(regulation of clathrin-dependent endocytosis)","04144(Endocytosis)","NA","NA","SH3 domain containing GRB2 like 3, endophilin A3 [Source:HGNC Symbol;Acc:HGNC:10832]",{"v":0.677407,"d":"0.68"},{"v":0.369867,"d":"0.37"},{"v":0.984691,"d":"0.98"},0,0,0,"inf","inf",{"v":1.38614711779921e-5,"d":"0.00"},{"v":0.00256932269334925,"d":"0.00"},"up","yes"]
[11533,0,"chr1","+",153634080,153646302,"ENST00000403433",5,1923,"ENSG00000160679","CHTOP","GO:0000346(transcription export complex);GO:0003723(RNA binding);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005730(nucleolus);GO:0006405(RNA export from nucleus);GO:0006406(mRNA export from nucleus);GO:0008284(positive regulation of cell population proliferation);GO:0008327(methyl-CpG binding);GO:0016607(nuclear speck);GO:0031062(positive regulation of histone methylation);GO:0031124(mRNA 3'-end processing);GO:0032781(positive regulation of ATPase activity);GO:0036464(cytoplasmic ribonucleoprotein granule);GO:0051028(mRNA transport);GO:0051096(positive regulation of helicase activity)","NA","NA","NA","chromatin target of PRMT1 [Source:HGNC Symbol;Acc:HGNC:24511]",{"v":5.758362,"d":"5.76"},0,{"v":4.250396,"d":"4.25"},0,0,0,"inf","inf",{"v":1.39477905065593e-5,"d":"0.00"},{"v":0.00257219913250406,"d":"0.00"},"up","yes"]
[49171,0,"chr12","-",122272043,122422632,"ENST00000537178",24,5229,"ENSG00000130779","CLIP1","GO:0000278(mitotic cell cycle);GO:0000776(kinetochore);GO:0001578(microtubule bundle formation);GO:0001726(ruffle);GO:0005515(protein binding);GO:0005635(nuclear envelope);GO:0005737(cytoplasm);GO:0005768(endosome);GO:0005813(centrosome);GO:0005829(cytosol);GO:0005856(cytoskeleton);GO:0005874(microtubule);GO:0005881(cytoplasmic microtubule);GO:0005882(intermediate filament);GO:0008017(microtubule binding);GO:0008270(zinc ion binding);GO:0015630(microtubule cytoskeleton);GO:0015631(tubulin binding);GO:0016020(membrane);GO:0030659(cytoplasmic vesicle membrane);GO:0031116(positive regulation of microtubule polymerization);GO:0031410(cytoplasmic vesicle);GO:0035371(microtubule plus-end);GO:0042803(protein homodimerization activity);GO:0042995(cell projection);GO:0044354(macropinosome);GO:0044861(protein transport into plasma membrane raft);GO:0046872(metal ion binding);GO:0051010(microtubule plus-end binding)","04150(mTOR signaling pathway)","K10421","NA","CAP-Gly domain containing linker protein 1 [Source:HGNC Symbol;Acc:HGNC:10461]",{"v":0.458828,"d":"0.46"},{"v":0.833668,"d":"0.83"},{"v":1.534515,"d":"1.53"},{"v":10.680222,"d":"10.68"},{"v":9.93202,"d":"9.93"},{"v":10.774562,"d":"10.77"},{"v":0.0900700498209375,"d":"0.09"},{"v":-3.4728087303281,"d":"-3.47"},{"v":1.43008182561428e-5,"d":"0.00"},{"v":0.00262398347093771,"d":"0.00"},"down","yes"]
[162198,0,"chr5","-",126544154,126595219,"ENST00000636743",16,2332,"ENSG00000164904","ALDH7A1","GO:0004029(aldehyde dehydrogenase (NAD) activity);GO:0004043(L-aminoadipate-semialdehyde dehydrogenase activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005739(mitochondrion);GO:0005759(mitochondrial matrix);GO:0005829(cytosol);GO:0006081(cellular aldehyde metabolic process);GO:0006554(lysine catabolic process);GO:0007605(sensory perception of sound);GO:0008802(betaine-aldehyde dehydrogenase activity);GO:0016491(oxidoreductase activity);GO:0016620(oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor);GO:0019285(glycine betaine biosynthetic process from choline);GO:0042426(choline catabolic process);GO:0043878(glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity);GO:0055114(oxidation-reduction process);GO:0070062(extracellular exosome)","00010(Glycolysis / Gluconeogenesis);00053(Ascorbate and aldarate metabolism);00071(Fatty acid degradation);00260(Glycine, serine and threonine metabolism);00280(Valine, leucine and isoleucine degradation);00310(Lysine degradation);00330(Arginine and proline metabolism);00340(Histidine metabolism);00380(Tryptophan metabolism);00410(beta-Alanine metabolism);00561(Glycerolipid metabolism);00620(Pyruvate metabolism)","NA","NA","aldehyde dehydrogenase 7 family member A1 [Source:HGNC Symbol;Acc:HGNC:877]",0,{"v":4.269134,"d":"4.27"},{"v":3.779775,"d":"3.78"},0,0,0,"inf","inf",{"v":1.46313477509831e-5,"d":"0.00"},{"v":0.00267114001906139,"d":"0.00"},"up","yes"]
[71795,0,"chr16","+",14975123,15037687,"ENST00000569715",22,3775,"ENSG00000179889","PDXDC1","GO:0001667(ameboidal-type cell migration);GO:0003824(catalytic activity);GO:0005783(endoplasmic reticulum);GO:0005794(Golgi apparatus);GO:0006665(sphingolipid metabolic process);GO:0008117(sphinganine-1-phosphate aldolase activity);GO:0016829(lyase activity);GO:0016831(carboxy-lyase activity);GO:0019752(carboxylic acid metabolic process);GO:0030149(sphingolipid catabolic process);GO:0030170(pyridoxal phosphate binding);GO:0043231(intracellular membrane-bounded organelle);GO:0045296(cadherin binding)","NA","NA","NA","pyridoxal dependent decarboxylase domain containing 1 [Source:HGNC Symbol;Acc:HGNC:28995]",0,0,0,{"v":0.401843,"d":"0.40"},{"v":9.576328,"d":"9.58"},0,"-inf","-inf",{"v":1.48334701507385e-5,"d":"0.00"},{"v":0.00269449985288165,"d":"0.00"},"down","yes"]
[53170,0,"chr13","-",102784284,102798914,"ENST00000460338",9,2083,"ENSG00000134901","KDELC1","GO:0005515(protein binding);GO:0005783(endoplasmic reticulum);GO:0005788(endoplasmic reticulum lumen);GO:0006486(protein glycosylation);GO:0016740(transferase activity);GO:0016757(transferase activity, transferring glycosyl groups);GO:0018242(protein O-linked glycosylation via serine);GO:0030158(protein xylosyltransferase activity);GO:0035251(UDP-glucosyltransferase activity);GO:0035252(UDP-xylosyltransferase activity);GO:0046527(glucosyltransferase activity)","NA","NA","NA","KDEL motif containing 1 [Source:HGNC Symbol;Acc:HGNC:19350]",{"v":6.509711,"d":"6.51"},{"v":8.532353,"d":"8.53"},{"v":7.45651,"d":"7.46"},{"v":0.129774,"d":"0.13"},0,0,{"v":173.367346309738,"d":"173.37"},{"v":7.43768838272177,"d":"7.44"},{"v":1.52728205127955e-5,"d":"0.00"},{"v":0.00276050531955155,"d":"0.00"},"up","yes"]
[172898,0,"chr6","-",108041472,108044238,"ENST00000492130",2,2465,"ENSG00000081087","OSTM1","GO:0005764(lysosome);GO:0005765(lysosomal membrane);GO:0005829(cytosol);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0030316(osteoclast differentiation);GO:0034220(ion transmembrane transport)","NA","NA","NA","osteoclastogenesis associated transmembrane protein 1 [Source:HGNC Symbol;Acc:HGNC:21652]",0,0,0,{"v":2.50759,"d":"2.51"},0,{"v":4.148971,"d":"4.15"},"-inf","-inf",{"v":1.55232443924804e-5,"d":"0.00"},{"v":0.0027916156739852,"d":"0.00"},"down","yes"]
[153096,0,"chr4","-",87161043,87220525,"ENST00000425278",9,4049,"ENSG00000145332","KLHL8","GO:0005515(protein binding);GO:0005654(nucleoplasm);GO:0006511(ubiquitin-dependent protein catabolic process);GO:0016567(protein ubiquitination);GO:0031463(Cul3-RING ubiquitin ligase complex)","NA","K10446","NA","kelch like family member 8 [Source:HGNC Symbol;Acc:HGNC:18644]",{"v":1.881456,"d":"1.88"},0,{"v":2.589933,"d":"2.59"},0,0,0,"inf","inf",{"v":1.55986232265069e-5,"d":"0.00"},{"v":0.0027916156739852,"d":"0.00"},"up","yes"]
[118741,0,"chr2","+",165294037,165392310,"ENST00000636662",27,9456,"ENSG00000136531","SCN2A","GO:0001518(voltage-gated sodium channel complex);GO:0005216(ion channel activity);GO:0005244(voltage-gated ion channel activity);GO:0005248(voltage-gated sodium channel activity);GO:0005272(sodium channel activity);GO:0005515(protein binding);GO:0005886(plasma membrane);GO:0005887(integral component of plasma membrane);GO:0006811(ion transport);GO:0006814(sodium ion transport);GO:0007399(nervous system development);GO:0007613(memory);GO:0008627(intrinsic apoptotic signaling pathway in response to osmotic stress);GO:0014704(intercalated disc);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0019228(neuronal action potential);GO:0030315(T-tubule);GO:0030424(axon);GO:0031226(intrinsic component of plasma membrane);GO:0033268(node of Ranvier);GO:0033270(paranode region of axon);GO:0034220(ion transmembrane transport);GO:0034706(sodium channel complex);GO:0034765(regulation of ion transmembrane transport);GO:0035725(sodium ion transmembrane transport);GO:0042552(myelination);GO:0051402(neuron apoptotic process);GO:0055085(transmembrane transport);GO:0071456(cellular response to hypoxia);GO:0086010(membrane depolarization during action potential);GO:0098978(glutamatergic synapse);GO:0099056(integral component of presynaptic membrane)","04742(Taste transduction)","K04834","NA","sodium voltage-gated channel alpha subunit 2 [Source:HGNC Symbol;Acc:HGNC:10588]",{"v":0.12621,"d":"0.13"},{"v":0.022434,"d":"0.02"},{"v":0.311755,"d":"0.31"},0,0,0,"inf","inf",{"v":1.57719879009757e-5,"d":"0.00"},{"v":0.00280880549236494,"d":"0.00"},"up","yes"]
[1505,0,"chr1","+",11013728,11023234,"ENST00000649624",6,810,"ENSG00000120948","TARDBP","GO:0001228(DNA-binding transcription activator activity, RNA polymerase II-specific);GO:0001933(negative regulation of protein phosphorylation);GO:0003676(nucleic acid binding);GO:0003677(DNA binding);GO:0003690(double-stranded DNA binding);GO:0003700(DNA-binding transcription factor activity);GO:0003723(RNA binding);GO:0003727(single-stranded RNA binding);GO:0003730(mRNA 3'-UTR binding);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005726(perichromatin fibrils);GO:0005737(cytoplasm);GO:0006355(regulation of transcription, DNA-templated);GO:0006366(transcription by RNA polymerase II);GO:0006397(mRNA processing);GO:0008380(RNA splicing);GO:0010494(cytoplasmic stress granule);GO:0010629(negative regulation of gene expression);GO:0016607(nuclear speck);GO:0031647(regulation of protein stability);GO:0032024(positive regulation of insulin secretion);GO:0034976(response to endoplasmic reticulum stress);GO:0035061(interchromatin granule);GO:0042307(positive regulation of protein import into nucleus);GO:0042752(regulation of circadian rhythm);GO:0042802(identical protein binding);GO:0042981(regulation of apoptotic process);GO:0043922(negative regulation by host of viral transcription);GO:0045944(positive regulation of transcription by RNA polymerase II);GO:0051726(regulation of cell cycle);GO:0070935(3'-UTR-mediated mRNA stabilization);GO:0071765(nuclear inner membrane organization);GO:1990837(sequence-specific double-stranded DNA binding);GO:1990904(ribonucleoprotein complex)","NA","NA","NA","TAR DNA binding protein [Source:HGNC Symbol;Acc:HGNC:11571]",0,0,0,{"v":6.637331,"d":"6.64"},0,{"v":14.047318,"d":"14.05"},"-inf","-inf",{"v":1.61341835465268e-5,"d":"0.00"},{"v":0.00285929213778204,"d":"0.00"},"down","yes"]
[154421,0,"chr4","+",119239640,119294638,"ENST00000509769",16,4803,"ENSG00000145390","USP53","GO:0001508(action potential);GO:0005515(protein binding);GO:0005575(cellular_component);GO:0005911(cell-cell junction);GO:0005923(bicellular tight junction);GO:0006915(apoptotic process);GO:0007605(sensory perception of sound);GO:0008150(biological_process);GO:0010996(response to auditory stimulus);GO:0016579(protein deubiquitination);GO:0030054(cell junction);GO:0036459(thiol-dependent ubiquitinyl hydrolase activity);GO:0051402(neuron apoptotic process)","NA","NA","NA","ubiquitin specific peptidase 53 [Source:HGNC Symbol;Acc:HGNC:29255]",{"v":0.002108,"d":"0.00"},0,0,{"v":0.002106,"d":"0.00"},{"v":2.108215,"d":"2.11"},{"v":1.124154,"d":"1.12"},{"v":0.000651728642206231,"d":"0.00"},{"v":-10.5834409795608,"d":"-10.58"},{"v":1.68996192801483e-5,"d":"0.00"},{"v":0.00298040373032906,"d":"0.00"},"down","yes"]
[116481,0,"chr2","+",113117897,113134016,"ENST00000354115",5,1747,"ENSG00000136689","IL1RN","GO:0005125(cytokine activity);GO:0005149(interleukin-1 receptor binding);GO:0005150(interleukin-1, type I receptor binding);GO:0005151(interleukin-1, type II receptor binding);GO:0005152(interleukin-1 receptor antagonist activity);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0005615(extracellular space);GO:0005737(cytoplasm);GO:0005886(plasma membrane);GO:0006629(lipid metabolic process);GO:0006954(inflammatory response);GO:0006955(immune response);GO:0010469(regulation of signaling receptor activity);GO:0019221(cytokine-mediated signaling pathway);GO:0030073(insulin secretion);GO:0030593(neutrophil chemotaxis);GO:0031982(vesicle);GO:0032755(positive regulation of interleukin-6 production);GO:0034115(negative regulation of heterotypic cell-cell adhesion);GO:0043123(positive regulation of I-kappaB kinase/NF-kappaB signaling);GO:0045352(interleukin-1 type I receptor antagonist activity);GO:0045353(interleukin-1 type II receptor antagonist activity);GO:0046330(positive regulation of JNK cascade);GO:0051384(response to glucocorticoid);GO:0070062(extracellular exosome);GO:0070498(interleukin-1-mediated signaling pathway);GO:0071222(cellular response to lipopolysaccharide);GO:2000660(negative regulation of interleukin-1-mediated signaling pathway)","04060(Cytokine-cytokine receptor interaction)","K05481","NA","interleukin 1 receptor antagonist [Source:HGNC Symbol;Acc:HGNC:6000]",{"v":0.452443,"d":"0.45"},{"v":0.503766,"d":"0.50"},{"v":0.870269,"d":"0.87"},0,0,0,"inf","inf",{"v":1.69931523964206e-5,"d":"0.00"},{"v":0.00298242138435729,"d":"0.00"},"up","yes"]
[174962,0,"chr6","+",150866333,151101885,"ENST00000618312",28,3159,"ENSG00000120254","MTHFD1L","GO:0000166(nucleotide binding);GO:0001843(neural tube closure);GO:0004329(formate-tetrahydrofolate ligase activity);GO:0004488(methylenetetrahydrofolate dehydrogenase (NADP+) activity);GO:0005524(ATP binding);GO:0005737(cytoplasm);GO:0005739(mitochondrion);GO:0005759(mitochondrial matrix);GO:0006730(one-carbon metabolic process);GO:0006760(folic acid-containing compound metabolic process);GO:0009113(purine nucleobase biosynthetic process);GO:0009257(10-formyltetrahydrofolate biosynthetic process);GO:0015942(formate metabolic process);GO:0016020(membrane);GO:0016874(ligase activity);GO:0035999(tetrahydrofolate interconversion);GO:0042803(protein homodimerization activity);GO:0046655(folic acid metabolic process);GO:0048702(embryonic neurocranium morphogenesis);GO:0048703(embryonic viscerocranium morphogenesis);GO:0055114(oxidation-reduction process)","00670(One carbon pool by folate)","K13402","EC:6.3.4.3","methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like [Source:HGNC Symbol;Acc:HGNC:21055]",{"v":2.194991,"d":"2.19"},{"v":3.133934,"d":"3.13"},0,0,0,0,"inf","inf",{"v":1.71176997008268e-5,"d":"0.00"},{"v":0.0029898366833223,"d":"0.00"},"up","yes"]
[45957,0,"chr12","-",76351797,76559771,"ENST00000261183",24,7204,"ENSG00000091039","OSBPL8","GO:0001786(phosphatidylserine binding);GO:0005548(phospholipid transporter activity);GO:0005634(nucleus);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005829(cytosol);GO:0006869(lipid transport);GO:0008289(lipid binding);GO:0010891(negative regulation of sequestering of triglyceride);GO:0015248(sterol transporter activity);GO:0015485(cholesterol binding);GO:0015914(phospholipid transport);GO:0015918(sterol transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0030336(negative regulation of cell migration);GO:0031965(nuclear membrane);GO:0032148(activation of protein kinase B activity);GO:0032934(sterol binding);GO:0036150(phosphatidylserine acyl-chain remodeling);GO:0043231(intracellular membrane-bounded organelle);GO:0045444(fat cell differentiation);GO:0046326(positive regulation of glucose import);GO:0046628(positive regulation of insulin receptor signaling pathway);GO:0051897(positive regulation of protein kinase B signaling);GO:0070273(phosphatidylinositol-4-phosphate binding);GO:0090204(protein localization to nuclear pore)","NA","K22285","NA","oxysterol binding protein like 8 [Source:HGNC Symbol;Acc:HGNC:16396]",0,{"v":9.6e-5,"d":"0.00"},0,{"v":2.657193,"d":"2.66"},{"v":1.355134,"d":"1.36"},0,{"v":2.39262652321209e-5,"d":"0.00"},{"v":-15.3510452573183,"d":"-15.35"},{"v":1.73421643305583e-5,"d":"0.00"},{"v":0.00301454942645542,"d":"0.00"},"down","yes"]
[105016,0,"chr19","+",44662278,44672704,"ENST00000622237",4,835,"ENSG00000186567","CEACAM19","GO:0005515(protein binding);GO:0016020(membrane);GO:0016021(integral component of membrane)","NA","K16825","NA","carcinoembryonic antigen related cell adhesion molecule 19 [Source:HGNC Symbol;Acc:HGNC:31951]",0,0,0,{"v":1.185438,"d":"1.19"},{"v":1.323394,"d":"1.32"},{"v":1.112083,"d":"1.11"},"-inf","-inf",{"v":1.75761295011235e-5,"d":"0.00"},{"v":0.00304067040369436,"d":"0.00"},"down","yes"]
[4512,0,"chr1","-",37860697,37931749,"ENST00000373027",18,3905,"ENSG00000204084","INPP5B","GO:0001701(in utero embryonic development);GO:0004439(phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity);GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0005768(endosome);GO:0005793(endoplasmic reticulum-Golgi intermediate compartment);GO:0005794(Golgi apparatus);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0007165(signal transduction);GO:0007283(spermatogenesis);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016787(hydrolase activity);GO:0030317(flagellated sperm motility);GO:0030670(phagocytic vesicle membrane);GO:0031410(cytoplasmic vesicle);GO:0031901(early endosome membrane);GO:0043647(inositol phosphate metabolic process);GO:0046855(inositol phosphate dephosphorylation);GO:0046856(phosphatidylinositol dephosphorylation);GO:0046872(metal ion binding);GO:0051056(regulation of small GTPase mediated signal transduction);GO:0052658(inositol-1,4,5-trisphosphate 5-phosphatase activity);GO:0052745(inositol phosphate phosphatase activity);GO:0070613(regulation of protein processing)","00562(Inositol phosphate metabolism);04070(Phosphatidylinositol signaling system)","K01099","EC:3.1.3.36","inositol polyphosphate-5-phosphatase B [Source:HGNC Symbol;Acc:HGNC:6077]",{"v":3.38009,"d":"3.38"},0,{"v":1.306787,"d":"1.31"},0,0,0,"inf","inf",{"v":1.77478128957827e-5,"d":"0.00"},{"v":0.00305582010665302,"d":"0.00"},"up","yes"]
[9679,0,"chr1","-",113697205,113759338,"ENST00000369598",18,3000,"ENSG00000116793","PHTF1","GO:0003677(DNA binding);GO:0003700(DNA-binding transcription factor activity);GO:0005634(nucleus);GO:0005783(endoplasmic reticulum);GO:0005801(cis-Golgi network);GO:0006355(regulation of transcription, DNA-templated);GO:0016020(membrane);GO:0016021(integral component of membrane)","NA","NA","NA","putative homeodomain transcription factor 1 [Source:HGNC Symbol;Acc:HGNC:8939]",0,0,0,{"v":2.068676,"d":"2.07"},0,{"v":2.97392,"d":"2.97"},"-inf","-inf",{"v":1.79518872218578e-5,"d":"0.00"},{"v":0.00307637765457592,"d":"0.00"},"down","yes"]
[31651,0,"chr11","+",63681573,63759089,"ENST00000354497",4,1407,"ENSG00000133318","RTN3","GO:0000139(Golgi membrane);GO:0005515(protein binding);GO:0005615(extracellular space);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005794(Golgi apparatus);GO:0005886(plasma membrane);GO:0006915(apoptotic process);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016032(viral process);GO:0016192(vesicle-mediated transport);GO:0045202(synapse);GO:0071786(endoplasmic reticulum tubular network organization);GO:0071787(endoplasmic reticulum tubular network formation)","05010(Alzheimer disease)","K20723","NA","reticulon 3 [Source:HGNC Symbol;Acc:HGNC:10469]",0,0,0,{"v":5.727516,"d":"5.73"},0,{"v":4.528803,"d":"4.53"},"-inf","-inf",{"v":1.88747928136097e-5,"d":"0.00"},{"v":0.00321934846440582,"d":"0.00"},"down","yes"]
[202465,0,"chrX","+",41334162,41349867,"ENST00000645589",17,4239,"ENSG00000215301","DDX3X","GO:0000166(nucleotide binding);GO:0002376(immune system process);GO:0003676(nucleic acid binding);GO:0003677(DNA binding);GO:0003723(RNA binding);GO:0003924(GTPase activity);GO:0004003(ATP-dependent DNA helicase activity);GO:0004004(ATP-dependent RNA helicase activity);GO:0004386(helicase activity);GO:0005515(protein binding);GO:0005524(ATP binding);GO:0005576(extracellular region);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005739(mitochondrion);GO:0005741(mitochondrial outer membrane);GO:0005829(cytosol);GO:0005852(eukaryotic translation initiation factor 3 complex);GO:0006413(translational initiation);GO:0006417(regulation of translation);GO:0006915(apoptotic process);GO:0007059(chromosome segregation);GO:0008134(transcription factor binding);GO:0008143(poly(A) binding);GO:0008190(eukaryotic initiation factor 4E binding);GO:0008625(extrinsic apoptotic signaling pathway via death domain receptors);GO:0009615(response to virus);GO:0010494(cytoplasmic stress granule);GO:0010501(RNA secondary structure unwinding);GO:0010628(positive regulation of gene expression);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016032(viral process);GO:0016055(Wnt signaling pathway);GO:0016607(nuclear speck);GO:0016787(hydrolase activity);GO:0016887(ATPase activity);GO:0017111(nucleoside-triphosphatase activity);GO:0017148(negative regulation of translation);GO:0022627(cytosolic small ribosomal subunit);GO:0030307(positive regulation of cell growth);GO:0030308(negative regulation of cell growth);GO:0031333(negative regulation of protein complex assembly);GO:0031369(translation initiation factor binding);GO:0032508(DNA duplex unwinding);GO:0032728(positive regulation of interferon-beta production);GO:0033592(RNA strand annealing activity);GO:0034063(stress granule assembly);GO:0034774(secretory granule lumen);GO:0035556(intracellular signal transduction);GO:0035613(RNA stem-loop binding);GO:0042254(ribosome biogenesis);GO:0042256(mature ribosome assembly);GO:0043024(ribosomal small subunit binding);GO:0043065(positive regulation of apoptotic process);GO:0043066(negative regulation of apoptotic process);GO:0043154(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process);GO:0043273(CTPase activity);GO:0043280(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process);GO:0043312(neutrophil degranulation);GO:0043539(protein serine/threonine kinase activator activity);GO:0045070(positive regulation of viral genome replication);GO:0045087(innate immune response);GO:0045296(cadherin binding);GO:0045727(positive regulation of translation);GO:0045944(positive regulation of transcription by RNA polymerase II);GO:0045948(positive regulation of translational initiation);GO:0048027(mRNA 5'-UTR binding);GO:0070062(extracellular exosome);GO:0071243(cellular response to arsenic-containing substance);GO:0071470(cellular response to osmotic stress);GO:0071651(positive regulation of chemokine (C-C motif) ligand 5 production);GO:0071902(positive regulation of protein serine/threonine kinase activity);GO:0090263(positive regulation of canonical Wnt signaling pathway);GO:0097193(intrinsic apoptotic signaling pathway);GO:1900087(positive regulation of G1/S transition of mitotic cell cycle);GO:1903608(protein localization to cytoplasmic stress granule);GO:1904813(ficolin-1-rich granule lumen);GO:2001243(negative regulation of intrinsic apoptotic signaling pathway)","04622(RIG-I-like receptor signaling pathway);05161(Hepatitis B);05203(Viral carcinogenesis)","K11594","EC:3.6.4.13","DEAD-box helicase 3 X-linked [Source:HGNC Symbol;Acc:HGNC:2745]",0,{"v":2.29852,"d":"2.30"},{"v":1.406043,"d":"1.41"},0,0,0,"inf","inf",{"v":2.01532693114929e-5,"d":"0.00"},{"v":0.00342134707517073,"d":"0.00"},"up","yes"]
[172792,0,"chr6","+",106098940,106109939,"ENST00000369089",5,4675,"ENSG00000057657","PRDM1","GO:0000122(negative regulation of transcription by RNA polymerase II);GO:0000977(RNA polymerase II regulatory region sequence-specific DNA binding);GO:0000978(RNA polymerase II proximal promoter sequence-specific DNA binding);GO:0000981(DNA-binding transcription factor activity, RNA polymerase II-specific);GO:0001227(DNA-binding transcription repressor activity, RNA polymerase II-specific);GO:0001701(in utero embryonic development);GO:0001763(morphogenesis of a branching structure);GO:0001892(embryonic placenta development);GO:0001893(maternal placenta development);GO:0002250(adaptive immune response);GO:0002376(immune system process);GO:0003170(heart valve development);GO:0003279(cardiac septum development);GO:0003281(ventricular septum development);GO:0003676(nucleic acid binding);GO:0003677(DNA binding);GO:0003700(DNA-binding transcription factor activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0007281(germ cell development);GO:0008168(methyltransferase activity);GO:0009791(post-embryonic development);GO:0010628(positive regulation of gene expression);GO:0010629(negative regulation of gene expression);GO:0016740(transferase activity);GO:0031490(chromatin DNA binding);GO:0032259(methylation);GO:0032823(regulation of natural killer cell differentiation);GO:0033082(regulation of extrathymic T cell differentiation);GO:0035904(aorta development);GO:0042127(regulation of cell population proliferation);GO:0042462(eye photoreceptor cell development);GO:0042826(histone deacetylase binding);GO:0043565(sequence-specific DNA binding);GO:0045087(innate immune response);GO:0045165(cell fate commitment);GO:0046872(metal ion binding);GO:0048844(artery morphogenesis);GO:0051136(regulation of NK T cell differentiation);GO:0060576(intestinal epithelial cell development);GO:0060707(trophoblast giant cell differentiation);GO:0060976(coronary vasculature development);GO:1990654(sebum secreting cell proliferation);GO:1990841(promoter-specific chromatin binding)","NA","NA","NA","PR/SET domain 1 [Source:HGNC Symbol;Acc:HGNC:9346]",{"v":3.012396,"d":"3.01"},{"v":0.861835,"d":"0.86"},0,0,0,0,"inf","inf",{"v":2.03166718610349e-5,"d":"0.00"},{"v":0.00343304506377395,"d":"0.00"},"up","yes"]
[48376,0,"chr12","-",113816738,113818179,"ENST00000553232",2,1265,"ENSG00000122965","RBM19","GO:0000381(regulation of alternative mRNA splicing, via spliceosome);GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005694(chromosome);GO:0005730(nucleolus);GO:0005737(cytoplasm);GO:0007275(multicellular organism development);GO:0016020(membrane);GO:0016607(nuclear speck);GO:0040019(positive regulation of embryonic development);GO:0045292(mRNA cis splicing, via spliceosome)","NA","K14787","NA","RNA binding motif protein 19 [Source:HGNC Symbol;Acc:HGNC:29098]",0,0,0,{"v":0.351098,"d":"0.35"},{"v":0.775001,"d":"0.78"},{"v":1.505734,"d":"1.51"},"-inf","-inf",{"v":2.06555066727708e-5,"d":"0.00"},{"v":0.0034741414695452,"d":"0.00"},"down","yes"]
[30345,0,"chr11","-",57299638,57324952,"ENST00000528882",7,4336,"ENSG00000149115","TNKS1BP1","GO:0000289(nuclear-transcribed mRNA poly(A) tail shortening);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005694(chromosome);GO:0005720(nuclear heterochromatin);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005856(cytoskeleton);GO:0005913(cell-cell adherens junction);GO:0006302(double-strand break repair);GO:0006977(DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest);GO:0007004(telomere maintenance via telomerase);GO:0010800(positive regulation of peptidyl-threonine phosphorylation);GO:0019899(enzyme binding);GO:0030014(CCR4-NOT complex);GO:0031954(positive regulation of protein autophosphorylation);GO:0033138(positive regulation of peptidyl-serine phosphorylation);GO:0044877(protein-containing complex binding);GO:0045296(cadherin binding);GO:0071479(cellular response to ionizing radiation);GO:0071532(ankyrin repeat binding)","NA","NA","NA","tankyrase 1 binding protein 1 [Source:HGNC Symbol;Acc:HGNC:19081]",{"v":0.019914,"d":"0.02"},0,{"v":0.003894,"d":"0.00"},{"v":2.935221,"d":"2.94"},{"v":2.322855,"d":"2.32"},{"v":0.048451,"d":"0.05"},{"v":0.00448655024274822,"d":"0.00"},{"v":-7.8001777173357,"d":"-7.80"},{"v":2.12434482063182e-5,"d":"0.00"},{"v":0.00354086695320296,"d":"0.00"},"down","yes"]
[71866,0,"chr16","-",15596171,15643108,"ENST00000548025",27,5891,"ENSG00000166783","MARF1","GO:0003674(molecular_function);GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0005777(peroxisome);GO:0005794(Golgi apparatus);GO:0006302(double-strand break repair);GO:0007143(female meiotic nuclear division);GO:0010468(regulation of gene expression);GO:0010923(negative regulation of phosphatase activity);GO:0016020(membrane);GO:0030154(cell differentiation);GO:0043231(intracellular membrane-bounded organelle);GO:0048477(oogenesis);GO:0051321(meiotic cell cycle)","NA","K17573","NA","meiosis regulator and mRNA stability factor 1 [Source:HGNC Symbol;Acc:HGNC:29562]",0,0,0,0,{"v":0.745729,"d":"0.75"},{"v":1.986261,"d":"1.99"},"-inf","-inf",{"v":2.12697015293302e-5,"d":"0.00"},{"v":0.00354086695320296,"d":"0.00"},"down","yes"]
[31740,0,"chr11","-",64223799,64226150,"ENST00000394547",7,865,"ENSG00000149743","TRPT1","GO:0000215(tRNA 2'-phosphotransferase activity);GO:0003674(molecular_function);GO:0006388(tRNA splicing, via endonucleolytic cleavage and ligation);GO:0008033(tRNA processing);GO:0008150(biological_process);GO:0016740(transferase activity);GO:0016772(transferase activity, transferring phosphorus-containing groups);GO:0045859(regulation of protein kinase activity)","NA","K10669","EC:2.7.1.160","tRNA phosphotransferase 1 [Source:HGNC Symbol;Acc:HGNC:20316]",0,0,0,{"v":0.000614,"d":"0.00"},{"v":3.397768,"d":"3.40"},{"v":4.0182,"d":"4.02"},"-inf","-inf",{"v":2.13446149945347e-5,"d":"0.00"},{"v":0.00354086695320296,"d":"0.00"},"down","yes"]
[199604,0,"chr9","+",128552593,128633662,"ENST00000358161",55,7794,"ENSG00000197694","SPTAN1","GO:0000165(MAPK cascade);GO:0003779(actin binding);GO:0005200(structural constituent of cytoskeleton);GO:0005509(calcium ion binding);GO:0005515(protein binding);GO:0005516(calmodulin binding);GO:0005576(extracellular region);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005856(cytoskeleton);GO:0005938(cell cortex);GO:0006888(endoplasmic reticulum to Golgi vesicle-mediated transport);GO:0007010(cytoskeleton organization);GO:0007411(axon guidance);GO:0008091(spectrin);GO:0015630(microtubule cytoskeleton);GO:0016020(membrane);GO:0035580(specific granule lumen);GO:0043231(intracellular membrane-bounded organelle);GO:0043312(neutrophil degranulation);GO:0045296(cadherin binding);GO:0046872(metal ion binding);GO:0051693(actin filament capping);GO:0070062(extracellular exosome);GO:1903561(extracellular vesicle);GO:1904724(tertiary granule lumen)","04210(Apoptosis)","K06114","NA","spectrin alpha, non-erythrocytic 1 [Source:HGNC Symbol;Acc:HGNC:11273]",0,0,0,{"v":0.95412,"d":"0.95"},{"v":0.844428,"d":"0.84"},0,"-inf","-inf",{"v":2.15710970082287e-5,"d":"0.00"},{"v":0.00354710629557216,"d":"0.00"},"down","yes"]
[29070,0,"chr11","+",35139170,35229468,"ENST00000415148",17,2369,"ENSG00000026508","CD44","GO:0004888(transmembrane signaling receptor activity);GO:0004896(cytokine receptor activity);GO:0005515(protein binding);GO:0005518(collagen binding);GO:0005540(hyaluronic acid binding);GO:0005794(Golgi apparatus);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0005887(integral component of plasma membrane);GO:0005902(microvillus);GO:0005925(focal adhesion);GO:0006954(inflammatory response);GO:0007155(cell adhesion);GO:0007160(cell-matrix adhesion);GO:0009986(cell surface);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016323(basolateral plasma membrane);GO:0016324(apical plasma membrane);GO:0016477(cell migration);GO:0022617(extracellular matrix disassembly);GO:0030198(extracellular matrix organization);GO:0030214(hyaluronan catabolic process);GO:0030667(secretory granule membrane);GO:0031258(lamellipodium membrane);GO:0033138(positive regulation of peptidyl-serine phosphorylation);GO:0033674(positive regulation of kinase activity);GO:0034116(positive regulation of heterotypic cell-cell adhesion);GO:0035692(macrophage migration inhibitory factor receptor complex);GO:0042110(T cell activation);GO:0042995(cell projection);GO:0043066(negative regulation of apoptotic process);GO:0043154(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process);GO:0043312(neutrophil degranulation);GO:0043518(negative regulation of DNA damage response, signal transduction by p53 class mediator);GO:0044319(wound healing, spreading of cells);GO:0044344(cellular response to fibroblast growth factor stimulus);GO:0050731(positive regulation of peptidyl-tyrosine phosphorylation);GO:0050900(leukocyte migration);GO:0051216(cartilage development);GO:0060333(interferon-gamma-mediated signaling pathway);GO:0070062(extracellular exosome);GO:0070374(positive regulation of ERK1 and ERK2 cascade);GO:0070487(monocyte aggregation);GO:0098609(cell-cell adhesion);GO:1900625(positive regulation of monocyte aggregation);GO:1902166(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator);GO:2000392(regulation of lamellipodium morphogenesis)","04512(ECM-receptor interaction);04640(Hematopoietic cell lineage);05131(Shigellosis);05169(Epstein-Barr virus infection);05205(Proteoglycans in cancer);05206(MicroRNAs in cancer)","NA","NA","CD44 molecule (Indian blood group) [Source:HGNC Symbol;Acc:HGNC:1681]",{"v":2.012126,"d":"2.01"},{"v":4.645655,"d":"4.65"},0,0,0,0,"inf","inf",{"v":2.15774976967093e-5,"d":"0.00"},{"v":0.00354710629557216,"d":"0.00"},"up","yes"]
[120865,0,"chr2","+",201116239,201154576,"ENST00000342795",9,1613,"ENSG00000003402","CFLAR","GO:0001666(response to hypoxia);GO:0002020(protease binding);GO:0004197(cysteine-type endopeptidase activity);GO:0005123(death receptor binding);GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0006508(proteolysis);GO:0006915(apoptotic process);GO:0007519(skeletal muscle tissue development);GO:0008047(enzyme activator activity);GO:0008234(cysteine-type peptidase activity);GO:0009617(response to bacterium);GO:0010667(negative regulation of cardiac muscle cell apoptotic process);GO:0010952(positive regulation of peptidase activity);GO:0010976(positive regulation of neuron projection development);GO:0014732(skeletal muscle atrophy);GO:0014842(regulation of skeletal muscle satellite cell proliferation);GO:0014866(skeletal myofibril assembly);GO:0016032(viral process);GO:0016504(peptidase activator activity);GO:0031264(death-inducing signaling complex);GO:0031265(CD95 death-inducing signaling complex);GO:0032869(cellular response to insulin stimulus);GO:0033574(response to testosterone);GO:0042981(regulation of apoptotic process);GO:0043066(negative regulation of apoptotic process);GO:0043085(positive regulation of catalytic activity);GO:0043123(positive regulation of I-kappaB kinase/NF-kappaB signaling);GO:0043154(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process);GO:0043403(skeletal muscle tissue regeneration);GO:0044877(protein-containing complex binding);GO:0045121(membrane raft);GO:0046982(protein heterodimerization activity);GO:0051092(positive regulation of NF-kappaB transcription factor activity);GO:0060544(regulation of necroptotic process);GO:0060546(negative regulation of necroptotic process);GO:0070374(positive regulation of ERK1 and ERK2 cascade);GO:0071364(cellular response to epidermal growth factor stimulus);GO:0071392(cellular response to estradiol stimulus);GO:0071456(cellular response to hypoxia);GO:0071549(cellular response to dexamethasone stimulus);GO:0071732(cellular response to nitric oxide);GO:0072126(positive regulation of glomerular mesangial cell proliferation);GO:0097153(cysteine-type endopeptidase activity involved in apoptotic process);GO:0097342(ripoptosome);GO:1901740(negative regulation of myoblast fusion);GO:1902041(regulation of extrinsic apoptotic signaling pathway via death domain receptors);GO:1902042(negative regulation of extrinsic apoptotic signaling pathway via death domain receptors);GO:1903055(positive regulation of extracellular matrix organization);GO:1903427(negative regulation of reactive oxygen species biosynthetic process);GO:1903845(negative regulation of cellular response to transforming growth factor beta stimulus);GO:1903944(negative regulation of hepatocyte apoptotic process);GO:1904036(negative regulation of epithelial cell apoptotic process);GO:2000347(positive regulation of hepatocyte proliferation);GO:2001237(negative regulation of extrinsic apoptotic signaling pathway)","04064(NF-kappa B signaling pathway);04140(Autophagy - animal);04210(Apoptosis);04217(Necroptosis);04668(TNF signaling pathway);05142(Chagas disease (American trypanosomiasis));05160(Hepatitis C)","K04724","NA","CASP8 and FADD like apoptosis regulator [Source:HGNC Symbol;Acc:HGNC:1876]",{"v":5.779823,"d":"5.78"},{"v":6.386002,"d":"6.39"},{"v":0.013629,"d":"0.01"},{"v":0.013034,"d":"0.01"},{"v":0.016081,"d":"0.02"},{"v":0.013453,"d":"0.01"},{"v":286.117600075174,"d":"286.12"},{"v":8.16046443528691,"d":"8.16"},{"v":2.20160723523901e-5,"d":"0.00"},{"v":0.00360228793591099,"d":"0.00"},"up","yes"]
[53893,0,"chr14","-",20311368,20333010,"ENST00000398160",7,1613,"ENSG00000100814","CCNB1IP1","GO:0000794(condensed nuclear chromosome);GO:0000795(synaptonemal complex);GO:0001825(blastocyst formation);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005694(chromosome);GO:0007131(reciprocal meiotic recombination);GO:0007286(spermatid development);GO:0016567(protein ubiquitination);GO:0016740(transferase activity);GO:0046872(metal ion binding);GO:0051026(chiasma assembly);GO:0051321(meiotic cell cycle)","NA","K10639","EC:2.3.2.27","cyclin B1 interacting protein 1 [Source:HGNC Symbol;Acc:HGNC:19437]",{"v":19.826946,"d":"19.83"},{"v":0.684884,"d":"0.68"},0,0,0,0,"inf","inf",{"v":2.2111483889572e-5,"d":"0.00"},{"v":0.00360228793591099,"d":"0.00"},"up","yes"]
[10508,0,"chr1","+",147242684,147295762,"ENST00000467213",21,2782,"ENSG00000131778","CHD1L","GO:0000166(nucleotide binding);GO:0000717(nucleotide-excision repair, DNA duplex unwinding);GO:0004003(ATP-dependent DNA helicase activity);GO:0004386(helicase activity);GO:0005515(protein binding);GO:0005524(ATP binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0006281(DNA repair);GO:0006293(nucleotide-excision repair, preincision complex stabilization);GO:0006294(nucleotide-excision repair, preincision complex assembly);GO:0006295(nucleotide-excision repair, DNA incision, 3'-to lesion);GO:0006296(nucleotide-excision repair, DNA incision, 5'-to lesion);GO:0006338(chromatin remodeling);GO:0006974(cellular response to DNA damage stimulus);GO:0016787(hydrolase activity);GO:0016887(ATPase activity);GO:0032508(DNA duplex unwinding);GO:0033683(nucleotide-excision repair, DNA incision);GO:0043044(ATP-dependent chromatin remodeling);GO:0070911(global genome nucleotide-excision repair)","NA","K20092","EC:3.6.4.12","chromodomain helicase DNA binding protein 1 like [Source:HGNC Symbol;Acc:HGNC:1916]",0,0,0,{"v":2.330203,"d":"2.33"},0,{"v":1.931527,"d":"1.93"},"-inf","-inf",{"v":2.24342201587315e-5,"d":"0.00"},{"v":0.00363855008199426,"d":"0.00"},"down","yes"]
[126491,0,"chr20","-",35739103,35742227,"ENST00000463098",4,869,"ENSG00000131051","RBM39","GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005815(microtubule organizing center);GO:0006396(RNA processing);GO:0006397(mRNA processing);GO:0008380(RNA splicing);GO:0015630(microtubule cytoskeleton);GO:0016607(nuclear speck);GO:0032991(protein-containing complex)","NA","K13091","NA","RNA binding motif protein 39 [Source:HGNC Symbol;Acc:HGNC:15923]",{"v":1.787422,"d":"1.79"},{"v":1.795558,"d":"1.80"},{"v":0.37507,"d":"0.38"},0,0,0,"inf","inf",{"v":2.27157525262787e-5,"d":"0.00"},{"v":0.00366783684124314,"d":"0.00"},"up","yes"]
[195775,0,"chr9","+",37120636,37358149,"ENST00000461038",9,2793,"ENSG00000147905","ZCCHC7","GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005730(nucleolus);GO:0005829(cytosol);GO:0008270(zinc ion binding);GO:0046872(metal ion binding)","03018(RNA degradation)","K12597","NA","zinc finger CCHC-type containing 7 [Source:HGNC Symbol;Acc:HGNC:26209]",0,0,0,0,{"v":4.199839,"d":"4.20"},{"v":1.418289,"d":"1.42"},"-inf","-inf",{"v":2.3454314858803e-5,"d":"0.00"},{"v":0.00375983938901097,"d":"0.00"},"down","yes"]
[71944,0,"chr16","+",16232601,16294806,"ENST00000263012",32,3911,"ENSG00000103226","NOMO3","GO:0003674(molecular_function);GO:0005575(cellular_component);GO:0005789(endoplasmic reticulum membrane);GO:0008150(biological_process);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0030246(carbohydrate binding)","NA","NA","NA","NODAL modulator 3 [Source:HGNC Symbol;Acc:HGNC:25242]",{"v":5.795136,"d":"5.80"},{"v":0.620518,"d":"0.62"},{"v":0.003667,"d":"0.00"},0,0,{"v":0.00469,"d":"0.00"},{"v":1368.72515991471,"d":"1368.73"},{"v":10.4186170670979,"d":"10.42"},{"v":2.34925279742772e-5,"d":"0.00"},{"v":0.00375983938901097,"d":"0.00"},"up","yes"]
[110937,0,"chr2","-",27650812,27663840,"ENST00000404798",5,4114,"ENSG00000119760","SUPT7L","GO:0003713(transcription coactivator activity);GO:0004402(histone acetyltransferase activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0030914(STAGA complex);GO:0043966(histone H3 acetylation);GO:0046982(protein heterodimerization activity);GO:0051457(maintenance of protein location in nucleus);GO:1903508(positive regulation of nucleic acid-templated transcription)","NA","K11316","NA","SPT7 like, STAGA complex gamma subunit [Source:HGNC Symbol;Acc:HGNC:30632]",{"v":0.235418,"d":"0.24"},{"v":0.30717,"d":"0.31"},{"v":0.985072,"d":"0.99"},{"v":0.001512,"d":"0.00"},{"v":0.001074,"d":"0.00"},{"v":0.012127,"d":"0.01"},{"v":103.830625977027,"d":"103.83"},{"v":6.69808823489894,"d":"6.70"},{"v":2.38890897358858e-5,"d":"0.00"},{"v":0.00380653785133654,"d":"0.00"},"up","yes"]
[36520,0,"chr11","+",114440671,114450261,"ENST00000546316",5,726,"ENSG00000076043","REXO2","GO:0000175(3'-5'-exoribonuclease activity);GO:0003676(nucleic acid binding);GO:0004518(nuclease activity);GO:0004527(exonuclease activity);GO:0005634(nucleus);GO:0005730(nucleolus);GO:0005737(cytoplasm);GO:0005739(mitochondrion);GO:0005758(mitochondrial intermembrane space);GO:0005759(mitochondrial matrix);GO:0005925(focal adhesion);GO:0006139(nucleobase-containing compound metabolic process);GO:0008408(3'-5' exonuclease activity);GO:0009117(nucleotide metabolic process);GO:0016787(hydrolase activity);GO:0090305(nucleic acid phosphodiester bond hydrolysis);GO:0090503(RNA phosphodiester bond hydrolysis, exonucleolytic)","03008(Ribosome biogenesis in eukaryotes)","K13288","EC:3.1.-.-","RNA exonuclease 2 [Source:HGNC Symbol;Acc:HGNC:17851]",0,0,0,{"v":6.590864,"d":"6.59"},0,{"v":8.696144,"d":"8.70"},"-inf","-inf",{"v":2.40058499998866e-5,"d":"0.00"},{"v":0.0038084389977986,"d":"0.00"},"down","yes"]
[205523,0,"chrX","+",111681267,111760256,"ENST00000623148",27,3689,"ENSG00000101901","ALG13","GO:0003723(RNA binding);GO:0003824(catalytic activity);GO:0004577(N-acetylglucosaminyldiphosphodolichol N-acetylglucosaminyltransferase activity);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0006488(dolichol-linked oligosaccharide biosynthetic process);GO:0006508(proteolysis);GO:0008152(metabolic process);GO:0008233(peptidase activity);GO:0008234(cysteine-type peptidase activity);GO:0016740(transferase activity);GO:0016757(transferase activity, transferring glycosyl groups);GO:0016758(transferase activity, transferring hexosyl groups);GO:0016787(hydrolase activity);GO:0036459(thiol-dependent ubiquitinyl hydrolase activity)","00510(N-Glycan biosynthesis)","K07432","EC:2.4.1.141","ALG13, UDP-N-acetylglucosaminyltransferase subunit [Source:HGNC Symbol;Acc:HGNC:30881]",{"v":1.052595,"d":"1.05"},0,{"v":3.155722,"d":"3.16"},0,0,0,"inf","inf",{"v":2.43097209298633e-5,"d":"0.00"},{"v":0.0038356406893516,"d":"0.00"},"up","yes"]
[104743,0,"chr19","-",43543312,43575563,"ENST00000543982",16,1994,"ENSG00000073050","XRCC1","GO:0000012(single strand break repair);GO:0000724(double-strand break repair via homologous recombination);GO:0000784(nuclear chromosome, telomeric region);GO:0000790(nuclear chromatin);GO:0001666(response to hypoxia);GO:0003684(damaged DNA binding);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005730(nucleolus);GO:0006281(DNA repair);GO:0006283(transcription-coupled nucleotide-excision repair);GO:0006284(base-excision repair);GO:0006288(base-excision repair, DNA ligation);GO:0006297(nucleotide-excision repair, DNA gap filling);GO:0006303(double-strand break repair via nonhomologous end joining);GO:0006974(cellular response to DNA damage stimulus);GO:0010033(response to organic substance);GO:0010836(negative regulation of protein ADP-ribosylation);GO:0019899(enzyme binding);GO:0021587(cerebellum morphogenesis);GO:0021766(hippocampus development);GO:0032356(oxidized DNA binding);GO:0033194(response to hydroperoxide);GO:0042493(response to drug);GO:0050882(voluntary musculoskeletal movement);GO:0061819(telomeric DNA-containing double minutes formation);GO:0070522(ERCC4-ERCC1 complex);GO:1903518(positive regulation of single strand break repair);GO:1904877(positive regulation of DNA ligase activity);GO:1905765(negative regulation of protection from non-homologous end joining at telomere);GO:1990414(replication-born double-strand break repair via sister chromatid exchange);GO:1990599(3' overhang single-stranded DNA endodeoxyribonuclease activity)","03410(Base excision repair)","K10803","NA","X-ray repair cross complementing 1 [Source:HGNC Symbol;Acc:HGNC:12828]",{"v":6.822504,"d":"6.82"},0,{"v":1.630446,"d":"1.63"},0,0,0,"inf","inf",{"v":2.43884668109061e-5,"d":"0.00"},{"v":0.0038356406893516,"d":"0.00"},"up","yes"]
[86720,0,"chr17","+",45894382,46028334,"ENST00000535772",11,5718,"ENSG00000186868","MAPT","GO:0000226(microtubule cytoskeleton organization);GO:0001774(microglial cell activation);GO:0003677(DNA binding);GO:0003680(AT DNA binding);GO:0003690(double-stranded DNA binding);GO:0003697(single-stranded DNA binding);GO:0003723(RNA binding);GO:0003779(actin binding);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0005623(cell);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005739(mitochondrion);GO:0005829(cytosol);GO:0005856(cytoskeleton);GO:0005874(microtubule);GO:0005886(plasma membrane);GO:0006475(internal protein amino acid acetylation);GO:0006919(activation of cysteine-type endopeptidase activity involved in apoptotic process);GO:0007267(cell-cell signaling);GO:0007613(memory);GO:0008017(microtubule binding);GO:0010288(response to lead ion);GO:0010469(regulation of signaling receptor activity);GO:0010506(regulation of autophagy);GO:0010629(negative regulation of gene expression);GO:0010917(negative regulation of mitochondrial membrane potential);GO:0015630(microtubule cytoskeleton);GO:0015631(tubulin binding);GO:0016020(membrane);GO:0016072(rRNA metabolic process);GO:0016607(nuclear speck);GO:0017124(SH3 domain binding);GO:0019896(axonal transport of mitochondrion);GO:0019899(enzyme binding);GO:0019901(protein kinase binding);GO:0021954(central nervous system neuron development);GO:0030424(axon);GO:0030425(dendrite);GO:0030426(growth cone);GO:0030673(axolemma);GO:0030674(protein binding, bridging);GO:0031110(regulation of microtubule polymerization or depolymerization);GO:0031113(regulation of microtubule polymerization);GO:0031116(positive regulation of microtubule polymerization);GO:0031122(cytoplasmic microtubule organization);GO:0031175(neuron projection development);GO:0032930(positive regulation of superoxide anion generation);GO:0033044(regulation of chromosome organization);GO:0033673(negative regulation of kinase activity);GO:0034063(stress granule assembly);GO:0034185(apolipoprotein binding);GO:0034399(nuclear periphery);GO:0034452(dynactin binding);GO:0034605(cellular response to heat);GO:0034614(cellular response to reactive oxygen species);GO:0035091(phosphatidylinositol binding);GO:0036464(cytoplasmic ribonucleoprotein granule);GO:0036477(somatodendritic compartment);GO:0042802(identical protein binding);GO:0042803(protein homodimerization activity);GO:0042995(cell projection);GO:0043005(neuron projection);GO:0043025(neuronal cell body);GO:0043197(dendritic spine);GO:0043565(sequence-specific DNA binding);GO:0044297(cell body);GO:0044304(main axon);GO:0045121(membrane raft);GO:0045298(tubulin complex);GO:0045773(positive regulation of axon extension);GO:0046785(microtubule polymerization);GO:0048018(receptor ligand activity);GO:0048143(astrocyte activation);GO:0048167(regulation of synaptic plasticity);GO:0048312(intracellular distribution of mitochondria);GO:0048699(generation of neurons);GO:0050808(synapse organization);GO:0050848(regulation of calcium-mediated signaling);GO:0051087(chaperone binding);GO:0051258(protein polymerization);GO:0051259(protein complex oligomerization);GO:0051721(protein phosphatase 2A binding);GO:0051879(Hsp90 protein binding);GO:0061564(axon development);GO:0070507(regulation of microtubule cytoskeleton organization);GO:0071813(lipoprotein particle binding);GO:0072386(plus-end-directed organelle transport along microtubule);GO:0090140(regulation of mitochondrial fission);GO:0090258(negative regulation of mitochondrial fission);GO:0097386(glial cell projection);GO:0097418(neurofibrillary tangle);GO:0097435(supramolecular fiber organization);GO:0098930(axonal transport);GO:0099077(histone-dependent DNA binding);GO:0099609(microtubule lateral binding);GO:1900034(regulation of cellular response to heat);GO:1900452(regulation of long-term synaptic depression);GO:1901216(positive regulation of neuron death);GO:1902474(positive regulation of protein localization to synapse);GO:1902936(phosphatidylinositol bisphosphate binding);GO:1902988(neurofibrillary tangle assembly);GO:1903748(negative regulation of establishment of protein localization to mitochondrion);GO:1903829(positive regulation of cellular protein localization);GO:1904115(axon cytoplasm);GO:1904428(negative regulation of tubulin deacetylation);GO:1905689(positive regulation of diacylglycerol kinase activity);GO:1990000(amyloid fibril formation);GO:1990090(cellular response to nerve growth factor stimulus);GO:1990416(cellular response to brain-derived neurotrophic factor stimulus);GO:2001020(regulation of response to DNA damage stimulus)","04010(MAPK signaling pathway);05010(Alzheimer disease)","K04380","NA","microtubule associated protein tau [Source:HGNC Symbol;Acc:HGNC:6893]",{"v":0.352372,"d":"0.35"},{"v":0.335625,"d":"0.34"},{"v":0.025071,"d":"0.03"},0,0,0,"inf","inf",{"v":2.45151332920079e-5,"d":"0.00"},{"v":0.00383894307111486,"d":"0.00"},"up","yes"]
[104128,0,"chr19","+",40778271,40808418,"ENST00000594136",12,2774,"ENSG00000171570","RAB4B-EGLN2","GO:0003924(GTPase activity);GO:0005525(GTP binding)","NA","NA","NA","RAB4B-EGLN2 readthrough (NMD candidate) [Source:HGNC Symbol;Acc:HGNC:44465]",0,0,0,{"v":1.672428,"d":"1.67"},0,{"v":2.24142,"d":"2.24"},"-inf","-inf",{"v":2.47603628446233e-5,"d":"0.00"},{"v":0.00384996838753073,"d":"0.00"},"down","yes"]
[12066,0,"chr1","-",155256007,155260450,"ENST00000472397",6,1030,"ENSG00000116521","SCAMP3","GO:0000139(Golgi membrane);GO:0005794(Golgi apparatus);GO:0006892(post-Golgi vesicle-mediated transport);GO:0015031(protein transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0031625(ubiquitin protein ligase binding);GO:0032588(trans-Golgi network membrane);GO:0043231(intracellular membrane-bounded organelle);GO:0055038(recycling endosome membrane);GO:0070062(extracellular exosome)","NA","K19995","NA","secretory carrier membrane protein 3 [Source:HGNC Symbol;Acc:HGNC:10565]",{"v":6.035862,"d":"6.04"},{"v":6.050891,"d":"6.05"},0,0,0,0,"inf","inf",{"v":2.48852821371546e-5,"d":"0.00"},{"v":0.00384996838753073,"d":"0.00"},"up","yes"]
[81183,0,"chr17","-",7913340,7915957,"ENST00000635932",1,2618,"ENSG00000179859","RNF227","GO:0046872(metal ion binding)","NA","NA","NA","ring finger protein 227 [Source:HGNC Symbol;Acc:HGNC:27571]",{"v":0.683043,"d":"0.68"},{"v":0.697325,"d":"0.70"},{"v":0.863477,"d":"0.86"},{"v":0.011123,"d":"0.01"},{"v":0.014996,"d":"0.01"},{"v":0.016253,"d":"0.02"},{"v":52.9558434815444,"d":"52.96"},{"v":5.72671798395292,"d":"5.73"},{"v":2.49034564015888e-5,"d":"0.00"},{"v":0.00384996838753073,"d":"0.00"},"up","yes"]
[34368,0,"chr11","+",75562056,75572783,"ENST00000533603",6,2299,"ENSG00000149257","SERPINH1","GO:0003433(chondrocyte development involved in endochondral bone morphogenesis);GO:0003723(RNA binding);GO:0004867(serine-type endopeptidase inhibitor activity);GO:0005518(collagen binding);GO:0005581(collagen trimer);GO:0005615(extracellular space);GO:0005737(cytoplasm);GO:0005783(endoplasmic reticulum);GO:0005788(endoplasmic reticulum lumen);GO:0005793(endoplasmic reticulum-Golgi intermediate compartment);GO:0006986(response to unfolded protein);GO:0010951(negative regulation of endopeptidase activity);GO:0030199(collagen fibril organization);GO:0032964(collagen biosynthetic process);GO:0045121(membrane raft);GO:0051082(unfolded protein binding);GO:0051604(protein maturation);GO:0062023(collagen-containing extracellular matrix)","NA","NA","NA","serpin family H member 1 [Source:HGNC Symbol;Acc:HGNC:1546]",{"v":1.749991,"d":"1.75"},0,{"v":4.279029,"d":"4.28"},0,0,0,"inf","inf",{"v":2.56317187513159e-5,"d":"0.00"},{"v":0.00394576416201402,"d":"0.00"},"up","yes"]
[103560,0,"chr19","-",38881100,38899678,"ENST00000420440",11,927,"ENSG00000068903","SIRT2","GO:0000122(negative regulation of transcription by RNA polymerase II);GO:0000183(chromatin silencing at rDNA);GO:0000781(chromosome, telomeric region);GO:0002376(immune system process);GO:0003682(chromatin binding);GO:0004407(histone deacetylase activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005677(chromatin silencing complex);GO:0005694(chromosome);GO:0005720(nuclear heterochromatin);GO:0005730(nucleolus);GO:0005737(cytoplasm);GO:0005739(mitochondrion);GO:0005813(centrosome);GO:0005814(centriole);GO:0005815(microtubule organizing center);GO:0005819(spindle);GO:0005829(cytosol);GO:0005856(cytoskeleton);GO:0005874(microtubule);GO:0005886(plasma membrane);GO:0006342(chromatin silencing);GO:0006348(chromatin silencing at telomere);GO:0006471(protein ADP-ribosylation);GO:0006476(protein deacetylation);GO:0006914(autophagy);GO:0007049(cell cycle);GO:0007096(regulation of exit from mitosis);GO:0007399(nervous system development);GO:0008134(transcription factor binding);GO:0008270(zinc ion binding);GO:0008285(negative regulation of cell population proliferation);GO:0010507(negative regulation of autophagy);GO:0010801(negative regulation of peptidyl-threonine phosphorylation);GO:0014065(phosphatidylinositol 3-kinase signaling);GO:0016020(membrane);GO:0016458(gene silencing);GO:0016575(histone deacetylation);GO:0016787(hydrolase activity);GO:0017136(NAD-dependent histone deacetylase activity);GO:0021762(substantia nigra development);GO:0022011(myelination in peripheral nervous system);GO:0030154(cell differentiation);GO:0030426(growth cone);GO:0030496(midbody);GO:0031641(regulation of myelination);GO:0032436(positive regulation of proteasomal ubiquitin-dependent protein catabolic process);GO:0033010(paranodal junction);GO:0033270(paranode region of axon);GO:0033558(protein deacetylase activity);GO:0034599(cellular response to oxidative stress);GO:0034979(NAD-dependent protein deacetylase activity);GO:0034983(peptidyl-lysine deacetylation);GO:0035035(histone acetyltransferase binding);GO:0035729(cellular response to hepatocyte growth factor stimulus);GO:0042177(negative regulation of protein catabolic process);GO:0042325(regulation of phosphorylation);GO:0042826(histone deacetylase binding);GO:0042903(tubulin deacetylase activity);GO:0042995(cell projection);GO:0043130(ubiquitin binding);GO:0043161(proteasome-mediated ubiquitin-dependent protein catabolic process);GO:0043204(perikaryon);GO:0043209(myelin sheath);GO:0043219(lateral loop);GO:0043220(Schmidt-Lanterman incisure);GO:0043388(positive regulation of DNA binding);GO:0043491(protein kinase B signaling);GO:0044224(juxtaparanode region of axon);GO:0044242(cellular lipid catabolic process);GO:0045087(innate immune response);GO:0045598(regulation of fat cell differentiation);GO:0045599(negative regulation of fat cell differentiation);GO:0045836(positive regulation of meiotic nuclear division);GO:0045843(negative regulation of striated muscle tissue development);GO:0045892(negative regulation of transcription, DNA-templated);GO:0045944(positive regulation of transcription by RNA polymerase II);GO:0046872(metal ion binding);GO:0046970(NAD-dependent histone deacetylase activity (H4-K16 specific));GO:0048012(hepatocyte growth factor receptor signaling pathway);GO:0048471(perinuclear region of cytoplasm);GO:0051301(cell division);GO:0051321(meiotic cell cycle);GO:0051726(regulation of cell cycle);GO:0051775(response to redox state);GO:0051781(positive regulation of cell division);GO:0051987(positive regulation of attachment of spindle microtubules to kinetochore);GO:0061428(negative regulation of transcription from RNA polymerase II promoter in response to hypoxia);GO:0061433(cellular response to caloric restriction);GO:0070403(NAD+ binding);GO:0070446(negative regulation of oligodendrocyte progenitor proliferation);GO:0070932(histone H3 deacetylation);GO:0070933(histone H4 deacetylation);GO:0071219(cellular response to molecule of bacterial origin);GO:0071456(cellular response to hypoxia);GO:0071872(cellular response to epinephrine stimulus);GO:0072686(mitotic spindle);GO:0072687(meiotic spindle);GO:0090042(tubulin deacetylation);GO:0097386(glial cell projection);GO:1900119(positive regulation of execution phase of apoptosis);GO:1900195(positive regulation of oocyte maturation);GO:1900226(negative regulation of NLRP3 inflammasome complex assembly);GO:1900425(negative regulation of defense response to bacterium);GO:2000378(negative regulation of reactive oxygen species metabolic process);GO:2000777(positive regulation of proteasomal ubiquitin-dependent protein catabolic process involved in cellular response to hypoxia)","NA","K11412","EC:3.5.1.-","sirtuin 2 [Source:HGNC Symbol;Acc:HGNC:10886]",0,0,0,{"v":1.101101,"d":"1.10"},{"v":0.771688,"d":"0.77"},{"v":1.087346,"d":"1.09"},"-inf","-inf",{"v":2.58311325279654e-5,"d":"0.00"},{"v":0.00395968373308432,"d":"0.00"},"down","yes"]
[91381,0,"chr17","+",80220469,80252716,"ENST00000572725",17,1862,"ENSG00000181045","SLC26A11","GO:0005654(nucleoplasm);GO:0005764(lysosome);GO:0005765(lysosomal membrane);GO:0005783(endoplasmic reticulum);GO:0005794(Golgi apparatus);GO:0005886(plasma membrane);GO:0005887(integral component of plasma membrane);GO:0006811(ion transport);GO:0008271(secondary active sulfate transmembrane transporter activity);GO:0008272(sulfate transport);GO:0008509(anion transmembrane transporter activity);GO:0015116(sulfate transmembrane transporter activity);GO:0015301(anion:anion antiporter activity);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0043231(intracellular membrane-bounded organelle);GO:0055085(transmembrane transport);GO:0070062(extracellular exosome);GO:0098656(anion transmembrane transport);GO:1902358(sulfate transmembrane transport)","NA","K14708","NA","solute carrier family 26 member 11 [Source:HGNC Symbol;Acc:HGNC:14471]",0,0,0,{"v":3.640388,"d":"3.64"},{"v":2.812156,"d":"2.81"},0,"-inf","-inf",{"v":2.59620012268938e-5,"d":"0.00"},{"v":0.00396137567141607,"d":"0.00"},"down","yes"]
[55242,0,"chr14","+",24232636,24239204,"ENST00000559910",10,1562,"ENSG00000100938","GMPR2","GO:0003824(catalytic activity);GO:0003920(GMP reductase activity);GO:0003938(IMP dehydrogenase activity);GO:0005829(cytosol);GO:0006144(purine nucleobase metabolic process);GO:0006163(purine nucleotide metabolic process);GO:0006164(purine nucleotide biosynthetic process);GO:0009117(nucleotide metabolic process);GO:0015951(purine ribonucleotide interconversion);GO:0016491(oxidoreductase activity);GO:0043101(purine-containing compound salvage);GO:0046037(GMP metabolic process);GO:0046872(metal ion binding);GO:0055114(oxidation-reduction process);GO:1902560(GMP reductase complex)","00230(Purine metabolism)","K00364","EC:1.7.1.7","guanosine monophosphate reductase 2 [Source:HGNC Symbol;Acc:HGNC:4377]",{"v":4.060214,"d":"4.06"},0,{"v":3.371897,"d":"3.37"},0,0,0,"inf","inf",{"v":2.60602473291616e-5,"d":"0.00"},{"v":0.00396137567141607,"d":"0.00"},"up","yes"]
[101958,0,"chr19","-",29698886,29715789,"ENST00000614091",3,4489,"ENSG00000131943","C19orf12","GO:0005737(cytoplasm);GO:0005739(mitochondrion);GO:0005783(endoplasmic reticulum);GO:0005829(cytosol);GO:0006914(autophagy);GO:0006915(apoptotic process);GO:0006979(response to oxidative stress);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0031966(mitochondrial membrane);GO:0051560(mitochondrial calcium ion homeostasis)","NA","K23168","NA","chromosome 19 open reading frame 12 [Source:HGNC Symbol;Acc:HGNC:25443]",{"v":1.323497,"d":"1.32"},{"v":1.223894,"d":"1.22"},0,0,0,0,"inf","inf",{"v":2.62651833814044e-5,"d":"0.00"},{"v":0.00396828192033629,"d":"0.00"},"up","yes"]
[167530,0,"chr6","+",13574584,13614558,"ENST00000379250",9,3727,"ENSG00000124523","SIRT5","GO:0003950(NAD+ ADP-ribosyltransferase activity);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005739(mitochondrion);GO:0005743(mitochondrial inner membrane);GO:0005758(mitochondrial intermembrane space);GO:0005759(mitochondrial matrix);GO:0005829(cytosol);GO:0006342(chromatin silencing);GO:0006471(protein ADP-ribosylation);GO:0006476(protein deacetylation);GO:0007005(mitochondrion organization);GO:0008270(zinc ion binding);GO:0010566(regulation of ketone biosynthetic process);GO:0010667(negative regulation of cardiac muscle cell apoptotic process);GO:0016787(hydrolase activity);GO:0031667(response to nutrient levels);GO:0034979(NAD-dependent protein deacetylase activity);GO:0036046(protein demalonylation);GO:0036047(peptidyl-lysine demalonylation);GO:0036048(protein desuccinylation);GO:0036049(peptidyl-lysine desuccinylation);GO:0036054(protein-malonyllysine demalonylase activity);GO:0036055(protein-succinyllysine desuccinylase activity);GO:0046872(metal ion binding);GO:0061697(protein-glutaryllysine deglutarylase activity);GO:0061698(protein deglutarylation);GO:0061699(peptidyl-lysine deglutarylation);GO:0070403(NAD+ binding);GO:2000378(negative regulation of reactive oxygen species metabolic process)","NA","K11415","EC:3.5.1.-","sirtuin 5 [Source:HGNC Symbol;Acc:HGNC:14933]",0,0,0,0,{"v":1.346396,"d":"1.35"},{"v":1.738993,"d":"1.74"},"-inf","-inf",{"v":2.63241382549145e-5,"d":"0.00"},{"v":0.00396828192033629,"d":"0.00"},"down","yes"]
[159683,0,"chr5","+",69371035,69414799,"ENST00000358030",16,2648,"ENSG00000152942","RAD17","GO:0000076(DNA replication checkpoint);GO:0000077(DNA damage checkpoint);GO:0000166(nucleotide binding);GO:0000781(chromosome, telomeric region);GO:0000790(nuclear chromatin);GO:0003682(chromatin binding);GO:0003689(DNA clamp loader activity);GO:0005515(protein binding);GO:0005524(ATP binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005730(nucleolus);GO:0006260(DNA replication);GO:0006281(DNA repair);GO:0006974(cellular response to DNA damage stimulus);GO:0007049(cell cycle);GO:0007093(mitotic cell cycle checkpoint);GO:0008156(negative regulation of DNA replication);GO:0031389(Rad17 RFC-like complex);GO:0033314(mitotic DNA replication checkpoint);GO:0042325(regulation of phosphorylation);GO:1901796(regulation of signal transduction by p53 class mediator)","NA","K06662","NA","RAD17 checkpoint clamp loader component [Source:HGNC Symbol;Acc:HGNC:9807]",{"v":1.332856,"d":"1.33"},{"v":4.339293,"d":"4.34"},0,0,0,0,"inf","inf",{"v":2.67201959896313e-5,"d":"0.00"},{"v":0.0040010820632288,"d":"0.00"},"up","yes"]
[76972,0,"chr16","-",69710782,69726560,"ENST00000439109",4,924,"ENSG00000181019","NQO1","GO:0003723(RNA binding);GO:0003955(NAD(P)H dehydrogenase (quinone) activity);GO:0004128(cytochrome-b5 reductase activity, acting on NAD(P)H);GO:0004784(superoxide dismutase activity);GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0006521(regulation of cellular amino acid metabolic process);GO:0006801(superoxide metabolic process);GO:0006805(xenobiotic metabolic process);GO:0006809(nitric oxide biosynthetic process);GO:0006979(response to oxidative stress);GO:0007271(synaptic transmission, cholinergic);GO:0007568(aging);GO:0007584(response to nutrient);GO:0009055(electron transfer activity);GO:0009636(response to toxic substance);GO:0014070(response to organic cyclic compound);GO:0016491(oxidoreductase activity);GO:0019430(removal of superoxide radicals);GO:0022900(electron transport chain);GO:0030425(dendrite);GO:0032355(response to estradiol);GO:0042802(identical protein binding);GO:0043025(neuronal cell body);GO:0043066(negative regulation of apoptotic process);GO:0043086(negative regulation of catalytic activity);GO:0043525(positive regulation of neuron apoptotic process);GO:0045471(response to ethanol);GO:0051602(response to electrical stimulus);GO:0055114(oxidation-reduction process);GO:0070301(cellular response to hydrogen peroxide);GO:0071248(cellular response to metal ion);GO:1901698(response to nitrogen compound);GO:1904880(response to hydrogen sulfide)","00130(Ubiquinone and other terpenoid-quinone biosynthesis);05200(Pathways in cancer);05225(Hepatocellular carcinoma);05418(Fluid shear stress and atherosclerosis)","K00355","EC:1.6.5.2","NAD(P)H quinone dehydrogenase 1 [Source:HGNC Symbol;Acc:HGNC:2874]",0,0,0,{"v":1.209976,"d":"1.21"},{"v":0.480081,"d":"0.48"},{"v":1.556716,"d":"1.56"},"-inf","-inf",{"v":2.67619857243215e-5,"d":"0.00"},{"v":0.0040010820632288,"d":"0.00"},"down","yes"]
[135090,0,"chr22","+",41621295,41664048,"ENST00000402580",13,2006,"ENSG00000196419","XRCC6","GO:0000166(nucleotide binding);GO:0000723(telomere maintenance);GO:0000783(nuclear telomere cap complex);GO:0000784(nuclear chromosome, telomeric region);GO:0002218(activation of innate immune response);GO:0002376(immune system process);GO:0003677(DNA binding);GO:0003684(damaged DNA binding);GO:0003690(double-stranded DNA binding);GO:0003691(double-stranded telomeric DNA binding);GO:0003723(RNA binding);GO:0003824(catalytic activity);GO:0004003(ATP-dependent DNA helicase activity);GO:0004386(helicase activity);GO:0005515(protein binding);GO:0005524(ATP binding);GO:0005576(extracellular region);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005667(transcription factor complex);GO:0005694(chromosome);GO:0005730(nucleolus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0006266(DNA ligation);GO:0006281(DNA repair);GO:0006303(double-strand break repair via nonhomologous end joining);GO:0006310(DNA recombination);GO:0006974(cellular response to DNA damage stimulus);GO:0007420(brain development);GO:0008022(protein C-terminus binding);GO:0008152(metabolic process);GO:0016020(membrane);GO:0016787(hydrolase activity);GO:0016829(lyase activity);GO:0030332(cyclin binding);GO:0032481(positive regulation of type I interferon production);GO:0032508(DNA duplex unwinding);GO:0032991(protein-containing complex);GO:0032993(protein-DNA complex);GO:0034774(secretory granule lumen);GO:0042162(telomeric DNA binding);GO:0043312(neutrophil degranulation);GO:0043564(Ku70:Ku80 complex);GO:0044212(transcription regulatory region DNA binding);GO:0044877(protein-containing complex binding);GO:0045087(innate immune response);GO:0045860(positive regulation of protein kinase activity);GO:0045892(negative regulation of transcription, DNA-templated);GO:0045893(positive regulation of transcription, DNA-templated);GO:0045944(positive regulation of transcription by RNA polymerase II);GO:0048660(regulation of smooth muscle cell proliferation);GO:0051290(protein heterotetramerization);GO:0051575(5'-deoxyribose-5-phosphate lyase activity);GO:0070419(nonhomologous end joining complex);GO:0071475(cellular hyperosmotic salinity response);GO:0071480(cellular response to gamma radiation);GO:0071481(cellular response to X-ray);GO:0075713(establishment of integrated proviral latency);GO:0097680(double-strand break repair via classical nonhomologous end joining);GO:1904813(ficolin-1-rich granule lumen)","03450(Non-homologous end-joining)","NA","NA","X-ray repair cross complementing 6 [Source:HGNC Symbol;Acc:HGNC:4055]",0,0,0,{"v":2.595422,"d":"2.60"},0,{"v":2.28564,"d":"2.29"},"-inf","-inf",{"v":2.68723201310652e-5,"d":"0.00"},{"v":0.00400111225558032,"d":"0.00"},"down","yes"]
[3666,0,"chr1","-",30931506,31065695,"ENST00000424085",18,4631,"ENSG00000134644","PUM1","GO:0000932(P-body);GO:0003723(RNA binding);GO:0003730(mRNA 3'-UTR binding);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0006417(regulation of translation);GO:0007283(spermatogenesis);GO:0008344(adult locomotory behavior);GO:0010494(cytoplasmic stress granule);GO:0010608(posttranscriptional regulation of gene expression);GO:0016441(posttranscriptional gene silencing);GO:0016607(nuclear speck);GO:0030154(cell differentiation);GO:0035196(production of miRNAs involved in gene silencing by miRNA);GO:0035198(miRNA binding);GO:0043488(regulation of mRNA stability);GO:0048863(stem cell differentiation);GO:0051726(regulation of cell cycle);GO:0051983(regulation of chromosome segregation);GO:0060964(regulation of gene silencing by miRNA);GO:0061157(mRNA destabilization);GO:1900246(positive regulation of RIG-I signaling pathway);GO:2000637(positive regulation of gene silencing by miRNA)","NA","K17943","NA","pumilio RNA binding family member 1 [Source:HGNC Symbol;Acc:HGNC:14957]",0,0,0,{"v":0.194734,"d":"0.19"},0,{"v":5.540278,"d":"5.54"},"-inf","-inf",{"v":2.71608226149222e-5,"d":"0.00"},{"v":0.00401376510055952,"d":"0.00"},"down","yes"]
[186587,0,"chr8","+",11769699,11787340,"ENST00000455213",6,2323,"ENSG00000154328","NEIL2","GO:0003676(nucleic acid binding);GO:0003677(DNA binding);GO:0003684(damaged DNA binding);GO:0003824(catalytic activity);GO:0003906(DNA-(apurinic or apyrimidinic site) endonuclease activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0005876(spindle microtubule);GO:0006281(DNA repair);GO:0006284(base-excision repair);GO:0006289(nucleotide-excision repair);GO:0006974(cellular response to DNA damage stimulus);GO:0008017(microtubule binding);GO:0008152(metabolic process);GO:0008270(zinc ion binding);GO:0015630(microtubule cytoskeleton);GO:0016787(hydrolase activity);GO:0016798(hydrolase activity, acting on glycosyl bonds);GO:0016799(hydrolase activity, hydrolyzing N-glycosyl compounds);GO:0016829(lyase activity);GO:0019104(DNA N-glycosylase activity);GO:0043231(intracellular membrane-bounded organelle);GO:0045008(depyrimidination);GO:0046872(metal ion binding);GO:0140078(class I DNA-(apurinic or apyrimidinic site) endonuclease activity)","03410(Base excision repair)","K10568","4.2.99.18;EC:3.2.2.-","nei like DNA glycosylase 2 [Source:HGNC Symbol;Acc:HGNC:18956]",{"v":3.35086,"d":"3.35"},0,{"v":1.939889,"d":"1.94"},0,0,0,"inf","inf",{"v":2.71782607965219e-5,"d":"0.00"},{"v":0.00401376510055952,"d":"0.00"},"up","yes"]
[130269,0,"chr21","+",37073271,37203103,"ENST00000355666",46,7712,"ENSG00000182670","TTC3","GO:0004842(ubiquitin-protein transferase activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005730(nucleolus);GO:0005829(cytosol);GO:0006511(ubiquitin-dependent protein catabolic process);GO:0016567(protein ubiquitination);GO:0016740(transferase activity);GO:0046872(metal ion binding);GO:0070936(protein K48-linked ubiquitination)","NA","K15712","EC:2.3.2.27","tetratricopeptide repeat domain 3 [Source:HGNC Symbol;Acc:HGNC:12393]",{"v":28.116148,"d":"28.12"},{"v":4.028632,"d":"4.03"},{"v":0.602501,"d":"0.60"},{"v":0.330813,"d":"0.33"},{"v":0.39544,"d":"0.40"},{"v":0.066858,"d":"0.07"},{"v":41.2896568071808,"d":"41.29"},{"v":5.36770852200799,"d":"5.37"},{"v":2.76676146726927e-5,"d":"0.00"},{"v":0.00405790513556861,"d":"0.00"},"up","yes"]
[204888,0,"chrX","-",101009542,101052070,"ENST00000372935",14,2921,"ENSG00000188917","TRMT2B","GO:0001510(RNA methylation);GO:0005515(protein binding);GO:0006396(RNA processing);GO:0008033(tRNA processing);GO:0008168(methyltransferase activity);GO:0008173(RNA methyltransferase activity);GO:0016740(transferase activity);GO:0030697(S-adenosylmethionine-dependent tRNA (m5U54) methyltransferase activity);GO:0032259(methylation)","NA","K15331","EC:2.1.1.35","tRNA methyltransferase 2 homolog B [Source:HGNC Symbol;Acc:HGNC:25748]",0,0,0,{"v":1.270127,"d":"1.27"},0,{"v":2.272987,"d":"2.27"},"-inf","-inf",{"v":2.77005360203968e-5,"d":"0.00"},{"v":0.00405790513556861,"d":"0.00"},"down","yes"]
[195548,0,"chr9","+",35605491,35610041,"ENST00000498522",9,2226,"ENSG00000107140","TESK1","GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0004712(protein serine/threonine/tyrosine kinase activity);GO:0004713(protein tyrosine kinase activity);GO:0005515(protein binding);GO:0005524(ATP binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0006468(protein phosphorylation);GO:0007283(spermatogenesis);GO:0008022(protein C-terminus binding);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0016740(transferase activity);GO:0018108(peptidyl-tyrosine phosphorylation);GO:0019901(protein kinase binding);GO:0030036(actin cytoskeleton organization);GO:0031410(cytoplasmic vesicle);GO:0031953(negative regulation of protein autophosphorylation);GO:0032880(regulation of protein localization);GO:0046872(metal ion binding);GO:0051496(positive regulation of stress fiber assembly);GO:0071901(negative regulation of protein serine/threonine kinase activity)","NA","K08841","EC:2.7.12.1","testis associated actin remodelling kinase 1 [Source:HGNC Symbol;Acc:HGNC:11731]",0,{"v":0.00115,"d":"0.00"},0,{"v":5.427289,"d":"5.43"},{"v":4.405077,"d":"4.41"},0,{"v":0.000116960658299335,"d":"0.00"},{"v":-13.0616890430839,"d":"-13.06"},{"v":2.8393987660795e-5,"d":"0.00"},{"v":0.00414278542858105,"d":"0.00"},"down","yes"]
[196485,0,"chr9","+",69205171,69255187,"ENST00000650084",23,4389,"ENSG00000119139","TJP2","GO:0004385(guanylate kinase activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0005912(adherens junction);GO:0005923(bicellular tight junction);GO:0016020(membrane);GO:0019904(protein domain specific binding);GO:0030054(cell junction);GO:0030674(protein binding, bridging);GO:0035329(hippo signaling);GO:0045296(cadherin binding);GO:0046037(GMP metabolic process);GO:0046710(GDP metabolic process);GO:0050892(intestinal absorption);GO:0090557(establishment of endothelial intestinal barrier);GO:0090559(regulation of membrane permeability)","04530(Tight junction);05110(Vibrio cholerae infection)","K06098","NA","tight junction protein 2 [Source:HGNC Symbol;Acc:HGNC:11828]",{"v":0.801367,"d":"0.80"},0,{"v":2.075347,"d":"2.08"},0,0,0,"inf","inf",{"v":2.88017516731492e-5,"d":"0.00"},{"v":0.00418547055314205,"d":"0.00"},"up","yes"]
[137349,0,"chr3","+",16174709,16231992,"ENST00000437509",10,2416,"ENSG00000131386","GALNT15","GO:0000139(Golgi membrane);GO:0004653(polypeptide N-acetylgalactosaminyltransferase activity);GO:0005794(Golgi apparatus);GO:0006486(protein glycosylation);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016266(O-glycan processing);GO:0016740(transferase activity);GO:0016757(transferase activity, transferring glycosyl groups);GO:0030133(transport vesicle);GO:0030246(carbohydrate binding);GO:0046872(metal ion binding)","00512(Mucin type O-glycan biosynthesis)","K00710","EC:2.4.1.41","polypeptide N-acetylgalactosaminyltransferase 15 [Source:HGNC Symbol;Acc:HGNC:21531]",{"v":2.424552,"d":"2.42"},{"v":7.528413,"d":"7.53"},0,{"v":0.002901,"d":"0.00"},0,0,{"v":3430.87383660807,"d":"3430.87"},{"v":11.7443603593637,"d":"11.74"},{"v":2.93621878410176e-5,"d":"0.00"},{"v":0.0042444872376503,"d":"0.00"},"up","yes"]
[201562,0,"chrX","+",13569622,13633575,"ENST00000380602",12,2385,"ENSG00000198759","EGFL6","GO:0005178(integrin binding);GO:0005509(calcium ion binding);GO:0005576(extracellular region);GO:0005604(basement membrane);GO:0005615(extracellular space);GO:0007155(cell adhesion);GO:0007275(multicellular organism development);GO:0010811(positive regulation of cell-substrate adhesion);GO:0016020(membrane);GO:0030154(cell differentiation);GO:0030198(extracellular matrix organization);GO:0031012(extracellular matrix)","NA","NA","NA","EGF like domain multiple 6 [Source:HGNC Symbol;Acc:HGNC:3235]",0,0,0,{"v":0.536928,"d":"0.54"},{"v":0.420221,"d":"0.42"},{"v":0.215188,"d":"0.22"},"-inf","-inf",{"v":2.94415299721408e-5,"d":"0.00"},{"v":0.0042444872376503,"d":"0.00"},"down","yes"]
[114131,0,"chr2","+",74529725,74533152,"ENST00000462909",9,1294,"ENSG00000115317","HTRA2","GO:0000785(chromatin);GO:0004252(serine-type endopeptidase activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005739(mitochondrion);GO:0005758(mitochondrial intermembrane space);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005829(cytosol);GO:0005856(cytoskeleton);GO:0006508(proteolysis);GO:0006672(ceramide metabolic process);GO:0006915(apoptotic process);GO:0007005(mitochondrion organization);GO:0007568(aging);GO:0007628(adult walking behavior);GO:0008233(peptidase activity);GO:0008236(serine-type peptidase activity);GO:0008344(adult locomotory behavior);GO:0008630(intrinsic apoptotic signaling pathway in response to DNA damage);GO:0009635(response to herbicide);GO:0009898(cytoplasmic side of plasma membrane);GO:0010822(positive regulation of mitochondrion organization);GO:0010942(positive regulation of cell death);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016540(protein autoprocessing);GO:0016787(hydrolase activity);GO:0019742(pentacyclic triterpenoid metabolic process);GO:0030900(forebrain development);GO:0031966(mitochondrial membrane);GO:0034599(cellular response to oxidative stress);GO:0034605(cellular response to heat);GO:0035458(cellular response to interferon-beta);GO:0035631(CD40 receptor complex);GO:0040014(regulation of multicellular organism growth);GO:0042802(identical protein binding);GO:0043065(positive regulation of apoptotic process);GO:0043280(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process);GO:0044257(cellular protein catabolic process);GO:0045786(negative regulation of cell cycle);GO:0048666(neuron development);GO:0051082(unfolded protein binding);GO:0060548(negative regulation of cell death);GO:0070207(protein homotrimerization);GO:0071300(cellular response to retinoic acid);GO:0071363(cellular response to growth factor stimulus);GO:0097193(intrinsic apoptotic signaling pathway);GO:0097194(execution phase of apoptosis);GO:1901215(negative regulation of neuron death);GO:1902176(negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway);GO:1903146(regulation of autophagy of mitochondrion);GO:1903955(positive regulation of protein targeting to mitochondrion);GO:1904924(negative regulation of mitophagy in response to mitochondrial depolarization);GO:1905370(serine-type endopeptidase complex);GO:2001241(positive regulation of extrinsic apoptotic signaling pathway in absence of ligand);GO:2001269(positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway)","04210(Apoptosis);04215(Apoptosis - multiple species);05012(Parkinson disease)","K08669","EC:3.4.21.108","HtrA serine peptidase 2 [Source:HGNC Symbol;Acc:HGNC:14348]",{"v":2.201403,"d":"2.20"},{"v":9.257925,"d":"9.26"},0,0,0,0,"inf","inf",{"v":3.00018373317431e-5,"d":"0.00"},{"v":0.00429243290409983,"d":"0.00"},"up","yes"]
[2499,0,"chr1","+",21440313,21484900,"ENST00000318249",15,3591,"ENSG00000142794","NBPF3","GO:0005737(cytoplasm)","NA","NA","NA","NBPF member 3 [Source:HGNC Symbol;Acc:HGNC:25076]",0,{"v":1.512212,"d":"1.51"},{"v":1.347144,"d":"1.35"},0,0,0,"inf","inf",{"v":3.01328123427656e-5,"d":"0.00"},{"v":0.00429243290409983,"d":"0.00"},"up","yes"]
[135888,0,"chr22","-",50217689,50244971,"ENST00000439308",25,6078,"ENSG00000128159","TUBGCP6","GO:0000226(microtubule cytoskeleton organization);GO:0000278(mitotic cell cycle);GO:0000922(spindle pole);GO:0000923(equatorial microtubule organizing center);GO:0000930(gamma-tubulin complex);GO:0005737(cytoplasm);GO:0005813(centrosome);GO:0005815(microtubule organizing center);GO:0005829(cytosol);GO:0005856(cytoskeleton);GO:0005874(microtubule);GO:0007020(microtubule nucleation);GO:0008017(microtubule binding);GO:0008274(gamma-tubulin ring complex);GO:0008275(gamma-tubulin small complex);GO:0016020(membrane);GO:0031122(cytoplasmic microtubule organization);GO:0043015(gamma-tubulin binding);GO:0051011(microtubule minus-end binding);GO:0051225(spindle assembly);GO:0051321(meiotic cell cycle);GO:0051415(microtubule nucleation by interphase microtubule organizing center)","NA","K16573","NA","tubulin gamma complex associated protein 6 [Source:HGNC Symbol;Acc:HGNC:18127]",{"v":1.649789,"d":"1.65"},0,{"v":0.54669,"d":"0.55"},0,0,0,"inf","inf",{"v":3.02227744570387e-5,"d":"0.00"},{"v":0.00429243290409983,"d":"0.00"},"up","yes"]
[163592,0,"chr5","+",140691609,140698628,"ENST00000508522",12,1562,"ENSG00000112855","HARS2","GO:0000166(nucleotide binding);GO:0003723(RNA binding);GO:0004812(aminoacyl-tRNA ligase activity);GO:0004821(histidine-tRNA ligase activity);GO:0005515(protein binding);GO:0005524(ATP binding);GO:0005737(cytoplasm);GO:0005739(mitochondrion);GO:0005759(mitochondrial matrix);GO:0005829(cytosol);GO:0006412(translation);GO:0006418(tRNA aminoacylation for protein translation);GO:0006427(histidyl-tRNA aminoacylation);GO:0016874(ligase activity);GO:0042802(identical protein binding);GO:0042803(protein homodimerization activity)","00970(Aminoacyl-tRNA biosynthesis)","K01892","EC:6.1.1.21","histidyl-tRNA synthetase 2, mitochondrial [Source:HGNC Symbol;Acc:HGNC:4817]",{"v":3.344213,"d":"3.34"},{"v":3.179114,"d":"3.18"},0,0,0,0,"inf","inf",{"v":3.0246705847772e-5,"d":"0.00"},{"v":0.00429243290409983,"d":"0.00"},"up","yes"]
[82345,0,"chr17","-",18244836,18245968,"ENST00000581858",4,644,"ENSG00000177731","FLII","GO:0003779(actin binding);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0005815(microtubule organizing center);GO:0005829(cytosol);GO:0005856(cytoskeleton);GO:0005903(brush border);GO:0005925(focal adhesion);GO:0007275(multicellular organism development);GO:0030036(actin cytoskeleton organization);GO:0030054(cell junction);GO:0051014(actin filament severing);GO:0051015(actin filament binding)","NA","NA","NA","FLII, actin remodeling protein [Source:HGNC Symbol;Acc:HGNC:3750]",0,0,0,0,{"v":7.51663,"d":"7.52"},{"v":7.594412,"d":"7.59"},"-inf","-inf",{"v":3.08813420776847e-5,"d":"0.00"},{"v":0.00436544419331628,"d":"0.00"},"down","yes"]
[65088,0,"chr15","+",63042751,63071912,"ENST00000357980",10,1800,"ENSG00000140416","TPM1","GO:0001701(in utero embryonic development);GO:0001725(stress fiber);GO:0003065(positive regulation of heart rate by epinephrine);GO:0003779(actin binding);GO:0005200(structural constituent of cytoskeleton);GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005856(cytoskeleton);GO:0005862(muscle thin filament tropomyosin);GO:0005884(actin filament);GO:0006936(muscle contraction);GO:0006937(regulation of muscle contraction);GO:0007010(cytoskeleton organization);GO:0007015(actin filament organization);GO:0008016(regulation of heart contraction);GO:0008092(cytoskeletal protein binding);GO:0008307(structural constituent of muscle);GO:0008360(regulation of cell shape);GO:0015629(actin cytoskeleton);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0030016(myofibril);GO:0030017(sarcomere);GO:0030049(muscle filament sliding);GO:0030336(negative regulation of cell migration);GO:0031529(ruffle organization);GO:0032059(bleb);GO:0032587(ruffle membrane);GO:0032781(positive regulation of ATPase activity);GO:0034614(cellular response to reactive oxygen species);GO:0042060(wound healing);GO:0042802(identical protein binding);GO:0042803(protein homodimerization activity);GO:0045214(sarcomere organization);GO:0045785(positive regulation of cell adhesion);GO:0046982(protein heterodimerization activity);GO:0051015(actin filament binding);GO:0051496(positive regulation of stress fiber assembly);GO:0055010(ventricular cardiac muscle tissue morphogenesis);GO:0060048(cardiac muscle contraction);GO:1904706(negative regulation of vascular smooth muscle cell proliferation);GO:1904753(negative regulation of vascular associated smooth muscle cell migration)","04260(Cardiac muscle contraction);04261(Adrenergic signaling in cardiomyocytes);05206(MicroRNAs in cancer);05410(Hypertrophic cardiomyopathy (HCM));05414(Dilated cardiomyopathy (DCM))","K10373","NA","tropomyosin 1 [Source:HGNC Symbol;Acc:HGNC:12010]",0,{"v":2.225652,"d":"2.23"},{"v":3.49844,"d":"3.50"},0,0,0,"inf","inf",{"v":3.14222655138611e-5,"d":"0.00"},{"v":0.00442469343456812,"d":"0.00"},"up","yes"]
[205395,0,"chrX","+",108439924,108697545,"ENST00000361603",51,6427,"ENSG00000188153","COL4A5","GO:0005201(extracellular matrix structural constituent);GO:0005576(extracellular region);GO:0005581(collagen trimer);GO:0005587(collagen type IV trimer);GO:0005604(basement membrane);GO:0005615(extracellular space);GO:0005788(endoplasmic reticulum lumen);GO:0007528(neuromuscular junction development);GO:0030020(extracellular matrix structural constituent conferring tensile strength);GO:0030198(extracellular matrix organization);GO:0031012(extracellular matrix);GO:0031594(neuromuscular junction);GO:0038063(collagen-activated tyrosine kinase receptor signaling pathway);GO:0062023(collagen-containing extracellular matrix)","04151(PI3K-Akt signaling pathway);04510(Focal adhesion);04512(ECM-receptor interaction);04926(Relaxin signaling pathway);04933(AGE-RAGE signaling pathway in diabetic complications);04974(Protein digestion and absorption);05146(Amoebiasis);05165(Human papillomavirus infection);05200(Pathways in cancer);05222(Small cell lung cancer)","K06237","NA","collagen type IV alpha 5 chain [Source:HGNC Symbol;Acc:HGNC:2207]",0,0,0,{"v":0.589295,"d":"0.59"},0,{"v":0.760247,"d":"0.76"},"-inf","-inf",{"v":3.17616477637998e-5,"d":"0.00"},{"v":0.00445521491605732,"d":"0.00"},"down","yes"]
[13845,0,"chr1","-",169463929,169485931,"ENST00000367804",5,2976,"ENSG00000117479","SLC19A2","GO:0005515(protein binding);GO:0005886(plasma membrane);GO:0008517(folic acid transmembrane transporter activity);GO:0015234(thiamine transmembrane transporter activity);GO:0015884(folic acid transport);GO:0015888(thiamine transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0035461(vitamin transmembrane transport);GO:0042723(thiamine-containing compound metabolic process);GO:0051180(vitamin transport);GO:0055085(transmembrane transport);GO:0071934(thiamine transmembrane transport);GO:0090482(vitamin transmembrane transporter activity)","04977(Vitamin digestion and absorption)","K14610","NA","solute carrier family 19 member 2 [Source:HGNC Symbol;Acc:HGNC:10938]",0,0,0,0,{"v":1.383739,"d":"1.38"},{"v":1.862117,"d":"1.86"},"-inf","-inf",{"v":3.20996035068451e-5,"d":"0.00"},{"v":0.00448530229001416,"d":"0.00"},"down","yes"]
[127688,0,"chr20","-",49363877,49482668,"ENST00000371741",2,11871,"ENSG00000158445","KCNB1","GO:0001508(action potential);GO:0005216(ion channel activity);GO:0005244(voltage-gated ion channel activity);GO:0005249(voltage-gated potassium channel activity);GO:0005251(delayed rectifier potassium channel activity);GO:0005267(potassium channel activity);GO:0005515(protein binding);GO:0005886(plasma membrane);GO:0006811(ion transport);GO:0006813(potassium ion transport);GO:0006887(exocytosis);GO:0006904(vesicle docking involved in exocytosis);GO:0007215(glutamate receptor signaling pathway);GO:0008076(voltage-gated potassium channel complex);GO:0010701(positive regulation of norepinephrine secretion);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016328(lateral plasma membrane);GO:0030054(cell junction);GO:0030424(axon);GO:0030425(dendrite);GO:0031669(cellular response to nutrient levels);GO:0032590(dendrite membrane);GO:0032809(neuronal cell body membrane);GO:0033605(positive regulation of catecholamine secretion);GO:0034765(regulation of ion transmembrane transport);GO:0042383(sarcolemma);GO:0042593(glucose homeostasis);GO:0042995(cell projection);GO:0043005(neuron projection);GO:0043204(perikaryon);GO:0044325(ion channel binding);GO:0045202(synapse);GO:0045211(postsynaptic membrane);GO:0045956(positive regulation of calcium ion-dependent exocytosis);GO:0046676(negative regulation of insulin secretion);GO:0046982(protein heterodimerization activity);GO:0050796(regulation of insulin secretion);GO:0051260(protein homooligomerization);GO:0055085(transmembrane transport);GO:0071333(cellular response to glucose stimulus);GO:0071805(potassium ion transmembrane transport);GO:0072659(protein localization to plasma membrane);GO:0090314(positive regulation of protein targeting to membrane);GO:0098900(regulation of action potential);GO:1900454(positive regulation of long-term synaptic depression);GO:2000671(regulation of motor neuron apoptotic process)","NA","NA","NA","potassium voltage-gated channel subfamily B member 1 [Source:HGNC Symbol;Acc:HGNC:6231]",0,0,0,{"v":0.323936,"d":"0.32"},0,{"v":0.388856,"d":"0.39"},"-inf","-inf",{"v":3.22543082777084e-5,"d":"0.00"},{"v":0.00448965141658677,"d":"0.00"},"down","yes"]
[109788,0,"chr2","+",9473818,9488444,"ENST00000482918",6,863,"ENSG00000134330","IAH1","GO:0006629(lipid metabolic process);GO:0016042(lipid catabolic process);GO:0016787(hydrolase activity);GO:0016788(hydrolase activity, acting on ester bonds)","NA","NA","NA","isoamyl acetate hydrolyzing esterase 1 (putative) [Source:HGNC Symbol;Acc:HGNC:27696]",0,0,0,0,{"v":4.080865,"d":"4.08"},{"v":8.310079,"d":"8.31"},"-inf","-inf",{"v":3.25330748821496e-5,"d":"0.00"},{"v":0.00451117026896372,"d":"0.00"},"down","yes"]
[144062,0,"chr3","-",129129374,129156889,"ENST00000471497",6,1211,"ENSG00000240682","ISY1","GO:0000350(generation of catalytic spliceosome for second transesterification step);GO:0000384(first spliceosomal transesterification activity);GO:0000389(mRNA 3'-splice site recognition);GO:0000398(mRNA splicing, via spliceosome);GO:0000974(Prp19 complex);GO:0003723(RNA binding);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005681(spliceosomal complex);GO:0006283(transcription-coupled nucleotide-excision repair);GO:0006397(mRNA processing);GO:0008380(RNA splicing);GO:0071006(U2-type catalytic step 1 spliceosome);GO:0071013(catalytic step 2 spliceosome);GO:0071014(post-mRNA release spliceosomal complex);GO:0071020(post-spliceosomal complex)","03040(Spliceosome)","K12870","NA","ISY1 splicing factor homolog [Source:HGNC Symbol;Acc:HGNC:29201]",0,{"v":2.38368,"d":"2.38"},{"v":7.211057,"d":"7.21"},0,0,0,"inf","inf",{"v":3.28369337522911e-5,"d":"0.00"},{"v":0.00452099747300262,"d":"0.00"},"up","yes"]
[47069,0,"chr12","-",101394944,101407461,"ENST00000536227",6,1322,"ENSG00000120805","ARL1","GO:0000139(Golgi membrane);GO:0000166(nucleotide binding);GO:0003924(GTPase activity);GO:0005525(GTP binding);GO:0005737(cytoplasm);GO:0005794(Golgi apparatus);GO:0005802(trans-Golgi network);GO:0005829(cytosol);GO:0006886(intracellular protein transport);GO:0007030(Golgi organization);GO:0008047(enzyme activator activity);GO:0009404(toxin metabolic process);GO:0016020(membrane);GO:0016192(vesicle-mediated transport);GO:0019904(protein domain specific binding);GO:0031584(activation of phospholipase D activity);GO:0032588(trans-Golgi network membrane);GO:0034067(protein localization to Golgi apparatus);GO:0042147(retrograde transport, endosome to Golgi);GO:0046872(metal ion binding);GO:0048193(Golgi vesicle transport)","NA","NA","NA","ADP ribosylation factor like GTPase 1 [Source:HGNC Symbol;Acc:HGNC:692]",0,0,0,{"v":13.188165,"d":"13.19"},0,{"v":0.970237,"d":"0.97"},"-inf","-inf",{"v":3.28892854901197e-5,"d":"0.00"},{"v":0.00452099747300262,"d":"0.00"},"down","yes"]
[185011,0,"chr7","-",144254096,144355368,"ENST00000487102",3,761,"ENSG00000284644","AC074386","NA","NA","NA","NA","novel transcript, antisense to OR2A1 and ARHGEF5",{"v":1.333967,"d":"1.33"},{"v":1.1198,"d":"1.12"},{"v":0.938552,"d":"0.94"},0,0,0,"inf","inf",{"v":3.2977273062089e-5,"d":"0.00"},{"v":0.00452099747300262,"d":"0.00"},"up","yes"]
[153274,0,"chr4","-",89724099,89836976,"ENST00000420646",5,3127,"ENSG00000145335","SNCA","GO:0000122(negative regulation of transcription by RNA polymerase II);GO:0000149(SNARE binding);GO:0000287(magnesium ion binding);GO:0001774(microglial cell activation);GO:0001921(positive regulation of receptor recycling);GO:0001933(negative regulation of protein phosphorylation);GO:0001956(positive regulation of neurotransmitter secretion);GO:0001963(synaptic transmission, dopaminergic);GO:0003779(actin binding);GO:0005507(copper ion binding);GO:0005509(calcium ion binding);GO:0005515(protein binding);GO:0005543(phospholipid binding);GO:0005576(extracellular region);GO:0005615(extracellular space);GO:0005634(nucleus);GO:0005640(nuclear outer membrane);GO:0005737(cytoplasm);GO:0005739(mitochondrion);GO:0005741(mitochondrial outer membrane);GO:0005743(mitochondrial inner membrane);GO:0005747(mitochondrial respiratory chain complex I);GO:0005758(mitochondrial intermembrane space);GO:0005759(mitochondrial matrix);GO:0005764(lysosome);GO:0005791(rough endoplasmic reticulum);GO:0005794(Golgi apparatus);GO:0005829(cytosol);GO:0005840(ribosome);GO:0005856(cytoskeleton);GO:0005886(plasma membrane);GO:0005938(cell cortex);GO:0006631(fatty acid metabolic process);GO:0006638(neutral lipid metabolic process);GO:0006644(phospholipid metabolic process);GO:0006915(apoptotic process);GO:0006919(activation of cysteine-type endopeptidase activity involved in apoptotic process);GO:0007006(mitochondrial membrane organization);GO:0007268(chemical synaptic transmission);GO:0007568(aging);GO:0008017(microtubule binding);GO:0008021(synaptic vesicle);GO:0008198(ferrous iron binding);GO:0008270(zinc ion binding);GO:0008344(adult locomotory behavior);GO:0010040(response to iron(II) ion);GO:0010517(regulation of phospholipase activity);GO:0010642(negative regulation of platelet-derived growth factor receptor signaling pathway);GO:0014048(regulation of glutamate secretion);GO:0014059(regulation of dopamine secretion);GO:0015629(actin cytoskeleton);GO:0016020(membrane);GO:0016079(synaptic vesicle exocytosis);GO:0016082(synaptic vesicle priming);GO:0016234(inclusion body);GO:0016491(oxidoreductase activity);GO:0019894(kinesin binding);GO:0019899(enzyme binding);GO:0019904(protein domain specific binding);GO:0022898(regulation of transmembrane transporter activity);GO:0030054(cell junction);GO:0030424(axon);GO:0030426(growth cone);GO:0030544(Hsp70 protein binding);GO:0030659(cytoplasmic vesicle membrane);GO:0030672(synaptic vesicle membrane);GO:0031092(platelet alpha granule membrane);GO:0031115(negative regulation of microtubule polymerization);GO:0031623(receptor internalization);GO:0031648(protein destabilization);GO:0032026(response to magnesium ion);GO:0032410(negative regulation of transporter activity);GO:0032496(response to lipopolysaccharide);GO:0032769(negative regulation of monooxygenase activity);GO:0033138(positive regulation of peptidyl-serine phosphorylation);GO:0034341(response to interferon-gamma);GO:0034599(cellular response to oxidative stress);GO:0035067(negative regulation of histone acetylation);GO:0035493(SNARE complex assembly);GO:0040012(regulation of locomotion);GO:0042220(response to cocaine);GO:0042393(histone binding);GO:0042416(dopamine biosynthetic process);GO:0042417(dopamine metabolic process);GO:0042493(response to drug);GO:0042775(mitochondrial ATP synthesis coupled electron transport);GO:0042802(identical protein binding);GO:0043014(alpha-tubulin binding);GO:0043025(neuronal cell body);GO:0043027(cysteine-type endopeptidase inhibitor activity involved in apoptotic process);GO:0043030(regulation of macrophage activation);GO:0043065(positive regulation of apoptotic process);GO:0043066(negative regulation of apoptotic process);GO:0043154(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process);GO:0043195(terminal bouton);GO:0043231(intracellular membrane-bounded organelle);GO:0043274(phospholipase binding);GO:0043524(negative regulation of neuron apoptotic process);GO:0043679(axon terminus);GO:0044212(transcription regulatory region DNA binding);GO:0044267(cellular protein metabolic process);GO:0044344(cellular response to fibroblast growth factor stimulus);GO:0045202(synapse);GO:0045807(positive regulation of endocytosis);GO:0045920(negative regulation of exocytosis);GO:0045921(positive regulation of exocytosis);GO:0045963(negative regulation of dopamine metabolic process);GO:0046872(metal ion binding);GO:0046928(regulation of neurotransmitter secretion);GO:0047485(protein N-terminus binding);GO:0048148(behavioral response to cocaine);GO:0048156(tau protein binding);GO:0048168(regulation of neuronal synaptic plasticity);GO:0048169(regulation of long-term neuronal synaptic plasticity);GO:0048471(perinuclear region of cytoplasm);GO:0048487(beta-tubulin binding);GO:0048488(synaptic vesicle endocytosis);GO:0048489(synaptic vesicle transport);GO:0050729(positive regulation of inflammatory response);GO:0050806(positive regulation of synaptic transmission);GO:0050808(synapse organization);GO:0050812(regulation of acyl-CoA biosynthetic process);GO:0051219(phosphoprotein binding);GO:0051259(protein complex oligomerization);GO:0051262(protein tetramerization);GO:0051281(positive regulation of release of sequestered calcium ion into cytosol);GO:0051583(dopamine uptake involved in synaptic transmission);GO:0051585(negative regulation of dopamine uptake involved in synaptic transmission);GO:0051612(negative regulation of serotonin uptake);GO:0051621(regulation of norepinephrine uptake);GO:0051622(negative regulation of norepinephrine uptake);GO:0055114(oxidation-reduction process);GO:0060079(excitatory postsynaptic potential);GO:0060291(long-term synaptic potentiation);GO:0060732(positive regulation of inositol phosphate biosynthetic process);GO:0061024(membrane organization);GO:0070495(negative regulation of thrombin-activated receptor signaling pathway);GO:0070555(response to interleukin-1);GO:0070840(dynein complex binding);GO:0071280(cellular response to copper ion);GO:0071872(cellular response to epinephrine stimulus);GO:0071902(positive regulation of protein serine/threonine kinase activity);GO:0097435(supramolecular fiber organization);GO:0098793(presynapse);GO:0098794(postsynapse);GO:0099512(supramolecular fiber);GO:1901214(regulation of neuron death);GO:1901215(negative regulation of neuron death);GO:1901216(positive regulation of neuron death);GO:1902957(negative regulation of mitochondrial electron transport, NADH to ubiquinone);GO:1903136(cuprous ion binding);GO:1903284(positive regulation of glutathione peroxidase activity);GO:1903285(positive regulation of hydrogen peroxide catabolic process);GO:1903421(regulation of synaptic vesicle recycling);GO:1903426(regulation of reactive oxygen species biosynthetic process);GO:1904307(response to desipramine);GO:1904715(negative regulation of chaperone-mediated autophagy);GO:1905606(regulation of presynapse assembly);GO:2000377(regulation of reactive oxygen species metabolic process)","05010(Alzheimer disease);05012(Parkinson disease)","K04528","NA","synuclein alpha [Source:HGNC Symbol;Acc:HGNC:11138]",{"v":1.840519,"d":"1.84"},{"v":1.199148,"d":"1.20"},0,0,0,0,"inf","inf",{"v":3.35061731977661e-5,"d":"0.00"},{"v":0.0045762378656949,"d":"0.00"},"up","yes"]
[192831,0,"chr8","+",132775358,132845923,"ENST00000220847",20,3297,"ENSG00000129292","PHF20L1","GO:0005515(protein binding);GO:0005634(nucleus);GO:0006355(regulation of transcription, DNA-templated);GO:0046872(metal ion binding)","NA","K18402","NA","PHD finger protein 20 like 1 [Source:HGNC Symbol;Acc:HGNC:24280]",{"v":0.858636,"d":"0.86"},{"v":1.031149,"d":"1.03"},{"v":1.312469,"d":"1.31"},{"v":0.009443,"d":"0.01"},{"v":0.018838,"d":"0.02"},{"v":0.050205,"d":"0.05"},{"v":40.8003210763703,"d":"40.80"},{"v":5.35050860035532,"d":"5.35"},{"v":3.37969904847324e-5,"d":"0.00"},{"v":0.00459866915472033,"d":"0.00"},"up","yes"]
[199119,0,"chr9","+",125748199,125967377,"ENST00000447726",9,2789,"ENSG00000167081","PBX3","GO:0000980(RNA polymerase II distal enhancer sequence-specific DNA binding);GO:0000981(DNA-binding transcription factor activity, RNA polymerase II-specific);GO:0001228(DNA-binding transcription activator activity, RNA polymerase II-specific);GO:0002087(regulation of respiratory gaseous exchange by neurological system process);GO:0003677(DNA binding);GO:0003700(DNA-binding transcription factor activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005667(transcription factor complex);GO:0006355(regulation of transcription, DNA-templated);GO:0007387(anterior compartment pattern formation);GO:0007388(posterior compartment specification);GO:0007585(respiratory gaseous exchange);GO:0008344(adult locomotory behavior);GO:0021516(dorsal spinal cord development);GO:0043565(sequence-specific DNA binding);GO:0045944(positive regulation of transcription by RNA polymerase II);GO:0048666(neuron development)","05202(Transcriptional misregulation in cancer)","K15610","NA","PBX homeobox 3 [Source:HGNC Symbol;Acc:HGNC:8634]",0,{"v":3.363721,"d":"3.36"},{"v":0.888116,"d":"0.89"},0,0,0,"inf","inf",{"v":3.49993265163276e-5,"d":"0.00"},{"v":0.00474449825499322,"d":"0.00"},"up","yes"]
[120131,0,"chr2","+",188991674,188994308,"ENST00000450867",5,268,"ENSG00000168542","COL3A1","GO:0001501(skeletal system development);GO:0001568(blood vessel development);GO:0002020(protease binding);GO:0005178(integrin binding);GO:0005201(extracellular matrix structural constituent);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0005581(collagen trimer);GO:0005586(collagen type III trimer);GO:0005615(extracellular space);GO:0005788(endoplasmic reticulum lumen);GO:0007160(cell-matrix adhesion);GO:0007179(transforming growth factor beta receptor signaling pathway);GO:0007229(integrin-mediated signaling pathway);GO:0007507(heart development);GO:0009314(response to radiation);GO:0009612(response to mechanical stimulus);GO:0018149(peptide cross-linking);GO:0021987(cerebral cortex development);GO:0030020(extracellular matrix structural constituent conferring tensile strength);GO:0030168(platelet activation);GO:0030198(extracellular matrix organization);GO:0030199(collagen fibril organization);GO:0031012(extracellular matrix);GO:0034097(response to cytokine);GO:0035025(positive regulation of Rho protein signal transduction);GO:0042060(wound healing);GO:0043588(skin development);GO:0046332(SMAD binding);GO:0046872(metal ion binding);GO:0048407(platelet-derived growth factor binding);GO:0048565(digestive tract development);GO:0050776(regulation of immune response);GO:0050777(negative regulation of immune response);GO:0060414(aorta smooth muscle tissue morphogenesis);GO:0062023(collagen-containing extracellular matrix);GO:0071230(cellular response to amino acid stimulus);GO:0097435(supramolecular fiber organization);GO:2001223(negative regulation of neuron migration)","04611(Platelet activation);04926(Relaxin signaling pathway);04933(AGE-RAGE signaling pathway in diabetic complications);04974(Protein digestion and absorption);05146(Amoebiasis)","K19720","NA","collagen type III alpha 1 chain [Source:HGNC Symbol;Acc:HGNC:2201]",{"v":3.66934,"d":"3.67"},{"v":3.616243,"d":"3.62"},{"v":2.233308,"d":"2.23"},0,0,0,"inf","inf",{"v":3.54847691471441e-5,"d":"0.00"},{"v":0.00479242253946373,"d":"0.00"},"up","yes"]
[24466,0,"chr10","+",113691972,113730907,"ENST00000621607",7,2378,"ENSG00000165806","CASP7","GO:0004190(aspartic-type endopeptidase activity);GO:0004197(cysteine-type endopeptidase activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0006508(proteolysis);GO:0006915(apoptotic process);GO:0007507(heart development);GO:0007568(aging);GO:0008233(peptidase activity);GO:0008234(cysteine-type peptidase activity);GO:0009411(response to UV);GO:0016485(protein processing);GO:0016787(hydrolase activity);GO:0043231(intracellular membrane-bounded organelle);GO:0051146(striated muscle cell differentiation);GO:0051402(neuron apoptotic process);GO:0071887(leukocyte apoptotic process);GO:0072734(cellular response to staurosporine);GO:0097153(cysteine-type endopeptidase activity involved in apoptotic process);GO:0097194(execution phase of apoptosis);GO:0097200(cysteine-type endopeptidase activity involved in execution phase of apoptosis)","04210(Apoptosis);04215(Apoptosis - multiple species);04668(TNF signaling pathway);04932(Non-alcoholic fatty liver disease (NAFLD));05010(Alzheimer disease);05133(Pertussis);05134(Legionellosis);05200(Pathways in cancer)","NA","NA","caspase 7 [Source:HGNC Symbol;Acc:HGNC:1508]",0,{"v":7.119548,"d":"7.12"},{"v":0.654938,"d":"0.65"},0,0,0,"inf","inf",{"v":3.57160364364971e-5,"d":"0.00"},{"v":0.00480543940274763,"d":"0.00"},"up","yes"]
[206139,0,"chrX","-",132369317,132413575,"ENST00000538204",7,11294,"ENSG00000076770","MBNL3","GO:0000381(regulation of alternative mRNA splicing, via spliceosome);GO:0003723(RNA binding);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0006397(mRNA processing);GO:0007275(multicellular organism development);GO:0008380(RNA splicing);GO:0043484(regulation of RNA splicing);GO:0045662(negative regulation of myoblast differentiation);GO:0046872(metal ion binding)","NA","K14943","NA","muscleblind like splicing regulator 3 [Source:HGNC Symbol;Acc:HGNC:20564]",0,0,0,{"v":0.256562,"d":"0.26"},{"v":0.59034,"d":"0.59"},0,"-inf","-inf",{"v":3.58456944163118e-5,"d":"0.00"},{"v":0.00480543940274763,"d":"0.00"},"down","yes"]
[175895,0,"chr6","+",169751625,169781520,"ENST00000392095",17,1908,"ENSG00000130023","ERMARD","GO:0003674(molecular_function);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0007275(multicellular organism development);GO:0008150(biological_process);GO:0016020(membrane);GO:0016021(integral component of membrane)","NA","NA","NA","ER membrane associated RNA degradation [Source:HGNC Symbol;Acc:HGNC:21056]",0,0,0,{"v":2.42697,"d":"2.43"},0,{"v":1.771931,"d":"1.77"},"-inf","-inf",{"v":3.68397601666864e-5,"d":"0.00"},{"v":0.00492054590755778,"d":"0.00"},"down","yes"]
[66147,0,"chr15","+",72686179,72738475,"ENST00000395205",15,2450,"ENSG00000140463","BBS4","GO:0000226(microtubule cytoskeleton organization);GO:0000242(pericentriolar material);GO:0000281(mitotic cytokinesis);GO:0001103(RNA polymerase II repressing transcription factor binding);GO:0001750(photoreceptor outer segment);GO:0001764(neuron migration);GO:0001843(neural tube closure);GO:0001895(retina homeostasis);GO:0001917(photoreceptor inner segment);GO:0001947(heart looping);GO:0003085(negative regulation of systemic arterial blood pressure);GO:0003777(microtubule motor activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005813(centrosome);GO:0005814(centriole);GO:0005815(microtubule organizing center);GO:0005829(cytosol);GO:0005856(cytoskeleton);GO:0005886(plasma membrane);GO:0005929(cilium);GO:0007098(centrosome cycle);GO:0007286(spermatid development);GO:0007601(visual perception);GO:0007608(sensory perception of smell);GO:0008104(protein localization);GO:0010629(negative regulation of gene expression);GO:0015031(protein transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016358(dendrite development);GO:0019216(regulation of lipid metabolic process);GO:0021591(ventricular system development);GO:0021756(striatum development);GO:0021766(hippocampus development);GO:0021987(cerebral cortex development);GO:0030030(cell projection organization);GO:0030534(adult behavior);GO:0030837(negative regulation of actin filament polymerization);GO:0031514(motile cilium);GO:0032391(photoreceptor connecting cilium);GO:0032402(melanosome transport);GO:0032465(regulation of cytokinesis);GO:0033210(leptin-mediated signaling pathway);GO:0033365(protein localization to organelle);GO:0034260(negative regulation of GTPase activity);GO:0034451(centriolar satellite);GO:0034452(dynactin binding);GO:0034454(microtubule anchoring at centrosome);GO:0034464(BBSome);GO:0035176(social behavior);GO:0035845(photoreceptor cell outer segment organization);GO:0035869(ciliary transition zone);GO:0036064(ciliary basal body);GO:0038108(negative regulation of appetite by leptin-mediated signaling pathway);GO:0040018(positive regulation of multicellular organism growth);GO:0042995(cell projection);GO:0043014(alpha-tubulin binding);GO:0044321(response to leptin);GO:0045444(fat cell differentiation);GO:0045494(photoreceptor cell maintenance);GO:0045724(positive regulation of cilium assembly);GO:0046548(retinal rod cell development);GO:0046907(intracellular transport);GO:0048487(beta-tubulin binding);GO:0048854(brain morphogenesis);GO:0050893(sensory processing);GO:0050896(response to stimulus);GO:0051457(maintenance of protein location in nucleus);GO:0051492(regulation of stress fiber assembly);GO:0060170(ciliary membrane);GO:0060271(cilium assembly);GO:0060296(regulation of cilium beat frequency involved in ciliary motility);GO:0060324(face development);GO:0060613(fat pad development);GO:0061512(protein localization to cilium);GO:0071539(protein localization to centrosome);GO:0097730(non-motile cilium);GO:1902855(regulation of non-motile cilium assembly);GO:1903546(protein localization to photoreceptor outer segment);GO:1905515(non-motile cilium assembly)","NA","NA","NA","Bardet-Biedl syndrome 4 [Source:HGNC Symbol;Acc:HGNC:969]",{"v":0.719839,"d":"0.72"},{"v":1.095487,"d":"1.10"},{"v":0.696525,"d":"0.70"},0,{"v":0.003088,"d":"0.00"},{"v":0.024673,"d":"0.02"},{"v":90.4812866971651,"d":"90.48"},{"v":6.4995475403338,"d":"6.50"},{"v":3.74428245764373e-5,"d":"0.00"},{"v":0.00498277588594128,"d":"0.00"},"up","yes"]
[131086,0,"chr21","-",44805617,44818051,"ENST00000397898",4,1779,"ENSG00000184900","SUMO3","GO:0000776(kinetochore);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0016605(PML body);GO:0016925(protein sumoylation);GO:0019899(enzyme binding);GO:0031386(protein tag);GO:0043392(negative regulation of DNA binding);GO:0044389(ubiquitin-like protein ligase binding)","03013(RNA transport);05418(Fluid shear stress and atherosclerosis)","K12160","NA","small ubiquitin-like modifier 3 [Source:HGNC Symbol;Acc:HGNC:11124]",{"v":0.001172,"d":"0.00"},{"v":0.001228,"d":"0.00"},{"v":0.041376,"d":"0.04"},{"v":14.689133,"d":"14.69"},{"v":16.431269,"d":"16.43"},0,{"v":0.00140666563368944,"d":"0.00"},{"v":-9.47350484588562,"d":"-9.47"},{"v":3.77337348048632e-5,"d":"0.00"},{"v":0.00500316272065942,"d":"0.01"},"down","yes"]
[127597,0,"chr20","-",47657406,47786616,"ENST00000484875",21,4238,"ENSG00000196562","SULF2","GO:0001822(kidney development);GO:0002063(chondrocyte development);GO:0003094(glomerular filtration);GO:0003824(catalytic activity);GO:0004065(arylsulfatase activity);GO:0005509(calcium ion binding);GO:0005539(glycosaminoglycan binding);GO:0005615(extracellular space);GO:0005783(endoplasmic reticulum);GO:0005794(Golgi apparatus);GO:0005795(Golgi stack);GO:0005886(plasma membrane);GO:0008449(N-acetylglucosamine-6-sulfatase activity);GO:0008484(sulfuric ester hydrolase activity);GO:0009611(response to wounding);GO:0009986(cell surface);GO:0010575(positive regulation of vascular endothelial growth factor production);GO:0014846(esophagus smooth muscle contraction);GO:0016787(hydrolase activity);GO:0030177(positive regulation of Wnt signaling pathway);GO:0030201(heparan sulfate proteoglycan metabolic process);GO:0032836(glomerular basement membrane development);GO:0035860(glial cell-derived neurotrophic factor receptor signaling pathway);GO:0040037(negative regulation of fibroblast growth factor receptor signaling pathway);GO:0046872(metal ion binding);GO:0048706(embryonic skeletal system development);GO:0051216(cartilage development);GO:0060348(bone development);GO:0060384(innervation);GO:0090263(positive regulation of canonical Wnt signaling pathway);GO:0097421(liver regeneration);GO:2000345(regulation of hepatocyte proliferation)","NA","K14607","EC:3.1.6.-","sulfatase 2 [Source:HGNC Symbol;Acc:HGNC:20392]",{"v":3.840673,"d":"3.84"},{"v":5.503563,"d":"5.50"},{"v":5.000168,"d":"5.00"},{"v":0.095473,"d":"0.10"},{"v":0.063962,"d":"0.06"},{"v":0.46046,"d":"0.46"},{"v":23.1400543640455,"d":"23.14"},{"v":4.53232034872977,"d":"4.53"},{"v":3.80753585760279e-5,"d":"0.00"},{"v":0.0050301010075167,"d":"0.01"},"up","yes"]
[128293,0,"chr20","+",59933764,59948680,"ENST00000358293",5,5152,"ENSG00000196227","FAM217B","GO:0005654(nucleoplasm);GO:0005829(cytosol)","NA","NA","NA","family with sequence similarity 217 member B [Source:HGNC Symbol;Acc:HGNC:16170]",{"v":0.412711,"d":"0.41"},{"v":0.441705,"d":"0.44"},{"v":0.009171,"d":"0.01"},0,0,0,"inf","inf",{"v":3.8966877778676e-5,"d":"0.00"},{"v":0.0051292270641279,"d":"0.01"},"up","yes"]
[59483,0,"chr14","-",92058552,92106621,"ENST00000393287",9,6770,"ENSG00000066427","ATXN3","GO:0000226(microtubule cytoskeleton organization);GO:0001012(RNA polymerase II regulatory region DNA binding);GO:0004407(histone deacetylase activity);GO:0004843(thiol-dependent ubiquitin-specific protease activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005730(nucleolus);GO:0005737(cytoplasm);GO:0005759(mitochondrial matrix);GO:0005789(endoplasmic reticulum membrane);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0006289(nucleotide-excision repair);GO:0006508(proteolysis);GO:0006511(ubiquitin-dependent protein catabolic process);GO:0006515(protein quality control for misfolded or incompletely synthesized proteins);GO:0007268(chemical synaptic transmission);GO:0007399(nervous system development);GO:0008233(peptidase activity);GO:0008234(cysteine-type peptidase activity);GO:0010810(regulation of cell-substrate adhesion);GO:0016363(nuclear matrix);GO:0016579(protein deubiquitination);GO:0016787(hydrolase activity);GO:0030036(actin cytoskeleton organization);GO:0031625(ubiquitin protein ligase binding);GO:0031966(mitochondrial membrane);GO:0034605(cellular response to heat);GO:0035520(monoubiquitinated protein deubiquitination);GO:0035640(exploration behavior);GO:0036459(thiol-dependent ubiquitinyl hydrolase activity);GO:0042405(nuclear inclusion body);GO:0043161(proteasome-mediated ubiquitin-dependent protein catabolic process);GO:0045104(intermediate filament cytoskeleton organization);GO:0051117(ATPase binding);GO:0061578(Lys63-specific deubiquitinase activity);GO:0070536(protein K63-linked deubiquitination);GO:0070932(histone H3 deacetylation);GO:0071108(protein K48-linked deubiquitination);GO:0071218(cellular response to misfolded protein);GO:1904294(positive regulation of ERAD pathway);GO:1904379(protein localization to cytosolic proteasome complex involved in ERAD pathway);GO:1990380(Lys48-specific deubiquitinase activity)","04141(Protein processing in endoplasmic reticulum)","K11863","EC:3.4.22.-","ataxin 3 [Source:HGNC Symbol;Acc:HGNC:7106]",{"v":0.72641,"d":"0.73"},{"v":0.515639,"d":"0.52"},0,0,0,0,"inf","inf",{"v":3.98341416444074e-5,"d":"0.00"},{"v":0.00522445619473401,"d":"0.01"},"up","yes"]
[145703,0,"chr3","-",155826533,155854416,"ENST00000468581",5,3558,"ENSG00000169359","SLC33A1","GO:0000139(Golgi membrane);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005887(integral component of plasma membrane);GO:0008521(acetyl-CoA transmembrane transporter activity);GO:0015295(solute:proton symporter activity);GO:0015876(acetyl-CoA transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0030509(BMP signaling pathway);GO:0055085(transmembrane transport);GO:0060395(SMAD protein signal transduction);GO:1902600(proton transmembrane transport)","00604(Glycosphingolipid biosynthesis - ganglio series)","NA","NA","solute carrier family 33 member 1 [Source:HGNC Symbol;Acc:HGNC:95]",0,0,0,0,{"v":0.629683,"d":"0.63"},{"v":2.325372,"d":"2.33"},"-inf","-inf",{"v":4.05427313210767e-5,"d":"0.00"},{"v":0.00528482205842255,"d":"0.01"},"down","yes"]
[94820,0,"chr18","+",50879228,50935270,"ENST00000639688",12,4344,"ENSG00000082212","ME2","GO:0003824(catalytic activity);GO:0004470(malic enzyme activity);GO:0004471(malate dehydrogenase (decarboxylating) (NAD+) activity);GO:0004473(malate dehydrogenase (decarboxylating) (NADP+) activity);GO:0005739(mitochondrion);GO:0005759(mitochondrial matrix);GO:0006090(pyruvate metabolic process);GO:0006099(tricarboxylic acid cycle);GO:0006108(malate metabolic process);GO:0008152(metabolic process);GO:0008948(oxaloacetate decarboxylase activity);GO:0009055(electron transfer activity);GO:0016491(oxidoreductase activity);GO:0022900(electron transport chain);GO:0046872(metal ion binding);GO:0051287(NAD binding);GO:0055114(oxidation-reduction process);GO:1902031(regulation of NADP metabolic process)","00620(Pyruvate metabolism)","K00027","EC:1.1.1.38","malic enzyme 2 [Source:HGNC Symbol;Acc:HGNC:6984]",0,0,0,0,{"v":1.240831,"d":"1.24"},{"v":0.70579,"d":"0.71"},"-inf","-inf",{"v":4.07088880294892e-5,"d":"0.00"},{"v":0.00528482205842255,"d":"0.01"},"down","yes"]
[19545,0,"chr10","+",18140958,18540763,"ENST00000282343",14,3160,"ENSG00000165995","CACNB2","GO:0005244(voltage-gated ion channel activity);GO:0005245(voltage-gated calcium channel activity);GO:0005262(calcium channel activity);GO:0005515(protein binding);GO:0005886(plasma membrane);GO:0005887(integral component of plasma membrane);GO:0005891(voltage-gated calcium channel complex);GO:0006811(ion transport);GO:0006816(calcium ion transport);GO:0007268(chemical synaptic transmission);GO:0007528(neuromuscular junction development);GO:0007601(visual perception);GO:0008331(high voltage-gated calcium channel activity);GO:0016020(membrane);GO:0034765(regulation of ion transmembrane transport);GO:0042383(sarcolemma);GO:0051015(actin filament binding);GO:0051928(positive regulation of calcium ion transport);GO:0061337(cardiac conduction);GO:0070509(calcium ion import);GO:0070588(calcium ion transmembrane transport);GO:0072659(protein localization to plasma membrane);GO:0086007(voltage-gated calcium channel activity involved in cardiac muscle cell action potential);GO:0086045(membrane depolarization during AV node cell action potential);GO:0086056(voltage-gated calcium channel activity involved in AV node cell action potential);GO:0086091(regulation of heart rate by cardiac conduction);GO:0098684(photoreceptor ribbon synapse);GO:0098793(presynapse);GO:0098912(membrane depolarization during atrial cardiac muscle cell action potential);GO:0099533(positive regulation of presynaptic cytosolic calcium concentration);GO:0099635(voltage-gated calcium channel activity involved in positive regulation of presynaptic cytosolic calcium levels);GO:0099703(induction of synaptic vesicle exocytosis by positive regulation of presynaptic cytosolic calcium ion concentration);GO:1901385(regulation of voltage-gated calcium channel activity);GO:1901843(positive regulation of high voltage-gated calcium channel activity);GO:1904879(positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel);GO:1990454(L-type voltage-gated calcium channel complex)","04010(MAPK signaling pathway);04260(Cardiac muscle contraction);04261(Adrenergic signaling in cardiomyocytes);04921(Oxytocin signaling pathway);05410(Hypertrophic cardiomyopathy (HCM));05412(Arrhythmogenic right ventricular cardiomyopathy (ARVC));05414(Dilated cardiomyopathy (DCM))","NA","NA","calcium voltage-gated channel auxiliary subunit beta 2 [Source:HGNC Symbol;Acc:HGNC:1402]",0,0,0,0,{"v":1.307171,"d":"1.31"},{"v":1.270979,"d":"1.27"},"-inf","-inf",{"v":4.07308058452605e-5,"d":"0.00"},{"v":0.00528482205842255,"d":"0.01"},"down","yes"]
[15563,0,"chr1","+",203798846,203854034,"ENST00000495527",17,8404,"ENSG00000058673","ZC3H11A","GO:0000346(transcription export complex);GO:0003723(RNA binding);GO:0003729(mRNA binding);GO:0005515(protein binding);GO:0005654(nucleoplasm);GO:0006405(RNA export from nucleus);GO:0006406(mRNA export from nucleus);GO:0016973(poly(A)+ mRNA export from nucleus);GO:0031124(mRNA 3'-end processing);GO:0046872(metal ion binding);GO:0051028(mRNA transport)","NA","K22415","NA","zinc finger CCCH-type containing 11A [Source:HGNC Symbol;Acc:HGNC:29093]",{"v":0.00516,"d":"0.01"},{"v":6.291821,"d":"6.29"},{"v":4.727921,"d":"4.73"},{"v":0.044946,"d":"0.04"},{"v":0.007506,"d":"0.01"},{"v":0.030005,"d":"0.03"},{"v":133.704864353542,"d":"133.70"},{"v":7.06290814324692,"d":"7.06"},{"v":4.10604558719416e-5,"d":"0.00"},{"v":0.00530863473960014,"d":"0.01"},"up","yes"]
[154573,0,"chr4","+",122170603,122362758,"ENST00000388738",84,15574,"ENSG00000138688","KIAA1109","GO:0001558(regulation of cell growth);GO:0005515(protein binding);GO:0005634(nucleus);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0030856(regulation of epithelial cell differentiation);GO:0048488(synaptic vesicle endocytosis);GO:0098793(presynapse)","NA","NA","NA","KIAA1109 [Source:HGNC Symbol;Acc:HGNC:26953]",0,0,0,{"v":0.266304,"d":"0.27"},{"v":0.22897,"d":"0.23"},0,"-inf","-inf",{"v":4.23380650891986e-5,"d":"0.00"},{"v":0.0054544039173425,"d":"0.01"},"down","yes"]
[82294,0,"chr17","+",18087948,18107969,"ENST00000225729",13,1900,"ENSG00000108591","DRG2","GO:0000166(nucleotide binding);GO:0002181(cytoplasmic translation);GO:0003723(RNA binding);GO:0003924(GTPase activity);GO:0005515(protein binding);GO:0005525(GTP binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0007165(signal transduction);GO:0016020(membrane);GO:0016787(hydrolase activity);GO:0043231(intracellular membrane-bounded organelle);GO:0046872(metal ion binding)","NA","K06944","NA","developmentally regulated GTP binding protein 2 [Source:HGNC Symbol;Acc:HGNC:3030]",{"v":3.359196,"d":"3.36"},{"v":5.306732,"d":"5.31"},{"v":4.584767,"d":"4.58"},{"v":0.254387,"d":"0.25"},{"v":0.145285,"d":"0.15"},{"v":0.142669,"d":"0.14"},{"v":24.4324050735607,"d":"24.43"},{"v":4.61072398128886,"d":"4.61"},{"v":4.30874570700768e-5,"d":"0.00"},{"v":0.0055313332698088,"d":"0.01"},"up","yes"]
[82300,0,"chr17","+",18087968,18107970,"ENST00000467099",12,2531,"ENSG00000108591","DRG2","GO:0000166(nucleotide binding);GO:0002181(cytoplasmic translation);GO:0003723(RNA binding);GO:0003924(GTPase activity);GO:0005515(protein binding);GO:0005525(GTP binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0007165(signal transduction);GO:0016020(membrane);GO:0016787(hydrolase activity);GO:0043231(intracellular membrane-bounded organelle);GO:0046872(metal ion binding)","NA","K06944","NA","developmentally regulated GTP binding protein 2 [Source:HGNC Symbol;Acc:HGNC:3030]",0,0,0,0,{"v":1.134968,"d":"1.13"},{"v":2.034177,"d":"2.03"},"-inf","-inf",{"v":4.33595306292584e-5,"d":"0.00"},{"v":0.00554666108366535,"d":"0.01"},"down","yes"]
[115258,0,"chr2","-",96593174,96638331,"ENST00000420155",21,5028,"ENSG00000114982","KANSL3","GO:0000123(histone acetyltransferase complex);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005730(nucleolus);GO:0006325(chromatin organization);GO:0043231(intracellular membrane-bounded organelle);GO:0043981(histone H4-K5 acetylation);GO:0043982(histone H4-K8 acetylation);GO:0043984(histone H4-K16 acetylation);GO:0043995(histone acetyltransferase activity (H4-K5 specific));GO:0043996(histone acetyltransferase activity (H4-K8 specific));GO:0044545(NSL complex);GO:0046972(histone acetyltransferase activity (H4-K16 specific))","NA","K16719","NA","KAT8 regulatory NSL complex subunit 3 [Source:HGNC Symbol;Acc:HGNC:25473]",{"v":8.782639,"d":"8.78"},{"v":1.332718,"d":"1.33"},{"v":0.029466,"d":"0.03"},0,{"v":0.022018,"d":"0.02"},{"v":0.019301,"d":"0.02"},{"v":245.524407657494,"d":"245.52"},{"v":7.93972264020516,"d":"7.94"},{"v":4.36584898037969e-5,"d":"0.00"},{"v":0.00556530854235769,"d":"0.01"},"up","yes"]
[87291,0,"chr17","+",48831035,48863196,"ENST00000508679",12,1396,"ENSG00000136436","CALCOCO2","GO:0000421(autophagosome membrane);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005776(autophagosome);GO:0005829(cytosol);GO:0005856(cytoskeleton);GO:0006914(autophagy);GO:0016020(membrane);GO:0016032(viral process);GO:0031410(cytoplasmic vesicle);GO:0034341(response to interferon-gamma);GO:0042803(protein homodimerization activity);GO:0043231(intracellular membrane-bounded organelle);GO:0048471(perinuclear region of cytoplasm);GO:0098792(xenophagy);GO:1901098(positive regulation of autophagosome maturation)","04137(Mitophagy - animal)","K21348","NA","calcium binding and coiled-coil domain 2 [Source:HGNC Symbol;Acc:HGNC:29912]",{"v":1.344412,"d":"1.34"},0,{"v":6.050117,"d":"6.05"},0,0,0,"inf","inf",{"v":4.3969251835238e-5,"d":"0.00"},{"v":0.00558532489221746,"d":"0.01"},"up","yes"]
[87596,0,"chr17","-",50190909,50194058,"ENST00000476387",9,600,"ENSG00000108821","COL1A1","GO:0001501(skeletal system development);GO:0001503(ossification);GO:0001568(blood vessel development);GO:0001649(osteoblast differentiation);GO:0001957(intramembranous ossification);GO:0001958(endochondral ossification);GO:0002020(protease binding);GO:0005201(extracellular matrix structural constituent);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0005581(collagen trimer);GO:0005584(collagen type I trimer);GO:0005615(extracellular space);GO:0005737(cytoplasm);GO:0005783(endoplasmic reticulum);GO:0005788(endoplasmic reticulum lumen);GO:0005794(Golgi apparatus);GO:0007584(response to nutrient);GO:0007596(blood coagulation);GO:0007601(visual perception);GO:0007605(sensory perception of sound);GO:0009612(response to mechanical stimulus);GO:0010718(positive regulation of epithelial to mesenchymal transition);GO:0010812(negative regulation of cell-substrate adhesion);GO:0015031(protein transport);GO:0030020(extracellular matrix structural constituent conferring tensile strength);GO:0030141(secretory granule);GO:0030168(platelet activation);GO:0030198(extracellular matrix organization);GO:0030199(collagen fibril organization);GO:0030335(positive regulation of cell migration);GO:0031012(extracellular matrix);GO:0031667(response to nutrient levels);GO:0031960(response to corticosteroid);GO:0032355(response to estradiol);GO:0032964(collagen biosynthetic process);GO:0034504(protein localization to nucleus);GO:0034505(tooth mineralization);GO:0038063(collagen-activated tyrosine kinase receptor signaling pathway);GO:0042060(wound healing);GO:0042493(response to drug);GO:0042542(response to hydrogen peroxide);GO:0042802(identical protein binding);GO:0043434(response to peptide hormone);GO:0043588(skin development);GO:0043589(skin morphogenesis);GO:0044344(cellular response to fibroblast growth factor stimulus);GO:0044691(tooth eruption);GO:0045893(positive regulation of transcription, DNA-templated);GO:0046872(metal ion binding);GO:0048407(platelet-derived growth factor binding);GO:0048545(response to steroid hormone);GO:0048705(skeletal system morphogenesis);GO:0048706(embryonic skeletal system development);GO:0050776(regulation of immune response);GO:0050900(leukocyte migration);GO:0051591(response to cAMP);GO:0055093(response to hyperoxia);GO:0060325(face morphogenesis);GO:0060346(bone trabecula formation);GO:0060351(cartilage development involved in endochondral bone morphogenesis);GO:0062023(collagen-containing extracellular matrix);GO:0070208(protein heterotrimerization);GO:0071230(cellular response to amino acid stimulus);GO:0071260(cellular response to mechanical stimulus);GO:0071300(cellular response to retinoic acid);GO:0071306(cellular response to vitamin E);GO:0071356(cellular response to tumor necrosis factor);GO:0071364(cellular response to epidermal growth factor stimulus);GO:0071560(cellular response to transforming growth factor beta stimulus);GO:0090263(positive regulation of canonical Wnt signaling pathway);GO:1902617(response to fluoride);GO:1902618(cellular response to fluoride)","04151(PI3K-Akt signaling pathway);04510(Focal adhesion);04512(ECM-receptor interaction);04611(Platelet activation);04926(Relaxin signaling pathway);04933(AGE-RAGE signaling pathway in diabetic complications);04974(Protein digestion and absorption);05146(Amoebiasis);05165(Human papillomavirus infection)","K06236","NA","collagen type I alpha 1 chain [Source:HGNC Symbol;Acc:HGNC:2197]",{"v":1.207473,"d":"1.21"},{"v":1.876535,"d":"1.88"},{"v":1.446505,"d":"1.45"},{"v":1.450434,"d":"1.45"},{"v":1586.805542,"d":"1586.81"},{"v":1.013852,"d":"1.01"},{"v":0.00285068836026503,"d":"0.00"},{"v":-8.45447395344469,"d":"-8.45"},{"v":4.43899886729478e-5,"d":"0.00"},{"v":0.00561912295640485,"d":"0.01"},"down","yes"]
[18914,0,"chr10","+",6202900,6235519,"ENST00000360521",16,4524,"ENSG00000170525","PFKFB3","GO:0000166(nucleotide binding);GO:0003824(catalytic activity);GO:0003873(6-phosphofructo-2-kinase activity);GO:0004331(fructose-2,6-bisphosphate 2-phosphatase activity);GO:0005524(ATP binding);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0006000(fructose metabolic process);GO:0006003(fructose 2,6-bisphosphate metabolic process);GO:0007420(brain development);GO:0008152(metabolic process);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0016311(dephosphorylation);GO:0016740(transferase activity);GO:0016787(hydrolase activity);GO:0045821(positive regulation of glycolytic process);GO:0046835(carbohydrate phosphorylation)","00051(Fructose and mannose metabolism);04066(HIF-1 signaling pathway);04152(AMPK signaling pathway)","K01103","3.1.3.46;EC:2.7.1.105","6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 [Source:HGNC Symbol;Acc:HGNC:8874]",{"v":0.686876,"d":"0.69"},{"v":0.001337,"d":"0.00"},{"v":1.384851,"d":"1.38"},{"v":0.002369,"d":"0.00"},{"v":0.001565,"d":"0.00"},0,{"v":526.960854092527,"d":"526.96"},{"v":9.04155198331803,"d":"9.04"},{"v":4.66019215326706e-5,"d":"0.00"},{"v":0.00587863822667335,"d":"0.01"},"up","yes"]
[63426,0,"chr15","+",43185405,43195160,"ENST00000569745",9,1356,"ENSG00000166946","CCNDBP1","GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0007049(cell cycle);GO:0051726(regulation of cell cycle)","NA","K21626","NA","cyclin D1 binding protein 1 [Source:HGNC Symbol;Acc:HGNC:1587]",0,0,0,{"v":0.983504,"d":"0.98"},{"v":1.747172,"d":"1.75"},{"v":0.062599,"d":"0.06"},"-inf","-inf",{"v":4.73305522945436e-5,"d":"0.00"},{"v":0.00592270082818317,"d":"0.01"},"down","yes"]
[149108,0,"chr4","+",1347706,1386244,"ENST00000507531",14,2597,"ENSG00000163945","UVSSA","GO:0000993(RNA polymerase II complex binding);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005694(chromosome);GO:0005737(cytoplasm);GO:0005783(endoplasmic reticulum);GO:0005886(plasma membrane);GO:0006281(DNA repair);GO:0006283(transcription-coupled nucleotide-excision repair);GO:0006469(negative regulation of protein kinase activity);GO:0006974(cellular response to DNA damage stimulus);GO:0009411(response to UV);GO:0016020(membrane);GO:0016567(protein ubiquitination);GO:0033147(negative regulation of intracellular estrogen receptor signaling pathway);GO:0043627(response to estrogen);GO:0051493(regulation of cytoskeleton organization)","NA","NA","NA","UV stimulated scaffold protein A [Source:HGNC Symbol;Acc:HGNC:29304]",0,0,0,{"v":1.388067,"d":"1.39"},0,{"v":1.236221,"d":"1.24"},"-inf","-inf",{"v":4.75040327285823e-5,"d":"0.00"},{"v":0.00592270082818317,"d":"0.01"},"down","yes"]
[89451,0,"chr17","+",68248504,68257090,"ENST00000577866",8,1492,"ENSG00000196704","AMZ2","GO:0005575(cellular_component);GO:0006508(proteolysis);GO:0008233(peptidase activity);GO:0008237(metallopeptidase activity);GO:0008270(zinc ion binding);GO:0016787(hydrolase activity);GO:0046872(metal ion binding)","NA","K06974","EC:3.4.-.-","archaelysin family metallopeptidase 2 [Source:HGNC Symbol;Acc:HGNC:28041]",{"v":11.548584,"d":"11.55"},{"v":0.641109,"d":"0.64"},0,0,0,0,"inf","inf",{"v":4.75810212115478e-5,"d":"0.00"},{"v":0.00592270082818317,"d":"0.01"},"up","yes"]
[207472,0,"chrX","-",154506171,154516116,"ENST00000369643",10,1521,"ENSG00000071889","FAM3A","GO:0003674(molecular_function);GO:0005515(protein binding);GO:0005575(cellular_component);GO:0005576(extracellular region);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0019732(antifungal humoral response);GO:0045721(negative regulation of gluconeogenesis);GO:0046890(regulation of lipid biosynthetic process);GO:0061844(antimicrobial humoral immune response mediated by antimicrobial peptide);GO:1905035(negative regulation of antifungal innate immune response)","NA","NA","NA","family with sequence similarity 3 member A [Source:HGNC Symbol;Acc:HGNC:13749]",0,0,0,{"v":2.452194,"d":"2.45"},{"v":2.324388,"d":"2.32"},0,"-inf","-inf",{"v":4.7742282590079e-5,"d":"0.00"},{"v":0.00592270082818317,"d":"0.01"},"down","yes"]
[119493,0,"chr2","-",175074505,175168169,"ENST00000456655",14,1861,"ENSG00000115966","ATF2","GO:0000122(negative regulation of transcription by RNA polymerase II);GO:0000977(RNA polymerase II regulatory region sequence-specific DNA binding);GO:0000980(RNA polymerase II distal enhancer sequence-specific DNA binding);GO:0000981(DNA-binding transcription factor activity, RNA polymerase II-specific);GO:0001102(RNA polymerase II activating transcription factor binding);GO:0001158(enhancer sequence-specific DNA binding);GO:0001228(DNA-binding transcription activator activity, RNA polymerase II-specific);GO:0003151(outflow tract morphogenesis);GO:0003676(nucleic acid binding);GO:0003677(DNA binding);GO:0003682(chromatin binding);GO:0003700(DNA-binding transcription factor activity);GO:0004402(histone acetyltransferase activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0005739(mitochondrion);GO:0005741(mitochondrial outer membrane);GO:0006355(regulation of transcription, DNA-templated);GO:0006357(regulation of transcription by RNA polymerase II);GO:0006970(response to osmotic stress);GO:0006974(cellular response to DNA damage stimulus);GO:0008134(transcription factor binding);GO:0008140(cAMP response element binding protein binding);GO:0009414(response to water deprivation);GO:0010628(positive regulation of gene expression);GO:0016020(membrane);GO:0016525(negative regulation of angiogenesis);GO:0016573(histone acetylation);GO:0016740(transferase activity);GO:0019901(protein kinase binding);GO:0031573(intra-S DNA damage checkpoint);GO:0032915(positive regulation of transforming growth factor beta2 production);GO:0035497(cAMP response element binding);GO:0035861(site of double-strand break);GO:0043525(positive regulation of neuron apoptotic process);GO:0043565(sequence-specific DNA binding);GO:0045444(fat cell differentiation);GO:0045944(positive regulation of transcription by RNA polymerase II);GO:0046872(metal ion binding);GO:0046982(protein heterodimerization activity);GO:0050680(negative regulation of epithelial cell proliferation);GO:0051090(regulation of DNA-binding transcription factor activity);GO:0051091(positive regulation of DNA-binding transcription factor activity);GO:0060612(adipose tissue development);GO:0097186(amelogenesis);GO:0110024(positive regulation of cardiac muscle myoblast proliferation);GO:1902110(positive regulation of mitochondrial membrane permeability involved in apoptotic process)","04010(MAPK signaling pathway);04022(cGMP-PKG signaling pathway);04151(PI3K-Akt signaling pathway);04211(Longevity regulating pathway);04261(Adrenergic signaling in cardiomyocytes);04668(TNF signaling pathway);04714(Thermogenesis);04728(Dopaminergic synapse);04911(Insulin secretion);04915(Estrogen signaling pathway);04918(Thyroid hormone synthesis);04922(Glucagon signaling pathway);04925(Aldosterone synthesis and secretion);04926(Relaxin signaling pathway);04927(Cortisol synthesis and secretion);04928(Parathyroid hormone synthesis, secretion and action);04934(Cushing syndrome);05030(Cocaine addiction);05031(Amphetamine addiction);05034(Alcoholism);05161(Hepatitis B);05163(Human cytomegalovirus infection);05164(Influenza A);05166(Human T-cell leukemia virus 1 infection);05203(Viral carcinogenesis)","NA","NA","activating transcription factor 2 [Source:HGNC Symbol;Acc:HGNC:784]",{"v":3.850239,"d":"3.85"},{"v":0.999714,"d":"1.00"},0,0,0,0,"inf","inf",{"v":4.77663457929443e-5,"d":"0.00"},{"v":0.00592270082818317,"d":"0.01"},"up","yes"]
[112353,0,"chr2","-",53670319,53787009,"ENST00000394717",9,1734,"ENSG00000115239","ASB3","GO:0005515(protein binding);GO:0005829(cytosol);GO:0016567(protein ubiquitination);GO:0035556(intracellular signal transduction);GO:0043687(post-translational protein modification)","NA","K10325","NA","ankyrin repeat and SOCS box containing 3 [Source:HGNC Symbol;Acc:HGNC:16013]",{"v":4.601902,"d":"4.60"},{"v":2.029714,"d":"2.03"},{"v":3.448099,"d":"3.45"},{"v":0.111869,"d":"0.11"},0,{"v":0.040317,"d":"0.04"},{"v":66.2328663609005,"d":"66.23"},{"v":6.04947539000771,"d":"6.05"},{"v":4.87032104580842e-5,"d":"0.00"},{"v":0.00601832529232041,"d":"0.01"},"up","yes"]
[94818,0,"chr18","+",50879166,50947874,"ENST00000639115",15,2524,"ENSG00000082212","ME2","GO:0003824(catalytic activity);GO:0004470(malic enzyme activity);GO:0004471(malate dehydrogenase (decarboxylating) (NAD+) activity);GO:0004473(malate dehydrogenase (decarboxylating) (NADP+) activity);GO:0005739(mitochondrion);GO:0005759(mitochondrial matrix);GO:0006090(pyruvate metabolic process);GO:0006099(tricarboxylic acid cycle);GO:0006108(malate metabolic process);GO:0008152(metabolic process);GO:0008948(oxaloacetate decarboxylase activity);GO:0009055(electron transfer activity);GO:0016491(oxidoreductase activity);GO:0022900(electron transport chain);GO:0046872(metal ion binding);GO:0051287(NAD binding);GO:0055114(oxidation-reduction process);GO:1902031(regulation of NADP metabolic process)","00620(Pyruvate metabolism)","K00027","EC:1.1.1.38","malic enzyme 2 [Source:HGNC Symbol;Acc:HGNC:6984]",0,0,0,0,{"v":1.304051,"d":"1.30"},{"v":1.54245,"d":"1.54"},"-inf","-inf",{"v":4.903834977292e-5,"d":"0.00"},{"v":0.0060391974483057,"d":"0.01"},"down","yes"]
[42628,0,"chr12","+",49741557,49764737,"ENST00000552699",11,2964,"ENSG00000139644","TMBIM6","GO:0005515(protein binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005887(integral component of plasma membrane);GO:0006914(autophagy);GO:0006915(apoptotic process);GO:0006986(response to unfolded protein);GO:0010523(negative regulation of calcium ion transport into cytosol);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0019899(enzyme binding);GO:0031625(ubiquitin protein ligase binding);GO:0031966(mitochondrial membrane);GO:0032091(negative regulation of protein binding);GO:0032469(endoplasmic reticulum calcium ion homeostasis);GO:0033119(negative regulation of RNA splicing);GO:0034620(cellular response to unfolded protein);GO:0034976(response to endoplasmic reticulum stress);GO:0043066(negative regulation of apoptotic process);GO:0051025(negative regulation of immunoglobulin secretion);GO:0060698(endoribonuclease inhibitor activity);GO:0060702(negative regulation of endoribonuclease activity);GO:0070059(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress);GO:1902065(response to L-glutamate);GO:1902236(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway);GO:1903298(negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway);GO:1990441(negative regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress);GO:2001234(negative regulation of apoptotic signaling pathway)","NA","K21889","NA","transmembrane BAX inhibitor motif containing 6 [Source:HGNC Symbol;Acc:HGNC:11723]",0,0,0,0,{"v":1.279983,"d":"1.28"},{"v":1.155413,"d":"1.16"},"-inf","-inf",{"v":4.92978959030826e-5,"d":"0.00"},{"v":0.0060407058022224,"d":"0.01"},"down","yes"]
[32925,0,"chr11","-",66848520,66958383,"ENST00000393958",22,4017,"ENSG00000173599","PC","GO:0000166(nucleotide binding);GO:0003824(catalytic activity);GO:0004736(pyruvate carboxylase activity);GO:0005515(protein binding);GO:0005524(ATP binding);GO:0005737(cytoplasm);GO:0005739(mitochondrion);GO:0005759(mitochondrial matrix);GO:0005829(cytosol);GO:0006090(pyruvate metabolic process);GO:0006094(gluconeogenesis);GO:0006629(lipid metabolic process);GO:0006768(biotin metabolic process);GO:0008152(metabolic process);GO:0009374(biotin binding);GO:0010629(negative regulation of gene expression);GO:0016874(ligase activity);GO:0019074(viral RNA genome packaging);GO:0042802(identical protein binding);GO:0044791(positive regulation by host of viral release from host cell);GO:0044794(positive regulation by host of viral process);GO:0046872(metal ion binding)","00020(Citrate cycle (TCA cycle));00620(Pyruvate metabolism)","K01958","EC:6.4.1.1","pyruvate carboxylase [Source:HGNC Symbol;Acc:HGNC:8636]",{"v":3.282814,"d":"3.28"},{"v":14.26352,"d":"14.26"},{"v":1.019225,"d":"1.02"},{"v":0.297163,"d":"0.30"},{"v":0.116564,"d":"0.12"},{"v":0.285623,"d":"0.29"},{"v":26.546877815114,"d":"26.55"},{"v":4.73047029017213,"d":"4.73"},{"v":4.93831440478958e-5,"d":"0.00"},{"v":0.0060407058022224,"d":"0.01"},"up","yes"]
[106348,0,"chr19","+",49453236,49470585,"ENST00000455361",16,2470,"ENSG00000161618","ALDH16A1","GO:0016020(membrane);GO:0016491(oxidoreductase activity);GO:0016620(oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor);GO:0055114(oxidation-reduction process)","NA","NA","NA","aldehyde dehydrogenase 16 family member A1 [Source:HGNC Symbol;Acc:HGNC:28114]",0,0,0,{"v":0.86918,"d":"0.87"},0,{"v":2.005622,"d":"2.01"},"-inf","-inf",{"v":4.96728551534491e-5,"d":"0.00"},{"v":0.00605575445545236,"d":"0.01"},"down","yes"]
[43894,0,"chr12","-",55684568,55707701,"ENST00000553804",25,3935,"ENSG00000135424","ITGA7","GO:0005515(protein binding);GO:0005886(plasma membrane);GO:0007155(cell adhesion);GO:0007160(cell-matrix adhesion);GO:0007229(integrin-mediated signaling pathway);GO:0007517(muscle organ development);GO:0008305(integrin complex);GO:0008360(regulation of cell shape);GO:0009986(cell surface);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0030198(extracellular matrix organization);GO:0034113(heterotypic cell-cell adhesion);GO:0035987(endodermal cell differentiation);GO:0046872(metal ion binding)","04151(PI3K-Akt signaling pathway);04510(Focal adhesion);04512(ECM-receptor interaction);04810(Regulation of actin cytoskeleton);05165(Human papillomavirus infection);05410(Hypertrophic cardiomyopathy (HCM));05412(Arrhythmogenic right ventricular cardiomyopathy (ARVC));05414(Dilated cardiomyopathy (DCM))","K06583","NA","integrin subunit alpha 7 [Source:HGNC Symbol;Acc:HGNC:6143]",{"v":0.028949,"d":"0.03"},{"v":0.037997,"d":"0.04"},{"v":0.067095,"d":"0.07"},{"v":0.578049,"d":"0.58"},{"v":1.567079,"d":"1.57"},{"v":1.985735,"d":"1.99"},{"v":0.0324486675060393,"d":"0.03"},{"v":-4.94569695413581,"d":"-4.95"},{"v":5.00247103008747e-5,"d":"0.00"},{"v":0.00605827750335025,"d":"0.01"},"down","yes"]
[140540,0,"chr3","+",51975050,51989183,"ENST00000463721",17,1836,"ENSG00000114786","ABHD14A-ACY1","GO:0004046(aminoacylase activity);GO:0005737(cytoplasm);GO:0006508(proteolysis);GO:0006520(cellular amino acid metabolic process);GO:0008237(metallopeptidase activity);GO:0016787(hydrolase activity)","00220(Arginine biosynthesis)","K14677","EC:3.5.1.14","ABHD14A-ACY1 readthrough [Source:HGNC Symbol;Acc:HGNC:38856]",0,0,0,{"v":0.173081,"d":"0.17"},{"v":0.496053,"d":"0.50"},{"v":0.743567,"d":"0.74"},"-inf","-inf",{"v":5.0027064437244e-5,"d":"0.00"},{"v":0.00605827750335025,"d":"0.01"},"down","yes"]
[43727,0,"chr12","+",54325144,54350879,"ENST00000549116",7,736,"ENSG00000111481","COPZ1","GO:0000139(Golgi membrane);GO:0005737(cytoplasm);GO:0005789(endoplasmic reticulum membrane);GO:0005794(Golgi apparatus);GO:0005829(cytosol);GO:0006886(intracellular protein transport);GO:0006888(endoplasmic reticulum to Golgi vesicle-mediated transport);GO:0006890(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum);GO:0006891(intra-Golgi vesicle-mediated transport);GO:0015031(protein transport);GO:0016020(membrane);GO:0016192(vesicle-mediated transport);GO:0030117(membrane coat);GO:0030126(COPI vesicle coat);GO:0030133(transport vesicle);GO:0030663(COPI-coated vesicle membrane);GO:0031410(cytoplasmic vesicle);GO:1901998(toxin transport)","NA","K20472","NA","coatomer protein complex subunit zeta 1 [Source:HGNC Symbol;Acc:HGNC:2243]",0,0,0,{"v":1.343503,"d":"1.34"},0,{"v":15.846539,"d":"15.85"},"-inf","-inf",{"v":5.16743701426077e-5,"d":"0.00"},{"v":0.00623697630325892,"d":"0.01"},"down","yes"]
[174364,0,"chr6","-",137197497,137219244,"ENST00000644894",7,2492,"ENSG00000027697","IFNGR1","GO:0004896(cytokine receptor activity);GO:0004906(interferon-gamma receptor activity);GO:0005515(protein binding);GO:0005886(plasma membrane);GO:0005887(integral component of plasma membrane);GO:0007165(signal transduction);GO:0009615(response to virus);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0019221(cytokine-mediated signaling pathway);GO:0019955(cytokine binding);GO:0060333(interferon-gamma-mediated signaling pathway);GO:0060334(regulation of interferon-gamma-mediated signaling pathway)","04060(Cytokine-cytokine receptor interaction);04066(HIF-1 signaling pathway);04217(Necroptosis);04380(Osteoclast differentiation);04630(Jak-STAT signaling pathway);04650(Natural killer cell mediated cytotoxicity);04658(Th1 and Th2 cell differentiation);04659(Th17 cell differentiation);05132(Salmonella infection);05140(Leishmaniasis);05142(Chagas disease (American trypanosomiasis));05145(Toxoplasmosis);05152(Tuberculosis);05164(Influenza A);05167(Kaposi sarcoma-associated herpesvirus infection);05168(Herpes simplex virus 1 infection);05200(Pathways in cancer);05321(Inflammatory bowel disease (IBD))","K05132","NA","interferon gamma receptor 1 [Source:HGNC Symbol;Acc:HGNC:5439]",{"v":7.46399,"d":"7.46"},{"v":6.278606,"d":"6.28"},{"v":4.240175,"d":"4.24"},{"v":39.774967,"d":"39.77"},{"v":44.430111,"d":"44.43"},{"v":41.032433,"d":"41.03"},{"v":0.143589335626448,"d":"0.14"},{"v":-2.79997949064395,"d":"-2.80"},{"v":5.2211701781666e-5,"d":"0.00"},{"v":0.00626444601808253,"d":"0.01"},"down","yes"]
[204187,0,"chrX","+",71910818,72153286,"ENST00000633930",8,13660,"ENSG00000204131","NHSL2","GO:0030154(cell differentiation)","NA","NA","NA","NHS like 2 [Source:HGNC Symbol;Acc:HGNC:33737]",{"v":0.040181,"d":"0.04"},{"v":0.022082,"d":"0.02"},{"v":0.024486,"d":"0.02"},{"v":2.105468,"d":"2.11"},{"v":2.201123,"d":"2.20"},{"v":0.027334,"d":"0.03"},{"v":0.0200162670096968,"d":"0.02"},{"v":-5.64268325000467,"d":"-5.64"},{"v":5.22468247585743e-5,"d":"0.00"},{"v":0.00626444601808253,"d":"0.01"},"down","yes"]
[101035,0,"chr19","-",18531762,18543524,"ENST00000222308",9,1710,"ENSG00000105701","FKBP8","GO:0000413(protein peptidyl-prolyl isomerization);GO:0001708(cell fate specification);GO:0001933(negative regulation of protein phosphorylation);GO:0003755(peptidyl-prolyl cis-trans isomerase activity);GO:0005515(protein binding);GO:0005739(mitochondrion);GO:0005740(mitochondrial envelope);GO:0005783(endoplasmic reticulum);GO:0005829(cytosol);GO:0006915(apoptotic process);GO:0007224(smoothened signaling pathway);GO:0009953(dorsal/ventral pattern formation);GO:0010468(regulation of gene expression);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016032(viral process);GO:0016853(isomerase activity);GO:0021904(dorsal/ventral neural tube patterning);GO:0021915(neural tube development);GO:0030176(integral component of endoplasmic reticulum membrane);GO:0030510(regulation of BMP signaling pathway);GO:0030513(positive regulation of BMP signaling pathway);GO:0031966(mitochondrial membrane);GO:0032991(protein-containing complex);GO:0035264(multicellular organism growth);GO:0035556(intracellular signal transduction);GO:0042802(identical protein binding);GO:0043010(camera-type eye development);GO:0043066(negative regulation of apoptotic process);GO:0046872(metal ion binding);GO:0097718(disordered domain specific binding)","NA","K09574","EC:5.2.1.8","FKBP prolyl isomerase 8 [Source:HGNC Symbol;Acc:HGNC:3724]",{"v":3.445059,"d":"3.45"},{"v":0.79017,"d":"0.79"},{"v":2.778925,"d":"2.78"},{"v":38.258221,"d":"38.26"},{"v":8.515101,"d":"8.52"},{"v":51.20956,"d":"51.21"},{"v":0.071585504088357,"d":"0.07"},{"v":-3.80418871537367,"d":"-3.80"},{"v":5.24467908769904e-5,"d":"0.00"},{"v":0.00626773655447717,"d":"0.01"},"down","yes"]
[142845,0,"chr3","+",112562072,112584156,"ENST00000261034",8,2444,"ENSG00000138459","SLC35A5","GO:0000139(Golgi membrane);GO:0005794(Golgi apparatus);GO:0008643(carbohydrate transport);GO:0015136(sialic acid transmembrane transporter activity);GO:0015165(pyrimidine nucleotide-sugar transmembrane transporter activity);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0030173(integral component of Golgi membrane);GO:0090481(pyrimidine nucleotide-sugar transmembrane transport)","NA","K15274","NA","solute carrier family 35 member A5 [Source:HGNC Symbol;Acc:HGNC:20792]",{"v":2.031336,"d":"2.03"},0,{"v":0.967403,"d":"0.97"},0,0,0,"inf","inf",{"v":5.35098508800791e-5,"d":"0.00"},{"v":0.00637381272942057,"d":"0.01"},"up","yes"]
[193869,0,"chr8","-",144423601,144428563,"ENST00000377348",9,1097,"ENSG00000160948","VPS28","GO:0000813(ESCRT I complex);GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0005768(endosome);GO:0005769(early endosome);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0010008(endosome membrane);GO:0015031(protein transport);GO:0016020(membrane);GO:0016197(endosomal transport);GO:0016236(macroautophagy);GO:0019058(viral life cycle);GO:0031397(negative regulation of protein ubiquitination);GO:0031902(late endosome membrane);GO:0032509(endosome transport via multivesicular body sorting pathway);GO:0036258(multivesicular body assembly);GO:0039702(viral budding via host ESCRT complex);GO:0043130(ubiquitin binding);GO:0043162(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway);GO:0043328(protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway);GO:0043657(host cell);GO:0044877(protein-containing complex binding);GO:0045732(positive regulation of protein catabolic process);GO:0070062(extracellular exosome);GO:0075733(intracellular transport of virus);GO:2000397(positive regulation of ubiquitin-dependent endocytosis)","04144(Endocytosis)","K12184","NA","VPS28, ESCRT-I subunit [Source:HGNC Symbol;Acc:HGNC:18178]",{"v":6.736398,"d":"6.74"},{"v":3.006776,"d":"3.01"},{"v":2.322838,"d":"2.32"},{"v":0.082692,"d":"0.08"},{"v":0.117465,"d":"0.12"},{"v":0.177928,"d":"0.18"},{"v":31.9134903526985,"d":"31.91"},{"v":4.99609449852665,"d":"5.00"},{"v":5.37011681288281e-5,"d":"0.00"},{"v":0.00637569751019714,"d":"0.01"},"up","yes"]
[149589,0,"chr4","-",5562439,5709548,"ENST00000310917",22,4828,"ENSG00000173040","EVC2","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005856(cytoskeleton);GO:0005886(plasma membrane);GO:0005929(cilium);GO:0007224(smoothened signaling pathway);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0042995(cell projection);GO:0060170(ciliary membrane);GO:0098797(plasma membrane protein complex)","04340(Hedgehog signaling pathway)","K19608","NA","EvC ciliary complex subunit 2 [Source:HGNC Symbol;Acc:HGNC:19747]",0,0,0,{"v":1.165542,"d":"1.17"},{"v":0.387435,"d":"0.39"},0,"-inf","-inf",{"v":5.42565467461774e-5,"d":"0.00"},{"v":0.00642065258400204,"d":"0.01"},"down","yes"]
[20737,0,"chr10","-",45825594,45847473,"ENST00000448048",7,2439,"ENSG00000188234","AGAP4","GO:0005096(GTPase activator activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0043547(positive regulation of GTPase activity);GO:0046872(metal ion binding)","NA","NA","NA","ArfGAP with GTPase domain, ankyrin repeat and PH domain 4 [Source:HGNC Symbol;Acc:HGNC:23459]",{"v":1.518059,"d":"1.52"},0,{"v":1.317096,"d":"1.32"},0,0,0,"inf","inf",{"v":5.47064697663887e-5,"d":"0.00"},{"v":0.00644493630626463,"d":"0.01"},"up","yes"]
[140396,0,"chr3","-",50558811,50567676,"ENST00000441239",5,1490,"ENSG00000088543","C3orf18","GO:0016020(membrane);GO:0016021(integral component of membrane)","NA","NA","NA","chromosome 3 open reading frame 18 [Source:HGNC Symbol;Acc:HGNC:24837]",0,0,{"v":0.012441,"d":"0.01"},{"v":2.25071,"d":"2.25"},{"v":0.789658,"d":"0.79"},{"v":0.27707,"d":"0.28"},{"v":0.00375018312324149,"d":"0.00"},{"v":-8.05882323984238,"d":"-8.06"},{"v":5.487929057739e-5,"d":"0.00"},{"v":0.00644493630626463,"d":"0.01"},"down","yes"]
[9670,0,"chr1","+",113390972,113685923,"ENST00000369615",22,6508,"ENSG00000081026","MAGI3","GO:0000166(nucleotide binding);GO:0004385(guanylate kinase activity);GO:0005515(protein binding);GO:0005524(ATP binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005886(plasma membrane);GO:0005911(cell-cell junction);GO:0005923(bicellular tight junction);GO:0006915(apoptotic process);GO:0007165(signal transduction);GO:0016020(membrane);GO:0016032(viral process);GO:0030054(cell junction);GO:0032947(protein-containing complex scaffold activity);GO:0035556(intracellular signal transduction);GO:0046037(GMP metabolic process);GO:0046328(regulation of JNK cascade);GO:0046710(GDP metabolic process)","04015(Rap1 signaling pathway)","K06112","NA","membrane associated guanylate kinase, WW and PDZ domain containing 3 [Source:HGNC Symbol;Acc:HGNC:29647]",0,0,0,0,{"v":0.760054,"d":"0.76"},{"v":0.349113,"d":"0.35"},"-inf","-inf",{"v":5.49939514159657e-5,"d":"0.00"},{"v":0.00644493630626463,"d":"0.01"},"down","yes"]
[195182,0,"chr9","-",33255026,33264571,"ENST00000379704",7,1128,"ENSG00000107262","BAG1","GO:0000774(adenyl-nucleotide exchange factor activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0006915(apoptotic process);GO:0007166(cell surface receptor signaling pathway);GO:0031625(ubiquitin protein ligase binding);GO:0043066(negative regulation of apoptotic process);GO:0050790(regulation of catalytic activity);GO:0051085(chaperone cofactor-dependent protein refolding);GO:0051087(chaperone binding);GO:1900034(regulation of cellular response to heat)","04141(Protein processing in endoplasmic reticulum)","NA","NA","BCL2 associated athanogene 1 [Source:HGNC Symbol;Acc:HGNC:937]",{"v":0.018916,"d":"0.02"},{"v":0.016134,"d":"0.02"},{"v":0.080998,"d":"0.08"},{"v":16.833687,"d":"16.83"},{"v":11.428557,"d":"11.43"},{"v":0.000352,"d":"0.00"},{"v":0.00410606300992308,"d":"0.00"},{"v":-7.9280285180519,"d":"-7.93"},{"v":5.77865290858017e-5,"d":"0.00"},{"v":0.00675043280285265,"d":"0.01"},"down","yes"]
[87289,0,"chr17","+",48831035,48856174,"ENST00000513119",10,973,"ENSG00000136436","CALCOCO2","GO:0000421(autophagosome membrane);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005776(autophagosome);GO:0005829(cytosol);GO:0005856(cytoskeleton);GO:0006914(autophagy);GO:0016020(membrane);GO:0016032(viral process);GO:0031410(cytoplasmic vesicle);GO:0034341(response to interferon-gamma);GO:0042803(protein homodimerization activity);GO:0043231(intracellular membrane-bounded organelle);GO:0048471(perinuclear region of cytoplasm);GO:0098792(xenophagy);GO:1901098(positive regulation of autophagosome maturation)","04137(Mitophagy - animal)","K21348","NA","calcium binding and coiled-coil domain 2 [Source:HGNC Symbol;Acc:HGNC:29912]",{"v":1.505038,"d":"1.51"},{"v":7.256692,"d":"7.26"},0,0,0,0,"inf","inf",{"v":5.79971080826602e-5,"d":"0.00"},{"v":0.00675331710462515,"d":"0.01"},"up","yes"]
[198807,0,"chr9","+",121737151,121785530,"ENST00000648444",14,6805,"ENSG00000136848","DAB2IP","GO:0000122(negative regulation of transcription by RNA polymerase II);GO:0000165(MAPK cascade);GO:0000185(activation of MAPKKK activity);GO:0001525(angiogenesis);GO:0001933(negative regulation of protein phosphorylation);GO:0002376(immune system process);GO:0005096(GTPase activator activity);GO:0005123(death receptor binding);GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0006915(apoptotic process);GO:0006954(inflammatory response);GO:0006986(response to unfolded protein);GO:0007049(cell cycle);GO:0007165(signal transduction);GO:0007252(I-kappaB phosphorylation);GO:0007257(activation of JUN kinase activity);GO:0007275(multicellular organism development);GO:0008285(negative regulation of cell population proliferation);GO:0008625(extrinsic apoptotic signaling pathway via death domain receptors);GO:0010596(negative regulation of endothelial cell migration);GO:0010633(negative regulation of epithelial cell migration);GO:0010719(negative regulation of epithelial to mesenchymal transition);GO:0010976(positive regulation of neuron projection development);GO:0014067(negative regulation of phosphatidylinositol 3-kinase signaling);GO:0016020(membrane);GO:0016525(negative regulation of angiogenesis);GO:0017124(SH3 domain binding);GO:0019900(kinase binding);GO:0019901(protein kinase binding);GO:0021814(cell motility involved in cerebral cortex radial glia guided migration);GO:0021819(layer formation in cerebral cortex);GO:0030139(endocytic vesicle);GO:0030424(axon);GO:0030425(dendrite);GO:0030948(negative regulation of vascular endothelial growth factor receptor signaling pathway);GO:0031434(mitogen-activated protein kinase kinase binding);GO:0031435(mitogen-activated protein kinase kinase kinase binding);GO:0032088(negative regulation of NF-kappaB transcription factor activity);GO:0032266(phosphatidylinositol-3-phosphate binding);GO:0032809(neuronal cell body membrane);GO:0034144(negative regulation of toll-like receptor 4 signaling pathway);GO:0034260(negative regulation of GTPase activity);GO:0034620(cellular response to unfolded protein);GO:0035148(tube formation);GO:0035591(signaling adaptor activity);GO:0035924(cellular response to vascular endothelial growth factor stimulus);GO:0036312(phosphatidylinositol 3-kinase regulatory subunit binding);GO:0036324(vascular endothelial growth factor receptor-2 signaling pathway);GO:0038026(reelin-mediated signaling pathway);GO:0040008(regulation of growth);GO:0042059(negative regulation of epidermal growth factor receptor signaling pathway);GO:0042802(identical protein binding);GO:0042803(protein homodimerization activity);GO:0042995(cell projection);GO:0043025(neuronal cell body);GO:0043065(positive regulation of apoptotic process);GO:0043087(regulation of GTPase activity);GO:0043122(regulation of I-kappaB kinase/NF-kappaB signaling);GO:0043124(negative regulation of I-kappaB kinase/NF-kappaB signaling);GO:0043184(vascular endothelial growth factor receptor 2 binding);GO:0043254(regulation of protein complex assembly);GO:0043407(negative regulation of MAP kinase activity);GO:0043410(positive regulation of MAPK cascade);GO:0043497(regulation of protein heterodimerization activity);GO:0043507(positive regulation of JUN kinase activity);GO:0043547(positive regulation of GTPase activity);GO:0043548(phosphatidylinositol 3-kinase binding);GO:0043553(negative regulation of phosphatidylinositol 3-kinase activity);GO:0044257(cellular protein catabolic process);GO:0044300(cerebellar mossy fiber);GO:0044301(climbing fiber);GO:0044877(protein-containing complex binding);GO:0045087(innate immune response);GO:0045296(cadherin binding);GO:0045732(positive regulation of protein catabolic process);GO:0045892(negative regulation of transcription, DNA-templated);GO:0045944(positive regulation of transcription by RNA polymerase II);GO:0046330(positive regulation of JNK cascade);GO:0046580(negative regulation of Ras protein signal transduction);GO:0048147(negative regulation of fibroblast proliferation);GO:0048812(neuron projection morphogenesis);GO:0050680(negative regulation of epithelial cell proliferation);GO:0051721(protein phosphatase 2A binding);GO:0070059(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress);GO:0070273(phosphatidylinositol-4-phosphate binding);GO:0070317(negative regulation of G0 to G1 transition);GO:0070373(negative regulation of ERK1 and ERK2 cascade);GO:0071158(positive regulation of cell cycle arrest);GO:0071222(cellular response to lipopolysaccharide);GO:0071347(cellular response to interleukin-1);GO:0071356(cellular response to tumor necrosis factor);GO:0071364(cellular response to epidermal growth factor stimulus);GO:0071889(14-3-3 protein binding);GO:0071901(negative regulation of protein serine/threonine kinase activity);GO:0071902(positive regulation of protein serine/threonine kinase activity);GO:0072577(endothelial cell apoptotic process);GO:0090090(negative regulation of canonical Wnt signaling pathway);GO:0090129(positive regulation of synapse maturation);GO:1900006(positive regulation of dendrite development);GO:1900744(regulation of p38MAPK cascade);GO:1900747(negative regulation of vascular endothelial growth factor signaling pathway);GO:1901800(positive regulation of proteasomal protein catabolic process);GO:1903363(negative regulation of cellular protein catabolic process);GO:1903896(positive regulation of IRE1-mediated unfolded protein response);GO:1990032(parallel fiber);GO:1990597(AIP1-IRE1 complex);GO:2001224(positive regulation of neuron migration);GO:2001235(positive regulation of apoptotic signaling pathway)","04210(Apoptosis);04668(TNF signaling pathway)","K19901","NA","DAB2 interacting protein [Source:HGNC Symbol;Acc:HGNC:17294]",0,{"v":5.961698,"d":"5.96"},{"v":4.430216,"d":"4.43"},{"v":0.00906,"d":"0.01"},0,{"v":0.009563,"d":"0.01"},{"v":558.015035171562,"d":"558.02"},{"v":9.12416018436543,"d":"9.12"},{"v":5.87348268254426e-5,"d":"0.00"},{"v":0.00681736823823748,"d":"0.01"},"up","yes"]
[10459,0,"chr1","+",146949314,146996093,"ENST00000611443",28,5594,"ENSG00000268043","NBPF12","GO:0005737(cytoplasm)","NA","NA","NA","NBPF member 12 [Source:HGNC Symbol;Acc:HGNC:24297]",0,0,0,{"v":0.40088,"d":"0.40"},0,{"v":0.770634,"d":"0.77"},"-inf","-inf",{"v":5.951389801119e-5,"d":"0.00"},{"v":0.00688579590683609,"d":"0.01"},"down","yes"]
[54735,0,"chr14","-",23047660,23055826,"ENST00000267383",12,2873,"ENSG00000139880","CDH24","GO:0000902(cell morphogenesis);GO:0005509(calcium ion binding);GO:0005886(plasma membrane);GO:0005911(cell-cell junction);GO:0005913(cell-cell adherens junction);GO:0007043(cell-cell junction assembly);GO:0007155(cell adhesion);GO:0007156(homophilic cell adhesion via plasma membrane adhesion molecules);GO:0008092(cytoskeletal protein binding);GO:0009986(cell surface);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016339(calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules);GO:0016342(catenin complex);GO:0034332(adherens junction organization);GO:0042803(protein homodimerization activity);GO:0044331(cell-cell adhesion mediated by cadherin);GO:0045296(cadherin binding);GO:0046872(metal ion binding);GO:0098609(cell-cell adhesion)","NA","K06814","NA","cadherin 24 [Source:HGNC Symbol;Acc:HGNC:14265]",0,0,0,{"v":0.694114,"d":"0.69"},{"v":0.026461,"d":"0.03"},{"v":0.508508,"d":"0.51"},"-inf","-inf",{"v":6.1489591261725e-5,"d":"0.00"},{"v":0.00708824521466871,"d":"0.01"},"down","yes"]
[37139,0,"chr11","+",119084914,119093548,"ENST00000544387",13,1351,"ENSG00000256269","HMBS","GO:0004418(hydroxymethylbilane synthase activity);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0006779(porphyrin-containing compound biosynthetic process);GO:0006782(protoporphyrinogen IX biosynthetic process);GO:0006783(heme biosynthetic process);GO:0016740(transferase activity);GO:0018160(peptidyl-pyrromethane cofactor linkage);GO:0033014(tetrapyrrole biosynthetic process)","00860(Porphyrin and chlorophyll metabolism)","K01749","EC:2.5.1.61","hydroxymethylbilane synthase [Source:HGNC Symbol;Acc:HGNC:4982]",0,0,0,{"v":2.026133,"d":"2.03"},0,{"v":2.702965,"d":"2.70"},"-inf","-inf",{"v":6.16538807551696e-5,"d":"0.00"},{"v":0.00708824521466871,"d":"0.01"},"down","yes"]
[35050,0,"chr11","+",86800542,86811233,"ENST00000280258",2,3713,"ENSG00000150687","PRSS23","GO:0004252(serine-type endopeptidase activity);GO:0005576(extracellular region);GO:0005634(nucleus);GO:0005788(endoplasmic reticulum lumen);GO:0006508(proteolysis);GO:0008233(peptidase activity);GO:0008236(serine-type peptidase activity);GO:0016787(hydrolase activity);GO:0043687(post-translational protein modification);GO:0044267(cellular protein metabolic process);GO:0070062(extracellular exosome)","NA","K09627","EC:3.4.21.-","serine protease 23 [Source:HGNC Symbol;Acc:HGNC:14370]",{"v":1.251002,"d":"1.25"},{"v":1.302111,"d":"1.30"},{"v":1.218444,"d":"1.22"},{"v":36.429729,"d":"36.43"},{"v":32.534359,"d":"32.53"},{"v":1.099581,"d":"1.10"},{"v":0.0538304238677538,"d":"0.05"},{"v":-4.2154344044044,"d":"-4.22"},{"v":6.23490403211049e-5,"d":"0.00"},{"v":0.00714555405320424,"d":"0.01"},"down","yes"]
[13697,0,"chr1","+",167220890,167427345,"ENST00000271411",17,13945,"ENSG00000143190","POU2F1","GO:0000978(RNA polymerase II proximal promoter sequence-specific DNA binding);GO:0000979(RNA polymerase II core promoter sequence-specific DNA binding);GO:0000981(DNA-binding transcription factor activity, RNA polymerase II-specific);GO:0003677(DNA binding);GO:0003700(DNA-binding transcription factor activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005783(endoplasmic reticulum);GO:0006355(regulation of transcription, DNA-templated);GO:0019221(cytokine-mediated signaling pathway);GO:0042795(snRNA transcription by RNA polymerase II);GO:0043231(intracellular membrane-bounded organelle);GO:0043565(sequence-specific DNA binding);GO:0045892(negative regulation of transcription, DNA-templated);GO:0045944(positive regulation of transcription by RNA polymerase II);GO:0090575(RNA polymerase II transcription factor complex)","05168(Herpes simplex virus 1 infection)","NA","NA","POU class 2 homeobox 1 [Source:HGNC Symbol;Acc:HGNC:9212]",0,0,0,{"v":0.362857,"d":"0.36"},0,{"v":0.113893,"d":"0.11"},"-inf","-inf",{"v":6.43813706258967e-5,"d":"0.00"},{"v":0.0073552679082982,"d":"0.01"},"down","yes"]
[38132,0,"chr11","-",129899706,130002835,"ENST00000358825",22,6322,"ENSG00000170325","PRDM10","GO:0000979(RNA polymerase II core promoter sequence-specific DNA binding);GO:0000981(DNA-binding transcription factor activity, RNA polymerase II-specific);GO:0003676(nucleic acid binding);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0005634(nucleus);GO:0006357(regulation of transcription by RNA polymerase II);GO:0008168(methyltransferase activity);GO:0010468(regulation of gene expression);GO:0016740(transferase activity);GO:0032259(methylation);GO:0035097(histone methyltransferase complex);GO:0046872(metal ion binding)","NA","NA","NA","PR/SET domain 10 [Source:HGNC Symbol;Acc:HGNC:13995]",0,0,0,{"v":0.161209,"d":"0.16"},0,{"v":1.079435,"d":"1.08"},"-inf","-inf",{"v":6.47563989813887e-5,"d":"0.00"},{"v":0.00737492155170487,"d":"0.01"},"down","yes"]
[169129,0,"chr6","-",31687186,31703070,"ENST00000440843",18,1906,"ENSG00000204427","ABHD16A","GO:0005515(protein binding);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016787(hydrolase activity);GO:0047372(acylglycerol lipase activity);GO:0052651(monoacylglycerol catabolic process);GO:1905344(prostaglandin catabolic process)","NA","NA","NA","abhydrolase domain containing 16A [Source:HGNC Symbol;Acc:HGNC:13921]",0,0,0,0,{"v":2.180804,"d":"2.18"},{"v":1.298241,"d":"1.30"},"-inf","-inf",{"v":6.5103588306791e-5,"d":"0.00"},{"v":0.00738462999410532,"d":"0.01"},"down","yes"]
[127503,0,"chr20","-",46374438,46406599,"ENST00000488853",14,1250,"ENSG00000062598","ELMO2","GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0006909(phagocytosis);GO:0006915(apoptotic process);GO:0007010(cytoskeleton organization);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016477(cell migration);GO:0017124(SH3 domain binding);GO:0030971(receptor tyrosine kinase binding);GO:0038096(Fc-gamma receptor signaling pathway involved in phagocytosis);GO:0048010(vascular endothelial growth factor receptor signaling pathway);GO:0060326(cell chemotaxis);GO:0098609(cell-cell adhesion)","05100(Bacterial invasion of epithelial cells);05131(Shigellosis)","K18985","NA","engulfment and cell motility 2 [Source:HGNC Symbol;Acc:HGNC:17233]",{"v":1.973201,"d":"1.97"},{"v":3.368761,"d":"3.37"},0,0,0,0,"inf","inf",{"v":6.52481758356126e-5,"d":"0.00"},{"v":0.00738462999410532,"d":"0.01"},"up","yes"]
[42636,0,"chr12","+",49741809,49764934,"ENST00000423828",10,3254,"ENSG00000139644","TMBIM6","GO:0005515(protein binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005887(integral component of plasma membrane);GO:0006914(autophagy);GO:0006915(apoptotic process);GO:0006986(response to unfolded protein);GO:0010523(negative regulation of calcium ion transport into cytosol);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0019899(enzyme binding);GO:0031625(ubiquitin protein ligase binding);GO:0031966(mitochondrial membrane);GO:0032091(negative regulation of protein binding);GO:0032469(endoplasmic reticulum calcium ion homeostasis);GO:0033119(negative regulation of RNA splicing);GO:0034620(cellular response to unfolded protein);GO:0034976(response to endoplasmic reticulum stress);GO:0043066(negative regulation of apoptotic process);GO:0051025(negative regulation of immunoglobulin secretion);GO:0060698(endoribonuclease inhibitor activity);GO:0060702(negative regulation of endoribonuclease activity);GO:0070059(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress);GO:1902065(response to L-glutamate);GO:1902236(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway);GO:1903298(negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway);GO:1990441(negative regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress);GO:2001234(negative regulation of apoptotic signaling pathway)","NA","K21889","NA","transmembrane BAX inhibitor motif containing 6 [Source:HGNC Symbol;Acc:HGNC:11723]",0,0,{"v":0.17094,"d":"0.17"},{"v":5.783629,"d":"5.78"},{"v":7.72092,"d":"7.72"},{"v":7.125582,"d":"7.13"},{"v":0.0082859386593328,"d":"0.01"},{"v":-6.91511914455302,"d":"-6.92"},{"v":6.60228724188034e-5,"d":"0.00"},{"v":0.00744910234464326,"d":"0.01"},"down","yes"]
[105292,0,"chr19","-",45609638,45645629,"ENST00000587152",22,2763,"ENSG00000125746","EML2","GO:0005102(signaling receptor binding);GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0005819(spindle);GO:0005856(cytoskeleton);GO:0005874(microtubule);GO:0005875(microtubule associated complex);GO:0007601(visual perception);GO:0007605(sensory perception of sound);GO:0008017(microtubule binding);GO:0008022(protein C-terminus binding);GO:0010968(regulation of microtubule nucleation);GO:0015630(microtubule cytoskeleton);GO:0015631(tubulin binding);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0031115(negative regulation of microtubule polymerization);GO:0072686(mitotic spindle)","NA","K18595","NA","EMAP like 2 [Source:HGNC Symbol;Acc:HGNC:18035]",{"v":0.015197,"d":"0.02"},{"v":0.642099,"d":"0.64"},{"v":0.832752,"d":"0.83"},0,0,0,"inf","inf",{"v":6.82851781122673e-5,"d":"0.00"},{"v":0.00768049696847885,"d":"0.01"},"up","yes"]
[40697,0,"chr12","+",19236924,19361662,"ENST00000536974",22,3139,"ENSG00000052126","PLEKHA5","GO:0005515(protein binding);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0008150(biological_process);GO:0010314(phosphatidylinositol-5-phosphate binding);GO:0014069(postsynaptic density);GO:0016020(membrane);GO:0032266(phosphatidylinositol-3-phosphate binding);GO:0061458(reproductive system development);GO:0070273(phosphatidylinositol-4-phosphate binding);GO:0080025(phosphatidylinositol-3,5-bisphosphate binding);GO:0098978(glutamatergic synapse)","NA","NA","NA","pleckstrin homology domain containing A5 [Source:HGNC Symbol;Acc:HGNC:30036]",{"v":8.657993,"d":"8.66"},{"v":11.002092,"d":"11.00"},{"v":2.881326,"d":"2.88"},{"v":0.31892,"d":"0.32"},{"v":0.728452,"d":"0.73"},{"v":0.443218,"d":"0.44"},{"v":15.1224756639988,"d":"15.12"},{"v":3.91862243390447,"d":"3.92"},{"v":7.03531925974251e-5,"d":"0.00"},{"v":0.00788867742921128,"d":"0.01"},"up","yes"]
[192848,0,"chr8","+",132817408,132847580,"ENST00000460236",11,3393,"ENSG00000129292","PHF20L1","GO:0005515(protein binding);GO:0005634(nucleus);GO:0006355(regulation of transcription, DNA-templated);GO:0046872(metal ion binding)","NA","K18402","NA","PHD finger protein 20 like 1 [Source:HGNC Symbol;Acc:HGNC:24280]",{"v":0.050713,"d":"0.05"},{"v":0.007377,"d":"0.01"},0,{"v":2.999033,"d":"3.00"},{"v":5.988003,"d":"5.99"},{"v":0.083505,"d":"0.08"},{"v":0.0064042486550692,"d":"0.01"},{"v":-7.28675496080684,"d":"-7.29"},{"v":7.09893030462419e-5,"d":"0.00"},{"v":0.00793551193744606,"d":"0.01"},"down","yes"]
[205084,0,"chrX","+",102720743,102753540,"ENST00000457056",4,5155,"ENSG00000198908","BHLHB9","GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0007611(learning or memory);GO:0042803(protein homodimerization activity);GO:0043524(negative regulation of neuron apoptotic process);GO:0050769(positive regulation of neurogenesis);GO:0051965(positive regulation of synapse assembly);GO:0061003(positive regulation of dendritic spine morphogenesis);GO:0070062(extracellular exosome)","NA","NA","NA","basic helix-loop-helix family member b9 [Source:HGNC Symbol;Acc:HGNC:29353]",{"v":0.007906,"d":"0.01"},{"v":0.293368,"d":"0.29"},{"v":1.137578,"d":"1.14"},0,{"v":0.003536,"d":"0.00"},0,{"v":406.915158371041,"d":"406.92"},{"v":8.66858421434804,"d":"8.67"},{"v":7.22839677390589e-5,"d":"0.00"},{"v":0.00800132815303082,"d":"0.01"},"up","yes"]
[174363,0,"chr6","-",137197497,137219160,"ENST00000646898",8,2519,"ENSG00000027697","IFNGR1","GO:0004896(cytokine receptor activity);GO:0004906(interferon-gamma receptor activity);GO:0005515(protein binding);GO:0005886(plasma membrane);GO:0005887(integral component of plasma membrane);GO:0007165(signal transduction);GO:0009615(response to virus);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0019221(cytokine-mediated signaling pathway);GO:0019955(cytokine binding);GO:0060333(interferon-gamma-mediated signaling pathway);GO:0060334(regulation of interferon-gamma-mediated signaling pathway)","04060(Cytokine-cytokine receptor interaction);04066(HIF-1 signaling pathway);04217(Necroptosis);04380(Osteoclast differentiation);04630(Jak-STAT signaling pathway);04650(Natural killer cell mediated cytotoxicity);04658(Th1 and Th2 cell differentiation);04659(Th17 cell differentiation);05132(Salmonella infection);05140(Leishmaniasis);05142(Chagas disease (American trypanosomiasis));05145(Toxoplasmosis);05152(Tuberculosis);05164(Influenza A);05167(Kaposi sarcoma-associated herpesvirus infection);05168(Herpes simplex virus 1 infection);05200(Pathways in cancer);05321(Inflammatory bowel disease (IBD))","K05132","NA","interferon gamma receptor 1 [Source:HGNC Symbol;Acc:HGNC:5439]",{"v":7.168398,"d":"7.17"},{"v":6.004472,"d":"6.00"},{"v":0.151803,"d":"0.15"},{"v":0.041717,"d":"0.04"},{"v":0.123607,"d":"0.12"},{"v":0.011188,"d":"0.01"},{"v":75.4887656363307,"d":"75.49"},{"v":6.23819005102407,"d":"6.24"},{"v":7.2315171721772e-5,"d":"0.00"},{"v":0.00800132815303082,"d":"0.01"},"up","yes"]
[188109,0,"chr8","-",30785616,30812597,"ENST00000518564",3,691,"ENSG00000104695","PPP2CB","GO:0000159(protein phosphatase type 2A complex);GO:0000775(chromosome, centromeric region);GO:0000922(spindle pole);GO:0004721(phosphoprotein phosphatase activity);GO:0004722(protein serine/threonine phosphatase activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005694(chromosome);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005856(cytoskeleton);GO:0006470(protein dephosphorylation);GO:0008022(protein C-terminus binding);GO:0008637(apoptotic mitochondrial changes);GO:0010288(response to lead ion);GO:0010468(regulation of gene expression);GO:0016787(hydrolase activity);GO:0034976(response to endoplasmic reticulum stress);GO:0035970(peptidyl-threonine dephosphorylation);GO:0042542(response to hydrogen peroxide);GO:0043161(proteasome-mediated ubiquitin-dependent protein catabolic process);GO:0046580(negative regulation of Ras protein signal transduction);GO:0046677(response to antibiotic);GO:0046872(metal ion binding);GO:0048156(tau protein binding);GO:0070262(peptidyl-serine dephosphorylation);GO:1904528(positive regulation of microtubule binding)","03015(mRNA surveillance pathway);04071(Sphingolipid signaling pathway);04114(Oocyte meiosis);04136(Autophagy - other);04140(Autophagy - animal);04151(PI3K-Akt signaling pathway);04152(AMPK signaling pathway);04261(Adrenergic signaling in cardiomyocytes);04350(TGF-beta signaling pathway);04390(Hippo signaling pathway);04530(Tight junction);04728(Dopaminergic synapse);04730(Long-term depression);05142(Chagas disease (American trypanosomiasis));05160(Hepatitis C);05165(Human papillomavirus infection)","NA","NA","protein phosphatase 2 catalytic subunit beta [Source:HGNC Symbol;Acc:HGNC:9300]",0,{"v":0.000979,"d":"0.00"},0,{"v":7.960514,"d":"7.96"},0,{"v":7.480597,"d":"7.48"},{"v":6.34021735871208e-5,"d":"0.00"},{"v":-13.9451081739837,"d":"-13.95"},{"v":7.24049224808847e-5,"d":"0.00"},{"v":0.00800132815303082,"d":"0.01"},"down","yes"]
[11048,0,"chr1","-",150996835,151008365,"ENST00000361936",11,2817,"ENSG00000143409","MINDY1","GO:0004843(thiol-dependent ubiquitin-specific protease activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0006508(proteolysis);GO:0008150(biological_process);GO:0008233(peptidase activity);GO:0008234(cysteine-type peptidase activity);GO:0016604(nuclear body);GO:0016787(hydrolase activity);GO:0016807(cysteine-type carboxypeptidase activity);GO:0036435(K48-linked polyubiquitin modification-dependent protein binding);GO:0036459(thiol-dependent ubiquitinyl hydrolase activity);GO:0071108(protein K48-linked deubiquitination);GO:1990380(Lys48-specific deubiquitinase activity)","NA","K01309","EC:3.4.19.12","MINDY lysine 48 deubiquitinase 1 [Source:HGNC Symbol;Acc:HGNC:25648]",{"v":0.667476,"d":"0.67"},0,{"v":1.700326,"d":"1.70"},0,0,0,"inf","inf",{"v":7.24590410775431e-5,"d":"0.00"},{"v":0.00800132815303082,"d":"0.01"},"up","yes"]
[147248,0,"chr3","+",184135385,184145311,"ENST00000481054",15,3460,"ENSG00000145191","EIF2B5","GO:0001541(ovarian follicle development);GO:0003743(translation initiation factor activity);GO:0005085(guanyl-nucleotide exchange factor activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005851(eukaryotic translation initiation factor 2B complex);GO:0006412(translation);GO:0006413(translational initiation);GO:0007568(aging);GO:0009408(response to heat);GO:0009749(response to glucose);GO:0010226(response to lithium ion);GO:0014002(astrocyte development);GO:0014003(oligodendrocyte development);GO:0021766(hippocampus development);GO:0031369(translation initiation factor binding);GO:0034976(response to endoplasmic reticulum stress);GO:0042552(myelination);GO:0043065(positive regulation of apoptotic process);GO:0043434(response to peptide hormone);GO:0045727(positive regulation of translation);GO:0045948(positive regulation of translational initiation);GO:0048708(astrocyte differentiation);GO:0050852(T cell receptor signaling pathway)","03013(RNA transport);05168(Herpes simplex virus 1 infection)","K03240","NA","eukaryotic translation initiation factor 2B subunit epsilon [Source:HGNC Symbol;Acc:HGNC:3261]",{"v":0.688118,"d":"0.69"},{"v":0.6238,"d":"0.62"},{"v":0.004191,"d":"0.00"},0,0,0,"inf","inf",{"v":7.32424212857146e-5,"d":"0.00"},{"v":0.0080490504108734,"d":"0.01"},"up","yes"]
[52459,0,"chr13","+",75760434,75858672,"ENST00000321797",29,5647,"ENSG00000136153","LMO7","GO:0000151(ubiquitin ligase complex);GO:0000209(protein polyubiquitination);GO:0004842(ubiquitin-protein transferase activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005635(nuclear envelope);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0005913(cell-cell adherens junction);GO:0005925(focal adhesion);GO:0008022(protein C-terminus binding);GO:0009986(cell surface);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016324(apical plasma membrane);GO:0016567(protein ubiquitination);GO:0023051(regulation of signaling);GO:0030155(regulation of cell adhesion);GO:0042805(actinin binding);GO:0043687(post-translational protein modification);GO:0045944(positive regulation of transcription by RNA polymerase II);GO:0046872(metal ion binding);GO:0098609(cell-cell adhesion)","04520(Adherens junction)","K06084","NA","LIM domain 7 [Source:HGNC Symbol;Acc:HGNC:6646]",0,0,0,{"v":0.54261,"d":"0.54"},0,{"v":0.546734,"d":"0.55"},"-inf","-inf",{"v":7.33343156069115e-5,"d":"0.00"},{"v":0.0080490504108734,"d":"0.01"},"down","yes"]
[150294,0,"chr4","-",22387708,22455834,"ENST00000282943",17,3534,"ENSG00000152990","ADGRA3","GO:0004888(transmembrane signaling receptor activity);GO:0004930(G protein-coupled receptor activity);GO:0005515(protein binding);GO:0007165(signal transduction);GO:0007166(cell surface receptor signaling pathway);GO:0007186(G protein-coupled receptor signaling pathway);GO:0009897(external side of plasma membrane);GO:0016020(membrane);GO:0016021(integral component of membrane)","NA","K08462","NA","adhesion G protein-coupled receptor A3 [Source:HGNC Symbol;Acc:HGNC:13839]",0,{"v":1.223955,"d":"1.22"},{"v":0.618893,"d":"0.62"},0,0,0,"inf","inf",{"v":7.63117536180049e-5,"d":"0.00"},{"v":0.0083506205088618,"d":"0.01"},"up","yes"]
[174450,0,"chr6","-",138904870,138987881,"ENST00000409812",17,2511,"ENSG00000135597","REPS1","GO:0005509(calcium ion binding);GO:0005515(protein binding);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0005905(clathrin-coated pit);GO:0006898(receptor-mediated endocytosis);GO:0016020(membrane);GO:0017124(SH3 domain binding);GO:0046872(metal ion binding);GO:0061024(membrane organization)","NA","K20068","NA","RALBP1 associated Eps domain containing 1 [Source:HGNC Symbol;Acc:HGNC:15578]",0,0,0,0,{"v":1.728226,"d":"1.73"},{"v":0.830615,"d":"0.83"},"-inf","-inf",{"v":7.72363271097361e-5,"d":"0.00"},{"v":0.00842641370539553,"d":"0.01"},"down","yes"]
[205506,0,"chrX","+",111681170,111760645,"ENST00000610588",27,4175,"ENSG00000101901","ALG13","GO:0003723(RNA binding);GO:0003824(catalytic activity);GO:0004577(N-acetylglucosaminyldiphosphodolichol N-acetylglucosaminyltransferase activity);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0006488(dolichol-linked oligosaccharide biosynthetic process);GO:0006508(proteolysis);GO:0008152(metabolic process);GO:0008233(peptidase activity);GO:0008234(cysteine-type peptidase activity);GO:0016740(transferase activity);GO:0016757(transferase activity, transferring glycosyl groups);GO:0016758(transferase activity, transferring hexosyl groups);GO:0016787(hydrolase activity);GO:0036459(thiol-dependent ubiquitinyl hydrolase activity)","00510(N-Glycan biosynthesis)","K07432","EC:2.4.1.141","ALG13, UDP-N-acetylglucosaminyltransferase subunit [Source:HGNC Symbol;Acc:HGNC:30881]",{"v":1.006989,"d":"1.01"},0,{"v":0.527004,"d":"0.53"},0,0,0,"inf","inf",{"v":7.84523946891509e-5,"d":"0.00"},{"v":0.00853345957801453,"d":"0.01"},"up","yes"]
[198686,0,"chr9","-",120389201,120448072,"ENST00000425647",16,2747,"ENSG00000136861","CDK5RAP2","GO:0000086(G2/M transition of mitotic cell cycle);GO:0000132(establishment of mitotic spindle orientation);GO:0000226(microtubule cytoskeleton organization);GO:0000242(pericentriolar material);GO:0000922(spindle pole);GO:0001578(microtubule bundle formation);GO:0005515(protein binding);GO:0005516(calmodulin binding);GO:0005737(cytoplasm);GO:0005794(Golgi apparatus);GO:0005813(centrosome);GO:0005815(microtubule organizing center);GO:0005829(cytosol);GO:0005856(cytoskeleton);GO:0005874(microtubule);GO:0007059(chromosome segregation);GO:0007098(centrosome cycle);GO:0007099(centriole replication);GO:0007420(brain development);GO:0008017(microtubule binding);GO:0008274(gamma-tubulin ring complex);GO:0010389(regulation of G2/M transition of mitotic cell cycle);GO:0015631(tubulin binding);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0019901(protein kinase binding);GO:0022008(neurogenesis);GO:0030054(cell junction);GO:0031023(microtubule organizing center organization);GO:0031116(positive regulation of microtubule polymerization);GO:0035371(microtubule plus-end);GO:0043015(gamma-tubulin binding);GO:0044212(transcription regulatory region DNA binding);GO:0045664(regulation of neuron differentiation);GO:0045665(negative regulation of neuron differentiation);GO:0045893(positive regulation of transcription, DNA-templated);GO:0046600(negative regulation of centriole replication);GO:0048471(perinuclear region of cytoplasm);GO:0070062(extracellular exosome);GO:0090266(regulation of mitotic cell cycle spindle assembly checkpoint);GO:0097431(mitotic spindle pole);GO:0097711(ciliary basal body-plasma membrane docking)","NA","K16542","NA","CDK5 regulatory subunit associated protein 2 [Source:HGNC Symbol;Acc:HGNC:18672]",0,{"v":1.188281,"d":"1.19"},{"v":1.125414,"d":"1.13"},0,0,0,"inf","inf",{"v":8.03434617849954e-5,"d":"0.00"},{"v":0.00871306855716084,"d":"0.01"},"up","yes"]
[34371,0,"chr11","+",75562217,75572542,"ENST00000649490",6,3523,"ENSG00000149257","SERPINH1","GO:0003433(chondrocyte development involved in endochondral bone morphogenesis);GO:0003723(RNA binding);GO:0004867(serine-type endopeptidase inhibitor activity);GO:0005518(collagen binding);GO:0005581(collagen trimer);GO:0005615(extracellular space);GO:0005737(cytoplasm);GO:0005783(endoplasmic reticulum);GO:0005788(endoplasmic reticulum lumen);GO:0005793(endoplasmic reticulum-Golgi intermediate compartment);GO:0006986(response to unfolded protein);GO:0010951(negative regulation of endopeptidase activity);GO:0030199(collagen fibril organization);GO:0032964(collagen biosynthetic process);GO:0045121(membrane raft);GO:0051082(unfolded protein binding);GO:0051604(protein maturation);GO:0062023(collagen-containing extracellular matrix)","NA","NA","NA","serpin family H member 1 [Source:HGNC Symbol;Acc:HGNC:1546]",{"v":2.743328,"d":"2.74"},{"v":0.009866,"d":"0.01"},{"v":8.357374,"d":"8.36"},{"v":0.011313,"d":"0.01"},{"v":0.022856,"d":"0.02"},{"v":0.046492,"d":"0.05"},{"v":137.743990280309,"d":"137.74"},{"v":7.10584556568962,"d":"7.11"},{"v":8.11534397877596e-5,"d":"0.00"},{"v":0.00877471567705151,"d":"0.01"},"up","yes"]
[168685,0,"chr6","-",30653119,30661983,"ENST00000376437",12,1933,"ENSG00000204560","DHX16","GO:0000166(nucleotide binding);GO:0000398(mRNA splicing, via spliceosome);GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0003724(RNA helicase activity);GO:0004386(helicase activity);GO:0005515(protein binding);GO:0005524(ATP binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005681(spliceosomal complex);GO:0006397(mRNA processing);GO:0008380(RNA splicing);GO:0016787(hydrolase activity);GO:0016887(ATPase activity);GO:0034459(ATP-dependent 3'-5' RNA helicase activity)","03040(Spliceosome)","K12813","EC:3.6.4.13","DEAH-box helicase 16 [Source:HGNC Symbol;Acc:HGNC:2739]",{"v":1.236369,"d":"1.24"},{"v":6.128641,"d":"6.13"},{"v":7.138234,"d":"7.14"},{"v":0.219637,"d":"0.22"},{"v":0.175613,"d":"0.18"},{"v":0.184556,"d":"0.18"},{"v":25.0139598417402,"d":"25.01"},{"v":4.64466155671775,"d":"4.64"},{"v":8.48423255138111e-5,"d":"0.00"},{"v":0.0091463551510883,"d":"0.01"},"up","yes"]
[99631,0,"chr19","+",12945855,12953269,"ENST00000591499",8,1350,"ENSG00000179262","RAD23A","GO:0000502(proteasome complex);GO:0003684(damaged DNA binding);GO:0003697(single-stranded DNA binding);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0005815(microtubule organizing center);GO:0005829(cytosol);GO:0006281(DNA repair);GO:0006289(nucleotide-excision repair);GO:0006974(cellular response to DNA damage stimulus);GO:0016032(viral process);GO:0016579(protein deubiquitination);GO:0019900(kinase binding);GO:0031593(polyubiquitin modification-dependent protein binding);GO:0031648(protein destabilization);GO:0032434(regulation of proteasomal ubiquitin-dependent protein catabolic process);GO:0032436(positive regulation of proteasomal ubiquitin-dependent protein catabolic process);GO:0032991(protein-containing complex);GO:0043130(ubiquitin binding);GO:0043161(proteasome-mediated ubiquitin-dependent protein catabolic process);GO:0043231(intracellular membrane-bounded organelle);GO:0045070(positive regulation of viral genome replication);GO:0045787(positive regulation of cell cycle);GO:0070628(proteasome binding);GO:1990381(ubiquitin-specific protease binding)","03420(Nucleotide excision repair);04141(Protein processing in endoplasmic reticulum)","K10839","NA","RAD23 homolog A, nucleotide excision repair protein [Source:HGNC Symbol;Acc:HGNC:9812]",{"v":0.000326,"d":"0.00"},{"v":0.000324,"d":"0.00"},{"v":0.000486,"d":"0.00"},{"v":0.000563,"d":"0.00"},{"v":2.054945,"d":"2.05"},{"v":2.967391,"d":"2.97"},{"v":0.000226164213136677,"d":"0.00"},{"v":-12.1103417155391,"d":"-12.11"},{"v":8.86721929447538e-5,"d":"0.00"},{"v":0.00953094902273049,"d":"0.01"},"down","yes"]
[195819,0,"chr9","-",37588642,37592596,"ENST00000544379",2,635,"ENSG00000175768","TOMM5","GO:0005739(mitochondrion);GO:0005741(mitochondrial outer membrane);GO:0005742(mitochondrial outer membrane translocase complex);GO:0006626(protein targeting to mitochondrion);GO:0008565(protein transporter activity);GO:0015031(protein transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016236(macroautophagy)","NA","K17773","NA","translocase of outer mitochondrial membrane 5 [Source:HGNC Symbol;Acc:HGNC:31369]",{"v":8.843567,"d":"8.84"},0,{"v":7.553372,"d":"7.55"},0,{"v":0.017263,"d":"0.02"},0,{"v":949.831373457684,"d":"949.83"},{"v":9.89152759977629,"d":"9.89"},{"v":8.95924917733923e-5,"d":"0.00"},{"v":0.00960146084403345,"d":"0.01"},"up","yes"]
[53034,0,"chr13","+",99498956,99563334,"ENST00000642475",19,3858,"ENSG00000125304","TM9SF2","GO:0005768(endosome);GO:0005887(integral component of plasma membrane);GO:0010008(endosome membrane);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0070062(extracellular exosome);GO:0072657(protein localization to membrane)","NA","K17086","NA","transmembrane 9 superfamily member 2 [Source:HGNC Symbol;Acc:HGNC:11865]",{"v":0.060933,"d":"0.06"},{"v":0.046589,"d":"0.05"},{"v":0.48328,"d":"0.48"},{"v":21.22847,"d":"21.23"},{"v":23.761633,"d":"23.76"},{"v":0.050777,"d":"0.05"},{"v":0.0131170172518832,"d":"0.01"},{"v":-6.25241649460094,"d":"-6.25"},{"v":9.04407303594925e-5,"d":"0.00"},{"v":0.00966181258216686,"d":"0.01"},"down","yes"]
[44656,0,"chr12","-",57254733,57295479,"ENST00000429355",15,2266,"ENSG00000179912","R3HDM2","GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0005634(nucleus)","NA","NA","NA","R3H domain containing 2 [Source:HGNC Symbol;Acc:HGNC:29167]",{"v":0.542635,"d":"0.54"},{"v":0.096933,"d":"0.10"},{"v":0.372417,"d":"0.37"},0,0,0,"inf","inf",{"v":9.06875334577181e-5,"d":"0.00"},{"v":0.00966181258216686,"d":"0.01"},"up","yes"]
[101417,0,"chr19","-",19785842,19821709,"ENST00000443905",6,4095,"ENSG00000081665","ZNF506","GO:0000981(DNA-binding transcription factor activity, RNA polymerase II-specific);GO:0003676(nucleic acid binding);GO:0003677(DNA binding);GO:0005622(intracellular);GO:0005634(nucleus);GO:0005730(nucleolus);GO:0006355(regulation of transcription, DNA-templated);GO:0006357(regulation of transcription by RNA polymerase II);GO:0046872(metal ion binding)","05168(Herpes simplex virus 1 infection)","K09228","NA","zinc finger protein 506 [Source:HGNC Symbol;Acc:HGNC:23780]",0,0,0,{"v":0.763118,"d":"0.76"},0,{"v":0.694124,"d":"0.69"},"-inf","-inf",{"v":9.19759597588163e-5,"d":"0.00"},{"v":0.00976680364294519,"d":"0.01"},"down","yes"]
[13770,0,"chr1","-",168079543,168137667,"ENST00000537209",7,8256,"ENSG00000143147","GPR161","GO:0004930(G protein-coupled receptor activity);GO:0005886(plasma membrane);GO:0005929(cilium);GO:0007165(signal transduction);GO:0007186(G protein-coupled receptor signaling pathway);GO:0007189(adenylate cyclase-activating G protein-coupled receptor signaling pathway);GO:0007275(multicellular organism development);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0030666(endocytic vesicle membrane);GO:0042995(cell projection);GO:0055037(recycling endosome);GO:0060170(ciliary membrane);GO:1901621(negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning)","04340(Hedgehog signaling pathway)","K08439","NA","G protein-coupled receptor 161 [Source:HGNC Symbol;Acc:HGNC:23694]",0,{"v":0.067383,"d":"0.07"},{"v":0.022004,"d":"0.02"},{"v":0.133093,"d":"0.13"},{"v":3.09845,"d":"3.10"},{"v":4.382418,"d":"4.38"},{"v":0.0117398815150222,"d":"0.01"},{"v":-6.41243834168046,"d":"-6.41"},{"v":9.22106702320451e-5,"d":"0.00"},{"v":0.00976680364294519,"d":"0.01"},"down","yes"]
[156727,0,"chr4","-",184755595,184826119,"ENST00000454703",20,3636,"ENSG00000151726","ACSL1","GO:0000166(nucleotide binding);GO:0001676(long-chain fatty acid metabolic process);GO:0003824(catalytic activity);GO:0004467(long-chain fatty acid-CoA ligase activity);GO:0005524(ATP binding);GO:0005739(mitochondrion);GO:0005741(mitochondrial outer membrane);GO:0005777(peroxisome);GO:0005778(peroxisomal membrane);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005886(plasma membrane);GO:0006629(lipid metabolic process);GO:0006631(fatty acid metabolic process);GO:0007584(response to nutrient);GO:0008610(lipid biosynthetic process);GO:0010033(response to organic substance);GO:0014070(response to organic cyclic compound);GO:0015908(fatty acid transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016874(ligase activity);GO:0019216(regulation of lipid metabolic process);GO:0019432(triglyceride biosynthetic process);GO:0031090(organelle membrane);GO:0033211(adiponectin-activated signaling pathway);GO:0034201(response to oleic acid);GO:0035338(long-chain fatty-acyl-CoA biosynthetic process);GO:0036109(alpha-linolenic acid metabolic process);GO:0042178(xenobiotic catabolic process);GO:0042493(response to drug);GO:0043231(intracellular membrane-bounded organelle);GO:0043651(linoleic acid metabolic process);GO:0044539(long-chain fatty acid import into cell);GO:0071902(positive regulation of protein serine/threonine kinase activity);GO:0102391(decanoate-CoA ligase activity);GO:0120162(positive regulation of cold-induced thermogenesis)","00061(Fatty acid biosynthesis);00071(Fatty acid degradation);03320(PPAR signaling pathway);04146(Peroxisome);04216(Ferroptosis);04714(Thermogenesis);04920(Adipocytokine signaling pathway)","K01897","EC:6.2.1.3","acyl-CoA synthetase long chain family member 1 [Source:HGNC Symbol;Acc:HGNC:3569]",{"v":0.370036,"d":"0.37"},{"v":4.55076,"d":"4.55"},{"v":32.102871,"d":"32.10"},{"v":0.308109,"d":"0.31"},{"v":0.341977,"d":"0.34"},{"v":0.494946,"d":"0.49"},{"v":32.3341766867651,"d":"32.33"},{"v":5.01498797092823,"d":"5.01"},{"v":9.2958721301602e-5,"d":"0.00"},{"v":0.00981741379327675,"d":"0.01"},"up","yes"]
[76372,0,"chr16","-",67438014,67441732,"ENST00000568620",4,3390,"ENSG00000159720","ATP6V0D1","GO:0005515(protein binding);GO:0005765(lysosomal membrane);GO:0005769(early endosome);GO:0005813(centrosome);GO:0006811(ion transport);GO:0006879(cellular iron ion homeostasis);GO:0007034(vacuolar transport);GO:0007035(vacuolar acidification);GO:0007420(brain development);GO:0008021(synaptic vesicle);GO:0008286(insulin receptor signaling pathway);GO:0008553(proton-exporting ATPase activity, phosphorylative mechanism);GO:0010008(endosome membrane);GO:0015078(proton transmembrane transporter activity);GO:0015991(ATP hydrolysis coupled proton transport);GO:0016020(membrane);GO:0016241(regulation of macroautophagy);GO:0016324(apical plasma membrane);GO:0016471(vacuolar proton-transporting V-type ATPase complex);GO:0030030(cell projection organization);GO:0030670(phagocytic vesicle membrane);GO:0032991(protein-containing complex);GO:0033179(proton-transporting V-type ATPase, V0 domain);GO:0033181(plasma membrane proton-transporting V-type ATPase complex);GO:0033572(transferrin transport);GO:0034220(ion transmembrane transport);GO:0036295(cellular response to increased oxygen levels);GO:0036498(IRE1-mediated unfolded protein response);GO:0043005(neuron projection);GO:0043679(axon terminus);GO:0044877(protein-containing complex binding);GO:0046961(proton-transporting ATPase activity, rotational mechanism);GO:0060271(cilium assembly);GO:0070062(extracellular exosome);GO:0090383(phagosome acidification);GO:1902600(proton transmembrane transport)","00190(Oxidative phosphorylation);04142(Lysosome);04145(Phagosome);04721(Synaptic vesicle cycle);04966(Collecting duct acid secretion);05110(Vibrio cholerae infection);05120(Epithelial cell signaling in Helicobacter pylori infection);05152(Tuberculosis);05165(Human papillomavirus infection);05203(Viral carcinogenesis);05323(Rheumatoid arthritis)","NA","NA","ATPase H+ transporting V0 subunit d1 [Source:HGNC Symbol;Acc:HGNC:13724]",{"v":4.990317,"d":"4.99"},{"v":3.844364,"d":"3.84"},{"v":2.79336,"d":"2.79"},{"v":0.164423,"d":"0.16"},{"v":0.310557,"d":"0.31"},{"v":0.204087,"d":"0.20"},{"v":17.1235548185967,"d":"17.12"},{"v":4.09791032856499,"d":"4.10"},{"v":9.62496952818964e-5,"d":"0.00"},{"v":0.0101355113901197,"d":"0.01"},"up","yes"]
[14634,0,"chr1","+",183472502,183554186,"ENST00000347615",22,5788,"ENSG00000116698","SMG7","GO:0000184(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005697(telomerase holoenzyme complex);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0006406(mRNA export from nucleus);GO:0007004(telomere maintenance via telomerase);GO:0032210(regulation of telomere maintenance via telomerase);GO:0035303(regulation of dephosphorylation);GO:0042162(telomeric DNA binding);GO:0045111(intermediate filament cytoskeleton);GO:0051721(protein phosphatase 2A binding);GO:0070034(telomerase RNA binding)","03015(mRNA surveillance pathway)","K14409","NA","SMG7, nonsense mediated mRNA decay factor [Source:HGNC Symbol;Acc:HGNC:16792]",{"v":0.81402,"d":"0.81"},{"v":0.698851,"d":"0.70"},{"v":0.483433,"d":"0.48"},{"v":7.178122,"d":"7.18"},{"v":7.136343,"d":"7.14"},{"v":3.758096,"d":"3.76"},{"v":0.110460493119929,"d":"0.11"},{"v":-3.17839762184349,"d":"-3.18"},{"v":9.67187443674321e-5,"d":"0.00"},{"v":0.0101554681585804,"d":"0.01"},"down","yes"]
[108549,0,"chr19","+",56368099,56379528,"ENST00000467807",7,3209,"ENSG00000240225","ZNF542P","NA","NA","NA","NA","zinc finger protein 542, pseudogene [Source:HGNC Symbol;Acc:HGNC:25393]",{"v":0.003918,"d":"0.00"},{"v":1.55859,"d":"1.56"},{"v":1.632028,"d":"1.63"},{"v":0.007013,"d":"0.01"},0,0,{"v":455.516326821617,"d":"455.52"},{"v":8.83135895445506,"d":"8.83"},{"v":0.000100876990259573,"d":"0.00"},{"v":0.0105615592395686,"d":"0.01"},"up","yes"]
[29079,0,"chr11","+",35139306,35223320,"ENST00000442151",9,1825,"ENSG00000026508","CD44","GO:0004888(transmembrane signaling receptor activity);GO:0004896(cytokine receptor activity);GO:0005515(protein binding);GO:0005518(collagen binding);GO:0005540(hyaluronic acid binding);GO:0005794(Golgi apparatus);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0005887(integral component of plasma membrane);GO:0005902(microvillus);GO:0005925(focal adhesion);GO:0006954(inflammatory response);GO:0007155(cell adhesion);GO:0007160(cell-matrix adhesion);GO:0009986(cell surface);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016323(basolateral plasma membrane);GO:0016324(apical plasma membrane);GO:0016477(cell migration);GO:0022617(extracellular matrix disassembly);GO:0030198(extracellular matrix organization);GO:0030214(hyaluronan catabolic process);GO:0030667(secretory granule membrane);GO:0031258(lamellipodium membrane);GO:0033138(positive regulation of peptidyl-serine phosphorylation);GO:0033674(positive regulation of kinase activity);GO:0034116(positive regulation of heterotypic cell-cell adhesion);GO:0035692(macrophage migration inhibitory factor receptor complex);GO:0042110(T cell activation);GO:0042995(cell projection);GO:0043066(negative regulation of apoptotic process);GO:0043154(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process);GO:0043312(neutrophil degranulation);GO:0043518(negative regulation of DNA damage response, signal transduction by p53 class mediator);GO:0044319(wound healing, spreading of cells);GO:0044344(cellular response to fibroblast growth factor stimulus);GO:0050731(positive regulation of peptidyl-tyrosine phosphorylation);GO:0050900(leukocyte migration);GO:0051216(cartilage development);GO:0060333(interferon-gamma-mediated signaling pathway);GO:0070062(extracellular exosome);GO:0070374(positive regulation of ERK1 and ERK2 cascade);GO:0070487(monocyte aggregation);GO:0098609(cell-cell adhesion);GO:1900625(positive regulation of monocyte aggregation);GO:1902166(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator);GO:2000392(regulation of lamellipodium morphogenesis)","04512(ECM-receptor interaction);04640(Hematopoietic cell lineage);05131(Shigellosis);05169(Epstein-Barr virus infection);05205(Proteoglycans in cancer);05206(MicroRNAs in cancer)","NA","NA","CD44 molecule (Indian blood group) [Source:HGNC Symbol;Acc:HGNC:1681]",{"v":0.041389,"d":"0.04"},{"v":0.082303,"d":"0.08"},{"v":0.048184,"d":"0.05"},{"v":6.487496,"d":"6.49"},{"v":0.474262,"d":"0.47"},{"v":1.020814,"d":"1.02"},{"v":0.0215314061683377,"d":"0.02"},{"v":-5.53741364798244,"d":"-5.54"},{"v":0.000103934920142806,"d":"0.00"},{"v":0.0108504472666326,"d":"0.01"},"down","yes"]
[55180,0,"chr14","-",24189149,24195441,"ENST00000261789",6,2200,"ENSG00000100926","TM9SF1","GO:0000421(autophagosome membrane);GO:0005764(lysosome);GO:0005765(lysosomal membrane);GO:0006914(autophagy);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0031410(cytoplasmic vesicle);GO:0072657(protein localization to membrane)","NA","K17085","NA","transmembrane 9 superfamily member 1 [Source:HGNC Symbol;Acc:HGNC:11864]",{"v":0.919554,"d":"0.92"},{"v":25.019989,"d":"25.02"},{"v":1.011832,"d":"1.01"},{"v":0.108467,"d":"0.11"},{"v":0.254724,"d":"0.25"},{"v":0.01252,"d":"0.01"},{"v":71.7343250530328,"d":"71.73"},{"v":6.16459171219721,"d":"6.16"},{"v":0.000104420558618946,"d":"0.00"},{"v":0.0108617440534077,"d":"0.01"},"up","yes"]
[35382,0,"chr11","+",93784498,93812277,"ENST00000640521",11,2047,"ENSG00000042429","MED17","GO:0000151(ubiquitin ligase complex);GO:0003712(transcription coregulator activity);GO:0003713(transcription coactivator activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005667(transcription factor complex);GO:0006357(regulation of transcription by RNA polymerase II);GO:0006367(transcription initiation from RNA polymerase II promoter);GO:0016020(membrane);GO:0016567(protein ubiquitination);GO:0016592(mediator complex);GO:0019827(stem cell population maintenance);GO:0030374(nuclear receptor transcription coactivator activity);GO:0042809(vitamin D receptor binding);GO:0045893(positive regulation of transcription, DNA-templated);GO:0045944(positive regulation of transcription by RNA polymerase II);GO:0046966(thyroid hormone receptor binding);GO:0061630(ubiquitin protein ligase activity);GO:0070847(core mediator complex)","04919(Thyroid hormone signaling pathway)","K15133","NA","mediator complex subunit 17 [Source:HGNC Symbol;Acc:HGNC:2375]",{"v":1.489309,"d":"1.49"},{"v":1.479679,"d":"1.48"},0,0,0,0,"inf","inf",{"v":0.000104641079512598,"d":"0.00"},{"v":0.0108617440534077,"d":"0.01"},"up","yes"]
[201274,0,"chrX","-",2934816,2964270,"ENST00000381134",11,1853,"ENSG00000157399","ARSE","GO:0001501(skeletal system development);GO:0003824(catalytic activity);GO:0004065(arylsulfatase activity);GO:0005788(endoplasmic reticulum lumen);GO:0005794(Golgi apparatus);GO:0005795(Golgi stack);GO:0008484(sulfuric ester hydrolase activity);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016787(hydrolase activity);GO:0046872(metal ion binding);GO:0070062(extracellular exosome)","NA","NA","NA","arylsulfatase E [Source:HGNC Symbol;Acc:HGNC:719]",{"v":0.017319,"d":"0.02"},{"v":0.029694,"d":"0.03"},{"v":0.025565,"d":"0.03"},{"v":0.041827,"d":"0.04"},{"v":4.076678,"d":"4.08"},{"v":2.352044,"d":"2.35"},{"v":0.011216668013796,"d":"0.01"},{"v":-6.47821201239163,"d":"-6.48"},{"v":0.000106698632886259,"d":"0.00"},{"v":0.0110437644807914,"d":"0.01"},"down","yes"]
[37447,0,"chr11","-",122028366,122100492,"ENST00000532319",4,3003,"ENSG00000255248","MIR100HG","NA","NA","NA","NA","mir-100-let-7a-2-mir-125b-1 cluster host gene [Source:HGNC Symbol;Acc:HGNC:39522]",0,0,0,{"v":0.644492,"d":"0.64"},{"v":0.006389,"d":"0.01"},{"v":0.612109,"d":"0.61"},"-inf","-inf",{"v":0.000108430857224651,"d":"0.00"},{"v":0.0111911734175329,"d":"0.01"},"down","yes"]
[111542,0,"chr2","-",38295903,38377262,"ENST00000651368",12,1600,"ENSG00000119787","ATL2","GO:0000166(nucleotide binding);GO:0003924(GTPase activity);GO:0005515(protein binding);GO:0005525(GTP binding);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0007029(endoplasmic reticulum organization);GO:0007030(Golgi organization);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016787(hydrolase activity);GO:0042802(identical protein binding);GO:0051260(protein homooligomerization);GO:0098826(endoplasmic reticulum tubular network membrane);GO:1990809(endoplasmic reticulum tubular network membrane organization)","NA","K17339","EC:3.6.5.-","atlastin GTPase 2 [Source:HGNC Symbol;Acc:HGNC:24047]",0,{"v":3.123673,"d":"3.12"},{"v":3.518361,"d":"3.52"},{"v":0.000188,"d":"0.00"},0,{"v":0.000123,"d":"0.00"},{"v":21357.0225080386,"d":"21357.02"},{"v":14.3824229070848,"d":"14.38"},{"v":0.000109021953217396,"d":"0.00"},{"v":0.0112203047036487,"d":"0.01"},"up","yes"]
[72383,0,"chr16","+",20806521,20849665,"ENST00000348433",19,2604,"ENSG00000005189","REXO5","GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0004518(nuclease activity);GO:0004527(exonuclease activity);GO:0005730(nucleolus);GO:0016787(hydrolase activity);GO:0070062(extracellular exosome);GO:0090305(nucleic acid phosphodiester bond hydrolysis)","03008(Ribosome biogenesis in eukaryotes)","K14570","EC:3.1.-.-","RNA exonuclease 5 [Source:HGNC Symbol;Acc:HGNC:24661]",0,0,0,{"v":0.347944,"d":"0.35"},{"v":0.075982,"d":"0.08"},{"v":0.347864,"d":"0.35"},"-inf","-inf",{"v":0.000112493587344226,"d":"0.00"},{"v":0.0115448927350727,"d":"0.01"},"down","yes"]
[102281,0,"chr19","+",34677717,34686332,"ENST00000446502",6,2635,"ENSG00000089335","ZNF302","GO:0000981(DNA-binding transcription factor activity, RNA polymerase II-specific);GO:0003676(nucleic acid binding);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0005622(intracellular);GO:0005634(nucleus);GO:0006355(regulation of transcription, DNA-templated);GO:0006357(regulation of transcription by RNA polymerase II);GO:0046872(metal ion binding)","05168(Herpes simplex virus 1 infection)","K09228","NA","zinc finger protein 302 [Source:HGNC Symbol;Acc:HGNC:13848]",{"v":0.03161,"d":"0.03"},{"v":0.024771,"d":"0.02"},{"v":0.037458,"d":"0.04"},{"v":1.959263,"d":"1.96"},{"v":3.292977,"d":"3.29"},{"v":0.08044,"d":"0.08"},{"v":0.0175969681285958,"d":"0.02"},{"v":-5.82852930878902,"d":"-5.83"},{"v":0.000114156083742436,"d":"0.00"},{"v":0.0116825085136977,"d":"0.01"},"down","yes"]
[44994,0,"chr12","-",58872149,58919546,"ENST00000379141",19,3667,"ENSG00000139263","LRIG3","GO:0005515(protein binding);GO:0005615(extracellular space);GO:0005886(plasma membrane);GO:0007275(multicellular organism development);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0030659(cytoplasmic vesicle membrane);GO:0031012(extracellular matrix);GO:0031410(cytoplasmic vesicle);GO:0032474(otolith morphogenesis)","NA","NA","NA","leucine rich repeats and immunoglobulin like domains 3 [Source:HGNC Symbol;Acc:HGNC:30991]",{"v":6.924822,"d":"6.92"},0,{"v":6.913192,"d":"6.91"},{"v":0.021991,"d":"0.02"},{"v":0.004993,"d":"0.00"},0,{"v":512.822932107916,"d":"512.82"},{"v":9.00231696674433,"d":"9.00"},{"v":0.000115172159769877,"d":"0.00"},{"v":0.0117533836079765,"d":"0.01"},"up","yes"]
[199889,0,"chr9","-",129895812,130043167,"ENST00000355681",16,1977,"ENSG00000187239","FNBP1","GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0005764(lysosome);GO:0005829(cytosol);GO:0005856(cytoskeleton);GO:0005886(plasma membrane);GO:0005905(clathrin-coated pit);GO:0005938(cell cortex);GO:0006897(endocytosis);GO:0008289(lipid binding);GO:0016020(membrane);GO:0031410(cytoplasmic vesicle);GO:0042802(identical protein binding);GO:0061024(membrane organization)","NA","K20121","NA","formin binding protein 1 [Source:HGNC Symbol;Acc:HGNC:17069]",0,0,{"v":0.004679,"d":"0.00"},{"v":1.969827,"d":"1.97"},{"v":2.100637,"d":"2.10"},0,{"v":0.00114950040093709,"d":"0.00"},{"v":-9.76477731540473,"d":"-9.76"},{"v":0.000116759131940439,"d":"0.00"},{"v":0.0118819587209976,"d":"0.01"},"down","yes"]
[161950,0,"chr5","+",119452753,119542332,"ENST00000643250",24,2551,"ENSG00000133835","HSD17B4","GO:0000038(very long-chain fatty acid metabolic process);GO:0001649(osteoblast differentiation);GO:0003857(3-hydroxyacyl-CoA dehydrogenase activity);GO:0005102(signaling receptor binding);GO:0005777(peroxisome);GO:0005778(peroxisomal membrane);GO:0005782(peroxisomal matrix);GO:0005829(cytosol);GO:0006625(protein targeting to peroxisome);GO:0006629(lipid metabolic process);GO:0006631(fatty acid metabolic process);GO:0006635(fatty acid beta-oxidation);GO:0006699(bile acid biosynthetic process);GO:0008209(androgen metabolic process);GO:0008210(estrogen metabolic process);GO:0016020(membrane);GO:0016491(oxidoreductase activity);GO:0016508(long-chain-enoyl-CoA hydratase activity);GO:0016829(lyase activity);GO:0016853(isomerase activity);GO:0033540(fatty acid beta-oxidation using acyl-CoA oxidase);GO:0033989(3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA hydratase activity);GO:0036109(alpha-linolenic acid metabolic process);GO:0036111(very long-chain fatty-acyl-CoA metabolic process);GO:0036112(medium-chain fatty-acyl-CoA metabolic process);GO:0042803(protein homodimerization activity);GO:0044594(17-beta-hydroxysteroid dehydrogenase (NAD+) activity);GO:0055114(oxidation-reduction process);GO:0060009(Sertoli cell development)","00120(Primary bile acid biosynthesis);01040(Biosynthesis of unsaturated fatty acids);04146(Peroxisome)","K12405","4.2.1.107;4.2.1.119;EC:1.1.1.-","hydroxysteroid 17-beta dehydrogenase 4 [Source:HGNC Symbol;Acc:HGNC:5213]",{"v":1.204394,"d":"1.20"},{"v":1.147278,"d":"1.15"},0,0,0,0,"inf","inf",{"v":0.000117282113979537,"d":"0.00"},{"v":0.0119018413432306,"d":"0.01"},"up","yes"]
[26607,0,"chr11","+",4094843,4138875,"ENST00000533349",18,2863,"ENSG00000167325","RRM1","GO:0000166(nucleotide binding);GO:0000278(mitotic cell cycle);GO:0003824(catalytic activity);GO:0004748(ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor);GO:0005515(protein binding);GO:0005524(ATP binding);GO:0005635(nuclear envelope);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005971(ribonucleoside-diphosphate reductase complex);GO:0006206(pyrimidine nucleobase metabolic process);GO:0006260(DNA replication);GO:0008152(metabolic process);GO:0008584(male gonad development);GO:0009263(deoxyribonucleotide biosynthetic process);GO:0010212(response to ionizing radiation);GO:0015949(nucleobase-containing small molecule interconversion);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016491(oxidoreductase activity);GO:0017076(purine nucleotide binding);GO:0021846(cell proliferation in forebrain);GO:0042802(identical protein binding);GO:0042995(cell projection);GO:0043025(neuronal cell body);GO:0051259(protein complex oligomerization);GO:0051290(protein heterotetramerization);GO:0055114(oxidation-reduction process);GO:0060041(retina development in camera-type eye);GO:0097718(disordered domain specific binding)","00230(Purine metabolism);00240(Pyrimidine metabolism);00480(Glutathione metabolism);00983(Drug metabolism - other enzymes)","K10807","EC:1.17.4.1","ribonucleotide reductase catalytic subunit M1 [Source:HGNC Symbol;Acc:HGNC:10451]",{"v":0.366431,"d":"0.37"},{"v":1.850916,"d":"1.85"},0,0,0,0,"inf","inf",{"v":0.000119116335383449,"d":"0.00"},{"v":0.0120543077005033,"d":"0.01"},"up","yes"]
[73388,0,"chr16","-",29484690,29505820,"ENST00000550665",8,1861,"ENSG00000169203","NPIPB12","GO:0005654(nucleoplasm);GO:0016020(membrane);GO:0016021(integral component of membrane)","NA","NA","NA","nuclear pore complex interacting protein family, member B12 [Source:HGNC Symbol;Acc:HGNC:37491]",{"v":0.773294,"d":"0.77"},{"v":0.822823,"d":"0.82"},{"v":0.96019,"d":"0.96"},0,{"v":0.019834,"d":"0.02"},0,{"v":128.885096299284,"d":"128.89"},{"v":7.00994163626533,"d":"7.01"},{"v":0.000120214517241187,"d":"0.00"},{"v":0.0121316483649232,"d":"0.01"},"up","yes"]
[187018,0,"chr8","-",18057048,18084980,"ENST00000636455",13,1777,"ENSG00000104763","ASAH1","GO:0005576(extracellular region);GO:0005615(extracellular space);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005764(lysosome);GO:0006629(lipid metabolic process);GO:0006665(sphingolipid metabolic process);GO:0006687(glycosphingolipid metabolic process);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016787(hydrolase activity);GO:0016810(hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds);GO:0016811(hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides);GO:0017040(N-acylsphingosine amidohydrolase activity);GO:0030216(keratinocyte differentiation);GO:0043202(lysosomal lumen);GO:0043312(neutrophil degranulation);GO:0046512(sphingosine biosynthetic process);GO:0046513(ceramide biosynthetic process);GO:0046514(ceramide catabolic process);GO:0050810(regulation of steroid biosynthetic process);GO:0062098(regulation of programmed necrotic cell death);GO:0070062(extracellular exosome);GO:0071356(cellular response to tumor necrosis factor);GO:0102121(ceramidase activity);GO:1904724(tertiary granule lumen);GO:1904813(ficolin-1-rich granule lumen)","00600(Sphingolipid metabolism);04071(Sphingolipid signaling pathway);04142(Lysosome)","NA","NA","N-acylsphingosine amidohydrolase 1 [Source:HGNC Symbol;Acc:HGNC:735]",0,0,0,{"v":2.699636,"d":"2.70"},{"v":0.697356,"d":"0.70"},0,"-inf","-inf",{"v":0.000123262370079312,"d":"0.00"},{"v":0.0124047698198931,"d":"0.01"},"down","yes"]
[139830,0,"chr3","-",49108050,49120808,"ENST00000417901",27,4706,"ENSG00000172046","USP19","GO:0004843(thiol-dependent ubiquitin-specific protease activity);GO:0005515(protein binding);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005829(cytosol);GO:0006508(proteolysis);GO:0006511(ubiquitin-dependent protein catabolic process);GO:0008233(peptidase activity);GO:0008234(cysteine-type peptidase activity);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016579(protein deubiquitination);GO:0016787(hydrolase activity);GO:0030433(ubiquitin-dependent ERAD pathway);GO:0031625(ubiquitin protein ligase binding);GO:0031647(regulation of protein stability);GO:0034976(response to endoplasmic reticulum stress);GO:0036459(thiol-dependent ubiquitinyl hydrolase activity);GO:0046872(metal ion binding);GO:0048642(negative regulation of skeletal muscle tissue development);GO:0050821(protein stabilization);GO:0051879(Hsp90 protein binding);GO:0071108(protein K48-linked deubiquitination);GO:0090068(positive regulation of cell cycle process);GO:1900037(regulation of cellular response to hypoxia);GO:1901799(negative regulation of proteasomal protein catabolic process);GO:1904292(regulation of ERAD pathway);GO:1990380(Lys48-specific deubiquitinase activity)","NA","K11847","EC:3.4.19.12","ubiquitin specific peptidase 19 [Source:HGNC Symbol;Acc:HGNC:12617]",{"v":0.037554,"d":"0.04"},{"v":0.26615,"d":"0.27"},{"v":0.218637,"d":"0.22"},{"v":4.553484,"d":"4.55"},{"v":0.50002,"d":"0.50"},{"v":8.82242,"d":"8.82"},{"v":0.0376436913318349,"d":"0.04"},{"v":-4.73144808442302,"d":"-4.73"},{"v":0.000123666873195818,"d":"0.00"},{"v":0.0124110980751493,"d":"0.01"},"down","yes"]
[39128,0,"chr12","-",6556871,6568282,"ENST00000545200",17,2751,"ENSG00000111641","NOP2","GO:0000027(ribosomal large subunit assembly);GO:0003723(RNA binding);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005730(nucleolus);GO:0006357(regulation of transcription by RNA polymerase II);GO:0006364(rRNA processing);GO:0008168(methyltransferase activity);GO:0008284(positive regulation of cell population proliferation);GO:0008757(S-adenosylmethionine-dependent methyltransferase activity);GO:0009383(rRNA (cytosine-C5-)-methyltransferase activity);GO:0016740(transferase activity);GO:0032259(methylation);GO:0042254(ribosome biogenesis);GO:0070475(rRNA base methylation);GO:1901796(regulation of signal transduction by p53 class mediator)","NA","K14835","EC:2.1.1.310","NOP2 nucleolar protein [Source:HGNC Symbol;Acc:HGNC:7867]",0,0,0,{"v":0.325763,"d":"0.33"},{"v":0.023283,"d":"0.02"},{"v":0.754632,"d":"0.75"},"-inf","-inf",{"v":0.000124741545729369,"d":"0.00"},{"v":0.0124844637915922,"d":"0.01"},"down","yes"]
[58279,0,"chr14","+",73569285,73575658,"ENST00000613168",3,1553,"ENSG00000119673","ACOT2","GO:0000038(very long-chain fatty acid metabolic process);GO:0001676(long-chain fatty acid metabolic process);GO:0005102(signaling receptor binding);GO:0005515(protein binding);GO:0005739(mitochondrion);GO:0005759(mitochondrial matrix);GO:0005782(peroxisomal matrix);GO:0005829(cytosol);GO:0006625(protein targeting to peroxisome);GO:0006631(fatty acid metabolic process);GO:0006637(acyl-CoA metabolic process);GO:0016290(palmitoyl-CoA hydrolase activity);GO:0016787(hydrolase activity);GO:0016790(thiolester hydrolase activity);GO:0047617(acyl-CoA hydrolase activity);GO:0052689(carboxylic ester hydrolase activity);GO:0102991(myristoyl-CoA hydrolase activity)","00062(Fatty acid elongation);01040(Biosynthesis of unsaturated fatty acids);04913(Ovarian steroidogenesis)","K01068","EC:3.1.2.2","acyl-CoA thioesterase 2 [Source:HGNC Symbol;Acc:HGNC:18431]",{"v":0.585259,"d":"0.59"},{"v":0.842757,"d":"0.84"},{"v":0.661588,"d":"0.66"},{"v":22.658499,"d":"22.66"},{"v":25.351484,"d":"25.35"},{"v":0.756637,"d":"0.76"},{"v":0.0428490635602796,"d":"0.04"},{"v":-4.54459251429817,"d":"-4.54"},{"v":0.000125377954543258,"d":"0.00"},{"v":0.0125136843092213,"d":"0.01"},"down","yes"]
[13775,0,"chr1","-",168090446,168104909,"ENST00000493800",3,1381,"ENSG00000143147","GPR161","GO:0004930(G protein-coupled receptor activity);GO:0005886(plasma membrane);GO:0005929(cilium);GO:0007165(signal transduction);GO:0007186(G protein-coupled receptor signaling pathway);GO:0007189(adenylate cyclase-activating G protein-coupled receptor signaling pathway);GO:0007275(multicellular organism development);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0030666(endocytic vesicle membrane);GO:0042995(cell projection);GO:0055037(recycling endosome);GO:0060170(ciliary membrane);GO:1901621(negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning)","04340(Hedgehog signaling pathway)","K08439","NA","G protein-coupled receptor 161 [Source:HGNC Symbol;Acc:HGNC:23694]",{"v":0.033422,"d":"0.03"},{"v":0.055144,"d":"0.06"},{"v":0.014835,"d":"0.01"},{"v":0.359992,"d":"0.36"},{"v":2.812024,"d":"2.81"},{"v":1.257325,"d":"1.26"},{"v":0.0233445562217946,"d":"0.02"},{"v":-5.42077002645492,"d":"-5.42"},{"v":0.000127734230529011,"d":"0.00"},{"v":0.0126984912559761,"d":"0.01"},"down","yes"]
[202366,0,"chrX","-",40051248,40177329,"ENST00000342274",15,6390,"ENSG00000183337","BCOR","GO:0000122(negative regulation of transcription by RNA polymerase II);GO:0000415(negative regulation of histone H3-K36 methylation);GO:0000977(RNA polymerase II regulatory region sequence-specific DNA binding);GO:0001835(blastocyst hatching);GO:0003714(transcription corepressor activity);GO:0004842(ubiquitin-protein transferase activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0006325(chromatin organization);GO:0007507(heart development);GO:0008134(transcription factor binding);GO:0030502(negative regulation of bone mineralization);GO:0031072(heat shock protein binding);GO:0035518(histone H2A monoubiquitination);GO:0042476(odontogenesis);GO:0042826(histone deacetylase binding);GO:0044212(transcription regulatory region DNA binding);GO:0045892(negative regulation of transcription, DNA-templated);GO:0051572(negative regulation of histone H3-K4 methylation);GO:0060021(roof of mouth development);GO:0065001(specification of axis polarity);GO:0070171(negative regulation of tooth mineralization);GO:0140261(BCOR complex)","NA","K23215","NA","BCL6 corepressor [Source:HGNC Symbol;Acc:HGNC:20893]",{"v":0.268598,"d":"0.27"},0,{"v":0.681588,"d":"0.68"},0,0,0,"inf","inf",{"v":0.000127928648491254,"d":"0.00"},{"v":0.0126984912559761,"d":"0.01"},"up","yes"]
[112425,0,"chr2","-",54972187,55010449,"ENST00000394609",7,1898,"ENSG00000115310","RTN4","GO:0001825(blastocyst formation);GO:0003723(RNA binding);GO:0005515(protein binding);GO:0005635(nuclear envelope);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005886(plasma membrane);GO:0006915(apoptotic process);GO:0007399(nervous system development);GO:0007413(axonal fasciculation);GO:0010634(positive regulation of epithelial cell migration);GO:0014069(postsynaptic density);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0021801(cerebral cortex radial glia guided migration);GO:0030054(cell junction);GO:0030176(integral component of endoplasmic reticulum membrane);GO:0030308(negative regulation of cell growth);GO:0030517(negative regulation of axon extension);GO:0031625(ubiquitin protein ligase binding);GO:0033601(positive regulation of mammary gland epithelial cell proliferation);GO:0034165(positive regulation of toll-like receptor 9 signaling pathway);GO:0042981(regulation of apoptotic process);GO:0042995(cell projection);GO:0043025(neuronal cell body);GO:0045296(cadherin binding);GO:0050771(negative regulation of axonogenesis);GO:0050821(protein stabilization);GO:0051292(nuclear pore complex assembly);GO:0051897(positive regulation of protein kinase B signaling);GO:0051960(regulation of nervous system development);GO:0060317(cardiac epithelial to mesenchymal transition);GO:0061462(protein localization to lysosome);GO:0071782(endoplasmic reticulum tubular network);GO:0071786(endoplasmic reticulum tubular network organization);GO:0071787(endoplasmic reticulum tubular network formation);GO:0090156(cellular sphingolipid homeostasis);GO:0098826(endoplasmic reticulum tubular network membrane);GO:1905552(positive regulation of protein localization to endoplasmic reticulum);GO:1905580(positive regulation of ERBB3 signaling pathway);GO:1990809(endoplasmic reticulum tubular network membrane organization);GO:2000172(regulation of branching morphogenesis of a nerve)","05010(Alzheimer disease)","K20720","NA","reticulon 4 [Source:HGNC Symbol;Acc:HGNC:14085]",{"v":0.272077,"d":"0.27"},{"v":0.000979,"d":"0.00"},{"v":0.509374,"d":"0.51"},{"v":3.32018,"d":"3.32"},{"v":0.243487,"d":"0.24"},{"v":106.927055,"d":"106.93"},{"v":0.00708140906165859,"d":"0.01"},{"v":-7.14174782774288,"d":"-7.14"},{"v":0.000129576359390428,"d":"0.00"},{"v":0.0128270003723549,"d":"0.01"},"down","yes"]
[87595,0,"chr17","-",50190309,50190924,"ENST00000494334",2,396,"ENSG00000108821","COL1A1","GO:0001501(skeletal system development);GO:0001503(ossification);GO:0001568(blood vessel development);GO:0001649(osteoblast differentiation);GO:0001957(intramembranous ossification);GO:0001958(endochondral ossification);GO:0002020(protease binding);GO:0005201(extracellular matrix structural constituent);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0005581(collagen trimer);GO:0005584(collagen type I trimer);GO:0005615(extracellular space);GO:0005737(cytoplasm);GO:0005783(endoplasmic reticulum);GO:0005788(endoplasmic reticulum lumen);GO:0005794(Golgi apparatus);GO:0007584(response to nutrient);GO:0007596(blood coagulation);GO:0007601(visual perception);GO:0007605(sensory perception of sound);GO:0009612(response to mechanical stimulus);GO:0010718(positive regulation of epithelial to mesenchymal transition);GO:0010812(negative regulation of cell-substrate adhesion);GO:0015031(protein transport);GO:0030020(extracellular matrix structural constituent conferring tensile strength);GO:0030141(secretory granule);GO:0030168(platelet activation);GO:0030198(extracellular matrix organization);GO:0030199(collagen fibril organization);GO:0030335(positive regulation of cell migration);GO:0031012(extracellular matrix);GO:0031667(response to nutrient levels);GO:0031960(response to corticosteroid);GO:0032355(response to estradiol);GO:0032964(collagen biosynthetic process);GO:0034504(protein localization to nucleus);GO:0034505(tooth mineralization);GO:0038063(collagen-activated tyrosine kinase receptor signaling pathway);GO:0042060(wound healing);GO:0042493(response to drug);GO:0042542(response to hydrogen peroxide);GO:0042802(identical protein binding);GO:0043434(response to peptide hormone);GO:0043588(skin development);GO:0043589(skin morphogenesis);GO:0044344(cellular response to fibroblast growth factor stimulus);GO:0044691(tooth eruption);GO:0045893(positive regulation of transcription, DNA-templated);GO:0046872(metal ion binding);GO:0048407(platelet-derived growth factor binding);GO:0048545(response to steroid hormone);GO:0048705(skeletal system morphogenesis);GO:0048706(embryonic skeletal system development);GO:0050776(regulation of immune response);GO:0050900(leukocyte migration);GO:0051591(response to cAMP);GO:0055093(response to hyperoxia);GO:0060325(face morphogenesis);GO:0060346(bone trabecula formation);GO:0060351(cartilage development involved in endochondral bone morphogenesis);GO:0062023(collagen-containing extracellular matrix);GO:0070208(protein heterotrimerization);GO:0071230(cellular response to amino acid stimulus);GO:0071260(cellular response to mechanical stimulus);GO:0071300(cellular response to retinoic acid);GO:0071306(cellular response to vitamin E);GO:0071356(cellular response to tumor necrosis factor);GO:0071364(cellular response to epidermal growth factor stimulus);GO:0071560(cellular response to transforming growth factor beta stimulus);GO:0090263(positive regulation of canonical Wnt signaling pathway);GO:1902617(response to fluoride);GO:1902618(cellular response to fluoride)","04151(PI3K-Akt signaling pathway);04510(Focal adhesion);04512(ECM-receptor interaction);04611(Platelet activation);04926(Relaxin signaling pathway);04933(AGE-RAGE signaling pathway in diabetic complications);04974(Protein digestion and absorption);05146(Amoebiasis);05165(Human papillomavirus infection)","K06236","NA","collagen type I alpha 1 chain [Source:HGNC Symbol;Acc:HGNC:2197]",{"v":0.834423,"d":"0.83"},{"v":2.706926,"d":"2.71"},{"v":3.364197,"d":"3.36"},{"v":1.136445,"d":"1.14"},{"v":1251.177246,"d":"1251.18"},{"v":1.809858,"d":"1.81"},{"v":0.005506272492456,"d":"0.01"},{"v":-7.50470827738255,"d":"-7.50"},{"v":0.000135293347524934,"d":"0.00"},{"v":0.0133249006921102,"d":"0.01"},"down","yes"]
[88611,0,"chr17","+",60679458,61392831,"ENST00000588462",25,3559,"ENSG00000141376","BCAS3","GO:0001525(angiogenesis);GO:0003682(chromatin binding);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005730(nucleolus);GO:0005737(cytoplasm);GO:0005856(cytoskeleton);GO:0005881(cytoplasmic microtubule);GO:0007030(Golgi organization);GO:0008134(transcription factor binding);GO:0010595(positive regulation of endothelial cell migration);GO:0010698(acetyltransferase activator activity);GO:0031023(microtubule organizing center organization);GO:0031252(cell leading edge);GO:0034260(negative regulation of GTPase activity);GO:0035035(histone acetyltransferase binding);GO:0035148(tube formation);GO:0035257(nuclear hormone receptor binding);GO:0035327(transcriptionally active chromatin);GO:0042393(histone binding);GO:0042594(response to starvation);GO:0043085(positive regulation of catalytic activity);GO:0043547(positive regulation of GTPase activity);GO:0045111(intermediate filament cytoskeleton);GO:0045944(positive regulation of transcription by RNA polymerase II);GO:0048487(beta-tubulin binding);GO:0051491(positive regulation of filopodium assembly);GO:0051895(negative regulation of focal adhesion assembly);GO:0071391(cellular response to estrogen stimulus);GO:0071944(cell periphery);GO:0090316(positive regulation of intracellular protein transport);GO:0090630(activation of GTPase activity);GO:2000114(regulation of establishment of cell polarity);GO:2000251(positive regulation of actin cytoskeleton reorganization)","NA","NA","NA","BCAS3, microtubule associated cell migration factor [Source:HGNC Symbol;Acc:HGNC:14347]",{"v":0.013626,"d":"0.01"},0,0,{"v":2.90928,"d":"2.91"},{"v":0.006,"d":"0.01"},{"v":2.039642,"d":"2.04"},{"v":0.00274999283540689,"d":"0.00"},{"v":-8.50635642469257,"d":"-8.51"},{"v":0.00013533961892069,"d":"0.00"},{"v":0.0133249006921102,"d":"0.01"},"down","yes"]
[75306,0,"chr16","+",57020713,57083519,"ENST00000539144",46,6505,"ENSG00000140853","NLRC5","GO:0000166(nucleotide binding);GO:0000978(RNA polymerase II proximal promoter sequence-specific DNA binding);GO:0002376(immune system process);GO:0005515(protein binding);GO:0005524(ATP binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005813(centrosome);GO:0005829(cytosol);GO:0009617(response to bacterium);GO:0032088(negative regulation of NF-kappaB transcription factor activity);GO:0032480(negative regulation of type I interferon production);GO:0035556(intracellular signal transduction);GO:0043549(regulation of kinase activity);GO:0045087(innate immune response);GO:0045345(positive regulation of MHC class I biosynthetic process);GO:0045944(positive regulation of transcription by RNA polymerase II);GO:0051607(defense response to virus);GO:0060335(positive regulation of interferon-gamma-mediated signaling pathway);GO:0060339(negative regulation of type I interferon-mediated signaling pathway);GO:0060340(positive regulation of type I interferon-mediated signaling pathway)","NA","K22615","NA","NLR family CARD domain containing 5 [Source:HGNC Symbol;Acc:HGNC:29933]",0,0,0,{"v":0.59649,"d":"0.60"},{"v":0.30171,"d":"0.30"},0,"-inf","-inf",{"v":0.000136335017940814,"d":"0.00"},{"v":0.0133518143753383,"d":"0.01"},"down","yes"]
[10744,0,"chr1","+",149390623,149556361,"ENST00000621744",97,14425,"ENSG00000286185","AC242842","GO:0005737(cytoplasm)","NA","NA","NA","Neuroblastoma breakpoint family member 19  [Source:UniProtKB/Swiss-Prot;Acc:A0A087WUL8]",{"v":0.019938,"d":"0.02"},{"v":0.046358,"d":"0.05"},{"v":0.006171,"d":"0.01"},{"v":0.027501,"d":"0.03"},{"v":1.77451,"d":"1.77"},{"v":1.722217,"d":"1.72"},{"v":0.0205625175215678,"d":"0.02"},{"v":-5.60383928158857,"d":"-5.60"},{"v":0.000136348008071855,"d":"0.00"},{"v":0.0133518143753383,"d":"0.01"},"down","yes"]
[137126,0,"chr3","+",14125015,14132921,"ENST00000432444",7,908,"ENSG00000170876","TMEM43","GO:0005515(protein binding);GO:0005634(nucleus);GO:0005637(nuclear inner membrane);GO:0005639(integral component of nuclear inner membrane);GO:0005783(endoplasmic reticulum);GO:0005788(endoplasmic reticulum lumen);GO:0005794(Golgi apparatus);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0043621(protein self-association);GO:0071763(nuclear membrane organization)","NA","NA","NA","transmembrane protein 43 [Source:HGNC Symbol;Acc:HGNC:28472]",0,{"v":0.007219,"d":"0.01"},{"v":0.076982,"d":"0.08"},{"v":4.545974,"d":"4.55"},{"v":4.858909,"d":"4.86"},{"v":0.110954,"d":"0.11"},{"v":0.00884851222230898,"d":"0.01"},{"v":-6.82034938200136,"d":"-6.82"},{"v":0.000145821994976212,"d":"0.00"},{"v":0.0142411641867897,"d":"0.01"},"down","yes"]
[52081,0,"chr13","-",52132644,52159535,"ENST00000618534",16,2414,"ENSG00000136098","NEK3","GO:0000166(nucleotide binding);GO:0000278(mitotic cell cycle);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005515(protein binding);GO:0005524(ATP binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0006468(protein phosphorylation);GO:0007049(cell cycle);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0016740(transferase activity);GO:0030010(establishment of cell polarity);GO:0030424(axon);GO:0042995(cell projection);GO:0046872(metal ion binding);GO:0048812(neuron projection morphogenesis);GO:0051301(cell division);GO:0090043(regulation of tubulin deacetylation)","NA","K20873","EC:2.7.11.1","NIMA related kinase 3 [Source:HGNC Symbol;Acc:HGNC:7746]",{"v":1.960635,"d":"1.96"},{"v":0.082244,"d":"0.08"},{"v":3.358926,"d":"3.36"},{"v":0.045488,"d":"0.05"},{"v":0.025357,"d":"0.03"},{"v":0.030469,"d":"0.03"},{"v":53.3174585940739,"d":"53.32"},{"v":5.73653611010218,"d":"5.74"},{"v":0.000148690788226129,"d":"0.00"},{"v":0.0144824030462608,"d":"0.01"},"up","yes"]
[42236,0,"chr12","-",48337180,48350771,"ENST00000544117",6,7819,"ENSG00000167528","ZNF641","GO:0000981(DNA-binding transcription factor activity, RNA polymerase II-specific);GO:0003676(nucleic acid binding);GO:0003677(DNA binding);GO:0005622(intracellular);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0006355(regulation of transcription, DNA-templated);GO:0006357(regulation of transcription by RNA polymerase II);GO:0046872(metal ion binding)","05168(Herpes simplex virus 1 infection)","K09228","NA","zinc finger protein 641 [Source:HGNC Symbol;Acc:HGNC:31834]",{"v":0.00537,"d":"0.01"},{"v":0.008334,"d":"0.01"},{"v":0.025107,"d":"0.03"},{"v":0.55368,"d":"0.55"},{"v":1.956762,"d":"1.96"},{"v":0.027258,"d":"0.03"},{"v":0.0152937699491666,"d":"0.02"},{"v":-6.03091211161996,"d":"-6.03"},{"v":0.000149382555261145,"d":"0.00"},{"v":0.0145108776273727,"d":"0.01"},"down","yes"]
[143388,0,"chr3","-",121663203,121749767,"ENST00000614479",21,11115,"ENSG00000173230","GOLGB1","GO:0000139(Golgi membrane);GO:0003700(DNA-binding transcription factor activity);GO:0003723(RNA binding);GO:0005515(protein binding);GO:0005793(endoplasmic reticulum-Golgi intermediate compartment);GO:0005794(Golgi apparatus);GO:0005795(Golgi stack);GO:0005801(cis-Golgi network);GO:0006355(regulation of transcription, DNA-templated);GO:0006888(endoplasmic reticulum to Golgi vesicle-mediated transport);GO:0007030(Golgi organization);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0043565(sequence-specific DNA binding);GO:1905793(protein localization to pericentriolar material)","NA","K20478","NA","golgin B1 [Source:HGNC Symbol;Acc:HGNC:4429]",{"v":1.761687,"d":"1.76"},{"v":4.340477,"d":"4.34"},{"v":1.351598,"d":"1.35"},{"v":0.046803,"d":"0.05"},{"v":0.315946,"d":"0.32"},{"v":0.034243,"d":"0.03"},{"v":18.7755974931485,"d":"18.78"},{"v":4.23078691403498,"d":"4.23"},{"v":0.000150728137275149,"d":"0.00"},{"v":0.0146025419392164,"d":"0.01"},"up","yes"]
[55021,0,"chr14","+",24098512,24102830,"ENST00000559503",5,826,"ENSG00000100889","PCK2","GO:0000166(nucleotide binding);GO:0004611(phosphoenolpyruvate carboxykinase activity);GO:0004613(phosphoenolpyruvate carboxykinase (GTP) activity);GO:0005515(protein binding);GO:0005525(GTP binding);GO:0005739(mitochondrion);GO:0005759(mitochondrial matrix);GO:0005829(cytosol);GO:0006090(pyruvate metabolic process);GO:0006094(gluconeogenesis);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0016829(lyase activity);GO:0016831(carboxy-lyase activity);GO:0017076(purine nucleotide binding);GO:0019543(propionate catabolic process);GO:0030145(manganese ion binding);GO:0032869(cellular response to insulin stimulus);GO:0033993(response to lipid);GO:0042594(response to starvation);GO:0046327(glycerol biosynthetic process from pyruvate);GO:0046872(metal ion binding);GO:0070365(hepatocyte differentiation);GO:0071333(cellular response to glucose stimulus);GO:0071549(cellular response to dexamethasone stimulus)","00010(Glycolysis / Gluconeogenesis);00020(Citrate cycle (TCA cycle));00620(Pyruvate metabolism);03320(PPAR signaling pathway);04068(FoxO signaling pathway);04151(PI3K-Akt signaling pathway);04152(AMPK signaling pathway);04910(Insulin signaling pathway);04920(Adipocytokine signaling pathway);04922(Glucagon signaling pathway);04931(Insulin resistance);04964(Proximal tubule bicarbonate reclamation)","NA","NA","phosphoenolpyruvate carboxykinase 2, mitochondrial [Source:HGNC Symbol;Acc:HGNC:8725]",0,{"v":0.050894,"d":"0.05"},0,{"v":8.044189,"d":"8.04"},{"v":4.608562,"d":"4.61"},{"v":0.037903,"d":"0.04"},{"v":0.00401035281554442,"d":"0.00"},{"v":-7.96205511959151,"d":"-7.96"},{"v":0.000152077697649726,"d":"0.00"},{"v":0.0146928532995478,"d":"0.01"},"down","yes"]
[154525,0,"chr4","-",121668027,121696966,"ENST00000506395",13,1606,"ENSG00000164111","ANXA5","GO:0002576(platelet degranulation);GO:0004859(phospholipase inhibitor activity);GO:0005388(calcium-transporting ATPase activity);GO:0005509(calcium ion binding);GO:0005515(protein binding);GO:0005543(phospholipid binding);GO:0005544(calcium-dependent phospholipid binding);GO:0005576(extracellular region);GO:0005622(intracellular);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005925(focal adhesion);GO:0007165(signal transduction);GO:0007596(blood coagulation);GO:0007599(hemostasis);GO:0008201(heparin binding);GO:0009897(external side of plasma membrane);GO:0010033(response to organic substance);GO:0016020(membrane);GO:0017046(peptide hormone binding);GO:0030195(negative regulation of blood coagulation);GO:0030971(receptor tyrosine kinase binding);GO:0043065(positive regulation of apoptotic process);GO:0043066(negative regulation of apoptotic process);GO:0043086(negative regulation of catalytic activity);GO:0050819(negative regulation of coagulation);GO:0051260(protein homooligomerization);GO:0051283(negative regulation of sequestering of calcium ion);GO:0051592(response to calcium ion);GO:0060090(molecular adaptor activity);GO:0062023(collagen-containing extracellular matrix);GO:0070062(extracellular exosome);GO:0070588(calcium ion transmembrane transport);GO:0071284(cellular response to lead ion);GO:0072563(endothelial microparticle);GO:0097066(response to thyroid hormone);GO:0097211(cellular response to gonadotropin-releasing hormone);GO:0099132(ATP hydrolysis coupled cation transmembrane transport);GO:1901317(regulation of flagellated sperm motility);GO:1902721(negative regulation of prolactin secretion)","NA","NA","NA","annexin A5 [Source:HGNC Symbol;Acc:HGNC:543]",{"v":17.304123,"d":"17.30"},{"v":18.546913,"d":"18.55"},{"v":135.834213,"d":"135.83"},{"v":6.052467,"d":"6.05"},{"v":4.012341,"d":"4.01"},{"v":4.446218,"d":"4.45"},{"v":11.83136526666,"d":"11.83"},{"v":3.56454465629051,"d":"3.56"},{"v":0.000152469190584352,"d":"0.00"},{"v":0.0146928532995478,"d":"0.01"},"up","yes"]
[8246,0,"chr1","+",92080305,92184725,"ENST00000635934",17,5944,"ENSG00000189195","BTBD8","GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0098793(presynapse);GO:0150007(clathrin-dependent synaptic vesicle endocytosis)","NA","K10480","NA","BTB domain containing 8 [Source:HGNC Symbol;Acc:HGNC:21019]",0,0,0,{"v":0.763241,"d":"0.76"},0,{"v":0.210345,"d":"0.21"},"-inf","-inf",{"v":0.000153487432124143,"d":"0.00"},{"v":0.0147282214576903,"d":"0.01"},"down","yes"]
[152041,0,"chr4","-",72280969,72569221,"ENST00000286657",22,6244,"ENSG00000156140","ADAMTS3","GO:0004175(endopeptidase activity);GO:0004222(metalloendopeptidase activity);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0005615(extracellular space);GO:0006508(proteolysis);GO:0008201(heparin binding);GO:0008233(peptidase activity);GO:0008237(metallopeptidase activity);GO:0008270(zinc ion binding);GO:0010573(vascular endothelial growth factor production);GO:0016485(protein processing);GO:0016787(hydrolase activity);GO:0030199(collagen fibril organization);GO:0030574(collagen catabolic process);GO:0031012(extracellular matrix);GO:0032964(collagen biosynthetic process);GO:0046872(metal ion binding);GO:0062023(collagen-containing extracellular matrix);GO:0070062(extracellular exosome);GO:0097435(supramolecular fiber organization);GO:1900748(positive regulation of vascular endothelial growth factor signaling pathway)","NA","K08619","EC:3.4.24.-","ADAM metallopeptidase with thrombospondin type 1 motif 3 [Source:HGNC Symbol;Acc:HGNC:219]",{"v":6.563369,"d":"6.56"},{"v":6.720691,"d":"6.72"},{"v":6.119771,"d":"6.12"},{"v":0.885789,"d":"0.89"},{"v":0.769765,"d":"0.77"},{"v":0.964686,"d":"0.96"},{"v":7.40536401245688,"d":"7.41"},{"v":2.88857065328036,"d":"2.89"},{"v":0.000153647011628533,"d":"0.00"},{"v":0.0147282214576903,"d":"0.01"},"up","yes"]
[135550,0,"chr22","+",45502883,45563352,"ENST00000402984",16,2355,"ENSG00000077942","FBLN1","GO:0001933(negative regulation of protein phosphorylation);GO:0001968(fibronectin binding);GO:0005201(extracellular matrix structural constituent);GO:0005509(calcium ion binding);GO:0005576(extracellular region);GO:0005604(basement membrane);GO:0005615(extracellular space);GO:0007162(negative regulation of cell adhesion);GO:0007566(embryo implantation);GO:0008022(protein C-terminus binding);GO:0010952(positive regulation of peptidase activity);GO:0016032(viral process);GO:0016504(peptidase activator activity);GO:0030198(extracellular matrix organization);GO:0031012(extracellular matrix);GO:0042802(identical protein binding);GO:0044877(protein-containing complex binding);GO:0062023(collagen-containing extracellular matrix);GO:0070051(fibrinogen binding);GO:0070062(extracellular exosome);GO:0070373(negative regulation of ERK1 and ERK2 cascade);GO:0071953(elastic fiber);GO:0072378(blood coagulation, fibrin clot formation);GO:1900025(negative regulation of substrate adhesion-dependent cell spreading);GO:2000146(negative regulation of cell motility);GO:2000647(negative regulation of stem cell proliferation)","NA","K17307","NA","fibulin 1 [Source:HGNC Symbol;Acc:HGNC:3600]",{"v":160.475311,"d":"160.48"},{"v":145.463837,"d":"145.46"},{"v":111.619247,"d":"111.62"},{"v":20.693653,"d":"20.69"},{"v":14.702583,"d":"14.70"},{"v":33.685955,"d":"33.69"},{"v":6.04437104491952,"d":"6.04"},{"v":2.59559222573019,"d":"2.60"},{"v":0.000157309837789066,"d":"0.00"},{"v":0.0150154738173556,"d":"0.02"},"up","yes"]
[7828,0,"chr1","+",84164382,84238494,"ENST00000610703",10,4240,"ENSG00000142875","PRKACB","GO:0000166(nucleotide binding);GO:0000287(magnesium ion binding);GO:0001843(neural tube closure);GO:0002223(stimulatory C-type lectin receptor signaling pathway);GO:0003091(renal water homeostasis);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0004691(cAMP-dependent protein kinase activity);GO:0005515(protein binding);GO:0005524(ATP binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0005813(centrosome);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0005952(cAMP-dependent protein kinase complex);GO:0006468(protein phosphorylation);GO:0007165(signal transduction);GO:0007186(G protein-coupled receptor signaling pathway);GO:0007188(adenylate cyclase-modulating G protein-coupled receptor signaling pathway);GO:0007596(blood coagulation);GO:0016020(membrane);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0016740(transferase activity);GO:0031625(ubiquitin protein ligase binding);GO:0034199(activation of protein kinase A activity);GO:0034237(protein kinase A regulatory subunit binding);GO:0034380(high-density lipoprotein particle assembly);GO:0045171(intercellular bridge);GO:0048471(perinuclear region of cytoplasm);GO:0051447(negative regulation of meiotic cell cycle);GO:0070062(extracellular exosome);GO:0070613(regulation of protein processing);GO:0071377(cellular response to glucagon stimulus);GO:0097338(response to clozapine);GO:0097546(ciliary base);GO:1901621(negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning)","01522(Endocrine resistance);04010(MAPK signaling pathway);04014(Ras signaling pathway);04020(Calcium signaling pathway);04024(cAMP signaling pathway);04062(Chemokine signaling pathway);04114(Oocyte meiosis);04140(Autophagy - animal);04211(Longevity regulating pathway);04213(Longevity regulating pathway - multiple species);04261(Adrenergic signaling in cardiomyocytes);04270(Vascular smooth muscle contraction);04310(Wnt signaling pathway);04340(Hedgehog signaling pathway);04371(Apelin signaling pathway);04530(Tight junction);04540(Gap junction);04611(Platelet activation);04713(Circadian entrainment);04714(Thermogenesis);04720(Long-term potentiation);04723(Retrograde endocannabinoid signaling);04724(Glutamatergic synapse);04725(Cholinergic synapse);04726(Serotonergic synapse);04727(GABAergic synapse);04728(Dopaminergic synapse);04740(Olfactory transduction);04742(Taste transduction);04750(Inflammatory mediator regulation of TRP channels);04910(Insulin signaling pathway);04911(Insulin secretion);04912(GnRH signaling pathway);04913(Ovarian steroidogenesis);04914(Progesterone-mediated oocyte maturation);04915(Estrogen signaling pathway);04916(Melanogenesis);04918(Thyroid hormone synthesis);04919(Thyroid hormone signaling pathway);04921(Oxytocin signaling pathway);04922(Glucagon signaling pathway);04923(Regulation of lipolysis in adipocytes);04924(Renin secretion);04925(Aldosterone synthesis and secretion);04926(Relaxin signaling pathway);04927(Cortisol synthesis and secretion);04928(Parathyroid hormone synthesis, secretion and action);04934(Cushing syndrome);04961(Endocrine and other factor-regulated calcium reabsorption);04962(Vasopressin-regulated water reabsorption);04970(Salivary secretion);04971(Gastric acid secretion);04976(Bile secretion);05012(Parkinson disease);05020(Prion diseases);05030(Cocaine addiction);05031(Amphetamine addiction);05032(Morphine addiction);05110(Vibrio cholerae infection);05146(Amoebiasis);05163(Human cytomegalovirus infection);05165(Human papillomavirus infection);05166(Human T-cell leukemia virus 1 infection);05200(Pathways in cancer);05203(Viral carcinogenesis);05205(Proteoglycans in cancer);05414(Dilated cardiomyopathy (DCM))","NA","NA","protein kinase cAMP-activated catalytic subunit beta [Source:HGNC Symbol;Acc:HGNC:9381]",0,{"v":0.196011,"d":"0.20"},{"v":0.152944,"d":"0.15"},{"v":1.791498,"d":"1.79"},{"v":4.735523,"d":"4.74"},{"v":8.361337,"d":"8.36"},{"v":0.0234381118455104,"d":"0.02"},{"v":-5.41499983762712,"d":"-5.41"},{"v":0.00015747028693676,"d":"0.00"},{"v":0.0150154738173556,"d":"0.02"},"down","yes"]
[185112,0,"chr7","+",148698645,148801025,"ENST00000602748",22,3054,"ENSG00000055130","CUL1","GO:0000082(G1/S transition of mitotic cell cycle);GO:0000086(G2/M transition of mitotic cell cycle);GO:0000209(protein polyubiquitination);GO:0002223(stimulatory C-type lectin receptor signaling pathway);GO:0005515(protein binding);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0006511(ubiquitin-dependent protein catabolic process);GO:0006513(protein monoubiquitination);GO:0006879(cellular iron ion homeostasis);GO:0006915(apoptotic process);GO:0007050(cell cycle arrest);GO:0008283(cell population proliferation);GO:0008285(negative regulation of cell population proliferation);GO:0009887(animal organ morphogenesis);GO:0010265(SCF complex assembly);GO:0010972(negative regulation of G2/M transition of mitotic cell cycle);GO:0016032(viral process);GO:0016055(Wnt signaling pathway);GO:0016567(protein ubiquitination);GO:0019005(SCF ubiquitin ligase complex);GO:0031146(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process);GO:0031461(cullin-RING ubiquitin ligase complex);GO:0031625(ubiquitin protein ligase binding);GO:0038061(NIK/NF-kappaB signaling);GO:0038095(Fc-epsilon receptor signaling pathway);GO:0043161(proteasome-mediated ubiquitin-dependent protein catabolic process);GO:0043687(post-translational protein modification);GO:0050852(T cell receptor signaling pathway);GO:0051403(stress-activated MAPK cascade);GO:0061630(ubiquitin protein ligase activity);GO:0070498(interleukin-1-mediated signaling pathway);GO:0097193(intrinsic apoptotic signaling pathway);GO:1901990(regulation of mitotic cell cycle phase transition);GO:1990452(Parkin-FBXW7-Cul1 ubiquitin ligase complex)","04110(Cell cycle);04114(Oocyte meiosis);04120(Ubiquitin mediated proteolysis);04141(Protein processing in endoplasmic reticulum);04310(Wnt signaling pathway);04340(Hedgehog signaling pathway);04350(TGF-beta signaling pathway);04710(Circadian rhythm);05170(Human immunodeficiency virus 1 infection);05200(Pathways in cancer)","NA","NA","cullin 1 [Source:HGNC Symbol;Acc:HGNC:2551]",{"v":0.014436,"d":"0.01"},0,0,{"v":4.540425,"d":"4.54"},{"v":4.641676,"d":"4.64"},0,{"v":0.00157218919722186,"d":"0.00"},{"v":-9.31300944272115,"d":"-9.31"},{"v":0.000164830996469649,"d":"0.00"},{"v":0.0156762044548229,"d":"0.02"},"down","yes"]
[112074,0,"chr2","-",46901874,46916054,"ENST00000409800",3,3955,"ENSG00000180398","MCFD2","GO:0000139(Golgi membrane);GO:0005509(calcium ion binding);GO:0005515(protein binding);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005793(endoplasmic reticulum-Golgi intermediate compartment);GO:0005794(Golgi apparatus);GO:0006888(endoplasmic reticulum to Golgi vesicle-mediated transport);GO:0012507(ER to Golgi transport vesicle membrane);GO:0015031(protein transport);GO:0016192(vesicle-mediated transport);GO:0018279(protein N-linked glycosylation via asparagine);GO:0033116(endoplasmic reticulum-Golgi intermediate compartment membrane);GO:0046872(metal ion binding);GO:0048208(COPII vesicle coating)","NA","K20364","NA","multiple coagulation factor deficiency 2 [Source:HGNC Symbol;Acc:HGNC:18451]",{"v":8.35792,"d":"8.36"},0,{"v":0.480685,"d":"0.48"},{"v":0.006317,"d":"0.01"},0,0,{"v":1399.17761595694,"d":"1399.18"},{"v":10.4503633989841,"d":"10.45"},{"v":0.000169030144404548,"d":"0.00"},{"v":0.0159926361594512,"d":"0.02"},"up","yes"]
[90906,0,"chr17","+",77376083,77500594,"ENST00000427674",11,3937,"ENSG00000184640","SEPT9","GO:0000166(nucleotide binding);GO:0001725(stress fiber);GO:0003924(GTPase activity);GO:0005515(protein binding);GO:0005525(GTP binding);GO:0005737(cytoplasm);GO:0005856(cytoskeleton);GO:0005874(microtubule);GO:0005930(axoneme);GO:0005940(septin ring);GO:0007049(cell cycle);GO:0015629(actin cytoskeleton);GO:0015630(microtubule cytoskeleton);GO:0031105(septin complex);GO:0032947(protein-containing complex scaffold activity);GO:0045296(cadherin binding);GO:0048471(perinuclear region of cytoplasm);GO:0051291(protein heterooligomerization);GO:0051301(cell division);GO:0061640(cytoskeleton-dependent cytokinesis);GO:0097730(non-motile cilium);GO:1902857(positive regulation of non-motile cilium assembly)","05100(Bacterial invasion of epithelial cells)","K16938","NA","septin 9 [Source:HGNC Symbol;Acc:HGNC:7323]",{"v":0.311638,"d":"0.31"},{"v":0.30512,"d":"0.31"},{"v":0.043127,"d":"0.04"},{"v":0.317579,"d":"0.32"},{"v":66.914268,"d":"66.91"},{"v":0.252478,"d":"0.25"},{"v":0.00977834482303854,"d":"0.01"},{"v":-6.6761940032968,"d":"-6.68"},{"v":0.000169038598547462,"d":"0.00"},{"v":0.0159926361594512,"d":"0.02"},"down","yes"]
[54582,0,"chr14","+",22836560,22841684,"ENST00000547074",2,560,"ENSG00000157227","MMP14","GO:0001501(skeletal system development);GO:0001503(ossification);GO:0001525(angiogenesis);GO:0001541(ovarian follicle development);GO:0001666(response to hypoxia);GO:0001935(endothelial cell proliferation);GO:0001958(endochondral ossification);GO:0004175(endopeptidase activity);GO:0004222(metalloendopeptidase activity);GO:0005178(integrin binding);GO:0005515(protein binding);GO:0005615(extracellular space);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005796(Golgi lumen);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0005887(integral component of plasma membrane);GO:0005925(focal adhesion);GO:0006508(proteolysis);GO:0006979(response to oxidative stress);GO:0008233(peptidase activity);GO:0008237(metallopeptidase activity);GO:0008270(zinc ion binding);GO:0008584(male gonad development);GO:0009612(response to mechanical stimulus);GO:0009725(response to hormone);GO:0010831(positive regulation of myotube differentiation);GO:0010954(positive regulation of protein processing);GO:0014070(response to organic cyclic compound);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016477(cell migration);GO:0016485(protein processing);GO:0016787(hydrolase activity);GO:0022617(extracellular matrix disassembly);GO:0030198(extracellular matrix organization);GO:0030307(positive regulation of cell growth);GO:0030324(lung development);GO:0030335(positive regulation of cell migration);GO:0030574(collagen catabolic process);GO:0031012(extracellular matrix);GO:0031410(cytoplasmic vesicle);GO:0031638(zymogen activation);GO:0035987(endodermal cell differentiation);GO:0035988(chondrocyte proliferation);GO:0042470(melanosome);GO:0043615(astrocyte cell migration);GO:0043627(response to estrogen);GO:0044354(macropinosome);GO:0045111(intermediate filament cytoskeleton);GO:0045579(positive regulation of B cell differentiation);GO:0045746(negative regulation of Notch signaling pathway);GO:0046872(metal ion binding);GO:0048701(embryonic cranial skeleton morphogenesis);GO:0048754(branching morphogenesis of an epithelial tube);GO:0048771(tissue remodeling);GO:0048870(cell motility);GO:0051895(negative regulation of focal adhesion assembly);GO:0060322(head development);GO:0060348(bone development);GO:0070006(metalloaminopeptidase activity);GO:0097094(craniofacial suture morphogenesis);GO:1903076(regulation of protein localization to plasma membrane);GO:1905523(positive regulation of macrophage migration);GO:1990834(response to odorant)","04668(TNF signaling pathway);04912(GnRH signaling pathway);04928(Parathyroid hormone synthesis, secretion and action)","K07763","EC:3.4.24.80","matrix metallopeptidase 14 [Source:HGNC Symbol;Acc:HGNC:7160]",{"v":2.064246,"d":"2.06"},{"v":57.959499,"d":"57.96"},{"v":57.661366,"d":"57.66"},{"v":1.697478,"d":"1.70"},{"v":1.745639,"d":"1.75"},{"v":1.629567,"d":"1.63"},{"v":23.1997717579096,"d":"23.20"},{"v":4.53603870690609,"d":"4.54"},{"v":0.000172869520571139,"d":"0.00"},{"v":0.0162842441371707,"d":"0.02"},"up","yes"]
[2698,0,"chr1","-",23428563,23436677,"ENST00000495646",10,2552,"ENSG00000088280","ASAP3","GO:0001726(ruffle);GO:0005096(GTPase activator activity);GO:0005515(protein binding);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005925(focal adhesion);GO:0016477(cell migration);GO:0043231(intracellular membrane-bounded organelle);GO:0043547(positive regulation of GTPase activity);GO:0046872(metal ion binding);GO:0051492(regulation of stress fiber assembly)","04144(Endocytosis);04666(Fc gamma R-mediated phagocytosis)","K12488","NA","ArfGAP with SH3 domain, ankyrin repeat and PH domain 3 [Source:HGNC Symbol;Acc:HGNC:14987]",{"v":2.454199,"d":"2.45"},{"v":12.504177,"d":"12.50"},{"v":0.07998,"d":"0.08"},{"v":0.095354,"d":"0.10"},{"v":0.054804,"d":"0.05"},{"v":0.108789,"d":"0.11"},{"v":58.0750346596022,"d":"58.08"},{"v":5.85984620493257,"d":"5.86"},{"v":0.000173594456644311,"d":"0.00"},{"v":0.0162842441371707,"d":"0.02"},"up","yes"]
[199768,0,"chr9","+",129111314,129148945,"ENST00000337738",11,2845,"ENSG00000119383","PTPA","GO:0000159(protein phosphatase type 2A complex);GO:0000166(nucleotide binding);GO:0000413(protein peptidyl-prolyl isomerization);GO:0003755(peptidyl-prolyl cis-trans isomerase activity);GO:0005102(signaling receptor binding);GO:0005515(protein binding);GO:0005524(ATP binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0007052(mitotic spindle organization);GO:0008160(protein tyrosine phosphatase activator activity);GO:0016853(isomerase activity);GO:0016887(ATPase activity);GO:0019211(phosphatase activator activity);GO:0019888(protein phosphatase regulator activity);GO:0032515(negative regulation of phosphoprotein phosphatase activity);GO:0032516(positive regulation of phosphoprotein phosphatase activity);GO:0034704(calcium channel complex);GO:0035307(positive regulation of protein dephosphorylation);GO:0035308(negative regulation of protein dephosphorylation);GO:0042803(protein homodimerization activity);GO:0043065(positive regulation of apoptotic process);GO:0043085(positive regulation of catalytic activity);GO:0043666(regulation of phosphoprotein phosphatase activity);GO:0046982(protein heterodimerization activity);GO:0051721(protein phosphatase 2A binding);GO:0070062(extracellular exosome)","04931(Insulin resistance)","NA","NA","protein phosphatase 2 phosphatase activator [Source:HGNC Symbol;Acc:HGNC:9308]",{"v":14.042591,"d":"14.04"},{"v":0.747249,"d":"0.75"},{"v":31.360922,"d":"31.36"},{"v":0.722368,"d":"0.72"},{"v":0.959775,"d":"0.96"},{"v":0.842215,"d":"0.84"},{"v":18.2821778844364,"d":"18.28"},{"v":4.19236603814549,"d":"4.19"},{"v":0.000173649125942084,"d":"0.00"},{"v":0.0162842441371707,"d":"0.02"},"up","yes"]
[51073,0,"chr13","-",36303602,36346493,"ENST00000494062",10,3018,"ENSG00000133104","SPART","GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0005741(mitochondrial outer membrane);GO:0005811(lipid droplet);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0009838(abscission);GO:0030496(midbody);GO:0030514(negative regulation of BMP signaling pathway);GO:0031625(ubiquitin protein ligase binding);GO:0034389(lipid droplet organization);GO:0045202(synapse);GO:0048698(negative regulation of collateral sprouting in absence of injury);GO:0050905(neuromuscular process);GO:0051301(cell division);GO:0051881(regulation of mitochondrial membrane potential);GO:0060612(adipose tissue development)","04144(Endocytosis)","K19366","NA","spartin [Source:HGNC Symbol;Acc:HGNC:18514]",{"v":18.213224,"d":"18.21"},{"v":13.87422,"d":"13.87"},{"v":0.2246,"d":"0.22"},{"v":0.601934,"d":"0.60"},{"v":0.233212,"d":"0.23"},{"v":0.304594,"d":"0.30"},{"v":28.3503641181322,"d":"28.35"},{"v":4.82529535943935,"d":"4.83"},{"v":0.000173913755167141,"d":"0.00"},{"v":0.0162842441371707,"d":"0.02"},"up","yes"]
[25303,0,"chr10","+",130136399,130184521,"ENST00000481034",13,1921,"ENSG00000108010","GLRX3","GO:0002026(regulation of the force of heart contraction);GO:0003723(RNA binding);GO:0005080(protein kinase C binding);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005938(cell cortex);GO:0006879(cellular iron ion homeostasis);GO:0009055(electron transfer activity);GO:0010614(negative regulation of cardiac muscle hypertrophy);GO:0015035(protein disulfide oxidoreductase activity);GO:0015038(glutathione disulfide oxidoreductase activity);GO:0022900(electron transport chain);GO:0030018(Z disc);GO:0030425(dendrite);GO:0042802(identical protein binding);GO:0044571([2Fe-2S] cluster assembly);GO:0045454(cell redox homeostasis);GO:0046872(metal ion binding);GO:0051536(iron-sulfur cluster binding);GO:0055114(oxidation-reduction process);GO:0097428(protein maturation by iron-sulfur cluster transfer)","NA","NA","NA","glutaredoxin 3 [Source:HGNC Symbol;Acc:HGNC:15987]",{"v":4.24485,"d":"4.24"},{"v":4.389415,"d":"4.39"},{"v":0.043446,"d":"0.04"},{"v":0.054722,"d":"0.05"},{"v":0.040508,"d":"0.04"},{"v":0.034624,"d":"0.03"},{"v":66.8266745729819,"d":"66.83"},{"v":6.06235217951235,"d":"6.06"},{"v":0.000175513001173841,"d":"0.00"},{"v":0.0163917412150273,"d":"0.02"},"up","yes"]
[147266,0,"chr3","+",184155311,184173614,"ENST00000649964",15,5335,"ENSG00000161202","DVL3","GO:0000790(nuclear chromatin);GO:0001934(positive regulation of protein phosphorylation);GO:0002020(protease binding);GO:0005102(signaling receptor binding);GO:0005109(frizzled binding);GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0007275(multicellular organism development);GO:0008013(beta-catenin binding);GO:0016055(Wnt signaling pathway);GO:0035556(intracellular signal transduction);GO:0035567(non-canonical Wnt signaling pathway);GO:0038031(non-canonical Wnt signaling pathway via JNK cascade);GO:0042493(response to drug);GO:0043507(positive regulation of JUN kinase activity);GO:0043547(positive regulation of GTPase activity);GO:0045893(positive regulation of transcription, DNA-templated);GO:0046982(protein heterodimerization activity);GO:0048365(Rac GTPase binding);GO:0050821(protein stabilization);GO:0060070(canonical Wnt signaling pathway);GO:0060071(Wnt signaling pathway, planar cell polarity pathway);GO:0090090(negative regulation of canonical Wnt signaling pathway);GO:0090179(planar cell polarity pathway involved in neural tube closure);GO:0150012(positive regulation of neuron projection arborization);GO:1903827(regulation of cellular protein localization);GO:1904886(beta-catenin destruction complex disassembly)","04150(mTOR signaling pathway);04310(Wnt signaling pathway);04330(Notch signaling pathway);04390(Hippo signaling pathway);04550(Signaling pathways regulating pluripotency of stem cells);04916(Melanogenesis);04934(Cushing syndrome);05165(Human papillomavirus infection);05200(Pathways in cancer);05217(Basal cell carcinoma);05224(Breast cancer);05225(Hepatocellular carcinoma);05226(Gastric cancer)","K02353","NA","dishevelled segment polarity protein 3 [Source:HGNC Symbol;Acc:HGNC:3087]",{"v":12.844567,"d":"12.84"},{"v":0.216366,"d":"0.22"},{"v":0.035985,"d":"0.04"},{"v":0.043776,"d":"0.04"},{"v":0.044448,"d":"0.04"},{"v":0.051648,"d":"0.05"},{"v":93.6350234500114,"d":"93.64"},{"v":6.5489763544678,"d":"6.55"},{"v":0.000178502531149474,"d":"0.00"},{"v":0.0166281973247702,"d":"0.02"},"up","yes"]
[132002,0,"chr22","+",20131948,20148006,"ENST00000405930",11,3112,"ENSG00000099904","ZDHHC8","GO:0005739(mitochondrion);GO:0005794(Golgi apparatus);GO:0005829(cytosol);GO:0007626(locomotory behavior);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016409(palmitoyltransferase activity);GO:0016740(transferase activity);GO:0016746(transferase activity, transferring acyl groups);GO:0018345(protein palmitoylation);GO:0019706(protein-cysteine S-palmitoyltransferase activity);GO:0030659(cytoplasmic vesicle membrane);GO:0031410(cytoplasmic vesicle);GO:0034380(high-density lipoprotein particle assembly)","NA","K20030","EC:2.3.1.225","zinc finger DHHC-type containing 8 [Source:HGNC Symbol;Acc:HGNC:18474]",0,0,0,{"v":1.010479,"d":"1.01"},{"v":0.794322,"d":"0.79"},0,"-inf","-inf",{"v":0.000188493347516583,"d":"0.00"},{"v":0.0175139726733439,"d":"0.02"},"down","yes"]
[35527,0,"chr11","-",95832882,95924295,"ENST00000346299",15,4681,"ENSG00000087053","MTMR2","GO:0002091(negative regulation of receptor internalization);GO:0004438(phosphatidylinositol-3-phosphatase activity);GO:0004725(protein tyrosine phosphatase activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005768(endosome);GO:0005774(vacuolar membrane);GO:0005829(cytosol);GO:0006470(protein dephosphorylation);GO:0006629(lipid metabolic process);GO:0006661(phosphatidylinositol biosynthetic process);GO:0008021(synaptic vesicle);GO:0008138(protein tyrosine/serine/threonine phosphatase activity);GO:0010008(endosome membrane);GO:0014069(postsynaptic density);GO:0016020(membrane);GO:0016311(dephosphorylation);GO:0016787(hydrolase activity);GO:0016791(phosphatase activity);GO:0030424(axon);GO:0030425(dendrite);GO:0031642(negative regulation of myelination);GO:0031901(early endosome membrane);GO:0032288(myelin assembly);GO:0035335(peptidyl-tyrosine dephosphorylation);GO:0042803(protein homodimerization activity);GO:0042995(cell projection);GO:0043197(dendritic spine);GO:0043231(intracellular membrane-bounded organelle);GO:0045806(negative regulation of endocytosis);GO:0046488(phosphatidylinositol metabolic process);GO:0046855(inositol phosphate dephosphorylation);GO:0046856(phosphatidylinositol dephosphorylation);GO:0048471(perinuclear region of cytoplasm);GO:0048666(neuron development);GO:0052629(phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity);GO:0052866(phosphatidylinositol phosphate phosphatase activity);GO:0060304(regulation of phosphatidylinositol dephosphorylation);GO:0070062(extracellular exosome);GO:0090394(negative regulation of excitatory postsynaptic potential);GO:0097060(synaptic membrane);GO:0097062(dendritic spine maintenance);GO:2000643(positive regulation of early endosome to late endosome transport);GO:2000645(negative regulation of receptor catabolic process)","00562(Inositol phosphate metabolism);04070(Phosphatidylinositol signaling system)","K18081","3.1.3.95;EC:3.1.3.64","myotubularin related protein 2 [Source:HGNC Symbol;Acc:HGNC:7450]",{"v":2.503449,"d":"2.50"},{"v":0.013164,"d":"0.01"},{"v":0.980229,"d":"0.98"},{"v":0.015525,"d":"0.02"},{"v":0.018839,"d":"0.02"},{"v":0.011174,"d":"0.01"},{"v":76.7895384074838,"d":"76.79"},{"v":6.26283787047308,"d":"6.26"},{"v":0.000191594768705592,"d":"0.00"},{"v":0.0177567294568218,"d":"0.02"},"up","yes"]
[181249,0,"chr7","-",94585224,94656218,"ENST00000265735",11,1709,"ENSG00000127990","SGCE","GO:0005509(calcium ion binding);GO:0005737(cytoplasm);GO:0005794(Golgi apparatus);GO:0005856(cytoskeleton);GO:0005886(plasma membrane);GO:0005887(integral component of plasma membrane);GO:0007160(cell-matrix adhesion);GO:0007517(muscle organ development);GO:0016010(dystrophin-associated glycoprotein complex);GO:0016012(sarcoglycan complex);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0030425(dendrite);GO:0032590(dendrite membrane);GO:0042383(sarcolemma);GO:0042995(cell projection)","NA","NA","NA","sarcoglycan epsilon [Source:HGNC Symbol;Acc:HGNC:10808]",{"v":0.815782,"d":"0.82"},{"v":1.488671,"d":"1.49"},{"v":2.016537,"d":"2.02"},{"v":13.057041,"d":"13.06"},{"v":5.538967,"d":"5.54"},{"v":32.485828,"d":"32.49"},{"v":0.0845895593885858,"d":"0.08"},{"v":-3.56337658255051,"d":"-3.56"},{"v":0.000202963187010137,"d":"0.00"},{"v":0.0187464873804017,"d":"0.02"},"down","yes"]
[199168,0,"chr9","+",127210745,127223166,"ENST00000438723",6,4858,"ENSG00000136828","RALGPS1","GO:0005085(guanyl-nucleotide exchange factor activity);GO:0005575(cellular_component);GO:0005622(intracellular);GO:0005737(cytoplasm);GO:0005886(plasma membrane);GO:0007264(small GTPase mediated signal transduction);GO:0008321(Ral guanyl-nucleotide exchange factor activity);GO:0016020(membrane);GO:0032485(regulation of Ral protein signal transduction);GO:0035556(intracellular signal transduction)","NA","NA","NA","Ral GEF with PH domain and SH3 binding motif 1 [Source:HGNC Symbol;Acc:HGNC:16851]",0,0,0,{"v":0.579069,"d":"0.58"},{"v":0.54358,"d":"0.54"},0,"-inf","-inf",{"v":0.000203306249047021,"d":"0.00"},{"v":0.0187464873804017,"d":"0.02"},"down","yes"]
[203518,0,"chrX","-",53532096,53654107,"ENST00000612484",81,14311,"ENSG00000086758","HUWE1","GO:0000209(protein polyubiquitination);GO:0003677(DNA binding);GO:0003723(RNA binding);GO:0004842(ubiquitin-protein transferase activity);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0006281(DNA repair);GO:0006284(base-excision repair);GO:0006511(ubiquitin-dependent protein catabolic process);GO:0006513(protein monoubiquitination);GO:0006974(cellular response to DNA damage stimulus);GO:0016020(membrane);GO:0016567(protein ubiquitination);GO:0016574(histone ubiquitination);GO:0016740(transferase activity);GO:0030154(cell differentiation);GO:0031398(positive regulation of protein ubiquitination);GO:0032922(circadian regulation of gene expression);GO:0034774(secretory granule lumen);GO:0043312(neutrophil degranulation);GO:0061630(ubiquitin protein ligase activity);GO:0070062(extracellular exosome);GO:1903955(positive regulation of protein targeting to mitochondrion);GO:1904813(ficolin-1-rich granule lumen)","04120(Ubiquitin mediated proteolysis)","K10592","EC:2.3.2.26","HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase [Source:HGNC Symbol;Acc:HGNC:30892]",0,0,0,{"v":0.165347,"d":"0.17"},0,{"v":0.183378,"d":"0.18"},"-inf","-inf",{"v":0.000216298933253581,"d":"0.00"},{"v":0.0198940259369686,"d":"0.02"},"down","yes"]
[176193,0,"chr7","-",1815794,2233243,"ENST00000406869",19,2991,"ENSG00000002822","MAD1L1","GO:0000775(chromosome, centromeric region);GO:0000776(kinetochore);GO:0000777(condensed chromosome kinetochore);GO:0000922(spindle pole);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005635(nuclear envelope);GO:0005694(chromosome);GO:0005737(cytoplasm);GO:0005813(centrosome);GO:0005815(microtubule organizing center);GO:0005819(spindle);GO:0005829(cytosol);GO:0005856(cytoskeleton);GO:0007049(cell cycle);GO:0007093(mitotic cell cycle checkpoint);GO:0007094(mitotic spindle assembly checkpoint);GO:0042130(negative regulation of T cell proliferation);GO:0042802(identical protein binding);GO:0043515(kinetochore binding);GO:0044615(nuclear pore nuclear basket);GO:0048538(thymus development);GO:0051301(cell division);GO:0051315(attachment of mitotic spindle microtubules to kinetochore);GO:0072686(mitotic spindle);GO:0090235(regulation of metaphase plate congression);GO:0097431(mitotic spindle pole);GO:1901990(regulation of mitotic cell cycle phase transition)","04110(Cell cycle);04114(Oocyte meiosis);04914(Progesterone-mediated oocyte maturation);05166(Human T-cell leukemia virus 1 infection);05203(Viral carcinogenesis)","NA","NA","mitotic arrest deficient 1 like 1 [Source:HGNC Symbol;Acc:HGNC:6762]",{"v":1.181565,"d":"1.18"},{"v":1.274439,"d":"1.27"},{"v":0.140072,"d":"0.14"},0,0,{"v":0.028021,"d":"0.03"},{"v":92.6475143642268,"d":"92.65"},{"v":6.53368036566222,"d":"6.53"},{"v":0.000219480348976521,"d":"0.00"},{"v":0.0201356592886793,"d":"0.02"},"up","yes"]
[73153,0,"chr16","-",28537537,28539008,"ENST00000395641",3,550,"ENSG00000176046","NUPR1","GO:0002526(acute inflammatory response);GO:0003677(DNA binding);GO:0003682(chromatin binding);GO:0003713(transcription coactivator activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0006473(protein acetylation);GO:0008283(cell population proliferation);GO:0008285(negative regulation of cell population proliferation);GO:0008584(male gonad development);GO:0009636(response to toxic substance);GO:0010506(regulation of autophagy);GO:0010507(negative regulation of autophagy);GO:0010667(negative regulation of cardiac muscle cell apoptotic process);GO:0010698(acetyltransferase activator activity);GO:0031401(positive regulation of protein modification process);GO:0032993(protein-DNA complex);GO:0035914(skeletal muscle cell differentiation);GO:0042771(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator);GO:0043065(positive regulation of apoptotic process);GO:0043066(negative regulation of apoptotic process);GO:0043085(positive regulation of catalytic activity);GO:0043433(negative regulation of DNA-binding transcription factor activity);GO:0043525(positive regulation of neuron apoptotic process);GO:0045786(negative regulation of cell cycle);GO:0045820(negative regulation of glycolytic process);GO:0048147(negative regulation of fibroblast proliferation);GO:0048471(perinuclear region of cytoplasm);GO:0050680(negative regulation of epithelial cell proliferation);GO:0062099(negative regulation of programmed necrotic cell death);GO:0065003(protein-containing complex assembly);GO:0150078(positive regulation of neuroinflammatory response);GO:1901800(positive regulation of proteasomal protein catabolic process);GO:1902902(negative regulation of autophagosome assembly);GO:1903508(positive regulation of nucleic acid-templated transcription);GO:1903862(positive regulation of oxidative phosphorylation);GO:1904036(negative regulation of epithelial cell apoptotic process);GO:1904691(negative regulation of type B pancreatic cell proliferation);GO:1905897(regulation of response to endoplasmic reticulum stress);GO:2000194(regulation of female gonad development);GO:2001244(positive regulation of intrinsic apoptotic signaling pathway)","05202(Transcriptional misregulation in cancer)","K15626","NA","nuclear protein 1, transcriptional regulator [Source:HGNC Symbol;Acc:HGNC:29990]",{"v":100.21402,"d":"100.21"},{"v":102.306648,"d":"102.31"},{"v":97.596947,"d":"97.60"},{"v":17.148251,"d":"17.15"},{"v":14.610444,"d":"14.61"},{"v":14.533354,"d":"14.53"},{"v":6.48313525720151,"d":"6.48"},{"v":2.6966916720792,"d":"2.70"},{"v":0.000221639850890403,"d":"0.00"},{"v":0.0202825586469731,"d":"0.02"},"up","yes"]
[18906,0,"chr10","+",6202866,6228284,"ENST00000317350",15,1999,"ENSG00000170525","PFKFB3","GO:0000166(nucleotide binding);GO:0003824(catalytic activity);GO:0003873(6-phosphofructo-2-kinase activity);GO:0004331(fructose-2,6-bisphosphate 2-phosphatase activity);GO:0005524(ATP binding);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0006000(fructose metabolic process);GO:0006003(fructose 2,6-bisphosphate metabolic process);GO:0007420(brain development);GO:0008152(metabolic process);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0016311(dephosphorylation);GO:0016740(transferase activity);GO:0016787(hydrolase activity);GO:0045821(positive regulation of glycolytic process);GO:0046835(carbohydrate phosphorylation)","00051(Fructose and mannose metabolism);04066(HIF-1 signaling pathway);04152(AMPK signaling pathway)","K01103","3.1.3.46;EC:2.7.1.105","6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 [Source:HGNC Symbol;Acc:HGNC:8874]",{"v":1.686332,"d":"1.69"},0,{"v":0.995612,"d":"1.00"},0,0,0,"inf","inf",{"v":0.00022330846325661,"d":"0.00"},{"v":0.0203839107289262,"d":"0.02"},"up","yes"]
[166044,0,"chr5","+",177600162,177609707,"ENST00000505433",6,1064,"ENSG00000027847","B4GALT7","GO:0000139(Golgi membrane);GO:0003831(beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity);GO:0005515(protein binding);GO:0005794(Golgi apparatus);GO:0005975(carbohydrate metabolic process);GO:0006024(glycosaminoglycan biosynthetic process);GO:0006029(proteoglycan metabolic process);GO:0006464(cellular protein modification process);GO:0006486(protein glycosylation);GO:0006487(protein N-linked glycosylation);GO:0008378(galactosyltransferase activity);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016740(transferase activity);GO:0016757(transferase activity, transferring glycosyl groups);GO:0030145(manganese ion binding);GO:0030203(glycosaminoglycan metabolic process);GO:0032580(Golgi cisterna membrane);GO:0046525(xylosylprotein 4-beta-galactosyltransferase activity);GO:0046872(metal ion binding);GO:0048147(negative regulation of fibroblast proliferation);GO:0097435(supramolecular fiber organization)","00532(Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate);00534(Glycosaminoglycan biosynthesis - heparan sulfate / heparin)","NA","NA","beta-1,4-galactosyltransferase 7 [Source:HGNC Symbol;Acc:HGNC:930]",{"v":3.691608,"d":"3.69"},{"v":1.537692,"d":"1.54"},0,0,0,0,"inf","inf",{"v":0.00022469100532693,"d":"0.00"},{"v":0.0204587073271363,"d":"0.02"},"up","yes"]
[179993,0,"chr7","+",74028157,74069678,"ENST00000380575",30,3043,"ENSG00000049540","ELN","GO:0003151(outflow tract morphogenesis);GO:0003180(aortic valve morphogenesis);GO:0005201(extracellular matrix structural constituent);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0007519(skeletal muscle tissue development);GO:0007585(respiratory gaseous exchange);GO:0008015(blood circulation);GO:0008283(cell population proliferation);GO:0009887(animal organ morphogenesis);GO:0030023(extracellular matrix constituent conferring elasticity);GO:0030198(extracellular matrix organization);GO:0030833(regulation of actin filament polymerization);GO:0031012(extracellular matrix);GO:0043149(stress fiber assembly);GO:0050840(extracellular matrix binding);GO:0062023(collagen-containing extracellular matrix);GO:0071953(elastic fiber)","04974(Protein digestion and absorption)","K14211","NA","elastin [Source:HGNC Symbol;Acc:HGNC:3327]",0,0,0,{"v":0.56534,"d":"0.57"},0,{"v":1.090536,"d":"1.09"},"-inf","-inf",{"v":0.000225867822856201,"d":"0.00"},{"v":0.0205144450109144,"d":"0.02"},"down","yes"]
[181491,0,"chr7","+",97117723,97181487,"ENST00000360382",3,731,"ENSG00000196636","SDHAF3","GO:0005739(mitochondrion);GO:0005758(mitochondrial intermembrane space);GO:0005759(mitochondrial matrix);GO:0006105(succinate metabolic process);GO:0006111(regulation of gluconeogenesis);GO:0034553(mitochondrial respiratory chain complex II assembly)","NA","NA","NA","succinate dehydrogenase complex assembly factor 3 [Source:HGNC Symbol;Acc:HGNC:21752]",{"v":1.56946,"d":"1.57"},{"v":2.392342,"d":"2.39"},{"v":2.38542,"d":"2.39"},{"v":0.071823,"d":"0.07"},0,{"v":0.017322,"d":"0.02"},{"v":71.2010993325481,"d":"71.20"},{"v":6.15382761121066,"d":"6.15"},{"v":0.00022933167467543,"d":"0.00"},{"v":0.0207771065859311,"d":"0.02"},"up","yes"]
[91830,0,"chr17","-",81904424,81911267,"ENST00000570391",13,1857,"ENSG00000185813","PCYT2","GO:0003824(catalytic activity);GO:0004306(ethanolamine-phosphate cytidylyltransferase activity);GO:0005575(cellular_component);GO:0005789(endoplasmic reticulum membrane);GO:0006629(lipid metabolic process);GO:0006646(phosphatidylethanolamine biosynthetic process);GO:0008654(phospholipid biosynthetic process);GO:0009058(biosynthetic process);GO:0016740(transferase activity);GO:0016779(nucleotidyltransferase activity)","00440(Phosphonate and phosphinate metabolism);00564(Glycerophospholipid metabolism)","K00967","EC:2.7.7.14","phosphate cytidylyltransferase 2, ethanolamine [Source:HGNC Symbol;Acc:HGNC:8756]",0,0,0,{"v":1.244469,"d":"1.24"},{"v":1.516733,"d":"1.52"},0,"-inf","-inf",{"v":0.000230677318686162,"d":"0.00"},{"v":0.02084703230813,"d":"0.02"},"down","yes"]
[205613,0,"chrX","+",115593553,115650056,"ENST00000481823",17,2858,"ENSG00000102024","PLS3","GO:0003779(actin binding);GO:0005509(calcium ion binding);GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005884(actin filament);GO:0005886(plasma membrane);GO:0032432(actin filament bundle);GO:0046872(metal ion binding);GO:0051015(actin filament binding);GO:0051017(actin filament bundle assembly);GO:0051639(actin filament network formation);GO:0060348(bone development)","NA","K17336","NA","plastin 3 [Source:HGNC Symbol;Acc:HGNC:9091]",{"v":66.536598,"d":"66.54"},{"v":0.847774,"d":"0.85"},{"v":0.007692,"d":"0.01"},{"v":0.004174,"d":"0.00"},{"v":0.079103,"d":"0.08"},{"v":0.209817,"d":"0.21"},{"v":229.933277378588,"d":"229.93"},{"v":7.84507146676952,"d":"7.85"},{"v":0.000232044413931316,"d":"0.00"},{"v":0.0209185448092425,"d":"0.02"},"up","yes"]
[92695,0,"chr18","-",5392381,5540556,"ENST00000544123",21,3972,"ENSG00000082397","EPB41L3","GO:0001558(regulation of cell growth);GO:0002175(protein localization to paranode region of axon);GO:0003779(actin binding);GO:0005198(structural molecule activity);GO:0005200(structural constituent of cytoskeleton);GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005856(cytoskeleton);GO:0005886(plasma membrane);GO:0005911(cell-cell junction);GO:0006915(apoptotic process);GO:0007010(cytoskeleton organization);GO:0007016(cytoskeletal anchoring at plasma membrane);GO:0008092(cytoskeletal protein binding);GO:0008150(biological_process);GO:0008360(regulation of cell shape);GO:0014069(postsynaptic density);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0030054(cell junction);GO:0030673(axolemma);GO:0030865(cortical cytoskeleton organization);GO:0030866(cortical actin cytoskeleton organization);GO:0030913(paranodal junction assembly);GO:0031032(actomyosin structure organization);GO:0033270(paranode region of axon);GO:0043217(myelin maintenance);GO:0044224(juxtaparanode region of axon);GO:0048812(neuron projection morphogenesis);GO:0071205(protein localization to juxtaparanode region of axon);GO:0072659(protein localization to plasma membrane)","NA","K06107","NA","erythrocyte membrane protein band 4.1 like 3 [Source:HGNC Symbol;Acc:HGNC:3380]",0,0,0,{"v":0.631559,"d":"0.63"},0,{"v":0.584463,"d":"0.58"},"-inf","-inf",{"v":0.000236699284162133,"d":"0.00"},{"v":0.0212581472059749,"d":"0.02"},"down","yes"]
[35375,0,"chr11","+",93784307,93812378,"ENST00000639724",11,2317,"ENSG00000042429","MED17","GO:0000151(ubiquitin ligase complex);GO:0003712(transcription coregulator activity);GO:0003713(transcription coactivator activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005667(transcription factor complex);GO:0006357(regulation of transcription by RNA polymerase II);GO:0006367(transcription initiation from RNA polymerase II promoter);GO:0016020(membrane);GO:0016567(protein ubiquitination);GO:0016592(mediator complex);GO:0019827(stem cell population maintenance);GO:0030374(nuclear receptor transcription coactivator activity);GO:0042809(vitamin D receptor binding);GO:0045893(positive regulation of transcription, DNA-templated);GO:0045944(positive regulation of transcription by RNA polymerase II);GO:0046966(thyroid hormone receptor binding);GO:0061630(ubiquitin protein ligase activity);GO:0070847(core mediator complex)","04919(Thyroid hormone signaling pathway)","K15133","NA","mediator complex subunit 17 [Source:HGNC Symbol;Acc:HGNC:2375]",0,{"v":1.445454,"d":"1.45"},{"v":0.841407,"d":"0.84"},0,0,0,"inf","inf",{"v":0.000236981822692536,"d":"0.00"},{"v":0.0212581472059749,"d":"0.02"},"up","yes"]
[21895,0,"chr10","+",72692619,72887692,"ENST00000605597",8,3224,"ENSG00000156026","MCU","GO:0005262(calcium channel activity);GO:0005515(protein binding);GO:0005739(mitochondrion);GO:0005743(mitochondrial inner membrane);GO:0006811(ion transport);GO:0006816(calcium ion transport);GO:0006851(mitochondrial calcium ion transmembrane transport);GO:0015292(uniporter activity);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0019722(calcium-mediated signaling);GO:0031305(integral component of mitochondrial inner membrane);GO:0032024(positive regulation of insulin secretion);GO:0034704(calcium channel complex);GO:0036444(calcium import into the mitochondrion);GO:0042593(glucose homeostasis);GO:0042802(identical protein binding);GO:0051259(protein complex oligomerization);GO:0051560(mitochondrial calcium ion homeostasis);GO:0051561(positive regulation of mitochondrial calcium ion concentration);GO:0070588(calcium ion transmembrane transport);GO:1990246(uniplex complex)","04020(Calcium signaling pathway);04218(Cellular senescence);04621(NOD-like receptor signaling pathway)","K20858","NA","mitochondrial calcium uniporter [Source:HGNC Symbol;Acc:HGNC:23526]",{"v":1.538793,"d":"1.54"},{"v":0.030411,"d":"0.03"},{"v":1.829603,"d":"1.83"},{"v":0.011286,"d":"0.01"},{"v":0.024136,"d":"0.02"},{"v":0.028298,"d":"0.03"},{"v":53.3397206528563,"d":"53.34"},{"v":5.737138364212,"d":"5.74"},{"v":0.000237570979746962,"d":"0.00"},{"v":0.0212585066359782,"d":"0.02"},"up","yes"]
[167106,0,"chr6","-",7296883,7313188,"ENST00000462112",7,1094,"ENSG00000124783","SSR1","GO:0005515(protein binding);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0006613(cotranslational protein targeting to membrane);GO:0008284(positive regulation of cell population proliferation);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0036498(IRE1-mediated unfolded protein response)","04141(Protein processing in endoplasmic reticulum)","K13249","NA","signal sequence receptor subunit 1 [Source:HGNC Symbol;Acc:HGNC:11323]",{"v":5.520757,"d":"5.52"},0,{"v":10.383158,"d":"10.38"},{"v":0.027442,"d":"0.03"},0,0,{"v":579.546498068654,"d":"579.55"},{"v":9.17878060569484,"d":"9.18"},{"v":0.000239691396112134,"d":"0.00"},{"v":0.0213955489453411,"d":"0.02"},"up","yes"]
[109955,0,"chr2","-",11181652,11344585,"ENST00000616279",32,6401,"ENSG00000134318","ROCK2","GO:0000166(nucleotide binding);GO:0001934(positive regulation of protein phosphorylation);GO:0002931(response to ischemia);GO:0003180(aortic valve morphogenesis);GO:0003723(RNA binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005198(structural molecule activity);GO:0005515(protein binding);GO:0005524(ATP binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005813(centrosome);GO:0005815(microtubule organizing center);GO:0005829(cytosol);GO:0005856(cytoskeleton);GO:0005886(plasma membrane);GO:0006468(protein phosphorylation);GO:0006939(smooth muscle contraction);GO:0007186(G protein-coupled receptor signaling pathway);GO:0007249(I-kappaB kinase/NF-kappaB signaling);GO:0007266(Rho protein signal transduction);GO:0010595(positive regulation of endothelial cell migration);GO:0010613(positive regulation of cardiac muscle hypertrophy);GO:0010628(positive regulation of gene expression);GO:0010629(negative regulation of gene expression);GO:0010825(positive regulation of centrosome duplication);GO:0016020(membrane);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0016525(negative regulation of angiogenesis);GO:0016740(transferase activity);GO:0017048(Rho GTPase binding);GO:0017049(GTP-Rho binding);GO:0018105(peptidyl-serine phosphorylation);GO:0018107(peptidyl-threonine phosphorylation);GO:0030036(actin cytoskeleton organization);GO:0030155(regulation of cell adhesion);GO:0030335(positive regulation of cell migration);GO:0030866(cortical actin cytoskeleton organization);GO:0031644(regulation of neurological system process);GO:0032723(positive regulation of connective tissue growth factor production);GO:0032956(regulation of actin cytoskeleton organization);GO:0035509(negative regulation of myosin-light-chain-phosphatase activity);GO:0035556(intracellular signal transduction);GO:0036464(cytoplasmic ribonucleoprotein granule);GO:0039694(viral RNA genome replication);GO:0042752(regulation of circadian rhythm);GO:0043410(positive regulation of MAPK cascade);GO:0045019(negative regulation of nitric oxide biosynthetic process);GO:0045616(regulation of keratinocyte differentiation);GO:0046872(metal ion binding);GO:0048010(vascular endothelial growth factor receptor signaling pathway);GO:0048013(ephrin receptor signaling pathway);GO:0048156(tau protein binding);GO:0048511(rhythmic process);GO:0050321(tau-protein kinase activity);GO:0051246(regulation of protein metabolic process);GO:0051298(centrosome duplication);GO:0051492(regulation of stress fiber assembly);GO:0051493(regulation of cytoskeleton organization);GO:0051496(positive regulation of stress fiber assembly);GO:0051893(regulation of focal adhesion assembly);GO:0061157(mRNA destabilization);GO:0070168(negative regulation of biomineral tissue development);GO:0071394(cellular response to testosterone stimulus);GO:0071559(response to transforming growth factor beta);GO:0072518(Rho-dependent protein serine/threonine kinase activity);GO:0072659(protein localization to plasma membrane);GO:0090271(positive regulation of fibroblast growth factor production);GO:0097746(regulation of blood vessel diameter);GO:0110061(regulation of angiotensin-activated signaling pathway);GO:0150033(negative regulation of protein localization to lysosome);GO:1900037(regulation of cellular response to hypoxia);GO:1902004(positive regulation of amyloid-beta formation);GO:1902961(positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process);GO:1902966(positive regulation of protein localization to early endosome);GO:1902993(positive regulation of amyloid precursor protein catabolic process);GO:1903140(regulation of establishment of endothelial barrier);GO:1903347(negative regulation of bicellular tight junction assembly);GO:1905145(cellular response to acetylcholine);GO:1905205(positive regulation of connective tissue replacement);GO:1990776(response to angiotensin);GO:2000114(regulation of establishment of cell polarity);GO:2000145(regulation of cell motility)","04022(cGMP-PKG signaling pathway);04024(cAMP signaling pathway);04062(Chemokine signaling pathway);04071(Sphingolipid signaling pathway);04270(Vascular smooth muscle contraction);04310(Wnt signaling pathway);04360(Axon guidance);04510(Focal adhesion);04530(Tight junction);04611(Platelet activation);04670(Leukocyte transendothelial migration);04810(Regulation of actin cytoskeleton);04921(Oxytocin signaling pathway);05130(Pathogenic Escherichia coli infection);05131(Shigellosis);05132(Salmonella infection);05163(Human cytomegalovirus infection);05200(Pathways in cancer);05205(Proteoglycans in cancer)","K17388","EC:2.7.11.1","Rho associated coiled-coil containing protein kinase 2 [Source:HGNC Symbol;Acc:HGNC:10252]",{"v":0.495419,"d":"0.50"},{"v":0.12549,"d":"0.13"},{"v":0.061321,"d":"0.06"},{"v":9.543421,"d":"9.54"},{"v":10.085231,"d":"10.09"},{"v":0.131398,"d":"0.13"},{"v":0.0345257223539414,"d":"0.03"},{"v":-4.85618459062675,"d":"-4.86"},{"v":0.000255140144664221,"d":"0.00"},{"v":0.0227187290579685,"d":"0.02"},"down","yes"]
[10932,0,"chr1","+",150508094,150510552,"ENST00000496744",4,1030,"ENSG00000143369","ECM1","GO:0001503(ossification);GO:0001525(angiogenesis);GO:0001938(positive regulation of endothelial cell proliferation);GO:0001960(negative regulation of cytokine-mediated signaling pathway);GO:0002020(protease binding);GO:0002063(chondrocyte development);GO:0002576(platelet degranulation);GO:0002828(regulation of type 2 immune response);GO:0003416(endochondral bone growth);GO:0005134(interleukin-2 receptor binding);GO:0005201(extracellular matrix structural constituent);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0005615(extracellular space);GO:0006357(regulation of transcription by RNA polymerase II);GO:0006954(inflammatory response);GO:0007165(signal transduction);GO:0008022(protein C-terminus binding);GO:0010466(negative regulation of peptidase activity);GO:0019899(enzyme binding);GO:0030500(regulation of bone mineralization);GO:0030502(negative regulation of bone mineralization);GO:0031012(extracellular matrix);GO:0031089(platelet dense granule lumen);GO:0031214(biomineral tissue development);GO:0043123(positive regulation of I-kappaB kinase/NF-kappaB signaling);GO:0043236(laminin binding);GO:0045766(positive regulation of angiogenesis);GO:0062023(collagen-containing extracellular matrix);GO:0070062(extracellular exosome);GO:2000404(regulation of T cell migration)","NA","NA","NA","extracellular matrix protein 1 [Source:HGNC Symbol;Acc:HGNC:3153]",{"v":4.237871,"d":"4.24"},{"v":5.199356,"d":"5.20"},{"v":2.073968,"d":"2.07"},{"v":0.158562,"d":"0.16"},{"v":0.180143,"d":"0.18"},{"v":0.25835,"d":"0.26"},{"v":19.2799574578556,"d":"19.28"},{"v":4.26902996308343,"d":"4.27"},{"v":0.000256551316325223,"d":"0.00"},{"v":0.0227885313498664,"d":"0.02"},"up","yes"]
[37131,0,"chr11","+",119084885,119093516,"ENST00000537841",14,1559,"ENSG00000256269","HMBS","GO:0004418(hydroxymethylbilane synthase activity);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0006779(porphyrin-containing compound biosynthetic process);GO:0006782(protoporphyrinogen IX biosynthetic process);GO:0006783(heme biosynthetic process);GO:0016740(transferase activity);GO:0018160(peptidyl-pyrromethane cofactor linkage);GO:0033014(tetrapyrrole biosynthetic process)","00860(Porphyrin and chlorophyll metabolism)","K01749","EC:2.5.1.61","hydroxymethylbilane synthase [Source:HGNC Symbol;Acc:HGNC:4982]",{"v":0.097966,"d":"0.10"},{"v":0.040425,"d":"0.04"},{"v":0.082037,"d":"0.08"},{"v":0.575404,"d":"0.58"},{"v":1.572432,"d":"1.57"},{"v":2.823491,"d":"2.82"},{"v":0.0443398714266835,"d":"0.04"},{"v":-4.49525160297851,"d":"-4.50"},{"v":0.000258357019196515,"d":"0.00"},{"v":0.0228929524570961,"d":"0.02"},"down","yes"]
[58339,0,"chr14","+",73886871,73931817,"ENST00000442160",14,2076,"ENSG00000119725","ZNF410","GO:0000981(DNA-binding transcription factor activity, RNA polymerase II-specific);GO:0003676(nucleic acid binding);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0005634(nucleus);GO:0006357(regulation of transcription by RNA polymerase II);GO:0046872(metal ion binding)","NA","NA","NA","zinc finger protein 410 [Source:HGNC Symbol;Acc:HGNC:20144]",{"v":0.011385,"d":"0.01"},0,{"v":0.021948,"d":"0.02"},{"v":0.536866,"d":"0.54"},{"v":0.641856,"d":"0.64"},{"v":0.933393,"d":"0.93"},{"v":0.0157818111229739,"d":"0.02"},{"v":-5.98559341102672,"d":"-5.99"},{"v":0.000266019942428768,"d":"0.00"},{"v":0.0235146095095794,"d":"0.02"},"down","yes"]
[98798,0,"chr19","+",10543917,10553067,"ENST00000588857",10,1555,"ENSG00000130734","ATG4D","GO:0005737(cytoplasm);GO:0005739(mitochondrion);GO:0005759(mitochondrial matrix);GO:0006508(proteolysis);GO:0006914(autophagy);GO:0006915(apoptotic process);GO:0008233(peptidase activity);GO:0008234(cysteine-type peptidase activity);GO:0015031(protein transport);GO:0016787(hydrolase activity)","04136(Autophagy - other);04140(Autophagy - animal)","K08342","EC:3.4.22.-","autophagy related 4D cysteine peptidase [Source:HGNC Symbol;Acc:HGNC:20789]",0,0,0,{"v":0.730142,"d":"0.73"},{"v":2.64758,"d":"2.65"},0,"-inf","-inf",{"v":0.000272249070171062,"d":"0.00"},{"v":0.02400681727989,"d":"0.02"},"down","yes"]
[47869,0,"chr12","+",110127473,110218786,"ENST00000550156",20,2694,"ENSG00000122970","IFT81","GO:0005515(protein binding);GO:0005813(centrosome);GO:0005929(cilium);GO:0007283(spermatogenesis);GO:0008589(regulation of smoothened signaling pathway);GO:0015631(tubulin binding);GO:0030030(cell projection organization);GO:0030992(intraciliary transport particle B);GO:0031514(motile cilium);GO:0035735(intraciliary transport involved in cilium assembly);GO:0036064(ciliary basal body);GO:0042073(intraciliary transport);GO:0042995(cell projection);GO:0060271(cilium assembly);GO:0097225(sperm midpiece);GO:0097228(sperm principal piece);GO:0097542(ciliary tip)","NA","K19677","NA","intraflagellar transport 81 [Source:HGNC Symbol;Acc:HGNC:14313]",0,{"v":0.613001,"d":"0.61"},{"v":1.257263,"d":"1.26"},0,0,0,"inf","inf",{"v":0.000274411020377833,"d":"0.00"},{"v":0.0240940733615206,"d":"0.02"},"up","yes"]
[126230,0,"chr20","-",34928600,34942980,"ENST00000643502",10,1310,"ENSG00000100983","GSS","GO:0000166(nucleotide binding);GO:0000287(magnesium ion binding);GO:0004363(glutathione synthase activity);GO:0005515(protein binding);GO:0005524(ATP binding);GO:0005829(cytosol);GO:0006520(cellular amino acid metabolic process);GO:0006750(glutathione biosynthetic process);GO:0006979(response to oxidative stress);GO:0007399(nervous system development);GO:0007568(aging);GO:0009410(response to xenobiotic stimulus);GO:0016594(glycine binding);GO:0016874(ligase activity);GO:0031667(response to nutrient levels);GO:0034612(response to tumor necrosis factor);GO:0042277(peptide binding);GO:0042802(identical protein binding);GO:0042803(protein homodimerization activity);GO:0043200(response to amino acid);GO:0043295(glutathione binding);GO:0046686(response to cadmium ion);GO:0046872(metal ion binding);GO:0070062(extracellular exosome)","00270(Cysteine and methionine metabolism);00480(Glutathione metabolism);04216(Ferroptosis)","K21456","EC:6.3.2.3","glutathione synthetase [Source:HGNC Symbol;Acc:HGNC:4624]",0,{"v":2.473684,"d":"2.47"},{"v":1.346471,"d":"1.35"},0,0,0,"inf","inf",{"v":0.000274564997843918,"d":"0.00"},{"v":0.0240940733615206,"d":"0.02"},"up","yes"]
[119486,0,"chr2","-",175074474,175168169,"ENST00000428760",15,1989,"ENSG00000115966","ATF2","GO:0000122(negative regulation of transcription by RNA polymerase II);GO:0000977(RNA polymerase II regulatory region sequence-specific DNA binding);GO:0000980(RNA polymerase II distal enhancer sequence-specific DNA binding);GO:0000981(DNA-binding transcription factor activity, RNA polymerase II-specific);GO:0001102(RNA polymerase II activating transcription factor binding);GO:0001158(enhancer sequence-specific DNA binding);GO:0001228(DNA-binding transcription activator activity, RNA polymerase II-specific);GO:0003151(outflow tract morphogenesis);GO:0003676(nucleic acid binding);GO:0003677(DNA binding);GO:0003682(chromatin binding);GO:0003700(DNA-binding transcription factor activity);GO:0004402(histone acetyltransferase activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0005739(mitochondrion);GO:0005741(mitochondrial outer membrane);GO:0006355(regulation of transcription, DNA-templated);GO:0006357(regulation of transcription by RNA polymerase II);GO:0006970(response to osmotic stress);GO:0006974(cellular response to DNA damage stimulus);GO:0008134(transcription factor binding);GO:0008140(cAMP response element binding protein binding);GO:0009414(response to water deprivation);GO:0010628(positive regulation of gene expression);GO:0016020(membrane);GO:0016525(negative regulation of angiogenesis);GO:0016573(histone acetylation);GO:0016740(transferase activity);GO:0019901(protein kinase binding);GO:0031573(intra-S DNA damage checkpoint);GO:0032915(positive regulation of transforming growth factor beta2 production);GO:0035497(cAMP response element binding);GO:0035861(site of double-strand break);GO:0043525(positive regulation of neuron apoptotic process);GO:0043565(sequence-specific DNA binding);GO:0045444(fat cell differentiation);GO:0045944(positive regulation of transcription by RNA polymerase II);GO:0046872(metal ion binding);GO:0046982(protein heterodimerization activity);GO:0050680(negative regulation of epithelial cell proliferation);GO:0051090(regulation of DNA-binding transcription factor activity);GO:0051091(positive regulation of DNA-binding transcription factor activity);GO:0060612(adipose tissue development);GO:0097186(amelogenesis);GO:0110024(positive regulation of cardiac muscle myoblast proliferation);GO:1902110(positive regulation of mitochondrial membrane permeability involved in apoptotic process)","04010(MAPK signaling pathway);04022(cGMP-PKG signaling pathway);04151(PI3K-Akt signaling pathway);04211(Longevity regulating pathway);04261(Adrenergic signaling in cardiomyocytes);04668(TNF signaling pathway);04714(Thermogenesis);04728(Dopaminergic synapse);04911(Insulin secretion);04915(Estrogen signaling pathway);04918(Thyroid hormone synthesis);04922(Glucagon signaling pathway);04925(Aldosterone synthesis and secretion);04926(Relaxin signaling pathway);04927(Cortisol synthesis and secretion);04928(Parathyroid hormone synthesis, secretion and action);04934(Cushing syndrome);05030(Cocaine addiction);05031(Amphetamine addiction);05034(Alcoholism);05161(Hepatitis B);05163(Human cytomegalovirus infection);05164(Influenza A);05166(Human T-cell leukemia virus 1 infection);05203(Viral carcinogenesis)","NA","NA","activating transcription factor 2 [Source:HGNC Symbol;Acc:HGNC:784]",{"v":1.563709,"d":"1.56"},{"v":0.884797,"d":"0.88"},0,0,0,0,"inf","inf",{"v":0.000281519523408746,"d":"0.00"},{"v":0.0246448296034692,"d":"0.02"},"up","yes"]
[8770,0,"chr1","+",101237498,101241189,"ENST00000649383",2,2636,"ENSG00000170989","S1PR1","GO:0001525(angiogenesis);GO:0001664(G protein-coupled receptor binding);GO:0001955(blood vessel maturation);GO:0003245(cardiac muscle tissue growth involved in heart morphogenesis);GO:0003376(sphingosine-1-phosphate receptor signaling pathway);GO:0004930(G protein-coupled receptor activity);GO:0005515(protein binding);GO:0005654(nucleoplasm);GO:0005768(endosome);GO:0005886(plasma membrane);GO:0006935(chemotaxis);GO:0007155(cell adhesion);GO:0007165(signal transduction);GO:0007186(G protein-coupled receptor signaling pathway);GO:0007193(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway);GO:0007420(brain development);GO:0008284(positive regulation of cell population proliferation);GO:0009897(external side of plasma membrane);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016477(cell migration);GO:0019221(cytokine-mediated signaling pathway);GO:0019226(transmission of nerve impulse);GO:0030032(lamellipodium assembly);GO:0030155(regulation of cell adhesion);GO:0030182(neuron differentiation);GO:0030335(positive regulation of cell migration);GO:0030500(regulation of bone mineralization);GO:0030595(leukocyte chemotaxis);GO:0031226(intrinsic component of plasma membrane);GO:0031532(actin cytoskeleton reorganization);GO:0038036(sphingosine-1-phosphate receptor activity);GO:0043231(intracellular membrane-bounded organelle);GO:0043547(positive regulation of GTPase activity);GO:0045121(membrane raft);GO:0045124(regulation of bone resorption);GO:0045446(endothelial cell differentiation);GO:0045944(positive regulation of transcription by RNA polymerase II);GO:0046625(sphingolipid binding);GO:0048661(positive regulation of smooth muscle cell proliferation);GO:0050927(positive regulation of positive chemotaxis);GO:0051482(positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway);GO:0051497(negative regulation of stress fiber assembly);GO:0061384(heart trabecula morphogenesis);GO:0072678(T cell migration)","04068(FoxO signaling pathway);04071(Sphingolipid signaling pathway);04080(Neuroactive ligand-receptor interaction)","K04288","NA","sphingosine-1-phosphate receptor 1 [Source:HGNC Symbol;Acc:HGNC:3165]",{"v":0.486423,"d":"0.49"},{"v":1.748331,"d":"1.75"},{"v":0.007157,"d":"0.01"},{"v":0.007976,"d":"0.01"},0,0,{"v":281.082121364092,"d":"281.08"},{"v":8.13484788170124,"d":"8.13"},{"v":0.000298052679969551,"d":"0.00"},{"v":0.0260294564021485,"d":"0.03"},"up","yes"]
[80401,0,"chr17","-",5443493,5468748,"ENST00000572490",11,2564,"ENSG00000005100","DHX33","GO:0000166(nucleotide binding);GO:0000182(rDNA binding);GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0003725(double-stranded RNA binding);GO:0003729(mRNA binding);GO:0004386(helicase activity);GO:0005515(protein binding);GO:0005524(ATP binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005730(nucleolus);GO:0005737(cytoplasm);GO:0006413(translational initiation);GO:0016787(hydrolase activity);GO:0032481(positive regulation of type I interferon production);GO:0033613(activating transcription factor binding);GO:0034459(ATP-dependent 3'-5' RNA helicase activity);GO:0043023(ribosomal large subunit binding);GO:0043410(positive regulation of MAPK cascade);GO:0045943(positive regulation of transcription by RNA polymerase I);GO:0051092(positive regulation of NF-kappaB transcription factor activity);GO:0061702(inflammasome complex);GO:0072559(NLRP3 inflammasome complex);GO:1900227(positive regulation of NLRP3 inflammasome complex assembly)","04621(NOD-like receptor signaling pathway)","K17820","EC:3.6.4.13","DEAH-box helicase 33 [Source:HGNC Symbol;Acc:HGNC:16718]",0,{"v":0.508543,"d":"0.51"},{"v":1.425115,"d":"1.43"},0,0,0,"inf","inf",{"v":0.000308704035609674,"d":"0.00"},{"v":0.0268760542927331,"d":"0.03"},"up","yes"]
[46365,0,"chr12","-",89519408,89526198,"ENST00000548729",3,5436,"ENSG00000259075","POC1B-GALNT4","GO:0000139(Golgi membrane);GO:0005794(Golgi apparatus);GO:0006486(protein glycosylation);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016740(transferase activity);GO:0016757(transferase activity, transferring glycosyl groups);GO:0030246(carbohydrate binding)","00512(Mucin type O-glycan biosynthesis)","K00710","EC:2.4.1.41","POC1B-GALNT4 readthrough [Source:HGNC Symbol;Acc:HGNC:42957]",0,0,0,{"v":0.27243,"d":"0.27"},{"v":0.595681,"d":"0.60"},0,"-inf","-inf",{"v":0.000309226278402489,"d":"0.00"},{"v":0.0268760542927331,"d":"0.03"},"down","yes"]
[182439,0,"chr7","-",102538417,102543849,"ENST00000644544",6,1005,"ENSG00000284981","AC093668","GO:0016020(membrane);GO:0016021(integral component of membrane)","NA","NA","NA","uroplakin 3B like 2 [Source:NCBI gene;Acc:107983993]",{"v":0.11172,"d":"0.11"},{"v":0.099558,"d":"0.10"},{"v":0.079833,"d":"0.08"},{"v":0.256957,"d":"0.26"},{"v":4.822174,"d":"4.82"},{"v":3.771165,"d":"3.77"},{"v":0.032892798161779,"d":"0.03"},{"v":-4.92608444756645,"d":"-4.93"},{"v":0.000318545546671205,"d":"0.00"},{"v":0.0276199515765272,"d":"0.03"},"down","yes"]
[134219,0,"chr22","-",36510899,36528897,"ENST00000405442",15,1851,"ENSG00000100353","EIF3D","GO:0001732(formation of cytoplasmic translation initiation complex);GO:0002183(cytoplasmic translational initiation);GO:0002191(cap-dependent translational initiation);GO:0003723(RNA binding);GO:0003743(translation initiation factor activity);GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005852(eukaryotic translation initiation factor 3 complex);GO:0006412(translation);GO:0006413(translational initiation);GO:0016020(membrane);GO:0016282(eukaryotic 43S preinitiation complex);GO:0033290(eukaryotic 48S preinitiation complex);GO:0045727(positive regulation of translation);GO:0071541(eukaryotic translation initiation factor 3 complex, eIF3m);GO:0075522(IRES-dependent viral translational initiation);GO:0075525(viral translational termination-reinitiation);GO:0098808(mRNA cap binding);GO:1902416(positive regulation of mRNA binding)","03013(RNA transport)","K03251","NA","eukaryotic translation initiation factor 3 subunit D [Source:HGNC Symbol;Acc:HGNC:3278]",{"v":0.18803,"d":"0.19"},0,0,{"v":24.999285,"d":"25.00"},{"v":0.151433,"d":"0.15"},{"v":9.175271,"d":"9.18"},{"v":0.00547777370668038,"d":"0.01"},{"v":-7.51219461682861,"d":"-7.51"},{"v":0.000320826339903346,"d":"0.00"},{"v":0.0277514784016394,"d":"0.03"},"down","yes"]
[148265,0,"chr3","-",195568908,195583940,"ENST00000421243",6,782,"ENSG00000189058","APOD","GO:0000302(response to reactive oxygen species);GO:0001525(angiogenesis);GO:0005319(lipid transporter activity);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0005615(extracellular space);GO:0005737(cytoplasm);GO:0005783(endoplasmic reticulum);GO:0006006(glucose metabolic process);GO:0006629(lipid metabolic process);GO:0006869(lipid transport);GO:0007420(brain development);GO:0007568(aging);GO:0008289(lipid binding);GO:0010642(negative regulation of platelet-derived growth factor receptor signaling pathway);GO:0014012(peripheral nervous system axon regeneration);GO:0015485(cholesterol binding);GO:0022626(cytosolic ribosome);GO:0030425(dendrite);GO:0042246(tissue regeneration);GO:0042308(negative regulation of protein import into nucleus);GO:0042493(response to drug);GO:0043025(neuronal cell body);GO:0048471(perinuclear region of cytoplasm);GO:0048662(negative regulation of smooth muscle cell proliferation);GO:0048678(response to axon injury);GO:0051895(negative regulation of focal adhesion assembly);GO:0060588(negative regulation of lipoprotein lipid oxidation);GO:0070062(extracellular exosome);GO:0071638(negative regulation of monocyte chemotactic protein-1 production);GO:1900016(negative regulation of cytokine production involved in inflammatory response);GO:2000098(negative regulation of smooth muscle cell-matrix adhesion);GO:2000405(negative regulation of T cell migration)","NA","NA","NA","apolipoprotein D [Source:HGNC Symbol;Acc:HGNC:612]",0,0,{"v":0.016736,"d":"0.02"},{"v":9.994156,"d":"9.99"},{"v":2.179417,"d":"2.18"},0,{"v":0.00137478125772935,"d":"0.00"},{"v":-9.5065821958384,"d":"-9.51"},{"v":0.00032349814015158,"d":"0.00"},{"v":0.0279161221655746,"d":"0.03"},"down","yes"]
[11973,0,"chr1","+",155174754,155184951,"ENST00000468878",12,3318,"ENSG00000163462","TRIM46","GO:0000226(microtubule cytoskeleton organization);GO:0001578(microtubule bundle formation);GO:0001764(neuron migration);GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0005856(cytoskeleton);GO:0007409(axonogenesis);GO:0008270(zinc ion binding);GO:0030424(axon);GO:0030517(negative regulation of axon extension);GO:0042995(cell projection);GO:0043194(axon initial segment);GO:0044304(main axon);GO:0046872(metal ion binding);GO:0048490(anterograde synaptic vesicle transport);GO:0099612(protein localization to axon);GO:1901953(positive regulation of anterograde dense core granule transport);GO:1903827(regulation of cellular protein localization);GO:1904115(axon cytoplasm);GO:1990769(proximal neuron projection)","NA","K12022","NA","tripartite motif containing 46 [Source:HGNC Symbol;Acc:HGNC:19019]",{"v":0.873917,"d":"0.87"},{"v":0.053862,"d":"0.05"},{"v":0.810137,"d":"0.81"},{"v":0.007803,"d":"0.01"},0,{"v":0.012317,"d":"0.01"},{"v":86.3775347912525,"d":"86.38"},{"v":6.43258423760518,"d":"6.43"},{"v":0.000324327569574609,"d":"0.00"},{"v":0.027921375835653,"d":"0.03"},"up","yes"]
[147245,0,"chr3","+",184135379,184145290,"ENST00000648599",17,2613,"ENSG00000145191","EIF2B5","GO:0001541(ovarian follicle development);GO:0003743(translation initiation factor activity);GO:0005085(guanyl-nucleotide exchange factor activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005851(eukaryotic translation initiation factor 2B complex);GO:0006412(translation);GO:0006413(translational initiation);GO:0007568(aging);GO:0009408(response to heat);GO:0009749(response to glucose);GO:0010226(response to lithium ion);GO:0014002(astrocyte development);GO:0014003(oligodendrocyte development);GO:0021766(hippocampus development);GO:0031369(translation initiation factor binding);GO:0034976(response to endoplasmic reticulum stress);GO:0042552(myelination);GO:0043065(positive regulation of apoptotic process);GO:0043434(response to peptide hormone);GO:0045727(positive regulation of translation);GO:0045948(positive regulation of translational initiation);GO:0048708(astrocyte differentiation);GO:0050852(T cell receptor signaling pathway)","03013(RNA transport);05168(Herpes simplex virus 1 infection)","K03240","NA","eukaryotic translation initiation factor 2B subunit epsilon [Source:HGNC Symbol;Acc:HGNC:3261]",{"v":0.979479,"d":"0.98"},{"v":0.754322,"d":"0.75"},0,0,0,0,"inf","inf",{"v":0.000326885703433641,"d":"0.00"},{"v":0.0280750770821376,"d":"0.03"},"up","yes"]
[84393,0,"chr17","+",35587322,35670898,"ENST00000612035",15,2161,"ENSG00000006125","AP2B1","GO:0003279(cardiac septum development);GO:0003281(ventricular septum development);GO:0005048(signal sequence binding);GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0005905(clathrin-coated pit);GO:0006886(intracellular protein transport);GO:0006897(endocytosis);GO:0007507(heart development);GO:0015031(protein transport);GO:0016020(membrane);GO:0016192(vesicle-mediated transport);GO:0019886(antigen processing and presentation of exogenous peptide antigen via MHC class II);GO:0030117(membrane coat);GO:0030118(clathrin coat);GO:0030122(AP-2 adaptor complex);GO:0030131(clathrin adaptor complex);GO:0030276(clathrin binding);GO:0030666(endocytic vesicle membrane);GO:0030669(clathrin-coated endocytic vesicle membrane);GO:0032802(low-density lipoprotein particle receptor catabolic process);GO:0034383(low-density lipoprotein particle clearance);GO:0035615(clathrin adaptor activity);GO:0035904(aorta development);GO:0036020(endolysosome membrane);GO:0038024(cargo receptor activity);GO:0044877(protein-containing complex binding);GO:0045334(clathrin-coated endocytic vesicle);GO:0045807(positive regulation of endocytosis);GO:0048013(ephrin receptor signaling pathway);GO:0048268(clathrin coat assembly);GO:0050690(regulation of defense response to virus by virus);GO:0060071(Wnt signaling pathway, planar cell polarity pathway);GO:0060976(coronary vasculature development);GO:0061024(membrane organization);GO:0072583(clathrin-dependent endocytosis);GO:0098794(postsynapse);GO:0098884(postsynaptic neurotransmitter receptor internalization);GO:0098978(glutamatergic synapse);GO:0099590(neurotransmitter receptor internalization);GO:1901215(negative regulation of neuron death);GO:1905477(positive regulation of protein localization to membrane)","04144(Endocytosis);04721(Synaptic vesicle cycle);04961(Endocrine and other factor-regulated calcium reabsorption);05016(Huntington disease)","NA","NA","adaptor related protein complex 2 subunit beta 1 [Source:HGNC Symbol;Acc:HGNC:563]",{"v":0.045311,"d":"0.05"},{"v":0.072413,"d":"0.07"},{"v":0.001322,"d":"0.00"},{"v":0.073439,"d":"0.07"},{"v":0.948911,"d":"0.95"},{"v":8.335115,"d":"8.34"},{"v":0.0127220352948154,"d":"0.01"},{"v":-6.29652669565825,"d":"-6.30"},{"v":0.000332349661160563,"d":"0.00"},{"v":0.028477035825385,"d":"0.03"},"down","yes"]
[90791,0,"chr17","-",76734577,76737331,"ENST00000508921",3,1390,"ENSG00000161547","SRSF2","GO:0000278(mitotic cell cycle);GO:0000381(regulation of alternative mRNA splicing, via spliceosome);GO:0000398(mRNA splicing, via spliceosome);GO:0003676(nucleic acid binding);GO:0003714(transcription corepressor activity);GO:0003723(RNA binding);GO:0005080(protein kinase C binding);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005681(spliceosomal complex);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0006397(mRNA processing);GO:0006405(RNA export from nucleus);GO:0006406(mRNA export from nucleus);GO:0008380(RNA splicing);GO:0016607(nuclear speck);GO:0031124(mRNA 3'-end processing);GO:0033197(response to vitamin E);GO:0035061(interchromatin granule);GO:0036002(pre-mRNA binding);GO:0043484(regulation of RNA splicing);GO:0045292(mRNA cis splicing, via spliceosome);GO:1903507(negative regulation of nucleic acid-templated transcription)","03040(Spliceosome);05168(Herpes simplex virus 1 infection)","K12891","NA","serine and arginine rich splicing factor 2 [Source:HGNC Symbol;Acc:HGNC:10783]",0,{"v":1.655256,"d":"1.66"},{"v":1.582382,"d":"1.58"},0,0,0,"inf","inf",{"v":0.000334995656923816,"d":"0.00"},{"v":0.0285709584629512,"d":"0.03"},"up","yes"]
[125924,0,"chr20","+",32109736,32167258,"ENST00000217315",18,4032,"ENSG00000101337","TM9SF4","GO:0001666(response to hypoxia);GO:0005515(protein binding);GO:0005768(endosome);GO:0005769(early endosome);GO:0005794(Golgi apparatus);GO:0006909(phagocytosis);GO:0007155(cell adhesion);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0051453(regulation of intracellular pH);GO:0070072(vacuolar proton-transporting V-type ATPase complex assembly);GO:0070863(positive regulation of protein exit from endoplasmic reticulum);GO:0072657(protein localization to membrane);GO:2000010(positive regulation of protein localization to cell surface)","NA","K17086","NA","transmembrane 9 superfamily member 4 [Source:HGNC Symbol;Acc:HGNC:30797]",{"v":0.071669,"d":"0.07"},0,0,{"v":1.66389,"d":"1.66"},{"v":6.774029,"d":"6.77"},{"v":0.322993,"d":"0.32"},{"v":0.00818054102130007,"d":"0.01"},{"v":-6.93358802548823,"d":"-6.93"},{"v":0.000335018670663838,"d":"0.00"},{"v":0.0285709584629512,"d":"0.03"},"down","yes"]
[92015,0,"chr17","-",82061258,82065797,"ENST00000578176",7,937,"ENSG00000169718","DUS1L","GO:0002943(tRNA dihydrouridine synthesis);GO:0003824(catalytic activity);GO:0008033(tRNA processing);GO:0016491(oxidoreductase activity);GO:0017150(tRNA dihydrouridine synthase activity);GO:0050660(flavin adenine dinucleotide binding);GO:0055114(oxidation-reduction process)","NA","K05542","EC:1.3.1.88","dihydrouridine synthase 1 like [Source:HGNC Symbol;Acc:HGNC:30086]",{"v":1.709076,"d":"1.71"},{"v":3.183846,"d":"3.18"},0,0,0,0,"inf","inf",{"v":0.000336760108956524,"d":"0.00"},{"v":0.0286369242524956,"d":"0.03"},"up","yes"]
[178777,0,"chr7","-",45100101,45111706,"ENST00000494076",11,2190,"ENSG00000136270","TBRG4","GO:0003723(RNA binding);GO:0004672(protein kinase activity);GO:0005515(protein binding);GO:0005739(mitochondrion);GO:0005759(mitochondrial matrix);GO:0006468(protein phosphorylation);GO:0007050(cell cycle arrest);GO:0008284(positive regulation of cell population proliferation);GO:0016071(mRNA metabolic process);GO:0044528(regulation of mitochondrial mRNA stability);GO:0045333(cellular respiration);GO:0090615(mitochondrial mRNA processing)","NA","NA","NA","transforming growth factor beta regulator 4 [Source:HGNC Symbol;Acc:HGNC:17443]",{"v":1.224315,"d":"1.22"},{"v":0.822636,"d":"0.82"},0,0,0,0,"inf","inf",{"v":0.000337368664466505,"d":"0.00"},{"v":0.0286369242524956,"d":"0.03"},"up","yes"]
[28931,0,"chr11","+",33257587,33357023,"ENST00000379016",16,7345,"ENSG00000110422","HIPK3","GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005524(ATP binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0006468(protein phosphorylation);GO:0006915(apoptotic process);GO:0009299(mRNA transcription);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0016604(nuclear body);GO:0016605(PML body);GO:0016740(transferase activity);GO:0018105(peptidyl-serine phosphorylation);GO:0018107(peptidyl-threonine phosphorylation);GO:0043066(negative regulation of apoptotic process);GO:0043508(negative regulation of JUN kinase activity)","04218(Cellular senescence)","K08826","EC:2.7.11.1","homeodomain interacting protein kinase 3 [Source:HGNC Symbol;Acc:HGNC:4915]",{"v":2.063541,"d":"2.06"},{"v":0.967784,"d":"0.97"},{"v":0.510394,"d":"0.51"},{"v":7.536695,"d":"7.54"},{"v":8.703763,"d":"8.70"},{"v":8.995409,"d":"9.00"},{"v":0.140344653108213,"d":"0.14"},{"v":-2.83295399420905,"d":"-2.83"},{"v":0.000340212338142738,"d":"0.00"},{"v":0.0288109889154445,"d":"0.03"},"down","yes"]
[41241,0,"chr12","+",28190427,28550166,"ENST00000539107",12,2440,"ENSG00000123106","CCDC91","GO:0005654(nucleoplasm);GO:0005794(Golgi apparatus);GO:0005802(trans-Golgi network);GO:0005829(cytosol);GO:0015031(protein transport);GO:0016020(membrane);GO:0042802(identical protein binding);GO:0048193(Golgi vesicle transport);GO:0090160(Golgi to lysosome transport)","NA","NA","NA","coiled-coil domain containing 91 [Source:HGNC Symbol;Acc:HGNC:24855]",0,0,0,0,{"v":0.509519,"d":"0.51"},{"v":1.387205,"d":"1.39"},"-inf","-inf",{"v":0.000342464807872077,"d":"0.00"},{"v":0.0289342941162617,"d":"0.03"},"down","yes"]
[182168,0,"chr7","-",100802565,100827115,"ENST00000360620",16,3789,"ENSG00000196411","EPHB4","GO:0000166(nucleotide binding);GO:0001525(angiogenesis);GO:0002042(cell migration involved in sprouting angiogenesis);GO:0003007(heart morphogenesis);GO:0004672(protein kinase activity);GO:0004713(protein tyrosine kinase activity);GO:0004714(transmembrane receptor protein tyrosine kinase activity);GO:0005003(ephrin receptor activity);GO:0005005(transmembrane-ephrin receptor activity);GO:0005515(protein binding);GO:0005524(ATP binding);GO:0005576(extracellular region);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0005887(integral component of plasma membrane);GO:0006468(protein phosphorylation);GO:0007155(cell adhesion);GO:0007169(transmembrane receptor protein tyrosine kinase signaling pathway);GO:0007275(multicellular organism development);GO:0007411(axon guidance);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0016740(transferase activity);GO:0018108(peptidyl-tyrosine phosphorylation);GO:0043005(neuron projection);GO:0043235(receptor complex);GO:0046777(protein autophosphorylation);GO:0048013(ephrin receptor signaling pathway);GO:0070062(extracellular exosome)","04360(Axon guidance)","K05113","EC:2.7.10.1","EPH receptor B4 [Source:HGNC Symbol;Acc:HGNC:3395]",{"v":0.768314,"d":"0.77"},{"v":0.419694,"d":"0.42"},0,0,0,0,"inf","inf",{"v":0.000344066252810556,"d":"0.00"},{"v":0.0290021507299478,"d":"0.03"},"up","yes"]
[65828,0,"chr15","+",69414293,69448132,"ENST00000395392",23,3357,"ENSG00000137807","KIF23","GO:0000022(mitotic spindle elongation);GO:0000166(nucleotide binding);GO:0000281(mitotic cytokinesis);GO:0000915(actomyosin contractile ring assembly);GO:0003774(motor activity);GO:0003777(microtubule motor activity);GO:0005515(protein binding);GO:0005524(ATP binding);GO:0005623(cell);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0005813(centrosome);GO:0005819(spindle);GO:0005829(cytosol);GO:0005856(cytoskeleton);GO:0005871(kinesin complex);GO:0005874(microtubule);GO:0005925(focal adhesion);GO:0006890(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum);GO:0007018(microtubule-based movement);GO:0007049(cell cycle);GO:0008017(microtubule binding);GO:0016887(ATPase activity);GO:0019886(antigen processing and presentation of exogenous peptide antigen via MHC class II);GO:0030496(midbody);GO:0032467(positive regulation of cytokinesis);GO:0045171(intercellular bridge);GO:0051256(mitotic spindle midzone assembly);GO:0051301(cell division);GO:0072383(plus-end-directed vesicle transport along microtubule);GO:0072686(mitotic spindle);GO:0090543(Flemming body);GO:0097149(centralspindlin complex)","05206(MicroRNAs in cancer)","K17387","NA","kinesin family member 23 [Source:HGNC Symbol;Acc:HGNC:6392]",0,0,0,{"v":0.658052,"d":"0.66"},{"v":0.628953,"d":"0.63"},0,"-inf","-inf",{"v":0.000349446665410084,"d":"0.00"},{"v":0.0293874938758063,"d":"0.03"},"down","yes"]
[170581,0,"chr6","-",41934956,41941519,"ENST00000372987",5,2233,"ENSG00000112576","CCND3","GO:0000079(regulation of cyclin-dependent protein serine/threonine kinase activity);GO:0000122(negative regulation of transcription by RNA polymerase II);GO:0000278(mitotic cell cycle);GO:0000307(cyclin-dependent protein kinase holoenzyme complex);GO:0001934(positive regulation of protein phosphorylation);GO:0004672(protein kinase activity);GO:0004693(cyclin-dependent protein serine/threonine kinase activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0006468(protein phosphorylation);GO:0007049(cell cycle);GO:0007088(regulation of mitotic nuclear division);GO:0007165(signal transduction);GO:0008284(positive regulation of cell population proliferation);GO:0016020(membrane);GO:0016538(cyclin-dependent protein serine/threonine kinase regulator activity);GO:0019901(protein kinase binding);GO:0042098(T cell proliferation);GO:0042127(regulation of cell population proliferation);GO:0045737(positive regulation of cyclin-dependent protein serine/threonine kinase activity);GO:0045787(positive regulation of cell cycle);GO:0046626(regulation of insulin receptor signaling pathway);GO:0051301(cell division);GO:0051726(regulation of cell cycle);GO:1900087(positive regulation of G1/S transition of mitotic cell cycle)","04110(Cell cycle);04115(p53 signaling pathway);04151(PI3K-Akt signaling pathway);04218(Cellular senescence);04310(Wnt signaling pathway);04390(Hippo signaling pathway);04510(Focal adhesion);04630(Jak-STAT signaling pathway);05162(Measles);05165(Human papillomavirus infection);05166(Human T-cell leukemia virus 1 infection);05169(Epstein-Barr virus infection);05200(Pathways in cancer);05203(Viral carcinogenesis)","NA","NA","cyclin D3 [Source:HGNC Symbol;Acc:HGNC:1585]",{"v":0.018805,"d":"0.02"},{"v":0.046534,"d":"0.05"},{"v":0.267606,"d":"0.27"},{"v":16.125732,"d":"16.13"},{"v":0.023232,"d":"0.02"},{"v":8.391654,"d":"8.39"},{"v":0.0135670992474599,"d":"0.01"},{"v":-6.20374389559534,"d":"-6.20"},{"v":0.000358658569252435,"d":"0.00"},{"v":0.0300925307642978,"d":"0.03"},"down","yes"]
[196483,0,"chr9","+",69205155,69255187,"ENST00000649134",21,3964,"ENSG00000119139","TJP2","GO:0004385(guanylate kinase activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0005912(adherens junction);GO:0005923(bicellular tight junction);GO:0016020(membrane);GO:0019904(protein domain specific binding);GO:0030054(cell junction);GO:0030674(protein binding, bridging);GO:0035329(hippo signaling);GO:0045296(cadherin binding);GO:0046037(GMP metabolic process);GO:0046710(GDP metabolic process);GO:0050892(intestinal absorption);GO:0090557(establishment of endothelial intestinal barrier);GO:0090559(regulation of membrane permeability)","04530(Tight junction);05110(Vibrio cholerae infection)","K06098","NA","tight junction protein 2 [Source:HGNC Symbol;Acc:HGNC:11828]",{"v":0.242413,"d":"0.24"},0,{"v":0.97388,"d":"0.97"},0,0,0,"inf","inf",{"v":0.000361142234070862,"d":"0.00"},{"v":0.030231099916577,"d":"0.03"},"up","yes"]
[170832,0,"chr6","-",43512761,43516919,"ENST00000455768",7,843,"ENSG00000137207","YIPF3","GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0005794(Golgi apparatus);GO:0005886(plasma membrane);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0030133(transport vesicle);GO:0030154(cell differentiation);GO:0043231(intracellular membrane-bounded organelle)","NA","K22941","NA","Yip1 domain family member 3 [Source:HGNC Symbol;Acc:HGNC:21023]",{"v":1.357584,"d":"1.36"},0,{"v":4.126614,"d":"4.13"},0,0,0,"inf","inf",{"v":0.000366331951376313,"d":"0.00"},{"v":0.0305950340080493,"d":"0.03"},"up","yes"]
[82675,0,"chr17","+",19283047,19334330,"ENST00000571254",8,1883,"ENSG00000072134","EPN2","GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0006897(endocytosis);GO:0008289(lipid binding);GO:0030128(clathrin coat of endocytic vesicle);GO:0030136(clathrin-coated vesicle);GO:0030948(negative regulation of vascular endothelial growth factor receptor signaling pathway);GO:0031410(cytoplasmic vesicle);GO:0043231(intracellular membrane-bounded organelle);GO:0045296(cadherin binding);GO:0045747(positive regulation of Notch signaling pathway);GO:0061024(membrane organization);GO:1903671(negative regulation of sprouting angiogenesis)","04144(Endocytosis)","K12471","NA","epsin 2 [Source:HGNC Symbol;Acc:HGNC:18639]",0,0,0,0,{"v":0.904394,"d":"0.90"},{"v":1.398829,"d":"1.40"},"-inf","-inf",{"v":0.000368468393531647,"d":"0.00"},{"v":0.0307028824243228,"d":"0.03"},"down","yes"]
[150933,0,"chr4","+",41256769,41268256,"ENST00000503431",10,917,"ENSG00000154277","UCHL1","GO:0002931(response to ischemia);GO:0004197(cysteine-type endopeptidase activity);GO:0004843(thiol-dependent ubiquitin-specific protease activity);GO:0005515(protein binding);GO:0005622(intracellular);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0006508(proteolysis);GO:0006511(ubiquitin-dependent protein catabolic process);GO:0007409(axonogenesis);GO:0007412(axon target recognition);GO:0007628(adult walking behavior);GO:0008233(peptidase activity);GO:0008234(cysteine-type peptidase activity);GO:0008242(omega peptidase activity);GO:0008283(cell population proliferation);GO:0016020(membrane);GO:0016241(regulation of macroautophagy);GO:0016579(protein deubiquitination);GO:0016787(hydrolase activity);GO:0016874(ligase activity);GO:0019233(sensory perception of pain);GO:0019896(axonal transport of mitochondrion);GO:0030424(axon);GO:0031625(ubiquitin protein ligase binding);GO:0031694(alpha-2A adrenergic receptor binding);GO:0036459(thiol-dependent ubiquitinyl hydrolase activity);GO:0042755(eating behavior);GO:0043025(neuronal cell body);GO:0043130(ubiquitin binding);GO:0043161(proteasome-mediated ubiquitin-dependent protein catabolic process);GO:0043407(negative regulation of MAP kinase activity);GO:0044306(neuron projection terminus);GO:0048747(muscle fiber development);GO:0050905(neuromuscular process);GO:1904115(axon cytoplasm)","05012(Parkinson disease)","K05611","EC:3.4.19.12","ubiquitin C-terminal hydrolase L1 [Source:HGNC Symbol;Acc:HGNC:12513]",{"v":1.387159,"d":"1.39"},{"v":3.531991,"d":"3.53"},0,0,0,0,"inf","inf",{"v":0.000369753570442012,"d":"0.00"},{"v":0.0307394673092867,"d":"0.03"},"up","yes"]
[48712,0,"chr12","-",120196707,120201110,"ENST00000552461",6,2591,"ENSG00000089157","RPLP0","GO:0000027(ribosomal large subunit assembly);GO:0000184(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay);GO:0002181(cytoplasmic translation);GO:0003723(RNA binding);GO:0003735(structural constituent of ribosome);GO:0005515(protein binding);GO:0005622(intracellular);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005783(endoplasmic reticulum);GO:0005829(cytosol);GO:0005840(ribosome);GO:0005925(focal adhesion);GO:0006412(translation);GO:0006413(translational initiation);GO:0006614(SRP-dependent cotranslational protein targeting to membrane);GO:0014069(postsynaptic density);GO:0016020(membrane);GO:0019083(viral transcription);GO:0022625(cytosolic large ribosomal subunit);GO:0035722(interleukin-12-mediated signaling pathway);GO:0036464(cytoplasmic ribonucleoprotein granule);GO:0042254(ribosome biogenesis);GO:0070062(extracellular exosome);GO:0070180(large ribosomal subunit rRNA binding);GO:0098794(postsynapse);GO:1990904(ribonucleoprotein complex)","03010(Ribosome)","K02941","NA","ribosomal protein lateral stalk subunit P0 [Source:HGNC Symbol;Acc:HGNC:10371]",{"v":1.854881,"d":"1.85"},{"v":1.135527,"d":"1.14"},{"v":0.910202,"d":"0.91"},{"v":0.834532,"d":"0.83"},{"v":159.150467,"d":"159.15"},{"v":1.840151,"d":"1.84"},{"v":0.0241038553030848,"d":"0.02"},{"v":-5.37459227229014,"d":"-5.37"},{"v":0.000373412497363148,"d":"0.00"},{"v":0.0309727763223817,"d":"0.03"},"down","yes"]
[1291,0,"chr1","-",8861000,8878686,"ENST00000234590",12,1781,"ENSG00000074800","ENO1","GO:0000015(phosphopyruvate hydratase complex);GO:0000122(negative regulation of transcription by RNA polymerase II);GO:0000287(magnesium ion binding);GO:0000977(RNA polymerase II regulatory region sequence-specific DNA binding);GO:0001227(DNA-binding transcription repressor activity, RNA polymerase II-specific);GO:0003677(DNA binding);GO:0003723(RNA binding);GO:0004634(phosphopyruvate hydratase activity);GO:0005515(protein binding);GO:0005615(extracellular space);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0006094(gluconeogenesis);GO:0006096(glycolytic process);GO:0009615(response to virus);GO:0009986(cell surface);GO:0010756(positive regulation of plasminogen activation);GO:0016020(membrane);GO:0016829(lyase activity);GO:0030308(negative regulation of cell growth);GO:0031430(M band);GO:0042803(protein homodimerization activity);GO:0045296(cadherin binding);GO:0045892(negative regulation of transcription, DNA-templated);GO:0045933(positive regulation of muscle contraction);GO:0046872(metal ion binding);GO:0051020(GTPase binding);GO:0061621(canonical glycolysis);GO:0070062(extracellular exosome);GO:0099738(cell cortex region);GO:1903298(negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway);GO:2001171(positive regulation of ATP biosynthetic process)","00010(Glycolysis / Gluconeogenesis);03018(RNA degradation);04066(HIF-1 signaling pathway)","NA","NA","enolase 1 [Source:HGNC Symbol;Acc:HGNC:3350]",{"v":0.007872,"d":"0.01"},{"v":375.086243,"d":"375.09"},{"v":0.819963,"d":"0.82"},{"v":0.185347,"d":"0.19"},{"v":1.003723,"d":"1.00"},{"v":0.069365,"d":"0.07"},{"v":298.715530003536,"d":"298.72"},{"v":8.22262843404099,"d":"8.22"},{"v":0.000379037628804896,"d":"0.00"},{"v":0.0313677381651068,"d":"0.03"},"up","yes"]
[157468,0,"chr5","+",7869148,7901124,"ENST00000511461",14,3076,"ENSG00000124275","MTRR","GO:0000096(sulfur amino acid metabolic process);GO:0003958(NADPH-hemoprotein reductase activity);GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0006306(DNA methylation);GO:0006555(methionine metabolic process);GO:0008652(cellular amino acid biosynthetic process);GO:0009086(methionine biosynthetic process);GO:0009235(cobalamin metabolic process);GO:0010181(FMN binding);GO:0016491(oxidoreductase activity);GO:0016723(oxidoreductase activity, oxidizing metal ions, NAD or NADP as acceptor);GO:0030586([methionine synthase] reductase activity);GO:0032259(methylation);GO:0033353(S-adenosylmethionine cycle);GO:0043418(homocysteine catabolic process);GO:0046655(folic acid metabolic process);GO:0050444(aquacobalamin reductase (NADPH) activity);GO:0050660(flavin adenine dinucleotide binding);GO:0050661(NADP binding);GO:0050667(homocysteine metabolic process);GO:0055114(oxidation-reduction process);GO:0070402(NADPH binding);GO:0071949(FAD binding);GO:1904042(negative regulation of cystathionine beta-synthase activity)","NA","K00597","EC:1.16.1.8","5-methyltetrahydrofolate-homocysteine methyltransferase reductase [Source:HGNC Symbol;Acc:HGNC:7473]",{"v":6.16245,"d":"6.16"},{"v":4.344962,"d":"4.34"},{"v":2.084417,"d":"2.08"},{"v":0.067118,"d":"0.07"},{"v":0.025196,"d":"0.03"},{"v":0.438528,"d":"0.44"},{"v":23.7204836844108,"d":"23.72"},{"v":4.5680615230675,"d":"4.57"},{"v":0.000387627557669126,"d":"0.00"},{"v":0.0320057026593622,"d":"0.03"},"up","yes"]
[7048,0,"chr1","+",63774017,64181498,"ENST00000371079",9,5858,"ENSG00000185483","ROR1","GO:0000166(nucleotide binding);GO:0001725(stress fiber);GO:0004672(protein kinase activity);GO:0004714(transmembrane receptor protein tyrosine kinase activity);GO:0005515(protein binding);GO:0005524(ATP binding);GO:0005737(cytoplasm);GO:0005886(plasma membrane);GO:0005887(integral component of plasma membrane);GO:0006468(protein phosphorylation);GO:0007169(transmembrane receptor protein tyrosine kinase signaling pathway);GO:0007605(sensory perception of sound);GO:0009986(cell surface);GO:0014002(astrocyte development);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016055(Wnt signaling pathway);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0016740(transferase activity);GO:0017147(Wnt-protein binding);GO:0018108(peptidyl-tyrosine phosphorylation);GO:0030424(axon);GO:0042813(Wnt-activated receptor activity);GO:0042995(cell projection);GO:0043123(positive regulation of I-kappaB kinase/NF-kappaB signaling);GO:0043235(receptor complex);GO:0043679(axon terminus);GO:0048839(inner ear development);GO:0048856(anatomical structure development);GO:0051092(positive regulation of NF-kappaB transcription factor activity);GO:0060071(Wnt signaling pathway, planar cell polarity pathway);GO:1904929(coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway)","04310(Wnt signaling pathway)","K05122","EC:2.7.10.1","receptor tyrosine kinase like orphan receptor 1 [Source:HGNC Symbol;Acc:HGNC:10256]",{"v":0.009247,"d":"0.01"},{"v":0.018893,"d":"0.02"},{"v":0.013509,"d":"0.01"},{"v":0.061967,"d":"0.06"},{"v":0.14418,"d":"0.14"},{"v":1.294269,"d":"1.29"},{"v":0.0277583016976625,"d":"0.03"},{"v":-5.17093688581066,"d":"-5.17"},{"v":0.000388653229822097,"d":"0.00"},{"v":0.0320176232186775,"d":"0.03"},"down","yes"]
[75335,0,"chr16","+",57123306,57147964,"ENST00000566042",5,3446,"ENSG00000140848","CPNE2","GO:0005515(protein binding);GO:0005544(calcium-dependent phospholipid binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005886(plasma membrane);GO:0016020(membrane);GO:0070062(extracellular exosome);GO:0071277(cellular response to calcium ion)","NA","NA","NA","copine 2 [Source:HGNC Symbol;Acc:HGNC:2315]",{"v":0.057796,"d":"0.06"},{"v":0.019833,"d":"0.02"},{"v":0.038235,"d":"0.04"},{"v":0.686402,"d":"0.69"},{"v":0.522656,"d":"0.52"},{"v":0.706725,"d":"0.71"},{"v":0.0604786659031842,"d":"0.06"},{"v":-4.04742987422514,"d":"-4.05"},{"v":0.000395633892087834,"d":"0.00"},{"v":0.0324468390740414,"d":"0.03"},"down","yes"]
[11894,0,"chr1","+",155051286,155062758,"ENST00000356955",23,2949,"ENSG00000143537","ADAM15","GO:0001525(angiogenesis);GO:0001669(acrosomal vesicle);GO:0001953(negative regulation of cell-matrix adhesion);GO:0002418(immune response to tumor cell);GO:0004222(metalloendopeptidase activity);GO:0005178(integrin binding);GO:0005515(protein binding);GO:0005886(plasma membrane);GO:0005912(adherens junction);GO:0005929(cilium);GO:0006508(proteolysis);GO:0007155(cell adhesion);GO:0007160(cell-matrix adhesion);GO:0007229(integrin-mediated signaling pathway);GO:0008233(peptidase activity);GO:0008237(metallopeptidase activity);GO:0008584(male gonad development);GO:0009986(cell surface);GO:0012505(endomembrane system);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016787(hydrolase activity);GO:0017124(SH3 domain binding);GO:0022617(extracellular matrix disassembly);GO:0030054(cell junction);GO:0030198(extracellular matrix organization);GO:0030308(negative regulation of cell growth);GO:0030336(negative regulation of cell migration);GO:0030574(collagen catabolic process);GO:0031410(cytoplasmic vesicle);GO:0031514(motile cilium);GO:0042246(tissue regeneration);GO:0042995(cell projection);GO:0045087(innate immune response);GO:0046872(metal ion binding);GO:0060317(cardiac epithelial to mesenchymal transition);GO:0070062(extracellular exosome);GO:1900121(negative regulation of receptor binding);GO:1904628(cellular response to phorbol 13-acetate 12-myristate);GO:1990910(response to hypobaric hypoxia)","NA","K06836","EC:3.4.24.-","ADAM metallopeptidase domain 15 [Source:HGNC Symbol;Acc:HGNC:193]",0,0,0,{"v":0.688559,"d":"0.69"},0,{"v":0.664172,"d":"0.66"},"-inf","-inf",{"v":0.000395649592892935,"d":"0.00"},{"v":0.0324468390740414,"d":"0.03"},"down","yes"]
[112732,0,"chr2","+",60781975,60802085,"ENST00000412217",11,6074,"ENSG00000115421","PAPOLG","GO:0000166(nucleotide binding);GO:0003723(RNA binding);GO:0004652(polynucleotide adenylyltransferase activity);GO:0005524(ATP binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0006378(mRNA polyadenylation);GO:0006397(mRNA processing);GO:0016020(membrane);GO:0016604(nuclear body);GO:0016740(transferase activity);GO:0016779(nucleotidyltransferase activity);GO:0031123(RNA 3'-end processing);GO:0043631(RNA polyadenylation);GO:0046872(metal ion binding)","03015(mRNA surveillance pathway)","K14376","EC:2.7.7.19","poly(A) polymerase gamma [Source:HGNC Symbol;Acc:HGNC:14982]",0,0,0,{"v":0.165693,"d":"0.17"},{"v":0.568029,"d":"0.57"},0,"-inf","-inf",{"v":0.000398299484315758,"d":"0.00"},{"v":0.0325905861828637,"d":"0.03"},"down","yes"]
[40687,0,"chr12","+",19129768,19376400,"ENST00000429027",32,4762,"ENSG00000052126","PLEKHA5","GO:0005515(protein binding);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0008150(biological_process);GO:0010314(phosphatidylinositol-5-phosphate binding);GO:0014069(postsynaptic density);GO:0016020(membrane);GO:0032266(phosphatidylinositol-3-phosphate binding);GO:0061458(reproductive system development);GO:0070273(phosphatidylinositol-4-phosphate binding);GO:0080025(phosphatidylinositol-3,5-bisphosphate binding);GO:0098978(glutamatergic synapse)","NA","NA","NA","pleckstrin homology domain containing A5 [Source:HGNC Symbol;Acc:HGNC:30036]",{"v":6.196314,"d":"6.20"},{"v":4.885177,"d":"4.89"},{"v":1.068053,"d":"1.07"},{"v":0.193062,"d":"0.19"},{"v":0.503724,"d":"0.50"},{"v":0.229859,"d":"0.23"},{"v":13.1113252647994,"d":"13.11"},{"v":3.71274161235569,"d":"3.71"},{"v":0.00040023522509182,"d":"0.00"},{"v":0.0326753836574962,"d":"0.03"},"up","yes"]
[70768,0,"chr16","+",3651837,3658095,"ENST00000246949",9,4200,"ENSG00000213918","DNASE1","GO:0000737(DNA catabolic process, endonucleolytic);GO:0002283(neutrophil activation involved in immune response);GO:0002673(regulation of acute inflammatory response);GO:0003677(DNA binding);GO:0003779(actin binding);GO:0004518(nuclease activity);GO:0004519(endonuclease activity);GO:0004530(deoxyribonuclease I activity);GO:0004536(deoxyribonuclease activity);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0005634(nucleus);GO:0005635(nuclear envelope);GO:0006308(DNA catabolic process);GO:0006915(apoptotic process);GO:0016787(hydrolase activity);GO:0070062(extracellular exosome);GO:0070948(regulation of neutrophil mediated cytotoxicity)","NA","K11994","EC:3.1.21.1","deoxyribonuclease 1 [Source:HGNC Symbol;Acc:HGNC:2956]",{"v":0.214476,"d":"0.21"},{"v":0.231808,"d":"0.23"},{"v":0.007748,"d":"0.01"},0,0,0,"inf","inf",{"v":0.000406554880702512,"d":"0.00"},{"v":0.0331169031747136,"d":"0.03"},"up","yes"]
[22002,0,"chr10","-",73497538,73530831,"ENST00000418501",9,4370,"ENSG00000166348","USP54","GO:0005515(protein binding);GO:0016579(protein deubiquitination);GO:0036459(thiol-dependent ubiquitinyl hydrolase activity)","NA","NA","NA","ubiquitin specific peptidase 54 [Source:HGNC Symbol;Acc:HGNC:23513]",{"v":0.530447,"d":"0.53"},0,{"v":0.424023,"d":"0.42"},0,0,0,"inf","inf",{"v":0.00041170000940113,"d":"0.00"},{"v":0.0333845818499039,"d":"0.03"},"up","yes"]
[3542,0,"chr1","+",28887091,29120041,"ENST00000647103",18,5772,"ENSG00000159023","EPB41","GO:0003779(actin binding);GO:0005198(structural molecule activity);GO:0005200(structural constituent of cytoskeleton);GO:0005515(protein binding);GO:0005516(calmodulin binding);GO:0005545(1-phosphatidylinositol binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005856(cytoskeleton);GO:0005886(plasma membrane);GO:0005938(cell cortex);GO:0007049(cell cycle);GO:0008022(protein C-terminus binding);GO:0008092(cytoskeletal protein binding);GO:0008360(regulation of cell shape);GO:0009898(cytoplasmic side of plasma membrane);GO:0014069(postsynaptic density);GO:0014731(spectrin-associated cytoskeleton);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016323(basolateral plasma membrane);GO:0030036(actin cytoskeleton organization);GO:0030054(cell junction);GO:0030507(spectrin binding);GO:0030863(cortical cytoskeleton);GO:0030866(cortical actin cytoskeleton organization);GO:0031032(actomyosin structure organization);GO:0032092(positive regulation of protein binding);GO:0032991(protein-containing complex);GO:0047485(protein N-terminus binding);GO:0051219(phosphoprotein binding);GO:0051301(cell division);GO:0051924(regulation of calcium ion transport);GO:0065003(protein-containing complex assembly);GO:0099738(cell cortex region);GO:1904478(regulation of intestinal absorption);GO:1904778(positive regulation of protein localization to cell cortex)","NA","NA","NA","erythrocyte membrane protein band 4.1 [Source:HGNC Symbol;Acc:HGNC:3377]",{"v":0.778864,"d":"0.78"},{"v":0.412371,"d":"0.41"},0,{"v":0.002327,"d":"0.00"},0,0,{"v":511.918779544478,"d":"511.92"},{"v":8.99977112179015,"d":"9.00"},{"v":0.000412530991167692,"d":"0.00"},{"v":0.0333845818499039,"d":"0.03"},"up","yes"]
[45265,0,"chr12","+",65278744,65488095,"ENST00000541189",6,528,"ENSG00000174099","MSRB3","GO:0005515(protein binding);GO:0005739(mitochondrion);GO:0005783(endoplasmic reticulum);GO:0005829(cytosol);GO:0006979(response to oxidative stress);GO:0008270(zinc ion binding);GO:0016491(oxidoreductase activity);GO:0016671(oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor);GO:0030091(protein repair);GO:0033743(peptide-methionine (R)-S-oxide reductase activity);GO:0033745(L-methionine-(R)-S-oxide reductase activity);GO:0034599(cellular response to oxidative stress);GO:0046872(metal ion binding);GO:0055114(oxidation-reduction process)","NA","K07305","EC:1.8.4.12","methionine sulfoxide reductase B3 [Source:HGNC Symbol;Acc:HGNC:27375]",{"v":5.987482,"d":"5.99"},{"v":2.235605,"d":"2.24"},0,0,0,0,"inf","inf",{"v":0.000412597777335724,"d":"0.00"},{"v":0.0333845818499039,"d":"0.03"},"up","yes"]
[78752,0,"chr16","+",88706483,88715320,"ENST00000564105",14,1586,"ENSG00000174177","CTU2","GO:0000049(tRNA binding);GO:0002098(tRNA wobble uridine modification);GO:0002143(tRNA wobble position uridine thiolation);GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0006400(tRNA modification);GO:0008033(tRNA processing);GO:0016779(nucleotidyltransferase activity);GO:0016783(sulfurtransferase activity);GO:0032447(protein urmylation);GO:0032991(protein-containing complex);GO:0034227(tRNA thio-modification)","04122(Sulfur relay system)","K14169","NA","cytosolic thiouridylase subunit 2 [Source:HGNC Symbol;Acc:HGNC:28005]",{"v":1.320293,"d":"1.32"},0,{"v":1.271951,"d":"1.27"},0,0,0,"inf","inf",{"v":0.000427549862252923,"d":"0.00"},{"v":0.034517525545886,"d":"0.03"},"up","yes"]
[57872,0,"chr14","-",68874323,68979239,"ENST00000394419",22,3464,"ENSG00000072110","ACTN1","GO:0001725(stress fiber);GO:0001726(ruffle);GO:0002576(platelet degranulation);GO:0003725(double-stranded RNA binding);GO:0003779(actin binding);GO:0005178(integrin binding);GO:0005509(calcium ion binding);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0005615(extracellular space);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005856(cytoskeleton);GO:0005884(actin filament);GO:0005886(plasma membrane);GO:0005903(brush border);GO:0005911(cell-cell junction);GO:0005916(fascia adherens);GO:0005925(focal adhesion);GO:0007015(actin filament organization);GO:0016020(membrane);GO:0017166(vinculin binding);GO:0030017(sarcomere);GO:0030018(Z disc);GO:0030054(cell junction);GO:0030220(platelet formation);GO:0030374(nuclear receptor transcription coactivator activity);GO:0031093(platelet alpha granule lumen);GO:0031143(pseudopodium);GO:0036344(platelet morphogenesis);GO:0042803(protein homodimerization activity);GO:0042981(regulation of apoptotic process);GO:0042995(cell projection);GO:0044325(ion channel binding);GO:0046872(metal ion binding);GO:0048041(focal adhesion assembly);GO:0051015(actin filament binding);GO:0051017(actin filament bundle assembly);GO:0051271(negative regulation of cellular component movement);GO:0051639(actin filament network formation);GO:0051764(actin crosslink formation);GO:0070062(extracellular exosome);GO:0098978(glutamatergic synapse);GO:0099173(postsynapse organization);GO:0099186(structural constituent of postsynapse);GO:1903508(positive regulation of nucleic acid-templated transcription)","04510(Focal adhesion);04520(Adherens junction);04530(Tight junction);04670(Leukocyte transendothelial migration);04810(Regulation of actin cytoskeleton);05146(Amoebiasis);05203(Viral carcinogenesis);05322(Systemic lupus erythematosus)","NA","NA","actinin alpha 1 [Source:HGNC Symbol;Acc:HGNC:163]",{"v":0.071655,"d":"0.07"},{"v":0.393142,"d":"0.39"},{"v":0.504908,"d":"0.50"},{"v":29.365488,"d":"29.37"},0,{"v":69.065216,"d":"69.07"},{"v":0.00985165157408607,"d":"0.01"},{"v":-6.66541868009228,"d":"-6.67"},{"v":0.000431648135163074,"d":"0.00"},{"v":0.0347711236152428,"d":"0.03"},"down","yes"]
[159044,0,"chr5","-",55625858,55712315,"ENST00000508124",15,2370,"ENSG00000177058","SLC38A9","GO:0003333(amino acid transmembrane transport);GO:0005515(protein binding);GO:0005654(nucleoplasm);GO:0005764(lysosome);GO:0005765(lysosomal membrane);GO:0005768(endosome);GO:0005770(late endosome);GO:0006865(amino acid transport);GO:0007050(cell cycle arrest);GO:0015171(amino acid transmembrane transporter activity);GO:0015190(L-leucine transmembrane transporter activity);GO:0015803(branched-chain amino acid transport);GO:0015804(neutral amino acid transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016241(regulation of macroautophagy);GO:0031902(late endosome membrane);GO:0032008(positive regulation of TOR signaling);GO:0043231(intracellular membrane-bounded organelle);GO:0046872(metal ion binding);GO:0061459(L-arginine transmembrane transporter activity);GO:0071230(cellular response to amino acid stimulus);GO:0071986(Ragulator complex);GO:0098655(cation transmembrane transport);GO:1902475(L-alpha-amino acid transmembrane transport);GO:1903400(L-arginine transmembrane transport);GO:1905103(integral component of lysosomal membrane)","04150(mTOR signaling pathway)","K14995","NA","solute carrier family 38 member 9 [Source:HGNC Symbol;Acc:HGNC:26907]",0,{"v":1.199046,"d":"1.20"},{"v":0.574723,"d":"0.57"},0,0,0,"inf","inf",{"v":0.000442213309442635,"d":"0.00"},{"v":0.0355433839204667,"d":"0.04"},"up","yes"]
[174627,0,"chr6","-",143940302,143968838,"ENST00000392307",3,6296,"ENSG00000118495","PLAGL1","GO:0000977(RNA polymerase II regulatory region sequence-specific DNA binding);GO:0000981(DNA-binding transcription factor activity, RNA polymerase II-specific);GO:0001228(DNA-binding transcription activator activity, RNA polymerase II-specific);GO:0003676(nucleic acid binding);GO:0003677(DNA binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005794(Golgi apparatus);GO:0006357(regulation of transcription by RNA polymerase II);GO:0006915(apoptotic process);GO:0006977(DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest);GO:0007050(cell cycle arrest);GO:0016604(nuclear body);GO:0043231(intracellular membrane-bounded organelle);GO:0045944(positive regulation of transcription by RNA polymerase II);GO:0046872(metal ion binding)","NA","K19485","NA","PLAG1 like zinc finger 1 [Source:HGNC Symbol;Acc:HGNC:9046]",0,{"v":0.000292,"d":"0.00"},{"v":0.000186,"d":"0.00"},{"v":0.295981,"d":"0.30"},{"v":0.413789,"d":"0.41"},{"v":0.000131,"d":"0.00"},{"v":0.000673333323942353,"d":"0.00"},{"v":-10.5363915125274,"d":"-10.54"},{"v":0.000470659334318914,"d":"0.00"},{"v":0.0377462552225301,"d":"0.04"},"down","yes"]
[51040,0,"chr13","+",35593006,35672735,"ENST00000379922",13,3794,"ENSG00000172915","NBEA","GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0005802(trans-Golgi network);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0008104(protein localization);GO:0012505(endomembrane system);GO:0016020(membrane);GO:0019901(protein kinase binding)","NA","NA","NA","neurobeachin [Source:HGNC Symbol;Acc:HGNC:7648]",{"v":0.911984,"d":"0.91"},{"v":0.388268,"d":"0.39"},{"v":0.372244,"d":"0.37"},0,0,{"v":0.029384,"d":"0.03"},{"v":56.9185951538252,"d":"56.92"},{"v":5.8308281490634,"d":"5.83"},{"v":0.000477394194578684,"d":"0.00"},{"v":0.0382020508569242,"d":"0.04"},"up","yes"]
[85908,0,"chr17","+",42833471,42843757,"ENST00000293362",11,3144,"ENSG00000131467","PSME3","GO:0000165(MAPK cascade);GO:0000209(protein polyubiquitination);GO:0000502(proteasome complex);GO:0002039(p53 binding);GO:0002223(stimulatory C-type lectin receptor signaling pathway);GO:0002479(antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0006521(regulation of cellular amino acid metabolic process);GO:0006915(apoptotic process);GO:0007049(cell cycle);GO:0008537(proteasome activator complex);GO:0010950(positive regulation of endopeptidase activity);GO:0010972(negative regulation of G2/M transition of mitotic cell cycle);GO:0016020(membrane);GO:0016579(protein deubiquitination);GO:0031145(anaphase-promoting complex-dependent catabolic process);GO:0031146(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process);GO:0033209(tumor necrosis factor-mediated signaling pathway);GO:0038061(NIK/NF-kappaB signaling);GO:0038095(Fc-epsilon receptor signaling pathway);GO:0042802(identical protein binding);GO:0043161(proteasome-mediated ubiquitin-dependent protein catabolic process);GO:0043488(regulation of mRNA stability);GO:0043687(post-translational protein modification);GO:0050852(T cell receptor signaling pathway);GO:0055085(transmembrane transport);GO:0060071(Wnt signaling pathway, planar cell polarity pathway);GO:0061133(endopeptidase activator activity);GO:0061136(regulation of proteasomal protein catabolic process);GO:0061418(regulation of transcription from RNA polymerase II promoter in response to hypoxia);GO:0070498(interleukin-1-mediated signaling pathway);GO:0090090(negative regulation of canonical Wnt signaling pathway);GO:0090263(positive regulation of canonical Wnt signaling pathway);GO:0097371(MDM2/MDM4 family protein binding);GO:1901990(regulation of mitotic cell cycle phase transition);GO:1902036(regulation of hematopoietic stem cell differentiation);GO:2000045(regulation of G1/S transition of mitotic cell cycle);GO:2001237(negative regulation of extrinsic apoptotic signaling pathway)","03050(Proteasome);04612(Antigen processing and presentation);05160(Hepatitis C)","K06698","NA","proteasome activator subunit 3 [Source:HGNC Symbol;Acc:HGNC:9570]",{"v":1.882394,"d":"1.88"},{"v":0.57583,"d":"0.58"},{"v":0.633852,"d":"0.63"},{"v":0.063307,"d":"0.06"},{"v":0.023611,"d":"0.02"},0,{"v":35.5746335626683,"d":"35.57"},{"v":5.15277699120218,"d":"5.15"},{"v":0.000479628801359485,"d":"0.00"},{"v":0.0382965150623958,"d":"0.04"},"up","yes"]
[26977,0,"chr11","-",6476814,6481434,"ENST00000423813",7,1430,"ENSG00000132254","ARFIP2","GO:0001726(ruffle);GO:0005515(protein binding);GO:0005525(GTP binding);GO:0005543(phospholipid binding);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0005938(cell cortex);GO:0006886(intracellular protein transport);GO:0007264(small GTPase mediated signal transduction);GO:0019904(protein domain specific binding);GO:0030032(lamellipodium assembly);GO:0030036(actin cytoskeleton organization);GO:0030742(GTP-dependent protein binding);GO:0031529(ruffle organization);GO:0032588(trans-Golgi network membrane);GO:0042802(identical protein binding);GO:0045296(cadherin binding);GO:0048365(Rac GTPase binding);GO:0070273(phosphatidylinositol-4-phosphate binding)","NA","K20314","NA","ADP ribosylation factor interacting protein 2 [Source:HGNC Symbol;Acc:HGNC:17160]",0,0,0,0,{"v":1.476292,"d":"1.48"},{"v":1.253561,"d":"1.25"},"-inf","-inf",{"v":0.000482338365603353,"d":"0.00"},{"v":0.0384284053122145,"d":"0.04"},"down","yes"]
[177746,0,"chr7","+",30028441,30130483,"ENST00000396259",13,2840,"ENSG00000106086","PLEKHA8","GO:0000139(Golgi membrane);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0005794(Golgi apparatus);GO:0005802(trans-Golgi network);GO:0005829(cytosol);GO:0006661(phosphatidylinositol biosynthetic process);GO:0006869(lipid transport);GO:0008289(lipid binding);GO:0015031(protein transport);GO:0016020(membrane);GO:0017089(glycolipid transporter activity);GO:0035621(ER to Golgi ceramide transport);GO:0035627(ceramide transport);GO:0046836(glycolipid transport);GO:0051861(glycolipid binding);GO:0070273(phosphatidylinositol-4-phosphate binding);GO:0097001(ceramide binding);GO:0120009(intermembrane lipid transfer);GO:0120013(intermembrane lipid transfer activity);GO:1902387(ceramide 1-phosphate binding);GO:1902388(ceramide 1-phosphate transporter activity);GO:1902389(ceramide 1-phosphate transport)","NA","K08051","NA","pleckstrin homology domain containing A8 [Source:HGNC Symbol;Acc:HGNC:30037]",0,{"v":0.833787,"d":"0.83"},{"v":0.568761,"d":"0.57"},0,0,0,"inf","inf",{"v":0.000488091146133854,"d":"0.00"},{"v":0.0388016440679276,"d":"0.04"},"up","yes"]
[171680,0,"chr6","-",69675793,69797010,"ENST00000649934",16,2117,"ENSG00000168216","LMBRD1","GO:0005158(insulin receptor binding);GO:0005764(lysosome);GO:0005765(lysosomal membrane);GO:0005886(plasma membrane);GO:0009235(cobalamin metabolic process);GO:0015420(cobalamin-transporting ATPase activity);GO:0015889(cobalamin transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016032(viral process);GO:0031419(cobalamin binding);GO:0045334(clathrin-coated endocytic vesicle)","04977(Vitamin digestion and absorption)","K14617","NA","LMBR1 domain containing 1 [Source:HGNC Symbol;Acc:HGNC:23038]",{"v":0.013578,"d":"0.01"},{"v":0.061514,"d":"0.06"},{"v":0.017412,"d":"0.02"},{"v":4.812439,"d":"4.81"},{"v":1.588676,"d":"1.59"},{"v":0.01526,"d":"0.02"},{"v":0.0144168631041671,"d":"0.01"},{"v":-6.11609890011806,"d":"-6.12"},{"v":0.000490185809848861,"d":"0.00"},{"v":0.0388507916446616,"d":"0.04"},"down","yes"]
[20587,0,"chr10","-",43556344,43574584,"ENST00000374446",4,2037,"ENSG00000196793","ZNF239","GO:0000122(negative regulation of transcription by RNA polymerase II);GO:0000978(RNA polymerase II proximal promoter sequence-specific DNA binding);GO:0000981(DNA-binding transcription factor activity, RNA polymerase II-specific);GO:0001227(DNA-binding transcription repressor activity, RNA polymerase II-specific);GO:0003676(nucleic acid binding);GO:0003677(DNA binding);GO:0003723(RNA binding);GO:0005515(protein binding);GO:0005634(nucleus);GO:0006357(regulation of transcription by RNA polymerase II);GO:0046872(metal ion binding)","NA","NA","NA","zinc finger protein 239 [Source:HGNC Symbol;Acc:HGNC:13031]",{"v":0.009476,"d":"0.01"},0,{"v":0.002449,"d":"0.00"},{"v":0.857808,"d":"0.86"},{"v":0.016664,"d":"0.02"},{"v":1.216875,"d":"1.22"},{"v":0.00570206665847418,"d":"0.01"},{"v":-7.45429937984992,"d":"-7.45"},{"v":0.000490848152075411,"d":"0.00"},{"v":0.0388507916446616,"d":"0.04"},"down","yes"]
[44845,0,"chr12","+",57693955,57720998,"ENST00000552285",14,2135,"ENSG00000135506","OS9","GO:0000836(Hrd1p ubiquitin ligase complex);GO:0002020(protease binding);GO:0005515(protein binding);GO:0005783(endoplasmic reticulum);GO:0005788(endoplasmic reticulum lumen);GO:0005789(endoplasmic reticulum membrane);GO:0006511(ubiquitin-dependent protein catabolic process);GO:0006605(protein targeting);GO:0006621(protein retention in ER lumen);GO:0016567(protein ubiquitination);GO:0030246(carbohydrate binding);GO:0030433(ubiquitin-dependent ERAD pathway);GO:0030970(retrograde protein transport, ER to cytosol);GO:0034976(response to endoplasmic reticulum stress);GO:0044322(endoplasmic reticulum quality control compartment);GO:0055085(transmembrane transport);GO:1904153(negative regulation of retrograde protein transport, ER to cytosol);GO:1904380(endoplasmic reticulum mannose trimming)","04141(Protein processing in endoplasmic reticulum)","K10088","NA","OS9, endoplasmic reticulum lectin [Source:HGNC Symbol;Acc:HGNC:16994]",{"v":0.338621,"d":"0.34"},{"v":0.943823,"d":"0.94"},{"v":3.088267,"d":"3.09"},{"v":18.086058,"d":"18.09"},{"v":1.084722,"d":"1.08"},{"v":71.086739,"d":"71.09"},{"v":0.048424896323596,"d":"0.05"},{"v":-4.36810722971427,"d":"-4.37"},{"v":0.000493837121640818,"d":"0.00"},{"v":0.0390023970200237,"d":"0.04"},"down","yes"]
[126232,0,"chr20","-",34928806,34955755,"ENST00000643443",13,1437,"ENSG00000100983","GSS","GO:0000166(nucleotide binding);GO:0000287(magnesium ion binding);GO:0004363(glutathione synthase activity);GO:0005515(protein binding);GO:0005524(ATP binding);GO:0005829(cytosol);GO:0006520(cellular amino acid metabolic process);GO:0006750(glutathione biosynthetic process);GO:0006979(response to oxidative stress);GO:0007399(nervous system development);GO:0007568(aging);GO:0009410(response to xenobiotic stimulus);GO:0016594(glycine binding);GO:0016874(ligase activity);GO:0031667(response to nutrient levels);GO:0034612(response to tumor necrosis factor);GO:0042277(peptide binding);GO:0042802(identical protein binding);GO:0042803(protein homodimerization activity);GO:0043200(response to amino acid);GO:0043295(glutathione binding);GO:0046686(response to cadmium ion);GO:0046872(metal ion binding);GO:0070062(extracellular exosome)","00270(Cysteine and methionine metabolism);00480(Glutathione metabolism);04216(Ferroptosis)","K21456","EC:6.3.2.3","glutathione synthetase [Source:HGNC Symbol;Acc:HGNC:4624]",{"v":0.622094,"d":"0.62"},0,{"v":2.305023,"d":"2.31"},0,0,0,"inf","inf",{"v":0.000498420009394479,"d":"0.00"},{"v":0.0392789564887232,"d":"0.04"},"up","yes"]
[96273,0,"chr19","+",572565,583493,"ENST00000333511",9,1977,"ENSG00000172270","BSG","GO:0000139(Golgi membrane);GO:0002080(acrosomal membrane);GO:0005515(protein binding);GO:0005537(mannose binding);GO:0005739(mitochondrion);GO:0005886(plasma membrane);GO:0005887(integral component of plasma membrane);GO:0005925(focal adhesion);GO:0006090(pyruvate metabolic process);GO:0007156(homophilic cell adhesion via plasma membrane adhesion molecules);GO:0007166(cell surface receptor signaling pathway);GO:0007411(axon guidance);GO:0007566(embryo implantation);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0022617(extracellular matrix disassembly);GO:0030198(extracellular matrix organization);GO:0030246(carbohydrate binding);GO:0030424(axon);GO:0042383(sarcolemma);GO:0042470(melanosome);GO:0042475(odontogenesis of dentin-containing tooth);GO:0043231(intracellular membrane-bounded organelle);GO:0043434(response to peptide hormone);GO:0045121(membrane raft);GO:0045296(cadherin binding);GO:0046689(response to mercury ion);GO:0046697(decidualization);GO:0050900(leukocyte migration);GO:0051591(response to cAMP);GO:0070062(extracellular exosome);GO:0070593(dendrite self-avoidance);GO:0072659(protein localization to plasma membrane);GO:0098632(cell-cell adhesion mediator activity)","NA","NA","NA","basigin (Ok blood group) [Source:HGNC Symbol;Acc:HGNC:1116]",{"v":0.91894,"d":"0.92"},{"v":0.639381,"d":"0.64"},{"v":0.878568,"d":"0.88"},{"v":0.581642,"d":"0.58"},{"v":100.304192,"d":"100.30"},{"v":0.826328,"d":"0.83"},{"v":0.023958678609152,"d":"0.02"},{"v":-5.38330784828381,"d":"-5.38"},{"v":0.000501379562248884,"d":"0.00"},{"v":0.0394266655768441,"d":"0.04"},"down","yes"]
[17445,0,"chr1","+",230979094,231000595,"ENST00000366658",5,1170,"ENSG00000173409","ARV1","GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005794(Golgi apparatus);GO:0006629(lipid metabolic process);GO:0006665(sphingolipid metabolic process);GO:0006695(cholesterol biosynthetic process);GO:0006869(lipid transport);GO:0008202(steroid metabolic process);GO:0008203(cholesterol metabolic process);GO:0008206(bile acid metabolic process);GO:0015248(sterol transporter activity);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016125(sterol metabolic process);GO:0030301(cholesterol transport);GO:0032366(intracellular sterol transport);GO:0032383(regulation of intracellular cholesterol transport);GO:0032541(cortical endoplasmic reticulum);GO:0090181(regulation of cholesterol metabolic process);GO:0097036(regulation of plasma membrane sterol distribution)","NA","K21848","NA","ARV1 homolog, fatty acid homeostasis modulator [Source:HGNC Symbol;Acc:HGNC:29561]",0,0,0,{"v":1.136285,"d":"1.14"},0,{"v":1.976972,"d":"1.98"},"-inf","-inf",{"v":0.000513478120684194,"d":"0.00"},{"v":0.0402908426014185,"d":"0.04"},"down","yes"]
[194005,0,"chr8","+",144798876,144809144,"ENST00000359971",5,2335,"ENSG00000197363","ZNF517","GO:0000981(DNA-binding transcription factor activity, RNA polymerase II-specific);GO:0003676(nucleic acid binding);GO:0003677(DNA binding);GO:0005622(intracellular);GO:0005634(nucleus);GO:0006355(regulation of transcription, DNA-templated);GO:0006357(regulation of transcription by RNA polymerase II);GO:0046872(metal ion binding)","05168(Herpes simplex virus 1 infection)","K09228","NA","zinc finger protein 517 [Source:HGNC Symbol;Acc:HGNC:27984]",0,0,0,{"v":1.047311,"d":"1.05"},{"v":0.590546,"d":"0.59"},0,"-inf","-inf",{"v":0.000516786004104245,"d":"0.00"},{"v":0.0404630076058346,"d":"0.04"},"down","yes"]
[179800,0,"chr7","-",72948298,72954720,"ENST00000485741",12,1647,"ENSG00000106133","NSUN5P2","NA","NA","NA","NA","NOP2/Sun RNA methyltransferase family member 5 pseudogene 2 [Source:HGNC Symbol;Acc:HGNC:16609]",0,0,0,{"v":1.099924,"d":"1.10"},{"v":1.164716,"d":"1.16"},0,"-inf","-inf",{"v":0.000519064290286753,"d":"0.00"},{"v":0.040467701748991,"d":"0.04"},"down","yes"]
[44247,0,"chr12","-",56202175,56221921,"ENST00000345093",7,5596,"ENSG00000181852","RNF41","GO:0000209(protein polyubiquitination);GO:0004842(ubiquitin-protein transferase activity);GO:0005128(erythropoietin receptor binding);GO:0005135(interleukin-3 receptor binding);GO:0005515(protein binding);GO:0005829(cytosol);GO:0006914(autophagy);GO:0006915(apoptotic process);GO:0008270(zinc ion binding);GO:0008285(negative regulation of cell population proliferation);GO:0010468(regulation of gene expression);GO:0010498(proteasomal protein catabolic process);GO:0016567(protein ubiquitination);GO:0016740(transferase activity);GO:0017160(Ral GTPase binding);GO:0019904(protein domain specific binding);GO:0030336(negative regulation of cell migration);GO:0030971(receptor tyrosine kinase binding);GO:0043408(regulation of MAPK cascade);GO:0045619(regulation of lymphocyte differentiation);GO:0045637(regulation of myeloid cell differentiation);GO:0045732(positive regulation of protein catabolic process);GO:0046872(metal ion binding);GO:0048471(perinuclear region of cytoplasm);GO:0051091(positive regulation of DNA-binding transcription factor activity);GO:0051865(protein autoubiquitination);GO:0051896(regulation of protein kinase B signaling);GO:0061630(ubiquitin protein ligase activity);GO:0071782(endoplasmic reticulum tubular network);GO:0097191(extrinsic apoptotic signaling pathway);GO:1901525(negative regulation of mitophagy);GO:2000114(regulation of establishment of cell polarity);GO:2000377(regulation of reactive oxygen species metabolic process);GO:2000379(positive regulation of reactive oxygen species metabolic process)","04144(Endocytosis)","K11981","EC:2.3.2.27","ring finger protein 41 [Source:HGNC Symbol;Acc:HGNC:18401]",{"v":0.573639,"d":"0.57"},{"v":1.232507,"d":"1.23"},{"v":0.380672,"d":"0.38"},{"v":1.369339,"d":"1.37"},{"v":9.910585,"d":"9.91"},{"v":9.962765,"d":"9.96"},{"v":0.102944500105425,"d":"0.10"},{"v":-3.28006134002729,"d":"-3.28"},{"v":0.000519073741123859,"d":"0.00"},{"v":0.040467701748991,"d":"0.04"},"down","yes"]
[41714,0,"chr12","+",41509551,41574590,"ENST00000548316",6,2971,"ENSG00000165966","PDZRN4","GO:0005515(protein binding);GO:0016567(protein ubiquitination);GO:0046872(metal ion binding);GO:0061630(ubiquitin protein ligase activity)","NA","K15682","EC:2.3.2.27","PDZ domain containing ring finger 4 [Source:HGNC Symbol;Acc:HGNC:30552]",{"v":0.426346,"d":"0.43"},{"v":0.897065,"d":"0.90"},0,0,0,0,"inf","inf",{"v":0.000520519808006086,"d":"0.00"},{"v":0.0404722380385384,"d":"0.04"},"up","yes"]
[188333,0,"chr8","-",37858949,37899454,"ENST00000330843",6,7811,"ENSG00000156675","RAB11FIP1","GO:0005768(endosome);GO:0005829(cytosol);GO:0015031(protein transport);GO:0016020(membrane);GO:0017137(Rab GTPase binding);GO:0030670(phagocytic vesicle membrane);GO:0031410(cytoplasmic vesicle);GO:0043231(intracellular membrane-bounded organelle);GO:0045055(regulated exocytosis);GO:0055037(recycling endosome);GO:0070164(negative regulation of adiponectin secretion)","04144(Endocytosis)","K12484","NA","RAB11 family interacting protein 1 [Source:HGNC Symbol;Acc:HGNC:30265]",{"v":0.068398,"d":"0.07"},{"v":0.174224,"d":"0.17"},{"v":0.221947,"d":"0.22"},{"v":0.811107,"d":"0.81"},{"v":2.556136,"d":"2.56"},{"v":2.340754,"d":"2.34"},{"v":0.0813891457896702,"d":"0.08"},{"v":-3.61901978299263,"d":"-3.62"},{"v":0.000521359961520396,"d":"0.00"},{"v":0.0404722380385384,"d":"0.04"},"down","yes"]
[6241,0,"chr1","-",52352538,52360196,"ENST00000438021",19,2521,"ENSG00000154222","CC2D1B","GO:0000122(negative regulation of transcription by RNA polymerase II);GO:0000978(RNA polymerase II proximal promoter sequence-specific DNA binding);GO:0001227(DNA-binding transcription repressor activity, RNA polymerase II-specific);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0043231(intracellular membrane-bounded organelle)","NA","K18260","NA","coiled-coil and C2 domain containing 1B [Source:HGNC Symbol;Acc:HGNC:29386]",0,{"v":0.971267,"d":"0.97"},{"v":0.564436,"d":"0.56"},0,0,0,"inf","inf",{"v":0.000522802201292133,"d":"0.00"},{"v":0.040497663055316,"d":"0.04"},"up","yes"]
[96868,0,"chr19","-",2037465,2050887,"ENST00000591601",13,3582,"ENSG00000099875","MKNK2","GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0004683(calmodulin-dependent protein kinase activity);GO:0005515(protein binding);GO:0005516(calmodulin binding);GO:0005524(ATP binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0006417(regulation of translation);GO:0006468(protein phosphorylation);GO:0006915(apoptotic process);GO:0007166(cell surface receptor signaling pathway);GO:0009931(calcium-dependent protein serine/threonine kinase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0016604(nuclear body);GO:0016605(PML body);GO:0016740(transferase activity);GO:0018105(peptidyl-serine phosphorylation);GO:0030097(hemopoiesis);GO:0035556(intracellular signal transduction);GO:0046777(protein autophosphorylation);GO:0046872(metal ion binding);GO:0071243(cellular response to arsenic-containing substance);GO:0097192(extrinsic apoptotic signaling pathway in absence of ligand)","04010(MAPK signaling pathway);04066(HIF-1 signaling pathway);04910(Insulin signaling pathway)","K04372","EC:2.7.11.1","MAP kinase interacting serine/threonine kinase 2 [Source:HGNC Symbol;Acc:HGNC:7111]",{"v":0.038721,"d":"0.04"},{"v":0.065967,"d":"0.07"},{"v":0.020165,"d":"0.02"},{"v":1.968152,"d":"1.97"},{"v":0.035457,"d":"0.04"},{"v":2.662291,"d":"2.66"},{"v":0.0267586103431278,"d":"0.03"},{"v":-5.22385299543721,"d":"-5.22"},{"v":0.000552225676283424,"d":"0.00"},{"v":0.0426858698284612,"d":"0.04"},"down","yes"]
[31274,0,"chr11","-",62433547,62517357,"ENST00000525875",3,793,"ENSG00000124942","AHNAK","GO:0003723(RNA binding);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005765(lysosomal membrane);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0005925(focal adhesion);GO:0015629(actin cytoskeleton);GO:0016020(membrane);GO:0030315(T-tubule);GO:0031982(vesicle);GO:0042383(sarcolemma);GO:0043034(costamere);GO:0043484(regulation of RNA splicing);GO:0044291(cell-cell contact zone);GO:0044548(S100 protein binding);GO:0045121(membrane raft);GO:0045296(cadherin binding);GO:0051259(protein complex oligomerization);GO:0070062(extracellular exosome);GO:0097493(structural molecule activity conferring elasticity);GO:1901385(regulation of voltage-gated calcium channel activity)","NA","NA","NA","AHNAK nucleoprotein [Source:HGNC Symbol;Acc:HGNC:347]",0,0,{"v":0.239036,"d":"0.24"},0,{"v":47.66996,"d":"47.67"},{"v":50.93784,"d":"50.94"},{"v":0.00242410843766923,"d":"0.00"},{"v":-8.68833004831471,"d":"-8.69"},{"v":0.000558691588959973,"d":"0.00"},{"v":0.0430939817981228,"d":"0.04"},"down","yes"]
[1851,0,"chr1","+",15152566,15220339,"ENST00000376014",4,1843,"ENSG00000171729","TMEM51","GO:0003674(molecular_function);GO:0005515(protein binding);GO:0005575(cellular_component);GO:0008150(biological_process);GO:0016020(membrane);GO:0016021(integral component of membrane)","NA","NA","NA","transmembrane protein 51 [Source:HGNC Symbol;Acc:HGNC:25488]",{"v":0.908745,"d":"0.91"},{"v":1.082234,"d":"1.08"},0,0,0,0,"inf","inf",{"v":0.000562482570461241,"d":"0.00"},{"v":0.0432359580580755,"d":"0.04"},"up","yes"]
[25619,0,"chr11","+",313527,315240,"ENST00000328221",3,844,"ENSG00000185885","IFITM1","GO:0001503(ossification);GO:0002376(immune system process);GO:0005515(protein binding);GO:0005886(plasma membrane);GO:0007166(cell surface receptor signaling pathway);GO:0008285(negative regulation of cell population proliferation);GO:0009615(response to virus);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0030336(negative regulation of cell migration);GO:0032991(protein-containing complex);GO:0034341(response to interferon-gamma);GO:0035455(response to interferon-alpha);GO:0035456(response to interferon-beta);GO:0045071(negative regulation of viral genome replication);GO:0045087(innate immune response);GO:0045669(positive regulation of osteoblast differentiation);GO:0046597(negative regulation of viral entry into host cell);GO:0050776(regulation of immune response);GO:0051607(defense response to virus);GO:0060337(type I interferon signaling pathway)","04662(B cell receptor signaling pathway)","K19831","NA","interferon induced transmembrane protein 1 [Source:HGNC Symbol;Acc:HGNC:5412]",{"v":2.69115,"d":"2.69"},{"v":221.092148,"d":"221.09"},{"v":2.6452,"d":"2.65"},{"v":1.722656,"d":"1.72"},{"v":1.771474,"d":"1.77"},{"v":3.443857,"d":"3.44"},{"v":32.6360510620732,"d":"32.64"},{"v":5.02839459772915,"d":"5.03"},{"v":0.000562912418427463,"d":"0.00"},{"v":0.0432359580580755,"d":"0.04"},"up","yes"]
[149370,0,"chr4","+",2907377,2930076,"ENST00000513762",6,3581,"ENSG00000087274","ADD1","GO:0000902(cell morphogenesis);GO:0001701(in utero embryonic development);GO:0003723(RNA binding);GO:0003779(actin binding);GO:0005198(structural molecule activity);GO:0005516(calmodulin binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005856(cytoskeleton);GO:0005886(plasma membrane);GO:0005913(cell-cell adherens junction);GO:0005925(focal adhesion);GO:0006884(cell volume homeostasis);GO:0008134(transcription factor binding);GO:0008290(F-actin capping protein complex);GO:0014069(postsynaptic density);GO:0016020(membrane);GO:0016604(nuclear body);GO:0020027(hemoglobin metabolic process);GO:0030036(actin cytoskeleton organization);GO:0030218(erythrocyte differentiation);GO:0030507(spectrin binding);GO:0032092(positive regulation of protein binding);GO:0035264(multicellular organism growth);GO:0036498(IRE1-mediated unfolded protein response);GO:0042803(protein homodimerization activity);GO:0044853(plasma membrane raft);GO:0045296(cadherin binding);GO:0046982(protein heterodimerization activity);GO:0048873(homeostasis of number of cells within a tissue);GO:0051015(actin filament binding);GO:0051016(barbed-end actin filament capping);GO:0051017(actin filament bundle assembly);GO:0055085(transmembrane transport);GO:0071277(cellular response to calcium ion);GO:1903142(positive regulation of establishment of endothelial barrier);GO:1903393(positive regulation of adherens junction organization)","NA","NA","NA","adducin 1 [Source:HGNC Symbol;Acc:HGNC:243]",{"v":0.220642,"d":"0.22"},{"v":0.185088,"d":"0.19"},{"v":0.18189,"d":"0.18"},{"v":0.216106,"d":"0.22"},{"v":9.134585,"d":"9.13"},{"v":3.149343,"d":"3.15"},{"v":0.0470094721342358,"d":"0.05"},{"v":-4.4109047090643,"d":"-4.41"},{"v":0.000565686773702742,"d":"0.00"},{"v":0.0433573849970899,"d":"0.04"},"down","yes"]
[102878,0,"chr19","+",36115519,36125778,"ENST00000589996",6,724,"ENSG00000105254","TBCB","GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005856(cytoskeleton);GO:0005874(microtubule);GO:0007275(multicellular organism development);GO:0007399(nervous system development);GO:0015630(microtubule cytoskeleton);GO:0030154(cell differentiation)","NA","NA","NA","tubulin folding cofactor B [Source:HGNC Symbol;Acc:HGNC:1989]",{"v":3.898023,"d":"3.90"},0,{"v":1.41175,"d":"1.41"},0,0,0,"inf","inf",{"v":0.000569432532356059,"d":"0.00"},{"v":0.0435525976852539,"d":"0.04"},"up","yes"]
[83986,0,"chr17","-",31851871,31859291,"ENST00000496655",5,1062,"ENSG00000172301","COPRS","GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0006325(chromatin organization);GO:0007517(muscle organ development);GO:0042393(histone binding);GO:0043985(histone H4-R3 methylation)","NA","NA","NA","coordinator of PRMT5 and differentiation stimulator [Source:HGNC Symbol;Acc:HGNC:28848]",{"v":0.512507,"d":"0.51"},{"v":0.588045,"d":"0.59"},{"v":0.66529,"d":"0.67"},{"v":18.301792,"d":"18.30"},{"v":17.037548,"d":"17.04"},{"v":0.66636,"d":"0.67"},{"v":0.0490434014614353,"d":"0.05"},{"v":-4.34979714750448,"d":"-4.35"},{"v":0.000571761735002863,"d":"0.00"},{"v":0.0436388735980126,"d":"0.04"},"down","yes"]
[86554,0,"chr17","+",45135690,45144176,"ENST00000592162",9,1684,"ENSG00000181513","ACBD4","GO:0000062(fatty-acyl-CoA binding);GO:0005515(protein binding);GO:0008289(lipid binding);GO:0016020(membrane);GO:0016021(integral component of membrane)","NA","NA","NA","acyl-CoA binding domain containing 4 [Source:HGNC Symbol;Acc:HGNC:23337]",0,0,0,{"v":1.343347,"d":"1.34"},{"v":0.79915,"d":"0.80"},0,"-inf","-inf",{"v":0.000575564194210734,"d":"0.00"},{"v":0.0438369961754213,"d":"0.04"},"down","yes"]
[26553,0,"chr11","+",3808042,3826314,"ENST00000493547",7,1772,"ENSG00000148985","PGAP2","GO:0000139(Golgi membrane);GO:0005515(protein binding);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005794(Golgi apparatus);GO:0006506(GPI anchor biosynthetic process);GO:0008565(protein transporter activity);GO:0015031(protein transport);GO:0016020(membrane);GO:0016021(integral component of membrane)","NA","NA","NA","post-GPI attachment to proteins 2 [Source:HGNC Symbol;Acc:HGNC:17893]",{"v":0.071159,"d":"0.07"},{"v":3.864673,"d":"3.86"},{"v":4.002593,"d":"4.00"},{"v":0.045572,"d":"0.05"},{"v":0.108859,"d":"0.11"},{"v":0.00195,"d":"0.00"},{"v":50.7633599989769,"d":"50.76"},{"v":5.66571565842085,"d":"5.67"},{"v":0.000592575972881895,"d":"0.00"},{"v":0.0450382533364001,"d":"0.05"},"up","yes"]
[179010,0,"chr7","-",50590079,50726992,"ENST00000403097",18,4895,"ENSG00000106070","GRB10","GO:0005070(SH3/SH2 adaptor activity);GO:0005158(insulin receptor binding);GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0007165(signal transduction);GO:0007411(axon guidance);GO:0009967(positive regulation of signal transduction);GO:0030178(negative regulation of Wnt signaling pathway);GO:0030949(positive regulation of vascular endothelial growth factor receptor signaling pathway);GO:0032991(protein-containing complex);GO:0042326(negative regulation of phosphorylation);GO:0046325(negative regulation of glucose import);GO:0046627(negative regulation of insulin receptor signaling pathway);GO:0048009(insulin-like growth factor receptor signaling pathway);GO:0120162(positive regulation of cold-induced thermogenesis)","04150(mTOR signaling pathway)","K20064","NA","growth factor receptor bound protein 10 [Source:HGNC Symbol;Acc:HGNC:4564]",{"v":0.001792,"d":"0.00"},{"v":4.6696,"d":"4.67"},{"v":2.180812,"d":"2.18"},0,0,{"v":0.027216,"d":"0.03"},{"v":251.771164021164,"d":"251.77"},{"v":7.97596924683508,"d":"7.98"},{"v":0.000599479771740461,"d":"0.00"},{"v":0.045373399563308,"d":"0.05"},"up","yes"]
[17038,0,"chr1","+",226063977,226072001,"ENST00000366813",3,1308,"ENSG00000163041","H3F3A","GO:0000183(chromatin silencing at rDNA);GO:0000228(nuclear chromosome);GO:0000784(nuclear chromosome, telomeric region);GO:0000786(nucleosome);GO:0000788(nuclear nucleosome);GO:0000979(RNA polymerase II core promoter sequence-specific DNA binding);GO:0000980(RNA polymerase II distal enhancer sequence-specific DNA binding);GO:0001649(osteoblast differentiation);GO:0001740(Barr body);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005694(chromosome);GO:0006334(nucleosome assembly);GO:0006336(DNA replication-independent nucleosome assembly);GO:0006997(nucleus organization);GO:0007283(spermatogenesis);GO:0007286(spermatid development);GO:0007338(single fertilization);GO:0007566(embryo implantation);GO:0007596(blood coagulation);GO:0008283(cell population proliferation);GO:0008584(male gonad development);GO:0030307(positive regulation of cell growth);GO:0031492(nucleosomal DNA binding);GO:0031508(pericentric heterochromatin assembly);GO:0031509(telomeric heterochromatin assembly);GO:0032200(telomere organization);GO:0032991(protein-containing complex);GO:0035264(multicellular organism growth);GO:0042692(muscle cell differentiation);GO:0044267(cellular protein metabolic process);GO:0045652(regulation of megakaryocyte differentiation);GO:0045814(negative regulation of gene expression, epigenetic);GO:0046982(protein heterodimerization activity);GO:0048477(oogenesis);GO:0060964(regulation of gene silencing by miRNA);GO:0070062(extracellular exosome);GO:0090230(regulation of centromere complex assembly);GO:1902340(negative regulation of chromosome condensation)","05034(Alcoholism);05202(Transcriptional misregulation in cancer);05322(Systemic lupus erythematosus)","K11253","NA","H3 histone family member 3A [Source:HGNC Symbol;Acc:HGNC:4764]",{"v":0.446779,"d":"0.45"},{"v":8.949634,"d":"8.95"},{"v":14.356094,"d":"14.36"},{"v":0.249708,"d":"0.25"},{"v":0.403035,"d":"0.40"},{"v":0.371644,"d":"0.37"},{"v":23.1870445446887,"d":"23.19"},{"v":4.53524703852604,"d":"4.54"},{"v":0.000599483396377314,"d":"0.00"},{"v":0.045373399563308,"d":"0.05"},"up","yes"]
[22820,0,"chr10","+",87504875,87553388,"ENST00000371994",3,2183,"ENSG00000107789","MINPP1","GO:0001503(ossification);GO:0003993(acid phosphatase activity);GO:0004446(inositol-hexakisphosphate phosphatase activity);GO:0005783(endoplasmic reticulum);GO:0005788(endoplasmic reticulum lumen);GO:0006470(protein dephosphorylation);GO:0006797(polyphosphate metabolic process);GO:0016311(dephosphorylation);GO:0016787(hydrolase activity);GO:0016791(phosphatase activity);GO:0030282(bone mineralization);GO:0030351(inositol-1,3,4,5,6-pentakisphosphate 3-phosphatase activity);GO:0034417(bisphosphoglycerate 3-phosphatase activity);GO:0043647(inositol phosphate metabolic process);GO:0051717(inositol-1,3,4,5-tetrakisphosphate 3-phosphatase activity);GO:0052745(inositol phosphate phosphatase activity);GO:0052826(inositol hexakisphosphate 2-phosphatase activity);GO:0070062(extracellular exosome);GO:0101006(protein histidine phosphatase activity)","00010(Glycolysis / Gluconeogenesis);00562(Inositol phosphate metabolism)","K03103","3.1.3.80;EC:3.1.3.62","multiple inositol-polyphosphate phosphatase 1 [Source:HGNC Symbol;Acc:HGNC:7102]",{"v":0.010609,"d":"0.01"},{"v":0.004099,"d":"0.00"},{"v":0.004184,"d":"0.00"},{"v":0.201782,"d":"0.20"},{"v":0.424188,"d":"0.42"},{"v":0.698796,"d":"0.70"},{"v":0.0142606316889171,"d":"0.01"},{"v":-6.13181830096041,"d":"-6.13"},{"v":0.000600749771117625,"d":"0.00"},{"v":0.0453747176397158,"d":"0.05"},"down","yes"]
[18337,0,"chr1","-",247298201,247329245,"ENST00000461277",8,3857,"ENSG00000162714","ZNF496","GO:0000981(DNA-binding transcription factor activity, RNA polymerase II-specific);GO:0003676(nucleic acid binding);GO:0003677(DNA binding);GO:0003700(DNA-binding transcription factor activity);GO:0005515(protein binding);GO:0005622(intracellular);GO:0005634(nucleus);GO:0006355(regulation of transcription, DNA-templated);GO:0006357(regulation of transcription by RNA polymerase II);GO:0045893(positive regulation of transcription, DNA-templated);GO:0046872(metal ion binding)","NA","K09229","NA","zinc finger protein 496 [Source:HGNC Symbol;Acc:HGNC:23713]",{"v":0.379464,"d":"0.38"},0,{"v":10.998426,"d":"11.00"},{"v":0.018818,"d":"0.02"},0,{"v":0.017135,"d":"0.02"},{"v":316.465663505132,"d":"316.47"},{"v":8.3059051656427,"d":"8.31"},{"v":0.000611235681338708,"d":"0.00"},{"v":0.0460709383880399,"d":"0.05"},"up","yes"]
[47780,0,"chr12","+",109574830,109597263,"ENST00000636996",9,1725,"ENSG00000110921","MVK","GO:0000166(nucleotide binding);GO:0000287(magnesium ion binding);GO:0004496(mevalonate kinase activity);GO:0005515(protein binding);GO:0005524(ATP binding);GO:0005737(cytoplasm);GO:0005777(peroxisome);GO:0005829(cytosol);GO:0006629(lipid metabolic process);GO:0006694(steroid biosynthetic process);GO:0006695(cholesterol biosynthetic process);GO:0008202(steroid metabolic process);GO:0008203(cholesterol metabolic process);GO:0008299(isoprenoid biosynthetic process);GO:0016126(sterol biosynthetic process);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0016740(transferase activity);GO:0019287(isopentenyl diphosphate biosynthetic process, mevalonate pathway);GO:0042802(identical protein binding);GO:0045540(regulation of cholesterol biosynthetic process);GO:0046872(metal ion binding);GO:0050728(negative regulation of inflammatory response)","00900(Terpenoid backbone biosynthesis);04146(Peroxisome)","K00869","EC:2.7.1.36","mevalonate kinase [Source:HGNC Symbol;Acc:HGNC:7530]",0,0,0,0,{"v":1.279761,"d":"1.28"},{"v":0.77686,"d":"0.78"},"-inf","-inf",{"v":0.000617532161797288,"d":"0.00"},{"v":0.0464491582569264,"d":"0.05"},"down","yes"]
[116724,0,"chr2","+",119367081,119372454,"ENST00000460901",4,774,"ENSG00000155368","DBI","GO:0000062(fatty-acyl-CoA binding);GO:0005783(endoplasmic reticulum);GO:0005788(endoplasmic reticulum lumen);GO:0005794(Golgi apparatus);GO:0006637(acyl-CoA metabolic process);GO:0008289(lipid binding);GO:0030156(benzodiazepine receptor binding);GO:0036042(long-chain fatty acyl-CoA binding);GO:0036151(phosphatidylcholine acyl-chain remodeling);GO:0046983(protein dimerization activity);GO:0070062(extracellular exosome)","03320(PPAR signaling pathway)","NA","NA","diazepam binding inhibitor, acyl-CoA binding protein [Source:HGNC Symbol;Acc:HGNC:2690]",0,0,0,{"v":2.195648,"d":"2.20"},{"v":2.273171,"d":"2.27"},0,"-inf","-inf",{"v":0.000623031319222238,"d":"0.00"},{"v":0.0466872131387624,"d":"0.05"},"down","yes"]
[141108,0,"chr3","+",57556276,57560937,"ENST00000487257",2,3040,"ENSG00000174840","PDE12","GO:0000175(3'-5'-exoribonuclease activity);GO:0000288(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay);GO:0000958(mitochondrial mRNA catabolic process);GO:0004518(nuclease activity);GO:0004527(exonuclease activity);GO:0004535(poly(A)-specific ribonuclease activity);GO:0005739(mitochondrion);GO:0005759(mitochondrial matrix);GO:0005829(cytosol);GO:0006397(mRNA processing);GO:0016787(hydrolase activity);GO:0034611(oligoribonucleotidase activity);GO:0035457(cellular response to interferon-alpha);GO:0044528(regulation of mitochondrial mRNA stability);GO:0045070(positive regulation of viral genome replication);GO:0046872(metal ion binding);GO:0051607(defense response to virus);GO:0060548(negative regulation of cell death);GO:0071346(cellular response to interferon-gamma);GO:0071359(cellular response to dsRNA);GO:0090305(nucleic acid phosphodiester bond hydrolysis);GO:0090324(negative regulation of oxidative phosphorylation);GO:0090503(RNA phosphodiester bond hydrolysis, exonucleolytic)","NA","K19612","3.1.4.-;EC:3.1.13.4","phosphodiesterase 12 [Source:HGNC Symbol;Acc:HGNC:25386]",{"v":0.04285,"d":"0.04"},{"v":0.293652,"d":"0.29"},{"v":1.137196,"d":"1.14"},{"v":0.013204,"d":"0.01"},{"v":0.001798,"d":"0.00"},{"v":0.002754,"d":"0.00"},{"v":82.9971840504618,"d":"83.00"},{"v":6.37499048405354,"d":"6.37"},{"v":0.000623267227423611,"d":"0.00"},{"v":0.0466872131387624,"d":"0.05"},"up","yes"]
[14046,0,"chr1","-",172441457,172444086,"ENST00000367728",1,2630,"ENSG00000135845","PIGC","GO:0000506(glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex);GO:0003824(catalytic activity);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0006506(GPI anchor biosynthetic process);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016254(preassembly of GPI anchor in ER membrane);GO:0016740(transferase activity);GO:0016757(transferase activity, transferring glycosyl groups);GO:0017176(phosphatidylinositol N-acetylglucosaminyltransferase activity)","00563(Glycosylphosphatidylinositol (GPI)-anchor biosynthesis)","K03859","NA","phosphatidylinositol glycan anchor biosynthesis class C [Source:HGNC Symbol;Acc:HGNC:8960]",{"v":0.057919,"d":"0.06"},{"v":0.022566,"d":"0.02"},{"v":0.066439,"d":"0.07"},{"v":0.167493,"d":"0.17"},{"v":1.599322,"d":"1.60"},{"v":1.343231,"d":"1.34"},{"v":0.0472417449774055,"d":"0.05"},{"v":-4.40379393495171,"d":"-4.40"},{"v":0.000628369226619865,"d":"0.00"},{"v":0.0469725391010282,"d":"0.05"},"down","yes"]
[14230,0,"chr1","-",175158953,175192754,"ENST00000545251",3,2485,"ENSG00000235750","KIAA0040","GO:0005515(protein binding);GO:0016020(membrane);GO:0016021(integral component of membrane)","NA","NA","NA","KIAA0040 [Source:HGNC Symbol;Acc:HGNC:28950]",0,0,0,{"v":0.733695,"d":"0.73"},0,{"v":0.589135,"d":"0.59"},"-inf","-inf",{"v":0.000630307761873431,"d":"0.00"},{"v":0.0470207001824676,"d":"0.05"},"down","yes"]
[143397,0,"chr3","-",121769994,121835079,"ENST00000393650",14,2253,"ENSG00000173226","IQCB1","GO:0001750(photoreceptor outer segment);GO:0005515(protein binding);GO:0005516(calmodulin binding);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0005813(centrosome);GO:0005814(centriole);GO:0005815(microtubule organizing center);GO:0005829(cytosol);GO:0005856(cytoskeleton);GO:0015630(microtubule cytoskeleton);GO:0019899(enzyme binding);GO:0030030(cell projection organization);GO:0032391(photoreceptor connecting cilium);GO:0045171(intercellular bridge);GO:0045494(photoreceptor cell maintenance);GO:0048496(maintenance of animal organ identity);GO:0060271(cilium assembly);GO:0070062(extracellular exosome);GO:0072686(mitotic spindle);GO:0097711(ciliary basal body-plasma membrane docking)","NA","K16774","NA","IQ motif containing B1 [Source:HGNC Symbol;Acc:HGNC:28949]",0,{"v":0.007455,"d":"0.01"},0,{"v":0.483011,"d":"0.48"},{"v":0.843805,"d":"0.84"},{"v":0.051902,"d":"0.05"},{"v":0.00540719712080353,"d":"0.01"},{"v":-7.53090333345357,"d":"-7.53"},{"v":0.000634870171484364,"d":"0.00"},{"v":0.047264002725465,"d":"0.05"},"down","yes"]
[139828,0,"chr3","-",49108046,49117978,"ENST00000398896",24,3907,"ENSG00000172046","USP19","GO:0004843(thiol-dependent ubiquitin-specific protease activity);GO:0005515(protein binding);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005829(cytosol);GO:0006508(proteolysis);GO:0006511(ubiquitin-dependent protein catabolic process);GO:0008233(peptidase activity);GO:0008234(cysteine-type peptidase activity);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016579(protein deubiquitination);GO:0016787(hydrolase activity);GO:0030433(ubiquitin-dependent ERAD pathway);GO:0031625(ubiquitin protein ligase binding);GO:0031647(regulation of protein stability);GO:0034976(response to endoplasmic reticulum stress);GO:0036459(thiol-dependent ubiquitinyl hydrolase activity);GO:0046872(metal ion binding);GO:0048642(negative regulation of skeletal muscle tissue development);GO:0050821(protein stabilization);GO:0051879(Hsp90 protein binding);GO:0071108(protein K48-linked deubiquitination);GO:0090068(positive regulation of cell cycle process);GO:1900037(regulation of cellular response to hypoxia);GO:1901799(negative regulation of proteasomal protein catabolic process);GO:1904292(regulation of ERAD pathway);GO:1990380(Lys48-specific deubiquitinase activity)","NA","K11847","EC:3.4.19.12","ubiquitin specific peptidase 19 [Source:HGNC Symbol;Acc:HGNC:12617]",{"v":0.044571,"d":"0.04"},{"v":0.098126,"d":"0.10"},{"v":0.00312,"d":"0.00"},{"v":6.309401,"d":"6.31"},{"v":0.209904,"d":"0.21"},{"v":0.289701,"d":"0.29"},{"v":0.021415313777077,"d":"0.02"},{"v":-5.54521337402994,"d":"-5.55"},{"v":0.000637540349700943,"d":"0.00"},{"v":0.0472808352395785,"d":"0.05"},"down","yes"]
[92215,0,"chr17","+",82458726,82488065,"ENST00000582907",12,1454,"ENSG00000141562","NARF","GO:0005521(lamin binding);GO:0005634(nucleus);GO:0005638(lamin filament);GO:0005652(nuclear lamina);GO:0005730(nucleolus);GO:0031981(nuclear lumen)","NA","NA","NA","nuclear prelamin A recognition factor [Source:HGNC Symbol;Acc:HGNC:29916]",0,{"v":9.749284,"d":"9.75"},{"v":7.219814,"d":"7.22"},0,{"v":0.015362,"d":"0.02"},{"v":0.070925,"d":"0.07"},{"v":196.6588014417,"d":"196.66"},{"v":7.61955094514858,"d":"7.62"},{"v":0.000637699126545374,"d":"0.00"},{"v":0.0472808352395785,"d":"0.05"},"up","yes"]
[200687,0,"chr9","+",136807948,136841187,"ENST00000311502",15,3104,"ENSG00000196642","RABL6","GO:0000166(nucleotide binding);GO:0005515(protein binding);GO:0005525(GTP binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005813(centrosome);GO:0005829(cytosol)","NA","NA","NA","RAB, member RAS oncogene family like 6 [Source:HGNC Symbol;Acc:HGNC:24703]",{"v":1.457455,"d":"1.46"},{"v":1.933829,"d":"1.93"},{"v":1.482962,"d":"1.48"},{"v":19.816669,"d":"19.82"},{"v":2.057877,"d":"2.06"},{"v":20.795027,"d":"20.80"},{"v":0.114232359437954,"d":"0.11"},{"v":-3.12995670348902,"d":"-3.13"},{"v":0.000651024392657962,"d":"0.00"},{"v":0.0481705013956492,"d":"0.05"},"down","yes"]
[136115,0,"chr3","+",196763,409417,"ENST00000256509",28,7856,"ENSG00000134121","CHL1","GO:0001764(neuron migration);GO:0002020(protease binding);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0005886(plasma membrane);GO:0007155(cell adhesion);GO:0007165(signal transduction);GO:0007275(multicellular organism development);GO:0007399(nervous system development);GO:0007411(axon guidance);GO:0008344(adult locomotory behavior);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0030154(cell differentiation);GO:0030425(dendrite);GO:0031175(neuron projection development);GO:0035640(exploration behavior);GO:0043524(negative regulation of neuron apoptotic process);GO:0045177(apical part of cell);GO:0050890(cognition);GO:0070062(extracellular exosome)","NA","K06758","NA","cell adhesion molecule L1 like [Source:HGNC Symbol;Acc:HGNC:1939]",{"v":0.060726,"d":"0.06"},{"v":0.017919,"d":"0.02"},{"v":0.016559,"d":"0.02"},{"v":0.502448,"d":"0.50"},{"v":0.608461,"d":"0.61"},{"v":0.413645,"d":"0.41"},{"v":0.0624471156810451,"d":"0.06"},{"v":-4.00122125186864,"d":"-4.00"},{"v":0.000655850445979752,"d":"0.00"},{"v":0.0484068642670326,"d":"0.05"},"down","yes"]
[186972,0,"chr8","+",17972583,18027747,"ENST00000522275",18,2379,"ENSG00000078674","PCM1","GO:0000086(G2/M transition of mitotic cell cycle);GO:0000242(pericentriolar material);GO:0001764(neuron migration);GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0005813(centrosome);GO:0005814(centriole);GO:0005815(microtubule organizing center);GO:0005829(cytosol);GO:0005856(cytoskeleton);GO:0007098(centrosome cycle);GO:0010389(regulation of G2/M transition of mitotic cell cycle);GO:0016020(membrane);GO:0022027(interkinetic nuclear migration);GO:0030030(cell projection organization);GO:0031122(cytoplasmic microtubule organization);GO:0031965(nuclear membrane);GO:0032991(protein-containing complex);GO:0033365(protein localization to organelle);GO:0034451(centriolar satellite);GO:0034453(microtubule anchoring);GO:0034454(microtubule anchoring at centrosome);GO:0035176(social behavior);GO:0035735(intraciliary transport involved in cilium assembly);GO:0035869(ciliary transition zone);GO:0036064(ciliary basal body);GO:0042802(identical protein binding);GO:0042995(cell projection);GO:0045177(apical part of cell);GO:0050768(negative regulation of neurogenesis);GO:0060271(cilium assembly);GO:0071539(protein localization to centrosome);GO:0090316(positive regulation of intracellular protein transport);GO:0097150(neuronal stem cell population maintenance);GO:0097711(ciliary basal body-plasma membrane docking);GO:1905515(non-motile cilium assembly)","NA","NA","NA","pericentriolar material 1 [Source:HGNC Symbol;Acc:HGNC:8727]",{"v":0.117222,"d":"0.12"},{"v":0.121688,"d":"0.12"},0,{"v":0.354829,"d":"0.35"},{"v":2.363864,"d":"2.36"},{"v":8.318951,"d":"8.32"},{"v":0.0216450177229851,"d":"0.02"},{"v":-5.5298212079423,"d":"-5.53"},{"v":0.000656883679704021,"d":"0.00"},{"v":0.0484068642670326,"d":"0.05"},"down","yes"]
[151472,0,"chr4","-",55432476,55449426,"ENST00000511124",7,3932,"ENSG00000134852","CLOCK","GO:0000077(DNA damage checkpoint);GO:0000978(RNA polymerase II proximal promoter sequence-specific DNA binding);GO:0000980(RNA polymerase II distal enhancer sequence-specific DNA binding);GO:0000981(DNA-binding transcription factor activity, RNA polymerase II-specific);GO:0001228(DNA-binding transcription activator activity, RNA polymerase II-specific);GO:0003677(DNA binding);GO:0003700(DNA-binding transcription factor activity);GO:0004402(histone acetyltransferase activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005667(transcription factor complex);GO:0005694(chromosome);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0006355(regulation of transcription, DNA-templated);GO:0006357(regulation of transcription by RNA polymerase II);GO:0006473(protein acetylation);GO:0006974(cellular response to DNA damage stimulus);GO:0007165(signal transduction);GO:0007283(spermatogenesis);GO:0007623(circadian rhythm);GO:0009648(photoperiodism);GO:0016573(histone acetylation);GO:0016740(transferase activity);GO:0016746(transferase activity, transferring acyl groups);GO:0031490(chromatin DNA binding);GO:0032922(circadian regulation of gene expression);GO:0033391(chromatoid body);GO:0042634(regulation of hair cycle);GO:0042752(regulation of circadian rhythm);GO:0043161(proteasome-mediated ubiquitin-dependent protein catabolic process);GO:0043231(intracellular membrane-bounded organelle);GO:0043565(sequence-specific DNA binding);GO:0045892(negative regulation of transcription, DNA-templated);GO:0045893(positive regulation of transcription, DNA-templated);GO:0045944(positive regulation of transcription by RNA polymerase II);GO:0046983(protein dimerization activity);GO:0048511(rhythmic process);GO:0050729(positive regulation of inflammatory response);GO:0050796(regulation of insulin secretion);GO:0051092(positive regulation of NF-kappaB transcription factor activity);GO:0051775(response to redox state);GO:0070888(E-box binding);GO:0071479(cellular response to ionizing radiation);GO:2000074(regulation of type B pancreatic cell development);GO:2000323(negative regulation of glucocorticoid receptor signaling pathway)","04710(Circadian rhythm);04728(Dopaminergic synapse)","K02223","EC:2.3.1.48","clock circadian regulator [Source:HGNC Symbol;Acc:HGNC:2082]",0,0,0,{"v":0.694193,"d":"0.69"},{"v":0.217528,"d":"0.22"},0,"-inf","-inf",{"v":0.000660788684223596,"d":"0.00"},{"v":0.0485960584976584,"d":"0.05"},"down","yes"]
[98729,0,"chr19","-",10333776,10339624,"ENST00000160262",7,1735,"ENSG00000076662","ICAM3","GO:0002223(stimulatory C-type lectin receptor signaling pathway);GO:0005102(signaling receptor binding);GO:0005178(integrin binding);GO:0005515(protein binding);GO:0005886(plasma membrane);GO:0005887(integral component of plasma membrane);GO:0006909(phagocytosis);GO:0007155(cell adhesion);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0030198(extracellular matrix organization);GO:0050776(regulation of immune response);GO:0070062(extracellular exosome);GO:0098609(cell-cell adhesion)","04514(Cell adhesion molecules (CAMs))","NA","NA","intercellular adhesion molecule 3 [Source:HGNC Symbol;Acc:HGNC:5346]",0,0,0,0,{"v":1.006356,"d":"1.01"},{"v":0.957954,"d":"0.96"},"-inf","-inf",{"v":0.000666246105061854,"d":"0.00"},{"v":0.0488984262563579,"d":"0.05"},"down","yes"]
[152546,0,"chr4","+",80184285,80204329,"ENST00000504452",8,3706,"ENSG00000152784","PRDM8","GO:0000981(DNA-binding transcription factor activity, RNA polymerase II-specific);GO:0003676(nucleic acid binding);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0005634(nucleus);GO:0006357(regulation of transcription by RNA polymerase II);GO:0007399(nervous system development);GO:0008168(methyltransferase activity);GO:0014003(oligodendrocyte development);GO:0016740(transferase activity);GO:0032259(methylation);GO:0046872(metal ion binding)","NA","K20797","EC:2.1.1.-","PR/SET domain 8 [Source:HGNC Symbol;Acc:HGNC:13993]",{"v":0.024111,"d":"0.02"},0,{"v":0.040383,"d":"0.04"},{"v":2.442187,"d":"2.44"},{"v":0.025025,"d":"0.03"},{"v":1.823769,"d":"1.82"},{"v":0.0150301294738895,"d":"0.02"},{"v":-6.05599875267389,"d":"-6.06"},{"v":0.000671752152438579,"d":"0.00"},{"v":0.0492031364880919,"d":"0.05"},"down","yes"]
[12324,0,"chr1","+",156082631,156093811,"ENST00000470835",4,472,"ENSG00000160789","LMNA","GO:0005198(structural molecule activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005635(nuclear envelope);GO:0005638(lamin filament);GO:0005652(nuclear lamina);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0005882(intermediate filament);GO:0006606(protein import into nucleus);GO:0006997(nucleus organization);GO:0006998(nuclear envelope organization);GO:0007084(mitotic nuclear envelope reassembly);GO:0008285(negative regulation of cell population proliferation);GO:0010628(positive regulation of gene expression);GO:0016607(nuclear speck);GO:0030334(regulation of cell migration);GO:0030951(establishment or maintenance of microtubule cytoskeleton polarity);GO:0031647(regulation of protein stability);GO:0031965(nuclear membrane);GO:0034504(protein localization to nucleus);GO:0036498(IRE1-mediated unfolded protein response);GO:0055015(ventricular cardiac muscle cell development);GO:0071456(cellular response to hypoxia);GO:0072201(negative regulation of mesenchymal cell proliferation);GO:0090201(negative regulation of release of cytochrome c from mitochondria);GO:0090343(positive regulation of cell aging);GO:1900114(positive regulation of histone H3-K9 trimethylation);GO:1900180(regulation of protein localization to nucleus);GO:1903243(negative regulation of cardiac muscle hypertrophy in response to stress);GO:2001237(negative regulation of extrinsic apoptotic signaling pathway)","04210(Apoptosis);05410(Hypertrophic cardiomyopathy (HCM));05412(Arrhythmogenic right ventricular cardiomyopathy (ARVC));05414(Dilated cardiomyopathy (DCM))","K12641","NA","lamin A/C [Source:HGNC Symbol;Acc:HGNC:6636]",{"v":0.081549,"d":"0.08"},0,{"v":0.031876,"d":"0.03"},{"v":2.442974,"d":"2.44"},{"v":2.369436,"d":"2.37"},{"v":2.136379,"d":"2.14"},{"v":0.0163229880774909,"d":"0.02"},{"v":-5.93695100930479,"d":"-5.94"},{"v":0.000692957877325731,"d":"0.00"},{"v":0.0506542448355006,"d":"0.05"},"down","yes"]
[135273,0,"chr22","-",42597708,42614860,"ENST00000454057",4,579,"ENSG00000100227","POLDIP3","GO:0000346(transcription export complex);GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0005515(protein binding);GO:0005623(cell);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0006405(RNA export from nucleus);GO:0006406(mRNA export from nucleus);GO:0006417(regulation of translation);GO:0016607(nuclear speck);GO:0016973(poly(A)+ mRNA export from nucleus);GO:0031124(mRNA 3'-end processing);GO:0036464(cytoplasmic ribonucleoprotein granule);GO:0044877(protein-containing complex binding);GO:0045727(positive regulation of translation);GO:0051028(mRNA transport)","NA","K22414","NA","DNA polymerase delta interacting protein 3 [Source:HGNC Symbol;Acc:HGNC:23782]",0,0,0,{"v":2.187567,"d":"2.19"},{"v":3.555082,"d":"3.56"},0,"-inf","-inf",{"v":0.000703366541871676,"d":"0.00"},{"v":0.0513118603738916,"d":"0.05"},"down","yes"]
[72114,0,"chr16","+",18984287,19063942,"ENST00000421369",16,4499,"ENSG00000170537","TMC7","GO:0005216(ion channel activity);GO:0005887(integral component of plasma membrane);GO:0006811(ion transport);GO:0008381(mechanosensitive ion channel activity);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0034220(ion transmembrane transport);GO:0055085(transmembrane transport)","NA","K21988","NA","transmembrane channel like 7 [Source:HGNC Symbol;Acc:HGNC:23000]",0,0,0,0,{"v":0.343386,"d":"0.34"},{"v":0.394517,"d":"0.39"},"-inf","-inf",{"v":0.000713649076794126,"d":"0.00"},{"v":0.0519576572343299,"d":"0.05"},"down","yes"]
[77011,0,"chr16","+",69951277,69961400,"ENST00000565705",8,1523,"ENSG00000157322","CLEC18A","GO:0005515(protein binding);GO:0005576(extracellular region);GO:0005615(extracellular space);GO:0005768(endosome);GO:0005783(endoplasmic reticulum);GO:0005794(Golgi apparatus);GO:0030246(carbohydrate binding);GO:0030247(polysaccharide binding)","NA","K22682","NA","C-type lectin domain family 18 member A [Source:HGNC Symbol;Acc:HGNC:30388]",0,{"v":0.725837,"d":"0.73"},{"v":1.538871,"d":"1.54"},0,0,0,"inf","inf",{"v":0.000718566727374824,"d":"0.00"},{"v":0.0522110584110547,"d":"0.05"},"up","yes"]
[60831,0,"chr14","+",103629241,103693743,"ENST00000246489",16,2294,"ENSG00000126214","KLC1","GO:0003774(motor activity);GO:0003777(microtubule motor activity);GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005856(cytoskeleton);GO:0005871(kinesin complex);GO:0005874(microtubule);GO:0006890(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum);GO:0007018(microtubule-based movement);GO:0016020(membrane);GO:0016032(viral process);GO:0019886(antigen processing and presentation of exogenous peptide antigen via MHC class II);GO:0030426(growth cone);GO:0031410(cytoplasmic vesicle);GO:0035617(stress granule disassembly);GO:0042995(cell projection)","05132(Salmonella infection)","K10407","NA","kinesin light chain 1 [Source:HGNC Symbol;Acc:HGNC:6387]",{"v":4.639924,"d":"4.64"},{"v":7.785648,"d":"7.79"},{"v":5.570771,"d":"5.57"},{"v":0.729019,"d":"0.73"},{"v":0.473101,"d":"0.47"},{"v":0.529459,"d":"0.53"},{"v":10.3930245169293,"d":"10.39"},{"v":3.37754365486576,"d":"3.38"},{"v":0.00072596957000586,"d":"0.00"},{"v":0.0526436616333591,"d":"0.05"},"up","yes"]
[37779,0,"chr11","-",125097486,125111604,"ENST00000529583",7,848,"ENSG00000150433","TMEM218","GO:0005515(protein binding);GO:0005929(cilium);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0042995(cell projection)","NA","NA","NA","transmembrane protein 218 [Source:HGNC Symbol;Acc:HGNC:27344]",0,{"v":2.897857,"d":"2.90"},{"v":1.196689,"d":"1.20"},0,0,0,"inf","inf",{"v":0.00072751231935005,"d":"0.00"},{"v":0.0526504433505724,"d":"0.05"},"up","yes"]
[21693,0,"chr10","+",69802424,69958701,"ENST00000517713",37,2007,"ENSG00000197467","COL13A1","GO:0001503(ossification);GO:0001763(morphogenesis of a branching structure);GO:0001958(endochondral ossification);GO:0005201(extracellular matrix structural constituent);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0005581(collagen trimer);GO:0005600(collagen type XIII trimer);GO:0005615(extracellular space);GO:0005788(endoplasmic reticulum lumen);GO:0005886(plasma membrane);GO:0005911(cell-cell junction);GO:0007155(cell adhesion);GO:0007160(cell-matrix adhesion);GO:0007275(multicellular organism development);GO:0008201(heparin binding);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0030020(extracellular matrix structural constituent conferring tensile strength);GO:0030054(cell junction);GO:0030154(cell differentiation);GO:0030198(extracellular matrix organization);GO:0030574(collagen catabolic process);GO:0031012(extracellular matrix);GO:0045202(synapse);GO:0045211(postsynaptic membrane);GO:0062023(collagen-containing extracellular matrix);GO:0098609(cell-cell adhesion)","04974(Protein digestion and absorption)","NA","NA","collagen type XIII alpha 1 chain [Source:HGNC Symbol;Acc:HGNC:2190]",0,0,0,{"v":1.090377,"d":"1.09"},{"v":0.551254,"d":"0.55"},0,"-inf","-inf",{"v":0.000730386594687525,"d":"0.00"},{"v":0.0527533697514867,"d":"0.05"},"down","yes"]
[22924,0,"chr10","-",89213575,89252039,"ENST00000456827",8,2527,"ENSG00000107798","LIPA","GO:0000902(cell morphogenesis);GO:0001650(fibrillar center);GO:0001816(cytokine production);GO:0004771(sterol esterase activity);GO:0005764(lysosome);GO:0006629(lipid metabolic process);GO:0006954(inflammatory response);GO:0008283(cell population proliferation);GO:0016042(lipid catabolic process);GO:0016125(sterol metabolic process);GO:0016298(lipase activity);GO:0016787(hydrolase activity);GO:0016788(hydrolase activity, acting on ester bonds);GO:0030324(lung development);GO:0034383(low-density lipoprotein particle clearance);GO:0043202(lysosomal lumen);GO:0043231(intracellular membrane-bounded organelle);GO:0044255(cellular lipid metabolic process);GO:0048771(tissue remodeling);GO:0048873(homeostasis of number of cells within a tissue)","00100(Steroid biosynthesis);04142(Lysosome);04979(Cholesterol metabolism)","K01052","EC:3.1.1.13","lipase A, lysosomal acid type [Source:HGNC Symbol;Acc:HGNC:6617]",{"v":0.532529,"d":"0.53"},{"v":0.560585,"d":"0.56"},{"v":0.558713,"d":"0.56"},{"v":0.533198,"d":"0.53"},{"v":13.328903,"d":"13.33"},{"v":9.946553,"d":"9.95"},{"v":0.0693792685634392,"d":"0.07"},{"v":-3.84935155879963,"d":"-3.85"},{"v":0.000741871168693102,"d":"0.00"},{"v":0.0534765467432944,"d":"0.05"},"down","yes"]
[71451,0,"chr16","-",10928891,10942131,"ENST00000469379",3,1393,"ENSG00000182108","DEXI","NA","NA","NA","NA","Dexi homolog [Source:HGNC Symbol;Acc:HGNC:13267]",{"v":0.066257,"d":"0.07"},{"v":14.42058,"d":"14.42"},{"v":7.506421,"d":"7.51"},{"v":0.23225,"d":"0.23"},{"v":0.229893,"d":"0.23"},{"v":0.166286,"d":"0.17"},{"v":34.9972041392106,"d":"35.00"},{"v":5.12916776735614,"d":"5.13"},{"v":0.000743659675067735,"d":"0.00"},{"v":0.0534993188023976,"d":"0.05"},"up","yes"]
[115849,0,"chr2","+",102736911,102817420,"ENST00000409173",6,3198,"ENSG00000170417","TMEM182","GO:0005515(protein binding);GO:0016020(membrane);GO:0016021(integral component of membrane)","NA","NA","NA","transmembrane protein 182 [Source:HGNC Symbol;Acc:HGNC:26391]",0,0,0,{"v":0.289681,"d":"0.29"},{"v":0.264652,"d":"0.26"},{"v":0.000125,"d":"0.00"},"-inf","-inf",{"v":0.000747254774130842,"d":"0.00"},{"v":0.0536517113521215,"d":"0.05"},"down","yes"]
[65257,0,"chr15","-",64156778,64163006,"ENST00000558492",3,381,"ENSG00000166794","PPIB","GO:0000413(protein peptidyl-prolyl isomerization);GO:0003723(RNA binding);GO:0003755(peptidyl-prolyl cis-trans isomerase activity);GO:0005515(protein binding);GO:0005518(collagen binding);GO:0005634(nucleus);GO:0005783(endoplasmic reticulum);GO:0005788(endoplasmic reticulum lumen);GO:0005790(smooth endoplasmic reticulum);GO:0005925(focal adhesion);GO:0006457(protein folding);GO:0016018(cyclosporin A binding);GO:0016020(membrane);GO:0016853(isomerase activity);GO:0032991(protein-containing complex);GO:0034663(endoplasmic reticulum chaperone complex);GO:0040018(positive regulation of multicellular organism growth);GO:0042026(protein refolding);GO:0042470(melanosome);GO:0044794(positive regulation by host of viral process);GO:0044829(positive regulation by host of viral genome replication);GO:0048471(perinuclear region of cytoplasm);GO:0050821(protein stabilization);GO:0051082(unfolded protein binding);GO:0060348(bone development);GO:0061077(chaperone-mediated protein folding);GO:0070062(extracellular exosome);GO:0070063(RNA polymerase binding)","NA","NA","NA","peptidylprolyl isomerase B [Source:HGNC Symbol;Acc:HGNC:9255]",0,{"v":3.463119,"d":"3.46"},{"v":5.205072,"d":"5.21"},0,0,0,"inf","inf",{"v":0.000752136972514987,"d":"0.00"},{"v":0.0538957321725236,"d":"0.05"},"up","yes"]
[136424,0,"chr3","-",8750408,8769617,"ENST00000316793",4,4364,"ENSG00000180914","OXTR","GO:0001967(suckling behavior);GO:0001975(response to amphetamine);GO:0001992(regulation of systemic arterial blood pressure by vasopressin);GO:0004930(G protein-coupled receptor activity);GO:0004990(oxytocin receptor activity);GO:0005000(vasopressin receptor activity);GO:0005886(plasma membrane);GO:0005887(integral component of plasma membrane);GO:0005902(microvillus);GO:0005913(cell-cell adherens junction);GO:0006936(muscle contraction);GO:0007165(signal transduction);GO:0007166(cell surface receptor signaling pathway);GO:0007186(G protein-coupled receptor signaling pathway);GO:0007204(positive regulation of cytosolic calcium ion concentration);GO:0007507(heart development);GO:0007565(female pregnancy);GO:0007595(lactation);GO:0007613(memory);GO:0010701(positive regulation of norepinephrine secretion);GO:0014070(response to organic cyclic compound);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016324(apical plasma membrane);GO:0017046(peptide hormone binding);GO:0021537(telencephalon development);GO:0030431(sleep);GO:0032230(positive regulation of synaptic transmission, GABAergic);GO:0032355(response to estradiol);GO:0032570(response to progesterone);GO:0032870(cellular response to hormone stimulus);GO:0034059(response to anoxia);GO:0034097(response to cytokine);GO:0035176(social behavior);GO:0042220(response to cocaine);GO:0042493(response to drug);GO:0042711(maternal behavior);GO:0042713(sperm ejaculation);GO:0042755(eating behavior);GO:0043434(response to peptide hormone);GO:0044058(regulation of digestive system process);GO:0044849(estrous cycle);GO:0045777(positive regulation of blood pressure);GO:0045907(positive regulation of vasoconstriction);GO:0048545(response to steroid hormone);GO:0048565(digestive tract development);GO:0051965(positive regulation of synapse assembly);GO:0051968(positive regulation of synaptic transmission, glutamatergic);GO:0060137(maternal process involved in parturition);GO:0060406(positive regulation of penile erection);GO:0060455(negative regulation of gastric acid secretion);GO:0070371(ERK1 and ERK2 cascade);GO:0070474(positive regulation of uterine smooth muscle contraction);GO:0120162(positive regulation of cold-induced thermogenesis)","04020(Calcium signaling pathway);04024(cAMP signaling pathway);04080(Neuroactive ligand-receptor interaction);04921(Oxytocin signaling pathway)","K04229","NA","oxytocin receptor [Source:HGNC Symbol;Acc:HGNC:8529]",{"v":0.351556,"d":"0.35"},{"v":0.393075,"d":"0.39"},{"v":0.295699,"d":"0.30"},{"v":3.363032,"d":"3.36"},{"v":3.486778,"d":"3.49"},{"v":2.861836,"d":"2.86"},{"v":0.107121902919443,"d":"0.11"},{"v":-3.2226746007699,"d":"-3.22"},{"v":0.000761414999047237,"d":"0.00"},{"v":0.054453163219264,"d":"0.05"},"down","yes"]
[162319,0,"chr5","-",128257909,128538245,"ENST00000262464",65,10927,"ENSG00000138829","FBN2","GO:0001527(microfibril);GO:0005201(extracellular matrix structural constituent);GO:0005509(calcium ion binding);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0030023(extracellular matrix constituent conferring elasticity);GO:0030198(extracellular matrix organization);GO:0030326(embryonic limb morphogenesis);GO:0030501(positive regulation of bone mineralization);GO:0031012(extracellular matrix);GO:0035108(limb morphogenesis);GO:0035583(sequestering of TGFbeta in extracellular matrix);GO:0043010(camera-type eye development);GO:0045669(positive regulation of osteoblast differentiation);GO:0048048(embryonic eye morphogenesis);GO:0060346(bone trabecula formation);GO:0062023(collagen-containing extracellular matrix)","NA","NA","NA","fibrillin 2 [Source:HGNC Symbol;Acc:HGNC:3604]",{"v":57.49432,"d":"57.49"},{"v":71.256042,"d":"71.26"},{"v":60.427109,"d":"60.43"},{"v":296.346863,"d":"296.35"},{"v":278.355835,"d":"278.36"},{"v":244.236267,"d":"244.24"},{"v":0.231003138310802,"d":"0.23"},{"v":-2.11401564326908,"d":"-2.11"},{"v":0.000766762567913263,"d":"0.00"},{"v":0.0547278665860292,"d":"0.05"},"down","yes"]
[25566,0,"chr11","-",216206,236354,"ENST00000525319",7,1475,"ENSG00000142082","SIRT3","GO:0003950(NAD+ ADP-ribosyltransferase activity);GO:0005515(protein binding);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0005739(mitochondrion);GO:0005759(mitochondrial matrix);GO:0006471(protein ADP-ribosylation);GO:0006476(protein deacetylation);GO:0007005(mitochondrion organization);GO:0007568(aging);GO:0008270(zinc ion binding);GO:0009060(aerobic respiration);GO:0016575(histone deacetylation);GO:0016787(hydrolase activity);GO:0017136(NAD-dependent histone deacetylase activity);GO:0019899(enzyme binding);GO:0032024(positive regulation of insulin secretion);GO:0032991(protein-containing complex);GO:0034983(peptidyl-lysine deacetylation);GO:0043565(sequence-specific DNA binding);GO:0046872(metal ion binding);GO:0070373(negative regulation of ERK1 and ERK2 cascade);GO:0070403(NAD+ binding);GO:2000378(negative regulation of reactive oxygen species metabolic process)","05230(Central carbon metabolism in cancer)","K11413","EC:3.5.1.-","sirtuin 3 [Source:HGNC Symbol;Acc:HGNC:14931]",{"v":1.062251,"d":"1.06"},{"v":2.213402,"d":"2.21"},0,0,0,{"v":0.000195,"d":"0.00"},{"v":16798.2205128205,"d":"16798.22"},{"v":14.0360207915235,"d":"14.04"},{"v":0.000776181797716151,"d":"0.00"},{"v":0.055291538649074,"d":"0.06"},"up","yes"]
[44649,0,"chr12","-",57249609,57296484,"ENST00000548184",15,2107,"ENSG00000258830","AC137834","GO:0003676(nucleic acid binding)","NA","NA","NA","novel transcript",{"v":0.393895,"d":"0.39"},{"v":0.318936,"d":"0.32"},{"v":0.539989,"d":"0.54"},{"v":0.014332,"d":"0.01"},0,0,{"v":87.4141780630756,"d":"87.41"},{"v":6.44979539020122,"d":"6.45"},{"v":0.000779790959568112,"d":"0.00"},{"v":0.0554399326049109,"d":"0.06"},"up","yes"]
[103891,0,"chr19","-",40233841,40265312,"ENST00000311278",12,1393,"ENSG00000105221","AKT2","GO:0000166(nucleotide binding);GO:0001934(positive regulation of protein phosphorylation);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005515(protein binding);GO:0005524(ATP binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0005768(endosome);GO:0005769(early endosome);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0005938(cell cortex);GO:0005975(carbohydrate metabolic process);GO:0005977(glycogen metabolic process);GO:0005978(glycogen biosynthetic process);GO:0006006(glucose metabolic process);GO:0006417(regulation of translation);GO:0006464(cellular protein modification process);GO:0006468(protein phosphorylation);GO:0006915(apoptotic process);GO:0007165(signal transduction);GO:0007275(multicellular organism development);GO:0008284(positive regulation of cell population proliferation);GO:0008286(insulin receptor signaling pathway);GO:0008643(carbohydrate transport);GO:0010748(negative regulation of long-chain fatty acid import across plasma membrane);GO:0010907(positive regulation of glucose metabolic process);GO:0010918(positive regulation of mitochondrial membrane potential);GO:0016020(membrane);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0016740(transferase activity);GO:0018105(peptidyl-serine phosphorylation);GO:0030334(regulation of cell migration);GO:0030335(positive regulation of cell migration);GO:0031340(positive regulation of vesicle fusion);GO:0032000(positive regulation of fatty acid beta-oxidation);GO:0032287(peripheral nervous system myelin maintenance);GO:0032587(ruffle membrane);GO:0032869(cellular response to insulin stimulus);GO:0032991(protein-containing complex);GO:0035556(intracellular signal transduction);GO:0043066(negative regulation of apoptotic process);GO:0043231(intracellular membrane-bounded organelle);GO:0043491(protein kinase B signaling);GO:0045444(fat cell differentiation);GO:0045725(positive regulation of glycogen biosynthetic process);GO:0046326(positive regulation of glucose import);GO:0046872(metal ion binding);GO:0060644(mammary gland epithelial cell differentiation);GO:0065002(intracellular protein transmembrane transport);GO:0071156(regulation of cell cycle arrest);GO:0071486(cellular response to high light intensity);GO:0072659(protein localization to plasma membrane);GO:0090314(positive regulation of protein targeting to membrane);GO:0090630(activation of GTPase activity);GO:0097473(retinal rod cell apoptotic process);GO:2000147(positive regulation of cell motility)","01521(EGFR tyrosine kinase inhibitor resistance);01522(Endocrine resistance);01524(Platinum drug resistance);04010(MAPK signaling pathway);04012(ErbB signaling pathway);04014(Ras signaling pathway);04015(Rap1 signaling pathway);04022(cGMP-PKG signaling pathway);04024(cAMP signaling pathway);04062(Chemokine signaling pathway);04066(HIF-1 signaling pathway);04068(FoxO signaling pathway);04071(Sphingolipid signaling pathway);04072(Phospholipase D signaling pathway);04140(Autophagy - animal);04150(mTOR signaling pathway);04151(PI3K-Akt signaling pathway);04152(AMPK signaling pathway);04210(Apoptosis);04211(Longevity regulating pathway);04213(Longevity regulating pathway - multiple species);04218(Cellular senescence);04261(Adrenergic signaling in cardiomyocytes);04370(VEGF signaling pathway);04371(Apelin signaling pathway);04380(Osteoclast differentiation);04510(Focal adhesion);04550(Signaling pathways regulating pluripotency of stem cells);04611(Platelet activation);04620(Toll-like receptor signaling pathway);04625(C-type lectin receptor signaling pathway);04630(Jak-STAT signaling pathway);04660(T cell receptor signaling pathway);04662(B cell receptor signaling pathway);04664(Fc epsilon RI signaling pathway);04666(Fc gamma R-mediated phagocytosis);04668(TNF signaling pathway);04722(Neurotrophin signaling pathway);04725(Cholinergic synapse);04728(Dopaminergic synapse);04910(Insulin signaling pathway);04914(Progesterone-mediated oocyte maturation);04915(Estrogen signaling pathway);04917(Prolactin signaling pathway);04919(Thyroid hormone signaling pathway);04920(Adipocytokine signaling pathway);04922(Glucagon signaling pathway);04923(Regulation of lipolysis in adipocytes);04926(Relaxin signaling pathway);04931(Insulin resistance);04932(Non-alcoholic fatty liver disease (NAFLD));04933(AGE-RAGE signaling pathway in diabetic complications);04973(Carbohydrate digestion and absorption);05142(Chagas disease (American trypanosomiasis));05145(Toxoplasmosis);05152(Tuberculosis);05160(Hepatitis C);05161(Hepatitis B);05162(Measles);05163(Human cytomegalovirus infection);05164(Influenza A);05165(Human papillomavirus infection);05166(Human T-cell leukemia virus 1 infection);05167(Kaposi sarcoma-associated herpesvirus infection);05168(Herpes simplex virus 1 infection);05169(Epstein-Barr virus infection);05170(Human immunodeficiency virus 1 infection);05200(Pathways in cancer);05205(Proteoglycans in cancer);05210(Colorectal cancer);05211(Renal cell carcinoma);05212(Pancreatic cancer);05213(Endometrial cancer);05214(Glioma);05215(Prostate cancer);05218(Melanoma);05220(Chronic myeloid leukemia);05221(Acute myeloid leukemia);05222(Small cell lung cancer);05223(Non-small cell lung cancer);05224(Breast cancer);05225(Hepatocellular carcinoma);05226(Gastric cancer);05230(Central carbon metabolism in cancer);05231(Choline metabolism in cancer);05418(Fluid shear stress and atherosclerosis)","NA","NA","AKT serine/threonine kinase 2 [Source:HGNC Symbol;Acc:HGNC:392]",{"v":0.000175,"d":"0.00"},{"v":0.002284,"d":"0.00"},{"v":0.042259,"d":"0.04"},{"v":0.121592,"d":"0.12"},{"v":1.095961,"d":"1.10"},{"v":2.145007,"d":"2.15"},{"v":0.0132987961553102,"d":"0.01"},{"v":-6.23256053497839,"d":"-6.23"},{"v":0.000782427819191934,"d":"0.00"},{"v":0.0555187552172714,"d":"0.06"},"down","yes"]
[173095,0,"chr6","-",110609978,110815637,"ENST00000323817",14,6067,"ENSG00000155111","CDK19","GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0004693(cyclin-dependent protein serine/threonine kinase activity);GO:0005524(ATP binding);GO:0005634(nucleus);GO:0005829(cytosol);GO:0006468(protein phosphorylation);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0016592(mediator complex);GO:0016740(transferase activity);GO:0043065(positive regulation of apoptotic process);GO:0050729(positive regulation of inflammatory response);GO:0051726(regulation of cell cycle);GO:0071222(cellular response to lipopolysaccharide)","NA","K02208","2.7.11.23;EC:2.7.11.22","cyclin dependent kinase 19 [Source:HGNC Symbol;Acc:HGNC:19338]",{"v":0.002989,"d":"0.00"},0,{"v":0.00185,"d":"0.00"},{"v":0.153471,"d":"0.15"},{"v":0.321871,"d":"0.32"},{"v":0.018504,"d":"0.02"},{"v":0.00979860118336485,"d":"0.01"},{"v":-6.67320847521608,"d":"-6.67"},{"v":0.000797867087790682,"d":"0.00"},{"v":0.0564063014911678,"d":"0.06"},"down","yes"]
[128770,0,"chr20","-",63743666,63831214,"ENST00000245663",5,5185,"ENSG00000130584","ZBTB46","GO:0000981(DNA-binding transcription factor activity, RNA polymerase II-specific);GO:0003676(nucleic acid binding);GO:0005515(protein binding);GO:0005634(nucleus);GO:0006357(regulation of transcription by RNA polymerase II);GO:0030853(negative regulation of granulocyte differentiation);GO:0045650(negative regulation of macrophage differentiation);GO:0045656(negative regulation of monocyte differentiation);GO:0046872(metal ion binding);GO:2001199(negative regulation of dendritic cell differentiation);GO:2001200(positive regulation of dendritic cell differentiation)","NA","K10517","NA","zinc finger and BTB domain containing 46 [Source:HGNC Symbol;Acc:HGNC:16094]",0,0,0,{"v":0.292723,"d":"0.29"},0,{"v":0.267631,"d":"0.27"},"-inf","-inf",{"v":0.000799247335545383,"d":"0.00"},{"v":0.0564063014911678,"d":"0.06"},"down","yes"]
[14483,0,"chr1","+",181033425,181061938,"ENST00000434571",5,7479,"ENSG00000153029","MR1","GO:0002367(cytokine production involved in immune response);GO:0002376(immune system process);GO:0002474(antigen processing and presentation of peptide antigen via MHC class I);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0005615(extracellular space);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005886(plasma membrane);GO:0006955(immune response);GO:0009897(external side of plasma membrane);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0032393(MHC class I receptor activity);GO:0032611(interleukin-1 beta production);GO:0032620(interleukin-17 production);GO:0042612(MHC class I protein complex);GO:0045087(innate immune response);GO:0050829(defense response to Gram-negative bacterium)","NA","NA","NA","major histocompatibility complex, class I-related [Source:HGNC Symbol;Acc:HGNC:4975]",0,0,0,0,{"v":0.300656,"d":"0.30"},{"v":0.133587,"d":"0.13"},"-inf","-inf",{"v":0.000799593869197671,"d":"0.00"},{"v":0.0564063014911678,"d":"0.06"},"down","yes"]
[187411,0,"chr8","+",22580490,22598025,"ENST00000265810",10,4592,"ENSG00000120913","PDLIM2","GO:0005515(protein binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005856(cytoskeleton);GO:0046872(metal ion binding)","NA","NA","NA","PDZ and LIM domain 2 [Source:HGNC Symbol;Acc:HGNC:13992]",{"v":0.055979,"d":"0.06"},{"v":0.051279,"d":"0.05"},{"v":0.08793,"d":"0.09"},{"v":0.123586,"d":"0.12"},{"v":2.073639,"d":"2.07"},{"v":1.824426,"d":"1.82"},{"v":0.0485342959893834,"d":"0.05"},{"v":-4.36485162457735,"d":"-4.36"},{"v":0.000801722525979501,"d":"0.00"},{"v":0.0564468592419288,"d":"0.06"},"down","yes"]
[176652,0,"chr7","-",6798941,6826770,"ENST00000626257",14,2211,"ENSG00000146574","CCZ1B","GO:0005764(lysosome);GO:0005765(lysosomal membrane);GO:0005829(cytosol);GO:0016020(membrane);GO:0016192(vesicle-mediated transport);GO:0016235(aggresome);GO:0035658(Mon1-Ccz1 complex);GO:0043231(intracellular membrane-bounded organelle)","NA","NA","NA","CCZ1 homolog B, vacuolar protein trafficking and biogenesis associated [Source:HGNC Symbol;Acc:HGNC:21717]",0,0,0,{"v":0.576129,"d":"0.58"},0,{"v":0.733827,"d":"0.73"},"-inf","-inf",{"v":0.000816140929414673,"d":"0.00"},{"v":0.0573508703397197,"d":"0.06"},"down","yes"]
[73130,0,"chr16","-",28482513,28491946,"ENST00000565778",7,688,"ENSG00000188603","CLN3","GO:0000139(Golgi membrane);GO:0001508(action potential);GO:0001575(globoside metabolic process);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005739(mitochondrion);GO:0005764(lysosome);GO:0005765(lysosomal membrane);GO:0005768(endosome);GO:0005769(early endosome);GO:0005770(late endosome);GO:0005776(autophagosome);GO:0005783(endoplasmic reticulum);GO:0005794(Golgi apparatus);GO:0005795(Golgi stack);GO:0005802(trans-Golgi network);GO:0005886(plasma membrane);GO:0005901(caveola);GO:0006520(cellular amino acid metabolic process);GO:0006672(ceramide metabolic process);GO:0006678(glucosylceramide metabolic process);GO:0006681(galactosylceramide metabolic process);GO:0006684(sphingomyelin metabolic process);GO:0006898(receptor-mediated endocytosis);GO:0007040(lysosome organization);GO:0007042(lysosomal lumen acidification);GO:0008021(synaptic vesicle);GO:0008306(associative learning);GO:0015809(arginine transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016236(macroautophagy);GO:0016485(protein processing);GO:0030163(protein catabolic process);GO:0030176(integral component of endoplasmic reticulum membrane);GO:0035235(ionotropic glutamate receptor signaling pathway);GO:0035752(lysosomal lumen pH elevation);GO:0042133(neurotransmitter metabolic process);GO:0042987(amyloid precursor protein catabolic process);GO:0043005(neuron projection);GO:0043066(negative regulation of apoptotic process);GO:0043086(negative regulation of catalytic activity);GO:0043524(negative regulation of neuron apoptotic process);GO:0045121(membrane raft);GO:0045861(negative regulation of proteolysis);GO:0047496(vesicle transport along microtubule);GO:0050885(neuromuscular process controlling balance);GO:0051082(unfolded protein binding);GO:0051453(regulation of intracellular pH);GO:0051480(regulation of cytosolic calcium ion concentration);GO:0061024(membrane organization);GO:0097352(autophagosome maturation)","04142(Lysosome)","NA","NA","CLN3, battenin [Source:HGNC Symbol;Acc:HGNC:2074]",0,0,0,{"v":1.878559,"d":"1.88"},0,{"v":2.279617,"d":"2.28"},"-inf","-inf",{"v":0.000828242582561798,"d":"0.00"},{"v":0.058088905452645,"d":"0.06"},"down","yes"]
[63603,0,"chr15","-",43772620,43776966,"ENST00000319359",11,1755,"ENSG00000128886","ELL3","GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005730(nucleolus);GO:0006354(DNA-templated transcription, elongation);GO:0006366(transcription by RNA polymerase II);GO:0006368(transcription elongation from RNA polymerase II promoter);GO:0007283(spermatogenesis);GO:0008023(transcription elongation factor complex);GO:0010717(regulation of epithelial to mesenchymal transition);GO:0032786(positive regulation of DNA-templated transcription, elongation);GO:0035326(enhancer binding);GO:0042795(snRNA transcription by RNA polymerase II);GO:0045944(positive regulation of transcription by RNA polymerase II);GO:0048863(stem cell differentiation);GO:0050769(positive regulation of neurogenesis);GO:1901797(negative regulation of signal transduction by p53 class mediator);GO:1902166(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator);GO:2000179(positive regulation of neural precursor cell proliferation)","NA","K15183","NA","elongation factor for RNA polymerase II 3 [Source:HGNC Symbol;Acc:HGNC:23113]",{"v":0.033698,"d":"0.03"},{"v":0.025076,"d":"0.03"},0,{"v":0.811016,"d":"0.81"},{"v":0.709414,"d":"0.71"},{"v":0.859456,"d":"0.86"},{"v":0.0246961409075897,"d":"0.02"},{"v":-5.33957057016949,"d":"-5.34"},{"v":0.000837444157919943,"d":"0.00"},{"v":0.0585762518890918,"d":"0.06"},"down","yes"]
[33838,0,"chr11","+",72227881,72239105,"ENST00000541756",27,4656,"ENSG00000165458","INPPL1","GO:0001958(endochondral ossification);GO:0002376(immune system process);GO:0003779(actin binding);GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0005794(Golgi apparatus);GO:0005829(cytosol);GO:0005856(cytoskeleton);GO:0005886(plasma membrane);GO:0006006(glucose metabolic process);GO:0006661(phosphatidylinositol biosynthetic process);GO:0006897(endocytosis);GO:0007015(actin filament organization);GO:0007155(cell adhesion);GO:0008285(negative regulation of cell population proliferation);GO:0009791(post-embryonic development);GO:0010629(negative regulation of gene expression);GO:0016020(membrane);GO:0016787(hydrolase activity);GO:0017124(SH3 domain binding);GO:0019221(cytokine-mediated signaling pathway);GO:0030027(lamellipodium);GO:0030175(filopodium);GO:0032868(response to insulin);GO:0042169(SH2 domain binding);GO:0042995(cell projection);GO:0043647(inositol phosphate metabolic process);GO:0044255(cellular lipid metabolic process);GO:0046856(phosphatidylinositol dephosphorylation);GO:0097178(ruffle assembly)","00562(Inositol phosphate metabolism);04070(Phosphatidylinositol signaling system);04662(B cell receptor signaling pathway);04666(Fc gamma R-mediated phagocytosis);04910(Insulin signaling pathway)","K15909","EC:3.1.3.86","inositol polyphosphate phosphatase like 1 [Source:HGNC Symbol;Acc:HGNC:6080]",{"v":1.654894,"d":"1.65"},{"v":0.392011,"d":"0.39"},{"v":0.525815,"d":"0.53"},{"v":3.776122,"d":"3.78"},{"v":2.717559,"d":"2.72"},{"v":20.002781,"d":"20.00"},{"v":0.0970967369152908,"d":"0.10"},{"v":-3.36443337729432,"d":"-3.36"},{"v":0.000838415936755512,"d":"0.00"},{"v":0.0585762518890918,"d":"0.06"},"down","yes"]
[146641,0,"chr3","-",177022926,177098493,"ENST00000631253",15,4186,"ENSG00000177565","TBL1XR1","GO:0000118(histone deacetylase complex);GO:0000122(negative regulation of transcription by RNA polymerase II);GO:0001835(blastocyst hatching);GO:0002021(response to dietary excess);GO:0003677(DNA binding);GO:0003714(transcription corepressor activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0006325(chromatin organization);GO:0006357(regulation of transcription by RNA polymerase II);GO:0008013(beta-catenin binding);GO:0010468(regulation of gene expression);GO:0016042(lipid catabolic process);GO:0016575(histone deacetylation);GO:0017053(transcriptional repressor complex);GO:0019216(regulation of lipid metabolic process);GO:0035264(multicellular organism growth);GO:0042393(histone binding);GO:0043161(proteasome-mediated ubiquitin-dependent protein catabolic process);GO:0044212(transcription regulatory region DNA binding);GO:0045892(negative regulation of transcription, DNA-templated);GO:0045893(positive regulation of transcription, DNA-templated);GO:0045944(positive regulation of transcription by RNA polymerase II);GO:0047485(protein N-terminus binding);GO:0050872(white fat cell differentiation);GO:0060612(adipose tissue development);GO:0060613(fat pad development);GO:0072686(mitotic spindle);GO:0090207(regulation of triglyceride metabolic process);GO:0090263(positive regulation of canonical Wnt signaling pathway)","04310(Wnt signaling pathway)","K04508","NA","transducin beta like 1 X-linked receptor 1 [Source:HGNC Symbol;Acc:HGNC:29529]",0,{"v":0.550903,"d":"0.55"},{"v":0.216057,"d":"0.22"},0,0,0,"inf","inf",{"v":0.000853325778059981,"d":"0.00"},{"v":0.0595035038712459,"d":"0.06"},"up","yes"]
[190858,0,"chr8","+",91249319,91398155,"ENST00000276609",19,5237,"ENSG00000147606","SLC26A7","GO:0001696(gastric acid secretion);GO:0005253(anion channel activity);GO:0005254(chloride channel activity);GO:0005737(cytoplasm);GO:0005768(endosome);GO:0005886(plasma membrane);GO:0005887(integral component of plasma membrane);GO:0006811(ion transport);GO:0006820(anion transport);GO:0006821(chloride transport);GO:0008271(secondary active sulfate transmembrane transporter activity);GO:0008272(sulfate transport);GO:0008509(anion transmembrane transporter activity);GO:0015106(bicarbonate transmembrane transporter activity);GO:0015108(chloride transmembrane transporter activity);GO:0015116(sulfate transmembrane transporter activity);GO:0015301(anion:anion antiporter activity);GO:0015701(bicarbonate transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016323(basolateral plasma membrane);GO:0019531(oxalate transmembrane transporter activity);GO:0019532(oxalate transport);GO:0055038(recycling endosome membrane);GO:0055085(transmembrane transport);GO:0098656(anion transmembrane transport);GO:1902358(sulfate transmembrane transport);GO:1902476(chloride transmembrane transport)","04971(Gastric acid secretion)","K13962","NA","solute carrier family 26 member 7 [Source:HGNC Symbol;Acc:HGNC:14467]",0,{"v":0.236753,"d":"0.24"},{"v":0.353572,"d":"0.35"},0,0,0,"inf","inf",{"v":0.000859287127749443,"d":"0.00"},{"v":0.0598044087186538,"d":"0.06"},"up","yes"]
[44320,0,"chr12","-",56285962,56316044,"ENST00000547423",5,566,"ENSG00000144785","AC073896","GO:0005783(endoplasmic reticulum);GO:0010629(negative regulation of gene expression);GO:0010988(regulation of low-density lipoprotein particle clearance);GO:0045716(positive regulation of low-density lipoprotein particle receptor biosynthetic process)","NA","NA","NA","novel protein",{"v":2.551939,"d":"2.55"},{"v":2.741752,"d":"2.74"},0,0,0,0,"inf","inf",{"v":0.000866646873491831,"d":"0.00"},{"v":0.0602013019387347,"d":"0.06"},"up","yes"]
[122965,0,"chr2","+",230864980,230879248,"ENST00000326407",5,1888,"ENSG00000135916","ITM2C","GO:0001540(amyloid-beta binding);GO:0005515(protein binding);GO:0005524(ATP binding);GO:0005764(lysosome);GO:0005765(lysosomal membrane);GO:0005794(Golgi apparatus);GO:0005886(plasma membrane);GO:0010977(negative regulation of neuron projection development);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0030182(neuron differentiation);GO:0042985(negative regulation of amyloid precursor protein biosynthetic process);GO:0048471(perinuclear region of cytoplasm);GO:0070062(extracellular exosome);GO:2001238(positive regulation of extrinsic apoptotic signaling pathway)","NA","K18265","NA","integral membrane protein 2C [Source:HGNC Symbol;Acc:HGNC:6175]",{"v":37.355392,"d":"37.36"},{"v":39.781311,"d":"39.78"},{"v":2.67186,"d":"2.67"},{"v":2.854617,"d":"2.85"},{"v":3.305857,"d":"3.31"},{"v":2.357569,"d":"2.36"},{"v":9.36935432234845,"d":"9.37"},{"v":3.22794962973694,"d":"3.23"},{"v":0.000871567185946492,"d":"0.00"},{"v":0.0604275493615192,"d":"0.06"},"up","yes"]
[62359,0,"chr15","+",32718004,32745106,"ENST00000651154",2,14575,"ENSG00000166923","GREM1","GO:0000902(cell morphogenesis);GO:0001525(angiogenesis);GO:0001658(branching involved in ureteric bud morphogenesis);GO:0002042(cell migration involved in sprouting angiogenesis);GO:0002092(positive regulation of receptor internalization);GO:0002689(negative regulation of leukocyte chemotaxis);GO:0003257(positive regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation);GO:0003337(mesenchymal to epithelial transition involved in metanephros morphogenesis);GO:0005125(cytokine activity);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0005615(extracellular space);GO:0006915(apoptotic process);GO:0007165(signal transduction);GO:0007171(activation of transmembrane receptor protein tyrosine kinase activity);GO:0007267(cell-cell signaling);GO:0008284(positive regulation of cell population proliferation);GO:0009887(animal organ morphogenesis);GO:0009954(proximal/distal pattern formation);GO:0009986(cell surface);GO:0010717(regulation of epithelial to mesenchymal transition);GO:0016015(morphogen activity);GO:0030199(collagen fibril organization);GO:0030297(transmembrane receptor protein tyrosine kinase activator activity);GO:0030308(negative regulation of cell growth);GO:0030326(embryonic limb morphogenesis);GO:0030502(negative regulation of bone mineralization);GO:0030514(negative regulation of BMP signaling pathway);GO:0032331(negative regulation of chondrocyte differentiation);GO:0033689(negative regulation of osteoblast proliferation);GO:0036122(BMP binding);GO:0042803(protein homodimerization activity);GO:0043066(negative regulation of apoptotic process);GO:0043184(vascular endothelial growth factor receptor 2 binding);GO:0043542(endothelial cell migration);GO:0045668(negative regulation of osteoblast differentiation);GO:0045766(positive regulation of angiogenesis);GO:0045892(negative regulation of transcription, DNA-templated);GO:0045893(positive regulation of transcription, DNA-templated);GO:0045944(positive regulation of transcription by RNA polymerase II);GO:0046851(negative regulation of bone remodeling);GO:0048018(receptor ligand activity);GO:0048263(determination of dorsal identity);GO:0051092(positive regulation of NF-kappaB transcription factor activity);GO:0051893(regulation of focal adhesion assembly);GO:0051973(positive regulation of telomerase activity);GO:0060173(limb development);GO:0060394(negative regulation of pathway-restricted SMAD protein phosphorylation);GO:0060676(ureteric bud formation);GO:0061098(positive regulation of protein tyrosine kinase activity);GO:0062023(collagen-containing extracellular matrix);GO:0090027(negative regulation of monocyte chemotaxis);GO:0090090(negative regulation of canonical Wnt signaling pathway);GO:0090190(positive regulation of branching involved in ureteric bud morphogenesis);GO:0090291(negative regulation of osteoclast proliferation);GO:1900086(positive regulation of peptidyl-tyrosine autophosphorylation);GO:1900155(negative regulation of bone trabecula formation);GO:1900158(negative regulation of bone mineralization involved in bone maturation);GO:1901224(positive regulation of NIK/NF-kappaB signaling);GO:2000273(positive regulation of signaling receptor activity);GO:2000727(positive regulation of cardiac muscle cell differentiation)","04350(TGF-beta signaling pathway)","NA","NA","gremlin 1, DAN family BMP antagonist [Source:HGNC Symbol;Acc:HGNC:2001]",{"v":0.447313,"d":"0.45"},{"v":0.757326,"d":"0.76"},{"v":0.499904,"d":"0.50"},{"v":0.442896,"d":"0.44"},{"v":0.875284,"d":"0.88"},{"v":30.68671,"d":"30.69"},{"v":0.05325883013502,"d":"0.05"},{"v":-4.23083545061676,"d":"-4.23"},{"v":0.000875480355998987,"d":"0.00"},{"v":0.0605832406351299,"d":"0.06"},"down","yes"]
[28353,0,"chr11","+",20387716,20508708,"ENST00000437750",14,1736,"ENSG00000185238","PRMT3","GO:0003676(nucleic acid binding);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0006355(regulation of transcription, DNA-templated);GO:0006479(protein methylation);GO:0008168(methyltransferase activity);GO:0008469(histone-arginine N-methyltransferase activity);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016274(protein-arginine N-methyltransferase activity);GO:0016740(transferase activity);GO:0019919(peptidyl-arginine methylation, to asymmetrical-dimethyl arginine);GO:0031397(negative regulation of protein ubiquitination);GO:0032259(methylation);GO:0034969(histone arginine methylation);GO:0035242(protein-arginine omega-N asymmetric methyltransferase activity);GO:0043022(ribosome binding);GO:0046872(metal ion binding)","NA","K11436","EC:2.1.1.319","protein arginine methyltransferase 3 [Source:HGNC Symbol;Acc:HGNC:30163]",0,0,0,0,{"v":1.200593,"d":"1.20"},{"v":0.563625,"d":"0.56"},"-inf","-inf",{"v":0.000886471825517558,"d":"0.00"},{"v":0.0611990541103105,"d":"0.06"},"down","yes"]
[202658,0,"chrX","-",46499437,46544611,"ENST00000414387",5,2274,"ENSG00000251192","ZNF674","GO:0000981(DNA-binding transcription factor activity, RNA polymerase II-specific);GO:0003676(nucleic acid binding);GO:0003677(DNA binding);GO:0005622(intracellular);GO:0005634(nucleus);GO:0006355(regulation of transcription, DNA-templated);GO:0006357(regulation of transcription by RNA polymerase II);GO:0045892(negative regulation of transcription, DNA-templated);GO:0046872(metal ion binding)","05168(Herpes simplex virus 1 infection)","K09228","NA","zinc finger protein 674 [Source:HGNC Symbol;Acc:HGNC:17625]",0,{"v":0.986457,"d":"0.99"},{"v":0.403022,"d":"0.40"},0,0,0,"inf","inf",{"v":0.000887748459018266,"d":"0.00"},{"v":0.0611990541103105,"d":"0.06"},"up","yes"]
[76618,0,"chr16","-",67944485,67968553,"ENST00000576616",23,3768,"ENSG00000124067","SLC12A4","GO:0005215(transporter activity);GO:0005765(lysosomal membrane);GO:0005886(plasma membrane);GO:0005887(integral component of plasma membrane);GO:0006811(ion transport);GO:0006813(potassium ion transport);GO:0006884(cell volume homeostasis);GO:0007268(chemical synaptic transmission);GO:0015293(symporter activity);GO:0015377(cation:chloride symporter activity);GO:0015379(potassium:chloride symporter activity);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0019901(protein kinase binding);GO:0055064(chloride ion homeostasis);GO:0055075(potassium ion homeostasis);GO:0055085(transmembrane transport);GO:0071477(cellular hypotonic salinity response);GO:0071805(potassium ion transmembrane transport);GO:1902476(chloride transmembrane transport);GO:1990573(potassium ion import across plasma membrane)","NA","K14427","NA","solute carrier family 12 member 4 [Source:HGNC Symbol;Acc:HGNC:10913]",{"v":0.344545,"d":"0.34"},{"v":0.336237,"d":"0.34"},{"v":0.182998,"d":"0.18"},{"v":7.037783,"d":"7.04"},{"v":0.433103,"d":"0.43"},{"v":4.727206,"d":"4.73"},{"v":0.0708127139883844,"d":"0.07"},{"v":-3.81984777916617,"d":"-3.82"},{"v":0.000939488518546138,"d":"0.00"},{"v":0.0646167606871365,"d":"0.06"},"down","yes"]
[195502,0,"chr9","-",35099776,35103195,"ENST00000619795",9,1293,"ENSG00000165283","STOML2","GO:0001772(immunological synapse);GO:0005102(signaling receptor binding);GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0005739(mitochondrion);GO:0005743(mitochondrial inner membrane);GO:0005758(mitochondrial intermembrane space);GO:0005856(cytoskeleton);GO:0005886(plasma membrane);GO:0006851(mitochondrial calcium ion transmembrane transport);GO:0006874(cellular calcium ion homeostasis);GO:0007005(mitochondrion organization);GO:0008180(COP9 signalosome);GO:0008289(lipid binding);GO:0010876(lipid localization);GO:0010918(positive regulation of mitochondrial membrane potential);GO:0015629(actin cytoskeleton);GO:0016020(membrane);GO:0019897(extrinsic component of plasma membrane);GO:0032623(interleukin-2 production);GO:0034982(mitochondrial protein processing);GO:0035710(CD4-positive, alpha-beta T cell activation);GO:0042101(T cell receptor complex);GO:0042776(mitochondrial ATP synthesis coupled proton transport);GO:0045121(membrane raft);GO:0050852(T cell receptor signaling pathway);GO:0051020(GTPase binding);GO:0051259(protein complex oligomerization);GO:0090297(positive regulation of mitochondrial DNA replication);GO:1900210(positive regulation of cardiolipin metabolic process);GO:1901612(cardiolipin binding);GO:1990046(stress-induced mitochondrial fusion)","NA","NA","NA","stomatin like 2 [Source:HGNC Symbol;Acc:HGNC:14559]",{"v":1.221765,"d":"1.22"},0,{"v":0.980973,"d":"0.98"},0,0,0,"inf","inf",{"v":0.000940882642540469,"d":"0.00"},{"v":0.0646167606871365,"d":"0.06"},"up","yes"]
[49061,0,"chr12","-",121799172,121802946,"ENST00000535643",4,1014,"ENSG00000212694","LINC01089","NA","NA","NA","NA","long intergenic non-protein coding RNA 1089 [Source:HGNC Symbol;Acc:HGNC:27886]",{"v":1.802184,"d":"1.80"},{"v":1.031344,"d":"1.03"},0,0,0,0,"inf","inf",{"v":0.000955670590959785,"d":"0.00"},{"v":0.0654831921084086,"d":"0.07"},"up","yes"]
[166428,0,"chr5","-",179836634,179858806,"ENST00000518235",8,1244,"ENSG00000161010","MRNIP","GO:0003682(chromatin binding);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0006281(DNA repair);GO:0006974(cellular response to DNA damage stimulus);GO:0007095(mitotic G2 DNA damage checkpoint);GO:0010212(response to ionizing radiation);GO:0030870(Mre11 complex);GO:0045860(positive regulation of protein kinase activity);GO:0071168(protein localization to chromatin);GO:1905168(positive regulation of double-strand break repair via homologous recombination);GO:2001032(regulation of double-strand break repair via nonhomologous end joining)","NA","NA","NA","MRN complex interacting protein [Source:HGNC Symbol;Acc:HGNC:30817]",{"v":9.091286,"d":"9.09"},{"v":5.889644,"d":"5.89"},{"v":0.03386,"d":"0.03"},{"v":0.123789,"d":"0.12"},{"v":0.036801,"d":"0.04"},{"v":0.181595,"d":"0.18"},{"v":43.8791589344945,"d":"43.88"},{"v":5.45546396765074,"d":"5.46"},{"v":0.000957103633624139,"d":"0.00"},{"v":0.0654831921084086,"d":"0.07"},"up","yes"]
[60836,0,"chr14","+",103629241,103701544,"ENST00000554280",16,2426,"ENSG00000126214","KLC1","GO:0003774(motor activity);GO:0003777(microtubule motor activity);GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005856(cytoskeleton);GO:0005871(kinesin complex);GO:0005874(microtubule);GO:0006890(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum);GO:0007018(microtubule-based movement);GO:0016020(membrane);GO:0016032(viral process);GO:0019886(antigen processing and presentation of exogenous peptide antigen via MHC class II);GO:0030426(growth cone);GO:0031410(cytoplasmic vesicle);GO:0035617(stress granule disassembly);GO:0042995(cell projection)","05132(Salmonella infection)","K10407","NA","kinesin light chain 1 [Source:HGNC Symbol;Acc:HGNC:6387]",{"v":13.369243,"d":"13.37"},{"v":0.954521,"d":"0.95"},{"v":6.767603,"d":"6.77"},{"v":0.383046,"d":"0.38"},{"v":0.783556,"d":"0.78"},{"v":0.407183,"d":"0.41"},{"v":13.4016825678222,"d":"13.40"},{"v":3.7443422358589,"d":"3.74"},{"v":0.000961697302663772,"d":"0.00"},{"v":0.0656111622397199,"d":"0.07"},"up","yes"]
[27052,0,"chr11","-",6612832,6618891,"ENST00000643516",9,2915,"ENSG00000166340","TPP1","GO:0004175(endopeptidase activity);GO:0004252(serine-type endopeptidase activity);GO:0005515(protein binding);GO:0005764(lysosome);GO:0006508(proteolysis);GO:0006629(lipid metabolic process);GO:0007040(lysosome organization);GO:0007399(nervous system development);GO:0007417(central nervous system development);GO:0008233(peptidase activity);GO:0008236(serine-type peptidase activity);GO:0008240(tripeptidyl-peptidase activity);GO:0016787(hydrolase activity);GO:0030163(protein catabolic process);GO:0030855(epithelial cell differentiation);GO:0036498(IRE1-mediated unfolded protein response);GO:0042277(peptide binding);GO:0042470(melanosome);GO:0043171(peptide catabolic process);GO:0043202(lysosomal lumen);GO:0045453(bone resorption);GO:0046872(metal ion binding);GO:0050885(neuromuscular process controlling balance);GO:0070062(extracellular exosome)","04142(Lysosome)","NA","NA","tripeptidyl peptidase 1 [Source:HGNC Symbol;Acc:HGNC:2073]",0,0,0,0,{"v":0.692554,"d":"0.69"},{"v":0.31077,"d":"0.31"},"-inf","-inf",{"v":0.00096301409104003,"d":"0.00"},{"v":0.0656111622397199,"d":"0.07"},"down","yes"]
[96343,0,"chr19","+",797462,805017,"ENST00000589575",8,749,"ENSG00000011304","PTBP1","GO:0000381(regulation of alternative mRNA splicing, via spliceosome);GO:0000398(mRNA splicing, via spliceosome);GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005730(nucleolus);GO:0006397(mRNA processing);GO:0008187(poly-pyrimidine tract binding);GO:0008380(RNA splicing);GO:0008543(fibroblast growth factor receptor signaling pathway);GO:0016020(membrane);GO:0016070(RNA metabolic process);GO:0033119(negative regulation of RNA splicing);GO:0035307(positive regulation of protein dephosphorylation);GO:0036002(pre-mRNA binding);GO:0048025(negative regulation of mRNA splicing, via spliceosome);GO:0051148(negative regulation of muscle cell differentiation);GO:0070062(extracellular exosome);GO:0070886(positive regulation of calcineurin-NFAT signaling cascade);GO:0075522(IRES-dependent viral translational initiation)","NA","K13218","NA","polypyrimidine tract binding protein 1 [Source:HGNC Symbol;Acc:HGNC:9583]",0,0,0,{"v":1.937207,"d":"1.94"},{"v":1.749845,"d":"1.75"},0,"-inf","-inf",{"v":0.000966904961101073,"d":"0.00"},{"v":0.0656111622397199,"d":"0.07"},"down","yes"]
[47930,0,"chr12","-",110491624,110499546,"ENST00000552130",5,1057,"ENSG00000111237","VPS29","GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0005768(endosome);GO:0005769(early endosome);GO:0005770(late endosome);GO:0005829(cytosol);GO:0006886(intracellular protein transport);GO:0008565(protein transporter activity);GO:0010008(endosome membrane);GO:0015031(protein transport);GO:0016020(membrane);GO:0016032(viral process);GO:0016055(Wnt signaling pathway);GO:0030904(retromer complex);GO:0030906(retromer, cargo-selective complex);GO:0032456(endocytic recycling);GO:0042147(retrograde transport, endosome to Golgi);GO:0043231(intracellular membrane-bounded organelle);GO:0046872(metal ion binding);GO:1990126(retrograde transport, endosome to plasma membrane)","04144(Endocytosis)","K18467","NA","VPS29, retromer complex component [Source:HGNC Symbol;Acc:HGNC:14340]",{"v":0.358036,"d":"0.36"},{"v":11.713339,"d":"11.71"},{"v":11.919806,"d":"11.92"},{"v":0.208851,"d":"0.21"},0,{"v":0.323097,"d":"0.32"},{"v":45.1006132178333,"d":"45.10"},{"v":5.49507514433948,"d":"5.50"},{"v":0.000966994897148778,"d":"0.00"},{"v":0.0656111622397199,"d":"0.07"},"up","yes"]
[139108,0,"chr3","+",45689355,45743935,"ENST00000441228",19,2013,"ENSG00000211456","SACM1L","GO:0000139(Golgi membrane);GO:0004438(phosphatidylinositol-3-phosphatase activity);GO:0005515(protein binding);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005794(Golgi apparatus);GO:0006661(phosphatidylinositol biosynthetic process);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016787(hydrolase activity);GO:0016791(phosphatase activity);GO:0030176(integral component of endoplasmic reticulum membrane);GO:0032281(AMPA glutamate receptor complex);GO:0034593(phosphatidylinositol bisphosphate phosphatase activity);GO:0034596(phosphatidylinositol phosphate 4-phosphatase activity);GO:0042578(phosphoric ester hydrolase activity);GO:0043812(phosphatidylinositol-4-phosphate phosphatase activity);GO:0046856(phosphatidylinositol dephosphorylation)","00562(Inositol phosphate metabolism);04070(Phosphatidylinositol signaling system)","K21797","EC:3.1.3.-","SAC1 like phosphatidylinositide phosphatase [Source:HGNC Symbol;Acc:HGNC:17059]",{"v":0.778604,"d":"0.78"},{"v":0.604724,"d":"0.60"},0,0,0,0,"inf","inf",{"v":0.000969494059208564,"d":"0.00"},{"v":0.0656111622397199,"d":"0.07"},"up","yes"]
[206206,0,"chrX","-",134544426,134545738,"ENST00000457876",2,646,"ENSG00000223749","MIR503HG","NA","NA","NA","NA","MIR503 host gene [Source:HGNC Symbol;Acc:HGNC:28258]",0,0,0,0,{"v":1.842265,"d":"1.84"},{"v":2.449383,"d":"2.45"},"-inf","-inf",{"v":0.000969809912544167,"d":"0.00"},{"v":0.0656111622397199,"d":"0.07"},"down","yes"]
[103804,0,"chr19","-",39825350,39833634,"ENST00000593685",11,2724,"ENSG00000105204","DYRK1B","GO:0000166(nucleotide binding);GO:0003713(transcription coactivator activity);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0004712(protein serine/threonine/tyrosine kinase activity);GO:0004713(protein tyrosine kinase activity);GO:0005515(protein binding);GO:0005524(ATP binding);GO:0005634(nucleus);GO:0006468(protein phosphorylation);GO:0007520(myoblast fusion);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0016740(transferase activity);GO:0018108(peptidyl-tyrosine phosphorylation);GO:0045893(positive regulation of transcription, DNA-templated);GO:0060612(adipose tissue development)","NA","K08825","EC:2.7.12.1","dual specificity tyrosine phosphorylation regulated kinase 1B [Source:HGNC Symbol;Acc:HGNC:3092]",0,{"v":0.007906,"d":"0.01"},0,{"v":0.016461,"d":"0.02"},{"v":0.36533,"d":"0.37"},{"v":0.775885,"d":"0.78"},{"v":0.00682919918871947,"d":"0.01"},{"v":-7.19406787074392,"d":"-7.19"},{"v":0.000974393500859859,"d":"0.00"},{"v":0.0656883335628519,"d":"0.07"},"down","yes"]
[54550,0,"chr14","-",22773316,22780475,"ENST00000554061",9,1501,"ENSG00000155465","SLC7A7","GO:0000821(regulation of arginine metabolic process);GO:0005886(plasma membrane);GO:0005887(integral component of plasma membrane);GO:0006520(cellular amino acid metabolic process);GO:0006865(amino acid transport);GO:0015174(basic amino acid transmembrane transporter activity);GO:0015179(L-amino acid transmembrane transporter activity);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016323(basolateral plasma membrane);GO:0022857(transmembrane transporter activity);GO:0050900(leukocyte migration);GO:0055085(transmembrane transport);GO:0065003(protein-containing complex assembly);GO:1902475(L-alpha-amino acid transmembrane transport);GO:1990822(basic amino acid transmembrane transport)","04974(Protein digestion and absorption)","K13867","NA","solute carrier family 7 member 7 [Source:HGNC Symbol;Acc:HGNC:11065]",{"v":0.799104,"d":"0.80"},{"v":1.046513,"d":"1.05"},0,0,0,0,"inf","inf",{"v":0.000974566798524007,"d":"0.00"},{"v":0.0656883335628519,"d":"0.07"},"up","yes"]
[157775,0,"chr5","+",17065598,17275353,"ENST00000606445",4,401,"ENSG00000176788","BASP1","GO:0003714(transcription corepressor activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005856(cytoskeleton);GO:0005886(plasma membrane);GO:0007356(thorax and anterior abdomen determination);GO:0008180(COP9 signalosome);GO:0008406(gonad development);GO:0016020(membrane);GO:0016607(nuclear speck);GO:0019904(protein domain specific binding);GO:0021762(substantia nigra development);GO:0030054(cell junction);GO:0030426(growth cone);GO:0031982(vesicle);GO:0042995(cell projection);GO:0044212(transcription regulatory region DNA binding);GO:0045892(negative regulation of transcription, DNA-templated);GO:0060231(mesenchymal to epithelial transition);GO:0060421(positive regulation of heart growth);GO:0060539(diaphragm development);GO:0070062(extracellular exosome);GO:0072075(metanephric mesenchyme development);GO:0072112(glomerular visceral epithelial cell differentiation);GO:2001076(positive regulation of metanephric ureteric bud development)","NA","K17272","NA","brain abundant membrane attached signal protein 1 [Source:HGNC Symbol;Acc:HGNC:957]",0,{"v":3.118518,"d":"3.12"},{"v":3.869583,"d":"3.87"},0,0,0,"inf","inf",{"v":0.000979161194362614,"d":"0.00"},{"v":0.0658757892429514,"d":"0.07"},"up","yes"]
[43272,0,"chr12","+",53006456,53040280,"ENST00000420463",15,1936,"ENSG00000063046","EIF4B","GO:0001731(formation of translation preinitiation complex);GO:0002181(cytoplasmic translation);GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0003743(translation initiation factor activity);GO:0005515(protein binding);GO:0005829(cytosol);GO:0005844(polysome);GO:0006412(translation);GO:0006413(translational initiation);GO:0006446(regulation of translational initiation);GO:0016281(eukaryotic translation initiation factor 4F complex);GO:0030425(dendrite);GO:0033592(RNA strand annealing activity);GO:0034057(RNA strand-exchange activity);GO:0043024(ribosomal small subunit binding);GO:0043025(neuronal cell body);GO:0097010(eukaryotic translation initiation factor 4F complex assembly);GO:0098794(postsynapse)","03013(RNA transport);04150(mTOR signaling pathway);04151(PI3K-Akt signaling pathway);05205(Proteoglycans in cancer)","K03258","NA","eukaryotic translation initiation factor 4B [Source:HGNC Symbol;Acc:HGNC:3285]",{"v":10.039068,"d":"10.04"},{"v":10.915519,"d":"10.92"},{"v":11.938098,"d":"11.94"},{"v":30.546017,"d":"30.55"},{"v":66.202835,"d":"66.20"},{"v":60.618141,"d":"60.62"},{"v":0.209018958632577,"d":"0.21"},{"v":-2.25829428997484,"d":"-2.26"},{"v":0.00100160636231798,"d":"0.00"},{"v":0.0672612923161039,"d":"0.07"},"down","yes"]
[126155,0,"chr20","+",34445361,34481176,"ENST00000483727",10,1070,"ENSG00000078747","ITCH","GO:0000209(protein polyubiquitination);GO:0001558(regulation of cell growth);GO:0002376(immune system process);GO:0002669(positive regulation of T cell anergy);GO:0004842(ubiquitin-protein transferase activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0005768(endosome);GO:0005769(early endosome);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0005938(cell cortex);GO:0006511(ubiquitin-dependent protein catabolic process);GO:0006915(apoptotic process);GO:0006954(inflammatory response);GO:0007219(Notch signaling pathway);GO:0010008(endosome membrane);GO:0016020(membrane);GO:0016032(viral process);GO:0016567(protein ubiquitination);GO:0016740(transferase activity);GO:0016874(ligase activity);GO:0031410(cytoplasmic vesicle);GO:0031901(early endosome membrane);GO:0032088(negative regulation of NF-kappaB transcription factor activity);GO:0032480(negative regulation of type I interferon production);GO:0032991(protein-containing complex);GO:0035519(protein K29-linked ubiquitination);GO:0043021(ribonucleoprotein complex binding);GO:0043066(negative regulation of apoptotic process);GO:0043161(proteasome-mediated ubiquitin-dependent protein catabolic process);GO:0043231(intracellular membrane-bounded organelle);GO:0044389(ubiquitin-like protein ligase binding);GO:0045087(innate immune response);GO:0045236(CXCR chemokine receptor binding);GO:0045732(positive regulation of protein catabolic process);GO:0046329(negative regulation of JNK cascade);GO:0046642(negative regulation of alpha-beta T cell proliferation);GO:0046718(viral entry into host cell);GO:0050687(negative regulation of defense response to virus);GO:0051607(defense response to virus);GO:0051865(protein autoubiquitination);GO:0061630(ubiquitin protein ligase activity);GO:0070062(extracellular exosome);GO:0070423(nucleotide-binding oligomerization domain containing signaling pathway);GO:0070534(protein K63-linked ubiquitination);GO:0070936(protein K48-linked ubiquitination);GO:0090085(regulation of protein deubiquitination);GO:1902036(regulation of hematopoietic stem cell differentiation);GO:1990763(arrestin family protein binding);GO:2000646(positive regulation of receptor catabolic process)","04120(Ubiquitin mediated proteolysis);04144(Endocytosis);04668(TNF signaling pathway);04932(Non-alcoholic fatty liver disease (NAFLD))","K05632","EC:2.3.2.26","itchy E3 ubiquitin protein ligase [Source:HGNC Symbol;Acc:HGNC:13890]",{"v":5.623538,"d":"5.62"},{"v":3.013018,"d":"3.01"},{"v":0.118266,"d":"0.12"},0,{"v":0.109556,"d":"0.11"},{"v":0.078507,"d":"0.08"},{"v":46.5526020535672,"d":"46.55"},{"v":5.54078990423667,"d":"5.54"},{"v":0.00100741707250601,"d":"0.00"},{"v":0.0675266831072754,"d":"0.07"},"up","yes"]
[3669,0,"chr1","-",30932059,31065726,"ENST00000525843",21,4528,"ENSG00000134644","PUM1","GO:0000932(P-body);GO:0003723(RNA binding);GO:0003730(mRNA 3'-UTR binding);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0006417(regulation of translation);GO:0007283(spermatogenesis);GO:0008344(adult locomotory behavior);GO:0010494(cytoplasmic stress granule);GO:0010608(posttranscriptional regulation of gene expression);GO:0016441(posttranscriptional gene silencing);GO:0016607(nuclear speck);GO:0030154(cell differentiation);GO:0035196(production of miRNAs involved in gene silencing by miRNA);GO:0035198(miRNA binding);GO:0043488(regulation of mRNA stability);GO:0048863(stem cell differentiation);GO:0051726(regulation of cell cycle);GO:0051983(regulation of chromosome segregation);GO:0060964(regulation of gene silencing by miRNA);GO:0061157(mRNA destabilization);GO:1900246(positive regulation of RIG-I signaling pathway);GO:2000637(positive regulation of gene silencing by miRNA)","NA","K17943","NA","pumilio RNA binding family member 1 [Source:HGNC Symbol;Acc:HGNC:14957]",{"v":5.73384,"d":"5.73"},{"v":0.577836,"d":"0.58"},{"v":5.504792,"d":"5.50"},{"v":0.198685,"d":"0.20"},{"v":0.51452,"d":"0.51"},{"v":0.214094,"d":"0.21"},{"v":12.7428887554068,"d":"12.74"},{"v":3.67162046201665,"d":"3.67"},{"v":0.00101844517761195,"d":"0.00"},{"v":0.0680172524055856,"d":"0.07"},"up","yes"]
[57512,0,"chr14","+",64465499,64474503,"ENST00000394718",2,6487,"ENSG00000179841","AKAP5","GO:0005515(protein binding);GO:0005516(calmodulin binding);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0006605(protein targeting);GO:0007165(signal transduction);GO:0007193(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway);GO:0007194(negative regulation of adenylate cyclase activity);GO:0007268(chemical synaptic transmission);GO:0008179(adenylate cyclase binding);GO:0009898(cytoplasmic side of plasma membrane);GO:0010738(regulation of protein kinase A signaling);GO:0014069(postsynaptic density);GO:0016020(membrane);GO:0017124(SH3 domain binding);GO:0030346(protein phosphatase 2B binding);GO:0031698(beta-2 adrenergic receptor binding);GO:0032590(dendrite membrane);GO:0032947(protein-containing complex scaffold activity);GO:0034237(protein kinase A regulatory subunit binding);GO:0035254(glutamate receptor binding);GO:0043197(dendritic spine);GO:0045121(membrane raft);GO:0045762(positive regulation of adenylate cyclase activity);GO:0050811(GABA receptor binding);GO:0051018(protein kinase A binding);GO:0060076(excitatory synapse);GO:0097110(scaffold protein binding);GO:1903078(positive regulation of protein localization to plasma membrane)","NA","K16522","NA","A-kinase anchoring protein 5 [Source:HGNC Symbol;Acc:HGNC:375]",0,0,0,{"v":0.185461,"d":"0.19"},{"v":0.221298,"d":"0.22"},0,"-inf","-inf",{"v":0.00102011901926074,"d":"0.00"},{"v":0.0680172524055856,"d":"0.07"},"down","yes"]
[55773,0,"chr14","+",32939243,33804176,"ENST00000346562",11,5847,"ENSG00000151322","NPAS3","GO:0000981(DNA-binding transcription factor activity, RNA polymerase II-specific);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0006355(regulation of transcription, DNA-templated);GO:0006357(regulation of transcription by RNA polymerase II);GO:0045893(positive regulation of transcription, DNA-templated);GO:0045944(positive regulation of transcription by RNA polymerase II);GO:0046982(protein heterodimerization activity);GO:0046983(protein dimerization activity)","NA","K09098","NA","neuronal PAS domain protein 3 [Source:HGNC Symbol;Acc:HGNC:19311]",0,0,0,0,{"v":0.171972,"d":"0.17"},{"v":0.294715,"d":"0.29"},"-inf","-inf",{"v":0.00102035239639538,"d":"0.00"},{"v":0.0680172524055856,"d":"0.07"},"down","yes"]
[193648,0,"chr8","-",143915153,143942524,"ENST00000357649",32,14689,"ENSG00000178209","PLEC","GO:0003723(RNA binding);GO:0003779(actin binding);GO:0005198(structural molecule activity);GO:0005200(structural constituent of cytoskeleton);GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005856(cytoskeleton);GO:0005882(intermediate filament);GO:0005886(plasma membrane);GO:0005903(brush border);GO:0005925(focal adhesion);GO:0007010(cytoskeleton organization);GO:0008092(cytoskeletal protein binding);GO:0008307(structural constituent of muscle);GO:0016020(membrane);GO:0016528(sarcoplasm);GO:0030054(cell junction);GO:0030056(hemidesmosome);GO:0030506(ankyrin binding);GO:0031581(hemidesmosome assembly);GO:0042060(wound healing);GO:0042383(sarcolemma);GO:0043034(costamere);GO:0043292(contractile fiber);GO:0045104(intermediate filament cytoskeleton organization);GO:0045111(intermediate filament cytoskeleton);GO:0045296(cadherin binding);GO:0048471(perinuclear region of cytoplasm);GO:0070062(extracellular exosome)","NA","K10388","NA","plectin [Source:HGNC Symbol;Acc:HGNC:9069]",{"v":0.113491,"d":"0.11"},{"v":0.386847,"d":"0.39"},{"v":0.457145,"d":"0.46"},{"v":1.107679,"d":"1.11"},{"v":9.900531,"d":"9.90"},{"v":0.507338,"d":"0.51"},{"v":0.0831469765919954,"d":"0.08"},{"v":-3.58819238489161,"d":"-3.59"},{"v":0.00102227795726359,"d":"0.00"},{"v":0.0680208025410001,"d":"0.07"},"down","yes"]
[160088,0,"chr5","-",75372598,75511620,"ENST00000645866",16,3720,"ENSG00000113163","COL4A3BP","GO:0000902(cell morphogenesis);GO:0001701(in utero embryonic development);GO:0003007(heart morphogenesis);GO:0005515(protein binding);GO:0005581(collagen trimer);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0005739(mitochondrion);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005794(Golgi apparatus);GO:0005829(cytosol);GO:0006672(ceramide metabolic process);GO:0006869(lipid transport);GO:0006936(muscle contraction);GO:0006955(immune response);GO:0007029(endoplasmic reticulum organization);GO:0007165(signal transduction);GO:0008283(cell population proliferation);GO:0008289(lipid binding);GO:0016020(membrane);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0030148(sphingolipid biosynthetic process);GO:0034976(response to endoplasmic reticulum stress);GO:0035621(ER to Golgi ceramide transport);GO:0035627(ceramide transport);GO:0048471(perinuclear region of cytoplasm);GO:0055088(lipid homeostasis);GO:0070273(phosphatidylinositol-4-phosphate binding);GO:0070584(mitochondrion morphogenesis);GO:0097001(ceramide binding);GO:0120009(intermembrane lipid transfer);GO:0120012(intermembrane sphingolipid transfer);GO:0120017(intermembrane ceramide transfer activity);GO:1902387(ceramide 1-phosphate binding);GO:1902388(ceramide 1-phosphate transporter activity);GO:1902389(ceramide 1-phosphate transport)","NA","K08283","NA","collagen type IV alpha 3 binding protein [Source:HGNC Symbol;Acc:HGNC:2205]",0,{"v":0.32008,"d":"0.32"},{"v":0.407773,"d":"0.41"},0,0,0,"inf","inf",{"v":0.00103673797203785,"d":"0.00"},{"v":0.0688568382525319,"d":"0.07"},"up","yes"]
[201755,0,"chrX","+",16946862,17153272,"ENST00000303843",18,7771,"ENSG00000169891","REPS2","GO:0005509(calcium ion binding);GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0007173(epidermal growth factor receptor signaling pathway);GO:0046872(metal ion binding);GO:0061024(membrane organization);GO:0065003(protein-containing complex assembly)","NA","K20068","NA","RALBP1 associated Eps domain containing 2 [Source:HGNC Symbol;Acc:HGNC:9963]",0,0,0,{"v":0.214,"d":"0.21"},0,{"v":0.110562,"d":"0.11"},"-inf","-inf",{"v":0.00103911262284349,"d":"0.00"},{"v":0.0688886160363213,"d":"0.07"},"down","yes"]
[163519,0,"chr5","-",140632344,140633651,"ENST00000498971",3,882,"ENSG00000170458","CD14","GO:0001530(lipopolysaccharide binding);GO:0001847(opsonin receptor activity);GO:0002224(toll-like receptor signaling pathway);GO:0002237(response to molecule of bacterial origin);GO:0002376(immune system process);GO:0002755(MyD88-dependent toll-like receptor signaling pathway);GO:0002756(MyD88-independent toll-like receptor signaling pathway);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0005615(extracellular space);GO:0005794(Golgi apparatus);GO:0005886(plasma membrane);GO:0006898(receptor-mediated endocytosis);GO:0006909(phagocytosis);GO:0006915(apoptotic process);GO:0006954(inflammatory response);GO:0007166(cell surface receptor signaling pathway);GO:0007249(I-kappaB kinase/NF-kappaB signaling);GO:0009408(response to heat);GO:0009617(response to bacterium);GO:0009897(external side of plasma membrane);GO:0009986(cell surface);GO:0010008(endosome membrane);GO:0016019(peptidoglycan receptor activity);GO:0016020(membrane);GO:0030667(secretory granule membrane);GO:0031225(anchored component of membrane);GO:0031362(anchored component of external side of plasma membrane);GO:0031663(lipopolysaccharide-mediated signaling pathway);GO:0032026(response to magnesium ion);GO:0032481(positive regulation of type I interferon production);GO:0032496(response to lipopolysaccharide);GO:0032729(positive regulation of interferon-gamma production);GO:0032760(positive regulation of tumor necrosis factor production);GO:0034128(negative regulation of MyD88-independent toll-like receptor signaling pathway);GO:0034142(toll-like receptor 4 signaling pathway);GO:0034612(response to tumor necrosis factor);GO:0035666(TRIF-dependent toll-like receptor signaling pathway);GO:0038123(toll-like receptor TLR1:TLR2 signaling pathway);GO:0038124(toll-like receptor TLR6:TLR2 signaling pathway);GO:0043312(neutrophil degranulation);GO:0045087(innate immune response);GO:0045121(membrane raft);GO:0045471(response to ethanol);GO:0045807(positive regulation of endocytosis);GO:0046696(lipopolysaccharide receptor complex);GO:0050715(positive regulation of cytokine secretion);GO:0051602(response to electrical stimulus);GO:0070062(extracellular exosome);GO:0070266(necroptotic process);GO:0070891(lipoteichoic acid binding);GO:0071219(cellular response to molecule of bacterial origin);GO:0071222(cellular response to lipopolysaccharide);GO:0071223(cellular response to lipoteichoic acid);GO:0071723(lipopeptide binding);GO:0071726(cellular response to diacyl bacterial lipopeptide);GO:0071727(cellular response to triacyl bacterial lipopeptide);GO:0097190(apoptotic signaling pathway);GO:1901224(positive regulation of NIK/NF-kappaB signaling);GO:2000484(positive regulation of interleukin-8 secretion)","04010(MAPK signaling pathway);04064(NF-kappa B signaling pathway);04145(Phagosome);04620(Toll-like receptor signaling pathway);04640(Hematopoietic cell lineage);05130(Pathogenic Escherichia coli infection);05132(Salmonella infection);05133(Pertussis);05134(Legionellosis);05146(Amoebiasis);05152(Tuberculosis);05202(Transcriptional misregulation in cancer);05221(Acute myeloid leukemia)","NA","NA","CD14 molecule [Source:HGNC Symbol;Acc:HGNC:1628]",0,0,0,0,{"v":1.505626,"d":"1.51"},{"v":1.424026,"d":"1.42"},"-inf","-inf",{"v":0.00106693785784449,"d":"0.00"},{"v":0.0706044669863209,"d":"0.07"},"down","yes"]
[33464,0,"chr11","-",69653076,69658430,"ENST00000542515",3,2299,"ENSG00000149716","LTO1","GO:0000723(telomere maintenance);GO:0003674(molecular_function);GO:0005515(protein binding);GO:0005575(cellular_component);GO:0005634(nucleus);GO:0006413(translational initiation);GO:0042273(ribosomal large subunit biogenesis);GO:0106035(protein maturation by [4Fe-4S] cluster transfer)","NA","NA","NA","LTO1, ABCE1 maturation factor [Source:HGNC Symbol;Acc:HGNC:17589]",{"v":0.483234,"d":"0.48"},{"v":0.647499,"d":"0.65"},0,0,0,0,"inf","inf",{"v":0.00107610825009224,"d":"0.00"},{"v":0.0710818413197293,"d":"0.07"},"up","yes"]
[23242,0,"chr10","-",95311773,95339327,"ENST00000649911",4,3853,"ENSG00000095637","SORBS1","GO:0001725(stress fiber);GO:0003779(actin binding);GO:0005070(SH3/SH2 adaptor activity);GO:0005158(insulin receptor binding);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005813(centrosome);GO:0005829(cytosol);GO:0005856(cytoskeleton);GO:0005886(plasma membrane);GO:0005899(insulin receptor complex);GO:0005912(adherens junction);GO:0005913(cell-cell adherens junction);GO:0005915(zonula adherens);GO:0005924(cell-substrate adherens junction);GO:0005925(focal adhesion);GO:0006936(muscle contraction);GO:0007015(actin filament organization);GO:0007155(cell adhesion);GO:0007160(cell-matrix adhesion);GO:0008092(cytoskeletal protein binding);GO:0008286(insulin receptor signaling pathway);GO:0016020(membrane);GO:0016363(nuclear matrix);GO:0030054(cell junction);GO:0032869(cellular response to insulin stimulus);GO:0043149(stress fiber assembly);GO:0045121(membrane raft);GO:0045725(positive regulation of glycogen biosynthetic process);GO:0046326(positive regulation of glucose import);GO:0046628(positive regulation of insulin receptor signaling pathway);GO:0046889(positive regulation of lipid biosynthetic process);GO:0048041(focal adhesion assembly);GO:1903078(positive regulation of protein localization to plasma membrane)","03320(PPAR signaling pathway);04520(Adherens junction);04910(Insulin signaling pathway)","K06086","NA","sorbin and SH3 domain containing 1 [Source:HGNC Symbol;Acc:HGNC:14565]",{"v":0.241632,"d":"0.24"},0,{"v":0.437546,"d":"0.44"},0,0,0,"inf","inf",{"v":0.00110160372445328,"d":"0.00"},{"v":0.0726338717048776,"d":"0.07"},"up","yes"]
[137300,0,"chr3","-",15560704,15601852,"ENST00000628377",16,2214,"ENSG00000131373","HACL1","GO:0000287(magnesium ion binding);GO:0001561(fatty acid alpha-oxidation);GO:0003824(catalytic activity);GO:0005102(signaling receptor binding);GO:0005515(protein binding);GO:0005777(peroxisome);GO:0005782(peroxisomal matrix);GO:0005829(cytosol);GO:0006625(protein targeting to peroxisome);GO:0006629(lipid metabolic process);GO:0006631(fatty acid metabolic process);GO:0016829(lyase activity);GO:0016830(carbon-carbon lyase activity);GO:0030976(thiamine pyrophosphate binding);GO:0042802(identical protein binding);GO:0046872(metal ion binding);GO:0048037(cofactor binding);GO:0051259(protein complex oligomerization)","04146(Peroxisome)","K12261","EC:4.1.-.-","2-hydroxyacyl-CoA lyase 1 [Source:HGNC Symbol;Acc:HGNC:17856]",{"v":0.553108,"d":"0.55"},{"v":0.591392,"d":"0.59"},0,0,0,0,"inf","inf",{"v":0.00110954154229944,"d":"0.00"},{"v":0.0730247178111209,"d":"0.07"},"up","yes"]
[71019,0,"chr16","-",4696512,4734199,"ENST00000590193",16,2291,"ENSG00000168096","ANKS3","GO:0005515(protein binding)","NA","NA","NA","ankyrin repeat and sterile alpha motif domain containing 3 [Source:HGNC Symbol;Acc:HGNC:29422]",{"v":0.381087,"d":"0.38"},{"v":0.748327,"d":"0.75"},0,0,0,0,"inf","inf",{"v":0.00112738594596047,"d":"0.00"},{"v":0.0740220706967454,"d":"0.07"},"up","yes"]
[1910,0,"chr1","+",15526813,15571731,"ENST00000616884",14,5882,"ENSG00000116138","DNAJC16","GO:0005623(cell);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0045454(cell redox homeostasis)","NA","K09536","NA","DnaJ heat shock protein family (Hsp40) member C16 [Source:HGNC Symbol;Acc:HGNC:29157]",{"v":0.217028,"d":"0.22"},0,{"v":0.207746,"d":"0.21"},0,0,0,"inf","inf",{"v":0.00113026404369127,"d":"0.00"},{"v":0.0740220706967454,"d":"0.07"},"up","yes"]
[207465,0,"chrX","-",154487311,154490629,"ENST00000651600",2,2095,"ENSG00000126903","SLC10A3","GO:0010033(response to organic substance);GO:0015293(symporter activity);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0032526(response to retinoic acid);GO:0055085(transmembrane transport)","NA","K14343","NA","solute carrier family 10 member 3 [Source:HGNC Symbol;Acc:HGNC:22979]",{"v":0.053656,"d":"0.05"},{"v":0.21566,"d":"0.22"},{"v":0.401466,"d":"0.40"},{"v":0.009269,"d":"0.01"},{"v":12.848935,"d":"12.85"},{"v":15.071431,"d":"15.07"},{"v":0.0240168552148999,"d":"0.02"},{"v":-5.37980893393903,"d":"-5.38"},{"v":0.0011308078512715,"d":"0.00"},{"v":0.0740220706967454,"d":"0.07"},"down","yes"]
[165525,0,"chr5","+",173144546,173164057,"ENST00000393770",5,721,"ENSG00000113734","BNIP1","GO:0005484(SNAP receptor activity);GO:0005515(protein binding);GO:0005635(nuclear envelope);GO:0005737(cytoplasm);GO:0005739(mitochondrion);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0006890(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum);GO:0006915(apoptotic process);GO:0007029(endoplasmic reticulum organization);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016192(vesicle-mediated transport);GO:0016320(endoplasmic reticulum membrane fusion);GO:0030176(integral component of endoplasmic reticulum membrane);GO:0031201(SNARE complex);GO:0031966(mitochondrial membrane);GO:0043066(negative regulation of apoptotic process);GO:0043231(intracellular membrane-bounded organelle);GO:0097194(execution phase of apoptosis)","04130(SNARE interactions in vesicular transport)","NA","NA","BCL2 interacting protein 1 [Source:HGNC Symbol;Acc:HGNC:1082]",0,0,0,{"v":1.762203,"d":"1.76"},0,{"v":1.410303,"d":"1.41"},"-inf","-inf",{"v":0.00113497073865917,"d":"0.00"},{"v":0.0741609477256974,"d":"0.07"},"down","yes"]
[44131,0,"chr12","+",56021048,56036904,"ENST00000551103",7,3683,"ENSG00000123411","IKZF4","GO:0000981(DNA-binding transcription factor activity, RNA polymerase II-specific);GO:0003676(nucleic acid binding);GO:0003677(DNA binding);GO:0003700(DNA-binding transcription factor activity);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0008270(zinc ion binding);GO:0016604(nuclear body);GO:0019904(protein domain specific binding);GO:0032991(protein-containing complex);GO:0043425(bHLH transcription factor binding);GO:0043565(sequence-specific DNA binding);GO:0044212(transcription regulatory region DNA binding);GO:0045892(negative regulation of transcription, DNA-templated);GO:0045944(positive regulation of transcription by RNA polymerase II);GO:0046872(metal ion binding);GO:0051260(protein homooligomerization);GO:0051291(protein heterooligomerization)","NA","K09220","NA","IKAROS family zinc finger 4 [Source:HGNC Symbol;Acc:HGNC:13179]",0,0,0,0,{"v":0.43703,"d":"0.44"},{"v":0.247956,"d":"0.25"},"-inf","-inf",{"v":0.0011437533603494,"d":"0.00"},{"v":0.0746006455682114,"d":"0.07"},"down","yes"]
[67680,0,"chr15","+",84601009,84623716,"ENST00000546148",3,3756,"ENSG00000176371","ZSCAN2","GO:0000981(DNA-binding transcription factor activity, RNA polymerase II-specific);GO:0003676(nucleic acid binding);GO:0003677(DNA binding);GO:0003700(DNA-binding transcription factor activity);GO:0005634(nucleus);GO:0006355(regulation of transcription, DNA-templated);GO:0006357(regulation of transcription by RNA polymerase II);GO:0007275(multicellular organism development);GO:0007283(spermatogenesis);GO:0030154(cell differentiation);GO:0046872(metal ion binding)","NA","K09230","NA","zinc finger and SCAN domain containing 2 [Source:HGNC Symbol;Acc:HGNC:20994]",{"v":0.770529,"d":"0.77"},{"v":0.540617,"d":"0.54"},{"v":2.74167,"d":"2.74"},{"v":0.076337,"d":"0.08"},{"v":0.041931,"d":"0.04"},{"v":0.133797,"d":"0.13"},{"v":16.0784559538214,"d":"16.08"},{"v":4.00705696317528,"d":"4.01"},{"v":0.00114627789990692,"d":"0.00"},{"v":0.0746313191821118,"d":"0.07"},"up","yes"]
[33518,0,"chr11","+",70271922,70385312,"ENST00000648755",33,6705,"ENSG00000131626","PPFIA1","GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005925(focal adhesion);GO:0007160(cell-matrix adhesion);GO:0007165(signal transduction);GO:0007269(neurotransmitter secretion);GO:0014047(glutamate secretion);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0048786(presynaptic active zone);GO:0051497(negative regulation of stress fiber assembly);GO:1903077(negative regulation of protein localization to plasma membrane)","NA","NA","NA","PTPRF interacting protein alpha 1 [Source:HGNC Symbol;Acc:HGNC:9245]",{"v":0.004863,"d":"0.00"},{"v":0.320514,"d":"0.32"},{"v":0.857472,"d":"0.86"},0,{"v":0.006461,"d":"0.01"},{"v":0.010672,"d":"0.01"},{"v":69.039222552968,"d":"69.04"},{"v":6.10934431338319,"d":"6.11"},{"v":0.00115837353525554,"d":"0.00"},{"v":0.0752825851923064,"d":"0.08"},"up","yes"]
[179148,0,"chr7","-",55681074,55689301,"ENST00000455909",4,2451,"ENSG00000176826","FKBP9P1","NA","NA","NA","NA","FKBP prolyl isomerase 9 pseudogene 1 [Source:HGNC Symbol;Acc:HGNC:23568]",0,0,0,0,{"v":0.602175,"d":"0.60"},{"v":0.412288,"d":"0.41"},"-inf","-inf",{"v":0.0011604252052764,"d":"0.00"},{"v":0.0752825851923064,"d":"0.08"},"down","yes"]
[171064,0,"chr6","-",46221468,46325672,"ENST00000405162",4,2460,"ENSG00000172348","RCAN2","GO:0003676(nucleic acid binding);GO:0005575(cellular_component);GO:0005737(cytoplasm);GO:0008597(calcium-dependent protein serine/threonine phosphatase regulator activity);GO:0019722(calcium-mediated signaling);GO:0043666(regulation of phosphoprotein phosphatase activity);GO:0070884(regulation of calcineurin-NFAT signaling cascade)","04919(Thyroid hormone signaling pathway)","K17903","NA","regulator of calcineurin 2 [Source:HGNC Symbol;Acc:HGNC:3041]",{"v":0.585096,"d":"0.59"},{"v":1.973277,"d":"1.97"},{"v":0.323556,"d":"0.32"},{"v":0.057348,"d":"0.06"},0,0,{"v":50.2533479807491,"d":"50.25"},{"v":5.65114780967294,"d":"5.65"},{"v":0.00116370963516642,"d":"0.00"},{"v":0.0753610892078361,"d":"0.08"},"up","yes"]
[136702,0,"chr3","+",9933822,9944994,"ENST00000397170",11,1728,"ENSG00000163703","CRELD1","GO:0003197(endocardial cushion development);GO:0003279(cardiac septum development);GO:0005201(extracellular matrix structural constituent);GO:0005509(calcium ion binding);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0062023(collagen-containing extracellular matrix)","NA","NA","NA","cysteine rich with EGF like domains 1 [Source:HGNC Symbol;Acc:HGNC:14630]",{"v":4.138301,"d":"4.14"},0,{"v":0.549744,"d":"0.55"},{"v":0.013945,"d":"0.01"},{"v":0.007564,"d":"0.01"},{"v":0.023197,"d":"0.02"},{"v":104.863888516083,"d":"104.86"},{"v":6.7123741391095,"d":"6.71"},{"v":0.00116954636611406,"d":"0.00"},{"v":0.075556677609611,"d":"0.08"},"up","yes"]
[73625,0,"chr16","+",30065777,30070380,"ENST00000395240",9,1447,"ENSG00000149925","ALDOA","GO:0002576(platelet degranulation);GO:0003723(RNA binding);GO:0003779(actin binding);GO:0003824(catalytic activity);GO:0004332(fructose-bisphosphate aldolase activity);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0005615(extracellular space);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0006000(fructose metabolic process);GO:0006094(gluconeogenesis);GO:0006096(glycolytic process);GO:0006754(ATP biosynthetic process);GO:0006941(striated muscle contraction);GO:0007015(actin filament organization);GO:0007339(binding of sperm to zona pellucida);GO:0008092(cytoskeletal protein binding);GO:0008360(regulation of cell shape);GO:0015629(actin cytoskeleton);GO:0015631(tubulin binding);GO:0016020(membrane);GO:0016829(lyase activity);GO:0030388(fructose 1,6-bisphosphate metabolic process);GO:0031093(platelet alpha granule lumen);GO:0031430(M band);GO:0031674(I band);GO:0034774(secretory granule lumen);GO:0042802(identical protein binding);GO:0043312(neutrophil degranulation);GO:0045296(cadherin binding);GO:0046716(muscle cell cellular homeostasis);GO:0051289(protein homotetramerization);GO:0061621(canonical glycolysis);GO:0061827(sperm head);GO:0070061(fructose binding);GO:0070062(extracellular exosome);GO:1904724(tertiary granule lumen);GO:1904813(ficolin-1-rich granule lumen)","00010(Glycolysis / Gluconeogenesis);00030(Pentose phosphate pathway);00051(Fructose and mannose metabolism);04066(HIF-1 signaling pathway)","NA","NA","aldolase, fructose-bisphosphate A [Source:HGNC Symbol;Acc:HGNC:414]",{"v":3.693714,"d":"3.69"},{"v":3.388364,"d":"3.39"},{"v":0.061624,"d":"0.06"},{"v":38.054199,"d":"38.05"},{"v":35.964001,"d":"35.96"},{"v":15.9679,"d":"15.97"},{"v":0.0793867275056925,"d":"0.08"},{"v":-3.65495836329186,"d":"-3.65"},{"v":0.0011708893337245,"d":"0.00"},{"v":0.075556677609611,"d":"0.08"},"down","yes"]
[139268,0,"chr3","+",46987990,47009704,"ENST00000651747",53,8605,"ENSG00000160796","NBEAL2","GO:0005515(protein binding);GO:0005783(endoplasmic reticulum);GO:0005886(plasma membrane);GO:0030220(platelet formation);GO:0043312(neutrophil degranulation);GO:0070821(tertiary granule membrane);GO:0101003(ficolin-1-rich granule membrane)","NA","K23286","NA","neurobeachin like 2 [Source:HGNC Symbol;Acc:HGNC:31928]",0,{"v":0.148276,"d":"0.15"},{"v":0.13788,"d":"0.14"},0,0,0,"inf","inf",{"v":0.00117372153018067,"d":"0.00"},{"v":0.0756051475025953,"d":"0.08"},"up","yes"]
[47415,0,"chr12","-",105174208,105236083,"ENST00000551662",21,2190,"ENSG00000136044","APPL2","GO:0001726(ruffle);GO:0001786(phosphatidylserine binding);GO:0002024(diet induced thermogenesis);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005768(endosome);GO:0005886(plasma membrane);GO:0006606(protein import into nucleus);GO:0007049(cell cycle);GO:0007165(signal transduction);GO:0007179(transforming growth factor beta receptor signaling pathway);GO:0008283(cell population proliferation);GO:0009631(cold acclimation);GO:0010008(endosome membrane);GO:0010762(regulation of fibroblast migration);GO:0016020(membrane);GO:0023052(signaling);GO:0030670(phagocytic vesicle membrane);GO:0031410(cytoplasmic vesicle);GO:0031901(early endosome membrane);GO:0031982(vesicle);GO:0032009(early phagosome);GO:0032587(ruffle membrane);GO:0033211(adiponectin-activated signaling pathway);GO:0034143(regulation of toll-like receptor 4 signaling pathway);GO:0035091(phosphatidylinositol binding);GO:0035729(cellular response to hepatocyte growth factor stimulus);GO:0036186(early phagosome membrane);GO:0042593(glucose homeostasis);GO:0042803(protein homodimerization activity);GO:0042995(cell projection);GO:0044354(macropinosome);GO:0044877(protein-containing complex binding);GO:0045088(regulation of innate immune response);GO:0045335(phagocytic vesicle);GO:0046322(negative regulation of fatty acid oxidation);GO:0046325(negative regulation of glucose import);GO:0050768(negative regulation of neurogenesis);GO:0051289(protein homotetramerization);GO:0060100(positive regulation of phagocytosis, engulfment);GO:0070062(extracellular exosome);GO:0120162(positive regulation of cold-induced thermogenesis);GO:1900016(negative regulation of cytokine production involved in inflammatory response);GO:1900077(negative regulation of cellular response to insulin stimulus);GO:1905303(positive regulation of macropinocytosis);GO:1905451(positive regulation of Fc-gamma receptor signaling pathway involved in phagocytosis);GO:2000178(negative regulation of neural precursor cell proliferation)","NA","K20132","NA","adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2 [Source:HGNC Symbol;Acc:HGNC:18242]",{"v":2.019556,"d":"2.02"},{"v":8.703931,"d":"8.70"},{"v":4.775659,"d":"4.78"},0,{"v":0.249399,"d":"0.25"},0,{"v":62.145982942995,"d":"62.15"},{"v":5.95758923474887,"d":"5.96"},{"v":0.00119125671496734,"d":"0.00"},{"v":0.0765988609818819,"d":"0.08"},"up","yes"]
[7911,0,"chr1","+",85062386,85133027,"ENST00000464801",23,3477,"ENSG00000162643","WDR63","GO:0005515(protein binding);GO:0007018(microtubule-based movement);GO:0008574(ATP-dependent microtubule motor activity, plus-end-directed);GO:0030286(dynein complex);GO:0045503(dynein light chain binding);GO:0045504(dynein heavy chain binding)","NA","NA","NA","WD repeat domain 63 [Source:HGNC Symbol;Acc:HGNC:30711]",0,0,0,{"v":0.293623,"d":"0.29"},{"v":0.390419,"d":"0.39"},0,"-inf","-inf",{"v":0.00120082700291693,"d":"0.00"},{"v":0.0769280782114485,"d":"0.08"},"down","yes"]
[3518,0,"chr1","-",28613247,28643085,"ENST00000495422",5,624,"ENSG00000120656","TAF12","GO:0000124(SAGA complex);GO:0003677(DNA binding);GO:0003700(DNA-binding transcription factor activity);GO:0003713(transcription coactivator activity);GO:0004402(histone acetyltransferase activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005669(transcription factor TFIID complex);GO:0006352(DNA-templated transcription, initiation);GO:0006366(transcription by RNA polymerase II);GO:0006367(transcription initiation from RNA polymerase II promoter);GO:0008134(transcription factor binding);GO:0017025(TBP-class protein binding);GO:0030914(STAGA complex);GO:0033276(transcription factor TFTC complex);GO:0043966(histone H3 acetylation);GO:0046695(SLIK (SAGA-like) complex);GO:0046982(protein heterodimerization activity);GO:0051091(positive regulation of DNA-binding transcription factor activity);GO:0051123(RNA polymerase II preinitiation complex assembly);GO:1901796(regulation of signal transduction by p53 class mediator);GO:1903508(positive regulation of nucleic acid-templated transcription)","03022(Basal transcription factors)","K03126","NA","TATA-box binding protein associated factor 12 [Source:HGNC Symbol;Acc:HGNC:11545]",{"v":0.168857,"d":"0.17"},{"v":0.215183,"d":"0.22"},{"v":0.364939,"d":"0.36"},{"v":5.461395,"d":"5.46"},{"v":2.511735,"d":"2.51"},{"v":1.96668,"d":"1.97"},{"v":0.0753514403192818,"d":"0.08"},{"v":-3.73022110102229,"d":"-3.73"},{"v":0.00120091050010122,"d":"0.00"},{"v":0.0769280782114485,"d":"0.08"},"down","yes"]
[112605,0,"chr2","-",55866612,55923776,"ENST00000635671",9,1809,"ENSG00000115380","EFEMP1","GO:0005006(epidermal growth factor-activated receptor activity);GO:0005154(epidermal growth factor receptor binding);GO:0005201(extracellular matrix structural constituent);GO:0005509(calcium ion binding);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0005615(extracellular space);GO:0006355(regulation of transcription, DNA-templated);GO:0007173(epidermal growth factor receptor signaling pathway);GO:0007601(visual perception);GO:0008083(growth factor activity);GO:0010469(regulation of signaling receptor activity);GO:0018108(peptidyl-tyrosine phosphorylation);GO:0031012(extracellular matrix);GO:0032331(negative regulation of chondrocyte differentiation);GO:0043010(camera-type eye development);GO:0048048(embryonic eye morphogenesis);GO:0048050(post-embryonic eye morphogenesis);GO:0062023(collagen-containing extracellular matrix);GO:0070062(extracellular exosome)","NA","NA","NA","EGF containing fibulin extracellular matrix protein 1 [Source:HGNC Symbol;Acc:HGNC:3218]",{"v":1.711036,"d":"1.71"},{"v":28.687485,"d":"28.69"},{"v":1.291263,"d":"1.29"},{"v":0.310802,"d":"0.31"},{"v":0.006874,"d":"0.01"},{"v":0.60067,"d":"0.60"},{"v":34.507455795528,"d":"34.51"},{"v":5.10883620394091,"d":"5.11"},{"v":0.00120272910608595,"d":"0.00"},{"v":0.0769280782114485,"d":"0.08"},"up","yes"]
[151177,0,"chr4","-",48497363,48780299,"ENST00000358350",64,11706,"ENSG00000075539","FRYL","GO:0000902(cell morphogenesis);GO:0005938(cell cortex);GO:0031175(neuron projection development)","NA","NA","NA","FRY like transcription coactivator [Source:HGNC Symbol;Acc:HGNC:29127]",{"v":0.054427,"d":"0.05"},{"v":0.827276,"d":"0.83"},{"v":0.673638,"d":"0.67"},{"v":0.033899,"d":"0.03"},{"v":0.028871,"d":"0.03"},{"v":0.024659,"d":"0.02"},{"v":17.7897608345057,"d":"17.79"},{"v":4.15297521003477,"d":"4.15"},{"v":0.00122436472511085,"d":"0.00"},{"v":0.0781742890391515,"d":"0.08"},"up","yes"]
[9116,0,"chr1","+",109494115,109500440,"ENST00000430195",4,5077,"ENSG00000174151","CYB561D1","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0046872(metal ion binding);GO:0055114(oxidation-reduction process)","NA","NA","NA","cytochrome b561 family member D1 [Source:HGNC Symbol;Acc:HGNC:26804]",{"v":0.583446,"d":"0.58"},{"v":0.299408,"d":"0.30"},0,{"v":0.000274,"d":"0.00"},{"v":0.000205,"d":"0.00"},{"v":0.000388,"d":"0.00"},{"v":1018.2860438293,"d":"1018.29"},{"v":9.99192716635766,"d":"9.99"},{"v":0.00123570358147711,"d":"0.00"},{"v":0.0787598440615145,"d":"0.08"},"up","yes"]
[127096,0,"chr20","+",44475888,44494603,"ENST00000372904",6,6234,"ENSG00000124120","TTPAL","GO:0016020(membrane)","NA","NA","NA","alpha tocopherol transfer protein like [Source:HGNC Symbol;Acc:HGNC:16114]",{"v":0.028349,"d":"0.03"},0,{"v":0.009431,"d":"0.01"},{"v":2.947033,"d":"2.95"},{"v":0.731894,"d":"0.73"},{"v":0.000657,"d":"0.00"},{"v":0.0102674650177846,"d":"0.01"},{"v":-6.60577615784657,"d":"-6.61"},{"v":0.00124210398555156,"d":"0.00"},{"v":0.0790291379949007,"d":"0.08"},"down","yes"]
[47534,0,"chr12","+",107685808,107693075,"ENST00000547995",5,569,"ENSG00000136045","PWP1","GO:0005515(protein binding);GO:0005634(nucleus);GO:0005694(chromosome);GO:0005730(nucleolus);GO:0005794(Golgi apparatus);GO:0006351(transcription, DNA-templated);GO:0033140(negative regulation of peptidyl-serine phosphorylation of STAT protein);GO:0034773(histone H4-K20 trimethylation);GO:0042254(ribosome biogenesis);GO:1901838(positive regulation of transcription of nucleolar large rRNA by RNA polymerase I);GO:1990889(H4K20me3 modified histone binding);GO:2000738(positive regulation of stem cell differentiation)","NA","K14791","NA","PWP1 homolog, endonuclein [Source:HGNC Symbol;Acc:HGNC:17015]",0,0,0,{"v":2.243378,"d":"2.24"},{"v":1.781601,"d":"1.78"},0,"-inf","-inf",{"v":0.00125198163039024,"d":"0.00"},{"v":0.0793909175307911,"d":"0.08"},"down","yes"]
[160581,0,"chr5","+",82382945,82386516,"ENST00000502523",2,2511,"ENSG00000205464","ATP6AP1L","GO:0015991(ATP hydrolysis coupled proton transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0030641(regulation of cellular pH);GO:0033180(proton-transporting V-type ATPase, V1 domain);GO:0033181(plasma membrane proton-transporting V-type ATPase complex);GO:0046933(proton-transporting ATP synthase activity, rotational mechanism);GO:0046961(proton-transporting ATPase activity, rotational mechanism)","NA","NA","NA","ATPase H+ transporting accessory protein 1 like [Source:HGNC Symbol;Acc:HGNC:28091]",{"v":0.470699,"d":"0.47"},{"v":0.452829,"d":"0.45"},0,0,0,0,"inf","inf",{"v":0.00125216063157565,"d":"0.00"},{"v":0.0793909175307911,"d":"0.08"},"up","yes"]
[45196,0,"chr12","+",64452131,64501741,"ENST00000650762",20,2459,"ENSG00000183735","TBK1","GO:0000166(nucleotide binding);GO:0002218(activation of innate immune response);GO:0002376(immune system process);GO:0003676(nucleic acid binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005515(protein binding);GO:0005524(ATP binding);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0006468(protein phosphorylation);GO:0006954(inflammatory response);GO:0007249(I-kappaB kinase/NF-kappaB signaling);GO:0009615(response to virus);GO:0010008(endosome membrane);GO:0010468(regulation of gene expression);GO:0010629(negative regulation of gene expression);GO:0016032(viral process);GO:0016235(aggresome);GO:0016239(positive regulation of macroautophagy);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0016740(transferase activity);GO:0018105(peptidyl-serine phosphorylation);GO:0018107(peptidyl-threonine phosphorylation);GO:0019903(protein phosphatase binding);GO:0031323(regulation of cellular metabolic process);GO:0032479(regulation of type I interferon production);GO:0032480(negative regulation of type I interferon production);GO:0032481(positive regulation of type I interferon production);GO:0032606(type I interferon production);GO:0032727(positive regulation of interferon-alpha production);GO:0032728(positive regulation of interferon-beta production);GO:0033138(positive regulation of peptidyl-serine phosphorylation);GO:0035666(TRIF-dependent toll-like receptor signaling pathway);GO:0042802(identical protein binding);GO:0043123(positive regulation of I-kappaB kinase/NF-kappaB signaling);GO:0044565(dendritic cell proliferation);GO:0045087(innate immune response);GO:0045359(positive regulation of interferon-beta biosynthetic process);GO:0045944(positive regulation of transcription by RNA polymerase II);GO:0050830(defense response to Gram-positive bacterium);GO:0051219(phosphoprotein binding);GO:0051607(defense response to virus);GO:0060340(positive regulation of type I interferon-mediated signaling pathway);GO:0071345(cellular response to cytokine stimulus);GO:1901214(regulation of neuron death);GO:1904417(positive regulation of xenophagy)","04014(Ras signaling pathway);04137(Mitophagy - animal);04620(Toll-like receptor signaling pathway);04621(NOD-like receptor signaling pathway);04622(RIG-I-like receptor signaling pathway);04623(Cytosolic DNA-sensing pathway);04657(IL-17 signaling pathway);05160(Hepatitis C);05161(Hepatitis B);05162(Measles);05163(Human cytomegalovirus infection);05164(Influenza A);05165(Human papillomavirus infection);05167(Kaposi sarcoma-associated herpesvirus infection);05168(Herpes simplex virus 1 infection);05169(Epstein-Barr virus infection);05170(Human immunodeficiency virus 1 infection)","K05410","EC:2.7.11.10","TANK binding kinase 1 [Source:HGNC Symbol;Acc:HGNC:11584]",{"v":0.440547,"d":"0.44"},0,{"v":0.498814,"d":"0.50"},0,0,0,"inf","inf",{"v":0.00126222438367082,"d":"0.00"},{"v":0.0798895676981894,"d":"0.08"},"up","yes"]
[153158,0,"chr4","+",87975650,87983410,"ENST00000614857",8,1558,"ENSG00000118785","SPP1","GO:0001503(ossification);GO:0001649(osteoblast differentiation);GO:0005125(cytokine activity);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0005615(extracellular space);GO:0005788(endoplasmic reticulum lumen);GO:0005794(Golgi apparatus);GO:0006710(androgen catabolic process);GO:0006954(inflammatory response);GO:0007155(cell adhesion);GO:0007566(embryo implantation);GO:0010033(response to organic substance);GO:0010469(regulation of signaling receptor activity);GO:0030154(cell differentiation);GO:0030198(extracellular matrix organization);GO:0031214(biomineral tissue development);GO:0031982(vesicle);GO:0033280(response to vitamin D);GO:0042995(cell projection);GO:0043687(post-translational protein modification);GO:0044267(cellular protein metabolic process);GO:0045780(positive regulation of bone resorption);GO:0045893(positive regulation of transcription, DNA-templated);GO:0046697(decidualization);GO:0048471(perinuclear region of cytoplasm);GO:0048545(response to steroid hormone);GO:0048685(negative regulation of collateral sprouting of intact axon in response to injury);GO:0050840(extracellular matrix binding);GO:0070062(extracellular exosome);GO:0071394(cellular response to testosterone stimulus);GO:2000866(positive regulation of estradiol secretion)","04151(PI3K-Akt signaling pathway);04371(Apelin signaling pathway);04510(Focal adhesion);04512(ECM-receptor interaction);04620(Toll-like receptor signaling pathway);05165(Human papillomavirus infection)","K06250","NA","secreted phosphoprotein 1 [Source:HGNC Symbol;Acc:HGNC:11255]",0,0,0,{"v":0.563505,"d":"0.56"},0,{"v":0.790287,"d":"0.79"},"-inf","-inf",{"v":0.00127061638044721,"d":"0.00"},{"v":0.0802808575680821,"d":"0.08"},"down","yes"]
[27969,0,"chr11","+",17295322,17331523,"ENST00000622082",12,1369,"ENSG00000070081","NUCB2","GO:0003677(DNA binding);GO:0005509(calcium ion binding);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0005615(extracellular space);GO:0005634(nucleus);GO:0005635(nuclear envelope);GO:0005640(nuclear outer membrane);GO:0005737(cytoplasm);GO:0005783(endoplasmic reticulum);GO:0005793(endoplasmic reticulum-Golgi intermediate compartment);GO:0005794(Golgi apparatus);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0016020(membrane);GO:0032099(negative regulation of appetite);GO:0046872(metal ion binding);GO:0070062(extracellular exosome)","NA","K20371","NA","nucleobindin 2 [Source:HGNC Symbol;Acc:HGNC:8044]",0,0,{"v":0.012499,"d":"0.01"},{"v":1.032301,"d":"1.03"},{"v":0.01841,"d":"0.02"},{"v":1.269188,"d":"1.27"},{"v":0.00538773455223697,"d":"0.01"},{"v":-7.53610551211079,"d":"-7.54"},{"v":0.00127356240191654,"d":"0.00"},{"v":0.0803272952458819,"d":"0.08"},"down","yes"]
[199918,0,"chr9","+",130444988,130501255,"ENST00000372393",16,1548,"ENSG00000130707","ASS1","GO:0000050(urea cycle);GO:0000052(citrulline metabolic process);GO:0000053(argininosuccinate metabolic process);GO:0000166(nucleotide binding);GO:0001822(kidney development);GO:0001889(liver development);GO:0003723(RNA binding);GO:0004055(argininosuccinate synthase activity);GO:0005515(protein binding);GO:0005524(ATP binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005739(mitochondrion);GO:0005741(mitochondrial outer membrane);GO:0005764(lysosome);GO:0005783(endoplasmic reticulum);GO:0005829(cytosol);GO:0006526(arginine biosynthetic process);GO:0006531(aspartate metabolic process);GO:0006953(acute-phase response);GO:0007494(midgut development);GO:0007568(aging);GO:0007584(response to nutrient);GO:0007623(circadian rhythm);GO:0008652(cellular amino acid biosynthetic process);GO:0009636(response to toxic substance);GO:0010043(response to zinc ion);GO:0010046(response to mycotoxin);GO:0014075(response to amine);GO:0015643(toxic substance binding);GO:0016597(amino acid binding);GO:0016874(ligase activity);GO:0032355(response to estradiol);GO:0032496(response to lipopolysaccharide);GO:0042493(response to drug);GO:0042802(identical protein binding);GO:0043005(neuron projection);GO:0043025(neuronal cell body);GO:0043200(response to amino acid);GO:0043204(perikaryon);GO:0043434(response to peptide hormone);GO:0045429(positive regulation of nitric oxide biosynthetic process);GO:0048545(response to steroid hormone);GO:0051384(response to glucocorticoid);GO:0060416(response to growth hormone);GO:0060539(diaphragm development);GO:0070062(extracellular exosome);GO:0070542(response to fatty acid);GO:0070852(cell body fiber);GO:0071222(cellular response to lipopolysaccharide);GO:0071230(cellular response to amino acid stimulus);GO:0071242(cellular response to ammonium ion);GO:0071320(cellular response to cAMP);GO:0071346(cellular response to interferon-gamma);GO:0071356(cellular response to tumor necrosis factor);GO:0071377(cellular response to glucagon stimulus);GO:0071400(cellular response to oleic acid);GO:0071418(cellular response to amine stimulus);GO:0071499(cellular response to laminar fluid shear stress);GO:0071549(cellular response to dexamethasone stimulus);GO:1903038(negative regulation of leukocyte cell-cell adhesion)","00220(Arginine biosynthesis);00250(Alanine, aspartate and glutamate metabolism);05418(Fluid shear stress and atherosclerosis)","NA","NA","argininosuccinate synthase 1 [Source:HGNC Symbol;Acc:HGNC:758]",0,0,0,0,{"v":0.900933,"d":"0.90"},{"v":0.588,"d":"0.59"},"-inf","-inf",{"v":0.00128156689706393,"d":"0.00"},{"v":0.0806920716990166,"d":"0.08"},"down","yes"]
[189070,0,"chr8","+",48049580,48061315,"ENST00000521628",2,1033,"ENSG00000169139","UBE2V2","GO:0000209(protein polyubiquitination);GO:0000729(DNA double-strand break processing);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0006282(regulation of DNA repair);GO:0006301(postreplication repair);GO:0006303(double-strand break repair via nonhomologous end joining);GO:0008283(cell population proliferation);GO:0010976(positive regulation of neuron projection development);GO:0016567(protein ubiquitination);GO:0031372(UBC13-MMS2 complex);GO:0032436(positive regulation of proteasomal ubiquitin-dependent protein catabolic process);GO:0042275(error-free postreplication DNA repair);GO:0043524(negative regulation of neuron apoptotic process);GO:0045739(positive regulation of DNA repair);GO:0051965(positive regulation of synapse assembly);GO:0061631(ubiquitin conjugating enzyme activity);GO:0070062(extracellular exosome);GO:0070534(protein K63-linked ubiquitination)","NA","K10704","NA","ubiquitin conjugating enzyme E2 V2 [Source:HGNC Symbol;Acc:HGNC:12495]",{"v":0.383276,"d":"0.38"},{"v":0.41015,"d":"0.41"},{"v":0.476216,"d":"0.48"},{"v":10.406301,"d":"10.41"},{"v":0.326824,"d":"0.33"},{"v":13.91411,"d":"13.91"},{"v":0.0515125530307964,"d":"0.05"},{"v":-4.27893214605221,"d":"-4.28"},{"v":0.00128387948409314,"d":"0.00"},{"v":0.0806978229361657,"d":"0.08"},"down","yes"]
[115261,0,"chr2","-",96595512,96638320,"ENST00000597150",21,2811,"ENSG00000114982","KANSL3","GO:0000123(histone acetyltransferase complex);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005730(nucleolus);GO:0006325(chromatin organization);GO:0043231(intracellular membrane-bounded organelle);GO:0043981(histone H4-K5 acetylation);GO:0043982(histone H4-K8 acetylation);GO:0043984(histone H4-K16 acetylation);GO:0043995(histone acetyltransferase activity (H4-K5 specific));GO:0043996(histone acetyltransferase activity (H4-K8 specific));GO:0044545(NSL complex);GO:0046972(histone acetyltransferase activity (H4-K16 specific))","NA","K16719","NA","KAT8 regulatory NSL complex subunit 3 [Source:HGNC Symbol;Acc:HGNC:25473]",{"v":0.509186,"d":"0.51"},{"v":0.313621,"d":"0.31"},0,0,0,0,"inf","inf",{"v":0.00128830434652199,"d":"0.00"},{"v":0.080836091380214,"d":"0.08"},"up","yes"]
[206817,0,"chrX","-",150766339,150898816,"ENST00000613030",12,3742,"ENSG00000102181","CD99L2","GO:0005515(protein binding);GO:0005886(plasma membrane);GO:0005913(cell-cell adherens junction);GO:0005925(focal adhesion);GO:0007155(cell adhesion);GO:0009986(cell surface);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0030054(cell junction);GO:0050904(diapedesis);GO:2000391(positive regulation of neutrophil extravasation);GO:2000409(positive regulation of T cell extravasation)","NA","NA","NA","CD99 molecule like 2 [Source:HGNC Symbol;Acc:HGNC:18237]",{"v":0.55485,"d":"0.55"},{"v":1.54743,"d":"1.55"},{"v":3.458905,"d":"3.46"},0,{"v":0.091519,"d":"0.09"},{"v":0.100623,"d":"0.10"},{"v":28.943099374421,"d":"28.94"},{"v":4.85514751615871,"d":"4.86"},{"v":0.00130643239181042,"d":"0.00"},{"v":0.0818322220594354,"d":"0.08"},"up","yes"]
[112829,0,"chr2","-",61477935,61494743,"ENST00000481073",14,3706,"ENSG00000082898","XPO1","GO:0000054(ribosomal subunit export from nucleus);GO:0000055(ribosomal large subunit export from nucleus);GO:0000056(ribosomal small subunit export from nucleus);GO:0000122(negative regulation of transcription by RNA polymerase II);GO:0000776(kinetochore);GO:0003723(RNA binding);GO:0005049(nuclear export signal receptor activity);GO:0005215(transporter activity);GO:0005515(protein binding);GO:0005623(cell);GO:0005634(nucleus);GO:0005635(nuclear envelope);GO:0005642(annulate lamellae);GO:0005654(nucleoplasm);GO:0005730(nucleolus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0006611(protein export from nucleus);GO:0006886(intracellular protein transport);GO:0006913(nucleocytoplasmic transport);GO:0008536(Ran GTPase binding);GO:0008565(protein transporter activity);GO:0010824(regulation of centrosome duplication);GO:0015030(Cajal body);GO:0015031(protein transport);GO:0016020(membrane);GO:0016032(viral process);GO:0019904(protein domain specific binding);GO:0031965(nuclear membrane);GO:0032991(protein-containing complex);GO:0034504(protein localization to nucleus);GO:0042176(regulation of protein catabolic process);GO:0042254(ribosome biogenesis);GO:0042493(response to drug);GO:0043231(intracellular membrane-bounded organelle);GO:0043488(regulation of mRNA stability);GO:0043657(host cell);GO:0046825(regulation of protein export from nucleus);GO:0051028(mRNA transport);GO:0075733(intracellular transport of virus);GO:1990904(ribonucleoprotein complex)","03008(Ribosome biogenesis in eukaryotes);03013(RNA transport);05164(Influenza A);05166(Human T-cell leukemia virus 1 infection)","K14290","NA","exportin 1 [Source:HGNC Symbol;Acc:HGNC:12825]",{"v":7.987457,"d":"7.99"},{"v":41.107315,"d":"41.11"},{"v":34.25312,"d":"34.25"},{"v":6.140036,"d":"6.14"},{"v":3.441014,"d":"3.44"},{"v":4.574226,"d":"4.57"},{"v":5.88811493325881,"d":"5.89"},{"v":2.55780583240447,"d":"2.56"},{"v":0.00131212936324277,"d":"0.00"},{"v":0.0820476071714453,"d":"0.08"},"up","yes"]
[204898,0,"chrX","+",101101048,101162987,"ENST00000423383",20,2314,"ENSG00000102384","CENPI","GO:0000775(chromosome, centromeric region);GO:0000776(kinetochore);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005694(chromosome);GO:0005829(cytosol);GO:0007548(sex differentiation);GO:0016604(nuclear body);GO:0034080(CENP-A containing nucleosome assembly);GO:0034508(centromere complex assembly)","NA","K11501","NA","centromere protein I [Source:HGNC Symbol;Acc:HGNC:3968]",0,0,0,{"v":0.492109,"d":"0.49"},{"v":0.463397,"d":"0.46"},0,"-inf","-inf",{"v":0.00132064473261809,"d":"0.00"},{"v":0.0823014366116581,"d":"0.08"},"down","yes"]
[17143,0,"chr1","-",227731193,227735411,"ENST00000615711",6,2591,"ENSG00000081692","JMJD4","GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0016491(oxidoreductase activity);GO:0016706(2-oxoglutarate-dependent dioxygenase activity);GO:0018126(protein hydroxylation);GO:0045905(positive regulation of translational termination);GO:0046872(metal ion binding);GO:0051213(dioxygenase activity);GO:0055114(oxidation-reduction process)","NA","NA","NA","jumonji domain containing 4 [Source:HGNC Symbol;Acc:HGNC:25724]",{"v":1.312254,"d":"1.31"},{"v":0.762718,"d":"0.76"},{"v":0.7782,"d":"0.78"},{"v":0.089166,"d":"0.09"},{"v":0.098439,"d":"0.10"},{"v":0.050586,"d":"0.05"},{"v":11.9785046454316,"d":"11.98"},{"v":3.58237591325847,"d":"3.58"},{"v":0.00132071944796578,"d":"0.00"},{"v":0.0823014366116581,"d":"0.08"},"up","yes"]
[114074,0,"chr2","-",74474102,74482996,"ENST00000290418",9,2835,"ENSG00000135637","CCDC142","NA","NA","NA","NA","coiled-coil domain containing 142 [Source:HGNC Symbol;Acc:HGNC:25889]",0,0,0,0,{"v":0.367072,"d":"0.37"},{"v":0.412344,"d":"0.41"},"-inf","-inf",{"v":0.0013312965447526,"d":"0.00"},{"v":0.0828184990939415,"d":"0.08"},"down","yes"]
[14674,0,"chr1","+",184051718,184071220,"ENST00000367518",4,996,"ENSG00000198860","TSEN15","GO:0000213(tRNA-intron endonuclease activity);GO:0003676(nucleic acid binding);GO:0004518(nuclease activity);GO:0004519(endonuclease activity);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005730(nucleolus);GO:0006388(tRNA splicing, via endonucleolytic cleavage and ligation);GO:0006397(mRNA processing);GO:0008033(tRNA processing);GO:0090305(nucleic acid phosphodiester bond hydrolysis);GO:0090501(RNA phosphodiester bond hydrolysis);GO:0090502(RNA phosphodiester bond hydrolysis, endonucleolytic)","NA","K15324","NA","tRNA splicing endonuclease subunit 15 [Source:HGNC Symbol;Acc:HGNC:16791]",{"v":0.12504,"d":"0.13"},{"v":0.189343,"d":"0.19"},{"v":0.194015,"d":"0.19"},{"v":2.545255,"d":"2.55"},{"v":1.918891,"d":"1.92"},{"v":1.603928,"d":"1.60"},{"v":0.0837824324489121,"d":"0.08"},{"v":-3.57720841930817,"d":"-3.58"},{"v":0.00134086052433064,"d":"0.00"},{"v":0.0832708766648415,"d":"0.08"},"down","yes"]
[178825,0,"chr7","-",45912245,45921272,"ENST00000381083",5,2631,"ENSG00000146674","IGFBP3","GO:0001558(regulation of cell growth);GO:0001649(osteoblast differentiation);GO:0001933(negative regulation of protein phosphorylation);GO:0001968(fibronectin binding);GO:0005515(protein binding);GO:0005520(insulin-like growth factor binding);GO:0005576(extracellular region);GO:0005615(extracellular space);GO:0005634(nucleus);GO:0005788(endoplasmic reticulum lumen);GO:0006468(protein phosphorylation);GO:0006915(apoptotic process);GO:0008160(protein tyrosine phosphatase activator activity);GO:0008285(negative regulation of cell population proliferation);GO:0009968(negative regulation of signal transduction);GO:0010906(regulation of glucose metabolic process);GO:0014912(negative regulation of smooth muscle cell migration);GO:0016942(insulin-like growth factor binding protein complex);GO:0019838(growth factor binding);GO:0031994(insulin-like growth factor I binding);GO:0031995(insulin-like growth factor II binding);GO:0040008(regulation of growth);GO:0042567(insulin-like growth factor ternary complex);GO:0042981(regulation of apoptotic process);GO:0043065(positive regulation of apoptotic process);GO:0043410(positive regulation of MAPK cascade);GO:0043567(regulation of insulin-like growth factor receptor signaling pathway);GO:0043568(positive regulation of insulin-like growth factor receptor signaling pathway);GO:0043666(regulation of phosphoprotein phosphatase activity);GO:0043687(post-translational protein modification);GO:0044267(cellular protein metabolic process);GO:0044342(type B pancreatic cell proliferation);GO:0045663(positive regulation of myoblast differentiation);GO:0046872(metal ion binding);GO:0048662(negative regulation of smooth muscle cell proliferation)","04115(p53 signaling pathway);04218(Cellular senescence);05202(Transcriptional misregulation in cancer)","NA","NA","insulin like growth factor binding protein 3 [Source:HGNC Symbol;Acc:HGNC:5472]",{"v":29.358124,"d":"29.36"},{"v":21.396317,"d":"21.40"},{"v":20.920488,"d":"20.92"},{"v":2.75819,"d":"2.76"},{"v":4.385635,"d":"4.39"},{"v":6.632997,"d":"6.63"},{"v":5.20257349626786,"d":"5.20"},{"v":2.37922544092211,"d":"2.38"},{"v":0.00135547778248722,"d":"0.00"},{"v":0.0838937211641166,"d":"0.08"},"up","yes"]
[165796,0,"chr5","+",176647505,176656956,"ENST00000504168",8,884,"ENSG00000048140","TSPAN17","GO:0000151(ubiquitin ligase complex);GO:0004842(ubiquitin-protein transferase activity);GO:0005887(integral component of plasma membrane);GO:0007166(cell surface receptor signaling pathway);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016567(protein ubiquitination);GO:0019899(enzyme binding);GO:0072594(establishment of protein localization to organelle)","NA","K10303","NA","tetraspanin 17 [Source:HGNC Symbol;Acc:HGNC:13594]",0,{"v":1.612411,"d":"1.61"},{"v":0.95959,"d":"0.96"},0,0,0,"inf","inf",{"v":0.00135550823901284,"d":"0.00"},{"v":0.0838937211641166,"d":"0.08"},"up","yes"]
[127588,0,"chr20","+",47501887,47656872,"ENST00000371998",23,7961,"ENSG00000124151","NCOA3","GO:0000790(nuclear chromatin);GO:0000981(DNA-binding transcription factor activity, RNA polymerase II-specific);GO:0000993(RNA polymerase II complex binding);GO:0003713(transcription coactivator activity);GO:0004402(histone acetyltransferase activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0006355(regulation of transcription, DNA-templated);GO:0010628(positive regulation of gene expression);GO:0016573(histone acetylation);GO:0016740(transferase activity);GO:0016746(transferase activity, transferring acyl groups);GO:0016922(nuclear receptor binding);GO:0030374(nuclear receptor transcription coactivator activity);GO:0030521(androgen receptor signaling pathway);GO:0032870(cellular response to hormone stimulus);GO:0032991(protein-containing complex);GO:0035257(nuclear hormone receptor binding);GO:0035624(receptor transactivation);GO:0043697(cell dedifferentiation);GO:0045618(positive regulation of keratinocyte differentiation);GO:0045893(positive regulation of transcription, DNA-templated);GO:0045944(positive regulation of transcription by RNA polymerase II);GO:0046966(thyroid hormone receptor binding);GO:0046982(protein heterodimerization activity);GO:0046983(protein dimerization activity);GO:0047485(protein N-terminus binding);GO:0050681(androgen receptor binding);GO:0070062(extracellular exosome);GO:0071392(cellular response to estradiol stimulus);GO:0097718(disordered domain specific binding);GO:1902459(positive regulation of stem cell population maintenance);GO:2000035(regulation of stem cell division);GO:2001141(regulation of RNA biosynthetic process)","01522(Endocrine resistance);04915(Estrogen signaling pathway);04919(Thyroid hormone signaling pathway);05200(Pathways in cancer);05224(Breast cancer)","K11256","EC:2.3.1.48","nuclear receptor coactivator 3 [Source:HGNC Symbol;Acc:HGNC:7670]",{"v":0.13098,"d":"0.13"},{"v":0.096218,"d":"0.10"},{"v":0.13652,"d":"0.14"},{"v":0.162724,"d":"0.16"},{"v":2.195093,"d":"2.20"},{"v":2.552592,"d":"2.55"},{"v":0.074070815689691,"d":"0.07"},{"v":-3.75495096510166,"d":"-3.75"},{"v":0.00135861076700853,"d":"0.00"},{"v":0.0839067447054355,"d":"0.08"},"down","yes"]
[69926,0,"chr16","-",1997655,2009821,"ENST00000563630",12,3368,"ENSG00000167962","ZNF598","GO:0003676(nucleic acid binding)","NA","K22381","EC:2.3.2.27","zinc finger protein 598 [Source:HGNC Symbol;Acc:HGNC:28079]",{"v":0.058957,"d":"0.06"},{"v":0.160861,"d":"0.16"},{"v":0.041879,"d":"0.04"},{"v":5.050348,"d":"5.05"},{"v":2.05901,"d":"2.06"},{"v":0.044354,"d":"0.04"},{"v":0.0365819870858654,"d":"0.04"},{"v":-4.77272274724515,"d":"-4.77"},{"v":0.00136033780984039,"d":"0.00"},{"v":0.0839067447054355,"d":"0.08"},"down","yes"]
[143937,0,"chr3","-",127689066,127823185,"ENST00000434178",8,4941,"ENSG00000074416","MGLL","GO:0004622(lysophospholipase activity);GO:0005515(protein binding);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0005789(endoplasmic reticulum membrane);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0006629(lipid metabolic process);GO:0006631(fatty acid metabolic process);GO:0006633(fatty acid biosynthetic process);GO:0006954(inflammatory response);GO:0009966(regulation of signal transduction);GO:0016020(membrane);GO:0016042(lipid catabolic process);GO:0016787(hydrolase activity);GO:0019369(arachidonic acid metabolic process);GO:0019433(triglyceride catabolic process);GO:0019898(extrinsic component of membrane);GO:0036155(acylglycerol acyl-chain remodeling);GO:0042803(protein homodimerization activity);GO:0046464(acylglycerol catabolic process);GO:0047372(acylglycerol lipase activity);GO:0050727(regulation of inflammatory response);GO:0051930(regulation of sensory perception of pain);GO:0052689(carboxylic ester hydrolase activity);GO:2000124(regulation of endocannabinoid signaling pathway)","00561(Glycerolipid metabolism);04714(Thermogenesis);04723(Retrograde endocannabinoid signaling);04923(Regulation of lipolysis in adipocytes)","K01054","EC:3.1.1.23","monoglyceride lipase [Source:HGNC Symbol;Acc:HGNC:17038]",{"v":3.73396,"d":"3.73"},{"v":1.151649,"d":"1.15"},{"v":0.623419,"d":"0.62"},{"v":14.472661,"d":"14.47"},{"v":14.944265,"d":"14.94"},{"v":7.346197,"d":"7.35"},{"v":0.149852013388525,"d":"0.15"},{"v":-2.73838962707774,"d":"-2.74"},{"v":0.00137119395241974,"d":"0.00"},{"v":0.0843932060603461,"d":"0.08"},"down","yes"]
[201663,0,"chrX","-",15345596,15384413,"ENST00000297904",7,2069,"ENSG00000165197","VEGFD","GO:0001525(angiogenesis);GO:0001666(response to hypoxia);GO:0001934(positive regulation of protein phosphorylation);GO:0001938(positive regulation of endothelial cell proliferation);GO:0002040(sprouting angiogenesis);GO:0002576(platelet degranulation);GO:0005161(platelet-derived growth factor receptor binding);GO:0005172(vascular endothelial growth factor receptor binding);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0005615(extracellular space);GO:0007275(multicellular organism development);GO:0008083(growth factor activity);GO:0008283(cell population proliferation);GO:0008284(positive regulation of cell population proliferation);GO:0009617(response to bacterium);GO:0010469(regulation of signaling receptor activity);GO:0016020(membrane);GO:0030154(cell differentiation);GO:0031093(platelet alpha granule lumen);GO:0038084(vascular endothelial growth factor signaling pathway);GO:0042056(chemoattractant activity);GO:0042803(protein homodimerization activity);GO:0043185(vascular endothelial growth factor receptor 3 binding);GO:0045766(positive regulation of angiogenesis);GO:0048010(vascular endothelial growth factor receptor signaling pathway);GO:0050918(positive chemotaxis);GO:0050930(induction of positive chemotaxis);GO:0051781(positive regulation of cell division);GO:0060754(positive regulation of mast cell chemotaxis);GO:0071542(dopaminergic neuron differentiation)","04010(MAPK signaling pathway);04014(Ras signaling pathway);04015(Rap1 signaling pathway);04151(PI3K-Akt signaling pathway);04510(Focal adhesion);04926(Relaxin signaling pathway);04933(AGE-RAGE signaling pathway in diabetic complications);05200(Pathways in cancer)","K05449","NA","vascular endothelial growth factor D [Source:HGNC Symbol;Acc:HGNC:3708]",{"v":1.586009,"d":"1.59"},{"v":1.32032,"d":"1.32"},{"v":1.79106,"d":"1.79"},{"v":0.135899,"d":"0.14"},{"v":0.100293,"d":"0.10"},{"v":0.166047,"d":"0.17"},{"v":11.6781043111185,"d":"11.68"},{"v":3.54573419762305,"d":"3.55"},{"v":0.00137287048669597,"d":"0.00"},{"v":0.0843932060603461,"d":"0.08"},"up","yes"]
[2966,0,"chr1","+",25430858,25500205,"ENST00000399766",9,3294,"ENSG00000204178","MACO1","GO:0003674(molecular_function);GO:0005634(nucleus);GO:0005783(endoplasmic reticulum);GO:0007420(brain development);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0023041(neuronal signal transduction);GO:0030424(axon);GO:0030867(rough endoplasmic reticulum membrane);GO:0031965(nuclear membrane);GO:0042995(cell projection);GO:0043005(neuron projection);GO:0044306(neuron projection terminus);GO:0045202(synapse)","NA","NA","NA","macoilin 1 [Source:HGNC Symbol;Acc:HGNC:25572]",{"v":0.595682,"d":"0.60"},{"v":0.629231,"d":"0.63"},{"v":0.448559,"d":"0.45"},0,0,{"v":0.033041,"d":"0.03"},{"v":50.6483459943706,"d":"50.65"},{"v":5.66244325108689,"d":"5.66"},{"v":0.00137971071660309,"d":"0.00"},{"v":0.0844311161144561,"d":"0.08"},"up","yes"]
[66045,0,"chr15","-",72199029,72231386,"ENST00000389093",10,2279,"ENSG00000067225","PKM","GO:0000166(nucleotide binding);GO:0000287(magnesium ion binding);GO:0001666(response to hypoxia);GO:0001889(liver development);GO:0003723(RNA binding);GO:0003824(catalytic activity);GO:0004743(pyruvate kinase activity);GO:0005515(protein binding);GO:0005524(ATP binding);GO:0005576(extracellular region);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005739(mitochondrion);GO:0005829(cytosol);GO:0005929(cilium);GO:0006006(glucose metabolic process);GO:0006096(glycolytic process);GO:0006754(ATP biosynthetic process);GO:0007584(response to nutrient);GO:0008152(metabolic process);GO:0009629(response to gravity);GO:0010033(response to organic substance);GO:0012501(programmed cell death);GO:0014870(response to muscle inactivity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0016740(transferase activity);GO:0023026(MHC class II protein complex binding);GO:0030955(potassium ion binding);GO:0031100(animal organ regeneration);GO:0031982(vesicle);GO:0032868(response to insulin);GO:0032869(cellular response to insulin stimulus);GO:0034774(secretory granule lumen);GO:0042802(identical protein binding);GO:0042866(pyruvate biosynthetic process);GO:0043312(neutrophil degranulation);GO:0043403(skeletal muscle tissue regeneration);GO:0043531(ADP binding);GO:0045296(cadherin binding);GO:0046872(metal ion binding);GO:0051289(protein homotetramerization);GO:0061621(canonical glycolysis);GO:0062023(collagen-containing extracellular matrix);GO:0070062(extracellular exosome);GO:0070324(thyroid hormone binding);GO:1902912(pyruvate kinase complex);GO:1903561(extracellular vesicle);GO:1903672(positive regulation of sprouting angiogenesis);GO:1904813(ficolin-1-rich granule lumen)","00010(Glycolysis / Gluconeogenesis);00230(Purine metabolism);00620(Pyruvate metabolism);04922(Glucagon signaling pathway);04930(Type II diabetes mellitus);05165(Human papillomavirus infection);05203(Viral carcinogenesis);05230(Central carbon metabolism in cancer)","K00873","EC:2.7.1.40","pyruvate kinase M1/2 [Source:HGNC Symbol;Acc:HGNC:9021]",{"v":0.054172,"d":"0.05"},{"v":9.594499,"d":"9.59"},{"v":1.922698,"d":"1.92"},{"v":144.137177,"d":"144.14"},{"v":34.834072,"d":"34.83"},{"v":19.991472,"d":"19.99"},{"v":0.0581584778386701,"d":"0.06"},{"v":-4.10386667917161,"d":"-4.10"},{"v":0.00138003863983231,"d":"0.00"},{"v":0.0844311161144561,"d":"0.08"},"down","yes"]
[9551,0,"chr1","-",112523514,112619141,"ENST00000358039",15,4255,"ENSG00000007341","ST7L","GO:0005515(protein binding);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0030308(negative regulation of cell growth)","NA","NA","NA","suppression of tumorigenicity 7 like [Source:HGNC Symbol;Acc:HGNC:18441]",{"v":0.450038,"d":"0.45"},{"v":0.592815,"d":"0.59"},{"v":0.431271,"d":"0.43"},{"v":0.000791,"d":"0.00"},{"v":0.031609,"d":"0.03"},{"v":0.049632,"d":"0.05"},{"v":17.970109225668,"d":"17.97"},{"v":4.1675272727308,"d":"4.17"},{"v":0.00138045920649565,"d":"0.00"},{"v":0.0844311161144561,"d":"0.08"},"up","yes"]
[9414,0,"chr1","+",111143482,111185102,"ENST00000478042",9,2175,"ENSG00000134255","CEPT1","GO:0004142(diacylglycerol cholinephosphotransferase activity);GO:0004307(ethanolaminephosphotransferase activity);GO:0005634(nucleus);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005794(Golgi apparatus);GO:0006629(lipid metabolic process);GO:0006646(phosphatidylethanolamine biosynthetic process);GO:0006656(phosphatidylcholine biosynthetic process);GO:0006657(CDP-choline pathway);GO:0008654(phospholipid biosynthetic process);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016740(transferase activity);GO:0016780(phosphotransferase activity, for other substituted phosphate groups);GO:0031965(nuclear membrane);GO:0046872(metal ion binding)","00440(Phosphonate and phosphinate metabolism);00564(Glycerophospholipid metabolism);00565(Ether lipid metabolism)","K13644","2.7.8.2;EC:2.7.8.1","choline/ethanolamine phosphotransferase 1 [Source:HGNC Symbol;Acc:HGNC:24289]",{"v":0.456533,"d":"0.46"},{"v":0.525947,"d":"0.53"},0,0,0,0,"inf","inf",{"v":0.00139442748009958,"d":"0.00"},{"v":0.0851117193499207,"d":"0.09"},"up","yes"]
[5546,0,"chr1","-",44821938,44843253,"ENST00000372192",22,4410,"ENSG00000117425","PTCH2","GO:0001558(regulation of cell growth);GO:0001709(cell fate determination);GO:0005119(smoothened binding);GO:0005886(plasma membrane);GO:0007224(smoothened signaling pathway);GO:0008158(hedgehog receptor activity);GO:0008544(epidermis development);GO:0009957(epidermal cell fate specification);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0042633(hair cycle);GO:0043588(skin development);GO:0045606(positive regulation of epidermal cell differentiation);GO:0045879(negative regulation of smoothened signaling pathway);GO:0097108(hedgehog family protein binding)","04340(Hedgehog signaling pathway);05200(Pathways in cancer);05217(Basal cell carcinoma)","K11101","NA","patched 2 [Source:HGNC Symbol;Acc:HGNC:9586]",0,0,0,{"v":0.211964,"d":"0.21"},0,{"v":0.231295,"d":"0.23"},"-inf","-inf",{"v":0.00139627263233011,"d":"0.00"},{"v":0.0851117193499207,"d":"0.09"},"down","yes"]
[98998,0,"chr19","+",11021748,11062030,"ENST00000642508",18,2612,"ENSG00000127616","SMARCA4","GO:0000122(negative regulation of transcription by RNA polymerase II);GO:0000166(nucleotide binding);GO:0000790(nuclear chromatin);GO:0000978(RNA polymerase II proximal promoter sequence-specific DNA binding);GO:0000980(RNA polymerase II distal enhancer sequence-specific DNA binding);GO:0001164(RNA polymerase I CORE element sequence-specific DNA binding);GO:0001188(RNA polymerase I preinitiation complex assembly);GO:0002039(p53 binding);GO:0003407(neural retina development);GO:0003713(transcription coactivator activity);GO:0003714(transcription corepressor activity);GO:0003723(RNA binding);GO:0004386(helicase activity);GO:0005515(protein binding);GO:0005524(ATP binding);GO:0005615(extracellular space);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005730(nucleolus);GO:0006325(chromatin organization);GO:0006337(nucleosome disassembly);GO:0006338(chromatin remodeling);GO:0006355(regulation of transcription, DNA-templated);GO:0006357(regulation of transcription by RNA polymerase II);GO:0007399(nervous system development);GO:0008094(DNA-dependent ATPase activity);GO:0008134(transcription factor binding);GO:0016020(membrane);GO:0016514(SWI/SNF complex);GO:0016787(hydrolase activity);GO:0016817(hydrolase activity, acting on acid anhydrides);GO:0016887(ATPase activity);GO:0030177(positive regulation of Wnt signaling pathway);GO:0030308(negative regulation of cell growth);GO:0030957(Tat protein binding);GO:0031492(nucleosomal DNA binding);GO:0032991(protein-containing complex);GO:0038111(interleukin-7-mediated signaling pathway);GO:0042393(histone binding);GO:0043044(ATP-dependent chromatin remodeling);GO:0043923(positive regulation by host of viral transcription);GO:0045892(negative regulation of transcription, DNA-templated);GO:0045893(positive regulation of transcription, DNA-templated);GO:0045944(positive regulation of transcription by RNA polymerase II);GO:0047485(protein N-terminus binding);GO:0050681(androgen receptor binding);GO:0051091(positive regulation of DNA-binding transcription factor activity);GO:0060766(negative regulation of androgen receptor signaling pathway);GO:0070182(DNA polymerase binding);GO:0070577(lysine-acetylated histone binding);GO:0071564(npBAF complex);GO:0071565(nBAF complex);GO:1901838(positive regulation of transcription of nucleolar large rRNA by RNA polymerase I);GO:1902661(positive regulation of glucose mediated signaling pathway);GO:1902895(positive regulation of pri-miRNA transcription by RNA polymerase II);GO:1904837(beta-catenin-TCF complex assembly)","04714(Thermogenesis);05225(Hepatocellular carcinoma)","NA","NA","SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 [Source:HGNC Symbol;Acc:HGNC:11100]",{"v":0.333668,"d":"0.33"},{"v":0.485473,"d":"0.49"},0,0,0,0,"inf","inf",{"v":0.00139945759902141,"d":"0.00"},{"v":0.0851629724831622,"d":"0.09"},"up","yes"]
[66417,0,"chr15","+",74615839,74625967,"ENST00000568139",7,918,"ENSG00000179335","CLK3","GO:0000166(nucleotide binding);GO:0001669(acrosomal vesicle);GO:0003723(RNA binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0004712(protein serine/threonine/tyrosine kinase activity);GO:0004713(protein tyrosine kinase activity);GO:0005515(protein binding);GO:0005524(ATP binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0006468(protein phosphorylation);GO:0016020(membrane);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0016607(nuclear speck);GO:0016740(transferase activity);GO:0018108(peptidyl-tyrosine phosphorylation);GO:0031410(cytoplasmic vesicle);GO:0042802(identical protein binding);GO:0043484(regulation of RNA splicing);GO:0045111(intermediate filament cytoskeleton);GO:0046777(protein autophosphorylation)","NA","K08823","EC:2.7.12.1","CDC like kinase 3 [Source:HGNC Symbol;Acc:HGNC:2071]",0,{"v":1.959734,"d":"1.96"},{"v":2.588483,"d":"2.59"},{"v":0.007191,"d":"0.01"},0,{"v":0.002741,"d":"0.00"},{"v":457.935662505034,"d":"457.94"},{"v":8.83900111144861,"d":"8.84"},{"v":0.00140409038326166,"d":"0.00"},{"v":0.0853020127489901,"d":"0.09"},"up","yes"]
[35654,0,"chr11","+",102110461,102233423,"ENST00000345877",8,5284,"ENSG00000137693","YAP1","GO:0000902(cell morphogenesis);GO:0000978(RNA polymerase II proximal promoter sequence-specific DNA binding);GO:0001570(vasculogenesis);GO:0001894(tissue homeostasis);GO:0003015(heart process);GO:0003143(embryonic heart tube morphogenesis);GO:0003682(chromatin binding);GO:0003713(transcription coactivator activity);GO:0003714(transcription corepressor activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005667(transcription factor complex);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0006367(transcription initiation from RNA polymerase II promoter);GO:0006974(cellular response to DNA damage stimulus);GO:0008022(protein C-terminus binding);GO:0008134(transcription factor binding);GO:0008283(cell population proliferation);GO:0008284(positive regulation of cell population proliferation);GO:0010468(regulation of gene expression);GO:0010837(regulation of keratinocyte proliferation);GO:0016020(membrane);GO:0030216(keratinocyte differentiation);GO:0030857(negative regulation of epithelial cell differentiation);GO:0030903(notochord development);GO:0032570(response to progesterone);GO:0033148(positive regulation of intracellular estrogen receptor signaling pathway);GO:0033613(activating transcription factor binding);GO:0035019(somatic stem cell population maintenance);GO:0035329(hippo signaling);GO:0042127(regulation of cell population proliferation);GO:0044212(transcription regulatory region DNA binding);GO:0045893(positive regulation of transcription, DNA-templated);GO:0045944(positive regulation of transcription by RNA polymerase II);GO:0046622(positive regulation of organ growth);GO:0046982(protein heterodimerization activity);GO:0048339(paraxial mesoderm development);GO:0048368(lateral mesoderm development);GO:0050767(regulation of neurogenesis);GO:0050847(progesterone receptor signaling pathway);GO:0060045(positive regulation of cardiac muscle cell proliferation);GO:0060242(contact inhibition);GO:0060449(bud elongation involved in lung branching);GO:0060487(lung epithelial cell differentiation);GO:0060828(regulation of canonical Wnt signaling pathway);GO:0061026(cardiac muscle tissue regeneration);GO:0065003(protein-containing complex assembly);GO:0070064(proline-rich region binding);GO:0071148(TEAD-1-YAP complex);GO:0071149(TEAD-2-YAP complex);GO:0071300(cellular response to retinoic acid);GO:0071480(cellular response to gamma radiation);GO:0072091(regulation of stem cell proliferation);GO:0072307(regulation of metanephric nephron tubule epithelial cell differentiation);GO:0090263(positive regulation of canonical Wnt signaling pathway);GO:1902036(regulation of hematopoietic stem cell differentiation);GO:1902459(positive regulation of stem cell population maintenance);GO:1903507(negative regulation of nucleic acid-templated transcription);GO:2000737(negative regulation of stem cell differentiation);GO:2001237(negative regulation of extrinsic apoptotic signaling pathway)","04390(Hippo signaling pathway);04392(Hippo signaling pathway - multiple species)","K16687","NA","Yes associated protein 1 [Source:HGNC Symbol;Acc:HGNC:16262]",{"v":2.002902,"d":"2.00"},{"v":2.295581,"d":"2.30"},{"v":0.509511,"d":"0.51"},{"v":35.00235,"d":"35.00"},{"v":35.477306,"d":"35.48"},{"v":0.252686,"d":"0.25"},{"v":0.0679744776441871,"d":"0.07"},{"v":-3.87886302999819,"d":"-3.88"},{"v":0.00145271803750183,"d":"0.00"},{"v":0.0880005173606557,"d":"0.09"},"down","yes"]
[201489,0,"chrX","+",11759633,11775753,"ENST00000649785",12,2296,"ENSG00000005302","MSL3","GO:0000123(histone acetyltransferase complex);GO:0003677(DNA binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0006325(chromatin organization);GO:0006342(chromatin silencing);GO:0006355(regulation of transcription, DNA-templated);GO:0016573(histone acetylation);GO:0016575(histone deacetylation);GO:0035064(methylated histone binding);GO:0035267(NuA4 histone acetyltransferase complex);GO:0043967(histone H4 acetylation);GO:0043968(histone H2A acetylation);GO:0043984(histone H4-K16 acetylation);GO:0072487(MSL complex)","NA","K18403","NA","MSL complex subunit 3 [Source:HGNC Symbol;Acc:HGNC:7370]",0,{"v":0.44769,"d":"0.45"},{"v":0.462374,"d":"0.46"},0,0,0,"inf","inf",{"v":0.00145366862651447,"d":"0.00"},{"v":0.0880005173606557,"d":"0.09"},"up","yes"]
[200069,0,"chr9","-",131523801,131531259,"ENST00000372208",6,2063,"ENSG00000130717","UCK1","GO:0000166(nucleotide binding);GO:0004849(uridine kinase activity);GO:0005524(ATP binding);GO:0005829(cytosol);GO:0009165(nucleotide biosynthetic process);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0016740(transferase activity);GO:0019206(nucleoside kinase activity);GO:0043097(pyrimidine nucleoside salvage);GO:0044206(UMP salvage);GO:0044211(CTP salvage)","00240(Pyrimidine metabolism);00983(Drug metabolism - other enzymes)","K00876","EC:2.7.1.48","uridine-cytidine kinase 1 [Source:HGNC Symbol;Acc:HGNC:14859]",{"v":0.497393,"d":"0.50"},0,{"v":0.510065,"d":"0.51"},0,0,0,"inf","inf",{"v":0.00145807011469068,"d":"0.00"},{"v":0.0880005173606557,"d":"0.09"},"up","yes"]
[57080,0,"chr14","+",58298556,58372226,"ENST00000395168",24,4051,"ENSG00000032219","ARID4A","GO:0000981(DNA-binding transcription factor activity, RNA polymerase II-specific);GO:0003677(DNA binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0006325(chromatin organization);GO:0006349(regulation of gene expression by genetic imprinting);GO:0006357(regulation of transcription by RNA polymerase II);GO:0007283(spermatogenesis);GO:0017053(transcriptional repressor complex);GO:0030154(cell differentiation);GO:0034773(histone H4-K20 trimethylation);GO:0036124(histone H3-K9 trimethylation);GO:0044212(transcription regulatory region DNA binding);GO:0045892(negative regulation of transcription, DNA-templated);GO:0045944(positive regulation of transcription by RNA polymerase II);GO:0048821(erythrocyte development);GO:0080182(histone H3-K4 trimethylation);GO:0097368(establishment of Sertoli cell barrier)","NA","NA","NA","AT-rich interaction domain 4A [Source:HGNC Symbol;Acc:HGNC:9885]",0,0,0,0,{"v":0.265775,"d":"0.27"},{"v":0.235836,"d":"0.24"},"-inf","-inf",{"v":0.00145819739749834,"d":"0.00"},{"v":0.0880005173606557,"d":"0.09"},"down","yes"]
[22794,0,"chr10","-",87203875,87342542,"ENST00000451940",6,662,"ENSG00000223482","NUTM2A-AS1","NA","NA","NA","NA","NUTM2A antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:45161]",{"v":4.603689,"d":"4.60"},0,{"v":4.4596,"d":"4.46"},{"v":0.035678,"d":"0.04"},0,{"v":0.020108,"d":"0.02"},{"v":162.46529595239,"d":"162.47"},{"v":7.34398776819628,"d":"7.34"},{"v":0.00146892296769527,"d":"0.00"},{"v":0.0884688952613791,"d":"0.09"},"up","yes"]
[7141,0,"chr1","+",65792895,66374574,"ENST00000341517",17,4531,"ENSG00000184588","PDE4B","GO:0000930(gamma-tubulin complex);GO:0001780(neutrophil homeostasis);GO:0004114(3',5'-cyclic-nucleotide phosphodiesterase activity);GO:0004115(3',5'-cyclic-AMP phosphodiesterase activity);GO:0005515(protein binding);GO:0005813(centrosome);GO:0005829(cytosol);GO:0005891(voltage-gated calcium channel complex);GO:0006198(cAMP catabolic process);GO:0007165(signal transduction);GO:0007186(G protein-coupled receptor signaling pathway);GO:0008021(synaptic vesicle);GO:0008081(phosphoric diester hydrolase activity);GO:0014069(postsynaptic density);GO:0016020(membrane);GO:0016787(hydrolase activity);GO:0030018(Z disc);GO:0030552(cAMP binding);GO:0030593(neutrophil chemotaxis);GO:0032729(positive regulation of interferon-gamma production);GO:0032743(positive regulation of interleukin-2 production);GO:0035690(cellular response to drug);GO:0043015(gamma-tubulin binding);GO:0043197(dendritic spine);GO:0044325(ion channel binding);GO:0046872(metal ion binding);GO:0050852(T cell receptor signaling pathway);GO:0050900(leukocyte migration);GO:0060076(excitatory synapse);GO:0071222(cellular response to lipopolysaccharide);GO:0071872(cellular response to epinephrine stimulus);GO:0071944(cell periphery);GO:0086004(regulation of cardiac muscle cell contraction);GO:1901841(regulation of high voltage-gated calcium channel activity);GO:1901898(negative regulation of relaxation of cardiac muscle)","00230(Purine metabolism);04024(cAMP signaling pathway);04928(Parathyroid hormone synthesis, secretion and action);05032(Morphine addiction)","NA","NA","phosphodiesterase 4B [Source:HGNC Symbol;Acc:HGNC:8781]",0,0,{"v":0.033663,"d":"0.03"},{"v":0.417712,"d":"0.42"},{"v":0.405487,"d":"0.41"},{"v":0.521379,"d":"0.52"},{"v":0.0250361079833226,"d":"0.03"},{"v":-5.31984588587398,"d":"-5.32"},{"v":0.00147082886699348,"d":"0.00"},{"v":0.0884688952613791,"d":"0.09"},"down","yes"]
[131882,0,"chr22","-",19894258,19941804,"ENST00000334363",12,1893,"ENSG00000184470","TXNRD2","GO:0000305(response to oxygen radical);GO:0004791(thioredoxin-disulfide reductase activity);GO:0005515(protein binding);GO:0005623(cell);GO:0005737(cytoplasm);GO:0005739(mitochondrion);GO:0005759(mitochondrial matrix);GO:0005829(cytosol);GO:0009055(electron transfer activity);GO:0016491(oxidoreductase activity);GO:0016668(oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor);GO:0022900(electron transport chain);GO:0034599(cellular response to oxidative stress);GO:0045454(cell redox homeostasis);GO:0050660(flavin adenine dinucleotide binding);GO:0055114(oxidation-reduction process);GO:0098869(cellular oxidant detoxification)","00450(Selenocompound metabolism);05200(Pathways in cancer);05225(Hepatocellular carcinoma)","K22182","EC:1.8.1.9","thioredoxin reductase 2 [Source:HGNC Symbol;Acc:HGNC:18155]",0,0,0,{"v":0.47414,"d":"0.47"},{"v":0.578915,"d":"0.58"},0,"-inf","-inf",{"v":0.00150170282778459,"d":"0.00"},{"v":0.0901766342701062,"d":"0.09"},"down","yes"]
[116236,0,"chr2","-",110642114,110678028,"ENST00000466333",20,2501,"ENSG00000169679","BUB1","GO:0000166(nucleotide binding);GO:0000775(chromosome, centromeric region);GO:0000776(kinetochore);GO:0000777(condensed chromosome kinetochore);GO:0000778(condensed nuclear chromosome kinetochore);GO:0000942(condensed nuclear chromosome outer kinetochore);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005515(protein binding);GO:0005524(ATP binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005694(chromosome);GO:0005829(cytosol);GO:0006468(protein phosphorylation);GO:0006915(apoptotic process);GO:0007049(cell cycle);GO:0007059(chromosome segregation);GO:0007063(regulation of sister chromatid cohesion);GO:0007093(mitotic cell cycle checkpoint);GO:0007094(mitotic spindle assembly checkpoint);GO:0008283(cell population proliferation);GO:0016020(membrane);GO:0016032(viral process);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0016740(transferase activity);GO:0051301(cell division);GO:0051754(meiotic sister chromatid cohesion, centromeric);GO:0051983(regulation of chromosome segregation)","04110(Cell cycle);04114(Oocyte meiosis);04914(Progesterone-mediated oocyte maturation)","NA","NA","BUB1 mitotic checkpoint serine/threonine kinase [Source:HGNC Symbol;Acc:HGNC:1148]",0,0,{"v":0.084929,"d":"0.08"},{"v":1.345171,"d":"1.35"},{"v":0.867408,"d":"0.87"},{"v":0.973671,"d":"0.97"},{"v":0.0266548450372695,"d":"0.03"},{"v":-5.22945839502941,"d":"-5.23"},{"v":0.00150497361970658,"d":"0.00"},{"v":0.090223913537855,"d":"0.09"},"down","yes"]
[193532,0,"chr8","-",143612618,143617482,"ENST00000529064",11,1324,"ENSG00000104522","TSTA3","GO:0001913(T cell mediated cytotoxicity);GO:0003824(catalytic activity);GO:0005829(cytosol);GO:0007159(leukocyte cell-cell adhesion);GO:0008152(metabolic process);GO:0009055(electron transfer activity);GO:0009226(nucleotide-sugar biosynthetic process);GO:0016491(oxidoreductase activity);GO:0016853(isomerase activity);GO:0019673(GDP-mannose metabolic process);GO:0022900(electron transport chain);GO:0042351('de novo' GDP-L-fucose biosynthetic process);GO:0042356(GDP-4-dehydro-D-rhamnose reductase activity);GO:0042802(identical protein binding);GO:0047918(GDP-mannose 3,5-epimerase activity);GO:0050577(GDP-L-fucose synthase activity);GO:0050662(coenzyme binding);GO:0055114(oxidation-reduction process);GO:0070062(extracellular exosome)","00051(Fructose and mannose metabolism);00520(Amino sugar and nucleotide sugar metabolism)","K02377","EC:1.1.1.271","tissue specific transplantation antigen P35B [Source:HGNC Symbol;Acc:HGNC:12390]",{"v":1.069775,"d":"1.07"},{"v":1.644953,"d":"1.64"},0,0,0,{"v":0.004129,"d":"0.00"},{"v":657.478324049407,"d":"657.48"},{"v":9.3607995217433,"d":"9.36"},{"v":0.00150864884118787,"d":"0.00"},{"v":0.0902952428341934,"d":"0.09"},"up","yes"]
[146140,0,"chr3","+",161221308,161253532,"ENST00000472947",17,2378,"ENSG00000169251","NMD3","GO:0000055(ribosomal large subunit export from nucleus);GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005730(nucleolus);GO:0005737(cytoplasm);GO:0015031(protein transport);GO:0016020(membrane);GO:0030674(protein binding, bridging);GO:0032092(positive regulation of protein binding);GO:0043023(ribosomal large subunit binding);GO:1902680(positive regulation of RNA biosynthetic process);GO:1904751(positive regulation of protein localization to nucleolus)","03008(Ribosome biogenesis in eukaryotes);03013(RNA transport)","K07562","NA","NMD3 ribosome export adaptor [Source:HGNC Symbol;Acc:HGNC:24250]",{"v":2.656626,"d":"2.66"},{"v":3.162854,"d":"3.16"},{"v":0.079069,"d":"0.08"},{"v":0.089889,"d":"0.09"},{"v":0.04809,"d":"0.05"},{"v":0.116363,"d":"0.12"},{"v":23.1914076322432,"d":"23.19"},{"v":4.53551848375549,"d":"4.54"},{"v":0.00151566493316626,"d":"0.00"},{"v":0.0905659654965959,"d":"0.09"},"up","yes"]
[138524,0,"chr3","+",39383324,39397351,"ENST00000273158",7,2147,"ENSG00000144659","SLC25A38","GO:0005739(mitochondrion);GO:0005743(mitochondrial inner membrane);GO:0006783(heme biosynthetic process);GO:0015187(glycine transmembrane transporter activity);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0022857(transmembrane transporter activity);GO:0030218(erythrocyte differentiation);GO:0055085(transmembrane transport);GO:1904983(glycine import into mitochondrion)","NA","K15118","NA","solute carrier family 25 member 38 [Source:HGNC Symbol;Acc:HGNC:26054]",{"v":4.759629,"d":"4.76"},{"v":8.1458,"d":"8.15"},{"v":0.03319,"d":"0.03"},{"v":0.057851,"d":"0.06"},{"v":0.093072,"d":"0.09"},{"v":0.26671,"d":"0.27"},{"v":30.9808348478209,"d":"30.98"},{"v":4.95330411618021,"d":"4.95"},{"v":0.00152248199791019,"d":"0.00"},{"v":0.0908239260822287,"d":"0.09"},"up","yes"]
[111374,0,"chr2","+",36696866,36814789,"ENST00000379241",14,2525,"ENSG00000205221","VIT","GO:0003429(growth plate cartilage chondrocyte morphogenesis);GO:0005539(glycosaminoglycan binding);GO:0005576(extracellular region);GO:0005614(interstitial matrix);GO:0005615(extracellular space);GO:0007399(nervous system development);GO:0010811(positive regulation of cell-substrate adhesion);GO:0021510(spinal cord development);GO:0030198(extracellular matrix organization);GO:0031012(extracellular matrix);GO:0062023(collagen-containing extracellular matrix)","NA","NA","NA","vitrin [Source:HGNC Symbol;Acc:HGNC:12697]",{"v":0.445102,"d":"0.45"},{"v":0.343891,"d":"0.34"},0,0,0,0,"inf","inf",{"v":0.00152955246478939,"d":"0.00"},{"v":0.0910961328619649,"d":"0.09"},"up","yes"]
[187868,0,"chr8","+",28093102,28190094,"ENST00000523687",13,1923,"ENSG00000134014","ELP3","GO:0000993(RNA polymerase II complex binding);GO:0001764(neuron migration);GO:0002926(tRNA wobble base 5-methoxycarbonylmethyl-2-thiouridinylation);GO:0003824(catalytic activity);GO:0004402(histone acetyltransferase activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005730(nucleolus);GO:0005737(cytoplasm);GO:0006357(regulation of transcription by RNA polymerase II);GO:0006368(transcription elongation from RNA polymerase II promoter);GO:0007399(nervous system development);GO:0007417(central nervous system development);GO:0008023(transcription elongation factor complex);GO:0008607(phosphorylase kinase regulator activity);GO:0016407(acetyltransferase activity);GO:0016573(histone acetylation);GO:0016740(transferase activity);GO:0016746(transferase activity, transferring acyl groups);GO:0030335(positive regulation of cell migration);GO:0033588(Elongator holoenzyme complex);GO:0045859(regulation of protein kinase activity);GO:0046872(metal ion binding);GO:0051536(iron-sulfur cluster binding)","NA","K07739","EC:2.3.1.48","elongator acetyltransferase complex subunit 3 [Source:HGNC Symbol;Acc:HGNC:20696]",{"v":0.524229,"d":"0.52"},{"v":0.504323,"d":"0.50"},0,0,0,0,"inf","inf",{"v":0.00154559439158004,"d":"0.00"},{"v":0.0919008907464856,"d":"0.09"},"up","yes"]
[120805,0,"chr2","-",200870907,200889269,"ENST00000286175",7,1370,"ENSG00000240344","PPIL3","GO:0000398(mRNA splicing, via spliceosome);GO:0000413(protein peptidyl-prolyl isomerization);GO:0003755(peptidyl-prolyl cis-trans isomerase activity);GO:0005515(protein binding);GO:0005681(spliceosomal complex);GO:0006397(mRNA processing);GO:0006457(protein folding);GO:0008380(RNA splicing);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016853(isomerase activity);GO:0071013(catalytic step 2 spliceosome)","NA","K12734","EC:5.2.1.8","peptidylprolyl isomerase like 3 [Source:HGNC Symbol;Acc:HGNC:9262]",{"v":0.086502,"d":"0.09"},{"v":0.197341,"d":"0.20"},{"v":0.205228,"d":"0.21"},{"v":1.478382,"d":"1.48"},{"v":1.235394,"d":"1.24"},{"v":3.172057,"d":"3.17"},{"v":0.0830929114026851,"d":"0.08"},{"v":-3.58913078281998,"d":"-3.59"},{"v":0.00155343248948212,"d":"0.00"},{"v":0.0922160169001394,"d":"0.09"},"down","yes"]
[15583,0,"chr1","+",204073115,204127743,"ENST00000367204",14,4076,"ENSG00000143842","SOX13","GO:0000977(RNA polymerase II regulatory region sequence-specific DNA binding);GO:0000981(DNA-binding transcription factor activity, RNA polymerase II-specific);GO:0003677(DNA binding);GO:0003700(DNA-binding transcription factor activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0006355(regulation of transcription, DNA-templated);GO:0009653(anatomical structure morphogenesis);GO:0043565(sequence-specific DNA binding);GO:0045165(cell fate commitment);GO:0045586(regulation of gamma-delta T cell differentiation);GO:0045892(negative regulation of transcription, DNA-templated);GO:0045944(positive regulation of transcription by RNA polymerase II)","NA","K09269","NA","SRY-box 13 [Source:HGNC Symbol;Acc:HGNC:11192]",{"v":0.804684,"d":"0.80"},{"v":0.75131,"d":"0.75"},{"v":0.14497,"d":"0.14"},{"v":0.052784,"d":"0.05"},{"v":0.042907,"d":"0.04"},{"v":0.021344,"d":"0.02"},{"v":14.5338061263725,"d":"14.53"},{"v":3.86134066162792,"d":"3.86"},{"v":0.00156865001953121,"d":"0.00"},{"v":0.0929674636371432,"d":"0.09"},"up","yes"]
[9434,0,"chr1","+",111227713,111243440,"ENST00000369748",11,1416,"ENSG00000064886","CHI3L2","GO:0005576(extracellular region);GO:0005615(extracellular space);GO:0005975(carbohydrate metabolic process);GO:0008061(chitin binding);GO:0016787(hydrolase activity);GO:0030246(carbohydrate binding)","NA","NA","NA","chitinase 3 like 2 [Source:HGNC Symbol;Acc:HGNC:1933]",{"v":3.236883,"d":"3.24"},{"v":3.661674,"d":"3.66"},{"v":3.371755,"d":"3.37"},0,0,{"v":0.229461,"d":"0.23"},{"v":44.7584208209674,"d":"44.76"},{"v":5.48408723053255,"d":"5.48"},{"v":0.00157906301331728,"d":"0.00"},{"v":0.0934321812277145,"d":"0.09"},"up","yes"]
[76038,0,"chr16","-",66732009,66751594,"ENST00000440564",6,1145,"ENSG00000135720","DYNC1LI2","GO:0000166(nucleotide binding);GO:0000226(microtubule cytoskeleton organization);GO:0000776(kinetochore);GO:0003774(motor activity);GO:0003777(microtubule motor activity);GO:0005524(ATP binding);GO:0005737(cytoplasm);GO:0005764(lysosome);GO:0005770(late endosome);GO:0005813(centrosome);GO:0005829(cytosol);GO:0005856(cytoskeleton);GO:0005868(cytoplasmic dynein complex);GO:0005874(microtubule);GO:0006888(endoplasmic reticulum to Golgi vesicle-mediated transport);GO:0007018(microtubule-based movement);GO:0016020(membrane);GO:0019886(antigen processing and presentation of exogenous peptide antigen via MHC class II);GO:0030286(dynein complex);GO:0045504(dynein heavy chain binding);GO:0051260(protein homooligomerization);GO:0051642(centrosome localization);GO:1990090(cellular response to nerve growth factor stimulus)","04145(Phagosome);04962(Vasopressin-regulated water reabsorption);05132(Salmonella infection)","K10416","NA","dynein cytoplasmic 1 light intermediate chain 2 [Source:HGNC Symbol;Acc:HGNC:2966]",{"v":1.678188,"d":"1.68"},{"v":0.669484,"d":"0.67"},{"v":2.831598,"d":"2.83"},{"v":0.125684,"d":"0.13"},{"v":0.066577,"d":"0.07"},{"v":0.162839,"d":"0.16"},{"v":14.5853843987609,"d":"14.59"},{"v":3.86645150394678,"d":"3.87"},{"v":0.00162963032100967,"d":"0.00"},{"v":0.0962674301825713,"d":"0.10"},"up","yes"]
[110505,0,"chr2","-",25377245,25673647,"ENST00000288642",20,2464,"ENSG00000138101","DTNB","GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0008270(zinc ion binding);GO:0046872(metal ion binding)","NA","NA","NA","dystrobrevin beta [Source:HGNC Symbol;Acc:HGNC:3058]",{"v":0.528732,"d":"0.53"},{"v":0.786611,"d":"0.79"},{"v":0.500096,"d":"0.50"},{"v":0.045124,"d":"0.05"},{"v":0.027199,"d":"0.03"},{"v":0.031978,"d":"0.03"},{"v":17.4057679216882,"d":"17.41"},{"v":4.12149356033487,"d":"4.12"},{"v":0.00163851336382732,"d":"0.00"},{"v":0.0966350495257252,"d":"0.10"},"up","yes"]
[38977,0,"chr12","+",6226328,6238253,"ENST00000646407",7,970,"ENSG00000010278","CD9","GO:0002576(platelet degranulation);GO:0005178(integrin binding);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0005615(extracellular space);GO:0005886(plasma membrane);GO:0005887(integral component of plasma membrane);GO:0005925(focal adhesion);GO:0007155(cell adhesion);GO:0007166(cell surface receptor signaling pathway);GO:0007338(single fertilization);GO:0007342(fusion of sperm to egg plasma membrane involved in single fertilization);GO:0007420(brain development);GO:0008285(negative regulation of cell population proliferation);GO:0009414(response to water deprivation);GO:0009897(external side of plasma membrane);GO:0009986(cell surface);GO:0014003(oligodendrocyte development);GO:0014905(myoblast fusion involved in skeletal muscle regeneration);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016324(apical plasma membrane);GO:0030168(platelet activation);GO:0030666(endocytic vesicle membrane);GO:0030669(clathrin-coated endocytic vesicle membrane);GO:0030913(paranodal junction assembly);GO:0031092(platelet alpha granule membrane);GO:0031623(receptor internalization);GO:0035036(sperm-egg recognition);GO:0051271(negative regulation of cellular component movement);GO:0070062(extracellular exosome);GO:0071404(cellular response to low-density lipoprotein particle stimulus);GO:0090331(negative regulation of platelet aggregation);GO:1903561(extracellular vesicle);GO:1905521(regulation of macrophage migration)","04640(Hematopoietic cell lineage)","NA","NA","CD9 molecule [Source:HGNC Symbol;Acc:HGNC:1709]",{"v":1.712543,"d":"1.71"},0,{"v":1.914168,"d":"1.91"},0,{"v":0.012727,"d":"0.01"},0,{"v":284.961970613656,"d":"284.96"},{"v":8.15462558811212,"d":"8.15"},{"v":0.0016582958648977,"d":"0.00"},{"v":0.0976432557078337,"d":"0.10"},"up","yes"]
[138210,0,"chr3","+",36993798,37050706,"ENST00000455445",19,2296,"ENSG00000076242","MLH1","GO:0000166(nucleotide binding);GO:0000289(nuclear-transcribed mRNA poly(A) tail shortening);GO:0000712(resolution of meiotic recombination intermediates);GO:0000793(condensed chromosome);GO:0000794(condensed nuclear chromosome);GO:0000795(synaptonemal complex);GO:0001673(male germ cell nucleus);GO:0002204(somatic recombination of immunoglobulin genes involved in immune response);GO:0003682(chromatin binding);GO:0003697(single-stranded DNA binding);GO:0005515(protein binding);GO:0005524(ATP binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005694(chromosome);GO:0005712(chiasma);GO:0005715(late recombination nodule);GO:0006281(DNA repair);GO:0006298(mismatch repair);GO:0006303(double-strand break repair via nonhomologous end joining);GO:0006974(cellular response to DNA damage stimulus);GO:0007049(cell cycle);GO:0007060(male meiosis chromosome segregation);GO:0007129(synapsis);GO:0007131(reciprocal meiotic recombination);GO:0007140(male meiotic nuclear division);GO:0007283(spermatogenesis);GO:0008630(intrinsic apoptotic signaling pathway in response to DNA damage);GO:0009617(response to bacterium);GO:0016020(membrane);GO:0016321(female meiosis chromosome segregation);GO:0016446(somatic hypermutation of immunoglobulin genes);GO:0016447(somatic recombination of immunoglobulin gene segments);GO:0016887(ATPase activity);GO:0019899(enzyme binding);GO:0030983(mismatched DNA binding);GO:0032137(guanine/thymine mispair binding);GO:0032300(mismatch repair complex);GO:0032389(MutLalpha complex);GO:0032407(MutSalpha complex binding);GO:0043060(meiotic metaphase I plate congression);GO:0045132(meiotic chromosome segregation);GO:0045141(meiotic telomere clustering);GO:0045143(homologous chromosome segregation);GO:0045190(isotype switching);GO:0045950(negative regulation of mitotic recombination);GO:0048298(positive regulation of isotype switching to IgA isotypes);GO:0048304(positive regulation of isotype switching to IgG isotypes);GO:0048477(oogenesis);GO:0051257(meiotic spindle midzone assembly);GO:0051321(meiotic cell cycle)","01524(Platinum drug resistance);03430(Mismatch repair);03460(Fanconi anemia pathway);05200(Pathways in cancer);05210(Colorectal cancer);05213(Endometrial cancer);05226(Gastric cancer)","K08734","NA","mutL homolog 1 [Source:HGNC Symbol;Acc:HGNC:7127]",{"v":0.426132,"d":"0.43"},{"v":0.384439,"d":"0.38"},0,0,0,0,"inf","inf",{"v":0.00166351258329497,"d":"0.00"},{"v":0.0977919290470977,"d":"0.10"},"up","yes"]
[27508,0,"chr11","+",10305073,10307395,"ENST00000534464",3,1640,"ENSG00000148926","ADM","GO:0001570(vasculogenesis);GO:0001666(response to hypoxia);GO:0001843(neural tube closure);GO:0002026(regulation of the force of heart contraction);GO:0002031(G protein-coupled receptor internalization);GO:0003073(regulation of systemic arterial blood pressure);GO:0005102(signaling receptor binding);GO:0005179(hormone activity);GO:0005576(extracellular region);GO:0005615(extracellular space);GO:0005737(cytoplasm);GO:0006954(inflammatory response);GO:0007165(signal transduction);GO:0007186(G protein-coupled receptor signaling pathway);GO:0007189(adenylate cyclase-activating G protein-coupled receptor signaling pathway);GO:0007204(positive regulation of cytosolic calcium ion concentration);GO:0007507(heart development);GO:0007565(female pregnancy);GO:0007568(aging);GO:0008209(androgen metabolic process);GO:0008284(positive regulation of cell population proliferation);GO:0008285(negative regulation of cell population proliferation);GO:0009409(response to cold);GO:0009611(response to wounding);GO:0010033(response to organic substance);GO:0010460(positive regulation of heart rate);GO:0010469(regulation of signaling receptor activity);GO:0019933(cAMP-mediated signaling);GO:0031100(animal organ regeneration);GO:0031102(neuron projection regeneration);GO:0031623(receptor internalization);GO:0031700(adrenomedullin receptor binding);GO:0032496(response to lipopolysaccharide);GO:0032868(response to insulin);GO:0035809(regulation of urine volume);GO:0042475(odontogenesis of dentin-containing tooth);GO:0042594(response to starvation);GO:0043065(positive regulation of apoptotic process);GO:0043116(negative regulation of vascular permeability);GO:0045766(positive regulation of angiogenesis);GO:0045906(negative regulation of vasoconstriction);GO:0046879(hormone secretion);GO:0048589(developmental growth);GO:0051384(response to glucocorticoid);GO:0055074(calcium ion homeostasis);GO:0060670(branching involved in labyrinthine layer morphogenesis);GO:0060712(spongiotrophoblast layer development);GO:0097084(vascular smooth muscle cell development);GO:0097647(amylin receptor signaling pathway);GO:0097755(positive regulation of blood vessel diameter);GO:1990410(adrenomedullin receptor signaling pathway);GO:2000184(positive regulation of progesterone biosynthetic process);GO:2001214(positive regulation of vasculogenesis)","04080(Neuroactive ligand-receptor interaction);04270(Vascular smooth muscle contraction)","NA","NA","adrenomedullin [Source:HGNC Symbol;Acc:HGNC:259]",{"v":0.826051,"d":"0.83"},{"v":0.724202,"d":"0.72"},{"v":0.592225,"d":"0.59"},{"v":6.630988,"d":"6.63"},{"v":5.969085,"d":"5.97"},{"v":5.954595,"d":"5.95"},{"v":0.115468409351221,"d":"0.12"},{"v":-3.11442989178471,"d":"-3.11"},{"v":0.00166916966787884,"d":"0.00"},{"v":0.0979659677448116,"d":"0.10"},"down","yes"]
[90954,0,"chr17","+",78005056,78108835,"ENST00000301624",20,9632,"ENSG00000078687","TNRC6C","GO:0000932(P-body);GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0005515(protein binding);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0006417(regulation of translation);GO:0007223(Wnt signaling pathway, calcium modulating pathway);GO:0010628(positive regulation of gene expression);GO:0010629(negative regulation of gene expression);GO:0031047(gene silencing by RNA);GO:0035068(micro-ribonucleoprotein complex);GO:0035194(posttranscriptional gene silencing by RNA);GO:0035195(gene silencing by miRNA);GO:0035278(miRNA mediated inhibition of translation);GO:0045652(regulation of megakaryocyte differentiation);GO:0060213(positive regulation of nuclear-transcribed mRNA poly(A) tail shortening);GO:1900153(positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)","NA","K18412","NA","trinucleotide repeat containing 6C [Source:HGNC Symbol;Acc:HGNC:29318]",{"v":0.545605,"d":"0.55"},{"v":0.286248,"d":"0.29"},0,{"v":0.004974,"d":"0.00"},0,0,{"v":167.240249296341,"d":"167.24"},{"v":7.38577828882147,"d":"7.39"},{"v":0.00168592782732063,"d":"0.00"},{"v":0.0987899322041265,"d":"0.10"},"up","yes"]
[73092,0,"chr16","-",28477289,28492044,"ENST00000561689",14,1957,"ENSG00000188603","CLN3","GO:0000139(Golgi membrane);GO:0001508(action potential);GO:0001575(globoside metabolic process);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005739(mitochondrion);GO:0005764(lysosome);GO:0005765(lysosomal membrane);GO:0005768(endosome);GO:0005769(early endosome);GO:0005770(late endosome);GO:0005776(autophagosome);GO:0005783(endoplasmic reticulum);GO:0005794(Golgi apparatus);GO:0005795(Golgi stack);GO:0005802(trans-Golgi network);GO:0005886(plasma membrane);GO:0005901(caveola);GO:0006520(cellular amino acid metabolic process);GO:0006672(ceramide metabolic process);GO:0006678(glucosylceramide metabolic process);GO:0006681(galactosylceramide metabolic process);GO:0006684(sphingomyelin metabolic process);GO:0006898(receptor-mediated endocytosis);GO:0007040(lysosome organization);GO:0007042(lysosomal lumen acidification);GO:0008021(synaptic vesicle);GO:0008306(associative learning);GO:0015809(arginine transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016236(macroautophagy);GO:0016485(protein processing);GO:0030163(protein catabolic process);GO:0030176(integral component of endoplasmic reticulum membrane);GO:0035235(ionotropic glutamate receptor signaling pathway);GO:0035752(lysosomal lumen pH elevation);GO:0042133(neurotransmitter metabolic process);GO:0042987(amyloid precursor protein catabolic process);GO:0043005(neuron projection);GO:0043066(negative regulation of apoptotic process);GO:0043086(negative regulation of catalytic activity);GO:0043524(negative regulation of neuron apoptotic process);GO:0045121(membrane raft);GO:0045861(negative regulation of proteolysis);GO:0047496(vesicle transport along microtubule);GO:0050885(neuromuscular process controlling balance);GO:0051082(unfolded protein binding);GO:0051453(regulation of intracellular pH);GO:0051480(regulation of cytosolic calcium ion concentration);GO:0061024(membrane organization);GO:0097352(autophagosome maturation)","04142(Lysosome)","NA","NA","CLN3, battenin [Source:HGNC Symbol;Acc:HGNC:2074]",{"v":0.145431,"d":"0.15"},{"v":0.029364,"d":"0.03"},{"v":0.00673,"d":"0.01"},{"v":2.434694,"d":"2.43"},{"v":0.25284,"d":"0.25"},{"v":1.180247,"d":"1.18"},{"v":0.0469325952012278,"d":"0.05"},{"v":-4.41326595143236,"d":"-4.41"},{"v":0.00169506352173272,"d":"0.00"},{"v":0.0991653103776969,"d":"0.10"},"down","yes"]
[110146,0,"chr2","-",17663812,17753810,"ENST00000448223",28,5240,"ENSG00000163029","SMC6","GO:0000166(nucleotide binding);GO:0000722(telomere maintenance via recombination);GO:0000724(double-strand break repair via homologous recombination);GO:0000781(chromosome, telomeric region);GO:0000803(sex chromosome);GO:0005515(protein binding);GO:0005524(ATP binding);GO:0005622(intracellular);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005694(chromosome);GO:0006281(DNA repair);GO:0006310(DNA recombination);GO:0006974(cellular response to DNA damage stimulus);GO:0016605(PML body);GO:0016607(nuclear speck);GO:0030915(Smc5-Smc6 complex);GO:0031625(ubiquitin protein ligase binding);GO:0035061(interchromatin granule);GO:0035861(site of double-strand break);GO:0051984(positive regulation of chromosome segregation);GO:0090398(cellular senescence)","NA","K22804","NA","structural maintenance of chromosomes 6 [Source:HGNC Symbol;Acc:HGNC:20466]",{"v":0.130871,"d":"0.13"},{"v":0.024878,"d":"0.02"},{"v":0.008333,"d":"0.01"},{"v":0.006223,"d":"0.01"},{"v":4.078932,"d":"4.08"},{"v":3.019938,"d":"3.02"},{"v":0.0230935752705841,"d":"0.02"},{"v":-5.43636464611931,"d":"-5.44"},{"v":0.00172296995427562,"d":"0.00"},{"v":0.100635849580118,"d":"0.10"},"down","yes"]
[143014,0,"chr3","+",113948065,113962978,"ENST00000478793",7,3466,"ENSG00000184307","ZDHHC23","GO:0003674(molecular_function);GO:0005575(cellular_component);GO:0005783(endoplasmic reticulum);GO:0005794(Golgi apparatus);GO:0006612(protein targeting to membrane);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016740(transferase activity);GO:0016746(transferase activity, transferring acyl groups);GO:0018230(peptidyl-L-cysteine S-palmitoylation);GO:0018345(protein palmitoylation);GO:0019706(protein-cysteine S-palmitoyltransferase activity);GO:0072659(protein localization to plasma membrane)","NA","K18932","EC:2.3.1.225","zinc finger DHHC-type containing 23 [Source:HGNC Symbol;Acc:HGNC:28654]",0,{"v":0.278281,"d":"0.28"},{"v":0.239721,"d":"0.24"},0,0,0,"inf","inf",{"v":0.00174045262787149,"d":"0.00"},{"v":0.101493810546663,"d":"0.10"},"up","yes"]
[53280,0,"chr13","-",108207439,108215535,"ENST00000611712",3,4180,"ENSG00000174405","LIG4","GO:0000012(single strand break repair);GO:0000166(nucleotide binding);GO:0000784(nuclear chromosome, telomeric region);GO:0000793(condensed chromosome);GO:0001701(in utero embryonic development);GO:0002328(pro-B cell differentiation);GO:0003677(DNA binding);GO:0003909(DNA ligase activity);GO:0003910(DNA ligase (ATP) activity);GO:0005515(protein binding);GO:0005524(ATP binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005958(DNA-dependent protein kinase-DNA ligase 4 complex);GO:0006260(DNA replication);GO:0006266(DNA ligation);GO:0006281(DNA repair);GO:0006297(nucleotide-excision repair, DNA gap filling);GO:0006302(double-strand break repair);GO:0006303(double-strand break repair via nonhomologous end joining);GO:0006310(DNA recombination);GO:0006974(cellular response to DNA damage stimulus);GO:0007049(cell cycle);GO:0007417(central nervous system development);GO:0008022(protein C-terminus binding);GO:0008283(cell population proliferation);GO:0010165(response to X-ray);GO:0010212(response to ionizing radiation);GO:0010332(response to gamma radiation);GO:0016874(ligase activity);GO:0032807(DNA ligase IV complex);GO:0033077(T cell differentiation in thymus);GO:0033151(V(D)J recombination);GO:0033152(immunoglobulin V(D)J recombination);GO:0033153(T cell receptor V(D)J recombination);GO:0035019(somatic stem cell population maintenance);GO:0036464(cytoplasmic ribonucleoprotein granule);GO:0043524(negative regulation of neuron apoptotic process);GO:0045190(isotype switching);GO:0046872(metal ion binding);GO:0048146(positive regulation of fibroblast proliferation);GO:0050769(positive regulation of neurogenesis);GO:0051102(DNA ligation involved in DNA recombination);GO:0051103(DNA ligation involved in DNA repair);GO:0051276(chromosome organization);GO:0051301(cell division);GO:0051402(neuron apoptotic process);GO:0070419(nonhomologous end joining complex);GO:0071285(cellular response to lithium ion);GO:0071479(cellular response to ionizing radiation);GO:0071897(DNA biosynthetic process);GO:0075713(establishment of integrated proviral latency);GO:0097680(double-strand break repair via classical nonhomologous end joining);GO:2001252(positive regulation of chromosome organization)","03450(Non-homologous end-joining)","K10777","EC:6.5.1.1","DNA ligase 4 [Source:HGNC Symbol;Acc:HGNC:6601]",{"v":0.051098,"d":"0.05"},{"v":1.45906,"d":"1.46"},{"v":0.317658,"d":"0.32"},{"v":0.030915,"d":"0.03"},{"v":0.033519,"d":"0.03"},{"v":0.002047,"d":"0.00"},{"v":27.4938102615785,"d":"27.49"},{"v":4.78103495315907,"d":"4.78"},{"v":0.00178280891744688,"d":"0.00"},{"v":0.10379719226097,"d":"0.10"},"up","yes"]
[190942,0,"chr8","-",92885349,92966087,"ENST00000517858",6,1882,"ENSG00000205133","TRIQK","GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0016020(membrane);GO:0016021(integral component of membrane)","NA","NA","NA","triple QxxK/R motif containing [Source:HGNC Symbol;Acc:HGNC:27828]",{"v":1.173662,"d":"1.17"},{"v":1.264874,"d":"1.26"},{"v":0.236718,"d":"0.24"},{"v":0.006289,"d":"0.01"},{"v":0.063529,"d":"0.06"},0,{"v":38.3175398894268,"d":"38.32"},{"v":5.25993303322512,"d":"5.26"},{"v":0.00180466934960003,"d":"0.00"},{"v":0.10490181995355,"d":"0.10"},"up","yes"]
[17103,0,"chr1","-",226989865,227318474,"ENST00000366769",36,10855,"ENSG00000143776","CDC42BPA","GO:0000166(nucleotide binding);GO:0000287(magnesium ion binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005515(protein binding);GO:0005524(ATP binding);GO:0005737(cytoplasm);GO:0005911(cell-cell junction);GO:0006468(protein phosphorylation);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0016477(cell migration);GO:0016740(transferase activity);GO:0030027(lamellipodium);GO:0030036(actin cytoskeleton organization);GO:0031032(actomyosin structure organization);GO:0031252(cell leading edge);GO:0031532(actin cytoskeleton reorganization);GO:0035556(intracellular signal transduction);GO:0042641(actomyosin);GO:0042802(identical protein binding);GO:0042995(cell projection);GO:0046872(metal ion binding);GO:0070062(extracellular exosome)","NA","NA","NA","CDC42 binding protein kinase alpha [Source:HGNC Symbol;Acc:HGNC:1737]",{"v":0.895468,"d":"0.90"},{"v":0.908408,"d":"0.91"},{"v":0.3901,"d":"0.39"},{"v":0.862449,"d":"0.86"},{"v":7.257439,"d":"7.26"},{"v":7.186766,"d":"7.19"},{"v":0.143334787602829,"d":"0.14"},{"v":-2.80253929818857,"d":"-2.80"},{"v":0.00180819223501393,"d":"0.00"},{"v":0.104938696322773,"d":"0.10"},"down","yes"]
[68691,0,"chr15","+",98648971,98964530,"ENST00000268035",21,11803,"ENSG00000140443","IGF1R","GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0004713(protein tyrosine kinase activity);GO:0004714(transmembrane receptor protein tyrosine kinase activity);GO:0005009(insulin-activated receptor activity);GO:0005010(insulin-like growth factor-activated receptor activity);GO:0005158(insulin receptor binding);GO:0005515(protein binding);GO:0005520(insulin-like growth factor binding);GO:0005524(ATP binding);GO:0005886(plasma membrane);GO:0005887(integral component of plasma membrane);GO:0005899(insulin receptor complex);GO:0006468(protein phosphorylation);GO:0006955(immune response);GO:0007165(signal transduction);GO:0007169(transmembrane receptor protein tyrosine kinase signaling pathway);GO:0008284(positive regulation of cell population proliferation);GO:0008286(insulin receptor signaling pathway);GO:0014065(phosphatidylinositol 3-kinase signaling);GO:0014068(positive regulation of phosphatidylinositol 3-kinase signaling);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0016740(transferase activity);GO:0018108(peptidyl-tyrosine phosphorylation);GO:0030335(positive regulation of cell migration);GO:0030424(axon);GO:0031994(insulin-like growth factor I binding);GO:0035867(alphav-beta3 integrin-IGF-1-IGF1R complex);GO:0038083(peptidyl-tyrosine autophosphorylation);GO:0042593(glucose homeostasis);GO:0042802(identical protein binding);GO:0043066(negative regulation of apoptotic process);GO:0043231(intracellular membrane-bounded organelle);GO:0043235(receptor complex);GO:0043243(positive regulation of protein complex disassembly);GO:0043410(positive regulation of MAPK cascade);GO:0043548(phosphatidylinositol 3-kinase binding);GO:0043559(insulin binding);GO:0043560(insulin receptor substrate binding);GO:0046328(regulation of JNK cascade);GO:0046777(protein autophosphorylation);GO:0048009(insulin-like growth factor receptor signaling pathway);GO:0048015(phosphatidylinositol-mediated signaling);GO:0048856(anatomical structure development);GO:0051262(protein tetramerization);GO:0051389(inactivation of MAPKK activity);GO:0051897(positive regulation of protein kinase B signaling);GO:0071333(cellular response to glucose stimulus);GO:0097062(dendritic spine maintenance);GO:0097242(amyloid-beta clearance);GO:0120162(positive regulation of cold-induced thermogenesis);GO:1904646(cellular response to amyloid-beta)","01521(EGFR tyrosine kinase inhibitor resistance);01522(Endocrine resistance);04010(MAPK signaling pathway);04014(Ras signaling pathway);04015(Rap1 signaling pathway);04066(HIF-1 signaling pathway);04068(FoxO signaling pathway);04114(Oocyte meiosis);04140(Autophagy - animal);04144(Endocytosis);04150(mTOR signaling pathway);04151(PI3K-Akt signaling pathway);04152(AMPK signaling pathway);04211(Longevity regulating pathway);04213(Longevity regulating pathway - multiple species);04510(Focal adhesion);04520(Adherens junction);04550(Signaling pathways regulating pluripotency of stem cells);04730(Long-term depression);04913(Ovarian steroidogenesis);04914(Progesterone-mediated oocyte maturation);05200(Pathways in cancer);05202(Transcriptional misregulation in cancer);05205(Proteoglycans in cancer);05214(Glioma);05215(Prostate cancer);05218(Melanoma);05224(Breast cancer);05225(Hepatocellular carcinoma)","K05087","EC:2.7.10.1","insulin like growth factor 1 receptor [Source:HGNC Symbol;Acc:HGNC:5465]",{"v":7.6e-5,"d":"0.00"},{"v":0.003978,"d":"0.00"},{"v":0.220959,"d":"0.22"},{"v":1.012978,"d":"1.01"},{"v":2.046488,"d":"2.05"},{"v":2.978131,"d":"2.98"},{"v":0.0372686351871448,"d":"0.04"},{"v":-4.74589420260469,"d":"-4.75"},{"v":0.00188148074847694,"d":"0.00"},{"v":0.109017855808879,"d":"0.11"},"down","yes"]
[177063,0,"chr7","+",18495746,18668843,"ENST00000405010",12,4239,"ENSG00000048052","HDAC9","GO:0000118(histone deacetylase complex);GO:0000122(negative regulation of transcription by RNA polymerase II);GO:0001975(response to amphetamine);GO:0003714(transcription corepressor activity);GO:0004407(histone deacetylase activity);GO:0005080(protein kinase C binding);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005667(transcription factor complex);GO:0005737(cytoplasm);GO:0006325(chromatin organization);GO:0006954(inflammatory response);GO:0007507(heart development);GO:0008134(transcription factor binding);GO:0016575(histone deacetylation);GO:0016787(hydrolase activity);GO:0030182(neuron differentiation);GO:0030183(B cell differentiation);GO:0032041(NAD-dependent histone deacetylase activity (H3-K14 specific));GO:0032869(cellular response to insulin stimulus);GO:0033558(protein deacetylase activity);GO:0034739(histone deacetylase activity (H4-K16 specific));GO:0034983(peptidyl-lysine deacetylation);GO:0035097(histone methyltransferase complex);GO:0042113(B cell activation);GO:0042632(cholesterol homeostasis);GO:0042826(histone deacetylase binding);GO:0045892(negative regulation of transcription, DNA-templated);GO:0046872(metal ion binding);GO:0048742(regulation of skeletal muscle fiber development);GO:0050710(negative regulation of cytokine secretion);GO:0051005(negative regulation of lipoprotein lipase activity);GO:0051153(regulation of striated muscle cell differentiation);GO:0070491(repressing transcription factor binding);GO:0070932(histone H3 deacetylation);GO:0070933(histone H4 deacetylation);GO:0090050(positive regulation of cell migration involved in sprouting angiogenesis);GO:1990678(histone H4-K16 deacetylation)","05034(Alcoholism);05203(Viral carcinogenesis)","K11409","EC:3.5.1.98","histone deacetylase 9 [Source:HGNC Symbol;Acc:HGNC:14065]",{"v":0.014207,"d":"0.01"},0,{"v":0.079076,"d":"0.08"},{"v":0.334379,"d":"0.33"},{"v":0.849314,"d":"0.85"},{"v":1.047166,"d":"1.05"},{"v":0.0418148345547612,"d":"0.04"},{"v":-4.57984133498494,"d":"-4.58"},{"v":0.00189313741405812,"d":"0.00"},{"v":0.109518602313267,"d":"0.11"},"down","yes"]
[193654,0,"chr8","-",143915153,143976734,"ENST00000436759",33,14787,"ENSG00000178209","PLEC","GO:0003723(RNA binding);GO:0003779(actin binding);GO:0005198(structural molecule activity);GO:0005200(structural constituent of cytoskeleton);GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005856(cytoskeleton);GO:0005882(intermediate filament);GO:0005886(plasma membrane);GO:0005903(brush border);GO:0005925(focal adhesion);GO:0007010(cytoskeleton organization);GO:0008092(cytoskeletal protein binding);GO:0008307(structural constituent of muscle);GO:0016020(membrane);GO:0016528(sarcoplasm);GO:0030054(cell junction);GO:0030056(hemidesmosome);GO:0030506(ankyrin binding);GO:0031581(hemidesmosome assembly);GO:0042060(wound healing);GO:0042383(sarcolemma);GO:0043034(costamere);GO:0043292(contractile fiber);GO:0045104(intermediate filament cytoskeleton organization);GO:0045111(intermediate filament cytoskeleton);GO:0045296(cadherin binding);GO:0048471(perinuclear region of cytoplasm);GO:0070062(extracellular exosome)","NA","K10388","NA","plectin [Source:HGNC Symbol;Acc:HGNC:9069]",{"v":0.026977,"d":"0.03"},{"v":5.701015,"d":"5.70"},{"v":0.030841,"d":"0.03"},{"v":0.067368,"d":"0.07"},{"v":0.047162,"d":"0.05"},{"v":0.049005,"d":"0.05"},{"v":35.2146818723821,"d":"35.21"},{"v":5.13810514444097,"d":"5.14"},{"v":0.0019196456967957,"d":"0.00"},{"v":0.110875561469933,"d":"0.11"},"up","yes"]
[21816,0,"chr10","-",71819751,71822205,"ENST00000493143",3,576,"ENSG00000197746","PSAP","GO:0001664(G protein-coupled receptor binding);GO:0002020(protease binding);GO:0002576(platelet degranulation);GO:0003335(corneocyte development);GO:0004565(beta-galactosidase activity);GO:0005515(protein binding);GO:0005543(phospholipid binding);GO:0005576(extracellular region);GO:0005615(extracellular space);GO:0005737(cytoplasm);GO:0005764(lysosome);GO:0005765(lysosomal membrane);GO:0005770(late endosome);GO:0005886(plasma membrane);GO:0006629(lipid metabolic process);GO:0006665(sphingolipid metabolic process);GO:0006683(galactosylceramide catabolic process);GO:0006687(glycosphingolipid metabolic process);GO:0006869(lipid transport);GO:0007041(lysosomal transport);GO:0007186(G protein-coupled receptor signaling pathway);GO:0007193(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway);GO:0007605(sensory perception of sound);GO:0008047(enzyme activator activity);GO:0008289(lipid binding);GO:0010506(regulation of autophagy);GO:0019216(regulation of lipid metabolic process);GO:0035577(azurophil granule membrane);GO:0042552(myelination);GO:0042803(protein homodimerization activity);GO:0043202(lysosomal lumen);GO:0043231(intracellular membrane-bounded organelle);GO:0043312(neutrophil degranulation);GO:0043408(regulation of MAPK cascade);GO:0043410(positive regulation of MAPK cascade);GO:0048589(developmental growth);GO:0050885(neuromuscular process controlling balance);GO:0051345(positive regulation of hydrolase activity);GO:0060073(micturition);GO:0060736(prostate gland growth);GO:0060742(epithelial cell differentiation involved in prostate gland development);GO:0062023(collagen-containing extracellular matrix);GO:0070062(extracellular exosome);GO:0071310(cellular response to organic substance);GO:0090102(cochlea development);GO:0090659(walking behavior);GO:1903206(negative regulation of hydrogen peroxide-induced cell death);GO:1903575(cornified envelope assembly);GO:1905572(ganglioside GM1 transport to membrane);GO:1905573(ganglioside GM1 binding);GO:1905574(ganglioside GM2 binding);GO:1905575(ganglioside GM3 binding);GO:1905576(ganglioside GT1b binding);GO:1905577(ganglioside GP1c binding)","04142(Lysosome)","NA","NA","prosaposin [Source:HGNC Symbol;Acc:HGNC:9498]",{"v":58.309471,"d":"58.31"},{"v":0.860271,"d":"0.86"},{"v":54.631306,"d":"54.63"},{"v":2.919575,"d":"2.92"},{"v":3.092025,"d":"3.09"},{"v":1.446328,"d":"1.45"},{"v":15.2590703476891,"d":"15.26"},{"v":3.93159516416111,"d":"3.93"},{"v":0.00192739698881716,"d":"0.00"},{"v":0.111146559688456,"d":"0.11"},"up","yes"]
[198248,0,"chr9","-",109375694,109451384,"ENST00000412145",21,8765,"ENSG00000070159","PTPN3","GO:0001784(phosphotyrosine residue binding);GO:0004721(phosphoprotein phosphatase activity);GO:0004725(protein tyrosine phosphatase activity);GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0005856(cytoskeleton);GO:0005886(plasma membrane);GO:0006470(protein dephosphorylation);GO:0008092(cytoskeletal protein binding);GO:0009898(cytoplasmic side of plasma membrane);GO:0016020(membrane);GO:0016311(dephosphorylation);GO:0016787(hydrolase activity);GO:0016791(phosphatase activity);GO:0017080(sodium channel regulator activity);GO:0035335(peptidyl-tyrosine dephosphorylation);GO:0042059(negative regulation of epidermal growth factor receptor signaling pathway);GO:0045930(negative regulation of mitotic cell cycle);GO:0051045(negative regulation of membrane protein ectodomain proteolysis);GO:0051117(ATPase binding);GO:0097421(liver regeneration);GO:0098902(regulation of membrane depolarization during action potential);GO:2000649(regulation of sodium ion transmembrane transporter activity)","NA","K18027","EC:3.1.3.48","protein tyrosine phosphatase, non-receptor type 3 [Source:HGNC Symbol;Acc:HGNC:9655]",{"v":0.196473,"d":"0.20"},{"v":0.184732,"d":"0.18"},{"v":0.644206,"d":"0.64"},{"v":0.039835,"d":"0.04"},{"v":0.026751,"d":"0.03"},{"v":0.012719,"d":"0.01"},{"v":12.9299665847046,"d":"12.93"},{"v":3.69264664164085,"d":"3.69"},{"v":0.001969428537842,"d":"0.00"},{"v":0.113390394262757,"d":"0.11"},"up","yes"]
[198463,0,"chr9","-",113386312,113401284,"ENST00000409155",12,3129,"ENSG00000148218","ALAD","GO:0001666(response to hypoxia);GO:0003824(catalytic activity);GO:0004655(porphobilinogen synthase activity);GO:0005576(extracellular region);GO:0005615(extracellular space);GO:0005634(nucleus);GO:0005829(cytosol);GO:0006779(porphyrin-containing compound biosynthetic process);GO:0006782(protoporphyrinogen IX biosynthetic process);GO:0006783(heme biosynthetic process);GO:0006979(response to oxidative stress);GO:0007584(response to nutrient);GO:0008152(metabolic process);GO:0008270(zinc ion binding);GO:0009635(response to herbicide);GO:0009636(response to toxic substance);GO:0009725(response to hormone);GO:0010033(response to organic substance);GO:0010035(response to inorganic substance);GO:0010038(response to metal ion);GO:0010039(response to iron ion);GO:0010043(response to zinc ion);GO:0010044(response to aluminum ion);GO:0010212(response to ionizing radiation);GO:0010266(response to vitamin B1);GO:0010269(response to selenium ion);GO:0010288(response to lead ion);GO:0014070(response to organic cyclic compound);GO:0014823(response to activity);GO:0016829(lyase activity);GO:0031667(response to nutrient levels);GO:0032025(response to cobalt ion);GO:0032496(response to lipopolysaccharide);GO:0033014(tetrapyrrole biosynthetic process);GO:0033197(response to vitamin E);GO:0033273(response to vitamin);GO:0034774(secretory granule lumen);GO:0042493(response to drug);GO:0042802(identical protein binding);GO:0043200(response to amino acid);GO:0043312(neutrophil degranulation);GO:0045471(response to ethanol);GO:0046685(response to arsenic-containing substance);GO:0046686(response to cadmium ion);GO:0046689(response to mercury ion);GO:0046872(metal ion binding);GO:0051260(protein homooligomerization);GO:0051384(response to glucocorticoid);GO:0051597(response to methylmercury);GO:0070062(extracellular exosome);GO:0070541(response to platinum ion);GO:0070542(response to fatty acid);GO:0071284(cellular response to lead ion);GO:0071353(cellular response to interleukin-4);GO:1901799(negative regulation of proteasomal protein catabolic process);GO:1904813(ficolin-1-rich granule lumen);GO:1904854(proteasome core complex binding)","00860(Porphyrin and chlorophyll metabolism)","NA","NA","aminolevulinate dehydratase [Source:HGNC Symbol;Acc:HGNC:395]",{"v":2.753338,"d":"2.75"},{"v":3.122609,"d":"3.12"},{"v":2.342051,"d":"2.34"},{"v":25.44989,"d":"25.45"},{"v":19.495277,"d":"19.50"},{"v":3.986967,"d":"3.99"},{"v":0.167946854719232,"d":"0.17"},{"v":-2.57392331761478,"d":"-2.57"},{"v":0.0019914560020459,"d":"0.00"},{"v":0.114297613419321,"d":"0.11"},"down","yes"]
[28827,0,"chr11","+",32101995,32105531,"ENST00000531345",2,2653,"ENSG00000049449","RCN1","GO:0005509(calcium ion binding);GO:0005515(protein binding);GO:0005783(endoplasmic reticulum);GO:0005788(endoplasmic reticulum lumen);GO:0043687(post-translational protein modification);GO:0044267(cellular protein metabolic process);GO:0046872(metal ion binding)","NA","NA","NA","reticulocalbin 1 [Source:HGNC Symbol;Acc:HGNC:9934]",{"v":7.329026,"d":"7.33"},{"v":5.732331,"d":"5.73"},{"v":5.897206,"d":"5.90"},{"v":138.043396,"d":"138.04"},{"v":8.410452,"d":"8.41"},{"v":11.586104,"d":"11.59"},{"v":0.119960571742011,"d":"0.12"},{"v":-3.05936779154774,"d":"-3.06"},{"v":0.00199433873878899,"d":"0.00"},{"v":0.114297613419321,"d":"0.11"},"down","yes"]
[171817,0,"chr6","-",71407864,71420745,"ENST00000651660",4,9515,"ENSG00000233237","LINC00472","NA","NA","NA","NA","long intergenic non-protein coding RNA 472 [Source:HGNC Symbol;Acc:HGNC:21380]",{"v":0.027802,"d":"0.03"},{"v":0.033591,"d":"0.03"},{"v":0.040159,"d":"0.04"},{"v":0.419204,"d":"0.42"},{"v":0.152935,"d":"0.15"},{"v":0.528783,"d":"0.53"},{"v":0.0922426838595287,"d":"0.09"},{"v":-3.43842170004498,"d":"-3.44"},{"v":0.00199462391708917,"d":"0.00"},{"v":0.114297613419321,"d":"0.11"},"down","yes"]
[72077,0,"chr16","-",18782968,18790334,"ENST00000569365",5,481,"ENSG00000134419","RPS15A","GO:0000184(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay);GO:0003723(RNA binding);GO:0003735(structural constituent of ribosome);GO:0005515(protein binding);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005840(ribosome);GO:0006412(translation);GO:0006413(translational initiation);GO:0006614(SRP-dependent cotranslational protein targeting to membrane);GO:0008284(positive regulation of cell population proliferation);GO:0009615(response to virus);GO:0016020(membrane);GO:0019083(viral transcription);GO:0022627(cytosolic small ribosomal subunit);GO:0045787(positive regulation of cell cycle);GO:0070062(extracellular exosome)","03010(Ribosome)","K02957","NA","ribosomal protein S15a [Source:HGNC Symbol;Acc:HGNC:10389]",{"v":4.031451,"d":"4.03"},{"v":2.39191,"d":"2.39"},{"v":1.481722,"d":"1.48"},{"v":2.484481,"d":"2.48"},{"v":2.636669,"d":"2.64"},{"v":173.175171,"d":"173.18"},{"v":0.0443367701344774,"d":"0.04"},{"v":-4.4953525138567,"d":"-4.50"},{"v":0.00199993839204745,"d":"0.00"},{"v":0.114421672099345,"d":"0.11"},"down","yes"]
[65366,0,"chr15","-",64963027,64981627,"ENST00000559199",7,2059,"ENSG00000090487","SPG21","GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0005768(endosome);GO:0005794(Golgi apparatus);GO:0005829(cytosol);GO:0010008(endosome membrane);GO:0016020(membrane);GO:0030140(trans-Golgi network transport vesicle);GO:0042609(CD4 receptor binding);GO:0043231(intracellular membrane-bounded organelle);GO:0050851(antigen receptor-mediated signaling pathway)","04144(Endocytosis)","K19367","NA","SPG21, maspardin [Source:HGNC Symbol;Acc:HGNC:20373]",{"v":11.702223,"d":"11.70"},{"v":0.715632,"d":"0.72"},{"v":12.514698,"d":"12.51"},{"v":1.023636,"d":"1.02"},{"v":0.454578,"d":"0.45"},{"v":0.604188,"d":"0.60"},{"v":11.9729778400136,"d":"11.97"},{"v":3.58171010938475,"d":"3.58"},{"v":0.00201301913912074,"d":"0.00"},{"v":0.114988970635624,"d":"0.11"},"up","yes"]
[27494,0,"chr11","-",9808912,9839603,"ENST00000530741",7,993,"ENSG00000133812","SBF2","GO:0005085(guanyl-nucleotide exchange factor activity);GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0005768(endosome);GO:0005774(vacuolar membrane);GO:0005829(cytosol);GO:0006914(autophagy);GO:0010008(endosome membrane);GO:0016020(membrane);GO:0017112(Rab guanyl-nucleotide exchange factor activity);GO:0019208(phosphatase regulator activity);GO:0019902(phosphatase binding);GO:0030424(axon);GO:0035091(phosphatidylinositol binding);GO:0042552(myelination);GO:0042995(cell projection);GO:0043087(regulation of GTPase activity);GO:0048471(perinuclear region of cytoplasm);GO:0051262(protein tetramerization)","NA","K18061","NA","SET binding factor 2 [Source:HGNC Symbol;Acc:HGNC:2135]",{"v":1.849488,"d":"1.85"},{"v":1.647962,"d":"1.65"},{"v":0.053291,"d":"0.05"},{"v":0.026326,"d":"0.03"},{"v":0.023127,"d":"0.02"},{"v":0.024271,"d":"0.02"},{"v":48.16262004232,"d":"48.16"},{"v":5.58984197160388,"d":"5.59"},{"v":0.00204583971625654,"d":"0.00"},{"v":0.116680309091994,"d":"0.12"},"up","yes"]
[135268,0,"chr22","-",42583721,42614931,"ENST00000348657",8,3323,"ENSG00000100227","POLDIP3","GO:0000346(transcription export complex);GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0005515(protein binding);GO:0005623(cell);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0006405(RNA export from nucleus);GO:0006406(mRNA export from nucleus);GO:0006417(regulation of translation);GO:0016607(nuclear speck);GO:0016973(poly(A)+ mRNA export from nucleus);GO:0031124(mRNA 3'-end processing);GO:0036464(cytoplasmic ribonucleoprotein granule);GO:0044877(protein-containing complex binding);GO:0045727(positive regulation of translation);GO:0051028(mRNA transport)","NA","K22414","NA","DNA polymerase delta interacting protein 3 [Source:HGNC Symbol;Acc:HGNC:23782]",{"v":0.766438,"d":"0.77"},{"v":1.06755,"d":"1.07"},{"v":0.688055,"d":"0.69"},{"v":11.794471,"d":"11.79"},{"v":8.54862,"d":"8.55"},{"v":1.043344,"d":"1.04"},{"v":0.117927228170567,"d":"0.12"},{"v":-3.0840312348275,"d":"-3.08"},{"v":0.0020518930795763,"d":"0.00"},{"v":0.116842124735121,"d":"0.12"},"down","yes"]
[52112,0,"chr13","-",52412606,52450634,"ENST00000378060",14,4425,"ENSG00000136100","VPS36","GO:0000814(ESCRT II complex);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005764(lysosome);GO:0005768(endosome);GO:0005770(late endosome);GO:0005829(cytosol);GO:0008022(protein C-terminus binding);GO:0008289(lipid binding);GO:0015031(protein transport);GO:0016020(membrane);GO:0016197(endosomal transport);GO:0016236(macroautophagy);GO:0031902(late endosome membrane);GO:0032266(phosphatidylinositol-3-phosphate binding);GO:0032509(endosome transport via multivesicular body sorting pathway);GO:0036258(multivesicular body assembly);GO:0043130(ubiquitin binding);GO:0043328(protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway);GO:0070062(extracellular exosome)","04144(Endocytosis)","K12190","NA","vacuolar protein sorting 36 homolog [Source:HGNC Symbol;Acc:HGNC:20312]",{"v":9.005212,"d":"9.01"},{"v":11.902966,"d":"11.90"},{"v":9.886821,"d":"9.89"},{"v":0.969343,"d":"0.97"},{"v":2.696136,"d":"2.70"},{"v":2.22768,"d":"2.23"},{"v":5.22555033726394,"d":"5.23"},{"v":2.38558298495064,"d":"2.39"},{"v":0.00206236794853029,"d":"0.00"},{"v":0.117254816228647,"d":"0.12"},"up","yes"]
[82835,0,"chr17","-",19770829,19773924,"ENST00000570983",1,3096,"ENSG00000083290","ULK2","GO:0000045(autophagosome assembly);GO:0000166(nucleotide binding);GO:0000407(phagophore assembly site);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005515(protein binding);GO:0005524(ATP binding);GO:0005829(cytosol);GO:0006468(protein phosphorylation);GO:0006914(autophagy);GO:0007165(signal transduction);GO:0007399(nervous system development);GO:0007409(axonogenesis);GO:0010506(regulation of autophagy);GO:0016020(membrane);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0016740(transferase activity);GO:0030659(cytoplasmic vesicle membrane);GO:0031410(cytoplasmic vesicle);GO:0034045(phagophore assembly site membrane);GO:0042594(response to starvation);GO:0046777(protein autophosphorylation);GO:0048671(negative regulation of collateral sprouting);GO:0048675(axon extension);GO:0075044(autophagy of host cells involved in interaction with symbiont)","04136(Autophagy - other);04140(Autophagy - animal);04150(mTOR signaling pathway)","K08269","EC:2.7.11.1","unc-51 like autophagy activating kinase 2 [Source:HGNC Symbol;Acc:HGNC:13480]",{"v":0.000273,"d":"0.00"},{"v":0.518939,"d":"0.52"},{"v":0.330378,"d":"0.33"},{"v":0.000573,"d":"0.00"},{"v":0.000221,"d":"0.00"},{"v":0.000662,"d":"0.00"},{"v":583.509615384615,"d":"583.51"},{"v":9.18861261940641,"d":"9.19"},{"v":0.00208032391373627,"d":"0.00"},{"v":0.118090887165686,"d":"0.12"},"up","yes"]
[31956,0,"chr11","-",64765604,64767617,"ENST00000413725",4,843,"ENSG00000168066","SF1","GO:0000245(spliceosomal complex assembly);GO:0000389(mRNA 3'-splice site recognition);GO:0000398(mRNA splicing, via spliceosome);GO:0003676(nucleic acid binding);GO:0003714(transcription corepressor activity);GO:0003723(RNA binding);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005681(spliceosomal complex);GO:0005840(ribosome);GO:0006397(mRNA processing);GO:0008270(zinc ion binding);GO:0008380(RNA splicing);GO:0016604(nuclear body);GO:0030238(male sex determination);GO:0030575(nuclear body organization);GO:0033327(Leydig cell differentiation);GO:0042802(identical protein binding);GO:0045131(pre-mRNA branch point binding);GO:0046872(metal ion binding);GO:0048662(negative regulation of smooth muscle cell proliferation);GO:0050810(regulation of steroid biosynthetic process);GO:1903507(negative regulation of nucleic acid-templated transcription)","NA","K13095","NA","splicing factor 1 [Source:HGNC Symbol;Acc:HGNC:12950]",{"v":2.210093,"d":"2.21"},{"v":2.018167,"d":"2.02"},{"v":2.27809,"d":"2.28"},{"v":0.179038,"d":"0.18"},{"v":0.045357,"d":"0.05"},{"v":0.190326,"d":"0.19"},{"v":15.6884990150004,"d":"15.69"},{"v":3.97163542506453,"d":"3.97"},{"v":0.00209970994285826,"d":"0.00"},{"v":0.119005401285554,"d":"0.12"},"up","yes"]
[133676,0,"chr22","+",31081320,31104623,"ENST00000489337",20,3560,"ENSG00000183963","SMTN","GO:0003085(negative regulation of systemic arterial blood pressure);GO:0003779(actin binding);GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0005815(microtubule organizing center);GO:0005856(cytoskeleton);GO:0006939(smooth muscle contraction);GO:0007517(muscle organ development);GO:0008307(structural constituent of muscle);GO:0015629(actin cytoskeleton);GO:0030036(actin cytoskeleton organization);GO:0031941(filamentous actin);GO:0060452(positive regulation of cardiac muscle contraction)","NA","NA","NA","smoothelin [Source:HGNC Symbol;Acc:HGNC:11126]",{"v":0.588434,"d":"0.59"},{"v":0.784042,"d":"0.78"},{"v":0.147931,"d":"0.15"},{"v":0.0251,"d":"0.03"},{"v":0.036652,"d":"0.04"},{"v":0.025596,"d":"0.03"},{"v":17.4063172596968,"d":"17.41"},{"v":4.12153909206426,"d":"4.12"},{"v":0.00210860533160777,"d":"0.00"},{"v":0.119323413858739,"d":"0.12"},"up","yes"]
[199113,0,"chr9","+",125747373,125967377,"ENST00000373489",9,2840,"ENSG00000167081","PBX3","GO:0000980(RNA polymerase II distal enhancer sequence-specific DNA binding);GO:0000981(DNA-binding transcription factor activity, RNA polymerase II-specific);GO:0001228(DNA-binding transcription activator activity, RNA polymerase II-specific);GO:0002087(regulation of respiratory gaseous exchange by neurological system process);GO:0003677(DNA binding);GO:0003700(DNA-binding transcription factor activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005667(transcription factor complex);GO:0006355(regulation of transcription, DNA-templated);GO:0007387(anterior compartment pattern formation);GO:0007388(posterior compartment specification);GO:0007585(respiratory gaseous exchange);GO:0008344(adult locomotory behavior);GO:0021516(dorsal spinal cord development);GO:0043565(sequence-specific DNA binding);GO:0045944(positive regulation of transcription by RNA polymerase II);GO:0048666(neuron development)","05202(Transcriptional misregulation in cancer)","K15610","NA","PBX homeobox 3 [Source:HGNC Symbol;Acc:HGNC:8634]",{"v":3.377249,"d":"3.38"},{"v":3.048823,"d":"3.05"},{"v":5.403504,"d":"5.40"},{"v":0.460507,"d":"0.46"},{"v":0.548127,"d":"0.55"},{"v":0.391153,"d":"0.39"},{"v":8.45098289954115,"d":"8.45"},{"v":3.07911914516147,"d":"3.08"},{"v":0.00211527021400592,"d":"0.00"},{"v":0.11951441193598,"d":"0.12"},"up","yes"]
[167138,0,"chr6","-",7881517,7889445,"ENST00000460138",4,2704,"ENSG00000239264","TXNDC5","GO:0005515(protein binding);GO:0005576(extracellular region);GO:0005623(cell);GO:0005783(endoplasmic reticulum);GO:0005788(endoplasmic reticulum lumen);GO:0016853(isomerase activity);GO:0035578(azurophil granule lumen);GO:0043066(negative regulation of apoptotic process);GO:0043202(lysosomal lumen);GO:0043277(apoptotic cell clearance);GO:0043312(neutrophil degranulation);GO:0045454(cell redox homeostasis);GO:0070062(extracellular exosome)","04141(Protein processing in endoplasmic reticulum)","K13984","NA","thioredoxin domain containing 5 [Source:HGNC Symbol;Acc:HGNC:21073]",{"v":0.065296,"d":"0.07"},{"v":59.840015,"d":"59.84"},{"v":0.401539,"d":"0.40"},{"v":0.486012,"d":"0.49"},{"v":0.816279,"d":"0.82"},{"v":0.108762,"d":"0.11"},{"v":42.738897830202,"d":"42.74"},{"v":5.41747779850033,"d":"5.42"},{"v":0.00213049770849948,"d":"0.00"},{"v":0.120056479213397,"d":"0.12"},"up","yes"]
[34160,0,"chr11","+",74171322,74254703,"ENST00000398427",14,2496,"ENSG00000214517","PPME1","GO:0000086(G2/M transition of mitotic cell cycle);GO:0004864(protein phosphatase inhibitor activity);GO:0005515(protein binding);GO:0005654(nucleoplasm);GO:0006482(protein demethylation);GO:0016787(hydrolase activity);GO:0019888(protein phosphatase regulator activity);GO:0019901(protein kinase binding);GO:0019903(protein phosphatase binding);GO:0032515(negative regulation of phosphoprotein phosphatase activity);GO:0043666(regulation of phosphoprotein phosphatase activity);GO:0045296(cadherin binding);GO:0051721(protein phosphatase 2A binding);GO:0051722(protein C-terminal methylesterase activity);GO:0051723(protein methylesterase activity);GO:0052689(carboxylic ester hydrolase activity)","NA","K13617","EC:3.1.1.89","protein phosphatase methylesterase 1 [Source:HGNC Symbol;Acc:HGNC:30178]",{"v":0.001063,"d":"0.00"},{"v":0.066253,"d":"0.07"},{"v":0.000127,"d":"0.00"},{"v":6.384923,"d":"6.38"},0,{"v":0.884035,"d":"0.88"},{"v":0.00927822117007692,"d":"0.01"},{"v":-6.7519360477468,"d":"-6.75"},{"v":0.00213147341295462,"d":"0.00"},{"v":0.120056479213397,"d":"0.12"},"down","yes"]
[110627,0,"chr2","+",26786056,26794589,"ENST00000335756",5,1389,"ENSG00000115163","CENPA","GO:0000132(establishment of mitotic spindle orientation);GO:0000281(mitotic cytokinesis);GO:0000775(chromosome, centromeric region);GO:0000776(kinetochore);GO:0000777(condensed chromosome kinetochore);GO:0000778(condensed nuclear chromosome kinetochore);GO:0000780(condensed nuclear chromosome, centromeric region);GO:0000786(nucleosome);GO:0000788(nuclear nucleosome);GO:0000939(condensed chromosome inner kinetochore);GO:0003677(DNA binding);GO:0003682(chromatin binding);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005694(chromosome);GO:0005829(cytosol);GO:0007049(cell cycle);GO:0016032(viral process);GO:0031492(nucleosomal DNA binding);GO:0031618(nuclear pericentric heterochromatin);GO:0034080(CENP-A containing nucleosome assembly);GO:0046982(protein heterodimerization activity);GO:0051301(cell division);GO:0051382(kinetochore assembly);GO:0071459(protein localization to chromosome, centromeric region)","NA","NA","NA","centromere protein A [Source:HGNC Symbol;Acc:HGNC:1851]",{"v":0.038253,"d":"0.04"},{"v":0.013653,"d":"0.01"},{"v":0.098331,"d":"0.10"},{"v":0.603182,"d":"0.60"},{"v":1.521718,"d":"1.52"},{"v":0.907989,"d":"0.91"},{"v":0.0495359375170011,"d":"0.05"},{"v":-4.33538063294659,"d":"-4.34"},{"v":0.00216064189886406,"d":"0.00"},{"v":0.121511021959336,"d":"0.12"},"down","yes"]
[93558,0,"chr18","+",23503470,23531807,"ENST00000615148",18,1958,"ENSG00000141452","RMC1","GO:0005515(protein binding);GO:0005764(lysosome);GO:0005765(lysosomal membrane);GO:0005768(endosome);GO:0006914(autophagy);GO:0010506(regulation of autophagy);GO:0016020(membrane);GO:0031902(late endosome membrane);GO:0035658(Mon1-Ccz1 complex)","NA","NA","NA","regulator of MON1-CCZ1 [Source:HGNC Symbol;Acc:HGNC:24326]",{"v":0.027176,"d":"0.03"},{"v":0.832179,"d":"0.83"},{"v":0.899137,"d":"0.90"},{"v":0.001586,"d":"0.00"},{"v":0.013302,"d":"0.01"},{"v":0.018446,"d":"0.02"},{"v":52.7537049259015,"d":"52.75"},{"v":5.72120051364607,"d":"5.72"},{"v":0.00219343956413842,"d":"0.00"},{"v":0.123164852187247,"d":"0.12"},"up","yes"]
[94685,0,"chr18","-",49489477,49492433,"ENST00000580387",6,827,"ENSG00000265681","RPL17","GO:0000184(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay);GO:0002181(cytoplasmic translation);GO:0003723(RNA binding);GO:0003735(structural constituent of ribosome);GO:0005515(protein binding);GO:0005622(intracellular);GO:0005634(nucleus);GO:0005829(cytosol);GO:0005840(ribosome);GO:0006412(translation);GO:0006413(translational initiation);GO:0006614(SRP-dependent cotranslational protein targeting to membrane);GO:0015934(large ribosomal subunit);GO:0019083(viral transcription);GO:0022625(cytosolic large ribosomal subunit)","03010(Ribosome)","K02880","NA","ribosomal protein L17 [Source:HGNC Symbol;Acc:HGNC:10307]",{"v":9.903118,"d":"9.90"},{"v":3.098158,"d":"3.10"},{"v":0.504995,"d":"0.50"},{"v":0.380427,"d":"0.38"},{"v":0.168626,"d":"0.17"},{"v":0.238749,"d":"0.24"},{"v":17.1442456353246,"d":"17.14"},{"v":4.09965252047211,"d":"4.10"},{"v":0.00220323023461498,"d":"0.00"},{"v":0.12352369509809,"d":"0.12"},"up","yes"]
[132785,0,"chr22","+",24270837,24417206,"ENST00000651059",19,6282,"ENSG00000100014","SPECC1L","GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0005815(microtubule organizing center);GO:0005819(spindle);GO:0005829(cytosol);GO:0005856(cytoskeleton);GO:0005921(gap junction);GO:0007049(cell cycle);GO:0007155(cell adhesion);GO:0015629(actin cytoskeleton);GO:0030036(actin cytoskeleton organization);GO:0030054(cell junction);GO:0031941(filamentous actin);GO:0051301(cell division)","NA","K23028","NA","sperm antigen with calponin homology and coiled-coil domains 1 like [Source:HGNC Symbol;Acc:HGNC:29022]",{"v":0.043302,"d":"0.04"},{"v":0.158473,"d":"0.16"},{"v":0.013382,"d":"0.01"},{"v":9.386114,"d":"9.39"},{"v":0.016743,"d":"0.02"},{"v":0.133067,"d":"0.13"},{"v":0.0225627846866229,"d":"0.02"},{"v":-5.46991105441146,"d":"-5.47"},{"v":0.00225671347316152,"d":"0.00"},{"v":0.126327273466807,"d":"0.13"},"down","yes"]
[82112,0,"chr17","+",17131666,17185554,"ENST00000584067",18,3195,"ENSG00000133030","MPRIP","GO:0003779(actin binding);GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005856(cytoskeleton);GO:0005925(focal adhesion);GO:0015629(actin cytoskeleton);GO:0045296(cadherin binding)","NA","NA","NA","myosin phosphatase Rho interacting protein [Source:HGNC Symbol;Acc:HGNC:30321]",{"v":0.1889,"d":"0.19"},{"v":0.147063,"d":"0.15"},{"v":0.287703,"d":"0.29"},{"v":5.047131,"d":"5.05"},{"v":0.150321,"d":"0.15"},{"v":4.177449,"d":"4.18"},{"v":0.0665250758381342,"d":"0.07"},{"v":-3.90995793986375,"d":"-3.91"},{"v":0.00230901256531139,"d":"0.00"},{"v":0.128970473335481,"d":"0.13"},"down","yes"]
[121930,0,"chr2","+",218233000,218254108,"ENST00000470146",7,2226,"ENSG00000163466","ARPC2","GO:0003779(actin binding);GO:0005200(structural constituent of cytoskeleton);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005768(endosome);GO:0005829(cytosol);GO:0005856(cytoskeleton);GO:0005885(Arp2/3 protein complex);GO:0005886(plasma membrane);GO:0005925(focal adhesion);GO:0010592(positive regulation of lamellipodium assembly);GO:0015629(actin cytoskeleton);GO:0030027(lamellipodium);GO:0030041(actin filament polymerization);GO:0030054(cell junction);GO:0030833(regulation of actin filament polymerization);GO:0030838(positive regulation of actin filament polymerization);GO:0031252(cell leading edge);GO:0034314(Arp2/3 complex-mediated actin nucleation);GO:0035861(site of double-strand break);GO:0036195(muscle cell projection membrane);GO:0038096(Fc-gamma receptor signaling pathway involved in phagocytosis);GO:0042995(cell projection);GO:0043005(neuron projection);GO:0045202(synapse);GO:0048013(ephrin receptor signaling pathway);GO:0051015(actin filament binding);GO:0061024(membrane organization);GO:0070062(extracellular exosome);GO:0070358(actin polymerization-dependent cell motility);GO:0098978(glutamatergic synapse);GO:1900026(positive regulation of substrate adhesion-dependent cell spreading)","04144(Endocytosis);04666(Fc gamma R-mediated phagocytosis);04810(Regulation of actin cytoskeleton);05100(Bacterial invasion of epithelial cells);05130(Pathogenic Escherichia coli infection);05131(Shigellosis);05132(Salmonella infection)","K05758","NA","actin related protein 2/3 complex subunit 2 [Source:HGNC Symbol;Acc:HGNC:705]",{"v":0.710893,"d":"0.71"},{"v":0.762095,"d":"0.76"},{"v":0.4832,"d":"0.48"},{"v":0.59712,"d":"0.60"},{"v":0.875474,"d":"0.88"},{"v":33.585575,"d":"33.59"},{"v":0.0557983504500763,"d":"0.06"},{"v":-4.16363371705128,"d":"-4.16"},{"v":0.00231103160312133,"d":"0.00"},{"v":0.128970473335481,"d":"0.13"},"down","yes"]
[138531,0,"chr3","+",39384432,39397012,"ENST00000643672",7,1612,"ENSG00000144659","SLC25A38","GO:0005739(mitochondrion);GO:0005743(mitochondrial inner membrane);GO:0006783(heme biosynthetic process);GO:0015187(glycine transmembrane transporter activity);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0022857(transmembrane transporter activity);GO:0030218(erythrocyte differentiation);GO:0055085(transmembrane transport);GO:1904983(glycine import into mitochondrion)","NA","K15118","NA","solute carrier family 25 member 38 [Source:HGNC Symbol;Acc:HGNC:26054]",{"v":1.284351,"d":"1.28"},{"v":1.284537,"d":"1.28"},0,{"v":0.012302,"d":"0.01"},0,0,{"v":208.818728662006,"d":"208.82"},{"v":7.70610730080168,"d":"7.71"},{"v":0.0023456494580748,"d":"0.00"},{"v":0.130617037409003,"d":"0.13"},"up","yes"]
[76381,0,"chr16","-",67438822,67481181,"ENST00000563064",8,1048,"ENSG00000159720","ATP6V0D1","GO:0005515(protein binding);GO:0005765(lysosomal membrane);GO:0005769(early endosome);GO:0005813(centrosome);GO:0006811(ion transport);GO:0006879(cellular iron ion homeostasis);GO:0007034(vacuolar transport);GO:0007035(vacuolar acidification);GO:0007420(brain development);GO:0008021(synaptic vesicle);GO:0008286(insulin receptor signaling pathway);GO:0008553(proton-exporting ATPase activity, phosphorylative mechanism);GO:0010008(endosome membrane);GO:0015078(proton transmembrane transporter activity);GO:0015991(ATP hydrolysis coupled proton transport);GO:0016020(membrane);GO:0016241(regulation of macroautophagy);GO:0016324(apical plasma membrane);GO:0016471(vacuolar proton-transporting V-type ATPase complex);GO:0030030(cell projection organization);GO:0030670(phagocytic vesicle membrane);GO:0032991(protein-containing complex);GO:0033179(proton-transporting V-type ATPase, V0 domain);GO:0033181(plasma membrane proton-transporting V-type ATPase complex);GO:0033572(transferrin transport);GO:0034220(ion transmembrane transport);GO:0036295(cellular response to increased oxygen levels);GO:0036498(IRE1-mediated unfolded protein response);GO:0043005(neuron projection);GO:0043679(axon terminus);GO:0044877(protein-containing complex binding);GO:0046961(proton-transporting ATPase activity, rotational mechanism);GO:0060271(cilium assembly);GO:0070062(extracellular exosome);GO:0090383(phagosome acidification);GO:1902600(proton transmembrane transport)","00190(Oxidative phosphorylation);04142(Lysosome);04145(Phagosome);04721(Synaptic vesicle cycle);04966(Collecting duct acid secretion);05110(Vibrio cholerae infection);05120(Epithelial cell signaling in Helicobacter pylori infection);05152(Tuberculosis);05165(Human papillomavirus infection);05203(Viral carcinogenesis);05323(Rheumatoid arthritis)","NA","NA","ATPase H+ transporting V0 subunit d1 [Source:HGNC Symbol;Acc:HGNC:13724]",{"v":2.75686,"d":"2.76"},{"v":4.966823,"d":"4.97"},{"v":3.158762,"d":"3.16"},{"v":0.5281,"d":"0.53"},{"v":0.297432,"d":"0.30"},{"v":0.136079,"d":"0.14"},{"v":11.3168890538898,"d":"11.32"},{"v":3.50040551919217,"d":"3.50"},{"v":0.00234772709683674,"d":"0.00"},{"v":0.130617037409003,"d":"0.13"},"up","yes"]
[200264,0,"chr9","+",133348922,133350383,"ENST00000485706",3,743,"ENSG00000148303","RPL7A","GO:0000184(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay);GO:0000470(maturation of LSU-rRNA);GO:0003723(RNA binding);GO:0003735(structural constituent of ribosome);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005730(nucleolus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005840(ribosome);GO:0005925(focal adhesion);GO:0006412(translation);GO:0006413(translational initiation);GO:0006614(SRP-dependent cotranslational protein targeting to membrane);GO:0016020(membrane);GO:0019083(viral transcription);GO:0022625(cytosolic large ribosomal subunit);GO:0042254(ribosome biogenesis);GO:0042788(polysomal ribosome);GO:0045296(cadherin binding);GO:1990904(ribonucleoprotein complex)","03010(Ribosome)","K02936","NA","ribosomal protein L7a [Source:HGNC Symbol;Acc:HGNC:10364]",{"v":3.271722,"d":"3.27"},{"v":2.564785,"d":"2.56"},{"v":4.322439,"d":"4.32"},{"v":9.20759,"d":"9.21"},{"v":34.046799,"d":"34.05"},{"v":30.699078,"d":"30.70"},{"v":0.137369435296387,"d":"0.14"},{"v":-2.86386705471676,"d":"-2.86"},{"v":0.00237068244668396,"d":"0.00"},{"v":0.131692497382306,"d":"0.13"},"down","yes"]
[14244,0,"chr1","-",175944831,176206691,"ENST00000367667",18,2034,"ENSG00000143207","COP1","GO:0000139(Golgi membrane);GO:0004842(ubiquitin-protein transferase activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0010212(response to ionizing radiation);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016567(protein ubiquitination);GO:0016607(nuclear speck);GO:0016740(transferase activity);GO:0031464(Cul4A-RING E3 ubiquitin ligase complex);GO:0032436(positive regulation of proteasomal ubiquitin-dependent protein catabolic process);GO:0043161(proteasome-mediated ubiquitin-dependent protein catabolic process);GO:0043687(post-translational protein modification);GO:0046872(metal ion binding);GO:0061630(ubiquitin protein ligase activity)","04115(p53 signaling pathway);04120(Ubiquitin mediated proteolysis)","K10143","EC:2.3.2.27","COP1, E3 ubiquitin ligase [Source:HGNC Symbol;Acc:HGNC:17440]",{"v":0.454221,"d":"0.45"},{"v":1.707245,"d":"1.71"},{"v":0.735285,"d":"0.74"},{"v":0.06945,"d":"0.07"},0,0,{"v":41.7098776097912,"d":"41.71"},{"v":5.38231717378901,"d":"5.38"},{"v":0.00238634768337467,"d":"0.00"},{"v":0.132360322651911,"d":"0.13"},"up","yes"]
[23886,0,"chr10","+",102152176,102163866,"ENST00000605788",13,3932,"ENSG00000166197","NOLC1","GO:0000166(nucleotide binding);GO:0000278(mitotic cell cycle);GO:0001042(RNA polymerase I core binding);GO:0001650(fibrillar center);GO:0003677(DNA binding);GO:0003700(DNA-binding transcription factor activity);GO:0003723(RNA binding);GO:0005515(protein binding);GO:0005524(ATP binding);GO:0005525(GTP binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005730(nucleolus);GO:0005737(cytoplasm);GO:0006364(rRNA processing);GO:0006417(regulation of translation);GO:0006970(response to osmotic stress);GO:0007000(nucleolus organization);GO:0008134(transcription factor binding);GO:0008139(nuclear localization sequence binding);GO:0008284(positive regulation of cell population proliferation);GO:0014029(neural crest formation);GO:0014032(neural crest cell development);GO:0015030(Cajal body);GO:0019904(protein domain specific binding);GO:0031428(box C/D snoRNP complex);GO:0031429(box H/ACA snoRNP complex);GO:0033979(box H/ACA snoRNA metabolic process);GO:0034512(box C/D snoRNA binding);GO:0034513(box H/ACA snoRNA binding);GO:0042306(regulation of protein import into nucleus);GO:0045893(positive regulation of transcription, DNA-templated);GO:0046982(protein heterodimerization activity);GO:0062064(box C/D snoRNP complex binding);GO:0062065(box H/ACA snoRNP complex binding)","NA","NA","NA","nucleolar and coiled-body phosphoprotein 1 [Source:HGNC Symbol;Acc:HGNC:15608]",{"v":0.173167,"d":"0.17"},{"v":0.193149,"d":"0.19"},{"v":0.11118,"d":"0.11"},{"v":0.118582,"d":"0.12"},{"v":2.157969,"d":"2.16"},{"v":5.088194,"d":"5.09"},{"v":0.0648353744766452,"d":"0.06"},{"v":-3.94707502084466,"d":"-3.95"},{"v":0.00239837772565984,"d":"0.00"},{"v":0.132824790812838,"d":"0.13"},"down","yes"]
[120049,0,"chr2","+",186486263,186501375,"ENST00000437396",5,556,"ENSG00000065548","ZC3H15","GO:0002181(cytoplasmic translation);GO:0003723(RNA binding);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005730(nucleolus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0019221(cytokine-mediated signaling pathway);GO:0043547(positive regulation of GTPase activity);GO:0045296(cadherin binding);GO:0046872(metal ion binding)","NA","NA","NA","zinc finger CCCH-type containing 15 [Source:HGNC Symbol;Acc:HGNC:29528]",{"v":0.043495,"d":"0.04"},{"v":0.042834,"d":"0.04"},{"v":0.098846,"d":"0.10"},{"v":3.170151,"d":"3.17"},{"v":0.128654,"d":"0.13"},{"v":3.549498,"d":"3.55"},{"v":0.02703954541731,"d":"0.03"},{"v":-5.20878529221178,"d":"-5.21"},{"v":0.00241584040665583,"d":"0.00"},{"v":0.133588252623754,"d":"0.13"},"down","yes"]
[18697,0,"chr10","-",3775996,3785209,"ENST00000497571",4,4590,"ENSG00000067082","KLF6","GO:0000978(RNA polymerase II proximal promoter sequence-specific DNA binding);GO:0000981(DNA-binding transcription factor activity, RNA polymerase II-specific);GO:0001228(DNA-binding transcription activator activity, RNA polymerase II-specific);GO:0001650(fibrillar center);GO:0003676(nucleic acid binding);GO:0003677(DNA binding);GO:0003690(double-stranded DNA binding);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005730(nucleolus);GO:0005829(cytosol);GO:0006357(regulation of transcription by RNA polymerase II);GO:0019221(cytokine-mediated signaling pathway);GO:0030183(B cell differentiation);GO:0043231(intracellular membrane-bounded organelle);GO:0045893(positive regulation of transcription, DNA-templated);GO:0045944(positive regulation of transcription by RNA polymerase II);GO:0046872(metal ion binding)","NA","NA","NA","Kruppel like factor 6 [Source:HGNC Symbol;Acc:HGNC:2235]",{"v":15.122311,"d":"15.12"},{"v":43.487579,"d":"43.49"},{"v":45.056381,"d":"45.06"},{"v":7.28987,"d":"7.29"},{"v":7.115769,"d":"7.12"},{"v":8.842365,"d":"8.84"},{"v":4.45914715947227,"d":"4.46"},{"v":2.15676781183787,"d":"2.16"},{"v":0.00242554319567229,"d":"0.00"},{"v":0.133920948782332,"d":"0.13"},"up","yes"]
[2299,0,"chr1","-",19339359,19484664,"ENST00000433834",9,1462,"ENSG00000077549","CAPZB","GO:0000902(cell morphogenesis);GO:0003779(actin binding);GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005856(cytoskeleton);GO:0005903(brush border);GO:0006888(endoplasmic reticulum to Golgi vesicle-mediated transport);GO:0007010(cytoskeleton organization);GO:0007596(blood coagulation);GO:0008290(F-actin capping protein complex);GO:0010591(regulation of lamellipodium assembly);GO:0014069(postsynaptic density);GO:0015629(actin cytoskeleton);GO:0016020(membrane);GO:0019886(antigen processing and presentation of exogenous peptide antigen via MHC class II);GO:0022604(regulation of cell morphogenesis);GO:0030017(sarcomere);GO:0030027(lamellipodium);GO:0030030(cell projection organization);GO:0030032(lamellipodium assembly);GO:0030036(actin cytoskeleton organization);GO:0030863(cortical cytoskeleton);GO:0032279(asymmetric synapse);GO:0045296(cadherin binding);GO:0051015(actin filament binding);GO:0051016(barbed-end actin filament capping);GO:0051490(negative regulation of filopodium assembly);GO:0051693(actin filament capping);GO:0070062(extracellular exosome);GO:0071203(WASH complex);GO:0098685(Schaffer collateral - CA1 synapse);GO:0098686(hippocampal mossy fiber to CA3 synapse)","04144(Endocytosis)","NA","NA","capping actin protein of muscle Z-line subunit beta [Source:HGNC Symbol;Acc:HGNC:1491]",{"v":23.319122,"d":"23.32"},{"v":19.676182,"d":"19.68"},{"v":104.699181,"d":"104.70"},{"v":7.771417,"d":"7.77"},{"v":10.247216,"d":"10.25"},{"v":6.764421,"d":"6.76"},{"v":5.95949494360138,"d":"5.96"},{"v":2.57519007007731,"d":"2.58"},{"v":0.00244738423492881,"d":"0.00"},{"v":0.134737832527355,"d":"0.13"},"up","yes"]
[20076,0,"chr10","-",29458059,29634972,"ENST00000355867",38,7586,"ENSG00000197321","SVIL","GO:0002102(podosome);GO:0003779(actin binding);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005856(cytoskeleton);GO:0005886(plasma membrane);GO:0005925(focal adhesion);GO:0007010(cytoskeleton organization);GO:0007519(skeletal muscle tissue development);GO:0015629(actin cytoskeleton);GO:0016020(membrane);GO:0030054(cell junction);GO:0030496(midbody);GO:0032154(cleavage furrow);GO:0032467(positive regulation of cytokinesis);GO:0036449(microtubule minus-end);GO:0042995(cell projection);GO:0043034(costamere);GO:0051015(actin filament binding);GO:0071437(invadopodium)","NA","K10369","NA","supervillin [Source:HGNC Symbol;Acc:HGNC:11480]",{"v":7.244468,"d":"7.24"},{"v":0.105312,"d":"0.11"},{"v":0.558171,"d":"0.56"},{"v":0.133358,"d":"0.13"},{"v":0.176639,"d":"0.18"},{"v":0.164929,"d":"0.16"},{"v":16.650911931543,"d":"16.65"},{"v":4.05752928738431,"d":"4.06"},{"v":0.00244775583451841,"d":"0.00"},{"v":0.134737832527355,"d":"0.13"},"up","yes"]
[60522,0,"chr14","+",102032435,102050671,"ENST00000643437",26,4773,"ENSG00000197102","DYNC1H1","GO:0000086(G2/M transition of mitotic cell cycle);GO:0000166(nucleotide binding);GO:0003723(RNA binding);GO:0003774(motor activity);GO:0003777(microtubule motor activity);GO:0005515(protein binding);GO:0005524(ATP binding);GO:0005576(extracellular region);GO:0005737(cytoplasm);GO:0005813(centrosome);GO:0005829(cytosol);GO:0005856(cytoskeleton);GO:0005868(cytoplasmic dynein complex);GO:0005874(microtubule);GO:0006888(endoplasmic reticulum to Golgi vesicle-mediated transport);GO:0007018(microtubule-based movement);GO:0007049(cell cycle);GO:0007052(mitotic spindle organization);GO:0008569(ATP-dependent microtubule motor activity, minus-end-directed);GO:0010389(regulation of G2/M transition of mitotic cell cycle);GO:0016020(membrane);GO:0019886(antigen processing and presentation of exogenous peptide antigen via MHC class II);GO:0030175(filopodium);GO:0030286(dynein complex);GO:0031122(cytoplasmic microtubule organization);GO:0032388(positive regulation of intracellular transport);GO:0033962(cytoplasmic mRNA processing body assembly);GO:0034063(stress granule assembly);GO:0035578(azurophil granule lumen);GO:0043312(neutrophil degranulation);GO:0045503(dynein light chain binding);GO:0045505(dynein intermediate chain binding);GO:0051293(establishment of spindle localization);GO:0051301(cell division);GO:0051959(dynein light intermediate chain binding);GO:0060236(regulation of mitotic spindle organization);GO:0070062(extracellular exosome);GO:0072382(minus-end-directed vesicle transport along microtubule);GO:0090235(regulation of metaphase plate congression);GO:0097711(ciliary basal body-plasma membrane docking);GO:0120162(positive regulation of cold-induced thermogenesis);GO:1905832(positive regulation of spindle assembly)","04145(Phagosome);04962(Vasopressin-regulated water reabsorption);05132(Salmonella infection)","K10413","NA","dynein cytoplasmic 1 heavy chain 1 [Source:HGNC Symbol;Acc:HGNC:2961]",{"v":3.404139,"d":"3.40"},{"v":0.602878,"d":"0.60"},{"v":0.298157,"d":"0.30"},{"v":14.137526,"d":"14.14"},{"v":4.501849,"d":"4.50"},{"v":15.625183,"d":"15.63"},{"v":0.125645105359304,"d":"0.13"},{"v":-2.99257362431663,"d":"-2.99"},{"v":0.00246588031537053,"d":"0.00"},{"v":0.135530154095932,"d":"0.14"},"down","yes"]
[42720,0,"chr12","+",50057745,50083611,"ENST00000550558",13,3819,"ENSG00000110881","ASIC1","GO:0001662(behavioral fear response);GO:0001975(response to amphetamine);GO:0005216(ion channel activity);GO:0005261(cation channel activity);GO:0005272(sodium channel activity);GO:0005515(protein binding);GO:0005794(Golgi apparatus);GO:0005886(plasma membrane);GO:0005887(integral component of plasma membrane);GO:0006811(ion transport);GO:0006812(cation transport);GO:0006814(sodium ion transport);GO:0006816(calcium ion transport);GO:0007165(signal transduction);GO:0007613(memory);GO:0008306(associative learning);GO:0009268(response to pH);GO:0009986(cell surface);GO:0010447(response to acidic pH);GO:0015280(ligand-gated sodium channel activity);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0022839(ion gated channel activity);GO:0034220(ion transmembrane transport);GO:0035725(sodium ion transmembrane transport);GO:0042391(regulation of membrane potential);GO:0044736(acid-sensing ion channel activity);GO:0045202(synapse);GO:0046929(negative regulation of neurotransmitter secretion);GO:0050915(sensory perception of sour taste);GO:0070207(protein homotrimerization);GO:0070588(calcium ion transmembrane transport);GO:0071467(cellular response to pH)","04750(Inflammatory mediator regulation of TRP channels)","NA","NA","acid sensing ion channel subunit 1 [Source:HGNC Symbol;Acc:HGNC:100]",{"v":0.015241,"d":"0.02"},{"v":2.224025,"d":"2.22"},{"v":1.599031,"d":"1.60"},0,0,{"v":0.050689,"d":"0.05"},{"v":75.7224841681627,"d":"75.72"},{"v":6.24264983607031,"d":"6.24"},{"v":0.00247407412843836,"d":"0.00"},{"v":0.135775095296322,"d":"0.14"},"up","yes"]
[69271,0,"chr16","+",590066,629268,"ENST00000248139",6,2718,"ENSG00000197562","RAB40C","GO:0000139(Golgi membrane);GO:0000166(nucleotide binding);GO:0003924(GTPase activity);GO:0005525(GTP binding);GO:0005886(plasma membrane);GO:0006886(intracellular protein transport);GO:0016020(membrane);GO:0016567(protein ubiquitination);GO:0019003(GDP binding);GO:0032482(Rab protein signal transduction);GO:0035556(intracellular signal transduction);GO:0048471(perinuclear region of cytoplasm)","NA","K07928","NA","RAB40C, member RAS oncogene family [Source:HGNC Symbol;Acc:HGNC:18285]",{"v":0.344708,"d":"0.34"},{"v":0.264702,"d":"0.26"},{"v":0.448851,"d":"0.45"},{"v":5.069561,"d":"5.07"},{"v":0.628925,"d":"0.63"},{"v":5.547194,"d":"5.55"},{"v":0.0941037802960781,"d":"0.09"},{"v":-3.40960351033994,"d":"-3.41"},{"v":0.00252941167366801,"d":"0.00"},{"v":0.138602603475654,"d":"0.14"},"down","yes"]
[138792,0,"chr3","-",42548183,42581962,"ENST00000449617",8,1446,"ENSG00000093183","SEC22C","GO:0005515(protein binding);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0006888(endoplasmic reticulum to Golgi vesicle-mediated transport);GO:0015031(protein transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016192(vesicle-mediated transport)","NA","K08520","NA","SEC22 homolog C, vesicle trafficking protein [Source:HGNC Symbol;Acc:HGNC:16828]",{"v":0.176415,"d":"0.18"},{"v":0.017984,"d":"0.02"},0,{"v":1.401204,"d":"1.40"},{"v":1.719638,"d":"1.72"},{"v":1.16905,"d":"1.17"},{"v":0.0453155930265843,"d":"0.05"},{"v":-4.46384862490575,"d":"-4.46"},{"v":0.00255478923712729,"d":"0.00"},{"v":0.139782368953064,"d":"0.14"},"down","yes"]
[71796,0,"chr16","+",14975129,15036604,"ENST00000627450",22,2683,"ENSG00000179889","PDXDC1","GO:0001667(ameboidal-type cell migration);GO:0003824(catalytic activity);GO:0005783(endoplasmic reticulum);GO:0005794(Golgi apparatus);GO:0006665(sphingolipid metabolic process);GO:0008117(sphinganine-1-phosphate aldolase activity);GO:0016829(lyase activity);GO:0016831(carboxy-lyase activity);GO:0019752(carboxylic acid metabolic process);GO:0030149(sphingolipid catabolic process);GO:0030170(pyridoxal phosphate binding);GO:0043231(intracellular membrane-bounded organelle);GO:0045296(cadherin binding)","NA","NA","NA","pyridoxal dependent decarboxylase domain containing 1 [Source:HGNC Symbol;Acc:HGNC:28995]",{"v":0.16027,"d":"0.16"},0,{"v":0.206603,"d":"0.21"},{"v":18.340536,"d":"18.34"},{"v":12.624356,"d":"12.62"},0,{"v":0.0118480309894186,"d":"0.01"},{"v":-6.39920887055271,"d":"-6.40"},{"v":0.00256121075628315,"d":"0.00"},{"v":0.139922987632732,"d":"0.14"},"down","yes"]
[63636,0,"chr15","+",43800423,43802291,"ENST00000442995",4,1051,"ENSG00000242028","HYPK","GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0015630(microtubule cytoskeleton);GO:0032991(protein-containing complex);GO:0043066(negative regulation of apoptotic process);GO:0047485(protein N-terminus binding);GO:0050821(protein stabilization)","NA","NA","NA","huntingtin interacting protein K [Source:HGNC Symbol;Acc:HGNC:18418]",{"v":0.03198,"d":"0.03"},{"v":0.001062,"d":"0.00"},{"v":0.046425,"d":"0.05"},{"v":1.492214,"d":"1.49"},{"v":0.059927,"d":"0.06"},{"v":2.174599,"d":"2.17"},{"v":0.021323462329006,"d":"0.02"},{"v":-5.55141447966382,"d":"-5.55"},{"v":0.00259912726684599,"d":"0.00"},{"v":0.141523041021136,"d":"0.14"},"down","yes"]
[168930,0,"chr6","-",31355122,31355802,"ENST00000463574",2,588,"ENSG00000234745","HLA-B","GO:0000139(Golgi membrane);GO:0001916(positive regulation of T cell mediated cytotoxicity);GO:0002376(immune system process);GO:0002474(antigen processing and presentation of peptide antigen via MHC class I);GO:0002476(antigen processing and presentation of endogenous peptide antigen via MHC class Ib);GO:0002479(antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent);GO:0002480(antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent);GO:0002486(antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent);GO:0002667(regulation of T cell anergy);GO:0005102(signaling receptor binding);GO:0005515(protein binding);GO:0005615(extracellular space);GO:0005783(endoplasmic reticulum);GO:0005794(Golgi apparatus);GO:0005886(plasma membrane);GO:0005887(integral component of plasma membrane);GO:0006955(immune response);GO:0009897(external side of plasma membrane);GO:0009986(cell surface);GO:0012507(ER to Golgi transport vesicle membrane);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016032(viral process);GO:0019882(antigen processing and presentation);GO:0030667(secretory granule membrane);GO:0030670(phagocytic vesicle membrane);GO:0031901(early endosome membrane);GO:0032655(regulation of interleukin-12 production);GO:0032675(regulation of interleukin-6 production);GO:0042270(protection from natural killer cell mediated cytotoxicity);GO:0042605(peptide antigen binding);GO:0042612(MHC class I protein complex);GO:0043312(neutrophil degranulation);GO:0050776(regulation of immune response);GO:0055038(recycling endosome membrane);GO:0060333(interferon-gamma-mediated signaling pathway);GO:0060337(type I interferon signaling pathway);GO:0070062(extracellular exosome);GO:0071556(integral component of lumenal side of endoplasmic reticulum membrane);GO:2001198(regulation of dendritic cell differentiation)","04144(Endocytosis);04145(Phagosome);04218(Cellular senescence);04514(Cell adhesion molecules (CAMs));04612(Antigen processing and presentation);04650(Natural killer cell mediated cytotoxicity);04940(Type I diabetes mellitus);05163(Human cytomegalovirus infection);05165(Human papillomavirus infection);05166(Human T-cell leukemia virus 1 infection);05167(Kaposi sarcoma-associated herpesvirus infection);05168(Herpes simplex virus 1 infection);05169(Epstein-Barr virus infection);05170(Human immunodeficiency virus 1 infection);05203(Viral carcinogenesis);05320(Autoimmune thyroid disease);05330(Allograft rejection);05332(Graft-versus-host disease);05416(Viral myocarditis)","K06751","NA","major histocompatibility complex, class I, B [Source:HGNC Symbol;Acc:HGNC:4932]",{"v":13.990543,"d":"13.99"},{"v":1.100079,"d":"1.10"},{"v":6.980189,"d":"6.98"},{"v":0.520492,"d":"0.52"},{"v":0.632509,"d":"0.63"},{"v":0.500171,"d":"0.50"},{"v":13.3505836053357,"d":"13.35"},{"v":3.73883090392533,"d":"3.74"},{"v":0.00259978712454823,"d":"0.00"},{"v":0.141523041021136,"d":"0.14"},"up","yes"]
[1386,0,"chr1","-",9850109,9910336,"ENST00000400904",5,1206,"ENSG00000178585","CTNNBIP1","GO:0000122(negative regulation of transcription by RNA polymerase II);GO:0001658(branching involved in ureteric bud morphogenesis);GO:0002528(regulation of vascular permeability involved in acute inflammatory response);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0008013(beta-catenin binding);GO:0009952(anterior/posterior pattern specification);GO:0016055(Wnt signaling pathway);GO:0030178(negative regulation of Wnt signaling pathway);GO:0030877(beta-catenin destruction complex);GO:0031333(negative regulation of protein complex assembly);GO:0032091(negative regulation of protein binding);GO:0043392(negative regulation of DNA binding);GO:0043433(negative regulation of DNA-binding transcription factor activity);GO:0045657(positive regulation of monocyte differentiation);GO:0045669(positive regulation of osteoblast differentiation);GO:0048662(negative regulation of smooth muscle cell proliferation);GO:0060633(negative regulation of transcription initiation from RNA polymerase II promoter);GO:0070016(armadillo repeat domain binding);GO:0072201(negative regulation of mesenchymal cell proliferation)","04310(Wnt signaling pathway)","K04493","NA","catenin beta interacting protein 1 [Source:HGNC Symbol;Acc:HGNC:16913]",{"v":2.236627,"d":"2.24"},{"v":2.277683,"d":"2.28"},{"v":2.086774,"d":"2.09"},{"v":0.213049,"d":"0.21"},{"v":0.253788,"d":"0.25"},{"v":0.237642,"d":"0.24"},{"v":9.3701643342101,"d":"9.37"},{"v":3.22807435013323,"d":"3.23"},{"v":0.00260218528494684,"d":"0.00"},{"v":0.141523041021136,"d":"0.14"},"up","yes"]
[106012,0,"chr19","-",48615336,48619176,"ENST00000549370",7,628,"ENSG00000063177","RPL18","GO:0000184(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay);GO:0002181(cytoplasmic translation);GO:0003723(RNA binding);GO:0003735(structural constituent of ribosome);GO:0005622(intracellular);GO:0005634(nucleus);GO:0005730(nucleolus);GO:0005737(cytoplasm);GO:0005783(endoplasmic reticulum);GO:0005791(rough endoplasmic reticulum);GO:0005829(cytosol);GO:0005840(ribosome);GO:0005925(focal adhesion);GO:0006412(translation);GO:0006413(translational initiation);GO:0006614(SRP-dependent cotranslational protein targeting to membrane);GO:0016020(membrane);GO:0019083(viral transcription);GO:0022625(cytosolic large ribosomal subunit);GO:0042788(polysomal ribosome)","03010(Ribosome)","K02883","NA","ribosomal protein L18 [Source:HGNC Symbol;Acc:HGNC:10310]",{"v":2.289737,"d":"2.29"},{"v":9.500839,"d":"9.50"},{"v":10.078532,"d":"10.08"},{"v":87.357048,"d":"87.36"},{"v":58.627647,"d":"58.63"},{"v":12.745606,"d":"12.75"},{"v":0.137775256912037,"d":"0.14"},{"v":-2.85961127749465,"d":"-2.86"},{"v":0.00261960425593453,"d":"0.00"},{"v":0.142139531444337,"d":"0.14"},"down","yes"]
[114135,0,"chr2","+",74530046,74533192,"ENST00000437202",7,1479,"ENSG00000115317","HTRA2","GO:0000785(chromatin);GO:0004252(serine-type endopeptidase activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005739(mitochondrion);GO:0005758(mitochondrial intermembrane space);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005829(cytosol);GO:0005856(cytoskeleton);GO:0006508(proteolysis);GO:0006672(ceramide metabolic process);GO:0006915(apoptotic process);GO:0007005(mitochondrion organization);GO:0007568(aging);GO:0007628(adult walking behavior);GO:0008233(peptidase activity);GO:0008236(serine-type peptidase activity);GO:0008344(adult locomotory behavior);GO:0008630(intrinsic apoptotic signaling pathway in response to DNA damage);GO:0009635(response to herbicide);GO:0009898(cytoplasmic side of plasma membrane);GO:0010822(positive regulation of mitochondrion organization);GO:0010942(positive regulation of cell death);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016540(protein autoprocessing);GO:0016787(hydrolase activity);GO:0019742(pentacyclic triterpenoid metabolic process);GO:0030900(forebrain development);GO:0031966(mitochondrial membrane);GO:0034599(cellular response to oxidative stress);GO:0034605(cellular response to heat);GO:0035458(cellular response to interferon-beta);GO:0035631(CD40 receptor complex);GO:0040014(regulation of multicellular organism growth);GO:0042802(identical protein binding);GO:0043065(positive regulation of apoptotic process);GO:0043280(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process);GO:0044257(cellular protein catabolic process);GO:0045786(negative regulation of cell cycle);GO:0048666(neuron development);GO:0051082(unfolded protein binding);GO:0060548(negative regulation of cell death);GO:0070207(protein homotrimerization);GO:0071300(cellular response to retinoic acid);GO:0071363(cellular response to growth factor stimulus);GO:0097193(intrinsic apoptotic signaling pathway);GO:0097194(execution phase of apoptosis);GO:1901215(negative regulation of neuron death);GO:1902176(negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway);GO:1903146(regulation of autophagy of mitochondrion);GO:1903955(positive regulation of protein targeting to mitochondrion);GO:1904924(negative regulation of mitophagy in response to mitochondrial depolarization);GO:1905370(serine-type endopeptidase complex);GO:2001241(positive regulation of extrinsic apoptotic signaling pathway in absence of ligand);GO:2001269(positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway)","04210(Apoptosis);04215(Apoptosis - multiple species);05012(Parkinson disease)","K08669","EC:3.4.21.108","HtrA serine peptidase 2 [Source:HGNC Symbol;Acc:HGNC:14348]",{"v":0.563469,"d":"0.56"},{"v":0.124922,"d":"0.12"},{"v":1.346998,"d":"1.35"},{"v":0.026869,"d":"0.03"},{"v":0.023671,"d":"0.02"},{"v":0.015289,"d":"0.02"},{"v":30.9193364626532,"d":"30.92"},{"v":4.95043745385545,"d":"4.95"},{"v":0.0026213456115526,"d":"0.00"},{"v":0.142139531444337,"d":"0.14"},"up","yes"]
[135612,0,"chr22","+",46150596,46243756,"ENST00000262735",8,9965,"ENSG00000186951","PPARA","GO:0000122(negative regulation of transcription by RNA polymerase II);GO:0000976(transcription regulatory region sequence-specific DNA binding);GO:0000977(RNA polymerase II regulatory region sequence-specific DNA binding);GO:0000978(RNA polymerase II proximal promoter sequence-specific DNA binding);GO:0000981(DNA-binding transcription factor activity, RNA polymerase II-specific);GO:0001103(RNA polymerase II repressing transcription factor binding);GO:0001223(transcription coactivator binding);GO:0001227(DNA-binding transcription repressor activity, RNA polymerase II-specific);GO:0001228(DNA-binding transcription activator activity, RNA polymerase II-specific);GO:0001666(response to hypoxia);GO:0003677(DNA binding);GO:0003700(DNA-binding transcription factor activity);GO:0003707(steroid hormone receptor activity);GO:0004879(nuclear receptor activity);GO:0005504(fatty acid binding);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0006355(regulation of transcription, DNA-templated);GO:0006367(transcription initiation from RNA polymerase II promoter);GO:0006629(lipid metabolic process);GO:0006631(fatty acid metabolic process);GO:0007275(multicellular organism development);GO:0007507(heart development);GO:0008134(transcription factor binding);GO:0008144(drug binding);GO:0008270(zinc ion binding);GO:0008289(lipid binding);GO:0008544(epidermis development);GO:0009755(hormone-mediated signaling pathway);GO:0010468(regulation of gene expression);GO:0010745(negative regulation of macrophage derived foam cell differentiation);GO:0010871(negative regulation of receptor biosynthetic process);GO:0010887(negative regulation of cholesterol storage);GO:0010891(negative regulation of sequestering of triglyceride);GO:0015908(fatty acid transport);GO:0019216(regulation of lipid metabolic process);GO:0019217(regulation of fatty acid metabolic process);GO:0019902(phosphatase binding);GO:0019904(protein domain specific binding);GO:0030154(cell differentiation);GO:0030374(nuclear receptor transcription coactivator activity);GO:0030522(intracellular receptor signaling pathway);GO:0031624(ubiquitin conjugating enzyme binding);GO:0032000(positive regulation of fatty acid beta-oxidation);GO:0032091(negative regulation of protein binding);GO:0032099(negative regulation of appetite);GO:0032868(response to insulin);GO:0032922(circadian regulation of gene expression);GO:0033993(response to lipid);GO:0035095(behavioral response to nicotine);GO:0038023(signaling receptor activity);GO:0042060(wound healing);GO:0042157(lipoprotein metabolic process);GO:0042752(regulation of circadian rhythm);GO:0043401(steroid hormone mediated signaling pathway);GO:0043565(sequence-specific DNA binding);GO:0044877(protein-containing complex binding);GO:0045722(positive regulation of gluconeogenesis);GO:0045776(negative regulation of blood pressure);GO:0045820(negative regulation of glycolytic process);GO:0045892(negative regulation of transcription, DNA-templated);GO:0045893(positive regulation of transcription, DNA-templated);GO:0045944(positive regulation of transcription by RNA polymerase II);GO:0046321(positive regulation of fatty acid oxidation);GO:0046872(metal ion binding);GO:0048511(rhythmic process);GO:0050728(negative regulation of inflammatory response);GO:0051525(NFAT protein binding);GO:0061052(negative regulation of cell growth involved in cardiac muscle cell development);GO:0070166(enamel mineralization);GO:0072363(regulation of glycolytic process by positive regulation of transcription from RNA polymerase II promoter);GO:0072366(regulation of cellular ketone metabolic process by positive regulation of transcription from RNA polymerase II promoter);GO:0072369(regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter);GO:0090575(RNA polymerase II transcription factor complex);GO:0097371(MDM2/MDM4 family protein binding);GO:1901215(negative regulation of neuron death);GO:1902894(negative regulation of pri-miRNA transcription by RNA polymerase II);GO:1903038(negative regulation of leukocyte cell-cell adhesion)","03320(PPAR signaling pathway);04024(cAMP signaling pathway);04920(Adipocytokine signaling pathway);04922(Glucagon signaling pathway);04931(Insulin resistance);04932(Non-alcoholic fatty liver disease (NAFLD));05160(Hepatitis C)","NA","NA","peroxisome proliferator activated receptor alpha [Source:HGNC Symbol;Acc:HGNC:9232]",{"v":0.141129,"d":"0.14"},{"v":0.055245,"d":"0.06"},{"v":0.002062,"d":"0.00"},{"v":3.98453,"d":"3.98"},{"v":0.00225,"d":"0.00"},{"v":3.68224,"d":"3.68"},{"v":0.0258750140174364,"d":"0.03"},{"v":-5.27229654560216,"d":"-5.27"},{"v":0.00262900633096212,"d":"0.00"},{"v":0.142342473925266,"d":"0.14"},"down","yes"]
[35656,0,"chr11","+",102110461,102233423,"ENST00000615667",9,5398,"ENSG00000137693","YAP1","GO:0000902(cell morphogenesis);GO:0000978(RNA polymerase II proximal promoter sequence-specific DNA binding);GO:0001570(vasculogenesis);GO:0001894(tissue homeostasis);GO:0003015(heart process);GO:0003143(embryonic heart tube morphogenesis);GO:0003682(chromatin binding);GO:0003713(transcription coactivator activity);GO:0003714(transcription corepressor activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005667(transcription factor complex);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0006367(transcription initiation from RNA polymerase II promoter);GO:0006974(cellular response to DNA damage stimulus);GO:0008022(protein C-terminus binding);GO:0008134(transcription factor binding);GO:0008283(cell population proliferation);GO:0008284(positive regulation of cell population proliferation);GO:0010468(regulation of gene expression);GO:0010837(regulation of keratinocyte proliferation);GO:0016020(membrane);GO:0030216(keratinocyte differentiation);GO:0030857(negative regulation of epithelial cell differentiation);GO:0030903(notochord development);GO:0032570(response to progesterone);GO:0033148(positive regulation of intracellular estrogen receptor signaling pathway);GO:0033613(activating transcription factor binding);GO:0035019(somatic stem cell population maintenance);GO:0035329(hippo signaling);GO:0042127(regulation of cell population proliferation);GO:0044212(transcription regulatory region DNA binding);GO:0045893(positive regulation of transcription, DNA-templated);GO:0045944(positive regulation of transcription by RNA polymerase II);GO:0046622(positive regulation of organ growth);GO:0046982(protein heterodimerization activity);GO:0048339(paraxial mesoderm development);GO:0048368(lateral mesoderm development);GO:0050767(regulation of neurogenesis);GO:0050847(progesterone receptor signaling pathway);GO:0060045(positive regulation of cardiac muscle cell proliferation);GO:0060242(contact inhibition);GO:0060449(bud elongation involved in lung branching);GO:0060487(lung epithelial cell differentiation);GO:0060828(regulation of canonical Wnt signaling pathway);GO:0061026(cardiac muscle tissue regeneration);GO:0065003(protein-containing complex assembly);GO:0070064(proline-rich region binding);GO:0071148(TEAD-1-YAP complex);GO:0071149(TEAD-2-YAP complex);GO:0071300(cellular response to retinoic acid);GO:0071480(cellular response to gamma radiation);GO:0072091(regulation of stem cell proliferation);GO:0072307(regulation of metanephric nephron tubule epithelial cell differentiation);GO:0090263(positive regulation of canonical Wnt signaling pathway);GO:1902036(regulation of hematopoietic stem cell differentiation);GO:1902459(positive regulation of stem cell population maintenance);GO:1903507(negative regulation of nucleic acid-templated transcription);GO:2000737(negative regulation of stem cell differentiation);GO:2001237(negative regulation of extrinsic apoptotic signaling pathway)","04390(Hippo signaling pathway);04392(Hippo signaling pathway - multiple species)","K16687","NA","Yes associated protein 1 [Source:HGNC Symbol;Acc:HGNC:16262]",{"v":0.168541,"d":"0.17"},{"v":0.221583,"d":"0.22"},{"v":0.303728,"d":"0.30"},{"v":1.641551,"d":"1.64"},{"v":2.524132,"d":"2.52"},{"v":1.421902,"d":"1.42"},{"v":0.124177439806285,"d":"0.12"},{"v":-3.00952500213397,"d":"-3.01"},{"v":0.00263491185869448,"d":"0.00"},{"v":0.14244992236067,"d":"0.14"},"down","yes"]
[84241,0,"chr17","+",34980546,35003172,"ENST00000262327",20,3055,"ENSG00000005156","LIG3","GO:0000166(nucleotide binding);GO:0000724(double-strand break repair via homologous recombination);GO:0003677(DNA binding);GO:0003909(DNA ligase activity);GO:0003910(DNA ligase (ATP) activity);GO:0005515(protein binding);GO:0005524(ATP binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0005739(mitochondrion);GO:0006260(DNA replication);GO:0006266(DNA ligation);GO:0006273(lagging strand elongation);GO:0006281(DNA repair);GO:0006283(transcription-coupled nucleotide-excision repair);GO:0006288(base-excision repair, DNA ligation);GO:0006297(nucleotide-excision repair, DNA gap filling);GO:0006302(double-strand break repair);GO:0006310(DNA recombination);GO:0006974(cellular response to DNA damage stimulus);GO:0007049(cell cycle);GO:0008270(zinc ion binding);GO:0016874(ligase activity);GO:0043504(mitochondrial DNA repair);GO:0046872(metal ion binding);GO:0051103(DNA ligation involved in DNA repair);GO:0051301(cell division);GO:0071897(DNA biosynthetic process);GO:0090298(negative regulation of mitochondrial DNA replication);GO:0097681(double-strand break repair via alternative nonhomologous end joining)","03410(Base excision repair)","K10776","EC:6.5.1.1","DNA ligase 3 [Source:HGNC Symbol;Acc:HGNC:6600]",{"v":0.498611,"d":"0.50"},0,{"v":0.389514,"d":"0.39"},0,{"v":0.001731,"d":"0.00"},0,{"v":513.070479491623,"d":"513.07"},{"v":9.00301320942559,"d":"9.00"},{"v":0.00264274810744688,"d":"0.00"},{"v":0.14266127599338,"d":"0.14"},"up","yes"]
[44556,0,"chr12","-",57095408,57111362,"ENST00000300134",22,3963,"ENSG00000166888","STAT6","GO:0000122(negative regulation of transcription by RNA polymerase II);GO:0000790(nuclear chromatin);GO:0000977(RNA polymerase II regulatory region sequence-specific DNA binding);GO:0000978(RNA polymerase II proximal promoter sequence-specific DNA binding);GO:0000981(DNA-binding transcription factor activity, RNA polymerase II-specific);GO:0001228(DNA-binding transcription activator activity, RNA polymerase II-specific);GO:0002296(T-helper 1 cell lineage commitment);GO:0002829(negative regulation of type 2 immune response);GO:0003677(DNA binding);GO:0003700(DNA-binding transcription factor activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0006355(regulation of transcription, DNA-templated);GO:0006357(regulation of transcription by RNA polymerase II);GO:0007165(signal transduction);GO:0019221(cytokine-mediated signaling pathway);GO:0019903(protein phosphatase binding);GO:0031965(nuclear membrane);GO:0032481(positive regulation of type I interferon production);GO:0033598(mammary gland epithelial cell proliferation);GO:0034097(response to cytokine);GO:0035771(interleukin-4-mediated signaling pathway);GO:0042127(regulation of cell population proliferation);GO:0042802(identical protein binding);GO:0043565(sequence-specific DNA binding);GO:0045121(membrane raft);GO:0045944(positive regulation of transcription by RNA polymerase II);GO:0048295(positive regulation of isotype switching to IgE isotypes);GO:0060443(mammary gland morphogenesis);GO:0070301(cellular response to hydrogen peroxide);GO:0120162(positive regulation of cold-induced thermogenesis);GO:1902170(cellular response to reactive nitrogen species)","04217(Necroptosis);04630(Jak-STAT signaling pathway);04658(Th1 and Th2 cell differentiation);04659(Th17 cell differentiation);05161(Hepatitis B);05200(Pathways in cancer);05321(Inflammatory bowel disease (IBD))","NA","NA","signal transducer and activator of transcription 6 [Source:HGNC Symbol;Acc:HGNC:11368]",{"v":0.340807,"d":"0.34"},{"v":0.234133,"d":"0.23"},{"v":0.269145,"d":"0.27"},{"v":20.063618,"d":"20.06"},{"v":0.160423,"d":"0.16"},{"v":0.166904,"d":"0.17"},{"v":0.0413950898303144,"d":"0.04"},{"v":-4.594396540349,"d":"-4.59"},{"v":0.00267344270236457,"d":"0.00"},{"v":0.143914746657254,"d":"0.14"},"down","yes"]
[89201,0,"chr17","-",64542295,64661897,"ENST00000582081",19,5892,"ENSG00000108854","SMURF2","GO:0000122(negative regulation of transcription by RNA polymerase II);GO:0000151(ubiquitin ligase complex);GO:0000209(protein polyubiquitination);GO:0004842(ubiquitin-protein transferase activity);GO:0005160(transforming growth factor beta receptor binding);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0006511(ubiquitin-dependent protein catabolic process);GO:0016020(membrane);GO:0016567(protein ubiquitination);GO:0016579(protein deubiquitination);GO:0016607(nuclear speck);GO:0016740(transferase activity);GO:0017015(regulation of transforming growth factor beta receptor signaling pathway);GO:0030509(BMP signaling pathway);GO:0030512(negative regulation of transforming growth factor beta receptor signaling pathway);GO:0030514(negative regulation of BMP signaling pathway);GO:0030579(ubiquitin-dependent SMAD protein catabolic process);GO:0042802(identical protein binding);GO:0043161(proteasome-mediated ubiquitin-dependent protein catabolic process);GO:0045121(membrane raft);GO:0045732(positive regulation of protein catabolic process);GO:0045892(negative regulation of transcription, DNA-templated);GO:0046332(SMAD binding);GO:0060071(Wnt signaling pathway, planar cell polarity pathway);GO:0061630(ubiquitin protein ligase activity);GO:0090263(positive regulation of canonical Wnt signaling pathway);GO:1901165(positive regulation of trophoblast cell migration)","04120(Ubiquitin mediated proteolysis);04144(Endocytosis);04340(Hedgehog signaling pathway);04350(TGF-beta signaling pathway)","K04678","EC:2.3.2.26","SMAD specific E3 ubiquitin protein ligase 2 [Source:HGNC Symbol;Acc:HGNC:16809]",{"v":0.013713,"d":"0.01"},{"v":0.024343,"d":"0.02"},{"v":0.445851,"d":"0.45"},{"v":0.039797,"d":"0.04"},{"v":6.291161,"d":"6.29"},{"v":7.155152,"d":"7.16"},{"v":0.0358818814320809,"d":"0.04"},{"v":-4.80060065120178,"d":"-4.80"},{"v":0.00267389083384658,"d":"0.00"},{"v":0.143914746657254,"d":"0.14"},"down","yes"]
[102116,0,"chr19","-",32978592,33064888,"ENST00000254260",15,3501,"ENSG00000131941","RHPN2","GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0007165(signal transduction);GO:0048471(perinuclear region of cytoplasm)","NA","NA","NA","rhophilin Rho GTPase binding protein 2 [Source:HGNC Symbol;Acc:HGNC:19974]",{"v":0.091414,"d":"0.09"},{"v":0.070121,"d":"0.07"},{"v":0.062516,"d":"0.06"},{"v":1.110836,"d":"1.11"},{"v":0.161794,"d":"0.16"},{"v":1.369901,"d":"1.37"},{"v":0.0847865171685781,"d":"0.08"},{"v":-3.56002132546449,"d":"-3.56"},{"v":0.00267955857881474,"d":"0.00"},{"v":0.144006454391035,"d":"0.14"},"down","yes"]
[119409,0,"chr2","-",174562204,174682883,"ENST00000359761",8,2003,"ENSG00000115935","WIPF1","GO:0000147(actin cortical patch assembly);GO:0001726(ruffle);GO:0003779(actin binding);GO:0005515(protein binding);GO:0005522(profilin binding);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005856(cytoskeleton);GO:0005884(actin filament);GO:0006897(endocytosis);GO:0008154(actin polymerization or depolymerization);GO:0015629(actin cytoskeleton);GO:0017124(SH3 domain binding);GO:0030048(actin filament-based movement);GO:0030479(actin cortical patch);GO:0031410(cytoplasmic vesicle);GO:0038096(Fc-gamma receptor signaling pathway involved in phagocytosis);GO:0042995(cell projection);GO:0051015(actin filament binding);GO:0051127(positive regulation of actin nucleation);GO:0051666(actin cortical patch localization);GO:0051707(response to other organism);GO:0065003(protein-containing complex assembly)","04144(Endocytosis)","K19475","NA","WAS/WASL interacting protein family member 1 [Source:HGNC Symbol;Acc:HGNC:12736]",{"v":0.017064,"d":"0.02"},{"v":0.020538,"d":"0.02"},{"v":0.016288,"d":"0.02"},{"v":0.445883,"d":"0.45"},{"v":0.393375,"d":"0.39"},{"v":0.447371,"d":"0.45"},{"v":0.0418846458458499,"d":"0.04"},{"v":-4.57743471486437,"d":"-4.58"},{"v":0.00268464295116906,"d":"0.00"},{"v":0.144066585547965,"d":"0.14"},"down","yes"]
[33837,0,"chr11","+",72227881,72239105,"ENST00000538751",27,4656,"ENSG00000165458","INPPL1","GO:0001958(endochondral ossification);GO:0002376(immune system process);GO:0003779(actin binding);GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0005794(Golgi apparatus);GO:0005829(cytosol);GO:0005856(cytoskeleton);GO:0005886(plasma membrane);GO:0006006(glucose metabolic process);GO:0006661(phosphatidylinositol biosynthetic process);GO:0006897(endocytosis);GO:0007015(actin filament organization);GO:0007155(cell adhesion);GO:0008285(negative regulation of cell population proliferation);GO:0009791(post-embryonic development);GO:0010629(negative regulation of gene expression);GO:0016020(membrane);GO:0016787(hydrolase activity);GO:0017124(SH3 domain binding);GO:0019221(cytokine-mediated signaling pathway);GO:0030027(lamellipodium);GO:0030175(filopodium);GO:0032868(response to insulin);GO:0042169(SH2 domain binding);GO:0042995(cell projection);GO:0043647(inositol phosphate metabolic process);GO:0044255(cellular lipid metabolic process);GO:0046856(phosphatidylinositol dephosphorylation);GO:0097178(ruffle assembly)","00562(Inositol phosphate metabolism);04070(Phosphatidylinositol signaling system);04662(B cell receptor signaling pathway);04666(Fc gamma R-mediated phagocytosis);04910(Insulin signaling pathway)","K15909","EC:3.1.3.86","inositol polyphosphate phosphatase like 1 [Source:HGNC Symbol;Acc:HGNC:6080]",{"v":3.123219,"d":"3.12"},{"v":12.812554,"d":"12.81"},{"v":14.047987,"d":"14.05"},{"v":2.610224,"d":"2.61"},{"v":0.390555,"d":"0.39"},{"v":1.254793,"d":"1.25"},{"v":7.04576494064723,"d":"7.05"},{"v":2.81675634474214,"d":"2.82"},{"v":0.00269541158932325,"d":"0.00"},{"v":0.144431125427896,"d":"0.14"},"up","yes"]
[119179,0,"chr2","+",171434251,171485048,"ENST00000539783",12,5623,"ENSG00000115827","DCAF17","GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005730(nucleolus);GO:0005829(cytosol);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016567(protein ubiquitination);GO:0043687(post-translational protein modification);GO:0080008(Cul4-RING E3 ubiquitin ligase complex)","NA","NA","NA","DDB1 and CUL4 associated factor 17 [Source:HGNC Symbol;Acc:HGNC:25784]",0,{"v":0.216998,"d":"0.22"},{"v":0.38651,"d":"0.39"},{"v":3.0027,"d":"3.00"},{"v":3.734384,"d":"3.73"},{"v":3.955473,"d":"3.96"},{"v":0.0564418782149116,"d":"0.06"},{"v":-4.14709019251543,"d":"-4.15"},{"v":0.00270476566740231,"d":"0.00"},{"v":0.144718905297092,"d":"0.14"},"down","yes"]
[31284,0,"chr11","-",62559603,62577321,"ENST00000526409",13,1954,"ENSG00000255508","AP002990","GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0003730(mRNA 3'-UTR binding);GO:0005634(nucleus);GO:0006378(mRNA polyadenylation);GO:0050265(RNA uridylyltransferase activity)","NA","NA","NA","novel transcript",{"v":6.966368,"d":"6.97"},{"v":9.143215,"d":"9.14"},{"v":148.841156,"d":"148.84"},{"v":5.032804,"d":"5.03"},{"v":0.902976,"d":"0.90"},{"v":8.268239,"d":"8.27"},{"v":11.6129624298588,"d":"11.61"},{"v":3.5376641409662,"d":"3.54"},{"v":0.00272885978753238,"d":"0.00"},{"v":0.145793347178016,"d":"0.15"},"up","yes"]
[20138,0,"chr10","-",30844772,30999517,"ENST00000538351",8,3284,"ENSG00000183621","ZNF438","GO:0000981(DNA-binding transcription factor activity, RNA polymerase II-specific);GO:0003676(nucleic acid binding);GO:0003677(DNA binding);GO:0003700(DNA-binding transcription factor activity);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0043565(sequence-specific DNA binding);GO:0045892(negative regulation of transcription, DNA-templated);GO:0045893(positive regulation of transcription, DNA-templated);GO:0045944(positive regulation of transcription by RNA polymerase II);GO:0046872(metal ion binding)","NA","NA","NA","zinc finger protein 438 [Source:HGNC Symbol;Acc:HGNC:21029]",{"v":1.073018,"d":"1.07"},{"v":0.21111,"d":"0.21"},{"v":1.310155,"d":"1.31"},{"v":0.114028,"d":"0.11"},{"v":0.057459,"d":"0.06"},{"v":0.020254,"d":"0.02"},{"v":13.530142223103,"d":"13.53"},{"v":3.75810509927846,"d":"3.76"},{"v":0.00276366180597081,"d":"0.00"},{"v":0.147435878723817,"d":"0.15"},"up","yes"]
[91543,0,"chr17","-",81228277,81239041,"ENST00000573295",11,2552,"ENSG00000167302","TEPSIN","GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0005794(Golgi apparatus);GO:0005829(cytosol);GO:0016020(membrane);GO:0016607(nuclear speck);GO:0030124(AP-4 adaptor complex);GO:0030662(coated vesicle membrane);GO:0031312(extrinsic component of organelle membrane);GO:0031410(cytoplasmic vesicle);GO:0031965(nuclear membrane);GO:0032588(trans-Golgi network membrane)","NA","NA","NA","TEPSIN, adaptor related protein complex 4 accessory protein [Source:HGNC Symbol;Acc:HGNC:26458]",{"v":0.019928,"d":"0.02"},{"v":0.000431,"d":"0.00"},{"v":0.053752,"d":"0.05"},{"v":0.892341,"d":"0.89"},{"v":0.867553,"d":"0.87"},{"v":0.100868,"d":"0.10"},{"v":0.0398283068979268,"d":"0.04"},{"v":-4.65006203776236,"d":"-4.65"},{"v":0.00280013391489446,"d":"0.00"},{"v":0.149162558838879,"d":"0.15"},"down","yes"]
[121723,0,"chr2","-",215360440,215436067,"ENST00000421182",45,8103,"ENSG00000115414","FN1","GO:0001525(angiogenesis);GO:0001932(regulation of protein phosphorylation);GO:0002020(protease binding);GO:0002576(platelet degranulation);GO:0005102(signaling receptor binding);GO:0005178(integrin binding);GO:0005201(extracellular matrix structural constituent);GO:0005515(protein binding);GO:0005518(collagen binding);GO:0005576(extracellular region);GO:0005577(fibrinogen complex);GO:0005604(basement membrane);GO:0005615(extracellular space);GO:0005788(endoplasmic reticulum lumen);GO:0005793(endoplasmic reticulum-Golgi intermediate compartment);GO:0006953(acute-phase response);GO:0007044(cell-substrate junction assembly);GO:0007155(cell adhesion);GO:0007160(cell-matrix adhesion);GO:0007161(calcium-independent cell-matrix adhesion);GO:0008022(protein C-terminus binding);GO:0008201(heparin binding);GO:0008284(positive regulation of cell population proliferation);GO:0008360(regulation of cell shape);GO:0009611(response to wounding);GO:0010628(positive regulation of gene expression);GO:0010952(positive regulation of peptidase activity);GO:0016324(apical plasma membrane);GO:0016504(peptidase activator activity);GO:0018149(peptide cross-linking);GO:0019221(cytokine-mediated signaling pathway);GO:0019899(enzyme binding);GO:0030198(extracellular matrix organization);GO:0031012(extracellular matrix);GO:0031093(platelet alpha granule lumen);GO:0033622(integrin activation);GO:0034446(substrate adhesion-dependent cell spreading);GO:0035987(endodermal cell differentiation);GO:0042060(wound healing);GO:0042802(identical protein binding);GO:0043394(proteoglycan binding);GO:0043687(post-translational protein modification);GO:0044267(cellular protein metabolic process);GO:0045773(positive regulation of axon extension);GO:0048146(positive regulation of fibroblast proliferation);GO:0050900(leukocyte migration);GO:0051087(chaperone binding);GO:0051702(interaction with symbiont);GO:0052047(interaction with other organism via secreted substance involved in symbiotic interaction);GO:0062023(collagen-containing extracellular matrix);GO:0070062(extracellular exosome);GO:0070372(regulation of ERK1 and ERK2 cascade);GO:0072562(blood microparticle);GO:0097718(disordered domain specific binding);GO:1901166(neural crest cell migration involved in autonomic nervous system development);GO:1904237(positive regulation of substrate-dependent cell migration, cell attachment to substrate);GO:2001202(negative regulation of transforming growth factor-beta secretion)","04151(PI3K-Akt signaling pathway);04510(Focal adhesion);04512(ECM-receptor interaction);04810(Regulation of actin cytoskeleton);04933(AGE-RAGE signaling pathway in diabetic complications);05100(Bacterial invasion of epithelial cells);05146(Amoebiasis);05165(Human papillomavirus infection);05200(Pathways in cancer);05205(Proteoglycans in cancer);05222(Small cell lung cancer)","NA","NA","fibronectin 1 [Source:HGNC Symbol;Acc:HGNC:3778]",{"v":17.372522,"d":"17.37"},{"v":2.064336,"d":"2.06"},{"v":10.320745,"d":"10.32"},{"v":27.056854,"d":"27.06"},{"v":108.220604,"d":"108.22"},{"v":39.425228,"d":"39.43"},{"v":0.170332830486647,"d":"0.17"},{"v":-2.55357156347981,"d":"-2.55"},{"v":0.00284759151465274,"d":"0.00"},{"v":0.151420360404334,"d":"0.15"},"down","yes"]
[55645,0,"chr14","-",30893804,31026379,"ENST00000357479",18,4195,"ENSG00000196792","STRN3","GO:0005515(protein binding);GO:0005516(calmodulin binding);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0005794(Golgi apparatus);GO:0005886(plasma membrane);GO:0016020(membrane);GO:0017048(Rho GTPase binding);GO:0030425(dendrite);GO:0032355(response to estradiol);GO:0032991(protein-containing complex);GO:0033147(negative regulation of intracellular estrogen receptor signaling pathway);GO:0043025(neuronal cell body);GO:0044877(protein-containing complex binding);GO:0045892(negative regulation of transcription, DNA-templated);GO:0051721(protein phosphatase 2A binding);GO:0070016(armadillo repeat domain binding);GO:0090443(FAR/SIN/STRIPAK complex)","NA","K17608","NA","striatin 3 [Source:HGNC Symbol;Acc:HGNC:15720]",{"v":1.396976,"d":"1.40"},{"v":0.092467,"d":"0.09"},{"v":4.632648,"d":"4.63"},{"v":0.16557,"d":"0.17"},{"v":0.051499,"d":"0.05"},{"v":0.136707,"d":"0.14"},{"v":17.304992424585,"d":"17.30"},{"v":4.11311640483823,"d":"4.11"},{"v":0.00285085401917325,"d":"0.00"},{"v":0.151420360404334,"d":"0.15"},"up","yes"]
[163149,0,"chr5","-",138553756,138575724,"ENST00000649126",17,4727,"ENSG00000113013","HSPA9","GO:0000166(nucleotide binding);GO:0003723(RNA binding);GO:0005515(protein binding);GO:0005524(ATP binding);GO:0005634(nucleus);GO:0005730(nucleolus);GO:0005737(cytoplasm);GO:0005739(mitochondrion);GO:0005759(mitochondrial matrix);GO:0005925(focal adhesion);GO:0006457(protein folding);GO:0006611(protein export from nucleus);GO:0006986(response to unfolded protein);GO:0016226(iron-sulfur cluster assembly);GO:0016887(ATPase activity);GO:0019899(enzyme binding);GO:0030218(erythrocyte differentiation);GO:0031072(heat shock protein binding);GO:0031625(ubiquitin protein ligase binding);GO:0034605(cellular response to heat);GO:0034620(cellular response to unfolded protein);GO:0035722(interleukin-12-mediated signaling pathway);GO:0042026(protein refolding);GO:0042623(ATPase activity, coupled);GO:0042645(mitochondrial nucleoid);GO:0043066(negative regulation of apoptotic process);GO:0044183(protein folding chaperone);GO:0045646(regulation of erythrocyte differentiation);GO:0045647(negative regulation of erythrocyte differentiation);GO:0051082(unfolded protein binding);GO:0051085(chaperone cofactor-dependent protein refolding);GO:0051787(misfolded protein binding);GO:0070062(extracellular exosome);GO:1902037(negative regulation of hematopoietic stem cell differentiation);GO:1903707(negative regulation of hemopoiesis)","03018(RNA degradation);05152(Tuberculosis)","K04043","NA","heat shock protein family A (Hsp70) member 9 [Source:HGNC Symbol;Acc:HGNC:5244]",{"v":0.571412,"d":"0.57"},{"v":5.050837,"d":"5.05"},{"v":0.647817,"d":"0.65"},{"v":37.648193,"d":"37.65"},{"v":36.239296,"d":"36.24"},{"v":0.743145,"d":"0.74"},{"v":0.0840146420302419,"d":"0.08"},{"v":-3.57321540779317,"d":"-3.57"},{"v":0.0028874752160645,"d":"0.00"},{"v":0.153141568758574,"d":"0.15"},"down","yes"]
[66871,0,"chr15","-",76348188,76883876,"ENST00000324767",31,4707,"ENSG00000140386","SCAPER","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0005783(endoplasmic reticulum);GO:0005829(cytosol);GO:0008270(zinc ion binding);GO:0046872(metal ion binding)","NA","NA","NA","S-phase cyclin A associated protein in the ER [Source:HGNC Symbol;Acc:HGNC:13081]",{"v":0.638256,"d":"0.64"},{"v":0.318781,"d":"0.32"},{"v":1.068299,"d":"1.07"},{"v":0.022368,"d":"0.02"},0,{"v":0.07777,"d":"0.08"},{"v":20.2254488805448,"d":"20.23"},{"v":4.33809981685286,"d":"4.34"},{"v":0.0029020648927488,"d":"0.00"},{"v":0.153690987687411,"d":"0.15"},"up","yes"]
[86960,0,"chr17","+",47531282,47592680,"ENST00000527298",12,1569,"ENSG00000141279","NPEPPS","GO:0000209(protein polyubiquitination);GO:0004177(aminopeptidase activity);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0006508(proteolysis);GO:0008233(peptidase activity);GO:0008237(metallopeptidase activity);GO:0008270(zinc ion binding);GO:0016787(hydrolase activity);GO:0042277(peptide binding);GO:0043171(peptide catabolic process);GO:0046872(metal ion binding);GO:0070006(metalloaminopeptidase activity);GO:0070062(extracellular exosome);GO:0071456(cellular response to hypoxia);GO:1903955(positive regulation of protein targeting to mitochondrion)","NA","K08776","EC:3.4.11.-","aminopeptidase puromycin sensitive [Source:HGNC Symbol;Acc:HGNC:7900]",{"v":0.123484,"d":"0.12"},{"v":2.351718,"d":"2.35"},{"v":1.842303,"d":"1.84"},{"v":0.048174,"d":"0.05"},{"v":0.164718,"d":"0.16"},{"v":0.020758,"d":"0.02"},{"v":18.4785148726728,"d":"18.48"},{"v":4.20777690619068,"d":"4.21"},{"v":0.00291350586287559,"d":"0.00"},{"v":0.154072296940713,"d":"0.15"},"up","yes"]
[12008,0,"chr1","-",155195590,155207981,"ENST00000541576",22,3200,"ENSG00000169231","THBS3","GO:0003417(growth plate cartilage development);GO:0005201(extracellular matrix structural constituent);GO:0005509(calcium ion binding);GO:0005576(extracellular region);GO:0007155(cell adhesion);GO:0007160(cell-matrix adhesion);GO:0008201(heparin binding);GO:0043931(ossification involved in bone maturation);GO:0048471(perinuclear region of cytoplasm);GO:0060346(bone trabecula formation);GO:0062023(collagen-containing extracellular matrix)","04145(Phagosome);04151(PI3K-Akt signaling pathway);04510(Focal adhesion);04512(ECM-receptor interaction);05144(Malaria);05165(Human papillomavirus infection)","K04659","NA","thrombospondin 3 [Source:HGNC Symbol;Acc:HGNC:11787]",{"v":4.756645,"d":"4.76"},{"v":0.472809,"d":"0.47"},{"v":6.549696,"d":"6.55"},{"v":0.139908,"d":"0.14"},0,{"v":0.32333,"d":"0.32"},{"v":25.4278578182273,"d":"25.43"},{"v":4.66833802151635,"d":"4.67"},{"v":0.00292352391724196,"d":"0.00"},{"v":0.154362701587872,"d":"0.15"},"up","yes"]
[50742,0,"chr13","-",28385548,28495079,"ENST00000615840",13,6453,"ENSG00000102755","FLT1","GO:0000166(nucleotide binding);GO:0001525(angiogenesis);GO:0002040(sprouting angiogenesis);GO:0002548(monocyte chemotaxis);GO:0004672(protein kinase activity);GO:0004713(protein tyrosine kinase activity);GO:0004714(transmembrane receptor protein tyrosine kinase activity);GO:0005021(vascular endothelial growth factor-activated receptor activity);GO:0005515(protein binding);GO:0005524(ATP binding);GO:0005576(extracellular region);GO:0005615(extracellular space);GO:0005737(cytoplasm);GO:0005768(endosome);GO:0005886(plasma membrane);GO:0005887(integral component of plasma membrane);GO:0005925(focal adhesion);GO:0006468(protein phosphorylation);GO:0006935(chemotaxis);GO:0007169(transmembrane receptor protein tyrosine kinase signaling pathway);GO:0007275(multicellular organism development);GO:0008284(positive regulation of cell population proliferation);GO:0010863(positive regulation of phospholipase C activity);GO:0014068(positive regulation of phosphatidylinositol 3-kinase signaling);GO:0015629(actin cytoskeleton);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0016477(cell migration);GO:0016740(transferase activity);GO:0018108(peptidyl-tyrosine phosphorylation);GO:0019838(growth factor binding);GO:0030154(cell differentiation);GO:0030335(positive regulation of cell migration);GO:0030949(positive regulation of vascular endothelial growth factor receptor signaling pathway);GO:0035924(cellular response to vascular endothelial growth factor stimulus);GO:0036323(vascular endothelial growth factor receptor-1 signaling pathway);GO:0036326(VEGF-A-activated receptor activity);GO:0036327(VEGF-B-activated receptor activity);GO:0036332(placental growth factor-activated receptor activity);GO:0038084(vascular endothelial growth factor signaling pathway);GO:0038085(vascular endothelial growth factor binding);GO:0043235(receptor complex);GO:0043406(positive regulation of MAP kinase activity);GO:0043410(positive regulation of MAPK cascade);GO:0043552(positive regulation of phosphatidylinositol 3-kinase activity);GO:0045766(positive regulation of angiogenesis);GO:0046777(protein autophosphorylation);GO:0048010(vascular endothelial growth factor receptor signaling pathway);GO:0048514(blood vessel morphogenesis);GO:0048598(embryonic morphogenesis);GO:0070374(positive regulation of ERK1 and ERK2 cascade);GO:1905563(negative regulation of vascular endothelial cell proliferation)","04010(MAPK signaling pathway);04014(Ras signaling pathway);04015(Rap1 signaling pathway);04066(HIF-1 signaling pathway);04151(PI3K-Akt signaling pathway);04510(Focal adhesion);05202(Transcriptional misregulation in cancer);05323(Rheumatoid arthritis)","NA","NA","fms related tyrosine kinase 1 [Source:HGNC Symbol;Acc:HGNC:3763]",0,{"v":0.036829,"d":"0.04"},0,{"v":0.43744,"d":"0.44"},{"v":0.501217,"d":"0.50"},{"v":0.195794,"d":"0.20"},{"v":0.0324641610787949,"d":"0.03"},{"v":-4.94500826126903,"d":"-4.95"},{"v":0.00292749522141602,"d":"0.00"},{"v":0.154362701587872,"d":"0.15"},"down","yes"]
[10497,0,"chr1","+",147242673,147295724,"ENST00000652616",22,2827,"ENSG00000131778","CHD1L","GO:0000166(nucleotide binding);GO:0000717(nucleotide-excision repair, DNA duplex unwinding);GO:0004003(ATP-dependent DNA helicase activity);GO:0004386(helicase activity);GO:0005515(protein binding);GO:0005524(ATP binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0006281(DNA repair);GO:0006293(nucleotide-excision repair, preincision complex stabilization);GO:0006294(nucleotide-excision repair, preincision complex assembly);GO:0006295(nucleotide-excision repair, DNA incision, 3'-to lesion);GO:0006296(nucleotide-excision repair, DNA incision, 5'-to lesion);GO:0006338(chromatin remodeling);GO:0006974(cellular response to DNA damage stimulus);GO:0016787(hydrolase activity);GO:0016887(ATPase activity);GO:0032508(DNA duplex unwinding);GO:0033683(nucleotide-excision repair, DNA incision);GO:0043044(ATP-dependent chromatin remodeling);GO:0070911(global genome nucleotide-excision repair)","NA","K20092","EC:3.6.4.12","chromodomain helicase DNA binding protein 1 like [Source:HGNC Symbol;Acc:HGNC:1916]",{"v":0.531064,"d":"0.53"},{"v":1.98477,"d":"1.98"},0,0,{"v":0.020147,"d":"0.02"},{"v":0.009318,"d":"0.01"},{"v":85.3838113015442,"d":"85.38"},{"v":6.41589065690036,"d":"6.42"},{"v":0.00294275249201609,"d":"0.00"},{"v":0.154775492773681,"d":"0.15"},"up","yes"]
[168919,0,"chr6","-",31271099,31272090,"ENST00000484378",2,862,"ENSG00000204525","HLA-C","GO:0000139(Golgi membrane);GO:0002376(immune system process);GO:0002474(antigen processing and presentation of peptide antigen via MHC class I);GO:0002479(antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent);GO:0002480(antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent);GO:0005515(protein binding);GO:0005783(endoplasmic reticulum);GO:0005794(Golgi apparatus);GO:0005886(plasma membrane);GO:0006955(immune response);GO:0009986(cell surface);GO:0012507(ER to Golgi transport vesicle membrane);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0019882(antigen processing and presentation);GO:0030667(secretory granule membrane);GO:0030670(phagocytic vesicle membrane);GO:0031901(early endosome membrane);GO:0042605(peptide antigen binding);GO:0042612(MHC class I protein complex);GO:0043312(neutrophil degranulation);GO:0050776(regulation of immune response);GO:0055038(recycling endosome membrane);GO:0060333(interferon-gamma-mediated signaling pathway);GO:0060337(type I interferon signaling pathway);GO:0070062(extracellular exosome);GO:0071556(integral component of lumenal side of endoplasmic reticulum membrane)","04144(Endocytosis);04145(Phagosome);04218(Cellular senescence);04514(Cell adhesion molecules (CAMs));04612(Antigen processing and presentation);04650(Natural killer cell mediated cytotoxicity);04940(Type I diabetes mellitus);05163(Human cytomegalovirus infection);05165(Human papillomavirus infection);05166(Human T-cell leukemia virus 1 infection);05167(Kaposi sarcoma-associated herpesvirus infection);05168(Herpes simplex virus 1 infection);05169(Epstein-Barr virus infection);05170(Human immunodeficiency virus 1 infection);05203(Viral carcinogenesis);05320(Autoimmune thyroid disease);05330(Allograft rejection);05332(Graft-versus-host disease);05416(Viral myocarditis)","K06751","NA","major histocompatibility complex, class I, C [Source:HGNC Symbol;Acc:HGNC:4933]",{"v":0.542094,"d":"0.54"},{"v":1.084276,"d":"1.08"},{"v":0.798694,"d":"0.80"},{"v":19.733631,"d":"19.73"},{"v":0.608573,"d":"0.61"},{"v":12.282491,"d":"12.28"},{"v":0.0743321585075355,"d":"0.07"},{"v":-3.74986968719496,"d":"-3.75"},{"v":0.00294384435746252,"d":"0.00"},{"v":0.154775492773681,"d":"0.15"},"down","yes"]
[51152,0,"chr13","-",37562583,37598844,"ENST00000541179",21,3214,"ENSG00000133110","POSTN","GO:0001666(response to hypoxia);GO:0001953(negative regulation of cell-matrix adhesion);GO:0003073(regulation of systemic arterial blood pressure);GO:0005201(extracellular matrix structural constituent);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0005615(extracellular space);GO:0005737(cytoplasm);GO:0005794(Golgi apparatus);GO:0005802(trans-Golgi network);GO:0007155(cell adhesion);GO:0008201(heparin binding);GO:0008593(regulation of Notch signaling pathway);GO:0009612(response to mechanical stimulus);GO:0009888(tissue development);GO:0014850(response to muscle activity);GO:0014911(positive regulation of smooth muscle cell migration);GO:0030198(extracellular matrix organization);GO:0031012(extracellular matrix);GO:0031594(neuromuscular junction);GO:0032355(response to estradiol);GO:0042060(wound healing);GO:0044344(cellular response to fibroblast growth factor stimulus);GO:0046872(metal ion binding);GO:0050839(cell adhesion molecule binding);GO:0062023(collagen-containing extracellular matrix);GO:0071307(cellular response to vitamin K);GO:0071356(cellular response to tumor necrosis factor);GO:0071560(cellular response to transforming growth factor beta stimulus);GO:1900025(negative regulation of substrate adhesion-dependent cell spreading);GO:1904209(positive regulation of chemokine (C-C motif) ligand 2 secretion);GO:1990138(neuron projection extension);GO:1990523(bone regeneration)","NA","NA","NA","periostin [Source:HGNC Symbol;Acc:HGNC:16953]",{"v":76.183067,"d":"76.18"},{"v":75.151512,"d":"75.15"},{"v":68.450409,"d":"68.45"},{"v":19.001455,"d":"19.00"},{"v":19.620565,"d":"19.62"},{"v":19.486458,"d":"19.49"},{"v":3.78232222843627,"d":"3.78"},{"v":1.91927227644586,"d":"1.92"},{"v":0.00294890029181512,"d":"0.00"},{"v":0.154817265320294,"d":"0.15"},"up","yes"]
[11899,0,"chr1","+",155051286,155062758,"ENST00000526491",23,3091,"ENSG00000143537","ADAM15","GO:0001525(angiogenesis);GO:0001669(acrosomal vesicle);GO:0001953(negative regulation of cell-matrix adhesion);GO:0002418(immune response to tumor cell);GO:0004222(metalloendopeptidase activity);GO:0005178(integrin binding);GO:0005515(protein binding);GO:0005886(plasma membrane);GO:0005912(adherens junction);GO:0005929(cilium);GO:0006508(proteolysis);GO:0007155(cell adhesion);GO:0007160(cell-matrix adhesion);GO:0007229(integrin-mediated signaling pathway);GO:0008233(peptidase activity);GO:0008237(metallopeptidase activity);GO:0008584(male gonad development);GO:0009986(cell surface);GO:0012505(endomembrane system);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016787(hydrolase activity);GO:0017124(SH3 domain binding);GO:0022617(extracellular matrix disassembly);GO:0030054(cell junction);GO:0030198(extracellular matrix organization);GO:0030308(negative regulation of cell growth);GO:0030336(negative regulation of cell migration);GO:0030574(collagen catabolic process);GO:0031410(cytoplasmic vesicle);GO:0031514(motile cilium);GO:0042246(tissue regeneration);GO:0042995(cell projection);GO:0045087(innate immune response);GO:0046872(metal ion binding);GO:0060317(cardiac epithelial to mesenchymal transition);GO:0070062(extracellular exosome);GO:1900121(negative regulation of receptor binding);GO:1904628(cellular response to phorbol 13-acetate 12-myristate);GO:1990910(response to hypobaric hypoxia)","NA","K06836","EC:3.4.24.-","ADAM metallopeptidase domain 15 [Source:HGNC Symbol;Acc:HGNC:193]",{"v":0.054004,"d":"0.05"},{"v":0.520979,"d":"0.52"},{"v":0.2702,"d":"0.27"},0,0,{"v":0.014775,"d":"0.01"},{"v":57.2035871404399,"d":"57.20"},{"v":5.83803371369973,"d":"5.84"},{"v":0.00299803534421101,"d":"0.00"},{"v":0.157169731681365,"d":"0.16"},"up","yes"]
[34073,0,"chr11","-",73729464,73761017,"ENST00000541795",2,1812,"ENSG00000175582","RAB6A","GO:0000139(Golgi membrane);GO:0000166(nucleotide binding);GO:0003924(GTPase activity);GO:0005515(protein binding);GO:0005525(GTP binding);GO:0005789(endoplasmic reticulum membrane);GO:0005794(Golgi apparatus);GO:0005802(trans-Golgi network);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0006886(intracellular protein transport);GO:0006890(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum);GO:0006891(intra-Golgi vesicle-mediated transport);GO:0015031(protein transport);GO:0016020(membrane);GO:0016032(viral process);GO:0016192(vesicle-mediated transport);GO:0018125(peptidyl-cysteine methylation);GO:0019882(antigen processing and presentation);GO:0019904(protein domain specific binding);GO:0030667(secretory granule membrane);GO:0031410(cytoplasmic vesicle);GO:0031489(myosin V binding);GO:0032482(Rab protein signal transduction);GO:0032588(trans-Golgi network membrane);GO:0034067(protein localization to Golgi apparatus);GO:0042147(retrograde transport, endosome to Golgi);GO:0043312(neutrophil degranulation);GO:0070062(extracellular exosome);GO:0070381(endosome to plasma membrane transport vesicle);GO:0072385(minus-end-directed organelle transport along microtubule)","NA","K07893","NA","RAB6A, member RAS oncogene family [Source:HGNC Symbol;Acc:HGNC:9786]",{"v":2.113284,"d":"2.11"},{"v":2.265545,"d":"2.27"},{"v":0.054043,"d":"0.05"},{"v":0.100198,"d":"0.10"},{"v":0.03146,"d":"0.03"},{"v":0.100072,"d":"0.10"},{"v":19.129469641393,"d":"19.13"},{"v":4.25772497085373,"d":"4.26"},{"v":0.00300973326947604,"d":"0.00"},{"v":0.157555633544762,"d":"0.16"},"up","yes"]
[44474,0,"chr12","-",56712428,56725542,"ENST00000454682",9,6629,"ENSG00000196531","NACA","GO:0003231(cardiac ventricle development);GO:0003677(DNA binding);GO:0003713(transcription coactivator activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005854(nascent polypeptide-associated complex);GO:0006412(translation);GO:0010664(negative regulation of striated muscle cell apoptotic process);GO:0015031(protein transport);GO:0043403(skeletal muscle tissue regeneration);GO:0048633(positive regulation of skeletal muscle tissue growth);GO:0048742(regulation of skeletal muscle fiber development);GO:0061384(heart trabecula morphogenesis);GO:0070062(extracellular exosome);GO:1901227(negative regulation of transcription from RNA polymerase II promoter involved in heart development);GO:1901228(positive regulation of transcription from RNA polymerase II promoter involved in heart development);GO:2000138(positive regulation of cell proliferation involved in heart morphogenesis)","04928(Parathyroid hormone synthesis, secretion and action)","K03626","NA","nascent polypeptide associated complex subunit alpha [Source:HGNC Symbol;Acc:HGNC:7629]",{"v":0.108114,"d":"0.11"},{"v":0.089491,"d":"0.09"},{"v":0.139891,"d":"0.14"},{"v":0.063413,"d":"0.06"},{"v":9.372266,"d":"9.37"},{"v":0.053427,"d":"0.05"},{"v":0.0355666803595618,"d":"0.04"},{"v":-4.81332986401971,"d":"-4.81"},{"v":0.00301421766268262,"d":"0.00"},{"v":0.157563349187424,"d":"0.16"},"down","yes"]
[84141,0,"chr17","-",32594203,32877144,"ENST00000579584",22,3500,"ENSG00000176658","MYO1D","GO:0000146(microfilament motor activity);GO:0000166(nucleotide binding);GO:0003774(motor activity);GO:0003779(actin binding);GO:0005515(protein binding);GO:0005516(calmodulin binding);GO:0005524(ATP binding);GO:0005737(cytoplasm);GO:0005768(endosome);GO:0005769(early endosome);GO:0005790(smooth endoplasmic reticulum);GO:0005829(cytosol);GO:0005903(brush border);GO:0005938(cell cortex);GO:0010923(negative regulation of phosphatase activity);GO:0015031(protein transport);GO:0016323(basolateral plasma membrane);GO:0016459(myosin complex);GO:0019904(protein domain specific binding);GO:0030424(axon);GO:0030425(dendrite);GO:0030673(axolemma);GO:0030898(actin-dependent ATPase activity);GO:0030900(forebrain development);GO:0031410(cytoplasmic vesicle);GO:0042995(cell projection);GO:0043005(neuron projection);GO:0043025(neuronal cell body);GO:0043204(perikaryon);GO:0043209(myelin sheath);GO:0044853(plasma membrane raft);GO:0048306(calcium-dependent protein binding);GO:0051015(actin filament binding);GO:0051641(cellular localization);GO:0061502(early endosome to recycling endosome transport);GO:0070062(extracellular exosome);GO:0097440(apical dendrite)","NA","K10356","NA","myosin ID [Source:HGNC Symbol;Acc:HGNC:7598]",{"v":0.067981,"d":"0.07"},{"v":0.021543,"d":"0.02"},{"v":0.136729,"d":"0.14"},{"v":3.069937,"d":"3.07"},{"v":0.204855,"d":"0.20"},{"v":0.486943,"d":"0.49"},{"v":0.0601459167113048,"d":"0.06"},{"v":-4.05538939319322,"d":"-4.06"},{"v":0.00302679986878789,"d":"0.00"},{"v":0.157846398255937,"d":"0.16"},"down","yes"]
[111942,0,"chr2","-",44320922,44361806,"ENST00000410081",15,3080,"ENSG00000138078","PREPL","GO:0004252(serine-type endopeptidase activity);GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0005794(Golgi apparatus);GO:0005829(cytosol);GO:0005856(cytoskeleton);GO:0006508(proteolysis);GO:0008233(peptidase activity);GO:0008236(serine-type peptidase activity);GO:0016787(hydrolase activity);GO:0070008(serine-type exopeptidase activity);GO:2000300(regulation of synaptic vesicle exocytosis)","NA","K22582","EC:3.4.21.-","prolyl endopeptidase like [Source:HGNC Symbol;Acc:HGNC:30228]",{"v":0.489699,"d":"0.49"},{"v":11.602738,"d":"11.60"},{"v":2.205988,"d":"2.21"},{"v":0.440359,"d":"0.44"},{"v":0.112725,"d":"0.11"},{"v":0.479482,"d":"0.48"},{"v":13.8474683458491,"d":"13.85"},{"v":3.79155033551254,"d":"3.79"},{"v":0.0030283220364544,"d":"0.00"},{"v":0.157846398255937,"d":"0.16"},"up","yes"]
[200787,0,"chr9","-",137007377,137028915,"ENST00000459850",47,8073,"ENSG00000107331","ABCA2","GO:0000166(nucleotide binding);GO:0005319(lipid transporter activity);GO:0005524(ATP binding);GO:0005764(lysosome);GO:0005765(lysosomal membrane);GO:0005768(endosome);GO:0005815(microtubule organizing center);GO:0006357(regulation of transcription by RNA polymerase II);GO:0006629(lipid metabolic process);GO:0006869(lipid transport);GO:0010008(endosome membrane);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016887(ATPase activity);GO:0031410(cytoplasmic vesicle);GO:0032383(regulation of intracellular cholesterol transport);GO:0042493(response to drug);GO:0042626(ATPase activity, coupled to transmembrane movement of substances);GO:0042632(cholesterol homeostasis);GO:0043190(ATP-binding cassette (ABC) transporter complex);GO:0043231(intracellular membrane-bounded organelle);GO:0048545(response to steroid hormone);GO:0055085(transmembrane transport);GO:0070723(response to cholesterol)","02010(ABC transporters);04142(Lysosome)","NA","NA","ATP binding cassette subfamily A member 2 [Source:HGNC Symbol;Acc:HGNC:32]",{"v":0.02068,"d":"0.02"},0,{"v":0.104793,"d":"0.10"},{"v":0.240556,"d":"0.24"},{"v":0.921897,"d":"0.92"},{"v":1.958414,"d":"1.96"},{"v":0.0402045329070415,"d":"0.04"},{"v":-4.63649802086211,"d":"-4.64"},{"v":0.0030936514121548,"d":"0.00"},{"v":0.161020567053845,"d":"0.16"},"down","yes"]
[2450,0,"chr1","-",20806292,21176888,"ENST00000374935",33,5567,"ENSG00000075151","EIF4G3","GO:0000339(RNA cap binding);GO:0003723(RNA binding);GO:0003729(mRNA binding);GO:0003743(translation initiation factor activity);GO:0005515(protein binding);GO:0005829(cytosol);GO:0006412(translation);GO:0006413(translational initiation);GO:0006417(regulation of translation);GO:0006446(regulation of translational initiation);GO:0008135(translation factor activity, RNA binding);GO:0016281(eukaryotic translation initiation factor 4F complex)","03013(RNA transport);05416(Viral myocarditis)","K03260","NA","eukaryotic translation initiation factor 4 gamma 3 [Source:HGNC Symbol;Acc:HGNC:3298]",{"v":0.039977,"d":"0.04"},{"v":0.412564,"d":"0.41"},{"v":0.805265,"d":"0.81"},{"v":7.471465,"d":"7.47"},{"v":6.860798,"d":"6.86"},{"v":0.459598,"d":"0.46"},{"v":0.0850336546564357,"d":"0.09"},{"v":-3.55582224503696,"d":"-3.56"},{"v":0.00314557445963344,"d":"0.00"},{"v":0.163488869983524,"d":"0.16"},"down","yes"]
[49959,0,"chr12","+",132118146,132131639,"ENST00000475841",7,7090,"ENSG00000185684","EP400P1","NA","NA","NA","NA","EP400 pseudogene 1 [Source:HGNC Symbol;Acc:HGNC:26602]",{"v":0.012834,"d":"0.01"},0,{"v":0.006202,"d":"0.01"},0,{"v":0.286635,"d":"0.29"},{"v":1.090359,"d":"1.09"},{"v":0.0138243158648476,"d":"0.01"},{"v":-6.17664810336996,"d":"-6.18"},{"v":0.00316062578088539,"d":"0.00"},{"v":0.164036478027952,"d":"0.16"},"down","yes"]
[165161,0,"chr5","+",163505626,163519149,"ENST00000523606",6,3210,"ENSG00000038274","MAT2B","GO:0005515(protein binding);GO:0005634(nucleus);GO:0005829(cytosol);GO:0006556(S-adenosylmethionine biosynthetic process);GO:0006730(one-carbon metabolic process);GO:0019899(enzyme binding);GO:0032259(methylation);GO:0048269(methionine adenosyltransferase complex);GO:0048270(methionine adenosyltransferase regulator activity);GO:0050790(regulation of catalytic activity);GO:0070062(extracellular exosome)","00270(Cysteine and methionine metabolism)","K00789","EC:2.5.1.6","methionine adenosyltransferase 2B [Source:HGNC Symbol;Acc:HGNC:6905]",{"v":0.738485,"d":"0.74"},{"v":0.186475,"d":"0.19"},{"v":1.242658,"d":"1.24"},{"v":9.36485,"d":"9.36"},{"v":0.944657,"d":"0.94"},{"v":10.252183,"d":"10.25"},{"v":0.105420225672112,"d":"0.11"},{"v":-3.24577640933991,"d":"-3.25"},{"v":0.00318204631691866,"d":"0.00"},{"v":0.164912614398937,"d":"0.16"},"down","yes"]
[12579,0,"chr1","-",156742109,156751675,"ENST00000357325",6,2309,"ENSG00000143321","HDGF","GO:0000122(negative regulation of transcription by RNA polymerase II);GO:0000166(nucleotide binding);GO:0001222(transcription corepressor binding);GO:0003677(DNA binding);GO:0003714(transcription corepressor activity);GO:0003723(RNA binding);GO:0005576(extracellular region);GO:0005615(extracellular space);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0007165(signal transduction);GO:0008083(growth factor activity);GO:0008201(heparin binding);GO:0008283(cell population proliferation);GO:0009987(cellular process);GO:0010469(regulation of signaling receptor activity);GO:0017053(transcriptional repressor complex);GO:0036498(IRE1-mediated unfolded protein response);GO:0062023(collagen-containing extracellular matrix);GO:0098761(cellular response to interleukin-7)","NA","K16641","NA","heparin binding growth factor [Source:HGNC Symbol;Acc:HGNC:4856]",{"v":61.71312,"d":"61.71"},{"v":56.798412,"d":"56.80"},{"v":4.51097,"d":"4.51"},{"v":6.539122,"d":"6.54"},{"v":6.23433,"d":"6.23"},{"v":6.999756,"d":"7.00"},{"v":6.22167642195439,"d":"6.22"},{"v":2.63730336488501,"d":"2.64"},{"v":0.00319356384528468,"d":"0.00"},{"v":0.165273752847853,"d":"0.17"},"up","yes"]
[19180,0,"chr10","-",12896625,13001713,"ENST00000378825",3,2747,"ENSG00000151468","CCDC3","GO:0005576(extracellular region);GO:0005783(endoplasmic reticulum);GO:0010804(negative regulation of tumor necrosis factor-mediated signaling pathway);GO:0045600(positive regulation of fat cell differentiation);GO:0046889(positive regulation of lipid biosynthetic process)","NA","NA","NA","coiled-coil domain containing 3 [Source:HGNC Symbol;Acc:HGNC:23813]",{"v":0.05951,"d":"0.06"},{"v":0.424314,"d":"0.42"},{"v":0.048018,"d":"0.05"},{"v":1.767041,"d":"1.77"},{"v":2.712382,"d":"2.71"},{"v":1.981508,"d":"1.98"},{"v":0.082316619694592,"d":"0.08"},{"v":-3.60267245013247,"d":"-3.60"},{"v":0.0032123338682594,"d":"0.00"},{"v":0.166008662068085,"d":"0.17"},"down","yes"]
[101033,0,"chr19","-",18531752,18543573,"ENST00000544835",6,1292,"ENSG00000105701","FKBP8","GO:0000413(protein peptidyl-prolyl isomerization);GO:0001708(cell fate specification);GO:0001933(negative regulation of protein phosphorylation);GO:0003755(peptidyl-prolyl cis-trans isomerase activity);GO:0005515(protein binding);GO:0005739(mitochondrion);GO:0005740(mitochondrial envelope);GO:0005783(endoplasmic reticulum);GO:0005829(cytosol);GO:0006915(apoptotic process);GO:0007224(smoothened signaling pathway);GO:0009953(dorsal/ventral pattern formation);GO:0010468(regulation of gene expression);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016032(viral process);GO:0016853(isomerase activity);GO:0021904(dorsal/ventral neural tube patterning);GO:0021915(neural tube development);GO:0030176(integral component of endoplasmic reticulum membrane);GO:0030510(regulation of BMP signaling pathway);GO:0030513(positive regulation of BMP signaling pathway);GO:0031966(mitochondrial membrane);GO:0032991(protein-containing complex);GO:0035264(multicellular organism growth);GO:0035556(intracellular signal transduction);GO:0042802(identical protein binding);GO:0043010(camera-type eye development);GO:0043066(negative regulation of apoptotic process);GO:0046872(metal ion binding);GO:0097718(disordered domain specific binding)","NA","K09574","EC:5.2.1.8","FKBP prolyl isomerase 8 [Source:HGNC Symbol;Acc:HGNC:3724]",{"v":0.464265,"d":"0.46"},{"v":0.016645,"d":"0.02"},{"v":0.480021,"d":"0.48"},{"v":7.695164,"d":"7.70"},{"v":1.10029,"d":"1.10"},{"v":6.672215,"d":"6.67"},{"v":0.0621251333992213,"d":"0.06"},{"v":-4.00867914524566,"d":"-4.01"},{"v":0.00323082315577634,"d":"0.00"},{"v":0.166512186499679,"d":"0.17"},"down","yes"]
[50086,0,"chr12","-",132840352,132847802,"ENST00000545046",4,2186,"ENSG00000072609","CHFR","GO:0000166(nucleotide binding);GO:0000209(protein polyubiquitination);GO:0000278(mitotic cell cycle);GO:0004842(ubiquitin-protein transferase activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0006511(ubiquitin-dependent protein catabolic process);GO:0007049(cell cycle);GO:0007093(mitotic cell cycle checkpoint);GO:0016567(protein ubiquitination);GO:0016605(PML body);GO:0016740(transferase activity);GO:0019941(modification-dependent protein catabolic process);GO:0031398(positive regulation of protein ubiquitination);GO:0031648(protein destabilization);GO:0032436(positive regulation of proteasomal ubiquitin-dependent protein catabolic process);GO:0046872(metal ion binding);GO:0051301(cell division);GO:0061630(ubiquitin protein ligase activity)","NA","K10644","EC:2.3.2.27","checkpoint with forkhead and ring finger domains [Source:HGNC Symbol;Acc:HGNC:20455]",{"v":0.041966,"d":"0.04"},{"v":0.030491,"d":"0.03"},{"v":0.089265,"d":"0.09"},{"v":1.298798,"d":"1.30"},{"v":0.051174,"d":"0.05"},{"v":1.425573,"d":"1.43"},{"v":0.0582667548175223,"d":"0.06"},{"v":-4.10118322813775,"d":"-4.10"},{"v":0.00323124391638519,"d":"0.00"},{"v":0.166512186499679,"d":"0.17"},"down","yes"]
[80000,0,"chr17","-",3811523,3825021,"ENST00000574911",8,2701,"ENSG00000074356","NCBP3","GO:0000339(RNA cap binding);GO:0000340(RNA 7-methylguanosine cap binding);GO:0003723(RNA binding);GO:0003729(mRNA binding);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0006370(7-methylguanosine mRNA capping);GO:0006397(mRNA processing);GO:0016607(nuclear speck);GO:0034518(RNA cap binding complex);GO:0051028(mRNA transport);GO:0051607(defense response to virus)","NA","NA","NA","nuclear cap binding subunit 3 [Source:HGNC Symbol;Acc:HGNC:24612]",0,0,{"v":0.017392,"d":"0.02"},{"v":0.170865,"d":"0.17"},{"v":0.333479,"d":"0.33"},{"v":0.414634,"d":"0.41"},{"v":0.0189253714452359,"d":"0.02"},{"v":-5.72353457374121,"d":"-5.72"},{"v":0.00324911501892508,"d":"0.00"},{"v":0.167195961242986,"d":"0.17"},"down","yes"]
[170160,0,"chr6","+",36130484,36144524,"ENST00000373766",10,6196,"ENSG00000156711","MAPK13","GO:0000165(MAPK cascade);GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0004707(MAP kinase activity);GO:0005515(protein binding);GO:0005524(ATP binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0006468(protein phosphorylation);GO:0006970(response to osmotic stress);GO:0007049(cell cycle);GO:0010468(regulation of gene expression);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0016740(transferase activity);GO:0018105(peptidyl-serine phosphorylation);GO:0032755(positive regulation of interleukin-6 production);GO:0034644(cellular response to UV);GO:0035556(intracellular signal transduction);GO:0050729(positive regulation of inflammatory response);GO:0051403(stress-activated MAPK cascade);GO:0070301(cellular response to hydrogen peroxide);GO:0071310(cellular response to organic substance);GO:0071347(cellular response to interleukin-1);GO:0072709(cellular response to sorbitol);GO:0072740(cellular response to anisomycin);GO:1903936(cellular response to sodium arsenite)","01522(Endocrine resistance);04010(MAPK signaling pathway);04015(Rap1 signaling pathway);04068(FoxO signaling pathway);04071(Sphingolipid signaling pathway);04218(Cellular senescence);04261(Adrenergic signaling in cardiomyocytes);04370(VEGF signaling pathway);04380(Osteoclast differentiation);04550(Signaling pathways regulating pluripotency of stem cells);04611(Platelet activation);04620(Toll-like receptor signaling pathway);04621(NOD-like receptor signaling pathway);04622(RIG-I-like receptor signaling pathway);04625(C-type lectin receptor signaling pathway);04657(IL-17 signaling pathway);04658(Th1 and Th2 cell differentiation);04659(Th17 cell differentiation);04660(T cell receptor signaling pathway);04664(Fc epsilon RI signaling pathway);04668(TNF signaling pathway);04670(Leukocyte transendothelial migration);04714(Thermogenesis);04722(Neurotrophin signaling pathway);04723(Retrograde endocannabinoid signaling);04728(Dopaminergic synapse);04750(Inflammatory mediator regulation of TRP channels);04912(GnRH signaling pathway);04914(Progesterone-mediated oocyte maturation);04917(Prolactin signaling pathway);04926(Relaxin signaling pathway);04933(AGE-RAGE signaling pathway in diabetic complications);05014(Amyotrophic lateral sclerosis (ALS));05120(Epithelial cell signaling in Helicobacter pylori infection);05131(Shigellosis);05132(Salmonella infection);05133(Pertussis);05140(Leishmaniasis);05142(Chagas disease (American trypanosomiasis));05145(Toxoplasmosis);05152(Tuberculosis);05161(Hepatitis B);05163(Human cytomegalovirus infection);05164(Influenza A);05167(Kaposi sarcoma-associated herpesvirus infection);05169(Epstein-Barr virus infection);05170(Human immunodeficiency virus 1 infection);05205(Proteoglycans in cancer);05418(Fluid shear stress and atherosclerosis)","NA","NA","mitogen-activated protein kinase 13 [Source:HGNC Symbol;Acc:HGNC:6875]",0,{"v":0.012587,"d":"0.01"},0,{"v":0.020579,"d":"0.02"},{"v":0.30942,"d":"0.31"},{"v":0.359315,"d":"0.36"},{"v":0.0182601833126848,"d":"0.02"},{"v":-5.77515494126673,"d":"-5.78"},{"v":0.00327970207219667,"d":"0.00"},{"v":0.168531225294066,"d":"0.17"},"down","yes"]
[188522,0,"chr8","+",38787236,38853028,"ENST00000317827",13,7770,"ENSG00000147526","TACC1","GO:0000226(microtubule cytoskeleton organization);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005815(microtubule organizing center);GO:0005856(cytoskeleton);GO:0007049(cell cycle);GO:0007052(mitotic spindle organization);GO:0008283(cell population proliferation);GO:0016020(membrane);GO:0021987(cerebral cortex development);GO:0030496(midbody);GO:0051301(cell division)","NA","K14281","NA","transforming acidic coiled-coil containing protein 1 [Source:HGNC Symbol;Acc:HGNC:11522]",{"v":0.660893,"d":"0.66"},{"v":0.874108,"d":"0.87"},{"v":0.965603,"d":"0.97"},{"v":14.630423,"d":"14.63"},{"v":1.471022,"d":"1.47"},{"v":1.672029,"d":"1.67"},{"v":0.140693035025117,"d":"0.14"},{"v":-2.8293771848164,"d":"-2.83"},{"v":0.00330086412631761,"d":"0.00"},{"v":0.169379087159772,"d":"0.17"},"down","yes"]
[72973,0,"chr16","+",27313974,27364778,"ENST00000395762",11,3624,"ENSG00000077238","IL4R","GO:0002376(immune system process);GO:0002532(production of molecular mediator involved in inflammatory response);GO:0002639(positive regulation of immunoglobulin production);GO:0004896(cytokine receptor activity);GO:0004913(interleukin-4 receptor activity);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0005615(extracellular space);GO:0005886(plasma membrane);GO:0005887(integral component of plasma membrane);GO:0006955(immune response);GO:0007165(signal transduction);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016064(immunoglobulin mediated immune response);GO:0019221(cytokine-mediated signaling pathway);GO:0030728(ovulation);GO:0035771(interleukin-4-mediated signaling pathway);GO:0042127(regulation of cell population proliferation);GO:0042832(defense response to protozoan);GO:0043032(positive regulation of macrophage activation);GO:0043235(receptor complex);GO:0043306(positive regulation of mast cell degranulation);GO:0043627(response to estrogen);GO:0045626(negative regulation of T-helper 1 cell differentiation);GO:0045630(positive regulation of T-helper 2 cell differentiation);GO:0090197(positive regulation of chemokine secretion);GO:0120162(positive regulation of cold-induced thermogenesis);GO:1901741(positive regulation of myoblast fusion);GO:1990834(response to odorant)","04060(Cytokine-cytokine receptor interaction);04151(PI3K-Akt signaling pathway);04630(Jak-STAT signaling pathway);04640(Hematopoietic cell lineage);04658(Th1 and Th2 cell differentiation);04659(Th17 cell differentiation);05200(Pathways in cancer);05321(Inflammatory bowel disease (IBD))","K05071","NA","interleukin 4 receptor [Source:HGNC Symbol;Acc:HGNC:6015]",{"v":0.481321,"d":"0.48"},{"v":0.476315,"d":"0.48"},{"v":0.90692,"d":"0.91"},{"v":1.933357,"d":"1.93"},{"v":8.541439,"d":"8.54"},{"v":3.371772,"d":"3.37"},{"v":0.134658349996909,"d":"0.13"},{"v":-2.89262440254774,"d":"-2.89"},{"v":0.00333048994191056,"d":"0.00"},{"v":0.170658250478999,"d":"0.17"},"down","yes"]
[136328,0,"chr3","+",5122292,5180911,"ENST00000256496",7,2933,"ENSG00000134108","ARL8B","GO:0000166(nucleotide binding);GO:0003924(GTPase activity);GO:0005515(protein binding);GO:0005525(GTP binding);GO:0005737(cytoplasm);GO:0005764(lysosome);GO:0005765(lysosomal membrane);GO:0005768(endosome);GO:0005774(vacuolar membrane);GO:0005819(spindle);GO:0005856(cytoskeleton);GO:0007049(cell cycle);GO:0007059(chromosome segregation);GO:0008089(anterograde axonal transport);GO:0015031(protein transport);GO:0016020(membrane);GO:0019003(GDP binding);GO:0030054(cell junction);GO:0030424(axon);GO:0030496(midbody);GO:0031902(late endosome membrane);GO:0032418(lysosome localization);GO:0042995(cell projection);GO:0043014(alpha-tubulin binding);GO:0045202(synapse);GO:0048487(beta-tubulin binding);GO:0051233(spindle midzone);GO:0051301(cell division);GO:0070062(extracellular exosome);GO:1904115(axon cytoplasm)","NA","K07955","NA","ADP ribosylation factor like GTPase 8B [Source:HGNC Symbol;Acc:HGNC:25564]",{"v":1.204434,"d":"1.20"},{"v":1.121823,"d":"1.12"},{"v":0.934123,"d":"0.93"},{"v":0.741386,"d":"0.74"},{"v":38.425705,"d":"38.43"},{"v":1.50294,"d":"1.50"},{"v":0.0801666465412824,"d":"0.08"},{"v":-3.6408540637936,"d":"-3.64"},{"v":0.00335603860604058,"d":"0.00"},{"v":0.17172518670064,"d":"0.17"},"down","yes"]
[13756,0,"chr1","+",167936661,168075843,"ENST00000367843",20,3302,"ENSG00000143164","DCAF6","GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0005925(focal adhesion);GO:0016567(protein ubiquitination);GO:0030374(nuclear receptor transcription coactivator activity);GO:0043687(post-translational protein modification);GO:0045944(positive regulation of transcription by RNA polymerase II);GO:0080008(Cul4-RING E3 ubiquitin ligase complex)","NA","K11795","NA","DDB1 and CUL4 associated factor 6 [Source:HGNC Symbol;Acc:HGNC:30002]",{"v":0.320468,"d":"0.32"},{"v":0.136007,"d":"0.14"},{"v":0.263574,"d":"0.26"},{"v":1.755508,"d":"1.76"},{"v":1.047196,"d":"1.05"},{"v":3.842017,"d":"3.84"},{"v":0.108364068258095,"d":"0.11"},{"v":-3.20604163283867,"d":"-3.21"},{"v":0.00336753560151488,"d":"0.00"},{"v":0.171944810130765,"d":"0.17"},"down","yes"]
[90472,0,"chr17","-",75845720,75856507,"ENST00000591399",9,2225,"ENSG00000132471","WBP2","GO:0000790(nuclear chromatin);GO:0000978(RNA polymerase II proximal promoter sequence-specific DNA binding);GO:0003713(transcription coactivator activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0030331(estrogen receptor binding);GO:0031490(chromatin DNA binding);GO:0032570(response to progesterone);GO:0033148(positive regulation of intracellular estrogen receptor signaling pathway);GO:0043627(response to estrogen);GO:0045184(establishment of protein localization);GO:0045815(positive regulation of gene expression, epigenetic);GO:0045944(positive regulation of transcription by RNA polymerase II);GO:0050847(progesterone receptor signaling pathway);GO:0071391(cellular response to estrogen stimulus);GO:0071442(positive regulation of histone H3-K14 acetylation);GO:1903508(positive regulation of nucleic acid-templated transcription)","NA","K22524","NA","WW domain binding protein 2 [Source:HGNC Symbol;Acc:HGNC:12738]",{"v":0.24939,"d":"0.25"},{"v":0.055495,"d":"0.06"},{"v":0.001261,"d":"0.00"},{"v":1.52326,"d":"1.52"},{"v":0.66464,"d":"0.66"},{"v":3.464698,"d":"3.46"},{"v":0.0541602286240769,"d":"0.05"},{"v":-4.20662236086688,"d":"-4.21"},{"v":0.0033710964982713,"d":"0.00"},{"v":0.171944810130765,"d":"0.17"},"down","yes"]
[36687,0,"chr11","-",117208673,117218464,"ENST00000528973",2,9347,"ENSG00000160613","PCSK7","GO:0004252(serine-type endopeptidase activity);GO:0005794(Golgi apparatus);GO:0005802(trans-Golgi network);GO:0006508(proteolysis);GO:0008233(peptidase activity);GO:0008236(serine-type peptidase activity);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016485(protein processing);GO:0016486(peptide hormone processing);GO:0016787(hydrolase activity);GO:0030173(integral component of Golgi membrane)","NA","K08673","EC:3.4.21.-","proprotein convertase subtilisin/kexin type 7 [Source:HGNC Symbol;Acc:HGNC:8748]",{"v":5e-6,"d":"0.00"},0,0,{"v":0.103213,"d":"0.10"},{"v":0.13025,"d":"0.13"},0,{"v":2.14166698791672e-5,"d":"0.00"},{"v":-15.5109063044472,"d":"-15.51"},{"v":0.0033754758255816,"d":"0.00"},{"v":0.171944810130765,"d":"0.17"},"down","yes"]
[43077,0,"chr12","+",51951744,51987346,"ENST00000415850",7,1665,"ENSG00000135503","ACVR1B","GO:0000082(G1/S transition of mitotic cell cycle);GO:0000166(nucleotide binding);GO:0001701(in utero embryonic development);GO:0001942(hair follicle development);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0004675(transmembrane receptor protein serine/threonine kinase activity);GO:0005024(transforming growth factor beta-activated receptor activity);GO:0005025(transforming growth factor beta receptor activity, type I);GO:0005515(protein binding);GO:0005524(ATP binding);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0005887(integral component of plasma membrane);GO:0006355(regulation of transcription, DNA-templated);GO:0006468(protein phosphorylation);GO:0007165(signal transduction);GO:0007178(transmembrane receptor protein serine/threonine kinase signaling pathway);GO:0007179(transforming growth factor beta receptor signaling pathway);GO:0007389(pattern specification process);GO:0007417(central nervous system development);GO:0009966(regulation of signal transduction);GO:0009986(cell surface);GO:0010628(positive regulation of gene expression);GO:0010629(negative regulation of gene expression);GO:0010862(positive regulation of pathway-restricted SMAD protein phosphorylation);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0016361(activin receptor activity, type I);GO:0016740(transferase activity);GO:0017002(activin-activated receptor activity);GO:0018107(peptidyl-threonine phosphorylation);GO:0019838(growth factor binding);GO:0030308(negative regulation of cell growth);GO:0031625(ubiquitin protein ligase binding);GO:0032924(activin receptor signaling pathway);GO:0032927(positive regulation of activin receptor signaling pathway);GO:0034711(inhibin binding);GO:0038092(nodal signaling pathway);GO:0043235(receptor complex);GO:0045648(positive regulation of erythrocyte differentiation);GO:0045944(positive regulation of transcription by RNA polymerase II);GO:0046332(SMAD binding);GO:0046545(development of primary female sexual characteristics);GO:0046777(protein autophosphorylation);GO:0046872(metal ion binding);GO:0048179(activin receptor complex);GO:0048185(activin binding);GO:0097191(extrinsic apoptotic signaling pathway);GO:1901165(positive regulation of trophoblast cell migration)","04060(Cytokine-cytokine receptor interaction);04350(TGF-beta signaling pathway);04550(Signaling pathways regulating pluripotency of stem cells)","NA","NA","activin A receptor type 1B [Source:HGNC Symbol;Acc:HGNC:172]",{"v":0.109281,"d":"0.11"},{"v":0.123114,"d":"0.12"},{"v":0.143623,"d":"0.14"},{"v":0.228464,"d":"0.23"},{"v":1.991105,"d":"1.99"},{"v":2.150063,"d":"2.15"},{"v":0.0860525554554709,"d":"0.09"},{"v":-3.53863815395093,"d":"-3.54"},{"v":0.00337926216441965,"d":"0.00"},{"v":0.171944810130765,"d":"0.17"},"down","yes"]
[140950,0,"chr3","+",53846568,53865794,"ENST00000288167",11,2016,"ENSG00000056736","IL17RB","GO:0001558(regulation of cell growth);GO:0004896(cytokine receptor activity);GO:0005576(extracellular region);GO:0005737(cytoplasm);GO:0005886(plasma membrane);GO:0005887(integral component of plasma membrane);GO:0006952(defense response);GO:0009986(cell surface);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0019221(cytokine-mediated signaling pathway);GO:0030368(interleukin-17 receptor activity);GO:0050729(positive regulation of inflammatory response);GO:0097400(interleukin-17-mediated signaling pathway);GO:2000664(positive regulation of interleukin-5 secretion);GO:2000667(positive regulation of interleukin-13 secretion)","04060(Cytokine-cytokine receptor interaction);04657(IL-17 signaling pathway)","K05165","NA","interleukin 17 receptor B [Source:HGNC Symbol;Acc:HGNC:18015]",{"v":0.014702,"d":"0.01"},0,0,{"v":1.11553,"d":"1.12"},{"v":1.112735,"d":"1.11"},0,{"v":0.00659795850134522,"d":"0.01"},{"v":-7.24376458073495,"d":"-7.24"},{"v":0.00342287566141148,"d":"0.00"},{"v":0.173920381509201,"d":"0.17"},"down","yes"]
[134382,0,"chr22","+",37608834,37633564,"ENST00000343632",17,2800,"ENSG00000100083","GGA1","GO:0003674(molecular_function);GO:0005515(protein binding);GO:0005622(intracellular);GO:0005623(cell);GO:0005654(nucleoplasm);GO:0005768(endosome);GO:0005769(early endosome);GO:0005794(Golgi apparatus);GO:0005829(cytosol);GO:0006886(intracellular protein transport);GO:0006893(Golgi to plasma membrane transport);GO:0008104(protein localization);GO:0010008(endosome membrane);GO:0015031(protein transport);GO:0016020(membrane);GO:0016192(vesicle-mediated transport);GO:0030306(ADP-ribosylation factor binding);GO:0031901(early endosome membrane);GO:0032991(protein-containing complex);GO:0034394(protein localization to cell surface);GO:0042147(retrograde transport, endosome to Golgi);GO:0043001(Golgi to plasma membrane protein transport);GO:0043231(intracellular membrane-bounded organelle);GO:0044267(cellular protein metabolic process);GO:0045732(positive regulation of protein catabolic process);GO:0046982(protein heterodimerization activity);GO:1901998(toxin transport);GO:1903441(protein localization to ciliary membrane)","04142(Lysosome)","K12404","NA","golgi associated, gamma adaptin ear containing, ARF binding protein 1 [Source:HGNC Symbol;Acc:HGNC:17842]",{"v":0.112104,"d":"0.11"},{"v":0.033998,"d":"0.03"},{"v":0.049372,"d":"0.05"},{"v":0.130536,"d":"0.13"},{"v":2.591825,"d":"2.59"},{"v":0.417704,"d":"0.42"},{"v":0.0622515775947313,"d":"0.06"},{"v":-4.00574579099954,"d":"-4.01"},{"v":0.00346099285943887,"d":"0.00"},{"v":0.175611551094154,"d":"0.18"},"down","yes"]
[160449,0,"chr5","+",80408024,80479140,"ENST00000510158",19,6680,"ENSG00000039319","ZFYVE16","GO:0005515(protein binding);GO:0005545(1-phosphatidylinositol binding);GO:0005547(phosphatidylinositol-3,4,5-trisphosphate binding);GO:0005737(cytoplasm);GO:0005768(endosome);GO:0005769(early endosome);GO:0005829(cytosol);GO:0006622(protein targeting to lysosome);GO:0007165(signal transduction);GO:0008565(protein transporter activity);GO:0016020(membrane);GO:0016050(vesicle organization);GO:0016197(endosomal transport);GO:0030100(regulation of endocytosis);GO:0030509(BMP signaling pathway);GO:0031901(early endosome membrane);GO:0043231(intracellular membrane-bounded organelle);GO:0046872(metal ion binding)","04144(Endocytosis);04350(TGF-beta signaling pathway)","K04679","NA","zinc finger FYVE-type containing 16 [Source:HGNC Symbol;Acc:HGNC:20756]",{"v":0.0054,"d":"0.01"},{"v":0.124393,"d":"0.12"},{"v":0.002591,"d":"0.00"},{"v":0.836481,"d":"0.84"},{"v":1.060272,"d":"1.06"},{"v":0.529949,"d":"0.53"},{"v":0.054553051837432,"d":"0.05"},{"v":-4.19619628291287,"d":"-4.20"},{"v":0.0034675746497769,"d":"0.00"},{"v":0.175700121375725,"d":"0.18"},"down","yes"]
[130105,0,"chr21","-",34516484,34526963,"ENST00000381132",4,2408,"ENSG00000159200","RCAN1","GO:0002931(response to ischemia);GO:0003676(nucleic acid binding);GO:0003677(DNA binding);GO:0003700(DNA-binding transcription factor activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0006355(regulation of transcription, DNA-templated);GO:0006979(response to oxidative stress);GO:0007165(signal transduction);GO:0007417(central nervous system development);GO:0007519(skeletal muscle tissue development);GO:0007614(short-term memory);GO:0008015(blood circulation);GO:0008597(calcium-dependent protein serine/threonine phosphatase regulator activity);GO:0009612(response to mechanical stimulus);GO:0019722(calcium-mediated signaling);GO:0031987(locomotion involved in locomotory behavior);GO:0033173(calcineurin-NFAT signaling cascade);GO:0043627(response to estrogen);GO:0043666(regulation of phosphoprotein phosphatase activity);GO:0048741(skeletal muscle fiber development);GO:0051151(negative regulation of smooth muscle cell differentiation);GO:0070884(regulation of calcineurin-NFAT signaling cascade);GO:0070885(negative regulation of calcineurin-NFAT signaling cascade)","04919(Thyroid hormone signaling pathway);04921(Oxytocin signaling pathway);05167(Kaposi sarcoma-associated herpesvirus infection)","K17901","NA","regulator of calcineurin 1 [Source:HGNC Symbol;Acc:HGNC:3040]",{"v":65.769402,"d":"65.77"},{"v":131.924484,"d":"131.92"},{"v":86.208321,"d":"86.21"},{"v":27.504591,"d":"27.50"},{"v":10.597206,"d":"10.60"},{"v":28.891846,"d":"28.89"},{"v":4.23774845323757,"d":"4.24"},{"v":2.08329795391177,"d":"2.08"},{"v":0.00350361103605238,"d":"0.00"},{"v":0.177278814679363,"d":"0.18"},"up","yes"]
[24789,0,"chr10","+",119818727,119829147,"ENST00000650409",6,3693,"ENSG00000198825","INPP5F","GO:0001921(positive regulation of receptor recycling);GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0005768(endosome);GO:0005769(early endosome);GO:0005905(clathrin-coated pit);GO:0006661(phosphatidylinositol biosynthetic process);GO:0008344(adult locomotory behavior);GO:0008934(inositol monophosphate 1-phosphatase activity);GO:0014898(cardiac muscle hypertrophy in response to stress);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016787(hydrolase activity);GO:0030424(axon);GO:0030425(dendrite);GO:0031161(phosphatidylinositol catabolic process);GO:0031901(early endosome membrane);GO:0033137(negative regulation of peptidyl-serine phosphorylation);GO:0034595(phosphatidylinositol phosphate 5-phosphatase activity);GO:0034596(phosphatidylinositol phosphate 4-phosphatase activity);GO:0042532(negative regulation of tyrosine phosphorylation of STAT protein);GO:0042578(phosphoric ester hydrolase activity);GO:0042803(protein homodimerization activity);GO:0043025(neuronal cell body);GO:0043812(phosphatidylinositol-4-phosphate phosphatase activity);GO:0045334(clathrin-coated endocytic vesicle);GO:0046856(phosphatidylinositol dephosphorylation);GO:0048015(phosphatidylinositol-mediated signaling);GO:0048681(negative regulation of axon regeneration);GO:0051896(regulation of protein kinase B signaling);GO:0052832(inositol monophosphate 3-phosphatase activity);GO:0052833(inositol monophosphate 4-phosphatase activity);GO:0052834(inositol monophosphate phosphatase activity);GO:0055037(recycling endosome);GO:0070072(vacuolar proton-transporting V-type ATPase complex assembly);GO:0072583(clathrin-dependent endocytosis);GO:2000145(regulation of cell motility);GO:2001135(regulation of endocytic recycling)","00562(Inositol phosphate metabolism);04070(Phosphatidylinositol signaling system)","K21798","EC:3.1.3.-","inositol polyphosphate-5-phosphatase F [Source:HGNC Symbol;Acc:HGNC:17054]",{"v":4.934497,"d":"4.93"},{"v":1.223632,"d":"1.22"},{"v":5.042243,"d":"5.04"},{"v":0.283552,"d":"0.28"},{"v":0.187756,"d":"0.19"},{"v":0.771763,"d":"0.77"},{"v":9.01024317999535,"d":"9.01"},{"v":3.17156604386777,"d":"3.17"},{"v":0.00351329259571567,"d":"0.00"},{"v":0.177521446456676,"d":"0.18"},"up","yes"]
[160624,0,"chr5","-",83637805,83721613,"ENST00000274341",5,5607,"ENSG00000145681","HAPLN1","GO:0001501(skeletal system development);GO:0005540(hyaluronic acid binding);GO:0005576(extracellular region);GO:0007155(cell adhesion);GO:0007417(central nervous system development);GO:0030021(extracellular matrix structural constituent conferring compression resistance);GO:0030198(extracellular matrix organization);GO:0031012(extracellular matrix);GO:0045202(synapse);GO:0062023(collagen-containing extracellular matrix)","NA","NA","NA","hyaluronan and proteoglycan link protein 1 [Source:HGNC Symbol;Acc:HGNC:2380]",{"v":1.74921,"d":"1.75"},{"v":2.089652,"d":"2.09"},{"v":2.036433,"d":"2.04"},{"v":8.64304,"d":"8.64"},{"v":8.291425,"d":"8.29"},{"v":7.58391,"d":"7.58"},{"v":0.23962823800517,"d":"0.24"},{"v":-2.06113016827327,"d":"-2.06"},{"v":0.00352260427934242,"d":"0.00"},{"v":0.177683024224325,"d":"0.18"},"down","yes"]
[8409,0,"chr1","-",93887034,93909456,"ENST00000615724",6,3008,"ENSG00000023909","GCLM","GO:0004357(glutamate-cysteine ligase activity);GO:0005829(cytosol);GO:0006534(cysteine metabolic process);GO:0006536(glutamate metabolic process);GO:0006749(glutathione metabolic process);GO:0006750(glutathione biosynthetic process);GO:0006979(response to oxidative stress);GO:0007568(aging);GO:0007584(response to nutrient);GO:0008637(apoptotic mitochondrial changes);GO:0014823(response to activity);GO:0017109(glutamate-cysteine ligase complex);GO:0030234(enzyme regulator activity);GO:0035226(glutamate-cysteine ligase catalytic subunit binding);GO:0035229(positive regulation of glutamate-cysteine ligase activity);GO:0035729(cellular response to hepatocyte growth factor stimulus);GO:0035733(hepatic stellate cell activation);GO:0042493(response to drug);GO:0043524(negative regulation of neuron apoptotic process);GO:0044344(cellular response to fibroblast growth factor stimulus);GO:0044752(response to human chorionic gonadotropin);GO:0046982(protein heterodimerization activity);GO:0050880(regulation of blood vessel size);GO:0051409(response to nitrosative stress);GO:0051900(regulation of mitochondrial depolarization);GO:0071333(cellular response to glucose stimulus);GO:0071372(cellular response to follicle-stimulating hormone stimulus);GO:0097069(cellular response to thyroxine stimulus);GO:1990830(cellular response to leukemia inhibitory factor);GO:2001237(negative regulation of extrinsic apoptotic signaling pathway)","00270(Cysteine and methionine metabolism);00480(Glutathione metabolism);04216(Ferroptosis)","NA","NA","glutamate-cysteine ligase modifier subunit [Source:HGNC Symbol;Acc:HGNC:4312]",{"v":0.009758,"d":"0.01"},{"v":0.010047,"d":"0.01"},{"v":0.009572,"d":"0.01"},{"v":0.407217,"d":"0.41"},{"v":0.564699,"d":"0.56"},{"v":0.02259,"d":"0.02"},{"v":0.0295392888529582,"d":"0.03"},{"v":-5.08122109558334,"d":"-5.08"},{"v":0.00352627196437485,"d":"0.00"},{"v":0.177683024224325,"d":"0.18"},"down","yes"]
[147497,0,"chr3","+",184812143,185052614,"ENST00000287546",47,5047,"ENSG00000156931","VPS8","GO:0005515(protein binding);GO:0005768(endosome);GO:0005769(early endosome);GO:0015031(protein transport);GO:0033263(CORVET complex);GO:0034058(endosomal vesicle fusion);GO:0046872(metal ion binding)","NA","K20178","NA","VPS8, CORVET complex subunit [Source:HGNC Symbol;Acc:HGNC:29122]",{"v":0.000704,"d":"0.00"},{"v":0.010156,"d":"0.01"},{"v":0.014737,"d":"0.01"},{"v":0.236671,"d":"0.24"},{"v":0.606271,"d":"0.61"},{"v":0.014359,"d":"0.01"},{"v":0.0298576579287788,"d":"0.03"},{"v":-5.06575518662829,"d":"-5.07"},{"v":0.00355081219710243,"d":"0.00"},{"v":0.178452524366825,"d":"0.18"},"down","yes"]
[135272,0,"chr22","-",42585887,42603012,"ENST00000491021",9,1028,"ENSG00000100227","POLDIP3","GO:0000346(transcription export complex);GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0005515(protein binding);GO:0005623(cell);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0006405(RNA export from nucleus);GO:0006406(mRNA export from nucleus);GO:0006417(regulation of translation);GO:0016607(nuclear speck);GO:0016973(poly(A)+ mRNA export from nucleus);GO:0031124(mRNA 3'-end processing);GO:0036464(cytoplasmic ribonucleoprotein granule);GO:0044877(protein-containing complex binding);GO:0045727(positive regulation of translation);GO:0051028(mRNA transport)","NA","K22414","NA","DNA polymerase delta interacting protein 3 [Source:HGNC Symbol;Acc:HGNC:23782]",{"v":0.109406,"d":"0.11"},{"v":0.046606,"d":"0.05"},{"v":0.050903,"d":"0.05"},{"v":2.986722,"d":"2.99"},{"v":2.447869,"d":"2.45"},{"v":0.023622,"d":"0.02"},{"v":0.0379089273357416,"d":"0.04"},{"v":-4.72131855493064,"d":"-4.72"},{"v":0.00355136733050411,"d":"0.00"},{"v":0.178452524366825,"d":"0.18"},"down","yes"]
[123200,0,"chr2","+",232633604,232682776,"ENST00000264059",4,1878,"ENSG00000115468","EFHD1","GO:0005509(calcium ion binding);GO:0005739(mitochondrion);GO:0005743(mitochondrial inner membrane);GO:0016020(membrane);GO:0031175(neuron projection development);GO:0046872(metal ion binding);GO:0061891(calcium ion sensor activity);GO:1900069(regulation of cellular hyperosmotic salinity response)","NA","NA","NA","EF-hand domain family member D1 [Source:HGNC Symbol;Acc:HGNC:29556]",{"v":0.406937,"d":"0.41"},{"v":1.328149,"d":"1.33"},{"v":1.381988,"d":"1.38"},{"v":5.258117,"d":"5.26"},{"v":9.215742,"d":"9.22"},{"v":8.160724,"d":"8.16"},{"v":0.137712897118538,"d":"0.14"},{"v":-2.86026441749398,"d":"-2.86"},{"v":0.00356803077817204,"d":"0.00"},{"v":0.179042207418495,"d":"0.18"},"down","yes"]
[192631,0,"chr8","+",127736069,127742950,"ENST00000621592",3,3882,"ENSG00000136997","MYC","GO:0000082(G1/S transition of mitotic cell cycle);GO:0000122(negative regulation of transcription by RNA polymerase II);GO:0000165(MAPK cascade);GO:0000320(re-entry into mitotic cell cycle);GO:0000790(nuclear chromatin);GO:0000978(RNA polymerase II proximal promoter sequence-specific DNA binding);GO:0000981(DNA-binding transcription factor activity, RNA polymerase II-specific);GO:0001227(DNA-binding transcription repressor activity, RNA polymerase II-specific);GO:0001228(DNA-binding transcription activator activity, RNA polymerase II-specific);GO:0001541(ovarian follicle development);GO:0001658(branching involved in ureteric bud morphogenesis);GO:0001701(in utero embryonic development);GO:0002053(positive regulation of mesenchymal cell proliferation);GO:0002082(regulation of oxidative phosphorylation);GO:0003677(DNA binding);GO:0003690(double-stranded DNA binding);GO:0003700(DNA-binding transcription factor activity);GO:0003729(mRNA binding);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005635(nuclear envelope);GO:0005654(nucleoplasm);GO:0005730(nucleolus);GO:0005737(cytoplasm);GO:0005791(rough endoplasmic reticulum);GO:0006006(glucose metabolic process);GO:0006112(energy reserve metabolic process);GO:0006338(chromatin remodeling);GO:0006351(transcription, DNA-templated);GO:0006352(DNA-templated transcription, initiation);GO:0006355(regulation of transcription, DNA-templated);GO:0006357(regulation of transcription by RNA polymerase II);GO:0006366(transcription by RNA polymerase II);GO:0006848(pyruvate transport);GO:0006865(amino acid transport);GO:0006879(cellular iron ion homeostasis);GO:0006974(cellular response to DNA damage stimulus);GO:0007007(inner mitochondrial membrane organization);GO:0007050(cell cycle arrest);GO:0007219(Notch signaling pathway);GO:0007346(regulation of mitotic cell cycle);GO:0008134(transcription factor binding);GO:0008150(biological_process);GO:0008283(cell population proliferation);GO:0008284(positive regulation of cell population proliferation);GO:0009611(response to wounding);GO:0009812(flavonoid metabolic process);GO:0010332(response to gamma radiation);GO:0010468(regulation of gene expression);GO:0010628(positive regulation of gene expression);GO:0010629(negative regulation of gene expression);GO:0010918(positive regulation of mitochondrial membrane potential);GO:0014911(positive regulation of smooth muscle cell migration);GO:0015671(oxygen transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016579(protein deubiquitination);GO:0019087(transformation of host cell by virus);GO:0019221(cytokine-mediated signaling pathway);GO:0021854(hypothalamus development);GO:0030728(ovulation);GO:0032204(regulation of telomere maintenance);GO:0032355(response to estradiol);GO:0032869(cellular response to insulin stimulus);GO:0032873(negative regulation of stress-activated MAPK cascade);GO:0032986(protein-DNA complex disassembly);GO:0032991(protein-containing complex);GO:0033613(activating transcription factor binding);GO:0034644(cellular response to UV);GO:0035690(cellular response to drug);GO:0036120(cellular response to platelet-derived growth factor stimulus);GO:0042493(response to drug);GO:0043066(negative regulation of apoptotic process);GO:0043280(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process);GO:0043388(positive regulation of DNA binding);GO:0043565(sequence-specific DNA binding);GO:0044195(nucleoplasmic reticulum);GO:0044344(cellular response to fibroblast growth factor stimulus);GO:0044346(fibroblast apoptotic process);GO:0044752(response to human chorionic gonadotropin);GO:0044877(protein-containing complex binding);GO:0045023(G0 to G1 transition);GO:0045471(response to ethanol);GO:0045656(negative regulation of monocyte differentiation);GO:0045727(positive regulation of translation);GO:0045787(positive regulation of cell cycle);GO:0045821(positive regulation of glycolytic process);GO:0045893(positive regulation of transcription, DNA-templated);GO:0045944(positive regulation of transcription by RNA polymerase II);GO:0046325(negative regulation of glucose import);GO:0046722(lactic acid secretion);GO:0046982(protein heterodimerization activity);GO:0046983(protein dimerization activity);GO:0048146(positive regulation of fibroblast proliferation);GO:0048147(negative regulation of fibroblast proliferation);GO:0048661(positive regulation of smooth muscle cell proliferation);GO:0050679(positive regulation of epithelial cell proliferation);GO:0051276(chromosome organization);GO:0051782(negative regulation of cell division);GO:0051973(positive regulation of telomerase activity);GO:0060252(positive regulation of glial cell proliferation);GO:0060548(negative regulation of cell death);GO:0070371(ERK1 and ERK2 cascade);GO:0070491(repressing transcription factor binding);GO:0070848(response to growth factor);GO:0070888(E-box binding);GO:0071074(eukaryotic initiation factor eIF2 binding);GO:0071300(cellular response to retinoic acid);GO:0071322(cellular response to carbohydrate stimulus);GO:0071346(cellular response to interferon-gamma);GO:0071347(cellular response to interleukin-1);GO:0071364(cellular response to epidermal growth factor stimulus);GO:0071378(cellular response to growth hormone stimulus);GO:0071391(cellular response to estrogen stimulus);GO:0071394(cellular response to testosterone stimulus);GO:0071407(cellular response to organic cyclic compound);GO:0071409(cellular response to cycloheximide);GO:0071456(cellular response to hypoxia);GO:0071464(cellular response to hydrostatic pressure);GO:0071966(fungal-type cell wall polysaccharide metabolic process);GO:0090096(positive regulation of metanephric cap mesenchymal cell proliferation);GO:0097421(liver regeneration);GO:1901857(positive regulation of cellular respiration);GO:1903841(cellular response to arsenite(3-));GO:1903862(positive regulation of oxidative phosphorylation);GO:1904385(cellular response to angiotensin);GO:1904586(cellular response to putrescine);GO:1904620(cellular response to dimethyl sulfoxide);GO:1904628(cellular response to phorbol 13-acetate 12-myristate);GO:1904837(beta-catenin-TCF complex assembly);GO:1905643(positive regulation of DNA methylation);GO:1990646(cellular response to prolactin);GO:1990858(cellular response to lectin);GO:1990859(cellular response to endothelin);GO:2000573(positive regulation of DNA biosynthetic process);GO:2001022(positive regulation of response to DNA damage stimulus);GO:2001171(positive regulation of ATP biosynthetic process)","04010(MAPK signaling pathway);04012(ErbB signaling pathway);04110(Cell cycle);04151(PI3K-Akt signaling pathway);04218(Cellular senescence);04310(Wnt signaling pathway);04350(TGF-beta signaling pathway);04390(Hippo signaling pathway);04550(Signaling pathways regulating pluripotency of stem cells);04630(Jak-STAT signaling pathway);04919(Thyroid hormone signaling pathway);05160(Hepatitis C);05161(Hepatitis B);05163(Human cytomegalovirus infection);05166(Human T-cell leukemia virus 1 infection);05167(Kaposi sarcoma-associated herpesvirus infection);05169(Epstein-Barr virus infection);05200(Pathways in cancer);05202(Transcriptional misregulation in cancer);05205(Proteoglycans in cancer);05206(MicroRNAs in cancer);05210(Colorectal cancer);05213(Endometrial cancer);05216(Thyroid cancer);05219(Bladder cancer);05220(Chronic myeloid leukemia);05221(Acute myeloid leukemia);05222(Small cell lung cancer);05224(Breast cancer);05225(Hepatocellular carcinoma);05226(Gastric cancer);05230(Central carbon metabolism in cancer)","K04377","NA","MYC proto-oncogene, bHLH transcription factor [Source:HGNC Symbol;Acc:HGNC:7553]",{"v":0.205905,"d":"0.21"},{"v":0.143368,"d":"0.14"},{"v":0.188292,"d":"0.19"},{"v":1.939608,"d":"1.94"},{"v":3.66773,"d":"3.67"},{"v":0.262002,"d":"0.26"},{"v":0.0915886624390476,"d":"0.09"},{"v":-3.44868716847539,"d":"-3.45"},{"v":0.00363514002847884,"d":"0.00"},{"v":0.182158120323636,"d":"0.18"},"down","yes"]
[37579,0,"chr11","-",123723914,123741660,"ENST00000530393",9,4435,"ENSG00000166261","ZNF202","GO:0000122(negative regulation of transcription by RNA polymerase II);GO:0000978(RNA polymerase II proximal promoter sequence-specific DNA binding);GO:0000981(DNA-binding transcription factor activity, RNA polymerase II-specific);GO:0001227(DNA-binding transcription repressor activity, RNA polymerase II-specific);GO:0003676(nucleic acid binding);GO:0003677(DNA binding);GO:0003700(DNA-binding transcription factor activity);GO:0005515(protein binding);GO:0005622(intracellular);GO:0005634(nucleus);GO:0006355(regulation of transcription, DNA-templated);GO:0006366(transcription by RNA polymerase II);GO:0006629(lipid metabolic process);GO:0046872(metal ion binding)","NA","K09229","NA","zinc finger protein 202 [Source:HGNC Symbol;Acc:HGNC:12994]",{"v":0.021886,"d":"0.02"},{"v":2.33321,"d":"2.33"},{"v":2.527765,"d":"2.53"},{"v":0.056222,"d":"0.06"},{"v":0.115481,"d":"0.12"},{"v":0.086051,"d":"0.09"},{"v":18.9438805993311,"d":"18.94"},{"v":4.24365998788749,"d":"4.24"},{"v":0.00364594296556943,"d":"0.00"},{"v":0.182447807078702,"d":"0.18"},"up","yes"]
[57098,0,"chr14","-",58408874,58412113,"ENST00000555061",3,598,"ENSG00000100575","TIMM9","GO:0005215(transporter activity);GO:0005515(protein binding);GO:0005739(mitochondrion);GO:0005743(mitochondrial inner membrane);GO:0005758(mitochondrial intermembrane space);GO:0006626(protein targeting to mitochondrion);GO:0007605(sensory perception of sound);GO:0008270(zinc ion binding);GO:0015031(protein transport);GO:0016020(membrane);GO:0042719(mitochondrial intermembrane space protein transporter complex);GO:0042803(protein homodimerization activity);GO:0045039(protein insertion into mitochondrial inner membrane);GO:0046872(metal ion binding);GO:0051087(chaperone binding);GO:0072321(chaperone-mediated protein transport)","NA","K17777","NA","translocase of inner mitochondrial membrane 9 [Source:HGNC Symbol;Acc:HGNC:11819]",{"v":0.053935,"d":"0.05"},{"v":0.097344,"d":"0.10"},{"v":0.063699,"d":"0.06"},{"v":3.625534,"d":"3.63"},{"v":1.580948,"d":"1.58"},{"v":0.247217,"d":"0.25"},{"v":0.0394187504664266,"d":"0.04"},{"v":-4.66497414460746,"d":"-4.66"},{"v":0.00366828376897459,"d":"0.00"},{"v":0.183313272801715,"d":"0.18"},"down","yes"]
[37617,0,"chr11","+",124115362,124147721,"ENST00000456829",19,4388,"ENSG00000110002","VWA5A","GO:0005634(nucleus);GO:0005654(nucleoplasm)","NA","NA","NA","von Willebrand factor A domain containing 5A [Source:HGNC Symbol;Acc:HGNC:6658]",{"v":0.327398,"d":"0.33"},{"v":13.341984,"d":"13.34"},{"v":0.471664,"d":"0.47"},{"v":0.226818,"d":"0.23"},{"v":0.31418,"d":"0.31"},{"v":0.400813,"d":"0.40"},{"v":15.0147386259027,"d":"15.01"},{"v":3.90830745580333,"d":"3.91"},{"v":0.00374898023060763,"d":"0.00"},{"v":0.187088532662054,"d":"0.19"},"up","yes"]
[51895,0,"chr13","+",50909747,50973745,"ENST00000422660",10,4885,"ENSG00000136104","RNASEH2B","GO:0001701(in utero embryonic development);GO:0004523(RNA-DNA hybrid ribonuclease activity);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0006401(RNA catabolic process);GO:0009259(ribonucleotide metabolic process);GO:0010389(regulation of G2/M transition of mitotic cell cycle);GO:0010629(negative regulation of gene expression);GO:0032299(ribonuclease H2 complex);GO:0048146(positive regulation of fibroblast proliferation);GO:0090502(RNA phosphodiester bond hydrolysis, endonucleolytic);GO:2000001(regulation of DNA damage checkpoint)","03030(DNA replication)","K10744","NA","ribonuclease H2 subunit B [Source:HGNC Symbol;Acc:HGNC:25671]",{"v":0.043872,"d":"0.04"},{"v":0.030183,"d":"0.03"},{"v":0.003629,"d":"0.00"},{"v":0.351545,"d":"0.35"},{"v":0.054585,"d":"0.05"},{"v":0.868935,"d":"0.87"},{"v":0.0609255214440048,"d":"0.06"},{"v":-4.03680949616159,"d":"-4.04"},{"v":0.00377344540462484,"d":"0.00"},{"v":0.18805112695476,"d":"0.19"},"down","yes"]
[33026,0,"chr11","-",67351565,67353490,"ENST00000528087",2,1701,"ENSG00000175482","POLD4","GO:0000723(telomere maintenance);GO:0003887(DNA-directed DNA polymerase activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005730(nucleolus);GO:0005739(mitochondrion);GO:0005829(cytosol);GO:0006260(DNA replication);GO:0006261(DNA-dependent DNA replication);GO:0006281(DNA repair);GO:0006283(transcription-coupled nucleotide-excision repair);GO:0006296(nucleotide-excision repair, DNA incision, 5'-to lesion);GO:0006297(nucleotide-excision repair, DNA gap filling);GO:0006298(mismatch repair);GO:0006974(cellular response to DNA damage stimulus);GO:0019985(translesion synthesis);GO:0032201(telomere maintenance via semi-conservative replication);GO:0033683(nucleotide-excision repair, DNA incision);GO:0042769(DNA damage response, detection of DNA damage);GO:0043625(delta DNA polymerase complex)","03030(DNA replication);03410(Base excision repair);03420(Nucleotide excision repair);03430(Mismatch repair);03440(Homologous recombination)","K03505","NA","DNA polymerase delta 4, accessory subunit [Source:HGNC Symbol;Acc:HGNC:14106]",{"v":2.102442,"d":"2.10"},{"v":1.633072,"d":"1.63"},{"v":0.030717,"d":"0.03"},{"v":0.076185,"d":"0.08"},{"v":0.013776,"d":"0.01"},{"v":0.08831,"d":"0.09"},{"v":21.1264367171329,"d":"21.13"},{"v":4.40097755103731,"d":"4.40"},{"v":0.00379324933046215,"d":"0.00"},{"v":0.188779107089986,"d":"0.19"},"up","yes"]
[55811,0,"chr14","-",34561094,34630109,"ENST00000396526",13,3398,"ENSG00000129515","SNX6","GO:0005515(protein binding);GO:0005623(cell);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005764(lysosome);GO:0005768(endosome);GO:0005769(early endosome);GO:0005829(cytosol);GO:0006886(intracellular protein transport);GO:0007175(negative regulation of epidermal growth factor-activated receptor activity);GO:0008289(lipid binding);GO:0015031(protein transport);GO:0016020(membrane);GO:0016241(regulation of macroautophagy);GO:0030512(negative regulation of transforming growth factor beta receptor signaling pathway);GO:0030904(retromer complex);GO:0030905(retromer, tubulation complex);GO:0031410(cytoplasmic vesicle);GO:0031901(early endosome membrane);GO:0034452(dynactin binding);GO:0034713(type I transforming growth factor beta receptor binding);GO:0035091(phosphatidylinositol binding);GO:0042147(retrograde transport, endosome to Golgi);GO:0042803(protein homodimerization activity);GO:0043524(negative regulation of neuron apoptotic process);GO:0045892(negative regulation of transcription, DNA-templated);GO:0046982(protein heterodimerization activity);GO:0071364(cellular response to epidermal growth factor stimulus);GO:0097422(tubular endosome);GO:1904646(cellular response to amyloid-beta)","04144(Endocytosis)","K17920","NA","sorting nexin 6 [Source:HGNC Symbol;Acc:HGNC:14970]",{"v":11.610551,"d":"11.61"},{"v":0.396121,"d":"0.40"},{"v":4.744435,"d":"4.74"},{"v":0.291187,"d":"0.29"},{"v":0.500848,"d":"0.50"},{"v":0.820254,"d":"0.82"},{"v":10.3896429238182,"d":"10.39"},{"v":3.37707416675326,"d":"3.38"},{"v":0.00383226616609172,"d":"0.00"},{"v":0.190459958706036,"d":"0.19"},"up","yes"]
[184832,0,"chr7","-",142941114,142962363,"ENST00000355265",19,2494,"ENSG00000197993","KEL","GO:0004222(metalloendopeptidase activity);GO:0005515(protein binding);GO:0005623(cell);GO:0005886(plasma membrane);GO:0006508(proteolysis);GO:0006874(cellular calcium ion homeostasis);GO:0008233(peptidase activity);GO:0008237(metallopeptidase activity);GO:0008361(regulation of cell size);GO:0010961(cellular magnesium ion homeostasis);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016787(hydrolase activity);GO:0031133(regulation of axon diameter);GO:0042310(vasoconstriction);GO:0042552(myelination);GO:0046872(metal ion binding);GO:0048741(skeletal muscle fiber development);GO:1901380(negative regulation of potassium ion transmembrane transport)","NA","K06577","EC:3.4.24.-","Kell metallo-endopeptidase (Kell blood group) [Source:HGNC Symbol;Acc:HGNC:6308]",{"v":0.008418,"d":"0.01"},{"v":0.048806,"d":"0.05"},{"v":0.026444,"d":"0.03"},{"v":0.37555,"d":"0.38"},{"v":0.407026,"d":"0.41"},{"v":0.645052,"d":"0.65"},{"v":0.0586063036028994,"d":"0.06"},{"v":-4.09280034274585,"d":"-4.09"},{"v":0.00385139113811557,"d":"0.00"},{"v":0.191148961813851,"d":"0.19"},"down","yes"]
[119980,0,"chr2","+",182718067,182740206,"ENST00000537515",10,1669,"ENSG00000077232","DNAJC10","GO:0001671(ATPase activator activity);GO:0001933(negative regulation of protein phosphorylation);GO:0005515(protein binding);GO:0005623(cell);GO:0005783(endoplasmic reticulum);GO:0005788(endoplasmic reticulum lumen);GO:0015035(protein disulfide oxidoreductase activity);GO:0015036(disulfide oxidoreductase activity);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016491(oxidoreductase activity);GO:0016671(oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor);GO:0030433(ubiquitin-dependent ERAD pathway);GO:0030544(Hsp70 protein binding);GO:0032781(positive regulation of ATPase activity);GO:0034663(endoplasmic reticulum chaperone complex);GO:0034975(protein folding in endoplasmic reticulum);GO:0034976(response to endoplasmic reticulum stress);GO:0045454(cell redox homeostasis);GO:0051087(chaperone binding);GO:0051117(ATPase binding);GO:0051787(misfolded protein binding);GO:0055114(oxidation-reduction process);GO:0070059(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)","04141(Protein processing in endoplasmic reticulum)","K09530","NA","DnaJ heat shock protein family (Hsp40) member C10 [Source:HGNC Symbol;Acc:HGNC:24637]",{"v":6.256129,"d":"6.26"},{"v":5.169572,"d":"5.17"},{"v":6.365545,"d":"6.37"},{"v":0.801383,"d":"0.80"},{"v":0.88109,"d":"0.88"},{"v":0.740262,"d":"0.74"},{"v":7.3434552272535,"d":"7.34"},{"v":2.87645903668044,"d":"2.88"},{"v":0.00387354526171163,"d":"0.00"},{"v":0.191986220133675,"d":"0.19"},"up","yes"]
[136127,0,"chr3","+",319683,409412,"ENST00000620033",25,7311,"ENSG00000134121","CHL1","GO:0001764(neuron migration);GO:0002020(protease binding);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0005886(plasma membrane);GO:0007155(cell adhesion);GO:0007165(signal transduction);GO:0007275(multicellular organism development);GO:0007399(nervous system development);GO:0007411(axon guidance);GO:0008344(adult locomotory behavior);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0030154(cell differentiation);GO:0030425(dendrite);GO:0031175(neuron projection development);GO:0035640(exploration behavior);GO:0043524(negative regulation of neuron apoptotic process);GO:0045177(apical part of cell);GO:0050890(cognition);GO:0070062(extracellular exosome)","NA","K06758","NA","cell adhesion molecule L1 like [Source:HGNC Symbol;Acc:HGNC:1939]",{"v":2.003378,"d":"2.00"},{"v":1.561378,"d":"1.56"},{"v":1.893711,"d":"1.89"},0,{"v":0.141219,"d":"0.14"},0,{"v":38.6524971852229,"d":"38.65"},{"v":5.27248971887856,"d":"5.27"},{"v":0.00391787090705904,"d":"0.00"},{"v":0.193918596803072,"d":"0.19"},"up","yes"]
[53474,0,"chr13","-",112485011,112588153,"ENST00000261965",22,3879,"ENSG00000126216","TUBGCP3","GO:0000226(microtubule cytoskeleton organization);GO:0000278(mitotic cell cycle);GO:0000922(spindle pole);GO:0000923(equatorial microtubule organizing center);GO:0000930(gamma-tubulin complex);GO:0005198(structural molecule activity);GO:0005200(structural constituent of cytoskeleton);GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0005813(centrosome);GO:0005814(centriole);GO:0005815(microtubule organizing center);GO:0005819(spindle);GO:0005827(polar microtubule);GO:0005829(cytosol);GO:0005856(cytoskeleton);GO:0005874(microtubule);GO:0007020(microtubule nucleation);GO:0007338(single fertilization);GO:0008275(gamma-tubulin small complex);GO:0016020(membrane);GO:0031122(cytoplasmic microtubule organization);GO:0043015(gamma-tubulin binding);GO:0051011(microtubule minus-end binding);GO:0051225(spindle assembly);GO:0051321(meiotic cell cycle);GO:0051415(microtubule nucleation by interphase microtubule organizing center)","NA","K16570","NA","tubulin gamma complex associated protein 3 [Source:HGNC Symbol;Acc:HGNC:18598]",{"v":2.581358,"d":"2.58"},{"v":0.480823,"d":"0.48"},{"v":3.147341,"d":"3.15"},{"v":0.259908,"d":"0.26"},{"v":0.135229,"d":"0.14"},{"v":0.241071,"d":"0.24"},{"v":9.7602073535699,"d":"9.76"},{"v":3.28691179786903,"d":"3.29"},{"v":0.0039499737030729,"d":"0.00"},{"v":0.195241557323318,"d":"0.20"},"up","yes"]
[23887,0,"chr10","+",102152176,102163871,"ENST00000405356",13,3967,"ENSG00000166197","NOLC1","GO:0000166(nucleotide binding);GO:0000278(mitotic cell cycle);GO:0001042(RNA polymerase I core binding);GO:0001650(fibrillar center);GO:0003677(DNA binding);GO:0003700(DNA-binding transcription factor activity);GO:0003723(RNA binding);GO:0005515(protein binding);GO:0005524(ATP binding);GO:0005525(GTP binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005730(nucleolus);GO:0005737(cytoplasm);GO:0006364(rRNA processing);GO:0006417(regulation of translation);GO:0006970(response to osmotic stress);GO:0007000(nucleolus organization);GO:0008134(transcription factor binding);GO:0008139(nuclear localization sequence binding);GO:0008284(positive regulation of cell population proliferation);GO:0014029(neural crest formation);GO:0014032(neural crest cell development);GO:0015030(Cajal body);GO:0019904(protein domain specific binding);GO:0031428(box C/D snoRNP complex);GO:0031429(box H/ACA snoRNP complex);GO:0033979(box H/ACA snoRNA metabolic process);GO:0034512(box C/D snoRNA binding);GO:0034513(box H/ACA snoRNA binding);GO:0042306(regulation of protein import into nucleus);GO:0045893(positive regulation of transcription, DNA-templated);GO:0046982(protein heterodimerization activity);GO:0062064(box C/D snoRNP complex binding);GO:0062065(box H/ACA snoRNP complex binding)","NA","NA","NA","nucleolar and coiled-body phosphoprotein 1 [Source:HGNC Symbol;Acc:HGNC:15608]",{"v":0.087386,"d":"0.09"},{"v":0.070615,"d":"0.07"},{"v":0.060211,"d":"0.06"},{"v":0.080006,"d":"0.08"},{"v":1.768543,"d":"1.77"},{"v":0.989576,"d":"0.99"},{"v":0.0768859722528078,"d":"0.08"},{"v":-3.70113578544164,"d":"-3.70"},{"v":0.00397814179931779,"d":"0.00"},{"v":0.196366700501651,"d":"0.20"},"down","yes"]
[4652,0,"chr1","-",39560816,39576253,"ENST00000372862",15,2470,"ENSG00000090621","PABPC4","GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0003729(mRNA binding);GO:0003730(mRNA 3'-UTR binding);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0006396(RNA processing);GO:0006401(RNA catabolic process);GO:0006412(translation);GO:0007596(blood coagulation);GO:0008143(poly(A) binding);GO:0008266(poly(U) RNA binding);GO:0010494(cytoplasmic stress granule);GO:0043488(regulation of mRNA stability);GO:0061515(myeloid cell development);GO:1990904(ribonucleoprotein complex)","03013(RNA transport);03015(mRNA surveillance pathway);03018(RNA degradation)","K13126","NA","poly(A) binding protein cytoplasmic 4 [Source:HGNC Symbol;Acc:HGNC:8557]",{"v":1.439165,"d":"1.44"},{"v":0.693072,"d":"0.69"},{"v":0.639664,"d":"0.64"},{"v":0.814859,"d":"0.81"},{"v":0.924633,"d":"0.92"},{"v":37.036747,"d":"37.04"},{"v":0.0714845243242904,"d":"0.07"},{"v":-3.8062252429491,"d":"-3.81"},{"v":0.0040093554948494,"d":"0.00"},{"v":0.197638921476091,"d":"0.20"},"down","yes"]
[166359,0,"chr5","+",179698417,179728907,"ENST00000504734",15,2232,"ENSG00000127022","CANX","GO:0002474(antigen processing and presentation of peptide antigen via MHC class I);GO:0003723(RNA binding);GO:0005509(calcium ion binding);GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0005783(endoplasmic reticulum);GO:0005788(endoplasmic reticulum lumen);GO:0005789(endoplasmic reticulum membrane);GO:0005790(smooth endoplasmic reticulum);GO:0005791(rough endoplasmic reticulum);GO:0005840(ribosome);GO:0006457(protein folding);GO:0007568(aging);GO:0009306(protein secretion);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0019886(antigen processing and presentation of exogenous peptide antigen via MHC class II);GO:0030246(carbohydrate binding);GO:0030424(axon);GO:0032839(dendrite cytoplasm);GO:0032991(protein-containing complex);GO:0034185(apolipoprotein binding);GO:0034975(protein folding in endoplasmic reticulum);GO:0035255(ionotropic glutamate receptor binding);GO:0042470(melanosome);GO:0043025(neuronal cell body);GO:0043197(dendritic spine);GO:0044233(mitochondria-associated endoplasmic reticulum membrane);GO:0044322(endoplasmic reticulum quality control compartment);GO:0046872(metal ion binding);GO:0048488(synaptic vesicle endocytosis);GO:0051082(unfolded protein binding);GO:0070062(extracellular exosome);GO:0070106(interleukin-27-mediated signaling pathway);GO:0070757(interleukin-35-mediated signaling pathway);GO:0071556(integral component of lumenal side of endoplasmic reticulum membrane);GO:0072583(clathrin-dependent endocytosis);GO:0098978(glutamatergic synapse);GO:0099055(integral component of postsynaptic membrane);GO:0099059(integral component of presynaptic active zone membrane)","04141(Protein processing in endoplasmic reticulum);04145(Phagosome);04612(Antigen processing and presentation);04918(Thyroid hormone synthesis);05166(Human T-cell leukemia virus 1 infection)","NA","NA","calnexin [Source:HGNC Symbol;Acc:HGNC:1473]",0,{"v":0.051738,"d":"0.05"},0,{"v":0.380755,"d":"0.38"},{"v":1.52618,"d":"1.53"},{"v":0.226912,"d":"0.23"},{"v":0.0242463494336754,"d":"0.02"},{"v":-5.36608864042921,"d":"-5.37"},{"v":0.00403472151275897,"d":"0.00"},{"v":0.198619827315086,"d":"0.20"},"down","yes"]
[28933,0,"chr11","+",33258331,33357020,"ENST00000456517",16,7399,"ENSG00000110422","HIPK3","GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005524(ATP binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0006468(protein phosphorylation);GO:0006915(apoptotic process);GO:0009299(mRNA transcription);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0016604(nuclear body);GO:0016605(PML body);GO:0016740(transferase activity);GO:0018105(peptidyl-serine phosphorylation);GO:0018107(peptidyl-threonine phosphorylation);GO:0043066(negative regulation of apoptotic process);GO:0043508(negative regulation of JUN kinase activity)","04218(Cellular senescence)","K08826","EC:2.7.11.1","homeodomain interacting protein kinase 3 [Source:HGNC Symbol;Acc:HGNC:4915]",{"v":4.780969,"d":"4.78"},{"v":6.059415,"d":"6.06"},{"v":7.366882,"d":"7.37"},{"v":1.131769,"d":"1.13"},{"v":0.003506,"d":"0.00"},{"v":0.350713,"d":"0.35"},{"v":12.2526332648716,"d":"12.25"},{"v":3.6150199330877,"d":"3.62"},{"v":0.00404425275992148,"d":"0.00"},{"v":0.198819624855138,"d":"0.20"},"up","yes"]
[90318,0,"chr17","+",75588058,75616390,"ENST00000584516",33,5709,"ENSG00000266714","MYO15B","GO:0000166(nucleotide binding);GO:0003674(molecular_function);GO:0003774(motor activity);GO:0003779(actin binding);GO:0005515(protein binding);GO:0005524(ATP binding);GO:0005575(cellular_component);GO:0005737(cytoplasm);GO:0005856(cytoskeleton);GO:0005903(brush border);GO:0008150(biological_process);GO:0016459(myosin complex)","NA","K10361","NA","myosin XVB [Source:HGNC Symbol;Acc:HGNC:14083]",{"v":0.36024,"d":"0.36"},{"v":0.395657,"d":"0.40"},{"v":0.624404,"d":"0.62"},{"v":0.010052,"d":"0.01"},{"v":0.022715,"d":"0.02"},{"v":0.092806,"d":"0.09"},{"v":10.992020577672,"d":"10.99"},{"v":3.45838470496365,"d":"3.46"},{"v":0.00407115076910986,"d":"0.00"},{"v":0.199871496542921,"d":"0.20"},"up","yes"]
[97310,0,"chr19","-",3958454,3969828,"ENST00000301264",8,2105,"ENSG00000167657","DAPK3","GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005515(protein binding);GO:0005524(ATP binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005884(actin filament);GO:0006325(chromatin organization);GO:0006355(regulation of transcription, DNA-templated);GO:0006417(regulation of translation);GO:0006468(protein phosphorylation);GO:0006915(apoptotic process);GO:0006940(regulation of smooth muscle contraction);GO:0007088(regulation of mitotic nuclear division);GO:0007346(regulation of mitotic cell cycle);GO:0008022(protein C-terminus binding);GO:0008140(cAMP response element binding protein binding);GO:0008360(regulation of cell shape);GO:0010506(regulation of autophagy);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0016605(PML body);GO:0016740(transferase activity);GO:0017048(Rho GTPase binding);GO:0017148(negative regulation of translation);GO:0030182(neuron differentiation);GO:0030335(positive regulation of cell migration);GO:0035556(intracellular signal transduction);GO:0042802(identical protein binding);GO:0042803(protein homodimerization activity);GO:0042981(regulation of apoptotic process);GO:0043065(positive regulation of apoptotic process);GO:0043519(regulation of myosin II filament organization);GO:0043522(leucine zipper domain binding);GO:0045121(membrane raft);GO:0046777(protein autophosphorylation);GO:0051893(regulation of focal adhesion assembly);GO:0071346(cellular response to interferon-gamma);GO:0090263(positive regulation of canonical Wnt signaling pathway);GO:0097190(apoptotic signaling pathway);GO:2000145(regulation of cell motility);GO:2000249(regulation of actin cytoskeleton reorganization);GO:2001241(positive regulation of extrinsic apoptotic signaling pathway in absence of ligand)","04140(Autophagy - animal);05200(Pathways in cancer);05219(Bladder cancer)","K08803","EC:2.7.11.1","death associated protein kinase 3 [Source:HGNC Symbol;Acc:HGNC:2676]",{"v":28.131823,"d":"28.13"},{"v":14.929552,"d":"14.93"},{"v":0.691116,"d":"0.69"},{"v":2.341321,"d":"2.34"},{"v":1.430929,"d":"1.43"},{"v":0.373701,"d":"0.37"},{"v":10.5530651471761,"d":"10.55"},{"v":3.39959018674598,"d":"3.40"},{"v":0.00408694034950898,"d":"0.00"},{"v":0.200375901346371,"d":"0.20"},"up","yes"]
[117214,0,"chr2","+",130342894,130347351,"ENST00000462392",7,1793,"ENSG00000136718","IMP4","GO:0001650(fibrillar center);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005730(nucleolus);GO:0006364(rRNA processing);GO:0030515(snoRNA binding);GO:0030684(preribosome);GO:0032040(small-subunit processome);GO:0034457(Mpp10 complex);GO:0042254(ribosome biogenesis)","03008(Ribosome biogenesis in eukaryotes)","K14561","NA","IMP4, U3 small nucleolar ribonucleoprotein [Source:HGNC Symbol;Acc:HGNC:30856]",{"v":5.512139,"d":"5.51"},{"v":5.723633,"d":"5.72"},0,0,{"v":0.08869,"d":"0.09"},0,{"v":126.685894689367,"d":"126.69"},{"v":6.98511209235501,"d":"6.99"},{"v":0.00410263109766201,"d":"0.00"},{"v":0.200874107517602,"d":"0.20"},"up","yes"]
[183422,0,"chr7","-",122319746,122886458,"ENST00000412584",28,4308,"ENSG00000081803","CADPS2","GO:0005654(nucleoplasm);GO:0006887(exocytosis);GO:0008289(lipid binding);GO:0009267(cellular response to starvation);GO:0015031(protein transport);GO:0016020(membrane);GO:0016079(synaptic vesicle exocytosis);GO:0016082(synaptic vesicle priming);GO:0030054(cell junction);GO:0030659(cytoplasmic vesicle membrane);GO:0031410(cytoplasmic vesicle);GO:0042734(presynaptic membrane);GO:0043231(intracellular membrane-bounded organelle);GO:0045202(synapse);GO:0045211(postsynaptic membrane);GO:0045921(positive regulation of exocytosis);GO:0046872(metal ion binding);GO:0098688(parallel fiber to Purkinje cell synapse);GO:0098793(presynapse);GO:0098978(glutamatergic synapse);GO:1990504(dense core granule exocytosis)","NA","K19933","NA","calcium dependent secretion activator 2 [Source:HGNC Symbol;Acc:HGNC:16018]",0,0,{"v":0.039716,"d":"0.04"},{"v":1.139932,"d":"1.14"},{"v":0.508286,"d":"0.51"},{"v":0.026211,"d":"0.03"},{"v":0.0237191305215091,"d":"0.02"},{"v":-5.39780506417824,"d":"-5.40"},{"v":0.00416826775497814,"d":"0.00"},{"v":0.203813146081233,"d":"0.20"},"down","yes"]
[204984,0,"chrX","-",101655281,101659850,"ENST00000356824",6,2819,"ENSG00000184867","ARMCX2","GO:0005515(protein binding);GO:0005739(mitochondrion);GO:0005741(mitochondrial outer membrane);GO:0016020(membrane);GO:0016021(integral component of membrane)","NA","NA","NA","armadillo repeat containing X-linked 2 [Source:HGNC Symbol;Acc:HGNC:16869]",{"v":1.840105,"d":"1.84"},{"v":1.65095,"d":"1.65"},{"v":1.886265,"d":"1.89"},{"v":2.28542,"d":"2.29"},{"v":15.106196,"d":"15.11"},{"v":14.654823,"d":"14.65"},{"v":0.167797738775282,"d":"0.17"},{"v":-2.5752048205856,"d":"-2.58"},{"v":0.00419776104479808,"d":"0.00"},{"v":0.204979380050423,"d":"0.20"},"down","yes"]
[101023,0,"chr19","-",18442663,18522070,"ENST00000262809",12,3970,"ENSG00000105656","ELL","GO:0001701(in utero embryonic development);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0006366(transcription by RNA polymerase II);GO:0006368(transcription elongation from RNA polymerase II promoter);GO:0008023(transcription elongation factor complex);GO:0010923(negative regulation of phosphatase activity);GO:0015030(Cajal body);GO:0016607(nuclear speck);GO:0019902(phosphatase binding);GO:0032786(positive regulation of DNA-templated transcription, elongation);GO:0032968(positive regulation of transcription elongation from RNA polymerase II promoter);GO:0035327(transcriptionally active chromatin);GO:0035363(histone locus body);GO:0042795(snRNA transcription by RNA polymerase II);GO:0042796(snRNA transcription by RNA polymerase III);GO:0045945(positive regulation of transcription by RNA polymerase III)","NA","NA","NA","elongation factor for RNA polymerase II [Source:HGNC Symbol;Acc:HGNC:23114]",{"v":3.036351,"d":"3.04"},{"v":0.304445,"d":"0.30"},{"v":0.242816,"d":"0.24"},{"v":0.104325,"d":"0.10"},{"v":0.092668,"d":"0.09"},{"v":0.058456,"d":"0.06"},{"v":14.0286789143821,"d":"14.03"},{"v":3.81030725114329,"d":"3.81"},{"v":0.00420412278995721,"d":"0.00"},{"v":0.205014471086101,"d":"0.21"},"up","yes"]
[142764,0,"chr3","+",111883963,111976289,"ENST00000481953",16,5474,"ENSG00000144824","PHLDB2","GO:0000226(microtubule cytoskeleton organization);GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0005925(focal adhesion);GO:0010470(regulation of gastrulation);GO:0010717(regulation of epithelial to mesenchymal transition);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0031252(cell leading edge);GO:0045111(intermediate filament cytoskeleton);GO:0045180(basal cortex);GO:0045184(establishment of protein localization);GO:0045296(cadherin binding);GO:0051497(negative regulation of stress fiber assembly);GO:0051895(negative regulation of focal adhesion assembly);GO:0070507(regulation of microtubule cytoskeleton organization);GO:1903690(negative regulation of wound healing, spreading of epidermal cells);GO:1904261(positive regulation of basement membrane assembly involved in embryonic body morphogenesis)","NA","NA","NA","pleckstrin homology like domain family B member 2 [Source:HGNC Symbol;Acc:HGNC:29573]",0,{"v":0.000362,"d":"0.00"},{"v":0.00225,"d":"0.00"},{"v":0.171937,"d":"0.17"},{"v":0.206966,"d":"0.21"},{"v":0.00048,"d":"0.00"},{"v":0.00688486305395866,"d":"0.01"},{"v":-7.18235632650223,"d":"-7.18"},{"v":0.00422740085617636,"d":"0.00"},{"v":0.205873288344353,"d":"0.21"},"down","yes"]
[154416,0,"chr4","+",119212636,119294746,"ENST00000274030",19,5936,"ENSG00000145390","USP53","GO:0001508(action potential);GO:0005515(protein binding);GO:0005575(cellular_component);GO:0005911(cell-cell junction);GO:0005923(bicellular tight junction);GO:0006915(apoptotic process);GO:0007605(sensory perception of sound);GO:0008150(biological_process);GO:0010996(response to auditory stimulus);GO:0016579(protein deubiquitination);GO:0030054(cell junction);GO:0036459(thiol-dependent ubiquitinyl hydrolase activity);GO:0051402(neuron apoptotic process)","NA","NA","NA","ubiquitin specific peptidase 53 [Source:HGNC Symbol;Acc:HGNC:29255]",{"v":0.122904,"d":"0.12"},{"v":0.026602,"d":"0.03"},{"v":0.075691,"d":"0.08"},{"v":0.451296,"d":"0.45"},{"v":1.021362,"d":"1.02"},{"v":0.699689,"d":"0.70"},{"v":0.103665298407667,"d":"0.10"},{"v":-3.26999505699059,"d":"-3.27"},{"v":0.00423389444774043,"d":"0.00"},{"v":0.205913501052758,"d":"0.21"},"down","yes"]
[121484,0,"chr2","-",208236232,208254458,"ENST00000446179",10,2298,"ENSG00000138413","IDH1","GO:0000287(magnesium ion binding);GO:0004448(isocitrate dehydrogenase activity);GO:0004450(isocitrate dehydrogenase (NADP+) activity);GO:0005102(signaling receptor binding);GO:0005576(extracellular region);GO:0005737(cytoplasm);GO:0005739(mitochondrion);GO:0005777(peroxisome);GO:0005782(peroxisomal matrix);GO:0005829(cytosol);GO:0006097(glyoxylate cycle);GO:0006099(tricarboxylic acid cycle);GO:0006102(isocitrate metabolic process);GO:0006103(2-oxoglutarate metabolic process);GO:0006625(protein targeting to peroxisome);GO:0006739(NADP metabolic process);GO:0006740(NADPH regeneration);GO:0006749(glutathione metabolic process);GO:0006979(response to oxidative stress);GO:0008585(female gonad development);GO:0014070(response to organic cyclic compound);GO:0016491(oxidoreductase activity);GO:0016616(oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor);GO:0034774(secretory granule lumen);GO:0042802(identical protein binding);GO:0042803(protein homodimerization activity);GO:0043312(neutrophil degranulation);GO:0045296(cadherin binding);GO:0046872(metal ion binding);GO:0048545(response to steroid hormone);GO:0050661(NADP binding);GO:0051287(NAD binding);GO:0055114(oxidation-reduction process);GO:0060696(regulation of phospholipid catabolic process);GO:0070062(extracellular exosome);GO:0071071(regulation of phospholipid biosynthetic process);GO:1904724(tertiary granule lumen);GO:1904813(ficolin-1-rich granule lumen)","00020(Citrate cycle (TCA cycle));00480(Glutathione metabolism);04146(Peroxisome);05230(Central carbon metabolism in cancer)","NA","NA","isocitrate dehydrogenase (NADP(+)) 1, cytosolic [Source:HGNC Symbol;Acc:HGNC:5382]",{"v":1.284367,"d":"1.28"},{"v":1.122696,"d":"1.12"},{"v":60.584152,"d":"60.58"},{"v":0.954843,"d":"0.95"},{"v":2.096345,"d":"2.10"},{"v":1.635697,"d":"1.64"},{"v":13.4398891801271,"d":"13.44"},{"v":3.74844933717515,"d":"3.75"},{"v":0.00426134821508483,"d":"0.00"},{"v":0.206971631890417,"d":"0.21"},"up","yes"]
[3310,0,"chr1","-",27355184,27366961,"ENST00000357582",29,4438,"ENSG00000142733","MAP3K6","GO:0000166(nucleotide binding);GO:0000186(activation of MAPKK activity);GO:0000287(magnesium ion binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0004709(MAP kinase kinase kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0007165(signal transduction);GO:0007257(activation of JUN kinase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0016740(transferase activity);GO:0046872(metal ion binding)","04010(MAPK signaling pathway)","NA","NA","mitogen-activated protein kinase kinase kinase 6 [Source:HGNC Symbol;Acc:HGNC:6858]",{"v":0.393306,"d":"0.39"},{"v":0.214889,"d":"0.21"},{"v":0.272257,"d":"0.27"},{"v":0.329197,"d":"0.33"},{"v":3.941467,"d":"3.94"},{"v":4.131337,"d":"4.13"},{"v":0.104790751631665,"d":"0.10"},{"v":-3.25441669827817,"d":"-3.25"},{"v":0.0043222930685378,"d":"0.00"},{"v":0.209651411455245,"d":"0.21"},"down","yes"]
[158768,0,"chr5","-",43527092,43557093,"ENST00000436644",11,1734,"ENSG00000172239","PAIP1","GO:0003723(RNA binding);GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0006413(translational initiation);GO:0006417(regulation of translation);GO:0006446(regulation of translational initiation);GO:0008494(translation activator activity);GO:0045727(positive regulation of translation);GO:0048255(mRNA stabilization)","03013(RNA transport)","K14322","NA","poly(A) binding protein interacting protein 1 [Source:HGNC Symbol;Acc:HGNC:16945]",{"v":24.083021,"d":"24.08"},{"v":22.719885,"d":"22.72"},{"v":27.119064,"d":"27.12"},{"v":8.146393,"d":"8.15"},{"v":2.706087,"d":"2.71"},{"v":4.938417,"d":"4.94"},{"v":4.68130277842988,"d":"4.68"},{"v":2.22691007904531,"d":"2.23"},{"v":0.00435881923737597,"d":"0.00"},{"v":0.211141203858492,"d":"0.21"},"up","yes"]
[116267,0,"chr2","+",111120914,111168445,"ENST00000620862",6,5044,"ENSG00000153094","BCL2L11","GO:0001701(in utero embryonic development);GO:0001776(leukocyte homeostasis);GO:0001782(B cell homeostasis);GO:0001783(B cell apoptotic process);GO:0001822(kidney development);GO:0001844(protein insertion into mitochondrial membrane involved in apoptotic signaling pathway);GO:0002260(lymphocyte homeostasis);GO:0002262(myeloid cell homeostasis);GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0005739(mitochondrion);GO:0005741(mitochondrial outer membrane);GO:0005829(cytosol);GO:0006915(apoptotic process);GO:0007160(cell-matrix adhesion);GO:0007283(spermatogenesis);GO:0007420(brain development);GO:0008017(microtubule binding);GO:0008584(male gonad development);GO:0008630(intrinsic apoptotic signaling pathway in response to DNA damage);GO:0009791(post-embryonic development);GO:0010942(positive regulation of cell death);GO:0012505(endomembrane system);GO:0016020(membrane);GO:0019898(extrinsic component of membrane);GO:0019901(protein kinase binding);GO:0030879(mammary gland development);GO:0032464(positive regulation of protein homooligomerization);GO:0034263(positive regulation of autophagy in response to ER overload);GO:0034976(response to endoplasmic reticulum stress);GO:0035148(tube formation);GO:0042475(odontogenesis of dentin-containing tooth);GO:0042981(regulation of apoptotic process);GO:0043029(T cell homeostasis);GO:0043065(positive regulation of apoptotic process);GO:0043231(intracellular membrane-bounded organelle);GO:0043280(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process);GO:0043525(positive regulation of neuron apoptotic process);GO:0043583(ear development);GO:0045787(positive regulation of cell cycle);GO:0046620(regulation of organ growth);GO:0046982(protein heterodimerization activity);GO:0048066(developmental pigmentation);GO:0048070(regulation of developmental pigmentation);GO:0048536(spleen development);GO:0048538(thymus development);GO:0048563(post-embryonic animal organ morphogenesis);GO:0060139(positive regulation of apoptotic process by virus);GO:0060154(cellular process regulating host cell cycle in response to virus);GO:0070242(thymocyte apoptotic process);GO:0071385(cellular response to glucocorticoid stimulus);GO:0090200(positive regulation of release of cytochrome c from mitochondria);GO:0097136(Bcl-2 family protein complex);GO:0097192(extrinsic apoptotic signaling pathway in absence of ligand);GO:1902110(positive regulation of mitochondrial membrane permeability involved in apoptotic process);GO:1902237(positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway);GO:1902263(apoptotic process involved in embryonic digit morphogenesis);GO:1903896(positive regulation of IRE1-mediated unfolded protein response);GO:2000271(positive regulation of fibroblast apoptotic process);GO:2001244(positive regulation of intrinsic apoptotic signaling pathway)","01521(EGFR tyrosine kinase inhibitor resistance);04068(FoxO signaling pathway);04151(PI3K-Akt signaling pathway);04210(Apoptosis);04215(Apoptosis - multiple species);04932(Non-alcoholic fatty liver disease (NAFLD));05169(Epstein-Barr virus infection);05200(Pathways in cancer);05206(MicroRNAs in cancer);05210(Colorectal cancer)","NA","NA","BCL2 like 11 [Source:HGNC Symbol;Acc:HGNC:994]",{"v":0.40324,"d":"0.40"},{"v":0.14901,"d":"0.15"},{"v":0.419778,"d":"0.42"},{"v":0.498916,"d":"0.50"},{"v":3.841637,"d":"3.84"},{"v":4.113367,"d":"4.11"},{"v":0.114979559778186,"d":"0.11"},{"v":-3.12055068265389,"d":"-3.12"},{"v":0.00440465628661752,"d":"0.00"},{"v":0.21281540333781,"d":"0.21"},"down","yes"]
[164118,0,"chr5","-",147390808,147510068,"ENST00000343218",14,5492,"ENSG00000113657","DPYSL3","GO:0005515(protein binding);GO:0005615(extracellular space);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0010975(regulation of neuron projection development);GO:0010976(positive regulation of neuron projection development);GO:0010977(negative regulation of neuron projection development);GO:0016787(hydrolase activity);GO:0016810(hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds);GO:0017124(SH3 domain binding);GO:0030027(lamellipodium);GO:0030334(regulation of cell migration);GO:0030336(negative regulation of cell migration);GO:0030426(growth cone);GO:0031005(filamin binding);GO:0031941(filamentous actin);GO:0035374(chondroitin sulfate binding);GO:0042995(cell projection);GO:0044297(cell body);GO:0045202(synapse);GO:0048666(neuron development);GO:0048678(response to axon injury);GO:0051017(actin filament bundle assembly);GO:0051260(protein homooligomerization);GO:0051491(positive regulation of filopodium assembly);GO:0051764(actin crosslink formation);GO:0070382(exocytic vesicle);GO:0071345(cellular response to cytokine stimulus)","NA","NA","NA","dihydropyrimidinase like 3 [Source:HGNC Symbol;Acc:HGNC:3015]",{"v":4.702771,"d":"4.70"},{"v":7.707937,"d":"7.71"},{"v":3.317368,"d":"3.32"},{"v":27.014143,"d":"27.01"},{"v":39.712421,"d":"39.71"},{"v":6.682601,"d":"6.68"},{"v":0.214252212240801,"d":"0.21"},{"v":-2.22261799406251,"d":"-2.22"},{"v":0.0044050972559877,"d":"0.00"},{"v":0.21281540333781,"d":"0.21"},"down","yes"]
[27574,0,"chr11","-",10797053,10807462,"ENST00000525681",21,3654,"ENSG00000110321","EIF4G2","GO:0003723(RNA binding);GO:0003729(mRNA binding);GO:0003743(translation initiation factor activity);GO:0005515(protein binding);GO:0005829(cytosol);GO:0005913(cell-cell adherens junction);GO:0006412(translation);GO:0006413(translational initiation);GO:0006417(regulation of translation);GO:0006446(regulation of translational initiation);GO:0007050(cell cycle arrest);GO:0007507(heart development);GO:0008135(translation factor activity, RNA binding);GO:0008219(cell death);GO:0010507(negative regulation of autophagy);GO:0016020(membrane);GO:0016281(eukaryotic translation initiation factor 4F complex);GO:0030307(positive regulation of cell growth);GO:0030424(axon);GO:0034645(cellular macromolecule biosynthetic process);GO:0045296(cadherin binding);GO:0045727(positive regulation of translation);GO:0045773(positive regulation of axon extension);GO:0060999(positive regulation of dendritic spine development)","03013(RNA transport);05416(Viral myocarditis)","K03260","NA","eukaryotic translation initiation factor 4 gamma 2 [Source:HGNC Symbol;Acc:HGNC:3297]",{"v":0.006521,"d":"0.01"},{"v":33.423512,"d":"33.42"},{"v":0.116786,"d":"0.12"},{"v":0.259859,"d":"0.26"},{"v":0.266217,"d":"0.27"},{"v":0.003179,"d":"0.00"},{"v":63.3849826643112,"d":"63.38"},{"v":5.98606916865837,"d":"5.99"},{"v":0.00447688954800453,"d":"0.00"},{"v":0.215996543531215,"d":"0.22"},"up","yes"]
[118863,0,"chr2","+",168456249,168775134,"ENST00000392687",11,6851,"ENSG00000172292","CERS6","GO:0000981(DNA-binding transcription factor activity, RNA polymerase II-specific);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0006357(regulation of transcription by RNA polymerase II);GO:0006629(lipid metabolic process);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0030148(sphingolipid biosynthetic process);GO:0031965(nuclear membrane);GO:0046513(ceramide biosynthetic process);GO:0050291(sphingosine N-acyltransferase activity)","00600(Sphingolipid metabolism);04071(Sphingolipid signaling pathway)","K04710","EC:2.3.1.24","ceramide synthase 6 [Source:HGNC Symbol;Acc:HGNC:23826]",{"v":1.526657,"d":"1.53"},{"v":0.642033,"d":"0.64"},{"v":2.772858,"d":"2.77"},{"v":0.156782,"d":"0.16"},0,{"v":0.001628,"d":"0.00"},{"v":31.194672053532,"d":"31.19"},{"v":4.96322773748985,"d":"4.96"},{"v":0.00448678070877695,"d":"0.00"},{"v":0.216085022635194,"d":"0.22"},"up","yes"]
[177955,0,"chr7","+",32957440,33006928,"ENST00000242209",10,3424,"ENSG00000122642","FKBP9","GO:0000413(protein peptidyl-prolyl isomerization);GO:0003755(peptidyl-prolyl cis-trans isomerase activity);GO:0005509(calcium ion binding);GO:0005783(endoplasmic reticulum);GO:0006457(protein folding);GO:0016853(isomerase activity);GO:0046872(metal ion binding)","NA","K09575","EC:5.2.1.8","FKBP prolyl isomerase 9 [Source:HGNC Symbol;Acc:HGNC:3725]",{"v":3.648289,"d":"3.65"},{"v":3.552073,"d":"3.55"},{"v":8.014419,"d":"8.01"},{"v":39.201984,"d":"39.20"},{"v":16.41227,"d":"16.41"},{"v":12.25403,"d":"12.25"},{"v":0.224181018043715,"d":"0.22"},{"v":-2.15726396809795,"d":"-2.16"},{"v":0.00449061910513547,"d":"0.00"},{"v":0.216085022635194,"d":"0.22"},"down","yes"]
[415,0,"chr1","-",1386502,1391754,"ENST00000482365",7,2620,"ENSG00000221978","CCNL2","GO:0000079(regulation of cyclin-dependent protein serine/threonine kinase activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0006357(regulation of transcription by RNA polymerase II);GO:0016538(cyclin-dependent protein serine/threonine kinase regulator activity);GO:0016607(nuclear speck);GO:0043231(intracellular membrane-bounded organelle)","NA","NA","NA","cyclin L2 [Source:HGNC Symbol;Acc:HGNC:20570]",0,{"v":0.021939,"d":"0.02"},{"v":0.003036,"d":"0.00"},{"v":0.606808,"d":"0.61"},{"v":1.410033,"d":"1.41"},0,{"v":0.0123832270367372,"d":"0.01"},{"v":-6.33546886365371,"d":"-6.34"},{"v":0.00453980561629623,"d":"0.00"},{"v":0.218162881005347,"d":"0.22"},"down","yes"]
[31647,0,"chr11","+",63681500,63750423,"ENST00000543123",2,712,"ENSG00000133318","RTN3","GO:0000139(Golgi membrane);GO:0005515(protein binding);GO:0005615(extracellular space);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005794(Golgi apparatus);GO:0005886(plasma membrane);GO:0006915(apoptotic process);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016032(viral process);GO:0016192(vesicle-mediated transport);GO:0045202(synapse);GO:0071786(endoplasmic reticulum tubular network organization);GO:0071787(endoplasmic reticulum tubular network formation)","05010(Alzheimer disease)","K20723","NA","reticulon 3 [Source:HGNC Symbol;Acc:HGNC:10469]",{"v":0.507331,"d":"0.51"},{"v":0.186397,"d":"0.19"},{"v":0.297269,"d":"0.30"},{"v":5.872468,"d":"5.87"},{"v":0.596829,"d":"0.60"},{"v":4.575169,"d":"4.58"},{"v":0.0897279234686403,"d":"0.09"},{"v":-3.47829916582644,"d":"-3.48"},{"v":0.00454972385578501,"d":"0.00"},{"v":0.218350683858216,"d":"0.22"},"down","yes"]
[114455,0,"chr2","+",85357191,85390970,"ENST00000410106",10,1392,"ENSG00000115459","ELMOD3","GO:0005096(GTPase activator activity);GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0005856(cytoskeleton);GO:0005929(cilium);GO:0032420(stereocilium);GO:0042995(cell projection);GO:0043547(positive regulation of GTPase activity);GO:0060091(kinocilium)","NA","NA","NA","ELMO domain containing 3 [Source:HGNC Symbol;Acc:HGNC:26158]",{"v":1.40265,"d":"1.40"},{"v":0.923094,"d":"0.92"},{"v":0.416222,"d":"0.42"},0,0,{"v":0.072365,"d":"0.07"},{"v":37.8907759275893,"d":"37.89"},{"v":5.24377477855619,"d":"5.24"},{"v":0.00455933316438616,"d":"0.00"},{"v":0.218523184514709,"d":"0.22"},"up","yes"]
[114702,0,"chr2","-",86143936,86195403,"ENST00000442664",15,2627,"ENSG00000132305","IMMT","GO:0003723(RNA binding);GO:0005515(protein binding);GO:0005739(mitochondrion);GO:0005743(mitochondrial inner membrane);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0042407(cristae formation);GO:0051560(mitochondrial calcium ion homeostasis);GO:0061617(MICOS complex)","NA","K17785","NA","inner membrane mitochondrial protein [Source:HGNC Symbol;Acc:HGNC:6047]",{"v":0.159093,"d":"0.16"},{"v":0.42646,"d":"0.43"},{"v":0.601902,"d":"0.60"},{"v":20.865698,"d":"20.87"},{"v":0.245786,"d":"0.25"},{"v":0.431973,"d":"0.43"},{"v":0.0551190554050819,"d":"0.06"},{"v":-4.18130502550032,"d":"-4.18"},{"v":0.00458278422257369,"d":"0.00"},{"v":0.219294946325247,"d":"0.22"},"down","yes"]
[11052,0,"chr1","-",150999411,151006871,"ENST00000470877",6,893,"ENSG00000143409","MINDY1","GO:0004843(thiol-dependent ubiquitin-specific protease activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0006508(proteolysis);GO:0008150(biological_process);GO:0008233(peptidase activity);GO:0008234(cysteine-type peptidase activity);GO:0016604(nuclear body);GO:0016787(hydrolase activity);GO:0016807(cysteine-type carboxypeptidase activity);GO:0036435(K48-linked polyubiquitin modification-dependent protein binding);GO:0036459(thiol-dependent ubiquitinyl hydrolase activity);GO:0071108(protein K48-linked deubiquitination);GO:1990380(Lys48-specific deubiquitinase activity)","NA","K01309","EC:3.4.19.12","MINDY lysine 48 deubiquitinase 1 [Source:HGNC Symbol;Acc:HGNC:25648]",{"v":3.071627,"d":"3.07"},{"v":0.038741,"d":"0.04"},{"v":1.599318,"d":"1.60"},{"v":0.020718,"d":"0.02"},{"v":0.103915,"d":"0.10"},{"v":0.02422,"d":"0.02"},{"v":31.639846022586,"d":"31.64"},{"v":4.98367067374383,"d":"4.98"},{"v":0.00458750782293388,"d":"0.00"},{"v":0.219294946325247,"d":"0.22"},"up","yes"]
[12982,0,"chr1","-",160288686,160343273,"ENST00000649963",32,5175,"ENSG00000122218","COPA","GO:0000139(Golgi membrane);GO:0005179(hormone activity);GO:0005198(structural molecule activity);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0005615(extracellular space);GO:0005737(cytoplasm);GO:0005789(endoplasmic reticulum membrane);GO:0005794(Golgi apparatus);GO:0005829(cytosol);GO:0006886(intracellular protein transport);GO:0006888(endoplasmic reticulum to Golgi vesicle-mediated transport);GO:0006890(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum);GO:0006891(intra-Golgi vesicle-mediated transport);GO:0010469(regulation of signaling receptor activity);GO:0015031(protein transport);GO:0016020(membrane);GO:0016192(vesicle-mediated transport);GO:0030117(membrane coat);GO:0030126(COPI vesicle coat);GO:0030133(transport vesicle);GO:0030157(pancreatic juice secretion);GO:0030663(COPI-coated vesicle membrane);GO:0031410(cytoplasmic vesicle);GO:0070062(extracellular exosome)","NA","NA","NA","coatomer protein complex subunit alpha [Source:HGNC Symbol;Acc:HGNC:2230]",{"v":0.678848,"d":"0.68"},{"v":0.371038,"d":"0.37"},{"v":2.129739,"d":"2.13"},{"v":12.554126,"d":"12.55"},{"v":4.856511,"d":"4.86"},{"v":2.597492,"d":"2.60"},{"v":0.158916658324224,"d":"0.16"},{"v":-2.65365773280578,"d":"-2.65"},{"v":0.00468629498842632,"d":"0.00"},{"v":0.223722860616989,"d":"0.22"},"down","yes"]
[51325,0,"chr13","+",41457550,41470871,"ENST00000379359",5,958,"ENSG00000102760","RGCC","GO:0001100(negative regulation of exit from mitosis);GO:0001937(negative regulation of endothelial cell proliferation);GO:0003331(positive regulation of extracellular matrix constituent secretion);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005730(nucleolus);GO:0005737(cytoplasm);GO:0005813(centrosome);GO:0005815(microtubule organizing center);GO:0005829(cytosol);GO:0005856(cytoskeleton);GO:0006956(complement activation);GO:0006977(DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest);GO:0007049(cell cycle);GO:0008285(negative regulation of cell population proliferation);GO:0010628(positive regulation of gene expression);GO:0010718(positive regulation of epithelial to mesenchymal transition);GO:0016525(negative regulation of angiogenesis);GO:0019901(protein kinase binding);GO:0030295(protein kinase activator activity);GO:0032147(activation of protein kinase activity);GO:0032967(positive regulation of collagen biosynthetic process);GO:0043537(negative regulation of blood vessel endothelial cell migration);GO:0045737(positive regulation of cyclin-dependent protein serine/threonine kinase activity);GO:0045840(positive regulation of mitotic nuclear division);GO:0045944(positive regulation of transcription by RNA polymerase II);GO:0050710(negative regulation of cytokine secretion);GO:0050715(positive regulation of cytokine secretion);GO:0051091(positive regulation of DNA-binding transcription factor activity);GO:0051496(positive regulation of stress fiber assembly);GO:0051726(regulation of cell cycle);GO:0070412(R-SMAD binding);GO:0071158(positive regulation of cell cycle arrest);GO:0071456(cellular response to hypoxia);GO:0071850(mitotic cell cycle arrest);GO:0072537(fibroblast activation);GO:0090272(negative regulation of fibroblast growth factor production);GO:1900087(positive regulation of G1/S transition of mitotic cell cycle);GO:1901203(positive regulation of extracellular matrix assembly);GO:1901991(negative regulation of mitotic cell cycle phase transition);GO:2000048(negative regulation of cell-cell adhesion mediated by cadherin);GO:2000353(positive regulation of endothelial cell apoptotic process);GO:2000573(positive regulation of DNA biosynthetic process)","NA","NA","NA","regulator of cell cycle [Source:HGNC Symbol;Acc:HGNC:20369]",{"v":34.726631,"d":"34.73"},{"v":35.973038,"d":"35.97"},{"v":31.564812,"d":"31.56"},{"v":123.432121,"d":"123.43"},{"v":121.129303,"d":"121.13"},{"v":114.760765,"d":"114.76"},{"v":0.284603857291986,"d":"0.28"},{"v":-1.81297287976117,"d":"-1.81"},{"v":0.0047449316665808,"d":"0.00"},{"v":0.226224891662573,"d":"0.23"},"down","yes"]
[80448,0,"chr17","+",6070614,6124425,"ENST00000317744",9,5819,"ENSG00000179314","WSCD1","GO:0008146(sulfotransferase activity);GO:0016020(membrane);GO:0016021(integral component of membrane)","NA","NA","NA","WSC domain containing 1 [Source:HGNC Symbol;Acc:HGNC:29060]",{"v":0.561744,"d":"0.56"},{"v":0.343825,"d":"0.34"},{"v":0.279923,"d":"0.28"},{"v":2.77476,"d":"2.77"},{"v":2.500869,"d":"2.50"},{"v":2.105591,"d":"2.11"},{"v":0.160609221781765,"d":"0.16"},{"v":-2.63837336369549,"d":"-2.64"},{"v":0.00476977390141339,"d":"0.00"},{"v":0.227111252737023,"d":"0.23"},"down","yes"]
[37451,0,"chr11","-",122089103,122102178,"ENST00000531381",2,3370,"ENSG00000255248","MIR100HG","NA","NA","NA","NA","mir-100-let-7a-2-mir-125b-1 cluster host gene [Source:HGNC Symbol;Acc:HGNC:39522]",{"v":0.337308,"d":"0.34"},{"v":0.370578,"d":"0.37"},{"v":0.259991,"d":"0.26"},{"v":0.246946,"d":"0.25"},{"v":3.036257,"d":"3.04"},{"v":6.837292,"d":"6.84"},{"v":0.0956353419472071,"d":"0.10"},{"v":-3.38631232648929,"d":"-3.39"},{"v":0.00481898307223016,"d":"0.00"},{"v":0.228966566634214,"d":"0.23"},"down","yes"]
[90752,0,"chr17","-",76679569,76711016,"ENST00000449428",4,1881,"ENSG00000182534","MXRA7","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0062023(collagen-containing extracellular matrix)","NA","NA","NA","matrix remodeling associated 7 [Source:HGNC Symbol;Acc:HGNC:7541]",{"v":1.604686,"d":"1.60"},{"v":18.356321,"d":"18.36"},{"v":3.488166,"d":"3.49"},{"v":55.742886,"d":"55.74"},{"v":21.308155,"d":"21.31"},{"v":64.169464,"d":"64.17"},{"v":0.166046517111662,"d":"0.17"},{"v":-2.59034063280212,"d":"-2.59"},{"v":0.0048213438886643,"d":"0.00"},{"v":0.228966566634214,"d":"0.23"},"down","yes"]
[133641,0,"chr22","+",30969272,30978578,"ENST00000569384",3,4214,"ENSG00000253352","TUG1","NA","NA","NA","NA","taurine up-regulated 1 [Source:HGNC Symbol;Acc:HGNC:26066]",0,{"v":0.234581,"d":"0.23"},0,{"v":0.166292,"d":"0.17"},{"v":22.869781,"d":"22.87"},{"v":0.110987,"d":"0.11"},{"v":0.0101343755967281,"d":"0.01"},{"v":-6.62459898614548,"d":"-6.62"},{"v":0.00494055040690029,"d":"0.00"},{"v":0.234321405068783,"d":"0.23"},"down","yes"]
[19498,0,"chr10","+",17229291,17231093,"ENST00000485947",2,1139,"ENSG00000026025","VIM","GO:0003725(double-stranded RNA binding);GO:0005198(structural molecule activity);GO:0005200(structural constituent of cytoskeleton);GO:0005212(structural constituent of eye lens);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005777(peroxisome);GO:0005829(cytosol);GO:0005844(polysome);GO:0005856(cytoskeleton);GO:0005882(intermediate filament);GO:0005886(plasma membrane);GO:0005925(focal adhesion);GO:0010628(positive regulation of gene expression);GO:0010977(negative regulation of neuron projection development);GO:0014002(astrocyte development);GO:0016032(viral process);GO:0016363(nuclear matrix);GO:0019221(cytokine-mediated signaling pathway);GO:0019904(protein domain specific binding);GO:0030049(muscle filament sliding);GO:0031252(cell leading edge);GO:0032967(positive regulation of collagen biosynthetic process);GO:0042802(identical protein binding);GO:0042995(cell projection);GO:0043005(neuron projection);GO:0043488(regulation of mRNA stability);GO:0045103(intermediate filament-based process);GO:0045109(intermediate filament organization);GO:0045335(phagocytic vesicle);GO:0045727(positive regulation of translation);GO:0060020(Bergmann glial cell differentiation);GO:0060395(SMAD protein signal transduction);GO:0070062(extracellular exosome);GO:0070307(lens fiber cell development);GO:0071222(cellular response to lipopolysaccharide);GO:0071225(cellular response to muramyl dipeptide);GO:0071346(cellular response to interferon-gamma);GO:0097110(scaffold protein binding);GO:1990254(keratin filament binding);GO:1990904(ribonucleoprotein complex)","05169(Epstein-Barr virus infection);05206(MicroRNAs in cancer)","K07606","NA","vimentin [Source:HGNC Symbol;Acc:HGNC:12692]",{"v":492.327271,"d":"492.33"},{"v":53.457226,"d":"53.46"},{"v":514.597412,"d":"514.60"},{"v":88.368904,"d":"88.37"},{"v":62.046131,"d":"62.05"},{"v":60.715611,"d":"60.72"},{"v":5.02239693331872,"d":"5.02"},{"v":2.3283760531217,"d":"2.33"},{"v":0.00496759753899434,"d":"0.00"},{"v":0.235297025543239,"d":"0.24"},"up","yes"]
[120719,0,"chr2","+",200306376,200478102,"ENST00000451764",14,2250,"ENSG00000196141","SPATS2L","GO:0003723(RNA binding);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005730(nucleolus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0032991(protein-containing complex)","NA","NA","NA","spermatogenesis associated serine rich 2 like [Source:HGNC Symbol;Acc:HGNC:24574]",{"v":0.568118,"d":"0.57"},{"v":0.614339,"d":"0.61"},{"v":0.81863,"d":"0.82"},{"v":0.352571,"d":"0.35"},{"v":22.796604,"d":"22.80"},{"v":1.90749,"d":"1.91"},{"v":0.0798624637396876,"d":"0.08"},{"v":-3.64633861028808,"d":"-3.65"},{"v":0.00501820770174628,"d":"0.01"},{"v":0.237384747141201,"d":"0.24"},"down","yes"]
[193339,0,"chr8","+",143018552,143022255,"ENST00000519546",4,971,"ENSG00000160932","LY6E","GO:0005576(extracellular region);GO:0005886(plasma membrane);GO:0007166(cell surface receptor signaling pathway);GO:0016020(membrane);GO:0030550(acetylcholine receptor inhibitor activity);GO:0031225(anchored component of membrane);GO:2000272(negative regulation of signaling receptor activity)","NA","K06846","NA","lymphocyte antigen 6 family member E [Source:HGNC Symbol;Acc:HGNC:6727]",{"v":0.638061,"d":"0.64"},{"v":0.742184,"d":"0.74"},{"v":0.3207,"d":"0.32"},{"v":22.176537,"d":"22.18"},{"v":0.937294,"d":"0.94"},{"v":1.233946,"d":"1.23"},{"v":0.0698603819149485,"d":"0.07"},{"v":-3.83938166004944,"d":"-3.84"},{"v":0.00503730958025637,"d":"0.01"},{"v":0.237978487712242,"d":"0.24"},"down","yes"]
[142093,0,"chr3","+",93980149,94054154,"ENST00000394222",10,2453,"ENSG00000169379","ARL13B","GO:0000166(nucleotide binding);GO:0001947(heart looping);GO:0005515(protein binding);GO:0005525(GTP binding);GO:0005886(plasma membrane);GO:0005929(cilium);GO:0005930(axoneme);GO:0007224(smoothened signaling pathway);GO:0007368(determination of left/right symmetry);GO:0009953(dorsal/ventral pattern formation);GO:0010226(response to lithium ion);GO:0016020(membrane);GO:0021532(neural tube patterning);GO:0021830(interneuron migration from the subpallium to the cortex);GO:0021943(formation of radial glial scaffolds);GO:0031514(motile cilium);GO:0042995(cell projection);GO:0060170(ciliary membrane);GO:0060271(cilium assembly);GO:0070986(left/right axis specification);GO:0097500(receptor localization to non-motile cilium);GO:0097730(non-motile cilium);GO:1905515(non-motile cilium assembly)","NA","K07962","NA","ADP ribosylation factor like GTPase 13B [Source:HGNC Symbol;Acc:HGNC:25419]",{"v":0.2032,"d":"0.20"},{"v":0.158846,"d":"0.16"},{"v":0.178184,"d":"0.18"},{"v":2.800319,"d":"2.80"},{"v":1.835401,"d":"1.84"},{"v":0.412186,"d":"0.41"},{"v":0.107020614092259,"d":"0.11"},{"v":-3.22403938252004,"d":"-3.22"},{"v":0.00506061267377681,"d":"0.01"},{"v":0.238742805658057,"d":"0.24"},"down","yes"]
[86133,0,"chr17","-",43753738,43758791,"ENST00000301691",2,2296,"ENSG00000167941","SOST","GO:0001503(ossification);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0005615(extracellular space);GO:0005794(Golgi apparatus);GO:0008134(transcription factor binding);GO:0008201(heparin binding);GO:0009612(response to mechanical stimulus);GO:0016055(Wnt signaling pathway);GO:0030279(negative regulation of ossification);GO:0030514(negative regulation of BMP signaling pathway);GO:0031333(negative regulation of protein complex assembly);GO:0032991(protein-containing complex);GO:0045893(positive regulation of transcription, DNA-templated);GO:0062023(collagen-containing extracellular matrix);GO:0071374(cellular response to parathyroid hormone stimulus);GO:0090090(negative regulation of canonical Wnt signaling pathway)","04310(Wnt signaling pathway);04928(Parathyroid hormone synthesis, secretion and action)","K16834","NA","sclerostin [Source:HGNC Symbol;Acc:HGNC:13771]",{"v":0.027433,"d":"0.03"},{"v":0.038267,"d":"0.04"},{"v":0.056308,"d":"0.06"},{"v":0.539542,"d":"0.54"},{"v":0.561093,"d":"0.56"},{"v":0.518566,"d":"0.52"},{"v":0.0753507439780484,"d":"0.08"},{"v":-3.73023443338438,"d":"-3.73"},{"v":0.00506663097061278,"d":"0.01"},{"v":0.238742805658057,"d":"0.24"},"down","yes"]
[31492,0,"chr11","-",62832912,62839661,"ENST00000278856",11,1289,"ENSG00000133316","WDR74","GO:0000176(nuclear exosome (RNase complex));GO:0001825(blastocyst formation);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005730(nucleolus);GO:0006364(rRNA processing);GO:0016070(RNA metabolic process);GO:0030687(preribosome, large subunit precursor);GO:0042273(ribosomal large subunit biogenesis)","NA","K14841","NA","WD repeat domain 74 [Source:HGNC Symbol;Acc:HGNC:25529]",{"v":3.87107,"d":"3.87"},{"v":3.295043,"d":"3.30"},{"v":0.748154,"d":"0.75"},{"v":0.2299,"d":"0.23"},{"v":0.111112,"d":"0.11"},{"v":0.436949,"d":"0.44"},{"v":10.1730896535945,"d":"10.17"},{"v":3.34668599935032,"d":"3.35"},{"v":0.00508842930846822,"d":"0.01"},{"v":0.239459374063019,"d":"0.24"},"up","yes"]
[198194,0,"chr9","-",107484852,107489769,"ENST00000374672",5,2936,"ENSG00000136826","KLF4","GO:0000122(negative regulation of transcription by RNA polymerase II);GO:0000785(chromatin);GO:0000790(nuclear chromatin);GO:0000978(RNA polymerase II proximal promoter sequence-specific DNA binding);GO:0000981(DNA-binding transcription factor activity, RNA polymerase II-specific);GO:0000987(proximal promoter sequence-specific DNA binding);GO:0001010(RNA polymerase II sequence-specific DNA-binding transcription factor recruiting activity);GO:0001085(RNA polymerase II transcription factor binding);GO:0001221(transcription cofactor binding);GO:0001228(DNA-binding transcription activator activity, RNA polymerase II-specific);GO:0003676(nucleic acid binding);GO:0003677(DNA binding);GO:0003690(double-stranded DNA binding);GO:0003700(DNA-binding transcription factor activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005667(transcription factor complex);GO:0005719(nuclear euchromatin);GO:0005737(cytoplasm);GO:0006351(transcription, DNA-templated);GO:0006357(regulation of transcription by RNA polymerase II);GO:0006366(transcription by RNA polymerase II);GO:0007500(mesodermal cell fate determination);GO:0008013(beta-catenin binding);GO:0008134(transcription factor binding);GO:0008270(zinc ion binding);GO:0008285(negative regulation of cell population proliferation);GO:0009913(epidermal cell differentiation);GO:0010033(response to organic substance);GO:0010628(positive regulation of gene expression);GO:0010629(negative regulation of gene expression);GO:0014067(negative regulation of phosphatidylinositol 3-kinase signaling);GO:0014740(negative regulation of muscle hyperplasia);GO:0016525(negative regulation of angiogenesis);GO:0019827(stem cell population maintenance);GO:0030154(cell differentiation);GO:0030336(negative regulation of cell migration);GO:0031077(post-embryonic camera-type eye development);GO:0032088(negative regulation of NF-kappaB transcription factor activity);GO:0032270(positive regulation of cellular protein metabolic process);GO:0032526(response to retinoic acid);GO:0034115(negative regulation of heterotypic cell-cell adhesion);GO:0035014(phosphatidylinositol 3-kinase regulator activity);GO:0035019(somatic stem cell population maintenance);GO:0035166(post-embryonic hemopoiesis);GO:0042127(regulation of cell population proliferation);GO:0042826(histone deacetylase binding);GO:0043154(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process);GO:0043433(negative regulation of DNA-binding transcription factor activity);GO:0043551(regulation of phosphatidylinositol 3-kinase activity);GO:0043565(sequence-specific DNA binding);GO:0044212(transcription regulatory region DNA binding);GO:0044798(nuclear transcription factor complex);GO:0045415(negative regulation of interleukin-8 biosynthetic process);GO:0045429(positive regulation of nitric oxide biosynthetic process);GO:0045444(fat cell differentiation);GO:0045595(regulation of cell differentiation);GO:0045892(negative regulation of transcription, DNA-templated);GO:0045893(positive regulation of transcription, DNA-templated);GO:0045944(positive regulation of transcription by RNA polymerase II);GO:0046872(metal ion binding);GO:0046985(positive regulation of hemoglobin biosynthetic process);GO:0048662(negative regulation of smooth muscle cell proliferation);GO:0048679(regulation of axon regeneration);GO:0048730(epidermis morphogenesis);GO:0050728(negative regulation of inflammatory response);GO:0051247(positive regulation of protein metabolic process);GO:0051898(negative regulation of protein kinase B signaling);GO:0051973(positive regulation of telomerase activity);GO:0060070(canonical Wnt signaling pathway);GO:0060761(negative regulation of response to cytokine stimulus);GO:0061614(pri-miRNA transcription by RNA polymerase II);GO:0070301(cellular response to hydrogen peroxide);GO:0070373(negative regulation of ERK1 and ERK2 cascade);GO:0071300(cellular response to retinoic acid);GO:0071363(cellular response to growth factor stimulus);GO:0071407(cellular response to organic cyclic compound);GO:0071409(cellular response to cycloheximide);GO:0071499(cellular response to laminar fluid shear stress);GO:0090051(negative regulation of cell migration involved in sprouting angiogenesis);GO:1901653(cellular response to peptide);GO:1903672(positive regulation of sprouting angiogenesis);GO:1904798(positive regulation of core promoter binding);GO:1904998(negative regulation of leukocyte adhesion to arterial endothelial cell);GO:1990830(cellular response to leukemia inhibitory factor);GO:1990841(promoter-specific chromatin binding);GO:2000134(negative regulation of G1/S transition of mitotic cell cycle);GO:2000342(negative regulation of chemokine (C-X-C motif) ligand 2 production)","04550(Signaling pathways regulating pluripotency of stem cells)","K17846","NA","Kruppel like factor 4 [Source:HGNC Symbol;Acc:HGNC:6348]",{"v":0.29675,"d":"0.30"},{"v":0.567321,"d":"0.57"},{"v":0.573248,"d":"0.57"},{"v":6.303395,"d":"6.30"},{"v":0.639282,"d":"0.64"},{"v":5.292967,"d":"5.29"},{"v":0.117469828314717,"d":"0.12"},{"v":-3.0896378413339,"d":"-3.09"},{"v":0.00511835021597871,"d":"0.01"},{"v":0.240546044257611,"d":"0.24"},"down","yes"]
[116606,0,"chr2","+",113890063,113931369,"ENST00000443297",4,566,"ENSG00000115091","ACTR3","GO:0000166(nucleotide binding);GO:0003779(actin binding);GO:0005200(structural constituent of cytoskeleton);GO:0005515(protein binding);GO:0005524(ATP binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005856(cytoskeleton);GO:0005885(Arp2/3 protein complex);GO:0005903(brush border);GO:0005911(cell-cell junction);GO:0005925(focal adhesion);GO:0007015(actin filament organization);GO:0007163(establishment or maintenance of cell polarity);GO:0008356(asymmetric cell division);GO:0015629(actin cytoskeleton);GO:0016020(membrane);GO:0016344(meiotic chromosome movement towards spindle pole);GO:0030027(lamellipodium);GO:0030030(cell projection organization);GO:0033206(meiotic cytokinesis);GO:0034314(Arp2/3 complex-mediated actin nucleation);GO:0035861(site of double-strand break);GO:0038096(Fc-gamma receptor signaling pathway involved in phagocytosis);GO:0042995(cell projection);GO:0045944(positive regulation of transcription by RNA polymerase II);GO:0048013(ephrin receptor signaling pathway);GO:0051015(actin filament binding);GO:0051321(meiotic cell cycle);GO:0051653(spindle localization);GO:0060271(cilium assembly);GO:0061024(membrane organization);GO:0070062(extracellular exosome);GO:0070358(actin polymerization-dependent cell motility);GO:0071346(cellular response to interferon-gamma)","04530(Tight junction)","K18584","NA","ARP3 actin related protein 3 homolog [Source:HGNC Symbol;Acc:HGNC:170]",{"v":0.287697,"d":"0.29"},0,0,{"v":14.957023,"d":"14.96"},{"v":15.008657,"d":"15.01"},0,{"v":0.00960088341062175,"d":"0.01"},{"v":-6.70261712534016,"d":"-6.70"},{"v":0.00512476295775917,"d":"0.01"},{"v":0.240546044257611,"d":"0.24"},"down","yes"]
[28998,0,"chr11","+",34052329,34099058,"ENST00000530820",17,3454,"ENSG00000135387","CAPRIN1","GO:0000932(P-body);GO:0003723(RNA binding);GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0010494(cytoplasmic stress granule);GO:0016020(membrane);GO:0017148(negative regulation of translation);GO:0030154(cell differentiation);GO:0030425(dendrite);GO:0042995(cell projection);GO:0045202(synapse);GO:0050775(positive regulation of dendrite morphogenesis);GO:0061003(positive regulation of dendritic spine morphogenesis)","NA","K18743","NA","cell cycle associated protein 1 [Source:HGNC Symbol;Acc:HGNC:6743]",{"v":0.289383,"d":"0.29"},{"v":0.168023,"d":"0.17"},{"v":0.302181,"d":"0.30"},{"v":3.720406,"d":"3.72"},{"v":0.317478,"d":"0.32"},{"v":3.142598,"d":"3.14"},{"v":0.105784959839743,"d":"0.11"},{"v":-3.24079357052658,"d":"-3.24"},{"v":0.00513795500163412,"d":"0.01"},{"v":0.240854071237894,"d":"0.24"},"down","yes"]
[17036,0,"chr1","+",226062714,226067269,"ENST00000366814",3,1863,"ENSG00000163041","H3F3A","GO:0000183(chromatin silencing at rDNA);GO:0000228(nuclear chromosome);GO:0000784(nuclear chromosome, telomeric region);GO:0000786(nucleosome);GO:0000788(nuclear nucleosome);GO:0000979(RNA polymerase II core promoter sequence-specific DNA binding);GO:0000980(RNA polymerase II distal enhancer sequence-specific DNA binding);GO:0001649(osteoblast differentiation);GO:0001740(Barr body);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005694(chromosome);GO:0006334(nucleosome assembly);GO:0006336(DNA replication-independent nucleosome assembly);GO:0006997(nucleus organization);GO:0007283(spermatogenesis);GO:0007286(spermatid development);GO:0007338(single fertilization);GO:0007566(embryo implantation);GO:0007596(blood coagulation);GO:0008283(cell population proliferation);GO:0008584(male gonad development);GO:0030307(positive regulation of cell growth);GO:0031492(nucleosomal DNA binding);GO:0031508(pericentric heterochromatin assembly);GO:0031509(telomeric heterochromatin assembly);GO:0032200(telomere organization);GO:0032991(protein-containing complex);GO:0035264(multicellular organism growth);GO:0042692(muscle cell differentiation);GO:0044267(cellular protein metabolic process);GO:0045652(regulation of megakaryocyte differentiation);GO:0045814(negative regulation of gene expression, epigenetic);GO:0046982(protein heterodimerization activity);GO:0048477(oogenesis);GO:0060964(regulation of gene silencing by miRNA);GO:0070062(extracellular exosome);GO:0090230(regulation of centromere complex assembly);GO:1902340(negative regulation of chromosome condensation)","05034(Alcoholism);05202(Transcriptional misregulation in cancer);05322(Systemic lupus erythematosus)","K11253","NA","H3 histone family member 3A [Source:HGNC Symbol;Acc:HGNC:4764]",{"v":0.488565,"d":"0.49"},{"v":2.465285,"d":"2.47"},{"v":3.422594,"d":"3.42"},{"v":0.296374,"d":"0.30"},{"v":0.078485,"d":"0.08"},{"v":0.215435,"d":"0.22"},{"v":10.802149437399,"d":"10.80"},{"v":3.43324650673308,"d":"3.43"},{"v":0.00516861008553525,"d":"0.01"},{"v":0.241978871659144,"d":"0.24"},"up","yes"]
[207245,0,"chrX","-",153947559,153971184,"ENST00000369984",26,8375,"ENSG00000172534","HCFC1","GO:0000122(negative regulation of transcription by RNA polymerase II);GO:0000123(histone acetyltransferase complex);GO:0001228(DNA-binding transcription activator activity, RNA polymerase II-specific);GO:0001835(blastocyst hatching);GO:0003682(chromatin binding);GO:0003713(transcription coactivator activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005671(Ada2/Gcn5/Ada3 transcription activator complex);GO:0005737(cytoplasm);GO:0006325(chromatin organization);GO:0006355(regulation of transcription, DNA-templated);GO:0007005(mitochondrion organization);GO:0007049(cell cycle);GO:0010628(positive regulation of gene expression);GO:0016020(membrane);GO:0016032(viral process);GO:0016579(protein deubiquitination);GO:0019046(release from viral latency);GO:0030424(axon);GO:0030425(dendrite);GO:0030674(protein binding, bridging);GO:0032991(protein-containing complex);GO:0033613(activating transcription factor binding);GO:0042802(identical protein binding);GO:0043025(neuronal cell body);GO:0043254(regulation of protein complex assembly);GO:0043981(histone H4-K5 acetylation);GO:0043982(histone H4-K8 acetylation);GO:0043984(histone H4-K16 acetylation);GO:0043995(histone acetyltransferase activity (H4-K5 specific));GO:0043996(histone acetyltransferase activity (H4-K8 specific));GO:0045296(cadherin binding);GO:0045787(positive regulation of cell cycle);GO:0045893(positive regulation of transcription, DNA-templated);GO:0045944(positive regulation of transcription by RNA polymerase II);GO:0046972(histone acetyltransferase activity (H4-K16 specific));GO:0048188(Set1C/COMPASS complex);GO:0050821(protein stabilization);GO:0070461(SAGA-type complex);GO:0071339(MLL1 complex);GO:0071407(cellular response to organic cyclic compound);GO:1990837(sequence-specific double-stranded DNA binding)","05168(Herpes simplex virus 1 infection)","K14966","NA","host cell factor C1 [Source:HGNC Symbol;Acc:HGNC:4839]",{"v":0.052151,"d":"0.05"},{"v":0.401391,"d":"0.40"},{"v":0.042479,"d":"0.04"},{"v":3.334243,"d":"3.33"},{"v":0.079161,"d":"0.08"},{"v":3.222536,"d":"3.22"},{"v":0.0747476619740383,"d":"0.07"},{"v":-3.7418277356976,"d":"-3.74"},{"v":0.00521038388135601,"d":"0.01"},{"v":0.243620651749889,"d":"0.24"},"down","yes"]
[12946,0,"chr1","-",160215715,160262451,"ENST00000368073",14,4106,"ENSG00000132716","DCAF8","GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0005739(mitochondrion);GO:0005829(cytosol);GO:0016567(protein ubiquitination);GO:0043687(post-translational protein modification);GO:0080008(Cul4-RING E3 ubiquitin ligase complex)","NA","K11804","NA","DDB1 and CUL4 associated factor 8 [Source:HGNC Symbol;Acc:HGNC:24891]",{"v":1.360929,"d":"1.36"},{"v":1.163508,"d":"1.16"},{"v":1.766046,"d":"1.77"},{"v":1.68104,"d":"1.68"},{"v":11.308205,"d":"11.31"},{"v":10.87252,"d":"10.87"},{"v":0.179805768768572,"d":"0.18"},{"v":-2.47548878682532,"d":"-2.48"},{"v":0.00522246730812953,"d":"0.01"},{"v":0.243871770314069,"d":"0.24"},"down","yes"]
[37453,0,"chr11","-",122089110,122100447,"ENST00000524376",2,2684,"ENSG00000255248","MIR100HG","NA","NA","NA","NA","mir-100-let-7a-2-mir-125b-1 cluster host gene [Source:HGNC Symbol;Acc:HGNC:39522]",{"v":0.870688,"d":"0.87"},{"v":1.11567,"d":"1.12"},{"v":0.822288,"d":"0.82"},{"v":1.288268,"d":"1.29"},{"v":1.771984,"d":"1.77"},{"v":22.432287,"d":"22.43"},{"v":0.110175216364286,"d":"0.11"},{"v":-3.18212836507595,"d":"-3.18"},{"v":0.00522965143874349,"d":"0.01"},{"v":0.243893757085431,"d":"0.24"},"down","yes"]
[76429,0,"chr16","+",67562526,67639177,"ENST00000264010",12,3814,"ENSG00000102974","CTCF","GO:0000122(negative regulation of transcription by RNA polymerase II);GO:0000775(chromosome, centromeric region);GO:0000793(condensed chromosome);GO:0000978(RNA polymerase II proximal promoter sequence-specific DNA binding);GO:0000981(DNA-binding transcription factor activity, RNA polymerase II-specific);GO:0001227(DNA-binding transcription repressor activity, RNA polymerase II-specific);GO:0001228(DNA-binding transcription activator activity, RNA polymerase II-specific);GO:0003676(nucleic acid binding);GO:0003677(DNA binding);GO:0003682(chromatin binding);GO:0003700(DNA-binding transcription factor activity);GO:0003714(transcription corepressor activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005694(chromosome);GO:0005730(nucleolus);GO:0006306(DNA methylation);GO:0006325(chromatin organization);GO:0006349(regulation of gene expression by genetic imprinting);GO:0006355(regulation of transcription, DNA-templated);GO:0007059(chromosome segregation);GO:0008270(zinc ion binding);GO:0008285(negative regulation of cell population proliferation);GO:0010216(maintenance of DNA methylation);GO:0010628(positive regulation of gene expression);GO:0010629(negative regulation of gene expression);GO:0016584(nucleosome positioning);GO:0031060(regulation of histone methylation);GO:0035065(regulation of histone acetylation);GO:0040029(regulation of gene expression, epigenetic);GO:0040030(regulation of molecular function, epigenetic);GO:0043035(chromatin insulator sequence binding);GO:0043565(sequence-specific DNA binding);GO:0044212(transcription regulatory region DNA binding);GO:0045892(negative regulation of transcription, DNA-templated);GO:0045893(positive regulation of transcription, DNA-templated);GO:0045944(positive regulation of transcription by RNA polymerase II);GO:0046872(metal ion binding);GO:0070602(regulation of centromeric sister chromatid cohesion);GO:0071459(protein localization to chromosome, centromeric region)","NA","K23195","NA","CCCTC-binding factor [Source:HGNC Symbol;Acc:HGNC:13723]",{"v":0.092026,"d":"0.09"},{"v":0.029275,"d":"0.03"},{"v":0.133552,"d":"0.13"},{"v":1.505135,"d":"1.51"},{"v":2.485438,"d":"2.49"},{"v":0.036821,"d":"0.04"},{"v":0.06327987775718,"d":"0.06"},{"v":-3.98210937693116,"d":"-3.98"},{"v":0.00533600217358287,"d":"0.01"},{"v":0.248534562777264,"d":"0.25"},"down","yes"]
[69605,0,"chr16","+",1308880,1327018,"ENST00000355803",7,3253,"ENSG00000103275","UBE2I","GO:0000122(negative regulation of transcription by RNA polymerase II);GO:0000166(nucleotide binding);GO:0000795(synaptonemal complex);GO:0003723(RNA binding);GO:0005515(protein binding);GO:0005524(ATP binding);GO:0005634(nucleus);GO:0005635(nuclear envelope);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0006464(cellular protein modification process);GO:0006511(ubiquitin-dependent protein catabolic process);GO:0007049(cell cycle);GO:0007059(chromosome segregation);GO:0008134(transcription factor binding);GO:0016032(viral process);GO:0016567(protein ubiquitination);GO:0016604(nuclear body);GO:0016605(PML body);GO:0016740(transferase activity);GO:0016925(protein sumoylation);GO:0019789(SUMO transferase activity);GO:0019899(enzyme binding);GO:0043123(positive regulation of I-kappaB kinase/NF-kappaB signaling);GO:0043398(HLH domain binding);GO:0044388(small protein activating enzyme binding);GO:0045892(negative regulation of transcription, DNA-templated);GO:0051301(cell division);GO:0061656(SUMO conjugating enzyme activity);GO:0071535(RING-like zinc finger domain binding);GO:1903755(positive regulation of SUMO transferase activity);GO:1990234(transferase complex);GO:1990356(sumoylated E2 ligase complex)","03013(RNA transport);04064(NF-kappa B signaling pathway);04120(Ubiquitin mediated proteolysis);05206(MicroRNAs in cancer)","K10577","NA","ubiquitin conjugating enzyme E2 I [Source:HGNC Symbol;Acc:HGNC:12485]",{"v":1.480753,"d":"1.48"},{"v":0.93042,"d":"0.93"},0,{"v":0.028892,"d":"0.03"},0,0,{"v":83.4546933407171,"d":"83.45"},{"v":6.3829212813114,"d":"6.38"},{"v":0.00536333179120536,"d":"0.01"},{"v":0.249487636330974,"d":"0.25"},"up","yes"]
[101433,0,"chr19","+",19865907,19893648,"ENST00000355650",2,2268,"ENSG00000256771","ZNF253","GO:0000981(DNA-binding transcription factor activity, RNA polymerase II-specific);GO:0003676(nucleic acid binding);GO:0003677(DNA binding);GO:0005622(intracellular);GO:0005634(nucleus);GO:0006355(regulation of transcription, DNA-templated);GO:0006357(regulation of transcription by RNA polymerase II);GO:0008270(zinc ion binding);GO:0045892(negative regulation of transcription, DNA-templated);GO:0046872(metal ion binding)","05168(Herpes simplex virus 1 infection)","K09228","NA","zinc finger protein 253 [Source:HGNC Symbol;Acc:HGNC:13497]",{"v":0.069727,"d":"0.07"},0,{"v":0.003292,"d":"0.00"},{"v":0.368015,"d":"0.37"},{"v":0.883543,"d":"0.88"},{"v":0.665647,"d":"0.67"},{"v":0.0380861723185575,"d":"0.04"},{"v":-4.71458888623989,"d":"-4.71"},{"v":0.00537691988450416,"d":"0.01"},{"v":0.24979987136066,"d":"0.25"},"down","yes"]
[178480,0,"chr7","-",43875913,43906626,"ENST00000443736",6,3596,"ENSG00000106608","URGCP","GO:0005525(GTP binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0007049(cell cycle)","NA","NA","NA","upregulator of cell proliferation [Source:HGNC Symbol;Acc:HGNC:30890]",0,0,{"v":0.057776,"d":"0.06"},0,{"v":2.186734,"d":"2.19"},{"v":3.893565,"d":"3.89"},{"v":0.00950216428501296,"d":"0.01"},{"v":-6.71752813462512,"d":"-6.72"},{"v":0.00539757412438222,"d":"0.01"},{"v":0.250439167227083,"d":"0.25"},"down","yes"]
[89506,0,"chr17","+",68515400,68551319,"ENST00000588188",10,1209,"ENSG00000108946","PRKAR1A","GO:0000166(nucleotide binding);GO:0001707(mesoderm formation);GO:0001772(immunological synapse);GO:0001932(regulation of protein phosphorylation);GO:0003091(renal water homeostasis);GO:0004862(cAMP-dependent protein kinase inhibitor activity);GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0005930(axoneme);GO:0005952(cAMP-dependent protein kinase complex);GO:0006357(regulation of transcription by RNA polymerase II);GO:0006469(negative regulation of protein kinase activity);GO:0007143(female meiotic nuclear division);GO:0007507(heart development);GO:0007596(blood coagulation);GO:0008603(cAMP-dependent protein kinase regulator activity);GO:0016020(membrane);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0019904(protein domain specific binding);GO:0019934(cGMP-mediated signaling);GO:0030552(cAMP binding);GO:0031588(nucleotide-activated protein kinase complex);GO:0031594(neuromuscular junction);GO:0031625(ubiquitin protein ligase binding);GO:0032991(protein-containing complex);GO:0034199(activation of protein kinase A activity);GO:0034236(protein kinase A catalytic subunit binding);GO:0035556(intracellular signal transduction);GO:0044853(plasma membrane raft);GO:0045202(synapse);GO:0045214(sarcomere organization);GO:0045835(negative regulation of meiotic nuclear division);GO:0045859(regulation of protein kinase activity);GO:0046007(negative regulation of activated T cell proliferation);GO:0047555(3',5'-cyclic-GMP phosphodiesterase activity);GO:0060038(cardiac muscle cell proliferation);GO:0071377(cellular response to glucagon stimulus);GO:0097546(ciliary base);GO:0098978(glutamatergic synapse);GO:2000480(negative regulation of cAMP-dependent protein kinase activity)","04910(Insulin signaling pathway)","NA","NA","protein kinase cAMP-dependent type I regulatory subunit alpha [Source:HGNC Symbol;Acc:HGNC:9388]",{"v":0.054645,"d":"0.05"},{"v":0.971718,"d":"0.97"},{"v":0.796113,"d":"0.80"},{"v":0.537599,"d":"0.54"},{"v":0.042909,"d":"0.04"},{"v":63.393902,"d":"63.39"},{"v":0.0284875780800479,"d":"0.03"},{"v":-5.13352321607464,"d":"-5.13"},{"v":0.00544173103708496,"d":"0.01"},{"v":0.252165929307776,"d":"0.25"},"down","yes"]
[31753,0,"chr11","-",64224203,64226148,"ENST00000545812",7,681,"ENSG00000149743","TRPT1","GO:0000215(tRNA 2'-phosphotransferase activity);GO:0003674(molecular_function);GO:0006388(tRNA splicing, via endonucleolytic cleavage and ligation);GO:0008033(tRNA processing);GO:0008150(biological_process);GO:0016740(transferase activity);GO:0016772(transferase activity, transferring phosphorus-containing groups);GO:0045859(regulation of protein kinase activity)","NA","K10669","EC:2.7.1.160","tRNA phosphotransferase 1 [Source:HGNC Symbol;Acc:HGNC:20316]",0,{"v":2.143901,"d":"2.14"},{"v":1.914432,"d":"1.91"},0,{"v":0.010007,"d":"0.01"},{"v":0.021574,"d":"0.02"},{"v":128.505525474178,"d":"128.51"},{"v":7.005686583457,"d":"7.01"},{"v":0.00549738680779442,"d":"0.01"},{"v":0.254063889476122,"d":"0.25"},"up","yes"]
[89461,0,"chr17","-",68267026,68291116,"ENST00000327268",7,3807,"ENSG00000108932","SLC16A6","GO:0005886(plasma membrane);GO:0005887(integral component of plasma membrane);GO:0008028(monocarboxylic acid transmembrane transporter activity);GO:0015293(symporter activity);GO:0015718(monocarboxylic acid transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0055085(transmembrane transport)","NA","K08183","NA","solute carrier family 16 member 6 [Source:HGNC Symbol;Acc:HGNC:10927]",{"v":0.019869,"d":"0.02"},0,0,{"v":0.311919,"d":"0.31"},{"v":0.231363,"d":"0.23"},{"v":0.16767,"d":"0.17"},{"v":0.0279470343989468,"d":"0.03"},{"v":-5.16116099024576,"d":"-5.16"},{"v":0.00549821355819533,"d":"0.01"},{"v":0.254063889476122,"d":"0.25"},"down","yes"]
[39130,0,"chr12","-",6556871,6568324,"ENST00000322166",16,2683,"ENSG00000111641","NOP2","GO:0000027(ribosomal large subunit assembly);GO:0003723(RNA binding);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005730(nucleolus);GO:0006357(regulation of transcription by RNA polymerase II);GO:0006364(rRNA processing);GO:0008168(methyltransferase activity);GO:0008284(positive regulation of cell population proliferation);GO:0008757(S-adenosylmethionine-dependent methyltransferase activity);GO:0009383(rRNA (cytosine-C5-)-methyltransferase activity);GO:0016740(transferase activity);GO:0032259(methylation);GO:0042254(ribosome biogenesis);GO:0070475(rRNA base methylation);GO:1901796(regulation of signal transduction by p53 class mediator)","NA","K14835","EC:2.1.1.310","NOP2 nucleolar protein [Source:HGNC Symbol;Acc:HGNC:7867]",{"v":3.325538,"d":"3.33"},{"v":0.943979,"d":"0.94"},{"v":0.319974,"d":"0.32"},{"v":0.008336,"d":"0.01"},{"v":0.223438,"d":"0.22"},{"v":0.060752,"d":"0.06"},{"v":15.6891729282183,"d":"15.69"},{"v":3.97169739596278,"d":"3.97"},{"v":0.00550366862146182,"d":"0.01"},{"v":0.254063889476122,"d":"0.25"},"up","yes"]
[174294,0,"chr6","-",136259351,136289781,"ENST00000530767",13,4186,"ENSG00000029363","BCLAF1","GO:0003677(DNA binding);GO:0003723(RNA binding);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0006915(apoptotic process);GO:0016607(nuclear speck);GO:0043065(positive regulation of apoptotic process);GO:0043620(regulation of DNA-templated transcription in response to stress);GO:0045892(negative regulation of transcription, DNA-templated);GO:1990830(cellular response to leukemia inhibitory factor);GO:2000144(positive regulation of DNA-templated transcription, initiation);GO:2001022(positive regulation of response to DNA damage stimulus);GO:2001244(positive regulation of intrinsic apoptotic signaling pathway)","NA","K13087","NA","BCL2 associated transcription factor 1 [Source:HGNC Symbol;Acc:HGNC:16863]",{"v":0.228398,"d":"0.23"},{"v":0.499636,"d":"0.50"},{"v":0.525331,"d":"0.53"},{"v":11.564321,"d":"11.56"},{"v":0.47983,"d":"0.48"},{"v":0.918257,"d":"0.92"},{"v":0.0966922966782098,"d":"0.10"},{"v":-3.37045523271824,"d":"-3.37"},{"v":0.00554022555125534,"d":"0.01"},{"v":0.255426896290744,"d":"0.26"},"down","yes"]
[20457,0,"chr10","+",38010669,38057959,"ENST00000432900",5,3994,"ENSG00000189180","ZNF33A","GO:0000981(DNA-binding transcription factor activity, RNA polymerase II-specific);GO:0003676(nucleic acid binding);GO:0003677(DNA binding);GO:0003700(DNA-binding transcription factor activity);GO:0005622(intracellular);GO:0005634(nucleus);GO:0006355(regulation of transcription, DNA-templated);GO:0006357(regulation of transcription by RNA polymerase II);GO:0046872(metal ion binding)","05168(Herpes simplex virus 1 infection)","K09228","NA","zinc finger protein 33A [Source:HGNC Symbol;Acc:HGNC:13096]",{"v":0.044116,"d":"0.04"},{"v":0.134168,"d":"0.13"},{"v":0.025413,"d":"0.03"},{"v":1.372452,"d":"1.37"},{"v":1.368008,"d":"1.37"},{"v":0.058282,"d":"0.06"},{"v":0.072781628317294,"d":"0.07"},{"v":-3.78028186133482,"d":"-3.78"},{"v":0.00555905222486713,"d":"0.01"},{"v":0.255702439917904,"d":"0.26"},"down","yes"]
[37070,0,"chr11","-",119024351,119030906,"ENST00000330775",9,2103,"ENSG00000137700","SLC37A4","GO:0001780(neutrophil homeostasis);GO:0001816(cytokine production);GO:0002318(myeloid progenitor cell differentiation);GO:0005977(glycogen metabolic process);GO:0006089(lactate metabolic process);GO:0006641(triglyceride metabolic process);GO:0006874(cellular calcium ion homeostasis);GO:0007584(response to nutrient);GO:0008202(steroid metabolic process);GO:0009749(response to glucose);GO:0014070(response to organic cyclic compound);GO:0015152(glucose-6-phosphate transmembrane transporter activity);GO:0015760(glucose-6-phosphate transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0022857(transmembrane transporter activity);GO:0030593(neutrophil chemotaxis);GO:0032682(negative regulation of chemokine production);GO:0035166(post-embryonic hemopoiesis);GO:0042593(glucose homeostasis);GO:0042632(cholesterol homeostasis);GO:0043085(positive regulation of catalytic activity);GO:0043231(intracellular membrane-bounded organelle);GO:0045730(respiratory burst);GO:0055085(transmembrane transport)","04973(Carbohydrate digestion and absorption)","NA","NA","solute carrier family 37 member 4 [Source:HGNC Symbol;Acc:HGNC:4061]",{"v":0.015715,"d":"0.02"},{"v":0.001861,"d":"0.00"},{"v":0.088891,"d":"0.09"},{"v":0.258479,"d":"0.26"},{"v":0.995349,"d":"1.00"},{"v":0.689566,"d":"0.69"},{"v":0.0547840530535753,"d":"0.05"},{"v":-4.19010018579808,"d":"-4.19"},{"v":0.00556027876507416,"d":"0.01"},{"v":0.255702439917904,"d":"0.26"},"down","yes"]
[12500,0,"chr1","-",156525405,156572565,"ENST00000361170",38,6013,"ENSG00000183856","IQGAP3","GO:0000082(G1/S transition of mitotic cell cycle);GO:0000187(activation of MAPK activity);GO:0001934(positive regulation of protein phosphorylation);GO:0005515(protein binding);GO:0005516(calmodulin binding);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005911(cell-cell junction);GO:0007165(signal transduction);GO:0007265(Ras protein signal transduction);GO:0008361(regulation of cell size);GO:0010628(positive regulation of gene expression);GO:0010629(negative regulation of gene expression);GO:0016328(lateral plasma membrane);GO:0017016(Ras GTPase binding);GO:0017048(Rho GTPase binding);GO:0033601(positive regulation of mammary gland epithelial cell proliferation);GO:0043087(regulation of GTPase activity);GO:0070371(ERK1 and ERK2 cascade);GO:0070856(myosin VI light chain binding);GO:0071310(cellular response to organic substance)","04810(Regulation of actin cytoskeleton)","K05767","NA","IQ motif containing GTPase activating protein 3 [Source:HGNC Symbol;Acc:HGNC:20669]",{"v":0.130764,"d":"0.13"},{"v":0.129132,"d":"0.13"},{"v":0.123463,"d":"0.12"},{"v":1.112146,"d":"1.11"},{"v":0.861689,"d":"0.86"},{"v":0.813563,"d":"0.81"},{"v":0.137532924971604,"d":"0.14"},{"v":-2.86215105801705,"d":"-2.86"},{"v":0.00559978638236387,"d":"0.01"},{"v":0.257193728535119,"d":"0.26"},"down","yes"]
[203083,0,"chrX","-",48973723,49002264,"ENST00000376423",26,3031,"ENSG00000068400","GRIPAP1","GO:0003674(molecular_function);GO:0005515(protein binding);GO:0005654(nucleoplasm);GO:0005768(endosome);GO:0005829(cytosol);GO:0008150(biological_process);GO:0015031(protein transport);GO:0016020(membrane);GO:0030054(cell junction);GO:0030424(axon);GO:0030425(dendrite);GO:0031901(early endosome membrane);GO:0042995(cell projection);GO:0043231(intracellular membrane-bounded organelle);GO:0045202(synapse);GO:0055038(recycling endosome membrane);GO:0072562(blood microparticle);GO:0098837(postsynaptic recycling endosome);GO:0098887(neurotransmitter receptor transport, endosome to postsynaptic membrane);GO:0098978(glutamatergic synapse);GO:0098998(extrinsic component of postsynaptic early endosome membrane);GO:0099152(regulation of neurotransmitter receptor transport, endosome to postsynaptic membrane);GO:0099158(regulation of recycling endosome localization within postsynapse);GO:1905244(regulation of modification of synaptic structure)","NA","NA","NA","GRIP1 associated protein 1 [Source:HGNC Symbol;Acc:HGNC:18706]",{"v":1.762438,"d":"1.76"},{"v":2.191091,"d":"2.19"},{"v":1.837802,"d":"1.84"},{"v":8.281061,"d":"8.28"},{"v":8.558281,"d":"8.56"},{"v":9.221875,"d":"9.22"},{"v":0.222220282345218,"d":"0.22"},{"v":-2.16993759542648,"d":"-2.17"},{"v":0.00563199095005025,"d":"0.01"},{"v":0.258346251534502,"d":"0.26"},"down","yes"]
[92065,0,"chr17","+",82232232,82239498,"ENST00000392339",5,2074,"ENSG00000141526","SLC16A3","GO:0003723(RNA binding);GO:0005515(protein binding);GO:0005886(plasma membrane);GO:0005887(integral component of plasma membrane);GO:0006090(pyruvate metabolic process);GO:0008028(monocarboxylic acid transmembrane transporter activity);GO:0015129(lactate transmembrane transporter activity);GO:0015293(symporter activity);GO:0015718(monocarboxylic acid transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0031965(nuclear membrane);GO:0035873(lactate transmembrane transport);GO:0035879(plasma membrane lactate transport);GO:0050900(leukocyte migration);GO:0055085(transmembrane transport);GO:0098688(parallel fiber to Purkinje cell synapse);GO:0099061(integral component of postsynaptic density membrane)","05230(Central carbon metabolism in cancer)","K08180","NA","solute carrier family 16 member 3 [Source:HGNC Symbol;Acc:HGNC:10924]",{"v":1.009396,"d":"1.01"},{"v":0.790094,"d":"0.79"},{"v":0.038645,"d":"0.04"},0,{"v":0.030904,"d":"0.03"},{"v":0.02623,"d":"0.03"},{"v":32.1723492141282,"d":"32.17"},{"v":5.00774937983141,"d":"5.01"},{"v":0.00570179321489185,"d":"0.01"},{"v":0.261218344889055,"d":"0.26"},"up","yes"]
[204349,0,"chrX","-",73820672,73838873,"ENST00000647696",7,4318,"ENSG00000229807","XIST","NA","NA","NA","NA","X inactive specific transcript [Source:HGNC Symbol;Acc:HGNC:12810]",{"v":0.532456,"d":"0.53"},{"v":0.628547,"d":"0.63"},{"v":0.629031,"d":"0.63"},{"v":0.017661,"d":"0.02"},{"v":0.033871,"d":"0.03"},{"v":0.133913,"d":"0.13"},{"v":9.65264094475451,"d":"9.65"},{"v":3.27092371508931,"d":"3.27"},{"v":0.00571390058010836,"d":"0.01"},{"v":0.261443335107477,"d":"0.26"},"up","yes"]
[97211,0,"chr19","+",3572979,3579088,"ENST00000488973",8,2434,"ENSG00000064961","HMG20B","GO:0000981(DNA-binding transcription factor activity, RNA polymerase II-specific);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005694(chromosome);GO:0006325(chromatin organization);GO:0006357(regulation of transcription by RNA polymerase II);GO:0007049(cell cycle);GO:0007596(blood coagulation);GO:0016604(nuclear body);GO:0033234(negative regulation of protein sumoylation);GO:0035914(skeletal muscle cell differentiation);GO:0045666(positive regulation of neuron differentiation);GO:0046982(protein heterodimerization activity)","NA","NA","NA","high mobility group 20B [Source:HGNC Symbol;Acc:HGNC:5002]",{"v":1.216554,"d":"1.22"},{"v":3.665932,"d":"3.67"},{"v":3.179223,"d":"3.18"},{"v":8.883451,"d":"8.88"},{"v":15.158724,"d":"15.16"},{"v":14.027832,"d":"14.03"},{"v":0.211760113414216,"d":"0.21"},{"v":-2.2394972222644,"d":"-2.24"},{"v":0.00579571490954447,"d":"0.01"},{"v":0.264853236055032,"d":"0.26"},"down","yes"]
[200593,0,"chr9","-",136440097,136483759,"ENST00000290037",29,8982,"ENSG00000148396","SEC16A","GO:0000139(Golgi membrane);GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005794(Golgi apparatus);GO:0005829(cytosol);GO:0006888(endoplasmic reticulum to Golgi vesicle-mediated transport);GO:0007029(endoplasmic reticulum organization);GO:0007030(Golgi organization);GO:0012507(ER to Golgi transport vesicle membrane);GO:0015031(protein transport);GO:0016020(membrane);GO:0016192(vesicle-mediated transport);GO:0021762(substantia nigra development);GO:0031090(organelle membrane);GO:0032527(protein exit from endoplasmic reticulum);GO:0034976(response to endoplasmic reticulum stress);GO:0043000(Golgi to plasma membrane CFTR protein transport);GO:0043231(intracellular membrane-bounded organelle);GO:0048208(COPII vesicle coating);GO:0048471(perinuclear region of cytoplasm);GO:0050821(protein stabilization);GO:0070863(positive regulation of protein exit from endoplasmic reticulum);GO:0070971(endoplasmic reticulum exit site);GO:0070973(protein localization to endoplasmic reticulum exit site);GO:0072659(protein localization to plasma membrane)","NA","K20353","NA","SEC16 homolog A, endoplasmic reticulum export factor [Source:HGNC Symbol;Acc:HGNC:29006]",{"v":0.150083,"d":"0.15"},{"v":0.048851,"d":"0.05"},{"v":0.032831,"d":"0.03"},{"v":1.124641,"d":"1.12"},{"v":0.344657,"d":"0.34"},{"v":0.59532,"d":"0.60"},{"v":0.112255632761121,"d":"0.11"},{"v":-3.15514025657884,"d":"-3.16"},{"v":0.00588473423188806,"d":"0.01"},{"v":0.268583410357404,"d":"0.27"},"down","yes"]
[135270,0,"chr22","-",42583722,42614962,"ENST00000451060",9,3491,"ENSG00000100227","POLDIP3","GO:0000346(transcription export complex);GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0005515(protein binding);GO:0005623(cell);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0006405(RNA export from nucleus);GO:0006406(mRNA export from nucleus);GO:0006417(regulation of translation);GO:0016607(nuclear speck);GO:0016973(poly(A)+ mRNA export from nucleus);GO:0031124(mRNA 3'-end processing);GO:0036464(cytoplasmic ribonucleoprotein granule);GO:0044877(protein-containing complex binding);GO:0045727(positive regulation of translation);GO:0051028(mRNA transport)","NA","K22414","NA","DNA polymerase delta interacting protein 3 [Source:HGNC Symbol;Acc:HGNC:23782]",{"v":0.199663,"d":"0.20"},{"v":0.233916,"d":"0.23"},{"v":0.096031,"d":"0.10"},{"v":2.635186,"d":"2.64"},{"v":3.287739,"d":"3.29"},{"v":0.11515,"d":"0.12"},{"v":0.0877117293177047,"d":"0.09"},{"v":-3.51108640871255,"d":"-3.51"},{"v":0.00594369579264623,"d":"0.01"},{"v":0.270934088013598,"d":"0.27"},"down","yes"]
[56842,0,"chr14","-",55148135,55191585,"ENST00000247191",19,2881,"ENSG00000126787","DLGAP5","GO:0004721(phosphoprotein phosphatase activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005739(mitochondrion);GO:0005815(microtubule organizing center);GO:0005819(spindle);GO:0005829(cytosol);GO:0005856(cytoskeleton);GO:0006470(protein dephosphorylation);GO:0007049(cell cycle);GO:0007079(mitotic chromosome movement towards spindle pole);GO:0007221(positive regulation of transcription of Notch receptor target);GO:0008283(cell population proliferation);GO:0023052(signaling);GO:0031616(spindle pole centrosome);GO:0045842(positive regulation of mitotic metaphase/anaphase transition)","NA","K16804","NA","DLG associated protein 5 [Source:HGNC Symbol;Acc:HGNC:16864]",0,0,{"v":0.175505,"d":"0.18"},{"v":1.853364,"d":"1.85"},{"v":2.027395,"d":"2.03"},{"v":1.209369,"d":"1.21"},{"v":0.034479486566939,"d":"0.03"},{"v":-4.85811789831889,"d":"-4.86"},{"v":0.00599169796423715,"d":"0.01"},{"v":0.272505030005976,"d":"0.27"},"down","yes"]
[189258,0,"chr8","-",53966552,54022448,"ENST00000396401",9,2718,"ENSG00000187735","TCEA1","GO:0003676(nucleic acid binding);GO:0003677(DNA binding);GO:0003746(translation elongation factor activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005669(transcription factor TFIID complex);GO:0005730(nucleolus);GO:0006283(transcription-coupled nucleotide-excision repair);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0006366(transcription by RNA polymerase II);GO:0006368(transcription elongation from RNA polymerase II promoter);GO:0006414(translational elongation);GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:1901919(positive regulation of exoribonuclease activity)","NA","K03145","NA","transcription elongation factor A1 [Source:HGNC Symbol;Acc:HGNC:11612]",{"v":0.658541,"d":"0.66"},{"v":0.270392,"d":"0.27"},{"v":4.082406,"d":"4.08"},{"v":5.24793,"d":"5.25"},{"v":30.408476,"d":"30.41"},{"v":5.340923,"d":"5.34"},{"v":0.122235743699303,"d":"0.12"},{"v":-3.03226188078273,"d":"-3.03"},{"v":0.00599316044521814,"d":"0.01"},{"v":0.272505030005976,"d":"0.27"},"down","yes"]
[32627,0,"chr11","+",66002581,66004131,"ENST00000533166",3,1135,"ENSG00000175334","BANF1","GO:0000793(condensed chromosome);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005635(nuclear envelope);GO:0005654(nucleoplasm);GO:0005694(chromosome);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0007084(mitotic nuclear envelope reassembly);GO:0008022(protein C-terminus binding);GO:0009615(response to virus);GO:0015074(DNA integration);GO:0016032(viral process);GO:0019899(enzyme binding);GO:0042802(identical protein binding);GO:0042803(protein homodimerization activity);GO:0045071(negative regulation of viral genome replication);GO:0047485(protein N-terminus binding);GO:0051169(nuclear transport);GO:0075713(establishment of integrated proviral latency);GO:0097726(LEM domain binding)","NA","K21870","NA","barrier to autointegration factor 1 [Source:HGNC Symbol;Acc:HGNC:17397]",{"v":1.096949,"d":"1.10"},{"v":0.913933,"d":"0.91"},{"v":1.440405,"d":"1.44"},{"v":15.095275,"d":"15.10"},{"v":1.171424,"d":"1.17"},{"v":13.222495,"d":"13.22"},{"v":0.11703565041486,"d":"0.12"},{"v":-3.09498003651086,"d":"-3.09"},{"v":0.00601037092573375,"d":"0.01"},{"v":0.272945969664884,"d":"0.27"},"down","yes"]
[199066,0,"chr9","+",125261832,125363329,"ENST00000394105",27,5207,"ENSG00000165219","GAPVD1","GO:0005085(guanyl-nucleotide exchange factor activity);GO:0005096(GTPase activator activity);GO:0005768(endosome);GO:0005829(cytosol);GO:0006897(endocytosis);GO:0007165(signal transduction);GO:0016020(membrane);GO:0032794(GTPase activating protein binding);GO:0043087(regulation of GTPase activity);GO:0043547(positive regulation of GTPase activity);GO:0045296(cadherin binding);GO:0051223(regulation of protein transport);GO:0061024(membrane organization)","NA","NA","NA","GTPase activating protein and VPS9 domains 1 [Source:HGNC Symbol;Acc:HGNC:23375]",{"v":0.263011,"d":"0.26"},{"v":3.522677,"d":"3.52"},{"v":1.071378,"d":"1.07"},{"v":0.00232,"d":"0.00"},{"v":0.120721,"d":"0.12"},{"v":0.195853,"d":"0.20"},{"v":15.2309733014732,"d":"15.23"},{"v":3.92893623187621,"d":"3.93"},{"v":0.00607703492352614,"d":"0.01"},{"v":0.275478911611591,"d":"0.28"},"up","yes"]
[116290,0,"chr2","-",111207776,111495048,"ENST00000439362",6,1522,"ENSG00000172965","MIR4435-2HG","NA","NA","NA","NA","MIR4435-2 host gene [Source:HGNC Symbol;Acc:HGNC:35163]",{"v":0.301083,"d":"0.30"},{"v":0.02338,"d":"0.02"},{"v":0.063809,"d":"0.06"},{"v":1.344284,"d":"1.34"},{"v":0.175732,"d":"0.18"},{"v":4.526621,"d":"4.53"},{"v":0.0642128839551638,"d":"0.06"},{"v":-3.96099339471147,"d":"-3.96"},{"v":0.00608131260975767,"d":"0.01"},{"v":0.275478911611591,"d":"0.28"},"down","yes"]
[184603,0,"chr7","+",141551189,141655244,"ENST00000355413",16,3849,"ENSG00000006530","AGK","GO:0000166(nucleotide binding);GO:0001727(lipid kinase activity);GO:0001729(ceramide kinase activity);GO:0003951(NAD+ kinase activity);GO:0004143(diacylglycerol kinase activity);GO:0005524(ATP binding);GO:0005739(mitochondrion);GO:0005741(mitochondrial outer membrane);GO:0005743(mitochondrial inner membrane);GO:0005758(mitochondrial intermembrane space);GO:0005829(cytosol);GO:0016020(membrane);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0016740(transferase activity);GO:0031305(integral component of mitochondrial inner membrane);GO:0042721(TIM22 mitochondrial import inner membrane insertion complex);GO:0043231(intracellular membrane-bounded organelle);GO:0045039(protein insertion into mitochondrial inner membrane);GO:0046474(glycerophospholipid biosynthetic process);GO:0046486(glycerolipid metabolic process);GO:0046513(ceramide biosynthetic process);GO:0046834(lipid phosphorylation);GO:0047620(acylglycerol kinase activity)","00561(Glycerolipid metabolism)","K09881","EC:2.7.1.94","acylglycerol kinase [Source:HGNC Symbol;Acc:HGNC:21869]",{"v":0.187172,"d":"0.19"},{"v":2.025013,"d":"2.03"},{"v":2.073745,"d":"2.07"},{"v":0.088077,"d":"0.09"},{"v":0.133193,"d":"0.13"},{"v":0.190676,"d":"0.19"},{"v":10.4041063634554,"d":"10.40"},{"v":3.37908114834331,"d":"3.38"},{"v":0.00613175386377888,"d":"0.01"},{"v":0.27741795500758,"d":"0.28"},"up","yes"]
[93237,0,"chr18","+",12991362,13125036,"ENST00000506447",45,7960,"ENSG00000101639","CEP192","GO:0000086(G2/M transition of mitotic cell cycle);GO:0000242(pericentriolar material);GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0005813(centrosome);GO:0005814(centriole);GO:0005829(cytosol);GO:0005856(cytoskeleton);GO:0009617(response to bacterium);GO:0010389(regulation of G2/M transition of mitotic cell cycle);GO:0010923(negative regulation of phosphatase activity);GO:0019902(phosphatase binding);GO:0051298(centrosome duplication);GO:0071539(protein localization to centrosome);GO:0090222(centrosome-templated microtubule nucleation);GO:0090307(mitotic spindle assembly);GO:0097711(ciliary basal body-plasma membrane docking)","NA","K16725","NA","centrosomal protein 192 [Source:HGNC Symbol;Acc:HGNC:25515]",{"v":0.317116,"d":"0.32"},{"v":0.217043,"d":"0.22"},{"v":0.204759,"d":"0.20"},{"v":2.36494,"d":"2.36"},{"v":2.352474,"d":"2.35"},{"v":0.441933,"d":"0.44"},{"v":0.14321928724701,"d":"0.14"},{"v":-2.80370230241158,"d":"-2.80"},{"v":0.00619141302469974,"d":"0.01"},{"v":0.279517249173914,"d":"0.28"},"down","yes"]
[21393,0,"chr10","-",63167225,63465977,"ENST00000399262",26,8758,"ENSG00000171988","JMJD1C","GO:0000785(chromatin);GO:0000976(transcription regulatory region sequence-specific DNA binding);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0006325(chromatin organization);GO:0006355(regulation of transcription, DNA-templated);GO:0007596(blood coagulation);GO:0016491(oxidoreductase activity);GO:0031490(chromatin DNA binding);GO:0032454(histone demethylase activity (H3-K9 specific));GO:0033169(histone H3-K9 demethylation);GO:0046872(metal ion binding);GO:0046966(thyroid hormone receptor binding);GO:0051213(dioxygenase activity);GO:0055114(oxidation-reduction process)","05202(Transcriptional misregulation in cancer)","K11449","EC:1.14.11.-","jumonji domain containing 1C [Source:HGNC Symbol;Acc:HGNC:12313]",{"v":0.034006,"d":"0.03"},{"v":3.946105,"d":"3.95"},{"v":0.036922,"d":"0.04"},{"v":0.020787,"d":"0.02"},{"v":0.114296,"d":"0.11"},{"v":0.015453,"d":"0.02"},{"v":26.684866078546,"d":"26.68"},{"v":4.73794986587998,"d":"4.74"},{"v":0.00619817049104486,"d":"0.01"},{"v":0.279517249173914,"d":"0.28"},"up","yes"]
[166458,0,"chr5","-",179862066,179907859,"ENST00000356834",22,5173,"ENSG00000197226","TBC1D9B","GO:0005096(GTPase activator activity);GO:0005509(calcium ion binding);GO:0005515(protein binding);GO:0005623(cell);GO:0006886(intracellular protein transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0017137(Rab GTPase binding);GO:0090630(activation of GTPase activity)","NA","K19951","NA","TBC1 domain family member 9B [Source:HGNC Symbol;Acc:HGNC:29097]",{"v":10.551998,"d":"10.55"},{"v":3.351796,"d":"3.35"},{"v":10.672047,"d":"10.67"},{"v":1.671658,"d":"1.67"},{"v":2.560637,"d":"2.56"},{"v":0.870835,"d":"0.87"},{"v":4.81583675117036,"d":"4.82"},{"v":2.26778648797204,"d":"2.27"},{"v":0.0062084392605501,"d":"0.01"},{"v":0.279517249173914,"d":"0.28"},"up","yes"]
[103459,0,"chr19","+",38619193,38635744,"ENST00000545173",7,1327,"ENSG00000178982","EIF3K","GO:0001732(formation of cytoplasmic translation initiation complex);GO:0002183(cytoplasmic translational initiation);GO:0003723(RNA binding);GO:0003743(translation initiation factor activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005852(eukaryotic translation initiation factor 3 complex);GO:0006412(translation);GO:0006413(translational initiation);GO:0006446(regulation of translational initiation);GO:0016020(membrane);GO:0016282(eukaryotic 43S preinitiation complex);GO:0033290(eukaryotic 48S preinitiation complex);GO:0043022(ribosome binding)","NA","K15028","NA","eukaryotic translation initiation factor 3 subunit K [Source:HGNC Symbol;Acc:HGNC:24656]",{"v":20.573727,"d":"20.57"},{"v":31.063534,"d":"31.06"},{"v":17.325407,"d":"17.33"},{"v":6.45162,"d":"6.45"},{"v":5.333276,"d":"5.33"},{"v":2.040809,"d":"2.04"},{"v":4.98800372205251,"d":"4.99"},{"v":2.31846254170822,"d":"2.32"},{"v":0.00620892981236854,"d":"0.01"},{"v":0.279517249173914,"d":"0.28"},"up","yes"]
[37452,0,"chr11","-",122089106,122102166,"ENST00000529823",2,3334,"ENSG00000255248","MIR100HG","NA","NA","NA","NA","mir-100-let-7a-2-mir-125b-1 cluster host gene [Source:HGNC Symbol;Acc:HGNC:39522]",{"v":0.110787,"d":"0.11"},{"v":0.293895,"d":"0.29"},{"v":0.185127,"d":"0.19"},{"v":0.098135,"d":"0.10"},{"v":1.793516,"d":"1.79"},{"v":5.455558,"d":"5.46"},{"v":0.080276605715177,"d":"0.08"},{"v":-3.63887657234433,"d":"-3.64"},{"v":0.00622398170823729,"d":"0.01"},{"v":0.279848088440917,"d":"0.28"},"down","yes"]
[11626,0,"chr1","-",153959112,153967712,"ENST00000310483",5,2427,"ENSG00000143570","SLC39A1","GO:0001701(in utero embryonic development);GO:0005102(signaling receptor binding);GO:0005385(zinc ion transmembrane transporter activity);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005886(plasma membrane);GO:0006811(ion transport);GO:0006812(cation transport);GO:0006829(zinc ion transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0022890(inorganic cation transmembrane transporter activity);GO:0030001(metal ion transport);GO:0046873(metal ion transmembrane transporter activity);GO:0048701(embryonic cranial skeleton morphogenesis);GO:0055085(transmembrane transport);GO:0060173(limb development);GO:0071577(zinc ion transmembrane transport)","NA","K14709","NA","solute carrier family 39 member 1 [Source:HGNC Symbol;Acc:HGNC:12876]",{"v":6.381873,"d":"6.38"},{"v":0.199895,"d":"0.20"},{"v":0.773251,"d":"0.77"},{"v":0.103713,"d":"0.10"},{"v":0.129453,"d":"0.13"},{"v":0.295457,"d":"0.30"},{"v":13.9135433002348,"d":"13.91"},{"v":3.79841796629226,"d":"3.80"},{"v":0.00626765111806319,"d":"0.01"},{"v":0.281463244893987,"d":"0.28"},"up","yes"]
[170984,0,"chr6","+",44247087,44253883,"ENST00000353801",12,2582,"ENSG00000096384","HSP90AB1","GO:0000166(nucleotide binding);GO:0001890(placenta development);GO:0002134(UTP binding);GO:0002135(CTP binding);GO:0003723(RNA binding);GO:0003725(double-stranded RNA binding);GO:0005515(protein binding);GO:0005524(ATP binding);GO:0005525(GTP binding);GO:0005576(extracellular region);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0005739(mitochondrion);GO:0005765(lysosomal membrane);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0006457(protein folding);GO:0006805(xenobiotic metabolic process);GO:0006986(response to unfolded protein);GO:0007004(telomere maintenance via telomerase);GO:0008144(drug binding);GO:0008180(COP9 signalosome);GO:0009651(response to salt stress);GO:0009986(cell surface);GO:0010033(response to organic substance);GO:0016020(membrane);GO:0016234(inclusion body);GO:0016323(basolateral plasma membrane);GO:0016324(apical plasma membrane);GO:0017098(sulfonylurea receptor binding);GO:0019062(virion attachment to host cell);GO:0019887(protein kinase regulator activity);GO:0019900(kinase binding);GO:0019901(protein kinase binding);GO:0021955(central nervous system neuron axonogenesis);GO:0023026(MHC class II protein complex binding);GO:0030010(establishment of cell polarity);GO:0030235(nitric-oxide synthase regulator activity);GO:0030511(positive regulation of transforming growth factor beta receptor signaling pathway);GO:0030911(TPR domain binding);GO:0031072(heat shock protein binding);GO:0031396(regulation of protein ubiquitination);GO:0031526(brush border membrane);GO:0031625(ubiquitin protein ligase binding);GO:0032092(positive regulation of protein binding);GO:0032435(negative regulation of proteasomal ubiquitin-dependent protein catabolic process);GO:0032516(positive regulation of phosphoprotein phosphatase activity);GO:0032564(dATP binding);GO:0032991(protein-containing complex);GO:0033138(positive regulation of peptidyl-serine phosphorylation);GO:0034751(aryl hydrocarbon receptor complex);GO:0034774(secretory granule lumen);GO:0035690(cellular response to drug);GO:0038096(Fc-gamma receptor signaling pathway involved in phagocytosis);GO:0042220(response to cocaine);GO:0042277(peptide binding);GO:0042470(melanosome);GO:0042493(response to drug);GO:0042623(ATPase activity, coupled);GO:0042802(identical protein binding);GO:0042803(protein homodimerization activity);GO:0042826(histone deacetylase binding);GO:0043008(ATP-dependent protein binding);GO:0043025(neuronal cell body);GO:0043066(negative regulation of apoptotic process);GO:0043312(neutrophil degranulation);GO:0043524(negative regulation of neuron apoptotic process);GO:0044294(dendritic growth cone);GO:0044295(axonal growth cone);GO:0044325(ion channel binding);GO:0045296(cadherin binding);GO:0045429(positive regulation of nitric oxide biosynthetic process);GO:0045597(positive regulation of cell differentiation);GO:0045793(positive regulation of cell size);GO:0046983(protein dimerization activity);GO:0048156(tau protein binding);GO:0048471(perinuclear region of cytoplasm);GO:0048675(axon extension);GO:0050821(protein stabilization);GO:0051082(unfolded protein binding);GO:0051131(chaperone-mediated protein complex assembly);GO:0051248(negative regulation of protein metabolic process);GO:0051897(positive regulation of protein kinase B signaling);GO:0051973(positive regulation of telomerase activity);GO:0060334(regulation of interferon-gamma-mediated signaling pathway);GO:0060338(regulation of type I interferon-mediated signaling pathway);GO:0070062(extracellular exosome);GO:0070182(DNA polymerase binding);GO:0071157(negative regulation of cell cycle arrest);GO:0071353(cellular response to interleukin-4);GO:0071407(cellular response to organic cyclic compound);GO:0071902(positive regulation of protein serine/threonine kinase activity);GO:0097435(supramolecular fiber organization);GO:0097718(disordered domain specific binding);GO:1900034(regulation of cellular response to heat);GO:1901389(negative regulation of transforming growth factor beta activation);GO:1901799(negative regulation of proteasomal protein catabolic process);GO:1902949(positive regulation of tau-protein kinase activity);GO:1903660(negative regulation of complement-dependent cytotoxicity);GO:1903827(regulation of cellular protein localization);GO:1904031(positive regulation of cyclin-dependent protein kinase activity);GO:1904813(ficolin-1-rich granule lumen);GO:1905323(telomerase holoenzyme complex assembly);GO:1990226(histone methyltransferase binding);GO:1990565(HSP90-CDC37 chaperone complex);GO:1990913(sperm head plasma membrane);GO:1990917(ooplasm);GO:2000010(positive regulation of protein localization to cell surface)","04141(Protein processing in endoplasmic reticulum);04151(PI3K-Akt signaling pathway);04217(Necroptosis);04612(Antigen processing and presentation);04621(NOD-like receptor signaling pathway);04657(IL-17 signaling pathway);04659(Th17 cell differentiation);04914(Progesterone-mediated oocyte maturation);04915(Estrogen signaling pathway);05200(Pathways in cancer);05215(Prostate cancer);05418(Fluid shear stress and atherosclerosis)","K04079","NA","heat shock protein 90 alpha family class B member 1 [Source:HGNC Symbol;Acc:HGNC:5258]",{"v":0.505789,"d":"0.51"},{"v":1.414936,"d":"1.41"},{"v":0.633895,"d":"0.63"},{"v":1.441917,"d":"1.44"},{"v":0.369191,"d":"0.37"},{"v":29.556643,"d":"29.56"},{"v":0.0814409678271164,"d":"0.08"},{"v":-3.61810148357864,"d":"-3.62"},{"v":0.00631452534842409,"d":"0.01"},{"v":0.283218155442281,"d":"0.28"},"down","yes"]
[129285,0,"chr21","+",15730025,15880069,"ENST00000400183",26,5341,"ENSG00000155313","USP25","GO:0004197(cysteine-type endopeptidase activity);GO:0004843(thiol-dependent ubiquitin-specific protease activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005783(endoplasmic reticulum);GO:0005829(cytosol);GO:0006464(cellular protein modification process);GO:0006508(proteolysis);GO:0006511(ubiquitin-dependent protein catabolic process);GO:0008233(peptidase activity);GO:0008234(cysteine-type peptidase activity);GO:0016579(protein deubiquitination);GO:0016787(hydrolase activity);GO:0031625(ubiquitin protein ligase binding);GO:0031647(regulation of protein stability);GO:0036459(thiol-dependent ubiquitinyl hydrolase activity);GO:0043130(ubiquitin binding);GO:0051117(ATPase binding);GO:0070536(protein K63-linked deubiquitination);GO:0071108(protein K48-linked deubiquitination);GO:1904293(negative regulation of ERAD pathway);GO:1904455(ubiquitin-specific protease activity involved in negative regulation of ERAD pathway)","04657(IL-17 signaling pathway)","K11849","EC:3.4.19.12","ubiquitin specific peptidase 25 [Source:HGNC Symbol;Acc:HGNC:12624]",{"v":0.004075,"d":"0.00"},{"v":0.355573,"d":"0.36"},{"v":0.762853,"d":"0.76"},{"v":0.015689,"d":"0.02"},{"v":0.018455,"d":"0.02"},0,{"v":32.875497891284,"d":"32.88"},{"v":5.03894083871731,"d":"5.04"},{"v":0.00632819448016886,"d":"0.01"},{"v":0.283406013998225,"d":"0.28"},"up","yes"]
[28930,0,"chr11","+",33257381,33357023,"ENST00000303296",17,7614,"ENSG00000110422","HIPK3","GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005524(ATP binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0006468(protein phosphorylation);GO:0006915(apoptotic process);GO:0009299(mRNA transcription);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0016604(nuclear body);GO:0016605(PML body);GO:0016740(transferase activity);GO:0018105(peptidyl-serine phosphorylation);GO:0018107(peptidyl-threonine phosphorylation);GO:0043066(negative regulation of apoptotic process);GO:0043508(negative regulation of JUN kinase activity)","04218(Cellular senescence)","K08826","EC:2.7.11.1","homeodomain interacting protein kinase 3 [Source:HGNC Symbol;Acc:HGNC:4915]",{"v":2.102926,"d":"2.10"},{"v":2.517352,"d":"2.52"},{"v":1.561551,"d":"1.56"},{"v":0.321366,"d":"0.32"},{"v":0.364507,"d":"0.36"},{"v":0.404586,"d":"0.40"},{"v":5.66901552465521,"d":"5.67"},{"v":2.50309821999742,"d":"2.50"},{"v":0.00633431553444973,"d":"0.01"},{"v":0.283406013998225,"d":"0.28"},"up","yes"]
[192971,0,"chr8","-",134477792,134713049,"ENST00000523243",17,4774,"ENSG00000066827","ZFAT","GO:0000981(DNA-binding transcription factor activity, RNA polymerase II-specific);GO:0001228(DNA-binding transcription activator activity, RNA polymerase II-specific);GO:0002244(hematopoietic progenitor cell differentiation);GO:0003676(nucleic acid binding);GO:0003677(DNA binding);GO:0003700(DNA-binding transcription factor activity);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0006355(regulation of transcription, DNA-templated);GO:0006357(regulation of transcription by RNA polymerase II);GO:0030097(hemopoiesis);GO:0045944(positive regulation of transcription by RNA polymerase II);GO:0046872(metal ion binding);GO:0060712(spongiotrophoblast layer development)","NA","NA","NA","zinc finger and AT-hook domain containing [Source:HGNC Symbol;Acc:HGNC:19899]",0,{"v":0.045851,"d":"0.05"},{"v":0.008261,"d":"0.01"},{"v":0.265962,"d":"0.27"},{"v":0.636312,"d":"0.64"},{"v":0.179598,"d":"0.18"},{"v":0.0500170075572711,"d":"0.05"},{"v":-4.32143744395972,"d":"-4.32"},{"v":0.00635309513040528,"d":"0.01"},{"v":0.283896612653904,"d":"0.28"},"down","yes"]
[47911,0,"chr12","-",110452487,110468721,"ENST00000543199",8,1604,"ENSG00000111231","GPN3","GO:0000166(nucleotide binding);GO:0003924(GTPase activity);GO:0005515(protein binding);GO:0005525(GTP binding);GO:0016787(hydrolase activity);GO:0032991(protein-containing complex)","NA","K06883","NA","GPN-loop GTPase 3 [Source:HGNC Symbol;Acc:HGNC:30186]",0,{"v":2.62483,"d":"2.62"},{"v":2.02476,"d":"2.02"},0,{"v":0.068449,"d":"0.07"},0,{"v":67.9278002600476,"d":"67.93"},{"v":6.08593023031454,"d":"6.09"},{"v":0.00640004988194138,"d":"0.01"},{"v":0.285643503944632,"d":"0.29"},"up","yes"]
[51069,0,"chr13","-",36301638,36346394,"ENST00000438666",9,4900,"ENSG00000133104","SPART","GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0005741(mitochondrial outer membrane);GO:0005811(lipid droplet);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0009838(abscission);GO:0030496(midbody);GO:0030514(negative regulation of BMP signaling pathway);GO:0031625(ubiquitin protein ligase binding);GO:0034389(lipid droplet organization);GO:0045202(synapse);GO:0048698(negative regulation of collateral sprouting in absence of injury);GO:0050905(neuromuscular process);GO:0051301(cell division);GO:0051881(regulation of mitochondrial membrane potential);GO:0060612(adipose tissue development)","04144(Endocytosis)","K19366","NA","spartin [Source:HGNC Symbol;Acc:HGNC:18514]",{"v":4.067524,"d":"4.07"},{"v":6.446079,"d":"6.45"},{"v":3.392516,"d":"3.39"},{"v":15.941218,"d":"15.94"},{"v":17.441002,"d":"17.44"},{"v":16.076685,"d":"16.08"},{"v":0.281165120821013,"d":"0.28"},{"v":-1.83051045901028,"d":"-1.83"},{"v":0.00643856960114046,"d":"0.01"},{"v":0.287010102588261,"d":"0.29"},"down","yes"]
[7125,0,"chr1","+",65420652,65641559,"ENST00000349533",20,8227,"ENSG00000116678","LEPR","GO:0001525(angiogenesis);GO:0004888(transmembrane signaling receptor activity);GO:0004896(cytokine receptor activity);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0005886(plasma membrane);GO:0005977(glycogen metabolic process);GO:0006112(energy reserve metabolic process);GO:0006909(phagocytosis);GO:0007166(cell surface receptor signaling pathway);GO:0007275(multicellular organism development);GO:0008203(cholesterol metabolic process);GO:0009897(external side of plasma membrane);GO:0010507(negative regulation of autophagy);GO:0014009(glial cell proliferation);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016323(basolateral plasma membrane);GO:0017046(peptide hormone binding);GO:0019953(sexual reproduction);GO:0019955(cytokine binding);GO:0030217(T cell differentiation);GO:0033210(leptin-mediated signaling pathway);GO:0038021(leptin receptor activity);GO:0042593(glucose homeostasis);GO:0042802(identical protein binding);GO:0043235(receptor complex);GO:0044321(response to leptin);GO:0045721(negative regulation of gluconeogenesis);GO:0046850(regulation of bone remodeling);GO:0051346(negative regulation of hydrolase activity);GO:0060259(regulation of feeding behavior);GO:0097009(energy homeostasis);GO:0098868(bone growth);GO:0120162(positive regulation of cold-induced thermogenesis)","04060(Cytokine-cytokine receptor interaction);04080(Neuroactive ligand-receptor interaction);04152(AMPK signaling pathway);04630(Jak-STAT signaling pathway);04920(Adipocytokine signaling pathway);04932(Non-alcoholic fatty liver disease (NAFLD))","K05062","NA","leptin receptor [Source:HGNC Symbol;Acc:HGNC:6554]",{"v":0.081646,"d":"0.08"},{"v":0.066865,"d":"0.07"},{"v":0.088182,"d":"0.09"},{"v":0.863437,"d":"0.86"},{"v":0.219785,"d":"0.22"},{"v":0.79825,"d":"0.80"},{"v":0.125802031600789,"d":"0.13"},{"v":-2.9907728741271,"d":"-2.99"},{"v":0.00651118015351192,"d":"0.01"},{"v":0.289891145805255,"d":"0.29"},"down","yes"]
[21833,0,"chr10","-",72096521,72216288,"ENST00000317168",10,2002,"ENSG00000138303","ASCC1","GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005667(transcription factor complex);GO:0006281(DNA repair);GO:0006307(DNA dealkylation involved in DNA repair);GO:0006355(regulation of transcription, DNA-templated);GO:0006974(cellular response to DNA damage stimulus);GO:0016607(nuclear speck);GO:0031594(neuromuscular junction)","NA","K18666","NA","activating signal cointegrator 1 complex subunit 1 [Source:HGNC Symbol;Acc:HGNC:24268]",{"v":0.018335,"d":"0.02"},{"v":0.012051,"d":"0.01"},{"v":0.246313,"d":"0.25"},{"v":4.822625,"d":"4.82"},{"v":0.026174,"d":"0.03"},{"v":1.764784,"d":"1.76"},{"v":0.0418379870638956,"d":"0.04"},{"v":-4.57904274839052,"d":"-4.58"},{"v":0.0065556520310607,"d":"0.01"},{"v":0.291513877954021,"d":"0.29"},"down","yes"]
[159490,0,"chr5","+",65988633,66078936,"ENST00000508515",23,4374,"ENSG00000112851","ERBIN","GO:0005102(signaling receptor binding);GO:0005176(ErbB-2 class receptor binding);GO:0005200(structural constituent of cytoskeleton);GO:0005515(protein binding);GO:0005604(basement membrane);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005886(plasma membrane);GO:0006605(protein targeting);GO:0007155(cell adhesion);GO:0007165(signal transduction);GO:0007173(epidermal growth factor receptor signaling pathway);GO:0007229(integrin-mediated signaling pathway);GO:0009925(basal plasma membrane);GO:0016020(membrane);GO:0016323(basolateral plasma membrane);GO:0016607(nuclear speck);GO:0030054(cell junction);GO:0030056(hemidesmosome);GO:0031965(nuclear membrane);GO:0032088(negative regulation of NF-kappaB transcription factor activity);GO:0032495(response to muramyl dipeptide);GO:0032496(response to lipopolysaccharide);GO:0038128(ERBB2 signaling pathway);GO:0045104(intermediate filament cytoskeleton organization);GO:0045175(basal protein localization);GO:0045197(establishment or maintenance of epithelial cell apical/basal polarity);GO:0070433(negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway);GO:0071356(cellular response to tumor necrosis factor);GO:0071638(negative regulation of monocyte chemotactic protein-1 production);GO:0098794(postsynapse);GO:0098978(glutamatergic synapse);GO:0099072(regulation of postsynaptic membrane neurotransmitter receptor levels)","04621(NOD-like receptor signaling pathway)","K12796","NA","erbb2 interacting protein [Source:HGNC Symbol;Acc:HGNC:15842]",{"v":0.066422,"d":"0.07"},{"v":0.081767,"d":"0.08"},{"v":0.142204,"d":"0.14"},{"v":0.104649,"d":"0.10"},{"v":1.551177,"d":"1.55"},{"v":1.413772,"d":"1.41"},{"v":0.0946029414926645,"d":"0.09"},{"v":-3.40197114774383,"d":"-3.40"},{"v":0.00662760543326117,"d":"0.01"},{"v":0.294301253682772,"d":"0.29"},"down","yes"]
[131365,0,"chr21","+",46635595,46665117,"ENST00000451211",8,1878,"ENSG00000160310","PRMT2","GO:0003713(transcription coactivator activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005730(nucleolus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0006355(regulation of transcription, DNA-templated);GO:0006479(protein methylation);GO:0007165(signal transduction);GO:0008168(methyltransferase activity);GO:0008469(histone-arginine N-methyltransferase activity);GO:0016274(protein-arginine N-methyltransferase activity);GO:0016571(histone methylation);GO:0016740(transferase activity);GO:0019919(peptidyl-arginine methylation, to asymmetrical-dimethyl arginine);GO:0030331(estrogen receptor binding);GO:0032088(negative regulation of NF-kappaB transcription factor activity);GO:0032259(methylation);GO:0033142(progesterone receptor binding);GO:0034969(histone arginine methylation);GO:0035242(protein-arginine omega-N asymmetric methyltransferase activity);GO:0042054(histone methyltransferase activity);GO:0042803(protein homodimerization activity);GO:0042974(retinoic acid receptor binding);GO:0042975(peroxisome proliferator activated receptor binding);GO:0043065(positive regulation of apoptotic process);GO:0044877(protein-containing complex binding);GO:0045892(negative regulation of transcription, DNA-templated);GO:0045893(positive regulation of transcription, DNA-templated);GO:0046966(thyroid hormone receptor binding);GO:0048588(developmental cell growth);GO:0050681(androgen receptor binding);GO:0060765(regulation of androgen receptor signaling pathway);GO:2000134(negative regulation of G1/S transition of mitotic cell cycle)","NA","K11435","EC:2.1.1.319","protein arginine methyltransferase 2 [Source:HGNC Symbol;Acc:HGNC:5186]",0,{"v":0.078185,"d":"0.08"},{"v":0.051535,"d":"0.05"},{"v":1.76691,"d":"1.77"},{"v":2.046317,"d":"2.05"},{"v":0.003039,"d":"0.00"},{"v":0.033991341274429,"d":"0.03"},{"v":-4.87868889903992,"d":"-4.88"},{"v":0.0066384249394936,"d":"0.01"},{"v":0.294301253682772,"d":"0.29"},"down","yes"]
[6962,0,"chr1","+",62784132,62865516,"ENST00000317868",11,2944,"ENSG00000125703","ATG4C","GO:0000045(autophagosome assembly);GO:0004197(cysteine-type endopeptidase activity);GO:0005576(extracellular region);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0006508(proteolysis);GO:0006612(protein targeting to membrane);GO:0006914(autophagy);GO:0008233(peptidase activity);GO:0008234(cysteine-type peptidase activity);GO:0015031(protein transport);GO:0016787(hydrolase activity)","04136(Autophagy - other);04140(Autophagy - animal)","K08342","EC:3.4.22.-","autophagy related 4C cysteine peptidase [Source:HGNC Symbol;Acc:HGNC:16040]",{"v":6.140497,"d":"6.14"},{"v":0.946677,"d":"0.95"},{"v":0.435273,"d":"0.44"},{"v":0.250201,"d":"0.25"},{"v":0.028917,"d":"0.03"},{"v":0.308749,"d":"0.31"},{"v":12.7961715830281,"d":"12.80"},{"v":3.67764033758676,"d":"3.68"},{"v":0.00664263771042865,"d":"0.01"},{"v":0.294301253682772,"d":"0.29"},"up","yes"]
[136770,0,"chr3","+",10248023,10281216,"ENST00000287652",8,5342,"ENSG00000157014","TATDN2","GO:0004518(nuclease activity);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0006259(DNA metabolic process);GO:0016607(nuclear speck);GO:0016787(hydrolase activity);GO:0016788(hydrolase activity, acting on ester bonds);GO:0016888(endodeoxyribonuclease activity, producing 5'-phosphomonoesters);GO:0036498(IRE1-mediated unfolded protein response);GO:0046872(metal ion binding);GO:0090305(nucleic acid phosphodiester bond hydrolysis)","NA","K03424","EC:3.1.21.-","TatD DNase domain containing 2 [Source:HGNC Symbol;Acc:HGNC:28988]",{"v":0.518821,"d":"0.52"},{"v":0.702924,"d":"0.70"},{"v":2.170744,"d":"2.17"},{"v":8.357041,"d":"8.36"},{"v":7.880194,"d":"7.88"},{"v":2.112245,"d":"2.11"},{"v":0.184882023904765,"d":"0.18"},{"v":-2.43532313669038,"d":"-2.44"},{"v":0.00665184626785002,"d":"0.01"},{"v":0.294350273947614,"d":"0.29"},"down","yes"]
[199416,0,"chr9","+",128068201,128109244,"ENST00000373068",10,3431,"ENSG00000148339","SLC25A25","GO:0002021(response to dietary excess);GO:0005347(ATP transmembrane transporter activity);GO:0005509(calcium ion binding);GO:0005739(mitochondrion);GO:0005743(mitochondrial inner membrane);GO:0014823(response to activity);GO:0015867(ATP transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0022857(transmembrane transporter activity);GO:0032094(response to food);GO:0035264(multicellular organism growth);GO:0043010(camera-type eye development);GO:0045333(cellular respiration);GO:0046034(ATP metabolic process);GO:0046872(metal ion binding);GO:0055085(transmembrane transport);GO:0060612(adipose tissue development);GO:0070588(calcium ion transmembrane transport)","NA","K14684","NA","solute carrier family 25 member 25 [Source:HGNC Symbol;Acc:HGNC:20663]",{"v":4.422225,"d":"4.42"},{"v":4.794417,"d":"4.79"},{"v":1.271019,"d":"1.27"},{"v":0.550822,"d":"0.55"},{"v":0.51114,"d":"0.51"},{"v":0.470097,"d":"0.47"},{"v":6.84546809228626,"d":"6.85"},{"v":2.77514919616989,"d":"2.78"},{"v":0.00676219207504377,"d":"0.01"},{"v":0.298869146090438,"d":"0.30"},"up","yes"]
[37996,0,"chr11","+",126355894,126414047,"ENST00000530591",11,1459,"ENSG00000110080","ST3GAL4","GO:0000139(Golgi membrane);GO:0003836(beta-galactoside (CMP) alpha-2,3-sialyltransferase activity);GO:0005576(extracellular region);GO:0005794(Golgi apparatus);GO:0006486(protein glycosylation);GO:0008373(sialyltransferase activity);GO:0009101(glycoprotein biosynthetic process);GO:0009247(glycolipid biosynthetic process);GO:0009312(oligosaccharide biosynthetic process);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016266(O-glycan processing);GO:0016740(transferase activity);GO:0016757(transferase activity, transferring glycosyl groups);GO:0018146(keratan sulfate biosynthetic process);GO:0030259(lipid glycosylation);GO:0032580(Golgi cisterna membrane);GO:0047288(monosialoganglioside sialyltransferase activity);GO:0050890(cognition);GO:0097503(sialylation);GO:1990743(protein sialylation)","00601(Glycosphingolipid biosynthesis - lacto and neolacto series)","NA","NA","ST3 beta-galactoside alpha-2,3-sialyltransferase 4 [Source:HGNC Symbol;Acc:HGNC:10864]",{"v":0.088877,"d":"0.09"},{"v":0.070946,"d":"0.07"},{"v":0.027332,"d":"0.03"},{"v":1.072016,"d":"1.07"},{"v":0.4917,"d":"0.49"},{"v":0.863078,"d":"0.86"},{"v":0.077120266491511,"d":"0.08"},{"v":-3.69674615292006,"d":"-3.70"},{"v":0.00677637554252754,"d":"0.01"},{"v":0.299132106269776,"d":"0.30"},"down","yes"]
[28076,0,"chr11","-",17788048,18012898,"ENST00000527494",11,1314,"ENSG00000129158","SERGEF","GO:0005085(guanyl-nucleotide exchange factor activity);GO:0005087(Ran guanyl-nucleotide exchange factor activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0007165(signal transduction);GO:0016235(aggresome);GO:0043231(intracellular membrane-bounded organelle);GO:0050709(negative regulation of protein secretion)","NA","K15421","NA","secretion regulating guanine nucleotide exchange factor [Source:HGNC Symbol;Acc:HGNC:17499]",{"v":0.19511,"d":"0.20"},{"v":0.332593,"d":"0.33"},0,{"v":2.226109,"d":"2.23"},{"v":1.870701,"d":"1.87"},{"v":2.9677,"d":"2.97"},{"v":0.0746977497377738,"d":"0.07"},{"v":-3.74279140714915,"d":"-3.74"},{"v":0.00684426382100989,"d":"0.01"},{"v":0.30176226288506,"d":"0.30"},"down","yes"]
[142515,0,"chr3","-",105658970,105868238,"ENST00000651978",19,3033,"ENSG00000114423","CBLB","GO:0001784(phosphotyrosine residue binding);GO:0004842(ubiquitin-protein transferase activity);GO:0005509(calcium ion binding);GO:0005515(protein binding);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0006607(NLS-bearing protein import into nucleus);GO:0007165(signal transduction);GO:0007166(cell surface receptor signaling pathway);GO:0007175(negative regulation of epidermal growth factor-activated receptor activity);GO:0008270(zinc ion binding);GO:0016567(protein ubiquitination);GO:0016740(transferase activity);GO:0017124(SH3 domain binding);GO:0023051(regulation of signaling);GO:0030971(receptor tyrosine kinase binding);GO:0045121(membrane raft);GO:0046872(metal ion binding);GO:0061630(ubiquitin protein ligase activity);GO:2000583(regulation of platelet-derived growth factor receptor-alpha signaling pathway)","04012(ErbB signaling pathway);04120(Ubiquitin mediated proteolysis);04144(Endocytosis);04625(C-type lectin receptor signaling pathway);04660(T cell receptor signaling pathway);04910(Insulin signaling pathway);05162(Measles)","NA","NA","Cbl proto-oncogene B [Source:HGNC Symbol;Acc:HGNC:1542]",{"v":0.419518,"d":"0.42"},{"v":0.43593,"d":"0.44"},{"v":0.004634,"d":"0.00"},{"v":0.012499,"d":"0.01"},{"v":0.004246,"d":"0.00"},{"v":0.009803,"d":"0.01"},{"v":32.3972427301492,"d":"32.40"},{"v":5.01779912809568,"d":"5.02"},{"v":0.00693775114312683,"d":"0.01"},{"v":0.305513332157331,"d":"0.31"},"up","yes"]
[131179,0,"chr21","-",45282369,45287891,"ENST00000493811",4,577,"ENSG00000186866","POFUT2","GO:0001707(mesoderm formation);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005794(Golgi apparatus);GO:0005975(carbohydrate metabolic process);GO:0006004(fucose metabolic process);GO:0006486(protein glycosylation);GO:0008417(fucosyltransferase activity);GO:0010468(regulation of gene expression);GO:0010717(regulation of epithelial to mesenchymal transition);GO:0016740(transferase activity);GO:0016757(transferase activity, transferring glycosyl groups);GO:0036065(fucosylation);GO:0036066(protein O-linked fucosylation);GO:0046922(peptide-O-fucosyltransferase activity);GO:0051046(regulation of secretion)","00514(Other types of O-glycan biosynthesis)","K03691","EC:2.4.1.221","protein O-fucosyltransferase 2 [Source:HGNC Symbol;Acc:HGNC:14683]",0,{"v":0.098679,"d":"0.10"},0,{"v":3.657853,"d":"3.66"},0,{"v":4.281449,"d":"4.28"},{"v":0.0124291782829271,"d":"0.01"},{"v":-6.33012526959773,"d":"-6.33"},{"v":0.00700493805478325,"d":"0.01"},{"v":0.308098546646823,"d":"0.31"},"down","yes"]
[78149,0,"chr16","+",82626965,83795376,"ENST00000268613",15,2722,"ENSG00000140945","CDH13","GO:0000278(mitotic cell cycle);GO:0000902(cell morphogenesis);GO:0001938(positive regulation of endothelial cell proliferation);GO:0001954(positive regulation of cell-matrix adhesion);GO:0002040(sprouting angiogenesis);GO:0005509(calcium ion binding);GO:0005576(extracellular region);GO:0005615(extracellular space);GO:0005737(cytoplasm);GO:0005886(plasma membrane);GO:0005901(caveola);GO:0005913(cell-cell adherens junction);GO:0005925(focal adhesion);GO:0007043(cell-cell junction assembly);GO:0007155(cell adhesion);GO:0007156(homophilic cell adhesion via plasma membrane adhesion molecules);GO:0007162(negative regulation of cell adhesion);GO:0007266(Rho protein signal transduction);GO:0008092(cytoskeletal protein binding);GO:0008285(negative regulation of cell population proliferation);GO:0009897(external side of plasma membrane);GO:0009986(cell surface);GO:0010033(response to organic substance);GO:0016020(membrane);GO:0016339(calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules);GO:0016342(catenin complex);GO:0016601(Rac protein signal transduction);GO:0030032(lamellipodium assembly);GO:0030100(regulation of endocytosis);GO:0030169(low-density lipoprotein particle binding);GO:0030335(positive regulation of cell migration);GO:0031225(anchored component of membrane);GO:0034332(adherens junction organization);GO:0042058(regulation of epidermal growth factor receptor signaling pathway);GO:0042803(protein homodimerization activity);GO:0043005(neuron projection);GO:0043542(endothelial cell migration);GO:0043616(keratinocyte proliferation);GO:0044331(cell-cell adhesion mediated by cadherin);GO:0045202(synapse);GO:0045296(cadherin binding);GO:0045944(positive regulation of transcription by RNA polymerase II);GO:0046872(metal ion binding);GO:0048471(perinuclear region of cytoplasm);GO:0048661(positive regulation of smooth muscle cell proliferation);GO:0050850(positive regulation of calcium-mediated signaling);GO:0050927(positive regulation of positive chemotaxis);GO:0051668(localization within membrane);GO:0055096(low-density lipoprotein particle mediated signaling);GO:0055100(adiponectin binding);GO:0062023(collagen-containing extracellular matrix);GO:0070062(extracellular exosome);GO:0071813(lipoprotein particle binding);GO:0098609(cell-cell adhesion);GO:0098982(GABA-ergic synapse)","NA","NA","NA","cadherin 13 [Source:HGNC Symbol;Acc:HGNC:1753]",{"v":0.374747,"d":"0.37"},{"v":0.002007,"d":"0.00"},{"v":0.333355,"d":"0.33"},{"v":23.106705,"d":"23.11"},{"v":0.210685,"d":"0.21"},{"v":0.057961,"d":"0.06"},{"v":0.0303785384869729,"d":"0.03"},{"v":-5.04080372639674,"d":"-5.04"},{"v":0.00705543138804531,"d":"0.01"},{"v":0.309944162427674,"d":"0.31"},"down","yes"]
[192297,0,"chr8","-",123320502,123416350,"ENST00000521903",29,5143,"ENSG00000156802","ATAD2","GO:0000166(nucleotide binding);GO:0003682(chromatin binding);GO:0005515(protein binding);GO:0005524(ATP binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0006325(chromatin organization);GO:0006355(regulation of transcription, DNA-templated);GO:0006357(regulation of transcription by RNA polymerase II);GO:0016787(hydrolase activity);GO:0016887(ATPase activity);GO:0031936(negative regulation of chromatin silencing);GO:0042393(histone binding);GO:0045893(positive regulation of transcription, DNA-templated);GO:0045944(positive regulation of transcription by RNA polymerase II);GO:0070062(extracellular exosome)","NA","K22531","EC:3.6.1.-","ATPase family, AAA domain containing 2 [Source:HGNC Symbol;Acc:HGNC:30123]",{"v":0.003011,"d":"0.00"},{"v":0.178362,"d":"0.18"},{"v":0.168179,"d":"0.17"},{"v":0.005201,"d":"0.01"},0,0,{"v":67.2086137281292,"d":"67.21"},{"v":6.07057424138061,"d":"6.07"},{"v":0.00706523273691375,"d":"0.01"},{"v":0.309999885666759,"d":"0.31"},"up","yes"]
[29069,0,"chr11","+",35138882,35177110,"ENST00000526025",2,1025,"ENSG00000026508","CD44","GO:0004888(transmembrane signaling receptor activity);GO:0004896(cytokine receptor activity);GO:0005515(protein binding);GO:0005518(collagen binding);GO:0005540(hyaluronic acid binding);GO:0005794(Golgi apparatus);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0005887(integral component of plasma membrane);GO:0005902(microvillus);GO:0005925(focal adhesion);GO:0006954(inflammatory response);GO:0007155(cell adhesion);GO:0007160(cell-matrix adhesion);GO:0009986(cell surface);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016323(basolateral plasma membrane);GO:0016324(apical plasma membrane);GO:0016477(cell migration);GO:0022617(extracellular matrix disassembly);GO:0030198(extracellular matrix organization);GO:0030214(hyaluronan catabolic process);GO:0030667(secretory granule membrane);GO:0031258(lamellipodium membrane);GO:0033138(positive regulation of peptidyl-serine phosphorylation);GO:0033674(positive regulation of kinase activity);GO:0034116(positive regulation of heterotypic cell-cell adhesion);GO:0035692(macrophage migration inhibitory factor receptor complex);GO:0042110(T cell activation);GO:0042995(cell projection);GO:0043066(negative regulation of apoptotic process);GO:0043154(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process);GO:0043312(neutrophil degranulation);GO:0043518(negative regulation of DNA damage response, signal transduction by p53 class mediator);GO:0044319(wound healing, spreading of cells);GO:0044344(cellular response to fibroblast growth factor stimulus);GO:0050731(positive regulation of peptidyl-tyrosine phosphorylation);GO:0050900(leukocyte migration);GO:0051216(cartilage development);GO:0060333(interferon-gamma-mediated signaling pathway);GO:0070062(extracellular exosome);GO:0070374(positive regulation of ERK1 and ERK2 cascade);GO:0070487(monocyte aggregation);GO:0098609(cell-cell adhesion);GO:1900625(positive regulation of monocyte aggregation);GO:1902166(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator);GO:2000392(regulation of lamellipodium morphogenesis)","04512(ECM-receptor interaction);04640(Hematopoietic cell lineage);05131(Shigellosis);05169(Epstein-Barr virus infection);05205(Proteoglycans in cancer);05206(MicroRNAs in cancer)","NA","NA","CD44 molecule (Indian blood group) [Source:HGNC Symbol;Acc:HGNC:1681]",{"v":0.631038,"d":"0.63"},{"v":0.500976,"d":"0.50"},{"v":2.690629,"d":"2.69"},{"v":8.985412,"d":"8.99"},{"v":8.479185,"d":"8.48"},{"v":10.752046,"d":"10.75"},{"v":0.135474762182021,"d":"0.14"},{"v":-2.88390398032751,"d":"-2.88"},{"v":0.0071104868729614,"d":"0.01"},{"v":0.311609153310842,"d":"0.31"},"down","yes"]
[11049,0,"chr1","-",150997100,151008375,"ENST00000361738",11,1961,"ENSG00000143409","MINDY1","GO:0004843(thiol-dependent ubiquitin-specific protease activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0006508(proteolysis);GO:0008150(biological_process);GO:0008233(peptidase activity);GO:0008234(cysteine-type peptidase activity);GO:0016604(nuclear body);GO:0016787(hydrolase activity);GO:0016807(cysteine-type carboxypeptidase activity);GO:0036435(K48-linked polyubiquitin modification-dependent protein binding);GO:0036459(thiol-dependent ubiquitinyl hydrolase activity);GO:0071108(protein K48-linked deubiquitination);GO:1990380(Lys48-specific deubiquitinase activity)","NA","K01309","EC:3.4.19.12","MINDY lysine 48 deubiquitinase 1 [Source:HGNC Symbol;Acc:HGNC:25648]",{"v":3.298508,"d":"3.30"},{"v":0.130757,"d":"0.13"},{"v":4.441821,"d":"4.44"},{"v":0.242915,"d":"0.24"},{"v":0.242807,"d":"0.24"},{"v":0.187062,"d":"0.19"},{"v":11.6992764393921,"d":"11.70"},{"v":3.548347401655,"d":"3.55"},{"v":0.00719679228188611,"d":"0.01"},{"v":0.314855704242041,"d":"0.31"},"up","yes"]
[48722,0,"chr12","-",120198556,120200864,"ENST00000546564",4,844,"ENSG00000089157","RPLP0","GO:0000027(ribosomal large subunit assembly);GO:0000184(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay);GO:0002181(cytoplasmic translation);GO:0003723(RNA binding);GO:0003735(structural constituent of ribosome);GO:0005515(protein binding);GO:0005622(intracellular);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005783(endoplasmic reticulum);GO:0005829(cytosol);GO:0005840(ribosome);GO:0005925(focal adhesion);GO:0006412(translation);GO:0006413(translational initiation);GO:0006614(SRP-dependent cotranslational protein targeting to membrane);GO:0014069(postsynaptic density);GO:0016020(membrane);GO:0019083(viral transcription);GO:0022625(cytosolic large ribosomal subunit);GO:0035722(interleukin-12-mediated signaling pathway);GO:0036464(cytoplasmic ribonucleoprotein granule);GO:0042254(ribosome biogenesis);GO:0070062(extracellular exosome);GO:0070180(large ribosomal subunit rRNA binding);GO:0098794(postsynapse);GO:1990904(ribonucleoprotein complex)","03010(Ribosome)","K02941","NA","ribosomal protein lateral stalk subunit P0 [Source:HGNC Symbol;Acc:HGNC:10371]",{"v":4.97335,"d":"4.97"},{"v":13.514791,"d":"13.51"},{"v":10.602038,"d":"10.60"},{"v":10.765755,"d":"10.77"},{"v":178.474213,"d":"178.47"},{"v":13.6019,"d":"13.60"},{"v":0.143413089648731,"d":"0.14"},{"v":-2.80175138668106,"d":"-2.80"},{"v":0.00720190174030102,"d":"0.01"},{"v":0.314855704242041,"d":"0.31"},"down","yes"]
[170793,0,"chr6","+",43431751,43450425,"ENST00000244533",20,5088,"ENSG00000124574","ABCC10","GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0005765(lysosomal membrane);GO:0005886(plasma membrane);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016887(ATPase activity);GO:0042626(ATPase activity, coupled to transmembrane movement of substances);GO:0055085(transmembrane transport)","02010(ABC transporters)","K05674","NA","ATP binding cassette subfamily C member 10 [Source:HGNC Symbol;Acc:HGNC:52]",{"v":0.015569,"d":"0.02"},{"v":0.041828,"d":"0.04"},0,{"v":0.442158,"d":"0.44"},{"v":0.539368,"d":"0.54"},{"v":0.091975,"d":"0.09"},{"v":0.0534671136775839,"d":"0.05"},{"v":-4.2252043921373,"d":"-4.23"},{"v":0.00722241940903086,"d":"0.01"},{"v":0.315321372937923,"d":"0.32"},"down","yes"]
[99668,0,"chr19","-",13104907,13116740,"ENST00000593157",16,2127,"ENSG00000104907","TRMT1","GO:0000049(tRNA binding);GO:0002940(tRNA N2-guanine methylation);GO:0003723(RNA binding);GO:0004809(tRNA (guanine-N2-)-methyltransferase activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0006400(tRNA modification);GO:0008033(tRNA processing);GO:0008168(methyltransferase activity);GO:0016740(transferase activity);GO:0030488(tRNA methylation);GO:0032259(methylation);GO:0046872(metal ion binding)","NA","K00555","2.1.1.216;EC:2.1.1.215","tRNA methyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:25980]",{"v":0.289316,"d":"0.29"},{"v":0.057209,"d":"0.06"},{"v":0.135604,"d":"0.14"},{"v":1.74845,"d":"1.75"},{"v":1.780773,"d":"1.78"},{"v":0.590853,"d":"0.59"},{"v":0.117019443330657,"d":"0.12"},{"v":-3.09517983459832,"d":"-3.10"},{"v":0.00724246068018019,"d":"0.01"},{"v":0.315321372937923,"d":"0.32"},"down","yes"]
[35628,0,"chr11","-",101451564,101584007,"ENST00000344327",13,4691,"ENSG00000137672","TRPC6","GO:0003779(actin binding);GO:0005216(ion channel activity);GO:0005261(cation channel activity);GO:0005262(calcium channel activity);GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0005886(plasma membrane);GO:0005887(integral component of plasma membrane);GO:0006811(ion transport);GO:0006812(cation transport);GO:0006816(calcium ion transport);GO:0006828(manganese ion transport);GO:0007204(positive regulation of cytosolic calcium ion concentration);GO:0007338(single fertilization);GO:0007568(aging);GO:0010800(positive regulation of peptidyl-threonine phosphorylation);GO:0015279(store-operated calcium channel activity);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0030168(platelet activation);GO:0030182(neuron differentiation);GO:0030276(clathrin binding);GO:0032414(positive regulation of ion transmembrane transporter activity);GO:0034703(cation channel complex);GO:0036057(slit diaphragm);GO:0042803(protein homodimerization activity);GO:0042805(actinin binding);GO:0045666(positive regulation of neuron differentiation);GO:0050774(negative regulation of dendrite morphogenesis);GO:0051117(ATPase binding);GO:0051480(regulation of cytosolic calcium ion concentration);GO:0051928(positive regulation of calcium ion transport);GO:0055085(transmembrane transport);GO:0070301(cellular response to hydrogen peroxide);GO:0070588(calcium ion transmembrane transport);GO:0070679(inositol 1,4,5 trisphosphate binding);GO:0071456(cellular response to hypoxia)","04022(cGMP-PKG signaling pathway);04360(Axon guidance)","K04969","NA","transient receptor potential cation channel subfamily C member 6 [Source:HGNC Symbol;Acc:HGNC:12338]",{"v":0.191954,"d":"0.19"},{"v":0.175332,"d":"0.18"},{"v":0.150778,"d":"0.15"},{"v":1.177557,"d":"1.18"},{"v":1.237604,"d":"1.24"},{"v":1.10643,"d":"1.11"},{"v":0.147110780326279,"d":"0.15"},{"v":-2.76502512325456,"d":"-2.77"},{"v":0.00724480358969386,"d":"0.01"},{"v":0.315321372937923,"d":"0.32"},"down","yes"]
[723,0,"chr1","+",2391890,2403751,"ENST00000378512",7,1404,"ENSG00000157916","RER1","GO:0000139(Golgi membrane);GO:0003674(molecular_function);GO:0005783(endoplasmic reticulum);GO:0005793(endoplasmic reticulum-Golgi intermediate compartment);GO:0005794(Golgi apparatus);GO:0005886(plasma membrane);GO:0006621(protein retention in ER lumen);GO:0006890(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum);GO:0007528(neuromuscular junction development);GO:0009986(cell surface);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0030173(integral component of Golgi membrane);GO:0033130(acetylcholine receptor binding);GO:0071340(skeletal muscle acetylcholine-gated channel clustering);GO:1903078(positive regulation of protein localization to plasma membrane)","NA","NA","NA","retention in endoplasmic reticulum sorting receptor 1 [Source:HGNC Symbol;Acc:HGNC:30309]",{"v":25.174652,"d":"25.17"},{"v":23.494305,"d":"23.49"},{"v":1.14175,"d":"1.14"},{"v":1.479082,"d":"1.48"},{"v":1.709529,"d":"1.71"},{"v":3.323248,"d":"3.32"},{"v":7.64922996643508,"d":"7.65"},{"v":2.93531452172413,"d":"2.94"},{"v":0.00724727075153223,"d":"0.01"},{"v":0.315321372937923,"d":"0.32"},"up","yes"]
[18980,0,"chr10","-",7559270,7666966,"ENST00000397146",14,6716,"ENSG00000123243","ITIH5","GO:0004867(serine-type endopeptidase inhibitor activity);GO:0010951(negative regulation of endopeptidase activity);GO:0030212(hyaluronan metabolic process)","NA","NA","NA","inter-alpha-trypsin inhibitor heavy chain family member 5 [Source:HGNC Symbol;Acc:HGNC:21449]",{"v":0.103575,"d":"0.10"},{"v":0.232297,"d":"0.23"},{"v":0.200936,"d":"0.20"},{"v":1.097553,"d":"1.10"},{"v":1.114237,"d":"1.11"},{"v":1.255803,"d":"1.26"},{"v":0.154807095296363,"d":"0.15"},{"v":-2.69145649863572,"d":"-2.69"},{"v":0.00725700818718748,"d":"0.01"},{"v":0.315367353397753,"d":"0.32"},"down","yes"]
[6593,0,"chr1","+",55039548,55064852,"ENST00000302118",12,3637,"ENSG00000169174","PCSK9","GO:0001822(kidney development);GO:0001889(liver development);GO:0001920(negative regulation of receptor recycling);GO:0002092(positive regulation of receptor internalization);GO:0003723(RNA binding);GO:0004252(serine-type endopeptidase activity);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0005615(extracellular space);GO:0005737(cytoplasm);GO:0005764(lysosome);GO:0005765(lysosomal membrane);GO:0005768(endosome);GO:0005769(early endosome);GO:0005770(late endosome);GO:0005783(endoplasmic reticulum);GO:0005788(endoplasmic reticulum lumen);GO:0005791(rough endoplasmic reticulum);GO:0005794(Golgi apparatus);GO:0005886(plasma membrane);GO:0006508(proteolysis);GO:0006629(lipid metabolic process);GO:0006641(triglyceride metabolic process);GO:0006644(phospholipid metabolic process);GO:0006915(apoptotic process);GO:0007041(lysosomal transport);GO:0008202(steroid metabolic process);GO:0008203(cholesterol metabolic process);GO:0008233(peptidase activity);GO:0008236(serine-type peptidase activity);GO:0009267(cellular response to starvation);GO:0009986(cell surface);GO:0010469(regulation of signaling receptor activity);GO:0010989(negative regulation of low-density lipoprotein particle clearance);GO:0016485(protein processing);GO:0016540(protein autoprocessing);GO:0016787(hydrolase activity);GO:0019871(sodium channel inhibitor activity);GO:0022008(neurogenesis);GO:0030134(COPII-coated ER to Golgi transport vesicle);GO:0030169(low-density lipoprotein particle binding);GO:0030182(neuron differentiation);GO:0030547(receptor inhibitor activity);GO:0031232(extrinsic component of external side of plasma membrane);GO:0032799(low-density lipoprotein receptor particle metabolic process);GO:0032802(low-density lipoprotein particle receptor catabolic process);GO:0032803(regulation of low-density lipoprotein particle receptor catabolic process);GO:0032805(positive regulation of low-density lipoprotein particle receptor catabolic process);GO:0032869(cellular response to insulin stimulus);GO:0034185(apolipoprotein binding);GO:0034189(very-low-density lipoprotein particle binding);GO:0034190(apolipoprotein receptor binding);GO:0034383(low-density lipoprotein particle clearance);GO:0036020(endolysosome membrane);GO:0042157(lipoprotein metabolic process);GO:0042632(cholesterol homeostasis);GO:0043523(regulation of neuron apoptotic process);GO:0043525(positive regulation of neuron apoptotic process);GO:0043621(protein self-association);GO:0043687(post-translational protein modification);GO:0044267(cellular protein metabolic process);GO:0048471(perinuclear region of cytoplasm);GO:0050750(low-density lipoprotein particle receptor binding);GO:0070326(very-low-density lipoprotein particle receptor binding);GO:1905596(negative regulation of low-density lipoprotein particle receptor binding);GO:1905598(negative regulation of low-density lipoprotein receptor activity);GO:1905601(negative regulation of receptor-mediated endocytosis involved in cholesterol transport);GO:1990666(PCSK9-LDLR complex);GO:1990667(PCSK9-AnxA2 complex);GO:2000272(negative regulation of signaling receptor activity);GO:2000650(negative regulation of sodium ion transmembrane transporter activity)","04979(Cholesterol metabolism)","K13050","EC:3.4.21.-","proprotein convertase subtilisin/kexin type 9 [Source:HGNC Symbol;Acc:HGNC:20001]",{"v":0.091891,"d":"0.09"},{"v":0.114822,"d":"0.11"},{"v":0.181209,"d":"0.18"},{"v":0.837016,"d":"0.84"},{"v":1.221827,"d":"1.22"},{"v":0.697791,"d":"0.70"},{"v":0.140723070237108,"d":"0.14"},{"v":-2.82906923050429,"d":"-2.83"},{"v":0.00732222137900244,"d":"0.01"},{"v":0.317488554279977,"d":"0.32"},"down","yes"]
[51157,0,"chr13","-",37562634,37598758,"ENST00000379742",21,3071,"ENSG00000133110","POSTN","GO:0001666(response to hypoxia);GO:0001953(negative regulation of cell-matrix adhesion);GO:0003073(regulation of systemic arterial blood pressure);GO:0005201(extracellular matrix structural constituent);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0005615(extracellular space);GO:0005737(cytoplasm);GO:0005794(Golgi apparatus);GO:0005802(trans-Golgi network);GO:0007155(cell adhesion);GO:0008201(heparin binding);GO:0008593(regulation of Notch signaling pathway);GO:0009612(response to mechanical stimulus);GO:0009888(tissue development);GO:0014850(response to muscle activity);GO:0014911(positive regulation of smooth muscle cell migration);GO:0030198(extracellular matrix organization);GO:0031012(extracellular matrix);GO:0031594(neuromuscular junction);GO:0032355(response to estradiol);GO:0042060(wound healing);GO:0044344(cellular response to fibroblast growth factor stimulus);GO:0046872(metal ion binding);GO:0050839(cell adhesion molecule binding);GO:0062023(collagen-containing extracellular matrix);GO:0071307(cellular response to vitamin K);GO:0071356(cellular response to tumor necrosis factor);GO:0071560(cellular response to transforming growth factor beta stimulus);GO:1900025(negative regulation of substrate adhesion-dependent cell spreading);GO:1904209(positive regulation of chemokine (C-C motif) ligand 2 secretion);GO:1990138(neuron projection extension);GO:1990523(bone regeneration)","NA","NA","NA","periostin [Source:HGNC Symbol;Acc:HGNC:16953]",{"v":166.011902,"d":"166.01"},{"v":181.978531,"d":"181.98"},{"v":161.83757,"d":"161.84"},{"v":52.398743,"d":"52.40"},{"v":53.340435,"d":"53.34"},{"v":52.05592,"d":"52.06"},{"v":3.23094956346489,"d":"3.23"},{"v":1.69195822967879,"d":"1.69"},{"v":0.00732792904262114,"d":"0.01"},{"v":0.317488554279977,"d":"0.32"},"up","yes"]
[107308,0,"chr19","-",52114790,52139746,"ENST00000330123",5,2563,"ENSG00000204611","ZNF616","GO:0000981(DNA-binding transcription factor activity, RNA polymerase II-specific);GO:0003676(nucleic acid binding);GO:0003677(DNA binding);GO:0005622(intracellular);GO:0005634(nucleus);GO:0006355(regulation of transcription, DNA-templated);GO:0006357(regulation of transcription by RNA polymerase II);GO:0046872(metal ion binding)","05168(Herpes simplex virus 1 infection)","K09228","NA","zinc finger protein 616 [Source:HGNC Symbol;Acc:HGNC:28062]",0,{"v":0.403282,"d":"0.40"},{"v":0.436602,"d":"0.44"},{"v":0.005022,"d":"0.01"},0,0,{"v":167.240939864596,"d":"167.24"},{"v":7.38578424598396,"d":"7.39"},{"v":0.00733203680266723,"d":"0.01"},{"v":0.317488554279977,"d":"0.32"},"up","yes"]
[35515,0,"chr11","+",95790513,95817903,"ENST00000544522",6,851,"ENSG00000166037","CEP57","GO:0000086(G2/M transition of mitotic cell cycle);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005794(Golgi apparatus);GO:0005813(centrosome);GO:0005815(microtubule organizing center);GO:0005829(cytosol);GO:0005856(cytoskeleton);GO:0005874(microtubule);GO:0007286(spermatid development);GO:0008017(microtubule binding);GO:0008543(fibroblast growth factor receptor signaling pathway);GO:0010389(regulation of G2/M transition of mitotic cell cycle);GO:0017134(fibroblast growth factor binding);GO:0034453(microtubule anchoring);GO:0042802(identical protein binding);GO:0042803(protein homodimerization activity);GO:0043015(gamma-tubulin binding);GO:0051260(protein homooligomerization);GO:0097711(ciliary basal body-plasma membrane docking)","NA","K16762","NA","centrosomal protein 57 [Source:HGNC Symbol;Acc:HGNC:30794]",{"v":3.446921,"d":"3.45"},{"v":4.634353,"d":"4.63"},{"v":2.910268,"d":"2.91"},{"v":0.647851,"d":"0.65"},{"v":0.084432,"d":"0.08"},{"v":0.531789,"d":"0.53"},{"v":8.69534488541792,"d":"8.70"},{"v":3.12024325060426,"d":"3.12"},{"v":0.00750039962084127,"d":"0.01"},{"v":0.324392283601385,"d":"0.32"},"up","yes"]
[24706,0,"chr10","+",119029714,119033730,"ENST00000425699",1,4017,"ENSG00000188613","NANOS1","GO:0001558(regulation of cell growth);GO:0001894(tissue homeostasis);GO:0003723(RNA binding);GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0006417(regulation of translation);GO:0008270(zinc ion binding);GO:0010608(posttranscriptional regulation of gene expression);GO:0010631(epithelial cell migration);GO:0016477(cell migration);GO:0017148(negative regulation of translation);GO:0030371(translation repressor activity);GO:0046872(metal ion binding);GO:0048471(perinuclear region of cytoplasm);GO:0098749(cerebellar neuron development);GO:1900153(positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)","NA","K18741","NA","nanos C2HC-type zinc finger 1 [Source:HGNC Symbol;Acc:HGNC:23044]",{"v":5.951038,"d":"5.95"},{"v":7.849747,"d":"7.85"},{"v":6.429754,"d":"6.43"},{"v":21.363197,"d":"21.36"},{"v":22.932474,"d":"22.93"},{"v":23.202311,"d":"23.20"},{"v":0.29972064942623,"d":"0.30"},{"v":-1.73830961230859,"d":"-1.74"},{"v":0.00754399073719616,"d":"0.01"},{"v":0.32588963553191,"d":"0.33"},"down","yes"]
[124681,0,"chr20","-",3162618,3173592,"ENST00000337576",5,4238,"ENSG00000088899","LZTS3","GO:0005737(cytoplasm);GO:0005856(cytoskeleton);GO:0005886(plasma membrane);GO:0014069(postsynaptic density);GO:0016020(membrane);GO:0030054(cell junction);GO:0045202(synapse);GO:0045211(postsynaptic membrane);GO:0061001(regulation of dendritic spine morphogenesis)","NA","NA","NA","leucine zipper tumor suppressor family member 3 [Source:HGNC Symbol;Acc:HGNC:30139]",{"v":0.078105,"d":"0.08"},{"v":0.004011,"d":"0.00"},0,{"v":1.175225,"d":"1.18"},{"v":0.015659,"d":"0.02"},{"v":1.123788,"d":"1.12"},{"v":0.0354763007458508,"d":"0.04"},{"v":-4.81700060780925,"d":"-4.82"},{"v":0.00759853375366586,"d":"0.01"},{"v":0.327631567320323,"d":"0.33"},"down","yes"]
[150327,0,"chr4","-",23795339,23881292,"ENST00000613098",12,3210,"ENSG00000109819","PPARGC1A","GO:0000302(response to reactive oxygen species);GO:0000422(autophagy of mitochondrion);GO:0001659(temperature homeostasis);GO:0001666(response to hypoxia);GO:0001678(cellular glucose homeostasis);GO:0001933(negative regulation of protein phosphorylation);GO:0002021(response to dietary excess);GO:0002931(response to ischemia);GO:0003676(nucleic acid binding);GO:0003677(DNA binding);GO:0003682(chromatin binding);GO:0003712(transcription coregulator activity);GO:0003713(transcription coactivator activity);GO:0003723(RNA binding);GO:0005102(signaling receptor binding);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005719(nuclear euchromatin);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0006012(galactose metabolic process);GO:0006094(gluconeogenesis);GO:0006355(regulation of transcription, DNA-templated);GO:0006367(transcription initiation from RNA polymerase II promoter);GO:0006397(mRNA processing);GO:0007005(mitochondrion organization);GO:0007568(aging);GO:0007586(digestion);GO:0007623(circadian rhythm);GO:0008134(transcription factor binding);GO:0008209(androgen metabolic process);GO:0008380(RNA splicing);GO:0009409(response to cold);GO:0009750(response to fructose);GO:0010628(positive regulation of gene expression);GO:0010822(positive regulation of mitochondrion organization);GO:0014070(response to organic cyclic compound);GO:0014732(skeletal muscle atrophy);GO:0014823(response to activity);GO:0014850(response to muscle activity);GO:0014878(response to electrical stimulus involved in regulation of muscle adaptation);GO:0014912(negative regulation of smooth muscle cell migration);GO:0016605(PML body);GO:0016922(nuclear receptor binding);GO:0019395(fatty acid oxidation);GO:0021549(cerebellum development);GO:0022626(cytosolic ribosome);GO:0022904(respiratory electron transport chain);GO:0030331(estrogen receptor binding);GO:0030374(nuclear receptor transcription coactivator activity);GO:0030521(androgen receptor signaling pathway);GO:0030900(forebrain development);GO:0031325(positive regulation of cellular metabolic process);GO:0031490(chromatin DNA binding);GO:0031625(ubiquitin protein ligase binding);GO:0031667(response to nutrient levels);GO:0032922(circadian regulation of gene expression);GO:0034599(cellular response to oxidative stress);GO:0035066(positive regulation of histone acetylation);GO:0035865(cellular response to potassium ion);GO:0042493(response to drug);GO:0042594(response to starvation);GO:0042752(regulation of circadian rhythm);GO:0042975(peroxisome proliferator activated receptor binding);GO:0043014(alpha-tubulin binding);GO:0043025(neuronal cell body);GO:0043201(response to leucine);GO:0043231(intracellular membrane-bounded organelle);GO:0043524(negative regulation of neuron apoptotic process);GO:0043565(sequence-specific DNA binding);GO:0045333(cellular respiration);GO:0045722(positive regulation of gluconeogenesis);GO:0045820(negative regulation of glycolytic process);GO:0045893(positive regulation of transcription, DNA-templated);GO:0045944(positive regulation of transcription by RNA polymerase II);GO:0046321(positive regulation of fatty acid oxidation);GO:0048511(rhythmic process);GO:0048661(positive regulation of smooth muscle cell proliferation);GO:0048662(negative regulation of smooth muscle cell proliferation);GO:0050681(androgen receptor binding);GO:0050821(protein stabilization);GO:0050873(brown fat cell differentiation);GO:0051091(positive regulation of DNA-binding transcription factor activity);GO:0051552(flavone metabolic process);GO:0051602(response to electrical stimulus);GO:0060612(adipose tissue development);GO:0065003(protein-containing complex assembly);GO:0071222(cellular response to lipopolysaccharide);GO:0071250(cellular response to nitrite);GO:0071313(cellular response to caffeine);GO:0071332(cellular response to fructose stimulus);GO:0071333(cellular response to glucose stimulus);GO:0071354(cellular response to interleukin-6);GO:0071356(cellular response to tumor necrosis factor);GO:0071372(cellular response to follicle-stimulating hormone stimulus);GO:0071392(cellular response to estradiol stimulus);GO:0071398(cellular response to fatty acid);GO:0071456(cellular response to hypoxia);GO:0071560(cellular response to transforming growth factor beta stimulus);GO:0071871(response to epinephrine);GO:0071873(response to norepinephrine);GO:0090258(negative regulation of mitochondrial fission);GO:0097009(energy homeostasis);GO:0097066(response to thyroid hormone);GO:0097067(cellular response to thyroid hormone stimulus);GO:0097440(apical dendrite);GO:0120162(positive regulation of cold-induced thermogenesis);GO:1901215(negative regulation of neuron death);GO:1901558(response to metformin);GO:1901857(positive regulation of cellular respiration);GO:1901860(positive regulation of mitochondrial DNA metabolic process);GO:1901863(positive regulation of muscle tissue development);GO:1903506(regulation of nucleic acid-templated transcription);GO:1904635(positive regulation of glomerular visceral epithelial cell apoptotic process);GO:1904637(cellular response to ionomycin);GO:1904639(cellular response to resveratrol);GO:1904640(response to methionine);GO:1990841(promoter-specific chromatin binding);GO:1990843(subsarcolemmal mitochondrion);GO:1990844(interfibrillar mitochondrion);GO:1990845(adaptive thermogenesis);GO:2000184(positive regulation of progesterone biosynthetic process);GO:2000272(negative regulation of signaling receptor activity);GO:2000310(regulation of NMDA receptor activity);GO:2001171(positive regulation of ATP biosynthetic process)","04152(AMPK signaling pathway);04211(Longevity regulating pathway);04371(Apelin signaling pathway);04714(Thermogenesis);04910(Insulin signaling pathway);04920(Adipocytokine signaling pathway);04922(Glucagon signaling pathway);04931(Insulin resistance);05016(Huntington disease)","K07202","NA","PPARG coactivator 1 alpha [Source:HGNC Symbol;Acc:HGNC:9237]",{"v":0.013081,"d":"0.01"},{"v":0.464469,"d":"0.46"},{"v":0.694326,"d":"0.69"},0,{"v":0.024241,"d":"0.02"},0,{"v":48.3427251351017,"d":"48.34"},{"v":5.59522689666447,"d":"5.60"},{"v":0.00760235098406366,"d":"0.01"},{"v":0.327631567320323,"d":"0.33"},"up","yes"]
[126538,0,"chr20","+",36092710,36230327,"ENST00000373950",21,3631,"ENSG00000088367","EPB41L1","GO:0003779(actin binding);GO:0005198(structural molecule activity);GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005856(cytoskeleton);GO:0005886(plasma membrane);GO:0008092(cytoskeletal protein binding);GO:0030866(cortical actin cytoskeleton organization);GO:0031032(actomyosin structure organization)","NA","NA","NA","erythrocyte membrane protein band 4.1 like 1 [Source:HGNC Symbol;Acc:HGNC:3378]",{"v":0.062475,"d":"0.06"},0,0,{"v":3.181559,"d":"3.18"},0,{"v":2.069861,"d":"2.07"},{"v":0.0118967822036706,"d":"0.01"},{"v":-6.39328477813781,"d":"-6.39"},{"v":0.00782374277910132,"d":"0.01"},{"v":0.336773193323165,"d":"0.34"},"down","yes"]
[138809,0,"chr3","+",42600682,42648735,"ENST00000429888",19,7325,"ENSG00000114857","NKTR","GO:0000413(protein peptidyl-prolyl isomerization);GO:0003755(peptidyl-prolyl cis-trans isomerase activity);GO:0005654(nucleoplasm);GO:0005739(mitochondrion);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0006457(protein folding);GO:0016018(cyclosporin A binding);GO:0016020(membrane);GO:0016853(isomerase activity);GO:0042026(protein refolding);GO:0051082(unfolded protein binding)","NA","K12740","NA","natural killer cell triggering receptor [Source:HGNC Symbol;Acc:HGNC:7833]",{"v":3.998603,"d":"4.00"},{"v":1.224641,"d":"1.22"},0,{"v":0.07534,"d":"0.08"},0,{"v":0.002774,"d":"0.00"},{"v":66.8669380648795,"d":"66.87"},{"v":6.0632211505978,"d":"6.06"},{"v":0.0078671166369758,"d":"0.01"},{"v":0.338239464403942,"d":"0.34"},"up","yes"]
[134118,0,"chr22","-",35744148,35840284,"ENST00000416721",13,1254,"ENSG00000100320","RBFOX2","GO:0000381(regulation of alternative mRNA splicing, via spliceosome);GO:0003676(nucleic acid binding);GO:0003714(transcription corepressor activity);GO:0003723(RNA binding);GO:0003729(mRNA binding);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0006397(mRNA processing);GO:0007399(nervous system development);GO:0008134(transcription factor binding);GO:0008380(RNA splicing);GO:0008543(fibroblast growth factor receptor signaling pathway);GO:0010724(regulation of definitive erythrocyte differentiation);GO:0016070(RNA metabolic process);GO:0021942(radial glia guided migration of Purkinje cell);GO:0030520(intracellular estrogen receptor signaling pathway);GO:0042127(regulation of cell population proliferation);GO:0043484(regulation of RNA splicing);GO:0045892(negative regulation of transcription, DNA-templated);GO:0048813(dendrite morphogenesis);GO:0050885(neuromuscular process controlling balance)","NA","K14946","NA","RNA binding fox-1 homolog 2 [Source:HGNC Symbol;Acc:HGNC:9906]",{"v":0.438635,"d":"0.44"},{"v":0.688709,"d":"0.69"},{"v":0.570443,"d":"0.57"},{"v":13.331949,"d":"13.33"},{"v":0.103342,"d":"0.10"},{"v":7.433221,"d":"7.43"},{"v":0.0813563995362966,"d":"0.08"},{"v":-3.61960035627828,"d":"-3.62"},{"v":0.0078849101659616,"d":"0.01"},{"v":0.338603766346791,"d":"0.34"},"down","yes"]
[53691,0,"chr13","+",114235061,114272675,"ENST00000375308",19,2034,"ENSG00000130177","CDC16","GO:0000278(mitotic cell cycle);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005680(anaphase-promoting complex);GO:0005737(cytoplasm);GO:0005813(centrosome);GO:0005815(microtubule organizing center);GO:0005819(spindle);GO:0005829(cytosol);GO:0005856(cytoskeleton);GO:0005876(spindle microtubule);GO:0006511(ubiquitin-dependent protein catabolic process);GO:0007049(cell cycle);GO:0007088(regulation of mitotic nuclear division);GO:0008283(cell population proliferation);GO:0016567(protein ubiquitination);GO:0031145(anaphase-promoting complex-dependent catabolic process);GO:0051301(cell division);GO:0070979(protein K11-linked ubiquitination);GO:1901990(regulation of mitotic cell cycle phase transition)","04110(Cell cycle);04114(Oocyte meiosis);04120(Ubiquitin mediated proteolysis);04914(Progesterone-mediated oocyte maturation);05166(Human T-cell leukemia virus 1 infection)","K03353","NA","cell division cycle 16 [Source:HGNC Symbol;Acc:HGNC:1720]",{"v":1.132517,"d":"1.13"},{"v":0.817866,"d":"0.82"},{"v":0.456653,"d":"0.46"},{"v":6.014713,"d":"6.01"},{"v":6.269062,"d":"6.27"},{"v":2.961075,"d":"2.96"},{"v":0.157891747049003,"d":"0.16"},{"v":-2.66299233092572,"d":"-2.66"},{"v":0.00793173100626944,"d":"0.01"},{"v":0.340212263822631,"d":"0.34"},"down","yes"]
[79583,0,"chr17","-",1517993,1562791,"ENST00000539476",11,3613,"ENSG00000174238","PITPNA","GO:0005548(phospholipid transporter activity);GO:0005622(intracellular);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0006629(lipid metabolic process);GO:0007409(axonogenesis);GO:0007601(visual perception);GO:0008289(lipid binding);GO:0008525(phosphatidylcholine transporter activity);GO:0008526(phosphatidylinositol transporter activity);GO:0015914(phospholipid transport);GO:0031210(phosphatidylcholine binding);GO:0035091(phosphatidylinositol binding);GO:0035722(interleukin-12-mediated signaling pathway);GO:0070062(extracellular exosome);GO:1901611(phosphatidylglycerol binding)","NA","NA","NA","phosphatidylinositol transfer protein alpha [Source:HGNC Symbol;Acc:HGNC:9001]",{"v":17.909781,"d":"17.91"},{"v":0.232713,"d":"0.23"},0,0,{"v":0.117597,"d":"0.12"},0,{"v":154.276843797036,"d":"154.28"},{"v":7.26937772643258,"d":"7.27"},{"v":0.00800984000194033,"d":"0.01"},{"v":0.343157414234071,"d":"0.34"},"up","yes"]
[28351,0,"chr11","+",20387558,20509294,"ENST00000330796",15,2530,"ENSG00000185238","PRMT3","GO:0003676(nucleic acid binding);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0006355(regulation of transcription, DNA-templated);GO:0006479(protein methylation);GO:0008168(methyltransferase activity);GO:0008469(histone-arginine N-methyltransferase activity);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016274(protein-arginine N-methyltransferase activity);GO:0016740(transferase activity);GO:0019919(peptidyl-arginine methylation, to asymmetrical-dimethyl arginine);GO:0031397(negative regulation of protein ubiquitination);GO:0032259(methylation);GO:0034969(histone arginine methylation);GO:0035242(protein-arginine omega-N asymmetric methyltransferase activity);GO:0043022(ribosome binding);GO:0046872(metal ion binding)","NA","K11436","EC:2.1.1.319","protein arginine methyltransferase 3 [Source:HGNC Symbol;Acc:HGNC:30163]",{"v":0.145606,"d":"0.15"},{"v":0.191494,"d":"0.19"},{"v":0.294416,"d":"0.29"},{"v":3.494921,"d":"3.49"},{"v":0.82146,"d":"0.82"},{"v":0.837868,"d":"0.84"},{"v":0.122523378284596,"d":"0.12"},{"v":-3.02887104347742,"d":"-3.03"},{"v":0.00802997410371562,"d":"0.01"},{"v":0.343614792918714,"d":"0.34"},"down","yes"]
[103054,0,"chr19","+",36916332,36952734,"ENST00000333987",7,4096,"ENSG00000198453","ZNF568","GO:0000122(negative regulation of transcription by RNA polymerase II);GO:0000976(transcription regulatory region sequence-specific DNA binding);GO:0000981(DNA-binding transcription factor activity, RNA polymerase II-specific);GO:0001701(in utero embryonic development);GO:0003676(nucleic acid binding);GO:0003677(DNA binding);GO:0005622(intracellular);GO:0005634(nucleus);GO:0006355(regulation of transcription, DNA-templated);GO:0007275(multicellular organism development);GO:0045892(negative regulation of transcription, DNA-templated);GO:0046872(metal ion binding);GO:0060669(embryonic placenta morphogenesis)","05168(Herpes simplex virus 1 infection)","K09228","NA","zinc finger protein 568 [Source:HGNC Symbol;Acc:HGNC:25392]",{"v":0.009368,"d":"0.01"},{"v":0.009368,"d":"0.01"},{"v":0.043174,"d":"0.04"},{"v":0.222865,"d":"0.22"},{"v":0.285208,"d":"0.29"},{"v":0.325713,"d":"0.33"},{"v":0.07425166649476,"d":"0.07"},{"v":-3.75143278383781,"d":"-3.75"},{"v":0.00804677112804674,"d":"0.01"},{"v":0.343704776931359,"d":"0.34"},"down","yes"]
[47997,0,"chr12","-",110720921,110732983,"ENST00000546933",6,2154,"ENSG00000186298","PPP1CC","GO:0000164(protein phosphatase type 1 complex);GO:0000775(chromosome, centromeric region);GO:0000776(kinetochore);GO:0000777(condensed chromosome kinetochore);GO:0000784(nuclear chromosome, telomeric region);GO:0003723(RNA binding);GO:0004721(phosphoprotein phosphatase activity);GO:0004722(protein serine/threonine phosphatase activity);GO:0005515(protein binding);GO:0005521(lamin binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005694(chromosome);GO:0005730(nucleolus);GO:0005737(cytoplasm);GO:0005739(mitochondrion);GO:0005741(mitochondrial outer membrane);GO:0005829(cytosol);GO:0005925(focal adhesion);GO:0005975(carbohydrate metabolic process);GO:0005977(glycogen metabolic process);GO:0006470(protein dephosphorylation);GO:0007049(cell cycle);GO:0008022(protein C-terminus binding);GO:0008157(protein phosphatase 1 binding);GO:0016607(nuclear speck);GO:0016787(hydrolase activity);GO:0016791(phosphatase activity);GO:0019901(protein kinase binding);GO:0019903(protein phosphatase binding);GO:0019904(protein domain specific binding);GO:0030182(neuron differentiation);GO:0030496(midbody);GO:0032154(cleavage furrow);GO:0032922(circadian regulation of gene expression);GO:0032991(protein-containing complex);GO:0042752(regulation of circadian rhythm);GO:0043153(entrainment of circadian clock by photoperiod);GO:0043197(dendritic spine);GO:0044877(protein-containing complex binding);GO:0046822(regulation of nucleocytoplasmic transport);GO:0046872(metal ion binding);GO:0047485(protein N-terminus binding);GO:0048511(rhythmic process);GO:0051301(cell division);GO:0060252(positive regulation of glial cell proliferation);GO:0072357(PTW/PP1 phosphatase complex);GO:0098793(presynapse);GO:0098794(postsynapse);GO:0098978(glutamatergic synapse)","03015(mRNA surveillance pathway);04022(cGMP-PKG signaling pathway);04024(cAMP signaling pathway);04114(Oocyte meiosis);04218(Cellular senescence);04261(Adrenergic signaling in cardiomyocytes);04270(Vascular smooth muscle contraction);04390(Hippo signaling pathway);04510(Focal adhesion);04611(Platelet activation);04720(Long-term potentiation);04728(Dopaminergic synapse);04750(Inflammatory mediator regulation of TRP channels);04810(Regulation of actin cytoskeleton);04910(Insulin signaling pathway);04921(Oxytocin signaling pathway);04931(Insulin resistance);05031(Amphetamine addiction);05034(Alcoholism);05168(Herpes simplex virus 1 infection);05205(Proteoglycans in cancer)","NA","NA","protein phosphatase 1 catalytic subunit gamma [Source:HGNC Symbol;Acc:HGNC:9283]",{"v":0.81729,"d":"0.82"},{"v":11.30484,"d":"11.30"},{"v":16.181137,"d":"16.18"},{"v":0.953466,"d":"0.95"},{"v":1.991736,"d":"1.99"},{"v":0.751318,"d":"0.75"},{"v":7.65673308950039,"d":"7.66"},{"v":2.93672896644284,"d":"2.94"},{"v":0.00805099821548545,"d":"0.01"},{"v":0.343704776931359,"d":"0.34"},"up","yes"]
[143964,0,"chr3","-",128064785,128153914,"ENST00000464873",10,2126,"ENSG00000175792","RUVBL1","GO:0000166(nucleotide binding);GO:0000812(Swr1 complex);GO:0001094(TFIID-class transcription factor complex binding);GO:0003678(DNA helicase activity);GO:0003713(transcription coactivator activity);GO:0004003(ATP-dependent DNA helicase activity);GO:0004386(helicase activity);GO:0005515(protein binding);GO:0005524(ATP binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0005815(microtubule organizing center);GO:0005829(cytosol);GO:0005856(cytoskeleton);GO:0006281(DNA repair);GO:0006310(DNA recombination);GO:0006325(chromatin organization);GO:0006338(chromatin remodeling);GO:0006357(regulation of transcription by RNA polymerase II);GO:0006974(cellular response to DNA damage stimulus);GO:0007049(cell cycle);GO:0007283(spermatogenesis);GO:0016020(membrane);GO:0016363(nuclear matrix);GO:0016573(histone acetylation);GO:0016579(protein deubiquitination);GO:0016787(hydrolase activity);GO:0016887(ATPase activity);GO:0017025(TBP-class protein binding);GO:0031011(Ino80 complex);GO:0032508(DNA duplex unwinding);GO:0034080(CENP-A containing nucleosome assembly);GO:0035267(NuA4 histone acetyltransferase complex);GO:0040008(regulation of growth);GO:0043141(ATP-dependent 5'-3' DNA helicase activity);GO:0043531(ADP binding);GO:0043967(histone H4 acetylation);GO:0043968(histone H2A acetylation);GO:0045296(cadherin binding);GO:0051117(ATPase binding);GO:0051301(cell division);GO:0070062(extracellular exosome);GO:0071339(MLL1 complex);GO:0090263(positive regulation of canonical Wnt signaling pathway);GO:0097255(R2TP complex);GO:1903508(positive regulation of nucleic acid-templated transcription);GO:1904837(beta-catenin-TCF complex assembly);GO:1904874(positive regulation of telomerase RNA localization to Cajal body);GO:1990904(ribonucleoprotein complex)","04310(Wnt signaling pathway)","K04499","NA","RuvB like AAA ATPase 1 [Source:HGNC Symbol;Acc:HGNC:10474]",{"v":1.775796,"d":"1.78"},{"v":1.426045,"d":"1.43"},{"v":2.877214,"d":"2.88"},{"v":0.255303,"d":"0.26"},{"v":0.405608,"d":"0.41"},{"v":0.088309,"d":"0.09"},{"v":8.11384506553482,"d":"8.11"},{"v":3.02038575443984,"d":"3.02"},{"v":0.0080976906155565,"d":"0.01"},{"v":0.345292370966159,"d":"0.35"},"up","yes"]
[86718,0,"chr17","+",45894382,46028334,"ENST00000344290",15,6816,"ENSG00000186868","MAPT","GO:0000226(microtubule cytoskeleton organization);GO:0001774(microglial cell activation);GO:0003677(DNA binding);GO:0003680(AT DNA binding);GO:0003690(double-stranded DNA binding);GO:0003697(single-stranded DNA binding);GO:0003723(RNA binding);GO:0003779(actin binding);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0005623(cell);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005739(mitochondrion);GO:0005829(cytosol);GO:0005856(cytoskeleton);GO:0005874(microtubule);GO:0005886(plasma membrane);GO:0006475(internal protein amino acid acetylation);GO:0006919(activation of cysteine-type endopeptidase activity involved in apoptotic process);GO:0007267(cell-cell signaling);GO:0007613(memory);GO:0008017(microtubule binding);GO:0010288(response to lead ion);GO:0010469(regulation of signaling receptor activity);GO:0010506(regulation of autophagy);GO:0010629(negative regulation of gene expression);GO:0010917(negative regulation of mitochondrial membrane potential);GO:0015630(microtubule cytoskeleton);GO:0015631(tubulin binding);GO:0016020(membrane);GO:0016072(rRNA metabolic process);GO:0016607(nuclear speck);GO:0017124(SH3 domain binding);GO:0019896(axonal transport of mitochondrion);GO:0019899(enzyme binding);GO:0019901(protein kinase binding);GO:0021954(central nervous system neuron development);GO:0030424(axon);GO:0030425(dendrite);GO:0030426(growth cone);GO:0030673(axolemma);GO:0030674(protein binding, bridging);GO:0031110(regulation of microtubule polymerization or depolymerization);GO:0031113(regulation of microtubule polymerization);GO:0031116(positive regulation of microtubule polymerization);GO:0031122(cytoplasmic microtubule organization);GO:0031175(neuron projection development);GO:0032930(positive regulation of superoxide anion generation);GO:0033044(regulation of chromosome organization);GO:0033673(negative regulation of kinase activity);GO:0034063(stress granule assembly);GO:0034185(apolipoprotein binding);GO:0034399(nuclear periphery);GO:0034452(dynactin binding);GO:0034605(cellular response to heat);GO:0034614(cellular response to reactive oxygen species);GO:0035091(phosphatidylinositol binding);GO:0036464(cytoplasmic ribonucleoprotein granule);GO:0036477(somatodendritic compartment);GO:0042802(identical protein binding);GO:0042803(protein homodimerization activity);GO:0042995(cell projection);GO:0043005(neuron projection);GO:0043025(neuronal cell body);GO:0043197(dendritic spine);GO:0043565(sequence-specific DNA binding);GO:0044297(cell body);GO:0044304(main axon);GO:0045121(membrane raft);GO:0045298(tubulin complex);GO:0045773(positive regulation of axon extension);GO:0046785(microtubule polymerization);GO:0048018(receptor ligand activity);GO:0048143(astrocyte activation);GO:0048167(regulation of synaptic plasticity);GO:0048312(intracellular distribution of mitochondria);GO:0048699(generation of neurons);GO:0050808(synapse organization);GO:0050848(regulation of calcium-mediated signaling);GO:0051087(chaperone binding);GO:0051258(protein polymerization);GO:0051259(protein complex oligomerization);GO:0051721(protein phosphatase 2A binding);GO:0051879(Hsp90 protein binding);GO:0061564(axon development);GO:0070507(regulation of microtubule cytoskeleton organization);GO:0071813(lipoprotein particle binding);GO:0072386(plus-end-directed organelle transport along microtubule);GO:0090140(regulation of mitochondrial fission);GO:0090258(negative regulation of mitochondrial fission);GO:0097386(glial cell projection);GO:0097418(neurofibrillary tangle);GO:0097435(supramolecular fiber organization);GO:0098930(axonal transport);GO:0099077(histone-dependent DNA binding);GO:0099609(microtubule lateral binding);GO:1900034(regulation of cellular response to heat);GO:1900452(regulation of long-term synaptic depression);GO:1901216(positive regulation of neuron death);GO:1902474(positive regulation of protein localization to synapse);GO:1902936(phosphatidylinositol bisphosphate binding);GO:1902988(neurofibrillary tangle assembly);GO:1903748(negative regulation of establishment of protein localization to mitochondrion);GO:1903829(positive regulation of cellular protein localization);GO:1904115(axon cytoplasm);GO:1904428(negative regulation of tubulin deacetylation);GO:1905689(positive regulation of diacylglycerol kinase activity);GO:1990000(amyloid fibril formation);GO:1990090(cellular response to nerve growth factor stimulus);GO:1990416(cellular response to brain-derived neurotrophic factor stimulus);GO:2001020(regulation of response to DNA damage stimulus)","04010(MAPK signaling pathway);05010(Alzheimer disease)","K04380","NA","microtubule associated protein tau [Source:HGNC Symbol;Acc:HGNC:6893]",{"v":0.040671,"d":"0.04"},{"v":0.026795,"d":"0.03"},{"v":0.042601,"d":"0.04"},{"v":0.353034,"d":"0.35"},{"v":0.556899,"d":"0.56"},{"v":0.053373,"d":"0.05"},{"v":0.114259643353202,"d":"0.11"},{"v":-3.12961216303306,"d":"-3.13"},{"v":0.00815229313801568,"d":"0.01"},{"v":0.347203803541603,"d":"0.35"},"down","yes"]
[51153,0,"chr13","-",37562585,37598761,"ENST00000379749",22,3210,"ENSG00000133110","POSTN","GO:0001666(response to hypoxia);GO:0001953(negative regulation of cell-matrix adhesion);GO:0003073(regulation of systemic arterial blood pressure);GO:0005201(extracellular matrix structural constituent);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0005615(extracellular space);GO:0005737(cytoplasm);GO:0005794(Golgi apparatus);GO:0005802(trans-Golgi network);GO:0007155(cell adhesion);GO:0008201(heparin binding);GO:0008593(regulation of Notch signaling pathway);GO:0009612(response to mechanical stimulus);GO:0009888(tissue development);GO:0014850(response to muscle activity);GO:0014911(positive regulation of smooth muscle cell migration);GO:0030198(extracellular matrix organization);GO:0031012(extracellular matrix);GO:0031594(neuromuscular junction);GO:0032355(response to estradiol);GO:0042060(wound healing);GO:0044344(cellular response to fibroblast growth factor stimulus);GO:0046872(metal ion binding);GO:0050839(cell adhesion molecule binding);GO:0062023(collagen-containing extracellular matrix);GO:0071307(cellular response to vitamin K);GO:0071356(cellular response to tumor necrosis factor);GO:0071560(cellular response to transforming growth factor beta stimulus);GO:1900025(negative regulation of substrate adhesion-dependent cell spreading);GO:1904209(positive regulation of chemokine (C-C motif) ligand 2 secretion);GO:1990138(neuron projection extension);GO:1990523(bone regeneration)","NA","NA","NA","periostin [Source:HGNC Symbol;Acc:HGNC:16953]",{"v":11.773846,"d":"11.77"},{"v":10.591202,"d":"10.59"},{"v":14.637703,"d":"14.64"},{"v":3.937938,"d":"3.94"},{"v":1.675476,"d":"1.68"},{"v":3.482695,"d":"3.48"},{"v":4.06797576854015,"d":"4.07"},{"v":2.02431108560862,"d":"2.02"},{"v":0.00816163083469664,"d":"0.01"},{"v":0.347203803541603,"d":"0.35"},"up","yes"]
[17725,0,"chr1","+",235367413,235449078,"ENST00000406207",17,2071,"ENSG00000284770","TBCE","GO:0000226(microtubule cytoskeleton organization);GO:0003735(structural constituent of ribosome);GO:0005515(protein binding);GO:0005622(intracellular);GO:0005737(cytoplasm);GO:0005840(ribosome);GO:0005856(cytoskeleton);GO:0005874(microtubule);GO:0006412(translation);GO:0006457(protein folding);GO:0007023(post-chaperonin tubulin folding pathway);GO:0007052(mitotic spindle organization);GO:0051087(chaperone binding)","NA","K21768","NA","tubulin folding cofactor E [Source:HGNC Symbol;Acc:HGNC:11582]",0,{"v":0.487144,"d":"0.49"},{"v":0.469558,"d":"0.47"},0,0,{"v":0.009495,"d":"0.01"},{"v":100.75850447604,"d":"100.76"},{"v":6.65475780369024,"d":"6.65"},{"v":0.00824144947419344,"d":"0.01"},{"v":0.350189309236781,"d":"0.35"},"up","yes"]
[194433,0,"chr9","-",5786643,5833055,"ENST00000489219",16,3293,"ENSG00000099219","ERMP1","GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0006508(proteolysis);GO:0008233(peptidase activity);GO:0008237(metallopeptidase activity);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016787(hydrolase activity);GO:0046872(metal ion binding)","NA","NA","NA","endoplasmic reticulum metallopeptidase 1 [Source:HGNC Symbol;Acc:HGNC:23703]",{"v":0.05691,"d":"0.06"},{"v":0.431054,"d":"0.43"},{"v":0.309312,"d":"0.31"},{"v":0.019107,"d":"0.02"},{"v":0.014113,"d":"0.01"},0,{"v":23.9998795906081,"d":"24.00"},{"v":4.58495526261831,"d":"4.58"},{"v":0.00831761075145079,"d":"0.01"},{"v":0.353012615187158,"d":"0.35"},"up","yes"]
[40704,0,"chr12","+",19322518,19376397,"ENST00000538972",10,2072,"ENSG00000052126","PLEKHA5","GO:0005515(protein binding);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0008150(biological_process);GO:0010314(phosphatidylinositol-5-phosphate binding);GO:0014069(postsynaptic density);GO:0016020(membrane);GO:0032266(phosphatidylinositol-3-phosphate binding);GO:0061458(reproductive system development);GO:0070273(phosphatidylinositol-4-phosphate binding);GO:0080025(phosphatidylinositol-3,5-bisphosphate binding);GO:0098978(glutamatergic synapse)","NA","NA","NA","pleckstrin homology domain containing A5 [Source:HGNC Symbol;Acc:HGNC:30036]",0,{"v":9.772151,"d":"9.77"},{"v":11.829414,"d":"11.83"},{"v":0.255677,"d":"0.26"},0,{"v":0.207062,"d":"0.21"},{"v":46.6819632665498,"d":"46.68"},{"v":5.5447933314972,"d":"5.54"},{"v":0.0083308120894616,"d":"0.01"},{"v":0.353160330466908,"d":"0.35"},"up","yes"]
[195493,0,"chr9","-",35088689,35096601,"ENST00000361778",12,2464,"ENSG00000165282","PIGO","GO:0003824(catalytic activity);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0006506(GPI anchor biosynthetic process);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016740(transferase activity);GO:0016772(transferase activity, transferring phosphorus-containing groups);GO:0051377(mannose-ethanolamine phosphotransferase activity)","00563(Glycosylphosphatidylinositol (GPI)-anchor biosynthesis)","K05288","NA","phosphatidylinositol glycan anchor biosynthesis class O [Source:HGNC Symbol;Acc:HGNC:23215]",{"v":2.547125,"d":"2.55"},{"v":1.688876,"d":"1.69"},{"v":0.938844,"d":"0.94"},{"v":0.195722,"d":"0.20"},0,0,{"v":26.4397717170272,"d":"26.44"},{"v":4.72463781544951,"d":"4.72"},{"v":0.00834128275584207,"d":"0.01"},{"v":0.353169211371555,"d":"0.35"},"up","yes"]
[111937,0,"chr2","-",44318763,44361561,"ENST00000409957",14,4703,"ENSG00000138078","PREPL","GO:0004252(serine-type endopeptidase activity);GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0005794(Golgi apparatus);GO:0005829(cytosol);GO:0005856(cytoskeleton);GO:0006508(proteolysis);GO:0008233(peptidase activity);GO:0008236(serine-type peptidase activity);GO:0016787(hydrolase activity);GO:0070008(serine-type exopeptidase activity);GO:2000300(regulation of synaptic vesicle exocytosis)","NA","K22582","EC:3.4.21.-","prolyl endopeptidase like [Source:HGNC Symbol;Acc:HGNC:30228]",{"v":0.299106,"d":"0.30"},{"v":9.346718,"d":"9.35"},{"v":0.205141,"d":"0.21"},{"v":0.346242,"d":"0.35"},{"v":0.239878,"d":"0.24"},{"v":0.177764,"d":"0.18"},{"v":12.8958912609768,"d":"12.90"},{"v":3.68883957901547,"d":"3.69"},{"v":0.00835046387470867,"d":"0.01"},{"v":0.353169211371555,"d":"0.35"},"up","yes"]
[146431,0,"chr3","+",170357715,170396835,"ENST00000259119",7,7155,"ENSG00000136603","SKIL","GO:0000122(negative regulation of transcription by RNA polymerase II);GO:0000978(RNA polymerase II proximal promoter sequence-specific DNA binding);GO:0000981(DNA-binding transcription factor activity, RNA polymerase II-specific);GO:0001227(DNA-binding transcription repressor activity, RNA polymerase II-specific);GO:0001669(acrosomal vesicle);GO:0001825(blastocyst formation);GO:0002260(lymphocyte homeostasis);GO:0003682(chromatin binding);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0007050(cell cycle arrest);GO:0007179(transforming growth factor beta receptor signaling pathway);GO:0007283(spermatogenesis);GO:0030512(negative regulation of transforming growth factor beta receptor signaling pathway);GO:0030514(negative regulation of BMP signaling pathway);GO:0032991(protein-containing complex);GO:0034097(response to cytokine);GO:0045596(negative regulation of cell differentiation);GO:0046332(SMAD binding);GO:0048666(neuron development);GO:0050772(positive regulation of axonogenesis);GO:0070306(lens fiber cell differentiation);GO:1902043(positive regulation of extrinsic apoptotic signaling pathway via death domain receptors);GO:1902231(positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage)","04550(Signaling pathways regulating pluripotency of stem cells)","NA","NA","SKI like proto-oncogene [Source:HGNC Symbol;Acc:HGNC:10897]",0,{"v":0.0371,"d":"0.04"},0,{"v":1.37871,"d":"1.38"},{"v":1.613675,"d":"1.61"},0,{"v":0.0123981372717749,"d":"0.01"},{"v":-6.33373280711741,"d":"-6.33"},{"v":0.00838552578357213,"d":"0.01"},{"v":0.354045533015896,"d":"0.35"},"down","yes"]
[55813,0,"chr14","-",34562409,34630183,"ENST00000362031",14,2001,"ENSG00000129515","SNX6","GO:0005515(protein binding);GO:0005623(cell);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005764(lysosome);GO:0005768(endosome);GO:0005769(early endosome);GO:0005829(cytosol);GO:0006886(intracellular protein transport);GO:0007175(negative regulation of epidermal growth factor-activated receptor activity);GO:0008289(lipid binding);GO:0015031(protein transport);GO:0016020(membrane);GO:0016241(regulation of macroautophagy);GO:0030512(negative regulation of transforming growth factor beta receptor signaling pathway);GO:0030904(retromer complex);GO:0030905(retromer, tubulation complex);GO:0031410(cytoplasmic vesicle);GO:0031901(early endosome membrane);GO:0034452(dynactin binding);GO:0034713(type I transforming growth factor beta receptor binding);GO:0035091(phosphatidylinositol binding);GO:0042147(retrograde transport, endosome to Golgi);GO:0042803(protein homodimerization activity);GO:0043524(negative regulation of neuron apoptotic process);GO:0045892(negative regulation of transcription, DNA-templated);GO:0046982(protein heterodimerization activity);GO:0071364(cellular response to epidermal growth factor stimulus);GO:0097422(tubular endosome);GO:1904646(cellular response to amyloid-beta)","04144(Endocytosis)","K17920","NA","sorting nexin 6 [Source:HGNC Symbol;Acc:HGNC:14970]",{"v":0.000108,"d":"0.00"},{"v":0.326091,"d":"0.33"},{"v":0.722509,"d":"0.72"},{"v":33.632099,"d":"33.63"},{"v":0.03029,"d":"0.03"},{"v":0.448062,"d":"0.45"},{"v":0.0307444776968795,"d":"0.03"},{"v":-5.02352889199917,"d":"-5.02"},{"v":0.00839067448187963,"d":"0.01"},{"v":0.354045533015896,"d":"0.35"},"down","yes"]
[184286,0,"chr7","+",136869122,137017024,"ENST00000401861",5,2571,"ENSG00000181072","CHRM2","GO:0004930(G protein-coupled receptor activity);GO:0004993(G protein-coupled serotonin receptor activity);GO:0005886(plasma membrane);GO:0005887(integral component of plasma membrane);GO:0006940(regulation of smooth muscle contraction);GO:0007165(signal transduction);GO:0007186(G protein-coupled receptor signaling pathway);GO:0007187(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger);GO:0007188(adenylate cyclase-modulating G protein-coupled receptor signaling pathway);GO:0007197(adenylate cyclase-inhibiting G protein-coupled acetylcholine receptor signaling pathway);GO:0007207(phospholipase C-activating G protein-coupled acetylcholine receptor signaling pathway);GO:0007213(G protein-coupled acetylcholine receptor signaling pathway);GO:0007268(chemical synaptic transmission);GO:0007399(nervous system development);GO:0008016(regulation of heart contraction);GO:0009615(response to virus);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016907(G protein-coupled acetylcholine receptor activity);GO:0030054(cell junction);GO:0030425(dendrite);GO:0030594(neurotransmitter receptor activity);GO:0030665(clathrin-coated vesicle membrane);GO:0032279(asymmetric synapse);GO:0032280(symmetric synapse);GO:0043025(neuronal cell body);GO:0043679(axon terminus);GO:0045202(synapse);GO:0045211(postsynaptic membrane);GO:0061024(membrane organization);GO:0098664(G protein-coupled serotonin receptor signaling pathway);GO:0098978(glutamatergic synapse);GO:0098981(cholinergic synapse);GO:0099055(integral component of postsynaptic membrane);GO:0099056(integral component of presynaptic membrane);GO:1990763(arrestin family protein binding);GO:2000300(regulation of synaptic vesicle exocytosis)","04020(Calcium signaling pathway);04024(cAMP signaling pathway);04080(Neuroactive ligand-receptor interaction);04151(PI3K-Akt signaling pathway);04725(Cholinergic synapse);04810(Regulation of actin cytoskeleton)","NA","NA","cholinergic receptor muscarinic 2 [Source:HGNC Symbol;Acc:HGNC:1951]",{"v":0.026143,"d":"0.03"},{"v":0.015235,"d":"0.02"},{"v":0.517545,"d":"0.52"},{"v":2.077817,"d":"2.08"},{"v":3.747065,"d":"3.75"},{"v":1.250706,"d":"1.25"},{"v":0.0789931522298924,"d":"0.08"},{"v":-3.66212859562637,"d":"-3.66"},{"v":0.00844592730330586,"d":"0.01"},{"v":0.355963502237937,"d":"0.36"},"down","yes"]
[175292,0,"chr6","-",158109519,158168262,"ENST00000647468",17,3936,"ENSG00000122335","SERAC1","GO:0003674(molecular_function);GO:0005739(mitochondrion);GO:0005783(endoplasmic reticulum);GO:0006629(lipid metabolic process);GO:0008654(phospholipid biosynthetic process);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0030198(extracellular matrix organization);GO:0031012(extracellular matrix);GO:0032367(intracellular cholesterol transport);GO:0036148(phosphatidylglycerol acyl-chain remodeling);GO:0044233(mitochondria-associated endoplasmic reticulum membrane)","NA","NA","NA","serine active site containing 1 [Source:HGNC Symbol;Acc:HGNC:21061]",{"v":0.014254,"d":"0.01"},{"v":0.13598,"d":"0.14"},{"v":0.010246,"d":"0.01"},{"v":2.475474,"d":"2.48"},{"v":0.039971,"d":"0.04"},{"v":0.317727,"d":"0.32"},{"v":0.0566432253318895,"d":"0.06"},{"v":-4.14195277326199,"d":"-4.14"},{"v":0.00853704027520701,"d":"0.01"},{"v":0.359206750816378,"d":"0.36"},"down","yes"]
[94495,0,"chr18","-",46827758,46917474,"ENST00000590127",11,1838,"ENSG00000078043","PIAS2","GO:0003677(DNA binding);GO:0003713(transcription coactivator activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0008134(transcription factor binding);GO:0008270(zinc ion binding);GO:0016605(PML body);GO:0016607(nuclear speck);GO:0016740(transferase activity);GO:0016925(protein sumoylation);GO:0019789(SUMO transferase activity);GO:0030521(androgen receptor signaling pathway);GO:0031625(ubiquitin protein ligase binding);GO:0045893(positive regulation of transcription, DNA-templated);GO:0046872(metal ion binding);GO:0050681(androgen receptor binding);GO:0060766(negative regulation of androgen receptor signaling pathway);GO:0061665(SUMO ligase activity)","04120(Ubiquitin mediated proteolysis);04630(Jak-STAT signaling pathway)","NA","NA","protein inhibitor of activated STAT 2 [Source:HGNC Symbol;Acc:HGNC:17311]",{"v":0.194543,"d":"0.19"},{"v":0.03592,"d":"0.04"},{"v":0.206155,"d":"0.21"},{"v":2.844257,"d":"2.84"},{"v":1.446722,"d":"1.45"},{"v":0.217255,"d":"0.22"},{"v":0.0968490100558223,"d":"0.10"},{"v":-3.3681188874083,"d":"-3.37"},{"v":0.00854944817166792,"d":"0.01"},{"v":0.359206750816378,"d":"0.36"},"down","yes"]
[35431,0,"chr11","+",94496600,94499562,"ENST00000302755",2,1844,"ENSG00000168876","ANKRD49","GO:0005515(protein binding);GO:0005634(nucleus);GO:0007283(spermatogenesis);GO:0030154(cell differentiation);GO:0045893(positive regulation of transcription, DNA-templated)","NA","K21439","NA","ankyrin repeat domain 49 [Source:HGNC Symbol;Acc:HGNC:25970]",{"v":0.167201,"d":"0.17"},{"v":4.751931,"d":"4.75"},{"v":2.918254,"d":"2.92"},{"v":0.089007,"d":"0.09"},{"v":0.429633,"d":"0.43"},{"v":0.129669,"d":"0.13"},{"v":12.0889668352591,"d":"12.09"},{"v":3.5956190470559,"d":"3.60"},{"v":0.00855254168610423,"d":"0.01"},{"v":0.359206750816378,"d":"0.36"},"up","yes"]
[161360,0,"chr5","-",100806933,100903282,"ENST00000231461",5,6321,"ENSG00000113532","ST8SIA4","GO:0000139(Golgi membrane);GO:0001574(ganglioside biosynthetic process);GO:0003828(alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity);GO:0005794(Golgi apparatus);GO:0006464(cellular protein modification process);GO:0006486(protein glycosylation);GO:0006491(N-glycan processing);GO:0007399(nervous system development);GO:0008373(sialyltransferase activity);GO:0009311(oligosaccharide metabolic process);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016740(transferase activity);GO:0016757(transferase activity, transferring glycosyl groups);GO:0033691(sialic acid binding);GO:0097503(sialylation)","NA","NA","NA","ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4 [Source:HGNC Symbol;Acc:HGNC:10871]",{"v":5.284411,"d":"5.28"},{"v":6.147059,"d":"6.15"},{"v":5.17293,"d":"5.17"},{"v":1.217709,"d":"1.22"},{"v":1.495159,"d":"1.50"},{"v":1.561919,"d":"1.56"},{"v":3.88426370717418,"d":"3.88"},{"v":1.95764115032394,"d":"1.96"},{"v":0.00857541504237636,"d":"0.01"},{"v":0.359751534052579,"d":"0.36"},"up","yes"]
[121801,0,"chr2","-",216257865,216372483,"ENST00000273067",4,4903,"ENSG00000144583","MARCH4","GO:0000139(Golgi membrane);GO:0004842(ubiquitin-protein transferase activity);GO:0005794(Golgi apparatus);GO:0005795(Golgi stack);GO:0005802(trans-Golgi network);GO:0008270(zinc ion binding);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016567(protein ubiquitination);GO:0016740(transferase activity);GO:0046872(metal ion binding)","NA","K10659","EC:2.3.2.27","membrane associated ring-CH-type finger 4 [Source:HGNC Symbol;Acc:HGNC:29269]",{"v":0.308617,"d":"0.31"},{"v":0.331625,"d":"0.33"},{"v":0.2552,"d":"0.26"},{"v":1.739816,"d":"1.74"},{"v":1.693493,"d":"1.69"},{"v":1.853375,"d":"1.85"},{"v":0.169376872156535,"d":"0.17"},{"v":-2.56169120193512,"d":"-2.56"},{"v":0.00866717541592173,"d":"0.01"},{"v":0.363181641130838,"d":"0.36"},"down","yes"]
[124761,0,"chr20","+",3888934,3918789,"ENST00000495692",6,967,"ENSG00000125779","PANK2","GO:0000166(nucleotide binding);GO:0004594(pantothenate kinase activity);GO:0005524(ATP binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005739(mitochondrion);GO:0005758(mitochondrial intermembrane space);GO:0005829(cytosol);GO:0007286(spermatid development);GO:0009060(aerobic respiration);GO:0009108(coenzyme biosynthetic process);GO:0015937(coenzyme A biosynthetic process);GO:0015939(pantothenate metabolic process);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0016740(transferase activity);GO:0019217(regulation of fatty acid metabolic process);GO:0051881(regulation of mitochondrial membrane potential);GO:0070584(mitochondrion morphogenesis);GO:0090207(regulation of triglyceride metabolic process);GO:1904251(regulation of bile acid metabolic process)","00770(Pantothenate and CoA biosynthesis)","K09680","EC:2.7.1.33","pantothenate kinase 2 [Source:HGNC Symbol;Acc:HGNC:15894]",{"v":1.65945,"d":"1.66"},{"v":4.012212,"d":"4.01"},{"v":0.090282,"d":"0.09"},{"v":0.011951,"d":"0.01"},{"v":0.168781,"d":"0.17"},{"v":0.152759,"d":"0.15"},{"v":17.2776596669775,"d":"17.28"},{"v":4.11083590639868,"d":"4.11"},{"v":0.00868254904159023,"d":"0.01"},{"v":0.3632507757812,"d":"0.36"},"up","yes"]
[187801,0,"chr8","-",27596917,27615031,"ENST00000316403",9,3080,"ENSG00000120885","CLU","GO:0000902(cell morphogenesis);GO:0001540(amyloid-beta binding);GO:0001774(microglial cell activation);GO:0001836(release of cytochrome c from mitochondria);GO:0002376(immune system process);GO:0002576(platelet degranulation);GO:0005102(signaling receptor binding);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0005615(extracellular space);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005739(mitochondrion);GO:0005743(mitochondrial inner membrane);GO:0005783(endoplasmic reticulum);GO:0005794(Golgi apparatus);GO:0005829(cytosol);GO:0005856(cytoskeleton);GO:0006629(lipid metabolic process);GO:0006915(apoptotic process);GO:0006956(complement activation);GO:0006958(complement activation, classical pathway);GO:0009615(response to virus);GO:0009986(cell surface);GO:0010628(positive regulation of gene expression);GO:0016020(membrane);GO:0017038(protein import);GO:0019730(antimicrobial humoral response);GO:0030449(regulation of complement activation);GO:0031093(platelet alpha granule lumen);GO:0031410(cytoplasmic vesicle);GO:0031625(ubiquitin protein ligase binding);GO:0031966(mitochondrial membrane);GO:0032286(central nervous system myelin maintenance);GO:0032436(positive regulation of proteasomal ubiquitin-dependent protein catabolic process);GO:0032463(negative regulation of protein homooligomerization);GO:0032464(positive regulation of protein homooligomerization);GO:0032760(positive regulation of tumor necrosis factor production);GO:0032991(protein-containing complex);GO:0034366(spherical high-density lipoprotein particle);GO:0042127(regulation of cell population proliferation);GO:0042583(chromaffin granule);GO:0043065(positive regulation of apoptotic process);GO:0043231(intracellular membrane-bounded organelle);GO:0043691(reverse cholesterol transport);GO:0044877(protein-containing complex binding);GO:0045087(innate immune response);GO:0045202(synapse);GO:0045429(positive regulation of nitric oxide biosynthetic process);GO:0048156(tau protein binding);GO:0048260(positive regulation of receptor-mediated endocytosis);GO:0048471(perinuclear region of cytoplasm);GO:0050750(low-density lipoprotein particle receptor binding);GO:0050821(protein stabilization);GO:0051087(chaperone binding);GO:0051092(positive regulation of NF-kappaB transcription factor activity);GO:0051131(chaperone-mediated protein complex assembly);GO:0051787(misfolded protein binding);GO:0051788(response to misfolded protein);GO:0060548(negative regulation of cell death);GO:0061077(chaperone-mediated protein folding);GO:0061518(microglial cell proliferation);GO:0061740(protein targeting to lysosome involved in chaperone-mediated autophagy);GO:0061741(chaperone-mediated protein transport involved in chaperone-mediated autophagy);GO:0062023(collagen-containing extracellular matrix);GO:0070062(extracellular exosome);GO:0071944(cell periphery);GO:0072562(blood microparticle);GO:0090201(negative regulation of release of cytochrome c from mitochondria);GO:0097418(neurofibrillary tangle);GO:0097440(apical dendrite);GO:0099020(perinuclear endoplasmic reticulum lumen);GO:1900221(regulation of amyloid-beta clearance);GO:1901214(regulation of neuron death);GO:1901216(positive regulation of neuron death);GO:1902004(positive regulation of amyloid-beta formation);GO:1902230(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage);GO:1902430(negative regulation of amyloid-beta formation);GO:1902847(regulation of neuronal signal transduction);GO:1902949(positive regulation of tau-protein kinase activity);GO:1902998(positive regulation of neurofibrillary tangle assembly);GO:1903573(negative regulation of response to endoplasmic reticulum stress);GO:1905892(negative regulation of cellular response to thapsigargin);GO:1905895(negative regulation of cellular response to tunicamycin);GO:1905907(negative regulation of amyloid fibril formation);GO:1905908(positive regulation of amyloid fibril formation);GO:2000060(positive regulation of ubiquitin-dependent protein catabolic process)","04610(Complement and coagulation cascades)","NA","NA","clusterin [Source:HGNC Symbol;Acc:HGNC:2095]",{"v":12.823965,"d":"12.82"},{"v":25.174805,"d":"25.17"},{"v":26.649944,"d":"26.65"},{"v":8.539035,"d":"8.54"},{"v":2.976484,"d":"2.98"},{"v":4.378431,"d":"4.38"},{"v":4.06750455361946,"d":"4.07"},{"v":2.02414396101287,"d":"2.02"},{"v":0.00868882257511321,"d":"0.01"},{"v":0.3632507757812,"d":"0.36"},"up","yes"]
[46502,0,"chr12","+",93378550,93402301,"ENST00000549992",5,3607,"ENSG00000173598","NUDT4","GO:0000298(endopolyphosphatase activity);GO:0003723(RNA binding);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0008486(diphosphoinositol-polyphosphate diphosphatase activity);GO:0016787(hydrolase activity);GO:0019722(calcium-mediated signaling);GO:0019935(cyclic-nucleotide-mediated signaling);GO:0030515(snoRNA binding);GO:0034431(bis(5'-adenosyl)-hexaphosphatase activity);GO:0034432(bis(5'-adenosyl)-pentaphosphatase activity);GO:0035556(intracellular signal transduction);GO:0043647(inositol phosphate metabolic process);GO:0046872(metal ion binding);GO:0050072(m7G(5')pppN diphosphatase activity);GO:0052840(inositol diphosphate tetrakisphosphate diphosphatase activity);GO:0052842(inositol diphosphate pentakisphosphate diphosphatase activity);GO:0071543(diphosphoinositol polyphosphate metabolic process);GO:1901907(diadenosine pentaphosphate catabolic process);GO:1901909(diadenosine hexaphosphate catabolic process);GO:1901911(adenosine 5'-(hexahydrogen pentaphosphate) catabolic process)","NA","K07766","EC:3.6.1.52","nudix hydrolase 4 [Source:HGNC Symbol;Acc:HGNC:8051]",{"v":21.503181,"d":"21.50"},{"v":0.302803,"d":"0.30"},{"v":0.269315,"d":"0.27"},{"v":0.112763,"d":"0.11"},{"v":1.044945,"d":"1.04"},{"v":0.2305,"d":"0.23"},{"v":15.9020110819128,"d":"15.90"},{"v":3.9911373254555,"d":"3.99"},{"v":0.0087071448688096,"d":"0.01"},{"v":0.363598359866497,"d":"0.36"},"up","yes"]
[124429,0,"chr20","+",1134840,1168378,"ENST00000484891",4,4030,"ENSG00000125818","PSMF1","GO:0000165(MAPK cascade);GO:0000209(protein polyubiquitination);GO:0000502(proteasome complex);GO:0002223(stimulatory C-type lectin receptor signaling pathway);GO:0002479(antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent);GO:0004866(endopeptidase inhibitor activity);GO:0005515(protein binding);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0005783(endoplasmic reticulum);GO:0005829(cytosol);GO:0005839(proteasome core complex);GO:0006511(ubiquitin-dependent protein catabolic process);GO:0006521(regulation of cellular amino acid metabolic process);GO:0010951(negative regulation of endopeptidase activity);GO:0010972(negative regulation of G2/M transition of mitotic cell cycle);GO:0016020(membrane);GO:0016579(protein deubiquitination);GO:0031145(anaphase-promoting complex-dependent catabolic process);GO:0031146(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process);GO:0033209(tumor necrosis factor-mediated signaling pathway);GO:0038061(NIK/NF-kappaB signaling);GO:0038095(Fc-epsilon receptor signaling pathway);GO:0042803(protein homodimerization activity);GO:0043161(proteasome-mediated ubiquitin-dependent protein catabolic process);GO:0043488(regulation of mRNA stability);GO:0043687(post-translational protein modification);GO:0046982(protein heterodimerization activity);GO:0048471(perinuclear region of cytoplasm);GO:0050852(T cell receptor signaling pathway);GO:0055085(transmembrane transport);GO:0060071(Wnt signaling pathway, planar cell polarity pathway);GO:0061418(regulation of transcription from RNA polymerase II promoter in response to hypoxia);GO:0070498(interleukin-1-mediated signaling pathway);GO:0070628(proteasome binding);GO:0090090(negative regulation of canonical Wnt signaling pathway);GO:0090263(positive regulation of canonical Wnt signaling pathway);GO:1901799(negative regulation of proteasomal protein catabolic process);GO:1901990(regulation of mitotic cell cycle phase transition);GO:1902036(regulation of hematopoietic stem cell differentiation)","03050(Proteasome)","K06700","NA","proteasome inhibitor subunit 1 [Source:HGNC Symbol;Acc:HGNC:9571]",{"v":1.738652,"d":"1.74"},{"v":1.472712,"d":"1.47"},{"v":0.441517,"d":"0.44"},{"v":0.074281,"d":"0.07"},{"v":0.129195,"d":"0.13"},{"v":0.252294,"d":"0.25"},{"v":8.01474647300173,"d":"8.01"},{"v":3.00265688495524,"d":"3.00"},{"v":0.0087183248662072,"d":"0.01"},{"v":0.363647235808619,"d":"0.36"},"up","yes"]
[2727,0,"chr1","+",23743155,23762059,"ENST00000418390",11,5154,"ENSG00000011007","ELOA","GO:0003746(translation elongation factor activity);GO:0005515(protein binding);GO:0005615(extracellular space);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0006357(regulation of transcription by RNA polymerase II);GO:0006366(transcription by RNA polymerase II);GO:0006368(transcription elongation from RNA polymerase II promoter);GO:0006414(translational elongation);GO:0070449(elongin complex)","NA","K15076","NA","elongin A [Source:HGNC Symbol;Acc:HGNC:11620]",{"v":0.621535,"d":"0.62"},{"v":0.643237,"d":"0.64"},{"v":0.127597,"d":"0.13"},{"v":3.316594,"d":"3.32"},{"v":2.743238,"d":"2.74"},{"v":2.322376,"d":"2.32"},{"v":0.166110051194148,"d":"0.17"},{"v":-2.589788722555,"d":"-2.59"},{"v":0.00880444096558365,"d":"0.01"},{"v":0.36681805077942,"d":"0.37"},"down","yes"]
[162887,0,"chr5","-",135570679,135579064,"ENST00000512158",4,1760,"ENSG00000145824","CXCL14","GO:0005125(cytokine activity);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0005615(extracellular space);GO:0005794(Golgi apparatus);GO:0006935(chemotaxis);GO:0006955(immune response);GO:0007165(signal transduction);GO:0007267(cell-cell signaling);GO:0008009(chemokine activity);GO:0010469(regulation of signaling receptor activity);GO:0045662(negative regulation of myoblast differentiation);GO:0048839(inner ear development);GO:0060326(cell chemotaxis);GO:2000503(positive regulation of natural killer cell chemotaxis)","04060(Cytokine-cytokine receptor interaction);04062(Chemokine signaling pathway)","K10033","NA","C-X-C motif chemokine ligand 14 [Source:HGNC Symbol;Acc:HGNC:10640]",{"v":14.832224,"d":"14.83"},{"v":0.004057,"d":"0.00"},{"v":6.17706,"d":"6.18"},0,{"v":0.353439,"d":"0.35"},{"v":0.249486,"d":"0.25"},{"v":34.8523298917776,"d":"34.85"},{"v":5.1231831989282,"d":"5.12"},{"v":0.00887776001276769,"d":"0.01"},{"v":0.36944905070315,"d":"0.37"},"up","yes"]
[91426,0,"chr17","+",80415452,80438086,"ENST00000517795",7,2548,"ENSG00000173818","ENDOV","GO:0000287(magnesium ion binding);GO:0003677(DNA binding);GO:0003723(RNA binding);GO:0003727(single-stranded RNA binding);GO:0004518(nuclease activity);GO:0004519(endonuclease activity);GO:0005634(nucleus);GO:0005730(nucleolus);GO:0005737(cytoplasm);GO:0006281(DNA repair);GO:0016787(hydrolase activity);GO:0016888(endodeoxyribonuclease activity, producing 5'-phosphomonoesters);GO:0016891(endoribonuclease activity, producing 5'-phosphomonoesters);GO:0046872(metal ion binding);GO:0090305(nucleic acid phosphodiester bond hydrolysis);GO:0090502(RNA phosphodiester bond hydrolysis, endonucleolytic)","NA","K21813","EC:3.1.26.-","endonuclease V [Source:HGNC Symbol;Acc:HGNC:26640]",0,{"v":1.755643,"d":"1.76"},{"v":1.150341,"d":"1.15"},0,0,{"v":0.047236,"d":"0.05"},{"v":61.5205351850284,"d":"61.52"},{"v":5.94299614866545,"d":"5.94"},{"v":0.00889734600639854,"d":"0.01"},{"v":0.36984048102112,"d":"0.37"},"up","yes"]
[161906,0,"chr5","+",119071389,119249127,"ENST00000539542",44,11236,"ENSG00000172869","DMXL1","GO:0005515(protein binding);GO:0007035(vacuolar acidification);GO:0043291(RAVE complex)","NA","NA","NA","Dmx like 1 [Source:HGNC Symbol;Acc:HGNC:2937]",{"v":0.20299,"d":"0.20"},{"v":0.226289,"d":"0.23"},{"v":0.420743,"d":"0.42"},{"v":2.373096,"d":"2.37"},{"v":2.041416,"d":"2.04"},{"v":0.432354,"d":"0.43"},{"v":0.175375593218381,"d":"0.18"},{"v":-2.5114801110321,"d":"-2.51"},{"v":0.00891650175242861,"d":"0.01"},{"v":0.370213152760836,"d":"0.37"},"down","yes"]
[73761,0,"chr16","-",30357107,30368007,"ENST00000478158",7,4614,"ENSG00000169221","TBC1D10B","GO:0005096(GTPase activator activity);GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0006886(intracellular protein transport);GO:0017137(Rab GTPase binding);GO:0042147(retrograde transport, endosome to Golgi);GO:0043087(regulation of GTPase activity);GO:0090630(activation of GTPase activity)","NA","K19944","NA","TBC1 domain family member 10B [Source:HGNC Symbol;Acc:HGNC:24510]",{"v":0.271738,"d":"0.27"},{"v":5.569571,"d":"5.57"},{"v":0.245572,"d":"0.25"},{"v":0.18243,"d":"0.18"},{"v":0.145231,"d":"0.15"},{"v":0.203044,"d":"0.20"},{"v":11.4694246332708,"d":"11.47"},{"v":3.51972111487693,"d":"3.52"},{"v":0.00895938041414319,"d":"0.01"},{"v":0.371568824709843,"d":"0.37"},"up","yes"]
[194595,0,"chr9","-",13105704,13279590,"ENST00000319217",47,7722,"ENSG00000107186","MPDZ","GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0005886(plasma membrane);GO:0005923(bicellular tight junction);GO:0007155(cell adhesion);GO:0008022(protein C-terminus binding);GO:0014069(postsynaptic density);GO:0016020(membrane);GO:0016032(viral process);GO:0016324(apical plasma membrane);GO:0016327(apicolateral plasma membrane);GO:0030054(cell junction);GO:0030425(dendrite);GO:0031410(cytoplasmic vesicle);GO:0042995(cell projection);GO:0043005(neuron projection);GO:0043220(Schmidt-Lanterman incisure);GO:0045202(synapse);GO:0045211(postsynaptic membrane)","04530(Tight junction)","K06095","NA","multiple PDZ domain crumbs cell polarity complex component [Source:HGNC Symbol;Acc:HGNC:7208]",{"v":0.036827,"d":"0.04"},{"v":0.046226,"d":"0.05"},{"v":0.043267,"d":"0.04"},{"v":0.610191,"d":"0.61"},{"v":0.195475,"d":"0.20"},{"v":0.139442,"d":"0.14"},{"v":0.133656682622515,"d":"0.13"},{"v":-2.9033961230352,"d":"-2.90"},{"v":0.00899845402029584,"d":"0.01"},{"v":0.372445283062872,"d":"0.37"},"down","yes"]
[138186,0,"chr3","-",36826820,36945057,"ENST00000429976",23,10481,"ENSG00000168016","TRANK1","GO:0005515(protein binding);GO:0005524(ATP binding)","NA","NA","NA","tetratricopeptide repeat and ankyrin repeat containing 1 [Source:HGNC Symbol;Acc:HGNC:29011]",{"v":0.002469,"d":"0.00"},0,{"v":0.024283,"d":"0.02"},{"v":0.12419,"d":"0.12"},0,{"v":1.334774,"d":"1.33"},{"v":0.0183362989079922,"d":"0.02"},{"v":-5.76915372237556,"d":"-5.77"},{"v":0.00900101730055605,"d":"0.01"},{"v":0.372445283062872,"d":"0.37"},"down","yes"]
[34382,0,"chr11","+",75567782,75572782,"ENST00000525876",3,2283,"ENSG00000149257","SERPINH1","GO:0003433(chondrocyte development involved in endochondral bone morphogenesis);GO:0003723(RNA binding);GO:0004867(serine-type endopeptidase inhibitor activity);GO:0005518(collagen binding);GO:0005581(collagen trimer);GO:0005615(extracellular space);GO:0005737(cytoplasm);GO:0005783(endoplasmic reticulum);GO:0005788(endoplasmic reticulum lumen);GO:0005793(endoplasmic reticulum-Golgi intermediate compartment);GO:0006986(response to unfolded protein);GO:0010951(negative regulation of endopeptidase activity);GO:0030199(collagen fibril organization);GO:0032964(collagen biosynthetic process);GO:0045121(membrane raft);GO:0051082(unfolded protein binding);GO:0051604(protein maturation);GO:0062023(collagen-containing extracellular matrix)","NA","NA","NA","serpin family H member 1 [Source:HGNC Symbol;Acc:HGNC:1546]",{"v":26.545855,"d":"26.55"},{"v":1.607849,"d":"1.61"},{"v":35.939854,"d":"35.94"},{"v":2.941149,"d":"2.94"},{"v":1.903134,"d":"1.90"},{"v":5.550694,"d":"5.55"},{"v":6.16582008791361,"d":"6.17"},{"v":2.62429279374908,"d":"2.62"},{"v":0.00901137760765592,"d":"0.01"},{"v":0.372449770746462,"d":"0.37"},"up","yes"]
[15562,0,"chr1","+",203795714,203854999,"ENST00000550078",17,12481,"ENSG00000257315","ZBED6","GO:0000981(DNA-binding transcription factor activity, RNA polymerase II-specific);GO:0003677(DNA binding);GO:0005634(nucleus);GO:0005730(nucleolus);GO:0006357(regulation of transcription by RNA polymerase II);GO:0045892(negative regulation of transcription, DNA-templated);GO:0046872(metal ion binding);GO:0046983(protein dimerization activity)","NA","NA","NA","zinc finger BED-type containing 6 [Source:HGNC Symbol;Acc:HGNC:33273]",{"v":0.71575,"d":"0.72"},{"v":2.608027,"d":"2.61"},{"v":3.201901,"d":"3.20"},{"v":0.423837,"d":"0.42"},{"v":0.475913,"d":"0.48"},{"v":0.439807,"d":"0.44"},{"v":4.87151946501717,"d":"4.87"},{"v":2.28437183036493,"d":"2.28"},{"v":0.00909269358698949,"d":"0.01"},{"v":0.375383588653782,"d":"0.38"},"up","yes"]
[32299,0,"chr11","+",65422804,65424404,"ENST00000612303",3,1053,"ENSG00000245532","NEAT1","NA","NA","NA","NA","nuclear paraspeckle assembly transcript 1 [Source:HGNC Symbol;Acc:HGNC:30815]",{"v":1.861436,"d":"1.86"},{"v":1.833912,"d":"1.83"},{"v":1.992321,"d":"1.99"},{"v":9.712152,"d":"9.71"},{"v":2.715785,"d":"2.72"},{"v":26.027351,"d":"26.03"},{"v":0.14790343008223,"d":"0.15"},{"v":-2.7572725839971,"d":"-2.76"},{"v":0.00911984835874944,"d":"0.01"},{"v":0.376077288165002,"d":"0.38"},"down","yes"]
[89537,0,"chr17","-",68931762,68955392,"ENST00000585850",6,1502,"ENSG00000141338","ABCA8","GO:0000166(nucleotide binding);GO:0005319(lipid transporter activity);GO:0005524(ATP binding);GO:0005886(plasma membrane);GO:0006869(lipid transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016887(ATPase activity);GO:0042626(ATPase activity, coupled to transmembrane movement of substances);GO:0043231(intracellular membrane-bounded organelle);GO:0055085(transmembrane transport)","02010(ABC transporters)","K05650","NA","ATP binding cassette subfamily A member 8 [Source:HGNC Symbol;Acc:HGNC:38]",{"v":0.058637,"d":"0.06"},0,0,{"v":0.389631,"d":"0.39"},{"v":0.641712,"d":"0.64"},{"v":0.620696,"d":"0.62"},{"v":0.0354937141314461,"d":"0.04"},{"v":-4.81629264105482,"d":"-4.82"},{"v":0.00918548799888204,"d":"0.01"},{"v":0.378354624715856,"d":"0.38"},"down","yes"]
[182608,0,"chr7","-",104187543,104208009,"ENST00000485726",7,1214,"ENSG00000164815","ORC5","GO:0000082(G1/S transition of mitotic cell cycle);GO:0000166(nucleotide binding);GO:0000784(nuclear chromosome, telomeric region);GO:0000808(origin recognition complex);GO:0003674(molecular_function);GO:0003688(DNA replication origin binding);GO:0005515(protein binding);GO:0005524(ATP binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005664(nuclear origin of replication recognition complex);GO:0005829(cytosol);GO:0006260(DNA replication);GO:0006270(DNA replication initiation)","04110(Cell cycle)","K02607","NA","origin recognition complex subunit 5 [Source:HGNC Symbol;Acc:HGNC:8491]",{"v":0.00552,"d":"0.01"},0,{"v":0.054198,"d":"0.05"},{"v":0.868109,"d":"0.87"},{"v":1.788405,"d":"1.79"},{"v":0.00803,"d":"0.01"},{"v":0.0224120900236588,"d":"0.02"},{"v":-5.47957899714372,"d":"-5.48"},{"v":0.0092013170477658,"d":"0.01"},{"v":0.3785774046946,"d":"0.38"},"down","yes"]
[191423,0,"chr8","-",100257060,100303259,"ENST00000519449",11,4330,"ENSG00000034677","RNF19A","GO:0000151(ubiquitin ligase complex);GO:0000209(protein polyubiquitination);GO:0000226(microtubule cytoskeleton organization);GO:0004842(ubiquitin-protein transferase activity);GO:0005737(cytoplasm);GO:0005813(centrosome);GO:0005815(microtubule organizing center);GO:0005829(cytosol);GO:0005856(cytoskeleton);GO:0006511(ubiquitin-dependent protein catabolic process);GO:0008134(transcription factor binding);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016567(protein ubiquitination);GO:0016740(transferase activity);GO:0031624(ubiquitin conjugating enzyme binding);GO:0032436(positive regulation of proteasomal ubiquitin-dependent protein catabolic process);GO:0046872(metal ion binding);GO:0061630(ubiquitin protein ligase activity);GO:0098686(hippocampal mossy fiber to CA3 synapse);GO:0098794(postsynapse);GO:0098978(glutamatergic synapse);GO:0099576(regulation of protein catabolic process at postsynapse, modulating synaptic transmission)","NA","K11972","EC:2.3.2.31","ring finger protein 19A, RBR E3 ubiquitin protein ligase [Source:HGNC Symbol;Acc:HGNC:13432]",{"v":0.565578,"d":"0.57"},{"v":9.43445,"d":"9.43"},{"v":5.460529,"d":"5.46"},{"v":0.595834,"d":"0.60"},{"v":0.005254,"d":"0.01"},0,{"v":25.7209543361371,"d":"25.72"},{"v":4.68487226750928,"d":"4.68"},{"v":0.00923922700701542,"d":"0.01"},{"v":0.379707146114106,"d":"0.38"},"up","yes"]
[93701,0,"chr18","-",25062593,25352155,"ENST00000538137",8,4253,"ENSG00000198795","ZNF521","GO:0000981(DNA-binding transcription factor activity, RNA polymerase II-specific);GO:0003676(nucleic acid binding);GO:0003677(DNA binding);GO:0005634(nucleus);GO:0006357(regulation of transcription by RNA polymerase II);GO:0007275(multicellular organism development);GO:0019904(protein domain specific binding);GO:0030154(cell differentiation);GO:0046872(metal ion binding);GO:0048663(neuron fate commitment)","NA","NA","NA","zinc finger protein 521 [Source:HGNC Symbol;Acc:HGNC:24605]",{"v":0.121538,"d":"0.12"},{"v":4.088484,"d":"4.09"},{"v":0.222975,"d":"0.22"},{"v":0.167919,"d":"0.17"},{"v":0.081067,"d":"0.08"},{"v":0.087125,"d":"0.09"},{"v":13.1890863434996,"d":"13.19"},{"v":3.72127272214878,"d":"3.72"},{"v":0.00926249457886081,"d":"0.01"},{"v":0.379829229238543,"d":"0.38"},"up","yes"]
[160005,0,"chr5","-",74627431,74640582,"ENST00000651128",4,7285,"ENSG00000171617","ENC1","GO:0000790(nuclear chromatin);GO:0003779(actin binding);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005730(nucleolus);GO:0005737(cytoplasm);GO:0005856(cytoskeleton);GO:0007275(multicellular organism development);GO:0007399(nervous system development);GO:0010499(proteasomal ubiquitin-independent protein catabolic process);GO:0010976(positive regulation of neuron projection development);GO:0016363(nuclear matrix);GO:0016567(protein ubiquitination);GO:0017148(negative regulation of translation);GO:0031463(Cul3-RING ubiquitin ligase complex);GO:0043025(neuronal cell body)","NA","K10462","NA","ectodermal-neural cortex 1 [Source:HGNC Symbol;Acc:HGNC:3345]",{"v":0.312972,"d":"0.31"},{"v":0.11704,"d":"0.12"},{"v":0.218954,"d":"0.22"},{"v":2.061756,"d":"2.06"},{"v":0.222967,"d":"0.22"},{"v":2.65609,"d":"2.66"},{"v":0.131348019040591,"d":"0.13"},{"v":-2.9285336526333,"d":"-2.93"},{"v":0.00926310754487612,"d":"0.01"},{"v":0.379829229238543,"d":"0.38"},"down","yes"]
[93302,0,"chr18","+",13726661,13764558,"ENST00000383314",12,6250,"ENSG00000101654","RNMT","GO:0001650(fibrillar center);GO:0003723(RNA binding);GO:0004482(mRNA (guanine-N7-)-methyltransferase activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005845(mRNA cap binding complex);GO:0006366(transcription by RNA polymerase II);GO:0006370(7-methylguanosine mRNA capping);GO:0006397(mRNA processing);GO:0008168(methyltransferase activity);GO:0016740(transferase activity);GO:0031533(mRNA cap methyltransferase complex);GO:0032259(methylation);GO:0043235(receptor complex);GO:0106005(RNA 5'-cap (guanine-N7)-methylation);GO:1990830(cellular response to leukemia inhibitory factor)","03015(mRNA surveillance pathway)","K00565","EC:2.1.1.56","RNA guanine-7 methyltransferase [Source:HGNC Symbol;Acc:HGNC:10075]",{"v":0.339172,"d":"0.34"},{"v":0.104158,"d":"0.10"},{"v":0.111238,"d":"0.11"},{"v":0.512783,"d":"0.51"},{"v":4.804167,"d":"4.80"},{"v":0.229732,"d":"0.23"},{"v":0.0999819351460928,"d":"0.10"},{"v":-3.32218873918204,"d":"-3.32"},{"v":0.00943357933372734,"d":"0.01"},{"v":0.386383243736544,"d":"0.39"},"down","yes"]
[85263,0,"chr17","-",40627743,40647846,"ENST00000646401",10,3644,"ENSG00000073584","SMARCE1","GO:0000228(nuclear chromosome);GO:0000790(nuclear chromatin);GO:0000978(RNA polymerase II proximal promoter sequence-specific DNA binding);GO:0000980(RNA polymerase II distal enhancer sequence-specific DNA binding);GO:0000981(DNA-binding transcription factor activity, RNA polymerase II-specific);GO:0003677(DNA binding);GO:0003682(chromatin binding);GO:0003713(transcription coactivator activity);GO:0003723(RNA binding);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0006325(chromatin organization);GO:0006337(nucleosome disassembly);GO:0006338(chromatin remodeling);GO:0006357(regulation of transcription by RNA polymerase II);GO:0007399(nervous system development);GO:0008080(N-acetyltransferase activity);GO:0016514(SWI/SNF complex);GO:0016922(nuclear receptor binding);GO:0022008(neurogenesis);GO:0031492(nucleosomal DNA binding);GO:0032991(protein-containing complex);GO:0043044(ATP-dependent chromatin remodeling);GO:0045892(negative regulation of transcription, DNA-templated);GO:0047485(protein N-terminus binding);GO:0071564(npBAF complex);GO:0071565(nBAF complex);GO:1903508(positive regulation of nucleic acid-templated transcription)","04714(Thermogenesis);05225(Hepatocellular carcinoma)","K11651","NA","SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1 [Source:HGNC Symbol;Acc:HGNC:11109]",{"v":1.008581,"d":"1.01"},{"v":1.109933,"d":"1.11"},{"v":0.090216,"d":"0.09"},{"v":0.032432,"d":"0.03"},{"v":0.046033,"d":"0.05"},{"v":0.140975,"d":"0.14"},{"v":10.0653025884069,"d":"10.07"},{"v":3.33131863885373,"d":"3.33"},{"v":0.00945307134055727,"d":"0.01"},{"v":0.386745587615367,"d":"0.39"},"up","yes"]
[126423,0,"chr20","-",35648925,35664900,"ENST00000374114",3,6646,"ENSG00000244462","RBM12","GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm)","NA","NA","NA","RNA binding motif protein 12 [Source:HGNC Symbol;Acc:HGNC:9898]",{"v":0.933909,"d":"0.93"},{"v":1.103492,"d":"1.10"},{"v":1.363056,"d":"1.36"},{"v":4.238953,"d":"4.24"},{"v":4.497424,"d":"4.50"},{"v":4.529277,"d":"4.53"},{"v":0.256335420779104,"d":"0.26"},{"v":-1.96389524890881,"d":"-1.96"},{"v":0.00951041395148898,"d":"0.01"},{"v":0.388653924474235,"d":"0.39"},"down","yes"]
[163076,0,"chr5","+",138179112,138187723,"ENST00000394894",19,3095,"ENSG00000112984","KIF20A","GO:0000166(nucleotide binding);GO:0000281(mitotic cytokinesis);GO:0001578(microtubule bundle formation);GO:0003774(motor activity);GO:0003777(microtubule motor activity);GO:0005215(transporter activity);GO:0005515(protein binding);GO:0005524(ATP binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0005794(Golgi apparatus);GO:0005819(spindle);GO:0005856(cytoskeleton);GO:0005871(kinesin complex);GO:0005874(microtubule);GO:0007018(microtubule-based movement);GO:0008017(microtubule binding);GO:0015031(protein transport);GO:0016192(vesicle-mediated transport);GO:0016887(ATPase activity);GO:0019901(protein kinase binding);GO:0030496(midbody);GO:0032154(cleavage furrow);GO:0032465(regulation of cytokinesis);GO:0045171(intercellular bridge);GO:0061952(midbody abscission)","NA","K10402","NA","kinesin family member 20A [Source:HGNC Symbol;Acc:HGNC:9787]",{"v":0.425614,"d":"0.43"},{"v":0.617218,"d":"0.62"},{"v":0.25405,"d":"0.25"},{"v":3.020701,"d":"3.02"},{"v":2.758926,"d":"2.76"},{"v":2.055019,"d":"2.06"},{"v":0.165531665374543,"d":"0.17"},{"v":-2.59482087115377,"d":"-2.59"},{"v":0.00959116509980927,"d":"0.01"},{"v":0.391513514692214,"d":"0.39"},"down","yes"]
[55011,0,"chr14","+",24094159,24100562,"ENST00000396973",7,1830,"ENSG00000100889","PCK2","GO:0000166(nucleotide binding);GO:0004611(phosphoenolpyruvate carboxykinase activity);GO:0004613(phosphoenolpyruvate carboxykinase (GTP) activity);GO:0005515(protein binding);GO:0005525(GTP binding);GO:0005739(mitochondrion);GO:0005759(mitochondrial matrix);GO:0005829(cytosol);GO:0006090(pyruvate metabolic process);GO:0006094(gluconeogenesis);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0016829(lyase activity);GO:0016831(carboxy-lyase activity);GO:0017076(purine nucleotide binding);GO:0019543(propionate catabolic process);GO:0030145(manganese ion binding);GO:0032869(cellular response to insulin stimulus);GO:0033993(response to lipid);GO:0042594(response to starvation);GO:0046327(glycerol biosynthetic process from pyruvate);GO:0046872(metal ion binding);GO:0070365(hepatocyte differentiation);GO:0071333(cellular response to glucose stimulus);GO:0071549(cellular response to dexamethasone stimulus)","00010(Glycolysis / Gluconeogenesis);00020(Citrate cycle (TCA cycle));00620(Pyruvate metabolism);03320(PPAR signaling pathway);04068(FoxO signaling pathway);04151(PI3K-Akt signaling pathway);04152(AMPK signaling pathway);04910(Insulin signaling pathway);04920(Adipocytokine signaling pathway);04922(Glucagon signaling pathway);04931(Insulin resistance);04964(Proximal tubule bicarbonate reclamation)","NA","NA","phosphoenolpyruvate carboxykinase 2, mitochondrial [Source:HGNC Symbol;Acc:HGNC:8725]",{"v":1.100881,"d":"1.10"},{"v":2.746077,"d":"2.75"},{"v":1.927115,"d":"1.93"},{"v":13.741406,"d":"13.74"},{"v":13.159119,"d":"13.16"},{"v":3.765674,"d":"3.77"},{"v":0.188287860520308,"d":"0.19"},{"v":-2.40898810678713,"d":"-2.41"},{"v":0.00961173136008618,"d":"0.01"},{"v":0.391656130784056,"d":"0.39"},"down","yes"]
[201493,0,"chrX","+",11759634,11775726,"ENST00000380693",12,2267,"ENSG00000005302","MSL3","GO:0000123(histone acetyltransferase complex);GO:0003677(DNA binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0006325(chromatin organization);GO:0006342(chromatin silencing);GO:0006355(regulation of transcription, DNA-templated);GO:0016573(histone acetylation);GO:0016575(histone deacetylation);GO:0035064(methylated histone binding);GO:0035267(NuA4 histone acetyltransferase complex);GO:0043967(histone H4 acetylation);GO:0043968(histone H2A acetylation);GO:0043984(histone H4-K16 acetylation);GO:0072487(MSL complex)","NA","K18403","NA","MSL complex subunit 3 [Source:HGNC Symbol;Acc:HGNC:7370]",0,{"v":0.013219,"d":"0.01"},0,{"v":0.704448,"d":"0.70"},{"v":0.46372,"d":"0.46"},0,{"v":0.0113160093411222,"d":"0.01"},{"v":-6.46549091701372,"d":"-6.47"},{"v":0.00961621989153256,"d":"0.01"},{"v":0.391656130784056,"d":"0.39"},"down","yes"]
[137721,0,"chr3","-",25597905,25664372,"ENST00000264331",36,5358,"ENSG00000077097","TOP2B","GO:0000166(nucleotide binding);GO:0000712(resolution of meiotic recombination intermediates);GO:0000792(heterochromatin);GO:0000819(sister chromatid segregation);GO:0001764(neuron migration);GO:0003677(DNA binding);GO:0003682(chromatin binding);GO:0003916(DNA topoisomerase activity);GO:0003918(DNA topoisomerase type II (ATP-hydrolyzing) activity);GO:0005080(protein kinase C binding);GO:0005524(ATP binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0006259(DNA metabolic process);GO:0006265(DNA topological change);GO:0007409(axonogenesis);GO:0008022(protein C-terminus binding);GO:0016853(isomerase activity);GO:0019035(viral integration complex);GO:0019899(enzyme binding);GO:0030900(forebrain development);GO:0042826(histone deacetylase binding);GO:0044774(mitotic DNA integrity checkpoint);GO:0045870(positive regulation of single stranded viral RNA replication via double stranded DNA intermediate);GO:0046872(metal ion binding);GO:0046982(protein heterodimerization activity);GO:0061505(DNA topoisomerase II activity);GO:1990904(ribonucleoprotein complex)","01524(Platinum drug resistance)","K03164","EC:5.6.2.2","DNA topoisomerase II beta [Source:HGNC Symbol;Acc:HGNC:11990]",{"v":0.096104,"d":"0.10"},{"v":0.266782,"d":"0.27"},{"v":0.259725,"d":"0.26"},{"v":11.598414,"d":"11.60"},{"v":0.003706,"d":"0.00"},{"v":0.386469,"d":"0.39"},{"v":0.0519336345586624,"d":"0.05"},{"v":-4.26718699426873,"d":"-4.27"},{"v":0.00965486275352265,"d":"0.01"},{"v":0.392789657150591,"d":"0.39"},"down","yes"]
[77041,0,"chr16","+",70145795,70158315,"ENST00000564563",6,2381,"ENSG00000090857","PDPR","GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0005739(mitochondrion);GO:0005759(mitochondrial matrix);GO:0010510(regulation of acetyl-CoA biosynthetic process from pyruvate);GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process)","NA","K17509","NA","pyruvate dehydrogenase phosphatase regulatory subunit [Source:HGNC Symbol;Acc:HGNC:30264]",0,{"v":0.537848,"d":"0.54"},{"v":0.893228,"d":"0.89"},{"v":0.005511,"d":"0.01"},0,{"v":0.015337,"d":"0.02"},{"v":68.6433231005372,"d":"68.64"},{"v":6.1010474919063,"d":"6.10"},{"v":0.00975175994382619,"d":"0.01"},{"v":0.396240552038115,"d":"0.40"},"up","yes"]
[154879,0,"chr4","+",133149294,133194700,"ENST00000264360",5,8510,"ENSG00000138650","PCDH10","GO:0005509(calcium ion binding);GO:0005886(plasma membrane);GO:0005887(integral component of plasma membrane);GO:0007155(cell adhesion);GO:0007156(homophilic cell adhesion via plasma membrane adhesion molecules);GO:0016020(membrane);GO:0016021(integral component of membrane)","NA","K16499","NA","protocadherin 10 [Source:HGNC Symbol;Acc:HGNC:13404]",{"v":0.364235,"d":"0.36"},{"v":0.068731,"d":"0.07"},{"v":0.382491,"d":"0.38"},{"v":0.055423,"d":"0.06"},{"v":0.005815,"d":"0.01"},{"v":0.023429,"d":"0.02"},{"v":9.63134397108673,"d":"9.63"},{"v":3.26773712778155,"d":"3.27"},{"v":0.00976149997451453,"d":"0.01"},{"v":0.396240552038115,"d":"0.40"},"up","yes"]
[200437,0,"chr9","+",135500699,135503960,"ENST00000488610",5,928,"ENSG00000122140","MRPS2","GO:0003735(structural constituent of ribosome);GO:0005622(intracellular);GO:0005739(mitochondrion);GO:0005743(mitochondrial inner membrane);GO:0005763(mitochondrial small ribosomal subunit);GO:0005840(ribosome);GO:0006412(translation);GO:0015935(small ribosomal subunit);GO:0032543(mitochondrial translation);GO:0061668(mitochondrial ribosome assembly);GO:0070125(mitochondrial translational elongation);GO:0070126(mitochondrial translational termination)","03010(Ribosome)","K02967","NA","mitochondrial ribosomal protein S2 [Source:HGNC Symbol;Acc:HGNC:14495]",{"v":0.570171,"d":"0.57"},{"v":0.662919,"d":"0.66"},{"v":0.236911,"d":"0.24"},{"v":5.562568,"d":"5.56"},{"v":0.541222,"d":"0.54"},{"v":7.097214,"d":"7.10"},{"v":0.111355242373989,"d":"0.11"},{"v":-3.16675861607082,"d":"-3.17"},{"v":0.00986419231567221,"d":"0.01"},{"v":0.399938446631256,"d":"0.40"},"down","yes"]
[92770,0,"chr18","+",6788494,6898719,"ENST00000262227",17,5369,"ENSG00000088756","ARHGAP28","GO:0005096(GTPase activator activity);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0007165(signal transduction);GO:0030833(regulation of actin filament polymerization);GO:0032956(regulation of actin cytoskeleton organization);GO:0043547(positive regulation of GTPase activity);GO:0051056(regulation of small GTPase mediated signal transduction);GO:0051497(negative regulation of stress fiber assembly);GO:1904425(negative regulation of GTP binding)","NA","K20639","NA","Rho GTPase activating protein 28 [Source:HGNC Symbol;Acc:HGNC:25509]",{"v":0.059505,"d":"0.06"},{"v":0.814783,"d":"0.81"},{"v":0.730828,"d":"0.73"},{"v":0.051345,"d":"0.05"},0,{"v":0.053172,"d":"0.05"},{"v":15.3574633791632,"d":"15.36"},{"v":3.94086803799629,"d":"3.94"},{"v":0.00987461565175439,"d":"0.01"},{"v":0.399938446631256,"d":"0.40"},"up","yes"]
[168791,0,"chr6","+",30888730,30899418,"ENST00000513240",17,2882,"ENSG00000204580","DDR1","GO:0000166(nucleotide binding);GO:0001558(regulation of cell growth);GO:0001952(regulation of cell-matrix adhesion);GO:0004672(protein kinase activity);GO:0004713(protein tyrosine kinase activity);GO:0004714(transmembrane receptor protein tyrosine kinase activity);GO:0005515(protein binding);GO:0005518(collagen binding);GO:0005524(ATP binding);GO:0005576(extracellular region);GO:0005615(extracellular space);GO:0005886(plasma membrane);GO:0005887(integral component of plasma membrane);GO:0006468(protein phosphorylation);GO:0007155(cell adhesion);GO:0007160(cell-matrix adhesion);GO:0007169(transmembrane receptor protein tyrosine kinase signaling pathway);GO:0007565(female pregnancy);GO:0007566(embryo implantation);GO:0007595(lactation);GO:0008284(positive regulation of cell population proliferation);GO:0008285(negative regulation of cell population proliferation);GO:0010715(regulation of extracellular matrix disassembly);GO:0014909(smooth muscle cell migration);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0016740(transferase activity);GO:0018108(peptidyl-tyrosine phosphorylation);GO:0030154(cell differentiation);GO:0030198(extracellular matrix organization);GO:0038062(protein tyrosine kinase collagen receptor activity);GO:0038063(collagen-activated tyrosine kinase receptor signaling pathway);GO:0038083(peptidyl-tyrosine autophosphorylation);GO:0043235(receptor complex);GO:0043583(ear development);GO:0044319(wound healing, spreading of cells);GO:0046777(protein autophosphorylation);GO:0046872(metal ion binding);GO:0060444(branching involved in mammary gland duct morphogenesis);GO:0060749(mammary gland alveolus development);GO:0061302(smooth muscle cell-matrix adhesion);GO:0061564(axon development);GO:0070062(extracellular exosome);GO:1903053(regulation of extracellular matrix organization);GO:1990138(neuron projection extension)","NA","NA","NA","discoidin domain receptor tyrosine kinase 1 [Source:HGNC Symbol;Acc:HGNC:2730]",{"v":0.020053,"d":"0.02"},0,0,{"v":0.706621,"d":"0.71"},{"v":0.904143,"d":"0.90"},0,{"v":0.0124493718508733,"d":"0.01"},{"v":-6.32778323868556,"d":"-6.33"},{"v":0.0099476871980974,"d":"0.01"},{"v":0.402449305018796,"d":"0.40"},"down","yes"]
[11665,0,"chr1","+",153990763,153992150,"ENST00000643794",5,467,"ENSG00000177954","RPS27","GO:0000028(ribosomal small subunit assembly);GO:0000184(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay);GO:0003677(DNA binding);GO:0003723(RNA binding);GO:0003735(structural constituent of ribosome);GO:0005515(protein binding);GO:0005622(intracellular);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0005840(ribosome);GO:0006364(rRNA processing);GO:0006412(translation);GO:0006413(translational initiation);GO:0006614(SRP-dependent cotranslational protein targeting to membrane);GO:0008270(zinc ion binding);GO:0008283(cell population proliferation);GO:0014069(postsynaptic density);GO:0019083(viral transcription);GO:0022627(cytosolic small ribosomal subunit);GO:0046872(metal ion binding);GO:0098793(presynapse);GO:0098978(glutamatergic synapse);GO:0098982(GABA-ergic synapse)","03010(Ribosome)","K02978","NA","ribosomal protein S27 [Source:HGNC Symbol;Acc:HGNC:10416]",{"v":6.738108,"d":"6.74"},{"v":73.369682,"d":"73.37"},{"v":5.476878,"d":"5.48"},{"v":2.790401,"d":"2.79"},{"v":3.988953,"d":"3.99"},{"v":3.247382,"d":"3.25"},{"v":8.53564589712943,"d":"8.54"},{"v":3.09350032692947,"d":"3.09"},{"v":0.0100996386508571,"d":"0.01"},{"v":0.408142238248764,"d":"0.41"},"up","yes"]
[124741,0,"chr20","+",3786772,3806121,"ENST00000344256",16,3071,"ENSG00000101224","CDC25B","GO:0000086(G2/M transition of mitotic cell cycle);GO:0000278(mitotic cell cycle);GO:0000922(spindle pole);GO:0001556(oocyte maturation);GO:0004721(phosphoprotein phosphatase activity);GO:0004725(protein tyrosine phosphatase activity);GO:0005515(protein binding);GO:0005622(intracellular);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0005813(centrosome);GO:0005815(microtubule organizing center);GO:0005829(cytosol);GO:0005856(cytoskeleton);GO:0006468(protein phosphorylation);GO:0006470(protein dephosphorylation);GO:0007049(cell cycle);GO:0007144(female meiosis I);GO:0008284(positive regulation of cell population proliferation);GO:0010971(positive regulation of G2/M transition of mitotic cell cycle);GO:0016787(hydrolase activity);GO:0019901(protein kinase binding);GO:0032467(positive regulation of cytokinesis);GO:0035335(peptidyl-tyrosine dephosphorylation);GO:0045860(positive regulation of protein kinase activity);GO:0045931(positive regulation of mitotic cell cycle);GO:0051301(cell division);GO:0110032(positive regulation of G2/MI transition of meiotic cell cycle);GO:1902751(positive regulation of cell cycle G2/M phase transition)","04010(MAPK signaling pathway);04110(Cell cycle);04914(Progesterone-mediated oocyte maturation);05206(MicroRNAs in cancer)","NA","NA","cell division cycle 25B [Source:HGNC Symbol;Acc:HGNC:1726]",{"v":0.325107,"d":"0.33"},{"v":0.280259,"d":"0.28"},{"v":0.269918,"d":"0.27"},{"v":0.000241,"d":"0.00"},{"v":0.002756,"d":"0.00"},{"v":0.043315,"d":"0.04"},{"v":18.8997236137502,"d":"18.90"},{"v":4.24029323176824,"d":"4.24"},{"v":0.0101600610043368,"d":"0.01"},{"v":0.41012779587506,"d":"0.41"},"up","yes"]
[110265,0,"chr2","+",20667144,20679243,"ENST00000272224",2,9267,"ENSG00000143869","GDF7","GO:0005125(cytokine activity);GO:0005160(transforming growth factor beta receptor binding);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0005615(extracellular space);GO:0007411(axon guidance);GO:0008083(growth factor activity);GO:0010469(regulation of signaling receptor activity);GO:0010628(positive regulation of gene expression);GO:0010862(positive regulation of pathway-restricted SMAD protein phosphorylation);GO:0021509(roof plate formation);GO:0021527(spinal cord association neuron differentiation);GO:0021915(neural tube development);GO:0022612(gland morphogenesis);GO:0030509(BMP signaling pathway);GO:0030855(epithelial cell differentiation);GO:0030901(midbrain development);GO:0032924(activin receptor signaling pathway);GO:0042803(protein homodimerization activity);GO:0042981(regulation of apoptotic process);GO:0043408(regulation of MAPK cascade);GO:0045165(cell fate commitment);GO:0045666(positive regulation of neuron differentiation);GO:0045893(positive regulation of transcription, DNA-templated);GO:0048468(cell development);GO:0048608(reproductive structure development);GO:0048754(branching morphogenesis of an epithelial tube);GO:0048853(forebrain morphogenesis);GO:0060389(pathway-restricted SMAD protein phosphorylation);GO:0060395(SMAD protein signal transduction);GO:0060571(morphogenesis of an epithelial fold);GO:2001051(positive regulation of tendon cell differentiation)","04060(Cytokine-cytokine receptor interaction);04350(TGF-beta signaling pathway);04360(Axon guidance);04390(Hippo signaling pathway)","K20013","NA","growth differentiation factor 7 [Source:HGNC Symbol;Acc:HGNC:4222]",{"v":0.280597,"d":"0.28"},{"v":0.369589,"d":"0.37"},{"v":0.438119,"d":"0.44"},{"v":1.628711,"d":"1.63"},{"v":1.816925,"d":"1.82"},{"v":1.720095,"d":"1.72"},{"v":0.210677830494852,"d":"0.21"},{"v":-2.24688958670223,"d":"-2.25"},{"v":0.0103724759820828,"d":"0.01"},{"v":0.417899918733839,"d":"0.42"},"down","yes"]
[80477,0,"chr17","+",6444455,6451469,"ENST00000572447",6,1908,"ENSG00000129195","PIMREG","GO:0005515(protein binding);GO:0005634(nucleus);GO:0005730(nucleolus);GO:0007049(cell cycle);GO:0051301(cell division)","NA","NA","NA","PICALM interacting mitotic regulator [Source:HGNC Symbol;Acc:HGNC:25483]",{"v":0.216802,"d":"0.22"},{"v":0.188587,"d":"0.19"},{"v":0.205638,"d":"0.21"},{"v":1.583889,"d":"1.58"},{"v":1.133723,"d":"1.13"},{"v":1.091354,"d":"1.09"},{"v":0.160418076716883,"d":"0.16"},{"v":-2.64009137379041,"d":"-2.64"},{"v":0.0103756049187427,"d":"0.01"},{"v":0.417899918733839,"d":"0.42"},"down","yes"]
[72586,0,"chr16","+",22297375,22335101,"ENST00000615879",20,3655,"ENSG00000058600","POLR3E","GO:0001056(RNA polymerase III activity);GO:0002376(immune system process);GO:0003899(DNA-directed 5'-3' RNA polymerase activity);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005666(RNA polymerase III complex);GO:0005829(cytosol);GO:0006351(transcription, DNA-templated);GO:0006383(transcription by RNA polymerase III);GO:0032481(positive regulation of type I interferon production);GO:0045087(innate immune response);GO:0051607(defense response to virus)","03020(RNA polymerase);04623(Cytosolic DNA-sensing pathway)","K14721","NA","RNA polymerase III subunit E [Source:HGNC Symbol;Acc:HGNC:30347]",{"v":0.726794,"d":"0.73"},{"v":0.37084,"d":"0.37"},0,0,0,{"v":0.015662,"d":"0.02"},{"v":70.0826203549994,"d":"70.08"},{"v":6.13098481249895,"d":"6.13"},{"v":0.0104136811158527,"d":"0.01"},{"v":0.418969030940122,"d":"0.42"},"up","yes"]
[171910,0,"chr6","+",73461778,73473532,"ENST00000522205",4,882,"ENSG00000135297","MTO1","GO:0002098(tRNA wobble uridine modification);GO:0003723(RNA binding);GO:0005739(mitochondrion);GO:0008033(tRNA processing);GO:0030488(tRNA methylation);GO:0050660(flavin adenine dinucleotide binding);GO:0070899(mitochondrial tRNA wobble uridine modification)","NA","K03495","NA","mitochondrial tRNA translation optimization 1 [Source:HGNC Symbol;Acc:HGNC:19261]",{"v":0.041906,"d":"0.04"},0,0,{"v":1.262403,"d":"1.26"},0,{"v":2.345581,"d":"2.35"},{"v":0.0116147965179446,"d":"0.01"},{"v":-6.42789231028351,"d":"-6.43"},{"v":0.0104362676822074,"d":"0.01"},{"v":0.419413279750656,"d":"0.42"},"down","yes"]
[113209,0,"chr2","-",68131238,68261230,"ENST00000406334",15,2306,"ENSG00000273398","AC017083","GO:0000972(transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery);GO:0003723(RNA binding);GO:0005509(calcium ion binding);GO:0005643(nuclear pore);GO:0043130(ubiquitin binding)","NA","NA","NA","novel transcript",{"v":0.670909,"d":"0.67"},{"v":0.658125,"d":"0.66"},{"v":0.201548,"d":"0.20"},{"v":0.045653,"d":"0.05"},{"v":0.04613,"d":"0.05"},{"v":0.044195,"d":"0.04"},{"v":11.2561002515113,"d":"11.26"},{"v":3.49263517787385,"d":"3.49"},{"v":0.0104508556838108,"d":"0.01"},{"v":0.419509123175946,"d":"0.42"},"up","yes"]
[62739,0,"chr15","+",39581093,39599466,"ENST00000260356",22,7775,"ENSG00000137801","THBS1","GO:0000187(activation of MAPK activity);GO:0001666(response to hypoxia);GO:0001786(phosphatidylserine binding);GO:0001937(negative regulation of endothelial cell proliferation);GO:0001953(negative regulation of cell-matrix adhesion);GO:0001968(fibronectin binding);GO:0002040(sprouting angiogenesis);GO:0002544(chronic inflammatory response);GO:0002576(platelet degranulation);GO:0002581(negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II);GO:0002605(negative regulation of dendritic cell antigen processing and presentation);GO:0005178(integrin binding);GO:0005201(extracellular matrix structural constituent);GO:0005509(calcium ion binding);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0005577(fibrinogen complex);GO:0005615(extracellular space);GO:0005737(cytoplasm);GO:0005783(endoplasmic reticulum);GO:0005788(endoplasmic reticulum lumen);GO:0006954(inflammatory response);GO:0006955(immune response);GO:0006986(response to unfolded protein);GO:0007050(cell cycle arrest);GO:0007155(cell adhesion);GO:0008201(heparin binding);GO:0008284(positive regulation of cell population proliferation);GO:0009612(response to mechanical stimulus);GO:0009749(response to glucose);GO:0009897(external side of plasma membrane);GO:0009986(cell surface);GO:0010595(positive regulation of endothelial cell migration);GO:0010596(negative regulation of endothelial cell migration);GO:0010748(negative regulation of long-chain fatty acid import across plasma membrane);GO:0010751(negative regulation of nitric oxide mediated signal transduction);GO:0010754(negative regulation of cGMP-mediated signaling);GO:0010757(negative regulation of plasminogen activation);GO:0010759(positive regulation of macrophage chemotaxis);GO:0010763(positive regulation of fibroblast migration);GO:0016477(cell migration);GO:0016525(negative regulation of angiogenesis);GO:0016529(sarcoplasmic reticulum);GO:0017134(fibroblast growth factor binding);GO:0018149(peptide cross-linking);GO:0030141(secretory granule);GO:0030169(low-density lipoprotein particle binding);GO:0030194(positive regulation of blood coagulation);GO:0030198(extracellular matrix organization);GO:0030335(positive regulation of cell migration);GO:0030511(positive regulation of transforming growth factor beta receptor signaling pathway);GO:0031012(extracellular matrix);GO:0031091(platelet alpha granule);GO:0031093(platelet alpha granule lumen);GO:0032026(response to magnesium ion);GO:0032570(response to progesterone);GO:0032695(negative regulation of interleukin-12 production);GO:0032914(positive regulation of transforming growth factor beta1 production);GO:0033574(response to testosterone);GO:0034605(cellular response to heat);GO:0034976(response to endoplasmic reticulum stress);GO:0040037(negative regulation of fibroblast growth factor receptor signaling pathway);GO:0042327(positive regulation of phosphorylation);GO:0042493(response to drug);GO:0042535(positive regulation of tumor necrosis factor biosynthetic process);GO:0042802(identical protein binding);GO:0043032(positive regulation of macrophage activation);GO:0043066(negative regulation of apoptotic process);GO:0043154(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process);GO:0043236(laminin binding);GO:0043394(proteoglycan binding);GO:0043536(positive regulation of blood vessel endothelial cell migration);GO:0043537(negative regulation of blood vessel endothelial cell migration);GO:0043652(engulfment of apoptotic cell);GO:0045652(regulation of megakaryocyte differentiation);GO:0045727(positive regulation of translation);GO:0045766(positive regulation of angiogenesis);GO:0048266(behavioral response to pain);GO:0048661(positive regulation of smooth muscle cell proliferation);GO:0050431(transforming growth factor beta binding);GO:0050840(extracellular matrix binding);GO:0050921(positive regulation of chemotaxis);GO:0051592(response to calcium ion);GO:0051895(negative regulation of focal adhesion assembly);GO:0051897(positive regulation of protein kinase B signaling);GO:0051918(negative regulation of fibrinolysis);GO:0062023(collagen-containing extracellular matrix);GO:0070051(fibrinogen binding);GO:0070052(collagen V binding);GO:0070062(extracellular exosome);GO:0071356(cellular response to tumor necrosis factor);GO:0071363(cellular response to growth factor stimulus);GO:0071636(positive regulation of transforming growth factor beta production);GO:0090051(negative regulation of cell migration involved in sprouting angiogenesis);GO:1902043(positive regulation of extrinsic apoptotic signaling pathway via death domain receptors);GO:1903588(negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis);GO:1903671(negative regulation of sprouting angiogenesis);GO:2000353(positive regulation of endothelial cell apoptotic process);GO:2000379(positive regulation of reactive oxygen species metabolic process);GO:2001027(negative regulation of endothelial cell chemotaxis);GO:2001237(negative regulation of extrinsic apoptotic signaling pathway)","04015(Rap1 signaling pathway);04115(p53 signaling pathway);04145(Phagosome);04151(PI3K-Akt signaling pathway);04350(TGF-beta signaling pathway);04510(Focal adhesion);04512(ECM-receptor interaction);05144(Malaria);05165(Human papillomavirus infection);05205(Proteoglycans in cancer);05206(MicroRNAs in cancer);05219(Bladder cancer)","K16857","NA","thrombospondin 1 [Source:HGNC Symbol;Acc:HGNC:11785]",{"v":93.574158,"d":"93.57"},{"v":91.426765,"d":"91.43"},{"v":98.8508,"d":"98.85"},{"v":290.56665,"d":"290.57"},{"v":286.770508,"d":"286.77"},{"v":264.115906,"d":"264.12"},{"v":0.337335182607404,"d":"0.34"},{"v":-1.56774530180192,"d":"-1.57"},{"v":0.0104617469198295,"d":"0.01"},{"v":0.419509123175946,"d":"0.42"},"down","yes"]
[108805,0,"chr19","+",57499939,57518404,"ENST00000599847",5,5832,"ENSG00000152439","ZNF773","GO:0003676(nucleic acid binding);GO:0003677(DNA binding);GO:0005622(intracellular);GO:0005634(nucleus);GO:0006355(regulation of transcription, DNA-templated);GO:0046872(metal ion binding)","05168(Herpes simplex virus 1 infection)","K09228","NA","zinc finger protein 773 [Source:HGNC Symbol;Acc:HGNC:30487]",{"v":0.0072,"d":"0.01"},{"v":0.01045,"d":"0.01"},{"v":0.004411,"d":"0.00"},{"v":0.01442,"d":"0.01"},{"v":0.16435,"d":"0.16"},{"v":0.243626,"d":"0.24"},{"v":0.0522282407977348,"d":"0.05"},{"v":-4.25902607949988,"d":"-4.26"},{"v":0.0104845745907302,"d":"0.01"},{"v":0.41995873288226,"d":"0.42"},"down","yes"]
[63751,0,"chr15","+",44715817,44718145,"ENST00000623550",1,2329,"ENSG00000166710","B2M","GO:0000139(Golgi membrane);GO:0001895(retina homeostasis);GO:0001916(positive regulation of T cell mediated cytotoxicity);GO:0002237(response to molecule of bacterial origin);GO:0002376(immune system process);GO:0002474(antigen processing and presentation of peptide antigen via MHC class I);GO:0002479(antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent);GO:0002480(antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent);GO:0002481(antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent);GO:0002726(positive regulation of T cell cytokine production);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0005615(extracellular space);GO:0005788(endoplasmic reticulum lumen);GO:0005794(Golgi apparatus);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0005925(focal adhesion);GO:0006826(iron ion transport);GO:0006955(immune response);GO:0009897(external side of plasma membrane);GO:0009986(cell surface);GO:0010977(negative regulation of neuron projection development);GO:0012507(ER to Golgi transport vesicle membrane);GO:0016020(membrane);GO:0019885(antigen processing and presentation of endogenous peptide antigen via MHC class I);GO:0030670(phagocytic vesicle membrane);GO:0031901(early endosome membrane);GO:0031905(early endosome lumen);GO:0032092(positive regulation of protein binding);GO:0033077(T cell differentiation in thymus);GO:0034756(regulation of iron ion transport);GO:0035580(specific granule lumen);GO:0042026(protein refolding);GO:0042493(response to drug);GO:0042612(MHC class I protein complex);GO:0042802(identical protein binding);GO:0042824(MHC class I peptide loading complex);GO:0043312(neutrophil degranulation);GO:0044267(cellular protein metabolic process);GO:0045087(innate immune response);GO:0045646(regulation of erythrocyte differentiation);GO:0046686(response to cadmium ion);GO:0048260(positive regulation of receptor-mediated endocytosis);GO:0050690(regulation of defense response to virus by virus);GO:0050776(regulation of immune response);GO:0055038(recycling endosome membrane);GO:0055072(iron ion homeostasis);GO:0060333(interferon-gamma-mediated signaling pathway);GO:0070062(extracellular exosome);GO:0071281(cellular response to iron ion);GO:0071283(cellular response to iron(III) ion);GO:1900121(negative regulation of receptor binding);GO:1900122(positive regulation of receptor binding);GO:1904434(positive regulation of ferrous iron binding);GO:1904437(positive regulation of transferrin receptor binding);GO:1904724(tertiary granule lumen);GO:1990712(HFE-transferrin receptor complex)","04612(Antigen processing and presentation);05163(Human cytomegalovirus infection);05166(Human T-cell leukemia virus 1 infection);05168(Herpes simplex virus 1 infection);05169(Epstein-Barr virus infection);05170(Human immunodeficiency virus 1 infection)","NA","NA","beta-2-microglobulin [Source:HGNC Symbol;Acc:HGNC:914]",{"v":64.593689,"d":"64.59"},{"v":7.819476,"d":"7.82"},{"v":4.906371,"d":"4.91"},{"v":3.25344,"d":"3.25"},{"v":5.807979,"d":"5.81"},{"v":4.739428,"d":"4.74"},{"v":5.60252106265652,"d":"5.60"},{"v":2.48607616755236,"d":"2.49"},{"v":0.0105029516214943,"d":"0.01"},{"v":0.41995873288226,"d":"0.42"},"up","yes"]
[204978,0,"chrX","+",101623361,101627841,"ENST00000537169",5,3318,"ENSG00000102401","ARMCX3","GO:0005515(protein binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005739(mitochondrion);GO:0005741(mitochondrial outer membrane);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0031307(integral component of mitochondrial outer membrane);GO:0034613(cellular protein localization);GO:0045944(positive regulation of transcription by RNA polymerase II)","NA","NA","NA","armadillo repeat containing X-linked 3 [Source:HGNC Symbol;Acc:HGNC:24065]",{"v":2.203991,"d":"2.20"},{"v":3.74642,"d":"3.75"},{"v":35.549393,"d":"35.55"},{"v":1.954517,"d":"1.95"},{"v":2.455788,"d":"2.46"},{"v":2.412774,"d":"2.41"},{"v":6.08226930979401,"d":"6.08"},{"v":2.60460969721423,"d":"2.60"},{"v":0.0105137288134034,"d":"0.01"},{"v":0.41995873288226,"d":"0.42"},"up","yes"]
[98964,0,"chr19","+",10961043,11062271,"ENST00000645460",34,5457,"ENSG00000127616","SMARCA4","GO:0000122(negative regulation of transcription by RNA polymerase II);GO:0000166(nucleotide binding);GO:0000790(nuclear chromatin);GO:0000978(RNA polymerase II proximal promoter sequence-specific DNA binding);GO:0000980(RNA polymerase II distal enhancer sequence-specific DNA binding);GO:0001164(RNA polymerase I CORE element sequence-specific DNA binding);GO:0001188(RNA polymerase I preinitiation complex assembly);GO:0002039(p53 binding);GO:0003407(neural retina development);GO:0003713(transcription coactivator activity);GO:0003714(transcription corepressor activity);GO:0003723(RNA binding);GO:0004386(helicase activity);GO:0005515(protein binding);GO:0005524(ATP binding);GO:0005615(extracellular space);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005730(nucleolus);GO:0006325(chromatin organization);GO:0006337(nucleosome disassembly);GO:0006338(chromatin remodeling);GO:0006355(regulation of transcription, DNA-templated);GO:0006357(regulation of transcription by RNA polymerase II);GO:0007399(nervous system development);GO:0008094(DNA-dependent ATPase activity);GO:0008134(transcription factor binding);GO:0016020(membrane);GO:0016514(SWI/SNF complex);GO:0016787(hydrolase activity);GO:0016817(hydrolase activity, acting on acid anhydrides);GO:0016887(ATPase activity);GO:0030177(positive regulation of Wnt signaling pathway);GO:0030308(negative regulation of cell growth);GO:0030957(Tat protein binding);GO:0031492(nucleosomal DNA binding);GO:0032991(protein-containing complex);GO:0038111(interleukin-7-mediated signaling pathway);GO:0042393(histone binding);GO:0043044(ATP-dependent chromatin remodeling);GO:0043923(positive regulation by host of viral transcription);GO:0045892(negative regulation of transcription, DNA-templated);GO:0045893(positive regulation of transcription, DNA-templated);GO:0045944(positive regulation of transcription by RNA polymerase II);GO:0047485(protein N-terminus binding);GO:0050681(androgen receptor binding);GO:0051091(positive regulation of DNA-binding transcription factor activity);GO:0060766(negative regulation of androgen receptor signaling pathway);GO:0070182(DNA polymerase binding);GO:0070577(lysine-acetylated histone binding);GO:0071564(npBAF complex);GO:0071565(nBAF complex);GO:1901838(positive regulation of transcription of nucleolar large rRNA by RNA polymerase I);GO:1902661(positive regulation of glucose mediated signaling pathway);GO:1902895(positive regulation of pri-miRNA transcription by RNA polymerase II);GO:1904837(beta-catenin-TCF complex assembly)","04714(Thermogenesis);05225(Hepatocellular carcinoma)","NA","NA","SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 [Source:HGNC Symbol;Acc:HGNC:11100]",{"v":0.172962,"d":"0.17"},0,0,{"v":0.27671,"d":"0.28"},{"v":2.904856,"d":"2.90"},{"v":1.89769,"d":"1.90"},{"v":0.0340526250301225,"d":"0.03"},{"v":-4.87609017356479,"d":"-4.88"},{"v":0.0105191975481106,"d":"0.01"},{"v":0.41995873288226,"d":"0.42"},"down","yes"]
[143336,0,"chr3","-",120688597,120742993,"ENST00000473654",8,2370,"ENSG00000144840","RABL3","GO:0000166(nucleotide binding);GO:0003924(GTPase activity);GO:0005525(GTP binding);GO:0005623(cell);GO:0006886(intracellular protein transport);GO:0032482(Rab protein signal transduction)","NA","K07933","NA","RAB, member of RAS oncogene family like 3 [Source:HGNC Symbol;Acc:HGNC:18072]",0,{"v":0.48856,"d":"0.49"},{"v":0.930804,"d":"0.93"},0,0,{"v":0.019277,"d":"0.02"},{"v":73.6299216683094,"d":"73.63"},{"v":6.2022202615778,"d":"6.20"},{"v":0.0105422043999425,"d":"0.01"},{"v":0.420415242425806,"d":"0.42"},"up","yes"]
[7199,0,"chr1","+",66924959,66985684,"ENST00000401041",14,2552,"ENSG00000198160","MIER1","GO:0000122(negative regulation of transcription by RNA polymerase II);GO:0000981(DNA-binding transcription factor activity, RNA polymerase II-specific);GO:0001103(RNA polymerase II repressing transcription factor binding);GO:0003677(DNA binding);GO:0003714(transcription corepressor activity);GO:0004407(histone deacetylase activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0006355(regulation of transcription, DNA-templated);GO:0016575(histone deacetylation);GO:0017053(transcriptional repressor complex);GO:0031937(positive regulation of chromatin silencing);GO:0032991(protein-containing complex);GO:0042826(histone deacetylase binding);GO:0043123(positive regulation of I-kappaB kinase/NF-kappaB signaling)","NA","NA","NA","MIER1 transcriptional regulator [Source:HGNC Symbol;Acc:HGNC:29657]",{"v":0.035656,"d":"0.04"},{"v":0.253027,"d":"0.25"},{"v":0.097979,"d":"0.10"},{"v":1.25198,"d":"1.25"},{"v":2.426165,"d":"2.43"},{"v":0.158696,"d":"0.16"},{"v":0.100776133282562,"d":"0.10"},{"v":-3.31077408771485,"d":"-3.31"},{"v":0.0105635357691329,"d":"0.01"},{"v":0.420804007119078,"d":"0.42"},"down","yes"]
[85477,0,"chr17","+",41688895,41691622,"ENST00000482111",3,1428,"ENSG00000173812","EIF1","GO:0003723(RNA binding);GO:0003743(translation initiation factor activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0006412(translation);GO:0006413(translational initiation);GO:0006446(regulation of translational initiation);GO:0008135(translation factor activity, RNA binding);GO:0009048(dosage compensation by inactivation of X chromosome);GO:0016282(eukaryotic 43S preinitiation complex);GO:0043024(ribosomal small subunit binding)","03013(RNA transport)","K03113","NA","eukaryotic translation initiation factor 1 [Source:HGNC Symbol;Acc:HGNC:3249]",{"v":9.097837,"d":"9.10"},{"v":7.955221,"d":"7.96"},{"v":7.388476,"d":"7.39"},{"v":6.637377,"d":"6.64"},{"v":7.449294,"d":"7.45"},{"v":147.453293,"d":"147.45"},{"v":0.151303327020675,"d":"0.15"},{"v":-2.72448438344999,"d":"-2.72"},{"v":0.0105998527082376,"d":"0.01"},{"v":0.421788224414318,"d":"0.42"},"down","yes"]
[117766,0,"chr2","-",144389285,144517551,"ENST00000558170",9,4012,"ENSG00000169554","ZEB2","GO:0000122(negative regulation of transcription by RNA polymerase II);GO:0000790(nuclear chromatin);GO:0000981(DNA-binding transcription factor activity, RNA polymerase II-specific);GO:0001227(DNA-binding transcription repressor activity, RNA polymerase II-specific);GO:0001228(DNA-binding transcription activator activity, RNA polymerase II-specific);GO:0001755(neural crest cell migration);GO:0001756(somitogenesis);GO:0001843(neural tube closure);GO:0003676(nucleic acid binding);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005730(nucleolus);GO:0005829(cytosol);GO:0007399(nervous system development);GO:0007417(central nervous system development);GO:0019208(phosphatase regulator activity);GO:0021540(corpus callosum morphogenesis);GO:0021766(hippocampus development);GO:0021846(cell proliferation in forebrain);GO:0021957(corticospinal tract morphogenesis);GO:0030177(positive regulation of Wnt signaling pathway);GO:0043507(positive regulation of JUN kinase activity);GO:0043565(sequence-specific DNA binding);GO:0045636(positive regulation of melanocyte differentiation);GO:0045944(positive regulation of transcription by RNA polymerase II);GO:0046872(metal ion binding);GO:0048023(positive regulation of melanin biosynthetic process);GO:0048066(developmental pigmentation);GO:0048598(embryonic morphogenesis);GO:0048668(collateral sprouting);GO:0050772(positive regulation of axonogenesis);GO:0061373(mammillary axonal complex development);GO:0070412(R-SMAD binding);GO:0097324(melanocyte migration);GO:1902748(positive regulation of lens fiber cell differentiation);GO:1903056(regulation of melanosome organization)","05206(MicroRNAs in cancer)","K09299","NA","zinc finger E-box binding homeobox 2 [Source:HGNC Symbol;Acc:HGNC:14881]",{"v":0.092682,"d":"0.09"},{"v":0.209127,"d":"0.21"},{"v":0.304857,"d":"0.30"},{"v":0.049419,"d":"0.05"},{"v":0.153004,"d":"0.15"},{"v":9.962172,"d":"9.96"},{"v":0.0596842274581525,"d":"0.06"},{"v":-4.06650646388479,"d":"-4.07"},{"v":0.0106404653617286,"d":"0.01"},{"v":0.422941035658206,"d":"0.42"},"down","yes"]
[23284,0,"chr10","+",95756163,95877266,"ENST00000371205",10,12493,"ENSG00000138185","ENTPD1","GO:0000166(nucleotide binding);GO:0005515(protein binding);GO:0005524(ATP binding);GO:0005886(plasma membrane);GO:0005887(integral component of plasma membrane);GO:0007155(cell adhesion);GO:0007596(blood coagulation);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016787(hydrolase activity);GO:0034656(nucleobase-containing small molecule catabolic process);GO:0070062(extracellular exosome);GO:0102485(dATP phosphohydrolase activity);GO:0102486(dCTP phosphohydrolase activity);GO:0102487(dUTP phosphohydrolase activity);GO:0102488(dTTP phosphohydrolase activity);GO:0102489(GTP phosphohydrolase activity);GO:0102490(8-oxo-dGTP phosphohydrolase activity);GO:0102491(dGTP phosphohydrolase activity)","00230(Purine metabolism);00240(Pyrimidine metabolism);05169(Epstein-Barr virus infection)","NA","NA","ectonucleoside triphosphate diphosphohydrolase 1 [Source:HGNC Symbol;Acc:HGNC:3363]",{"v":7.78243,"d":"7.78"},{"v":3.513822,"d":"3.51"},{"v":7.958273,"d":"7.96"},{"v":1.844972,"d":"1.84"},{"v":1.829003,"d":"1.83"},{"v":1.877847,"d":"1.88"},{"v":3.46814523232193,"d":"3.47"},{"v":1.7941643142355,"d":"1.79"},{"v":0.0106843979909534,"d":"0.01"},{"v":0.424016356567153,"d":"0.42"},"up","yes"]
[91306,0,"chr17","+",80101581,80119881,"ENST00000302262",20,3751,"ENSG00000171298","GAA","GO:0000023(maltose metabolic process);GO:0002026(regulation of the force of heart contraction);GO:0002086(diaphragm contraction);GO:0003007(heart morphogenesis);GO:0003824(catalytic activity);GO:0004553(hydrolase activity, hydrolyzing O-glycosyl compounds);GO:0004558(alpha-1,4-glucosidase activity);GO:0005764(lysosome);GO:0005765(lysosomal membrane);GO:0005886(plasma membrane);GO:0005975(carbohydrate metabolic process);GO:0005977(glycogen metabolic process);GO:0005980(glycogen catabolic process);GO:0005985(sucrose metabolic process);GO:0006006(glucose metabolic process);GO:0006941(striated muscle contraction);GO:0007040(lysosome organization);GO:0007626(locomotory behavior);GO:0008152(metabolic process);GO:0009888(tissue development);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016787(hydrolase activity);GO:0016798(hydrolase activity, acting on glycosyl bonds);GO:0030246(carbohydrate binding);GO:0032450(maltose alpha-glucosidase activity);GO:0035577(azurophil granule membrane);GO:0043181(vacuolar sequestering);GO:0043202(lysosomal lumen);GO:0043312(neutrophil degranulation);GO:0046716(muscle cell cellular homeostasis);GO:0050884(neuromuscular process controlling posture);GO:0050885(neuromuscular process controlling balance);GO:0060048(cardiac muscle contraction);GO:0070062(extracellular exosome);GO:0070821(tertiary granule membrane);GO:0090599(alpha-glucosidase activity);GO:0101003(ficolin-1-rich granule membrane)","00052(Galactose metabolism);00500(Starch and sucrose metabolism);04142(Lysosome)","NA","NA","glucosidase alpha, acid [Source:HGNC Symbol;Acc:HGNC:4065]",{"v":3.37211,"d":"3.37"},{"v":36.92807,"d":"36.93"},{"v":0.294957,"d":"0.29"},{"v":2.798419,"d":"2.80"},{"v":0.533436,"d":"0.53"},{"v":0.575043,"d":"0.58"},{"v":10.3906313909398,"d":"10.39"},{"v":3.37721141774368,"d":"3.38"},{"v":0.0106908610684149,"d":"0.01"},{"v":0.424016356567153,"d":"0.42"},"up","yes"]
[172187,0,"chr6","+",83512534,83525704,"ENST00000369700",2,2444,"ENSG00000146250","PRSS35","GO:0004252(serine-type endopeptidase activity);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0006508(proteolysis)","NA","NA","NA","serine protease 35 [Source:HGNC Symbol;Acc:HGNC:21387]",{"v":32.858967,"d":"32.86"},{"v":36.364056,"d":"36.36"},{"v":32.805859,"d":"32.81"},{"v":9.648094,"d":"9.65"},{"v":10.941378,"d":"10.94"},{"v":10.756899,"d":"10.76"},{"v":3.25488657044224,"d":"3.25"},{"v":1.70260726778051,"d":"1.70"},{"v":0.0107389970880418,"d":"0.01"},{"v":0.425461029671275,"d":"0.43"},"up","yes"]
[206360,0,"chrX","+",136147533,136211359,"ENST00000370690",7,2373,"ENSG00000022267","FHL1","GO:0003254(regulation of membrane depolarization);GO:0003674(molecular_function);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0005925(focal adhesion);GO:0007275(multicellular organism development);GO:0007517(muscle organ development);GO:0009887(animal organ morphogenesis);GO:0010972(negative regulation of G2/M transition of mitotic cell cycle);GO:0030154(cell differentiation);GO:0030308(negative regulation of cell growth);GO:0043268(positive regulation of potassium ion transport);GO:0044325(ion channel binding);GO:0046872(metal ion binding);GO:1901016(regulation of potassium ion transmembrane transporter activity);GO:2000134(negative regulation of G1/S transition of mitotic cell cycle)","04630(Jak-STAT signaling pathway)","K14365","NA","four and a half LIM domains 1 [Source:HGNC Symbol;Acc:HGNC:3702]",{"v":0.446455,"d":"0.45"},{"v":13.462041,"d":"13.46"},{"v":0.397339,"d":"0.40"},{"v":0.371951,"d":"0.37"},{"v":0.627881,"d":"0.63"},{"v":0.102076,"d":"0.10"},{"v":12.9827853142005,"d":"12.98"},{"v":3.69852802582889,"d":"3.70"},{"v":0.0108461417883542,"d":"0.01"},{"v":0.429237833519507,"d":"0.43"},"up","yes"]
[52843,0,"chr13","-",95984910,96053400,"ENST00000397618",10,1547,"ENSG00000102595","UGGT2","GO:0003980(UDP-glucose:glycoprotein glucosyltransferase activity);GO:0005515(protein binding);GO:0005783(endoplasmic reticulum);GO:0005788(endoplasmic reticulum lumen);GO:0005793(endoplasmic reticulum-Golgi intermediate compartment);GO:0006486(protein glycosylation);GO:0016740(transferase activity);GO:0016757(transferase activity, transferring glycosyl groups);GO:0018279(protein N-linked glycosylation via asparagine);GO:0032991(protein-containing complex);GO:0044322(endoplasmic reticulum quality control compartment);GO:0051082(unfolded protein binding);GO:0071712(ER-associated misfolded protein catabolic process);GO:0097359(UDP-glucosylation);GO:1904380(endoplasmic reticulum mannose trimming)","04141(Protein processing in endoplasmic reticulum)","K11718","EC:2.4.1.-","UDP-glucose glycoprotein glucosyltransferase 2 [Source:HGNC Symbol;Acc:HGNC:15664]",{"v":0.054287,"d":"0.05"},{"v":0.050756,"d":"0.05"},0,{"v":1.279538,"d":"1.28"},{"v":0.009989,"d":"0.01"},{"v":1.347611,"d":"1.35"},{"v":0.0398321968740354,"d":"0.04"},{"v":-4.64992113859703,"d":"-4.65"},{"v":0.0108875719825526,"d":"0.01"},{"v":0.430408585556187,"d":"0.43"},"down","yes"]
[2891,0,"chr1","-",24899511,24965010,"ENST00000399916",6,4340,"ENSG00000020633","RUNX3","GO:0000122(negative regulation of transcription by RNA polymerase II);GO:0000790(nuclear chromatin);GO:0000977(RNA polymerase II regulatory region sequence-specific DNA binding);GO:0000981(DNA-binding transcription factor activity, RNA polymerase II-specific);GO:0002062(chondrocyte differentiation);GO:0003677(DNA binding);GO:0003700(DNA-binding transcription factor activity);GO:0005515(protein binding);GO:0005524(ATP binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005730(nucleolus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0006355(regulation of transcription, DNA-templated);GO:0006366(transcription by RNA polymerase II);GO:0006468(protein phosphorylation);GO:0016513(core-binding factor complex);GO:0030097(hemopoiesis);GO:0030182(neuron differentiation);GO:0043231(intracellular membrane-bounded organelle);GO:0043371(negative regulation of CD4-positive, alpha-beta T cell differentiation);GO:0043378(positive regulation of CD8-positive, alpha-beta T cell differentiation);GO:0045786(negative regulation of cell cycle);GO:0045893(positive regulation of transcription, DNA-templated);GO:0048935(peripheral nervous system neuron development);GO:0050680(negative regulation of epithelial cell proliferation);GO:0071559(response to transforming growth factor beta)","04658(Th1 and Th2 cell differentiation);05169(Epstein-Barr virus infection)","NA","NA","runt related transcription factor 3 [Source:HGNC Symbol;Acc:HGNC:10473]",{"v":0.077773,"d":"0.08"},{"v":0.327545,"d":"0.33"},{"v":0.285993,"d":"0.29"},{"v":0.755467,"d":"0.76"},{"v":6.771245,"d":"6.77"},{"v":0.117107,"d":"0.12"},{"v":0.0904405245597783,"d":"0.09"},{"v":-3.46688682995423,"d":"-3.47"},{"v":0.0109769287789246,"d":"0.01"},{"v":0.433251989676161,"d":"0.43"},"down","yes"]
[182820,0,"chr7","+",107580265,107618664,"ENST00000445771",9,1157,"ENSG00000075790","BCAP29","GO:0001649(osteoblast differentiation);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005887(integral component of plasma membrane);GO:0006886(intracellular protein transport);GO:0006888(endoplasmic reticulum to Golgi vesicle-mediated transport);GO:0006915(apoptotic process);GO:0015031(protein transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016192(vesicle-mediated transport);GO:0070973(protein localization to endoplasmic reticulum exit site)","NA","NA","NA","B cell receptor associated protein 29 [Source:HGNC Symbol;Acc:HGNC:24131]",{"v":1.315797,"d":"1.32"},{"v":0.337836,"d":"0.34"},{"v":6.197941,"d":"6.20"},{"v":0.206529,"d":"0.21"},{"v":0.275135,"d":"0.28"},{"v":0.339587,"d":"0.34"},{"v":9.5605046447432,"d":"9.56"},{"v":3.25708677189361,"d":"3.26"},{"v":0.0109833493666871,"d":"0.01"},{"v":0.433251989676161,"d":"0.43"},"up","yes"]
[23991,0,"chr10","+",102776249,102816267,"ENST00000369889",4,4107,"ENSG00000166272","WBP1L","GO:0005515(protein binding);GO:0016020(membrane);GO:0016021(integral component of membrane)","NA","NA","NA","WW domain binding protein 1 like [Source:HGNC Symbol;Acc:HGNC:23510]",0,{"v":0.499832,"d":"0.50"},{"v":0.290917,"d":"0.29"},{"v":0.008887,"d":"0.01"},{"v":0.006316,"d":"0.01"},0,{"v":52.012694862856,"d":"52.01"},{"v":5.70079188314945,"d":"5.70"},{"v":0.0109992721659143,"d":"0.01"},{"v":0.433409498685104,"d":"0.43"},"up","yes"]
[98812,0,"chr19","-",10553091,10559936,"ENST00000537363",9,2255,"ENSG00000129347","KRI1","GO:0000447(endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA));GO:0003723(RNA binding);GO:0005730(nucleolus);GO:0030686(90S preribosome)","NA","K14786","NA","KRI1 homolog [Source:HGNC Symbol;Acc:HGNC:25769]",{"v":0.05506,"d":"0.06"},{"v":0.03228,"d":"0.03"},{"v":0.042538,"d":"0.04"},{"v":0.104088,"d":"0.10"},{"v":0.722204,"d":"0.72"},{"v":0.810976,"d":"0.81"},{"v":0.0793260480263463,"d":"0.08"},{"v":-3.65606151315372,"d":"-3.66"},{"v":0.0110721053350698,"d":"0.01"},{"v":0.435802641585748,"d":"0.44"},"down","yes"]
[103965,0,"chr19","-",40393768,40413364,"ENST00000291825",6,5502,"ENSG00000105227","PRX","GO:0003674(molecular_function);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005886(plasma membrane);GO:0008366(axon ensheathment);GO:0016020(membrane);GO:0030054(cell junction);GO:0030315(T-tubule);GO:0043484(regulation of RNA splicing)","NA","NA","NA","periaxin [Source:HGNC Symbol;Acc:HGNC:13797]",{"v":0.30526,"d":"0.31"},{"v":0.193236,"d":"0.19"},{"v":0.22853,"d":"0.23"},{"v":0.834877,"d":"0.83"},{"v":1.901757,"d":"1.90"},{"v":1.52381,"d":"1.52"},{"v":0.170645594684498,"d":"0.17"},{"v":-2.55092492398333,"d":"-2.55"},{"v":0.011083997820678,"d":"0.01"},{"v":0.435802641585748,"d":"0.44"},"down","yes"]
[70690,0,"chr16","+",3401244,3405079,"ENST00000344823",3,1557,"ENSG00000103343","ZNF174","GO:0000122(negative regulation of transcription by RNA polymerase II);GO:0000981(DNA-binding transcription factor activity, RNA polymerase II-specific);GO:0001227(DNA-binding transcription repressor activity, RNA polymerase II-specific);GO:0003676(nucleic acid binding);GO:0003677(DNA binding);GO:0003700(DNA-binding transcription factor activity);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0006355(regulation of transcription, DNA-templated);GO:0015629(actin cytoskeleton);GO:0042803(protein homodimerization activity);GO:0043565(sequence-specific DNA binding);GO:0044212(transcription regulatory region DNA binding);GO:0045892(negative regulation of transcription, DNA-templated);GO:0046872(metal ion binding)","NA","K09230","NA","zinc finger protein 174 [Source:HGNC Symbol;Acc:HGNC:12963]",{"v":0.281326,"d":"0.28"},{"v":0.072158,"d":"0.07"},{"v":0.310629,"d":"0.31"},{"v":0.334403,"d":"0.33"},{"v":2.743143,"d":"2.74"},{"v":2.528408,"d":"2.53"},{"v":0.118465652768467,"d":"0.12"},{"v":-3.07745926161529,"d":"-3.08"},{"v":0.0111042130365421,"d":"0.01"},{"v":0.436125469856836,"d":"0.44"},"down","yes"]
[120738,0,"chr2","+",200469740,200477882,"ENST00000462190",3,745,"ENSG00000196141","SPATS2L","GO:0003723(RNA binding);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005730(nucleolus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0032991(protein-containing complex)","NA","NA","NA","spermatogenesis associated serine rich 2 like [Source:HGNC Symbol;Acc:HGNC:24574]",{"v":40.171604,"d":"40.17"},{"v":2.676582,"d":"2.68"},{"v":2.560845,"d":"2.56"},{"v":1.508137,"d":"1.51"},{"v":1.333689,"d":"1.33"},{"v":2.143044,"d":"2.14"},{"v":9.10937115712145,"d":"9.11"},{"v":3.18735146458542,"d":"3.19"},{"v":0.0112294788766824,"d":"0.01"},{"v":0.440569079470703,"d":"0.44"},"up","yes"]
[66059,0,"chr15","-",72208666,72210026,"ENST00000568743",2,580,"ENSG00000067225","PKM","GO:0000166(nucleotide binding);GO:0000287(magnesium ion binding);GO:0001666(response to hypoxia);GO:0001889(liver development);GO:0003723(RNA binding);GO:0003824(catalytic activity);GO:0004743(pyruvate kinase activity);GO:0005515(protein binding);GO:0005524(ATP binding);GO:0005576(extracellular region);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005739(mitochondrion);GO:0005829(cytosol);GO:0005929(cilium);GO:0006006(glucose metabolic process);GO:0006096(glycolytic process);GO:0006754(ATP biosynthetic process);GO:0007584(response to nutrient);GO:0008152(metabolic process);GO:0009629(response to gravity);GO:0010033(response to organic substance);GO:0012501(programmed cell death);GO:0014870(response to muscle inactivity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0016740(transferase activity);GO:0023026(MHC class II protein complex binding);GO:0030955(potassium ion binding);GO:0031100(animal organ regeneration);GO:0031982(vesicle);GO:0032868(response to insulin);GO:0032869(cellular response to insulin stimulus);GO:0034774(secretory granule lumen);GO:0042802(identical protein binding);GO:0042866(pyruvate biosynthetic process);GO:0043312(neutrophil degranulation);GO:0043403(skeletal muscle tissue regeneration);GO:0043531(ADP binding);GO:0045296(cadherin binding);GO:0046872(metal ion binding);GO:0051289(protein homotetramerization);GO:0061621(canonical glycolysis);GO:0062023(collagen-containing extracellular matrix);GO:0070062(extracellular exosome);GO:0070324(thyroid hormone binding);GO:1902912(pyruvate kinase complex);GO:1903561(extracellular vesicle);GO:1903672(positive regulation of sprouting angiogenesis);GO:1904813(ficolin-1-rich granule lumen)","00010(Glycolysis / Gluconeogenesis);00230(Purine metabolism);00620(Pyruvate metabolism);04922(Glucagon signaling pathway);04930(Type II diabetes mellitus);05165(Human papillomavirus infection);05203(Viral carcinogenesis);05230(Central carbon metabolism in cancer)","K00873","EC:2.7.1.40","pyruvate kinase M1/2 [Source:HGNC Symbol;Acc:HGNC:9021]",{"v":0.308196,"d":"0.31"},{"v":0.348751,"d":"0.35"},{"v":0.453155,"d":"0.45"},{"v":3.439103,"d":"3.44"},{"v":0.148055,"d":"0.15"},{"v":8.246036,"d":"8.25"},{"v":0.0938125412293587,"d":"0.09"},{"v":-3.41407538899606,"d":"-3.41"},{"v":0.0112525791550103,"d":"0.01"},{"v":0.440999137757847,"d":"0.44"},"down","yes"]
[141048,0,"chr3","-",56727418,56801967,"ENST00000296315",10,3602,"ENSG00000163947","ARHGEF3","GO:0005085(guanyl-nucleotide exchange factor activity);GO:0005089(Rho guanyl-nucleotide exchange factor activity);GO:0005515(protein binding);GO:0005622(intracellular);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0007186(G protein-coupled receptor signaling pathway);GO:0007266(Rho protein signal transduction);GO:0035023(regulation of Rho protein signal transduction);GO:0035556(intracellular signal transduction);GO:0043065(positive regulation of apoptotic process);GO:0051056(regulation of small GTPase mediated signal transduction)","NA","K20683","NA","Rho guanine nucleotide exchange factor 3 [Source:HGNC Symbol;Acc:HGNC:683]",{"v":1.763715,"d":"1.76"},{"v":0.364762,"d":"0.36"},{"v":1.124561,"d":"1.12"},{"v":0.138171,"d":"0.14"},0,0,{"v":23.5435655817791,"d":"23.54"},{"v":4.55726092238385,"d":"4.56"},{"v":0.0112683857836558,"d":"0.01"},{"v":0.441142732241611,"d":"0.44"},"up","yes"]
[41929,0,"chr12","-",45919131,45923100,"ENST00000547654",3,416,"ENSG00000139218","SCAF11","GO:0000245(spliceosomal complex assembly);GO:0000375(RNA splicing, via transesterification reactions);GO:0003723(RNA binding);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005730(nucleolus);GO:0006397(mRNA processing);GO:0008380(RNA splicing);GO:0016604(nuclear body);GO:0046872(metal ion binding)","NA","NA","NA","SR-related CTD associated factor 11 [Source:HGNC Symbol;Acc:HGNC:10784]",{"v":0.188938,"d":"0.19"},{"v":3.538358,"d":"3.54"},{"v":3.255651,"d":"3.26"},{"v":0.198517,"d":"0.20"},{"v":0.106997,"d":"0.11"},{"v":0.101774,"d":"0.10"},{"v":17.1449858576732,"d":"17.14"},{"v":4.0997148091304,"d":"4.10"},{"v":0.0113454554085278,"d":"0.01"},{"v":0.443681803005184,"d":"0.44"},"up","yes"]
[134755,0,"chr22","+",39021113,39033261,"ENST00000427494",4,1961,"ENSG00000243811","APOBEC3D","GO:0000932(P-body);GO:0002376(immune system process);GO:0003723(RNA binding);GO:0003824(catalytic activity);GO:0004126(cytidine deaminase activity);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0008270(zinc ion binding);GO:0009972(cytidine deamination);GO:0010529(negative regulation of transposition);GO:0016554(cytidine to uridine editing);GO:0016787(hydrolase activity);GO:0045087(innate immune response);GO:0045869(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate);GO:0046872(metal ion binding);GO:0051607(defense response to virus);GO:0070383(DNA cytosine deamination);GO:0080111(DNA demethylation)","05170(Human immunodeficiency virus 1 infection)","K18750","EC:3.5.4.-","apolipoprotein B mRNA editing enzyme catalytic subunit 3D [Source:HGNC Symbol;Acc:HGNC:17354]",{"v":0.00278,"d":"0.00"},{"v":0.002982,"d":"0.00"},{"v":0.051899,"d":"0.05"},{"v":0.966995,"d":"0.97"},{"v":0.791352,"d":"0.79"},{"v":0.002413,"d":"0.00"},{"v":0.0327477907267316,"d":"0.03"},{"v":-4.93245860877651,"d":"-4.93"},{"v":0.0113968503187605,"d":"0.01"},{"v":0.444434621135592,"d":"0.44"},"down","yes"]
[97207,0,"chr19","+",3572944,3579083,"ENST00000333651",10,1585,"ENSG00000064961","HMG20B","GO:0000981(DNA-binding transcription factor activity, RNA polymerase II-specific);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005694(chromosome);GO:0006325(chromatin organization);GO:0006357(regulation of transcription by RNA polymerase II);GO:0007049(cell cycle);GO:0007596(blood coagulation);GO:0016604(nuclear body);GO:0033234(negative regulation of protein sumoylation);GO:0035914(skeletal muscle cell differentiation);GO:0045666(positive regulation of neuron differentiation);GO:0046982(protein heterodimerization activity)","NA","NA","NA","high mobility group 20B [Source:HGNC Symbol;Acc:HGNC:5002]",{"v":25.672953,"d":"25.67"},{"v":30.225618,"d":"30.23"},{"v":29.931347,"d":"29.93"},{"v":7.760253,"d":"7.76"},{"v":8.562138,"d":"8.56"},{"v":8.093033,"d":"8.09"},{"v":3.51539739797269,"d":"3.52"},{"v":1.81368778792584,"d":"1.81"},{"v":0.0113976002241312,"d":"0.01"},{"v":0.444434621135592,"d":"0.44"},"up","yes"]
[7818,0,"chr1","+",84078062,84238498,"ENST00000370689",10,4513,"ENSG00000142875","PRKACB","GO:0000166(nucleotide binding);GO:0000287(magnesium ion binding);GO:0001843(neural tube closure);GO:0002223(stimulatory C-type lectin receptor signaling pathway);GO:0003091(renal water homeostasis);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0004691(cAMP-dependent protein kinase activity);GO:0005515(protein binding);GO:0005524(ATP binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0005813(centrosome);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0005952(cAMP-dependent protein kinase complex);GO:0006468(protein phosphorylation);GO:0007165(signal transduction);GO:0007186(G protein-coupled receptor signaling pathway);GO:0007188(adenylate cyclase-modulating G protein-coupled receptor signaling pathway);GO:0007596(blood coagulation);GO:0016020(membrane);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0016740(transferase activity);GO:0031625(ubiquitin protein ligase binding);GO:0034199(activation of protein kinase A activity);GO:0034237(protein kinase A regulatory subunit binding);GO:0034380(high-density lipoprotein particle assembly);GO:0045171(intercellular bridge);GO:0048471(perinuclear region of cytoplasm);GO:0051447(negative regulation of meiotic cell cycle);GO:0070062(extracellular exosome);GO:0070613(regulation of protein processing);GO:0071377(cellular response to glucagon stimulus);GO:0097338(response to clozapine);GO:0097546(ciliary base);GO:1901621(negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning)","01522(Endocrine resistance);04010(MAPK signaling pathway);04014(Ras signaling pathway);04020(Calcium signaling pathway);04024(cAMP signaling pathway);04062(Chemokine signaling pathway);04114(Oocyte meiosis);04140(Autophagy - animal);04211(Longevity regulating pathway);04213(Longevity regulating pathway - multiple species);04261(Adrenergic signaling in cardiomyocytes);04270(Vascular smooth muscle contraction);04310(Wnt signaling pathway);04340(Hedgehog signaling pathway);04371(Apelin signaling pathway);04530(Tight junction);04540(Gap junction);04611(Platelet activation);04713(Circadian entrainment);04714(Thermogenesis);04720(Long-term potentiation);04723(Retrograde endocannabinoid signaling);04724(Glutamatergic synapse);04725(Cholinergic synapse);04726(Serotonergic synapse);04727(GABAergic synapse);04728(Dopaminergic synapse);04740(Olfactory transduction);04742(Taste transduction);04750(Inflammatory mediator regulation of TRP channels);04910(Insulin signaling pathway);04911(Insulin secretion);04912(GnRH signaling pathway);04913(Ovarian steroidogenesis);04914(Progesterone-mediated oocyte maturation);04915(Estrogen signaling pathway);04916(Melanogenesis);04918(Thyroid hormone synthesis);04919(Thyroid hormone signaling pathway);04921(Oxytocin signaling pathway);04922(Glucagon signaling pathway);04923(Regulation of lipolysis in adipocytes);04924(Renin secretion);04925(Aldosterone synthesis and secretion);04926(Relaxin signaling pathway);04927(Cortisol synthesis and secretion);04928(Parathyroid hormone synthesis, secretion and action);04934(Cushing syndrome);04961(Endocrine and other factor-regulated calcium reabsorption);04962(Vasopressin-regulated water reabsorption);04970(Salivary secretion);04971(Gastric acid secretion);04976(Bile secretion);05012(Parkinson disease);05020(Prion diseases);05030(Cocaine addiction);05031(Amphetamine addiction);05032(Morphine addiction);05110(Vibrio cholerae infection);05146(Amoebiasis);05163(Human cytomegalovirus infection);05165(Human papillomavirus infection);05166(Human T-cell leukemia virus 1 infection);05200(Pathways in cancer);05203(Viral carcinogenesis);05205(Proteoglycans in cancer);05414(Dilated cardiomyopathy (DCM))","NA","NA","protein kinase cAMP-activated catalytic subunit beta [Source:HGNC Symbol;Acc:HGNC:9381]",{"v":8.740807,"d":"8.74"},{"v":10.073244,"d":"10.07"},{"v":10.062714,"d":"10.06"},{"v":1.94677,"d":"1.95"},{"v":4.116863,"d":"4.12"},{"v":0.786194,"d":"0.79"},{"v":4.21569260070364,"d":"4.22"},{"v":2.07576967257072,"d":"2.08"},{"v":0.0114014056399222,"d":"0.01"},{"v":0.444434621135592,"d":"0.44"},"up","yes"]
[138667,0,"chr3","+",41199603,41238271,"ENST00000643865",12,4145,"ENSG00000168036","CTNNB1","GO:0000122(negative regulation of transcription by RNA polymerase II);GO:0000209(protein polyubiquitination);GO:0000578(embryonic axis specification);GO:0000904(cell morphogenesis involved in differentiation);GO:0000922(spindle pole);GO:0001085(RNA polymerase II transcription factor binding);GO:0001102(RNA polymerase II activating transcription factor binding);GO:0001501(skeletal system development);GO:0001569(branching involved in blood vessel morphogenesis);GO:0001570(vasculogenesis);GO:0001658(branching involved in ureteric bud morphogenesis);GO:0001701(in utero embryonic development);GO:0001702(gastrulation with mouth forming second);GO:0001706(endoderm formation);GO:0001708(cell fate specification);GO:0001709(cell fate determination);GO:0001711(endodermal cell fate commitment);GO:0001764(neuron migration);GO:0001822(kidney development);GO:0001837(epithelial to mesenchymal transition);GO:0001840(neural plate development);GO:0001894(tissue homeostasis);GO:0001944(vasculature development);GO:0002052(positive regulation of neuroblast proliferation);GO:0002053(positive regulation of mesenchymal cell proliferation);GO:0002089(lens morphogenesis in camera-type eye);GO:0003266(regulation of secondary heart field cardioblast proliferation);GO:0003338(metanephros morphogenesis);GO:0003340(negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis);GO:0003682(chromatin binding);GO:0003700(DNA-binding transcription factor activity);GO:0003713(transcription coactivator activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005667(transcription factor complex);GO:0005719(nuclear euchromatin);GO:0005737(cytoplasm);GO:0005813(centrosome);GO:0005815(microtubule organizing center);GO:0005829(cytosol);GO:0005856(cytoskeleton);GO:0005886(plasma membrane);GO:0005911(cell-cell junction);GO:0005912(adherens junction);GO:0005913(cell-cell adherens junction);GO:0005916(fascia adherens);GO:0005923(bicellular tight junction);GO:0005925(focal adhesion);GO:0005938(cell cortex);GO:0006355(regulation of transcription, DNA-templated);GO:0006357(regulation of transcription by RNA polymerase II);GO:0007155(cell adhesion);GO:0007160(cell-matrix adhesion);GO:0007223(Wnt signaling pathway, calcium modulating pathway);GO:0007268(chemical synaptic transmission);GO:0007398(ectoderm development);GO:0007399(nervous system development);GO:0007403(glial cell fate determination);GO:0007507(heart development);GO:0008022(protein C-terminus binding);GO:0008134(transcription factor binding);GO:0008283(cell population proliferation);GO:0008284(positive regulation of cell population proliferation);GO:0008285(negative regulation of cell population proliferation);GO:0009948(anterior/posterior axis specification);GO:0009950(dorsal/ventral axis specification);GO:0009953(dorsal/ventral pattern formation);GO:0009954(proximal/distal pattern formation);GO:0009987(cellular process);GO:0010468(regulation of gene expression);GO:0010628(positive regulation of gene expression);GO:0010629(negative regulation of gene expression);GO:0010718(positive regulation of epithelial to mesenchymal transition);GO:0010909(positive regulation of heparan sulfate proteoglycan biosynthetic process);GO:0014704(intercalated disc);GO:0016020(membrane);GO:0016032(viral process);GO:0016055(Wnt signaling pathway);GO:0016323(basolateral plasma membrane);GO:0016328(lateral plasma membrane);GO:0016331(morphogenesis of embryonic epithelium);GO:0016342(catenin complex);GO:0016525(negative regulation of angiogenesis);GO:0016600(flotillin complex);GO:0019827(stem cell population maintenance);GO:0019899(enzyme binding);GO:0019900(kinase binding);GO:0019901(protein kinase binding);GO:0019903(protein phosphatase binding);GO:0021819(layer formation in cerebral cortex);GO:0022009(central nervous system vasculogenesis);GO:0022405(hair cycle process);GO:0030018(Z disc);GO:0030027(lamellipodium);GO:0030054(cell junction);GO:0030097(hemopoiesis);GO:0030154(cell differentiation);GO:0030182(neuron differentiation);GO:0030217(T cell differentiation);GO:0030316(osteoclast differentiation);GO:0030324(lung development);GO:0030331(estrogen receptor binding);GO:0030521(androgen receptor signaling pathway);GO:0030539(male genitalia development);GO:0030856(regulation of epithelial cell differentiation);GO:0030857(negative regulation of epithelial cell differentiation);GO:0030858(positive regulation of epithelial cell differentiation);GO:0030877(beta-catenin destruction complex);GO:0030900(forebrain development);GO:0030901(midbrain development);GO:0030902(hindbrain development);GO:0030997(regulation of centriole-centriole cohesion);GO:0031016(pancreas development);GO:0031069(hair follicle morphogenesis);GO:0031253(cell projection membrane);GO:0031528(microvillus membrane);GO:0031641(regulation of myelination);GO:0032212(positive regulation of telomere maintenance via telomerase);GO:0032331(negative regulation of chondrocyte differentiation);GO:0032355(response to estradiol);GO:0032481(positive regulation of type I interferon production);GO:0032991(protein-containing complex);GO:0032993(protein-DNA complex);GO:0033077(T cell differentiation in thymus);GO:0033234(negative regulation of protein sumoylation);GO:0034332(adherens junction organization);GO:0034333(adherens junction assembly);GO:0034394(protein localization to cell surface);GO:0034613(cellular protein localization);GO:0034750(Scrib-APC-beta-catenin complex);GO:0035050(embryonic heart tube development);GO:0035112(genitalia morphogenesis);GO:0035115(embryonic forelimb morphogenesis);GO:0035116(embryonic hindlimb morphogenesis);GO:0035257(nuclear hormone receptor binding);GO:0035315(hair cell differentiation);GO:0035635(entry of bacterium into host cell);GO:0036023(embryonic skeletal limb joint morphogenesis);GO:0042127(regulation of cell population proliferation);GO:0042129(regulation of T cell proliferation);GO:0042475(odontogenesis of dentin-containing tooth);GO:0042493(response to drug);GO:0042733(embryonic digit morphogenesis);GO:0042734(presynaptic membrane);GO:0042981(regulation of apoptotic process);GO:0042995(cell projection);GO:0043065(positive regulation of apoptotic process);GO:0043066(negative regulation of apoptotic process);GO:0043123(positive regulation of I-kappaB kinase/NF-kappaB signaling);GO:0043161(proteasome-mediated ubiquitin-dependent protein catabolic process);GO:0043296(apical junction complex);GO:0043410(positive regulation of MAPK cascade);GO:0043525(positive regulation of neuron apoptotic process);GO:0043588(skin development);GO:0044093(positive regulation of molecular function);GO:0044325(ion channel binding);GO:0044334(canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition);GO:0044336(canonical Wnt signaling pathway involved in negative regulation of apoptotic process);GO:0044798(nuclear transcription factor complex);GO:0045177(apical part of cell);GO:0045202(synapse);GO:0045211(postsynaptic membrane);GO:0045294(alpha-catenin binding);GO:0045296(cadherin binding);GO:0045453(bone resorption);GO:0045595(regulation of cell differentiation);GO:0045596(negative regulation of cell differentiation);GO:0045603(positive regulation of endothelial cell differentiation);GO:0045667(regulation of osteoblast differentiation);GO:0045669(positive regulation of osteoblast differentiation);GO:0045670(regulation of osteoclast differentiation);GO:0045671(negative regulation of osteoclast differentiation);GO:0045743(positive regulation of fibroblast growth factor receptor signaling pathway);GO:0045765(regulation of angiogenesis);GO:0045892(negative regulation of transcription, DNA-templated);GO:0045893(positive regulation of transcription, DNA-templated);GO:0045944(positive regulation of transcription by RNA polymerase II);GO:0045976(negative regulation of mitotic cell cycle, embryonic);GO:0046332(SMAD binding);GO:0046982(protein heterodimerization activity);GO:0048096(chromatin-mediated maintenance of transcription);GO:0048145(regulation of fibroblast proliferation);GO:0048469(cell maturation);GO:0048471(perinuclear region of cytoplasm);GO:0048489(synaptic vesicle transport);GO:0048513(animal organ development);GO:0048538(thymus development);GO:0048599(oocyte development);GO:0048617(embryonic foregut morphogenesis);GO:0048643(positive regulation of skeletal muscle tissue development);GO:0048660(regulation of smooth muscle cell proliferation);GO:0048715(negative regulation of oligodendrocyte differentiation);GO:0050679(positive regulation of epithelial cell proliferation);GO:0050681(androgen receptor binding);GO:0050767(regulation of neurogenesis);GO:0050768(negative regulation of neurogenesis);GO:0050808(synapse organization);GO:0051091(positive regulation of DNA-binding transcription factor activity);GO:0051145(smooth muscle cell differentiation);GO:0051149(positive regulation of muscle cell differentiation);GO:0051571(positive regulation of histone H3-K4 methylation);GO:0051884(regulation of timing of anagen);GO:0051973(positive regulation of telomerase activity);GO:0060066(oviduct development);GO:0060070(canonical Wnt signaling pathway);GO:0060173(limb development);GO:0060439(trachea morphogenesis);GO:0060440(trachea formation);GO:0060441(epithelial tube branching involved in lung morphogenesis);GO:0060479(lung cell differentiation);GO:0060484(lung-associated mesenchyme development);GO:0060492(lung induction);GO:0060742(epithelial cell differentiation involved in prostate gland development);GO:0060769(positive regulation of epithelial cell proliferation involved in prostate gland development);GO:0060789(hair follicle placode formation);GO:0060828(regulation of canonical Wnt signaling pathway);GO:0060916(mesenchymal cell proliferation involved in lung development);GO:0061047(positive regulation of branching involved in lung morphogenesis);GO:0061154(endothelial tube morphogenesis);GO:0061198(fungiform papilla formation);GO:0061324(canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation);GO:0061549(sympathetic ganglion development);GO:0061550(cranial ganglion development);GO:0070062(extracellular exosome);GO:0070369(beta-catenin-TCF7L2 complex);GO:0070411(I-SMAD binding);GO:0070491(repressing transcription factor binding);GO:0070602(regulation of centromeric sister chromatid cohesion);GO:0071363(cellular response to growth factor stimulus);GO:0071681(cellular response to indole-3-methanol);GO:0071944(cell periphery);GO:0072033(renal vesicle formation);GO:0072053(renal inner medulla development);GO:0072054(renal outer medulla development);GO:0072079(nephron tubule formation);GO:0072182(regulation of nephron tubule epithelial cell differentiation);GO:0090279(regulation of calcium ion import);GO:0097091(synaptic vesicle clustering);GO:0097718(disordered domain specific binding);GO:0098609(cell-cell adhesion);GO:0098685(Schaffer collateral - CA1 synapse);GO:0098831(presynaptic active zone cytoplasmic component);GO:0099092(postsynaptic density, intracellular component);GO:1901215(negative regulation of neuron death);GO:1903204(negative regulation of oxidative stress-induced neuron death);GO:1904501(positive regulation of chromatin-mediated maintenance of transcription);GO:1904793(regulation of euchromatin binding);GO:1904796(regulation of core promoter binding);GO:1904798(positive regulation of core promoter binding);GO:1904837(beta-catenin-TCF complex assembly);GO:1904886(beta-catenin destruction complex disassembly);GO:1904888(cranial skeletal system development);GO:1904948(midbrain dopaminergic neuron differentiation);GO:1904954(canonical Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation);GO:1990138(neuron projection extension);GO:1990403(embryonic brain development);GO:1990791(dorsal root ganglion development);GO:1990907(beta-catenin-TCF complex);GO:1990909(Wnt signalosome);GO:2000008(regulation of protein localization to cell surface);GO:2000017(positive regulation of determination of dorsal identity);GO:2000144(positive regulation of DNA-templated transcription, initiation);GO:2000179(positive regulation of neural precursor cell proliferation);GO:2001234(negative regulation of apoptotic signaling pathway)","04015(Rap1 signaling pathway);04310(Wnt signaling pathway);04390(Hippo signaling pathway);04510(Focal adhesion);04520(Adherens junction);04550(Signaling pathways regulating pluripotency of stem cells);04670(Leukocyte transendothelial migration);04916(Melanogenesis);04919(Thyroid hormone signaling pathway);04934(Cushing syndrome);05100(Bacterial invasion of epithelial cells);05130(Pathogenic Escherichia coli infection);05160(Hepatitis C);05163(Human cytomegalovirus infection);05165(Human papillomavirus infection);05167(Kaposi sarcoma-associated herpesvirus infection);05200(Pathways in cancer);05205(Proteoglycans in cancer);05210(Colorectal cancer);05213(Endometrial cancer);05215(Prostate cancer);05216(Thyroid cancer);05217(Basal cell carcinoma);05224(Breast cancer);05225(Hepatocellular carcinoma);05226(Gastric cancer);05412(Arrhythmogenic right ventricular cardiomyopathy (ARVC));05418(Fluid shear stress and atherosclerosis)","NA","NA","catenin beta 1 [Source:HGNC Symbol;Acc:HGNC:2514]",{"v":0.499761,"d":"0.50"},{"v":0.693931,"d":"0.69"},{"v":0.973178,"d":"0.97"},{"v":5.012733,"d":"5.01"},{"v":7.918247,"d":"7.92"},{"v":0.507572,"d":"0.51"},{"v":0.161242818422699,"d":"0.16"},{"v":-2.63269318896657,"d":"-2.63"},{"v":0.0114159803162819,"d":"0.01"},{"v":0.444525793023065,"d":"0.44"},"down","yes"]
[163757,0,"chr5","+",141417645,141420429,"ENST00000612073",1,2785,"ENSG00000254122","PCDHGB7","GO:0005509(calcium ion binding);GO:0005886(plasma membrane);GO:0005887(integral component of plasma membrane);GO:0007155(cell adhesion);GO:0007156(homophilic cell adhesion via plasma membrane adhesion molecules);GO:0016020(membrane);GO:0016021(integral component of membrane)","NA","K16496","NA","protocadherin gamma subfamily B, 7 [Source:HGNC Symbol;Acc:HGNC:8714]",{"v":16.638004,"d":"16.64"},{"v":0.012308,"d":"0.01"},{"v":0.10418,"d":"0.10"},{"v":0.009299,"d":"0.01"},{"v":0.123799,"d":"0.12"},{"v":0.413407,"d":"0.41"},{"v":30.6575273785235,"d":"30.66"},{"v":4.93816943889669,"d":"4.94"},{"v":0.011636031656398,"d":"0.01"},{"v":0.45260923991107,"d":"0.45"},"up","yes"]
[89524,0,"chr17","-",68867289,68955392,"ENST00000586539",40,6002,"ENSG00000141338","ABCA8","GO:0000166(nucleotide binding);GO:0005319(lipid transporter activity);GO:0005524(ATP binding);GO:0005886(plasma membrane);GO:0006869(lipid transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016887(ATPase activity);GO:0042626(ATPase activity, coupled to transmembrane movement of substances);GO:0043231(intracellular membrane-bounded organelle);GO:0055085(transmembrane transport)","02010(ABC transporters)","K05650","NA","ATP binding cassette subfamily A member 8 [Source:HGNC Symbol;Acc:HGNC:38]",{"v":0.702052,"d":"0.70"},{"v":0.588175,"d":"0.59"},{"v":0.500709,"d":"0.50"},{"v":2.880837,"d":"2.88"},{"v":2.412303,"d":"2.41"},{"v":2.864832,"d":"2.86"},{"v":0.219532011141985,"d":"0.22"},{"v":-2.18749677267304,"d":"-2.19"},{"v":0.0116992384115924,"d":"0.01"},{"v":0.454433406730514,"d":"0.45"},"down","yes"]
[330,0,"chr1","-",1311585,1324687,"ENST00000545578",18,2263,"ENSG00000127054","INTS11","GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0016180(snRNA processing);GO:0016787(hydrolase activity);GO:0032039(integrator complex);GO:0042795(snRNA transcription by RNA polymerase II);GO:0072562(blood microparticle)","NA","K13148","EC:3.1.27.-","integrator complex subunit 11 [Source:HGNC Symbol;Acc:HGNC:26052]",{"v":0.263914,"d":"0.26"},{"v":0.928934,"d":"0.93"},{"v":0.599257,"d":"0.60"},0,{"v":0.072015,"d":"0.07"},0,{"v":24.8851628133028,"d":"24.89"},{"v":4.63721392088868,"d":"4.64"},{"v":0.011707945739052,"d":"0.01"},{"v":0.454433406730514,"d":"0.45"},"up","yes"]
[50299,0,"chr13","+",19959859,20003092,"ENST00000620447",5,1069,"ENSG00000121741","ZMYM2","GO:0000981(DNA-binding transcription factor activity, RNA polymerase II-specific);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005829(cytosol);GO:0006357(regulation of transcription by RNA polymerase II);GO:0008150(biological_process);GO:0008270(zinc ion binding);GO:0016605(PML body);GO:0022604(regulation of cell morphogenesis);GO:0031624(ubiquitin conjugating enzyme binding);GO:0046872(metal ion binding)","NA","NA","NA","zinc finger MYM-type containing 2 [Source:HGNC Symbol;Acc:HGNC:12989]",{"v":2.109179,"d":"2.11"},{"v":0.1744,"d":"0.17"},{"v":1.156908,"d":"1.16"},{"v":0.106139,"d":"0.11"},0,0,{"v":32.4149181733387,"d":"32.41"},{"v":5.01858602594052,"d":"5.02"},{"v":0.0117809782006797,"d":"0.01"},{"v":0.456780083277155,"d":"0.46"},"up","yes"]
[12175,0,"chr1","-",155659446,155688774,"ENST00000359205",10,2690,"ENSG00000163374","YY1AP1","GO:0001650(fibrillar center);GO:0003714(transcription corepressor activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005730(nucleolus);GO:0005737(cytoplasm);GO:0008283(cell population proliferation);GO:0030154(cell differentiation);GO:0030183(B cell differentiation);GO:0031011(Ino80 complex);GO:0045892(negative regulation of transcription, DNA-templated);GO:0051726(regulation of cell cycle)","NA","NA","NA","YY1 associated protein 1 [Source:HGNC Symbol;Acc:HGNC:30935]",{"v":6.392429,"d":"6.39"},{"v":0.542679,"d":"0.54"},{"v":2.900432,"d":"2.90"},{"v":0.449113,"d":"0.45"},{"v":0.008767,"d":"0.01"},0,{"v":21.4806062723858,"d":"21.48"},{"v":4.42496280766231,"d":"4.42"},{"v":0.0118028802250243,"d":"0.01"},{"v":0.457141405730419,"d":"0.46"},"up","yes"]
[22978,0,"chr10","-",90740823,90857698,"ENST00000371719",3,3033,"ENSG00000148680","HTR7","GO:0004930(G protein-coupled receptor activity);GO:0004993(G protein-coupled serotonin receptor activity);GO:0005515(protein binding);GO:0005886(plasma membrane);GO:0005887(integral component of plasma membrane);GO:0006939(smooth muscle contraction);GO:0007165(signal transduction);GO:0007186(G protein-coupled receptor signaling pathway);GO:0007187(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger);GO:0007268(chemical synaptic transmission);GO:0007623(circadian rhythm);GO:0008015(blood circulation);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0030425(dendrite);GO:0030594(neurotransmitter receptor activity);GO:0042310(vasoconstriction);GO:0098664(G protein-coupled serotonin receptor signaling pathway)","04014(Ras signaling pathway);04020(Calcium signaling pathway);04080(Neuroactive ligand-receptor interaction);04726(Serotonergic synapse)","K04163","NA","5-hydroxytryptamine receptor 7 [Source:HGNC Symbol;Acc:HGNC:5302]",{"v":0.528099,"d":"0.53"},{"v":0.637872,"d":"0.64"},{"v":0.944096,"d":"0.94"},{"v":0.107016,"d":"0.11"},0,0,{"v":19.7173039545488,"d":"19.72"},{"v":4.30139039318987,"d":"4.30"},{"v":0.0118342042161034,"d":"0.01"},{"v":0.457866495389817,"d":"0.46"},"up","yes"]
[128070,0,"chr20","-",57648392,57710569,"ENST00000395816",4,4519,"ENSG00000124225","PMEPA1","GO:0000139(Golgi membrane);GO:0005515(protein binding);GO:0005768(endosome);GO:0005794(Golgi apparatus);GO:0005886(plasma membrane);GO:0009968(negative regulation of signal transduction);GO:0010008(endosome membrane);GO:0010991(negative regulation of SMAD protein complex assembly);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0030512(negative regulation of transforming growth factor beta receptor signaling pathway);GO:0030521(androgen receptor signaling pathway);GO:0031901(early endosome membrane);GO:0043231(intracellular membrane-bounded organelle);GO:0050699(WW domain binding);GO:0060394(negative regulation of pathway-restricted SMAD protein phosphorylation);GO:0070412(R-SMAD binding)","NA","NA","NA","prostate transmembrane protein, androgen induced 1 [Source:HGNC Symbol;Acc:HGNC:14107]",0,{"v":0.565529,"d":"0.57"},{"v":0.874344,"d":"0.87"},{"v":0.015396,"d":"0.02"},0,{"v":0.028927,"d":"0.03"},{"v":32.4859102497575,"d":"32.49"},{"v":5.02174222471115,"d":"5.02"},{"v":0.0119862708306471,"d":"0.01"},{"v":0.463256616252564,"d":"0.46"},"up","yes"]
[152436,0,"chr4","-",77720230,77819615,"ENST00000512485",12,1890,"ENSG00000138767","CNOT6L","GO:0000288(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay);GO:0000289(nuclear-transcribed mRNA poly(A) tail shortening);GO:0004518(nuclease activity);GO:0004527(exonuclease activity);GO:0004535(poly(A)-specific ribonuclease activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0006397(mRNA processing);GO:0006417(regulation of translation);GO:0006977(DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest);GO:0008284(positive regulation of cell population proliferation);GO:0010606(positive regulation of cytoplasmic mRNA processing body assembly);GO:0016787(hydrolase activity);GO:0030014(CCR4-NOT complex);GO:0031047(gene silencing by RNA);GO:0046872(metal ion binding);GO:0061157(mRNA destabilization);GO:0090305(nucleic acid phosphodiester bond hydrolysis);GO:0090503(RNA phosphodiester bond hydrolysis, exonucleolytic)","03018(RNA degradation)","K12603","EC:3.1.13.4","CCR4-NOT transcription complex subunit 6 like [Source:HGNC Symbol;Acc:HGNC:18042]",{"v":0.141976,"d":"0.14"},{"v":0.182412,"d":"0.18"},{"v":0.171507,"d":"0.17"},{"v":0.066367,"d":"0.07"},{"v":2.4378,"d":"2.44"},{"v":2.281089,"d":"2.28"},{"v":0.103629774457208,"d":"0.10"},{"v":-3.27048952342391,"d":"-3.27"},{"v":0.0120277147323266,"d":"0.01"},{"v":0.464364374309697,"d":"0.46"},"down","yes"]
[4327,0,"chr1","-",36095241,36100249,"ENST00000303143",2,4447,"ENSG00000171812","COL8A2","GO:0001525(angiogenesis);GO:0005201(extracellular matrix structural constituent);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0005581(collagen trimer);GO:0005604(basement membrane);GO:0005615(extracellular space);GO:0005788(endoplasmic reticulum lumen);GO:0007155(cell adhesion);GO:0030020(extracellular matrix structural constituent conferring tensile strength);GO:0030198(extracellular matrix organization);GO:0030674(protein binding, bridging);GO:0031012(extracellular matrix);GO:0048593(camera-type eye morphogenesis);GO:0050673(epithelial cell proliferation);GO:0062023(collagen-containing extracellular matrix);GO:0098609(cell-cell adhesion)","NA","NA","NA","collagen type VIII alpha 2 chain [Source:HGNC Symbol;Acc:HGNC:2216]",{"v":1.76798,"d":"1.77"},{"v":1.232682,"d":"1.23"},{"v":1.19773,"d":"1.20"},{"v":4.990572,"d":"4.99"},{"v":6.162395,"d":"6.16"},{"v":5.493834,"d":"5.49"},{"v":0.252204132193327,"d":"0.25"},{"v":-1.98733618144969,"d":"-1.99"},{"v":0.012214559097105,"d":"0.01"},{"v":0.470705679613243,"d":"0.47"},"down","yes"]
[43368,0,"chr12","-",53210567,53232256,"ENST00000394426",9,2640,"ENSG00000172819","RARG","GO:0000122(negative regulation of transcription by RNA polymerase II);GO:0000790(nuclear chromatin);GO:0000976(transcription regulatory region sequence-specific DNA binding);GO:0000977(RNA polymerase II regulatory region sequence-specific DNA binding);GO:0000981(DNA-binding transcription factor activity, RNA polymerase II-specific);GO:0001843(neural tube closure);GO:0002063(chondrocyte development);GO:0002068(glandular epithelial cell development);GO:0003417(growth plate cartilage development);GO:0003430(growth plate cartilage chondrocyte growth);GO:0003677(DNA binding);GO:0003700(DNA-binding transcription factor activity);GO:0003707(steroid hormone receptor activity);GO:0004879(nuclear receptor activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005667(transcription factor complex);GO:0006355(regulation of transcription, DNA-templated);GO:0006367(transcription initiation from RNA polymerase II promoter);GO:0007275(multicellular organism development);GO:0008134(transcription factor binding);GO:0008270(zinc ion binding);GO:0008284(positive regulation of cell population proliferation);GO:0008285(negative regulation of cell population proliferation);GO:0008361(regulation of cell size);GO:0009755(hormone-mediated signaling pathway);GO:0009952(anterior/posterior pattern specification);GO:0010468(regulation of gene expression);GO:0010628(positive regulation of gene expression);GO:0016021(integral component of membrane);GO:0030154(cell differentiation);GO:0030374(nuclear receptor transcription coactivator activity);GO:0031076(embryonic camera-type eye development);GO:0031641(regulation of myelination);GO:0032331(negative regulation of chondrocyte differentiation);GO:0032526(response to retinoic acid);GO:0033993(response to lipid);GO:0035116(embryonic hindlimb morphogenesis);GO:0035264(multicellular organism growth);GO:0038023(signaling receptor activity);GO:0043065(positive regulation of apoptotic process);GO:0043068(positive regulation of programmed cell death);GO:0043401(steroid hormone mediated signaling pathway);GO:0043565(sequence-specific DNA binding);GO:0045596(negative regulation of cell differentiation);GO:0045637(regulation of myeloid cell differentiation);GO:0045944(positive regulation of transcription by RNA polymerase II);GO:0046872(metal ion binding);GO:0046965(retinoid X receptor binding);GO:0048048(embryonic eye morphogenesis);GO:0048384(retinoic acid receptor signaling pathway);GO:0048608(reproductive structure development);GO:0048732(gland development);GO:0060070(canonical Wnt signaling pathway);GO:0060173(limb development);GO:0060324(face development);GO:0060348(bone development);GO:0060349(bone morphogenesis);GO:0060429(epithelium development);GO:0060534(trachea cartilage development);GO:0060740(prostate gland epithelium morphogenesis);GO:0061037(negative regulation of cartilage development);GO:0070384(Harderian gland development);GO:0071300(cellular response to retinoic acid);GO:0090575(RNA polymerase II transcription factor complex);GO:1990830(cellular response to leukemia inhibitory factor)","NA","K08529","NA","retinoic acid receptor gamma [Source:HGNC Symbol;Acc:HGNC:9866]",{"v":17.688169,"d":"17.69"},{"v":0.351316,"d":"0.35"},{"v":0.07171,"d":"0.07"},{"v":0.146594,"d":"0.15"},{"v":0.240547,"d":"0.24"},{"v":0.742544,"d":"0.74"},{"v":16.0320753130297,"d":"16.03"},{"v":4.002889285821,"d":"4.00"},{"v":0.0122178765723999,"d":"0.01"},{"v":0.470705679613243,"d":"0.47"},"up","yes"]
[67180,0,"chr15","+",78872814,78898133,"ENST00000331268",13,2359,"ENSG00000185787","MORF4L1","GO:0000123(histone acetyltransferase complex);GO:0000724(double-strand break repair via homologous recombination);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0006281(DNA repair);GO:0006310(DNA recombination);GO:0006325(chromatin organization);GO:0006342(chromatin silencing);GO:0006355(regulation of transcription, DNA-templated);GO:0006974(cellular response to DNA damage stimulus);GO:0016573(histone acetylation);GO:0016575(histone deacetylation);GO:0016580(Sin3 complex);GO:0016607(nuclear speck);GO:0035267(NuA4 histone acetyltransferase complex);GO:0040008(regulation of growth);GO:0043967(histone H4 acetylation);GO:0043968(histone H2A acetylation);GO:0047485(protein N-terminus binding)","NA","K11339","NA","mortality factor 4 like 1 [Source:HGNC Symbol;Acc:HGNC:16989]",{"v":2.198247,"d":"2.20"},{"v":54.385082,"d":"54.39"},{"v":3.221575,"d":"3.22"},{"v":3.176637,"d":"3.18"},{"v":2.719849,"d":"2.72"},{"v":2.896934,"d":"2.90"},{"v":6.80109718403079,"d":"6.80"},{"v":2.76576750728545,"d":"2.77"},{"v":0.0122609510224945,"d":"0.01"},{"v":0.471864778227993,"d":"0.47"},"up","yes"]
[73212,0,"chr16","+",28823093,28837237,"ENST00000336783",22,4367,"ENSG00000168488","ATXN2L","GO:0003723(RNA binding);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0010494(cytoplasmic stress granule);GO:0010603(regulation of cytoplasmic mRNA processing body assembly);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016607(nuclear speck);GO:0034063(stress granule assembly);GO:0045296(cadherin binding)","NA","NA","NA","ataxin 2 like [Source:HGNC Symbol;Acc:HGNC:31326]",{"v":0.398645,"d":"0.40"},{"v":0.261942,"d":"0.26"},{"v":0.367453,"d":"0.37"},{"v":0.443059,"d":"0.44"},{"v":9.118078,"d":"9.12"},{"v":0.277846,"d":"0.28"},{"v":0.104486408808715,"d":"0.10"},{"v":-3.25861280061445,"d":"-3.26"},{"v":0.0123008964902275,"d":"0.01"},{"v":0.472901131735414,"d":"0.47"},"down","yes"]
[150050,0,"chr4","-",15605006,15655341,"ENST00000511441",12,2951,"ENSG00000118564","FBXL5","GO:0000151(ubiquitin ligase complex);GO:0000209(protein polyubiquitination);GO:0004842(ubiquitin-protein transferase activity);GO:0005506(iron ion binding);GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0006511(ubiquitin-dependent protein catabolic process);GO:0006879(cellular iron ion homeostasis);GO:0016567(protein ubiquitination);GO:0019005(SCF ubiquitin ligase complex);GO:0031146(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process);GO:0043687(post-translational protein modification);GO:0046872(metal ion binding);GO:0048471(perinuclear region of cytoplasm);GO:0055072(iron ion homeostasis);GO:1903364(positive regulation of cellular protein catabolic process)","NA","K10271","NA","F-box and leucine rich repeat protein 5 [Source:HGNC Symbol;Acc:HGNC:13602]",0,{"v":0.292674,"d":"0.29"},0,{"v":0.392808,"d":"0.39"},{"v":5.344616,"d":"5.34"},{"v":2.297133,"d":"2.30"},{"v":0.0364268994544441,"d":"0.04"},{"v":-4.77885198722936,"d":"-4.78"},{"v":0.0123252003260989,"d":"0.01"},{"v":0.473111122370533,"d":"0.47"},"down","yes"]
[10071,0,"chr1","+",119711940,119734682,"ENST00000462324",7,767,"ENSG00000092621","PHGDH","GO:0004617(phosphoglycerate dehydrogenase activity);GO:0005829(cytosol);GO:0006520(cellular amino acid metabolic process);GO:0006541(glutamine metabolic process);GO:0006544(glycine metabolic process);GO:0006563(L-serine metabolic process);GO:0006564(L-serine biosynthetic process);GO:0006566(threonine metabolic process);GO:0007420(brain development);GO:0008652(cellular amino acid biosynthetic process);GO:0009055(electron transfer activity);GO:0009448(gamma-aminobutyric acid metabolic process);GO:0010468(regulation of gene expression);GO:0016491(oxidoreductase activity);GO:0016616(oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor);GO:0019530(taurine metabolic process);GO:0021510(spinal cord development);GO:0021782(glial cell development);GO:0021915(neural tube development);GO:0022008(neurogenesis);GO:0022900(electron transport chain);GO:0030060(L-malate dehydrogenase activity);GO:0031175(neuron projection development);GO:0051287(NAD binding);GO:0055114(oxidation-reduction process);GO:0070062(extracellular exosome);GO:0070314(G1 to G0 transition)","00260(Glycine, serine and threonine metabolism)","K00058","1.1.1.399;EC:1.1.1.95","phosphoglycerate dehydrogenase [Source:HGNC Symbol;Acc:HGNC:8923]",0,{"v":2.261595,"d":"2.26"},{"v":2.423228,"d":"2.42"},{"v":0.062066,"d":"0.06"},0,0,{"v":75.4813102181549,"d":"75.48"},{"v":6.238047560603,"d":"6.24"},{"v":0.0123324038779217,"d":"0.01"},{"v":0.473111122370533,"d":"0.47"},"up","yes"]
[199087,0,"chr9","-",125437394,125672643,"ENST00000373498",11,3131,"ENSG00000119487","MAPKAP1","GO:0005515(protein binding);GO:0005546(phosphatidylinositol-4,5-bisphosphate binding);GO:0005547(phosphatidylinositol-3,4,5-trisphosphate binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0005794(Golgi apparatus);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0016020(membrane);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0017016(Ras GTPase binding);GO:0019901(protein kinase binding);GO:0021762(substantia nigra development);GO:0030950(establishment or maintenance of actin cytoskeleton polarity);GO:0031410(cytoplasmic vesicle);GO:0031932(TORC2 complex);GO:0032148(activation of protein kinase B activity);GO:0033138(positive regulation of peptidyl-serine phosphorylation);GO:0038203(TORC2 signaling);GO:0043325(phosphatidylinositol-3,4-bisphosphate binding);GO:0046580(negative regulation of Ras protein signal transduction);GO:0070300(phosphatidic acid binding);GO:0080025(phosphatidylinositol-3,5-bisphosphate binding);GO:1900407(regulation of cellular response to oxidative stress)","04150(mTOR signaling pathway)","K20410","NA","mitogen-activated protein kinase associated protein 1 [Source:HGNC Symbol;Acc:HGNC:18752]",{"v":2.633831,"d":"2.63"},{"v":0.150298,"d":"0.15"},{"v":2.358703,"d":"2.36"},{"v":11.493332,"d":"11.49"},{"v":15.786324,"d":"15.79"},{"v":3.377934,"d":"3.38"},{"v":0.167750694036942,"d":"0.17"},{"v":-2.5756093595702,"d":"-2.58"},{"v":0.01247167297256,"d":"0.01"},{"v":0.477743410253494,"d":"0.48"},"down","yes"]
[49457,0,"chr12","+",123633739,123662603,"ENST00000618160",12,3252,"ENSG00000111358","GTF2H3","GO:0000438(core TFIIH complex portion of holo TFIIH complex);GO:0000439(transcription factor TFIIH core complex);GO:0000717(nucleotide-excision repair, DNA duplex unwinding);GO:0004672(protein kinase activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005669(transcription factor TFIID complex);GO:0005675(transcription factor TFIIH holo complex);GO:0006281(DNA repair);GO:0006283(transcription-coupled nucleotide-excision repair);GO:0006289(nucleotide-excision repair);GO:0006293(nucleotide-excision repair, preincision complex stabilization);GO:0006294(nucleotide-excision repair, preincision complex assembly);GO:0006295(nucleotide-excision repair, DNA incision, 3'-to lesion);GO:0006296(nucleotide-excision repair, DNA incision, 5'-to lesion);GO:0006355(regulation of transcription, DNA-templated);GO:0006361(transcription initiation from RNA polymerase I promoter);GO:0006362(transcription elongation from RNA polymerase I promoter);GO:0006363(termination of RNA polymerase I transcription);GO:0006366(transcription by RNA polymerase II);GO:0006367(transcription initiation from RNA polymerase II promoter);GO:0006368(transcription elongation from RNA polymerase II promoter);GO:0006370(7-methylguanosine mRNA capping);GO:0006974(cellular response to DNA damage stimulus);GO:0008094(DNA-dependent ATPase activity);GO:0008353(RNA polymerase II CTD heptapeptide repeat kinase activity);GO:0016251(RNA polymerase II general transcription initiation factor activity);GO:0033683(nucleotide-excision repair, DNA incision);GO:0046872(metal ion binding);GO:0047485(protein N-terminus binding);GO:0070816(phosphorylation of RNA polymerase II C-terminal domain);GO:0070911(global genome nucleotide-excision repair);GO:0097550(transcriptional preinitiation complex)","03022(Basal transcription factors);03420(Nucleotide excision repair);05203(Viral carcinogenesis)","K03143","NA","general transcription factor IIH subunit 3 [Source:HGNC Symbol;Acc:HGNC:4657]",{"v":0.271837,"d":"0.27"},{"v":0.008116,"d":"0.01"},{"v":0.004111,"d":"0.00"},{"v":4.080295,"d":"4.08"},{"v":0.001732,"d":"0.00"},{"v":3.235505,"d":"3.24"},{"v":0.0388196457494139,"d":"0.04"},{"v":-4.68706923704761,"d":"-4.69"},{"v":0.0124794521423222,"d":"0.01"},{"v":0.477743410253494,"d":"0.48"},"down","yes"]
[105059,0,"chr19","+",44871853,44878938,"ENST00000591581",4,950,"ENSG00000130202","NECTIN2","GO:0001618(virus receptor activity);GO:0001675(acrosome assembly);GO:0002860(positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target);GO:0002891(positive regulation of immunoglobulin mediated immune response);GO:0005515(protein binding);GO:0005886(plasma membrane);GO:0005911(cell-cell junction);GO:0005915(zonula adherens);GO:0005925(focal adhesion);GO:0007010(cytoskeleton organization);GO:0007155(cell adhesion);GO:0007156(homophilic cell adhesion via plasma membrane adhesion molecules);GO:0007286(spermatid development);GO:0007289(spermatid nucleus differentiation);GO:0009566(fertilization);GO:0009986(cell surface);GO:0015026(coreceptor activity);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016032(viral process);GO:0019062(virion attachment to host cell);GO:0019064(fusion of virus membrane with host plasma membrane);GO:0030382(sperm mitochondrion organization);GO:0032990(cell part morphogenesis);GO:0033005(positive regulation of mast cell activation);GO:0034332(adherens junction organization);GO:0042271(susceptibility to natural killer cell mediated cytotoxicity);GO:0042802(identical protein binding);GO:0042803(protein homodimerization activity);GO:0043296(apical junction complex);GO:0044291(cell-cell contact zone);GO:0044406(adhesion of symbiont to host);GO:0044782(cilium organization);GO:0045954(positive regulation of natural killer cell mediated cytotoxicity);GO:0046596(regulation of viral entry into host cell);GO:0046814(coreceptor-mediated virion attachment to host cell);GO:0050776(regulation of immune response);GO:0050839(cell adhesion molecule binding);GO:0050862(positive regulation of T cell receptor signaling pathway);GO:0051654(establishment of mitochondrion localization);GO:0060370(susceptibility to T cell mediated cytotoxicity);GO:0070062(extracellular exosome)","04514(Cell adhesion molecules (CAMs));04520(Adherens junction)","NA","NA","nectin cell adhesion molecule 2 [Source:HGNC Symbol;Acc:HGNC:9707]",{"v":3.051873,"d":"3.05"},{"v":3.050768,"d":"3.05"},{"v":2.244641,"d":"2.24"},{"v":0.494919,"d":"0.49"},{"v":0.328926,"d":"0.33"},{"v":0.522309,"d":"0.52"},{"v":6.20083734847573,"d":"6.20"},{"v":2.63246304726149,"d":"2.63"},{"v":0.0125092287375562,"d":"0.01"},{"v":0.477980355889399,"d":"0.48"},"up","yes"]
[189659,0,"chr8","-",63027000,63038801,"ENST00000518966",4,574,"ENSG00000137563","GGH","GO:0005576(extracellular region);GO:0005615(extracellular space);GO:0005634(nucleus);GO:0005764(lysosome);GO:0005773(vacuole);GO:0005829(cytosol);GO:0006508(proteolysis);GO:0008238(exopeptidase activity);GO:0008242(omega peptidase activity);GO:0010043(response to zinc ion);GO:0016787(hydrolase activity);GO:0032868(response to insulin);GO:0034722(gamma-glutamyl-peptidase activity);GO:0035578(azurophil granule lumen);GO:0035580(specific granule lumen);GO:0042470(melanosome);GO:0042493(response to drug);GO:0043312(neutrophil degranulation);GO:0045471(response to ethanol);GO:0046900(tetrahydrofolylpolyglutamate metabolic process);GO:0070062(extracellular exosome);GO:1904724(tertiary granule lumen)","00790(Folate biosynthesis);01523(Antifolate resistance)","K01307","EC:3.4.19.9","gamma-glutamyl hydrolase [Source:HGNC Symbol;Acc:HGNC:4248]",{"v":0.145543,"d":"0.15"},{"v":0.153834,"d":"0.15"},{"v":0.130884,"d":"0.13"},{"v":2.739614,"d":"2.74"},{"v":2.317232,"d":"2.32"},{"v":0.326762,"d":"0.33"},{"v":0.0799205662819433,"d":"0.08"},{"v":-3.64528938430634,"d":"-3.65"},{"v":0.0125119548156019,"d":"0.01"},{"v":0.477980355889399,"d":"0.48"},"down","yes"]
[81731,0,"chr17","-",15229818,15262541,"ENST00000395936",6,1795,"ENSG00000109099","PMP22","GO:0005515(protein binding);GO:0005886(plasma membrane);GO:0005923(bicellular tight junction);GO:0007268(chemical synaptic transmission);GO:0007422(peripheral nervous system development);GO:0008219(cell death);GO:0008285(negative regulation of cell population proliferation);GO:0010977(negative regulation of neuron projection development);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0030154(cell differentiation);GO:0032060(bleb assembly);GO:0032288(myelin assembly);GO:0042552(myelination);GO:0043218(compact myelin)","NA","K19289","NA","peripheral myelin protein 22 [Source:HGNC Symbol;Acc:HGNC:9118]",{"v":22.351555,"d":"22.35"},{"v":12.827038,"d":"12.83"},0,0,0,{"v":0.470817,"d":"0.47"},{"v":74.718187745982,"d":"74.72"},{"v":6.22338755847895,"d":"6.22"},{"v":0.0125340523587317,"d":"0.01"},{"v":0.47832155692513,"d":"0.48"},"up","yes"]
[94202,0,"chr18","-",36798018,36828781,"ENST00000589049",6,1102,"ENSG00000134779","TPGS2","GO:0005737(cytoplasm);GO:0005856(cytoskeleton);GO:0005874(microtubule);GO:0018095(protein polyglutamylation)","NA","K16605","NA","tubulin polyglutamylase complex subunit 2 [Source:HGNC Symbol;Acc:HGNC:24561]",{"v":0.581141,"d":"0.58"},{"v":10.14986,"d":"10.15"},{"v":8.849966,"d":"8.85"},{"v":0.639256,"d":"0.64"},{"v":0.874556,"d":"0.87"},{"v":0.9198,"d":"0.92"},{"v":8.04605130152218,"d":"8.05"},{"v":3.00828093659835,"d":"3.01"},{"v":0.0125844252402424,"d":"0.01"},{"v":0.479739946461706,"d":"0.48"},"up","yes"]
[10325,0,"chr1","+",145644086,145670460,"ENST00000493684",7,2699,"ENSG00000117262","GPR89A","GO:0000139(Golgi membrane);GO:0005244(voltage-gated ion channel activity);GO:0005794(Golgi apparatus);GO:0006811(ion transport);GO:0008308(voltage-gated anion channel activity);GO:0015031(protein transport);GO:0015698(inorganic anion transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0030660(Golgi-associated vesicle membrane);GO:0032580(Golgi cisterna membrane);GO:0034220(ion transmembrane transport);GO:0034765(regulation of ion transmembrane transport);GO:0043123(positive regulation of I-kappaB kinase/NF-kappaB signaling);GO:0051452(intracellular pH reduction)","NA","K22193","NA","G protein-coupled receptor 89A [Source:HGNC Symbol;Acc:HGNC:31984]",{"v":0.765009,"d":"0.77"},{"v":1.539352,"d":"1.54"},{"v":1.199118,"d":"1.20"},{"v":4.7094,"d":"4.71"},{"v":6.561628,"d":"6.56"},{"v":5.260517,"d":"5.26"},{"v":0.211926894915146,"d":"0.21"},{"v":-2.23836140808082,"d":"-2.24"},{"v":0.0126212192098662,"d":"0.01"},{"v":0.480571318906637,"d":"0.48"},"down","yes"]
[86615,0,"chr17","-",45263135,45273966,"ENST00000592267",8,3152,"ENSG00000006062","MAP3K14","GO:0000165(MAPK cascade);GO:0000166(nucleotide binding);GO:0000186(activation of MAPKK activity);GO:0001650(fibrillar center);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0004704(NF-kappaB-inducing kinase activity);GO:0004709(MAP kinase kinase kinase activity);GO:0005515(protein binding);GO:0005524(ATP binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0006468(protein phosphorylation);GO:0006955(immune response);GO:0007249(I-kappaB kinase/NF-kappaB signaling);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0016740(transferase activity);GO:0023014(signal transduction by protein phosphorylation);GO:0031098(stress-activated protein kinase signaling cascade);GO:0032147(activation of protein kinase activity);GO:0033209(tumor necrosis factor-mediated signaling pathway);GO:0038061(NIK/NF-kappaB signaling);GO:0043123(positive regulation of I-kappaB kinase/NF-kappaB signaling);GO:0043231(intracellular membrane-bounded organelle);GO:0051607(defense response to virus);GO:0071260(cellular response to mechanical stimulus)","04010(MAPK signaling pathway);04064(NF-kappa B signaling pathway);04210(Apoptosis);04380(Osteoclast differentiation);04625(C-type lectin receptor signaling pathway);04660(T cell receptor signaling pathway);04668(TNF signaling pathway);04672(Intestinal immune network for IgA production);05120(Epithelial cell signaling in Helicobacter pylori infection);05166(Human T-cell leukemia virus 1 infection);05169(Epstein-Barr virus infection)","NA","NA","mitogen-activated protein kinase kinase kinase 14 [Source:HGNC Symbol;Acc:HGNC:6853]",{"v":0.042363,"d":"0.04"},0,{"v":0.028389,"d":"0.03"},{"v":0.753623,"d":"0.75"},{"v":1.243756,"d":"1.24"},0,{"v":0.035422421082829,"d":"0.04"},{"v":-4.81919336772383,"d":"-4.82"},{"v":0.0126326895005736,"d":"0.01"},{"v":0.480571318906637,"d":"0.48"},"down","yes"]
[144626,0,"chr3","-",136337388,136752378,"ENST00000483235",36,5206,"ENSG00000118007","STAG1","GO:0000775(chromosome, centromeric region);GO:0000785(chromatin);GO:0001228(DNA-binding transcription activator activity, RNA polymerase II-specific);GO:0003682(chromatin binding);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005694(chromosome);GO:0005829(cytosol);GO:0007049(cell cycle);GO:0007059(chromosome segregation);GO:0007062(sister chromatid cohesion);GO:0008278(cohesin complex);GO:0016363(nuclear matrix);GO:0016604(nuclear body);GO:0045944(positive regulation of transcription by RNA polymerase II);GO:0051301(cell division);GO:0097431(mitotic spindle pole);GO:1901673(regulation of mitotic spindle assembly)","04110(Cell cycle)","K06671","NA","stromal antigen 1 [Source:HGNC Symbol;Acc:HGNC:11354]",{"v":0.056334,"d":"0.06"},{"v":0.011373,"d":"0.01"},0,{"v":1.25039,"d":"1.25"},0,{"v":1.02926,"d":"1.03"},{"v":0.0297006119360428,"d":"0.03"},{"v":-5.07336353390022,"d":"-5.07"},{"v":0.0126718215683174,"d":"0.01"},{"v":0.481258694046488,"d":"0.48"},"down","yes"]
[46154,0,"chr12","-",81258266,81759330,"ENST00000549396",33,5363,"ENSG00000139220","PPFIA2","GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0007160(cell-matrix adhesion);GO:0007269(neurotransmitter secretion);GO:0009986(cell surface);GO:0014047(glutamate secretion);GO:0045202(synapse);GO:0048786(presynaptic active zone);GO:0070062(extracellular exosome);GO:0099172(presynapse organization)","NA","NA","NA","PTPRF interacting protein alpha 2 [Source:HGNC Symbol;Acc:HGNC:9246]",{"v":6.402972,"d":"6.40"},{"v":6.637724,"d":"6.64"},{"v":0.592385,"d":"0.59"},{"v":0.548906,"d":"0.55"},{"v":0.843733,"d":"0.84"},{"v":1.061087,"d":"1.06"},{"v":5.55607309047546,"d":"5.56"},{"v":2.47406557818412,"d":"2.47"},{"v":0.0126772521387968,"d":"0.01"},{"v":0.481258694046488,"d":"0.48"},"up","yes"]
[76058,0,"chr16","-",66802880,66830976,"ENST00000379463",21,1909,"ENSG00000159593","NAE1","GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0006915(apoptotic process);GO:0007049(cell cycle);GO:0007165(signal transduction);GO:0008641(ubiquitin-like modifier activating enzyme activity);GO:0016020(membrane);GO:0019781(NEDD8 activating enzyme activity);GO:0031625(ubiquitin protein ligase binding);GO:0032446(protein modification by small protein conjugation);GO:0032991(protein-containing complex);GO:0033314(mitotic DNA replication checkpoint);GO:0042981(regulation of apoptotic process);GO:0043523(regulation of neuron apoptotic process);GO:0043687(post-translational protein modification);GO:0045116(protein neddylation);GO:0046982(protein heterodimerization activity);GO:0051402(neuron apoptotic process)","05010(Alzheimer disease)","K04532","NA","NEDD8 activating enzyme E1 subunit 1 [Source:HGNC Symbol;Acc:HGNC:621]",{"v":1.937669,"d":"1.94"},0,{"v":0.818647,"d":"0.82"},{"v":11.531259,"d":"11.53"},{"v":13.676442,"d":"13.68"},{"v":6.252959,"d":"6.25"},{"v":0.0876115122823234,"d":"0.09"},{"v":-3.5127357352295,"d":"-3.51"},{"v":0.0127192060158269,"d":"0.01"},{"v":0.482347342959281,"d":"0.48"},"down","yes"]
[31230,0,"chr11","-",61964585,61967607,"ENST00000526640",4,786,"ENSG00000167996","FTH1","GO:0004322(ferroxidase activity);GO:0005506(iron ion binding);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0005623(cell);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0006826(iron ion transport);GO:0006879(cellular iron ion homeostasis);GO:0006880(intracellular sequestering of iron ion);GO:0006955(immune response);GO:0008043(intracellular ferritin complex);GO:0008198(ferrous iron binding);GO:0008199(ferric iron binding);GO:0008285(negative regulation of cell population proliferation);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016491(oxidoreductase activity);GO:0042802(identical protein binding);GO:0043312(neutrophil degranulation);GO:0044754(autolysosome);GO:0046872(metal ion binding);GO:0048147(negative regulation of fibroblast proliferation);GO:0055114(oxidation-reduction process);GO:0060547(negative regulation of necrotic cell death);GO:0070062(extracellular exosome);GO:1904724(tertiary granule lumen);GO:1904813(ficolin-1-rich granule lumen)","04216(Ferroptosis);04217(Necroptosis);04978(Mineral absorption)","K00522","EC:1.16.3.2","ferritin heavy chain 1 [Source:HGNC Symbol;Acc:HGNC:3976]",{"v":825.889648,"d":"825.89"},{"v":8.251794,"d":"8.25"},{"v":724.998291,"d":"725.00"},{"v":81.954987,"d":"81.95"},{"v":55.476135,"d":"55.48"},{"v":105.369484,"d":"105.37"},{"v":6.42148204934876,"d":"6.42"},{"v":2.68290630334285,"d":"2.68"},{"v":0.0127689574522591,"d":"0.01"},{"v":0.483390681049817,"d":"0.48"},"up","yes"]
[207462,0,"chrX","-",154487306,154490614,"ENST00000369649",4,1763,"ENSG00000126903","SLC10A3","GO:0010033(response to organic substance);GO:0015293(symporter activity);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0032526(response to retinoic acid);GO:0055085(transmembrane transport)","NA","K14343","NA","solute carrier family 10 member 3 [Source:HGNC Symbol;Acc:HGNC:22979]",{"v":1.054514,"d":"1.05"},{"v":2.770374,"d":"2.77"},{"v":1.793758,"d":"1.79"},{"v":0.500916,"d":"0.50"},{"v":0.156223,"d":"0.16"},{"v":0.109149,"d":"0.11"},{"v":7.33229020942518,"d":"7.33"},{"v":2.87426388836181,"d":"2.87"},{"v":0.0127733293093263,"d":"0.01"},{"v":0.483390681049817,"d":"0.48"},"up","yes"]
[91874,0,"chr17","-",81932384,81937328,"ENST00000629768",7,1740,"ENSG00000183010","PYCR1","GO:0004735(pyrroline-5-carboxylate reductase activity);GO:0005515(protein binding);GO:0005739(mitochondrion);GO:0005759(mitochondrial matrix);GO:0006561(proline biosynthetic process);GO:0008652(cellular amino acid biosynthetic process);GO:0016491(oxidoreductase activity);GO:0034599(cellular response to oxidative stress);GO:0042802(identical protein binding);GO:0051881(regulation of mitochondrial membrane potential);GO:0055114(oxidation-reduction process);GO:0055129(L-proline biosynthetic process);GO:1903206(negative regulation of hydrogen peroxide-induced cell death)","00330(Arginine and proline metabolism)","K00286","EC:1.5.1.2","pyrroline-5-carboxylate reductase 1 [Source:HGNC Symbol;Acc:HGNC:9721]",{"v":0.909331,"d":"0.91"},{"v":0.801516,"d":"0.80"},{"v":0.590011,"d":"0.59"},{"v":4.180387,"d":"4.18"},{"v":8.915798,"d":"8.92"},{"v":1.379552,"d":"1.38"},{"v":0.158945827766835,"d":"0.16"},{"v":-2.65339294779868,"d":"-2.65"},{"v":0.0128999327614396,"d":"0.01"},{"v":0.487673836860669,"d":"0.49"},"down","yes"]
[102921,0,"chr19","+",36215133,36238774,"ENST00000443387",4,3326,"ENSG00000167635","ZNF146","GO:0000981(DNA-binding transcription factor activity, RNA polymerase II-specific);GO:0003676(nucleic acid binding);GO:0003677(DNA binding);GO:0005634(nucleus);GO:0005730(nucleolus);GO:0005829(cytosol);GO:0006355(regulation of transcription, DNA-templated);GO:0006357(regulation of transcription by RNA polymerase II);GO:0008201(heparin binding);GO:0008270(zinc ion binding);GO:0046872(metal ion binding)","NA","NA","NA","zinc finger protein 146 [Source:HGNC Symbol;Acc:HGNC:12931]",{"v":19.954435,"d":"19.95"},{"v":1.685329,"d":"1.69"},{"v":19.479452,"d":"19.48"},{"v":1.897732,"d":"1.90"},{"v":2.960869,"d":"2.96"},{"v":3.548977,"d":"3.55"},{"v":4.89073262240326,"d":"4.89"},{"v":2.29005059432669,"d":"2.29"},{"v":0.0129568142268483,"d":"0.01"},{"v":0.489315032080457,"d":"0.49"},"up","yes"]
[145294,0,"chr3","+",148991558,149027631,"ENST00000484197",6,1563,"ENSG00000163754","GYG1","GO:0005515(protein binding);GO:0005576(extracellular region);GO:0005829(cytosol);GO:0005978(glycogen biosynthetic process);GO:0008466(glycogenin glucosyltransferase activity);GO:0016020(membrane);GO:0016740(transferase activity);GO:0016757(transferase activity, transferring glycosyl groups);GO:0030145(manganese ion binding);GO:0034774(secretory granule lumen);GO:0042803(protein homodimerization activity);GO:0043202(lysosomal lumen);GO:0043312(neutrophil degranulation);GO:0046872(metal ion binding);GO:0102751(UDP-alpha-D-glucose:glucosyl-glycogenin alpha-D-glucosyltransferase activity);GO:1904813(ficolin-1-rich granule lumen)","00500(Starch and sucrose metabolism)","NA","NA","glycogenin 1 [Source:HGNC Symbol;Acc:HGNC:4699]",{"v":0.324422,"d":"0.32"},{"v":1.859898,"d":"1.86"},{"v":5.226155,"d":"5.23"},{"v":0.111621,"d":"0.11"},{"v":0.481832,"d":"0.48"},{"v":0.209264,"d":"0.21"},{"v":9.23174045149162,"d":"9.23"},{"v":3.20660266347542,"d":"3.21"},{"v":0.0129731008640685,"d":"0.01"},{"v":0.489421344124205,"d":"0.49"},"up","yes"]
[78357,0,"chr16","+",84819985,84909508,"ENST00000262424",15,4583,"ENSG00000103196","CRISPLD2","GO:0005539(glycosaminoglycan binding);GO:0005576(extracellular region);GO:0005615(extracellular space);GO:0008201(heparin binding);GO:0030133(transport vesicle);GO:0030198(extracellular matrix organization);GO:0030324(lung development);GO:0031012(extracellular matrix);GO:0034774(secretory granule lumen);GO:0043312(neutrophil degranulation);GO:0060325(face morphogenesis);GO:0070062(extracellular exosome);GO:1904813(ficolin-1-rich granule lumen)","NA","NA","NA","cysteine rich secretory protein LCCL domain containing 2 [Source:HGNC Symbol;Acc:HGNC:25248]",{"v":16.101162,"d":"16.10"},{"v":15.377212,"d":"15.38"},{"v":17.766586,"d":"17.77"},{"v":4.724987,"d":"4.72"},{"v":5.154136,"d":"5.15"},{"v":5.480222,"d":"5.48"},{"v":3.20618880557732,"d":"3.21"},{"v":1.68085938520854,"d":"1.68"},{"v":0.0129897615628527,"d":"0.01"},{"v":0.489541532757717,"d":"0.49"},"up","yes"]
[18619,0,"chr10","+",1049538,1132297,"ENST00000358220",14,4582,"ENSG00000047056","WDR37","GO:0005515(protein binding);GO:0030687(preribosome, large subunit precursor);GO:0070545(PeBoW complex)","NA","NA","NA","WD repeat domain 37 [Source:HGNC Symbol;Acc:HGNC:31406]",{"v":0.042113,"d":"0.04"},{"v":0.735381,"d":"0.74"},{"v":0.33877,"d":"0.34"},{"v":0.040239,"d":"0.04"},0,0,{"v":27.740848430627,"d":"27.74"},{"v":4.79394000684376,"d":"4.79"},{"v":0.0130562694004397,"d":"0.01"},{"v":0.491538100847643,"d":"0.49"},"up","yes"]
[198185,0,"chr9","+",107284053,107332192,"ENST00000416373",10,3835,"ENSG00000119318","RAD23B","GO:0000502(proteasome complex);GO:0000715(nucleotide-excision repair, DNA damage recognition);GO:0000717(nucleotide-excision repair, DNA duplex unwinding);GO:0003684(damaged DNA binding);GO:0003697(single-stranded DNA binding);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0006281(DNA repair);GO:0006289(nucleotide-excision repair);GO:0006294(nucleotide-excision repair, preincision complex assembly);GO:0006457(protein folding);GO:0006974(cellular response to DNA damage stimulus);GO:0007283(spermatogenesis);GO:0016579(protein deubiquitination);GO:0031593(polyubiquitin modification-dependent protein binding);GO:0032434(regulation of proteasomal ubiquitin-dependent protein catabolic process);GO:0043130(ubiquitin binding);GO:0043161(proteasome-mediated ubiquitin-dependent protein catabolic process);GO:0048568(embryonic organ development);GO:0070628(proteasome binding);GO:0070911(global genome nucleotide-excision repair);GO:0071942(XPC complex);GO:0098761(cellular response to interleukin-7)","03420(Nucleotide excision repair);04141(Protein processing in endoplasmic reticulum)","K10839","NA","RAD23 homolog B, nucleotide excision repair protein [Source:HGNC Symbol;Acc:HGNC:9813]",0,{"v":36.178886,"d":"36.18"},{"v":0.005498,"d":"0.01"},{"v":0.000384,"d":"0.00"},0,{"v":0.253547,"d":"0.25"},{"v":142.496914516148,"d":"142.50"},{"v":7.15478687073319,"d":"7.15"},{"v":0.0130752914516736,"d":"0.01"},{"v":0.491744656769464,"d":"0.49"},"up","yes"]
[22168,0,"chr10","+",74826600,75032624,"ENST00000287239",18,8314,"ENSG00000156650","KAT6B","GO:0000123(histone acetyltransferase complex);GO:0000786(nucleosome);GO:0000790(nuclear chromatin);GO:0003677(DNA binding);GO:0004402(histone acetyltransferase activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005694(chromosome);GO:0006325(chromatin organization);GO:0006334(nucleosome assembly);GO:0006355(regulation of transcription, DNA-templated);GO:0008134(transcription factor binding);GO:0010485(H4 histone acetyltransferase activity);GO:0016407(acetyltransferase activity);GO:0016573(histone acetylation);GO:0016740(transferase activity);GO:0016746(transferase activity, transferring acyl groups);GO:0042393(histone binding);GO:0043966(histone H3 acetylation);GO:0043967(histone H4 acetylation);GO:0045892(negative regulation of transcription, DNA-templated);GO:0045893(positive regulation of transcription, DNA-templated);GO:0045944(positive regulation of transcription by RNA polymerase II);GO:0046872(metal ion binding);GO:0070776(MOZ/MORF histone acetyltransferase complex);GO:1990830(cellular response to leukemia inhibitory factor)","NA","K11306","EC:2.3.1.48","lysine acetyltransferase 6B [Source:HGNC Symbol;Acc:HGNC:17582]",{"v":0.452853,"d":"0.45"},{"v":0.594467,"d":"0.59"},{"v":0.853715,"d":"0.85"},0,{"v":0.084783,"d":"0.08"},0,{"v":22.4223606147459,"d":"22.42"},{"v":4.48686626722823,"d":"4.49"},{"v":0.0131153308150868,"d":"0.01"},{"v":0.492740401770532,"d":"0.49"},"up","yes"]
[87530,0,"chr17","+",50056110,50090481,"ENST00000320031",26,4889,"ENSG00000005884","ITGA3","GO:0001764(neuron migration);GO:0001968(fibronectin binding);GO:0002020(protease binding);GO:0005178(integrin binding);GO:0005515(protein binding);GO:0005518(collagen binding);GO:0005886(plasma membrane);GO:0005925(focal adhesion);GO:0007155(cell adhesion);GO:0007160(cell-matrix adhesion);GO:0007229(integrin-mediated signaling pathway);GO:0007507(heart development);GO:0007613(memory);GO:0008305(integrin complex);GO:0009897(external side of plasma membrane);GO:0009986(cell surface);GO:0010628(positive regulation of gene expression);GO:0010634(positive regulation of epithelial cell migration);GO:0010811(positive regulation of cell-substrate adhesion);GO:0010976(positive regulation of neuron projection development);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016323(basolateral plasma membrane);GO:0017015(regulation of transforming growth factor beta receptor signaling pathway);GO:0019904(protein domain specific binding);GO:0030054(cell junction);GO:0030111(regulation of Wnt signaling pathway);GO:0030198(extracellular matrix organization);GO:0030324(lung development);GO:0030426(growth cone);GO:0030510(regulation of BMP signaling pathway);GO:0031345(negative regulation of cell projection organization);GO:0031527(filopodium membrane);GO:0034667(integrin alpha3-beta1 complex);GO:0034698(response to gonadotropin);GO:0035024(negative regulation of Rho protein signal transduction);GO:0035640(exploration behavior);GO:0042493(response to drug);GO:0042995(cell projection);GO:0043235(receptor complex);GO:0043236(laminin binding);GO:0043588(skin development);GO:0045202(synapse);GO:0046872(metal ion binding);GO:0046982(protein heterodimerization activity);GO:0048333(mesodermal cell differentiation);GO:0048471(perinuclear region of cytoplasm);GO:0050900(leukocyte migration);GO:0060076(excitatory synapse);GO:0060135(maternal process involved in female pregnancy);GO:0070062(extracellular exosome);GO:0071438(invadopodium membrane);GO:0071944(cell periphery);GO:0072006(nephron development);GO:0097060(synaptic membrane);GO:0097062(dendritic spine maintenance);GO:0097205(renal filtration);GO:1903078(positive regulation of protein localization to plasma membrane);GO:1990812(growth cone filopodium)","04151(PI3K-Akt signaling pathway);04510(Focal adhesion);04512(ECM-receptor interaction);04640(Hematopoietic cell lineage);04810(Regulation of actin cytoskeleton);05165(Human papillomavirus infection);05200(Pathways in cancer);05222(Small cell lung cancer);05410(Hypertrophic cardiomyopathy (HCM));05412(Arrhythmogenic right ventricular cardiomyopathy (ARVC));05414(Dilated cardiomyopathy (DCM))","K06482","NA","integrin subunit alpha 3 [Source:HGNC Symbol;Acc:HGNC:6139]",{"v":1.198357,"d":"1.20"},{"v":1.296883,"d":"1.30"},{"v":1.457984,"d":"1.46"},{"v":5.904795,"d":"5.90"},{"v":5.087584,"d":"5.09"},{"v":4.220435,"d":"4.22"},{"v":0.259861456269695,"d":"0.26"},{"v":-1.94418543172859,"d":"-1.94"},{"v":0.0131811591784421,"d":"0.01"},{"v":0.494316110762323,"d":"0.49"},"down","yes"]
[68202,0,"chr15","+",90388247,90500854,"ENST00000633485",39,5863,"ENSG00000140575","IQGAP1","GO:0001726(ruffle);GO:0001817(regulation of cytokine production);GO:0005095(GTPase inhibitor activity);GO:0005096(GTPase activator activity);GO:0005509(calcium ion binding);GO:0005515(protein binding);GO:0005516(calmodulin binding);GO:0005547(phosphatidylinositol-3,4,5-trisphosphate binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005874(microtubule);GO:0005884(actin filament);GO:0005886(plasma membrane);GO:0005911(cell-cell junction);GO:0005925(focal adhesion);GO:0007165(signal transduction);GO:0007173(epidermal growth factor receptor signaling pathway);GO:0007346(regulation of mitotic cell cycle);GO:0008543(fibroblast growth factor receptor signaling pathway);GO:0015629(actin cytoskeleton);GO:0015630(microtubule cytoskeleton);GO:0016020(membrane);GO:0016032(viral process);GO:0016328(lateral plasma membrane);GO:0016477(cell migration);GO:0017048(Rho GTPase binding);GO:0019901(protein kinase binding);GO:0019903(protein phosphatase binding);GO:0019904(protein domain specific binding);GO:0030424(axon);GO:0030426(growth cone);GO:0030496(midbody);GO:0030667(secretory granule membrane);GO:0031234(extrinsic component of cytoplasmic side of plasma membrane);GO:0031252(cell leading edge);GO:0031267(small GTPase binding);GO:0032947(protein-containing complex scaffold activity);GO:0032991(protein-containing complex);GO:0034260(negative regulation of GTPase activity);GO:0035305(negative regulation of dephosphorylation);GO:0036057(slit diaphragm);GO:0036120(cellular response to platelet-derived growth factor stimulus);GO:0036464(cytoplasmic ribonucleoprotein granule);GO:0043005(neuron projection);GO:0043087(regulation of GTPase activity);GO:0043312(neutrophil degranulation);GO:0043406(positive regulation of MAP kinase activity);GO:0043539(protein serine/threonine kinase activator activity);GO:0043547(positive regulation of GTPase activity);GO:0044344(cellular response to fibroblast growth factor stimulus);GO:0044548(S100 protein binding);GO:0044877(protein-containing complex binding);GO:0045121(membrane raft);GO:0045296(cadherin binding);GO:0045860(positive regulation of protein kinase activity);GO:0048008(platelet-derived growth factor receptor signaling pathway);GO:0048365(Rac GTPase binding);GO:0051019(mitogen-activated protein kinase binding);GO:0051894(positive regulation of focal adhesion assembly);GO:0070062(extracellular exosome);GO:0071277(cellular response to calcium ion);GO:0071364(cellular response to epidermal growth factor stimulus);GO:0072015(glomerular visceral epithelial cell development);GO:1900006(positive regulation of dendrite development);GO:1900086(positive regulation of peptidyl-tyrosine autophosphorylation);GO:1903829(positive regulation of cellular protein localization);GO:1904754(positive regulation of vascular associated smooth muscle cell migration);GO:1990138(neuron projection extension);GO:1990776(response to angiotensin);GO:1990904(ribonucleoprotein complex)","04520(Adherens junction);04810(Regulation of actin cytoskeleton);05205(Proteoglycans in cancer)","K16848","NA","IQ motif containing GTPase activating protein 1 [Source:HGNC Symbol;Acc:HGNC:6110]",0,0,{"v":0.178036,"d":"0.18"},{"v":0.001986,"d":"0.00"},{"v":26.313629,"d":"26.31"},{"v":0.001287,"d":"0.00"},{"v":0.00676508199939339,"d":"0.01"},{"v":-7.207676863483,"d":"-7.21"},{"v":0.0131844842094327,"d":"0.01"},{"v":0.494316110762323,"d":"0.49"},"down","yes"]
[168010,0,"chr6","+",26365159,26378320,"ENST00000508906",10,3733,"ENSG00000186470","BTN3A2","GO:0002250(adaptive immune response);GO:0002376(immune system process);GO:0002456(T cell mediated immunity);GO:0005102(signaling receptor binding);GO:0005886(plasma membrane);GO:0009897(external side of plasma membrane);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0050776(regulation of immune response);GO:0050852(T cell receptor signaling pathway);GO:0072643(interferon-gamma secretion)","NA","K06712","NA","butyrophilin subfamily 3 member A2 [Source:HGNC Symbol;Acc:HGNC:1139]",{"v":0.306537,"d":"0.31"},{"v":0.291791,"d":"0.29"},{"v":3.826542,"d":"3.83"},{"v":0.120175,"d":"0.12"},{"v":0.184943,"d":"0.18"},{"v":0.164635,"d":"0.16"},{"v":9.41956730451961,"d":"9.42"},{"v":3.2356607899908,"d":"3.24"},{"v":0.0132649069681016,"d":"0.01"},{"v":0.496818629021784,"d":"0.50"},"up","yes"]
[2987,0,"chr1","+",25800176,25818219,"ENST00000354177",13,4227,"ENSG00000162430","SELENON","GO:0005509(calcium ion binding);GO:0005515(protein binding);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0016020(membrane);GO:0016491(oxidoreductase activity);GO:0048741(skeletal muscle fiber development);GO:0055074(calcium ion homeostasis);GO:0055114(oxidation-reduction process);GO:0060314(regulation of ryanodine-sensitive calcium-release channel activity);GO:1902884(positive regulation of response to oxidative stress)","NA","K19874","NA","selenoprotein N [Source:HGNC Symbol;Acc:HGNC:15999]",{"v":0.836969,"d":"0.84"},0,{"v":0.760944,"d":"0.76"},{"v":0.033294,"d":"0.03"},0,0,{"v":47.9940229470776,"d":"47.99"},{"v":5.58478284235584,"d":"5.58"},{"v":0.0133974135984203,"d":"0.01"},{"v":0.501205741085285,"d":"0.50"},"up","yes"]
[67379,0,"chr15","+",81196879,81314058,"ENST00000394660",19,9616,"ENSG00000172349","IL16","GO:0005125(cytokine activity);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0005615(extracellular space);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0006935(chemotaxis);GO:0006955(immune response);GO:0010469(regulation of signaling receptor activity);GO:0016032(viral process);GO:0016607(nuclear speck);GO:0019221(cytokine-mediated signaling pathway);GO:0030595(leukocyte chemotaxis);GO:0042609(CD4 receptor binding);GO:0050930(induction of positive chemotaxis);GO:0051924(regulation of calcium ion transport)","04060(Cytokine-cytokine receptor interaction)","K22628","NA","interleukin 16 [Source:HGNC Symbol;Acc:HGNC:5980]",{"v":0.044298,"d":"0.04"},{"v":0.097501,"d":"0.10"},{"v":0.025165,"d":"0.03"},{"v":1.294144,"d":"1.29"},{"v":0.161832,"d":"0.16"},{"v":0.089036,"d":"0.09"},{"v":0.108066474564599,"d":"0.11"},{"v":-3.21000906932691,"d":"-3.21"},{"v":0.0134187442984956,"d":"0.01"},{"v":0.501205741085285,"d":"0.50"},"down","yes"]
[151321,0,"chr4","+",52712781,52714137,"ENST00000425653",2,823,"ENSG00000226950","DANCR","NA","NA","NA","NA","differentiation antagonizing non-protein coding RNA [Source:HGNC Symbol;Acc:HGNC:28964]",{"v":0.595163,"d":"0.60"},{"v":1.157274,"d":"1.16"},{"v":0.545337,"d":"0.55"},{"v":9.985398,"d":"9.99"},{"v":1.858588,"d":"1.86"},{"v":4.076832,"d":"4.08"},{"v":0.144325121988079,"d":"0.14"},{"v":-2.79260565013046,"d":"-2.79"},{"v":0.0134342918865207,"d":"0.01"},{"v":0.501205741085285,"d":"0.50"},"down","yes"]
[2702,0,"chr1","-",23429627,23484184,"ENST00000492982",25,3024,"ENSG00000088280","ASAP3","GO:0001726(ruffle);GO:0005096(GTPase activator activity);GO:0005515(protein binding);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005925(focal adhesion);GO:0016477(cell migration);GO:0043231(intracellular membrane-bounded organelle);GO:0043547(positive regulation of GTPase activity);GO:0046872(metal ion binding);GO:0051492(regulation of stress fiber assembly)","04144(Endocytosis);04666(Fc gamma R-mediated phagocytosis)","K12488","NA","ArfGAP with SH3 domain, ankyrin repeat and PH domain 3 [Source:HGNC Symbol;Acc:HGNC:14987]",{"v":0.432661,"d":"0.43"},{"v":4.429467,"d":"4.43"},{"v":0.430626,"d":"0.43"},{"v":0.27165,"d":"0.27"},{"v":0.211151,"d":"0.21"},{"v":0.09613,"d":"0.10"},{"v":9.14228811378212,"d":"9.14"},{"v":3.19255528533606,"d":"3.19"},{"v":0.0134469419327597,"d":"0.01"},{"v":0.501205741085285,"d":"0.50"},"up","yes"]
[15302,0,"chr1","+",201982955,202006147,"ENST00000471105",10,2093,"ENSG00000176393","RNPEP","GO:0004177(aminopeptidase activity);GO:0004301(epoxide hydrolase activity);GO:0005576(extracellular region);GO:0005615(extracellular space);GO:0005886(plasma membrane);GO:0006508(proteolysis);GO:0008233(peptidase activity);GO:0008235(metalloexopeptidase activity);GO:0008237(metallopeptidase activity);GO:0008270(zinc ion binding);GO:0016787(hydrolase activity);GO:0030141(secretory granule);GO:0045776(negative regulation of blood pressure);GO:0046872(metal ion binding);GO:0070062(extracellular exosome)","NA","K01260","EC:3.4.11.6","arginyl aminopeptidase [Source:HGNC Symbol;Acc:HGNC:10078]",{"v":0.001314,"d":"0.00"},{"v":0.547798,"d":"0.55"},{"v":0.028479,"d":"0.03"},{"v":10.375147,"d":"10.38"},{"v":0.074942,"d":"0.07"},{"v":1.335457,"d":"1.34"},{"v":0.0490084209929688,"d":"0.05"},{"v":-4.35082652460859,"d":"-4.35"},{"v":0.0134510211273921,"d":"0.01"},{"v":0.501205741085285,"d":"0.50"},"down","yes"]
[133139,0,"chr22","-",27851669,27919268,"ENST00000335272",12,2926,"ENSG00000180957","PITPNB","GO:0000139(Golgi membrane);GO:0005548(phospholipid transporter activity);GO:0005622(intracellular);GO:0005737(cytoplasm);GO:0005789(endoplasmic reticulum membrane);GO:0005794(Golgi apparatus);GO:0006629(lipid metabolic process);GO:0006890(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum);GO:0006997(nucleus organization);GO:0008289(lipid binding);GO:0008525(phosphatidylcholine transporter activity);GO:0008526(phosphatidylinositol transporter activity);GO:0015914(phospholipid transport);GO:0031210(phosphatidylcholine binding);GO:0035091(phosphatidylinositol binding)","NA","NA","NA","phosphatidylinositol transfer protein beta [Source:HGNC Symbol;Acc:HGNC:9002]",{"v":12.019946,"d":"12.02"},0,{"v":3.64477,"d":"3.64"},0,0,{"v":0.217167,"d":"0.22"},{"v":72.1321195209217,"d":"72.13"},{"v":6.17256991128834,"d":"6.17"},{"v":0.0134902995967105,"d":"0.01"},{"v":0.502154287242307,"d":"0.50"},"up","yes"]
[48082,0,"chr12","+",111686076,111757094,"ENST00000455480",22,4071,"ENSG00000111271","ACAD10","GO:0003995(acyl-CoA dehydrogenase activity);GO:0005739(mitochondrion);GO:0005759(mitochondrial matrix);GO:0006635(fatty acid beta-oxidation);GO:0016491(oxidoreductase activity);GO:0016627(oxidoreductase activity, acting on the CH-CH group of donors);GO:0016787(hydrolase activity);GO:0050660(flavin adenine dinucleotide binding);GO:0055114(oxidation-reduction process)","NA","K11729","NA","acyl-CoA dehydrogenase family member 10 [Source:HGNC Symbol;Acc:HGNC:21597]",{"v":2.10263,"d":"2.10"},{"v":3.39389,"d":"3.39"},{"v":0.326682,"d":"0.33"},{"v":0.296026,"d":"0.30"},{"v":0.12173,"d":"0.12"},{"v":0.37243,"d":"0.37"},{"v":7.36940669665117,"d":"7.37"},{"v":2.88154847410267,"d":"2.88"},{"v":0.0135528565616207,"d":"0.01"},{"v":0.503966508581044,"d":"0.50"},"up","yes"]
[75049,0,"chr16","+",55480533,55505525,"ENST00000543485",13,1978,"ENSG00000087245","MMP2","GO:0001525(angiogenesis);GO:0001666(response to hypoxia);GO:0001955(blood vessel maturation);GO:0001957(intramembranous ossification);GO:0004222(metalloendopeptidase activity);GO:0004252(serine-type endopeptidase activity);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0005615(extracellular space);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005739(mitochondrion);GO:0005886(plasma membrane);GO:0006508(proteolysis);GO:0007566(embryo implantation);GO:0008233(peptidase activity);GO:0008237(metallopeptidase activity);GO:0008270(zinc ion binding);GO:0016020(membrane);GO:0016787(hydrolase activity);GO:0019221(cytokine-mediated signaling pathway);GO:0022617(extracellular matrix disassembly);GO:0030017(sarcomere);GO:0030198(extracellular matrix organization);GO:0030574(collagen catabolic process);GO:0031012(extracellular matrix);GO:0034614(cellular response to reactive oxygen species);GO:0035987(endodermal cell differentiation);GO:0044267(cellular protein metabolic process);GO:0046872(metal ion binding);GO:0048013(ephrin receptor signaling pathway);GO:0048661(positive regulation of smooth muscle cell proliferation);GO:0048705(skeletal system morphogenesis);GO:0048771(tissue remodeling);GO:0060325(face morphogenesis);GO:0060346(bone trabecula formation);GO:0062023(collagen-containing extracellular matrix);GO:0071230(cellular response to amino acid stimulus);GO:1904645(response to amyloid-beta);GO:1904707(positive regulation of vascular smooth muscle cell proliferation)","01522(Endocrine resistance);04670(Leukocyte transendothelial migration);04912(GnRH signaling pathway);04915(Estrogen signaling pathway);04926(Relaxin signaling pathway);04933(AGE-RAGE signaling pathway in diabetic complications);05200(Pathways in cancer);05205(Proteoglycans in cancer);05219(Bladder cancer);05418(Fluid shear stress and atherosclerosis)","K01398","EC:3.4.24.24","matrix metallopeptidase 2 [Source:HGNC Symbol;Acc:HGNC:7166]",0,{"v":151.518356,"d":"151.52"},{"v":0.016723,"d":"0.02"},{"v":1.149834,"d":"1.15"},{"v":0.006045,"d":"0.01"},{"v":0.005167,"d":"0.01"},{"v":130.515999366089,"d":"130.52"},{"v":7.02808286087091,"d":"7.03"},{"v":0.0135804389335498,"d":"0.01"},{"v":0.504475814372049,"d":"0.50"},"up","yes"]
[19420,0,"chr10","-",15075475,15088776,"ENST00000356189",4,3370,"ENSG00000176244","ACBD7","GO:0000062(fatty-acyl-CoA binding);GO:0008289(lipid binding)","NA","NA","NA","acyl-CoA binding domain containing 7 [Source:HGNC Symbol;Acc:HGNC:17715]",{"v":0.022667,"d":"0.02"},{"v":0.051494,"d":"0.05"},{"v":0.058619,"d":"0.06"},{"v":0.295308,"d":"0.30"},{"v":0.401327,"d":"0.40"},{"v":0.445269,"d":"0.45"},{"v":0.116279477083888,"d":"0.12"},{"v":-3.1043316061762,"d":"-3.10"},{"v":0.013607471949764,"d":"0.01"},{"v":0.504963693498393,"d":"0.50"},"down","yes"]
[69867,0,"chr16","-",1962060,1964803,"ENST00000526522",5,924,"ENSG00000140988","RPS2","GO:0000184(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay);GO:0003723(RNA binding);GO:0003729(mRNA binding);GO:0003735(structural constituent of ribosome);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0005840(ribosome);GO:0005925(focal adhesion);GO:0006364(rRNA processing);GO:0006412(translation);GO:0006413(translational initiation);GO:0006614(SRP-dependent cotranslational protein targeting to membrane);GO:0015935(small ribosomal subunit);GO:0016020(membrane);GO:0017134(fibroblast growth factor binding);GO:0019083(viral transcription);GO:0019899(enzyme binding);GO:0022627(cytosolic small ribosomal subunit);GO:0045202(synapse);GO:0045296(cadherin binding);GO:0051443(positive regulation of ubiquitin-protein transferase activity);GO:0070062(extracellular exosome);GO:0071353(cellular response to interleukin-4);GO:1990904(ribonucleoprotein complex)","03010(Ribosome)","K02981","NA","ribosomal protein S2 [Source:HGNC Symbol;Acc:HGNC:10404]",0,{"v":0.254077,"d":"0.25"},0,{"v":3.583647,"d":"3.58"},{"v":11.361207,"d":"11.36"},0,{"v":0.0170009690292056,"d":"0.02"},{"v":-5.87823920965961,"d":"-5.88"},{"v":0.0137322079289841,"d":"0.01"},{"v":0.508873967234253,"d":"0.51"},"down","yes"]
[149757,0,"chr4","+",8269754,8307098,"ENST00000307358",9,2539,"ENSG00000170801","HTRA3","GO:0004175(endopeptidase activity);GO:0004252(serine-type endopeptidase activity);GO:0005515(protein binding);GO:0005520(insulin-like growth factor binding);GO:0005576(extracellular region);GO:0006508(proteolysis);GO:0008233(peptidase activity);GO:0008236(serine-type peptidase activity);GO:0016787(hydrolase activity);GO:0030512(negative regulation of transforming growth factor beta receptor signaling pathway);GO:0030514(negative regulation of BMP signaling pathway)","NA","K08785","EC:3.4.21.-","HtrA serine peptidase 3 [Source:HGNC Symbol;Acc:HGNC:30406]",{"v":31.34663,"d":"31.35"},{"v":28.20277,"d":"28.20"},{"v":33.300529,"d":"33.30"},{"v":9.868152,"d":"9.87"},{"v":7.99966,"d":"8.00"},{"v":11.377453,"d":"11.38"},{"v":3.17487049612989,"d":"3.17"},{"v":1.66669774514412,"d":"1.67"},{"v":0.0137408577444757,"d":"0.01"},{"v":0.508873967234253,"d":"0.51"},"up","yes"]
[145419,0,"chr3","-",149964935,149970715,"ENST00000481767",3,1620,"ENSG00000070087","PFN2","GO:0003779(actin binding);GO:0003785(actin monomer binding);GO:0005515(protein binding);GO:0005546(phosphatidylinositol-4,5-bisphosphate binding);GO:0005737(cytoplasm);GO:0005856(cytoskeleton);GO:0010633(negative regulation of epithelial cell migration);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016887(ATPase activity);GO:0030036(actin cytoskeleton organization);GO:0030833(regulation of actin filament polymerization);GO:0030837(negative regulation of actin filament polymerization);GO:0030838(positive regulation of actin filament polymerization);GO:0032233(positive regulation of actin filament bundle assembly);GO:0032781(positive regulation of ATPase activity);GO:0033138(positive regulation of peptidyl-serine phosphorylation);GO:0050821(protein stabilization);GO:0051496(positive regulation of stress fiber assembly);GO:0070062(extracellular exosome);GO:0098685(Schaffer collateral - CA1 synapse);GO:0098793(presynapse);GO:0098794(postsynapse);GO:0098885(modification of postsynaptic actin cytoskeleton);GO:0098978(glutamatergic synapse);GO:1900028(negative regulation of ruffle assembly);GO:2000300(regulation of synaptic vesicle exocytosis)","04015(Rap1 signaling pathway);04810(Regulation of actin cytoskeleton);05131(Shigellosis);05132(Salmonella infection)","K05759","NA","profilin 2 [Source:HGNC Symbol;Acc:HGNC:8882]",{"v":51.982319,"d":"51.98"},{"v":54.263889,"d":"54.26"},{"v":1.33073,"d":"1.33"},{"v":7.058671,"d":"7.06"},{"v":0.200311,"d":"0.20"},{"v":0.02698,"d":"0.03"},{"v":14.764960069789,"d":"14.76"},{"v":3.8841055497544,"d":"3.88"},{"v":0.013762254657158,"d":"0.01"},{"v":0.50914736425107,"d":"0.51"},"up","yes"]
[146889,0,"chr3","+",180912672,180977155,"ENST00000445140",16,2651,"ENSG00000114416","FXR1","GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0003729(mRNA binding);GO:0003730(mRNA 3'-UTR binding);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005730(nucleolus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005844(polysome);GO:0006417(regulation of translation);GO:0006915(apoptotic process);GO:0007275(multicellular organism development);GO:0007517(muscle organ development);GO:0014069(postsynaptic density);GO:0016020(membrane);GO:0017148(negative regulation of translation);GO:0030154(cell differentiation);GO:0030424(axon);GO:0030425(dendrite);GO:0033592(RNA strand annealing activity);GO:0035770(ribonucleoprotein granule);GO:0036464(cytoplasmic ribonucleoprotein granule);GO:0042803(protein homodimerization activity);GO:0043025(neuronal cell body);GO:0043034(costamere);GO:0043197(dendritic spine);GO:0043488(regulation of mRNA stability);GO:0045182(translation regulator activity);GO:0045727(positive regulation of translation);GO:0046982(protein heterodimerization activity);GO:0048471(perinuclear region of cytoplasm);GO:0098794(postsynapse);GO:0098978(glutamatergic synapse);GO:2000637(positive regulation of gene silencing by miRNA)","03013(RNA transport)","K15516","NA","FMR1 autosomal homolog 1 [Source:HGNC Symbol;Acc:HGNC:4023]",{"v":4.608033,"d":"4.61"},{"v":6.676993,"d":"6.68"},{"v":2.561995,"d":"2.56"},{"v":17.542076,"d":"17.54"},{"v":8.732231,"d":"8.73"},{"v":25.392115,"d":"25.39"},{"v":0.26800812721268,"d":"0.27"},{"v":-1.89965134453398,"d":"-1.90"},{"v":0.0137774169352085,"d":"0.01"},{"v":0.509189783576931,"d":"0.51"},"down","yes"]
[20134,0,"chr10","-",30844638,31031937,"ENST00000413025",6,3106,"ENSG00000183621","ZNF438","GO:0000981(DNA-binding transcription factor activity, RNA polymerase II-specific);GO:0003676(nucleic acid binding);GO:0003677(DNA binding);GO:0003700(DNA-binding transcription factor activity);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0043565(sequence-specific DNA binding);GO:0045892(negative regulation of transcription, DNA-templated);GO:0045893(positive regulation of transcription, DNA-templated);GO:0045944(positive regulation of transcription by RNA polymerase II);GO:0046872(metal ion binding)","NA","NA","NA","zinc finger protein 438 [Source:HGNC Symbol;Acc:HGNC:21029]",{"v":0.140873,"d":"0.14"},{"v":0.742881,"d":"0.74"},{"v":0.649759,"d":"0.65"},{"v":0.028249,"d":"0.03"},0,{"v":0.073262,"d":"0.07"},{"v":15.1068652658333,"d":"15.11"},{"v":3.91713242153047,"d":"3.92"},{"v":0.0138264994806728,"d":"0.01"},{"v":0.509733017066227,"d":"0.51"},"up","yes"]
[138342,0,"chr3","-",38122711,38137242,"ENST00000627515",13,1862,"ENSG00000060971","ACAA1","GO:0000038(very long-chain fatty acid metabolic process);GO:0003824(catalytic activity);GO:0003988(acetyl-CoA C-acyltransferase activity);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0005777(peroxisome);GO:0005782(peroxisomal matrix);GO:0005829(cytosol);GO:0006625(protein targeting to peroxisome);GO:0006629(lipid metabolic process);GO:0006631(fatty acid metabolic process);GO:0006635(fatty acid beta-oxidation);GO:0008206(bile acid metabolic process);GO:0008775(acetate CoA-transferase activity);GO:0010124(phenylacetate catabolic process);GO:0016020(membrane);GO:0016401(palmitoyl-CoA oxidase activity);GO:0016740(transferase activity);GO:0016746(transferase activity, transferring acyl groups);GO:0016747(transferase activity, transferring acyl groups other than amino-acyl groups);GO:0033540(fatty acid beta-oxidation using acyl-CoA oxidase);GO:0035580(specific granule lumen);GO:0036109(alpha-linolenic acid metabolic process);GO:0043231(intracellular membrane-bounded organelle);GO:0043312(neutrophil degranulation)","00071(Fatty acid degradation);00280(Valine, leucine and isoleucine degradation);00592(alpha-Linolenic acid metabolism);01040(Biosynthesis of unsaturated fatty acids);03320(PPAR signaling pathway);04146(Peroxisome)","NA","NA","acetyl-CoA acyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:82]",{"v":0.093402,"d":"0.09"},{"v":1.924658,"d":"1.92"},{"v":2.697921,"d":"2.70"},{"v":0.067721,"d":"0.07"},0,{"v":0.239205,"d":"0.24"},{"v":15.3652052937842,"d":"15.37"},{"v":3.9415951377275,"d":"3.94"},{"v":0.0138287548572288,"d":"0.01"},{"v":0.509733017066227,"d":"0.51"},"up","yes"]
[103848,0,"chr19","-",40033579,40056205,"ENST00000221355",6,3538,"ENSG00000128000","ZNF780B","GO:0003676(nucleic acid binding);GO:0003677(DNA binding);GO:0005622(intracellular);GO:0005634(nucleus);GO:0006355(regulation of transcription, DNA-templated);GO:0046872(metal ion binding)","05168(Herpes simplex virus 1 infection)","K09228","NA","zinc finger protein 780B [Source:HGNC Symbol;Acc:HGNC:33109]",{"v":0.07638,"d":"0.08"},{"v":0.911561,"d":"0.91"},{"v":0.89249,"d":"0.89"},{"v":0.033539,"d":"0.03"},{"v":0.071073,"d":"0.07"},{"v":0.115606,"d":"0.12"},{"v":8.53895231089193,"d":"8.54"},{"v":3.09405906883833,"d":"3.09"},{"v":0.0138342073995954,"d":"0.01"},{"v":0.509733017066227,"d":"0.51"},"up","yes"]
[82108,0,"chr17","+",17042760,17192648,"ENST00000395811",23,10960,"ENSG00000133030","MPRIP","GO:0003779(actin binding);GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005856(cytoskeleton);GO:0005925(focal adhesion);GO:0015629(actin cytoskeleton);GO:0045296(cadherin binding)","NA","NA","NA","myosin phosphatase Rho interacting protein [Source:HGNC Symbol;Acc:HGNC:30321]",{"v":0.04718,"d":"0.05"},{"v":0.07849,"d":"0.08"},{"v":0.031493,"d":"0.03"},{"v":1.583835,"d":"1.58"},{"v":0.047449,"d":"0.05"},{"v":0.07668,"d":"0.08"},{"v":0.0920177474466675,"d":"0.09"},{"v":-3.44194404943113,"d":"-3.44"},{"v":0.0138723247056755,"d":"0.01"},{"v":0.510619611506781,"d":"0.51"},"down","yes"]
[51155,0,"chr13","-",37562588,37598844,"ENST00000541481",20,3113,"ENSG00000133110","POSTN","GO:0001666(response to hypoxia);GO:0001953(negative regulation of cell-matrix adhesion);GO:0003073(regulation of systemic arterial blood pressure);GO:0005201(extracellular matrix structural constituent);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0005615(extracellular space);GO:0005737(cytoplasm);GO:0005794(Golgi apparatus);GO:0005802(trans-Golgi network);GO:0007155(cell adhesion);GO:0008201(heparin binding);GO:0008593(regulation of Notch signaling pathway);GO:0009612(response to mechanical stimulus);GO:0009888(tissue development);GO:0014850(response to muscle activity);GO:0014911(positive regulation of smooth muscle cell migration);GO:0030198(extracellular matrix organization);GO:0031012(extracellular matrix);GO:0031594(neuromuscular junction);GO:0032355(response to estradiol);GO:0042060(wound healing);GO:0044344(cellular response to fibroblast growth factor stimulus);GO:0046872(metal ion binding);GO:0050839(cell adhesion molecule binding);GO:0062023(collagen-containing extracellular matrix);GO:0071307(cellular response to vitamin K);GO:0071356(cellular response to tumor necrosis factor);GO:0071560(cellular response to transforming growth factor beta stimulus);GO:1900025(negative regulation of substrate adhesion-dependent cell spreading);GO:1904209(positive regulation of chemokine (C-C motif) ligand 2 secretion);GO:1990138(neuron projection extension);GO:1990523(bone regeneration)","NA","NA","NA","periostin [Source:HGNC Symbol;Acc:HGNC:16953]",{"v":16.902107,"d":"16.90"},{"v":15.025216,"d":"15.03"},{"v":13.230084,"d":"13.23"},{"v":3.62894,"d":"3.63"},{"v":3.543684,"d":"3.54"},{"v":5.912467,"d":"5.91"},{"v":3.45105792539005,"d":"3.45"},{"v":1.78703868935489,"d":"1.79"},{"v":0.013891833746325,"d":"0.01"},{"v":0.510820161947357,"d":"0.51"},"up","yes"]
[88009,0,"chr17","-",55392622,55421835,"ENST00000262065",7,2569,"ENSG00000108960","MMD","GO:0004672(protein kinase activity);GO:0005764(lysosome);GO:0005765(lysosomal membrane);GO:0005768(endosome);GO:0005794(Golgi apparatus);GO:0005887(integral component of plasma membrane);GO:0006468(protein phosphorylation);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0019835(cytolysis);GO:0031902(late endosome membrane);GO:0032880(regulation of protein localization);GO:0038023(signaling receptor activity);GO:0045666(positive regulation of neuron differentiation);GO:0045860(positive regulation of protein kinase activity)","NA","K11064","NA","monocyte to macrophage differentiation associated [Source:HGNC Symbol;Acc:HGNC:7153]",{"v":32.309921,"d":"32.31"},{"v":31.581968,"d":"31.58"},{"v":31.227072,"d":"31.23"},{"v":6.439967,"d":"6.44"},{"v":15.482239,"d":"15.48"},{"v":6.369748,"d":"6.37"},{"v":3.36204989588206,"d":"3.36"},{"v":1.74934113564114,"d":"1.75"},{"v":0.013963013391015,"d":"0.01"},{"v":0.512918378660845,"d":"0.51"},"up","yes"]
[56623,0,"chr14","+",51877592,51969800,"ENST00000556752",3,3424,"ENSG00000186469","GNG2","GO:0003924(GTPase activity);GO:0005515(protein binding);GO:0005834(heterotrimeric G-protein complex);GO:0005886(plasma membrane);GO:0006457(protein folding);GO:0007165(signal transduction);GO:0007186(G protein-coupled receptor signaling pathway);GO:0007191(adenylate cyclase-activating dopamine receptor signaling pathway);GO:0007223(Wnt signaling pathway, calcium modulating pathway);GO:0008283(cell population proliferation);GO:0016020(membrane);GO:0030168(platelet activation);GO:0031681(G-protein beta-subunit binding);GO:0070062(extracellular exosome);GO:0071380(cellular response to prostaglandin E stimulus);GO:0071870(cellular response to catecholamine stimulus)","04014(Ras signaling pathway);04062(Chemokine signaling pathway);04151(PI3K-Akt signaling pathway);04371(Apelin signaling pathway);04713(Circadian entrainment);04723(Retrograde endocannabinoid signaling);04724(Glutamatergic synapse);04725(Cholinergic synapse);04726(Serotonergic synapse);04727(GABAergic synapse);04728(Dopaminergic synapse);04926(Relaxin signaling pathway);05032(Morphine addiction);05034(Alcoholism);05163(Human cytomegalovirus infection);05167(Kaposi sarcoma-associated herpesvirus infection);05170(Human immunodeficiency virus 1 infection);05200(Pathways in cancer)","K07826","NA","G protein subunit gamma 2 [Source:HGNC Symbol;Acc:HGNC:4404]",{"v":0.907331,"d":"0.91"},{"v":0.738569,"d":"0.74"},{"v":0.184258,"d":"0.18"},{"v":6.868586,"d":"6.87"},{"v":5.878278,"d":"5.88"},{"v":0.386657,"d":"0.39"},{"v":0.139350140758141,"d":"0.14"},{"v":-2.84321363517281,"d":"-2.84"},{"v":0.014012278130153,"d":"0.01"},{"v":0.514208145927738,"d":"0.51"},"down","yes"]
[108856,0,"chr19","+",57681977,57690648,"ENST00000282296",3,4560,"ENSG00000204519","ZNF551","GO:0000981(DNA-binding transcription factor activity, RNA polymerase II-specific);GO:0003676(nucleic acid binding);GO:0003677(DNA binding);GO:0005622(intracellular);GO:0005634(nucleus);GO:0006355(regulation of transcription, DNA-templated);GO:0006357(regulation of transcription by RNA polymerase II);GO:0046872(metal ion binding)","05168(Herpes simplex virus 1 infection)","K09228","NA","zinc finger protein 551 [Source:HGNC Symbol;Acc:HGNC:25108]",{"v":0.116182,"d":"0.12"},{"v":0.044193,"d":"0.04"},{"v":0.101413,"d":"0.10"},{"v":0.076757,"d":"0.08"},{"v":0.92008,"d":"0.92"},{"v":1.125628,"d":"1.13"},{"v":0.123341492085853,"d":"0.12"},{"v":-3.01926989079267,"d":"-3.02"},{"v":0.0141590502609938,"d":"0.01"},{"v":0.519069925309692,"d":"0.52"},"down","yes"]
[7775,0,"chr1","+",81800397,81992422,"ENST00000370717",22,5873,"ENSG00000117114","ADGRL2","GO:0004888(transmembrane signaling receptor activity);GO:0004930(G protein-coupled receptor activity);GO:0005887(integral component of plasma membrane);GO:0007165(signal transduction);GO:0007166(cell surface receptor signaling pathway);GO:0007186(G protein-coupled receptor signaling pathway);GO:0007189(adenylate cyclase-activating G protein-coupled receptor signaling pathway);GO:0007420(brain development);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016524(latrotoxin receptor activity);GO:0030246(carbohydrate binding);GO:0043005(neuron projection)","NA","K04593","NA","adhesion G protein-coupled receptor L2 [Source:HGNC Symbol;Acc:HGNC:18582]",{"v":3.096226,"d":"3.10"},0,{"v":1.903936,"d":"1.90"},0,0,{"v":0.079672,"d":"0.08"},{"v":62.7593382869766,"d":"62.76"},{"v":5.9717582359899,"d":"5.97"},{"v":0.0141959069566903,"d":"0.01"},{"v":0.519896471508626,"d":"0.52"},"up","yes"]
[133695,0,"chr22","-",31104926,31107528,"ENST00000465536",5,703,"ENSG00000198832","SELENOM","GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0005783(endoplasmic reticulum);GO:0005794(Golgi apparatus);GO:0010269(response to selenium ion);GO:0035264(multicellular organism growth);GO:0035934(corticosterone secretion);GO:0042445(hormone metabolic process);GO:0048471(perinuclear region of cytoplasm);GO:0060612(adipose tissue development)","NA","NA","NA","selenoprotein M [Source:HGNC Symbol;Acc:HGNC:30397]",{"v":7.466339,"d":"7.47"},0,{"v":27.742668,"d":"27.74"},{"v":0.743208,"d":"0.74"},{"v":0.170748,"d":"0.17"},0,{"v":38.5237440314413,"d":"38.52"},{"v":5.26767601699671,"d":"5.27"},{"v":0.01422288176627,"d":"0.01"},{"v":0.52035981326142,"d":"0.52"},"up","yes"]
[189260,0,"chr8","-",53966560,54022265,"ENST00000521086",12,2966,"ENSG00000187735","TCEA1","GO:0003676(nucleic acid binding);GO:0003677(DNA binding);GO:0003746(translation elongation factor activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005669(transcription factor TFIID complex);GO:0005730(nucleolus);GO:0006283(transcription-coupled nucleotide-excision repair);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0006366(transcription by RNA polymerase II);GO:0006368(transcription elongation from RNA polymerase II promoter);GO:0006414(translational elongation);GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:1901919(positive regulation of exoribonuclease activity)","NA","K03145","NA","transcription elongation factor A1 [Source:HGNC Symbol;Acc:HGNC:11612]",{"v":18.569754,"d":"18.57"},{"v":24.357435,"d":"24.36"},{"v":0.005137,"d":"0.01"},{"v":2.224092,"d":"2.22"},{"v":0.305208,"d":"0.31"},{"v":0.676119,"d":"0.68"},{"v":13.3936705310601,"d":"13.39"},{"v":3.74347947984252,"d":"3.74"},{"v":0.0143481574429498,"d":"0.01"},{"v":0.524415050203586,"d":"0.52"},"up","yes"]
[31849,0,"chr11","+",64305572,64316738,"ENST00000406310",7,2218,"ENSG00000173153","ESRRA","GO:0000122(negative regulation of transcription by RNA polymerase II);GO:0000978(RNA polymerase II proximal promoter sequence-specific DNA binding);GO:0000981(DNA-binding transcription factor activity, RNA polymerase II-specific);GO:0001227(DNA-binding transcription repressor activity, RNA polymerase II-specific);GO:0001228(DNA-binding transcription activator activity, RNA polymerase II-specific);GO:0001650(fibrillar center);GO:0003677(DNA binding);GO:0003700(DNA-binding transcription factor activity);GO:0003707(steroid hormone receptor activity);GO:0004879(nuclear receptor activity);GO:0005496(steroid binding);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0006355(regulation of transcription, DNA-templated);GO:0006367(transcription initiation from RNA polymerase II promoter);GO:0007005(mitochondrion organization);GO:0008270(zinc ion binding);GO:0015630(microtubule cytoskeleton);GO:0019904(protein domain specific binding);GO:0030278(regulation of ossification);GO:0030522(intracellular receptor signaling pathway);GO:0032355(response to estradiol);GO:0042127(regulation of cell population proliferation);GO:0043401(steroid hormone mediated signaling pathway);GO:0043565(sequence-specific DNA binding);GO:0045171(intercellular bridge);GO:0045667(regulation of osteoblast differentiation);GO:0045670(regulation of osteoclast differentiation);GO:0045893(positive regulation of transcription, DNA-templated);GO:0045944(positive regulation of transcription by RNA polymerase II);GO:0046872(metal ion binding);GO:0051216(cartilage development);GO:1900078(positive regulation of cellular response to insulin stimulus)","NA","K08552","NA","estrogen related receptor alpha [Source:HGNC Symbol;Acc:HGNC:3471]",{"v":11.133229,"d":"11.13"},{"v":2.003998,"d":"2.00"},{"v":0.442482,"d":"0.44"},{"v":0.254526,"d":"0.25"},{"v":0.984474,"d":"0.98"},{"v":0.300701,"d":"0.30"},{"v":8.81970525446174,"d":"8.82"},{"v":3.14073044319418,"d":"3.14"},{"v":0.014421535291099,"d":"0.01"},{"v":0.526567213191584,"d":"0.53"},"up","yes"]
[36272,0,"chr11","-",112085149,112086722,"ENST00000507614",3,741,"ENSG00000150779","TIMM8B","GO:0005615(extracellular space);GO:0005739(mitochondrion);GO:0005743(mitochondrial inner membrane);GO:0005758(mitochondrial intermembrane space);GO:0006626(protein targeting to mitochondrion);GO:0007605(sensory perception of sound);GO:0008270(zinc ion binding);GO:0015031(protein transport);GO:0016020(membrane);GO:0042719(mitochondrial intermembrane space protein transporter complex);GO:0046872(metal ion binding);GO:0072321(chaperone-mediated protein transport)","NA","K17780","NA","translocase of inner mitochondrial membrane 8 homolog B [Source:HGNC Symbol;Acc:HGNC:11818]",{"v":0.167418,"d":"0.17"},{"v":0.190558,"d":"0.19"},{"v":0.241223,"d":"0.24"},{"v":2.516365,"d":"2.52"},{"v":0.208583,"d":"0.21"},{"v":3.58495,"d":"3.58"},{"v":0.0949617569095412,"d":"0.09"},{"v":-3.39650956291164,"d":"-3.40"},{"v":0.0144613876122904,"d":"0.01"},{"v":0.52749218067722,"d":"0.53"},"down","yes"]
[37170,0,"chr11","-",119096597,119101856,"ENST00000640747",9,1813,"ENSG00000172269","DPAGT1","GO:0003975(UDP-N-acetylglucosamine-dolichyl-phosphate N-acetylglucosaminephosphotransferase activity);GO:0003976(UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0006047(UDP-N-acetylglucosamine metabolic process);GO:0006486(protein glycosylation);GO:0006487(protein N-linked glycosylation);GO:0006488(dolichol-linked oligosaccharide biosynthetic process);GO:0006489(dolichyl diphosphate biosynthetic process);GO:0008963(phospho-N-acetylmuramoyl-pentapeptide-transferase activity);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016740(transferase activity);GO:0016757(transferase activity, transferring glycosyl groups);GO:0019348(dolichol metabolic process);GO:0030176(integral component of endoplasmic reticulum membrane);GO:0043231(intracellular membrane-bounded organelle);GO:0046872(metal ion binding);GO:0051259(protein complex oligomerization)","00510(N-Glycan biosynthesis)","K01001","EC:2.7.8.15","dolichyl-phosphate N-acetylglucosaminephosphotransferase 1 [Source:HGNC Symbol;Acc:HGNC:2995]",{"v":7.060438,"d":"7.06"},0,{"v":4.632599,"d":"4.63"},0,0,{"v":0.200969,"d":"0.20"},{"v":58.183286974608,"d":"58.18"},{"v":5.86253289644788,"d":"5.86"},{"v":0.0145387241892106,"d":"0.01"},{"v":0.529781193374143,"d":"0.53"},"up","yes"]
[48792,0,"chr12","-",120461711,120464943,"ENST00000548792",2,1446,"ENSG00000111786","SRSF9","GO:0000381(regulation of alternative mRNA splicing, via spliceosome);GO:0000398(mRNA splicing, via spliceosome);GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005730(nucleolus);GO:0006376(mRNA splice site selection);GO:0006397(mRNA processing);GO:0006405(RNA export from nucleus);GO:0006406(mRNA export from nucleus);GO:0008380(RNA splicing);GO:0009636(response to toxic substance);GO:0016607(nuclear speck);GO:0019904(protein domain specific binding);GO:0031124(mRNA 3'-end processing);GO:0043279(response to alkaloid);GO:0045292(mRNA cis splicing, via spliceosome);GO:0048025(negative regulation of mRNA splicing, via spliceosome)","03040(Spliceosome);05168(Herpes simplex virus 1 infection)","K21123","NA","serine and arginine rich splicing factor 9 [Source:HGNC Symbol;Acc:HGNC:10791]",{"v":1.900342,"d":"1.90"},{"v":1.362423,"d":"1.36"},{"v":1.661076,"d":"1.66"},{"v":9.960726,"d":"9.96"},{"v":4.268242,"d":"4.27"},{"v":10.744298,"d":"10.74"},{"v":0.197164479808128,"d":"0.20"},{"v":-2.3425284286705,"d":"-2.34"},{"v":0.0145576180065334,"d":"0.01"},{"v":0.529938138454268,"d":"0.53"},"down","yes"]
[55340,0,"chr14","+",24311502,24318036,"ENST00000345363",2,2703,"ENSG00000213903","LTB4R","GO:0000166(nucleotide binding);GO:0001632(leukotriene B4 receptor activity);GO:0004930(G protein-coupled receptor activity);GO:0004966(galanin receptor activity);GO:0004974(leukotriene receptor activity);GO:0005886(plasma membrane);GO:0005887(integral component of plasma membrane);GO:0006936(muscle contraction);GO:0006954(inflammatory response);GO:0006955(immune response);GO:0007165(signal transduction);GO:0007186(G protein-coupled receptor signaling pathway);GO:0007200(phospholipase C-activating G protein-coupled receptor signaling pathway);GO:0007218(neuropeptide signaling pathway);GO:0008528(G protein-coupled peptide receptor activity);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0045121(membrane raft);GO:0061737(leukotriene signaling pathway)","04080(Neuroactive ligand-receptor interaction)","K04296","NA","leukotriene B4 receptor [Source:HGNC Symbol;Acc:HGNC:6713]",{"v":0.492961,"d":"0.49"},{"v":0.562106,"d":"0.56"},{"v":0.448516,"d":"0.45"},0,{"v":0.000136,"d":"0.00"},{"v":0.08643,"d":"0.09"},{"v":17.3692096204052,"d":"17.37"},{"v":4.11846020111383,"d":"4.12"},{"v":0.0145869966440539,"d":"0.01"},{"v":0.530225271760151,"d":"0.53"},"up","yes"]
[153978,0,"chr4","+",108027619,108035105,"ENST00000514776",2,6541,"ENSG00000138796","HADH","GO:0003857(3-hydroxyacyl-CoA dehydrogenase activity);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0005739(mitochondrion);GO:0005759(mitochondrial matrix);GO:0006629(lipid metabolic process);GO:0006631(fatty acid metabolic process);GO:0006635(fatty acid beta-oxidation);GO:0009725(response to hormone);GO:0014823(response to activity);GO:0016491(oxidoreductase activity);GO:0032868(response to insulin);GO:0042493(response to drug);GO:0046676(negative regulation of insulin secretion);GO:0055114(oxidation-reduction process);GO:0070403(NAD+ binding);GO:0120162(positive regulation of cold-induced thermogenesis)","00062(Fatty acid elongation);00071(Fatty acid degradation);00280(Valine, leucine and isoleucine degradation);00310(Lysine degradation);00380(Tryptophan metabolism);00650(Butanoate metabolism)","K00022","EC:1.1.1.35","hydroxyacyl-CoA dehydrogenase [Source:HGNC Symbol;Acc:HGNC:4799]",{"v":0.630453,"d":"0.63"},{"v":1.231062,"d":"1.23"},{"v":0.840499,"d":"0.84"},{"v":0.203448,"d":"0.20"},{"v":0.188504,"d":"0.19"},{"v":0.085412,"d":"0.09"},{"v":5.66028020546166,"d":"5.66"},{"v":2.50087347373274,"d":"2.50"},{"v":0.0184197279962044,"d":"0.02"},{"v":0.625852822302878,"d":"0.63"},"up","yes"]
[181900,0,"chr7","-",100107078,100114558,"ENST00000472509",14,2551,"ENSG00000106290","TAF6","GO:0000124(SAGA complex);GO:0003677(DNA binding);GO:0003700(DNA-binding transcription factor activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005669(transcription factor TFIID complex);GO:0005829(cytosol);GO:0006325(chromatin organization);GO:0006352(DNA-templated transcription, initiation);GO:0006357(regulation of transcription by RNA polymerase II);GO:0006366(transcription by RNA polymerase II);GO:0006367(transcription initiation from RNA polymerase II promoter);GO:0006915(apoptotic process);GO:0017162(aryl hydrocarbon receptor binding);GO:0032991(protein-containing complex);GO:0033276(transcription factor TFTC complex);GO:0042795(snRNA transcription by RNA polymerase II);GO:0045786(negative regulation of cell cycle);GO:0046695(SLIK (SAGA-like) complex);GO:0046982(protein heterodimerization activity);GO:0051123(RNA polymerase II preinitiation complex assembly);GO:0071339(MLL1 complex);GO:1901796(regulation of signal transduction by p53 class mediator)","03022(Basal transcription factors)","K03131","NA","TATA-box binding protein associated factor 6 [Source:HGNC Symbol;Acc:HGNC:11540]",{"v":0.384468,"d":"0.38"},{"v":0.034984,"d":"0.03"},{"v":0.017278,"d":"0.02"},{"v":0.092941,"d":"0.09"},{"v":0.41019,"d":"0.41"},{"v":4.817147,"d":"4.82"},{"v":0.0820878157118857,"d":"0.08"},{"v":-3.60668809099383,"d":"-3.61"},{"v":0.0243826730905063,"d":"0.02"},{"v":0.751312796934362,"d":"0.75"},"down","yes"]
[110860,0,"chr2","-",27381195,27409555,"ENST00000472077",8,3752,"ENSG00000115241","PPM1G","GO:0003824(catalytic activity);GO:0004721(phosphoprotein phosphatase activity);GO:0004722(protein serine/threonine phosphatase activity);GO:0004724(magnesium-dependent protein serine/threonine phosphatase activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0006470(protein dephosphorylation);GO:0007050(cell cycle arrest);GO:0016020(membrane);GO:0016787(hydrolase activity);GO:0035970(peptidyl-threonine dephosphorylation);GO:0043169(cation binding);GO:0046872(metal ion binding)","NA","NA","NA","protein phosphatase, Mg2+/Mn2+ dependent 1G [Source:HGNC Symbol;Acc:HGNC:9278]",{"v":0.201481,"d":"0.20"},{"v":0.097844,"d":"0.10"},{"v":0.389493,"d":"0.39"},{"v":0.192653,"d":"0.19"},{"v":4.134053,"d":"4.13"},{"v":0.406922,"d":"0.41"},{"v":0.145515870702134,"d":"0.15"},{"v":-2.78075158550219,"d":"-2.78"},{"v":0.0326303205527982,"d":"0.03"},{"v":0.923974704351644,"d":"0.92"},"down","yes"]
[60834,0,"chr14","+",103629241,103701514,"ENST00000557450",15,2265,"ENSG00000126214","KLC1","GO:0003774(motor activity);GO:0003777(microtubule motor activity);GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005856(cytoskeleton);GO:0005871(kinesin complex);GO:0005874(microtubule);GO:0006890(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum);GO:0007018(microtubule-based movement);GO:0016020(membrane);GO:0016032(viral process);GO:0019886(antigen processing and presentation of exogenous peptide antigen via MHC class II);GO:0030426(growth cone);GO:0031410(cytoplasmic vesicle);GO:0035617(stress granule disassembly);GO:0042995(cell projection)","05132(Salmonella infection)","K10407","NA","kinesin light chain 1 [Source:HGNC Symbol;Acc:HGNC:6387]",{"v":5.213407,"d":"5.21"},{"v":15.855706,"d":"15.86"},{"v":4.913213,"d":"4.91"},{"v":3.261139,"d":"3.26"},{"v":1.893014,"d":"1.89"},{"v":2.420259,"d":"2.42"},{"v":3.430276303956,"d":"3.43"},{"v":1.77832478814515,"d":"1.78"},{"v":0.0497289581815133,"d":"0.05"},1,"up","yes"]
[29925,0,"chr11","-",47420339,47426225,"ENST00000524447",10,935,"ENSG00000165916","PSMC3","GO:0000165(MAPK cascade);GO:0000166(nucleotide binding);GO:0000209(protein polyubiquitination);GO:0000502(proteasome complex);GO:0000932(P-body);GO:0001824(blastocyst development);GO:0002223(stimulatory C-type lectin receptor signaling pathway);GO:0002479(antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent);GO:0005515(protein binding);GO:0005524(ATP binding);GO:0005576(extracellular region);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0006521(regulation of cellular amino acid metabolic process);GO:0008540(proteasome regulatory particle, base subcomplex);GO:0010972(negative regulation of G2/M transition of mitotic cell cycle);GO:0016020(membrane);GO:0016032(viral process);GO:0016579(protein deubiquitination);GO:0016787(hydrolase activity);GO:0016887(ATPase activity);GO:0022624(proteasome accessory complex);GO:0030163(protein catabolic process);GO:0031145(anaphase-promoting complex-dependent catabolic process);GO:0031146(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process);GO:0033209(tumor necrosis factor-mediated signaling pathway);GO:0034774(secretory granule lumen);GO:0036402(proteasome-activating ATPase activity);GO:0038061(NIK/NF-kappaB signaling);GO:0038095(Fc-epsilon receptor signaling pathway);GO:0042802(identical protein binding);GO:0043161(proteasome-mediated ubiquitin-dependent protein catabolic process);GO:0043312(neutrophil degranulation);GO:0043488(regulation of mRNA stability);GO:0043687(post-translational protein modification);GO:0043921(modulation by host of viral transcription);GO:0045899(positive regulation of RNA polymerase II transcriptional preinitiation complex assembly);GO:0045944(positive regulation of transcription by RNA polymerase II);GO:0050852(T cell receptor signaling pathway);GO:0055085(transmembrane transport);GO:0060071(Wnt signaling pathway, planar cell polarity pathway);GO:0061418(regulation of transcription from RNA polymerase II promoter in response to hypoxia);GO:0070498(interleukin-1-mediated signaling pathway);GO:0090090(negative regulation of canonical Wnt signaling pathway);GO:0090263(positive regulation of canonical Wnt signaling pathway);GO:1901800(positive regulation of proteasomal protein catabolic process);GO:1901990(regulation of mitotic cell cycle phase transition);GO:1902036(regulation of hematopoietic stem cell differentiation);GO:1904813(ficolin-1-rich granule lumen)","03050(Proteasome);05169(Epstein-Barr virus infection)","NA","NA","proteasome 26S subunit, ATPase 3 [Source:HGNC Symbol;Acc:HGNC:9549]",{"v":0.726044,"d":"0.73"},{"v":15.647989,"d":"15.65"},{"v":13.406425,"d":"13.41"},{"v":1.88365,"d":"1.88"},{"v":3.052296,"d":"3.05"},{"v":1.350014,"d":"1.35"},{"v":4.73761493868876,"d":"4.74"},{"v":2.24416094475387,"d":"2.24"},{"v":0.0571781461529974,"d":"0.06"},1,"up","no"]
[122016,0,"chr2","+",218399755,218405941,"ENST00000273062",7,2638,"ENSG00000144579","CTDSP1","GO:0001933(negative regulation of protein phosphorylation);GO:0004721(phosphoprotein phosphatase activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0006357(regulation of transcription by RNA polymerase II);GO:0006470(protein dephosphorylation);GO:0008420(RNA polymerase II CTD heptapeptide repeat phosphatase activity);GO:0016311(dephosphorylation);GO:0016787(hydrolase activity);GO:0016791(phosphatase activity);GO:0045665(negative regulation of neuron differentiation);GO:0046872(metal ion binding);GO:0050768(negative regulation of neurogenesis);GO:0070062(extracellular exosome);GO:2000134(negative regulation of G1/S transition of mitotic cell cycle)","NA","K15731","EC:3.1.3.16","CTD small phosphatase 1 [Source:HGNC Symbol;Acc:HGNC:21614]",{"v":45.887341,"d":"45.89"},{"v":46.325592,"d":"46.33"},{"v":12.561145,"d":"12.56"},{"v":9.777642,"d":"9.78"},{"v":10.138762,"d":"10.14"},{"v":20.101734,"d":"20.10"},{"v":2.6181647431972,"d":"2.62"},{"v":1.38855587906919,"d":"1.39"},{"v":0.0652253091436962,"d":"0.07"},1,"up","no"]
[64613,0,"chr15","-",56630181,56734086,"ENST00000559237",21,4902,"ENSG00000137871","ZNF280D","GO:0000981(DNA-binding transcription factor activity, RNA polymerase II-specific);GO:0003676(nucleic acid binding);GO:0003677(DNA binding);GO:0003700(DNA-binding transcription factor activity);GO:0005634(nucleus);GO:0006355(regulation of transcription, DNA-templated);GO:0006357(regulation of transcription by RNA polymerase II);GO:0046872(metal ion binding)","NA","NA","NA","zinc finger protein 280D [Source:HGNC Symbol;Acc:HGNC:25953]",{"v":0.214907,"d":"0.21"},{"v":0.989644,"d":"0.99"},{"v":1.067213,"d":"1.07"},{"v":0.366351,"d":"0.37"},{"v":0.022513,"d":"0.02"},{"v":0.012885,"d":"0.01"},{"v":5.65468489031709,"d":"5.65"},{"v":2.49944663166987,"d":"2.50"},{"v":0.0732714854413944,"d":"0.07"},1,"up","no"]
[143558,0,"chr3","-",123614029,123884308,"ENST00000464489",33,5901,"ENSG00000065534","MYLK","GO:0000166(nucleotide binding);GO:0001725(stress fiber);GO:0003779(actin binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0004687(myosin light chain kinase activity);GO:0005515(protein binding);GO:0005516(calmodulin binding);GO:0005524(ATP binding);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005856(cytoskeleton);GO:0005886(plasma membrane);GO:0006468(protein phosphorylation);GO:0006936(muscle contraction);GO:0006939(smooth muscle contraction);GO:0014820(tonic smooth muscle contraction);GO:0015629(actin cytoskeleton);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0016740(transferase activity);GO:0030027(lamellipodium);GO:0030335(positive regulation of cell migration);GO:0032060(bleb assembly);GO:0032154(cleavage furrow);GO:0042995(cell projection);GO:0046872(metal ion binding);GO:0051928(positive regulation of calcium ion transport);GO:0060414(aorta smooth muscle tissue morphogenesis);GO:0071476(cellular hypotonic response);GO:0072358(cardiovascular system development);GO:0090303(positive regulation of wound healing)","04020(Calcium signaling pathway);04022(cGMP-PKG signaling pathway);04270(Vascular smooth muscle contraction);04371(Apelin signaling pathway);04510(Focal adhesion);04611(Platelet activation);04810(Regulation of actin cytoskeleton);04921(Oxytocin signaling pathway);04971(Gastric acid secretion)","K00907","EC:2.7.11.18","myosin light chain kinase [Source:HGNC Symbol;Acc:HGNC:7590]",0,{"v":0.189672,"d":"0.19"},0,{"v":0.188478,"d":"0.19"},{"v":0.409937,"d":"0.41"},{"v":1.073207,"d":"1.07"},{"v":0.113465843354538,"d":"0.11"},{"v":-3.13967002679235,"d":"-3.14"},{"v":0.0815913404848215,"d":"0.08"},1,"down","no"]
[179175,0,"chr7","+",55964581,56000181,"ENST00000446778",8,1882,"ENSG00000146729","NIPSNAP2","GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0005739(mitochondrion);GO:0005741(mitochondrial outer membrane);GO:0006119(oxidative phosphorylation);GO:0007005(mitochondrion organization);GO:0016020(membrane);GO:1901843(positive regulation of high voltage-gated calcium channel activity)","NA","NA","NA","nipsnap homolog 2 [Source:HGNC Symbol;Acc:HGNC:4179]",{"v":0.03954,"d":"0.04"},{"v":1.411091,"d":"1.41"},{"v":0.520232,"d":"0.52"},{"v":0.110713,"d":"0.11"},{"v":0.132075,"d":"0.13"},{"v":0.123873,"d":"0.12"},{"v":5.37516397980696,"d":"5.38"},{"v":2.42630876758502,"d":"2.43"},{"v":0.0913498777959062,"d":"0.09"},1,"up","no"]
[152567,0,"chr4","+",81030708,81057632,"ENST00000282701",3,6092,"ENSG00000152785","BMP3","GO:0001501(skeletal system development);GO:0001503(ossification);GO:0001649(osteoblast differentiation);GO:0005102(signaling receptor binding);GO:0005125(cytokine activity);GO:0005160(transforming growth factor beta receptor binding);GO:0005576(extracellular region);GO:0005615(extracellular space);GO:0007267(cell-cell signaling);GO:0007275(multicellular organism development);GO:0008083(growth factor activity);GO:0010469(regulation of signaling receptor activity);GO:0010862(positive regulation of pathway-restricted SMAD protein phosphorylation);GO:0030154(cell differentiation);GO:0042981(regulation of apoptotic process);GO:0043408(regulation of MAPK cascade);GO:0048468(cell development);GO:0051216(cartilage development);GO:0060395(SMAD protein signal transduction);GO:0070062(extracellular exosome);GO:0070700(BMP receptor binding)","04060(Cytokine-cytokine receptor interaction)","NA","NA","bone morphogenetic protein 3 [Source:HGNC Symbol;Acc:HGNC:1070]",{"v":0.643518,"d":"0.64"},{"v":0.63842,"d":"0.64"},{"v":0.498818,"d":"0.50"},{"v":0.17192,"d":"0.17"},{"v":0.220105,"d":"0.22"},{"v":0.17875,"d":"0.18"},{"v":3.11989137576103,"d":"3.12"},{"v":1.64149580011991,"d":"1.64"},{"v":0.109190325108154,"d":"0.11"},1,"up","no"]
[12040,0,"chr1","-",155234452,155244670,"ENST00000327247",12,2387,"ENSG00000177628","GBA","GO:0004348(glucosylceramidase activity);GO:0005102(signaling receptor binding);GO:0005124(scavenger receptor binding);GO:0005515(protein binding);GO:0005615(extracellular space);GO:0005764(lysosome);GO:0005765(lysosomal membrane);GO:0005783(endoplasmic reticulum);GO:0005794(Golgi apparatus);GO:0005802(trans-Golgi network);GO:0006629(lipid metabolic process);GO:0006665(sphingolipid metabolic process);GO:0006680(glucosylceramide catabolic process);GO:0006687(glycosphingolipid metabolic process);GO:0006914(autophagy);GO:0007040(lysosome organization);GO:0008152(metabolic process);GO:0008202(steroid metabolic process);GO:0008203(cholesterol metabolic process);GO:0009267(cellular response to starvation);GO:0009268(response to pH);GO:0016020(membrane);GO:0016241(regulation of macroautophagy);GO:0016740(transferase activity);GO:0016757(transferase activity, transferring glycosyl groups);GO:0016787(hydrolase activity);GO:0016798(hydrolase activity, acting on glycosyl bonds);GO:0019898(extrinsic component of membrane);GO:0023021(termination of signal transduction);GO:0030259(lipid glycosylation);GO:0032006(regulation of TOR signaling);GO:0032268(regulation of cellular protein metabolic process);GO:0032269(negative regulation of cellular protein metabolic process);GO:0032436(positive regulation of proteasomal ubiquitin-dependent protein catabolic process);GO:0032463(negative regulation of protein homooligomerization);GO:0032715(negative regulation of interleukin-6 production);GO:0033561(regulation of water loss via skin);GO:0033574(response to testosterone);GO:0035307(positive regulation of protein dephosphorylation);GO:0043202(lysosomal lumen);GO:0043243(positive regulation of protein complex disassembly);GO:0043407(negative regulation of MAP kinase activity);GO:0043589(skin morphogenesis);GO:0043627(response to estrogen);GO:0046512(sphingosine biosynthetic process);GO:0046513(ceramide biosynthetic process);GO:0046527(glucosyltransferase activity);GO:0050295(steryl-beta-glucosidase activity);GO:0050728(negative regulation of inflammatory response);GO:0051246(regulation of protein metabolic process);GO:0051247(positive regulation of protein metabolic process);GO:0070062(extracellular exosome);GO:0071356(cellular response to tumor necrosis factor);GO:0071548(response to dexamethasone);GO:0097066(response to thyroid hormone);GO:1901215(negative regulation of neuron death);GO:1901805(beta-glucoside catabolic process);GO:1903052(positive regulation of proteolysis involved in cellular protein catabolic process);GO:1903061(positive regulation of protein lipidation);GO:1904457(positive regulation of neuronal action potential);GO:1904925(positive regulation of autophagy of mitochondrion in response to mitochondrial depolarization);GO:1905037(autophagosome organization);GO:1905165(regulation of lysosomal protein catabolic process)","00511(Other glycan degradation);00600(Sphingolipid metabolism);04142(Lysosome)","NA","NA","glucosylceramidase beta [Source:HGNC Symbol;Acc:HGNC:4177]",{"v":2.748951,"d":"2.75"},{"v":16.21909,"d":"16.22"},{"v":3.285979,"d":"3.29"},{"v":6.226545,"d":"6.23"},{"v":28.211481,"d":"28.21"},{"v":23.152445,"d":"23.15"},{"v":0.386418440647933,"d":"0.39"},{"v":-1.37176415082623,"d":"-1.37"},{"v":0.116934212464059,"d":"0.12"},1,"down","no"]
[54601,0,"chr14","-",22900777,22919178,"ENST00000346528",12,2361,"ENSG00000100461","RBM23","GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0003729(mRNA binding);GO:0005515(protein binding);GO:0005634(nucleus);GO:0006397(mRNA processing);GO:0010494(cytoplasmic stress granule);GO:0016020(membrane);GO:0061158(3'-UTR-mediated mRNA destabilization);GO:1990446(U1 snRNP binding);GO:1990904(ribonucleoprotein complex)","NA","NA","NA","RNA binding motif protein 23 [Source:HGNC Symbol;Acc:HGNC:20155]",{"v":10.823473,"d":"10.82"},{"v":6.251509,"d":"6.25"},{"v":5.38662,"d":"5.39"},{"v":1.794563,"d":"1.79"},{"v":3.786563,"d":"3.79"},{"v":3.401304,"d":"3.40"},{"v":2.50061531233753,"d":"2.50"},{"v":1.32228313442029,"d":"1.32"},{"v":0.125550112248257,"d":"0.13"},1,"up","no"]
[3286,0,"chr1","+",27322160,27336400,"ENST00000374076",6,1599,"ENSG00000186501","TMEM222","GO:0016020(membrane);GO:0016021(integral component of membrane)","NA","NA","NA","transmembrane protein 222 [Source:HGNC Symbol;Acc:HGNC:25363]",{"v":5.01534,"d":"5.02"},{"v":1.260373,"d":"1.26"},{"v":1.994123,"d":"1.99"},{"v":0.460587,"d":"0.46"},{"v":0.680056,"d":"0.68"},{"v":1.514364,"d":"1.51"},{"v":3.11480760691026,"d":"3.11"},{"v":1.63914305470081,"d":"1.64"},{"v":0.134190445038753,"d":"0.13"},1,"up","no"]
[99772,0,"chr19","+",13731767,13759153,"ENST00000588071",8,1157,"ENSG00000104957","CCDC130","GO:0005515(protein binding);GO:0005575(cellular_component);GO:0009615(response to virus)","NA","K13115","NA","coiled-coil domain containing 130 [Source:HGNC Symbol;Acc:HGNC:28118]",{"v":2.563893,"d":"2.56"},{"v":2.992883,"d":"2.99"},{"v":0.663875,"d":"0.66"},{"v":0.166645,"d":"0.17"},{"v":0.541331,"d":"0.54"},{"v":1.231287,"d":"1.23"},{"v":3.20773974442868,"d":"3.21"},{"v":1.68155709545453,"d":"1.68"},{"v":0.142721797940657,"d":"0.14"},1,"up","no"]
[172259,0,"chr6","+",85450083,85495784,"ENST00000257770",9,3562,"ENSG00000135318","NT5E","GO:0000166(nucleotide binding);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0006195(purine nucleotide catabolic process);GO:0006196(AMP catabolic process);GO:0006259(DNA metabolic process);GO:0007159(leukocyte cell-cell adhesion);GO:0008253(5'-nucleotidase activity);GO:0009166(nucleotide catabolic process);GO:0009986(cell surface);GO:0016020(membrane);GO:0016311(dephosphorylation);GO:0016787(hydrolase activity);GO:0016788(hydrolase activity, acting on ester bonds);GO:0019674(NAD metabolic process);GO:0031225(anchored component of membrane);GO:0046086(adenosine biosynthetic process);GO:0046135(pyrimidine nucleoside catabolic process);GO:0046872(metal ion binding);GO:0050728(negative regulation of inflammatory response);GO:0070062(extracellular exosome)","00230(Purine metabolism);00240(Pyrimidine metabolism);00760(Nicotinate and nicotinamide metabolism)","K19970","EC:3.1.3.5","5'-nucleotidase ecto [Source:HGNC Symbol;Acc:HGNC:8021]",{"v":45.273914,"d":"45.27"},{"v":36.625237,"d":"36.63"},{"v":32.376755,"d":"32.38"},{"v":72.254189,"d":"72.25"},{"v":60.297062,"d":"60.30"},{"v":74.194405,"d":"74.19"},{"v":0.552736672735702,"d":"0.55"},{"v":-0.855335759847954,"d":"-0.86"},{"v":0.158134109864673,"d":"0.16"},1,"down","no"]
[150008,0,"chr4","+",15003898,15066626,"ENST00000345451",10,2013,"ENSG00000137449","CPEB2","GO:0000900(translation repressor activity, mRNA regulatory element binding);GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0003730(mRNA 3'-UTR binding);GO:0005095(GTPase inhibitor activity);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0006412(translation);GO:0006417(regulation of translation);GO:0008135(translation factor activity, RNA binding);GO:0032869(cellular response to insulin stimulus);GO:0034260(negative regulation of GTPase activity);GO:0034599(cellular response to oxidative stress);GO:0035925(mRNA 3'-UTR AU-rich region binding);GO:0043005(neuron projection);GO:0043022(ribosome binding);GO:0043023(ribosomal large subunit binding);GO:0043024(ribosomal small subunit binding);GO:0045182(translation regulator activity);GO:0045202(synapse);GO:0071243(cellular response to arsenic-containing substance);GO:0071456(cellular response to hypoxia);GO:1900248(negative regulation of cytoplasmic translational elongation);GO:1990124(messenger ribonucleoprotein complex);GO:2000766(negative regulation of cytoplasmic translation)","04114(Oocyte meiosis);04914(Progesterone-mediated oocyte maturation)","K02602","NA","cytoplasmic polyadenylation element binding protein 2 [Source:HGNC Symbol;Acc:HGNC:21745]",{"v":0.504493,"d":"0.50"},{"v":0.173248,"d":"0.17"},{"v":0.296192,"d":"0.30"},{"v":0.83349,"d":"0.83"},{"v":0.37546,"d":"0.38"},{"v":1.471276,"d":"1.47"},{"v":0.363377192818814,"d":"0.36"},{"v":-1.46046022248035,"d":"-1.46"},{"v":0.164950961000738,"d":"0.16"},1,"down","no"]
[112727,0,"chr2","+",60756253,60798468,"ENST00000496283",19,4193,"ENSG00000115421","PAPOLG","GO:0000166(nucleotide binding);GO:0003723(RNA binding);GO:0004652(polynucleotide adenylyltransferase activity);GO:0005524(ATP binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0006378(mRNA polyadenylation);GO:0006397(mRNA processing);GO:0016020(membrane);GO:0016604(nuclear body);GO:0016740(transferase activity);GO:0016779(nucleotidyltransferase activity);GO:0031123(RNA 3'-end processing);GO:0043631(RNA polyadenylation);GO:0046872(metal ion binding)","03015(mRNA surveillance pathway)","K14376","EC:2.7.7.19","poly(A) polymerase gamma [Source:HGNC Symbol;Acc:HGNC:14982]",{"v":0.77646,"d":"0.78"},{"v":0.987826,"d":"0.99"},{"v":0.215749,"d":"0.22"},{"v":0.134701,"d":"0.13"},{"v":0.448645,"d":"0.45"},{"v":0.092365,"d":"0.09"},{"v":2.93029860398898,"d":"2.93"},{"v":1.55104768599356,"d":"1.55"},{"v":0.172966604061051,"d":"0.17"},1,"up","no"]
[159781,0,"chr5","+",70925030,70952347,"ENST00000503079",7,1219,"ENSG00000172062","SMN1","GO:0000245(spliceosomal complex assembly);GO:0000387(spliceosomal snRNP assembly);GO:0003723(RNA binding);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0006353(DNA-templated transcription, termination);GO:0006397(mRNA processing);GO:0007399(nervous system development);GO:0008380(RNA splicing);GO:0015030(Cajal body);GO:0030018(Z disc);GO:0032797(SMN complex);GO:0034719(SMN-Sm protein complex);GO:0036464(cytoplasmic ribonucleoprotein granule);GO:0042802(identical protein binding);GO:0042995(cell projection);GO:0043005(neuron projection);GO:0043204(perikaryon);GO:0051170(import into nucleus);GO:0097504(Gemini of coiled bodies)","03013(RNA transport)","K13129","NA","survival of motor neuron 1, telomeric [Source:HGNC Symbol;Acc:HGNC:11117]",{"v":4.820838,"d":"4.82"},{"v":0.925029,"d":"0.93"},{"v":1.651937,"d":"1.65"},{"v":0.758258,"d":"0.76"},{"v":1.348508,"d":"1.35"},{"v":0.543625,"d":"0.54"},{"v":2.79121231546591,"d":"2.79"},{"v":1.48089186815882,"d":"1.48"},{"v":0.181339700720641,"d":"0.18"},1,"up","no"]
[37735,0,"chr11","+",124876842,124881465,"ENST00000525482",11,1645,"ENSG00000154134","ROBO3","GO:0005515(protein binding);GO:0005886(plasma membrane);GO:0006935(chemotaxis);GO:0007156(homophilic cell adhesion via plasma membrane adhesion molecules);GO:0007275(multicellular organism development);GO:0007399(nervous system development);GO:0007411(axon guidance);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016199(axon midline choice point recognition);GO:0030154(cell differentiation);GO:0030424(axon);GO:0035385(Roundabout signaling pathway);GO:0061642(chemoattraction of axon);GO:0070593(dendrite self-avoidance);GO:0071679(commissural neuron axon guidance);GO:0098632(cell-cell adhesion mediator activity)","04360(Axon guidance)","K06755","NA","roundabout guidance receptor 3 [Source:HGNC Symbol;Acc:HGNC:13433]",{"v":0.557116,"d":"0.56"},{"v":1.678932,"d":"1.68"},{"v":0.710305,"d":"0.71"},0,{"v":0.534566,"d":"0.53"},0,{"v":5.51167302073084,"d":"5.51"},{"v":2.46249030288935,"d":"2.46"},{"v":0.189022625352907,"d":"0.19"},1,"up","no"]
[105407,0,"chr19","-",45831170,45863132,"ENST00000598896",12,1899,"ENSG00000125755","SYMPK","GO:0000398(mRNA splicing, via spliceosome);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005856(cytoskeleton);GO:0005886(plasma membrane);GO:0005923(bicellular tight junction);GO:0006369(termination of RNA polymerase II transcription);GO:0006378(mRNA polyadenylation);GO:0006397(mRNA processing);GO:0006406(mRNA export from nucleus);GO:0007155(cell adhesion);GO:0016020(membrane);GO:0030054(cell junction);GO:0031124(mRNA 3'-end processing);GO:0032091(negative regulation of protein binding);GO:0035307(positive regulation of protein dephosphorylation);GO:0097165(nuclear stress granule)","03015(mRNA surveillance pathway);04530(Tight junction)","NA","NA","symplekin [Source:HGNC Symbol;Acc:HGNC:22935]",{"v":0.672539,"d":"0.67"},{"v":1.018074,"d":"1.02"},{"v":0.488678,"d":"0.49"},{"v":0.40299,"d":"0.40"},{"v":0.258052,"d":"0.26"},{"v":0.022283,"d":"0.02"},{"v":3.18924523469798,"d":"3.19"},{"v":1.67321503684377,"d":"1.67"},{"v":0.204294845389872,"d":"0.20"},1,"up","no"]
[178573,0,"chr7","-",44114681,44123559,"ENST00000610533",11,1619,"ENSG00000106628","POLD2","GO:0000723(telomere maintenance);GO:0003677(DNA binding);GO:0003887(DNA-directed DNA polymerase activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0006260(DNA replication);GO:0006261(DNA-dependent DNA replication);GO:0006271(DNA strand elongation involved in DNA replication);GO:0006281(DNA repair);GO:0006283(transcription-coupled nucleotide-excision repair);GO:0006296(nucleotide-excision repair, DNA incision, 5'-to lesion);GO:0006297(nucleotide-excision repair, DNA gap filling);GO:0006298(mismatch repair);GO:0006974(cellular response to DNA damage stimulus);GO:0019985(translesion synthesis);GO:0032201(telomere maintenance via semi-conservative replication);GO:0033683(nucleotide-excision repair, DNA incision);GO:0042769(DNA damage response, detection of DNA damage);GO:0043625(delta DNA polymerase complex);GO:0071897(DNA biosynthetic process)","03030(DNA replication);03410(Base excision repair);03420(Nucleotide excision repair);03430(Mismatch repair);03440(Homologous recombination)","K02328","NA","DNA polymerase delta 2, accessory subunit [Source:HGNC Symbol;Acc:HGNC:9176]",{"v":2.282434,"d":"2.28"},{"v":1.713428,"d":"1.71"},{"v":8.800787,"d":"8.80"},{"v":1.317194,"d":"1.32"},{"v":1.555817,"d":"1.56"},{"v":2.253456,"d":"2.25"},{"v":2.49619260203957,"d":"2.50"},{"v":1.31972925442742,"d":"1.32"},{"v":0.211670396585168,"d":"0.21"},1,"up","no"]
[126062,0,"chr20","+",33490087,33645541,"ENST00000342704",11,2864,"ENSG00000078699","CBFA2T2","GO:0000122(negative regulation of transcription by RNA polymerase II);GO:0003700(DNA-binding transcription factor activity);GO:0003714(transcription corepressor activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0006355(regulation of transcription, DNA-templated);GO:0010976(positive regulation of neuron projection development);GO:0010977(negative regulation of neuron projection development);GO:0030855(epithelial cell differentiation);GO:0045746(negative regulation of Notch signaling pathway);GO:0045892(negative regulation of transcription, DNA-templated);GO:0046872(metal ion binding);GO:0060575(intestinal epithelial cell differentiation)","NA","K22751","NA","CBFA2/RUNX1 translocation partner 2 [Source:HGNC Symbol;Acc:HGNC:1536]",{"v":0.416029,"d":"0.42"},{"v":1.82316,"d":"1.82"},{"v":0.038264,"d":"0.04"},{"v":2.413118,"d":"2.41"},{"v":2.164429,"d":"2.16"},{"v":1.703003,"d":"1.70"},{"v":0.362619993471909,"d":"0.36"},{"v":-1.46346962295595,"d":"-1.46"},{"v":0.219414724444866,"d":"0.22"},1,"down","no"]
[2454,0,"chr1","-",20807319,21176836,"ENST00000634879",34,5325,"ENSG00000075151","EIF4G3","GO:0000339(RNA cap binding);GO:0003723(RNA binding);GO:0003729(mRNA binding);GO:0003743(translation initiation factor activity);GO:0005515(protein binding);GO:0005829(cytosol);GO:0006412(translation);GO:0006413(translational initiation);GO:0006417(regulation of translation);GO:0006446(regulation of translational initiation);GO:0008135(translation factor activity, RNA binding);GO:0016281(eukaryotic translation initiation factor 4F complex)","03013(RNA transport);05416(Viral myocarditis)","K03260","NA","eukaryotic translation initiation factor 4 gamma 3 [Source:HGNC Symbol;Acc:HGNC:3298]",{"v":1.415487,"d":"1.42"},{"v":0.264631,"d":"0.26"},{"v":0.214491,"d":"0.21"},{"v":0.226839,"d":"0.23"},{"v":0.232818,"d":"0.23"},{"v":0.275132,"d":"0.28"},{"v":2.57843952481597,"d":"2.58"},{"v":1.36649820870515,"d":"1.37"},{"v":0.2258517070097,"d":"0.23"},1,"up","no"]
[31124,0,"chr11","+",61615036,61639449,"ENST00000496593",5,3525,"ENSG00000243742","RPLP0P2","NA","NA","NA","NA","ribosomal protein lateral stalk subunit P0 pseudogene 2 [Source:HGNC Symbol;Acc:HGNC:17960]",{"v":0.100558,"d":"0.10"},{"v":0.112782,"d":"0.11"},{"v":0.113763,"d":"0.11"},{"v":0.296485,"d":"0.30"},{"v":0.273526,"d":"0.27"},{"v":0.271756,"d":"0.27"},{"v":0.388590904608995,"d":"0.39"},{"v":-1.36367596140894,"d":"-1.36"},{"v":0.233215071276181,"d":"0.23"},1,"down","no"]
[174990,0,"chr6","-",151404854,151452126,"ENST00000367303",12,1856,"ENSG00000155906","RMND1","GO:0005515(protein binding);GO:0005739(mitochondrion);GO:0006412(translation);GO:0070131(positive regulation of mitochondrial translation)","NA","NA","NA","required for meiotic nuclear division 1 homolog [Source:HGNC Symbol;Acc:HGNC:21176]",{"v":3.819256,"d":"3.82"},{"v":0.197497,"d":"0.20"},{"v":0.121448,"d":"0.12"},{"v":0.038657,"d":"0.04"},{"v":0.821506,"d":"0.82"},{"v":0.454763,"d":"0.45"},{"v":3.14709801159913,"d":"3.15"},{"v":1.6540221098871,"d":"1.65"},{"v":0.247171655822968,"d":"0.25"},1,"up","no"]
[68690,0,"chr15","+",98648539,98964530,"ENST00000650285",21,12235,"ENSG00000140443","IGF1R","GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0004713(protein tyrosine kinase activity);GO:0004714(transmembrane receptor protein tyrosine kinase activity);GO:0005009(insulin-activated receptor activity);GO:0005010(insulin-like growth factor-activated receptor activity);GO:0005158(insulin receptor binding);GO:0005515(protein binding);GO:0005520(insulin-like growth factor binding);GO:0005524(ATP binding);GO:0005886(plasma membrane);GO:0005887(integral component of plasma membrane);GO:0005899(insulin receptor complex);GO:0006468(protein phosphorylation);GO:0006955(immune response);GO:0007165(signal transduction);GO:0007169(transmembrane receptor protein tyrosine kinase signaling pathway);GO:0008284(positive regulation of cell population proliferation);GO:0008286(insulin receptor signaling pathway);GO:0014065(phosphatidylinositol 3-kinase signaling);GO:0014068(positive regulation of phosphatidylinositol 3-kinase signaling);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0016740(transferase activity);GO:0018108(peptidyl-tyrosine phosphorylation);GO:0030335(positive regulation of cell migration);GO:0030424(axon);GO:0031994(insulin-like growth factor I binding);GO:0035867(alphav-beta3 integrin-IGF-1-IGF1R complex);GO:0038083(peptidyl-tyrosine autophosphorylation);GO:0042593(glucose homeostasis);GO:0042802(identical protein binding);GO:0043066(negative regulation of apoptotic process);GO:0043231(intracellular membrane-bounded organelle);GO:0043235(receptor complex);GO:0043243(positive regulation of protein complex disassembly);GO:0043410(positive regulation of MAPK cascade);GO:0043548(phosphatidylinositol 3-kinase binding);GO:0043559(insulin binding);GO:0043560(insulin receptor substrate binding);GO:0046328(regulation of JNK cascade);GO:0046777(protein autophosphorylation);GO:0048009(insulin-like growth factor receptor signaling pathway);GO:0048015(phosphatidylinositol-mediated signaling);GO:0048856(anatomical structure development);GO:0051262(protein tetramerization);GO:0051389(inactivation of MAPKK activity);GO:0051897(positive regulation of protein kinase B signaling);GO:0071333(cellular response to glucose stimulus);GO:0097062(dendritic spine maintenance);GO:0097242(amyloid-beta clearance);GO:0120162(positive regulation of cold-induced thermogenesis);GO:1904646(cellular response to amyloid-beta)","01521(EGFR tyrosine kinase inhibitor resistance);01522(Endocrine resistance);04010(MAPK signaling pathway);04014(Ras signaling pathway);04015(Rap1 signaling pathway);04066(HIF-1 signaling pathway);04068(FoxO signaling pathway);04114(Oocyte meiosis);04140(Autophagy - animal);04144(Endocytosis);04150(mTOR signaling pathway);04151(PI3K-Akt signaling pathway);04152(AMPK signaling pathway);04211(Longevity regulating pathway);04213(Longevity regulating pathway - multiple species);04510(Focal adhesion);04520(Adherens junction);04550(Signaling pathways regulating pluripotency of stem cells);04730(Long-term depression);04913(Ovarian steroidogenesis);04914(Progesterone-mediated oocyte maturation);05200(Pathways in cancer);05202(Transcriptional misregulation in cancer);05205(Proteoglycans in cancer);05214(Glioma);05215(Prostate cancer);05218(Melanoma);05224(Breast cancer);05225(Hepatocellular carcinoma)","K05087","EC:2.7.10.1","insulin like growth factor 1 receptor [Source:HGNC Symbol;Acc:HGNC:5465]",{"v":0.40801,"d":"0.41"},{"v":0.081767,"d":"0.08"},{"v":1.174186,"d":"1.17"},{"v":1.659053,"d":"1.66"},{"v":0.951624,"d":"0.95"},{"v":0.982205,"d":"0.98"},{"v":0.463127650727188,"d":"0.46"},{"v":-1.11051820013011,"d":"-1.11"},{"v":0.253065211565642,"d":"0.25"},1,"down","no"]
[145784,0,"chr3","-",157147796,157152501,"ENST00000471247",4,3671,"ENSG00000163660","CCNL1","GO:0000079(regulation of cyclin-dependent protein serine/threonine kinase activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0006355(regulation of transcription, DNA-templated);GO:0006357(regulation of transcription by RNA polymerase II);GO:0006396(RNA processing);GO:0016538(cyclin-dependent protein serine/threonine kinase regulator activity);GO:0016607(nuclear speck)","NA","NA","NA","cyclin L1 [Source:HGNC Symbol;Acc:HGNC:20569]",{"v":3.550128,"d":"3.55"},{"v":3.629316,"d":"3.63"},{"v":1.337299,"d":"1.34"},{"v":1.900506,"d":"1.90"},{"v":1.282935,"d":"1.28"},{"v":0.800838,"d":"0.80"},{"v":2.13758700131191,"d":"2.14"},{"v":1.0959831399082,"d":"1.10"},{"v":0.259709443265626,"d":"0.26"},1,"up","no"]
[32050,0,"chr11","+",65014180,65022184,"ENST00000529384",6,830,"ENSG00000213465","ARL2","GO:0000166(nucleotide binding);GO:0003924(GTPase activity);GO:0005095(GTPase inhibitor activity);GO:0005515(protein binding);GO:0005525(GTP binding);GO:0005634(nucleus);GO:0005730(nucleolus);GO:0005737(cytoplasm);GO:0005739(mitochondrion);GO:0005758(mitochondrial intermembrane space);GO:0005759(mitochondrial matrix);GO:0005794(Golgi apparatus);GO:0005813(centrosome);GO:0005815(microtubule organizing center);GO:0005829(cytosol);GO:0005856(cytoskeleton);GO:0005925(focal adhesion);GO:0007021(tubulin complex assembly);GO:0007049(cell cycle);GO:0007098(centrosome cycle);GO:0010811(positive regulation of cell-substrate adhesion);GO:0016328(lateral plasma membrane);GO:0031113(regulation of microtubule polymerization);GO:0031116(positive regulation of microtubule polymerization);GO:0034260(negative regulation of GTPase activity);GO:0050796(regulation of insulin secretion);GO:0051457(maintenance of protein location in nucleus);GO:0070830(bicellular tight junction assembly)","NA","NA","NA","ADP ribosylation factor like GTPase 2 [Source:HGNC Symbol;Acc:HGNC:693]",{"v":4.109708,"d":"4.11"},{"v":1.040599,"d":"1.04"},{"v":3.280304,"d":"3.28"},{"v":1.24856,"d":"1.25"},{"v":1.181161,"d":"1.18"},{"v":1.313384,"d":"1.31"},{"v":2.25230416993378,"d":"2.25"},{"v":1.17140167414215,"d":"1.17"},{"v":0.265560536902529,"d":"0.27"},1,"up","no"]
[49399,0,"chr12","-",123289109,123350441,"ENST00000420886",31,10981,"ENSG00000139697","SBNO1","GO:0003674(molecular_function);GO:0005575(cellular_component);GO:0005634(nucleus);GO:0006355(regulation of transcription, DNA-templated);GO:0008150(biological_process)","NA","NA","NA","strawberry notch homolog 1 [Source:HGNC Symbol;Acc:HGNC:22973]",{"v":1.918395,"d":"1.92"},{"v":0.212984,"d":"0.21"},{"v":1.422621,"d":"1.42"},{"v":2.324177,"d":"2.32"},{"v":2.486781,"d":"2.49"},{"v":2.003389,"d":"2.00"},{"v":0.521546672043557,"d":"0.52"},{"v":-0.939131732817421,"d":"-0.94"},{"v":0.272015351629809,"d":"0.27"},1,"down","no"]
[66802,0,"chr15","+",75843307,75901044,"ENST00000569423",12,2969,"ENSG00000140367","UBE2Q2","GO:0000166(nucleotide binding);GO:0004842(ubiquitin-protein transferase activity);GO:0005524(ATP binding);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0016567(protein ubiquitination);GO:0016740(transferase activity);GO:0061631(ubiquitin conjugating enzyme activity);GO:0070936(protein K48-linked ubiquitination)","04120(Ubiquitin mediated proteolysis)","K10582","EC:2.3.2.23","ubiquitin conjugating enzyme E2 Q2 [Source:HGNC Symbol;Acc:HGNC:19248]",{"v":18.85635,"d":"18.86"},{"v":4.637082,"d":"4.64"},{"v":12.444377,"d":"12.44"},{"v":18.220774,"d":"18.22"},{"v":23.04031,"d":"23.04"},{"v":19.320084,"d":"19.32"},{"v":0.59321749953715,"d":"0.59"},{"v":-0.753366937885307,"d":"-0.75"},{"v":0.286475033445211,"d":"0.29"},1,"down","no"]
[128684,0,"chr20","+",63553715,63556668,"ENST00000615526",1,2954,"ENSG00000125531","FNDC11","GO:0005515(protein binding)","NA","NA","NA","fibronectin type III domain containing 11 [Source:HGNC Symbol;Acc:HGNC:28764]",{"v":0.148449,"d":"0.15"},{"v":0.103704,"d":"0.10"},{"v":0.10419,"d":"0.10"},{"v":0.339637,"d":"0.34"},{"v":0.219518,"d":"0.22"},{"v":0.297714,"d":"0.30"},{"v":0.415866369304993,"d":"0.42"},{"v":-1.26580807448278,"d":"-1.27"},{"v":0.292778073181115,"d":"0.29"},1,"down","no"]
[69925,0,"chr16","-",1997655,2009821,"ENST00000562103",12,3368,"ENSG00000167962","ZNF598","GO:0003676(nucleic acid binding)","NA","K22381","EC:2.3.2.27","zinc finger protein 598 [Source:HGNC Symbol;Acc:HGNC:28079]",{"v":1.608764,"d":"1.61"},{"v":1.621672,"d":"1.62"},{"v":1.804099,"d":"1.80"},{"v":0.019632,"d":"0.02"},{"v":0.130067,"d":"0.13"},{"v":1.786319,"d":"1.79"},{"v":2.60045877672625,"d":"2.60"},{"v":1.37876616806909,"d":"1.38"},{"v":0.299597651757866,"d":"0.30"},1,"up","no"]
[58596,0,"chr14","-",75086429,75127045,"ENST00000556170",19,3975,"ENSG00000119638","NEK9","GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005515(protein binding);GO:0005524(ATP binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005813(centrosome);GO:0005829(cytosol);GO:0006468(protein phosphorylation);GO:0007049(cell cycle);GO:0007077(mitotic nuclear envelope disassembly);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0016740(transferase activity);GO:0019901(protein kinase binding);GO:0046872(metal ion binding);GO:0051301(cell division)","NA","K20878","EC:2.7.11.1","NIMA related kinase 9 [Source:HGNC Symbol;Acc:HGNC:18591]",{"v":0.319565,"d":"0.32"},{"v":0.274193,"d":"0.27"},{"v":0.320862,"d":"0.32"},{"v":0.288871,"d":"0.29"},{"v":0.04482,"d":"0.04"},{"v":0.015324,"d":"0.02"},{"v":2.62057504691775,"d":"2.62"},{"v":1.38988342485668,"d":"1.39"},{"v":0.305407944922662,"d":"0.31"},1,"up","no"]
[114852,0,"chr2","+",87584098,87607265,"ENST00000642872",2,1848,"ENSG00000222041","CYTOR","NA","NA","NA","NA","cytoskeleton regulator RNA [Source:HGNC Symbol;Acc:HGNC:28717]",0,{"v":0.226564,"d":"0.23"},{"v":0.741596,"d":"0.74"},{"v":0.639528,"d":"0.64"},{"v":0.867937,"d":"0.87"},{"v":1.021713,"d":"1.02"},{"v":0.382796307733185,"d":"0.38"},{"v":-1.38535118053028,"d":"-1.39"},{"v":0.311370490571422,"d":"0.31"},1,"down","no"]
[7895,0,"chr1","-",84925583,84997113,"ENST00000370608",14,3044,"ENSG00000153898","MCOLN2","GO:0002250(adaptive immune response);GO:0002376(immune system process);GO:0005261(cation channel activity);GO:0005262(calcium channel activity);GO:0005764(lysosome);GO:0005768(endosome);GO:0005886(plasma membrane);GO:0006811(ion transport);GO:0006816(calcium ion transport);GO:0015031(protein transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0031902(late endosome membrane);GO:0032722(positive regulation of chemokine production);GO:0034220(ion transmembrane transport);GO:0035926(chemokine (C-C motif) ligand 2 secretion);GO:0045087(innate immune response);GO:0051209(release of sequestered calcium ion into cytosol);GO:0051259(protein complex oligomerization);GO:0055037(recycling endosome);GO:0055038(recycling endosome membrane);GO:0070588(calcium ion transmembrane transport);GO:0071639(positive regulation of monocyte chemotactic protein-1 production);GO:0071642(positive regulation of macrophage inflammatory protein 1 alpha production);GO:0071651(positive regulation of chemokine (C-C motif) ligand 5 production);GO:0072345(NAADP-sensitive calcium-release channel activity);GO:0098655(cation transmembrane transport);GO:1905517(macrophage migration);GO:1990266(neutrophil migration);GO:2000343(positive regulation of chemokine (C-X-C motif) ligand 2 production)","NA","K04993","NA","mucolipin 2 [Source:HGNC Symbol;Acc:HGNC:13357]",{"v":0.232927,"d":"0.23"},{"v":0.241793,"d":"0.24"},{"v":0.208895,"d":"0.21"},{"v":0.444503,"d":"0.44"},{"v":0.517222,"d":"0.52"},{"v":0.389654,"d":"0.39"},{"v":0.505864750007215,"d":"0.51"},{"v":-0.983176383043219,"d":"-0.98"},{"v":0.324071626659234,"d":"0.32"},1,"down","no"]
[106013,0,"chr19","-",48615366,48619177,"ENST00000549273",6,1036,"ENSG00000063177","RPL18","GO:0000184(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay);GO:0002181(cytoplasmic translation);GO:0003723(RNA binding);GO:0003735(structural constituent of ribosome);GO:0005622(intracellular);GO:0005634(nucleus);GO:0005730(nucleolus);GO:0005737(cytoplasm);GO:0005783(endoplasmic reticulum);GO:0005791(rough endoplasmic reticulum);GO:0005829(cytosol);GO:0005840(ribosome);GO:0005925(focal adhesion);GO:0006412(translation);GO:0006413(translational initiation);GO:0006614(SRP-dependent cotranslational protein targeting to membrane);GO:0016020(membrane);GO:0019083(viral transcription);GO:0022625(cytosolic large ribosomal subunit);GO:0042788(polysomal ribosome)","03010(Ribosome)","K02883","NA","ribosomal protein L18 [Source:HGNC Symbol;Acc:HGNC:10310]",{"v":2.449746,"d":"2.45"},{"v":3.81943,"d":"3.82"},{"v":1.053502,"d":"1.05"},{"v":1.721005,"d":"1.72"},{"v":0.18184,"d":"0.18"},{"v":1.445666,"d":"1.45"},{"v":2.1868460339536,"d":"2.19"},{"v":1.12885165025758,"d":"1.13"},{"v":0.329876359223473,"d":"0.33"},1,"up","no"]
[145905,0,"chr3","+",158644528,158682433,"ENST00000478576",14,2147,"ENSG00000168827","GFM1","GO:0000166(nucleotide binding);GO:0003723(RNA binding);GO:0003746(translation elongation factor activity);GO:0003924(GTPase activity);GO:0005515(protein binding);GO:0005525(GTP binding);GO:0005622(intracellular);GO:0005739(mitochondrion);GO:0005759(mitochondrial matrix);GO:0006412(translation);GO:0006414(translational elongation);GO:0070125(mitochondrial translational elongation)","NA","K02355","NA","G elongation factor mitochondrial 1 [Source:HGNC Symbol;Acc:HGNC:13780]",{"v":1.416337,"d":"1.42"},{"v":1.348199,"d":"1.35"},{"v":0.00266,"d":"0.00"},{"v":1.395284,"d":"1.40"},{"v":1.29424,"d":"1.29"},{"v":4.127881,"d":"4.13"},{"v":0.405901659062356,"d":"0.41"},{"v":-1.30079785803938,"d":"-1.30"},{"v":0.335357352091756,"d":"0.34"},1,"down","no"]
[44082,0,"chr12","+",55966800,55972385,"ENST00000555408",6,2598,"ENSG00000123374","CDK2","GO:0000082(G1/S transition of mitotic cell cycle);GO:0000086(G2/M transition of mitotic cell cycle);GO:0000122(negative regulation of transcription by RNA polymerase II);GO:0000166(nucleotide binding);GO:0000287(magnesium ion binding);GO:0000307(cyclin-dependent protein kinase holoenzyme complex);GO:0000781(chromosome, telomeric region);GO:0000793(condensed chromosome);GO:0000805(X chromosome);GO:0000806(Y chromosome);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0004693(cyclin-dependent protein serine/threonine kinase activity);GO:0005515(protein binding);GO:0005524(ATP binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005667(transcription factor complex);GO:0005737(cytoplasm);GO:0005768(endosome);GO:0005813(centrosome);GO:0005815(microtubule organizing center);GO:0005829(cytosol);GO:0005856(cytoskeleton);GO:0006260(DNA replication);GO:0006281(DNA repair);GO:0006468(protein phosphorylation);GO:0006813(potassium ion transport);GO:0006974(cellular response to DNA damage stimulus);GO:0006977(DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest);GO:0007049(cell cycle);GO:0007099(centriole replication);GO:0007265(Ras protein signal transduction);GO:0008284(positive regulation of cell population proliferation);GO:0010389(regulation of G2/M transition of mitotic cell cycle);GO:0015030(Cajal body);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0016572(histone phosphorylation);GO:0016740(transferase activity);GO:0018105(peptidyl-serine phosphorylation);GO:0019904(protein domain specific binding);GO:0030332(cyclin binding);GO:0031145(anaphase-promoting complex-dependent catabolic process);GO:0031571(mitotic G1 DNA damage checkpoint);GO:0032298(positive regulation of DNA-dependent DNA replication initiation);GO:0035173(histone kinase activity);GO:0045893(positive regulation of transcription, DNA-templated);GO:0046872(metal ion binding);GO:0051298(centrosome duplication);GO:0051301(cell division);GO:0051321(meiotic cell cycle);GO:0051726(regulation of cell cycle);GO:0060968(regulation of gene silencing);GO:0071732(cellular response to nitric oxide);GO:0097123(cyclin A1-CDK2 complex);GO:0097124(cyclin A2-CDK2 complex);GO:0097134(cyclin E1-CDK2 complex);GO:0097135(cyclin E2-CDK2 complex);GO:0097472(cyclin-dependent protein kinase activity);GO:1901796(regulation of signal transduction by p53 class mediator)","04068(FoxO signaling pathway);04110(Cell cycle);04114(Oocyte meiosis);04115(p53 signaling pathway);04151(PI3K-Akt signaling pathway);04218(Cellular senescence);04914(Progesterone-mediated oocyte maturation);04934(Cushing syndrome);05160(Hepatitis C);05161(Hepatitis B);05162(Measles);05165(Human papillomavirus infection);05166(Human T-cell leukemia virus 1 infection);05169(Epstein-Barr virus infection);05200(Pathways in cancer);05203(Viral carcinogenesis);05215(Prostate cancer);05222(Small cell lung cancer);05226(Gastric cancer)","NA","NA","cyclin dependent kinase 2 [Source:HGNC Symbol;Acc:HGNC:1771]",{"v":0.433896,"d":"0.43"},{"v":0.10939,"d":"0.11"},{"v":0.212914,"d":"0.21"},{"v":0.546224,"d":"0.55"},{"v":0.341416,"d":"0.34"},{"v":0.654525,"d":"0.65"},{"v":0.49034960591117,"d":"0.49"},{"v":-1.02811737653942,"d":"-1.03"},{"v":0.341681520368688,"d":"0.34"},1,"down","no"]
[91662,0,"chr17","+",81637198,81648748,"ENST00000574882",4,1837,"ENSG00000182612","TSPAN10","GO:0016020(membrane);GO:0016021(integral component of membrane)","NA","K17351","NA","tetraspanin 10 [Source:HGNC Symbol;Acc:HGNC:29942]",{"v":0.407188,"d":"0.41"},{"v":0.644977,"d":"0.64"},{"v":0.711454,"d":"0.71"},{"v":0.944745,"d":"0.94"},{"v":1.048138,"d":"1.05"},{"v":1.296018,"d":"1.30"},{"v":0.536233532113007,"d":"0.54"},{"v":-0.899066657177193,"d":"-0.90"},{"v":0.346271186745271,"d":"0.35"},1,"down","no"]
[111867,0,"chr2","+",43637308,43765792,"ENST00000405000",30,6685,"ENSG00000152527","PLEKHH2","GO:0003779(actin binding);GO:0005515(protein binding);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005856(cytoskeleton);GO:0005886(plasma membrane);GO:0016020(membrane);GO:0016604(nuclear body);GO:0030027(lamellipodium);GO:0030835(negative regulation of actin filament depolymerization);GO:0030864(cortical actin cytoskeleton);GO:0042802(identical protein binding);GO:0042995(cell projection)","NA","NA","NA","pleckstrin homology, MyTH4 and FERM domain containing H2 [Source:HGNC Symbol;Acc:HGNC:30506]",{"v":0.597305,"d":"0.60"},{"v":0.057497,"d":"0.06"},{"v":0.156066,"d":"0.16"},{"v":0.1663,"d":"0.17"},{"v":0.061884,"d":"0.06"},{"v":0.153595,"d":"0.15"},{"v":2.12391985939509,"d":"2.12"},{"v":1.08672933081508,"d":"1.09"},{"v":0.350757486885679,"d":"0.35"},1,"up","no"]
[184896,0,"chr7","-",143379692,143380495,"ENST00000429630",2,648,"ENSG00000232533","AC093673","NA","NA","NA","NA","novel transcript",{"v":6.25369,"d":"6.25"},{"v":5.893084,"d":"5.89"},{"v":5.612487,"d":"5.61"},{"v":9.695472,"d":"9.70"},{"v":11.436719,"d":"11.44"},{"v":10.297083,"d":"10.30"},{"v":0.565054763912141,"d":"0.57"},{"v":-0.823537397632605,"d":"-0.82"},{"v":0.363093175279761,"d":"0.36"},1,"down","no"]
[182354,0,"chr7","+",101816008,102283958,"ENST00000622516",23,2928,"ENSG00000257923","CUX1","GO:0000122(negative regulation of transcription by RNA polymerase II);GO:0000139(Golgi membrane);GO:0000301(retrograde transport, vesicle recycling within Golgi);GO:0000977(RNA polymerase II regulatory region sequence-specific DNA binding);GO:0000981(DNA-binding transcription factor activity, RNA polymerase II-specific);GO:0003677(DNA binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005794(Golgi apparatus);GO:0005829(cytosol);GO:0006355(regulation of transcription, DNA-templated);GO:0006357(regulation of transcription by RNA polymerase II);GO:0006891(intra-Golgi vesicle-mediated transport);GO:0007275(multicellular organism development);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0030173(integral component of Golgi membrane);GO:0030674(protein binding, bridging);GO:0043565(sequence-specific DNA binding);GO:0048193(Golgi vesicle transport);GO:0050775(positive regulation of dendrite morphogenesis)","NA","NA","NA","cut like homeobox 1 [Source:HGNC Symbol;Acc:HGNC:2557]",{"v":1.495921,"d":"1.50"},{"v":0.245871,"d":"0.25"},{"v":0.184612,"d":"0.18"},{"v":1.485174,"d":"1.49"},{"v":1.056369,"d":"1.06"},{"v":1.304301,"d":"1.30"},{"v":0.500905392938455,"d":"0.50"},{"v":-0.997389950603024,"d":"-1.00"},{"v":0.368346901480028,"d":"0.37"},1,"down","no"]
[182606,0,"chr7","-",104167994,104207957,"ENST00000447452",9,1409,"ENSG00000164815","ORC5","GO:0000082(G1/S transition of mitotic cell cycle);GO:0000166(nucleotide binding);GO:0000784(nuclear chromosome, telomeric region);GO:0000808(origin recognition complex);GO:0003674(molecular_function);GO:0003688(DNA replication origin binding);GO:0005515(protein binding);GO:0005524(ATP binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005664(nuclear origin of replication recognition complex);GO:0005829(cytosol);GO:0006260(DNA replication);GO:0006270(DNA replication initiation)","04110(Cell cycle)","K02607","NA","origin recognition complex subunit 5 [Source:HGNC Symbol;Acc:HGNC:8491]",{"v":1.564962,"d":"1.56"},{"v":1.545391,"d":"1.55"},{"v":2.132369,"d":"2.13"},{"v":1.109306,"d":"1.11"},{"v":0.319953,"d":"0.32"},{"v":1.289706,"d":"1.29"},{"v":1.92820503390077,"d":"1.93"},{"v":0.947258467368917,"d":"0.95"},{"v":0.373812310066737,"d":"0.37"},1,"up","no"]
[36971,0,"chr11","+",118607643,118658025,"ENST00000356063",21,5240,"ENSG00000019144","PHLDB1","GO:0005515(protein binding);GO:0010470(regulation of gastrulation);GO:0010717(regulation of epithelial to mesenchymal transition);GO:0045180(basal cortex);GO:0070507(regulation of microtubule cytoskeleton organization);GO:1904261(positive regulation of basement membrane assembly involved in embryonic body morphogenesis)","NA","NA","NA","pleckstrin homology like domain family B member 1 [Source:HGNC Symbol;Acc:HGNC:23697]",{"v":15.788584,"d":"15.79"},{"v":7.364546,"d":"7.36"},{"v":1.698874,"d":"1.70"},{"v":4.844531,"d":"4.84"},{"v":7.84711,"d":"7.85"},{"v":1.62649,"d":"1.63"},{"v":1.73570167782373,"d":"1.74"},{"v":0.795519007166932,"d":"0.80"},{"v":0.378260878347866,"d":"0.38"},1,"up","no"]
[170294,0,"chr6","+",37354015,37391168,"ENST00000229866",8,2124,"ENSG00000112130","RNF8","GO:0000151(ubiquitin ligase complex);GO:0000781(chromosome, telomeric region);GO:0003682(chromatin binding);GO:0004842(ubiquitin-protein transferase activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005694(chromosome);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0006281(DNA repair);GO:0006302(double-strand break repair);GO:0006303(double-strand break repair via nonhomologous end joining);GO:0006325(chromatin organization);GO:0006511(ubiquitin-dependent protein catabolic process);GO:0006974(cellular response to DNA damage stimulus);GO:0007049(cell cycle);GO:0007286(spermatid development);GO:0008270(zinc ion binding);GO:0010212(response to ionizing radiation);GO:0016567(protein ubiquitination);GO:0016740(transferase activity);GO:0030496(midbody);GO:0031625(ubiquitin protein ligase binding);GO:0033522(histone H2A ubiquitination);GO:0033523(histone H2B ubiquitination);GO:0034244(negative regulation of transcription elongation from RNA polymerase II promoter);GO:0035093(spermatogenesis, exchange of chromosomal proteins);GO:0035861(site of double-strand break);GO:0036297(interstrand cross-link repair);GO:0042393(histone binding);GO:0042802(identical protein binding);GO:0042803(protein homodimerization activity);GO:0043130(ubiquitin binding);GO:0043486(histone exchange);GO:0045190(isotype switching);GO:0045739(positive regulation of DNA repair);GO:0046872(metal ion binding);GO:0051301(cell division);GO:0051865(protein autoubiquitination);GO:0070534(protein K63-linked ubiquitination);GO:0070535(histone H2A K63-linked ubiquitination);GO:0070936(protein K48-linked ubiquitination)","NA","K10667","EC:2.3.2.27","ring finger protein 8 [Source:HGNC Symbol;Acc:HGNC:10071]",{"v":5.828226,"d":"5.83"},{"v":1.95466,"d":"1.95"},{"v":5.397533,"d":"5.40"},{"v":1.106725,"d":"1.11"},{"v":4.775269,"d":"4.78"},{"v":1.175396,"d":"1.18"},{"v":1.86760530451059,"d":"1.87"},{"v":0.901189591347621,"d":"0.90"},{"v":0.38271056203961,"d":"0.38"},1,"up","no"]
[18284,0,"chr1","+",246789094,246792385,"ENST00000426089",2,2545,"ENSG00000227953","LINC01341","NA","NA","NA","NA","long intergenic non-protein coding RNA 1341 [Source:HGNC Symbol;Acc:HGNC:49457]",{"v":0.201702,"d":"0.20"},{"v":0.242904,"d":"0.24"},{"v":0.14891,"d":"0.15"},{"v":0.444146,"d":"0.44"},{"v":0.384534,"d":"0.38"},{"v":0.317996,"d":"0.32"},{"v":0.517596949792269,"d":"0.52"},{"v":-0.950098979358591,"d":"-0.95"},{"v":0.393522538326516,"d":"0.39"},1,"down","no"]
[81297,0,"chr17","-",8224821,8248095,"ENST00000315684",23,7072,"ENSG00000178971","CTC1","GO:0000723(telomere maintenance);GO:0000781(chromosome, telomeric region);GO:0000784(nuclear chromosome, telomeric region);GO:0003677(DNA binding);GO:0003697(single-stranded DNA binding);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005694(chromosome);GO:0006974(cellular response to DNA damage stimulus);GO:0007568(aging);GO:0010389(regulation of G2/M transition of mitotic cell cycle);GO:0010833(telomere maintenance via telomere lengthening);GO:0016233(telomere capping);GO:0032211(negative regulation of telomere maintenance via telomerase);GO:0035264(multicellular organism growth);GO:0042162(telomeric DNA binding);GO:0045740(positive regulation of DNA replication);GO:0048146(positive regulation of fibroblast proliferation);GO:0048536(spleen development);GO:0048538(thymus development);GO:0048539(bone marrow development);GO:0051276(chromosome organization);GO:0071425(hematopoietic stem cell proliferation);GO:0090399(replicative senescence);GO:0098505(G-rich strand telomeric DNA binding);GO:1990879(CST complex)","NA","NA","NA","CST telomere replication complex component 1 [Source:HGNC Symbol;Acc:HGNC:26169]",{"v":0.546718,"d":"0.55"},0,{"v":0.013658,"d":"0.01"},{"v":0.226677,"d":"0.23"},{"v":0.616956,"d":"0.62"},{"v":0.585361,"d":"0.59"},{"v":0.392147202857395,"d":"0.39"},{"v":-1.35053278501565,"d":"-1.35"},{"v":0.397741515062562,"d":"0.40"},1,"down","no"]
[16719,0,"chr1","-",222522264,222548104,"ENST00000343410",9,2572,"ENSG00000143512","HHIPL2","GO:0003824(catalytic activity);GO:0005515(protein binding);GO:0005576(extracellular region)","NA","NA","NA","HHIP like 2 [Source:HGNC Symbol;Acc:HGNC:25842]",{"v":1.714983,"d":"1.71"},{"v":1.125499,"d":"1.13"},{"v":1.416237,"d":"1.42"},{"v":0.84806,"d":"0.85"},{"v":0.510074,"d":"0.51"},{"v":0.983162,"d":"0.98"},{"v":1.81810373400031,"d":"1.82"},{"v":0.862434516505799,"d":"0.86"},{"v":0.401669085073183,"d":"0.40"},1,"up","no"]
[33173,0,"chr11","+",67606940,67612528,"ENST00000529927",10,1503,"ENSG00000167792","NDUFV1","GO:0003954(NADH dehydrogenase activity);GO:0005515(protein binding);GO:0005739(mitochondrion);GO:0005743(mitochondrial inner membrane);GO:0005747(mitochondrial respiratory chain complex I);GO:0005829(cytosol);GO:0006120(mitochondrial electron transport, NADH to ubiquinone);GO:0008137(NADH dehydrogenase (ubiquinone) activity);GO:0010181(FMN binding);GO:0016020(membrane);GO:0016491(oxidoreductase activity);GO:0016651(oxidoreductase activity, acting on NAD(P)H);GO:0032981(mitochondrial respiratory chain complex I assembly);GO:0042775(mitochondrial ATP synthesis coupled electron transport);GO:0045333(cellular respiration);GO:0046872(metal ion binding);GO:0051287(NAD binding);GO:0051536(iron-sulfur cluster binding);GO:0051539(4 iron, 4 sulfur cluster binding);GO:0055114(oxidation-reduction process);GO:0070469(respirasome)","00190(Oxidative phosphorylation);04714(Thermogenesis);04723(Retrograde endocannabinoid signaling);04932(Non-alcoholic fatty liver disease (NAFLD));05010(Alzheimer disease);05012(Parkinson disease);05016(Huntington disease)","K03942","1.6.99.3;EC:7.1.1.2","NADH:ubiquinone oxidoreductase core subunit V1 [Source:HGNC Symbol;Acc:HGNC:7716]",{"v":0.609958,"d":"0.61"},{"v":0.904706,"d":"0.90"},0,{"v":0.745961,"d":"0.75"},{"v":1.15597,"d":"1.16"},{"v":1.404889,"d":"1.40"},{"v":0.458042469804828,"d":"0.46"},{"v":-1.12644672334201,"d":"-1.13"},{"v":0.406847992436595,"d":"0.41"},1,"down","no"]
[17617,0,"chr1","+",234373701,234384046,"ENST00000366612",2,1013,"ENSG00000168275","COA6","GO:0003723(RNA binding);GO:0005507(copper ion binding);GO:0005515(protein binding);GO:0005739(mitochondrion);GO:0005758(mitochondrial intermembrane space);GO:0005886(plasma membrane);GO:0008535(respiratory chain complex IV assembly);GO:0042774(plasma membrane ATP synthesis coupled electron transport)","04714(Thermogenesis)","K18179","NA","cytochrome c oxidase assembly factor 6 [Source:HGNC Symbol;Acc:HGNC:18025]",{"v":0.680037,"d":"0.68"},{"v":1.192413,"d":"1.19"},{"v":1.267132,"d":"1.27"},{"v":0.770477,"d":"0.77"},{"v":0.515095,"d":"0.52"},{"v":0.297878,"d":"0.30"},{"v":1.98274779753071,"d":"1.98"},{"v":0.987501180647232,"d":"0.99"},{"v":0.410984396122196,"d":"0.41"},1,"up","no"]
[129800,0,"chr21","-",32578823,32612281,"ENST00000553001",7,929,"ENSG00000265590","C21orf59-TCP10L","GO:0003352(regulation of cilium movement)","NA","NA","NA","C21orf59-TCP10L readthrough [Source:NCBI gene;Acc:110091775]",{"v":0.679969,"d":"0.68"},{"v":1.021545,"d":"1.02"},{"v":3.525963,"d":"3.53"},{"v":1.128995,"d":"1.13"},{"v":1.176481,"d":"1.18"},{"v":0.474989,"d":"0.47"},{"v":1.88007293744032,"d":"1.88"},{"v":0.910788632350939,"d":"0.91"},{"v":0.420609266667249,"d":"0.42"},1,"up","no"]
[1150,0,"chr1","-",6590724,6603001,"ENST00000377663",3,6445,"ENSG00000162413","KLHL21","GO:0004842(ubiquitin-protein transferase activity);GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0005819(spindle);GO:0005827(polar microtubule);GO:0005829(cytosol);GO:0005856(cytoskeleton);GO:0007049(cell cycle);GO:0016567(protein ubiquitination);GO:0031463(Cul3-RING ubiquitin ligase complex);GO:0032465(regulation of cytokinesis);GO:0035853(chromosome passenger complex localization to spindle midzone);GO:0043687(post-translational protein modification);GO:0051301(cell division)","NA","K10458","NA","kelch like family member 21 [Source:HGNC Symbol;Acc:HGNC:29041]",{"v":1.314862,"d":"1.31"},{"v":1.221615,"d":"1.22"},{"v":0.913549,"d":"0.91"},{"v":1.200046,"d":"1.20"},{"v":2.504725,"d":"2.50"},{"v":1.785831,"d":"1.79"},{"v":0.628351135267135,"d":"0.63"},{"v":-0.670357103384567,"d":"-0.67"},{"v":0.42521757521172,"d":"0.43"},1,"down","no"]
[118628,0,"chr2","-",162267074,162318684,"ENST00000649979",16,3581,"ENSG00000115267","IFIH1","GO:0000166(nucleotide binding);GO:0002376(immune system process);GO:0003677(DNA binding);GO:0003723(RNA binding);GO:0003725(double-stranded RNA binding);GO:0003727(single-stranded RNA binding);GO:0004386(helicase activity);GO:0005515(protein binding);GO:0005524(ATP binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0008270(zinc ion binding);GO:0009597(detection of virus);GO:0009615(response to virus);GO:0016032(viral process);GO:0016579(protein deubiquitination);GO:0016787(hydrolase activity);GO:0016925(protein sumoylation);GO:0032480(negative regulation of type I interferon production);GO:0032727(positive regulation of interferon-alpha production);GO:0032728(positive regulation of interferon-beta production);GO:0034344(regulation of type III interferon production);GO:0035549(positive regulation of interferon-beta secretion);GO:0039528(cytoplasmic pattern recognition receptor signaling pathway in response to virus);GO:0039530(MDA-5 signaling pathway);GO:0042802(identical protein binding);GO:0043021(ribonucleoprotein complex binding);GO:0045087(innate immune response);GO:0046872(metal ion binding);GO:0051607(defense response to virus);GO:0060760(positive regulation of response to cytokine stimulus);GO:0071360(cellular response to exogenous dsRNA);GO:1902741(positive regulation of interferon-alpha secretion);GO:1904469(positive regulation of tumor necrosis factor secretion);GO:2000778(positive regulation of interleukin-6 secretion)","04622(RIG-I-like receptor signaling pathway);05161(Hepatitis B);05162(Measles);05164(Influenza A);05168(Herpes simplex virus 1 infection)","K12647","EC:3.6.4.13","interferon induced with helicase C domain 1 [Source:HGNC Symbol;Acc:HGNC:18873]",{"v":0.417959,"d":"0.42"},{"v":0.930507,"d":"0.93"},{"v":0.101374,"d":"0.10"},{"v":0.407347,"d":"0.41"},{"v":0.167358,"d":"0.17"},{"v":0.194583,"d":"0.19"},{"v":1.88465178190743,"d":"1.88"},{"v":0.914297988256311,"d":"0.91"},{"v":0.429450465690009,"d":"0.43"},1,"up","no"]
[33921,0,"chr11","-",72685075,72722358,"ENST00000334211",33,4942,"ENSG00000186635","ARAP1","GO:0001921(positive regulation of receptor recycling);GO:0005096(GTPase activator activity);GO:0005515(protein binding);GO:0005547(phosphatidylinositol-3,4,5-trisphosphate binding);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0005794(Golgi apparatus);GO:0005802(trans-Golgi network);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0007165(signal transduction);GO:0008360(regulation of cell shape);GO:0016020(membrane);GO:0030037(actin filament reorganization involved in cell cycle);GO:0031410(cytoplasmic vesicle);GO:0031702(type 1 angiotensin receptor binding);GO:0032580(Golgi cisterna membrane);GO:0043231(intracellular membrane-bounded organelle);GO:0043547(positive regulation of GTPase activity);GO:0045742(positive regulation of epidermal growth factor receptor signaling pathway);GO:0046872(metal ion binding);GO:0051056(regulation of small GTPase mediated signal transduction);GO:0051270(regulation of cellular component movement);GO:0051491(positive regulation of filopodium assembly);GO:0051497(negative regulation of stress fiber assembly)","04144(Endocytosis)","K18439","NA","ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1 [Source:HGNC Symbol;Acc:HGNC:16925]",{"v":7.665783,"d":"7.67"},{"v":7.95099,"d":"7.95"},{"v":8.068408,"d":"8.07"},{"v":5.202626,"d":"5.20"},{"v":6.688673,"d":"6.69"},{"v":4.152987,"d":"4.15"},{"v":1.47623777087993,"d":"1.48"},{"v":0.561925108419071,"d":"0.56"},{"v":0.433476383877427,"d":"0.43"},1,"up","no"]
[157244,0,"chr5","-",1317868,1331844,"ENST00000503042",8,3540,"ENSG00000049656","CLPTM1L","GO:0006915(apoptotic process);GO:0016020(membrane);GO:0016021(integral component of membrane)","NA","NA","NA","CLPTM1 like [Source:HGNC Symbol;Acc:HGNC:24308]",{"v":1.412633,"d":"1.41"},{"v":0.352101,"d":"0.35"},{"v":2.19298,"d":"2.19"},{"v":2.267403,"d":"2.27"},{"v":2.158041,"d":"2.16"},{"v":2.187433,"d":"2.19"},{"v":0.598485953995515,"d":"0.60"},{"v":-0.740610706262953,"d":"-0.74"},{"v":0.437933046106993,"d":"0.44"},1,"down","no"]
[41368,0,"chr12","+",30926428,30955260,"ENST00000545802",2,1649,"ENSG00000110900","TSPAN11","GO:0005887(integral component of plasma membrane);GO:0007166(cell surface receptor signaling pathway);GO:0016020(membrane);GO:0016021(integral component of membrane)","NA","K17352","NA","tetraspanin 11 [Source:HGNC Symbol;Acc:HGNC:30795]",{"v":0.820786,"d":"0.82"},{"v":0.932269,"d":"0.93"},{"v":0.586901,"d":"0.59"},{"v":0.489765,"d":"0.49"},{"v":0.483493,"d":"0.48"},{"v":0.348784,"d":"0.35"},{"v":1.76995587129607,"d":"1.77"},{"v":0.823713391350106,"d":"0.82"},{"v":0.447791481969821,"d":"0.45"},1,"up","no"]
[9111,0,"chr1","+",109494099,109500433,"ENST00000310611",4,5009,"ENSG00000174151","CYB561D1","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0046872(metal ion binding);GO:0055114(oxidation-reduction process)","NA","NA","NA","cytochrome b561 family member D1 [Source:HGNC Symbol;Acc:HGNC:26804]",{"v":1.993012,"d":"1.99"},{"v":1.264323,"d":"1.26"},{"v":2.352388,"d":"2.35"},{"v":1.820736,"d":"1.82"},{"v":3.347802,"d":"3.35"},{"v":3.398207,"d":"3.40"},{"v":0.654825490895317,"d":"0.65"},{"v":-0.610817611083151,"d":"-0.61"},{"v":0.452372891346608,"d":"0.45"},1,"down","no"]
[125175,0,"chr20","-",16272104,16573433,"ENST00000354981",26,5261,"ENSG00000089177","KIF16B","GO:0000166(nucleotide binding);GO:0001704(formation of primary germ layer);GO:0001919(regulation of receptor recycling);GO:0003774(motor activity);GO:0003777(microtubule motor activity);GO:0005515(protein binding);GO:0005524(ATP binding);GO:0005547(phosphatidylinositol-3,4,5-trisphosphate binding);GO:0005737(cytoplasm);GO:0005768(endosome);GO:0005769(early endosome);GO:0005829(cytosol);GO:0005856(cytoskeleton);GO:0005871(kinesin complex);GO:0005874(microtubule);GO:0006895(Golgi to endosome transport);GO:0007018(microtubule-based movement);GO:0007173(epidermal growth factor receptor signaling pathway);GO:0007492(endoderm development);GO:0008017(microtubule binding);GO:0008289(lipid binding);GO:0008543(fibroblast growth factor receptor signaling pathway);GO:0008574(ATP-dependent microtubule motor activity, plus-end-directed);GO:0016020(membrane);GO:0016887(ATPase activity);GO:0017137(Rab GTPase binding);GO:0031901(early endosome membrane);GO:0032266(phosphatidylinositol-3-phosphate binding);GO:0032801(receptor catabolic process);GO:0035091(phosphatidylinositol binding);GO:0043325(phosphatidylinositol-3,4-bisphosphate binding);GO:0045022(early endosome to late endosome transport);GO:0045335(phagocytic vesicle);GO:0071346(cellular response to interferon-gamma);GO:0080025(phosphatidylinositol-3,5-bisphosphate binding)","NA","K17916","NA","kinesin family member 16B [Source:HGNC Symbol;Acc:HGNC:15869]",{"v":7.453255,"d":"7.45"},{"v":7.967173,"d":"7.97"},{"v":7.647314,"d":"7.65"},{"v":5.099732,"d":"5.10"},{"v":5.156219,"d":"5.16"},{"v":5.750378,"d":"5.75"},{"v":1.44116380464253,"d":"1.44"},{"v":0.527234323517312,"d":"0.53"},{"v":0.455869353816221,"d":"0.46"},1,"up","no"]
[56489,0,"chr14","-",50462693,50483149,"ENST00000557210",9,1084,"ENSG00000012983","MAP4K5","GO:0000166(nucleotide binding);GO:0000185(activation of MAPKKK activity);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005515(protein binding);GO:0005524(ATP binding);GO:0005737(cytoplasm);GO:0006468(protein phosphorylation);GO:0007257(activation of JUN kinase activity);GO:0008349(MAP kinase kinase kinase kinase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0016740(transferase activity);GO:0023014(signal transduction by protein phosphorylation);GO:0031098(stress-activated protein kinase signaling cascade);GO:0032147(activation of protein kinase activity);GO:0035556(intracellular signal transduction)","NA","K08833","EC:2.7.11.1","mitogen-activated protein kinase kinase kinase kinase 5 [Source:HGNC Symbol;Acc:HGNC:6867]",{"v":1.364159,"d":"1.36"},{"v":2.078408,"d":"2.08"},{"v":1.880307,"d":"1.88"},{"v":2.461302,"d":"2.46"},{"v":0.086225,"d":"0.09"},{"v":0.058243,"d":"0.06"},{"v":2.0427259504868,"d":"2.04"},{"v":1.03049566692302,"d":"1.03"},{"v":0.459752877134908,"d":"0.46"},1,"up","no"]
[161601,0,"chr5","-",111499882,111512562,"ENST00000505803",6,803,"ENSG00000164211","STARD4","GO:0006869(lipid transport);GO:0008289(lipid binding);GO:0010873(positive regulation of cholesterol esterification);GO:0010879(cholesterol transport involved in cholesterol storage);GO:0015485(cholesterol binding);GO:0017127(cholesterol transporter activity);GO:0031410(cytoplasmic vesicle);GO:0032367(intracellular cholesterol transport);GO:0070508(cholesterol import);GO:0070859(positive regulation of bile acid biosynthetic process)","NA","NA","NA","StAR related lipid transfer domain containing 4 [Source:HGNC Symbol;Acc:HGNC:18058]",{"v":0.772371,"d":"0.77"},{"v":0.415482,"d":"0.42"},{"v":0.453455,"d":"0.45"},{"v":0.401137,"d":"0.40"},{"v":1.221026,"d":"1.22"},{"v":1.436072,"d":"1.44"},{"v":0.536684721743097,"d":"0.54"},{"v":-0.897853276609079,"d":"-0.90"},{"v":0.463517601625346,"d":"0.46"},1,"down","no"]
[8378,0,"chr1","+",93448282,93554661,"ENST00000370253",15,3889,"ENSG00000137942","FNBP1L","GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005856(cytoskeleton);GO:0005886(plasma membrane);GO:0005938(cell cortex);GO:0006897(endocytosis);GO:0006900(vesicle budding from membrane);GO:0006914(autophagy);GO:0008289(lipid binding);GO:0010324(membrane invagination);GO:0016020(membrane);GO:0016050(vesicle organization);GO:0030050(vesicle transport along actin filament);GO:0031410(cytoplasmic vesicle);GO:0045296(cadherin binding);GO:0051020(GTPase binding);GO:0051491(positive regulation of filopodium assembly);GO:0060271(cilium assembly);GO:0061024(membrane organization);GO:0072583(clathrin-dependent endocytosis);GO:0097320(plasma membrane tubulation)","NA","K20121","NA","formin binding protein 1 like [Source:HGNC Symbol;Acc:HGNC:20851]",{"v":3.040214,"d":"3.04"},{"v":3.216122,"d":"3.22"},{"v":3.792748,"d":"3.79"},{"v":1.905102,"d":"1.91"},{"v":2.365192,"d":"2.37"},{"v":2.264567,"d":"2.26"},{"v":1.53776553166165,"d":"1.54"},{"v":0.620835547450601,"d":"0.62"},{"v":0.472068245992969,"d":"0.47"},1,"up","no"]
[80420,0,"chr17","+",5486396,5490737,"ENST00000573759",2,2204,"ENSG00000167842","MIS12","GO:0000070(mitotic sister chromatid segregation);GO:0000278(mitotic cell cycle);GO:0000444(MIS12/MIND type complex);GO:0000775(chromosome, centromeric region);GO:0000776(kinetochore);GO:0000777(condensed chromosome kinetochore);GO:0000818(nuclear MIS12/MIND complex);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005694(chromosome);GO:0005829(cytosol);GO:0007049(cell cycle);GO:0007059(chromosome segregation);GO:0034501(protein localization to kinetochore);GO:0051301(cell division);GO:0051315(attachment of mitotic spindle microtubules to kinetochore);GO:0051382(kinetochore assembly)","NA","K11543","NA","MIS12, kinetochore complex component [Source:HGNC Symbol;Acc:HGNC:24967]",{"v":1.981854,"d":"1.98"},{"v":2.338147,"d":"2.34"},{"v":2.252429,"d":"2.25"},{"v":1.950671,"d":"1.95"},{"v":0.511017,"d":"0.51"},{"v":1.465567,"d":"1.47"},{"v":1.67354297085369,"d":"1.67"},{"v":0.742905594969239,"d":"0.74"},{"v":0.476251828290147,"d":"0.48"},1,"up","no"]
[207473,0,"chrX","-",154506171,154516239,"ENST00000447601",9,1800,"ENSG00000071889","FAM3A","GO:0003674(molecular_function);GO:0005515(protein binding);GO:0005575(cellular_component);GO:0005576(extracellular region);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0019732(antifungal humoral response);GO:0045721(negative regulation of gluconeogenesis);GO:0046890(regulation of lipid biosynthetic process);GO:0061844(antimicrobial humoral immune response mediated by antimicrobial peptide);GO:1905035(negative regulation of antifungal innate immune response)","NA","NA","NA","family with sequence similarity 3 member A [Source:HGNC Symbol;Acc:HGNC:13749]",{"v":2.081887,"d":"2.08"},{"v":1.400345,"d":"1.40"},{"v":1.785726,"d":"1.79"},{"v":0.157201,"d":"0.16"},{"v":0.221513,"d":"0.22"},{"v":2.512977,"d":"2.51"},{"v":1.8217568889622,"d":"1.82"},{"v":0.86533044624746,"d":"0.87"},{"v":0.48021821418089,"d":"0.48"},1,"up","no"]
[135552,0,"chr22","+",45502883,45601135,"ENST00000327858",17,2904,"ENSG00000077942","FBLN1","GO:0001933(negative regulation of protein phosphorylation);GO:0001968(fibronectin binding);GO:0005201(extracellular matrix structural constituent);GO:0005509(calcium ion binding);GO:0005576(extracellular region);GO:0005604(basement membrane);GO:0005615(extracellular space);GO:0007162(negative regulation of cell adhesion);GO:0007566(embryo implantation);GO:0008022(protein C-terminus binding);GO:0010952(positive regulation of peptidase activity);GO:0016032(viral process);GO:0016504(peptidase activator activity);GO:0030198(extracellular matrix organization);GO:0031012(extracellular matrix);GO:0042802(identical protein binding);GO:0044877(protein-containing complex binding);GO:0062023(collagen-containing extracellular matrix);GO:0070051(fibrinogen binding);GO:0070062(extracellular exosome);GO:0070373(negative regulation of ERK1 and ERK2 cascade);GO:0071953(elastic fiber);GO:0072378(blood coagulation, fibrin clot formation);GO:1900025(negative regulation of substrate adhesion-dependent cell spreading);GO:2000146(negative regulation of cell motility);GO:2000647(negative regulation of stem cell proliferation)","NA","K17307","NA","fibulin 1 [Source:HGNC Symbol;Acc:HGNC:3600]",{"v":535.138123,"d":"535.14"},{"v":553.600403,"d":"553.60"},{"v":635.644165,"d":"635.64"},{"v":399.52298,"d":"399.52"},{"v":462.131409,"d":"462.13"},{"v":397.801361,"d":"397.80"},{"v":1.36914908761185,"d":"1.37"},{"v":0.453279551232271,"d":"0.45"},{"v":0.483236283160427,"d":"0.48"},1,"up","no"]
[42111,0,"chr12","-",47841537,47905022,"ENST00000549336",10,4644,"ENSG00000111424","VDR","GO:0000122(negative regulation of transcription by RNA polymerase II);GO:0000902(cell morphogenesis);GO:0000976(transcription regulatory region sequence-specific DNA binding);GO:0000977(RNA polymerase II regulatory region sequence-specific DNA binding);GO:0000981(DNA-binding transcription factor activity, RNA polymerase II-specific);GO:0001501(skeletal system development);GO:0003677(DNA binding);GO:0003700(DNA-binding transcription factor activity);GO:0003707(steroid hormone receptor activity);GO:0004879(nuclear receptor activity);GO:0005499(vitamin D binding);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0006355(regulation of transcription, DNA-templated);GO:0006367(transcription initiation from RNA polymerase II promoter);GO:0006816(calcium ion transport);GO:0006874(cellular calcium ion homeostasis);GO:0007165(signal transduction);GO:0007275(multicellular organism development);GO:0007595(lactation);GO:0008134(transcription factor binding);GO:0008270(zinc ion binding);GO:0008285(negative regulation of cell population proliferation);GO:0009887(animal organ morphogenesis);GO:0010628(positive regulation of gene expression);GO:0010839(negative regulation of keratinocyte proliferation);GO:0010980(positive regulation of vitamin D 24-hydroxylase activity);GO:0030154(cell differentiation);GO:0030374(nuclear receptor transcription coactivator activity);GO:0030522(intracellular receptor signaling pathway);GO:0038023(signaling receptor activity);GO:0038183(bile acid signaling pathway);GO:0038186(lithocholic acid receptor activity);GO:0042359(vitamin D metabolic process);GO:0043235(receptor complex);GO:0043401(steroid hormone mediated signaling pathway);GO:0043565(sequence-specific DNA binding);GO:0045618(positive regulation of keratinocyte differentiation);GO:0045892(negative regulation of transcription, DNA-templated);GO:0045944(positive regulation of transcription by RNA polymerase II);GO:0046697(decidualization);GO:0046872(metal ion binding);GO:0046965(retinoid X receptor binding);GO:0050892(intestinal absorption);GO:0060058(positive regulation of apoptotic process involved in mammary gland involution);GO:0060558(regulation of calcidiol 1-monooxygenase activity);GO:0060745(mammary gland branching involved in pregnancy);GO:0070561(vitamin D receptor signaling pathway);GO:0070644(vitamin D response element binding);GO:0090575(RNA polymerase II transcription factor complex);GO:1902098(calcitriol binding);GO:1902121(lithocholic acid binding)","04928(Parathyroid hormone synthesis, secretion and action);04961(Endocrine and other factor-regulated calcium reabsorption);04978(Mineral absorption);05152(Tuberculosis)","K08539","NA","vitamin D receptor [Source:HGNC Symbol;Acc:HGNC:12679]",{"v":0.47958,"d":"0.48"},{"v":1.234113,"d":"1.23"},{"v":0.028041,"d":"0.03"},{"v":1.521948,"d":"1.52"},{"v":1.109676,"d":"1.11"},{"v":0.431971,"d":"0.43"},{"v":0.568526192267581,"d":"0.57"},{"v":-0.814701278603449,"d":"-0.81"},{"v":0.486807956324925,"d":"0.49"},1,"down","no"]
[166898,0,"chr6","-",3153666,3157544,"ENST00000333628",4,1616,"ENSG00000137267","TUBB2A","GO:0000166(nucleotide binding);GO:0000226(microtubule cytoskeleton organization);GO:0000278(mitotic cell cycle);GO:0003924(GTPase activity);GO:0005200(structural constituent of cytoskeleton);GO:0005515(protein binding);GO:0005525(GTP binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005856(cytoskeleton);GO:0005874(microtubule);GO:0007017(microtubule-based process);GO:0070062(extracellular exosome);GO:1903561(extracellular vesicle)","04145(Phagosome);04540(Gap junction);05130(Pathogenic Escherichia coli infection)","K07375","NA","tubulin beta 2A class IIa [Source:HGNC Symbol;Acc:HGNC:12412]",{"v":17.617847,"d":"17.62"},{"v":13.402295,"d":"13.40"},{"v":14.095594,"d":"14.10"},{"v":21.248695,"d":"21.25"},{"v":22.576151,"d":"22.58"},{"v":17.762802,"d":"17.76"},{"v":0.732545201271528,"d":"0.73"},{"v":-0.449010311955467,"d":"-0.45"},{"v":0.495008479707236,"d":"0.50"},1,"down","no"]
[121331,0,"chr2","-",206176566,206213371,"ENST00000442134",3,830,"ENSG00000183671","GPR1","GO:0004930(G protein-coupled receptor activity);GO:0005515(protein binding);GO:0005654(nucleoplasm);GO:0005886(plasma membrane);GO:0005887(integral component of plasma membrane);GO:0007165(signal transduction);GO:0007186(G protein-coupled receptor signaling pathway);GO:0007218(neuropeptide signaling pathway);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0042277(peptide binding);GO:0042923(neuropeptide binding);GO:0043231(intracellular membrane-bounded organelle)","NA","K04310","NA","G protein-coupled receptor 1 [Source:HGNC Symbol;Acc:HGNC:4463]",{"v":1.669301,"d":"1.67"},{"v":0.434498,"d":"0.43"},{"v":1.544126,"d":"1.54"},{"v":1.045326,"d":"1.05"},{"v":1.914017,"d":"1.91"},{"v":2.949708,"d":"2.95"},{"v":0.617345323301491,"d":"0.62"},{"v":-0.695850382091221,"d":"-0.70"},{"v":0.49855981910989,"d":"0.50"},1,"down","no"]
[158855,0,"chr5","+",50667557,50843374,"ENST00000505554",26,3825,"ENSG00000151883","PARP8","GO:0003950(NAD+ ADP-ribosyltransferase activity);GO:0005622(intracellular);GO:0006471(protein ADP-ribosylation);GO:0016740(transferase activity);GO:0016757(transferase activity, transferring glycosyl groups);GO:0070213(protein auto-ADP-ribosylation);GO:0140289(protein mono-ADP-ribosylation);GO:1990404(protein ADP-ribosylase activity)","NA","K15258","EC:2.4.2.30","poly(ADP-ribose) polymerase family member 8 [Source:HGNC Symbol;Acc:HGNC:26124]",{"v":0.525787,"d":"0.53"},{"v":2.401068,"d":"2.40"},{"v":0.578211,"d":"0.58"},{"v":1.045037,"d":"1.05"},{"v":0.009438,"d":"0.01"},{"v":0.80034,"d":"0.80"},{"v":1.88971191196966,"d":"1.89"},{"v":0.918166311244157,"d":"0.92"},{"v":0.502178831503998,"d":"0.50"},1,"up","no"]
[128918,0,"chr21","+",5582228,5592004,"ENST00000624444",2,7628,"ENSG00000274333","CU633967","NA","NA","NA","NA","uncharacterized LOC102724219 [Source:NCBI gene;Acc:102724219]",{"v":1.730423,"d":"1.73"},{"v":0.539763,"d":"0.54"},{"v":0.033718,"d":"0.03"},{"v":1.511019,"d":"1.51"},{"v":1.221674,"d":"1.22"},{"v":1.134543,"d":"1.13"},{"v":0.595749522397909,"d":"0.60"},{"v":-0.747222205055021,"d":"-0.75"},{"v":0.505826985241608,"d":"0.51"},1,"down","no"]
[19151,0,"chr10","-",12167672,12195860,"ENST00000378952",11,917,"ENSG00000165609","NUDT5","GO:0000287(magnesium ion binding);GO:0003723(RNA binding);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005829(cytosol);GO:0006139(nucleobase-containing compound metabolic process);GO:0006338(chromatin remodeling);GO:0006753(nucleoside phosphate metabolic process);GO:0009117(nucleotide metabolic process);GO:0009191(ribonucleoside diphosphate catabolic process);GO:0016740(transferase activity);GO:0016779(nucleotidyltransferase activity);GO:0016787(hydrolase activity);GO:0017110(nucleoside-diphosphatase activity);GO:0019144(ADP-sugar diphosphatase activity);GO:0019303(D-ribose catabolic process);GO:0019693(ribose phosphate metabolic process);GO:0030515(snoRNA binding);GO:0034656(nucleobase-containing small molecule catabolic process);GO:0042803(protein homodimerization activity);GO:0044715(8-oxo-dGDP phosphatase activity);GO:0046872(metal ion binding);GO:0047631(ADP-ribose diphosphatase activity);GO:0070062(extracellular exosome);GO:1990966(ATP generation from poly-ADP-D-ribose)","00230(Purine metabolism)","K13987","2.7.7.96;3.6.1.58;EC:3.6.1.13","nudix hydrolase 5 [Source:HGNC Symbol;Acc:HGNC:8052]",{"v":2.823793,"d":"2.82"},{"v":2.540445,"d":"2.54"},{"v":1.999008,"d":"2.00"},{"v":1.70467,"d":"1.70"},{"v":4.165691,"d":"4.17"},{"v":5.689628,"d":"5.69"},{"v":0.63695960264322,"d":"0.64"},{"v":-0.650726218346772,"d":"-0.65"},{"v":0.509678650205044,"d":"0.51"},1,"down","no"]
[206066,0,"chrX","-",130623385,130903317,"ENST00000338144",16,4263,"ENSG00000165675","ENOX2","GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0005576(extracellular region);GO:0005615(extracellular space);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0007624(ultradian rhythm);GO:0009897(external side of plasma membrane);GO:0015035(protein disulfide oxidoreductase activity);GO:0016020(membrane);GO:0016491(oxidoreductase activity);GO:0040008(regulation of growth);GO:0048511(rhythmic process);GO:0055114(oxidation-reduction process)","NA","NA","NA","ecto-NOX disulfide-thiol exchanger 2 [Source:HGNC Symbol;Acc:HGNC:2259]",{"v":0.003754,"d":"0.00"},0,{"v":0.358428,"d":"0.36"},{"v":0.3123,"d":"0.31"},{"v":0.021293,"d":"0.02"},{"v":0.467584,"d":"0.47"},{"v":0.452062403189308,"d":"0.45"},{"v":-1.14540615729639,"d":"-1.15"},{"v":0.513021391062564,"d":"0.51"},1,"down","no"]
[133372,0,"chr22","+",29603999,29694806,"ENST00000361166",17,1837,"ENSG00000186575","NF2","GO:0001707(mesoderm formation);GO:0001726(ruffle);GO:0001953(negative regulation of cell-matrix adhesion);GO:0003779(actin binding);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005730(nucleolus);GO:0005737(cytoplasm);GO:0005769(early endosome);GO:0005829(cytosol);GO:0005856(cytoskeleton);GO:0005886(plasma membrane);GO:0005912(adherens junction);GO:0006469(negative regulation of protein kinase activity);GO:0007398(ectoderm development);GO:0007420(brain development);GO:0008092(cytoskeletal protein binding);GO:0008285(negative regulation of cell population proliferation);GO:0014010(Schwann cell proliferation);GO:0014013(regulation of gliogenesis);GO:0016020(membrane);GO:0021766(hippocampus development);GO:0022408(negative regulation of cell-cell adhesion);GO:0030027(lamellipodium);GO:0030036(actin cytoskeleton organization);GO:0030175(filopodium);GO:0030336(negative regulation of cell migration);GO:0030864(cortical actin cytoskeleton);GO:0031527(filopodium membrane);GO:0031647(regulation of protein stability);GO:0032154(cleavage furrow);GO:0032587(ruffle membrane);GO:0035330(regulation of hippo signaling);GO:0042127(regulation of cell population proliferation);GO:0042475(odontogenesis of dentin-containing tooth);GO:0042532(negative regulation of tyrosine phosphorylation of STAT protein);GO:0042981(regulation of apoptotic process);GO:0042995(cell projection);GO:0043005(neuron projection);GO:0043409(negative regulation of MAPK cascade);GO:0044297(cell body);GO:0045177(apical part of cell);GO:0045216(cell-cell junction organization);GO:0045597(positive regulation of cell differentiation);GO:0046426(negative regulation of receptor signaling pathway via JAK-STAT);GO:0048471(perinuclear region of cytoplasm);GO:0050767(regulation of neurogenesis);GO:0051496(positive regulation of stress fiber assembly);GO:0051726(regulation of cell cycle);GO:0070306(lens fiber cell differentiation);GO:0072091(regulation of stem cell proliferation);GO:1900180(regulation of protein localization to nucleus);GO:2000177(regulation of neural precursor cell proliferation)","04390(Hippo signaling pathway);04392(Hippo signaling pathway - multiple species);04530(Tight junction)","K16684","NA","neurofibromin 2 [Source:HGNC Symbol;Acc:HGNC:7773]",{"v":0.925206,"d":"0.93"},{"v":0.648917,"d":"0.65"},{"v":0.294157,"d":"0.29"},{"v":0.390484,"d":"0.39"},{"v":0.365378,"d":"0.37"},{"v":0.349099,"d":"0.35"},{"v":1.69081080689726,"d":"1.69"},{"v":0.757715238564413,"d":"0.76"},{"v":0.520497662843747,"d":"0.52"},1,"up","no"]
[21593,0,"chr10","+",68901289,68946847,"ENST00000610822",16,2523,"ENSG00000107625","DDX50","GO:0000166(nucleotide binding);GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0004386(helicase activity);GO:0005524(ATP binding);GO:0005634(nucleus);GO:0005730(nucleolus);GO:0005886(plasma membrane);GO:0016020(membrane);GO:0016787(hydrolase activity)","NA","K13183","EC:3.6.4.13","DExD-box helicase 50 [Source:HGNC Symbol;Acc:HGNC:17906]",{"v":4.485571,"d":"4.49"},{"v":0.468265,"d":"0.47"},{"v":4.173269,"d":"4.17"},{"v":4.28683,"d":"4.29"},{"v":6.920326,"d":"6.92"},{"v":2.731501,"d":"2.73"},{"v":0.654805193929372,"d":"0.65"},{"v":-0.610862329540737,"d":"-0.61"},{"v":0.52366943962123,"d":"0.52"},1,"down","no"]
[73906,0,"chr16","+",30748551,30756517,"ENST00000565897",7,1068,"ENSG00000156873","PHKG2","GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0004683(calmodulin-dependent protein kinase activity);GO:0004689(phosphorylase kinase activity);GO:0005515(protein binding);GO:0005516(calmodulin binding);GO:0005524(ATP binding);GO:0005829(cytosol);GO:0005964(phosphorylase kinase complex);GO:0005975(carbohydrate metabolic process);GO:0005977(glycogen metabolic process);GO:0005978(glycogen biosynthetic process);GO:0005980(glycogen catabolic process);GO:0006091(generation of precursor metabolites and energy);GO:0006468(protein phosphorylation);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0016740(transferase activity);GO:0019899(enzyme binding);GO:0045819(positive regulation of glycogen catabolic process);GO:0050321(tau-protein kinase activity)","04020(Calcium signaling pathway);04910(Insulin signaling pathway);04922(Glucagon signaling pathway)","K00871","EC:2.7.11.19","phosphorylase kinase catalytic subunit gamma 2 [Source:HGNC Symbol;Acc:HGNC:8931]",{"v":0.87631,"d":"0.88"},{"v":0.101539,"d":"0.10"},{"v":0.242757,"d":"0.24"},{"v":0.65584,"d":"0.66"},{"v":0.806609,"d":"0.81"},{"v":0.684786,"d":"0.68"},{"v":0.568454780217349,"d":"0.57"},{"v":-0.814882505577968,"d":"-0.81"},{"v":0.526630168228208,"d":"0.53"},1,"down","no"]
[46580,0,"chr12","-",94308280,94459946,"ENST00000339839",16,3130,"ENSG00000173588","CEP83","GO:0003674(molecular_function);GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0005794(Golgi apparatus);GO:0005814(centriole);GO:0005829(cytosol);GO:0005856(cytoskeleton);GO:0030030(cell projection organization);GO:0048278(vesicle docking);GO:0051660(establishment of centrosome localization);GO:0060271(cilium assembly);GO:0071539(protein localization to centrosome);GO:0097539(ciliary transition fiber);GO:0097711(ciliary basal body-plasma membrane docking)","NA","K16754","NA","centrosomal protein 83 [Source:HGNC Symbol;Acc:HGNC:17966]",{"v":0.237081,"d":"0.24"},{"v":0.480278,"d":"0.48"},{"v":0.513786,"d":"0.51"},{"v":0.795673,"d":"0.80"},{"v":0.338908,"d":"0.34"},{"v":0.741246,"d":"0.74"},{"v":0.656321185269217,"d":"0.66"},{"v":-0.607526092550332,"d":"-0.61"},{"v":0.529874585060573,"d":"0.53"},1,"down","no"]
[136197,0,"chr3","+",3126965,3150879,"ENST00000434583",10,1871,"ENSG00000072756","TRNT1","GO:0000049(tRNA binding);GO:0000166(nucleotide binding);GO:0001680(tRNA 3'-terminal CCA addition);GO:0003723(RNA binding);GO:0005524(ATP binding);GO:0005622(intracellular);GO:0005654(nucleoplasm);GO:0005739(mitochondrion);GO:0005759(mitochondrial matrix);GO:0006396(RNA processing);GO:0008033(tRNA processing);GO:0016740(transferase activity);GO:0016779(nucleotidyltransferase activity);GO:0034062(5'-3' RNA polymerase activity);GO:0042780(tRNA 3'-end processing);GO:0052927(CTP:tRNA cytidylyltransferase activity);GO:0052928(CTP:3'-cytidine-tRNA cytidylyltransferase activity);GO:0052929(ATP:3'-cytidine-cytidine-tRNA adenylyltransferase activity);GO:1990180(mitochondrial tRNA 3'-end processing)","03013(RNA transport)","K00974","3.1.3.-;3.1.4.-;EC:2.7.7.72","tRNA nucleotidyl transferase 1 [Source:HGNC Symbol;Acc:HGNC:17341]",{"v":1.440584,"d":"1.44"},{"v":2.29615,"d":"2.30"},{"v":0.554519,"d":"0.55"},{"v":0.376284,"d":"0.38"},{"v":1.848379,"d":"1.85"},{"v":0.393093,"d":"0.39"},{"v":1.6392868548482,"d":"1.64"},{"v":0.713068330249483,"d":"0.71"},{"v":0.533108651047091,"d":"0.53"},1,"up","no"]
[117206,0,"chr2","-",130338243,130342349,"ENST00000442217",6,1847,"ENSG00000136710","CCDC115","GO:0005764(lysosome);GO:0005768(endosome);GO:0005783(endoplasmic reticulum);GO:0005793(endoplasmic reticulum-Golgi intermediate compartment);GO:0006879(cellular iron ion homeostasis);GO:0007042(lysosomal lumen acidification);GO:0016020(membrane);GO:0016471(vacuolar proton-transporting V-type ATPase complex);GO:0030137(COPI-coated vesicle);GO:0031410(cytoplasmic vesicle);GO:0036295(cellular response to increased oxygen levels);GO:0042406(extrinsic component of endoplasmic reticulum membrane);GO:0051082(unfolded protein binding);GO:0070072(vacuolar proton-transporting V-type ATPase complex assembly);GO:1905146(lysosomal protein catabolic process)","NA","NA","NA","coiled-coil domain containing 115 [Source:HGNC Symbol;Acc:HGNC:28178]",{"v":1.237042,"d":"1.24"},{"v":1.174819,"d":"1.17"},{"v":1.31266,"d":"1.31"},{"v":0.835878,"d":"0.84"},{"v":0.844564,"d":"0.84"},{"v":0.727998,"d":"0.73"},{"v":1.54644541695039,"d":"1.55"},{"v":0.628955913230162,"d":"0.63"},{"v":0.541041344629514,"d":"0.54"},1,"up","no"]
[35952,0,"chr11","+",108009260,108106852,"ENST00000531427",20,3596,"ENSG00000166266","CUL5","GO:0000082(G1/S transition of mitotic cell cycle);GO:0004842(ubiquitin-protein transferase activity);GO:0005262(calcium channel activity);GO:0005515(protein binding);GO:0005829(cytosol);GO:0006511(ubiquitin-dependent protein catabolic process);GO:0007050(cell cycle arrest);GO:0008283(cell population proliferation);GO:0008285(negative regulation of cell population proliferation);GO:0016032(viral process);GO:0016567(protein ubiquitination);GO:0019005(SCF ubiquitin ligase complex);GO:0031146(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process);GO:0031461(cullin-RING ubiquitin ligase complex);GO:0031466(Cul5-RING ubiquitin ligase complex);GO:0031625(ubiquitin protein ligase binding);GO:0038023(signaling receptor activity);GO:0038128(ERBB2 signaling pathway);GO:0043161(proteasome-mediated ubiquitin-dependent protein catabolic process);GO:0043687(post-translational protein modification);GO:0061630(ubiquitin protein ligase activity);GO:0070588(calcium ion transmembrane transport);GO:0097193(intrinsic apoptotic signaling pathway)","04120(Ubiquitin mediated proteolysis);05170(Human immunodeficiency virus 1 infection)","K10612","NA","cullin 5 [Source:HGNC Symbol;Acc:HGNC:2556]",0,{"v":0.611572,"d":"0.61"},{"v":0.345722,"d":"0.35"},0,0,{"v":0.3615,"d":"0.36"},{"v":2.64811618257261,"d":"2.65"},{"v":1.40496641985825,"d":"1.40"},{"v":0.544328750747114,"d":"0.54"},1,"up","no"]
[24950,0,"chr10","+",122393105,122432354,"ENST00000368988",12,3872,"ENSG00000107679","PLEKHA1","GO:0001553(luteinization);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0006661(phosphatidylinositol biosynthetic process);GO:0007283(spermatogenesis);GO:0008209(androgen metabolic process);GO:0008210(estrogen metabolic process);GO:0008289(lipid binding);GO:0008585(female gonad development);GO:0009791(post-embryonic development);GO:0014065(phosphatidylinositol 3-kinase signaling);GO:0016020(membrane);GO:0030165(PDZ domain binding);GO:0031529(ruffle organization);GO:0032587(ruffle membrane);GO:0033327(Leydig cell differentiation);GO:0035264(multicellular organism growth);GO:0043325(phosphatidylinositol-3,4-bisphosphate binding);GO:0045184(establishment of protein localization);GO:0048008(platelet-derived growth factor receptor signaling pathway);GO:0048705(skeletal system morphogenesis);GO:0050853(B cell receptor signaling pathway);GO:0051898(negative regulation of protein kinase B signaling);GO:0060021(roof of mouth development);GO:0060325(face morphogenesis);GO:0070062(extracellular exosome);GO:0070301(cellular response to hydrogen peroxide)","NA","NA","NA","pleckstrin homology domain containing A1 [Source:HGNC Symbol;Acc:HGNC:14335]",{"v":0.486149,"d":"0.49"},{"v":0.093921,"d":"0.09"},{"v":1.322014,"d":"1.32"},{"v":1.127407,"d":"1.13"},{"v":0.55183,"d":"0.55"},{"v":1.307085,"d":"1.31"},{"v":0.636931985231331,"d":"0.64"},{"v":-0.650788772340471,"d":"-0.65"},{"v":0.547334414563326,"d":"0.55"},1,"down","no"]
[71794,0,"chr16","+",14975105,15037687,"ENST00000570001",22,4828,"ENSG00000179889","PDXDC1","GO:0001667(ameboidal-type cell migration);GO:0003824(catalytic activity);GO:0005783(endoplasmic reticulum);GO:0005794(Golgi apparatus);GO:0006665(sphingolipid metabolic process);GO:0008117(sphinganine-1-phosphate aldolase activity);GO:0016829(lyase activity);GO:0016831(carboxy-lyase activity);GO:0019752(carboxylic acid metabolic process);GO:0030149(sphingolipid catabolic process);GO:0030170(pyridoxal phosphate binding);GO:0043231(intracellular membrane-bounded organelle);GO:0045296(cadherin binding)","NA","NA","NA","pyridoxal dependent decarboxylase domain containing 1 [Source:HGNC Symbol;Acc:HGNC:28995]",{"v":7.594946,"d":"7.59"},{"v":8.173338,"d":"8.17"},{"v":7.381484,"d":"7.38"},{"v":6.457942,"d":"6.46"},{"v":0.570718,"d":"0.57"},{"v":8.803209,"d":"8.80"},{"v":1.46222584332905,"d":"1.46"},{"v":0.548166155262696,"d":"0.55"},{"v":0.550298518084593,"d":"0.55"},1,"up","no"]
[178465,0,"chr7","+",43758680,43807342,"ENST00000265523",8,1074,"ENSG00000106605","BLVRA","GO:0004074(biliverdin reductase activity);GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0008270(zinc ion binding);GO:0016491(oxidoreductase activity);GO:0042167(heme catabolic process);GO:0046872(metal ion binding);GO:0055114(oxidation-reduction process);GO:0070062(extracellular exosome)","00860(Porphyrin and chlorophyll metabolism)","NA","NA","biliverdin reductase A [Source:HGNC Symbol;Acc:HGNC:1062]",{"v":23.042994,"d":"23.04"},{"v":21.044024,"d":"21.04"},{"v":19.129507,"d":"19.13"},{"v":27.915606,"d":"27.92"},{"v":26.953018,"d":"26.95"},{"v":27.888079,"d":"27.89"},{"v":0.763884044534737,"d":"0.76"},{"v":-0.388574437085776,"d":"-0.39"},{"v":0.55289200671586,"d":"0.55"},1,"down","no"]
[53176,0,"chr13","+",102799119,102841533,"ENST00000257336",11,3789,"ENSG00000134897","BIVM","GO:0005615(extracellular space);GO:0005634(nucleus);GO:0005737(cytoplasm)","NA","NA","NA","basic, immunoglobulin-like variable motif containing [Source:HGNC Symbol;Acc:HGNC:16034]",{"v":9.919815,"d":"9.92"},{"v":10.358546,"d":"10.36"},{"v":5.488415,"d":"5.49"},{"v":6.864104,"d":"6.86"},{"v":8.089027,"d":"8.09"},{"v":3.937948,"d":"3.94"},{"v":1.36396528753069,"d":"1.36"},{"v":0.447806928713569,"d":"0.45"},{"v":0.560334939644794,"d":"0.56"},1,"up","no"]
[116050,0,"chr2","+",108448561,108509398,"ENST00000309863",23,7537,"ENSG00000135968","GCC2","GO:0005515(protein binding);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0005794(Golgi apparatus);GO:0005802(trans-Golgi network);GO:0005829(cytosol);GO:0006622(protein targeting to lysosome);GO:0015031(protein transport);GO:0016020(membrane);GO:0031023(microtubule organizing center organization);GO:0034067(protein localization to Golgi apparatus);GO:0034453(microtubule anchoring);GO:0034499(late endosome to Golgi transport);GO:0042147(retrograde transport, endosome to Golgi);GO:0042802(identical protein binding);GO:0070861(regulation of protein exit from endoplasmic reticulum);GO:0071955(recycling endosome to Golgi transport);GO:0090161(Golgi ribbon formation)","NA","K20282","NA","GRIP and coiled-coil domain containing 2 [Source:HGNC Symbol;Acc:HGNC:23218]",{"v":2.527473,"d":"2.53"},{"v":2.629291,"d":"2.63"},{"v":0.974435,"d":"0.97"},{"v":2.616247,"d":"2.62"},{"v":3.14857,"d":"3.15"},{"v":2.497453,"d":"2.50"},{"v":0.742071972956585,"d":"0.74"},{"v":-0.430368975437588,"d":"-0.43"},{"v":0.563968511522759,"d":"0.56"},1,"down","no"]
[27657,0,"chr11","-",11965935,12009211,"ENST00000533813",7,903,"ENSG00000050165","DKK3","GO:0005576(extracellular region);GO:0005615(extracellular space);GO:0007275(multicellular organism development);GO:0009653(anatomical structure morphogenesis);GO:0016055(Wnt signaling pathway);GO:0017015(regulation of transforming growth factor beta receptor signaling pathway);GO:0030178(negative regulation of Wnt signaling pathway);GO:0030325(adrenal gland development);GO:0032348(negative regulation of aldosterone biosynthetic process);GO:0039706(co-receptor binding);GO:0045892(negative regulation of transcription, DNA-templated);GO:0048019(receptor antagonist activity);GO:0090090(negative regulation of canonical Wnt signaling pathway);GO:1902613(negative regulation of anti-Mullerian hormone signaling pathway);GO:2000065(negative regulation of cortisol biosynthetic process);GO:2000272(negative regulation of signaling receptor activity)","NA","NA","NA","dickkopf WNT signaling pathway inhibitor 3 [Source:HGNC Symbol;Acc:HGNC:2893]",{"v":5.604179,"d":"5.60"},{"v":4.883893,"d":"4.88"},{"v":2.707185,"d":"2.71"},{"v":6.258668,"d":"6.26"},{"v":6.149887,"d":"6.15"},{"v":6.535425,"d":"6.54"},{"v":0.696540906398761,"d":"0.70"},{"v":-0.52172001309361,"d":"-0.52"},{"v":0.566556586687098,"d":"0.57"},1,"down","no"]
[180814,0,"chr7","+",87345681,87399481,"ENST00000419147",19,2959,"ENSG00000005469","CROT","GO:0005102(signaling receptor binding);GO:0005777(peroxisome);GO:0005782(peroxisomal matrix);GO:0005829(cytosol);GO:0006091(generation of precursor metabolites and energy);GO:0006625(protein targeting to peroxisome);GO:0006629(lipid metabolic process);GO:0006631(fatty acid metabolic process);GO:0006635(fatty acid beta-oxidation);GO:0008458(carnitine O-octanoyltransferase activity);GO:0009437(carnitine metabolic process);GO:0015908(fatty acid transport);GO:0015936(coenzyme A metabolic process);GO:0016740(transferase activity);GO:0016746(transferase activity, transferring acyl groups);GO:0033540(fatty acid beta-oxidation using acyl-CoA oxidase);GO:0043231(intracellular membrane-bounded organelle);GO:0051791(medium-chain fatty acid metabolic process)","04146(Peroxisome)","K05940","EC:2.3.1.137","carnitine O-octanoyltransferase [Source:HGNC Symbol;Acc:HGNC:2366]",{"v":0.681173,"d":"0.68"},{"v":0.333427,"d":"0.33"},{"v":0.725876,"d":"0.73"},{"v":0.787933,"d":"0.79"},{"v":0.571744,"d":"0.57"},{"v":1.192205,"d":"1.19"},{"v":0.682036238352714,"d":"0.68"},{"v":-0.552079699475428,"d":"-0.55"},{"v":0.569637659812024,"d":"0.57"},1,"down","no"]
[205370,0,"chrX","-",108084830,108091542,"ENST00000361815",5,768,"ENSG00000101843","PSMD10","GO:0000122(negative regulation of transcription by RNA polymerase II);GO:0000165(MAPK cascade);GO:0000209(protein polyubiquitination);GO:0000502(proteasome complex);GO:0002223(stimulatory C-type lectin receptor signaling pathway);GO:0002479(antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0006521(regulation of cellular amino acid metabolic process);GO:0006915(apoptotic process);GO:0007253(cytoplasmic sequestering of NF-kappaB);GO:0008134(transcription factor binding);GO:0008540(proteasome regulatory particle, base subcomplex);GO:0010972(negative regulation of G2/M transition of mitotic cell cycle);GO:0016579(protein deubiquitination);GO:0030307(positive regulation of cell growth);GO:0031145(anaphase-promoting complex-dependent catabolic process);GO:0031146(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process);GO:0031398(positive regulation of protein ubiquitination);GO:0032088(negative regulation of NF-kappaB transcription factor activity);GO:0032436(positive regulation of proteasomal ubiquitin-dependent protein catabolic process);GO:0033209(tumor necrosis factor-mediated signaling pathway);GO:0038061(NIK/NF-kappaB signaling);GO:0038095(Fc-epsilon receptor signaling pathway);GO:0043066(negative regulation of apoptotic process);GO:0043161(proteasome-mediated ubiquitin-dependent protein catabolic process);GO:0043409(negative regulation of MAPK cascade);GO:0043488(regulation of mRNA stability);GO:0043518(negative regulation of DNA damage response, signal transduction by p53 class mediator);GO:0043687(post-translational protein modification);GO:0045111(intermediate filament cytoskeleton);GO:0045737(positive regulation of cyclin-dependent protein serine/threonine kinase activity);GO:0050852(T cell receptor signaling pathway);GO:0055085(transmembrane transport);GO:0060071(Wnt signaling pathway, planar cell polarity pathway);GO:0061418(regulation of transcription from RNA polymerase II promoter in response to hypoxia);GO:0070498(interleukin-1-mediated signaling pathway);GO:0070682(proteasome regulatory particle assembly);GO:0090090(negative regulation of canonical Wnt signaling pathway);GO:0090201(negative regulation of release of cytochrome c from mitochondria);GO:0090263(positive regulation of canonical Wnt signaling pathway);GO:1901990(regulation of mitotic cell cycle phase transition);GO:1902036(regulation of hematopoietic stem cell differentiation)","NA","NA","NA","proteasome 26S subunit, non-ATPase 10 [Source:HGNC Symbol;Acc:HGNC:9555]",{"v":0.714043,"d":"0.71"},{"v":1.355061,"d":"1.36"},{"v":1.182743,"d":"1.18"},{"v":0.666976,"d":"0.67"},{"v":1.184737,"d":"1.18"},{"v":0.05064,"d":"0.05"},{"v":1.70938148703211,"d":"1.71"},{"v":0.773474402883652,"d":"0.77"},{"v":0.572740239610971,"d":"0.57"},1,"up","no"]
[27611,0,"chr11","-",10852706,10858053,"ENST00000413761",3,2687,"ENSG00000236287","ZBED5","GO:0000981(DNA-binding transcription factor activity, RNA polymerase II-specific);GO:0003677(DNA binding);GO:0005654(nucleoplasm);GO:0006357(regulation of transcription by RNA polymerase II);GO:0046872(metal ion binding)","NA","NA","NA","zinc finger BED-type containing 5 [Source:HGNC Symbol;Acc:HGNC:30803]",{"v":16.341545,"d":"16.34"},{"v":19.599518,"d":"19.60"},{"v":19.169327,"d":"19.17"},{"v":14.44421,"d":"14.44"},{"v":11.291236,"d":"11.29"},{"v":16.123678,"d":"16.12"},{"v":1.31656816325158,"d":"1.32"},{"v":0.396782216590439,"d":"0.40"},{"v":0.579282715847706,"d":"0.58"},1,"up","no"]
[62750,0,"chr15","-",39600031,39782841,"ENST00000350221",12,2816,"ENSG00000150667","FSIP1","NA","NA","NA","NA","fibrous sheath interacting protein 1 [Source:HGNC Symbol;Acc:HGNC:21674]",{"v":0.322485,"d":"0.32"},{"v":0.400717,"d":"0.40"},{"v":0.455515,"d":"0.46"},{"v":0.153821,"d":"0.15"},{"v":0.181346,"d":"0.18"},{"v":0.415655,"d":"0.42"},{"v":1.56990205401547,"d":"1.57"},{"v":0.650674552369063,"d":"0.65"},{"v":0.581845330129924,"d":"0.58"},1,"up","no"]
[183053,0,"chr7","-",113083609,113086338,"ENST00000449591",2,1630,"ENSG00000164604","GPR85","GO:0004930(G protein-coupled receptor activity);GO:0005515(protein binding);GO:0005783(endoplasmic reticulum);GO:0005886(plasma membrane);GO:0007165(signal transduction);GO:0007186(G protein-coupled receptor signaling pathway);GO:0016020(membrane);GO:0016021(integral component of membrane)","NA","K04302","NA","G protein-coupled receptor 85 [Source:HGNC Symbol;Acc:HGNC:4536]",{"v":0.313648,"d":"0.31"},{"v":0.186056,"d":"0.19"},{"v":0.56626,"d":"0.57"},{"v":0.893089,"d":"0.89"},{"v":0.547029,"d":"0.55"},{"v":0.20139,"d":"0.20"},{"v":0.649380935091392,"d":"0.65"},{"v":-0.622863065133784,"d":"-0.62"},{"v":0.584656261199082,"d":"0.58"},1,"down","no"]
[39063,0,"chr12","+",6452231,6466517,"ENST00000545700",9,2344,"ENSG00000139192","TAPBPL","GO:0000139(Golgi membrane);GO:0002376(immune system process);GO:0002502(peptide antigen assembly with MHC class I protein complex);GO:0002590(negative regulation of antigen processing and presentation of peptide antigen via MHC class I);GO:0005515(protein binding);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005794(Golgi apparatus);GO:0005886(plasma membrane);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0023024(MHC class I protein complex binding);GO:0031090(organelle membrane);GO:0043231(intracellular membrane-bounded organelle);GO:0044877(protein-containing complex binding)","NA","NA","NA","TAP binding protein like [Source:HGNC Symbol;Acc:HGNC:30683]",{"v":0.165128,"d":"0.17"},{"v":0.361634,"d":"0.36"},{"v":1.001514,"d":"1.00"},{"v":0.503001,"d":"0.50"},{"v":0.302743,"d":"0.30"},{"v":0.132281,"d":"0.13"},{"v":1.62924868740172,"d":"1.63"},{"v":0.704206832652767,"d":"0.70"},{"v":0.587375140708379,"d":"0.59"},1,"up","no"]
[120086,0,"chr2","-",187464230,187554435,"ENST00000233156",8,3859,"ENSG00000003436","TFPI","GO:0004866(endopeptidase inhibitor activity);GO:0004867(serine-type endopeptidase inhibitor activity);GO:0005576(extracellular region);GO:0005615(extracellular space);GO:0005783(endoplasmic reticulum);GO:0005886(plasma membrane);GO:0005901(caveola);GO:0007596(blood coagulation);GO:0007598(blood coagulation, extrinsic pathway);GO:0007599(hemostasis);GO:0009986(cell surface);GO:0010466(negative regulation of peptidase activity);GO:0010951(negative regulation of endopeptidase activity);GO:0016020(membrane);GO:0030195(negative regulation of blood coagulation);GO:0030414(peptidase inhibitor activity);GO:0031090(organelle membrane);GO:0031225(anchored component of membrane);GO:0032355(response to estradiol);GO:0032496(response to lipopolysaccharide);GO:0043231(intracellular membrane-bounded organelle);GO:0071222(cellular response to lipopolysaccharide);GO:0071347(cellular response to interleukin-1);GO:0071383(cellular response to steroid hormone stimulus)","04610(Complement and coagulation cascades)","K03909","NA","tissue factor pathway inhibitor [Source:HGNC Symbol;Acc:HGNC:11760]",{"v":2.636822,"d":"2.64"},{"v":3.212812,"d":"3.21"},{"v":2.109251,"d":"2.11"},{"v":3.995095,"d":"4.00"},{"v":3.507076,"d":"3.51"},{"v":3.104623,"d":"3.10"},{"v":0.750357271009506,"d":"0.75"},{"v":-0.414350418763597,"d":"-0.41"},{"v":0.590483121080489,"d":"0.59"},1,"down","no"]
[24886,0,"chr10","-",121740421,121928801,"ENST00000540606",12,5165,"ENSG00000107669","ATE1","GO:0004057(arginyltransferase activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0010498(proteasomal protein catabolic process);GO:0016598(protein arginylation);GO:0016740(transferase activity);GO:0016746(transferase activity, transferring acyl groups)","NA","K00685","EC:2.3.2.8","arginyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:782]",{"v":0.02224,"d":"0.02"},{"v":1.635495,"d":"1.64"},{"v":2.18749,"d":"2.19"},{"v":1.093801,"d":"1.09"},{"v":2.166582,"d":"2.17"},{"v":2.552571,"d":"2.55"},{"v":0.661492418484647,"d":"0.66"},{"v":-0.596203473345289,"d":"-0.60"},{"v":0.596939547326096,"d":"0.60"},1,"down","no"]
[36199,0,"chr11","+",111879541,111885975,"ENST00000260276",4,2568,"ENSG00000137720","C11orf1","GO:0003674(molecular_function);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0008150(biological_process)","NA","NA","NA","chromosome 11 open reading frame 1 [Source:HGNC Symbol;Acc:HGNC:1163]",{"v":1.632997,"d":"1.63"},{"v":2.506133,"d":"2.51"},{"v":1.613018,"d":"1.61"},{"v":1.070906,"d":"1.07"},{"v":1.557992,"d":"1.56"},{"v":1.365646,"d":"1.37"},{"v":1.4400011615844,"d":"1.44"},{"v":0.52606997542549,"d":"0.53"},{"v":0.599511162971371,"d":"0.60"},1,"up","no"]
[164756,0,"chr5","+",154858262,154870747,"ENST00000520472",5,912,"ENSG00000155508","CNOT8","GO:0000175(3'-5'-exoribonuclease activity);GO:0000289(nuclear-transcribed mRNA poly(A) tail shortening);GO:0000932(P-body);GO:0003676(nucleic acid binding);GO:0003700(DNA-binding transcription factor activity);GO:0003723(RNA binding);GO:0004518(nuclease activity);GO:0004527(exonuclease activity);GO:0004535(poly(A)-specific ribonuclease activity);GO:0005515(protein binding);GO:0005622(intracellular);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0006417(regulation of translation);GO:0006977(DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest);GO:0008284(positive regulation of cell population proliferation);GO:0016787(hydrolase activity);GO:0017148(negative regulation of translation);GO:0030014(CCR4-NOT complex);GO:0030015(CCR4-NOT core complex);GO:0031047(gene silencing by RNA);GO:0035195(gene silencing by miRNA);GO:0043928(exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay);GO:0046872(metal ion binding);GO:0061014(positive regulation of mRNA catabolic process);GO:0090305(nucleic acid phosphodiester bond hydrolysis);GO:0090503(RNA phosphodiester bond hydrolysis, exonucleolytic)","03018(RNA degradation)","K12581","NA","CCR4-NOT transcription complex subunit 8 [Source:HGNC Symbol;Acc:HGNC:9207]",{"v":0.270809,"d":"0.27"},{"v":0.335915,"d":"0.34"},{"v":1.140304,"d":"1.14"},{"v":1.863423,"d":"1.86"},{"v":0.170903,"d":"0.17"},{"v":0.701249,"d":"0.70"},{"v":0.638632828564379,"d":"0.64"},{"v":-0.646941379139222,"d":"-0.65"},{"v":0.602367533153999,"d":"0.60"},1,"down","no"]
[184558,0,"chr7","-",140719327,140924810,"ENST00000496384",19,9578,"ENSG00000157764","BRAF","GO:0000165(MAPK cascade);GO:0000166(nucleotide binding);GO:0000186(activation of MAPKK activity);GO:0002318(myeloid progenitor cell differentiation);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0004709(MAP kinase kinase kinase activity);GO:0004713(protein tyrosine kinase activity);GO:0005509(calcium ion binding);GO:0005515(protein binding);GO:0005524(ATP binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005739(mitochondrion);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0006468(protein phosphorylation);GO:0007165(signal transduction);GO:0008542(visual learning);GO:0009887(animal organ morphogenesis);GO:0010628(positive regulation of gene expression);GO:0010764(negative regulation of fibroblast migration);GO:0010828(positive regulation of glucose transmembrane transport);GO:0016020(membrane);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0016740(transferase activity);GO:0017016(Ras GTPase binding);GO:0018108(peptidyl-tyrosine phosphorylation);GO:0030154(cell differentiation);GO:0030878(thyroid gland development);GO:0031434(mitogen-activated protein kinase kinase binding);GO:0033138(positive regulation of peptidyl-serine phosphorylation);GO:0035019(somatic stem cell population maintenance);GO:0035556(intracellular signal transduction);GO:0035690(cellular response to drug);GO:0042127(regulation of cell population proliferation);GO:0042802(identical protein binding);GO:0043005(neuron projection);GO:0043066(negative regulation of apoptotic process);GO:0043231(intracellular membrane-bounded organelle);GO:0043367(CD4-positive, alpha-beta T cell differentiation);GO:0043368(positive T cell selection);GO:0043369(CD4-positive or CD8-positive, alpha-beta T cell lineage commitment);GO:0043434(response to peptide hormone);GO:0043524(negative regulation of neuron apoptotic process);GO:0044297(cell body);GO:0045580(regulation of T cell differentiation);GO:0046632(alpha-beta T cell differentiation);GO:0046872(metal ion binding);GO:0046982(protein heterodimerization activity);GO:0048538(thymus development);GO:0048679(regulation of axon regeneration);GO:0048680(positive regulation of axon regeneration);GO:0050772(positive regulation of axonogenesis);GO:0050852(T cell receptor signaling pathway);GO:0051291(protein heterooligomerization);GO:0051496(positive regulation of stress fiber assembly);GO:0051591(response to cAMP);GO:0060291(long-term synaptic potentiation);GO:0060323(head morphogenesis);GO:0060324(face development);GO:0070374(positive regulation of ERK1 and ERK2 cascade);GO:0070413(trehalose metabolism in response to stress);GO:0071277(cellular response to calcium ion);GO:0090150(establishment of protein localization to membrane);GO:1900026(positive regulation of substrate adhesion-dependent cell spreading);GO:1990090(cellular response to nerve growth factor stimulus);GO:2000301(negative regulation of synaptic vesicle exocytosis);GO:2000352(negative regulation of endothelial cell apoptotic process)","01521(EGFR tyrosine kinase inhibitor resistance);01522(Endocrine resistance);04010(MAPK signaling pathway);04012(ErbB signaling pathway);04015(Rap1 signaling pathway);04024(cAMP signaling pathway);04062(Chemokine signaling pathway);04068(FoxO signaling pathway);04150(mTOR signaling pathway);04270(Vascular smooth muscle contraction);04510(Focal adhesion);04650(Natural killer cell mediated cytotoxicity);04720(Long-term potentiation);04722(Neurotrophin signaling pathway);04726(Serotonergic synapse);04730(Long-term depression);04810(Regulation of actin cytoskeleton);04910(Insulin signaling pathway);04914(Progesterone-mediated oocyte maturation);04928(Parathyroid hormone synthesis, secretion and action);04934(Cushing syndrome);05034(Alcoholism);05160(Hepatitis C);05161(Hepatitis B);05200(Pathways in cancer);05205(Proteoglycans in cancer);05210(Colorectal cancer);05211(Renal cell carcinoma);05212(Pancreatic cancer);05213(Endometrial cancer);05214(Glioma);05215(Prostate cancer);05216(Thyroid cancer);05218(Melanoma);05219(Bladder cancer);05220(Chronic myeloid leukemia);05221(Acute myeloid leukemia);05223(Non-small cell lung cancer);05224(Breast cancer);05225(Hepatocellular carcinoma);05226(Gastric cancer)","NA","NA","B-Raf proto-oncogene, serine/threonine kinase [Source:HGNC Symbol;Acc:HGNC:1097]",{"v":3.108055,"d":"3.11"},{"v":2.593378,"d":"2.59"},{"v":3.242715,"d":"3.24"},{"v":2.107194,"d":"2.11"},{"v":2.020725,"d":"2.02"},{"v":2.71654,"d":"2.72"},{"v":1.30677209111779,"d":"1.31"},{"v":0.386007548413319,"d":"0.39"},{"v":0.605196964620483,"d":"0.61"},1,"up","no"]
[29602,0,"chr11","+",46277661,46321422,"ENST00000621158",12,2687,"ENSG00000157613","CREB3L1","GO:0000122(negative regulation of transcription by RNA polymerase II);GO:0000790(nuclear chromatin);GO:0000981(DNA-binding transcription factor activity, RNA polymerase II-specific);GO:0001227(DNA-binding transcription repressor activity, RNA polymerase II-specific);GO:0001228(DNA-binding transcription activator activity, RNA polymerase II-specific);GO:0001649(osteoblast differentiation);GO:0003677(DNA binding);GO:0003682(chromatin binding);GO:0003700(DNA-binding transcription factor activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0006355(regulation of transcription, DNA-templated);GO:0006986(response to unfolded protein);GO:0007275(multicellular organism development);GO:0010629(negative regulation of gene expression);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0030968(endoplasmic reticulum unfolded protein response);GO:0032967(positive regulation of collagen biosynthetic process);GO:0035497(cAMP response element binding);GO:0040037(negative regulation of fibroblast growth factor receptor signaling pathway);GO:0044212(transcription regulatory region DNA binding);GO:0045892(negative regulation of transcription, DNA-templated);GO:0045944(positive regulation of transcription by RNA polymerase II);GO:0046332(SMAD binding);GO:0070278(extracellular matrix constituent secretion);GO:1902236(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway);GO:1903671(negative regulation of sprouting angiogenesis);GO:1990440(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)","04022(cGMP-PKG signaling pathway);04024(cAMP signaling pathway);04151(PI3K-Akt signaling pathway);04152(AMPK signaling pathway);04211(Longevity regulating pathway);04261(Adrenergic signaling in cardiomyocytes);04668(TNF signaling pathway);04714(Thermogenesis);04725(Cholinergic synapse);04728(Dopaminergic synapse);04911(Insulin secretion);04915(Estrogen signaling pathway);04916(Melanogenesis);04918(Thyroid hormone synthesis);04922(Glucagon signaling pathway);04925(Aldosterone synthesis and secretion);04926(Relaxin signaling pathway);04927(Cortisol synthesis and secretion);04928(Parathyroid hormone synthesis, secretion and action);04931(Insulin resistance);04934(Cushing syndrome);04962(Vasopressin-regulated water reabsorption);05016(Huntington disease);05030(Cocaine addiction);05031(Amphetamine addiction);05034(Alcoholism);05161(Hepatitis B);05163(Human cytomegalovirus infection);05165(Human papillomavirus infection);05166(Human T-cell leukemia virus 1 infection);05203(Viral carcinogenesis);05215(Prostate cancer)","K09048","NA","cAMP responsive element binding protein 3 like 1 [Source:HGNC Symbol;Acc:HGNC:18856]",{"v":48.274723,"d":"48.27"},{"v":47.087795,"d":"47.09"},{"v":50.01487,"d":"50.01"},{"v":61.03231,"d":"61.03"},{"v":58.928921,"d":"58.93"},{"v":57.793919,"d":"57.79"},{"v":0.817851904712747,"d":"0.82"},{"v":-0.290088468932566,"d":"-0.29"},{"v":0.608734404217753,"d":"0.61"},1,"down","no"]
[9059,0,"chr1","+",109213918,109238182,"ENST00000234677",11,1914,"ENSG00000031698","SARS","GO:0000122(negative regulation of transcription by RNA polymerase II);GO:0000166(nucleotide binding);GO:0000978(RNA polymerase II proximal promoter sequence-specific DNA binding);GO:0003677(DNA binding);GO:0003723(RNA binding);GO:0004812(aminoacyl-tRNA ligase activity);GO:0004828(serine-tRNA ligase activity);GO:0005515(protein binding);GO:0005524(ATP binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0006412(translation);GO:0006418(tRNA aminoacylation for protein translation);GO:0006434(seryl-tRNA aminoacylation);GO:0008033(tRNA processing);GO:0016259(selenocysteine metabolic process);GO:0016525(negative regulation of angiogenesis);GO:0016874(ligase activity);GO:0042803(protein homodimerization activity);GO:0070062(extracellular exosome);GO:0097056(selenocysteinyl-tRNA(Sec) biosynthetic process);GO:1904046(negative regulation of vascular endothelial growth factor production)","00970(Aminoacyl-tRNA biosynthesis)","K01875","EC:6.1.1.11","seryl-tRNA synthetase [Source:HGNC Symbol;Acc:HGNC:10537]",{"v":75.814095,"d":"75.81"},{"v":82.208595,"d":"82.21"},{"v":77.669586,"d":"77.67"},{"v":92.934052,"d":"92.93"},{"v":102.313202,"d":"102.31"},{"v":92.425888,"d":"92.43"},{"v":0.819305807839371,"d":"0.82"},{"v":-0.287526053148128,"d":"-0.29"},{"v":0.61121270155617,"d":"0.61"},1,"down","no"]
[127279,0,"chr20","+",45418527,45426219,"ENST00000638962",10,2090,"ENSG00000124155","PIGT","GO:0003923(GPI-anchor transamidase activity);GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0006506(GPI anchor biosynthetic process);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016255(attachment of GPI anchor to protein);GO:0030176(integral component of endoplasmic reticulum membrane);GO:0030182(neuron differentiation);GO:0031410(cytoplasmic vesicle);GO:0042765(GPI-anchor transamidase complex);GO:0051402(neuron apoptotic process)","00563(Glycosylphosphatidylinositol (GPI)-anchor biosynthesis)","K05292","NA","phosphatidylinositol glycan anchor biosynthesis class T [Source:HGNC Symbol;Acc:HGNC:14938]",{"v":0.851353,"d":"0.85"},{"v":1.110098,"d":"1.11"},{"v":0.681951,"d":"0.68"},0,{"v":0.625592,"d":"0.63"},{"v":0.990491,"d":"0.99"},{"v":1.63568455333049,"d":"1.64"},{"v":0.709894547041274,"d":"0.71"},{"v":0.616816873096898,"d":"0.62"},1,"up","no"]
[189342,0,"chr8","+",55773142,55825446,"ENST00000260129",13,3782,"ENSG00000137574","TGS1","GO:0000387(spliceosomal snRNP assembly);GO:0001510(RNA methylation);GO:0005515(protein binding);GO:0005615(extracellular space);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005730(nucleolus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0008168(methyltransferase activity);GO:0008173(RNA methyltransferase activity);GO:0009452(7-methylguanosine RNA capping);GO:0015030(Cajal body);GO:0016740(transferase activity);GO:0019216(regulation of lipid metabolic process);GO:0022613(ribonucleoprotein complex biogenesis);GO:0030532(small nuclear ribonucleoprotein complex);GO:0032259(methylation);GO:0036261(7-methylguanosine cap hypermethylation);GO:0071164(RNA trimethylguanosine synthase activity)","03013(RNA transport)","K14292","EC:2.1.1.-","trimethylguanosine synthase 1 [Source:HGNC Symbol;Acc:HGNC:17843]",{"v":5.59748,"d":"5.60"},{"v":5.779926,"d":"5.78"},{"v":5.835546,"d":"5.84"},{"v":4.493738,"d":"4.49"},{"v":4.257975,"d":"4.26"},{"v":4.384479,"d":"4.38"},{"v":1.31034564659225,"d":"1.31"},{"v":0.389947420044756,"d":"0.39"},{"v":0.61980193584522,"d":"0.62"},1,"up","no"]
[204526,0,"chrX","-",77506905,77596875,"ENST00000623706",8,7245,"ENSG00000085224","ATRX","GO:0000166(nucleotide binding);GO:0000212(meiotic spindle organization);GO:0000228(nuclear chromosome);GO:0000780(condensed nuclear chromosome, centromeric region);GO:0000781(chromosome, telomeric region);GO:0000784(nuclear chromosome, telomeric region);GO:0000792(heterochromatin);GO:0000981(DNA-binding transcription factor activity, RNA polymerase II-specific);GO:0003677(DNA binding);GO:0003682(chromatin binding);GO:0004386(helicase activity);GO:0005515(protein binding);GO:0005524(ATP binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005694(chromosome);GO:0005720(nuclear heterochromatin);GO:0005721(pericentric heterochromatin);GO:0006281(DNA repair);GO:0006306(DNA methylation);GO:0006325(chromatin organization);GO:0006334(nucleosome assembly);GO:0006336(DNA replication-independent nucleosome assembly);GO:0006338(chromatin remodeling);GO:0006355(regulation of transcription, DNA-templated);GO:0006974(cellular response to DNA damage stimulus);GO:0007283(spermatogenesis);GO:0010571(positive regulation of nuclear cell cycle DNA replication);GO:0015616(DNA translocase activity);GO:0016604(nuclear body);GO:0016605(PML body);GO:0016787(hydrolase activity);GO:0030330(DNA damage response, signal transduction by p53 class mediator);GO:0030900(forebrain development);GO:0031297(replication fork processing);GO:0031618(nuclear pericentric heterochromatin);GO:0031933(telomeric heterochromatin);GO:0032206(positive regulation of telomere maintenance);GO:0035064(methylated histone binding);GO:0035128(post-embryonic forelimb morphogenesis);GO:0035264(multicellular organism growth);GO:0042393(histone binding);GO:0045944(positive regulation of transcription by RNA polymerase II);GO:0046872(metal ion binding);GO:0060009(Sertoli cell development);GO:0070087(chromo shadow domain binding);GO:0070192(chromosome organization involved in meiotic cell cycle);GO:0070198(protein localization to chromosome, telomeric region);GO:0072520(seminiferous tubule development);GO:0072711(cellular response to hydroxyurea);GO:1900112(regulation of histone H3-K9 trimethylation);GO:1901581(negative regulation of telomeric RNA transcription from RNA pol II promoter);GO:1901582(positive regulation of telomeric RNA transcription from RNA pol II promoter);GO:1904908(negative regulation of maintenance of mitotic sister chromatid cohesion, telomeric);GO:1990707(nuclear subtelomeric heterochromatin)","NA","NA","NA","ATRX, chromatin remodeler [Source:HGNC Symbol;Acc:HGNC:886]",{"v":0.68954,"d":"0.69"},{"v":0.444769,"d":"0.44"},{"v":0.595228,"d":"0.60"},{"v":0.503965,"d":"0.50"},{"v":0.371858,"d":"0.37"},{"v":0.343017,"d":"0.34"},{"v":1.41900249417479,"d":"1.42"},{"v":0.504877125219773,"d":"0.50"},{"v":0.621704140554747,"d":"0.62"},1,"up","no"]
[38963,0,"chr12","+",6199715,6238271,"ENST00000382518",9,1566,"ENSG00000010278","CD9","GO:0002576(platelet degranulation);GO:0005178(integrin binding);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0005615(extracellular space);GO:0005886(plasma membrane);GO:0005887(integral component of plasma membrane);GO:0005925(focal adhesion);GO:0007155(cell adhesion);GO:0007166(cell surface receptor signaling pathway);GO:0007338(single fertilization);GO:0007342(fusion of sperm to egg plasma membrane involved in single fertilization);GO:0007420(brain development);GO:0008285(negative regulation of cell population proliferation);GO:0009414(response to water deprivation);GO:0009897(external side of plasma membrane);GO:0009986(cell surface);GO:0014003(oligodendrocyte development);GO:0014905(myoblast fusion involved in skeletal muscle regeneration);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016324(apical plasma membrane);GO:0030168(platelet activation);GO:0030666(endocytic vesicle membrane);GO:0030669(clathrin-coated endocytic vesicle membrane);GO:0030913(paranodal junction assembly);GO:0031092(platelet alpha granule membrane);GO:0031623(receptor internalization);GO:0035036(sperm-egg recognition);GO:0051271(negative regulation of cellular component movement);GO:0070062(extracellular exosome);GO:0071404(cellular response to low-density lipoprotein particle stimulus);GO:0090331(negative regulation of platelet aggregation);GO:1903561(extracellular vesicle);GO:1905521(regulation of macrophage migration)","04640(Hematopoietic cell lineage)","NA","NA","CD9 molecule [Source:HGNC Symbol;Acc:HGNC:1709]",{"v":14.271372,"d":"14.27"},{"v":28.180319,"d":"28.18"},{"v":22.557514,"d":"22.56"},{"v":6.0281,"d":"6.03"},{"v":12.985613,"d":"12.99"},{"v":30.094297,"d":"30.09"},{"v":1.32380043500032,"d":"1.32"},{"v":0.404685649988155,"d":"0.40"},{"v":0.62486348734469,"d":"0.62"},1,"up","no"]
[44282,0,"chr12","+",56266891,56270469,"ENST00000551911",4,1332,"ENSG00000135469","COQ10A","GO:0005739(mitochondrion);GO:0005743(mitochondrial inner membrane);GO:0006744(ubiquinone biosynthetic process);GO:0016020(membrane);GO:0045333(cellular respiration);GO:0048039(ubiquinone binding)","NA","K18588","NA","coenzyme Q10A [Source:HGNC Symbol;Acc:HGNC:26515]",{"v":1.229285,"d":"1.23"},{"v":0.971581,"d":"0.97"},{"v":0.9399,"d":"0.94"},{"v":0.796475,"d":"0.80"},{"v":0.635146,"d":"0.64"},{"v":0.783135,"d":"0.78"},{"v":1.41810926350352,"d":"1.42"},{"v":0.503968694666129,"d":"0.50"},{"v":0.627553904451307,"d":"0.63"},1,"up","no"]
[48625,0,"chr12","+",119178642,119194748,"ENST00000281938",3,2152,"ENSG00000152137","HSPB8","GO:0005515(protein binding);GO:0005622(intracellular);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0006468(protein phosphorylation);GO:0034620(cellular response to unfolded protein);GO:0042802(identical protein binding);GO:0042803(protein homodimerization activity);GO:0101031(chaperone complex);GO:1900034(regulation of cellular response to heat);GO:1905337(positive regulation of aggrephagy)","NA","K08879","NA","heat shock protein family B (small) member 8 [Source:HGNC Symbol;Acc:HGNC:30171]",{"v":0.852537,"d":"0.85"},{"v":0.660494,"d":"0.66"},{"v":0.895506,"d":"0.90"},{"v":1.198744,"d":"1.20"},{"v":0.830767,"d":"0.83"},{"v":1.255356,"d":"1.26"},{"v":0.733222075657858,"d":"0.73"},{"v":-0.447677872071936,"d":"-0.45"},{"v":0.633211186060523,"d":"0.63"},1,"down","no"]
[176000,0,"chr7","-",549198,727281,"ENST00000537384",11,2472,"ENSG00000188191","PRKAR1B","GO:0000166(nucleotide binding);GO:0001932(regulation of protein phosphorylation);GO:0003091(renal water homeostasis);GO:0004862(cAMP-dependent protein kinase inhibitor activity);GO:0005515(protein binding);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0005952(cAMP-dependent protein kinase complex);GO:0006468(protein phosphorylation);GO:0007596(blood coagulation);GO:0007611(learning or memory);GO:0008603(cAMP-dependent protein kinase regulator activity);GO:0016020(membrane);GO:0019934(cGMP-mediated signaling);GO:0030552(cAMP binding);GO:0034199(activation of protein kinase A activity);GO:0034236(protein kinase A catalytic subunit binding);GO:0045202(synapse);GO:0045859(regulation of protein kinase activity);GO:0047555(3',5'-cyclic-GMP phosphodiesterase activity);GO:0050804(modulation of chemical synaptic transmission);GO:0071377(cellular response to glucagon stimulus);GO:0097546(ciliary base);GO:0098685(Schaffer collateral - CA1 synapse);GO:0098686(hippocampal mossy fiber to CA3 synapse);GO:0098693(regulation of synaptic vesicle cycle);GO:0098978(glutamatergic synapse);GO:2000480(negative regulation of cAMP-dependent protein kinase activity)","04910(Insulin signaling pathway)","NA","NA","protein kinase cAMP-dependent type I regulatory subunit beta [Source:HGNC Symbol;Acc:HGNC:9390]",{"v":0.466198,"d":"0.47"},{"v":1.700017,"d":"1.70"},{"v":1.701982,"d":"1.70"},{"v":1.629042,"d":"1.63"},0,{"v":0.694662,"d":"0.69"},{"v":1.66466856363805,"d":"1.66"},{"v":0.735234964567588,"d":"0.74"},{"v":0.635815894602045,"d":"0.64"},1,"up","no"]
[52872,0,"chr13","+",97434169,97469128,"ENST00000245304",2,5540,"ENSG00000125249","RAP2A","GO:0000166(nucleotide binding);GO:0000287(magnesium ion binding);GO:0001934(positive regulation of protein phosphorylation);GO:0003924(GTPase activity);GO:0005515(protein binding);GO:0005525(GTP binding);GO:0005768(endosome);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0007165(signal transduction);GO:0016020(membrane);GO:0019003(GDP binding);GO:0030033(microvillus assembly);GO:0030336(negative regulation of cell migration);GO:0030496(midbody);GO:0031532(actin cytoskeleton reorganization);GO:0031954(positive regulation of protein autophosphorylation);GO:0032486(Rap protein signal transduction);GO:0034613(cellular protein localization);GO:0035690(cellular response to drug);GO:0045184(establishment of protein localization);GO:0046328(regulation of JNK cascade);GO:0048814(regulation of dendrite morphogenesis);GO:0055037(recycling endosome);GO:0055038(recycling endosome membrane);GO:0072659(protein localization to plasma membrane)","NA","K07837","NA","RAP2A, member of RAS oncogene family [Source:HGNC Symbol;Acc:HGNC:9861]",{"v":9.62568,"d":"9.63"},{"v":10.036109,"d":"10.04"},{"v":10.031605,"d":"10.03"},{"v":7.660948,"d":"7.66"},{"v":8.196062,"d":"8.20"},{"v":7.763179,"d":"7.76"},{"v":1.25711923812295,"d":"1.26"},{"v":0.330121496289946,"d":"0.33"},{"v":0.638684021241126,"d":"0.64"},1,"up","no"]
[111617,0,"chr2","+",38875962,38882707,"ENST00000340556",5,739,"ENSG00000188010","MORN2","GO:0001669(acrosomal vesicle);GO:0005515(protein binding);GO:0005634(nucleus);GO:0007283(spermatogenesis);GO:0030154(cell differentiation);GO:0031410(cytoplasmic vesicle)","NA","NA","NA","MORN repeat containing 2 [Source:HGNC Symbol;Acc:HGNC:30166]",{"v":13.839375,"d":"13.84"},{"v":0.190489,"d":"0.19"},{"v":3.019381,"d":"3.02"},{"v":12.995433,"d":"13.00"},{"v":0.181596,"d":"0.18"},{"v":13.532975,"d":"13.53"},{"v":0.638309339077598,"d":"0.64"},{"v":-0.647672338927642,"d":"-0.65"},{"v":0.641803609522807,"d":"0.64"},1,"down","no"]
[134419,0,"chr22","+",37675652,37677228,"ENST00000464120",2,303,"ENSG00000100097","LGALS1","GO:0002317(plasma cell differentiation);GO:0003723(RNA binding);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0005615(extracellular space);GO:0005622(intracellular);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005788(endoplasmic reticulum lumen);GO:0005829(cytosol);GO:0006915(apoptotic process);GO:0009986(cell surface);GO:0010812(negative regulation of cell-substrate adhesion);GO:0010977(negative regulation of neuron projection development);GO:0030246(carbohydrate binding);GO:0030395(lactose binding);GO:0031295(T cell costimulation);GO:0034120(positive regulation of erythrocyte aggregation);GO:0035900(response to isolation stress);GO:0042493(response to drug);GO:0042803(protein homodimerization activity);GO:0042981(regulation of apoptotic process);GO:0043123(positive regulation of I-kappaB kinase/NF-kappaB signaling);GO:0043236(laminin binding);GO:0043687(post-translational protein modification);GO:0044267(cellular protein metabolic process);GO:0045445(myoblast differentiation);GO:0046598(positive regulation of viral entry into host cell);GO:0048678(response to axon injury);GO:0062023(collagen-containing extracellular matrix);GO:0070062(extracellular exosome);GO:0071333(cellular response to glucose stimulus);GO:0071407(cellular response to organic cyclic compound)","NA","K06830","NA","galectin 1 [Source:HGNC Symbol;Acc:HGNC:6561]",{"v":11.364474,"d":"11.36"},{"v":10.566055,"d":"10.57"},{"v":9.518543,"d":"9.52"},{"v":14.531953,"d":"14.53"},{"v":12.10351,"d":"12.10"},{"v":15.460052,"d":"15.46"},{"v":0.747088424978291,"d":"0.75"},{"v":-0.42064908516897,"d":"-0.42"},{"v":0.644248991298367,"d":"0.64"},1,"down","no"]
[57491,0,"chr14","+",64388350,64460004,"ENST00000216605",28,3136,"ENSG00000100714","MTHFD1","GO:0000105(histidine biosynthetic process);GO:0000166(nucleotide binding);GO:0001780(neutrophil homeostasis);GO:0001843(neural tube closure);GO:0003824(catalytic activity);GO:0004329(formate-tetrahydrofolate ligase activity);GO:0004477(methenyltetrahydrofolate cyclohydrolase activity);GO:0004486(methylenetetrahydrofolate dehydrogenase [NAD(P)+] activity);GO:0004487(methylenetetrahydrofolate dehydrogenase (NAD+) activity);GO:0004488(methylenetetrahydrofolate dehydrogenase (NADP+) activity);GO:0005515(protein binding);GO:0005524(ATP binding);GO:0005737(cytoplasm);GO:0005739(mitochondrion);GO:0005829(cytosol);GO:0006164(purine nucleotide biosynthetic process);GO:0006555(methionine metabolic process);GO:0006730(one-carbon metabolic process);GO:0007507(heart development);GO:0008152(metabolic process);GO:0008652(cellular amino acid biosynthetic process);GO:0009069(serine family amino acid metabolic process);GO:0009070(serine family amino acid biosynthetic process);GO:0009086(methionine biosynthetic process);GO:0009113(purine nucleobase biosynthetic process);GO:0009257(10-formyltetrahydrofolate biosynthetic process);GO:0016020(membrane);GO:0016491(oxidoreductase activity);GO:0016787(hydrolase activity);GO:0016874(ligase activity);GO:0019346(transsulfuration);GO:0035999(tetrahydrofolate interconversion);GO:0046655(folic acid metabolic process);GO:0048702(embryonic neurocranium morphogenesis);GO:0048703(embryonic viscerocranium morphogenesis);GO:0055114(oxidation-reduction process);GO:0061053(somite development);GO:0070062(extracellular exosome)","00670(One carbon pool by folate)","K00288","3.5.4.9;6.3.4.3;EC:1.5.1.5","methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1 [Source:HGNC Symbol;Acc:HGNC:7432]",{"v":2.278381,"d":"2.28"},{"v":0.007127,"d":"0.01"},{"v":0.19614,"d":"0.20"},{"v":3.82682,"d":"3.83"},{"v":0.189699,"d":"0.19"},{"v":0.056326,"d":"0.06"},{"v":0.609315601256616,"d":"0.61"},{"v":-0.714738414490459,"d":"-0.71"},{"v":0.650328185110416,"d":"0.65"},1,"down","no"]
[36501,0,"chr11","+",114400666,114408909,"ENST00000542140",5,1908,"ENSG00000076053","RBM7","GO:0000381(regulation of alternative mRNA splicing, via spliceosome);GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0003727(single-stranded RNA binding);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0051321(meiotic cell cycle)","NA","K13188","NA","RNA binding motif protein 7 [Source:HGNC Symbol;Acc:HGNC:9904]",0,{"v":2.222123,"d":"2.22"},{"v":0.608986,"d":"0.61"},0,0,{"v":1.395948,"d":"1.40"},{"v":2.02809058790155,"d":"2.03"},{"v":1.02012209405602,"d":"1.02"},{"v":0.652995967301767,"d":"0.65"},1,"up","no"]
[23082,0,"chr10","-",93306429,93482334,"ENST00000359263",54,6860,"ENSG00000138119","MYOF","GO:0001778(plasma membrane repair);GO:0005515(protein binding);GO:0005543(phospholipid binding);GO:0005634(nucleus);GO:0005635(nuclear envelope);GO:0005886(plasma membrane);GO:0005901(caveola);GO:0006071(glycerol metabolic process);GO:0006936(muscle contraction);GO:0007520(myoblast fusion);GO:0008015(blood circulation);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0030659(cytoplasmic vesicle membrane);GO:0030947(regulation of vascular endothelial growth factor receptor signaling pathway);GO:0031410(cytoplasmic vesicle);GO:0031965(nuclear membrane);GO:0033292(T-tubule organization);GO:0034605(cellular response to heat);GO:0043231(intracellular membrane-bounded organelle);GO:0048747(muscle fiber development);GO:0070062(extracellular exosome)","NA","K22125","NA","myoferlin [Source:HGNC Symbol;Acc:HGNC:3656]",{"v":73.573624,"d":"73.57"},{"v":73.145287,"d":"73.15"},{"v":73.999275,"d":"74.00"},{"v":25.085402,"d":"25.09"},{"v":79.455246,"d":"79.46"},{"v":73.086151,"d":"73.09"},{"v":1.24259507710883,"d":"1.24"},{"v":0.31335624375988,"d":"0.31"},{"v":0.655296333463937,"d":"0.66"},1,"up","no"]
[136189,0,"chr3","+",3126940,3149023,"ENST00000251607",8,2252,"ENSG00000072756","TRNT1","GO:0000049(tRNA binding);GO:0000166(nucleotide binding);GO:0001680(tRNA 3'-terminal CCA addition);GO:0003723(RNA binding);GO:0005524(ATP binding);GO:0005622(intracellular);GO:0005654(nucleoplasm);GO:0005739(mitochondrion);GO:0005759(mitochondrial matrix);GO:0006396(RNA processing);GO:0008033(tRNA processing);GO:0016740(transferase activity);GO:0016779(nucleotidyltransferase activity);GO:0034062(5'-3' RNA polymerase activity);GO:0042780(tRNA 3'-end processing);GO:0052927(CTP:tRNA cytidylyltransferase activity);GO:0052928(CTP:3'-cytidine-tRNA cytidylyltransferase activity);GO:0052929(ATP:3'-cytidine-cytidine-tRNA adenylyltransferase activity);GO:1990180(mitochondrial tRNA 3'-end processing)","03013(RNA transport)","K00974","3.1.3.-;3.1.4.-;EC:2.7.7.72","tRNA nucleotidyl transferase 1 [Source:HGNC Symbol;Acc:HGNC:17341]",{"v":0.738208,"d":"0.74"},{"v":3.095609,"d":"3.10"},{"v":3.925284,"d":"3.93"},{"v":0.81191,"d":"0.81"},{"v":0.901208,"d":"0.90"},{"v":3.768481,"d":"3.77"},{"v":1.41548132214706,"d":"1.42"},{"v":0.501292712420208,"d":"0.50"},{"v":0.657623164515521,"d":"0.66"},1,"up","no"]
[135044,0,"chr22","+",41301525,41360147,"ENST00000352645",23,5906,"ENSG00000100403","ZC3H7B","GO:0003723(RNA binding);GO:0005515(protein binding);GO:0005634(nucleus);GO:0010608(posttranscriptional regulation of gene expression);GO:0016032(viral process);GO:0035196(production of miRNAs involved in gene silencing by miRNA);GO:0035198(miRNA binding);GO:0046872(metal ion binding)","NA","NA","NA","zinc finger CCCH-type containing 7B [Source:HGNC Symbol;Acc:HGNC:30869]",{"v":23.450079,"d":"23.45"},{"v":23.836599,"d":"23.84"},{"v":24.055376,"d":"24.06"},{"v":28.433626,"d":"28.43"},{"v":27.540298,"d":"27.54"},{"v":28.620863,"d":"28.62"},{"v":0.843338656316967,"d":"0.84"},{"v":-0.245816009772494,"d":"-0.25"},{"v":0.660055417490779,"d":"0.66"},1,"down","no"]
[34076,0,"chr11","+",73787872,73865133,"ENST00000508278",9,1560,"ENSG00000175581","MRPL48","GO:0005515(protein binding);GO:0005739(mitochondrion);GO:0005743(mitochondrial inner membrane);GO:0005761(mitochondrial ribosome);GO:0005762(mitochondrial large ribosomal subunit);GO:0005840(ribosome);GO:0070125(mitochondrial translational elongation);GO:0070126(mitochondrial translational termination)","NA","K17429","NA","mitochondrial ribosomal protein L48 [Source:HGNC Symbol;Acc:HGNC:16653]",{"v":3.636543,"d":"3.64"},{"v":4.61222,"d":"4.61"},{"v":4.044861,"d":"4.04"},{"v":3.768688,"d":"3.77"},{"v":2.543151,"d":"2.54"},{"v":2.806415,"d":"2.81"},{"v":1.34824320533295,"d":"1.35"},{"v":0.43108076319603,"d":"0.43"},{"v":0.665763407957635,"d":"0.67"},1,"up","no"]
[115993,0,"chr2","-",106697331,106698676,"ENST00000443590",1,1346,"ENSG00000214199","EEF1A1P12","NA","NA","NA","NA","eukaryotic translation elongation factor 1 alpha 1 pseudogene 12 [Source:HGNC Symbol;Acc:HGNC:3195]",{"v":1.342781,"d":"1.34"},{"v":1.228979,"d":"1.23"},{"v":1.05052,"d":"1.05"},{"v":0.852774,"d":"0.85"},{"v":1.010001,"d":"1.01"},{"v":0.805829,"d":"0.81"},{"v":1.35736887151484,"d":"1.36"},{"v":0.440812833349902,"d":"0.44"},{"v":0.668114959062508,"d":"0.67"},1,"up","no"]
[76228,0,"chr16","-",67175604,67179552,"ENST00000561679",3,2824,"ENSG00000196123","KIAA0895L","NA","NA","NA","NA","KIAA0895 like [Source:HGNC Symbol;Acc:HGNC:34408]",{"v":1.540307,"d":"1.54"},{"v":1.38337,"d":"1.38"},{"v":1.918257,"d":"1.92"},{"v":1.420121,"d":"1.42"},{"v":2.914454,"d":"2.91"},{"v":1.961072,"d":"1.96"},{"v":0.769092358577284,"d":"0.77"},{"v":-0.378771236283423,"d":"-0.38"},{"v":0.670595618450245,"d":"0.67"},1,"down","no"]
[24727,0,"chr10","-",119140913,119165667,"ENST00000355697",14,1363,"ENSG00000183605","SFXN4","GO:0005739(mitochondrion);GO:0005743(mitochondrial inner membrane);GO:0006811(ion transport);GO:0006865(amino acid transport);GO:0015075(ion transmembrane transporter activity);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0034220(ion transmembrane transport);GO:0043231(intracellular membrane-bounded organelle);GO:0055085(transmembrane transport)","NA","NA","NA","sideroflexin 4 [Source:HGNC Symbol;Acc:HGNC:16088]",{"v":6.781053,"d":"6.78"},{"v":6.653727,"d":"6.65"},{"v":6.560357,"d":"6.56"},{"v":6.037931,"d":"6.04"},{"v":3.397605,"d":"3.40"},{"v":5.685059,"d":"5.69"},{"v":1.32237765775752,"d":"1.32"},{"v":0.403134254882966,"d":"0.40"},{"v":0.673041054574852,"d":"0.67"},1,"up","no"]
[58519,0,"chr14","+",74881916,74902452,"ENST00000238671",14,1464,"ENSG00000119689","DLST","GO:0004149(dihydrolipoyllysine-residue succinyltransferase activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005739(mitochondrion);GO:0005759(mitochondrial matrix);GO:0006091(generation of precursor metabolites and energy);GO:0006099(tricarboxylic acid cycle);GO:0006103(2-oxoglutarate metabolic process);GO:0006104(succinyl-CoA metabolic process);GO:0006554(lysine catabolic process);GO:0016020(membrane);GO:0016740(transferase activity);GO:0016746(transferase activity, transferring acyl groups);GO:0033512(L-lysine catabolic process to acetyl-CoA via saccharopine);GO:0045252(oxoglutarate dehydrogenase complex);GO:0106077(histone succinylation)","00020(Citrate cycle (TCA cycle));00310(Lysine degradation);00380(Tryptophan metabolism)","K00658","EC:2.3.1.61","dihydrolipoamide S-succinyltransferase [Source:HGNC Symbol;Acc:HGNC:2911]",0,0,{"v":1.848838,"d":"1.85"},{"v":0.438307,"d":"0.44"},{"v":0.397817,"d":"0.40"},{"v":2.255713,"d":"2.26"},{"v":0.597973955289364,"d":"0.60"},{"v":-0.741845445569573,"d":"-0.74"},{"v":0.6755230404945,"d":"0.68"},1,"down","no"]
[189852,0,"chr8","-",66922271,66925541,"ENST00000521127",2,560,"ENSG00000245910","SNHG6","NA","NA","NA","NA","small nucleolar RNA host gene 6 [Source:HGNC Symbol;Acc:HGNC:32965]",{"v":3.443283,"d":"3.44"},{"v":3.522757,"d":"3.52"},{"v":4.019178,"d":"4.02"},{"v":3.265905,"d":"3.27"},{"v":2.097664,"d":"2.10"},{"v":2.749539,"d":"2.75"},{"v":1.35400859941714,"d":"1.35"},{"v":0.437236901613845,"d":"0.44"},{"v":0.680440311482671,"d":"0.68"},1,"up","no"]
[72970,0,"chr16","+",27313926,27364778,"ENST00000543915",10,3539,"ENSG00000077238","IL4R","GO:0002376(immune system process);GO:0002532(production of molecular mediator involved in inflammatory response);GO:0002639(positive regulation of immunoglobulin production);GO:0004896(cytokine receptor activity);GO:0004913(interleukin-4 receptor activity);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0005615(extracellular space);GO:0005886(plasma membrane);GO:0005887(integral component of plasma membrane);GO:0006955(immune response);GO:0007165(signal transduction);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016064(immunoglobulin mediated immune response);GO:0019221(cytokine-mediated signaling pathway);GO:0030728(ovulation);GO:0035771(interleukin-4-mediated signaling pathway);GO:0042127(regulation of cell population proliferation);GO:0042832(defense response to protozoan);GO:0043032(positive regulation of macrophage activation);GO:0043235(receptor complex);GO:0043306(positive regulation of mast cell degranulation);GO:0043627(response to estrogen);GO:0045626(negative regulation of T-helper 1 cell differentiation);GO:0045630(positive regulation of T-helper 2 cell differentiation);GO:0090197(positive regulation of chemokine secretion);GO:0120162(positive regulation of cold-induced thermogenesis);GO:1901741(positive regulation of myoblast fusion);GO:1990834(response to odorant)","04060(Cytokine-cytokine receptor interaction);04151(PI3K-Akt signaling pathway);04630(Jak-STAT signaling pathway);04640(Hematopoietic cell lineage);04658(Th1 and Th2 cell differentiation);04659(Th17 cell differentiation);05200(Pathways in cancer);05321(Inflammatory bowel disease (IBD))","K05071","NA","interleukin 4 receptor [Source:HGNC Symbol;Acc:HGNC:6015]",{"v":1.530818,"d":"1.53"},{"v":0.375402,"d":"0.38"},{"v":0.506707,"d":"0.51"},{"v":0.58751,"d":"0.59"},{"v":0.968533,"d":"0.97"},{"v":0.187851,"d":"0.19"},{"v":1.38364315721024,"d":"1.38"},{"v":0.468471918622675,"d":"0.47"},{"v":0.682759543314497,"d":"0.68"},1,"up","no"]
[163217,0,"chr5","-",138946724,139198368,"ENST00000394817",10,1889,"ENSG00000120725","SIL1","GO:0000774(adenyl-nucleotide exchange factor activity);GO:0005515(protein binding);GO:0005615(extracellular space);GO:0005737(cytoplasm);GO:0005783(endoplasmic reticulum);GO:0005788(endoplasmic reticulum lumen);GO:0006457(protein folding);GO:0006886(intracellular protein transport);GO:0015031(protein transport);GO:0050790(regulation of catalytic activity);GO:0051082(unfolded protein binding)","04141(Protein processing in endoplasmic reticulum)","K14001","NA","SIL1 nucleotide exchange factor [Source:HGNC Symbol;Acc:HGNC:24624]",{"v":26.264345,"d":"26.26"},{"v":25.9319,"d":"25.93"},{"v":26.608421,"d":"26.61"},{"v":18.704031,"d":"18.70"},{"v":22.368902,"d":"22.37"},{"v":23.341364,"d":"23.34"},{"v":1.22340333854765,"d":"1.22"},{"v":0.290900118166862,"d":"0.29"},{"v":0.685027976043555,"d":"0.69"},1,"up","no"]
[92997,0,"chr18","-",10670248,11148762,"ENST00000383408",53,9718,"ENSG00000154864","PIEZO2","GO:0005261(cation channel activity);GO:0005886(plasma membrane);GO:0006811(ion transport);GO:0006812(cation transport);GO:0008381(mechanosensitive ion channel activity);GO:0009612(response to mechanical stimulus);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0034220(ion transmembrane transport);GO:0042391(regulation of membrane potential);GO:0050896(response to stimulus);GO:0050974(detection of mechanical stimulus involved in sensory perception);GO:0050982(detection of mechanical stimulus);GO:0055085(transmembrane transport);GO:0071260(cellular response to mechanical stimulus);GO:0098655(cation transmembrane transport)","NA","K22128","NA","piezo type mechanosensitive ion channel component 2 [Source:HGNC Symbol;Acc:HGNC:26270]",{"v":0.712155,"d":"0.71"},{"v":0.790144,"d":"0.79"},{"v":0.647784,"d":"0.65"},{"v":0.712853,"d":"0.71"},{"v":1.108414,"d":"1.11"},{"v":0.891311,"d":"0.89"},{"v":0.79263453438021,"d":"0.79"},{"v":-0.335272269275018,"d":"-0.34"},{"v":0.68726260540998,"d":"0.69"},1,"down","no"]
[93671,0,"chr18","+",24426634,24453510,"ENST00000648078",12,3203,"ENSG00000154059","IMPACT","GO:0000122(negative regulation of transcription by RNA polymerase II);GO:0001933(negative regulation of protein phosphorylation);GO:0003674(molecular_function);GO:0003779(actin binding);GO:0005515(protein binding);GO:0005575(cellular_component);GO:0005737(cytoplasm);GO:0005844(polysome);GO:0006417(regulation of translation);GO:0006446(regulation of translational initiation);GO:0007399(nervous system development);GO:0008150(biological_process);GO:0030154(cell differentiation);GO:0031333(negative regulation of protein complex assembly);GO:0031953(negative regulation of protein autophosphorylation);GO:0034198(cellular response to amino acid starvation);GO:0042149(cellular response to glucose starvation);GO:0043022(ribosome binding);GO:0045666(positive regulation of neuron differentiation);GO:0060548(negative regulation of cell death);GO:0060733(regulation of eIF2 alpha phosphorylation by amino acid starvation);GO:0070301(cellular response to hydrogen peroxide);GO:0071264(positive regulation of translational initiation in response to starvation);GO:0071468(cellular response to acidic pH);GO:0071494(cellular response to UV-C);GO:0072755(cellular response to benomyl);GO:0097201(negative regulation of transcription from RNA polymerase II promoter in response to stress);GO:1990138(neuron projection extension);GO:1990253(cellular response to leucine starvation)","NA","NA","NA","impact RWD domain protein [Source:HGNC Symbol;Acc:HGNC:20387]",{"v":0.518643,"d":"0.52"},{"v":0.131111,"d":"0.13"},{"v":0.327788,"d":"0.33"},{"v":0.266851,"d":"0.27"},{"v":0.049233,"d":"0.05"},{"v":0.363083,"d":"0.36"},{"v":1.43932493775463,"d":"1.44"},{"v":0.5253923274273,"d":"0.53"},{"v":0.689722580161218,"d":"0.69"},1,"up","no"]
[183349,0,"chr7","+",120950795,120956978,"ENST00000445699",4,1723,"ENSG00000071243","ING3","GO:0000812(Swr1 complex);GO:0004402(histone acetyltransferase activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0006325(chromatin organization);GO:0032777(Piccolo NuA4 histone acetyltransferase complex);GO:0035064(methylated histone binding);GO:0035267(NuA4 histone acetyltransferase complex);GO:0040008(regulation of growth);GO:0043065(positive regulation of apoptotic process);GO:0043967(histone H4 acetylation);GO:0043968(histone H2A acetylation);GO:0046872(metal ion binding)","NA","K11319","NA","inhibitor of growth family member 3 [Source:HGNC Symbol;Acc:HGNC:14587]",{"v":0.525289,"d":"0.53"},{"v":0.271592,"d":"0.27"},{"v":0.870621,"d":"0.87"},{"v":0.870409,"d":"0.87"},{"v":0.100423,"d":"0.10"},{"v":0.173782,"d":"0.17"},{"v":1.45682474615897,"d":"1.46"},{"v":0.542827333782142,"d":"0.54"},{"v":0.694408827611291,"d":"0.69"},1,"up","no"]
[49383,0,"chr12","+",123248278,123256945,"ENST00000543139",3,3733,"ENSG00000130921","C12orf65","GO:0003747(translation release factor activity);GO:0005739(mitochondrion);GO:0005762(mitochondrial large ribosomal subunit);GO:0006412(translation);GO:0006415(translational termination)","NA","NA","NA","chromosome 12 open reading frame 65 [Source:HGNC Symbol;Acc:HGNC:26784]",{"v":0.471079,"d":"0.47"},{"v":0.453759,"d":"0.45"},{"v":0.732256,"d":"0.73"},{"v":0.49608,"d":"0.50"},{"v":0.473262,"d":"0.47"},{"v":0.267209,"d":"0.27"},{"v":1.34009353435483,"d":"1.34"},{"v":0.422333699817755,"d":"0.42"},{"v":0.696444423476003,"d":"0.70"},1,"up","no"]
[108716,0,"chr19","+",57240632,57262728,"ENST00000414468",4,10169,"ENSG00000204524","ZNF805","GO:0000981(DNA-binding transcription factor activity, RNA polymerase II-specific);GO:0003676(nucleic acid binding);GO:0003677(DNA binding);GO:0005622(intracellular);GO:0005634(nucleus);GO:0006355(regulation of transcription, DNA-templated);GO:0006357(regulation of transcription by RNA polymerase II);GO:0046872(metal ion binding)","NA","NA","NA","zinc finger protein 805 [Source:HGNC Symbol;Acc:HGNC:23272]",{"v":0.468261,"d":"0.47"},{"v":0.4738,"d":"0.47"},{"v":0.366238,"d":"0.37"},{"v":0.392221,"d":"0.39"},{"v":0.332123,"d":"0.33"},{"v":0.269546,"d":"0.27"},{"v":1.31634184869553,"d":"1.32"},{"v":0.39653419984318,"d":"0.40"},{"v":0.698900961928622,"d":"0.70"},1,"up","no"]
[156341,0,"chr4","+",173315841,173323127,"ENST00000515862",3,3569,"ENSG00000109586","GALNT7","GO:0000139(Golgi membrane);GO:0004653(polypeptide N-acetylgalactosaminyltransferase activity);GO:0005794(Golgi apparatus);GO:0005975(carbohydrate metabolic process);GO:0006486(protein glycosylation);GO:0006493(protein O-linked glycosylation);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016266(O-glycan processing);GO:0016740(transferase activity);GO:0016757(transferase activity, transferring glycosyl groups);GO:0030246(carbohydrate binding);GO:0046872(metal ion binding);GO:0070062(extracellular exosome)","00512(Mucin type O-glycan biosynthesis)","K00710","EC:2.4.1.41","polypeptide N-acetylgalactosaminyltransferase 7 [Source:HGNC Symbol;Acc:HGNC:4129]",{"v":0.246024,"d":"0.25"},{"v":0.201494,"d":"0.20"},{"v":0.137755,"d":"0.14"},{"v":0.12876,"d":"0.13"},{"v":0.488937,"d":"0.49"},{"v":0.177802,"d":"0.18"},{"v":0.735730654595417,"d":"0.74"},{"v":-0.442750391647863,"d":"-0.44"},{"v":0.701543389548848,"d":"0.70"},1,"down","no"]
[44223,0,"chr12","+",56158369,56161298,"ENST00000551589",5,1438,"ENSG00000092841","MYL6","GO:0003774(motor activity);GO:0005509(calcium ion binding);GO:0005515(protein binding);GO:0005829(cytosol);GO:0005903(brush border);GO:0006936(muscle contraction);GO:0007519(skeletal muscle tissue development);GO:0008307(structural constituent of muscle);GO:0016020(membrane);GO:0016459(myosin complex);GO:0016461(unconventional myosin complex);GO:0030049(muscle filament sliding);GO:0030898(actin-dependent ATPase activity);GO:0031982(vesicle);GO:0070062(extracellular exosome)","04270(Vascular smooth muscle contraction);04530(Tight junction);04921(Oxytocin signaling pathway)","K12751","NA","myosin light chain 6 [Source:HGNC Symbol;Acc:HGNC:7587]",{"v":110.172676,"d":"110.17"},{"v":47.137051,"d":"47.14"},{"v":55.519188,"d":"55.52"},{"v":109.386719,"d":"109.39"},{"v":29.599163,"d":"29.60"},{"v":32.42918,"d":"32.43"},{"v":1.24159984844272,"d":"1.24"},{"v":0.312200286533502,"d":"0.31"},{"v":0.703754469640548,"d":"0.70"},1,"up","no"]
[172055,0,"chr6","-",78940546,78982943,"ENST00000479165",17,5694,"ENSG00000146247","PHIP","GO:0001932(regulation of protein phosphorylation);GO:0005158(insulin receptor binding);GO:0005515(protein binding);GO:0005634(nucleus);GO:0006357(regulation of transcription by RNA polymerase II);GO:0007010(cytoskeleton organization);GO:0008284(positive regulation of cell population proliferation);GO:0008286(insulin receptor signaling pathway);GO:0008360(regulation of cell shape);GO:0022604(regulation of cell morphogenesis);GO:0043066(negative regulation of apoptotic process);GO:0043568(positive regulation of insulin-like growth factor receptor signaling pathway);GO:0045840(positive regulation of mitotic nuclear division);GO:0045893(positive regulation of transcription, DNA-templated);GO:0045944(positive regulation of transcription by RNA polymerase II);GO:0070577(lysine-acetylated histone binding);GO:2001237(negative regulation of extrinsic apoptotic signaling pathway)","NA","K11797","NA","pleckstrin homology domain interacting protein [Source:HGNC Symbol;Acc:HGNC:15673]",{"v":0.231057,"d":"0.23"},{"v":0.47619,"d":"0.48"},{"v":0.54153,"d":"0.54"},{"v":0.258151,"d":"0.26"},{"v":0.459696,"d":"0.46"},{"v":0.219669,"d":"0.22"},{"v":1.33200606709645,"d":"1.33"},{"v":0.413600653692984,"d":"0.41"},{"v":0.706091947936561,"d":"0.71"},1,"up","no"]
[172382,0,"chr6","+",87472974,87512336,"ENST00000369552",8,1854,"ENSG00000164414","SLC35A1","GO:0000139(Golgi membrane);GO:0005456(CMP-N-acetylneuraminate transmembrane transporter activity);GO:0005794(Golgi apparatus);GO:0005887(integral component of plasma membrane);GO:0005975(carbohydrate metabolic process);GO:0006464(cellular protein modification process);GO:0008643(carbohydrate transport);GO:0015136(sialic acid transmembrane transporter activity);GO:0015165(pyrimidine nucleotide-sugar transmembrane transporter activity);GO:0015782(CMP-N-acetylneuraminate transmembrane transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0030173(integral component of Golgi membrane);GO:0090481(pyrimidine nucleotide-sugar transmembrane transport)","NA","K15272","NA","solute carrier family 35 member A1 [Source:HGNC Symbol;Acc:HGNC:11021]",{"v":19.012989,"d":"19.01"},{"v":23.487051,"d":"23.49"},{"v":21.532269,"d":"21.53"},{"v":16.411934,"d":"16.41"},{"v":17.329411,"d":"17.33"},{"v":19.197496,"d":"19.20"},{"v":1.20955252873783,"d":"1.21"},{"v":0.274473424385213,"d":"0.27"},{"v":0.710816978268929,"d":"0.71"},1,"up","no"]
[56826,0,"chr14","+",55027236,55049489,"ENST00000555846",3,6903,"ENSG00000180008","SOCS4","GO:0005515(protein binding);GO:0007175(negative regulation of epidermal growth factor-activated receptor activity);GO:0009968(negative regulation of signal transduction);GO:0016567(protein ubiquitination);GO:0032436(positive regulation of proteasomal ubiquitin-dependent protein catabolic process);GO:0035556(intracellular signal transduction);GO:0040008(regulation of growth)","04630(Jak-STAT signaling pathway);04910(Insulin signaling pathway);04917(Prolactin signaling pathway);04930(Type II diabetes mellitus)","K04697","NA","suppressor of cytokine signaling 4 [Source:HGNC Symbol;Acc:HGNC:19392]",{"v":1.938014,"d":"1.94"},{"v":1.281565,"d":"1.28"},{"v":2.318504,"d":"2.32"},{"v":1.835636,"d":"1.84"},{"v":0.019167,"d":"0.02"},{"v":2.187923,"d":"2.19"},{"v":1.36988828824907,"d":"1.37"},{"v":0.454058248981212,"d":"0.45"},{"v":0.712885145232088,"d":"0.71"},1,"up","no"]
[93565,0,"chr18","+",23503533,23531743,"ENST00000590870",20,2102,"ENSG00000141452","RMC1","GO:0005515(protein binding);GO:0005764(lysosome);GO:0005765(lysosomal membrane);GO:0005768(endosome);GO:0006914(autophagy);GO:0010506(regulation of autophagy);GO:0016020(membrane);GO:0031902(late endosome membrane);GO:0035658(Mon1-Ccz1 complex)","NA","NA","NA","regulator of MON1-CCZ1 [Source:HGNC Symbol;Acc:HGNC:24326]",0,{"v":2.544354,"d":"2.54"},{"v":0.089338,"d":"0.09"},{"v":0.240853,"d":"0.24"},{"v":2.128391,"d":"2.13"},{"v":1.532113,"d":"1.53"},{"v":0.675070751023298,"d":"0.68"},{"v":-0.566889382647732,"d":"-0.57"},{"v":0.715035216618198,"d":"0.72"},1,"down","no"]
[19932,0,"chr10","-",27145419,27155266,"ENST00000477432",3,3474,"ENSG00000136758","YME1L1","GO:0000166(nucleotide binding);GO:0004176(ATP-dependent peptidase activity);GO:0004222(metalloendopeptidase activity);GO:0005515(protein binding);GO:0005524(ATP binding);GO:0005739(mitochondrion);GO:0005743(mitochondrial inner membrane);GO:0006508(proteolysis);GO:0006515(protein quality control for misfolded or incompletely synthesized proteins);GO:0006851(mitochondrial calcium ion transmembrane transport);GO:0007005(mitochondrion organization);GO:0008233(peptidase activity);GO:0008237(metallopeptidase activity);GO:0008283(cell population proliferation);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016604(nuclear body);GO:0016787(hydrolase activity);GO:0034214(protein hexamerization);GO:0034982(mitochondrial protein processing);GO:0035694(mitochondrial protein catabolic process);GO:0043066(negative regulation of apoptotic process);GO:0046872(metal ion binding)","NA","K08955","EC:3.4.24.-","YME1 like 1 ATPase [Source:HGNC Symbol;Acc:HGNC:12843]",{"v":0.507687,"d":"0.51"},{"v":0.513035,"d":"0.51"},{"v":0.690738,"d":"0.69"},{"v":0.741888,"d":"0.74"},{"v":0.743564,"d":"0.74"},{"v":0.667033,"d":"0.67"},{"v":0.795108909005173,"d":"0.80"},{"v":-0.330775609684889,"d":"-0.33"},{"v":0.717349603887586,"d":"0.72"},1,"down","no"]
[140031,0,"chr3","+",49674383,49676506,"ENST00000462439",6,829,"ENSG00000164062","APEH","GO:0003723(RNA binding);GO:0004252(serine-type endopeptidase activity);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0006415(translational termination);GO:0006508(proteolysis);GO:0008236(serine-type peptidase activity);GO:0008242(omega peptidase activity);GO:0016787(hydrolase activity);GO:0031965(nuclear membrane);GO:0042802(identical protein binding);GO:0043312(neutrophil degranulation);GO:0050435(amyloid-beta metabolic process);GO:0070062(extracellular exosome);GO:1904813(ficolin-1-rich granule lumen)","NA","NA","NA","acylaminoacyl-peptide hydrolase [Source:HGNC Symbol;Acc:HGNC:586]",{"v":1.028766,"d":"1.03"},{"v":1.862578,"d":"1.86"},{"v":0.541458,"d":"0.54"},{"v":1.219561,"d":"1.22"},{"v":1.211545,"d":"1.21"},{"v":1.958753,"d":"1.96"},{"v":0.781984569436057,"d":"0.78"},{"v":-0.354787955152326,"d":"-0.35"},{"v":0.719500118364739,"d":"0.72"},1,"down","no"]
[148212,0,"chr3","-",195068284,195271159,"ENST00000310380",4,2714,"ENSG00000173950","XXYLT1","GO:0000287(magnesium ion binding);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016266(O-glycan processing);GO:0016740(transferase activity);GO:0016757(transferase activity, transferring glycosyl groups);GO:0030145(manganese ion binding);GO:0030176(integral component of endoplasmic reticulum membrane);GO:0035252(UDP-xylosyltransferase activity);GO:0046872(metal ion binding)","NA","NA","NA","xyloside xylosyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:26639]",{"v":7.967065,"d":"7.97"},{"v":8.918895,"d":"8.92"},{"v":7.722047,"d":"7.72"},{"v":9.216294,"d":"9.22"},{"v":10.152797,"d":"10.15"},{"v":9.31862,"d":"9.32"},{"v":0.857789141838469,"d":"0.86"},{"v":-0.221305040880482,"d":"-0.22"},{"v":0.723788377025543,"d":"0.72"},1,"down","no"]
[79871,0,"chr17","+",2796438,3037741,"ENST00000254695",25,6663,"ENSG00000132359","RAP1GAP2","GO:0005096(GTPase activator activity);GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0005813(centrosome);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0008361(regulation of cell size);GO:0010977(negative regulation of neuron projection development);GO:0031965(nuclear membrane);GO:0043005(neuron projection);GO:0043547(positive regulation of GTPase activity);GO:0048471(perinuclear region of cytoplasm);GO:0051056(regulation of small GTPase mediated signal transduction)","NA","K17708","NA","RAP1 GTPase activating protein 2 [Source:HGNC Symbol;Acc:HGNC:29176]",{"v":0.018586,"d":"0.02"},{"v":0.135649,"d":"0.14"},{"v":0.009898,"d":"0.01"},{"v":0.158932,"d":"0.16"},{"v":0.011613,"d":"0.01"},{"v":0.060555,"d":"0.06"},{"v":0.710225010817828,"d":"0.71"},{"v":-0.493651928632246,"d":"-0.49"},{"v":0.726014603685494,"d":"0.73"},1,"down","no"]
[55014,0,"chr14","+",24094301,24104030,"ENST00000545054",10,2505,"ENSG00000100889","PCK2","GO:0000166(nucleotide binding);GO:0004611(phosphoenolpyruvate carboxykinase activity);GO:0004613(phosphoenolpyruvate carboxykinase (GTP) activity);GO:0005515(protein binding);GO:0005525(GTP binding);GO:0005739(mitochondrion);GO:0005759(mitochondrial matrix);GO:0005829(cytosol);GO:0006090(pyruvate metabolic process);GO:0006094(gluconeogenesis);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0016829(lyase activity);GO:0016831(carboxy-lyase activity);GO:0017076(purine nucleotide binding);GO:0019543(propionate catabolic process);GO:0030145(manganese ion binding);GO:0032869(cellular response to insulin stimulus);GO:0033993(response to lipid);GO:0042594(response to starvation);GO:0046327(glycerol biosynthetic process from pyruvate);GO:0046872(metal ion binding);GO:0070365(hepatocyte differentiation);GO:0071333(cellular response to glucose stimulus);GO:0071549(cellular response to dexamethasone stimulus)","00010(Glycolysis / Gluconeogenesis);00020(Citrate cycle (TCA cycle));00620(Pyruvate metabolism);03320(PPAR signaling pathway);04068(FoxO signaling pathway);04151(PI3K-Akt signaling pathway);04152(AMPK signaling pathway);04910(Insulin signaling pathway);04920(Adipocytokine signaling pathway);04922(Glucagon signaling pathway);04931(Insulin resistance);04964(Proximal tubule bicarbonate reclamation)","NA","NA","phosphoenolpyruvate carboxykinase 2, mitochondrial [Source:HGNC Symbol;Acc:HGNC:8725]",0,{"v":2.413512,"d":"2.41"},{"v":0.957067,"d":"0.96"},{"v":1.866637,"d":"1.87"},0,0,{"v":1.80569601909745,"d":"1.81"},{"v":0.852555041959033,"d":"0.85"},{"v":0.728320754824836,"d":"0.73"},1,"up","no"]
[154297,0,"chr4","-",113456609,113761563,"ENST00000394522",18,2696,"ENSG00000145349","CAMK2D","GO:0000166(nucleotide binding);GO:0001558(regulation of cell growth);GO:0002026(regulation of the force of heart contraction);GO:0003254(regulation of membrane depolarization);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0004683(calmodulin-dependent protein kinase activity);GO:0005515(protein binding);GO:0005516(calmodulin binding);GO:0005524(ATP binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0006357(regulation of transcription by RNA polymerase II);GO:0006468(protein phosphorylation);GO:0008016(regulation of heart contraction);GO:0010613(positive regulation of cardiac muscle hypertrophy);GO:0010649(regulation of cell communication by electrical coupling);GO:0010666(positive regulation of cardiac muscle cell apoptotic process);GO:0010880(regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum);GO:0010881(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion);GO:0016020(membrane);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0016529(sarcoplasmic reticulum);GO:0016740(transferase activity);GO:0018105(peptidyl-serine phosphorylation);GO:0018107(peptidyl-threonine phosphorylation);GO:0019871(sodium channel inhibitor activity);GO:0030666(endocytic vesicle membrane);GO:0031432(titin binding);GO:0032469(endoplasmic reticulum calcium ion homeostasis);GO:0033017(sarcoplasmic reticulum membrane);GO:0042383(sarcolemma);GO:0042802(identical protein binding);GO:0042803(protein homodimerization activity);GO:0043005(neuron projection);GO:0044325(ion channel binding);GO:0046777(protein autophosphorylation);GO:0051259(protein complex oligomerization);GO:0055119(relaxation of cardiac muscle);GO:0060314(regulation of ryanodine-sensitive calcium-release channel activity);GO:0060333(interferon-gamma-mediated signaling pathway);GO:0060341(regulation of cellular localization);GO:0071277(cellular response to calcium ion);GO:0086003(cardiac muscle cell contraction);GO:0086091(regulation of heart rate by cardiac conduction);GO:0098901(regulation of cardiac muscle cell action potential);GO:0098909(regulation of cardiac muscle cell action potential involved in regulation of contraction);GO:1900034(regulation of cellular response to heat);GO:1901725(regulation of histone deacetylase activity);GO:1901844(regulation of cell communication by electrical coupling involved in cardiac conduction);GO:1901897(regulation of relaxation of cardiac muscle);GO:1902306(negative regulation of sodium ion transmembrane transport);GO:1902514(regulation of calcium ion transmembrane transport via high voltage-gated calcium channel);GO:2000650(negative regulation of sodium ion transmembrane transporter activity)","04012(ErbB signaling pathway);04020(Calcium signaling pathway);04024(cAMP signaling pathway);04066(HIF-1 signaling pathway);04114(Oocyte meiosis);04217(Necroptosis);04261(Adrenergic signaling in cardiomyocytes);04310(Wnt signaling pathway);04360(Axon guidance);04713(Circadian entrainment);04720(Long-term potentiation);04722(Neurotrophin signaling pathway);04725(Cholinergic synapse);04728(Dopaminergic synapse);04740(Olfactory transduction);04750(Inflammatory mediator regulation of TRP channels);04911(Insulin secretion);04912(GnRH signaling pathway);04916(Melanogenesis);04921(Oxytocin signaling pathway);04922(Glucagon signaling pathway);04925(Aldosterone synthesis and secretion);04934(Cushing syndrome);04971(Gastric acid secretion);05031(Amphetamine addiction);05152(Tuberculosis);05200(Pathways in cancer);05205(Proteoglycans in cancer);05214(Glioma)","NA","NA","calcium/calmodulin dependent protein kinase II delta [Source:HGNC Symbol;Acc:HGNC:1462]",{"v":0.410616,"d":"0.41"},{"v":1.341238,"d":"1.34"},{"v":0.621533,"d":"0.62"},{"v":0.558003,"d":"0.56"},{"v":0.696543,"d":"0.70"},{"v":0.572547,"d":"0.57"},{"v":1.29899627440968,"d":"1.30"},{"v":0.377397293065708,"d":"0.38"},{"v":0.730501558216806,"d":"0.73"},1,"up","no"]
[101337,0,"chr19","+",19516225,19528198,"ENST00000507754",5,521,"ENSG00000186010","NDUFA13","GO:0003954(NADH dehydrogenase activity);GO:0005515(protein binding);GO:0005524(ATP binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0005739(mitochondrion);GO:0005743(mitochondrial inner membrane);GO:0005746(mitochondrial respirasome);GO:0005747(mitochondrial respiratory chain complex I);GO:0006120(mitochondrial electron transport, NADH to ubiquinone);GO:0006915(apoptotic process);GO:0008137(NADH dehydrogenase (ubiquinone) activity);GO:0010952(positive regulation of peptidase activity);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0030308(negative regulation of cell growth);GO:0031966(mitochondrial membrane);GO:0032981(mitochondrial respiratory chain complex I assembly);GO:0035458(cellular response to interferon-beta);GO:0043280(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process);GO:0045039(protein insertion into mitochondrial inner membrane);GO:0045732(positive regulation of protein catabolic process);GO:0045892(negative regulation of transcription, DNA-templated);GO:0055114(oxidation-reduction process);GO:0070469(respirasome);GO:0071300(cellular response to retinoic acid);GO:0072593(reactive oxygen species metabolic process);GO:0097190(apoptotic signaling pathway);GO:0097191(extrinsic apoptotic signaling pathway);GO:2001243(negative regulation of intrinsic apoptotic signaling pathway)","00190(Oxidative phosphorylation);04714(Thermogenesis);04723(Retrograde endocannabinoid signaling);04932(Non-alcoholic fatty liver disease (NAFLD));05010(Alzheimer disease);05012(Parkinson disease);05016(Huntington disease)","K11353","NA","NADH:ubiquinone oxidoreductase subunit A13 [Source:HGNC Symbol;Acc:HGNC:17194]",{"v":58.710915,"d":"58.71"},{"v":54.843552,"d":"54.84"},{"v":55.461521,"d":"55.46"},{"v":40.486217,"d":"40.49"},{"v":45.527843,"d":"45.53"},{"v":55.104134,"d":"55.10"},{"v":1.19769097952033,"d":"1.20"},{"v":0.260255721296397,"d":"0.26"},{"v":0.733090898133918,"d":"0.73"},1,"up","no"]
[166309,0,"chr5","-",179616874,179618301,"ENST00000523921",5,584,"ENSG00000169045","HNRNPH1","GO:0000398(mRNA splicing, via spliceosome);GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005681(spliceosomal complex);GO:0005829(cytosol);GO:0006396(RNA processing);GO:0006397(mRNA processing);GO:0008266(poly(U) RNA binding);GO:0008380(RNA splicing);GO:0008543(fibroblast growth factor receptor signaling pathway);GO:0016020(membrane);GO:0016070(RNA metabolic process);GO:0043484(regulation of RNA splicing);GO:0071013(catalytic step 2 spliceosome)","NA","K12898","NA","heterogeneous nuclear ribonucleoprotein H1 [Source:HGNC Symbol;Acc:HGNC:5041]",{"v":4.273393,"d":"4.27"},{"v":2.37201,"d":"2.37"},{"v":5.139789,"d":"5.14"},{"v":6.22928,"d":"6.23"},{"v":4.372059,"d":"4.37"},{"v":3.977732,"d":"3.98"},{"v":0.808363715356075,"d":"0.81"},{"v":-0.30692352929377,"d":"-0.31"},{"v":0.737928703401424,"d":"0.74"},1,"down","no"]
[20818,0,"chr10","+",46786674,46811989,"ENST00000580094",9,4294,"ENSG00000204177","BMS1P1","NA","NA","NA","NA","BMS1, ribosome biogenesis factor pseudogene 1 [Source:HGNC Symbol;Acc:HGNC:23649]",{"v":0.334194,"d":"0.33"},{"v":0.364609,"d":"0.36"},{"v":0.578661,"d":"0.58"},{"v":0.289889,"d":"0.29"},{"v":0.284073,"d":"0.28"},{"v":0.425351,"d":"0.43"},{"v":1.2783422211059,"d":"1.28"},{"v":0.354274107490102,"d":"0.35"},{"v":0.740436115140334,"d":"0.74"},1,"up","no"]
[79477,0,"chr17","-",1003527,1012589,"ENST00000572585",5,3776,"ENSG00000159842","ABR","GO:0002692(negative regulation of cellular extravasation);GO:0004674(protein serine/threonine kinase activity);GO:0005085(guanyl-nucleotide exchange factor activity);GO:0005089(Rho guanyl-nucleotide exchange factor activity);GO:0005096(GTPase activator activity);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0006468(protein phosphorylation);GO:0007165(signal transduction);GO:0007186(G protein-coupled receptor signaling pathway);GO:0007264(small GTPase mediated signal transduction);GO:0007420(brain development);GO:0016020(membrane);GO:0030036(actin cytoskeleton organization);GO:0030336(negative regulation of cell migration);GO:0032496(response to lipopolysaccharide);GO:0035023(regulation of Rho protein signal transduction);GO:0035556(intracellular signal transduction);GO:0042472(inner ear morphogenesis);GO:0043065(positive regulation of apoptotic process);GO:0043114(regulation of vascular permeability);GO:0043314(negative regulation of neutrophil degranulation);GO:0043547(positive regulation of GTPase activity);GO:0050728(negative regulation of inflammatory response);GO:0050766(positive regulation of phagocytosis);GO:0050804(modulation of chemical synaptic transmission);GO:0050885(neuromuscular process controlling balance);GO:0051056(regulation of small GTPase mediated signal transduction);GO:0060313(negative regulation of blood vessel remodeling);GO:0098685(Schaffer collateral - CA1 synapse);GO:0098978(glutamatergic synapse);GO:0099092(postsynaptic density, intracellular component)","NA","NA","NA","ABR, RhoGEF and GTPase activating protein [Source:HGNC Symbol;Acc:HGNC:81]",{"v":12.173329,"d":"12.17"},{"v":12.668034,"d":"12.67"},{"v":12.466777,"d":"12.47"},{"v":14.463605,"d":"14.46"},{"v":13.9636,"d":"13.96"},{"v":14.054631,"d":"14.05"},{"v":0.878213926535567,"d":"0.88"},{"v":-0.187355682280693,"d":"-0.19"},{"v":0.742424597490663,"d":"0.74"},1,"down","no"]
[81714,0,"chr17","+",14301081,14349404,"ENST00000360954",2,5369,"ENSG00000125430","HS3ST3B1","GO:0000139(Golgi membrane);GO:0005794(Golgi apparatus);GO:0005887(integral component of plasma membrane);GO:0006024(glycosaminoglycan biosynthetic process);GO:0006477(protein sulfation);GO:0008146(sulfotransferase activity);GO:0008467([heparan sulfate]-glucosamine 3-sulfotransferase 1 activity);GO:0015012(heparan sulfate proteoglycan biosynthetic process);GO:0015015(heparan sulfate proteoglycan biosynthetic process, enzymatic modification);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016740(transferase activity);GO:0033872([heparan sulfate]-glucosamine 3-sulfotransferase 3 activity);GO:0034483(heparan sulfate sulfotransferase activity)","00534(Glycosaminoglycan biosynthesis - heparan sulfate / heparin)","K07809","EC:2.8.2.30","heparan sulfate-glucosamine 3-sulfotransferase 3B1 [Source:HGNC Symbol;Acc:HGNC:5198]",{"v":3.583761,"d":"3.58"},{"v":3.302294,"d":"3.30"},{"v":3.36693,"d":"3.37"},{"v":2.616384,"d":"2.62"},{"v":2.876983,"d":"2.88"},{"v":3.011337,"d":"3.01"},{"v":1.20556635480788,"d":"1.21"},{"v":0.269711059582264,"d":"0.27"},{"v":0.744406733495178,"d":"0.74"},1,"up","no"]
[169635,0,"chr6","-",32845209,32853978,"ENST00000354258",11,2959,"ENSG00000168394","TAP1","GO:0000166(nucleotide binding);GO:0002250(adaptive immune response);GO:0002376(immune system process);GO:0002474(antigen processing and presentation of peptide antigen via MHC class I);GO:0002479(antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent);GO:0005515(protein binding);GO:0005524(ATP binding);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005815(microtubule organizing center);GO:0006952(defense response);GO:0015031(protein transport);GO:0015433(peptide antigen-transporting ATPase activity);GO:0015440(peptide-transporting ATPase activity);GO:0015833(peptide transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016032(viral process);GO:0016887(ATPase activity);GO:0019885(antigen processing and presentation of endogenous peptide antigen via MHC class I);GO:0023029(MHC class Ib protein binding);GO:0030176(integral component of endoplasmic reticulum membrane);GO:0030670(phagocytic vesicle membrane);GO:0033116(endoplasmic reticulum-Golgi intermediate compartment membrane);GO:0042287(MHC protein binding);GO:0042288(MHC class I protein binding);GO:0042605(peptide antigen binding);GO:0042626(ATPase activity, coupled to transmembrane movement of substances);GO:0042803(protein homodimerization activity);GO:0042824(MHC class I peptide loading complex);GO:0042825(TAP complex);GO:0042886(amide transport);GO:0043531(ADP binding);GO:0046967(cytosol to endoplasmic reticulum transport);GO:0046978(TAP1 binding);GO:0046979(TAP2 binding);GO:0055085(transmembrane transport);GO:1904680(peptide transmembrane transporter activity);GO:1990668(vesicle fusion with endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membrane)","02010(ABC transporters);04145(Phagosome);04612(Antigen processing and presentation);05163(Human cytomegalovirus infection);05168(Herpes simplex virus 1 infection);05169(Epstein-Barr virus infection);05170(Human immunodeficiency virus 1 infection);05340(Primary immunodeficiency)","K05653","NA","transporter 1, ATP binding cassette subfamily B member [Source:HGNC Symbol;Acc:HGNC:43]",{"v":17.515175,"d":"17.52"},{"v":15.215172,"d":"15.22"},{"v":16.608526,"d":"16.61"},{"v":16.078449,"d":"16.08"},{"v":19.416344,"d":"19.42"},{"v":20.632011,"d":"20.63"},{"v":0.879060795979048,"d":"0.88"},{"v":-0.185965149058629,"d":"-0.19"},{"v":0.746407201829412,"d":"0.75"},1,"down","no"]
[186347,0,"chr8","+",9002804,9033339,"ENST00000250263",7,4615,"ENSG00000104626","ERI1","GO:0000175(3'-5'-exoribonuclease activity);GO:0000467(exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA));GO:0000738(DNA catabolic process, exonucleolytic);GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0004518(nuclease activity);GO:0004527(exonuclease activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005730(nucleolus);GO:0005737(cytoplasm);GO:0006364(rRNA processing);GO:0008408(3'-5' exonuclease activity);GO:0016787(hydrolase activity);GO:0019843(rRNA binding);GO:0031047(gene silencing by RNA);GO:0031125(rRNA 3'-end processing);GO:0043022(ribosome binding);GO:0046872(metal ion binding);GO:0071204(histone pre-mRNA 3'end processing complex);GO:0071207(histone pre-mRNA stem-loop binding);GO:0090305(nucleic acid phosphodiester bond hydrolysis)","NA","K18416","EC:3.1.-.-","exoribonuclease 1 [Source:HGNC Symbol;Acc:HGNC:23994]",{"v":3.417103,"d":"3.42"},{"v":3.538342,"d":"3.54"},{"v":3.427219,"d":"3.43"},{"v":3.057632,"d":"3.06"},{"v":3.076987,"d":"3.08"},{"v":2.465825,"d":"2.47"},{"v":1.20722418516997,"d":"1.21"},{"v":0.271693613789757,"d":"0.27"},{"v":0.751263167854543,"d":"0.75"},1,"up","no"]
[171149,0,"chr6","-",49430360,49463253,"ENST00000274813",13,3811,"ENSG00000146085","MMUT","GO:0003824(catalytic activity);GO:0003924(GTPase activity);GO:0004494(methylmalonyl-CoA mutase activity);GO:0005515(protein binding);GO:0005739(mitochondrion);GO:0005759(mitochondrial matrix);GO:0009235(cobalamin metabolic process);GO:0009791(post-embryonic development);GO:0016853(isomerase activity);GO:0016866(intramolecular transferase activity);GO:0019626(short-chain fatty acid catabolic process);GO:0031419(cobalamin binding);GO:0042802(identical protein binding);GO:0042803(protein homodimerization activity);GO:0043547(positive regulation of GTPase activity);GO:0046872(metal ion binding);GO:0050667(homocysteine metabolic process);GO:0072341(modified amino acid binding)","00280(Valine, leucine and isoleucine degradation);00630(Glyoxylate and dicarboxylate metabolism);00640(Propanoate metabolism)","K01847","EC:5.4.99.2","methylmalonyl-CoA mutase [Source:HGNC Symbol;Acc:HGNC:7526]",{"v":11.044051,"d":"11.04"},{"v":11.995701,"d":"12.00"},{"v":10.993801,"d":"10.99"},{"v":9.753566,"d":"9.75"},{"v":9.368998,"d":"9.37"},{"v":9.793052,"d":"9.79"},{"v":1.17699560680291,"d":"1.18"},{"v":0.235108935452415,"d":"0.24"},{"v":0.753574231877953,"d":"0.75"},1,"up","no"]
[14249,0,"chr1","-",175945153,176206978,"ENST00000308769",19,2124,"ENSG00000143207","COP1","GO:0000139(Golgi membrane);GO:0004842(ubiquitin-protein transferase activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0010212(response to ionizing radiation);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016567(protein ubiquitination);GO:0016607(nuclear speck);GO:0016740(transferase activity);GO:0031464(Cul4A-RING E3 ubiquitin ligase complex);GO:0032436(positive regulation of proteasomal ubiquitin-dependent protein catabolic process);GO:0043161(proteasome-mediated ubiquitin-dependent protein catabolic process);GO:0043687(post-translational protein modification);GO:0046872(metal ion binding);GO:0061630(ubiquitin protein ligase activity)","04115(p53 signaling pathway);04120(Ubiquitin mediated proteolysis)","K10143","EC:2.3.2.27","COP1, E3 ubiquitin ligase [Source:HGNC Symbol;Acc:HGNC:17440]",{"v":3.817436,"d":"3.82"},{"v":5.000546,"d":"5.00"},{"v":2.455113,"d":"2.46"},{"v":3.012082,"d":"3.01"},{"v":2.516468,"d":"2.52"},{"v":3.573162,"d":"3.57"},{"v":1.2385686341207,"d":"1.24"},{"v":0.308673816393742,"d":"0.31"},{"v":0.755643831650333,"d":"0.76"},1,"up","no"]
[42473,0,"chr12","-",49127782,49131395,"ENST00000336023",4,1627,"ENSG00000123416","TUBA1B","GO:0000166(nucleotide binding);GO:0000226(microtubule cytoskeleton organization);GO:0000278(mitotic cell cycle);GO:0003725(double-stranded RNA binding);GO:0003924(GTPase activity);GO:0005198(structural molecule activity);GO:0005200(structural constituent of cytoskeleton);GO:0005515(protein binding);GO:0005525(GTP binding);GO:0005737(cytoplasm);GO:0005856(cytoskeleton);GO:0005874(microtubule);GO:0005881(cytoplasmic microtubule);GO:0007010(cytoskeleton organization);GO:0007017(microtubule-based process);GO:0015630(microtubule cytoskeleton);GO:0030705(cytoskeleton-dependent intracellular transport);GO:0031625(ubiquitin protein ligase binding);GO:0045121(membrane raft);GO:0051301(cell division);GO:0071353(cellular response to interleukin-4)","04145(Phagosome);04210(Apoptosis);04530(Tight junction);04540(Gap junction);05130(Pathogenic Escherichia coli infection)","K07374","NA","tubulin alpha 1b [Source:HGNC Symbol;Acc:HGNC:18809]",{"v":193.210175,"d":"193.21"},{"v":164.625229,"d":"164.63"},{"v":172.692368,"d":"172.69"},{"v":210.547623,"d":"210.55"},{"v":200.466431,"d":"200.47"},{"v":182.907928,"d":"182.91"},{"v":0.893261721368649,"d":"0.89"},{"v":-0.162845154927112,"d":"-0.16"},{"v":0.75745573261176,"d":"0.76"},1,"down","no"]
[198858,0,"chr9","+",122371024,122395703,"ENST00000614910",11,5020,"ENSG00000095303","PTGS1","GO:0001516(prostaglandin biosynthetic process);GO:0001750(photoreceptor outer segment);GO:0004601(peroxidase activity);GO:0004666(prostaglandin-endoperoxide synthase activity);GO:0005737(cytoplasm);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005794(Golgi apparatus);GO:0006629(lipid metabolic process);GO:0006631(fatty acid metabolic process);GO:0006633(fatty acid biosynthetic process);GO:0006693(prostaglandin metabolic process);GO:0006805(xenobiotic metabolic process);GO:0006954(inflammatory response);GO:0006979(response to oxidative stress);GO:0008217(regulation of blood pressure);GO:0016020(membrane);GO:0016491(oxidoreductase activity);GO:0019371(cyclooxygenase pathway);GO:0020037(heme binding);GO:0031090(organelle membrane);GO:0042127(regulation of cell population proliferation);GO:0043231(intracellular membrane-bounded organelle);GO:0046872(metal ion binding);GO:0051213(dioxygenase activity);GO:0055114(oxidation-reduction process);GO:0070062(extracellular exosome);GO:0098869(cellular oxidant detoxification)","00590(Arachidonic acid metabolism);04611(Platelet activation);04726(Serotonergic synapse);04923(Regulation of lipolysis in adipocytes)","K00509","EC:1.14.99.1","prostaglandin-endoperoxide synthase 1 [Source:HGNC Symbol;Acc:HGNC:9604]",{"v":17.067091,"d":"17.07"},{"v":11.077184,"d":"11.08"},{"v":10.465574,"d":"10.47"},{"v":14.711454,"d":"14.71"},{"v":15.127787,"d":"15.13"},{"v":13.743663,"d":"13.74"},{"v":0.885894363533004,"d":"0.89"},{"v":-0.174793416753886,"d":"-0.17"},{"v":0.759745344301279,"d":"0.76"},1,"down","no"]
[147425,0,"chr3","-",184346199,184361629,"ENST00000636180",21,3019,"ENSG00000114859","CLCN2","GO:0005244(voltage-gated ion channel activity);GO:0005247(voltage-gated chloride channel activity);GO:0005254(chloride channel activity);GO:0005886(plasma membrane);GO:0005887(integral component of plasma membrane);GO:0006811(ion transport);GO:0006821(chloride transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0032347(regulation of aldosterone biosynthetic process);GO:0034220(ion transmembrane transport);GO:0034707(chloride channel complex);GO:0034765(regulation of ion transmembrane transport);GO:0055085(transmembrane transport);GO:0060041(retina development in camera-type eye);GO:0060689(cell differentiation involved in salivary gland development);GO:1902476(chloride transmembrane transport)","04978(Mineral absorption)","K05011","NA","chloride voltage-gated channel 2 [Source:HGNC Symbol;Acc:HGNC:2020]",{"v":0.556183,"d":"0.56"},{"v":0.154694,"d":"0.15"},{"v":0.35155,"d":"0.35"},{"v":0.507433,"d":"0.51"},{"v":0.281596,"d":"0.28"},{"v":0.509743,"d":"0.51"},{"v":0.818024256759462,"d":"0.82"},{"v":-0.289784471050746,"d":"-0.29"},{"v":0.763993435628365,"d":"0.76"},1,"down","no"]
[179581,0,"chr7","+",66075874,66092931,"ENST00000395332",16,1622,"ENSG00000126522","ASL","GO:0000050(urea cycle);GO:0003824(catalytic activity);GO:0004056(argininosuccinate lyase activity);GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0006526(arginine biosynthetic process);GO:0008652(cellular amino acid biosynthetic process);GO:0016829(lyase activity);GO:0042450(arginine biosynthetic process via ornithine);GO:0042802(identical protein binding);GO:0070062(extracellular exosome)","00220(Arginine biosynthesis);00250(Alanine, aspartate and glutamate metabolism)","NA","NA","argininosuccinate lyase [Source:HGNC Symbol;Acc:HGNC:746]",{"v":0.246214,"d":"0.25"},{"v":0.788267,"d":"0.79"},{"v":2.712858,"d":"2.71"},{"v":1.411285,"d":"1.41"},{"v":0.173743,"d":"0.17"},{"v":1.271477,"d":"1.27"},{"v":1.31186152308503,"d":"1.31"},{"v":0.391615440609747,"d":"0.39"},{"v":0.766170174646624,"d":"0.77"},1,"up","no"]
[164682,0,"chr5","+",154190730,154389581,"ENST00000425427",7,4344,"ENSG00000164574","GALNT10","GO:0000139(Golgi membrane);GO:0004653(polypeptide N-acetylgalactosaminyltransferase activity);GO:0005794(Golgi apparatus);GO:0006486(protein glycosylation);GO:0006493(protein O-linked glycosylation);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016266(O-glycan processing);GO:0016740(transferase activity);GO:0016757(transferase activity, transferring glycosyl groups);GO:0030246(carbohydrate binding);GO:0046872(metal ion binding)","00512(Mucin type O-glycan biosynthesis)","K00710","EC:2.4.1.41","polypeptide N-acetylgalactosaminyltransferase 10 [Source:HGNC Symbol;Acc:HGNC:19873]",{"v":0.24308,"d":"0.24"},{"v":0.254441,"d":"0.25"},{"v":0.137442,"d":"0.14"},{"v":0.133302,"d":"0.13"},{"v":0.255643,"d":"0.26"},{"v":0.105918,"d":"0.11"},{"v":1.28310865835595,"d":"1.28"},{"v":0.359643348318124,"d":"0.36"},{"v":0.768295908422019,"d":"0.77"},1,"up","no"]
[85479,0,"chr17","+",41688935,41690999,"ENST00000469308",4,815,"ENSG00000173812","EIF1","GO:0003723(RNA binding);GO:0003743(translation initiation factor activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0006412(translation);GO:0006413(translational initiation);GO:0006446(regulation of translational initiation);GO:0008135(translation factor activity, RNA binding);GO:0009048(dosage compensation by inactivation of X chromosome);GO:0016282(eukaryotic 43S preinitiation complex);GO:0043024(ribosomal small subunit binding)","03013(RNA transport)","K03113","NA","eukaryotic translation initiation factor 1 [Source:HGNC Symbol;Acc:HGNC:3249]",{"v":2.753965,"d":"2.75"},{"v":2.902554,"d":"2.90"},{"v":4.805296,"d":"4.81"},{"v":4.153801,"d":"4.15"},{"v":4.666022,"d":"4.67"},{"v":3.707847,"d":"3.71"},{"v":0.835096630099612,"d":"0.84"},{"v":-0.25998495155256,"d":"-0.26"},{"v":0.770411482423665,"d":"0.77"},1,"down","no"]
[100434,0,"chr19","-",16517896,16542415,"ENST00000198939",17,4084,"ENSG00000085872","CHERP","GO:0000398(mRNA splicing, via spliceosome);GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0005515(protein binding);GO:0005623(cell);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0005783(endoplasmic reticulum);GO:0006396(RNA processing);GO:0006874(cellular calcium ion homeostasis);GO:0007399(nervous system development);GO:0008285(negative regulation of cell population proliferation);GO:0016020(membrane);GO:0033017(sarcoplasmic reticulum membrane);GO:0044325(ion channel binding);GO:0048471(perinuclear region of cytoplasm);GO:0051209(release of sequestered calcium ion into cytosol);GO:0070886(positive regulation of calcineurin-NFAT signaling cascade)","03040(Spliceosome)","K12841","NA","calcium homeostasis endoplasmic reticulum protein [Source:HGNC Symbol;Acc:HGNC:16930]",{"v":1.56047,"d":"1.56"},{"v":0.131964,"d":"0.13"},{"v":1.947094,"d":"1.95"},{"v":1.018655,"d":"1.02"},{"v":1.645068,"d":"1.65"},{"v":1.795777,"d":"1.80"},{"v":0.816129162462159,"d":"0.82"},{"v":-0.293130600414378,"d":"-0.29"},{"v":0.77229520108484,"d":"0.77"},1,"down","no"]
[111071,0,"chr2","+",30146941,30160533,"ENST00000379519",4,2499,"ENSG00000119801","YPEL5","GO:0000151(ubiquitin ligase complex);GO:0000922(spindle pole);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005813(centrosome);GO:0005815(microtubule organizing center);GO:0005856(cytoskeleton);GO:0008283(cell population proliferation);GO:0030496(midbody);GO:0043312(neutrophil degranulation);GO:0046872(metal ion binding);GO:0097431(mitotic spindle pole);GO:1904724(tertiary granule lumen);GO:1904813(ficolin-1-rich granule lumen)","NA","NA","NA","yippee like 5 [Source:HGNC Symbol;Acc:HGNC:18329]",{"v":2.541891,"d":"2.54"},{"v":2.562517,"d":"2.56"},{"v":3.65746,"d":"3.66"},{"v":2.228769,"d":"2.23"},{"v":2.218637,"d":"2.22"},{"v":2.736763,"d":"2.74"},{"v":1.21960772359336,"d":"1.22"},{"v":0.286417191861216,"d":"0.29"},{"v":0.77431149800951,"d":"0.77"},1,"up","no"]
[153704,0,"chr4","-",102797247,102825860,"ENST00000350435",7,711,"ENSG00000109332","UBE2D3","GO:0000122(negative regulation of transcription by RNA polymerase II);GO:0000151(ubiquitin ligase complex);GO:0000166(nucleotide binding);GO:0000209(protein polyubiquitination);GO:0002756(MyD88-independent toll-like receptor signaling pathway);GO:0004842(ubiquitin-protein transferase activity);GO:0005515(protein binding);GO:0005524(ATP binding);GO:0005654(nucleoplasm);GO:0005768(endosome);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0006281(DNA repair);GO:0006464(cellular protein modification process);GO:0006511(ubiquitin-dependent protein catabolic process);GO:0006513(protein monoubiquitination);GO:0006625(protein targeting to peroxisome);GO:0006915(apoptotic process);GO:0006974(cellular response to DNA damage stimulus);GO:0010008(endosome membrane);GO:0016020(membrane);GO:0016567(protein ubiquitination);GO:0016740(transferase activity);GO:0030509(BMP signaling pathway);GO:0031625(ubiquitin protein ligase binding);GO:0035666(TRIF-dependent toll-like receptor signaling pathway);GO:0043161(proteasome-mediated ubiquitin-dependent protein catabolic process);GO:0051865(protein autoubiquitination);GO:0061631(ubiquitin conjugating enzyme activity);GO:0070062(extracellular exosome);GO:0070936(protein K48-linked ubiquitination);GO:0070979(protein K11-linked ubiquitination);GO:0071276(cellular response to cadmium ion);GO:0071288(cellular response to mercury ion);GO:1903955(positive regulation of protein targeting to mitochondrion)","04120(Ubiquitin mediated proteolysis);04141(Protein processing in endoplasmic reticulum)","K06689","EC:2.3.2.23","ubiquitin conjugating enzyme E2 D3 [Source:HGNC Symbol;Acc:HGNC:12476]",{"v":0.43083,"d":"0.43"},{"v":5.815691,"d":"5.82"},{"v":0.411594,"d":"0.41"},{"v":3.020803,"d":"3.02"},{"v":1.205974,"d":"1.21"},{"v":0.843866,"d":"0.84"},{"v":1.31307114304833,"d":"1.31"},{"v":0.392945084503821,"d":"0.39"},{"v":0.778782041786405,"d":"0.78"},1,"up","no"]
[55274,0,"chr14","-",24239682,24242613,"ENST00000558566",4,1874,"ENSG00000092330","TINF2","GO:0000781(chromosome, telomeric region);GO:0000783(nuclear telomere cap complex);GO:0000784(nuclear chromosome, telomeric region);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005694(chromosome);GO:0010370(perinucleolar chromocenter);GO:0010836(negative regulation of protein ADP-ribosylation);GO:0016233(telomere capping);GO:0016363(nuclear matrix);GO:0016604(nuclear body);GO:0032202(telomere assembly);GO:0032211(negative regulation of telomere maintenance via telomerase);GO:0042162(telomeric DNA binding);GO:0050680(negative regulation of epithelial cell proliferation);GO:0070187(shelterin complex);GO:0070198(protein localization to chromosome, telomeric region);GO:1904356(regulation of telomere maintenance via telomere lengthening)","NA","K11112","NA","TERF1 interacting nuclear factor 2 [Source:HGNC Symbol;Acc:HGNC:11824]",{"v":1.683596,"d":"1.68"},{"v":2.445976,"d":"2.45"},{"v":0.649834,"d":"0.65"},{"v":0.406948,"d":"0.41"},{"v":2.845581,"d":"2.85"},{"v":0.539014,"d":"0.54"},{"v":1.26054379443936,"d":"1.26"},{"v":0.334046241895716,"d":"0.33"},{"v":0.781070183059133,"d":"0.78"},1,"up","no"]
[30641,0,"chr11","-",59130133,59142755,"ENST00000501817",5,2110,"ENSG00000245571","FAM111A-DT","NA","NA","NA","NA","FAM111A divergent transcript [Source:HGNC Symbol;Acc:HGNC:53752]",{"v":0.99365,"d":"0.99"},{"v":1.070456,"d":"1.07"},{"v":0.844704,"d":"0.84"},{"v":0.89206,"d":"0.89"},{"v":1.311702,"d":"1.31"},{"v":1.252488,"d":"1.25"},{"v":0.841608679927667,"d":"0.84"},{"v":-0.248778510951033,"d":"-0.25"},{"v":0.783081915358673,"d":"0.78"},1,"down","no"]
[78449,0,"chr16","+",85801202,85806967,"ENST00000564648",3,1235,"ENSG00000131143","COX4I1","GO:0004129(cytochrome-c oxidase activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005739(mitochondrion);GO:0005743(mitochondrial inner membrane);GO:0005751(mitochondrial respiratory chain complex IV);GO:0006091(generation of precursor metabolites and energy);GO:0006123(mitochondrial electron transport, cytochrome c to oxygen);GO:0007584(response to nutrient);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0022900(electron transport chain);GO:0031966(mitochondrial membrane);GO:1902600(proton transmembrane transport)","00190(Oxidative phosphorylation);04260(Cardiac muscle contraction);04714(Thermogenesis);04932(Non-alcoholic fatty liver disease (NAFLD));05010(Alzheimer disease);05012(Parkinson disease);05016(Huntington disease)","NA","NA","cytochrome c oxidase subunit 4I1 [Source:HGNC Symbol;Acc:HGNC:2265]",{"v":4.988283,"d":"4.99"},{"v":4.609323,"d":"4.61"},{"v":5.690441,"d":"5.69"},{"v":3.789311,"d":"3.79"},{"v":5.009381,"d":"5.01"},{"v":9.153085,"d":"9.15"},{"v":0.851617474971976,"d":"0.85"},{"v":-0.231722541061522,"d":"-0.23"},{"v":0.78475757941306,"d":"0.78"},1,"down","no"]
[51724,0,"chr13","+",48975912,49209779,"ENST00000492622",26,6286,"ENSG00000102531","FNDC3A","GO:0000139(Golgi membrane);GO:0001669(acrosomal vesicle);GO:0003723(RNA binding);GO:0005515(protein binding);GO:0005794(Golgi apparatus);GO:0005829(cytosol);GO:0007286(spermatid development);GO:0009566(fertilization);GO:0012506(vesicle membrane);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0031410(cytoplasmic vesicle);GO:0060009(Sertoli cell development);GO:0098609(cell-cell adhesion)","NA","NA","NA","fibronectin type III domain containing 3A [Source:HGNC Symbol;Acc:HGNC:20296]",{"v":0.724326,"d":"0.72"},{"v":0.625834,"d":"0.63"},{"v":0.940352,"d":"0.94"},{"v":0.914296,"d":"0.91"},{"v":1.064993,"d":"1.06"},{"v":0.70187,"d":"0.70"},{"v":0.854299204187443,"d":"0.85"},{"v":-0.227186656426084,"d":"-0.23"},{"v":0.786520111183741,"d":"0.79"},1,"down","no"]
[68993,0,"chr15","+",101751032,101773472,"ENST00000561463",4,15043,"ENSG00000259660","DNM1P47","NA","NA","NA","NA","dynamin 1 pseudogene 47 [Source:HGNC Symbol;Acc:HGNC:35200]",{"v":0.112916,"d":"0.11"},{"v":0.106645,"d":"0.11"},{"v":0.152413,"d":"0.15"},{"v":0.161073,"d":"0.16"},{"v":0.10792,"d":"0.11"},{"v":0.170267,"d":"0.17"},{"v":0.846819651231617,"d":"0.85"},{"v":-0.239873346083374,"d":"-0.24"},{"v":0.790876618614162,"d":"0.79"},1,"down","no"]
[195697,0,"chr9","+",36190921,36212059,"ENST00000345519",5,1078,"ENSG00000122705","CLTA","GO:0003674(molecular_function);GO:0005198(structural molecule activity);GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0005819(spindle);GO:0005829(cytosol);GO:0005856(cytoskeleton);GO:0005886(plasma membrane);GO:0005905(clathrin-coated pit);GO:0006886(intracellular protein transport);GO:0006897(endocytosis);GO:0007049(cell cycle);GO:0016020(membrane);GO:0016192(vesicle-mediated transport);GO:0019886(antigen processing and presentation of exogenous peptide antigen via MHC class II);GO:0030118(clathrin coat);GO:0030125(clathrin vesicle coat);GO:0030130(clathrin coat of trans-Golgi network vesicle);GO:0030132(clathrin coat of coated pit);GO:0030136(clathrin-coated vesicle);GO:0030659(cytoplasmic vesicle membrane);GO:0030672(synaptic vesicle membrane);GO:0031410(cytoplasmic vesicle);GO:0032050(clathrin heavy chain binding);GO:0032588(trans-Golgi network membrane);GO:0032802(low-density lipoprotein particle receptor catabolic process);GO:0034383(low-density lipoprotein particle clearance);GO:0036020(endolysosome membrane);GO:0042277(peptide binding);GO:0044877(protein-containing complex binding);GO:0045334(clathrin-coated endocytic vesicle);GO:0048268(clathrin coat assembly);GO:0051020(GTPase binding);GO:0051301(cell division);GO:0061024(membrane organization);GO:0071439(clathrin complex);GO:0072583(clathrin-dependent endocytosis);GO:0098835(presynaptic endocytic zone membrane);GO:0099631(postsynaptic endocytic zone cytoplasmic component)","04142(Lysosome);04144(Endocytosis);04721(Synaptic vesicle cycle);04961(Endocrine and other factor-regulated calcium reabsorption);05016(Huntington disease);05100(Bacterial invasion of epithelial cells)","NA","NA","clathrin light chain A [Source:HGNC Symbol;Acc:HGNC:2090]",{"v":88.473099,"d":"88.47"},{"v":138.750595,"d":"138.75"},{"v":53.303169,"d":"53.30"},{"v":141.026978,"d":"141.03"},{"v":123.955971,"d":"123.96"},{"v":47.30777,"d":"47.31"},{"v":0.89828754404962,"d":"0.90"},{"v":-0.154750765765097,"d":"-0.15"},{"v":0.792573957405359,"d":"0.79"},1,"down","no"]
[76877,0,"chr16","-",69120461,69132578,"ENST00000522091",3,863,"ENSG00000168802","CHTF8","GO:0003677(DNA binding);GO:0003689(DNA clamp loader activity);GO:0005634(nucleus);GO:0006260(DNA replication);GO:0007049(cell cycle);GO:0007064(mitotic sister chromatid cohesion);GO:0031390(Ctf18 RFC-like complex);GO:0043142(single-stranded DNA-dependent ATPase activity);GO:1900264(positive regulation of DNA-directed DNA polymerase activity)","NA","K11270","NA","chromosome transmission fidelity factor 8 [Source:HGNC Symbol;Acc:HGNC:24353]",{"v":0.803573,"d":"0.80"},{"v":0.874085,"d":"0.87"},{"v":0.976779,"d":"0.98"},{"v":1.228509,"d":"1.23"},{"v":0.695672,"d":"0.70"},{"v":1.285074,"d":"1.29"},{"v":0.827119378173439,"d":"0.83"},{"v":-0.273832526229024,"d":"-0.27"},{"v":0.794138970205529,"d":"0.79"},1,"down","no"]
[146141,0,"chr3","+",161221324,161238191,"ENST00000463518",8,1077,"ENSG00000169251","NMD3","GO:0000055(ribosomal large subunit export from nucleus);GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005730(nucleolus);GO:0005737(cytoplasm);GO:0015031(protein transport);GO:0016020(membrane);GO:0030674(protein binding, bridging);GO:0032092(positive regulation of protein binding);GO:0043023(ribosomal large subunit binding);GO:1902680(positive regulation of RNA biosynthetic process);GO:1904751(positive regulation of protein localization to nucleolus)","03008(Ribosome biogenesis in eukaryotes);03013(RNA transport)","K07562","NA","NMD3 ribosome export adaptor [Source:HGNC Symbol;Acc:HGNC:24250]",{"v":1.05216,"d":"1.05"},{"v":1.727322,"d":"1.73"},{"v":1.910451,"d":"1.91"},{"v":1.876778,"d":"1.88"},{"v":0.408171,"d":"0.41"},{"v":1.51367,"d":"1.51"},{"v":1.23464158948291,"d":"1.23"},{"v":0.304092295153407,"d":"0.30"},{"v":0.795888636091057,"d":"0.80"},1,"up","no"]
[154582,0,"chr4","+",122309365,122362750,"ENST00000438707",30,5528,"ENSG00000138688","KIAA1109","GO:0001558(regulation of cell growth);GO:0005515(protein binding);GO:0005634(nucleus);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0030856(regulation of epithelial cell differentiation);GO:0048488(synaptic vesicle endocytosis);GO:0098793(presynapse)","NA","NA","NA","KIAA1109 [Source:HGNC Symbol;Acc:HGNC:26953]",{"v":0.57882,"d":"0.58"},{"v":2.45123,"d":"2.45"},{"v":1.074566,"d":"1.07"},{"v":1.861631,"d":"1.86"},{"v":1.893614,"d":"1.89"},{"v":0.989573,"d":"0.99"},{"v":0.865073433796618,"d":"0.87"},{"v":-0.209105490372111,"d":"-0.21"},{"v":0.797515363348259,"d":"0.80"},1,"down","no"]
[138719,0,"chr3","+",42160169,42225889,"ENST00000396175",15,5033,"ENSG00000182606","TRAK1","GO:0005102(signaling receptor binding);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005739(mitochondrion);GO:0005768(endosome);GO:0005769(early endosome);GO:0005938(cell cortex);GO:0006357(regulation of transcription by RNA polymerase II);GO:0006493(protein O-linked glycosylation);GO:0006605(protein targeting);GO:0008089(anterograde axonal transport);GO:0008104(protein localization);GO:0008333(endosome to lysosome transport);GO:0016020(membrane);GO:0017022(myosin binding);GO:0019896(axonal transport of mitochondrion);GO:0022008(neurogenesis);GO:0030425(dendrite);GO:0030911(TPR domain binding);GO:0031410(cytoplasmic vesicle);GO:0031966(mitochondrial membrane);GO:0032839(dendrite cytoplasm);GO:0044295(axonal growth cone);GO:0047496(vesicle transport along microtubule);GO:0048311(mitochondrion distribution);GO:0048471(perinuclear region of cytoplasm);GO:0048813(dendrite morphogenesis);GO:0050772(positive regulation of axonogenesis);GO:0050811(GABA receptor binding);GO:0098957(anterograde axonal transport of mitochondrion);GO:1904115(axon cytoplasm)","NA","K15369","NA","trafficking kinesin protein 1 [Source:HGNC Symbol;Acc:HGNC:29947]",{"v":2.790357,"d":"2.79"},0,{"v":0.054134,"d":"0.05"},0,0,{"v":1.858983,"d":"1.86"},{"v":1.53013287372719,"d":"1.53"},{"v":0.613656939155694,"d":"0.61"},{"v":0.801814733511729,"d":"0.80"},1,"up","no"]
[96537,0,"chr19","+",1241746,1244825,"ENST00000395633",5,704,"ENSG00000099624","ATP5F1D","GO:0000275(mitochondrial proton-transporting ATP synthase complex, catalytic core F(1));GO:0005215(transporter activity);GO:0005524(ATP binding);GO:0005739(mitochondrion);GO:0005743(mitochondrial inner membrane);GO:0005753(mitochondrial proton-transporting ATP synthase complex);GO:0005759(mitochondrial matrix);GO:0006119(oxidative phosphorylation);GO:0006754(ATP biosynthetic process);GO:0006811(ion transport);GO:0009060(aerobic respiration);GO:0015986(ATP synthesis coupled proton transport);GO:0016020(membrane);GO:0016887(ATPase activity);GO:0022857(transmembrane transporter activity);GO:0033615(mitochondrial proton-transporting ATP synthase complex assembly);GO:0042407(cristae formation);GO:0042776(mitochondrial ATP synthesis coupled proton transport);GO:0043531(ADP binding);GO:0045261(proton-transporting ATP synthase complex, catalytic core F(1));GO:0046688(response to copper ion);GO:0046933(proton-transporting ATP synthase activity, rotational mechanism);GO:0099132(ATP hydrolysis coupled cation transmembrane transport)","00190(Oxidative phosphorylation);04714(Thermogenesis);05010(Alzheimer disease);05012(Parkinson disease);05016(Huntington disease)","NA","NA","ATP synthase F1 subunit delta [Source:HGNC Symbol;Acc:HGNC:837]",{"v":5.372754,"d":"5.37"},{"v":8.59647,"d":"8.60"},{"v":5.141695,"d":"5.14"},{"v":8.912325,"d":"8.91"},{"v":7.40163,"d":"7.40"},{"v":5.736478,"d":"5.74"},{"v":0.866691325290529,"d":"0.87"},{"v":-0.206409830119414,"d":"-0.21"},{"v":0.803695787057843,"d":"0.80"},1,"down","no"]
[23006,0,"chr10","+",91410345,91514761,"ENST00000298068",21,4802,"ENSG00000165338","HECTD2","GO:0000209(protein polyubiquitination);GO:0004842(ubiquitin-protein transferase activity);GO:0005829(cytosol);GO:0016567(protein ubiquitination);GO:0016740(transferase activity)","NA","K12232","EC:2.3.2.26","HECT domain E3 ubiquitin protein ligase 2 [Source:HGNC Symbol;Acc:HGNC:26736]",{"v":3.791112,"d":"3.79"},{"v":4.373995,"d":"4.37"},{"v":4.562929,"d":"4.56"},{"v":3.390606,"d":"3.39"},{"v":3.904146,"d":"3.90"},{"v":3.736577,"d":"3.74"},{"v":1.1538080316524,"d":"1.15"},{"v":0.206403211140095,"d":"0.21"},{"v":0.805505268528351,"d":"0.81"},1,"up","no"]
[98890,0,"chr19","+",10718079,10831047,"ENST00000585892",21,2774,"ENSG00000079805","DNM2","GO:0000086(G2/M transition of mitotic cell cycle);GO:0000139(Golgi membrane);GO:0000166(nucleotide binding);GO:0001891(phagocytic cup);GO:0001917(photoreceptor inner segment);GO:0002031(G protein-coupled receptor internalization);GO:0003281(ventricular septum development);GO:0003924(GTPase activity);GO:0005515(protein binding);GO:0005525(GTP binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005768(endosome);GO:0005794(Golgi apparatus);GO:0005802(trans-Golgi network);GO:0005813(centrosome);GO:0005829(cytosol);GO:0005856(cytoskeleton);GO:0005874(microtubule);GO:0005886(plasma membrane);GO:0005905(clathrin-coated pit);GO:0005925(focal adhesion);GO:0006355(regulation of transcription, DNA-templated);GO:0006893(Golgi to plasma membrane transport);GO:0006897(endocytosis);GO:0006898(receptor-mediated endocytosis);GO:0006909(phagocytosis);GO:0007165(signal transduction);GO:0007283(spermatogenesis);GO:0008017(microtubule binding);GO:0009416(response to light stimulus);GO:0010592(positive regulation of lamellipodium assembly);GO:0014069(postsynaptic density);GO:0016020(membrane);GO:0016185(synaptic vesicle budding from presynaptic endocytic zone membrane);GO:0016787(hydrolase activity);GO:0017124(SH3 domain binding);GO:0019886(antigen processing and presentation of exogenous peptide antigen via MHC class II);GO:0019899(enzyme binding);GO:0019901(protein kinase binding);GO:0030027(lamellipodium);GO:0030054(cell junction);GO:0030424(axon);GO:0030426(growth cone);GO:0030496(midbody);GO:0030512(negative regulation of transforming growth factor beta receptor signaling pathway);GO:0030516(regulation of axon extension);GO:0030666(endocytic vesicle membrane);GO:0030670(phagocytic vesicle membrane);GO:0031410(cytoplasmic vesicle);GO:0031623(receptor internalization);GO:0031749(D2 dopamine receptor binding);GO:0032587(ruffle membrane);GO:0032991(protein-containing complex);GO:0033572(transferrin transport);GO:0035020(regulation of Rac protein signal transduction);GO:0035904(aorta development);GO:0036312(phosphatidylinositol 3-kinase regulatory subunit binding);GO:0042220(response to cocaine);GO:0042995(cell projection);GO:0043065(positive regulation of apoptotic process);GO:0043197(dendritic spine);GO:0044327(dendritic spine head);GO:0044351(macropinocytosis);GO:0044877(protein-containing complex binding);GO:0045202(synapse);GO:0045211(postsynaptic membrane);GO:0045334(clathrin-coated endocytic vesicle);GO:0045429(positive regulation of nitric oxide biosynthetic process);GO:0045807(positive regulation of endocytosis);GO:0045893(positive regulation of transcription, DNA-templated);GO:0048471(perinuclear region of cytoplasm);GO:0048488(synaptic vesicle endocytosis);GO:0048489(synaptic vesicle transport);GO:0048812(neuron projection morphogenesis);GO:0050699(WW domain binding);GO:0050766(positive regulation of phagocytosis);GO:0050803(regulation of synapse structure or activity);GO:0050998(nitric-oxide synthase binding);GO:0050999(regulation of nitric-oxide synthase activity);GO:0060976(coronary vasculature development);GO:0061024(membrane organization);GO:0070062(extracellular exosome);GO:0071245(cellular response to carbon monoxide);GO:0071481(cellular response to X-ray);GO:0071732(cellular response to nitric oxide);GO:0098793(presynapse);GO:0098844(postsynaptic endocytic zone membrane);GO:0098884(postsynaptic neurotransmitter receptor internalization);GO:0098978(glutamatergic synapse);GO:0099092(postsynaptic density, intracellular component);GO:1900026(positive regulation of substrate adhesion-dependent cell spreading);GO:1902856(negative regulation of non-motile cilium assembly);GO:1903351(cellular response to dopamine);GO:1903358(regulation of Golgi organization);GO:1903408(positive regulation of sodium:potassium-exchanging ATPase activity);GO:1903526(negative regulation of membrane tubulation);GO:2000370(positive regulation of clathrin-dependent endocytosis)","04072(Phospholipase D signaling pathway);04144(Endocytosis);04666(Fc gamma R-mediated phagocytosis);04721(Synaptic vesicle cycle);04961(Endocrine and other factor-regulated calcium reabsorption);05100(Bacterial invasion of epithelial cells)","K01528","EC:3.6.5.5","dynamin 2 [Source:HGNC Symbol;Acc:HGNC:2974]",{"v":1.862294,"d":"1.86"},{"v":1.566476,"d":"1.57"},{"v":1.517838,"d":"1.52"},{"v":2.551346,"d":"2.55"},{"v":1.509287,"d":"1.51"},{"v":1.63666,"d":"1.64"},{"v":0.86823830194445,"d":"0.87"},{"v":-0.203837027046102,"d":"-0.20"},{"v":0.807123157906212,"d":"0.81"},1,"down","no"]
[80227,0,"chr17","-",4898085,4934438,"ENST00000649830",11,2293,"ENSG00000108556","CHRNE","GO:0004888(transmembrane signaling receptor activity);GO:0005216(ion channel activity);GO:0005230(extracellular ligand-gated ion channel activity);GO:0005886(plasma membrane);GO:0005887(integral component of plasma membrane);GO:0005892(acetylcholine-gated channel complex);GO:0006811(ion transport);GO:0006936(muscle contraction);GO:0007165(signal transduction);GO:0007268(chemical synaptic transmission);GO:0007271(synaptic transmission, cholinergic);GO:0007274(neuromuscular synaptic transmission);GO:0008324(cation transmembrane transporter activity);GO:0015464(acetylcholine receptor activity);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0022848(acetylcholine-gated cation-selective channel activity);GO:0030054(cell junction);GO:0031594(neuromuscular junction);GO:0034220(ion transmembrane transport);GO:0035094(response to nicotine);GO:0042166(acetylcholine binding);GO:0042391(regulation of membrane potential);GO:0043005(neuron projection);GO:0045202(synapse);GO:0045211(postsynaptic membrane);GO:0050877(nervous system process);GO:0060078(regulation of postsynaptic membrane potential);GO:0060079(excitatory postsynaptic potential);GO:0098655(cation transmembrane transport);GO:0099060(integral component of postsynaptic specialization membrane);GO:1904315(transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential)","04080(Neuroactive ligand-receptor interaction)","NA","NA","cholinergic receptor nicotinic epsilon subunit [Source:HGNC Symbol;Acc:HGNC:1966]",{"v":1.138702,"d":"1.14"},{"v":0.878503,"d":"0.88"},{"v":1.165917,"d":"1.17"},{"v":1.11674,"d":"1.12"},{"v":0.755596,"d":"0.76"},{"v":0.773089,"d":"0.77"},{"v":1.20325543154692,"d":"1.20"},{"v":0.266942935705124,"d":"0.27"},{"v":0.809123976883727,"d":"0.81"},1,"up","no"]
[188325,0,"chr8","+",37796906,37844896,"ENST00000315215",16,6270,"ENSG00000020181","ADGRA2","GO:0001525(angiogenesis);GO:0002040(sprouting angiogenesis);GO:0004888(transmembrane signaling receptor activity);GO:0004930(G protein-coupled receptor activity);GO:0005515(protein binding);GO:0005886(plasma membrane);GO:0007165(signal transduction);GO:0007166(cell surface receptor signaling pathway);GO:0007186(G protein-coupled receptor signaling pathway);GO:0007417(central nervous system development);GO:0009986(cell surface);GO:0010595(positive regulation of endothelial cell migration);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016055(Wnt signaling pathway);GO:0030175(filopodium);GO:0042995(cell projection);GO:0043542(endothelial cell migration);GO:0045765(regulation of angiogenesis);GO:0050920(regulation of chemotaxis);GO:0090210(regulation of establishment of blood-brain barrier);GO:0090263(positive regulation of canonical Wnt signaling pathway);GO:1900747(negative regulation of vascular endothelial growth factor signaling pathway);GO:1990909(Wnt signalosome)","NA","K08461","NA","adhesion G protein-coupled receptor A2 [Source:HGNC Symbol;Acc:HGNC:17849]",{"v":14.24341,"d":"14.24"},{"v":16.667168,"d":"16.67"},{"v":15.813737,"d":"15.81"},{"v":17.306374,"d":"17.31"},{"v":16.797028,"d":"16.80"},{"v":16.693245,"d":"16.69"},{"v":0.919830692762064,"d":"0.92"},{"v":-0.120559756751117,"d":"-0.12"},{"v":0.813257842904554,"d":"0.81"},1,"down","no"]
[43421,0,"chr12","-",53298655,53300314,"ENST00000550263",2,647,"ENSG00000257605","AC073611","NA","NA","NA","NA","novel transcript, antisense to PFDN5 and C12orf10",{"v":1.589601,"d":"1.59"},{"v":1.528353,"d":"1.53"},{"v":2.060643,"d":"2.06"},{"v":1.959676,"d":"1.96"},{"v":1.946787,"d":"1.95"},{"v":2.072321,"d":"2.07"},{"v":0.866162249714992,"d":"0.87"},{"v":-0.207290798648792,"d":"-0.21"},{"v":0.814922620026423,"d":"0.81"},1,"down","no"]
[18592,0,"chr10","-",812506,825244,"ENST00000448368",6,1438,"ENSG00000107929","LARP4B","GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0005515(protein binding);GO:0005730(nucleolus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0006417(regulation of translation);GO:0010494(cytoplasmic stress granule);GO:0016020(membrane);GO:0042788(polysomal ribosome);GO:0045727(positive regulation of translation)","NA","K18763","NA","La ribonucleoprotein domain family member 4B [Source:HGNC Symbol;Acc:HGNC:28987]",{"v":0.910521,"d":"0.91"},{"v":0.47616,"d":"0.48"},{"v":0.315419,"d":"0.32"},{"v":0.327667,"d":"0.33"},{"v":0.617061,"d":"0.62"},{"v":0.438817,"d":"0.44"},{"v":1.23024549255716,"d":"1.23"},{"v":0.298946230650259,"d":"0.30"},{"v":0.816778063803932,"d":"0.82"},1,"up","no"]
[198844,0,"chr9","+",122264887,122285287,"ENST00000441707",5,858,"ENSG00000148187","MRRF","GO:0005739(mitochondrion);GO:0005759(mitochondrial matrix);GO:0006412(translation);GO:0032790(ribosome disassembly);GO:0043023(ribosomal large subunit binding);GO:0070126(mitochondrial translational termination)","NA","K02838","NA","mitochondrial ribosome recycling factor [Source:HGNC Symbol;Acc:HGNC:7234]",{"v":0.289204,"d":"0.29"},{"v":0.548216,"d":"0.55"},{"v":0.976042,"d":"0.98"},{"v":0.549642,"d":"0.55"},{"v":0.617315,"d":"0.62"},{"v":0.990139,"d":"0.99"},{"v":0.840696009820611,"d":"0.84"},{"v":-0.250343869205836,"d":"-0.25"},{"v":0.818785579576674,"d":"0.82"},1,"down","no"]
[56259,0,"chr14","+",45095221,45115634,"ENST00000554439",15,2982,"ENSG00000185246","PRPF39","GO:0000243(commitment complex);GO:0000395(mRNA 5'-splice site recognition);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005685(U1 snRNP);GO:0006396(RNA processing);GO:0006397(mRNA processing);GO:0008380(RNA splicing);GO:0030627(pre-mRNA 5'-splice site binding);GO:0071004(U2-type prespliceosome)","NA","K13217","NA","pre-mRNA processing factor 39 [Source:HGNC Symbol;Acc:HGNC:20314]",{"v":0.388062,"d":"0.39"},{"v":0.535191,"d":"0.54"},{"v":0.440558,"d":"0.44"},{"v":0.396273,"d":"0.40"},{"v":0.341039,"d":"0.34"},{"v":0.410109,"d":"0.41"},{"v":1.18858814680924,"d":"1.19"},{"v":0.249248898862134,"d":"0.25"},{"v":0.820692032996771,"d":"0.82"},1,"up","no"]
[70260,0,"chr16","+",2520393,2529060,"ENST00000563633",9,1117,"ENSG00000162066","AMDHD2","GO:0005515(protein binding);GO:0005634(nucleus);GO:0005829(cytosol);GO:0005975(carbohydrate metabolic process);GO:0006044(N-acetylglucosamine metabolic process);GO:0006046(N-acetylglucosamine catabolic process);GO:0006048(UDP-N-acetylglucosamine biosynthetic process);GO:0008448(N-acetylglucosamine-6-phosphate deacetylase activity);GO:0016787(hydrolase activity);GO:0016810(hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds);GO:0019262(N-acetylneuraminate catabolic process);GO:0046872(metal ion binding);GO:0047419(N-acetylgalactosamine-6-phosphate deacetylase activity)","00520(Amino sugar and nucleotide sugar metabolism)","K01443","EC:3.5.1.25","amidohydrolase domain containing 2 [Source:HGNC Symbol;Acc:HGNC:24262]",{"v":0.849194,"d":"0.85"},{"v":0.500823,"d":"0.50"},{"v":0.860663,"d":"0.86"},{"v":0.657652,"d":"0.66"},{"v":0.517049,"d":"0.52"},{"v":0.652769,"d":"0.65"},{"v":1.20969427678703,"d":"1.21"},{"v":0.274642484612889,"d":"0.27"},{"v":0.824500799198863,"d":"0.82"},1,"up","no"]
[56777,0,"chr14","-",54474485,54488980,"ENST00000358056",7,4085,"ENSG00000197045","GMFB","GO:0003779(actin binding);GO:0004860(protein kinase inhibitor activity);GO:0005622(intracellular);GO:0006468(protein phosphorylation);GO:0006469(negative regulation of protein kinase activity);GO:0007399(nervous system development);GO:0007612(learning);GO:0007626(locomotory behavior);GO:0008047(enzyme activator activity);GO:0008083(growth factor activity);GO:0010469(regulation of signaling receptor activity);GO:0030479(actin cortical patch);GO:0034316(negative regulation of Arp2/3 complex-mediated actin nucleation);GO:0043085(positive regulation of catalytic activity);GO:0071846(actin filament debranching);GO:0071933(Arp2/3 complex binding)","NA","NA","NA","glia maturation factor beta [Source:HGNC Symbol;Acc:HGNC:4373]",{"v":18.747677,"d":"18.75"},{"v":19.986849,"d":"19.99"},{"v":14.73562,"d":"14.74"},{"v":18.419376,"d":"18.42"},{"v":19.674505,"d":"19.67"},{"v":19.799459,"d":"19.80"},{"v":0.923597532980478,"d":"0.92"},{"v":-0.114663775350025,"d":"-0.11"},{"v":0.826284361822815,"d":"0.83"},1,"down","no"]
[64903,0,"chr15","-",59663379,59678016,"ENST00000439052",7,1305,"ENSG00000140299","BNIP2","GO:0001824(blastocyst development);GO:0004309(exopolyphosphatase activity);GO:0005096(GTPase activator activity);GO:0005509(calcium ion binding);GO:0005515(protein binding);GO:0005635(nuclear envelope);GO:0005737(cytoplasm);GO:0005814(centriole);GO:0005829(cytosol);GO:0006798(polyphosphate catabolic process);GO:0006915(apoptotic process);GO:0007098(centrosome cycle);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0031616(spindle pole centrosome);GO:0043066(negative regulation of apoptotic process);GO:0043231(intracellular membrane-bounded organelle);GO:0043410(positive regulation of MAPK cascade);GO:0043547(positive regulation of GTPase activity);GO:0045666(positive regulation of neuron differentiation);GO:0048471(perinuclear region of cytoplasm);GO:0051057(positive regulation of small GTPase mediated signal transduction);GO:0051146(striated muscle cell differentiation);GO:0051149(positive regulation of muscle cell differentiation)","NA","NA","NA","BCL2 interacting protein 2 [Source:HGNC Symbol;Acc:HGNC:1083]",{"v":7.103957,"d":"7.10"},{"v":7.59747,"d":"7.60"},{"v":6.503509,"d":"6.50"},{"v":7.712402,"d":"7.71"},{"v":8.454546,"d":"8.45"},{"v":7.500703,"d":"7.50"},{"v":0.895945947487564,"d":"0.90"},{"v":-0.158516397921337,"d":"-0.16"},{"v":0.828300622103887,"d":"0.83"},1,"down","no"]
[73497,0,"chr16","-",29858358,29863205,"ENST00000563893",5,2253,"ENSG00000103502","CDIPT","GO:0000139(Golgi membrane);GO:0003881(CDP-diacylglycerol-inositol 3-phosphatidyltransferase activity);GO:0005515(protein binding);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005794(Golgi apparatus);GO:0005886(plasma membrane);GO:0006629(lipid metabolic process);GO:0006661(phosphatidylinositol biosynthetic process);GO:0008654(phospholipid biosynthetic process);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016740(transferase activity);GO:0016780(phosphotransferase activity, for other substituted phosphate groups);GO:0019992(diacylglycerol binding);GO:0030145(manganese ion binding);GO:0030246(carbohydrate binding);GO:0043178(alcohol binding);GO:0046341(CDP-diacylglycerol metabolic process)","00562(Inositol phosphate metabolism);00564(Glycerophospholipid metabolism);04070(Phosphatidylinositol signaling system)","K00999","EC:2.7.8.11","CDP-diacylglycerol--inositol 3-phosphatidyltransferase [Source:HGNC Symbol;Acc:HGNC:1769]",{"v":0.429272,"d":"0.43"},{"v":0.515346,"d":"0.52"},{"v":0.638854,"d":"0.64"},{"v":0.618661,"d":"0.62"},{"v":0.3905,"d":"0.39"},{"v":0.797906,"d":"0.80"},{"v":0.876266347622971,"d":"0.88"},{"v":-0.190558640597662,"d":"-0.19"},{"v":0.83013918596848,"d":"0.83"},1,"down","no"]
[16669,0,"chr1","+",220748322,220784815,"ENST00000366913",8,2146,"ENSG00000117791","MARC2","GO:0003824(catalytic activity);GO:0005739(mitochondrion);GO:0005741(mitochondrial outer membrane);GO:0005777(peroxisome);GO:0006805(xenobiotic metabolic process);GO:0008940(nitrate reductase activity);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016491(oxidoreductase activity);GO:0030151(molybdenum ion binding);GO:0030170(pyridoxal phosphate binding);GO:0042126(nitrate metabolic process);GO:0043546(molybdopterin cofactor binding);GO:0051410(detoxification of nitrogen compound);GO:0055114(oxidation-reduction process)","NA","NA","NA","mitochondrial amidoxime reducing component 2 [Source:HGNC Symbol;Acc:HGNC:26064]",{"v":4.992963,"d":"4.99"},{"v":5.322385,"d":"5.32"},{"v":4.296344,"d":"4.30"},{"v":4.37646,"d":"4.38"},{"v":4.021196,"d":"4.02"},{"v":4.282811,"d":"4.28"},{"v":1.15229920159881,"d":"1.15"},{"v":0.204515370093432,"d":"0.20"},{"v":0.832082504391653,"d":"0.83"},1,"up","no"]
[198497,0,"chr9","+",113565057,113582222,"ENST00000463806",3,671,"ENSG00000138835","RGS3","GO:0000188(inactivation of MAPK activity);GO:0003924(GTPase activity);GO:0005096(GTPase activator activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0007186(G protein-coupled receptor signaling pathway);GO:0008277(regulation of G protein-coupled receptor signaling pathway);GO:0009968(negative regulation of signal transduction);GO:0016020(membrane);GO:0043547(positive regulation of GTPase activity)","04360(Axon guidance)","K07524","NA","regulator of G protein signaling 3 [Source:HGNC Symbol;Acc:HGNC:9999]",{"v":2.644537,"d":"2.64"},{"v":3.380897,"d":"3.38"},{"v":2.426033,"d":"2.43"},{"v":4.243891,"d":"4.24"},{"v":2.811127,"d":"2.81"},{"v":2.519704,"d":"2.52"},{"v":0.88268536673963,"d":"0.88"},{"v":-0.180028814131067,"d":"-0.18"},{"v":0.833839362083547,"d":"0.83"},1,"down","no"]
[465,0,"chr1","+",1478026,1497848,"ENST00000472194",14,4314,"ENSG00000160072","ATAD3B","GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0005739(mitochondrion);GO:0005743(mitochondrial inner membrane);GO:0005886(plasma membrane);GO:0007005(mitochondrion organization);GO:0008270(zinc ion binding);GO:0016020(membrane);GO:0030667(secretory granule membrane);GO:0043312(neutrophil degranulation);GO:0101003(ficolin-1-rich granule membrane)","NA","K17681","NA","ATPase family, AAA domain containing 3B [Source:HGNC Symbol;Acc:HGNC:24007]",{"v":0.898957,"d":"0.90"},{"v":1.257213,"d":"1.26"},{"v":0.752007,"d":"0.75"},{"v":0.313743,"d":"0.31"},{"v":0.846703,"d":"0.85"},{"v":1.328173,"d":"1.33"},{"v":1.16859069226748,"d":"1.17"},{"v":0.224769703489353,"d":"0.22"},{"v":0.837476113259345,"d":"0.84"},1,"up","no"]
[197355,0,"chr9","-",92297484,92300026,"ENST00000463593",3,1238,"ENSG00000198000","NOL8","GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005730(nucleolus);GO:0006364(rRNA processing);GO:1902570(protein localization to nucleolus);GO:1990904(ribonucleoprotein complex)","NA","NA","NA","nucleolar protein 8 [Source:HGNC Symbol;Acc:HGNC:23387]",{"v":0.981377,"d":"0.98"},{"v":0.927943,"d":"0.93"},{"v":0.821591,"d":"0.82"},{"v":0.753608,"d":"0.75"},{"v":1.115292,"d":"1.12"},{"v":0.437339,"d":"0.44"},{"v":1.18414049888151,"d":"1.18"},{"v":0.243840267634158,"d":"0.24"},{"v":0.83906775327609,"d":"0.84"},1,"up","no"]
[115309,0,"chr2","-",96859718,96870080,"ENST00000305476",15,3652,"ENSG00000168758","SEMA4C","GO:0001755(neural crest cell migration);GO:0001843(neural tube closure);GO:0005515(protein binding);GO:0005615(extracellular space);GO:0005886(plasma membrane);GO:0005887(integral component of plasma membrane);GO:0007275(multicellular organism development);GO:0007399(nervous system development);GO:0014069(postsynaptic density);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0021535(cell migration in hindbrain);GO:0021549(cerebellum development);GO:0030054(cell junction);GO:0030154(cell differentiation);GO:0030215(semaphorin receptor binding);GO:0030335(positive regulation of cell migration);GO:0030672(synaptic vesicle membrane);GO:0031410(cytoplasmic vesicle);GO:0032874(positive regulation of stress-activated MAPK cascade);GO:0038191(neuropilin binding);GO:0042692(muscle cell differentiation);GO:0045202(synapse);GO:0045211(postsynaptic membrane);GO:0045499(chemorepellent activity);GO:0048843(negative regulation of axon extension involved in axon guidance);GO:0050919(negative chemotaxis);GO:0071526(semaphorin-plexin signaling pathway)","04360(Axon guidance)","K06521","NA","semaphorin 4C [Source:HGNC Symbol;Acc:HGNC:10731]",{"v":4.014019,"d":"4.01"},{"v":5.355817,"d":"5.36"},{"v":3.893389,"d":"3.89"},{"v":5.37542,"d":"5.38"},{"v":4.85358,"d":"4.85"},{"v":4.235281,"d":"4.24"},{"v":0.916964002566045,"d":"0.92"},{"v":-0.125062996114815,"d":"-0.13"},{"v":0.840725880683652,"d":"0.84"},1,"down","no"]
[187554,0,"chr8","-",23434093,23457639,"ENST00000523958",12,2026,"ENSG00000197217","ENTPD4","GO:0000139(Golgi membrane);GO:0000421(autophagosome membrane);GO:0005794(Golgi apparatus);GO:0006256(UDP catabolic process);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016787(hydrolase activity);GO:0017110(nucleoside-diphosphatase activity);GO:0030173(integral component of Golgi membrane);GO:0031410(cytoplasmic vesicle);GO:0034656(nucleobase-containing small molecule catabolic process);GO:0045134(uridine-diphosphatase activity);GO:0097637(integral component of autophagosome membrane)","00230(Purine metabolism);00240(Pyrimidine metabolism);04142(Lysosome)","K12305","EC:3.6.1.6","ectonucleoside triphosphate diphosphohydrolase 4 [Source:HGNC Symbol;Acc:HGNC:14573]",{"v":1.212086,"d":"1.21"},{"v":0.776068,"d":"0.78"},{"v":1.235221,"d":"1.24"},{"v":2.845071,"d":"2.85"},{"v":0.373644,"d":"0.37"},{"v":0.452516,"d":"0.45"},{"v":0.878009310773416,"d":"0.88"},{"v":-0.187691856111454,"d":"-0.19"},{"v":0.842502228544964,"d":"0.84"},1,"down","no"]
[68448,0,"chr15","+",92711808,92712110,"ENST00000431116",1,303,"ENSG00000253954","HMGN1P38","NA","NA","NA","NA","high mobility group nucleosome binding domain 1 pseudogene 38 [Source:HGNC Symbol;Acc:HGNC:39422]",{"v":5.217251,"d":"5.22"},{"v":8.01016,"d":"8.01"},{"v":6.14195,"d":"6.14"},{"v":7.923393,"d":"7.92"},{"v":7.419701,"d":"7.42"},{"v":6.460362,"d":"6.46"},{"v":0.888361964268417,"d":"0.89"},{"v":-0.170780470503195,"d":"-0.17"},{"v":0.844191390365001,"d":"0.84"},1,"down","no"]
[197824,0,"chr9","-",97904489,97922570,"ENST00000375119",5,1647,"ENSG00000136932","TRMO","GO:0008033(tRNA processing);GO:0008168(methyltransferase activity);GO:0016430(tRNA (adenine-N6-)-methyltransferase activity);GO:0016740(transferase activity);GO:0030488(tRNA methylation);GO:0032259(methylation)","NA","K22900","EC:2.1.1.-","tRNA methyltransferase O [Source:HGNC Symbol;Acc:HGNC:30967]",{"v":1.056001,"d":"1.06"},{"v":1.815312,"d":"1.82"},{"v":1.98482,"d":"1.98"},{"v":0.891317,"d":"0.89"},{"v":1.848094,"d":"1.85"},{"v":1.425191,"d":"1.43"},{"v":1.16604972095773,"d":"1.17"},{"v":0.221629307105968,"d":"0.22"},{"v":0.847933252506359,"d":"0.85"},1,"up","no"]
[119315,0,"chr2","+",173075846,173268015,"ENST00000375213",20,3859,"ENSG00000091436","MAP3K20","GO:0000077(DNA damage checkpoint);GO:0000165(MAPK cascade);GO:0000166(nucleotide binding);GO:0000186(activation of MAPKK activity);GO:0000287(magnesium ion binding);GO:0003723(RNA binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0004709(MAP kinase kinase kinase activity);GO:0005515(protein binding);GO:0005524(ATP binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0006468(protein phosphorylation);GO:0007010(cytoskeleton organization);GO:0007049(cell cycle);GO:0007050(cell cycle arrest);GO:0007093(mitotic cell cycle checkpoint);GO:0007257(activation of JUN kinase activity);GO:0008219(cell death);GO:0008283(cell population proliferation);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0016740(transferase activity);GO:0030154(cell differentiation);GO:0035556(intracellular signal transduction);GO:0042733(embryonic digit morphogenesis);GO:0043065(positive regulation of apoptotic process);GO:0046872(metal ion binding);GO:0051403(stress-activated MAPK cascade);GO:0060173(limb development);GO:0071480(cellular response to gamma radiation)","04010(MAPK signaling pathway)","K04424","EC:2.7.11.25","mitogen-activated protein kinase kinase kinase 20 [Source:HGNC Symbol;Acc:HGNC:17797]",{"v":8.28919,"d":"8.29"},{"v":8.963154,"d":"8.96"},{"v":7.436899,"d":"7.44"},{"v":10.420812,"d":"10.42"},{"v":9.947404,"d":"9.95"},{"v":6.15653,"d":"6.16"},{"v":0.930800355260706,"d":"0.93"},{"v":-0.103456333507271,"d":"-0.10"},{"v":0.849524391753576,"d":"0.85"},1,"down","no"]
[16308,0,"chr1","+",212285410,212361853,"ENST00000261461",13,3245,"ENSG00000066027","PPP2R5A","GO:0000159(protein phosphatase type 2A complex);GO:0000775(chromosome, centromeric region);GO:0004721(phosphoprotein phosphatase activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005694(chromosome);GO:0005737(cytoplasm);GO:0005813(centrosome);GO:0005829(cytosol);GO:0006470(protein dephosphorylation);GO:0007165(signal transduction);GO:0016020(membrane);GO:0019888(protein phosphatase regulator activity);GO:0019900(kinase binding);GO:0030018(Z disc);GO:0031430(M band);GO:0031952(regulation of protein autophosphorylation);GO:0035307(positive regulation of protein dephosphorylation);GO:0043666(regulation of phosphoprotein phosphatase activity);GO:0072542(protein phosphatase activator activity);GO:0090219(negative regulation of lipid kinase activity);GO:1903077(negative regulation of protein localization to plasma membrane)","03015(mRNA surveillance pathway);04071(Sphingolipid signaling pathway);04114(Oocyte meiosis);04151(PI3K-Akt signaling pathway);04152(AMPK signaling pathway);04261(Adrenergic signaling in cardiomyocytes);04728(Dopaminergic synapse);05165(Human papillomavirus infection)","NA","NA","protein phosphatase 2 regulatory subunit B'alpha [Source:HGNC Symbol;Acc:HGNC:9309]",{"v":15.144031,"d":"15.14"},{"v":16.720398,"d":"16.72"},{"v":15.943514,"d":"15.94"},{"v":17.22349,"d":"17.22"},{"v":17.818367,"d":"17.82"},{"v":16.016975,"d":"16.02"},{"v":0.936330525539636,"d":"0.94"},{"v":-0.0949102024897919,"d":"-0.09"},{"v":0.85093868622556,"d":"0.85"},1,"down","no"]
[97797,0,"chr19","-",6210381,6279975,"ENST00000252674",12,4532,"ENSG00000130382","MLLT1","GO:0000981(DNA-binding transcription factor activity, RNA polymerase II-specific);GO:0001650(fibrillar center);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0006355(regulation of transcription, DNA-templated);GO:0006357(regulation of transcription by RNA polymerase II);GO:0006366(transcription by RNA polymerase II);GO:0006368(transcription elongation from RNA polymerase II promoter);GO:0006469(negative regulation of protein kinase activity);GO:0008023(transcription elongation factor complex)","05202(Transcriptional misregulation in cancer)","K15187","NA","MLLT1, super elongation complex subunit [Source:HGNC Symbol;Acc:HGNC:7134]",{"v":20.227034,"d":"20.23"},{"v":19.886038,"d":"19.89"},{"v":17.250153,"d":"17.25"},{"v":18.156006,"d":"18.16"},{"v":15.341191,"d":"15.34"},{"v":18.508261,"d":"18.51"},{"v":1.10302316729909,"d":"1.10"},{"v":0.141463092830028,"d":"0.14"},{"v":0.852613223770357,"d":"0.85"},1,"up","no"]
[17446,0,"chr1","+",230979094,231000733,"ENST00000310256",6,1428,"ENSG00000173409","ARV1","GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005794(Golgi apparatus);GO:0006629(lipid metabolic process);GO:0006665(sphingolipid metabolic process);GO:0006695(cholesterol biosynthetic process);GO:0006869(lipid transport);GO:0008202(steroid metabolic process);GO:0008203(cholesterol metabolic process);GO:0008206(bile acid metabolic process);GO:0015248(sterol transporter activity);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016125(sterol metabolic process);GO:0030301(cholesterol transport);GO:0032366(intracellular sterol transport);GO:0032383(regulation of intracellular cholesterol transport);GO:0032541(cortical endoplasmic reticulum);GO:0090181(regulation of cholesterol metabolic process);GO:0097036(regulation of plasma membrane sterol distribution)","NA","K21848","NA","ARV1 homolog, fatty acid homeostasis modulator [Source:HGNC Symbol;Acc:HGNC:29561]",{"v":4.401286,"d":"4.40"},{"v":5.983119,"d":"5.98"},{"v":4.943779,"d":"4.94"},{"v":4.495514,"d":"4.50"},{"v":7.700719,"d":"7.70"},{"v":1.03061,"d":"1.03"},{"v":1.15886942938689,"d":"1.16"},{"v":0.212718026061633,"d":"0.21"},{"v":0.854235681863737,"d":"0.85"},1,"up","no"]
[31044,0,"chr11","+",61362374,61369509,"ENST00000278826",5,1475,"ENSG00000149483","TMEM138","GO:0005773(vacuole);GO:0005774(vacuolar membrane);GO:0005929(cilium);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0030030(cell projection organization);GO:0042995(cell projection);GO:0060271(cilium assembly)","NA","K22867","NA","transmembrane protein 138 [Source:HGNC Symbol;Acc:HGNC:26944]",{"v":2.518924,"d":"2.52"},{"v":3.757819,"d":"3.76"},{"v":3.802049,"d":"3.80"},{"v":4.484222,"d":"4.48"},{"v":3.135777,"d":"3.14"},{"v":3.467448,"d":"3.47"},{"v":0.909027299070742,"d":"0.91"},{"v":-0.137604474128487,"d":"-0.14"},{"v":0.857736808986745,"d":"0.86"},1,"down","no"]
[169106,0,"chr6","+",31666094,31669464,"ENST00000481269",5,785,"ENSG00000204435","CSNK2B","GO:0000785(chromatin);GO:0003682(chromatin binding);GO:0004674(protein serine/threonine kinase activity);GO:0005102(signaling receptor binding);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0005929(cilium);GO:0005956(protein kinase CK2 complex);GO:0006457(protein folding);GO:0006656(phosphatidylcholine biosynthetic process);GO:0007165(signal transduction);GO:0008134(transcription factor binding);GO:0008285(negative regulation of cell population proliferation);GO:0010862(positive regulation of pathway-restricted SMAD protein phosphorylation);GO:0016055(Wnt signaling pathway);GO:0016236(macroautophagy);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0016363(nuclear matrix);GO:0018107(peptidyl-threonine phosphorylation);GO:0019887(protein kinase regulator activity);GO:0019904(protein domain specific binding);GO:0031519(PcG protein complex);GO:0032927(positive regulation of activin receptor signaling pathway);GO:0033211(adiponectin-activated signaling pathway);GO:0033574(response to testosterone);GO:0034622(cellular protein-containing complex assembly);GO:0034774(secretory granule lumen);GO:0042802(identical protein binding);GO:0042995(cell projection);GO:0043021(ribonucleoprotein complex binding);GO:0043312(neutrophil degranulation);GO:0043537(negative regulation of blood vessel endothelial cell migration);GO:0045859(regulation of protein kinase activity);GO:0046872(metal ion binding);GO:0051101(regulation of DNA binding);GO:0061154(endothelial tube morphogenesis);GO:0070062(extracellular exosome);GO:0097421(liver regeneration);GO:1901796(regulation of signal transduction by p53 class mediator);GO:1904813(ficolin-1-rich granule lumen)","03008(Ribosome biogenesis in eukaryotes);04064(NF-kappa B signaling pathway);04137(Mitophagy - animal);04310(Wnt signaling pathway);04520(Adherens junction);05162(Measles)","NA","NA","casein kinase 2 beta [Source:HGNC Symbol;Acc:HGNC:2460]",{"v":9.442065,"d":"9.44"},{"v":6.997248,"d":"7.00"},{"v":3.151102,"d":"3.15"},{"v":11.243059,"d":"11.24"},{"v":8.046598,"d":"8.05"},{"v":2.483124,"d":"2.48"},{"v":0.899766318321945,"d":"0.90"},{"v":-0.152377732526289,"d":"-0.15"},{"v":0.859407372692093,"d":"0.86"},1,"down","no"]
[197438,0,"chr9","+",93058701,93085133,"ENST00000375472",5,1196,"ENSG00000157303","SUSD3","GO:0005886(plasma membrane);GO:0016020(membrane);GO:0016021(integral component of membrane)","NA","NA","NA","sushi domain containing 3 [Source:HGNC Symbol;Acc:HGNC:28391]",{"v":0.875489,"d":"0.88"},{"v":0.650455,"d":"0.65"},{"v":0.696146,"d":"0.70"},{"v":0.603533,"d":"0.60"},{"v":0.715535,"d":"0.72"},{"v":0.578786,"d":"0.58"},{"v":1.17084348954135,"d":"1.17"},{"v":0.227548238987397,"d":"0.23"},{"v":0.860935265099669,"d":"0.86"},1,"up","no"]
[4366,0,"chr1","+",36323734,36329221,"ENST00000373137",2,1838,"ENSG00000116883","AL591845","NA","NA","NA","NA","novel transcript, antisense to EVA1B",{"v":1.085353,"d":"1.09"},{"v":1.141056,"d":"1.14"},{"v":1.381261,"d":"1.38"},{"v":1.370936,"d":"1.37"},{"v":1.205966,"d":"1.21"},{"v":1.412399,"d":"1.41"},{"v":0.904336373715596,"d":"0.90"},{"v":-0.145068602747113,"d":"-0.15"},{"v":0.862614144654701,"d":"0.86"},1,"down","no"]
[83655,0,"chr17","-",29560547,29567037,"ENST00000307201",2,3492,"ENSG00000168792","ABHD15","GO:0005576(extracellular region);GO:0016020(membrane);GO:0016787(hydrolase activity);GO:0044255(cellular lipid metabolic process)","NA","K13707","NA","abhydrolase domain containing 15 [Source:HGNC Symbol;Acc:HGNC:26971]",{"v":4.449646,"d":"4.45"},{"v":4.920001,"d":"4.92"},{"v":4.569645,"d":"4.57"},{"v":5.116446,"d":"5.12"},{"v":5.112779,"d":"5.11"},{"v":4.736629,"d":"4.74"},{"v":0.931406386832318,"d":"0.93"},{"v":-0.102517319858474,"d":"-0.10"},{"v":0.864273304568428,"d":"0.86"},1,"down","no"]
[1692,0,"chr1","+",12019498,12032045,"ENST00000235332",10,1541,"ENSG00000116691","MIIP","GO:0005515(protein binding);GO:0010972(negative regulation of G2/M transition of mitotic cell cycle);GO:0030336(negative regulation of cell migration)","NA","NA","NA","migration and invasion inhibitory protein [Source:HGNC Symbol;Acc:HGNC:25715]",{"v":5.416666,"d":"5.42"},{"v":4.343975,"d":"4.34"},{"v":5.813244,"d":"5.81"},{"v":4.991521,"d":"4.99"},{"v":4.643353,"d":"4.64"},{"v":4.16047,"d":"4.16"},{"v":1.12892328020236,"d":"1.13"},{"v":0.174947446223907,"d":"0.17"},{"v":0.86752883864177,"d":"0.87"},1,"up","no"]
[88946,0,"chr17","+",63787036,63798196,"ENST00000580108",3,545,"ENSG00000198231","DDX42","GO:0000166(nucleotide binding);GO:0000398(mRNA splicing, via spliceosome);GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0004386(helicase activity);GO:0005515(protein binding);GO:0005524(ATP binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0008104(protein localization);GO:0015030(Cajal body);GO:0016020(membrane);GO:0016607(nuclear speck);GO:0016787(hydrolase activity);GO:0042981(regulation of apoptotic process)","03040(Spliceosome)","NA","NA","DEAD-box helicase 42 [Source:HGNC Symbol;Acc:HGNC:18676]",{"v":4.894405,"d":"4.89"},{"v":5.023901,"d":"5.02"},{"v":6.493045,"d":"6.49"},{"v":5.838634,"d":"5.84"},{"v":0.748775,"d":"0.75"},{"v":7.60555,"d":"7.61"},{"v":1.15630229045261,"d":"1.16"},{"v":0.20951860884701,"d":"0.21"},{"v":0.869109324297438,"d":"0.87"},1,"up","no"]
[181891,0,"chr7","+",100101866,100109039,"ENST00000416938",13,3408,"ENSG00000221838","AP4M1","GO:0005515(protein binding);GO:0005768(endosome);GO:0005769(early endosome);GO:0005794(Golgi apparatus);GO:0005802(trans-Golgi network);GO:0005829(cytosol);GO:0006605(protein targeting);GO:0006622(protein targeting to lysosome);GO:0006886(intracellular protein transport);GO:0006895(Golgi to endosome transport);GO:0008104(protein localization);GO:0015031(protein transport);GO:0016020(membrane);GO:0016192(vesicle-mediated transport);GO:0019904(protein domain specific binding);GO:0030124(AP-4 adaptor complex);GO:0030131(clathrin adaptor complex);GO:0031904(endosome lumen);GO:0032588(trans-Golgi network membrane);GO:0070062(extracellular exosome);GO:0090160(Golgi to lysosome transport);GO:1903361(protein localization to basolateral plasma membrane)","04142(Lysosome)","K12402","NA","adaptor related protein complex 4 subunit mu 1 [Source:HGNC Symbol;Acc:HGNC:574]",{"v":2.140671,"d":"2.14"},{"v":2.080498,"d":"2.08"},{"v":2.20908,"d":"2.21"},{"v":2.926287,"d":"2.93"},{"v":2.147845,"d":"2.15"},{"v":1.900625,"d":"1.90"},{"v":0.921931617115836,"d":"0.92"},{"v":-0.117268349988271,"d":"-0.12"},{"v":0.870786311137478,"d":"0.87"},1,"down","no"]
[192362,0,"chr8","+",124474738,124487914,"ENST00000303545",2,2637,"ENSG00000170881","RNF139","GO:0002020(protease binding);GO:0004842(ubiquitin-protein transferase activity);GO:0005515(protein binding);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0008270(zinc ion binding);GO:0008285(negative regulation of cell population proliferation);GO:0012505(endomembrane system);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016567(protein ubiquitination);GO:0016740(transferase activity);GO:0017148(negative regulation of translation);GO:0019787(ubiquitin-like protein transferase activity);GO:0031648(protein destabilization);GO:0036503(ERAD pathway);GO:0036513(Derlin-1 retrotranslocation complex);GO:0038023(signaling receptor activity);GO:0044322(endoplasmic reticulum quality control compartment);GO:0046872(metal ion binding);GO:0060628(regulation of ER to Golgi vesicle-mediated transport);GO:0061630(ubiquitin protein ligase activity);GO:0070613(regulation of protein processing);GO:1904380(endoplasmic reticulum mannose trimming);GO:2000060(positive regulation of ubiquitin-dependent protein catabolic process)","NA","K15703","EC:2.3.2.27","ring finger protein 139 [Source:HGNC Symbol;Acc:HGNC:17023]",{"v":23.271307,"d":"23.27"},{"v":22.73049,"d":"22.73"},{"v":22.277227,"d":"22.28"},{"v":20.958071,"d":"20.96"},{"v":21.244709,"d":"21.24"},{"v":20.295815,"d":"20.30"},{"v":1.09248894315144,"d":"1.09"},{"v":0.127618678589669,"d":"0.13"},{"v":0.872394064476484,"d":"0.87"},1,"up","no"]
[20006,0,"chr10","-",28522685,28532354,"ENST00000528337",3,2608,"ENSG00000254635","WAC-AS1","NA","NA","NA","NA","WAC antisense RNA 1 (head to head) [Source:HGNC Symbol;Acc:HGNC:27347]",{"v":1.180022,"d":"1.18"},{"v":0.848196,"d":"0.85"},{"v":1.400033,"d":"1.40"},{"v":1.616941,"d":"1.62"},{"v":1.245164,"d":"1.25"},{"v":0.882672,"d":"0.88"},{"v":0.915475340721223,"d":"0.92"},{"v":-0.127407068830162,"d":"-0.13"},{"v":0.874676034083454,"d":"0.87"},1,"down","no"]
[98981,0,"chr19","+",10996265,11040314,"ENST00000644267",21,3382,"ENSG00000127616","SMARCA4","GO:0000122(negative regulation of transcription by RNA polymerase II);GO:0000166(nucleotide binding);GO:0000790(nuclear chromatin);GO:0000978(RNA polymerase II proximal promoter sequence-specific DNA binding);GO:0000980(RNA polymerase II distal enhancer sequence-specific DNA binding);GO:0001164(RNA polymerase I CORE element sequence-specific DNA binding);GO:0001188(RNA polymerase I preinitiation complex assembly);GO:0002039(p53 binding);GO:0003407(neural retina development);GO:0003713(transcription coactivator activity);GO:0003714(transcription corepressor activity);GO:0003723(RNA binding);GO:0004386(helicase activity);GO:0005515(protein binding);GO:0005524(ATP binding);GO:0005615(extracellular space);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005730(nucleolus);GO:0006325(chromatin organization);GO:0006337(nucleosome disassembly);GO:0006338(chromatin remodeling);GO:0006355(regulation of transcription, DNA-templated);GO:0006357(regulation of transcription by RNA polymerase II);GO:0007399(nervous system development);GO:0008094(DNA-dependent ATPase activity);GO:0008134(transcription factor binding);GO:0016020(membrane);GO:0016514(SWI/SNF complex);GO:0016787(hydrolase activity);GO:0016817(hydrolase activity, acting on acid anhydrides);GO:0016887(ATPase activity);GO:0030177(positive regulation of Wnt signaling pathway);GO:0030308(negative regulation of cell growth);GO:0030957(Tat protein binding);GO:0031492(nucleosomal DNA binding);GO:0032991(protein-containing complex);GO:0038111(interleukin-7-mediated signaling pathway);GO:0042393(histone binding);GO:0043044(ATP-dependent chromatin remodeling);GO:0043923(positive regulation by host of viral transcription);GO:0045892(negative regulation of transcription, DNA-templated);GO:0045893(positive regulation of transcription, DNA-templated);GO:0045944(positive regulation of transcription by RNA polymerase II);GO:0047485(protein N-terminus binding);GO:0050681(androgen receptor binding);GO:0051091(positive regulation of DNA-binding transcription factor activity);GO:0060766(negative regulation of androgen receptor signaling pathway);GO:0070182(DNA polymerase binding);GO:0070577(lysine-acetylated histone binding);GO:0071564(npBAF complex);GO:0071565(nBAF complex);GO:1901838(positive regulation of transcription of nucleolar large rRNA by RNA polymerase I);GO:1902661(positive regulation of glucose mediated signaling pathway);GO:1902895(positive regulation of pri-miRNA transcription by RNA polymerase II);GO:1904837(beta-catenin-TCF complex assembly)","04714(Thermogenesis);05225(Hepatocellular carcinoma)","NA","NA","SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 [Source:HGNC Symbol;Acc:HGNC:11100]",{"v":0.041966,"d":"0.04"},{"v":0.001318,"d":"0.00"},{"v":2.153488,"d":"2.15"},0,{"v":2.769016,"d":"2.77"},0,{"v":0.793340305725933,"d":"0.79"},{"v":-0.333988247786227,"d":"-0.33"},{"v":0.877291278045364,"d":"0.88"},1,"down","no"]
[29059,0,"chr11","+",34916632,34995275,"ENST00000430469",6,952,"ENSG00000110435","PDHX","GO:0005515(protein binding);GO:0005739(mitochondrion);GO:0005759(mitochondrial matrix);GO:0006090(pyruvate metabolic process);GO:0016746(transferase activity, transferring acyl groups);GO:0034604(pyruvate dehydrogenase (NAD+) activity);GO:0045254(pyruvate dehydrogenase complex);GO:0061732(mitochondrial acetyl-CoA biosynthetic process from pyruvate)","00010(Glycolysis / Gluconeogenesis);00020(Citrate cycle (TCA cycle));00620(Pyruvate metabolism)","K13997","NA","pyruvate dehydrogenase complex component X [Source:HGNC Symbol;Acc:HGNC:21350]",0,{"v":1.021622,"d":"1.02"},{"v":0.39823,"d":"0.40"},0,{"v":0.175008,"d":"0.18"},{"v":0.952405,"d":"0.95"},{"v":1.25938941630086,"d":"1.26"},{"v":0.33272444834569,"d":"0.33"},{"v":0.878956634890652,"d":"0.88"},1,"up","no"]
[194709,0,"chr9","+",15553043,15974037,"ENST00000380701",26,6553,"ENSG00000164989","CCDC171","NA","NA","NA","NA","coiled-coil domain containing 171 [Source:HGNC Symbol;Acc:HGNC:29828]",{"v":0.510223,"d":"0.51"},{"v":0.530379,"d":"0.53"},{"v":0.542646,"d":"0.54"},{"v":0.489819,"d":"0.49"},{"v":0.402908,"d":"0.40"},{"v":0.511463,"d":"0.51"},{"v":1.12751693146939,"d":"1.13"},{"v":0.173149098015925,"d":"0.17"},{"v":0.880572685891115,"d":"0.88"},1,"up","no"]
[174986,0,"chr6","-",151364115,151391559,"ENST00000325144",3,3103,"ENSG00000181472","ZBTB2","GO:0000122(negative regulation of transcription by RNA polymerase II);GO:0000978(RNA polymerase II proximal promoter sequence-specific DNA binding);GO:0000981(DNA-binding transcription factor activity, RNA polymerase II-specific);GO:0001227(DNA-binding transcription repressor activity, RNA polymerase II-specific);GO:0003676(nucleic acid binding);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0005634(nucleus);GO:0046872(metal ion binding)","NA","K10489","NA","zinc finger and BTB domain containing 2 [Source:HGNC Symbol;Acc:HGNC:20868]",{"v":6.381684,"d":"6.38"},{"v":6.497368,"d":"6.50"},{"v":6.249896,"d":"6.25"},{"v":6.758393,"d":"6.76"},{"v":6.369546,"d":"6.37"},{"v":7.118956,"d":"7.12"},{"v":0.944784274329471,"d":"0.94"},{"v":-0.0819431432087035,"d":"-0.08"},{"v":0.882291005696995,"d":"0.88"},1,"down","no"]
[22811,0,"chr10","+",87357668,87367195,"ENST00000381697",7,3290,"ENSG00000214562","NUTM2D","NA","NA","NA","NA","NUT family member 2D [Source:HGNC Symbol;Acc:HGNC:23447]",{"v":0.751947,"d":"0.75"},{"v":0.776451,"d":"0.78"},{"v":0.957568,"d":"0.96"},{"v":0.599233,"d":"0.60"},{"v":0.792305,"d":"0.79"},{"v":1.319387,"d":"1.32"},{"v":0.917017623136015,"d":"0.92"},{"v":-0.12497863525828,"d":"-0.12"},{"v":0.883902103054408,"d":"0.88"},1,"down","no"]
[125765,0,"chr20","-",28580709,28602664,"ENST00000358464",9,769,"ENSG00000282826","FRG1CP","NA","NA","NA","NA","FSHD region gene 1 family member C, pseudogene [Source:HGNC Symbol;Acc:HGNC:51762]",{"v":5.740262,"d":"5.74"},{"v":5.156839,"d":"5.16"},{"v":5.835236,"d":"5.84"},{"v":5.672631,"d":"5.67"},{"v":4.319126,"d":"4.32"},{"v":4.962855,"d":"4.96"},{"v":1.11887469898918,"d":"1.12"},{"v":0.162048480220754,"d":"0.16"},{"v":0.887748289528037,"d":"0.89"},1,"up","no"]
[53138,0,"chr13","+",102394630,102395703,"ENST00000606448",1,1074,"ENSG00000272143","FGF14-AS2","NA","NA","NA","NA","FGF14 antisense RNA 2 [Source:HGNC Symbol;Acc:HGNC:44368]",{"v":0.625004,"d":"0.63"},{"v":0.806731,"d":"0.81"},{"v":0.846068,"d":"0.85"},{"v":0.841613,"d":"0.84"},{"v":0.549309,"d":"0.55"},{"v":0.614615,"d":"0.61"},{"v":1.13575715631275,"d":"1.14"},{"v":0.183654395726494,"d":"0.18"},{"v":0.88931359028154,"d":"0.89"},1,"up","no"]
[206843,0,"chrX","+",151397204,151409364,"ENST00000330374",3,4717,"ENSG00000160131","VMA21","GO:0005764(lysosome);GO:0005773(vacuole);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0012507(ER to Golgi transport vesicle membrane);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0031410(cytoplasmic vesicle);GO:0033116(endoplasmic reticulum-Golgi intermediate compartment membrane);GO:0043462(regulation of ATPase activity);GO:0070072(vacuolar proton-transporting V-type ATPase complex assembly)","NA","NA","NA","VMA21, vacuolar ATPase assembly factor [Source:HGNC Symbol;Acc:HGNC:22082]",{"v":5.901409,"d":"5.90"},{"v":5.843136,"d":"5.84"},{"v":5.75375,"d":"5.75"},{"v":5.948514,"d":"5.95"},{"v":6.101742,"d":"6.10"},{"v":6.311467,"d":"6.31"},{"v":0.952976744066992,"d":"0.95"},{"v":-0.0694870870780653,"d":"-0.07"},{"v":0.89077014882907,"d":"0.89"},1,"down","no"]
[137270,0,"chr3","-",15414374,15427532,"ENST00000383789",6,1413,"ENSG00000206562","METTL6","GO:0002946(tRNA C5-cytosine methylation);GO:0008168(methyltransferase activity);GO:0016428(tRNA (cytosine-5-)-methyltransferase activity);GO:0016740(transferase activity);GO:0032259(methylation)","NA","K00599","EC:2.1.1.-","methyltransferase like 6 [Source:HGNC Symbol;Acc:HGNC:28343]",{"v":0.888039,"d":"0.89"},{"v":0.611486,"d":"0.61"},{"v":0.42451,"d":"0.42"},{"v":0.910692,"d":"0.91"},{"v":0.598552,"d":"0.60"},{"v":0.586138,"d":"0.59"},{"v":0.918226366361838,"d":"0.92"},{"v":-0.123078236052793,"d":"-0.12"},{"v":0.892213005699189,"d":"0.89"},1,"down","no"]
[127518,0,"chr20","-",46499630,46509622,"ENST00000615481",4,3706,"ENSG00000198185","ZNF334","GO:0000981(DNA-binding transcription factor activity, RNA polymerase II-specific);GO:0003676(nucleic acid binding);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0005622(intracellular);GO:0005634(nucleus);GO:0006355(regulation of transcription, DNA-templated);GO:0006357(regulation of transcription by RNA polymerase II);GO:0046872(metal ion binding)","05168(Herpes simplex virus 1 infection)","K09228","NA","zinc finger protein 334 [Source:HGNC Symbol;Acc:HGNC:15806]",0,{"v":0.227114,"d":"0.23"},{"v":1.194634,"d":"1.19"},{"v":0.00248,"d":"0.00"},0,{"v":1.145221,"d":"1.15"},{"v":1.2387790896758,"d":"1.24"},{"v":0.308918935949204,"d":"0.31"},{"v":0.894068736747343,"d":"0.89"},1,"up","no"]
[130426,0,"chr21","-",39175590,39183385,"ENST00000431628",6,760,"ENSG00000183527","PSMG1","GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0005783(endoplasmic reticulum);GO:0005794(Golgi apparatus);GO:0005829(cytosol);GO:0021930(cerebellar granule cell precursor proliferation);GO:0043248(proteasome assembly);GO:0070628(proteasome binding);GO:0080129(proteasome core complex assembly)","NA","K11875","NA","proteasome assembly chaperone 1 [Source:HGNC Symbol;Acc:HGNC:3043]",{"v":1.259874,"d":"1.26"},{"v":1.045364,"d":"1.05"},{"v":1.732412,"d":"1.73"},{"v":1.141476,"d":"1.14"},{"v":1.076497,"d":"1.08"},{"v":1.335789,"d":"1.34"},{"v":1.13616218531235,"d":"1.14"},{"v":0.184168791924134,"d":"0.18"},{"v":0.895443654402442,"d":"0.90"},1,"up","no"]
[37867,0,"chr11","+",125626229,125627668,"ENST00000533778",3,561,"ENSG00000149554","CHEK1","GO:0000077(DNA damage checkpoint);GO:0000086(G2/M transition of mitotic cell cycle);GO:0000166(nucleotide binding);GO:0000781(chromosome, telomeric region);GO:0000785(chromatin);GO:0000794(condensed nuclear chromosome);GO:0001833(inner cell mass cell proliferation);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005515(protein binding);GO:0005524(ATP binding);GO:0005615(extracellular space);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005657(replication fork);GO:0005737(cytoplasm);GO:0005813(centrosome);GO:0005815(microtubule organizing center);GO:0005829(cytosol);GO:0005856(cytoskeleton);GO:0006260(DNA replication);GO:0006281(DNA repair);GO:0006468(protein phosphorylation);GO:0006915(apoptotic process);GO:0006974(cellular response to DNA damage stimulus);GO:0006975(DNA damage induced protein phosphorylation);GO:0006997(nucleus organization);GO:0007049(cell cycle);GO:0007093(mitotic cell cycle checkpoint);GO:0010468(regulation of gene expression);GO:0010569(regulation of double-strand break repair via homologous recombination);GO:0010767(regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0016740(transferase activity);GO:0018107(peptidyl-threonine phosphorylation);GO:0019904(protein domain specific binding);GO:0032991(protein-containing complex);GO:0035402(histone kinase activity (H3-T11 specific));GO:0035407(histone H3-T11 phosphorylation);GO:0035556(intracellular signal transduction);GO:0042127(regulation of cell population proliferation);GO:0043231(intracellular membrane-bounded organelle);GO:0045787(positive regulation of cell cycle);GO:0045839(negative regulation of mitotic nuclear division);GO:0046602(regulation of mitotic centrosome separation);GO:0048096(chromatin-mediated maintenance of transcription);GO:0070317(negative regulation of G0 to G1 transition);GO:0071260(cellular response to mechanical stimulus);GO:0072425(signal transduction involved in G2 DNA damage checkpoint);GO:0090399(replicative senescence);GO:1901796(regulation of signal transduction by p53 class mediator);GO:1902742(apoptotic process involved in development);GO:2000615(regulation of histone H3-K9 acetylation)","04110(Cell cycle);04115(p53 signaling pathway);04218(Cellular senescence);05166(Human T-cell leukemia virus 1 infection);05170(Human immunodeficiency virus 1 infection);05203(Viral carcinogenesis)","NA","NA","checkpoint kinase 1 [Source:HGNC Symbol;Acc:HGNC:1925]",{"v":1.864669,"d":"1.86"},{"v":1.654135,"d":"1.65"},{"v":1.716324,"d":"1.72"},{"v":2.15202,"d":"2.15"},{"v":1.685651,"d":"1.69"},{"v":1.811874,"d":"1.81"},{"v":0.926645951134118,"d":"0.93"},{"v":-0.109909869423597,"d":"-0.11"},{"v":0.899127984019192,"d":"0.90"},1,"down","no"]
[140025,0,"chr3","+",49674351,49683971,"ENST00000296456",22,2879,"ENSG00000164062","APEH","GO:0003723(RNA binding);GO:0004252(serine-type endopeptidase activity);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0006415(translational termination);GO:0006508(proteolysis);GO:0008236(serine-type peptidase activity);GO:0008242(omega peptidase activity);GO:0016787(hydrolase activity);GO:0031965(nuclear membrane);GO:0042802(identical protein binding);GO:0043312(neutrophil degranulation);GO:0050435(amyloid-beta metabolic process);GO:0070062(extracellular exosome);GO:1904813(ficolin-1-rich granule lumen)","NA","NA","NA","acylaminoacyl-peptide hydrolase [Source:HGNC Symbol;Acc:HGNC:586]",{"v":18.237619,"d":"18.24"},{"v":18.118444,"d":"18.12"},{"v":18.639349,"d":"18.64"},{"v":17.021654,"d":"17.02"},{"v":17.542711,"d":"17.54"},{"v":16.529781,"d":"16.53"},{"v":1.07635446142891,"d":"1.08"},{"v":0.10615325961712,"d":"0.11"},{"v":0.900734605529494,"d":"0.90"},1,"up","no"]
[60883,0,"chr14","+",103731431,103733663,"ENST00000554757",2,2013,"ENSG00000100711","ZFYVE21","GO:0005515(protein binding);GO:0005768(endosome);GO:0005925(focal adhesion);GO:0030054(cell junction);GO:0031410(cytoplasmic vesicle);GO:0046872(metal ion binding)","NA","NA","NA","zinc finger FYVE-type containing 21 [Source:HGNC Symbol;Acc:HGNC:20760]",{"v":0.216973,"d":"0.22"},{"v":0.222856,"d":"0.22"},{"v":0.557764,"d":"0.56"},{"v":0.177781,"d":"0.18"},{"v":0.493632,"d":"0.49"},{"v":0.418739,"d":"0.42"},{"v":0.915095326156353,"d":"0.92"},{"v":-0.128006057053889,"d":"-0.13"},{"v":0.902482027292679,"d":"0.90"},1,"down","no"]
[77420,0,"chr16","+",72093847,72112912,"ENST00000268482",27,4323,"ENSG00000140829","DHX38","GO:0000166(nucleotide binding);GO:0000398(mRNA splicing, via spliceosome);GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0004386(helicase activity);GO:0005515(protein binding);GO:0005524(ATP binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005681(spliceosomal complex);GO:0006397(mRNA processing);GO:0006405(RNA export from nucleus);GO:0006406(mRNA export from nucleus);GO:0008380(RNA splicing);GO:0016020(membrane);GO:0016787(hydrolase activity);GO:0031124(mRNA 3'-end processing);GO:0034459(ATP-dependent 3'-5' RNA helicase activity);GO:0071013(catalytic step 2 spliceosome)","03040(Spliceosome)","K12815","EC:3.6.4.13","DEAH-box helicase 38 [Source:HGNC Symbol;Acc:HGNC:17211]",{"v":11.42953,"d":"11.43"},{"v":11.338105,"d":"11.34"},{"v":12.47232,"d":"12.47"},{"v":10.408952,"d":"10.41"},{"v":10.989181,"d":"10.99"},{"v":11.402746,"d":"11.40"},{"v":1.07436008041126,"d":"1.07"},{"v":0.103477605203146,"d":"0.10"},{"v":0.903896410575681,"d":"0.90"},1,"up","no"]
[169883,0,"chr6","+",33454576,33457544,"ENST00000395064",2,2715,"ENSG00000213588","ZBTB9","GO:0003676(nucleic acid binding);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0005634(nucleus);GO:0046872(metal ion binding)","NA","K10496","NA","zinc finger and BTB domain containing 9 [Source:HGNC Symbol;Acc:HGNC:28323]",{"v":2.70526,"d":"2.71"},{"v":2.477813,"d":"2.48"},{"v":2.555655,"d":"2.56"},{"v":2.664526,"d":"2.66"},{"v":1.951363,"d":"1.95"},{"v":2.440498,"d":"2.44"},{"v":1.09669835285395,"d":"1.10"},{"v":0.133166766684523,"d":"0.13"},{"v":0.905689661345434,"d":"0.91"},1,"up","no"]
[51648,0,"chr13","-",47942656,48001354,"ENST00000378654",11,2192,"ENSG00000136143","SUCLA2","GO:0000166(nucleotide binding);GO:0000287(magnesium ion binding);GO:0003824(catalytic activity);GO:0004775(succinate-CoA ligase (ADP-forming) activity);GO:0005515(protein binding);GO:0005524(ATP binding);GO:0005739(mitochondrion);GO:0005759(mitochondrial matrix);GO:0006099(tricarboxylic acid cycle);GO:0006104(succinyl-CoA metabolic process);GO:0006105(succinate metabolic process);GO:0006781(succinyl-CoA pathway);GO:0016874(ligase activity);GO:0046872(metal ion binding);GO:0070062(extracellular exosome)","00020(Citrate cycle (TCA cycle));00640(Propanoate metabolism)","K01900","6.2.1.5;EC:6.2.1.4","succinate-CoA ligase ADP-forming beta subunit [Source:HGNC Symbol;Acc:HGNC:11448]",{"v":0.954824,"d":"0.95"},{"v":1.88677,"d":"1.89"},{"v":2.437316,"d":"2.44"},{"v":0.216975,"d":"0.22"},{"v":3.104892,"d":"3.10"},{"v":1.434638,"d":"1.43"},{"v":1.10982959126501,"d":"1.11"},{"v":0.150338175034598,"d":"0.15"},{"v":0.908950791392936,"d":"0.91"},1,"up","no"]
[11682,0,"chr1","-",154156613,154171423,"ENST00000651731",6,2796,"ENSG00000143549","TPM3","GO:0001725(stress fiber);GO:0003674(molecular_function);GO:0003779(actin binding);GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005856(cytoskeleton);GO:0005862(muscle thin filament tropomyosin);GO:0005884(actin filament);GO:0006936(muscle contraction);GO:0007015(actin filament organization);GO:0015629(actin cytoskeleton);GO:0030049(muscle filament sliding);GO:0051015(actin filament binding);GO:0070062(extracellular exosome)","04260(Cardiac muscle contraction);04261(Adrenergic signaling in cardiomyocytes);05200(Pathways in cancer);05216(Thyroid cancer);05410(Hypertrophic cardiomyopathy (HCM));05414(Dilated cardiomyopathy (DCM))","K09290","NA","tropomyosin 3 [Source:HGNC Symbol;Acc:HGNC:12012]",{"v":0.306949,"d":"0.31"},{"v":0.316603,"d":"0.32"},{"v":0.043591,"d":"0.04"},{"v":0.204189,"d":"0.20"},{"v":0.328363,"d":"0.33"},{"v":0.191957,"d":"0.19"},{"v":0.920820859368207,"d":"0.92"},{"v":-0.119007579655481,"d":"-0.12"},{"v":0.910663118576842,"d":"0.91"},1,"down","no"]
[166043,0,"chr5","+",177600132,177610330,"ENST00000029410",6,1698,"ENSG00000027847","B4GALT7","GO:0000139(Golgi membrane);GO:0003831(beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity);GO:0005515(protein binding);GO:0005794(Golgi apparatus);GO:0005975(carbohydrate metabolic process);GO:0006024(glycosaminoglycan biosynthetic process);GO:0006029(proteoglycan metabolic process);GO:0006464(cellular protein modification process);GO:0006486(protein glycosylation);GO:0006487(protein N-linked glycosylation);GO:0008378(galactosyltransferase activity);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016740(transferase activity);GO:0016757(transferase activity, transferring glycosyl groups);GO:0030145(manganese ion binding);GO:0030203(glycosaminoglycan metabolic process);GO:0032580(Golgi cisterna membrane);GO:0046525(xylosylprotein 4-beta-galactosyltransferase activity);GO:0046872(metal ion binding);GO:0048147(negative regulation of fibroblast proliferation);GO:0097435(supramolecular fiber organization)","00532(Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate);00534(Glycosaminoglycan biosynthesis - heparan sulfate / heparin)","NA","NA","beta-1,4-galactosyltransferase 7 [Source:HGNC Symbol;Acc:HGNC:930]",{"v":4.234007,"d":"4.23"},{"v":5.794904,"d":"5.79"},{"v":9.701967,"d":"9.70"},{"v":6.673753,"d":"6.67"},{"v":6.80989,"d":"6.81"},{"v":4.604439,"d":"4.60"},{"v":1.09082201197451,"d":"1.09"},{"v":0.125415718169314,"d":"0.13"},{"v":0.912172681864362,"d":"0.91"},1,"up","no"]
[181533,0,"chr7","-",97966377,97970404,"ENST00000650204",3,1910,"ENSG00000285725","AC004967","NA","NA","NA","NA","novel transcript",{"v":0.199265,"d":"0.20"},{"v":0.470601,"d":"0.47"},{"v":0.416801,"d":"0.42"},{"v":0.708891,"d":"0.71"},{"v":0.085999,"d":"0.09"},{"v":0.158971,"d":"0.16"},{"v":1.13922992972771,"d":"1.14"},{"v":0.188058954245713,"d":"0.19"},{"v":0.913549871699376,"d":"0.91"},1,"up","no"]
[28963,0,"chr11","-",33740939,33774347,"ENST00000526785",10,5798,"ENSG00000110429","FBXO3","GO:0004842(ubiquitin-protein transferase activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0006508(proteolysis);GO:0016567(protein ubiquitination)","NA","K10290","NA","F-box protein 3 [Source:HGNC Symbol;Acc:HGNC:13582]",{"v":0.510105,"d":"0.51"},{"v":0.519335,"d":"0.52"},{"v":2.897407,"d":"2.90"},{"v":0.837542,"d":"0.84"},{"v":2.543517,"d":"2.54"},{"v":0.776422,"d":"0.78"},{"v":0.944525543231587,"d":"0.94"},{"v":-0.0823382822914585,"d":"-0.08"},{"v":0.914886774628644,"d":"0.91"},1,"down","no"]
[3,0,"chr1","-",14404,29570,"ENST00000488147",11,1351,"ENSG00000227232","WASH7P","NA","NA","NA","NA","WAS protein family homolog 7, pseudogene [Source:HGNC Symbol;Acc:HGNC:38034]",{"v":8.53558,"d":"8.54"},{"v":8.124784,"d":"8.12"},{"v":7.873472,"d":"7.87"},{"v":7.429782,"d":"7.43"},{"v":7.676654,"d":"7.68"},{"v":7.626755,"d":"7.63"},{"v":1.07920775398403,"d":"1.08"},{"v":0.109972619034587,"d":"0.11"},{"v":0.91800896337126,"d":"0.92"},1,"up","no"]
[177435,0,"chr7","-",26189927,26191678,"ENST00000476233",2,1220,"ENSG00000122566","HNRNPA2B1","GO:0000122(negative regulation of transcription by RNA polymerase II);GO:0000398(mRNA splicing, via spliceosome);GO:0000781(chromosome, telomeric region);GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0003729(mRNA binding);GO:0003730(mRNA 3'-UTR binding);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005681(spliceosomal complex);GO:0005737(cytoplasm);GO:0006397(mRNA processing);GO:0006406(mRNA export from nucleus);GO:0008380(RNA splicing);GO:0015030(Cajal body);GO:0016020(membrane);GO:0016070(RNA metabolic process);GO:0016363(nuclear matrix);GO:0031053(primary miRNA processing);GO:0035198(miRNA binding);GO:0035722(interleukin-12-mediated signaling pathway);GO:0043047(single-stranded telomeric DNA binding);GO:0044806(G-quadruplex DNA unwinding);GO:0048025(negative regulation of mRNA splicing, via spliceosome);GO:0050658(RNA transport);GO:0051028(mRNA transport);GO:0070062(extracellular exosome);GO:0071013(catalytic step 2 spliceosome);GO:0097157(pre-mRNA intronic binding);GO:0098505(G-rich strand telomeric DNA binding);GO:1904358(positive regulation of telomere maintenance via telomere lengthening);GO:1905663(positive regulation of telomerase RNA reverse transcriptase activity);GO:1990247(N6-methyladenosine-containing RNA binding);GO:1990428(miRNA transport);GO:1990904(ribonucleoprotein complex)","NA","K13158","NA","heterogeneous nuclear ribonucleoprotein A2/B1 [Source:HGNC Symbol;Acc:HGNC:5033]",{"v":2.188142,"d":"2.19"},{"v":2.007502,"d":"2.01"},{"v":4.200188,"d":"4.20"},{"v":2.00634,"d":"2.01"},{"v":3.217945,"d":"3.22"},{"v":2.47881,"d":"2.48"},{"v":1.08992969708929,"d":"1.09"},{"v":0.124235080936452,"d":"0.12"},{"v":0.919657988223151,"d":"0.92"},1,"up","no"]
[157396,0,"chr5","-",6599569,6633042,"ENST00000506139",18,2619,"ENSG00000037474","NSUN2","GO:0000049(tRNA binding);GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005730(nucleolus);GO:0005737(cytoplasm);GO:0005819(spindle);GO:0005856(cytoskeleton);GO:0006400(tRNA modification);GO:0007049(cell cycle);GO:0007286(spermatid development);GO:0008033(tRNA processing);GO:0008168(methyltransferase activity);GO:0016428(tRNA (cytosine-5-)-methyltransferase activity);GO:0016740(transferase activity);GO:0030488(tRNA methylation);GO:0032259(methylation);GO:0033313(meiotic cell cycle checkpoint);GO:0033391(chromatoid body);GO:0048820(hair follicle maturation);GO:0051301(cell division)","NA","K15335","EC:2.1.1.203","NOP2/Sun RNA methyltransferase family member 2 [Source:HGNC Symbol;Acc:HGNC:25994]",{"v":9.962124,"d":"9.96"},{"v":6.599658,"d":"6.60"},{"v":6.566702,"d":"6.57"},{"v":7.685076,"d":"7.69"},{"v":7.301427,"d":"7.30"},{"v":6.651408,"d":"6.65"},{"v":1.06888710282615,"d":"1.07"},{"v":0.0961094818758604,"d":"0.10"},{"v":0.921223392860538,"d":"0.92"},1,"up","no"]
[102292,0,"chr19","-",34758073,34773215,"ENST00000329285",4,3102,"ENSG00000153896","ZNF599","GO:0000981(DNA-binding transcription factor activity, RNA polymerase II-specific);GO:0003676(nucleic acid binding);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0005622(intracellular);GO:0005634(nucleus);GO:0006355(regulation of transcription, DNA-templated);GO:0006357(regulation of transcription by RNA polymerase II);GO:0046872(metal ion binding)","05168(Herpes simplex virus 1 infection)","K09228","NA","zinc finger protein 599 [Source:HGNC Symbol;Acc:HGNC:26408]",{"v":0.185458,"d":"0.19"},{"v":0.658597,"d":"0.66"},{"v":0.37053,"d":"0.37"},{"v":0.495691,"d":"0.50"},{"v":0.346162,"d":"0.35"},{"v":0.430506,"d":"0.43"},{"v":0.95459300401852,"d":"0.95"},{"v":-0.0670423316218758,"d":"-0.07"},{"v":0.922771603671228,"d":"0.92"},1,"down","no"]
[161203,0,"chr5","+",96702789,96774679,"ENST00000395813",30,4356,"ENSG00000153113","CAST","GO:0002020(protease binding);GO:0003723(RNA binding);GO:0004866(endopeptidase inhibitor activity);GO:0004869(cysteine-type endopeptidase inhibitor activity);GO:0005515(protein binding);GO:0005783(endoplasmic reticulum);GO:0005829(cytosol);GO:0010466(negative regulation of peptidase activity);GO:0010859(calcium-dependent cysteine-type endopeptidase inhibitor activity);GO:0016020(membrane);GO:0030414(peptidase inhibitor activity);GO:0045296(cadherin binding);GO:0097340(inhibition of cysteine-type endopeptidase activity);GO:1990709(presynaptic active zone organization);GO:2000675(negative regulation of type B pancreatic cell apoptotic process)","NA","NA","NA","calpastatin [Source:HGNC Symbol;Acc:HGNC:1515]",{"v":50.518063,"d":"50.52"},{"v":44.872086,"d":"44.87"},{"v":49.264355,"d":"49.26"},{"v":42.178867,"d":"42.18"},{"v":48.015713,"d":"48.02"},{"v":46.510307,"d":"46.51"},{"v":1.0581516665165,"d":"1.06"},{"v":0.081546425986337,"d":"0.08"},{"v":0.924556256680866,"d":"0.92"},1,"up","no"]
[85605,0,"chr17","+",42020416,42025641,"ENST00000393879",2,4213,"ENSG00000168256","NKIRAS2","GO:0000166(nucleotide binding);GO:0003924(GTPase activity);GO:0005525(GTP binding);GO:0005575(cellular_component);GO:0005737(cytoplasm);GO:0007165(signal transduction);GO:0007249(I-kappaB kinase/NF-kappaB signaling);GO:0016020(membrane)","NA","K17197","NA","NFKB inhibitor interacting Ras like 2 [Source:HGNC Symbol;Acc:HGNC:17898]",{"v":3.142917,"d":"3.14"},{"v":2.91934,"d":"2.92"},{"v":0.569663,"d":"0.57"},{"v":3.254977,"d":"3.25"},{"v":0.443353,"d":"0.44"},{"v":2.405216,"d":"2.41"},{"v":1.08656836534041,"d":"1.09"},{"v":0.119778949700671,"d":"0.12"},{"v":0.927677944040825,"d":"0.93"},1,"up","no"]
[110949,0,"chr2","+",27771719,27779733,"ENST00000296102",4,508,"ENSG00000243147","MRPL33","GO:0003735(structural constituent of ribosome);GO:0005622(intracellular);GO:0005739(mitochondrion);GO:0005743(mitochondrial inner membrane);GO:0005762(mitochondrial large ribosomal subunit);GO:0005840(ribosome);GO:0006412(translation);GO:0070125(mitochondrial translational elongation);GO:0070126(mitochondrial translational termination)","03010(Ribosome)","K02913","NA","mitochondrial ribosomal protein L33 [Source:HGNC Symbol;Acc:HGNC:14487]",{"v":29.265049,"d":"29.27"},{"v":28.80409,"d":"28.80"},{"v":25.92387,"d":"25.92"},{"v":29.558681,"d":"29.56"},{"v":27.877943,"d":"27.88"},{"v":29.191668,"d":"29.19"},{"v":0.969579418696146,"d":"0.97"},{"v":-0.0445690199009056,"d":"-0.04"},{"v":0.929130530726278,"d":"0.93"},1,"down","no"]
[102872,0,"chr19","+",36114362,36115146,"ENST00000622994",1,785,"ENSG00000279504","AD001527","NA","NA","NA","NA","TEC",{"v":1.177794,"d":"1.18"},{"v":1.589263,"d":"1.59"},{"v":0.174213,"d":"0.17"},{"v":0.436422,"d":"0.44"},{"v":0.986252,"d":"0.99"},{"v":1.237773,"d":"1.24"},{"v":1.10555481841961,"d":"1.11"},{"v":0.144770562287891,"d":"0.14"},{"v":0.930578928363297,"d":"0.93"},1,"up","no"]
[32963,0,"chr11","+",67121269,67255062,"ENST00000308783",21,3666,"ENSG00000173120","KDM2A","GO:0000981(DNA-binding transcription factor activity, RNA polymerase II-specific);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0006303(double-strand break repair via nonhomologous end joining);GO:0006325(chromatin organization);GO:0006357(regulation of transcription by RNA polymerase II);GO:0008168(methyltransferase activity);GO:0008270(zinc ion binding);GO:0010944(negative regulation of transcription by competitive promoter binding);GO:0016491(oxidoreductase activity);GO:0032259(methylation);GO:0032922(circadian regulation of gene expression);GO:0042752(regulation of circadian rhythm);GO:0046872(metal ion binding);GO:0051213(dioxygenase activity);GO:0051864(histone demethylase activity (H3-K36 specific));GO:0055114(oxidation-reduction process);GO:0070544(histone H3-K36 demethylation)","NA","K10276","EC:1.14.11.27","lysine demethylase 2A [Source:HGNC Symbol;Acc:HGNC:13606]",{"v":0.034292,"d":"0.03"},{"v":0.219988,"d":"0.22"},{"v":0.285892,"d":"0.29"},{"v":0.159892,"d":"0.16"},{"v":0.06892,"d":"0.07"},{"v":0.254187,"d":"0.25"},{"v":1.11837084548829,"d":"1.12"},{"v":0.161398657083414,"d":"0.16"},{"v":0.932240086802529,"d":"0.93"},1,"up","no"]
[102868,0,"chr19","-",36113723,36115193,"ENST00000586789",5,993,"ENSG00000105258","POLR2I","GO:0000398(mRNA splicing, via spliceosome);GO:0001193(maintenance of transcriptional fidelity during DNA-templated transcription elongation from RNA polymerase II promoter);GO:0003676(nucleic acid binding);GO:0003899(DNA-directed 5'-3' RNA polymerase activity);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005665(RNA polymerase II, core complex);GO:0005730(nucleolus);GO:0006283(transcription-coupled nucleotide-excision repair);GO:0006351(transcription, DNA-templated);GO:0006366(transcription by RNA polymerase II);GO:0006367(transcription initiation from RNA polymerase II promoter);GO:0006368(transcription elongation from RNA polymerase II promoter);GO:0006370(7-methylguanosine mRNA capping);GO:0006379(mRNA cleavage);GO:0008270(zinc ion binding);GO:0008543(fibroblast growth factor receptor signaling pathway);GO:0016070(RNA metabolic process);GO:0035019(somatic stem cell population maintenance);GO:0042795(snRNA transcription by RNA polymerase II);GO:0046872(metal ion binding);GO:0050434(positive regulation of viral transcription);GO:0060964(regulation of gene silencing by miRNA)","03020(RNA polymerase);05016(Huntington disease)","NA","NA","RNA polymerase II subunit I [Source:HGNC Symbol;Acc:HGNC:9196]",{"v":1.80896,"d":"1.81"},{"v":1.067831,"d":"1.07"},{"v":1.471796,"d":"1.47"},{"v":1.576743,"d":"1.58"},{"v":1.098479,"d":"1.10"},{"v":1.834242,"d":"1.83"},{"v":0.964324584917409,"d":"0.96"},{"v":-0.0524092656183717,"d":"-0.05"},{"v":0.93360649610402,"d":"0.93"},1,"down","no"]
[53578,0,"chr13","+",113208772,113265077,"ENST00000451881",20,3724,"ENSG00000139842","CUL4A","GO:0000082(G1/S transition of mitotic cell cycle);GO:0000715(nucleotide-excision repair, DNA damage recognition);GO:0000717(nucleotide-excision repair, DNA duplex unwinding);GO:0001701(in utero embryonic development);GO:0005515(protein binding);GO:0005654(nucleoplasm);GO:0006281(DNA repair);GO:0006283(transcription-coupled nucleotide-excision repair);GO:0006293(nucleotide-excision repair, preincision complex stabilization);GO:0006294(nucleotide-excision repair, preincision complex assembly);GO:0006295(nucleotide-excision repair, DNA incision, 3'-to lesion);GO:0006296(nucleotide-excision repair, DNA incision, 5'-to lesion);GO:0006511(ubiquitin-dependent protein catabolic process);GO:0006974(cellular response to DNA damage stimulus);GO:0007050(cell cycle arrest);GO:0008284(positive regulation of cell population proliferation);GO:0008285(negative regulation of cell population proliferation);GO:0016032(viral process);GO:0016567(protein ubiquitination);GO:0019005(SCF ubiquitin ligase complex);GO:0030097(hemopoiesis);GO:0030853(negative regulation of granulocyte differentiation);GO:0031146(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process);GO:0031461(cullin-RING ubiquitin ligase complex);GO:0031464(Cul4A-RING E3 ubiquitin ligase complex);GO:0031625(ubiquitin protein ligase binding);GO:0033683(nucleotide-excision repair, DNA incision);GO:0035019(somatic stem cell population maintenance);GO:0042769(DNA damage response, detection of DNA damage);GO:0043161(proteasome-mediated ubiquitin-dependent protein catabolic process);GO:0043687(post-translational protein modification);GO:0051246(regulation of protein metabolic process);GO:0061630(ubiquitin protein ligase activity);GO:0070911(global genome nucleotide-excision repair);GO:0080008(Cul4-RING E3 ubiquitin ligase complex);GO:0097193(intrinsic apoptotic signaling pathway);GO:1900087(positive regulation of G1/S transition of mitotic cell cycle);GO:2000001(regulation of DNA damage checkpoint);GO:2000819(regulation of nucleotide-excision repair)","03420(Nucleotide excision repair);04120(Ubiquitin mediated proteolysis);05170(Human immunodeficiency virus 1 infection)","NA","NA","cullin 4A [Source:HGNC Symbol;Acc:HGNC:2554]",{"v":0.301167,"d":"0.30"},{"v":24.334908,"d":"24.33"},{"v":0.303194,"d":"0.30"},{"v":26.256203,"d":"26.26"},{"v":0.004304,"d":"0.00"},{"v":0.203667,"d":"0.20"},{"v":0.942378515195676,"d":"0.94"},{"v":-0.0856214466081885,"d":"-0.09"},{"v":0.936988258184688,"d":"0.94"},1,"down","no"]
[7875,0,"chr1","-",84554853,84574421,"ENST00000370625",7,1633,"ENSG00000117151","CTBS","GO:0004553(hydrolase activity, hydrolyzing O-glycosyl compounds);GO:0004568(chitinase activity);GO:0005615(extracellular space);GO:0005764(lysosome);GO:0005975(carbohydrate metabolic process);GO:0006032(chitin catabolic process);GO:0008061(chitin binding);GO:0008152(metabolic process);GO:0009313(oligosaccharide catabolic process);GO:0016787(hydrolase activity);GO:0016798(hydrolase activity, acting on glycosyl bonds)","NA","NA","NA","chitobiase [Source:HGNC Symbol;Acc:HGNC:2496]",{"v":3.377258,"d":"3.38"},{"v":2.936671,"d":"2.94"},{"v":3.288208,"d":"3.29"},{"v":4.964223,"d":"4.96"},{"v":2.74129,"d":"2.74"},{"v":2.193664,"d":"2.19"},{"v":0.969993465113312,"d":"0.97"},{"v":-0.0439530670519019,"d":"-0.04"},{"v":0.938396283709662,"d":"0.94"},1,"down","no"]
[199643,0,"chr9","-",128635918,128656699,"ENST00000451652",4,1039,"ENSG00000119333","WDR34","GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0005814(centriole);GO:0005829(cytosol);GO:0005856(cytoskeleton);GO:0005868(cytoplasmic dynein complex);GO:0005929(cilium);GO:0005930(axoneme);GO:0007018(microtubule-based movement);GO:0008574(ATP-dependent microtubule motor activity, plus-end-directed);GO:0030286(dynein complex);GO:0035735(intraciliary transport involved in cilium assembly);GO:0036064(ciliary basal body);GO:0042073(intraciliary transport);GO:0042995(cell projection);GO:0045503(dynein light chain binding);GO:0045504(dynein heavy chain binding);GO:0060271(cilium assembly);GO:0097014(ciliary plasm);GO:0097542(ciliary tip)","NA","K22868","NA","WD repeat domain 34 [Source:HGNC Symbol;Acc:HGNC:28296]",{"v":0.527989,"d":"0.53"},{"v":1.092696,"d":"1.09"},{"v":0.453468,"d":"0.45"},{"v":0.288037,"d":"0.29"},{"v":0.451555,"d":"0.45"},{"v":1.166885,"d":"1.17"},{"v":1.08795070698466,"d":"1.09"},{"v":0.121613192250209,"d":"0.12"},{"v":0.939972966486391,"d":"0.94"},1,"up","no"]
[206021,0,"chrX","-",130064928,130110495,"ENST00000308167",9,4165,"ENSG00000102034","ELF4","GO:0000978(RNA polymerase II proximal promoter sequence-specific DNA binding);GO:0000981(DNA-binding transcription factor activity, RNA polymerase II-specific);GO:0001228(DNA-binding transcription activator activity, RNA polymerase II-specific);GO:0001787(natural killer cell proliferation);GO:0001866(NK T cell proliferation);GO:0003677(DNA binding);GO:0003700(DNA-binding transcription factor activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0006355(regulation of transcription, DNA-templated);GO:0006357(regulation of transcription by RNA polymerase II);GO:0016604(nuclear body);GO:0016605(PML body);GO:0030154(cell differentiation);GO:0043565(sequence-specific DNA binding);GO:0045087(innate immune response);GO:0045893(positive regulation of transcription, DNA-templated);GO:0045944(positive regulation of transcription by RNA polymerase II)","NA","NA","NA","E74 like ETS transcription factor 4 [Source:HGNC Symbol;Acc:HGNC:3319]",{"v":0.198606,"d":"0.20"},{"v":0.069497,"d":"0.07"},{"v":0.126557,"d":"0.13"},{"v":0.110576,"d":"0.11"},{"v":0.095517,"d":"0.10"},{"v":0.213656,"d":"0.21"},{"v":0.940228565166325,"d":"0.94"},{"v":-0.0889165830455888,"d":"-0.09"},{"v":0.941390402169862,"d":"0.94"},1,"down","no"]
[190431,0,"chr8","+",81280867,81284777,"ENST00000396359",4,986,"ENSG00000164687","FABP5","GO:0001972(retinoic acid binding);GO:0005504(fatty acid binding);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0005615(extracellular space);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0006006(glucose metabolic process);GO:0006629(lipid metabolic process);GO:0006656(phosphatidylcholine biosynthetic process);GO:0008289(lipid binding);GO:0008544(epidermis development);GO:0010829(negative regulation of glucose transmembrane transport);GO:0014069(postsynaptic density);GO:0016020(membrane);GO:0019433(triglyceride catabolic process);GO:0030054(cell junction);GO:0030667(secretory granule membrane);GO:0031392(regulation of prostaglandin biosynthetic process);GO:0035360(positive regulation of peroxisome proliferator activated receptor signaling pathway);GO:0035578(azurophil granule lumen);GO:0042593(glucose homeostasis);GO:0042802(identical protein binding);GO:0043312(neutrophil degranulation);GO:0045202(synapse);GO:0045211(postsynaptic membrane);GO:0051930(regulation of sensory perception of pain);GO:0070062(extracellular exosome);GO:0099178(regulation of retrograde trans-synaptic signaling by endocanabinoid);GO:0120162(positive regulation of cold-induced thermogenesis)","03320(PPAR signaling pathway)","K08754","NA","fatty acid binding protein 5 [Source:HGNC Symbol;Acc:HGNC:3560]",{"v":0.064255,"d":"0.06"},{"v":1.440344,"d":"1.44"},{"v":0.2381,"d":"0.24"},{"v":0.243922,"d":"0.24"},{"v":0.173951,"d":"0.17"},{"v":1.160275,"d":"1.16"},{"v":1.10426842095925,"d":"1.10"},{"v":0.143090899034073,"d":"0.14"},{"v":0.942913432540711,"d":"0.94"},1,"up","no"]
[36714,0,"chr11","+",117292798,117293571,"ENST00000618857",1,774,"ENSG00000278768","BACE1-AS","NA","NA","NA","NA","BACE1 antisense RNA [Source:HGNC Symbol;Acc:HGNC:37125]",{"v":2.114318,"d":"2.11"},{"v":1.741079,"d":"1.74"},{"v":2.194852,"d":"2.19"},{"v":2.333995,"d":"2.33"},{"v":1.704597,"d":"1.70"},{"v":1.619928,"d":"1.62"},{"v":1.06922817273775,"d":"1.07"},{"v":0.0965697562865638,"d":"0.10"},{"v":0.944318986400938,"d":"0.94"},1,"up","no"]
[48979,0,"chr12","-",121308245,121352411,"ENST00000261819",17,2574,"ENSG00000089053","ANAPC5","GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005680(anaphase-promoting complex);GO:0005829(cytosol);GO:0006511(ubiquitin-dependent protein catabolic process);GO:0007049(cell cycle);GO:0016567(protein ubiquitination);GO:0019903(protein phosphatase binding);GO:0031145(anaphase-promoting complex-dependent catabolic process);GO:0045842(positive regulation of mitotic metaphase/anaphase transition);GO:0051301(cell division);GO:0061630(ubiquitin protein ligase activity);GO:0070979(protein K11-linked ubiquitination);GO:1901990(regulation of mitotic cell cycle phase transition)","04110(Cell cycle);04114(Oocyte meiosis);04120(Ubiquitin mediated proteolysis);04657(IL-17 signaling pathway);04914(Progesterone-mediated oocyte maturation);05166(Human T-cell leukemia virus 1 infection)","K03352","NA","anaphase promoting complex subunit 5 [Source:HGNC Symbol;Acc:HGNC:15713]",{"v":4.984629,"d":"4.98"},{"v":4.06438,"d":"4.06"},{"v":4.836413,"d":"4.84"},{"v":4.217649,"d":"4.22"},{"v":5.615651,"d":"5.62"},{"v":4.340371,"d":"4.34"},{"v":0.979663066822985,"d":"0.98"},{"v":-0.0296424430107503,"d":"-0.03"},{"v":0.94792823507342,"d":"0.95"},1,"down","no"]
[135264,0,"chr22","-",42574733,42582001,"ENST00000566851",7,833,"ENSG00000182841","RRP7BP","NA","NA","NA","NA","ribosomal RNA processing 7 homolog B, pseudogene [Source:HGNC Symbol;Acc:HGNC:30454]",{"v":0.322169,"d":"0.32"},{"v":2.987939,"d":"2.99"},{"v":0.956073,"d":"0.96"},{"v":1.755914,"d":"1.76"},{"v":0.92247,"d":"0.92"},{"v":1.288911,"d":"1.29"},{"v":1.07533747805495,"d":"1.08"},{"v":0.104789498427508,"d":"0.10"},{"v":0.949293300126703,"d":"0.95"},1,"up","no"]
[134611,0,"chr22","-",38296205,38317411,"ENST00000413574",8,1631,"ENSG00000213923","CSNK1E","GO:0000086(G2/M transition of mitotic cell cycle);GO:0000166(nucleotide binding);GO:0003723(RNA binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005515(protein binding);GO:0005524(ATP binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0006281(DNA repair);GO:0006468(protein phosphorylation);GO:0006897(endocytosis);GO:0007165(signal transduction);GO:0010389(regulation of G2/M transition of mitotic cell cycle);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0016740(transferase activity);GO:0018105(peptidyl-serine phosphorylation);GO:0018107(peptidyl-threonine phosphorylation);GO:0032091(negative regulation of protein binding);GO:0032436(positive regulation of proteasomal ubiquitin-dependent protein catabolic process);GO:0032922(circadian regulation of gene expression);GO:0042752(regulation of circadian rhythm);GO:0048511(rhythmic process);GO:0060070(canonical Wnt signaling pathway);GO:0090263(positive regulation of canonical Wnt signaling pathway);GO:0097711(ciliary basal body-plasma membrane docking);GO:1903827(regulation of cellular protein localization);GO:1905426(positive regulation of Wnt-mediated midbrain dopaminergic neuron differentiation);GO:2000052(positive regulation of non-canonical Wnt signaling pathway)","04068(FoxO signaling pathway);04310(Wnt signaling pathway);04340(Hedgehog signaling pathway);04390(Hippo signaling pathway);04392(Hippo signaling pathway - multiple species);04710(Circadian rhythm)","NA","NA","casein kinase 1 epsilon [Source:HGNC Symbol;Acc:HGNC:2453]",{"v":7.70817,"d":"7.71"},{"v":4.383727,"d":"4.38"},{"v":6.234171,"d":"6.23"},{"v":1.928686,"d":"1.93"},{"v":7.400182,"d":"7.40"},{"v":8.102002,"d":"8.10"},{"v":1.05135704643543,"d":"1.05"},{"v":0.0722526994094798,"d":"0.07"},{"v":0.950811814038961,"d":"0.95"},1,"up","no"]
[171304,0,"chr6","-",52977948,52988002,"ENST00000486559",5,1698,"ENSG00000170899","GSTA4","GO:0004364(glutathione transferase activity);GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0006749(glutathione metabolic process);GO:0006805(xenobiotic metabolic process);GO:0016740(transferase activity);GO:0042802(identical protein binding);GO:0042803(protein homodimerization activity);GO:1901687(glutathione derivative biosynthetic process)","00480(Glutathione metabolism);00980(Metabolism of xenobiotics by cytochrome P450);00982(Drug metabolism - cytochrome P450);00983(Drug metabolism - other enzymes);01524(Platinum drug resistance);05200(Pathways in cancer);05204(Chemical carcinogenesis);05225(Hepatocellular carcinoma);05418(Fluid shear stress and atherosclerosis)","K00799","EC:2.5.1.18","glutathione S-transferase alpha 4 [Source:HGNC Symbol;Acc:HGNC:4629]",{"v":3.400847,"d":"3.40"},{"v":2.142241,"d":"2.14"},{"v":2.487587,"d":"2.49"},{"v":2.34035,"d":"2.34"},{"v":3.428318,"d":"3.43"},{"v":1.833419,"d":"1.83"},{"v":1.0563776762881,"d":"1.06"},{"v":0.0791257194454155,"d":"0.08"},{"v":0.952239596195623,"d":"0.95"},1,"up","no"]
[185404,0,"chr7","+",151037688,151045562,"ENST00000482899",7,3743,"ENSG00000197150","ABCB8","GO:0000166(nucleotide binding);GO:0005215(transporter activity);GO:0005524(ATP binding);GO:0005634(nucleus);GO:0005730(nucleolus);GO:0005739(mitochondrion);GO:0005740(mitochondrial envelope);GO:0005743(mitochondrial inner membrane);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016887(ATPase activity);GO:0042626(ATPase activity, coupled to transmembrane movement of substances);GO:0043190(ATP-binding cassette (ABC) transporter complex);GO:0055085(transmembrane transport)","02010(ABC transporters)","K05655","NA","ATP binding cassette subfamily B member 8 [Source:HGNC Symbol;Acc:HGNC:49]",{"v":0.830385,"d":"0.83"},{"v":1.204981,"d":"1.20"},{"v":0.73103,"d":"0.73"},{"v":1.056929,"d":"1.06"},{"v":0.801551,"d":"0.80"},{"v":0.743826,"d":"0.74"},{"v":1.06305561298325,"d":"1.06"},{"v":0.0882170723877936,"d":"0.09"},{"v":0.953934570036134,"d":"0.95"},1,"up","no"]
[166956,0,"chr6","+",4040849,4064983,"ENST00000463634",17,2590,"ENSG00000112739","PRPF4B","GO:0000166(nucleotide binding);GO:0000398(mRNA splicing, via spliceosome);GO:0003723(RNA binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005515(protein binding);GO:0005524(ATP binding);GO:0005634(nucleus);GO:0005681(spliceosomal complex);GO:0005694(chromosome);GO:0006397(mRNA processing);GO:0006468(protein phosphorylation);GO:0008380(RNA splicing);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0016607(nuclear speck);GO:0016740(transferase activity);GO:0071013(catalytic step 2 spliceosome)","NA","K08827","EC:2.7.11.1","pre-mRNA processing factor 4B [Source:HGNC Symbol;Acc:HGNC:17346]",{"v":0.219744,"d":"0.22"},{"v":0.345425,"d":"0.35"},{"v":0.770456,"d":"0.77"},{"v":0.281743,"d":"0.28"},{"v":0.296044,"d":"0.30"},{"v":0.674832,"d":"0.67"},{"v":1.06626595956153,"d":"1.07"},{"v":0.0925673355486809,"d":"0.09"},{"v":0.95712810420559,"d":"0.96"},1,"up","no"]
[127203,0,"chr20","+",45363139,45376798,"ENST00000426004",4,2915,"ENSG00000204070","SYS1","GO:0000139(Golgi membrane);GO:0005794(Golgi apparatus);GO:0005802(trans-Golgi network);GO:0005829(cytosol);GO:0006895(Golgi to endosome transport);GO:0015031(protein transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0030173(integral component of Golgi membrane);GO:0032588(trans-Golgi network membrane);GO:0034067(protein localization to Golgi apparatus);GO:0043001(Golgi to plasma membrane protein transport)","NA","K20318","NA","SYS1, golgi trafficking protein [Source:HGNC Symbol;Acc:HGNC:16162]",{"v":0.380269,"d":"0.38"},{"v":0.412833,"d":"0.41"},{"v":0.346026,"d":"0.35"},{"v":0.385051,"d":"0.39"},{"v":0.3129,"d":"0.31"},{"v":0.463059,"d":"0.46"},{"v":0.981152617117854,"d":"0.98"},{"v":-0.0274505314970481,"d":"-0.03"},{"v":0.958582743889909,"d":"0.96"},1,"down","no"]
[148583,0,"chr3","+",196712358,196736007,"ENST00000392391",6,3057,"ENSG00000163964","PIGX","GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0006506(GPI anchor biosynthetic process);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016254(preassembly of GPI anchor in ER membrane)","00563(Glycosylphosphatidylinositol (GPI)-anchor biosynthesis)","K07541","NA","phosphatidylinositol glycan anchor biosynthesis class X [Source:HGNC Symbol;Acc:HGNC:26046]",{"v":4.926324,"d":"4.93"},{"v":5.181774,"d":"5.18"},{"v":4.210642,"d":"4.21"},{"v":5.588871,"d":"5.59"},{"v":4.150781,"d":"4.15"},{"v":4.70986,"d":"4.71"},{"v":0.990949728959705,"d":"0.99"},{"v":-0.0131162237723955,"d":"-0.01"},{"v":0.959975948924749,"d":"0.96"},1,"down","no"]
[76922,0,"chr16","+",69339772,69343106,"ENST00000254940",5,2055,"ENSG00000132603","NIP7","GO:0003723(RNA binding);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005730(nucleolus);GO:0005829(cytosol);GO:0030687(preribosome, large subunit precursor);GO:0042254(ribosome biogenesis);GO:0042255(ribosome assembly);GO:0042273(ribosomal large subunit biogenesis)","NA","K07565","NA","NIP7, nucleolar pre-rRNA processing protein [Source:HGNC Symbol;Acc:HGNC:24328]",{"v":7.217028,"d":"7.22"},{"v":6.88431,"d":"6.88"},{"v":6.957227,"d":"6.96"},{"v":6.796526,"d":"6.80"},{"v":7.093598,"d":"7.09"},{"v":7.366297,"d":"7.37"},{"v":0.990691941978379,"d":"0.99"},{"v":-0.0134915772049723,"d":"-0.01"},{"v":0.961462710625764,"d":"0.96"},1,"down","no"]
[93450,0,"chr18","+",21741320,21870957,"ENST00000261537",21,9576,"ENSG00000101752","MIB1","GO:0001568(blood vessel development);GO:0001701(in utero embryonic development);GO:0001756(somitogenesis);GO:0001841(neural tube formation);GO:0001947(heart looping);GO:0004842(ubiquitin-protein transferase activity);GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0005813(centrosome);GO:0005815(microtubule organizing center);GO:0005829(cytosol);GO:0005856(cytoskeleton);GO:0005886(plasma membrane);GO:0006897(endocytosis);GO:0007219(Notch signaling pathway);GO:0007507(heart development);GO:0008270(zinc ion binding);GO:0014069(postsynaptic density);GO:0016020(membrane);GO:0016567(protein ubiquitination);GO:0016740(transferase activity);GO:0031410(cytoplasmic vesicle);GO:0045665(negative regulation of neuron differentiation);GO:0045807(positive regulation of endocytosis);GO:0046872(metal ion binding)","NA","K10645","EC:2.3.2.27","mindbomb E3 ubiquitin protein ligase 1 [Source:HGNC Symbol;Acc:HGNC:21086]",{"v":8.032483,"d":"8.03"},{"v":8.290588,"d":"8.29"},{"v":7.999976,"d":"8.00"},{"v":8.196268,"d":"8.20"},{"v":8.126858,"d":"8.13"},{"v":8.071346,"d":"8.07"},{"v":0.997072082560344,"d":"1.00"},{"v":-0.00423028796379113,"d":"-0.00"},{"v":0.962597949234206,"d":"0.96"},1,"down","no"]
[129384,0,"chr21","+",18857779,18858276,"ENST00000358455",1,498,"ENSG00000198618","PPIAP22","NA","NA","NA","NA","peptidylprolyl isomerase A pseudogene 22 [Source:HGNC Symbol;Acc:HGNC:17236]",{"v":29.066553,"d":"29.07"},{"v":26.218904,"d":"26.22"},{"v":23.966522,"d":"23.97"},{"v":26.282978,"d":"26.28"},{"v":28.800259,"d":"28.80"},{"v":24.733524,"d":"24.73"},{"v":0.99292401755065,"d":"0.99"},{"v":-0.0102447736060427,"d":"-0.01"},{"v":0.965767035943313,"d":"0.97"},1,"down","no"]
[182554,0,"chr7","+",103297453,103310475,"ENST00000456433",8,904,"ENSG00000105819","PMPCB","GO:0003824(catalytic activity);GO:0004175(endopeptidase activity);GO:0004222(metalloendopeptidase activity);GO:0005739(mitochondrion);GO:0005743(mitochondrial inner membrane);GO:0005759(mitochondrial matrix);GO:0006508(proteolysis);GO:0006627(protein processing involved in protein targeting to mitochondrion);GO:0006851(mitochondrial calcium ion transmembrane transport);GO:0008233(peptidase activity);GO:0008237(metallopeptidase activity);GO:0016787(hydrolase activity);GO:0017087(mitochondrial processing peptidase complex);GO:0046872(metal ion binding)","NA","K17732","EC:3.4.24.64","peptidase, mitochondrial processing beta subunit [Source:HGNC Symbol;Acc:HGNC:9119]",{"v":2.127602,"d":"2.13"},{"v":1.324746,"d":"1.32"},{"v":2.577114,"d":"2.58"},{"v":1.426926,"d":"1.43"},{"v":2.297158,"d":"2.30"},{"v":2.402129,"d":"2.40"},{"v":0.984207046016846,"d":"0.98"},{"v":-0.0229662500133206,"d":"-0.02"},{"v":0.967294467772724,"d":"0.97"},1,"down","no"]
[131791,0,"chr22","+",19431902,19436075,"ENST00000333130",4,1387,"ENSG00000185608","MRPL40","GO:0003723(RNA binding);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005739(mitochondrion);GO:0005743(mitochondrial inner membrane);GO:0005761(mitochondrial ribosome);GO:0005762(mitochondrial large ribosomal subunit);GO:0005840(ribosome);GO:0009653(anatomical structure morphogenesis);GO:0070125(mitochondrial translational elongation);GO:0070126(mitochondrial translational termination)","NA","K17421","NA","mitochondrial ribosomal protein L40 [Source:HGNC Symbol;Acc:HGNC:14491]",{"v":20.373575,"d":"20.37"},{"v":17.866865,"d":"17.87"},{"v":17.451857,"d":"17.45"},{"v":16.681957,"d":"16.68"},{"v":18.062328,"d":"18.06"},{"v":19.025818,"d":"19.03"},{"v":1.03574837861107,"d":"1.04"},{"v":0.0506735618844808,"d":"0.05"},{"v":0.969009643517778,"d":"0.97"},1,"up","no"]
[4121,0,"chr1","-",33145399,33182043,"ENST00000291416",5,3817,"ENSG00000116525","TRIM62","GO:0004842(ubiquitin-protein transferase activity);GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0008270(zinc ion binding);GO:0010719(negative regulation of epithelial to mesenchymal transition);GO:0016567(protein ubiquitination);GO:0016740(transferase activity);GO:0032897(negative regulation of viral transcription);GO:0043123(positive regulation of I-kappaB kinase/NF-kappaB signaling);GO:0045087(innate immune response);GO:0046596(regulation of viral entry into host cell);GO:0046872(metal ion binding);GO:0051091(positive regulation of DNA-binding transcription factor activity);GO:0051092(positive regulation of NF-kappaB transcription factor activity);GO:0060333(interferon-gamma-mediated signaling pathway);GO:1902186(regulation of viral release from host cell)","NA","K12030","EC:2.3.2.27","tripartite motif containing 62 [Source:HGNC Symbol;Acc:HGNC:25574]",{"v":1.408665,"d":"1.41"},{"v":1.678356,"d":"1.68"},{"v":1.591346,"d":"1.59"},{"v":1.416771,"d":"1.42"},{"v":1.442326,"d":"1.44"},{"v":1.849916,"d":"1.85"},{"v":0.993492054492098,"d":"0.99"},{"v":-0.00941966540002124,"d":"-0.01"},{"v":0.970672649412481,"d":"0.97"},1,"down","no"]
[175704,0,"chr6","+",166999408,167040317,"ENST00000349556",12,1484,"ENSG00000213066","FGFR1OP","GO:0000086(G2/M transition of mitotic cell cycle);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005813(centrosome);GO:0005814(centriole);GO:0005815(microtubule organizing center);GO:0005829(cytosol);GO:0005856(cytoskeleton);GO:0006469(negative regulation of protein kinase activity);GO:0008284(positive regulation of cell population proliferation);GO:0010389(regulation of G2/M transition of mitotic cell cycle);GO:0019901(protein kinase binding);GO:0030030(cell projection organization);GO:0030292(protein tyrosine kinase inhibitor activity);GO:0030307(positive regulation of cell growth);GO:0030335(positive regulation of cell migration);GO:0034453(microtubule anchoring);GO:0042803(protein homodimerization activity);GO:0042995(cell projection);GO:0048471(perinuclear region of cytoplasm);GO:0061099(negative regulation of protein tyrosine kinase activity);GO:0097711(ciliary basal body-plasma membrane docking)","NA","K16546","NA","FGFR1 oncogene partner [Source:HGNC Symbol;Acc:HGNC:17012]",{"v":2.093056,"d":"2.09"},{"v":2.244985,"d":"2.24"},{"v":2.078168,"d":"2.08"},{"v":1.995488,"d":"2.00"},{"v":2.596813,"d":"2.60"},{"v":1.873373,"d":"1.87"},{"v":0.99234959881986,"d":"0.99"},{"v":-0.0110796319052677,"d":"-0.01"},{"v":0.971979318875035,"d":"0.97"},1,"down","no"]
[161418,0,"chr5","-",103086000,103120138,"ENST00000399004",8,3549,"ENSG00000145723","GIN1","GO:0003676(nucleic acid binding);GO:0015074(DNA integration)","NA","NA","NA","gypsy retrotransposon integrase 1 [Source:HGNC Symbol;Acc:HGNC:25959]",{"v":0.807387,"d":"0.81"},{"v":0.73446,"d":"0.73"},{"v":1.057227,"d":"1.06"},{"v":0.887274,"d":"0.89"},{"v":1.028544,"d":"1.03"},{"v":0.57608,"d":"0.58"},{"v":1.04300978611484,"d":"1.04"},{"v":0.0607526941118655,"d":"0.06"},{"v":0.975352754723454,"d":"0.98"},1,"up","no"]
[56836,0,"chr14","+",55129256,55142755,"ENST00000553755",4,630,"ENSG00000131981","LGALS3","GO:0001772(immunological synapse);GO:0002376(immune system process);GO:0002548(monocyte chemotaxis);GO:0003723(RNA binding);GO:0004864(protein phosphatase inhibitor activity);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0005615(extracellular space);GO:0005634(nucleus);GO:0005681(spliceosomal complex);GO:0005737(cytoplasm);GO:0005743(mitochondrial inner membrane);GO:0005886(plasma membrane);GO:0006397(mRNA processing);GO:0008380(RNA splicing);GO:0009986(cell surface);GO:0016020(membrane);GO:0019863(IgE binding);GO:0019903(protein phosphatase binding);GO:0030154(cell differentiation);GO:0030246(carbohydrate binding);GO:0030593(neutrophil chemotaxis);GO:0030667(secretory granule membrane);GO:0030855(epithelial cell differentiation);GO:0042056(chemoattractant activity);GO:0042129(regulation of T cell proliferation);GO:0043236(laminin binding);GO:0043312(neutrophil degranulation);GO:0045087(innate immune response);GO:0045637(regulation of myeloid cell differentiation);GO:0045806(negative regulation of endocytosis);GO:0048245(eosinophil chemotaxis);GO:0048246(macrophage chemotaxis);GO:0050860(negative regulation of T cell receptor signaling pathway);GO:0050918(positive chemotaxis);GO:0062023(collagen-containing extracellular matrix);GO:0070062(extracellular exosome);GO:0070232(regulation of T cell apoptotic process);GO:0071674(mononuclear cell migration);GO:0071677(positive regulation of mononuclear cell migration);GO:0090073(positive regulation of protein homodimerization activity);GO:0090280(positive regulation of calcium ion import);GO:0101003(ficolin-1-rich granule membrane);GO:1902041(regulation of extrinsic apoptotic signaling pathway via death domain receptors);GO:1903078(positive regulation of protein localization to plasma membrane);GO:1903614(negative regulation of protein tyrosine phosphatase activity);GO:2000521(negative regulation of immunological synapse formation);GO:2001189(negative regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell);GO:2001237(negative regulation of extrinsic apoptotic signaling pathway)","NA","K06831","NA","galectin 3 [Source:HGNC Symbol;Acc:HGNC:6563]",{"v":11.486982,"d":"11.49"},{"v":11.079552,"d":"11.08"},{"v":10.637494,"d":"10.64"},{"v":12.454683,"d":"12.45"},{"v":8.724288,"d":"8.72"},{"v":10.820883,"d":"10.82"},{"v":1.03763060918965,"d":"1.04"},{"v":0.0532929435638313,"d":"0.05"},{"v":0.976773732358044,"d":"0.98"},1,"up","no"]
[122741,0,"chr2","+",227325239,227357833,"ENST00000353339",11,2186,"ENSG00000168958","MFF","GO:0000266(mitochondrial fission);GO:0001836(release of cytochrome c from mitochondria);GO:0005515(protein binding);GO:0005739(mitochondrion);GO:0005741(mitochondrial outer membrane);GO:0005777(peroxisome);GO:0006626(protein targeting to mitochondrion);GO:0008021(synaptic vesicle);GO:0008053(mitochondrial fusion);GO:0010821(regulation of mitochondrion organization);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016559(peroxisome fission);GO:0030054(cell junction);GO:0031410(cytoplasmic vesicle);GO:0032592(integral component of mitochondrial membrane);GO:0042803(protein homodimerization activity);GO:0043653(mitochondrial fragmentation involved in apoptotic process);GO:0045202(synapse);GO:0051260(protein homooligomerization);GO:0070584(mitochondrion morphogenesis);GO:0090141(positive regulation of mitochondrial fission);GO:0090200(positive regulation of release of cytochrome c from mitochondria);GO:0090314(positive regulation of protein targeting to membrane);GO:1900063(regulation of peroxisome organization)","NA","K22076","NA","mitochondrial fission factor [Source:HGNC Symbol;Acc:HGNC:24858]",{"v":3.233565,"d":"3.23"},{"v":3.509818,"d":"3.51"},{"v":3.277507,"d":"3.28"},{"v":3.130414,"d":"3.13"},{"v":3.599749,"d":"3.60"},{"v":2.945384,"d":"2.95"},{"v":1.03569234897004,"d":"1.04"},{"v":0.0505955160256762,"d":"0.05"},{"v":0.978189773302549,"d":"0.98"},1,"up","no"]
[183621,0,"chr7","+",127652194,128092593,"ENST00000354725",24,3448,"ENSG00000197157","SND1","GO:0001649(osteoblast differentiation);GO:0003676(nucleic acid binding);GO:0003712(transcription coregulator activity);GO:0003723(RNA binding);GO:0004518(nuclease activity);GO:0004519(endonuclease activity);GO:0004521(endoribonuclease activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0006401(RNA catabolic process);GO:0010564(regulation of cell cycle process);GO:0010587(miRNA catabolic process);GO:0016020(membrane);GO:0016032(viral process);GO:0016442(RISC complex);GO:0016787(hydrolase activity);GO:0031047(gene silencing by RNA);GO:0042470(melanosome);GO:0045296(cadherin binding);GO:0070062(extracellular exosome);GO:0090305(nucleic acid phosphodiester bond hydrolysis);GO:0090502(RNA phosphodiester bond hydrolysis, endonucleolytic);GO:0097433(dense body);GO:1903506(regulation of nucleic acid-templated transcription);GO:1905172(RISC complex binding)","05203(Viral carcinogenesis)","K15979","NA","staphylococcal nuclease and tudor domain containing 1 [Source:HGNC Symbol;Acc:HGNC:30646]",{"v":64.438858,"d":"64.44"},{"v":65.164162,"d":"65.16"},{"v":65.266052,"d":"65.27"},{"v":65.275543,"d":"65.28"},{"v":65.049622,"d":"65.05"},{"v":63.189137,"d":"63.19"},{"v":1.00700087789894,"d":"1.01"},{"v":0.0100649410804382,"d":"0.01"},{"v":0.97986895383021,"d":"0.98"},1,"up","no"]
[99368,0,"chr19","-",12317477,12333688,"ENST00000293725",4,2754,"ENSG00000188868","ZNF563","GO:0000981(DNA-binding transcription factor activity, RNA polymerase II-specific);GO:0003676(nucleic acid binding);GO:0003677(DNA binding);GO:0005622(intracellular);GO:0005634(nucleus);GO:0006355(regulation of transcription, DNA-templated);GO:0006357(regulation of transcription by RNA polymerase II);GO:0046872(metal ion binding)","05168(Herpes simplex virus 1 infection)","K09228","NA","zinc finger protein 563 [Source:HGNC Symbol;Acc:HGNC:30498]",{"v":0.605253,"d":"0.61"},{"v":0.373233,"d":"0.37"},{"v":0.646948,"d":"0.65"},{"v":0.617247,"d":"0.62"},{"v":0.451349,"d":"0.45"},{"v":0.556442,"d":"0.56"},{"v":1.00024368660917,"d":"1.00"},{"v":0.000351522633647283,"d":"0.00"},{"v":0.981283971952918,"d":"0.98"},1,"up","no"]
[89563,0,"chr17","-",69135230,69141888,"ENST00000590645",4,1511,"ENSG00000154262","ABCA6","GO:0000166(nucleotide binding);GO:0005319(lipid transporter activity);GO:0005524(ATP binding);GO:0005654(nucleoplasm);GO:0005886(plasma membrane);GO:0006869(lipid transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016887(ATPase activity);GO:0042626(ATPase activity, coupled to transmembrane movement of substances);GO:0043231(intracellular membrane-bounded organelle);GO:0055085(transmembrane transport)","02010(ABC transporters)","K05649","NA","ATP binding cassette subfamily A member 6 [Source:HGNC Symbol;Acc:HGNC:36]",{"v":0.38199,"d":"0.38"},{"v":0.586803,"d":"0.59"},{"v":0.585866,"d":"0.59"},{"v":0.406849,"d":"0.41"},{"v":0.634557,"d":"0.63"},{"v":0.457005,"d":"0.46"},{"v":1.03753843237937,"d":"1.04"},{"v":0.0531647775932435,"d":"0.05"},{"v":0.984195131547977,"d":"0.98"},1,"up","no"]
[9719,0,"chr1","-",113894748,113905070,"ENST00000256658",11,2742,"ENSG00000134262","AP4B1","GO:0005515(protein binding);GO:0005794(Golgi apparatus);GO:0005802(trans-Golgi network);GO:0005829(cytosol);GO:0006605(protein targeting);GO:0006886(intracellular protein transport);GO:0008104(protein localization);GO:0015031(protein transport);GO:0016020(membrane);GO:0016192(vesicle-mediated transport);GO:0019898(extrinsic component of membrane);GO:0030117(membrane coat);GO:0030124(AP-4 adaptor complex);GO:0030131(clathrin adaptor complex);GO:0030276(clathrin binding);GO:0031904(endosome lumen);GO:0032588(trans-Golgi network membrane)","04142(Lysosome)","K12401","NA","adaptor related protein complex 4 subunit beta 1 [Source:HGNC Symbol;Acc:HGNC:572]",{"v":1.823024,"d":"1.82"},{"v":0.678444,"d":"0.68"},{"v":2.225029,"d":"2.23"},{"v":0.982262,"d":"0.98"},{"v":1.960365,"d":"1.96"},{"v":1.778935,"d":"1.78"},{"v":1.00104520495548,"d":"1.00"},{"v":0.00150712451610871,"d":"0.00"},{"v":0.985718906345329,"d":"0.99"},1,"up","no"]
[8144,0,"chr1","+",89821032,89936611,"ENST00000337338",3,3950,"ENSG00000171492","LRRC8D","GO:0005225(volume-sensitive anion channel activity);GO:0005515(protein binding);GO:0005623(cell);GO:0005737(cytoplasm);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005886(plasma membrane);GO:0005887(integral component of plasma membrane);GO:0006811(ion transport);GO:0006884(cell volume homeostasis);GO:0015698(inorganic anion transport);GO:0015734(taurine transport);GO:0015810(aspartate transmembrane transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0034702(ion channel complex);GO:0055085(transmembrane transport);GO:0071470(cellular response to osmotic stress);GO:0098656(anion transmembrane transport)","NA","K22038","NA","leucine rich repeat containing 8 VRAC subunit D [Source:HGNC Symbol;Acc:HGNC:16992]",{"v":1.109336,"d":"1.11"},{"v":1.274374,"d":"1.27"},{"v":2.114569,"d":"2.11"},{"v":0.996934,"d":"1.00"},{"v":2.522893,"d":"2.52"},{"v":0.949794,"d":"0.95"},{"v":1.00641172931665,"d":"1.01"},{"v":0.0092206414478348,"d":"0.01"},{"v":0.987083891100474,"d":"0.99"},1,"up","no"]
[207358,0,"chrX","+",154398379,154400817,"ENST00000485196",5,839,"ENSG00000147403","RPL10","GO:0000027(ribosomal large subunit assembly);GO:0000122(negative regulation of transcription by RNA polymerase II);GO:0000184(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay);GO:0003723(RNA binding);GO:0003735(structural constituent of ribosome);GO:0005515(protein binding);GO:0005622(intracellular);GO:0005634(nucleus);GO:0005783(endoplasmic reticulum);GO:0005790(smooth endoplasmic reticulum);GO:0005829(cytosol);GO:0005840(ribosome);GO:0006412(translation);GO:0006413(translational initiation);GO:0006417(regulation of translation);GO:0006614(SRP-dependent cotranslational protein targeting to membrane);GO:0007275(multicellular organism development);GO:0016020(membrane);GO:0019083(viral transcription);GO:0022625(cytosolic large ribosomal subunit);GO:0032991(protein-containing complex);GO:0043066(negative regulation of apoptotic process);GO:0045182(translation regulator activity);GO:1990403(embryonic brain development)","03010(Ribosome)","K02866","NA","ribosomal protein L10 [Source:HGNC Symbol;Acc:HGNC:10298]",{"v":24.456554,"d":"24.46"},{"v":15.642426,"d":"15.64"},{"v":15.296329,"d":"15.30"},{"v":16.619749,"d":"16.62"},{"v":17.164019,"d":"17.16"},{"v":20.396683,"d":"20.40"},{"v":1.02242244162936,"d":"1.02"},{"v":0.0319914081346977,"d":"0.03"},{"v":0.988752010804424,"d":"0.99"},1,"up","no"]
[93089,0,"chr18","+",11981507,12030877,"ENST00000269159",8,1449,"ENSG00000141401","IMPA2","GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0006021(inositol biosynthetic process);GO:0006796(phosphate-containing compound metabolic process);GO:0007165(signal transduction);GO:0008934(inositol monophosphate 1-phosphatase activity);GO:0016787(hydrolase activity);GO:0042803(protein homodimerization activity);GO:0043647(inositol phosphate metabolic process);GO:0046854(phosphatidylinositol phosphorylation);GO:0046855(inositol phosphate dephosphorylation);GO:0046872(metal ion binding);GO:0052832(inositol monophosphate 3-phosphatase activity);GO:0052833(inositol monophosphate 4-phosphatase activity);GO:0052834(inositol monophosphate phosphatase activity)","00562(Inositol phosphate metabolism);04070(Phosphatidylinositol signaling system)","K01092","EC:3.1.3.25","inositol monophosphatase 2 [Source:HGNC Symbol;Acc:HGNC:6051]",{"v":3.373194,"d":"3.37"},{"v":2.425904,"d":"2.43"},{"v":2.860185,"d":"2.86"},{"v":4.313506,"d":"4.31"},{"v":1.76413,"d":"1.76"},{"v":2.328118,"d":"2.33"},{"v":1.03016136327568,"d":"1.03"},{"v":0.0428703371794154,"d":"0.04"},{"v":0.990341345841409,"d":"0.99"},1,"up","no"]
[199033,0,"chr9","-",124878357,124941099,"ENST00000373555",23,4811,"ENSG00000136935","GOLGA1","GO:0000139(Golgi membrane);GO:0001669(acrosomal vesicle);GO:0005515(protein binding);GO:0005794(Golgi apparatus);GO:0005802(trans-Golgi network);GO:0005829(cytosol);GO:0016020(membrane);GO:0031410(cytoplasmic vesicle);GO:0048471(perinuclear region of cytoplasm)","NA","K16731","NA","golgin A1 [Source:HGNC Symbol;Acc:HGNC:4424]",{"v":5.010082,"d":"5.01"},{"v":5.071843,"d":"5.07"},{"v":5.02225,"d":"5.02"},{"v":4.948835,"d":"4.95"},{"v":4.921872,"d":"4.92"},{"v":5.031284,"d":"5.03"},{"v":1.01356758301626,"d":"1.01"},{"v":0.0194422885400885,"d":"0.02"},{"v":0.993507748633574,"d":"0.99"},1,"up","no"]
[99847,0,"chr19","-",13961530,14006320,"ENST00000254325",21,4375,"ENSG00000132005","RFX1","GO:0000978(RNA polymerase II proximal promoter sequence-specific DNA binding);GO:0000981(DNA-binding transcription factor activity, RNA polymerase II-specific);GO:0003677(DNA binding);GO:0003700(DNA-binding transcription factor activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0006355(regulation of transcription, DNA-templated);GO:0006357(regulation of transcription by RNA polymerase II);GO:0006955(immune response);GO:0043231(intracellular membrane-bounded organelle)","NA","K09173","NA","regulatory factor X1 [Source:HGNC Symbol;Acc:HGNC:9982]",{"v":1.956627,"d":"1.96"},{"v":2.059706,"d":"2.06"},{"v":2.082643,"d":"2.08"},{"v":1.92959,"d":"1.93"},{"v":1.989695,"d":"1.99"},{"v":2.102171,"d":"2.10"},{"v":1.01287396270935,"d":"1.01"},{"v":0.0184546630956519,"d":"0.02"},{"v":0.994995746906195,"d":"0.99"},1,"up","no"]
[140723,0,"chr3","-",52524401,52526290,"ENST00000462261",4,1619,"ENSG00000168268","NT5DC2","GO:0008253(5'-nucleotidase activity);GO:0016311(dephosphorylation);GO:0016787(hydrolase activity);GO:0046872(metal ion binding)","NA","NA","NA","5'-nucleotidase domain containing 2 [Source:HGNC Symbol;Acc:HGNC:25717]",{"v":1.693085,"d":"1.69"},{"v":1.38025,"d":"1.38"},{"v":1.324893,"d":"1.32"},{"v":1.957355,"d":"1.96"},{"v":1.855125,"d":"1.86"},{"v":0.476363,"d":"0.48"},{"v":1.02550454749684,"d":"1.03"},{"v":0.0363338893181028,"d":"0.04"},{"v":0.996243346709876,"d":"1.00"},1,"up","no"]
[181420,0,"chr7","+",95772554,96098424,"ENST00000447467",17,2947,"ENSG00000158560","DYNC1I1","GO:0000775(chromosome, centromeric region);GO:0000776(kinetochore);GO:0000777(condensed chromosome kinetochore);GO:0000922(spindle pole);GO:0003774(motor activity);GO:0003777(microtubule motor activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005694(chromosome);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005856(cytoskeleton);GO:0005868(cytoplasmic dynein complex);GO:0005874(microtubule);GO:0006888(endoplasmic reticulum to Golgi vesicle-mediated transport);GO:0007018(microtubule-based movement);GO:0008017(microtubule binding);GO:0008574(ATP-dependent microtubule motor activity, plus-end-directed);GO:0019886(antigen processing and presentation of exogenous peptide antigen via MHC class II);GO:0030286(dynein complex);GO:0030507(spectrin binding);GO:0031982(vesicle);GO:0036464(cytoplasmic ribonucleoprotein granule);GO:0045503(dynein light chain binding);GO:0045504(dynein heavy chain binding);GO:0047496(vesicle transport along microtubule);GO:0048471(perinuclear region of cytoplasm);GO:0055037(recycling endosome)","04145(Phagosome);04962(Vasopressin-regulated water reabsorption);05132(Salmonella infection)","K10415","NA","dynein cytoplasmic 1 intermediate chain 1 [Source:HGNC Symbol;Acc:HGNC:2963]",0,{"v":0.570658,"d":"0.57"},{"v":0.55981,"d":"0.56"},{"v":0.498355,"d":"0.50"},0,{"v":0.609254,"d":"0.61"},{"v":1.02063814938304,"d":"1.02"},{"v":0.0294714728561674,"d":"0.03"},{"v":0.997659293413536,"d":"1.00"},1,"up","no"]
[31443,0,"chr11","+",62771396,62787342,"ENST00000294168",11,2023,"ENSG00000162227","TAF6L","GO:0000118(histone deacetylase complex);GO:0000124(SAGA complex);GO:0003677(DNA binding);GO:0003713(transcription coactivator activity);GO:0004402(histone acetyltransferase activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005669(transcription factor TFIID complex);GO:0006325(chromatin organization);GO:0006338(chromatin remodeling);GO:0006352(DNA-templated transcription, initiation);GO:0006357(regulation of transcription by RNA polymerase II);GO:0006366(transcription by RNA polymerase II);GO:0006367(transcription initiation from RNA polymerase II promoter);GO:0030914(STAGA complex);GO:0043966(histone H3 acetylation);GO:0046695(SLIK (SAGA-like) complex);GO:0046982(protein heterodimerization activity);GO:0051123(RNA polymerase II preinitiation complex assembly);GO:0070062(extracellular exosome);GO:1903508(positive regulation of nucleic acid-templated transcription)","03022(Basal transcription factors)","K03131","NA","TATA-box binding protein associated factor 6 like [Source:HGNC Symbol;Acc:HGNC:17305]",{"v":5.156308,"d":"5.16"},{"v":5.018416,"d":"5.02"},{"v":4.469202,"d":"4.47"},{"v":4.83526,"d":"4.84"},{"v":4.468998,"d":"4.47"},{"v":5.104296,"d":"5.10"},{"v":1.01633557399306,"d":"1.02"},{"v":0.0233768302612499,"d":"0.02"},{"v":0.999873894558276,"d":"1.00"},1,"up","no"]
[34984,0,"chr11","-",86000681,86068797,"ENST00000534412",8,811,"ENSG00000073921","PICALM","GO:0000149(SNARE binding);GO:0001540(amyloid-beta binding);GO:0005515(protein binding);GO:0005543(phospholipid binding);GO:0005545(1-phosphatidylinositol binding);GO:0005546(phosphatidylinositol-4,5-bisphosphate binding);GO:0005634(nucleus);GO:0005769(early endosome);GO:0005794(Golgi apparatus);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0005905(clathrin-coated pit);GO:0006897(endocytosis);GO:0006898(receptor-mediated endocytosis);GO:0006900(vesicle budding from membrane);GO:0007409(axonogenesis);GO:0007611(learning or memory);GO:0008021(synaptic vesicle);GO:0009986(cell surface);GO:0010629(negative regulation of gene expression);GO:0016020(membrane);GO:0016185(synaptic vesicle budding from presynaptic endocytic zone membrane);GO:0016188(synaptic vesicle maturation);GO:0016192(vesicle-mediated transport);GO:0016197(endosomal transport);GO:0017137(Rab GTPase binding);GO:0030097(hemopoiesis);GO:0030100(regulation of endocytosis);GO:0030122(AP-2 adaptor complex);GO:0030132(clathrin coat of coated pit);GO:0030136(clathrin-coated vesicle);GO:0030276(clathrin binding);GO:0031224(intrinsic component of membrane);GO:0031410(cytoplasmic vesicle);GO:0031623(receptor internalization);GO:0031982(vesicle);GO:0032050(clathrin heavy chain binding);GO:0032880(regulation of protein localization);GO:0035459(vesicle cargo loading);GO:0042734(presynaptic membrane);GO:0043025(neuronal cell body);GO:0043231(intracellular membrane-bounded organelle);GO:0043547(positive regulation of GTPase activity);GO:0045211(postsynaptic membrane);GO:0045296(cadherin binding);GO:0045334(clathrin-coated endocytic vesicle);GO:0045893(positive regulation of transcription, DNA-templated);GO:0048156(tau protein binding);GO:0048261(negative regulation of receptor-mediated endocytosis);GO:0048268(clathrin coat assembly);GO:0048471(perinuclear region of cytoplasm);GO:0048488(synaptic vesicle endocytosis);GO:0048813(dendrite morphogenesis);GO:0050750(low-density lipoprotein particle receptor binding);GO:0055072(iron ion homeostasis);GO:0061024(membrane organization);GO:0065003(protein-containing complex assembly);GO:0070381(endosome to plasma membrane transport vesicle);GO:0072583(clathrin-dependent endocytosis);GO:0090647(modulation of age-related behavioral decline);GO:0097418(neurofibrillary tangle);GO:0097494(regulation of vesicle size);GO:0097753(membrane bending);GO:0098711(iron ion import across plasma membrane);GO:0098894(extrinsic component of presynaptic endocytic zone membrane);GO:0150093(amyloid-beta clearance by transcytosis);GO:1901216(positive regulation of neuron death);GO:1902004(positive regulation of amyloid-beta formation);GO:1902959(regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process);GO:1902961(positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process);GO:1902963(negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process);GO:1903077(negative regulation of protein localization to plasma membrane);GO:1905224(clathrin-coated pit assembly);GO:2000009(negative regulation of protein localization to cell surface)","NA","K20044","NA","phosphatidylinositol binding clathrin assembly protein [Source:HGNC Symbol;Acc:HGNC:15514]",{"v":0.184534,"d":"0.18"},0,0,{"v":0.358792,"d":"0.36"},{"v":0.851666,"d":"0.85"},{"v":0.531893,"d":"0.53"},{"v":0.105910921507779,"d":"0.11"},{"v":-3.23907672753364,"d":"-3.24"},1,1,"down","no"]
[170225,0,"chr6","-",36677609,36678559,"ENST00000643333",1,951,"ENSG00000285244","DINOL","NA","NA","NA","NA","damage induced long noncoding RNA [Source:HGNC Symbol;Acc:HGNC:53146]",{"v":0.068893,"d":"0.07"},0,{"v":0.092467,"d":"0.09"},{"v":0.008624,"d":"0.01"},0,0,{"v":18.7105751391466,"d":"18.71"},{"v":4.22578200074782,"d":"4.23"},1,1,"up","no"]
[196149,0,"chr9","-",61883640,61883751,"ENST00000459296",1,112,"ENSG00000238749","RF00019","NA","NA","NA","NA","NA",0,0,0,0,0,0,1,0,1,1,"no","no"]
[112873,0,"chr2","+",61888724,62136058,"ENST00000472729",3,629,"ENSG00000173163","COMMD1","GO:0005507(copper ion binding);GO:0005515(protein binding);GO:0005546(phosphatidylinositol-4,5-bisphosphate binding);GO:0005547(phosphatidylinositol-3,4,5-trisphosphate binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0005768(endosome);GO:0005769(early endosome);GO:0005829(cytosol);GO:0006893(Golgi to plasma membrane transport);GO:0008289(lipid binding);GO:0010008(endosome membrane);GO:0015031(protein transport);GO:0016020(membrane);GO:0016567(protein ubiquitination);GO:0031398(positive regulation of protein ubiquitination);GO:0031410(cytoplasmic vesicle);GO:0031462(Cul2-RING ubiquitin ligase complex);GO:0032088(negative regulation of NF-kappaB transcription factor activity);GO:0032434(regulation of proteasomal ubiquitin-dependent protein catabolic process);GO:0042802(identical protein binding);GO:0042803(protein homodimerization activity);GO:0043325(phosphatidylinositol-3,4-bisphosphate binding);GO:0043687(post-translational protein modification);GO:0046872(metal ion binding);GO:0048227(plasma membrane to endosome transport);GO:0055037(recycling endosome);GO:0055070(copper ion homeostasis);GO:0070300(phosphatidic acid binding);GO:0080025(phosphatidylinositol-3,5-bisphosphate binding);GO:1902306(negative regulation of sodium ion transmembrane transport);GO:2000009(negative regulation of protein localization to cell surface)","NA","K22557","NA","copper metabolism domain containing 1 [Source:HGNC Symbol;Acc:HGNC:23024]",0,0,{"v":0.039582,"d":"0.04"},0,0,0,"inf","inf",1,1,"up","no"]
[179236,0,"chr7","-",56083151,56087693,"ENST00000471665",3,453,"ENSG00000164776","PHKG1","GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0004683(calmodulin-dependent protein kinase activity);GO:0004689(phosphorylase kinase activity);GO:0005516(calmodulin binding);GO:0005524(ATP binding);GO:0005829(cytosol);GO:0005964(phosphorylase kinase complex);GO:0005975(carbohydrate metabolic process);GO:0005977(glycogen metabolic process);GO:0005978(glycogen biosynthetic process);GO:0005980(glycogen catabolic process);GO:0006468(protein phosphorylation);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0016740(transferase activity);GO:0019899(enzyme binding);GO:0050321(tau-protein kinase activity)","04020(Calcium signaling pathway);04910(Insulin signaling pathway);04922(Glucagon signaling pathway)","K00871","EC:2.7.11.19","phosphorylase kinase catalytic subunit gamma 1 [Source:HGNC Symbol;Acc:HGNC:8930]",{"v":0.020684,"d":"0.02"},{"v":0.166961,"d":"0.17"},{"v":0.064363,"d":"0.06"},0,{"v":0.091622,"d":"0.09"},0,{"v":2.75051843443714,"d":"2.75"},{"v":1.45970357220045,"d":"1.46"},1,1,"up","no"]
[15552,0,"chr1","+",203795654,203818665,"ENST00000432282",6,682,"ENSG00000058673","ZC3H11A","GO:0000346(transcription export complex);GO:0003723(RNA binding);GO:0003729(mRNA binding);GO:0005515(protein binding);GO:0005654(nucleoplasm);GO:0006405(RNA export from nucleus);GO:0006406(mRNA export from nucleus);GO:0016973(poly(A)+ mRNA export from nucleus);GO:0031124(mRNA 3'-end processing);GO:0046872(metal ion binding);GO:0051028(mRNA transport)","NA","K22415","NA","zinc finger CCCH-type containing 11A [Source:HGNC Symbol;Acc:HGNC:29093]",0,0,0,{"v":0.064457,"d":"0.06"},0,0,"-inf","-inf",1,1,"down","no"]
[78919,0,"chr16","-",89291707,89490320,"ENST00000647213",4,371,"ENSG00000167522","ANKRD11","GO:0001701(in utero embryonic development);GO:0001894(tissue homeostasis);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0035264(multicellular organism growth);GO:0042475(odontogenesis of dentin-containing tooth);GO:0048705(skeletal system morphogenesis);GO:0060323(head morphogenesis);GO:0060325(face morphogenesis);GO:0060348(bone development)","NA","K21436","NA","ankyrin repeat domain 11 [Source:HGNC Symbol;Acc:HGNC:21316]",0,0,0,0,0,0,1,0,1,1,"no","no"]
[23758,0,"chr10","+",101036062,101037600,"ENST00000465383",5,549,"ENSG00000107819","SFXN3","GO:0005739(mitochondrion);GO:0006730(one-carbon metabolic process);GO:0006811(ion transport);GO:0006865(amino acid transport);GO:0015075(ion transmembrane transporter activity);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0022889(serine transmembrane transporter activity);GO:0031966(mitochondrial membrane);GO:0034220(ion transmembrane transport);GO:0055085(transmembrane transport);GO:0140300(serine import into mitochondrion);GO:1990542(mitochondrial transmembrane transport)","NA","NA","NA","sideroflexin 3 [Source:HGNC Symbol;Acc:HGNC:16087]",{"v":0.908649,"d":"0.91"},{"v":0.904277,"d":"0.90"},{"v":1.230213,"d":"1.23"},{"v":0.825346,"d":"0.83"},{"v":0.70678,"d":"0.71"},{"v":2.093402,"d":"2.09"},{"v":0.839364362928655,"d":"0.84"},{"v":-0.252630883173573,"d":"-0.25"},1,1,"down","no"]
[44500,0,"chr12","-",56746033,56752269,"ENST00000546761",3,381,"ENSG00000198056","PRIM1","GO:0000082(G1/S transition of mitotic cell cycle);GO:0003697(single-stranded DNA binding);GO:0003896(DNA primase activity);GO:0003899(DNA-directed 5'-3' RNA polymerase activity);GO:0005654(nucleoplasm);GO:0005658(alpha DNA polymerase:primase complex);GO:0006260(DNA replication);GO:0006269(DNA replication, synthesis of RNA primer);GO:0006270(DNA replication initiation);GO:0016020(membrane);GO:0016740(transferase activity);GO:0016779(nucleotidyltransferase activity);GO:0032201(telomere maintenance via semi-conservative replication);GO:0046872(metal ion binding)","03030(DNA replication)","NA","NA","DNA primase subunit 1 [Source:HGNC Symbol;Acc:HGNC:9369]",0,0,{"v":0.000413,"d":"0.00"},{"v":0.060326,"d":"0.06"},0,0,{"v":0.00684613599443026,"d":"0.01"},{"v":-7.19049433374854,"d":"-7.19"},1,1,"down","no"]
[163459,0,"chr5","+",140459257,140524133,"ENST00000246149",17,2062,"ENSG00000131503","ANKHD1","GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0045087(innate immune response)","NA","K16726","NA","ankyrin repeat and KH domain containing 1 [Source:HGNC Symbol;Acc:HGNC:24714]",{"v":0.239989,"d":"0.24"},0,{"v":0.183699,"d":"0.18"},0,{"v":0.38062,"d":"0.38"},{"v":0.249513,"d":"0.25"},{"v":0.672378688308659,"d":"0.67"},{"v":-0.572654097200064,"d":"-0.57"},1,1,"down","no"]
[78572,0,"chr16","-",87343686,87383748,"ENST00000636077",5,660,"ENSG00000103264","FBXO31","GO:0000209(protein polyubiquitination);GO:0005515(protein binding);GO:0005813(centrosome);GO:0005829(cytosol);GO:0006974(cellular response to DNA damage stimulus);GO:0007049(cell cycle);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016567(protein ubiquitination);GO:0019005(SCF ubiquitin ligase complex);GO:0030332(cyclin binding);GO:0031145(anaphase-promoting complex-dependent catabolic process);GO:0031146(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process);GO:0031571(mitotic G1 DNA damage checkpoint);GO:0043025(neuronal cell body);GO:0043687(post-translational protein modification);GO:0050775(positive regulation of dendrite morphogenesis);GO:2001224(positive regulation of neuron migration)","NA","K10308","NA","F-box protein 31 [Source:HGNC Symbol;Acc:HGNC:16510]",{"v":0.219615,"d":"0.22"},{"v":0.804823,"d":"0.80"},{"v":0.76584,"d":"0.77"},{"v":0.73235,"d":"0.73"},{"v":1.331413,"d":"1.33"},{"v":0.359634,"d":"0.36"},{"v":0.73874730388789,"d":"0.74"},{"v":-0.43684713480825,"d":"-0.44"},1,1,"down","no"]
[23735,0,"chr10","+",100987795,100989884,"ENST00000459764",2,327,"ENSG00000107815","TWNK","GO:0000166(nucleotide binding);GO:0002020(protease binding);GO:0003678(DNA helicase activity);GO:0003697(single-stranded DNA binding);GO:0004386(helicase activity);GO:0005524(ATP binding);GO:0005739(mitochondrion);GO:0005759(mitochondrial matrix);GO:0006260(DNA replication);GO:0006264(mitochondrial DNA replication);GO:0006268(DNA unwinding involved in DNA replication);GO:0006390(mitochondrial transcription);GO:0007005(mitochondrion organization);GO:0016787(hydrolase activity);GO:0032508(DNA duplex unwinding);GO:0034214(protein hexamerization);GO:0042645(mitochondrial nucleoid);GO:0043139(5'-3' DNA helicase activity);GO:0051260(protein homooligomerization);GO:0071333(cellular response to glucose stimulus)","NA","K17680","EC:3.6.4.12","twinkle mtDNA helicase [Source:HGNC Symbol;Acc:HGNC:1160]",{"v":0.114763,"d":"0.11"},0,0,{"v":0.109745,"d":"0.11"},{"v":0.126333,"d":"0.13"},0,{"v":0.48612323045773,"d":"0.49"},{"v":-1.04060601678767,"d":"-1.04"},1,1,"down","no"]
[184440,0,"chr7","+",139778400,140020293,"ENST00000336425",17,2185,"ENSG00000059377","TBXAS1","GO:0001516(prostaglandin biosynthetic process);GO:0004497(monooxygenase activity);GO:0004796(thromboxane-A synthase activity);GO:0005506(iron ion binding);GO:0005623(cell);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0006629(lipid metabolic process);GO:0006631(fatty acid metabolic process);GO:0006633(fatty acid biosynthetic process);GO:0006690(icosanoid metabolic process);GO:0006693(prostaglandin metabolic process);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016491(oxidoreductase activity);GO:0016705(oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen);GO:0016853(isomerase activity);GO:0019371(cyclooxygenase pathway);GO:0020037(heme binding);GO:0030644(cellular chloride ion homeostasis);GO:0036134(12-hydroxyheptadecatrienoic acid synthase activity);GO:0045471(response to ethanol);GO:0045907(positive regulation of vasoconstriction);GO:0046872(metal ion binding);GO:0055114(oxidation-reduction process);GO:0070542(response to fatty acid)","00590(Arachidonic acid metabolism);04611(Platelet activation)","K01832","EC:5.3.99.5","thromboxane A synthase 1 [Source:HGNC Symbol;Acc:HGNC:11609]",0,0,{"v":0.502259,"d":"0.50"},0,0,0,"inf","inf",1,1,"up","no"]
[116533,0,"chr2","+",113424495,113425324,"ENST00000422178",2,508,"ENSG00000234997","AC016745","NA","NA","NA","NA","novel transcript",0,0,0,0,0,0,1,0,1,1,"no","no"]
[40202,0,"chr12","-",11030387,11031407,"ENST00000390675",1,1021,"ENSG00000256436","TAS2R31","GO:0001580(detection of chemical stimulus involved in sensory perception of bitter taste);GO:0004930(G protein-coupled receptor activity);GO:0005886(plasma membrane);GO:0007165(signal transduction);GO:0007186(G protein-coupled receptor signaling pathway);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0033038(bitter taste receptor activity);GO:0050896(response to stimulus);GO:0050909(sensory perception of taste)","04742(Taste transduction)","K08474","NA","taste 2 receptor member 31 [Source:HGNC Symbol;Acc:HGNC:19113]",0,{"v":0.043103,"d":"0.04"},0,{"v":0.102813,"d":"0.10"},{"v":0.025405,"d":"0.03"},{"v":0.021715,"d":"0.02"},{"v":0.287481741844691,"d":"0.29"},{"v":-1.79845776243581,"d":"-1.80"},1,1,"down","no"]
[135077,0,"chr22","-",41576931,41589871,"ENST00000472620",8,1576,"ENSG00000100417","PMM1","GO:0004615(phosphomannomutase activity);GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0006013(mannose metabolic process);GO:0006487(protein N-linked glycosylation);GO:0009298(GDP-mannose biosynthetic process);GO:0016853(isomerase activity);GO:0043025(neuronal cell body);GO:0045047(protein targeting to ER);GO:0046872(metal ion binding);GO:1990830(cellular response to leukemia inhibitory factor)","00051(Fructose and mannose metabolism);00520(Amino sugar and nucleotide sugar metabolism)","K17497","EC:5.4.2.8","phosphomannomutase 1 [Source:HGNC Symbol;Acc:HGNC:9114]",{"v":0.104356,"d":"0.10"},{"v":0.13589,"d":"0.14"},{"v":0.033141,"d":"0.03"},0,{"v":0.110289,"d":"0.11"},{"v":0.013681,"d":"0.01"},{"v":2.20526740340405,"d":"2.21"},{"v":1.1409536028008,"d":"1.14"},1,1,"up","no"]
[140105,0,"chr3","-",49809184,49809887,"ENST00000478875",2,615,"ENSG00000182179","UBA7","GO:0000166(nucleotide binding);GO:0004842(ubiquitin-protein transferase activity);GO:0005515(protein binding);GO:0005524(ATP binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0006464(cellular protein modification process);GO:0006974(cellular response to DNA damage stimulus);GO:0008641(ubiquitin-like modifier activating enzyme activity);GO:0016567(protein ubiquitination);GO:0016874(ligase activity);GO:0019782(ISG15 activating enzyme activity);GO:0019941(modification-dependent protein catabolic process);GO:0032020(ISG15-protein conjugation);GO:0032446(protein modification by small protein conjugation);GO:0032480(negative regulation of type I interferon production)","04120(Ubiquitin mediated proteolysis);05012(Parkinson disease)","K10698","EC:6.2.1.45","ubiquitin like modifier activating enzyme 7 [Source:HGNC Symbol;Acc:HGNC:12471]",{"v":0.153734,"d":"0.15"},{"v":0.221894,"d":"0.22"},{"v":0.155793,"d":"0.16"},{"v":0.326988,"d":"0.33"},{"v":0.051187,"d":"0.05"},{"v":0.0213,"d":"0.02"},{"v":1.3302985168033,"d":"1.33"},{"v":0.411750020453878,"d":"0.41"},1,1,"up","no"]
[89104,0,"chr17","-",64147227,64263227,"ENST00000258991",12,5232,"ENSG00000136478","TEX2","GO:0003674(molecular_function);GO:0005783(endoplasmic reticulum);GO:0006665(sphingolipid metabolic process);GO:0006869(lipid transport);GO:0007165(signal transduction);GO:0008289(lipid binding);GO:0016020(membrane);GO:0016021(integral component of membrane)","NA","NA","NA","testis expressed 2 [Source:HGNC Symbol;Acc:HGNC:30884]",{"v":0.008175,"d":"0.01"},0,{"v":0.000645,"d":"0.00"},0,{"v":1.125731,"d":"1.13"},{"v":0.008042,"d":"0.01"},{"v":0.00777933501679789,"d":"0.01"},{"v":-7.00613744679902,"d":"-7.01"},1,1,"down","no"]
[88539,0,"chr17","-",60085109,60088286,"ENST00000645235",2,185,"ENSG00000261040","WFDC21P","NA","NA","NA","NA","WAP four-disulfide core domain 21, pseudogene [Source:HGNC Symbol;Acc:HGNC:50357]",{"v":0.109808,"d":"0.11"},{"v":0.169554,"d":"0.17"},0,{"v":0.019041,"d":"0.02"},{"v":0.048381,"d":"0.05"},{"v":0.028538,"d":"0.03"},{"v":2.91123384743643,"d":"2.91"},{"v":1.54163072987178,"d":"1.54"},1,1,"up","no"]
[36698,0,"chr11","+",117234263,117286445,"ENST00000530849",13,2846,"ENSG00000167257","RNF214","GO:0004842(ubiquitin-protein transferase activity);GO:0016567(protein ubiquitination);GO:0046872(metal ion binding)","NA","NA","NA","ring finger protein 214 [Source:HGNC Symbol;Acc:HGNC:25335]",{"v":0.017141,"d":"0.02"},{"v":0.015252,"d":"0.02"},{"v":0.067373,"d":"0.07"},{"v":1.632954,"d":"1.63"},0,{"v":0.047002,"d":"0.05"},{"v":0.0593860791592161,"d":"0.06"},{"v":-4.07373140490517,"d":"-4.07"},1,1,"down","no"]
[160529,0,"chr5","-",81330453,81335902,"ENST00000506440",3,752,"ENSG00000172497","ACOT12","GO:0000062(fatty-acyl-CoA binding);GO:0003986(acetyl-CoA hydrolase activity);GO:0005524(ATP binding);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0006084(acetyl-CoA metabolic process);GO:0006090(pyruvate metabolic process);GO:0006629(lipid metabolic process);GO:0006631(fatty acid metabolic process);GO:0006637(acyl-CoA metabolic process);GO:0008289(lipid binding);GO:0016290(palmitoyl-CoA hydrolase activity);GO:0016787(hydrolase activity);GO:0016790(thiolester hydrolase activity);GO:0036042(long-chain fatty acyl-CoA binding);GO:0047617(acyl-CoA hydrolase activity);GO:0052689(carboxylic ester hydrolase activity);GO:1900535(palmitic acid biosynthetic process)","00620(Pyruvate metabolism)","K01067","EC:3.1.2.1","acyl-CoA thioesterase 12 [Source:HGNC Symbol;Acc:HGNC:24436]",{"v":0.063058,"d":"0.06"},0,{"v":0.046485,"d":"0.05"},{"v":0.201993,"d":"0.20"},0,0,{"v":0.542310872158936,"d":"0.54"},{"v":-0.882808001332041,"d":"-0.88"},1,1,"down","no"]
[156424,0,"chr4","-",174135055,174154637,"ENST00000511346",2,1144,"ENSG00000250957","AC012055","NA","NA","NA","NA","novel transcript",0,0,0,0,0,0,1,0,1,1,"no","no"]
[70506,0,"chr16","+",3032481,3039133,"ENST00000382225",8,3061,"ENSG00000205890","AC108134","NA","NA","NA","NA","novel transcript, antisense to CCDC64B",{"v":0.008632,"d":"0.01"},0,0,0,0,0,"inf","inf",1,1,"up","no"]
[192363,0,"chr8","+",124483345,124486234,"ENST00000517684",2,467,"ENSG00000170881","RNF139","GO:0002020(protease binding);GO:0004842(ubiquitin-protein transferase activity);GO:0005515(protein binding);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0008270(zinc ion binding);GO:0008285(negative regulation of cell population proliferation);GO:0012505(endomembrane system);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016567(protein ubiquitination);GO:0016740(transferase activity);GO:0017148(negative regulation of translation);GO:0019787(ubiquitin-like protein transferase activity);GO:0031648(protein destabilization);GO:0036503(ERAD pathway);GO:0036513(Derlin-1 retrotranslocation complex);GO:0038023(signaling receptor activity);GO:0044322(endoplasmic reticulum quality control compartment);GO:0046872(metal ion binding);GO:0060628(regulation of ER to Golgi vesicle-mediated transport);GO:0061630(ubiquitin protein ligase activity);GO:0070613(regulation of protein processing);GO:1904380(endoplasmic reticulum mannose trimming);GO:2000060(positive regulation of ubiquitin-dependent protein catabolic process)","NA","K15703","EC:2.3.2.27","ring finger protein 139 [Source:HGNC Symbol;Acc:HGNC:17023]",0,0,{"v":0.163188,"d":"0.16"},{"v":0.020115,"d":"0.02"},{"v":0.016545,"d":"0.02"},{"v":0.244376,"d":"0.24"},{"v":0.580665822172248,"d":"0.58"},{"v":-0.784219974974038,"d":"-0.78"},1,1,"down","no"]
[99316,0,"chr19","-",12043805,12052939,"ENST00000547628",4,1734,"ENSG00000257446","ZNF878","GO:0000981(DNA-binding transcription factor activity, RNA polymerase II-specific);GO:0003676(nucleic acid binding);GO:0005622(intracellular);GO:0005634(nucleus);GO:0006355(regulation of transcription, DNA-templated);GO:0006357(regulation of transcription by RNA polymerase II);GO:0046872(metal ion binding)","05168(Herpes simplex virus 1 infection)","K09228","NA","zinc finger protein 878 [Source:HGNC Symbol;Acc:HGNC:37246]",{"v":0.006842,"d":"0.01"},{"v":0.091382,"d":"0.09"},{"v":0.075313,"d":"0.08"},{"v":0.044492,"d":"0.04"},{"v":0.03634,"d":"0.04"},0,{"v":2.14688489707047,"d":"2.15"},{"v":1.1022448447239,"d":"1.10"},1,1,"up","no"]
[113772,0,"chr2","-",72973181,73071728,"ENST00000416579",11,895,"ENSG00000144040","SFXN5","GO:0005739(mitochondrion);GO:0006811(ion transport);GO:0006865(amino acid transport);GO:0015075(ion transmembrane transporter activity);GO:0015137(citrate transmembrane transporter activity);GO:0015746(citrate transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0031966(mitochondrial membrane);GO:0034220(ion transmembrane transport);GO:0055085(transmembrane transport)","NA","NA","NA","sideroflexin 5 [Source:HGNC Symbol;Acc:HGNC:16073]",{"v":0.105016,"d":"0.11"},0,{"v":0.007839,"d":"0.01"},0,0,{"v":0.030402,"d":"0.03"},{"v":3.71209130978225,"d":"3.71"},{"v":1.89223219822137,"d":"1.89"},1,1,"up","no"]
[168192,0,"chr6","-",27890382,27890792,"ENST00000359303",1,411,"ENSG00000197153","HIST1H3J","GO:0000183(chromatin silencing at rDNA);GO:0000228(nuclear chromosome);GO:0000786(nucleosome);GO:0000788(nuclear nucleosome);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005694(chromosome);GO:0006325(chromatin organization);GO:0006334(nucleosome assembly);GO:0006335(DNA replication-dependent nucleosome assembly);GO:0007596(blood coagulation);GO:0016020(membrane);GO:0031492(nucleosomal DNA binding);GO:0032200(telomere organization);GO:0032991(protein-containing complex);GO:0038111(interleukin-7-mediated signaling pathway);GO:0044267(cellular protein metabolic process);GO:0045296(cadherin binding);GO:0045652(regulation of megakaryocyte differentiation);GO:0045814(negative regulation of gene expression, epigenetic);GO:0046982(protein heterodimerization activity);GO:0051290(protein heterotetramerization);GO:0060964(regulation of gene silencing by miRNA);GO:0060968(regulation of gene silencing);GO:0070062(extracellular exosome)","05034(Alcoholism);05202(Transcriptional misregulation in cancer);05322(Systemic lupus erythematosus)","K11253","NA","histone cluster 1 H3 family member j [Source:HGNC Symbol;Acc:HGNC:4774]",0,{"v":0.057715,"d":"0.06"},0,0,0,0,"inf","inf",1,1,"up","no"]
[90088,0,"chr17","+",75087727,75106162,"ENST00000580123",7,2019,"ENSG00000170190","SLC16A5","GO:0005886(plasma membrane);GO:0005887(integral component of plasma membrane);GO:0008028(monocarboxylic acid transmembrane transporter activity);GO:0015293(symporter activity);GO:0015718(monocarboxylic acid transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0055085(transmembrane transport)","NA","K08182","NA","solute carrier family 16 member 5 [Source:HGNC Symbol;Acc:HGNC:10926]",{"v":0.098534,"d":"0.10"},{"v":0.098512,"d":"0.10"},{"v":0.2667,"d":"0.27"},0,{"v":0.40143,"d":"0.40"},{"v":0.044282,"d":"0.04"},{"v":1.04046110492874,"d":"1.04"},{"v":0.0572230344867598,"d":"0.06"},1,1,"up","no"]
[122954,0,"chr2","-",230725143,230725403,"ENST00000412556",1,261,"ENSG00000237758","BANF1P3","NA","NA","NA","NA","barrier to autointegration factor 1 pseudogene 3 [Source:HGNC Symbol;Acc:HGNC:43883]",{"v":0.95275,"d":"0.95"},{"v":0.649341,"d":"0.65"},{"v":0.34409,"d":"0.34"},{"v":0.744397,"d":"0.74"},{"v":0.766146,"d":"0.77"},{"v":0.245199,"d":"0.25"},{"v":1.10846639198698,"d":"1.11"},{"v":0.148565029250102,"d":"0.15"},1,1,"up","no"]
[43760,0,"chr12","-",54402081,54403172,"ENST00000551564",3,354,"ENSG00000161638","ITGA5","GO:0001525(angiogenesis);GO:0001618(virus receptor activity);GO:0001726(ruffle);GO:0005154(epidermal growth factor receptor binding);GO:0005161(platelet-derived growth factor receptor binding);GO:0005178(integrin binding);GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0005783(endoplasmic reticulum);GO:0005794(Golgi apparatus);GO:0005886(plasma membrane);GO:0005911(cell-cell junction);GO:0005925(focal adhesion);GO:0007044(cell-substrate junction assembly);GO:0007155(cell adhesion);GO:0007157(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules);GO:0007159(leukocyte cell-cell adhesion);GO:0007229(integrin-mediated signaling pathway);GO:0007565(female pregnancy);GO:0007613(memory);GO:0008305(integrin complex);GO:0009897(external side of plasma membrane);GO:0009986(cell surface);GO:0010811(positive regulation of cell-substrate adhesion);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016032(viral process);GO:0030054(cell junction);GO:0030198(extracellular matrix organization);GO:0030335(positive regulation of cell migration);GO:0030949(positive regulation of vascular endothelial growth factor receptor signaling pathway);GO:0031410(cytoplasmic vesicle);GO:0031589(cell-substrate adhesion);GO:0032587(ruffle membrane);GO:0033627(cell adhesion mediated by integrin);GO:0033631(cell-cell adhesion mediated by integrin);GO:0034113(heterotypic cell-cell adhesion);GO:0035313(wound healing, spreading of epidermal cells);GO:0035987(endodermal cell differentiation);GO:0043184(vascular endothelial growth factor receptor 2 binding);GO:0045202(synapse);GO:0045765(regulation of angiogenesis);GO:0046718(viral entry into host cell);GO:0046872(metal ion binding);GO:0050731(positive regulation of peptidyl-tyrosine phosphorylation);GO:0050839(cell adhesion molecule binding);GO:0050900(leukocyte migration);GO:0071062(alphav-beta3 integrin-vitronectin complex);GO:1903672(positive regulation of sprouting angiogenesis);GO:2000811(negative regulation of anoikis)","04145(Phagosome);04151(PI3K-Akt signaling pathway);04510(Focal adhesion);04512(ECM-receptor interaction);04640(Hematopoietic cell lineage);04810(Regulation of actin cytoskeleton);05100(Bacterial invasion of epithelial cells);05131(Shigellosis);05133(Pertussis);05165(Human papillomavirus infection);05168(Herpes simplex virus 1 infection);05205(Proteoglycans in cancer);05206(MicroRNAs in cancer);05410(Hypertrophic cardiomyopathy (HCM));05412(Arrhythmogenic right ventricular cardiomyopathy (ARVC));05414(Dilated cardiomyopathy (DCM))","K06484","NA","integrin subunit alpha 5 [Source:HGNC Symbol;Acc:HGNC:6141]",{"v":0.157347,"d":"0.16"},{"v":0.211412,"d":"0.21"},{"v":0.212917,"d":"0.21"},{"v":0.126767,"d":"0.13"},{"v":0.167755,"d":"0.17"},{"v":0.499372,"d":"0.50"},{"v":0.732687235323608,"d":"0.73"},{"v":-0.448730613229043,"d":"-0.45"},1,1,"down","no"]
[126851,0,"chr20","+",38955910,38956547,"ENST00000620080",1,638,"ENSG00000274825","AL023803","NA","NA","NA","NA","novel transcript",0,0,0,0,0,0,1,0,1,1,"no","no"]
[52356,0,"chr13","+",72727925,72745045,"ENST00000471712",7,567,"ENSG00000136122","BORA","GO:0000086(G2/M transition of mitotic cell cycle);GO:0005515(protein binding);GO:0005829(cytosol);GO:0007049(cell cycle);GO:0007088(regulation of mitotic nuclear division);GO:0019901(protein kinase binding);GO:0032880(regulation of protein localization);GO:0051301(cell division);GO:0060236(regulation of mitotic spindle organization);GO:0072687(meiotic spindle)","NA","K16831","NA","bora, aurora kinase A activator [Source:HGNC Symbol;Acc:HGNC:24724]",{"v":0.002035,"d":"0.00"},0,0,{"v":0.000143,"d":"0.00"},{"v":0.004662,"d":"0.00"},0,{"v":0.423517169614984,"d":"0.42"},{"v":-1.2395076365075,"d":"-1.24"},1,1,"down","no"]
[152267,0,"chr4","-",75940950,75957371,"ENST00000502543",4,650,"ENSG00000198301","SDAD1","GO:0000055(ribosomal large subunit export from nucleus);GO:0003674(molecular_function);GO:0005634(nucleus);GO:0005730(nucleolus);GO:0015031(protein transport);GO:0030036(actin cytoskeleton organization);GO:0042254(ribosome biogenesis);GO:0042273(ribosomal large subunit biogenesis)","NA","K14856","NA","SDA1 domain containing 1 [Source:HGNC Symbol;Acc:HGNC:25537]",{"v":0.011062,"d":"0.01"},0,{"v":0.034207,"d":"0.03"},0,0,0,"inf","inf",1,1,"up","no"]
[67306,0,"chr15","+",80152789,80163131,"ENST00000537726",6,1396,"ENSG00000103876","FAH","GO:0003824(catalytic activity);GO:0004334(fumarylacetoacetase activity);GO:0005515(protein binding);GO:0005829(cytosol);GO:0006527(arginine catabolic process);GO:0006559(L-phenylalanine catabolic process);GO:0006572(tyrosine catabolic process);GO:0009072(aromatic amino acid family metabolic process);GO:0016787(hydrolase activity);GO:0046872(metal ion binding);GO:0070062(extracellular exosome);GO:1902000(homogentisate catabolic process)","00350(Tyrosine metabolism)","K01555","EC:3.7.1.2","fumarylacetoacetate hydrolase [Source:HGNC Symbol;Acc:HGNC:3579]",{"v":0.00827,"d":"0.01"},{"v":0.002917,"d":"0.00"},{"v":0.001138,"d":"0.00"},{"v":0.031829,"d":"0.03"},0,{"v":0.003331,"d":"0.00"},{"v":0.350540386803185,"d":"0.35"},{"v":-1.51234742387813,"d":"-1.51"},1,1,"down","no"]
[65207,0,"chr15","-",63734643,63749449,"ENST00000560519",4,591,"ENSG00000103657","HERC1","GO:0004842(ubiquitin-protein transferase activity);GO:0005085(guanyl-nucleotide exchange factor activity);GO:0005086(ARF guanyl-nucleotide exchange factor activity);GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0005794(Golgi apparatus);GO:0005829(cytosol);GO:0010507(negative regulation of autophagy);GO:0016020(membrane);GO:0016567(protein ubiquitination);GO:0016740(transferase activity);GO:0021702(cerebellar Purkinje cell differentiation);GO:0031175(neuron projection development);GO:0050885(neuromuscular process controlling balance)","04120(Ubiquitin mediated proteolysis)","K10594","EC:2.3.2.26","HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 [Source:HGNC Symbol;Acc:HGNC:4867]",{"v":0.00026,"d":"0.00"},{"v":0.106989,"d":"0.11"},{"v":0.001502,"d":"0.00"},{"v":0.041757,"d":"0.04"},{"v":0.000869,"d":"0.00"},{"v":0.00074,"d":"0.00"},{"v":2.50774800534981,"d":"2.51"},{"v":1.32639238414572,"d":"1.33"},1,1,"up","no"]
[178517,0,"chr7","+",44039523,44042306,"ENST00000441052",2,2590,"ENSG00000235314","LINC00957","NA","NA","NA","NA","long intergenic non-protein coding RNA 957 [Source:HGNC Symbol;Acc:HGNC:22332]",{"v":0.20496,"d":"0.20"},{"v":0.069352,"d":"0.07"},{"v":0.156969,"d":"0.16"},{"v":0.12076,"d":"0.12"},{"v":0.320066,"d":"0.32"},{"v":0.196355,"d":"0.20"},{"v":0.676857910075787,"d":"0.68"},{"v":-0.563075088183271,"d":"-0.56"},1,1,"down","no"]
[50709,0,"chr13","+",27660868,27665737,"ENST00000636679",2,100,"ENSG00000186184","POLR1D","GO:0003677(DNA binding);GO:0003899(DNA-directed 5'-3' RNA polymerase activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005736(RNA polymerase I complex);GO:0005829(cytosol);GO:0006351(transcription, DNA-templated);GO:0006361(transcription initiation from RNA polymerase I promoter);GO:0006362(transcription elongation from RNA polymerase I promoter);GO:0006363(termination of RNA polymerase I transcription);GO:0032481(positive regulation of type I interferon production);GO:0045815(positive regulation of gene expression, epigenetic);GO:0046983(protein dimerization activity)","03020(RNA polymerase);04623(Cytosolic DNA-sensing pathway)","K03020","NA","RNA polymerase I and III subunit D [Source:HGNC Symbol;Acc:HGNC:20422]",0,{"v":0.073347,"d":"0.07"},0,0,0,0,"inf","inf",1,1,"up","no"]
[157417,0,"chr5","+",6779458,6779998,"ENST00000606566",1,541,"ENSG00000272071","AC122710","NA","NA","NA","NA","novel transcript",{"v":0.077617,"d":"0.08"},0,0,0,0,0,"inf","inf",1,1,"up","no"]
[36761,0,"chr11","-",117837984,117876719,"ENST00000529335",8,708,"ENSG00000137726","FXYD6","GO:0003674(molecular_function);GO:0005515(protein binding);GO:0005886(plasma membrane);GO:0006811(ion transport);GO:0008150(biological_process);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0017080(sodium channel regulator activity);GO:0034220(ion transmembrane transport);GO:0043269(regulation of ion transport);GO:0098978(glutamatergic synapse);GO:0099055(integral component of postsynaptic membrane);GO:0099056(integral component of presynaptic membrane);GO:0099106(ion channel regulator activity);GO:1903779(regulation of cardiac conduction);GO:2000649(regulation of sodium ion transmembrane transporter activity)","NA","K13363","NA","FXYD domain containing ion transport regulator 6 [Source:HGNC Symbol;Acc:HGNC:4030]",0,0,0,{"v":0.274606,"d":"0.27"},{"v":0.14449,"d":"0.14"},{"v":0.272499,"d":"0.27"},"-inf","-inf",1,1,"down","no"]
[41565,0,"chr12","+",32731486,32738296,"ENST00000547078",7,450,"ENSG00000087470","DNM1L","GO:0000139(Golgi membrane);GO:0000166(nucleotide binding);GO:0000266(mitochondrial fission);GO:0001836(release of cytochrome c from mitochondria);GO:0003374(dynamin family protein polymerization involved in mitochondrial fission);GO:0003924(GTPase activity);GO:0005096(GTPase activator activity);GO:0005515(protein binding);GO:0005525(GTP binding);GO:0005737(cytoplasm);GO:0005739(mitochondrion);GO:0005741(mitochondrial outer membrane);GO:0005777(peroxisome);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005794(Golgi apparatus);GO:0005829(cytosol);GO:0005874(microtubule);GO:0005903(brush border);GO:0005905(clathrin-coated pit);GO:0006816(calcium ion transport);GO:0006897(endocytosis);GO:0007005(mitochondrion organization);GO:0008017(microtubule binding);GO:0008289(lipid binding);GO:0008637(apoptotic mitochondrial changes);GO:0010468(regulation of gene expression);GO:0010637(negative regulation of mitochondrial fusion);GO:0010821(regulation of mitochondrion organization);GO:0012501(programmed cell death);GO:0012505(endomembrane system);GO:0016020(membrane);GO:0016559(peroxisome fission);GO:0016787(hydrolase activity);GO:0017137(Rab GTPase binding);GO:0030054(cell junction);GO:0030276(clathrin binding);GO:0030672(synaptic vesicle membrane);GO:0030742(GTP-dependent protein binding);GO:0031410(cytoplasmic vesicle);GO:0031625(ubiquitin protein ligase binding);GO:0031966(mitochondrial membrane);GO:0032459(regulation of protein oligomerization);GO:0032991(protein-containing complex);GO:0036466(synaptic vesicle recycling via endosome);GO:0042803(protein homodimerization activity);GO:0043065(positive regulation of apoptotic process);GO:0043231(intracellular membrane-bounded organelle);GO:0043547(positive regulation of GTPase activity);GO:0043653(mitochondrial fragmentation involved in apoptotic process);GO:0044877(protein-containing complex binding);GO:0045202(synapse);GO:0048312(intracellular distribution of mitochondria);GO:0048471(perinuclear region of cytoplasm);GO:0048488(synaptic vesicle endocytosis);GO:0050714(positive regulation of protein secretion);GO:0051259(protein complex oligomerization);GO:0051260(protein homooligomerization);GO:0051289(protein homotetramerization);GO:0051433(BH2 domain binding);GO:0060047(heart contraction);GO:0061003(positive regulation of dendritic spine morphogenesis);GO:0061025(membrane fusion);GO:0070266(necroptotic process);GO:0070584(mitochondrion morphogenesis);GO:0070585(protein localization to mitochondrion);GO:0071396(cellular response to lipid);GO:0090141(positive regulation of mitochondrial fission);GO:0090149(mitochondrial membrane fission);GO:0090200(positive regulation of release of cytochrome c from mitochondria);GO:0090650(cellular response to oxygen-glucose deprivation);GO:0097194(execution phase of apoptosis);GO:0098794(postsynapse);GO:0098835(presynaptic endocytic zone membrane);GO:0099073(mitochondrion-derived vesicle);GO:0099503(secretory vesicle);GO:1900063(regulation of peroxisome organization);GO:1900244(positive regulation of synaptic vesicle endocytosis);GO:1903146(regulation of autophagy of mitochondrion);GO:1903578(regulation of ATP metabolic process);GO:1904579(cellular response to thapsigargin);GO:1904666(regulation of ubiquitin protein ligase activity);GO:1905395(response to flavonoid);GO:1990910(response to hypobaric hypoxia);GO:2000302(positive regulation of synaptic vesicle exocytosis);GO:2001244(positive regulation of intrinsic apoptotic signaling pathway)","04217(Necroptosis);04621(NOD-like receptor signaling pathway);04668(TNF signaling pathway)","K17065","EC:3.6.5.5","dynamin 1 like [Source:HGNC Symbol;Acc:HGNC:2973]",{"v":0.088465,"d":"0.09"},{"v":0.013872,"d":"0.01"},{"v":0.020789,"d":"0.02"},0,{"v":0.065746,"d":"0.07"},{"v":0.056404,"d":"0.06"},{"v":1.0079901760131,"d":"1.01"},{"v":0.0114815782363907,"d":"0.01"},1,1,"up","no"]
[5489,0,"chr1","+",44674780,44724343,"ENST00000444751",6,656,"ENSG00000198520","ARMH1","NA","NA","NA","NA","armadillo-like helical domain containing 1 [Source:HGNC Symbol;Acc:HGNC:34345]",0,{"v":0.02643,"d":"0.03"},{"v":0.16992,"d":"0.17"},{"v":0.039186,"d":"0.04"},{"v":0.234526,"d":"0.23"},{"v":0.081223,"d":"0.08"},{"v":0.553199881668474,"d":"0.55"},{"v":-0.854127246996792,"d":"-0.85"},1,1,"down","no"]
[189622,0,"chr8","+",61714788,61714859,"ENST00000583453",1,72,"ENSG00000264408","MIR4470","NA","NA","NA","NA","microRNA 4470 [Source:HGNC Symbol;Acc:HGNC:41833]",{"v":0.095132,"d":"0.10"},0,0,{"v":0.020709,"d":"0.02"},{"v":0.03066,"d":"0.03"},{"v":0.131034,"d":"0.13"},{"v":0.521548439444527,"d":"0.52"},{"v":-0.939126843866097,"d":"-0.94"},1,1,"down","no"]
[119238,0,"chr2","+",171922462,171923475,"ENST00000460481",2,600,"ENSG00000128708","HAT1","GO:0000784(nuclear chromosome, telomeric region);GO:0000790(nuclear chromatin);GO:0004402(histone acetyltransferase activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0006323(DNA packaging);GO:0006325(chromatin organization);GO:0006335(DNA replication-dependent nucleosome assembly);GO:0006336(DNA replication-independent nucleosome assembly);GO:0006348(chromatin silencing at telomere);GO:0006475(internal protein amino acid acetylation);GO:0007584(response to nutrient);GO:0010485(H4 histone acetyltransferase activity);GO:0016363(nuclear matrix);GO:0016573(histone acetylation);GO:0016740(transferase activity);GO:0016746(transferase activity, transferring acyl groups);GO:0032991(protein-containing complex);GO:0042393(histone binding);GO:0043231(intracellular membrane-bounded organelle);GO:0043967(histone H4 acetylation)","05034(Alcoholism)","K11303","EC:2.3.1.48","histone acetyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:4821]",{"v":0.4948,"d":"0.49"},0,{"v":0.280399,"d":"0.28"},{"v":0.140304,"d":"0.14"},{"v":0.329987,"d":"0.33"},{"v":0.1599,"d":"0.16"},{"v":1.23010166758967,"d":"1.23"},{"v":0.298777558870146,"d":"0.30"},1,1,"up","no"]
[8366,0,"chr1","-",93338915,93345800,"ENST00000438777",6,752,"ENSG00000223745","CCDC18-AS1","NA","NA","NA","NA","CCDC18 antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:52262]",{"v":0.15745,"d":"0.16"},{"v":0.16615,"d":"0.17"},{"v":0.227794,"d":"0.23"},{"v":0.045052,"d":"0.05"},{"v":0.180753,"d":"0.18"},{"v":0.335118,"d":"0.34"},{"v":0.983011928553473,"d":"0.98"},{"v":-0.0247191715457934,"d":"-0.02"},1,1,"down","no"]
[25425,0,"chr10","-",133278630,133309156,"ENST00000543663",19,4302,"ENSG00000130640","TUBGCP2","GO:0000226(microtubule cytoskeleton organization);GO:0000278(mitotic cell cycle);GO:0000922(spindle pole);GO:0000923(equatorial microtubule organizing center);GO:0000930(gamma-tubulin complex);GO:0005515(protein binding);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0005813(centrosome);GO:0005815(microtubule organizing center);GO:0005829(cytosol);GO:0005856(cytoskeleton);GO:0005874(microtubule);GO:0005881(cytoplasmic microtubule);GO:0007020(microtubule nucleation);GO:0008275(gamma-tubulin small complex);GO:0016020(membrane);GO:0031122(cytoplasmic microtubule organization);GO:0043015(gamma-tubulin binding);GO:0051011(microtubule minus-end binding);GO:0051225(spindle assembly);GO:0051321(meiotic cell cycle);GO:0051415(microtubule nucleation by interphase microtubule organizing center);GO:0065003(protein-containing complex assembly)","NA","K16569","NA","tubulin gamma complex associated protein 2 [Source:HGNC Symbol;Acc:HGNC:18599]",{"v":0.004767,"d":"0.00"},{"v":0.005304,"d":"0.01"},{"v":0.004666,"d":"0.00"},{"v":0.00357,"d":"0.00"},{"v":0.009167,"d":"0.01"},{"v":0.005026,"d":"0.01"},{"v":0.82964589314868,"d":"0.83"},{"v":-0.269432393616253,"d":"-0.27"},1,1,"down","no"]
[85443,0,"chr17","-",41523988,41524751,"ENST00000471565",2,654,"ENSG00000171345","KRT19","GO:0005198(structural molecule activity);GO:0005200(structural constituent of cytoskeleton);GO:0005515(protein binding);GO:0005829(cytosol);GO:0005882(intermediate filament);GO:0005886(plasma membrane);GO:0007219(Notch signaling pathway);GO:0008307(structural constituent of muscle);GO:0016010(dystrophin-associated glycoprotein complex);GO:0016032(viral process);GO:0016327(apicolateral plasma membrane);GO:0030018(Z disc);GO:0031424(keratinization);GO:0042383(sarcolemma);GO:0043034(costamere);GO:0043627(response to estrogen);GO:0044877(protein-containing complex binding);GO:0045214(sarcomere organization);GO:0060706(cell differentiation involved in embryonic placenta development);GO:0070062(extracellular exosome);GO:0070268(cornification);GO:0071944(cell periphery);GO:1990357(terminal web)","04915(Estrogen signaling pathway)","K07604","NA","keratin 19 [Source:HGNC Symbol;Acc:HGNC:6436]",{"v":0.000992,"d":"0.00"},{"v":0.039495,"d":"0.04"},{"v":0.001274,"d":"0.00"},{"v":0.001667,"d":"0.00"},{"v":0.001763,"d":"0.00"},{"v":0.001746,"d":"0.00"},{"v":8.06819938176198,"d":"8.07"},{"v":3.01224673634615,"d":"3.01"},1,1,"up","no"]
[80363,0,"chr17","-",5386102,5419466,"ENST00000225696",17,2194,"ENSG00000108559","NUP88","GO:0000055(ribosomal large subunit export from nucleus);GO:0000056(ribosomal small subunit export from nucleus);GO:0000278(mitotic cell cycle);GO:0005215(transporter activity);GO:0005623(cell);GO:0005634(nucleus);GO:0005643(nuclear pore);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0006110(regulation of glycolytic process);GO:0006406(mRNA export from nucleus);GO:0006409(tRNA export from nucleus);GO:0006606(protein import into nucleus);GO:0006611(protein export from nucleus);GO:0006913(nucleocytoplasmic transport);GO:0015031(protein transport);GO:0016032(viral process);GO:0016925(protein sumoylation);GO:0017056(structural constituent of nuclear pore);GO:0019083(viral transcription);GO:0043657(host cell);GO:0051028(mRNA transport);GO:0060964(regulation of gene silencing by miRNA);GO:0075733(intracellular transport of virus);GO:1900034(regulation of cellular response to heat)","03013(RNA transport)","K14318","NA","nucleoporin 88 [Source:HGNC Symbol;Acc:HGNC:8067]",0,0,0,{"v":0.369831,"d":"0.37"},0,0,"-inf","-inf",1,1,"down","no"]
[205421,0,"chrX","-",109623700,109625172,"ENST00000372101",1,1473,"ENSG00000176076","KCNE5","GO:0005249(voltage-gated potassium channel activity);GO:0005251(delayed rectifier potassium channel activity);GO:0005515(protein binding);GO:0005886(plasma membrane);GO:0006811(ion transport);GO:0008016(regulation of heart contraction);GO:0008076(voltage-gated potassium channel complex);GO:0015459(potassium channel regulator activity);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0044325(ion channel binding);GO:0060048(cardiac muscle contraction);GO:0060306(regulation of membrane repolarization);GO:0060307(regulation of ventricular cardiac muscle cell membrane repolarization);GO:0060372(regulation of atrial cardiac muscle cell membrane repolarization);GO:0086005(ventricular cardiac muscle cell action potential);GO:0086008(voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization);GO:0086011(membrane repolarization during action potential);GO:0086013(membrane repolarization during cardiac muscle cell action potential);GO:0086014(atrial cardiac muscle cell action potential);GO:0086091(regulation of heart rate by cardiac conduction);GO:0097623(potassium ion export across plasma membrane);GO:0098915(membrane repolarization during ventricular cardiac muscle cell action potential);GO:1901379(regulation of potassium ion transmembrane transport);GO:1901380(negative regulation of potassium ion transmembrane transport);GO:1901381(positive regulation of potassium ion transmembrane transport);GO:1902260(negative regulation of delayed rectifier potassium channel activity);GO:1902282(voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization);GO:1903765(negative regulation of potassium ion export across plasma membrane);GO:2001257(regulation of cation channel activity)","NA","K04895","NA","potassium voltage-gated channel subfamily E regulatory subunit 5 [Source:HGNC Symbol;Acc:HGNC:6241]",{"v":0.105233,"d":"0.11"},{"v":0.204474,"d":"0.20"},{"v":0.074624,"d":"0.07"},{"v":0.114083,"d":"0.11"},{"v":0.088046,"d":"0.09"},{"v":0.180619,"d":"0.18"},{"v":1.00413588052714,"d":"1.00"},{"v":0.00595450922722873,"d":"0.01"},1,1,"up","no"]
[33696,0,"chr11","+",71929076,71996420,"ENST00000525243",7,812,"ENSG00000137522","RNF121","GO:0000139(Golgi membrane);GO:0005789(endoplasmic reticulum membrane);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016567(protein ubiquitination);GO:0030433(ubiquitin-dependent ERAD pathway);GO:0030968(endoplasmic reticulum unfolded protein response);GO:0046872(metal ion binding);GO:0061630(ubiquitin protein ligase activity)","NA","K15698","NA","ring finger protein 121 [Source:HGNC Symbol;Acc:HGNC:21070]",{"v":0.151161,"d":"0.15"},{"v":0.186915,"d":"0.19"},{"v":0.465814,"d":"0.47"},{"v":0.143971,"d":"0.14"},0,{"v":0.002776,"d":"0.00"},{"v":5.47806769473993,"d":"5.48"},{"v":2.45366709413058,"d":"2.45"},1,1,"up","no"]
[37724,0,"chr11","+",124876470,124881466,"ENST00000529658",9,2272,"ENSG00000154134","ROBO3","GO:0005515(protein binding);GO:0005886(plasma membrane);GO:0006935(chemotaxis);GO:0007156(homophilic cell adhesion via plasma membrane adhesion molecules);GO:0007275(multicellular organism development);GO:0007399(nervous system development);GO:0007411(axon guidance);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016199(axon midline choice point recognition);GO:0030154(cell differentiation);GO:0030424(axon);GO:0035385(Roundabout signaling pathway);GO:0061642(chemoattraction of axon);GO:0070593(dendrite self-avoidance);GO:0071679(commissural neuron axon guidance);GO:0098632(cell-cell adhesion mediator activity)","04360(Axon guidance)","K06755","NA","roundabout guidance receptor 3 [Source:HGNC Symbol;Acc:HGNC:13433]",{"v":0.301158,"d":"0.30"},0,{"v":0.283594,"d":"0.28"},0,0,0,"inf","inf",1,1,"up","no"]
[43407,0,"chr12","+",53295542,53296706,"ENST00000551223",3,478,"ENSG00000123349","PFDN5","GO:0003714(transcription corepressor activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0006355(regulation of transcription, DNA-templated);GO:0006457(protein folding);GO:0016272(prefoldin complex);GO:0045892(negative regulation of transcription, DNA-templated);GO:0051082(unfolded protein binding);GO:0060041(retina development in camera-type eye);GO:0090090(negative regulation of canonical Wnt signaling pathway)","NA","K04797","NA","prefoldin subunit 5 [Source:HGNC Symbol;Acc:HGNC:8869]",{"v":1.069146,"d":"1.07"},{"v":0.119454,"d":"0.12"},{"v":0.000164,"d":"0.00"},{"v":0.000959,"d":"0.00"},{"v":1.097556,"d":"1.10"},{"v":7.8e-5,"d":"0.00"},{"v":1.08207862238336,"d":"1.08"},{"v":0.113805327262423,"d":"0.11"},1,1,"up","no"]
[122723,0,"chr2","-",227002711,227164236,"ENST00000396625",48,10018,"ENSG00000081052","COL4A4","GO:0001525(angiogenesis);GO:0001886(endothelial cell morphogenesis);GO:0005201(extracellular matrix structural constituent);GO:0005576(extracellular region);GO:0005581(collagen trimer);GO:0005587(collagen type IV trimer);GO:0005604(basement membrane);GO:0005615(extracellular space);GO:0005788(endoplasmic reticulum lumen);GO:0030020(extracellular matrix structural constituent conferring tensile strength);GO:0030198(extracellular matrix organization);GO:0031012(extracellular matrix);GO:0032836(glomerular basement membrane development);GO:0062023(collagen-containing extracellular matrix)","04151(PI3K-Akt signaling pathway);04510(Focal adhesion);04512(ECM-receptor interaction);04926(Relaxin signaling pathway);04933(AGE-RAGE signaling pathway in diabetic complications);04974(Protein digestion and absorption);05146(Amoebiasis);05165(Human papillomavirus infection);05200(Pathways in cancer);05222(Small cell lung cancer)","NA","NA","collagen type IV alpha 4 chain [Source:HGNC Symbol;Acc:HGNC:2206]",{"v":0.036942,"d":"0.04"},{"v":0.013163,"d":"0.01"},{"v":0.043858,"d":"0.04"},{"v":0.014309,"d":"0.01"},0,{"v":0.008852,"d":"0.01"},{"v":4.05694918181426,"d":"4.06"},{"v":2.02039523116047,"d":"2.02"},1,1,"up","no"]
[4901,0,"chr1","+",41014590,41043890,"ENST00000626479",4,4800,"ENSG00000281207","SLFNL1-AS1","NA","NA","NA","NA","SLFNL1 antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:44126]",{"v":0.059699,"d":"0.06"},{"v":0.050328,"d":"0.05"},{"v":0.098885,"d":"0.10"},{"v":0.095206,"d":"0.10"},{"v":0.052155,"d":"0.05"},{"v":0.051806,"d":"0.05"},{"v":1.0489287884037,"d":"1.05"},{"v":0.0689167369198132,"d":"0.07"},1,1,"up","no"]
[65596,0,"chr15","+",66504959,66548426,"ENST00000535141",18,2206,"ENSG00000174442","ZWILCH","GO:0000775(chromosome, centromeric region);GO:0000776(kinetochore);GO:0000777(condensed chromosome kinetochore);GO:0005515(protein binding);GO:0005694(chromosome);GO:0005829(cytosol);GO:0007049(cell cycle);GO:0007093(mitotic cell cycle checkpoint);GO:0051301(cell division);GO:1990423(RZZ complex)","NA","K11579","NA","zwilch kinetochore protein [Source:HGNC Symbol;Acc:HGNC:25468]",{"v":0.778075,"d":"0.78"},0,{"v":0.265353,"d":"0.27"},{"v":0.291831,"d":"0.29"},{"v":0.045533,"d":"0.05"},0,{"v":3.09288483655636,"d":"3.09"},{"v":1.6289531157349,"d":"1.63"},1,1,"up","no"]
[41437,0,"chr12","+",31324316,31325829,"ENST00000313737",1,1514,"ENSG00000177340","AC024940","NA","NA","NA","NA","novel transcript, antisense to FAM60A",{"v":0.276759,"d":"0.28"},{"v":0.098561,"d":"0.10"},{"v":0.187429,"d":"0.19"},{"v":0.04166,"d":"0.04"},0,0,{"v":13.5081373019683,"d":"13.51"},{"v":3.75575684353417,"d":"3.76"},1,1,"up","no"]
[103750,0,"chr19","+",39481225,39486495,"ENST00000594583",8,680,"ENSG00000105197","TIMM50","GO:0001836(release of cytochrome c from mitochondria);GO:0003723(RNA binding);GO:0004721(phosphoprotein phosphatase activity);GO:0004722(protein serine/threonine phosphatase activity);GO:0004725(protein tyrosine phosphatase activity);GO:0005134(interleukin-2 receptor binding);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005739(mitochondrion);GO:0005743(mitochondrial inner membrane);GO:0005744(TIM23 mitochondrial import inner membrane translocase complex);GO:0006470(protein dephosphorylation);GO:0007006(mitochondrial membrane organization);GO:0015031(protein transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016607(nuclear speck);GO:0030150(protein import into mitochondrial matrix);GO:0035335(peptidyl-tyrosine dephosphorylation);GO:0043021(ribonucleoprotein complex binding)","NA","K17496","NA","translocase of inner mitochondrial membrane 50 [Source:HGNC Symbol;Acc:HGNC:23656]",0,0,0,0,0,{"v":0.006243,"d":"0.01"},"-inf","-inf",1,1,"down","no"]
[172707,0,"chr6","-",100715130,100881364,"ENST00000522650",13,2828,"ENSG00000112249","ASCC3","GO:0000166(nucleotide binding);GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0004386(helicase activity);GO:0005515(protein binding);GO:0005524(ATP binding);GO:0005622(intracellular);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0006281(DNA repair);GO:0006307(DNA dealkylation involved in DNA repair);GO:0006974(cellular response to DNA damage stimulus);GO:0008026(ATP-dependent helicase activity);GO:0008283(cell population proliferation);GO:0016020(membrane);GO:0016607(nuclear speck);GO:0016787(hydrolase activity);GO:0032508(DNA duplex unwinding);GO:0043140(ATP-dependent 3'-5' DNA helicase activity);GO:0099053(activating signal cointegrator 1 complex)","NA","K18663","EC:3.6.4.12","activating signal cointegrator 1 complex subunit 3 [Source:HGNC Symbol;Acc:HGNC:18697]",{"v":0.142235,"d":"0.14"},{"v":0.129426,"d":"0.13"},{"v":0.141105,"d":"0.14"},{"v":0.22028,"d":"0.22"},{"v":0.198185,"d":"0.20"},{"v":0.148844,"d":"0.15"},{"v":0.727585848276689,"d":"0.73"},{"v":-0.45881061239768,"d":"-0.46"},1,1,"down","no"]
[207970,0,"chrY","+",12701231,12860839,"ENST00000338981",46,10036,"ENSG00000114374","USP9Y","GO:0004197(cysteine-type endopeptidase activity);GO:0004843(thiol-dependent ubiquitin-specific protease activity);GO:0005737(cytoplasm);GO:0006508(proteolysis);GO:0006511(ubiquitin-dependent protein catabolic process);GO:0007179(transforming growth factor beta receptor signaling pathway);GO:0007283(spermatogenesis);GO:0008233(peptidase activity);GO:0008234(cysteine-type peptidase activity);GO:0016579(protein deubiquitination);GO:0016787(hydrolase activity);GO:0030509(BMP signaling pathway);GO:0036459(thiol-dependent ubiquitinyl hydrolase activity);GO:0070410(co-SMAD binding)","NA","K11840","EC:3.4.19.12","ubiquitin specific peptidase 9 Y-linked [Source:HGNC Symbol;Acc:HGNC:12633]",0,0,0,0,{"v":0.005169,"d":"0.01"},0,"-inf","-inf",1,1,"down","no"]
[82659,0,"chr17","+",19237396,19283185,"ENST00000583197",4,637,"ENSG00000072134","EPN2","GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0006897(endocytosis);GO:0008289(lipid binding);GO:0030128(clathrin coat of endocytic vesicle);GO:0030136(clathrin-coated vesicle);GO:0030948(negative regulation of vascular endothelial growth factor receptor signaling pathway);GO:0031410(cytoplasmic vesicle);GO:0043231(intracellular membrane-bounded organelle);GO:0045296(cadherin binding);GO:0045747(positive regulation of Notch signaling pathway);GO:0061024(membrane organization);GO:1903671(negative regulation of sprouting angiogenesis)","04144(Endocytosis)","K12471","NA","epsin 2 [Source:HGNC Symbol;Acc:HGNC:18639]",0,0,0,0,0,0,1,0,1,1,"no","no"]
[32829,0,"chr11","-",66564742,66566134,"ENST00000530565",4,555,"ENSG00000174080","CTSF","GO:0004197(cysteine-type endopeptidase activity);GO:0005615(extracellular space);GO:0005764(lysosome);GO:0006508(proteolysis);GO:0008233(peptidase activity);GO:0008234(cysteine-type peptidase activity);GO:0016787(hydrolase activity);GO:0019886(antigen processing and presentation of exogenous peptide antigen via MHC class II);GO:0043202(lysosomal lumen);GO:0051603(proteolysis involved in cellular protein catabolic process);GO:0062023(collagen-containing extracellular matrix);GO:0070062(extracellular exosome);GO:1903561(extracellular vesicle)","04142(Lysosome);04210(Apoptosis)","K01373","EC:3.4.22.41","cathepsin F [Source:HGNC Symbol;Acc:HGNC:2531]",{"v":0.488028,"d":"0.49"},{"v":0.425146,"d":"0.43"},{"v":0.651859,"d":"0.65"},{"v":0.009715,"d":"0.01"},{"v":0.43523,"d":"0.44"},{"v":0.343151,"d":"0.34"},{"v":1.98584055749553,"d":"1.99"},{"v":0.989749793991842,"d":"0.99"},1,1,"up","no"]
[74905,0,"chr16","+",53157164,53250175,"ENST00000564255",16,2896,"ENSG00000177200","CHD9","GO:0000166(nucleotide binding);GO:0003677(DNA binding);GO:0004386(helicase activity);GO:0005515(protein binding);GO:0005524(ATP binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0006325(chromatin organization);GO:0016787(hydrolase activity);GO:0016817(hydrolase activity, acting on acid anhydrides);GO:0019216(regulation of lipid metabolic process)","NA","K14438","EC:3.6.4.12","chromodomain helicase DNA binding protein 9 [Source:HGNC Symbol;Acc:HGNC:25701]",{"v":0.218576,"d":"0.22"},{"v":0.36572,"d":"0.37"},{"v":0.208185,"d":"0.21"},{"v":0.09154,"d":"0.09"},{"v":0.257181,"d":"0.26"},{"v":0.179408,"d":"0.18"},{"v":1.50054437457515,"d":"1.50"},{"v":0.585485983403317,"d":"0.59"},1,1,"up","no"]
[106712,0,"chr19","+",49969673,49975814,"ENST00000602139",10,2510,"ENSG00000161643","SIGLEC16","NA","NA","NA","NA","sialic acid binding Ig like lectin 16 (gene/pseudogene) [Source:HGNC Symbol;Acc:HGNC:24851]",{"v":0.108207,"d":"0.11"},{"v":0.052413,"d":"0.05"},0,{"v":0.025129,"d":"0.03"},{"v":0.040969,"d":"0.04"},{"v":0.025998,"d":"0.03"},{"v":1.74404968728284,"d":"1.74"},{"v":0.802441142508999,"d":"0.80"},1,1,"up","no"]
[25972,0,"chr11","+",835551,836360,"ENST00000526439",2,713,"ENSG00000177697","CD151","GO:0005178(integrin binding);GO:0005515(protein binding);GO:0005604(basement membrane);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0005887(integral component of plasma membrane);GO:0005925(focal adhesion);GO:0007155(cell adhesion);GO:0007166(cell surface receptor signaling pathway);GO:0009986(cell surface);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016477(cell migration);GO:0030335(positive regulation of cell migration);GO:0031581(hemidesmosome assembly);GO:0042098(T cell proliferation);GO:0044319(wound healing, spreading of cells);GO:0045807(positive regulation of endocytosis)","NA","NA","NA","CD151 molecule (Raph blood group) [Source:HGNC Symbol;Acc:HGNC:1630]",{"v":0.705069,"d":"0.71"},{"v":0.360177,"d":"0.36"},{"v":0.290308,"d":"0.29"},{"v":0.362513,"d":"0.36"},{"v":0.307296,"d":"0.31"},{"v":0.378757,"d":"0.38"},{"v":1.29276936311114,"d":"1.29"},{"v":0.370464913682425,"d":"0.37"},1,1,"up","no"]
[62113,0,"chr15","+",29822631,29824081,"ENST00000557989",1,1451,"ENSG00000259523","AC022613","NA","NA","NA","NA","novel transcript, antisense to TJP1",{"v":0.20124,"d":"0.20"},{"v":0.151648,"d":"0.15"},{"v":0.113042,"d":"0.11"},{"v":0.141093,"d":"0.14"},{"v":0.160885,"d":"0.16"},{"v":0.060794,"d":"0.06"},{"v":1.28436042472958,"d":"1.28"},{"v":0.361050116792635,"d":"0.36"},1,1,"up","no"]
[22476,0,"chr10","+",79285453,79316528,"ENST00000446377",20,6686,"ENSG00000108175","ZMIZ1","GO:0001570(vasculogenesis);GO:0001701(in utero embryonic development);GO:0003007(heart morphogenesis);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0007296(vitellogenesis);GO:0007569(cell aging);GO:0008270(zinc ion binding);GO:0016607(nuclear speck);GO:0043231(intracellular membrane-bounded organelle);GO:0045582(positive regulation of T cell differentiation);GO:0045747(positive regulation of Notch signaling pathway);GO:0045944(positive regulation of transcription by RNA polymerase II);GO:0046872(metal ion binding);GO:0048146(positive regulation of fibroblast proliferation);GO:0048589(developmental growth);GO:0048844(artery morphogenesis)","NA","K22403","NA","zinc finger MIZ-type containing 1 [Source:HGNC Symbol;Acc:HGNC:16493]",{"v":0.000323,"d":"0.00"},0,{"v":0.001936,"d":"0.00"},{"v":0.000324,"d":"0.00"},{"v":0.001101,"d":"0.00"},0,{"v":1.58526315789474,"d":"1.59"},{"v":0.664722351453618,"d":"0.66"},1,1,"up","no"]
[25846,0,"chr11","+",747417,756284,"ENST00000532685",2,568,"ENSG00000177156","TALDO1","GO:0003824(catalytic activity);GO:0004801(sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glyceronetransferase activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005975(carbohydrate metabolic process);GO:0005999(xylulose biosynthetic process);GO:0006002(fructose 6-phosphate metabolic process);GO:0006098(pentose-phosphate shunt);GO:0009052(pentose-phosphate shunt, non-oxidative branch);GO:0016740(transferase activity);GO:0019682(glyceraldehyde-3-phosphate metabolic process);GO:0030246(carbohydrate binding);GO:0035722(interleukin-12-mediated signaling pathway);GO:0043231(intracellular membrane-bounded organelle);GO:0048029(monosaccharide binding);GO:0070062(extracellular exosome)","00030(Pentose phosphate pathway)","K00616","EC:2.2.1.2","transaldolase 1 [Source:HGNC Symbol;Acc:HGNC:11559]",{"v":0.193294,"d":"0.19"},{"v":0.424352,"d":"0.42"},{"v":0.121902,"d":"0.12"},{"v":0.343019,"d":"0.34"},{"v":0.328198,"d":"0.33"},{"v":0.173796,"d":"0.17"},{"v":0.875191269246745,"d":"0.88"},{"v":-0.192329748755579,"d":"-0.19"},1,1,"down","no"]
[173375,0,"chr6","-",116267760,116279887,"ENST00000652202",3,5875,"ENSG00000189241","TSPYL1","GO:0005634(nucleus);GO:0005730(nucleolus);GO:0006334(nucleosome assembly);GO:0008150(biological_process);GO:0019899(enzyme binding)","NA","K11284","NA","TSPY like 1 [Source:HGNC Symbol;Acc:HGNC:12382]",{"v":0.02829,"d":"0.03"},{"v":0.013858,"d":"0.01"},{"v":0.015396,"d":"0.02"},{"v":0.002013,"d":"0.00"},{"v":0.004415,"d":"0.00"},{"v":0.013061,"d":"0.01"},{"v":2.95263995074144,"d":"2.95"},{"v":1.56200544284192,"d":"1.56"},1,1,"up","no"]
[108456,0,"chr19","+",55707550,55707855,"ENST00000597650",1,306,"ENSG00000268593","AC008749","NA","NA","NA","NA","Vomeronasal type-1 receptor 1, pseudogene",{"v":0.019552,"d":"0.02"},{"v":0.006375,"d":"0.01"},{"v":0.041909,"d":"0.04"},0,0,0,"inf","inf",1,1,"up","no"]
[83958,0,"chr17","+",31391935,31392658,"ENST00000581280",2,453,"ENSG00000131242","RAB11FIP4","GO:0003407(neural retina development);GO:0005509(calcium ion binding);GO:0005515(protein binding);GO:0005615(extracellular space);GO:0005737(cytoplasm);GO:0005768(endosome);GO:0005813(centrosome);GO:0005815(microtubule organizing center);GO:0005819(spindle);GO:0005856(cytoskeleton);GO:0016020(membrane);GO:0016032(viral process);GO:0017137(Rab GTPase binding);GO:0030139(endocytic vesicle);GO:0030306(ADP-ribosylation factor binding);GO:0030496(midbody);GO:0031410(cytoplasmic vesicle);GO:0032154(cleavage furrow);GO:0032456(endocytic recycling);GO:0032465(regulation of cytokinesis);GO:0042803(protein homodimerization activity);GO:0046872(metal ion binding);GO:0048471(perinuclear region of cytoplasm);GO:0055038(recycling endosome membrane);GO:1903452(positive regulation of G1 to G0 transition)","04144(Endocytosis)","K12485","NA","RAB11 family interacting protein 4 [Source:HGNC Symbol;Acc:HGNC:30267]",0,0,{"v":0.087517,"d":"0.09"},0,0,0,"inf","inf",1,1,"up","no"]
[131382,0,"chr21","+",46690764,46691226,"ENST00000427757",1,463,"ENSG00000212932","RPL23AP4","NA","NA","NA","NA","ribosomal protein L23a pseudogene 4 [Source:HGNC Symbol;Acc:HGNC:10321]",{"v":0.459557,"d":"0.46"},{"v":0.287431,"d":"0.29"},{"v":0.022478,"d":"0.02"},{"v":0.124874,"d":"0.12"},{"v":0.822772,"d":"0.82"},0,{"v":0.8119762020839,"d":"0.81"},{"v":-0.300490650283147,"d":"-0.30"},1,1,"down","no"]
[21878,0,"chr10","-",72475267,72626111,"ENST00000604238",10,1268,"ENSG00000107745","MICU1","GO:0005509(calcium ion binding);GO:0005515(protein binding);GO:0005622(intracellular);GO:0005739(mitochondrion);GO:0005743(mitochondrial inner membrane);GO:0005758(mitochondrial intermembrane space);GO:0006811(ion transport);GO:0006816(calcium ion transport);GO:0006851(mitochondrial calcium ion transmembrane transport);GO:0006952(defense response);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0032592(integral component of mitochondrial membrane);GO:0034704(calcium channel complex);GO:0036444(calcium import into the mitochondrion);GO:0042802(identical protein binding);GO:0046872(metal ion binding);GO:0046982(protein heterodimerization activity);GO:0051260(protein homooligomerization);GO:0051560(mitochondrial calcium ion homeostasis);GO:0051561(positive regulation of mitochondrial calcium ion concentration);GO:0070509(calcium ion import);GO:1900069(regulation of cellular hyperosmotic salinity response);GO:1990246(uniplex complex)","NA","K22827","NA","mitochondrial calcium uptake 1 [Source:HGNC Symbol;Acc:HGNC:1530]",{"v":0.019489,"d":"0.02"},{"v":0.015138,"d":"0.02"},{"v":1.850049,"d":"1.85"},0,{"v":0.139911,"d":"0.14"},{"v":0.030283,"d":"0.03"},{"v":11.0736923745843,"d":"11.07"},{"v":3.46906444458584,"d":"3.47"},1,1,"up","no"]
[174281,0,"chr6","-",136231024,136250324,"ENST00000451457",8,1524,"ENSG00000146410","MTFR2","GO:0000266(mitochondrial fission);GO:0005515(protein binding);GO:0005739(mitochondrion);GO:0007005(mitochondrion organization);GO:0009060(aerobic respiration)","NA","NA","NA","mitochondrial fission regulator 2 [Source:HGNC Symbol;Acc:HGNC:21115]",0,0,0,0,0,0,1,0,1,1,"no","no"]
[148321,0,"chr3","+",195689337,195699314,"ENST00000628823",3,616,"ENSG00000242086","MUC20-OT1","NA","NA","NA","NA","MUC20 overlapping transcript [Source:HGNC Symbol;Acc:HGNC:53807]",{"v":0.951126,"d":"0.95"},{"v":0.852734,"d":"0.85"},{"v":0.786961,"d":"0.79"},{"v":0.323693,"d":"0.32"},{"v":0.771335,"d":"0.77"},{"v":1.383552,"d":"1.38"},{"v":1.04528439671102,"d":"1.05"},{"v":0.0638955182903746,"d":"0.06"},1,1,"up","no"]
[111917,0,"chr2","+",44168910,44231472,"ENST00000345249",5,1713,"ENSG00000138032","PPM1B","GO:0000287(magnesium ion binding);GO:0003824(catalytic activity);GO:0004721(phosphoprotein phosphatase activity);GO:0004722(protein serine/threonine phosphatase activity);GO:0004724(magnesium-dependent protein serine/threonine phosphatase activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005730(nucleolus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0006470(protein dephosphorylation);GO:0006499(N-terminal protein myristoylation);GO:0016020(membrane);GO:0016787(hydrolase activity);GO:0030145(manganese ion binding);GO:0032688(negative regulation of interferon-beta production);GO:0035970(peptidyl-threonine dephosphorylation);GO:0043124(negative regulation of I-kappaB kinase/NF-kappaB signaling);GO:0043169(cation binding);GO:0046872(metal ion binding);GO:0050687(negative regulation of defense response to virus);GO:1901223(negative regulation of NIK/NF-kappaB signaling)","04010(MAPK signaling pathway)","NA","NA","protein phosphatase, Mg2+/Mn2+ dependent 1B [Source:HGNC Symbol;Acc:HGNC:9276]",0,0,0,0,0,0,1,0,1,1,"no","no"]
[190691,0,"chr8","+",86514562,86529049,"ENST00000522240",4,446,"ENSG00000085719","CPNE3","GO:0003723(RNA binding);GO:0004674(protein serine/threonine kinase activity);GO:0005215(transporter activity);GO:0005515(protein binding);GO:0005544(calcium-dependent phospholipid binding);GO:0005634(nucleus);GO:0005730(nucleolus);GO:0005737(cytoplasm);GO:0005739(mitochondrion);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0005925(focal adhesion);GO:0006468(protein phosphorylation);GO:0006629(lipid metabolic process);GO:0016020(membrane);GO:0016192(vesicle-mediated transport);GO:0030054(cell junction);GO:0030335(positive regulation of cell migration);GO:0030971(receptor tyrosine kinase binding);GO:0035577(azurophil granule membrane);GO:0038128(ERBB2 signaling pathway);GO:0043312(neutrophil degranulation);GO:0046474(glycerophospholipid biosynthetic process);GO:0048306(calcium-dependent protein binding);GO:0070062(extracellular exosome);GO:0071277(cellular response to calcium ion);GO:0071363(cellular response to growth factor stimulus)","NA","NA","NA","copine 3 [Source:HGNC Symbol;Acc:HGNC:2316]",0,0,0,{"v":0.059338,"d":"0.06"},0,0,"-inf","-inf",1,1,"down","no"]
[56482,0,"chr14","-",50396158,50396881,"ENST00000530553",2,311,"ENSG00000100490","CDKL1","GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0004693(cyclin-dependent protein serine/threonine kinase activity);GO:0005524(ATP binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0006468(protein phosphorylation);GO:0007507(heart development);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0016740(transferase activity);GO:0035869(ciliary transition zone);GO:0043231(intracellular membrane-bounded organelle);GO:0051726(regulation of cell cycle);GO:0070062(extracellular exosome);GO:1902017(regulation of cilium assembly)","NA","K08824","EC:2.7.11.22","cyclin dependent kinase like 1 [Source:HGNC Symbol;Acc:HGNC:1781]",{"v":0.060166,"d":"0.06"},{"v":0.094101,"d":"0.09"},{"v":0.127271,"d":"0.13"},{"v":0.266217,"d":"0.27"},{"v":0.558007,"d":"0.56"},{"v":0.389459,"d":"0.39"},{"v":0.231969962502564,"d":"0.23"},{"v":-2.10799009019901,"d":"-2.11"},1,1,"down","no"]
[138417,0,"chr3","+",38496485,38524060,"ENST00000450732",7,710,"ENSG00000157036","EXOG","GO:0000014(single-stranded DNA endodeoxyribonuclease activity);GO:0000737(DNA catabolic process, endonucleolytic);GO:0003676(nucleic acid binding);GO:0004518(nuclease activity);GO:0004519(endonuclease activity);GO:0004521(endoribonuclease activity);GO:0004529(exodeoxyribonuclease activity);GO:0005739(mitochondrion);GO:0005743(mitochondrial inner membrane);GO:0006309(apoptotic DNA fragmentation);GO:0008150(biological_process);GO:0008409(5'-3' exonuclease activity);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016787(hydrolase activity);GO:0032991(protein-containing complex);GO:0046872(metal ion binding);GO:0090502(RNA phosphodiester bond hydrolysis, endonucleolytic)","NA","K15050","NA","exo/endonuclease G [Source:HGNC Symbol;Acc:HGNC:3347]",0,0,{"v":0.018886,"d":"0.02"},0,0,{"v":0.007701,"d":"0.01"},{"v":2.45240877808077,"d":"2.45"},{"v":1.2941994737093,"d":"1.29"},1,1,"up","no"]
[203503,0,"chrX","-",53412900,53422017,"ENST00000428014",5,868,"ENSG00000072501","SMC1A","GO:0000070(mitotic sister chromatid segregation);GO:0000166(nucleotide binding);GO:0000775(chromosome, centromeric region);GO:0000776(kinetochore);GO:0000777(condensed chromosome kinetochore);GO:0000794(condensed nuclear chromosome);GO:0003682(chromatin binding);GO:0003723(RNA binding);GO:0005515(protein binding);GO:0005524(ATP binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005694(chromosome);GO:0005829(cytosol);GO:0006281(DNA repair);GO:0006974(cellular response to DNA damage stimulus);GO:0007049(cell cycle);GO:0007062(sister chromatid cohesion);GO:0007064(mitotic sister chromatid cohesion);GO:0008278(cohesin complex);GO:0009314(response to radiation);GO:0016363(nuclear matrix);GO:0019827(stem cell population maintenance);GO:0030893(meiotic cohesin complex);GO:0032876(negative regulation of DNA endoreduplication);GO:0036033(mediator complex binding);GO:0046982(protein heterodimerization activity);GO:0051276(chromosome organization);GO:0051301(cell division);GO:0051321(meiotic cell cycle);GO:0072423(response to DNA damage checkpoint signaling);GO:0097431(mitotic spindle pole);GO:1901673(regulation of mitotic spindle assembly)","04110(Cell cycle);04114(Oocyte meiosis)","K06636","NA","structural maintenance of chromosomes 1A [Source:HGNC Symbol;Acc:HGNC:11111]",{"v":0.063014,"d":"0.06"},0,{"v":0.013172,"d":"0.01"},{"v":0.025309,"d":"0.03"},0,0,{"v":3.01023351376981,"d":"3.01"},{"v":1.58987540595193,"d":"1.59"},1,1,"up","no"]
[138405,0,"chr3","+",38496272,38524868,"ENST00000436414",7,1679,"ENSG00000157036","EXOG","GO:0000014(single-stranded DNA endodeoxyribonuclease activity);GO:0000737(DNA catabolic process, endonucleolytic);GO:0003676(nucleic acid binding);GO:0004518(nuclease activity);GO:0004519(endonuclease activity);GO:0004521(endoribonuclease activity);GO:0004529(exodeoxyribonuclease activity);GO:0005739(mitochondrion);GO:0005743(mitochondrial inner membrane);GO:0006309(apoptotic DNA fragmentation);GO:0008150(biological_process);GO:0008409(5'-3' exonuclease activity);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016787(hydrolase activity);GO:0032991(protein-containing complex);GO:0046872(metal ion binding);GO:0090502(RNA phosphodiester bond hydrolysis, endonucleolytic)","NA","K15050","NA","exo/endonuclease G [Source:HGNC Symbol;Acc:HGNC:3347]",0,0,0,0,0,{"v":0.016232,"d":"0.02"},"-inf","-inf",1,1,"down","no"]
[73337,0,"chr16","+",29075022,29104162,"ENST00000566038",15,1611,"ENSG00000284671","AC009093","NA","NA","NA","NA","RRN3 RNA polymerase I transcription factor homolog (S. cerevisiae) (RRN3) pseudogene",0,{"v":0.195193,"d":"0.20"},0,{"v":0.155604,"d":"0.16"},0,{"v":0.057071,"d":"0.06"},{"v":0.917799459268837,"d":"0.92"},{"v":-0.123749138115818,"d":"-0.12"},1,1,"down","no"]
[1586,0,"chr1","-",11650737,11653529,"ENST00000475961",2,237,"ENSG00000116661","FBXO2","GO:0000209(protein polyubiquitination);GO:0001540(amyloid-beta binding);GO:0004842(ubiquitin-protein transferase activity);GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0005783(endoplasmic reticulum);GO:0005829(cytosol);GO:0006464(cellular protein modification process);GO:0006508(proteolysis);GO:0006511(ubiquitin-dependent protein catabolic process);GO:0006516(glycoprotein catabolic process);GO:0008285(negative regulation of cell population proliferation);GO:0016020(membrane);GO:0016567(protein ubiquitination);GO:0019005(SCF ubiquitin ligase complex);GO:0030246(carbohydrate binding);GO:0030433(ubiquitin-dependent ERAD pathway);GO:0031090(organelle membrane);GO:0031146(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process);GO:0031396(regulation of protein ubiquitination);GO:0043197(dendritic spine);GO:0043231(intracellular membrane-bounded organelle);GO:0043687(post-translational protein modification)","04120(Ubiquitin mediated proteolysis);04141(Protein processing in endoplasmic reticulum)","K10099","NA","F-box protein 2 [Source:HGNC Symbol;Acc:HGNC:13581]",0,0,0,0,0,0,1,0,1,1,"no","no"]
[115453,0,"chr2","+",97674502,97702816,"ENST00000627137",8,814,"ENSG00000228486","C2orf92","GO:0016020(membrane);GO:0016021(integral component of membrane)","NA","NA","NA","chromosome 2 open reading frame 92 [Source:HGNC Symbol;Acc:HGNC:49272]",0,0,0,0,0,0,1,0,1,1,"no","no"]
[121053,0,"chr2","-",202206650,202238594,"ENST00000409368",6,1187,"ENSG00000116030","SUMO1","GO:0000122(negative regulation of transcription by RNA polymerase II);GO:0001222(transcription corepressor binding);GO:0001741(XY body);GO:0003723(RNA binding);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005635(nuclear envelope);GO:0005643(nuclear pore);GO:0005654(nucleoplasm);GO:0005730(nucleolus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0006281(DNA repair);GO:0006303(double-strand break repair via nonhomologous end joining);GO:0006355(regulation of transcription, DNA-templated);GO:0008022(protein C-terminus binding);GO:0008076(voltage-gated potassium channel complex);GO:0008134(transcription factor binding);GO:0015459(potassium channel regulator activity);GO:0016020(membrane);GO:0016032(viral process);GO:0016604(nuclear body);GO:0016605(PML body);GO:0016607(nuclear speck);GO:0016925(protein sumoylation);GO:0019899(enzyme binding);GO:0030578(PML body organization);GO:0030674(protein binding, bridging);GO:0031334(positive regulation of protein complex assembly);GO:0031386(protein tag);GO:0031510(SUMO activating enzyme complex);GO:0031625(ubiquitin protein ligase binding);GO:0031647(regulation of protein stability);GO:0031965(nuclear membrane);GO:0032436(positive regulation of proteasomal ubiquitin-dependent protein catabolic process);GO:0032880(regulation of protein localization);GO:0034605(cellular response to heat);GO:0035259(glucocorticoid receptor binding);GO:0043392(negative regulation of DNA binding);GO:0043433(negative regulation of DNA-binding transcription factor activity);GO:0044388(small protein activating enzyme binding);GO:0044389(ubiquitin-like protein ligase binding);GO:0045759(negative regulation of action potential);GO:0045892(negative regulation of transcription, DNA-templated);GO:0050821(protein stabilization);GO:0060021(roof of mouth development);GO:0060334(regulation of interferon-gamma-mediated signaling pathway);GO:0071276(cellular response to cadmium ion);GO:0086004(regulation of cardiac muscle cell contraction);GO:0090204(protein localization to nuclear pore);GO:0097165(nuclear stress granule);GO:1901896(positive regulation of calcium-transporting ATPase activity);GO:1902260(negative regulation of delayed rectifier potassium channel activity);GO:1903169(regulation of calcium ion transmembrane transport)","03013(RNA transport);05418(Fluid shear stress and atherosclerosis)","K12160","NA","small ubiquitin-like modifier 1 [Source:HGNC Symbol;Acc:HGNC:12502]",{"v":0.039562,"d":"0.04"},0,0,0,{"v":0.312158,"d":"0.31"},0,{"v":0.126737101083426,"d":"0.13"},{"v":-2.98008917329927,"d":"-2.98"},1,1,"down","no"]
[74844,0,"chr16","+",51176066,51178898,"ENST00000624410",1,2833,"ENSG00000280344","AC009166","NA","NA","NA","NA","TEC",{"v":0.044308,"d":"0.04"},{"v":0.029416,"d":"0.03"},{"v":0.039406,"d":"0.04"},{"v":0.011105,"d":"0.01"},0,{"v":0.023478,"d":"0.02"},{"v":3.27126044588382,"d":"3.27"},{"v":1.70984662613635,"d":"1.71"},1,1,"up","no"]
[186881,0,"chr8","+",17295964,17300131,"ENST00000521162",3,818,"ENSG00000155975","VPS37A","GO:0000813(ESCRT I complex);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005768(endosome);GO:0005813(centrosome);GO:0005829(cytosol);GO:0006612(protein targeting to membrane);GO:0006623(protein targeting to vacuole);GO:0010008(endosome membrane);GO:0015031(protein transport);GO:0016020(membrane);GO:0016197(endosomal transport);GO:0016236(macroautophagy);GO:0019058(viral life cycle);GO:0031902(late endosome membrane);GO:0032509(endosome transport via multivesicular body sorting pathway);GO:0036258(multivesicular body assembly);GO:0039702(viral budding via host ESCRT complex);GO:0043162(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway);GO:0043231(intracellular membrane-bounded organelle);GO:0043657(host cell);GO:0075733(intracellular transport of virus)","04144(Endocytosis)","K12185","NA","VPS37A, ESCRT-I subunit [Source:HGNC Symbol;Acc:HGNC:24928]",0,0,{"v":0.025969,"d":"0.03"},{"v":0.018766,"d":"0.02"},{"v":0.015084,"d":"0.02"},0,{"v":0.767178729689808,"d":"0.77"},{"v":-0.38236537322322,"d":"-0.38"},1,1,"down","no"]
[78184,0,"chr16","+",83809122,83811667,"ENST00000569301",2,551,"ENSG00000230989","HSBP1","GO:0000122(negative regulation of transcription by RNA polymerase II);GO:0003714(transcription corepressor activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005856(cytoskeleton);GO:0006936(muscle contraction);GO:0035987(endodermal cell differentiation);GO:0042802(identical protein binding);GO:0070370(cellular heat acclimation);GO:1900034(regulation of cellular response to heat)","NA","NA","NA","heat shock factor binding protein 1 [Source:HGNC Symbol;Acc:HGNC:5203]",{"v":0.049175,"d":"0.05"},{"v":0.430092,"d":"0.43"},{"v":0.231881,"d":"0.23"},{"v":0.156007,"d":"0.16"},{"v":0.546309,"d":"0.55"},{"v":0.0894,"d":"0.09"},{"v":0.898236236226121,"d":"0.90"},{"v":-0.154833171067329,"d":"-0.15"},1,1,"down","no"]
[195633,0,"chr9","-",35808045,35811074,"ENST00000460836",5,678,"ENSG00000137098","SPAG8","GO:0001669(acrosomal vesicle);GO:0003674(molecular_function);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005819(spindle);GO:0005856(cytoskeleton);GO:0007049(cell cycle);GO:0007283(spermatogenesis);GO:0007338(single fertilization);GO:0008017(microtubule binding);GO:0008150(biological_process);GO:0016020(membrane);GO:0030154(cell differentiation);GO:0031410(cytoplasmic vesicle);GO:0045944(positive regulation of transcription by RNA polymerase II)","NA","NA","NA","sperm associated antigen 8 [Source:HGNC Symbol;Acc:HGNC:14105]",0,0,0,{"v":0.020119,"d":"0.02"},0,{"v":0.068847,"d":"0.07"},"-inf","-inf",1,1,"down","no"]
[121191,0,"chr2","+",203328405,203380273,"ENST00000444584",5,563,"ENSG00000138443","ABI2","GO:0003677(DNA binding);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005856(cytoskeleton);GO:0005912(adherens junction);GO:0007010(cytoskeleton organization);GO:0007399(nervous system development);GO:0008093(cytoskeletal adaptor activity);GO:0008154(actin polymerization or depolymerization);GO:0016032(viral process);GO:0016477(cell migration);GO:0016601(Rac protein signal transduction);GO:0017124(SH3 domain binding);GO:0018108(peptidyl-tyrosine phosphorylation);GO:0019900(kinase binding);GO:0030027(lamellipodium);GO:0030054(cell junction);GO:0030175(filopodium);GO:0030296(protein tyrosine kinase activator activity);GO:0031209(SCAR complex);GO:0031625(ubiquitin protein ligase binding);GO:0032433(filopodium tip);GO:0042995(cell projection);GO:0043197(dendritic spine);GO:0048365(Rac GTPase binding);GO:0061001(regulation of dendritic spine morphogenesis);GO:0070064(proline-rich region binding);GO:0070309(lens fiber cell morphogenesis);GO:2000601(positive regulation of Arp2/3 complex-mediated actin nucleation)","04810(Regulation of actin cytoskeleton)","K05751","NA","abl interactor 2 [Source:HGNC Symbol;Acc:HGNC:24011]",0,0,0,0,{"v":0.059746,"d":"0.06"},0,"-inf","-inf",1,1,"down","no"]
[86896,0,"chr17","-",47120771,47189251,"ENST00000533415",18,2570,"ENSG00000004897","CDC27","GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005680(anaphase-promoting complex);GO:0005737(cytoplasm);GO:0005813(centrosome);GO:0005819(spindle);GO:0005829(cytosol);GO:0005876(spindle microtubule);GO:0006511(ubiquitin-dependent protein catabolic process);GO:0007091(metaphase/anaphase transition of mitotic cell cycle);GO:0008283(cell population proliferation);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016567(protein ubiquitination);GO:0019903(protein phosphatase binding);GO:0031145(anaphase-promoting complex-dependent catabolic process);GO:0051301(cell division);GO:0070979(protein K11-linked ubiquitination);GO:1901990(regulation of mitotic cell cycle phase transition)","04110(Cell cycle);04114(Oocyte meiosis);04120(Ubiquitin mediated proteolysis);04914(Progesterone-mediated oocyte maturation);05166(Human T-cell leukemia virus 1 infection)","NA","NA","cell division cycle 27 [Source:HGNC Symbol;Acc:HGNC:1728]",{"v":0.041737,"d":"0.04"},{"v":0.109213,"d":"0.11"},{"v":0.090648,"d":"0.09"},{"v":0.028009,"d":"0.03"},{"v":0.10046,"d":"0.10"},{"v":0.096214,"d":"0.10"},{"v":1.07528384434959,"d":"1.08"},{"v":0.104717540542645,"d":"0.10"},1,1,"up","no"]
[6894,0,"chr1","+",61914647,61990436,"ENST00000490547",3,387,"ENSG00000132849","PATJ","GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0005813(centrosome);GO:0005815(microtubule organizing center);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0005923(bicellular tight junction);GO:0016020(membrane);GO:0016324(apical plasma membrane);GO:0030054(cell junction);GO:0032991(protein-containing complex);GO:0035556(intracellular signal transduction);GO:0045177(apical part of cell);GO:0048471(perinuclear region of cytoplasm);GO:0070062(extracellular exosome);GO:0070830(bicellular tight junction assembly)","04390(Hippo signaling pathway);04530(Tight junction);05165(Human papillomavirus infection)","K06092","NA","PATJ, crumbs cell polarity complex component [Source:HGNC Symbol;Acc:HGNC:28881]",{"v":0.054518,"d":"0.05"},{"v":0.079127,"d":"0.08"},{"v":0.077729,"d":"0.08"},{"v":0.055434,"d":"0.06"},0,{"v":0.060554,"d":"0.06"},{"v":1.8223781770528,"d":"1.82"},{"v":0.865822376013901,"d":"0.87"},1,1,"up","no"]
[1467,0,"chr1","-",10461643,10472479,"ENST00000476658",5,744,"ENSG00000160049","DFFA","GO:0000790(nuclear chromatin);GO:0005515(protein binding);GO:0005622(intracellular);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0005811(lipid droplet);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0006309(apoptotic DNA fragmentation);GO:0006915(apoptotic process);GO:0007165(signal transduction);GO:0019904(protein domain specific binding);GO:0032076(negative regulation of deoxyribonuclease activity);GO:0043065(positive regulation of apoptotic process);GO:0044183(protein folding chaperone);GO:0060703(deoxyribonuclease inhibitor activity);GO:0061077(chaperone-mediated protein folding);GO:0070242(thymocyte apoptotic process);GO:1900118(negative regulation of execution phase of apoptosis);GO:1902511(negative regulation of apoptotic DNA fragmentation)","04210(Apoptosis)","K02310","NA","DNA fragmentation factor subunit alpha [Source:HGNC Symbol;Acc:HGNC:2772]",0,{"v":0.099575,"d":"0.10"},{"v":0.000252,"d":"0.00"},{"v":0.047953,"d":"0.05"},0,{"v":0.062288,"d":"0.06"},{"v":0.905534238622654,"d":"0.91"},{"v":-0.14315890378673,"d":"-0.14"},1,1,"down","no"]
[47500,0,"chr12","+",106955844,106971246,"ENST00000551489",5,621,"ENSG00000151135","TMEM263","GO:0016020(membrane);GO:0016021(integral component of membrane)","NA","NA","NA","transmembrane protein 263 [Source:HGNC Symbol;Acc:HGNC:28281]",{"v":0.474947,"d":"0.47"},{"v":0.569869,"d":"0.57"},{"v":1.125713,"d":"1.13"},{"v":0.375749,"d":"0.38"},{"v":0.388511,"d":"0.39"},{"v":1.079363,"d":"1.08"},{"v":1.17731716299916,"d":"1.18"},{"v":0.235503027128362,"d":"0.24"},1,1,"up","no"]
[56657,0,"chr14","+",52553288,52636725,"ENST00000542169",8,2808,"ENSG00000180998","GPR137C","GO:0016020(membrane);GO:0016021(integral component of membrane)","NA","K22989","NA","G protein-coupled receptor 137C [Source:HGNC Symbol;Acc:HGNC:25445]",0,0,0,0,0,{"v":0.131388,"d":"0.13"},"-inf","-inf",1,1,"down","no"]
[70119,0,"chr16","+",2205481,2208492,"ENST00000561651",7,703,"ENSG00000167965","MLST8","GO:0005515(protein binding);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0007050(cell cycle arrest);GO:0016241(regulation of macroautophagy);GO:0031929(TOR signaling);GO:0031931(TORC1 complex);GO:0031932(TORC2 complex);GO:0032008(positive regulation of TOR signaling);GO:0032148(activation of protein kinase B activity);GO:0032956(regulation of actin cytoskeleton organization);GO:0038202(TORC1 signaling);GO:0043539(protein serine/threonine kinase activator activity);GO:0071902(positive regulation of protein serine/threonine kinase activity);GO:1900034(regulation of cellular response to heat)","04136(Autophagy - other);04140(Autophagy - animal);04150(mTOR signaling pathway);04151(PI3K-Akt signaling pathway);04714(Thermogenesis)","K08266","NA","MTOR associated protein, LST8 homolog [Source:HGNC Symbol;Acc:HGNC:24825]",{"v":0.002275,"d":"0.00"},{"v":0.004069,"d":"0.00"},{"v":0.027542,"d":"0.03"},{"v":0.011715,"d":"0.01"},{"v":0.006775,"d":"0.01"},{"v":0.002498,"d":"0.00"},{"v":1.61454164284353,"d":"1.61"},{"v":0.691124651945431,"d":"0.69"},1,1,"up","no"]
[42031,0,"chr12","-",47701191,47705999,"ENST00000551293",3,621,"ENSG00000005175","RPAP3","GO:0005515(protein binding);GO:0005829(cytosol);GO:0097255(R2TP complex)","NA","K23002","NA","RNA polymerase II associated protein 3 [Source:HGNC Symbol;Acc:HGNC:26151]",{"v":0.012836,"d":"0.01"},{"v":0.303767,"d":"0.30"},{"v":0.211412,"d":"0.21"},{"v":0.409592,"d":"0.41"},{"v":0.008273,"d":"0.01"},{"v":0.173008,"d":"0.17"},{"v":0.893618425617688,"d":"0.89"},{"v":-0.162269161669976,"d":"-0.16"},1,1,"down","no"]
[77160,0,"chr16","+",70579895,70660682,"ENST00000429149",7,1779,"ENSG00000157368","IL34","GO:0001934(positive regulation of protein phosphorylation);GO:0002376(immune system process);GO:0005125(cytokine activity);GO:0005157(macrophage colony-stimulating factor receptor binding);GO:0005576(extracellular region);GO:0005615(extracellular space);GO:0006954(inflammatory response);GO:0008083(growth factor activity);GO:0008284(positive regulation of cell population proliferation);GO:0010469(regulation of signaling receptor activity);GO:0019221(cytokine-mediated signaling pathway);GO:0045087(innate immune response);GO:0045651(positive regulation of macrophage differentiation);GO:0045657(positive regulation of monocyte differentiation);GO:0048714(positive regulation of oligodendrocyte differentiation);GO:0061518(microglial cell proliferation)","04060(Cytokine-cytokine receptor interaction)","K22633","NA","interleukin 34 [Source:HGNC Symbol;Acc:HGNC:28529]",{"v":0.034736,"d":"0.03"},{"v":0.07316,"d":"0.07"},{"v":0.003856,"d":"0.00"},0,{"v":0.157368,"d":"0.16"},{"v":0.099082,"d":"0.10"},{"v":0.43576525638526,"d":"0.44"},{"v":-1.19837692009221,"d":"-1.20"},1,1,"down","no"]
[68212,0,"chr15","+",90483205,90486051,"ENST00000560218",3,544,"ENSG00000140575","IQGAP1","GO:0001726(ruffle);GO:0001817(regulation of cytokine production);GO:0005095(GTPase inhibitor activity);GO:0005096(GTPase activator activity);GO:0005509(calcium ion binding);GO:0005515(protein binding);GO:0005516(calmodulin binding);GO:0005547(phosphatidylinositol-3,4,5-trisphosphate binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005874(microtubule);GO:0005884(actin filament);GO:0005886(plasma membrane);GO:0005911(cell-cell junction);GO:0005925(focal adhesion);GO:0007165(signal transduction);GO:0007173(epidermal growth factor receptor signaling pathway);GO:0007346(regulation of mitotic cell cycle);GO:0008543(fibroblast growth factor receptor signaling pathway);GO:0015629(actin cytoskeleton);GO:0015630(microtubule cytoskeleton);GO:0016020(membrane);GO:0016032(viral process);GO:0016328(lateral plasma membrane);GO:0016477(cell migration);GO:0017048(Rho GTPase binding);GO:0019901(protein kinase binding);GO:0019903(protein phosphatase binding);GO:0019904(protein domain specific binding);GO:0030424(axon);GO:0030426(growth cone);GO:0030496(midbody);GO:0030667(secretory granule membrane);GO:0031234(extrinsic component of cytoplasmic side of plasma membrane);GO:0031252(cell leading edge);GO:0031267(small GTPase binding);GO:0032947(protein-containing complex scaffold activity);GO:0032991(protein-containing complex);GO:0034260(negative regulation of GTPase activity);GO:0035305(negative regulation of dephosphorylation);GO:0036057(slit diaphragm);GO:0036120(cellular response to platelet-derived growth factor stimulus);GO:0036464(cytoplasmic ribonucleoprotein granule);GO:0043005(neuron projection);GO:0043087(regulation of GTPase activity);GO:0043312(neutrophil degranulation);GO:0043406(positive regulation of MAP kinase activity);GO:0043539(protein serine/threonine kinase activator activity);GO:0043547(positive regulation of GTPase activity);GO:0044344(cellular response to fibroblast growth factor stimulus);GO:0044548(S100 protein binding);GO:0044877(protein-containing complex binding);GO:0045121(membrane raft);GO:0045296(cadherin binding);GO:0045860(positive regulation of protein kinase activity);GO:0048008(platelet-derived growth factor receptor signaling pathway);GO:0048365(Rac GTPase binding);GO:0051019(mitogen-activated protein kinase binding);GO:0051894(positive regulation of focal adhesion assembly);GO:0070062(extracellular exosome);GO:0071277(cellular response to calcium ion);GO:0071364(cellular response to epidermal growth factor stimulus);GO:0072015(glomerular visceral epithelial cell development);GO:1900006(positive regulation of dendrite development);GO:1900086(positive regulation of peptidyl-tyrosine autophosphorylation);GO:1903829(positive regulation of cellular protein localization);GO:1904754(positive regulation of vascular associated smooth muscle cell migration);GO:1990138(neuron projection extension);GO:1990776(response to angiotensin);GO:1990904(ribonucleoprotein complex)","04520(Adherens junction);04810(Regulation of actin cytoskeleton);05205(Proteoglycans in cancer)","K16848","NA","IQ motif containing GTPase activating protein 1 [Source:HGNC Symbol;Acc:HGNC:6110]",{"v":0.067594,"d":"0.07"},{"v":0.028013,"d":"0.03"},{"v":0.030172,"d":"0.03"},{"v":0.066362,"d":"0.07"},{"v":0.022765,"d":"0.02"},{"v":0.028673,"d":"0.03"},{"v":1.06773344651952,"d":"1.07"},{"v":0.0945515314997799,"d":"0.09"},1,1,"up","no"]
[68130,0,"chr15","+",90002486,90067374,"ENST00000559419",2,332,"ENSG00000140548","ZNF710","GO:0000981(DNA-binding transcription factor activity, RNA polymerase II-specific);GO:0003676(nucleic acid binding);GO:0003677(DNA binding);GO:0005634(nucleus);GO:0006357(regulation of transcription by RNA polymerase II);GO:0046872(metal ion binding)","NA","NA","NA","zinc finger protein 710 [Source:HGNC Symbol;Acc:HGNC:25352]",0,0,0,0,0,0,1,0,1,1,"no","no"]
[88883,0,"chr17","-",63702835,63741761,"ENST00000245865",10,2959,"ENSG00000266173","STRADA","GO:0000165(MAPK cascade);GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005515(protein binding);GO:0005524(ATP binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0006468(protein phosphorylation);GO:0006611(protein export from nucleus);GO:0007049(cell cycle);GO:0007050(cell cycle arrest);GO:0019900(kinase binding);GO:0023014(signal transduction by protein phosphorylation);GO:0030295(protein kinase activator activity);GO:0031098(stress-activated protein kinase signaling cascade);GO:0032147(activation of protein kinase activity);GO:0043539(protein serine/threonine kinase activator activity);GO:0048812(neuron projection morphogenesis);GO:0071902(positive regulation of protein serine/threonine kinase activity)","04150(mTOR signaling pathway);04152(AMPK signaling pathway)","K08271","NA","STE20 related adaptor alpha [Source:HGNC Symbol;Acc:HGNC:30172]",0,0,{"v":0.1463,"d":"0.15"},0,0,0,"inf","inf",1,1,"up","no"]
[107593,0,"chr19","-",53164266,53193374,"ENST00000650736",5,2461,"ENSG00000197497","ZNF665","GO:0000981(DNA-binding transcription factor activity, RNA polymerase II-specific);GO:0003676(nucleic acid binding);GO:0003677(DNA binding);GO:0005622(intracellular);GO:0005634(nucleus);GO:0006355(regulation of transcription, DNA-templated);GO:0006357(regulation of transcription by RNA polymerase II);GO:0046872(metal ion binding)","05168(Herpes simplex virus 1 infection)","K09228","NA","zinc finger protein 665 [Source:HGNC Symbol;Acc:HGNC:25885]",{"v":0.007066,"d":"0.01"},0,0,{"v":0.005897,"d":"0.01"},0,0,{"v":1.19823639138545,"d":"1.20"},{"v":0.260912555068737,"d":"0.26"},1,1,"up","no"]
[3896,0,"chr1","-",32205498,32206814,"ENST00000421616",4,786,"ENSG00000224066","AL049795","NA","NA","NA","NA","novel transcript",{"v":0.18968,"d":"0.19"},{"v":0.138883,"d":"0.14"},{"v":0.186074,"d":"0.19"},{"v":0.22355,"d":"0.22"},{"v":0.043369,"d":"0.04"},{"v":0.200477,"d":"0.20"},{"v":1.10107275201328,"d":"1.10"},{"v":0.138909796332967,"d":"0.14"},1,1,"up","no"]
[174593,0,"chr6","+",143496303,143503996,"ENST00000438118",3,987,"ENSG00000229036","VDAC1P8","NA","NA","NA","NA","voltage dependent anion channel 1 pseudogene 8 [Source:HGNC Symbol;Acc:HGNC:37483]",0,0,0,{"v":0.099593,"d":"0.10"},0,0,"-inf","-inf",1,1,"down","no"]
[19929,0,"chr10","-",27123547,27154392,"ENST00000491542",7,912,"ENSG00000136758","YME1L1","GO:0000166(nucleotide binding);GO:0004176(ATP-dependent peptidase activity);GO:0004222(metalloendopeptidase activity);GO:0005515(protein binding);GO:0005524(ATP binding);GO:0005739(mitochondrion);GO:0005743(mitochondrial inner membrane);GO:0006508(proteolysis);GO:0006515(protein quality control for misfolded or incompletely synthesized proteins);GO:0006851(mitochondrial calcium ion transmembrane transport);GO:0007005(mitochondrion organization);GO:0008233(peptidase activity);GO:0008237(metallopeptidase activity);GO:0008283(cell population proliferation);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016604(nuclear body);GO:0016787(hydrolase activity);GO:0034214(protein hexamerization);GO:0034982(mitochondrial protein processing);GO:0035694(mitochondrial protein catabolic process);GO:0043066(negative regulation of apoptotic process);GO:0046872(metal ion binding)","NA","K08955","EC:3.4.24.-","YME1 like 1 ATPase [Source:HGNC Symbol;Acc:HGNC:12843]",0,0,0,{"v":0.293491,"d":"0.29"},0,0,"-inf","-inf",1,1,"down","no"]
[113285,0,"chr2","-",69396115,69437435,"ENST00000471185",6,598,"ENSG00000169599","NFU1","GO:0005506(iron ion binding);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0005739(mitochondrion);GO:0005829(cytosol);GO:0016226(iron-sulfur cluster assembly);GO:0046872(metal ion binding);GO:0051536(iron-sulfur cluster binding);GO:0051539(4 iron, 4 sulfur cluster binding);GO:0097428(protein maturation by iron-sulfur cluster transfer)","NA","K22074","NA","NFU1 iron-sulfur cluster scaffold [Source:HGNC Symbol;Acc:HGNC:16287]",{"v":0.694431,"d":"0.69"},{"v":0.533378,"d":"0.53"},{"v":0.454969,"d":"0.45"},{"v":0.61228,"d":"0.61"},{"v":0.400396,"d":"0.40"},{"v":0.086117,"d":"0.09"},{"v":1.53147863155299,"d":"1.53"},{"v":0.614925237411825,"d":"0.61"},1,1,"up","no"]
[124162,0,"chr2","-",241500047,241501698,"ENST00000496159",3,463,"ENSG00000115694","STK25","GO:0000139(Golgi membrane);GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005515(protein binding);GO:0005524(ATP binding);GO:0005737(cytoplasm);GO:0005794(Golgi apparatus);GO:0006468(protein phosphorylation);GO:0006979(response to oxidative stress);GO:0007163(establishment or maintenance of cell polarity);GO:0007165(signal transduction);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0016740(transferase activity);GO:0023014(signal transduction by protein phosphorylation);GO:0031098(stress-activated protein kinase signaling cascade);GO:0032147(activation of protein kinase activity);GO:0032874(positive regulation of stress-activated MAPK cascade);GO:0036481(intrinsic apoptotic signaling pathway in response to hydrogen peroxide);GO:0042542(response to hydrogen peroxide);GO:0042803(protein homodimerization activity);GO:0046777(protein autophosphorylation);GO:0046872(metal ion binding);GO:0050772(positive regulation of axonogenesis);GO:0051645(Golgi localization);GO:0051683(establishment of Golgi localization);GO:0070062(extracellular exosome);GO:0090168(Golgi reassembly)","NA","K08838","EC:2.7.11.1","serine/threonine kinase 25 [Source:HGNC Symbol;Acc:HGNC:11404]",{"v":0.876874,"d":"0.88"},{"v":0.369415,"d":"0.37"},{"v":0.766948,"d":"0.77"},{"v":0.403471,"d":"0.40"},{"v":0.296245,"d":"0.30"},{"v":1.123218,"d":"1.12"},{"v":1.10439379593556,"d":"1.10"},{"v":0.143254688549181,"d":"0.14"},1,1,"up","no"]
[60673,0,"chr14","+",102875687,102905463,"ENST00000559734",6,870,"ENSG00000131323","TRAF3","GO:0001817(regulation of cytokine production);GO:0002224(toll-like receptor signaling pathway);GO:0002376(immune system process);GO:0004842(ubiquitin-protein transferase activity);GO:0005164(tumor necrosis factor receptor binding);GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0005739(mitochondrion);GO:0005768(endosome);GO:0005829(cytosol);GO:0006915(apoptotic process);GO:0007165(signal transduction);GO:0008063(Toll signaling pathway);GO:0008270(zinc ion binding);GO:0009898(cytoplasmic side of plasma membrane);GO:0016567(protein ubiquitination);GO:0016579(protein deubiquitination);GO:0016740(transferase activity);GO:0019901(protein kinase binding);GO:0019903(protein phosphatase binding);GO:0030162(regulation of proteolysis);GO:0031625(ubiquitin protein ligase binding);GO:0031996(thioesterase binding);GO:0032088(negative regulation of NF-kappaB transcription factor activity);GO:0032648(regulation of interferon-beta production);GO:0032991(protein-containing complex);GO:0033209(tumor necrosis factor-mediated signaling pathway);GO:0035631(CD40 receptor complex);GO:0035666(TRIF-dependent toll-like receptor signaling pathway);GO:0042981(regulation of apoptotic process);GO:0045087(innate immune response);GO:0046872(metal ion binding);GO:0050688(regulation of defense response to virus)","04064(NF-kappa B signaling pathway);04620(Toll-like receptor signaling pathway);04621(NOD-like receptor signaling pathway);04622(RIG-I-like receptor signaling pathway);04657(IL-17 signaling pathway);04668(TNF signaling pathway);05160(Hepatitis C);05161(Hepatitis B);05162(Measles);05165(Human papillomavirus infection);05167(Kaposi sarcoma-associated herpesvirus infection);05168(Herpes simplex virus 1 infection);05169(Epstein-Barr virus infection);05200(Pathways in cancer);05203(Viral carcinogenesis);05222(Small cell lung cancer)","K03174","NA","TNF receptor associated factor 3 [Source:HGNC Symbol;Acc:HGNC:12033]",0,0,0,0,0,0,1,0,1,1,"no","no"]
[32886,0,"chr11","-",66686793,66687524,"ENST00000530775",2,473,"ENSG00000173898","SPTBN2","GO:0000165(MAPK cascade);GO:0003779(actin binding);GO:0005200(structural constituent of cytoskeleton);GO:0005515(protein binding);GO:0005543(phospholipid binding);GO:0005615(extracellular space);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005856(cytoskeleton);GO:0005938(cell cortex);GO:0006888(endoplasmic reticulum to Golgi vesicle-mediated transport);GO:0007010(cytoskeleton organization);GO:0007411(axon guidance);GO:0007416(synapse assembly);GO:0008091(spectrin);GO:0016192(vesicle-mediated transport);GO:0016324(apical plasma membrane);GO:0019886(antigen processing and presentation of exogenous peptide antigen via MHC class II);GO:0021692(cerebellar Purkinje cell layer morphogenesis);GO:0030054(cell junction);GO:0030534(adult behavior);GO:0035264(multicellular organism growth);GO:0043025(neuronal cell body);GO:0045296(cadherin binding);GO:0051693(actin filament capping);GO:0098688(parallel fiber to Purkinje cell synapse);GO:0098793(presynapse);GO:0098918(structural constituent of synapse);GO:0098978(glutamatergic synapse);GO:0099173(postsynapse organization);GO:0099189(postsynaptic spectrin-associated cytoskeleton)","NA","K06115","NA","spectrin beta, non-erythrocytic 2 [Source:HGNC Symbol;Acc:HGNC:11276]",0,{"v":0.076348,"d":"0.08"},0,0,0,{"v":0.046259,"d":"0.05"},{"v":1.65044639961953,"d":"1.65"},{"v":0.722856285934727,"d":"0.72"},1,1,"up","no"]
[201404,0,"chrX","+",9531006,9719723,"ENST00000646640",18,7061,"ENSG00000101849","TBL1X","GO:0000118(histone deacetylase complex);GO:0000122(negative regulation of transcription by RNA polymerase II);GO:0003714(transcription corepressor activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0006357(regulation of transcription by RNA polymerase II);GO:0006508(proteolysis);GO:0007605(sensory perception of sound);GO:0008013(beta-catenin binding);GO:0008022(protein C-terminus binding);GO:0008134(transcription factor binding);GO:0016575(histone deacetylation);GO:0017053(transcriptional repressor complex);GO:0019216(regulation of lipid metabolic process);GO:0019904(protein domain specific binding);GO:0042393(histone binding);GO:0043161(proteasome-mediated ubiquitin-dependent protein catabolic process);GO:0044212(transcription regulatory region DNA binding);GO:0045893(positive regulation of transcription, DNA-templated);GO:0045944(positive regulation of transcription by RNA polymerase II);GO:0050821(protein stabilization);GO:0072686(mitotic spindle);GO:0090263(positive regulation of canonical Wnt signaling pathway)","04310(Wnt signaling pathway)","K04508","NA","transducin beta like 1 X-linked [Source:HGNC Symbol;Acc:HGNC:11585]",0,0,0,0,0,0,1,0,1,1,"no","no"]
[137536,0,"chr3","-",19879472,19934217,"ENST00000295824",13,2860,"ENSG00000163576","EFHB","GO:0005509(calcium ion binding);GO:0046872(metal ion binding)","NA","NA","NA","EF-hand domain family member B [Source:HGNC Symbol;Acc:HGNC:26330]",{"v":0.057999,"d":"0.06"},{"v":0.022972,"d":"0.02"},0,{"v":0.037873,"d":"0.04"},{"v":0.027079,"d":"0.03"},0,{"v":1.24662827934475,"d":"1.25"},{"v":0.318031345286168,"d":"0.32"},1,1,"up","no"]
[130403,0,"chr21","+",38809636,38818646,"ENST00000456966",7,972,"ENSG00000157557","ETS2","GO:0000122(negative regulation of transcription by RNA polymerase II);GO:0000977(RNA polymerase II regulatory region sequence-specific DNA binding);GO:0000978(RNA polymerase II proximal promoter sequence-specific DNA binding);GO:0000981(DNA-binding transcription factor activity, RNA polymerase II-specific);GO:0001227(DNA-binding transcription repressor activity, RNA polymerase II-specific);GO:0001501(skeletal system development);GO:0001712(ectodermal cell fate commitment);GO:0003677(DNA binding);GO:0003700(DNA-binding transcription factor activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0006355(regulation of transcription, DNA-templated);GO:0006357(regulation of transcription by RNA polymerase II);GO:0007498(mesoderm development);GO:0019904(protein domain specific binding);GO:0030154(cell differentiation);GO:0035259(glucocorticoid receptor binding);GO:0043565(sequence-specific DNA binding);GO:0045893(positive regulation of transcription, DNA-templated);GO:0045944(positive regulation of transcription by RNA polymerase II);GO:0090009(primitive streak formation)","04014(Ras signaling pathway);05166(Human T-cell leukemia virus 1 infection)","K21932","NA","ETS proto-oncogene 2, transcription factor [Source:HGNC Symbol;Acc:HGNC:3489]",{"v":0.068864,"d":"0.07"},{"v":0.059997,"d":"0.06"},{"v":0.026874,"d":"0.03"},{"v":0.042729,"d":"0.04"},{"v":0.026686,"d":"0.03"},0,{"v":2.24353525894979,"d":"2.24"},{"v":1.1657738572981,"d":"1.17"},1,1,"up","no"]
[177283,0,"chr7","+",23299339,23307990,"ENST00000287543",3,572,"ENSG00000156928","MALSU1","GO:0005515(protein binding);GO:0005739(mitochondrion);GO:0005759(mitochondrial matrix);GO:0005762(mitochondrial large ribosomal subunit);GO:0005829(cytosol);GO:0017148(negative regulation of translation);GO:0042254(ribosome biogenesis);GO:0042273(ribosomal large subunit biogenesis);GO:0043023(ribosomal large subunit binding);GO:0070130(negative regulation of mitochondrial translation);GO:0090071(negative regulation of ribosome biogenesis)","NA","NA","NA","mitochondrial assembly of ribosomal large subunit 1 [Source:HGNC Symbol;Acc:HGNC:21721]",{"v":0.283825,"d":"0.28"},{"v":0.531838,"d":"0.53"},{"v":0.103552,"d":"0.10"},{"v":0.15921,"d":"0.16"},{"v":0.135209,"d":"0.14"},{"v":0.219717,"d":"0.22"},{"v":1.78788297259869,"d":"1.79"},{"v":0.838252306780173,"d":"0.84"},1,1,"up","no"]
[11358,0,"chr1","+",151841877,151850385,"ENST00000434182",3,506,"ENSG00000234614","C2CD4D-AS1","NA","NA","NA","NA","C2CD4D and THEM5 antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:54045]",{"v":0.17484,"d":"0.17"},{"v":0.209721,"d":"0.21"},0,{"v":0.394778,"d":"0.39"},{"v":0.25558,"d":"0.26"},0,{"v":0.591306634192245,"d":"0.59"},{"v":-0.758021631309989,"d":"-0.76"},1,1,"down","no"]
[112899,0,"chr2","-",62561058,62561423,"ENST00000445584",1,366,"ENSG00000230595","RSL24D1P2","NA","NA","NA","NA","ribosomal L24 domain containing 1 pseudogene 2 [Source:HGNC Symbol;Acc:HGNC:37867]",0,0,0,0,{"v":0.035435,"d":"0.04"},0,"-inf","-inf",1,1,"down","no"]
[124783,0,"chr20","+",4148779,4187746,"ENST00000621355",8,2322,"ENSG00000088826","SMOX","GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0006596(polyamine biosynthetic process);GO:0006598(polyamine catabolic process);GO:0016491(oxidoreductase activity);GO:0031965(nuclear membrane);GO:0043231(intracellular membrane-bounded organelle);GO:0046208(spermine catabolic process);GO:0046592(polyamine oxidase activity);GO:0052894(norspermine:oxygen oxidoreductase activity);GO:0052895(N1-acetylspermine:oxygen oxidoreductase (N1-acetylspermidine-forming) activity);GO:0052901(spermine:oxygen oxidoreductase (spermidine-forming) activity);GO:0055114(oxidation-reduction process)","00330(Arginine and proline metabolism);00410(beta-Alanine metabolism)","K12259","1.5.3.-;EC:1.5.3.16","spermine oxidase [Source:HGNC Symbol;Acc:HGNC:15862]",{"v":0.199594,"d":"0.20"},{"v":0.010158,"d":"0.01"},{"v":0.046262,"d":"0.05"},{"v":0.028466,"d":"0.03"},0,{"v":0.048745,"d":"0.05"},{"v":3.31577106888915,"d":"3.32"},{"v":1.7293444021353,"d":"1.73"},1,1,"up","no"]
[122563,0,"chr2","+",221944223,221944612,"ENST00000417147",1,390,"ENSG00000233868","AC009302","NA","NA","NA","NA","chromosome 12 open reading frame 31 (C12orf31) pseudogene",{"v":0.575376,"d":"0.58"},{"v":0.394945,"d":"0.39"},{"v":0.208687,"d":"0.21"},{"v":0.461088,"d":"0.46"},{"v":0.129243,"d":"0.13"},{"v":0.208848,"d":"0.21"},{"v":1.47527399994244,"d":"1.48"},{"v":0.560982928472357,"d":"0.56"},1,1,"up","no"]
[109835,0,"chr2","+",9843482,9868764,"ENST00000402170",7,715,"ENSG00000115750","TAF1B","GO:0001164(RNA polymerase I CORE element sequence-specific DNA binding);GO:0001188(RNA polymerase I preinitiation complex assembly);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005668(RNA polymerase transcription factor SL1 complex);GO:0005730(nucleolus);GO:0006351(transcription, DNA-templated);GO:0006360(transcription by RNA polymerase I);GO:0006361(transcription initiation from RNA polymerase I promoter);GO:0006362(transcription elongation from RNA polymerase I promoter);GO:0006363(termination of RNA polymerase I transcription);GO:0017025(TBP-class protein binding);GO:0042790(nucleolar large rRNA transcription by RNA polymerase I);GO:0045815(positive regulation of gene expression, epigenetic);GO:0046872(metal ion binding);GO:0070860(RNA polymerase I core factor complex)","NA","K15213","NA","TATA-box binding protein associated factor, RNA polymerase I subunit B [Source:HGNC Symbol;Acc:HGNC:11533]",0,{"v":0.308578,"d":"0.31"},0,0,0,0,"inf","inf",1,1,"up","no"]
[190304,0,"chr8","+",78666129,78697505,"ENST00000521176",5,546,"ENSG00000104427","ZC2HC1A","GO:0005515(protein binding);GO:0046872(metal ion binding)","NA","NA","NA","zinc finger C2HC-type containing 1A [Source:HGNC Symbol;Acc:HGNC:24277]",0,0,0,0,0,0,1,0,1,1,"no","no"]
[51488,0,"chr13","+",45341420,45377127,"ENST00000520622",4,604,"ENSG00000170919","TPT1-AS1","NA","NA","NA","NA","TPT1 antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:43686]",0,0,0,0,0,0,1,0,1,1,"no","no"]
[98658,0,"chr19","-",10137888,10140195,"ENST00000587197",3,809,"ENSG00000130816","DNMT1","GO:0000122(negative regulation of transcription by RNA polymerase II);GO:0000792(heterochromatin);GO:0000981(DNA-binding transcription factor activity, RNA polymerase II-specific);GO:0003677(DNA binding);GO:0003682(chromatin binding);GO:0003723(RNA binding);GO:0003886(DNA (cytosine-5-)-methyltransferase activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005657(replication fork);GO:0005721(pericentric heterochromatin);GO:0006306(DNA methylation);GO:0006325(chromatin organization);GO:0007265(Ras protein signal transduction);GO:0008168(methyltransferase activity);GO:0008270(zinc ion binding);GO:0008327(methyl-CpG binding);GO:0009008(DNA-methyltransferase activity);GO:0010216(maintenance of DNA methylation);GO:0010424(DNA methylation on cytosine within a CG sequence);GO:0010468(regulation of gene expression);GO:0010628(positive regulation of gene expression);GO:0010629(negative regulation of gene expression);GO:0016458(gene silencing);GO:0016740(transferase activity);GO:0032259(methylation);GO:0032776(DNA methylation on cytosine);GO:0042127(regulation of cell population proliferation);GO:0043045(DNA methylation involved in embryo development);GO:0045814(negative regulation of gene expression, epigenetic);GO:0045892(negative regulation of transcription, DNA-templated);GO:0046872(metal ion binding);GO:0051571(positive regulation of histone H3-K4 methylation);GO:0051573(negative regulation of histone H3-K9 methylation);GO:0071230(cellular response to amino acid stimulus);GO:0090116(C-5 methylation of cytosine);GO:0090309(positive regulation of methylation-dependent chromatin silencing);GO:1904707(positive regulation of vascular smooth muscle cell proliferation);GO:1905460(negative regulation of vascular associated smooth muscle cell apoptotic process);GO:1905931(negative regulation of vascular smooth muscle cell differentiation involved in phenotypic switching);GO:1990841(promoter-specific chromatin binding)","00270(Cysteine and methionine metabolism);05206(MicroRNAs in cancer)","K00558","EC:2.1.1.37","DNA methyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:2976]",{"v":0.157966,"d":"0.16"},{"v":0.029536,"d":"0.03"},{"v":0.554032,"d":"0.55"},{"v":0.08916,"d":"0.09"},{"v":0.889637,"d":"0.89"},{"v":0.30746,"d":"0.31"},{"v":0.576505317366591,"d":"0.58"},{"v":-0.794594180326822,"d":"-0.79"},1,1,"down","no"]
[43660,0,"chr12","-",54162065,54164452,"ENST00000551732",2,754,"ENSG00000257534","AC023794","NA","NA","NA","NA","novel transcript",{"v":0.047541,"d":"0.05"},{"v":0.123976,"d":"0.12"},{"v":0.080259,"d":"0.08"},{"v":0.049787,"d":"0.05"},{"v":0.042208,"d":"0.04"},0,{"v":2.73684439371705,"d":"2.74"},{"v":1.45251341102932,"d":"1.45"},1,1,"up","no"]
[27215,0,"chr11","+",7992127,7996169,"ENST00000530219",4,2110,"ENSG00000175390","EIF3F","GO:0001732(formation of cytoplasmic translation initiation complex);GO:0002183(cytoplasmic translational initiation);GO:0003743(translation initiation factor activity);GO:0004843(thiol-dependent ubiquitin-specific protease activity);GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005852(eukaryotic translation initiation factor 3 complex);GO:0006412(translation);GO:0006413(translational initiation);GO:0006508(proteolysis);GO:0008233(peptidase activity);GO:0008234(cysteine-type peptidase activity);GO:0016020(membrane);GO:0016282(eukaryotic 43S preinitiation complex);GO:0016579(protein deubiquitination);GO:0016787(hydrolase activity);GO:0031369(translation initiation factor binding);GO:0033290(eukaryotic 48S preinitiation complex);GO:0036459(thiol-dependent ubiquitinyl hydrolase activity);GO:0071541(eukaryotic translation initiation factor 3 complex, eIF3m);GO:0075522(IRES-dependent viral translational initiation)","03013(RNA transport)","K03249","NA","eukaryotic translation initiation factor 3 subunit F [Source:HGNC Symbol;Acc:HGNC:3275]",{"v":0.201078,"d":"0.20"},{"v":0.209223,"d":"0.21"},{"v":0.378864,"d":"0.38"},{"v":0.21341,"d":"0.21"},{"v":0.30536,"d":"0.31"},{"v":0.344686,"d":"0.34"},{"v":0.913960873512953,"d":"0.91"},{"v":-0.129795689775865,"d":"-0.13"},1,1,"down","no"]
[98212,0,"chr19","+",7944241,7945400,"ENST00000652364",2,1073,"ENSG00000286138","AC010336","NA","NA","NA","NA","novel transcript",0,0,0,0,0,0,1,0,1,1,"no","no"]
[3155,0,"chr1","+",26432340,26469226,"ENST00000526219",8,1072,"ENSG00000117682","DHDDS","GO:0002094(polyprenyltransferase activity);GO:0005515(protein binding);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0006486(protein glycosylation);GO:0006489(dolichyl diphosphate biosynthetic process);GO:0006629(lipid metabolic process);GO:0016020(membrane);GO:0016094(polyprenol biosynthetic process);GO:0016740(transferase activity);GO:0016765(transferase activity, transferring alkyl or aryl (other than methyl) groups);GO:0045547(dehydrodolichyl diphosphate synthase activity);GO:1904423(dehydrodolichyl diphosphate synthase complex)","00900(Terpenoid backbone biosynthesis)","K11778","EC:2.5.1.87","dehydrodolichyl diphosphate synthase subunit [Source:HGNC Symbol;Acc:HGNC:20603]",0,0,{"v":0.236972,"d":"0.24"},0,0,0,"inf","inf",1,1,"up","no"]
[49479,0,"chr12","+",123712356,123737502,"ENST00000540368",9,1479,"ENSG00000185344","ATP6V0A2","GO:0000220(vacuolar proton-transporting V-type ATPase, V0 domain);GO:0001669(acrosomal vesicle);GO:0005515(protein binding);GO:0005765(lysosomal membrane);GO:0005768(endosome);GO:0005886(plasma membrane);GO:0006811(ion transport);GO:0006879(cellular iron ion homeostasis);GO:0006955(immune response);GO:0007035(vacuolar acidification);GO:0008286(insulin receptor signaling pathway);GO:0010008(endosome membrane);GO:0015078(proton transmembrane transporter activity);GO:0015991(ATP hydrolysis coupled proton transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016241(regulation of macroautophagy);GO:0016471(vacuolar proton-transporting V-type ATPase complex);GO:0030670(phagocytic vesicle membrane);GO:0033179(proton-transporting V-type ATPase, V0 domain);GO:0033572(transferrin transport);GO:0034220(ion transmembrane transport);GO:0036295(cellular response to increased oxygen levels);GO:0043229(intracellular organelle);GO:0046961(proton-transporting ATPase activity, rotational mechanism);GO:0048471(perinuclear region of cytoplasm);GO:0051117(ATPase binding);GO:0090383(phagosome acidification)","00190(Oxidative phosphorylation);04142(Lysosome);04145(Phagosome);04721(Synaptic vesicle cycle);04966(Collecting duct acid secretion);05110(Vibrio cholerae infection);05120(Epithelial cell signaling in Helicobacter pylori infection);05152(Tuberculosis);05165(Human papillomavirus infection);05323(Rheumatoid arthritis)","K02154","NA","ATPase H+ transporting V0 subunit a2 [Source:HGNC Symbol;Acc:HGNC:18481]",{"v":0.091163,"d":"0.09"},{"v":0.259188,"d":"0.26"},{"v":0.129615,"d":"0.13"},{"v":0.095105,"d":"0.10"},{"v":0.04424,"d":"0.04"},{"v":0.113339,"d":"0.11"},{"v":1.89947127637682,"d":"1.90"},{"v":0.9255978958713,"d":"0.93"},1,1,"up","no"]
[164785,0,"chr5","+",154959051,154966971,"ENST00000518364",3,481,"ENSG00000082515","MRPL22","GO:0003723(RNA binding);GO:0003735(structural constituent of ribosome);GO:0005739(mitochondrion);GO:0005743(mitochondrial inner membrane);GO:0005762(mitochondrial large ribosomal subunit);GO:0005840(ribosome);GO:0006412(translation);GO:0015934(large ribosomal subunit);GO:0042255(ribosome assembly);GO:0070125(mitochondrial translational elongation);GO:0070126(mitochondrial translational termination)","03010(Ribosome)","K02890","NA","mitochondrial ribosomal protein L22 [Source:HGNC Symbol;Acc:HGNC:14480]",0,0,{"v":0.040194,"d":"0.04"},{"v":0.152478,"d":"0.15"},{"v":0.272718,"d":"0.27"},0,{"v":0.0945305223943781,"d":"0.09"},{"v":-3.40307596205772,"d":"-3.40"},1,1,"down","no"]
[79205,0,"chr16","+",89905009,89909174,"ENST00000563484",4,468,"ENSG00000141002","TCF25","GO:0000122(negative regulation of transcription by RNA polymerase II);GO:0003677(DNA binding);GO:0003700(DNA-binding transcription factor activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0007507(heart development)","NA","NA","NA","transcription factor 25 [Source:HGNC Symbol;Acc:HGNC:29181]",{"v":0.886022,"d":"0.89"},{"v":0.217966,"d":"0.22"},{"v":0.519202,"d":"0.52"},{"v":0.357334,"d":"0.36"},{"v":0.26878,"d":"0.27"},{"v":0.308624,"d":"0.31"},{"v":1.73651868224037,"d":"1.74"},{"v":0.796197931958444,"d":"0.80"},1,1,"up","no"]
[136432,0,"chr3","-",8890109,8902398,"ENST00000429790",3,516,"ENSG00000070950","RAD18","GO:0000403(Y-form DNA binding);GO:0003677(DNA binding);GO:0003684(damaged DNA binding);GO:0003697(single-stranded DNA binding);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005657(replication fork);GO:0005737(cytoplasm);GO:0005813(centrosome);GO:0005815(microtubule organizing center);GO:0005856(cytoskeleton);GO:0006281(DNA repair);GO:0006301(postreplication repair);GO:0006513(protein monoubiquitination);GO:0006974(cellular response to DNA damage stimulus);GO:0009411(response to UV);GO:0016567(protein ubiquitination);GO:0016604(nuclear body);GO:0016740(transferase activity);GO:0031593(polyubiquitin modification-dependent protein binding);GO:0031625(ubiquitin protein ligase binding);GO:0035861(site of double-strand break);GO:0042405(nuclear inclusion body);GO:0042769(DNA damage response, detection of DNA damage);GO:0042802(identical protein binding);GO:0043142(single-stranded DNA-dependent ATPase activity);GO:0044877(protein-containing complex binding);GO:0046872(metal ion binding);GO:0051865(protein autoubiquitination);GO:0051984(positive regulation of chromosome segregation);GO:0060548(negative regulation of cell death);GO:0061630(ubiquitin protein ligase activity);GO:0097505(Rad6-Rad18 complex)","NA","K10627","EC:2.3.2.27","RAD18, E3 ubiquitin protein ligase [Source:HGNC Symbol;Acc:HGNC:18278]",{"v":0.146064,"d":"0.15"},{"v":0.006709,"d":"0.01"},{"v":0.000267,"d":"0.00"},{"v":0.128564,"d":"0.13"},{"v":0.148604,"d":"0.15"},{"v":0.086753,"d":"0.09"},{"v":0.420530829493214,"d":"0.42"},{"v":-1.24971652525929,"d":"-1.25"},1,1,"down","no"]
[207172,0,"chrX","-",153862792,153863969,"ENST00000491983",3,608,"ENSG00000198910","L1CAM","GO:0005515(protein binding);GO:0005886(plasma membrane);GO:0005925(focal adhesion);GO:0006935(chemotaxis);GO:0007155(cell adhesion);GO:0007156(homophilic cell adhesion via plasma membrane adhesion molecules);GO:0007160(cell-matrix adhesion);GO:0007275(multicellular organism development);GO:0007399(nervous system development);GO:0007411(axon guidance);GO:0008046(axon guidance receptor activity);GO:0009986(cell surface);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016477(cell migration);GO:0019904(protein domain specific binding);GO:0030154(cell differentiation);GO:0030424(axon);GO:0030425(dendrite);GO:0030426(growth cone);GO:0031175(neuron projection development);GO:0042995(cell projection);GO:0043025(neuronal cell body);GO:0044295(axonal growth cone);GO:0045773(positive regulation of axon extension);GO:0050808(synapse organization);GO:0050900(leukocyte migration);GO:0061564(axon development);GO:0062023(collagen-containing extracellular matrix)","04360(Axon guidance);04514(Cell adhesion molecules (CAMs))","K06550","NA","L1 cell adhesion molecule [Source:HGNC Symbol;Acc:HGNC:6470]",0,{"v":0.131516,"d":"0.13"},0,0,0,{"v":0.095808,"d":"0.10"},{"v":1.37270374081496,"d":"1.37"},{"v":0.457020294256975,"d":"0.46"},1,1,"up","no"]
[146019,0,"chr3","-",160366083,160399216,"ENST00000486856",5,539,"ENSG00000068885","IFT80","GO:0001649(osteoblast differentiation);GO:0002062(chondrocyte differentiation);GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0005813(centrosome);GO:0005856(cytoskeleton);GO:0005929(cilium);GO:0007224(smoothened signaling pathway);GO:0030992(intraciliary transport particle B);GO:0035735(intraciliary transport involved in cilium assembly);GO:0042995(cell projection);GO:0045880(positive regulation of smoothened signaling pathway);GO:0050680(negative regulation of epithelial cell proliferation);GO:0060271(cilium assembly);GO:0060349(bone morphogenesis);GO:0097542(ciliary tip);GO:1905515(non-motile cilium assembly);GO:2000051(negative regulation of non-canonical Wnt signaling pathway)","NA","K19678","NA","intraflagellar transport 80 [Source:HGNC Symbol;Acc:HGNC:29262]",0,0,0,{"v":0.280166,"d":"0.28"},0,0,"-inf","-inf",1,1,"down","no"]
[2944,0,"chr1","-",25304683,25337411,"ENST00000562018",3,565,"ENSG00000117616","RSRP1","GO:0005515(protein binding)","NA","NA","NA","arginine and serine rich protein 1 [Source:HGNC Symbol;Acc:HGNC:25234]",{"v":0.575196,"d":"0.58"},{"v":0.0058,"d":"0.01"},0,{"v":0.017818,"d":"0.02"},{"v":0.009235,"d":"0.01"},0,{"v":21.476213358962,"d":"21.48"},{"v":4.42466773766002,"d":"4.42"},1,1,"up","no"]
[105279,0,"chr19","+",45522789,45524413,"ENST00000588463",3,655,"ENSG00000125753","VASP","GO:0001843(neural tube closure);GO:0003779(actin binding);GO:0005515(protein binding);GO:0005522(profilin binding);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005856(cytoskeleton);GO:0005886(plasma membrane);GO:0005923(bicellular tight junction);GO:0005925(focal adhesion);GO:0007411(axon guidance);GO:0008154(actin polymerization or depolymerization);GO:0015629(actin cytoskeleton);GO:0016020(membrane);GO:0017124(SH3 domain binding);GO:0030027(lamellipodium);GO:0030036(actin cytoskeleton organization);GO:0030054(cell junction);GO:0030175(filopodium);GO:0030838(positive regulation of actin filament polymerization);GO:0031258(lamellipodium membrane);GO:0031527(filopodium membrane);GO:0034329(cell junction assembly);GO:0042995(cell projection);GO:0045296(cadherin binding);GO:0051289(protein homotetramerization);GO:0070062(extracellular exosome)","04015(Rap1 signaling pathway);04022(cGMP-PKG signaling pathway);04510(Focal adhesion);04530(Tight junction);04611(Platelet activation);04666(Fc gamma R-mediated phagocytosis);04670(Leukocyte transendothelial migration)","K06274","NA","vasodilator stimulated phosphoprotein [Source:HGNC Symbol;Acc:HGNC:12652]",{"v":0.132444,"d":"0.13"},{"v":0.225797,"d":"0.23"},{"v":0.000432,"d":"0.00"},{"v":0.032635,"d":"0.03"},{"v":0.138904,"d":"0.14"},{"v":0.046152,"d":"0.05"},{"v":1.64762438502281,"d":"1.65"},{"v":0.720387383522704,"d":"0.72"},1,1,"up","no"]
[187132,0,"chr8","+",19817391,19819653,"ENST00000518424",3,556,"ENSG00000104613","INTS10","GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0016180(snRNA processing);GO:0032039(integrator complex);GO:0042795(snRNA transcription by RNA polymerase II)","NA","K13147","NA","integrator complex subunit 10 [Source:HGNC Symbol;Acc:HGNC:25548]",{"v":0.320968,"d":"0.32"},{"v":0.220135,"d":"0.22"},{"v":0.292813,"d":"0.29"},{"v":0.052987,"d":"0.05"},{"v":0.047972,"d":"0.05"},{"v":0.120852,"d":"0.12"},{"v":3.75957910112664,"d":"3.76"},{"v":1.91057115586387,"d":"1.91"},1,1,"up","no"]
[2019,0,"chr1","-",16148378,16156052,"ENST00000461614",2,875,"ENSG00000142627","EPHA2","GO:0000166(nucleotide binding);GO:0001501(skeletal system development);GO:0001525(angiogenesis);GO:0001568(blood vessel development);GO:0001570(vasculogenesis);GO:0001618(virus receptor activity);GO:0001649(osteoblast differentiation);GO:0001818(negative regulation of cytokine production);GO:0002043(blood vessel endothelial cell proliferation involved in sprouting angiogenesis);GO:0004672(protein kinase activity);GO:0004713(protein tyrosine kinase activity);GO:0004714(transmembrane receptor protein tyrosine kinase activity);GO:0005003(ephrin receptor activity);GO:0005005(transmembrane-ephrin receptor activity);GO:0005515(protein binding);GO:0005524(ATP binding);GO:0005886(plasma membrane);GO:0005887(integral component of plasma membrane);GO:0005925(focal adhesion);GO:0006468(protein phosphorylation);GO:0006915(apoptotic process);GO:0006954(inflammatory response);GO:0007155(cell adhesion);GO:0007169(transmembrane receptor protein tyrosine kinase signaling pathway);GO:0007275(multicellular organism development);GO:0007411(axon guidance);GO:0008630(intrinsic apoptotic signaling pathway in response to DNA damage);GO:0009986(cell surface);GO:0010591(regulation of lamellipodium assembly);GO:0014028(notochord formation);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016032(viral process);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0016477(cell migration);GO:0016525(negative regulation of angiogenesis);GO:0016740(transferase activity);GO:0018108(peptidyl-tyrosine phosphorylation);GO:0021915(neural tube development);GO:0030027(lamellipodium);GO:0030054(cell junction);GO:0030154(cell differentiation);GO:0030182(neuron differentiation);GO:0030216(keratinocyte differentiation);GO:0030316(osteoclast differentiation);GO:0031256(leading edge membrane);GO:0031258(lamellipodium membrane);GO:0032587(ruffle membrane);GO:0032682(negative regulation of chemokine production);GO:0033598(mammary gland epithelial cell proliferation);GO:0033628(regulation of cell adhesion mediated by integrin);GO:0036342(post-anal tail morphogenesis);GO:0042995(cell projection);GO:0043005(neuron projection);GO:0043235(receptor complex);GO:0043491(protein kinase B signaling);GO:0043535(regulation of blood vessel endothelial cell migration);GO:0045296(cadherin binding);GO:0045765(regulation of angiogenesis);GO:0046058(cAMP metabolic process);GO:0046718(viral entry into host cell);GO:0046849(bone remodeling);GO:0048013(ephrin receptor signaling pathway);GO:0048320(axial mesoderm formation);GO:0048514(blood vessel morphogenesis);GO:0048570(notochord morphogenesis);GO:0048870(cell motility);GO:0050830(defense response to Gram-positive bacterium);GO:0051898(negative regulation of protein kinase B signaling);GO:0060035(notochord cell development);GO:0060326(cell chemotaxis);GO:0060444(branching involved in mammary gland duct morphogenesis);GO:0070160(tight junction);GO:0070309(lens fiber cell morphogenesis);GO:0070372(regulation of ERK1 and ERK2 cascade);GO:0070848(response to growth factor);GO:0072659(protein localization to plasma membrane);GO:0090630(activation of GTPase activity);GO:1901491(negative regulation of lymphangiogenesis);GO:1903078(positive regulation of protein localization to plasma membrane);GO:1903348(positive regulation of bicellular tight junction assembly);GO:1904238(pericyte cell differentiation)","04010(MAPK signaling pathway);04014(Ras signaling pathway);04015(Rap1 signaling pathway);04151(PI3K-Akt signaling pathway);04360(Axon guidance)","K05103","EC:2.7.10.1","EPH receptor A2 [Source:HGNC Symbol;Acc:HGNC:3386]",0,{"v":0.856222,"d":"0.86"},{"v":0.635348,"d":"0.64"},{"v":0.20235,"d":"0.20"},{"v":0.251206,"d":"0.25"},{"v":0.235323,"d":"0.24"},{"v":2.16521333935277,"d":"2.17"},{"v":1.11450918128584,"d":"1.11"},1,1,"up","no"]
[4635,0,"chr1","-",39522280,39541841,"ENST00000648902",3,497,"ENSG00000243970","PPIEL","NA","NA","NA","NA","peptidylprolyl isomerase E like pseudogene [Source:HGNC Symbol;Acc:HGNC:33195]",{"v":0.510764,"d":"0.51"},0,{"v":0.174948,"d":"0.17"},{"v":0.109326,"d":"0.11"},0,{"v":0.067487,"d":"0.07"},{"v":3.87817637843371,"d":"3.88"},{"v":1.95537841832484,"d":"1.96"},1,1,"up","no"]
[9993,0,"chr1","-",118150397,118185223,"ENST00000465053",3,527,"ENSG00000155761","SPAG17","GO:0003351(epithelial cilium movement);GO:0005737(cytoplasm);GO:0005856(cytoskeleton);GO:0005874(microtubule);GO:0005929(cilium);GO:0030030(cell projection organization);GO:0031514(motile cilium);GO:0042995(cell projection);GO:1904158(axonemal central apparatus assembly);GO:1990716(axonemal central apparatus)","NA","NA","NA","sperm associated antigen 17 [Source:HGNC Symbol;Acc:HGNC:26620]",0,0,0,0,0,0,1,0,1,1,"no","no"]
[104910,0,"chr19","+",44128454,44130700,"ENST00000592360",1,2247,"ENSG00000256294","ZNF225","GO:0000981(DNA-binding transcription factor activity, RNA polymerase II-specific);GO:0003676(nucleic acid binding);GO:0003677(DNA binding);GO:0005622(intracellular);GO:0005634(nucleus);GO:0006355(regulation of transcription, DNA-templated);GO:0006357(regulation of transcription by RNA polymerase II);GO:0046872(metal ion binding)","05168(Herpes simplex virus 1 infection)","K09228","NA","zinc finger protein 225 [Source:HGNC Symbol;Acc:HGNC:13018]",{"v":0.0111,"d":"0.01"},{"v":0.12536,"d":"0.13"},{"v":0.058703,"d":"0.06"},{"v":0.06742,"d":"0.07"},{"v":0.023087,"d":"0.02"},{"v":0.078935,"d":"0.08"},{"v":1.15179825545024,"d":"1.15"},{"v":0.203888041997165,"d":"0.20"},1,1,"up","no"]
[170457,0,"chr6","+",41072983,41097950,"ENST00000353205",9,1660,"ENSG00000001167","NFYA","GO:0000978(RNA polymerase II proximal promoter sequence-specific DNA binding);GO:0000980(RNA polymerase II distal enhancer sequence-specific DNA binding);GO:0000981(DNA-binding transcription factor activity, RNA polymerase II-specific);GO:0003677(DNA binding);GO:0003700(DNA-binding transcription factor activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0006355(regulation of transcription, DNA-templated);GO:0006357(regulation of transcription by RNA polymerase II);GO:0006366(transcription by RNA polymerase II);GO:0016602(CCAAT-binding factor complex);GO:0032993(protein-DNA complex);GO:0044212(transcription regulatory region DNA binding);GO:0045540(regulation of cholesterol biosynthetic process);GO:0045893(positive regulation of transcription, DNA-templated);GO:0048511(rhythmic process);GO:0090575(RNA polymerase II transcription factor complex)","04612(Antigen processing and presentation);05152(Tuberculosis)","K08064","NA","nuclear transcription factor Y subunit alpha [Source:HGNC Symbol;Acc:HGNC:7804]",0,0,0,{"v":0.372855,"d":"0.37"},{"v":0.235261,"d":"0.24"},0,"-inf","-inf",1,1,"down","no"]
[80142,0,"chr17","-",4704816,4705217,"ENST00000466297",1,402,"ENSG00000213939","AC091153","NA","NA","NA","NA","ribosomal protein S12 (RPS12) pseudogene",0,{"v":0.238356,"d":"0.24"},{"v":0.102392,"d":"0.10"},0,{"v":0.039354,"d":"0.04"},0,{"v":8.65853534583524,"d":"8.66"},{"v":3.11412300324197,"d":"3.11"},1,1,"up","no"]
[161953,0,"chr5","+",119456313,119475873,"ENST00000507695",5,324,"ENSG00000133835","HSD17B4","GO:0000038(very long-chain fatty acid metabolic process);GO:0001649(osteoblast differentiation);GO:0003857(3-hydroxyacyl-CoA dehydrogenase activity);GO:0005102(signaling receptor binding);GO:0005777(peroxisome);GO:0005778(peroxisomal membrane);GO:0005782(peroxisomal matrix);GO:0005829(cytosol);GO:0006625(protein targeting to peroxisome);GO:0006629(lipid metabolic process);GO:0006631(fatty acid metabolic process);GO:0006635(fatty acid beta-oxidation);GO:0006699(bile acid biosynthetic process);GO:0008209(androgen metabolic process);GO:0008210(estrogen metabolic process);GO:0016020(membrane);GO:0016491(oxidoreductase activity);GO:0016508(long-chain-enoyl-CoA hydratase activity);GO:0016829(lyase activity);GO:0016853(isomerase activity);GO:0033540(fatty acid beta-oxidation using acyl-CoA oxidase);GO:0033989(3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA hydratase activity);GO:0036109(alpha-linolenic acid metabolic process);GO:0036111(very long-chain fatty-acyl-CoA metabolic process);GO:0036112(medium-chain fatty-acyl-CoA metabolic process);GO:0042803(protein homodimerization activity);GO:0044594(17-beta-hydroxysteroid dehydrogenase (NAD+) activity);GO:0055114(oxidation-reduction process);GO:0060009(Sertoli cell development)","00120(Primary bile acid biosynthesis);01040(Biosynthesis of unsaturated fatty acids);04146(Peroxisome)","K12405","4.2.1.107;4.2.1.119;EC:1.1.1.-","hydroxysteroid 17-beta dehydrogenase 4 [Source:HGNC Symbol;Acc:HGNC:5213]",{"v":0.168747,"d":"0.17"},{"v":0.479,"d":"0.48"},{"v":0.019,"d":"0.02"},{"v":0.073304,"d":"0.07"},{"v":0.352568,"d":"0.35"},{"v":0.117345,"d":"0.12"},{"v":1.22740451789984,"d":"1.23"},{"v":0.295610798951191,"d":"0.30"},1,1,"up","no"]
[199373,0,"chr9","-",127908325,127912394,"ENST00000474282",2,384,"ENSG00000136840","ST6GALNAC4","GO:0000139(Golgi membrane);GO:0005794(Golgi apparatus);GO:0006486(protein glycosylation);GO:0006664(glycolipid metabolic process);GO:0008373(sialyltransferase activity);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016266(O-glycan processing);GO:0016740(transferase activity);GO:0016757(transferase activity, transferring glycosyl groups);GO:0047290((alpha-N-acetylneuraminyl-2,3-beta-galactosyl-1,3)-N-acetyl-galactosaminide 6-alpha-sialyltransferase activity);GO:0097503(sialylation)","00604(Glycosphingolipid biosynthesis - ganglio series)","K03374","EC:2.4.99.7","ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 4 [Source:HGNC Symbol;Acc:HGNC:17846]",{"v":0.176672,"d":"0.18"},{"v":0.126711,"d":"0.13"},0,{"v":0.847178,"d":"0.85"},0,0,{"v":0.358110102009259,"d":"0.36"},{"v":-1.48152487834259,"d":"-1.48"},1,1,"down","no"]
[204277,0,"chrX","-",72473417,72475729,"ENST00000648158",1,2313,"ENSG00000147099","HDAC8","GO:0000118(histone deacetylase complex);GO:0000122(negative regulation of transcription by RNA polymerase II);GO:0000228(nuclear chromosome);GO:0004407(histone deacetylase activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0005886(plasma membrane);GO:0006325(chromatin organization);GO:0006333(chromatin assembly or disassembly);GO:0007062(sister chromatid cohesion);GO:0008134(transcription factor binding);GO:0016575(histone deacetylation);GO:0016787(hydrolase activity);GO:0030544(Hsp70 protein binding);GO:0031397(negative regulation of protein ubiquitination);GO:0031647(regulation of protein stability);GO:0032041(NAD-dependent histone deacetylase activity (H3-K14 specific));GO:0032204(regulation of telomere maintenance);GO:0045944(positive regulation of transcription by RNA polymerase II);GO:0046872(metal ion binding);GO:0051879(Hsp90 protein binding);GO:0070932(histone H3 deacetylation);GO:0070933(histone H4 deacetylation);GO:0071922(regulation of cohesin loading)","05034(Alcoholism);05203(Viral carcinogenesis)","K11405","EC:3.5.1.98","histone deacetylase 8 [Source:HGNC Symbol;Acc:HGNC:13315]",{"v":0.170295,"d":"0.17"},{"v":0.807948,"d":"0.81"},{"v":0.08565,"d":"0.09"},{"v":0.116667,"d":"0.12"},{"v":0.047298,"d":"0.05"},{"v":0.062945,"d":"0.06"},{"v":4.68861222511128,"d":"4.69"},{"v":2.22916096491014,"d":"2.23"},1,1,"up","no"]
[153741,0,"chr4","-",102901088,103019666,"ENST00000504216",9,1184,"ENSG00000164037","SLC9B1","GO:0005886(plasma membrane);GO:0005929(cilium);GO:0006811(ion transport);GO:0006812(cation transport);GO:0006814(sodium ion transport);GO:0007338(single fertilization);GO:0015297(antiporter activity);GO:0015299(solute:proton antiporter activity);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0030317(flagellated sperm motility);GO:0031514(motile cilium);GO:0034220(ion transmembrane transport);GO:0042995(cell projection);GO:0051453(regulation of intracellular pH);GO:0055085(transmembrane transport);GO:0097228(sperm principal piece);GO:1902600(proton transmembrane transport)","NA","NA","NA","solute carrier family 9 member B1 [Source:HGNC Symbol;Acc:HGNC:24244]",{"v":0.130888,"d":"0.13"},0,0,0,0,{"v":0.111639,"d":"0.11"},{"v":1.17242182391458,"d":"1.17"},{"v":0.229491728275113,"d":"0.23"},1,1,"up","no"]
[110464,0,"chr2","+",24972183,24972830,"ENST00000421842",2,255,"ENSG00000224165","DNAJC27-AS1","NA","NA","NA","NA","DNAJC27 antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:42943]",0,{"v":0.159582,"d":"0.16"},{"v":0.177326,"d":"0.18"},{"v":0.106081,"d":"0.11"},{"v":0.855592,"d":"0.86"},{"v":0.111199,"d":"0.11"},{"v":0.314024412977503,"d":"0.31"},{"v":-1.67105137299186,"d":"-1.67"},1,1,"down","no"]
[185806,0,"chr7","-",156654185,156657693,"ENST00000455709",2,742,"ENSG00000224903","AC005534","NA","NA","NA","NA","novel transcript",0,{"v":0.052912,"d":"0.05"},0,0,0,0,"inf","inf",1,1,"up","no"]
[156824,0,"chr4","-",185514315,185525122,"ENST00000512380",3,764,"ENSG00000154553","PDLIM3","GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0007015(actin filament organization);GO:0007507(heart development);GO:0008092(cytoskeletal protein binding);GO:0008307(structural constituent of muscle);GO:0015629(actin cytoskeleton);GO:0030018(Z disc);GO:0046872(metal ion binding)","NA","NA","NA","PDZ and LIM domain 3 [Source:HGNC Symbol;Acc:HGNC:20767]",{"v":0.025031,"d":"0.03"},0,0,0,0,0,"inf","inf",1,1,"up","no"]
[31346,0,"chr11","-",62634571,62639471,"ENST00000524437",3,671,"ENSG00000089597","GANAB","GO:0003723(RNA binding);GO:0003824(catalytic activity);GO:0004553(hydrolase activity, hydrolyzing O-glycosyl compounds);GO:0005515(protein binding);GO:0005783(endoplasmic reticulum);GO:0005788(endoplasmic reticulum lumen);GO:0005794(Golgi apparatus);GO:0005975(carbohydrate metabolic process);GO:0006457(protein folding);GO:0006491(N-glycan processing);GO:0008152(metabolic process);GO:0016020(membrane);GO:0016787(hydrolase activity);GO:0016798(hydrolase activity, acting on glycosyl bonds);GO:0017177(glucosidase II complex);GO:0030246(carbohydrate binding);GO:0033919(glucan 1,3-alpha-glucosidase activity);GO:0042470(melanosome);GO:0043231(intracellular membrane-bounded organelle);GO:0070062(extracellular exosome);GO:0090599(alpha-glucosidase activity)","00510(N-Glycan biosynthesis);04141(Protein processing in endoplasmic reticulum)","K05546","EC:3.2.1.207","glucosidase II alpha subunit [Source:HGNC Symbol;Acc:HGNC:4138]",{"v":0.788661,"d":"0.79"},{"v":0.603398,"d":"0.60"},{"v":0.890347,"d":"0.89"},{"v":0.39374,"d":"0.39"},{"v":0.746323,"d":"0.75"},{"v":1.118998,"d":"1.12"},{"v":1.01033393963244,"d":"1.01"},{"v":0.0148322171593692,"d":"0.01"},1,1,"up","no"]
[41563,0,"chr12","-",32728169,32729024,"ENST00000620472",1,856,"ENSG00000274105","AC084824","NA","NA","NA","NA","novel transcript, sense intronic to YARS2",{"v":0.185955,"d":"0.19"},{"v":0.220412,"d":"0.22"},{"v":0.340975,"d":"0.34"},{"v":0.461085,"d":"0.46"},{"v":0.275939,"d":"0.28"},{"v":0.292438,"d":"0.29"},{"v":0.725953944876061,"d":"0.73"},{"v":-0.462050069540282,"d":"-0.46"},1,1,"down","no"]
[104776,0,"chr19","+",43612107,43614487,"ENST00000417606",1,2381,"ENSG00000226763","SRRM5","NA","NA","NA","NA","serine/arginine repetitive matrix 5 [Source:HGNC Symbol;Acc:HGNC:37248]",{"v":0.113819,"d":"0.11"},{"v":0.064933,"d":"0.06"},{"v":0.110311,"d":"0.11"},{"v":0.061903,"d":"0.06"},{"v":0.239009,"d":"0.24"},{"v":0.094286,"d":"0.09"},{"v":0.731438418210619,"d":"0.73"},{"v":-0.451191689829195,"d":"-0.45"},1,1,"down","no"]
[58777,0,"chr14","+",77098258,77106090,"ENST00000556863",2,538,"ENSG00000198894","CIPC","GO:0005515(protein binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0042754(negative regulation of circadian rhythm);GO:0045892(negative regulation of transcription, DNA-templated);GO:0048511(rhythmic process)","NA","NA","NA","CLOCK interacting pacemaker [Source:HGNC Symbol;Acc:HGNC:20365]",{"v":0.000831,"d":"0.00"},{"v":0.569806,"d":"0.57"},{"v":0.08826,"d":"0.09"},{"v":0.070869,"d":"0.07"},{"v":0.004293,"d":"0.00"},{"v":0.088492,"d":"0.09"},{"v":4.02615884732423,"d":"4.03"},{"v":2.00940409320463,"d":"2.01"},1,1,"up","no"]
[79352,0,"chr17","-",212502,353097,"ENST00000323434",9,2809,"ENSG00000181031","RPH3AL","GO:0005515(protein binding);GO:0005623(cell);GO:0005737(cytoplasm);GO:0006886(intracellular protein transport);GO:0006887(exocytosis);GO:0008092(cytoskeletal protein binding);GO:0016020(membrane);GO:0017137(Rab GTPase binding);GO:0017157(regulation of exocytosis);GO:0017158(regulation of calcium ion-dependent exocytosis);GO:0030141(secretory granule);GO:0030274(LIM domain binding);GO:0030658(transport vesicle membrane);GO:0030667(secretory granule membrane);GO:0031410(cytoplasmic vesicle);GO:0032024(positive regulation of insulin secretion);GO:0042493(response to drug);GO:0042593(glucose homeostasis);GO:0045744(negative regulation of G protein-coupled receptor signaling pathway);GO:0046872(metal ion binding);GO:0050714(positive regulation of protein secretion)","NA","K19939","NA","rabphilin 3A like (without C2 domains) [Source:HGNC Symbol;Acc:HGNC:10296]",{"v":0.197942,"d":"0.20"},0,{"v":0.145,"d":"0.15"},0,0,0,"inf","inf",1,1,"up","no"]
[89539,0,"chr17","+",68944531,69012050,"ENST00000630625",2,445,"ENSG00000231749","ABCA9-AS1","NA","NA","NA","NA","ABCA9 antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:39983]",{"v":0.039166,"d":"0.04"},0,0,0,0,0,"inf","inf",1,1,"up","no"]
[120766,0,"chr2","+",200738608,200791630,"ENST00000487742",26,3284,"ENSG00000243478","AOX2P","NA","NA","NA","NA","aldehyde oxidase 2 pseudogene [Source:HGNC Symbol;Acc:HGNC:18450]",0,0,0,0,0,0,1,0,1,1,"no","no"]
[59107,0,"chr14","-",87976358,87989647,"ENST00000554916",7,631,"ENSG00000054983","GALC","GO:0003824(catalytic activity);GO:0004336(galactosylceramidase activity);GO:0005764(lysosome);GO:0006629(lipid metabolic process);GO:0006665(sphingolipid metabolic process);GO:0006683(galactosylceramide catabolic process);GO:0006687(glycosphingolipid metabolic process);GO:0008152(metabolic process);GO:0016042(lipid catabolic process);GO:0016787(hydrolase activity);GO:0016798(hydrolase activity, acting on glycosyl bonds);GO:0042552(myelination);GO:0043202(lysosomal lumen)","00600(Sphingolipid metabolism);04142(Lysosome)","NA","NA","galactosylceramidase [Source:HGNC Symbol;Acc:HGNC:4115]",0,0,0,0,0,{"v":0.01844,"d":"0.02"},"-inf","-inf",1,1,"down","no"]
[181782,0,"chr7","-",99756967,99784184,"ENST00000651514",13,2781,"ENSG00000160868","CYP3A4","GO:0002933(lipid hydroxylation);GO:0004497(monooxygenase activity);GO:0005496(steroid binding);GO:0005506(iron ion binding);GO:0005737(cytoplasm);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0006629(lipid metabolic process);GO:0006706(steroid catabolic process);GO:0006805(xenobiotic metabolic process);GO:0008202(steroid metabolic process);GO:0008209(androgen metabolic process);GO:0008395(steroid hydroxylase activity);GO:0009822(alkaloid catabolic process);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016098(monoterpenoid metabolic process);GO:0016491(oxidoreductase activity);GO:0016705(oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen);GO:0016712(oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen);GO:0017144(drug metabolic process);GO:0019825(oxygen binding);GO:0019899(enzyme binding);GO:0020037(heme binding);GO:0030343(vitamin D3 25-hydroxylase activity);GO:0031090(organelle membrane);GO:0034875(caffeine oxidase activity);GO:0036378(calcitriol biosynthetic process from calciol);GO:0042359(vitamin D metabolic process);GO:0042737(drug catabolic process);GO:0042738(exogenous drug catabolic process);GO:0042759(long-chain fatty acid biosynthetic process);GO:0043231(intracellular membrane-bounded organelle);GO:0046483(heterocycle metabolic process);GO:0046872(metal ion binding);GO:0050649(testosterone 6-beta-hydroxylase activity);GO:0055114(oxidation-reduction process);GO:0070576(vitamin D 24-hydroxylase activity);GO:0070989(oxidative demethylation);GO:0101020(estrogen 16-alpha-hydroxylase activity)","00140(Steroid hormone biosynthesis);00591(Linoleic acid metabolism);00830(Retinol metabolism);00980(Metabolism of xenobiotics by cytochrome P450);00982(Drug metabolism - cytochrome P450);00983(Drug metabolism - other enzymes);04976(Bile secretion);05204(Chemical carcinogenesis)","NA","NA","cytochrome P450 family 3 subfamily A member 4 [Source:HGNC Symbol;Acc:HGNC:2637]",0,0,0,0,0,0,1,0,1,1,"no","no"]
[11332,0,"chr1","-",151773479,151790479,"ENST00000368825",13,2651,"ENSG00000182134","TDRKH","GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0005737(cytoplasm);GO:0005739(mitochondrion);GO:0007140(male meiotic nuclear division);GO:0007283(spermatogenesis);GO:0009566(fertilization);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0030154(cell differentiation);GO:0031047(gene silencing by RNA);GO:0034587(piRNA metabolic process);GO:0043046(DNA methylation involved in gamete generation);GO:0071546(pi-body);GO:0071547(piP-body)","NA","K18406","NA","tudor and KH domain containing [Source:HGNC Symbol;Acc:HGNC:11713]",{"v":0.100496,"d":"0.10"},0,{"v":0.025456,"d":"0.03"},{"v":0.014802,"d":"0.01"},0,0,{"v":8.5091203891366,"d":"8.51"},{"v":3.08901000431796,"d":"3.09"},1,1,"up","no"]
[190968,0,"chr8","+",93229659,93229916,"ENST00000598428",1,258,"ENSG00000268080","AC016885","NA","NA","NA","NA","variable charge X-linked protein pseudogene",0,0,0,0,0,0,1,0,1,1,"no","no"]
[155884,0,"chr4","+",157076204,157138872,"ENST00000506411",8,858,"ENSG00000109738","GLRB","GO:0001964(startle response);GO:0004888(transmembrane signaling receptor activity);GO:0005216(ion channel activity);GO:0005230(extracellular ligand-gated ion channel activity);GO:0005254(chloride channel activity);GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0005886(plasma membrane);GO:0005887(integral component of plasma membrane);GO:0006811(ion transport);GO:0006821(chloride transport);GO:0007165(signal transduction);GO:0007218(neuropeptide signaling pathway);GO:0007268(chemical synaptic transmission);GO:0007340(acrosome reaction);GO:0007399(nervous system development);GO:0007601(visual perception);GO:0007628(adult walking behavior);GO:0008144(drug binding);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016594(glycine binding);GO:0016933(extracellularly glycine-gated ion channel activity);GO:0016934(extracellularly glycine-gated chloride channel activity);GO:0016935(glycine-gated chloride channel complex);GO:0030054(cell junction);GO:0030425(dendrite);GO:0034220(ion transmembrane transport);GO:0034707(chloride channel complex);GO:0042391(regulation of membrane potential);GO:0042995(cell projection);GO:0043005(neuron projection);GO:0043200(response to amino acid);GO:0045202(synapse);GO:0045211(postsynaptic membrane);GO:0050877(nervous system process);GO:0050905(neuromuscular process);GO:0051291(protein heterooligomerization);GO:0060012(synaptic transmission, glycinergic);GO:0060013(righting reflex);GO:0060078(regulation of postsynaptic membrane potential);GO:0060079(excitatory postsynaptic potential);GO:0097112(gamma-aminobutyric acid receptor clustering);GO:0098690(glycinergic synapse);GO:0098982(GABA-ergic synapse);GO:1902476(chloride transmembrane transport);GO:1904315(transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential)","04080(Neuroactive ligand-receptor interaction)","NA","NA","glycine receptor beta [Source:HGNC Symbol;Acc:HGNC:4329]",0,{"v":0.052826,"d":"0.05"},0,0,0,{"v":0.674236,"d":"0.67"},{"v":0.0783494206776262,"d":"0.08"},{"v":-3.67393358244899,"d":"-3.67"},1,1,"down","no"]
[139387,0,"chr3","+",47825912,47829135,"ENST00000471082",3,464,"ENSG00000132153","DHX30","GO:0000166(nucleotide binding);GO:0002151(G-quadruplex RNA binding);GO:0003676(nucleic acid binding);GO:0003682(chromatin binding);GO:0003723(RNA binding);GO:0003725(double-stranded RNA binding);GO:0004003(ATP-dependent DNA helicase activity);GO:0004004(ATP-dependent RNA helicase activity);GO:0004386(helicase activity);GO:0005515(protein binding);GO:0005524(ATP binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005739(mitochondrion);GO:0005829(cytosol);GO:0007417(central nervous system development);GO:0016787(hydrolase activity);GO:0032508(DNA duplex unwinding);GO:0034459(ATP-dependent 3'-5' RNA helicase activity);GO:0035770(ribonucleoprotein granule);GO:0042254(ribosome biogenesis);GO:0042645(mitochondrial nucleoid);GO:1902775(mitochondrial large ribosomal subunit assembly)","NA","K13185","EC:3.6.4.13","DExH-box helicase 30 [Source:HGNC Symbol;Acc:HGNC:16716]",{"v":0.071834,"d":"0.07"},0,{"v":0.006384,"d":"0.01"},{"v":0.064259,"d":"0.06"},{"v":0.018604,"d":"0.02"},{"v":0.090033,"d":"0.09"},{"v":0.4523991301129,"d":"0.45"},{"v":-1.1443319396158,"d":"-1.14"},1,1,"down","no"]
[79186,0,"chr16","+",89873592,89884063,"ENST00000561585",2,981,"ENSG00000141002","TCF25","GO:0000122(negative regulation of transcription by RNA polymerase II);GO:0003677(DNA binding);GO:0003700(DNA-binding transcription factor activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0007507(heart development)","NA","NA","NA","transcription factor 25 [Source:HGNC Symbol;Acc:HGNC:29181]",{"v":0.014862,"d":"0.01"},{"v":0.28428,"d":"0.28"},{"v":2.468796,"d":"2.47"},{"v":0.370509,"d":"0.37"},{"v":0.438902,"d":"0.44"},{"v":0.294143,"d":"0.29"},{"v":2.50820349525261,"d":"2.51"},{"v":1.32665440144221,"d":"1.33"},1,1,"up","no"]
[133677,0,"chr22","-",31082156,31083565,"ENST00000609017",1,1410,"ENSG00000273387","AC005005","NA","NA","NA","NA","novel transcript, antisense to SMTN",{"v":0.089342,"d":"0.09"},{"v":0.202653,"d":"0.20"},{"v":0.199077,"d":"0.20"},{"v":0.052825,"d":"0.05"},{"v":0.095894,"d":"0.10"},{"v":0.031448,"d":"0.03"},{"v":2.72564898122298,"d":"2.73"},{"v":1.44659977870354,"d":"1.45"},1,1,"up","no"]
[79110,0,"chr16","+",89686728,89691512,"ENST00000514965",5,474,"ENSG00000185324","CDK10","GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0004693(cyclin-dependent protein serine/threonine kinase activity);GO:0005515(protein binding);GO:0005524(ATP binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005856(cytoskeleton);GO:0006468(protein phosphorylation);GO:0007089(traversing start control point of mitotic cell cycle);GO:0008285(negative regulation of cell population proliferation);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0016740(transferase activity);GO:0018107(peptidyl-threonine phosphorylation);GO:0030030(cell projection organization);GO:0032956(regulation of actin cytoskeleton organization);GO:0036064(ciliary basal body);GO:0042995(cell projection);GO:0043410(positive regulation of MAPK cascade);GO:0097472(cyclin-dependent protein kinase activity);GO:1902018(negative regulation of cilium assembly)","NA","K02449","EC:2.7.11.22","cyclin dependent kinase 10 [Source:HGNC Symbol;Acc:HGNC:1770]",0,{"v":0.076542,"d":"0.08"},0,0,0,0,"inf","inf",1,1,"up","no"]
[87577,0,"chr17","-",50163523,50165316,"ENST00000572855",1,1794,"ENSG00000261959","AC015909","NA","NA","NA","NA","novel transcript, antisense to SGCA",0,0,0,{"v":0.046461,"d":"0.05"},0,0,"-inf","-inf",1,1,"down","no"]
[48080,0,"chr12","+",111686068,111749132,"ENST00000413681",18,2951,"ENSG00000111271","ACAD10","GO:0003995(acyl-CoA dehydrogenase activity);GO:0005739(mitochondrion);GO:0005759(mitochondrial matrix);GO:0006635(fatty acid beta-oxidation);GO:0016491(oxidoreductase activity);GO:0016627(oxidoreductase activity, acting on the CH-CH group of donors);GO:0016787(hydrolase activity);GO:0050660(flavin adenine dinucleotide binding);GO:0055114(oxidation-reduction process)","NA","K11729","NA","acyl-CoA dehydrogenase family member 10 [Source:HGNC Symbol;Acc:HGNC:21597]",{"v":0.007048,"d":"0.01"},{"v":0.006281,"d":"0.01"},{"v":0.001715,"d":"0.00"},{"v":0.037092,"d":"0.04"},{"v":0.00958,"d":"0.01"},0,{"v":0.322334590332533,"d":"0.32"},{"v":-1.63336907985787,"d":"-1.63"},1,1,"down","no"]
[24984,0,"chr10","-",122849094,122879641,"ENST00000462859",3,645,"ENSG00000213185","FAM24B","GO:0005576(extracellular region)","NA","NA","NA","family with sequence similarity 24 member B [Source:HGNC Symbol;Acc:HGNC:23475]",0,{"v":0.025419,"d":"0.03"},{"v":0.464686,"d":"0.46"},{"v":0.232736,"d":"0.23"},{"v":0.310099,"d":"0.31"},0,{"v":0.902861827258744,"d":"0.90"},{"v":-0.14742287836757,"d":"-0.15"},1,1,"down","no"]
[126661,0,"chr20","+",37095785,37097178,"ENST00000598590",1,1394,"ENSG00000269846","AL136172","NA","NA","NA","NA","novel transcript, antisense to RBL1",0,{"v":0.063139,"d":"0.06"},0,0,0,0,"inf","inf",1,1,"up","no"]
[26081,0,"chr11","+",1389934,1462689,"ENST00000528841",20,4528,"ENSG00000174672","BRSK2","GO:0000086(G2/M transition of mitotic cell cycle);GO:0000166(nucleotide binding);GO:0000287(magnesium ion binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005524(ATP binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005783(endoplasmic reticulum);GO:0005813(centrosome);GO:0005815(microtubule organizing center);GO:0005856(cytoskeleton);GO:0006468(protein phosphorylation);GO:0006887(exocytosis);GO:0006915(apoptotic process);GO:0007049(cell cycle);GO:0007399(nervous system development);GO:0007409(axonogenesis);GO:0010975(regulation of neuron projection development);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0016740(transferase activity);GO:0018105(peptidyl-serine phosphorylation);GO:0019901(protein kinase binding);GO:0030010(establishment of cell polarity);GO:0030182(neuron differentiation);GO:0031532(actin cytoskeleton reorganization);GO:0035556(intracellular signal transduction);GO:0036503(ERAD pathway);GO:0043462(regulation of ATPase activity);GO:0046872(metal ion binding);GO:0048156(tau protein binding);GO:0048471(perinuclear region of cytoplasm);GO:0048812(neuron projection morphogenesis);GO:0050321(tau-protein kinase activity);GO:0050770(regulation of axonogenesis);GO:0051117(ATPase binding);GO:0051301(cell division);GO:0060590(ATPase regulator activity);GO:0061178(regulation of insulin secretion involved in cellular response to glucose stimulus);GO:0070059(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress);GO:0090176(microtubule cytoskeleton organization involved in establishment of planar polarity);GO:0150034(distal axon);GO:1904152(regulation of retrograde protein transport, ER to cytosol);GO:2000807(regulation of synaptic vesicle clustering)","NA","NA","NA","BR serine/threonine kinase 2 [Source:HGNC Symbol;Acc:HGNC:11405]",0,{"v":0.005376,"d":"0.01"},0,{"v":0.037049,"d":"0.04"},{"v":0.035061,"d":"0.04"},{"v":0.131321,"d":"0.13"},{"v":0.0264266508054328,"d":"0.03"},{"v":-5.24186259387449,"d":"-5.24"},1,1,"down","no"]
[27728,0,"chr11","-",12980211,12989539,"ENST00000534477",3,888,"ENSG00000251381","LINC00958","NA","NA","NA","NA","long intergenic non-protein coding RNA 958 [Source:HGNC Symbol;Acc:HGNC:48671]",0,0,{"v":0.245293,"d":"0.25"},{"v":0.205112,"d":"0.21"},{"v":0.555897,"d":"0.56"},0,{"v":0.322326017169311,"d":"0.32"},{"v":-1.63340745186299,"d":"-1.63"},1,1,"down","no"]
[140116,0,"chr3","-",49831916,49840552,"ENST00000475495",3,511,"ENSG00000183763","TRAIP","GO:0004842(ubiquitin-protein transferase activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005730(nucleolus);GO:0005737(cytoplasm);GO:0006915(apoptotic process);GO:0007165(signal transduction);GO:0008283(cell population proliferation);GO:0010804(negative regulation of tumor necrosis factor-mediated signaling pathway);GO:0016567(protein ubiquitination);GO:0016740(transferase activity);GO:0032088(negative regulation of NF-kappaB transcription factor activity);GO:0032688(negative regulation of interferon-beta production);GO:0046872(metal ion binding);GO:0048471(perinuclear region of cytoplasm);GO:0061630(ubiquitin protein ligase activity)","NA","K11985","EC:2.3.2.27","TRAF interacting protein [Source:HGNC Symbol;Acc:HGNC:30764]",{"v":0.059738,"d":"0.06"},{"v":0.161036,"d":"0.16"},{"v":0.314764,"d":"0.31"},{"v":0.040681,"d":"0.04"},{"v":0.280162,"d":"0.28"},{"v":0.050403,"d":"0.05"},{"v":1.4425421418682,"d":"1.44"},{"v":0.528613465821321,"d":"0.53"},1,1,"up","no"]
[198455,0,"chr9","-",113315671,113340256,"ENST00000461942",11,2371,"ENSG00000148225","WDR31","GO:0005515(protein binding)","NA","NA","NA","WD repeat domain 31 [Source:HGNC Symbol;Acc:HGNC:21421]",0,{"v":0.0279,"d":"0.03"},0,0,0,0,"inf","inf",1,1,"up","no"]
[164226,0,"chr5","-",149001348,149063044,"ENST00000323829",18,7324,"ENSG00000169247","SH3TC2","GO:0005515(protein binding);GO:0005886(plasma membrane);GO:0022011(myelination in peripheral nervous system);GO:0031410(cytoplasmic vesicle);GO:0032287(peripheral nervous system myelin maintenance);GO:0033157(regulation of intracellular protein transport);GO:1901184(regulation of ERBB signaling pathway)","NA","NA","NA","SH3 domain and tetratricopeptide repeats 2 [Source:HGNC Symbol;Acc:HGNC:29427]",0,{"v":0.02894,"d":"0.03"},0,0,{"v":0.007083,"d":"0.01"},0,{"v":4.0858393336157,"d":"4.09"},{"v":2.03063247446929,"d":"2.03"},1,1,"up","no"]
[104266,0,"chr19","-",41391890,41397331,"ENST00000593771",4,404,"ENSG00000077348","EXOSC5","GO:0000175(3'-5'-exoribonuclease activity);GO:0000176(nuclear exosome (RNase complex));GO:0000177(cytoplasmic exosome (RNase complex));GO:0000178(exosome (RNase complex));GO:0003723(RNA binding);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005730(nucleolus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0006364(rRNA processing);GO:0006401(RNA catabolic process);GO:0016075(rRNA catabolic process);GO:0034427(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5');GO:0034475(U4 snRNA 3'-end processing);GO:0035327(transcriptionally active chromatin);GO:0043488(regulation of mRNA stability);GO:0043928(exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay);GO:0045006(DNA deamination);GO:0051607(defense response to virus);GO:0071028(nuclear mRNA surveillance);GO:0071051(polyadenylation-dependent snoRNA 3'-end processing);GO:0090503(RNA phosphodiester bond hydrolysis, exonucleolytic)","03018(RNA degradation)","K12590","NA","exosome component 5 [Source:HGNC Symbol;Acc:HGNC:24662]",0,0,0,{"v":0.048549,"d":"0.05"},0,{"v":0.038669,"d":"0.04"},"-inf","-inf",1,1,"down","no"]
[14116,0,"chr1","+",173824684,173857873,"ENST00000648271",15,3361,"ENSG00000117593","DARS2","GO:0000049(tRNA binding);GO:0000166(nucleotide binding);GO:0003676(nucleic acid binding);GO:0004812(aminoacyl-tRNA ligase activity);GO:0004815(aspartate-tRNA ligase activity);GO:0005515(protein binding);GO:0005524(ATP binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005739(mitochondrion);GO:0005759(mitochondrial matrix);GO:0006412(translation);GO:0006418(tRNA aminoacylation for protein translation);GO:0016874(ligase activity);GO:0042803(protein homodimerization activity);GO:0043039(tRNA aminoacylation);GO:0050560(aspartate-tRNA(Asn) ligase activity);GO:0070145(mitochondrial asparaginyl-tRNA aminoacylation)","00970(Aminoacyl-tRNA biosynthesis)","K01876","EC:6.1.1.12","aspartyl-tRNA synthetase 2, mitochondrial [Source:HGNC Symbol;Acc:HGNC:25538]",0,0,0,{"v":0.075811,"d":"0.08"},{"v":0.196916,"d":"0.20"},0,"-inf","-inf",1,1,"down","no"]
[172712,0,"chr6","+",100889603,100890338,"ENST00000604292",1,736,"ENSG00000270987","AL133338","NA","NA","NA","NA","mitogen-activated protein kinase 1 interacting protein 1-like (MAPK1IP1L) pseudogene",{"v":0.362951,"d":"0.36"},{"v":0.025656,"d":"0.03"},{"v":0.098718,"d":"0.10"},{"v":0.056928,"d":"0.06"},{"v":0.056988,"d":"0.06"},{"v":0.098489,"d":"0.10"},{"v":2.29431981356371,"d":"2.29"},{"v":1.19806650786779,"d":"1.20"},1,1,"up","no"]
[100657,0,"chr19","-",17301289,17303425,"ENST00000594194",3,570,"ENSG00000127220","ABHD8","GO:0003824(catalytic activity);GO:0016787(hydrolase activity);GO:0052689(carboxylic ester hydrolase activity);GO:0055088(lipid homeostasis);GO:0070062(extracellular exosome)","NA","K13701","NA","abhydrolase domain containing 8 [Source:HGNC Symbol;Acc:HGNC:23759]",0,{"v":0.023396,"d":"0.02"},0,0,0,0,"inf","inf",1,1,"up","no"]
[87301,0,"chr17","+",48851101,48852858,"ENST00000514006",3,500,"ENSG00000136436","CALCOCO2","GO:0000421(autophagosome membrane);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005776(autophagosome);GO:0005829(cytosol);GO:0005856(cytoskeleton);GO:0006914(autophagy);GO:0016020(membrane);GO:0016032(viral process);GO:0031410(cytoplasmic vesicle);GO:0034341(response to interferon-gamma);GO:0042803(protein homodimerization activity);GO:0043231(intracellular membrane-bounded organelle);GO:0048471(perinuclear region of cytoplasm);GO:0098792(xenophagy);GO:1901098(positive regulation of autophagosome maturation)","04137(Mitophagy - animal)","K21348","NA","calcium binding and coiled-coil domain 2 [Source:HGNC Symbol;Acc:HGNC:29912]",{"v":0.164043,"d":"0.16"},{"v":0.037649,"d":"0.04"},{"v":0.348929,"d":"0.35"},{"v":0.387982,"d":"0.39"},{"v":0.16748,"d":"0.17"},{"v":0.47405,"d":"0.47"},{"v":0.534836893596189,"d":"0.53"},{"v":-0.902829107443342,"d":"-0.90"},1,1,"down","no"]
[20503,0,"chr10","-",42279734,42281819,"ENST00000452851",1,2086,"ENSG00000228755","PABPC1P8","NA","NA","NA","NA","poly(A) binding protein cytoplasmic 1 pseudogene 8 [Source:HGNC Symbol;Acc:HGNC:37988]",{"v":0.02013,"d":"0.02"},0,0,0,0,0,"inf","inf",1,1,"up","no"]
[193088,0,"chr8","-",139904432,139908695,"ENST00000518723",2,558,"ENSG00000167632","TRAPPC9","GO:0000139(Golgi membrane);GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0005783(endoplasmic reticulum);GO:0005794(Golgi apparatus);GO:0005802(trans-Golgi network);GO:0005829(cytosol);GO:0021987(cerebral cortex development);GO:0030008(TRAPP complex);GO:0030154(cell differentiation);GO:0030182(neuron differentiation);GO:0048208(COPII vesicle coating);GO:0051092(positive regulation of NF-kappaB transcription factor activity)","NA","K20306","NA","trafficking protein particle complex 9 [Source:HGNC Symbol;Acc:HGNC:30832]",0,0,0,0,0,0,1,0,1,1,"no","no"]
[24565,0,"chr10","+",116274270,116281071,"ENST00000648277",2,2848,"ENSG00000285587","AC012470","NA","NA","NA","NA","novel transcript",{"v":0.029488,"d":"0.03"},0,0,{"v":0.029528,"d":"0.03"},{"v":0.027323,"d":"0.03"},0,{"v":0.518689205115126,"d":"0.52"},{"v":-0.947057750034543,"d":"-0.95"},1,1,"down","no"]
[136930,0,"chr3","-",11564915,11610504,"ENST00000437722",3,544,"ENSG00000144560","VGLL4","GO:0005515(protein binding);GO:0005634(nucleus);GO:0006355(regulation of transcription, DNA-templated)","NA","NA","NA","vestigial like family member 4 [Source:HGNC Symbol;Acc:HGNC:28966]",{"v":0.115783,"d":"0.12"},0,0,0,0,{"v":0.261552,"d":"0.26"},{"v":0.442676790848474,"d":"0.44"},{"v":-1.17567435869025,"d":"-1.18"},1,1,"down","no"]
[145951,0,"chr3","+",158822443,158829718,"ENST00000465235",5,2042,"ENSG00000118855","MFSD1","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0055085(transmembrane transport)","NA","NA","NA","major facilitator superfamily domain containing 1 [Source:HGNC Symbol;Acc:HGNC:25874]",{"v":0.060229,"d":"0.06"},0,{"v":0.284544,"d":"0.28"},{"v":0.420467,"d":"0.42"},{"v":0.201485,"d":"0.20"},{"v":0.214872,"d":"0.21"},{"v":0.412001806831544,"d":"0.41"},{"v":-1.27927743053423,"d":"-1.28"},1,1,"down","no"]
[82396,0,"chr17","-",18302604,18314944,"ENST00000461127",6,823,"ENSG00000177302","TOP3A","GO:0003676(nucleic acid binding);GO:0003677(DNA binding);GO:0003697(single-stranded DNA binding);GO:0003916(DNA topoisomerase activity);GO:0003917(DNA topoisomerase type I activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005694(chromosome);GO:0005739(mitochondrion);GO:0005759(mitochondrial matrix);GO:0006260(DNA replication);GO:0006265(DNA topological change);GO:0008270(zinc ion binding);GO:0016605(PML body);GO:0016853(isomerase activity);GO:0032042(mitochondrial DNA metabolic process);GO:0046872(metal ion binding);GO:0051304(chromosome separation);GO:0051321(meiotic cell cycle);GO:1901796(regulation of signal transduction by p53 class mediator)","03440(Homologous recombination);03460(Fanconi anemia pathway)","K03165","EC:5.6.2.1","DNA topoisomerase III alpha [Source:HGNC Symbol;Acc:HGNC:11992]",{"v":0.857707,"d":"0.86"},{"v":0.768245,"d":"0.77"},{"v":0.020506,"d":"0.02"},{"v":0.327855,"d":"0.33"},{"v":0.005156,"d":"0.01"},0,{"v":4.94415499788295,"d":"4.94"},{"v":2.3057239720392,"d":"2.31"},1,1,"up","no"]
[77001,0,"chr16","+",69930166,69933981,"ENST00000568818",4,563,"ENSG00000198373","WWP2","GO:0000122(negative regulation of transcription by RNA polymerase II);GO:0000151(ubiquitin ligase complex);GO:0000209(protein polyubiquitination);GO:0001085(RNA polymerase II transcription factor binding);GO:0004842(ubiquitin-protein transferase activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0006464(cellular protein modification process);GO:0006511(ubiquitin-dependent protein catabolic process);GO:0006858(extracellular transport);GO:0008134(transcription factor binding);GO:0010629(negative regulation of gene expression);GO:0016020(membrane);GO:0016032(viral process);GO:0016567(protein ubiquitination);GO:0016740(transferase activity);GO:0016874(ligase activity);GO:0032410(negative regulation of transporter activity);GO:0034765(regulation of ion transmembrane transport);GO:0042391(regulation of membrane potential);GO:0043161(proteasome-mediated ubiquitin-dependent protein catabolic process);GO:0043433(negative regulation of DNA-binding transcription factor activity);GO:0045732(positive regulation of protein catabolic process);GO:0045746(negative regulation of Notch signaling pathway);GO:0045892(negative regulation of transcription, DNA-templated);GO:0045944(positive regulation of transcription by RNA polymerase II);GO:0046718(viral entry into host cell);GO:0051224(negative regulation of protein transport);GO:0051865(protein autoubiquitination);GO:0061630(ubiquitin protein ligase activity);GO:0070062(extracellular exosome);GO:0070534(protein K63-linked ubiquitination);GO:1901016(regulation of potassium ion transmembrane transporter activity)","04120(Ubiquitin mediated proteolysis)","K05630","EC:2.3.2.26","WW domain containing E3 ubiquitin protein ligase 2 [Source:HGNC Symbol;Acc:HGNC:16804]",{"v":0.162491,"d":"0.16"},{"v":0.251701,"d":"0.25"},{"v":0.078096,"d":"0.08"},{"v":0.104089,"d":"0.10"},{"v":0.314828,"d":"0.31"},{"v":0.177174,"d":"0.18"},{"v":0.825860481033936,"d":"0.83"},{"v":-0.276030018232548,"d":"-0.28"},1,1,"down","no"]
[48857,0,"chr12","+",120650085,120667032,"ENST00000288616",7,1369,"ENSG00000157782","CABP1","GO:0000139(Golgi membrane);GO:0004857(enzyme inhibitor activity);GO:0005509(calcium ion binding);GO:0005515(protein binding);GO:0005615(extracellular space);GO:0005737(cytoplasm);GO:0005794(Golgi apparatus);GO:0005856(cytoskeleton);GO:0005886(plasma membrane);GO:0005938(cell cortex);GO:0007601(visual perception);GO:0008139(nuclear localization sequence binding);GO:0014069(postsynaptic density);GO:0016020(membrane);GO:0030054(cell junction);GO:0042308(negative regulation of protein import into nucleus);GO:0043086(negative regulation of catalytic activity);GO:0045202(synapse);GO:0045211(postsynaptic membrane);GO:0046872(metal ion binding);GO:0048306(calcium-dependent protein binding);GO:0048471(perinuclear region of cytoplasm);GO:0050896(response to stimulus)","NA","NA","NA","calcium binding protein 1 [Source:HGNC Symbol;Acc:HGNC:1384]",0,{"v":0.090281,"d":"0.09"},0,0,0,0,"inf","inf",1,1,"up","no"]
[54902,0,"chr14","-",23562187,23563853,"ENST00000554982",4,716,"ENSG00000213983","AP1G2","GO:0000139(Golgi membrane);GO:0005515(protein binding);GO:0005623(cell);GO:0005768(endosome);GO:0005794(Golgi apparatus);GO:0005798(Golgi-associated vesicle);GO:0006886(intracellular protein transport);GO:0010008(endosome membrane);GO:0015031(protein transport);GO:0016020(membrane);GO:0016032(viral process);GO:0016192(vesicle-mediated transport);GO:0030117(membrane coat);GO:0030121(AP-1 adaptor complex);GO:0030133(transport vesicle);GO:0030659(cytoplasmic vesicle membrane);GO:0031410(cytoplasmic vesicle)","04142(Lysosome);05170(Human immunodeficiency virus 1 infection)","K12391","NA","adaptor related protein complex 1 subunit gamma 2 [Source:HGNC Symbol;Acc:HGNC:556]",{"v":0.057694,"d":"0.06"},{"v":0.083036,"d":"0.08"},{"v":0.366235,"d":"0.37"},{"v":0.297438,"d":"0.30"},{"v":0.336628,"d":"0.34"},{"v":0.08738,"d":"0.09"},{"v":0.702706786093484,"d":"0.70"},{"v":-0.509005264041356,"d":"-0.51"},1,1,"down","no"]
[98088,0,"chr19","+",7637105,7642118,"ENST00000595950",6,552,"ENSG00000076944","STXBP2","GO:0001909(leukocyte mediated cytotoxicity);GO:0002576(platelet degranulation);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0006887(exocytosis);GO:0006904(vesicle docking involved in exocytosis);GO:0015031(protein transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016192(vesicle-mediated transport);GO:0016324(apical plasma membrane);GO:0017075(syntaxin-1 binding);GO:0030348(syntaxin-3 binding);GO:0042581(specific granule);GO:0042582(azurophil granule);GO:0042589(zymogen granule membrane);GO:0043304(regulation of mast cell degranulation);GO:0043312(neutrophil degranulation);GO:0044194(cytolytic granule);GO:0045335(phagocytic vesicle);GO:0070062(extracellular exosome);GO:0070820(tertiary granule);GO:0071346(cellular response to interferon-gamma)","NA","K15300","NA","syntaxin binding protein 2 [Source:HGNC Symbol;Acc:HGNC:11445]",0,0,0,{"v":0.051341,"d":"0.05"},0,0,"-inf","-inf",1,1,"down","no"]
[37839,0,"chr11","+",125580780,125582397,"ENST00000530540",2,595,"ENSG00000149547","EI24","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005794(Golgi apparatus);GO:0005829(cytosol);GO:0006914(autophagy);GO:0006915(apoptotic process);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016236(macroautophagy);GO:0030308(negative regulation of cell growth);GO:0031965(nuclear membrane)","04115(p53 signaling pathway)","K10134","NA","EI24, autophagy associated transmembrane protein [Source:HGNC Symbol;Acc:HGNC:13276]",{"v":0.164476,"d":"0.16"},{"v":0.221517,"d":"0.22"},{"v":0.356379,"d":"0.36"},{"v":0.232623,"d":"0.23"},{"v":0.430855,"d":"0.43"},{"v":0.15116,"d":"0.15"},{"v":0.911290659163948,"d":"0.91"},{"v":-0.134016815115188,"d":"-0.13"},1,1,"down","no"]
[77081,0,"chr16","+",70299178,70319709,"ENST00000562912",5,569,"ENSG00000157349","DDX19B","GO:0000166(nucleotide binding);GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0004386(helicase activity);GO:0005515(protein binding);GO:0005524(ATP binding);GO:0005634(nucleus);GO:0005643(nuclear pore);GO:0005737(cytoplasm);GO:0006406(mRNA export from nucleus);GO:0010043(response to zinc ion);GO:0015031(protein transport);GO:0016020(membrane);GO:0016787(hydrolase activity);GO:0031965(nuclear membrane);GO:0043065(positive regulation of apoptotic process);GO:0051028(mRNA transport);GO:0070062(extracellular exosome)","NA","K18655","EC:3.6.4.13","DEAD-box helicase 19B [Source:HGNC Symbol;Acc:HGNC:2742]",{"v":0.041066,"d":"0.04"},{"v":0.312577,"d":"0.31"},{"v":0.058748,"d":"0.06"},0,{"v":0.08721,"d":"0.09"},0,{"v":4.7287123036349,"d":"4.73"},{"v":2.24144737043918,"d":"2.24"},1,1,"up","no"]
[76846,0,"chr16","+",68843604,68867976,"ENST00000564180",4,1764,"ENSG00000103047","TANGO6","GO:0016020(membrane);GO:0016021(integral component of membrane)","NA","NA","NA","transport and golgi organization 6 homolog [Source:HGNC Symbol;Acc:HGNC:25749]",{"v":0.436428,"d":"0.44"},{"v":0.397615,"d":"0.40"},{"v":0.342948,"d":"0.34"},{"v":0.048222,"d":"0.05"},{"v":0.431671,"d":"0.43"},{"v":0.023609,"d":"0.02"},{"v":2.33760938387534,"d":"2.34"},{"v":1.22503387468254,"d":"1.23"},1,1,"up","no"]
[163632,0,"chr5","+",140855897,141012347,"ENST00000307360",4,5409,"ENSG00000250120","PCDHA10","GO:0005509(calcium ion binding);GO:0005576(extracellular region);GO:0005886(plasma membrane);GO:0005887(integral component of plasma membrane);GO:0007155(cell adhesion);GO:0007156(homophilic cell adhesion via plasma membrane adhesion molecules);GO:0007399(nervous system development);GO:0016020(membrane);GO:0016021(integral component of membrane)","NA","K16493","NA","protocadherin alpha 10 [Source:HGNC Symbol;Acc:HGNC:8664]",{"v":0.315552,"d":"0.32"},0,0,0,0,0,"inf","inf",1,1,"up","no"]
[128028,0,"chr20","+",57391637,57409333,"ENST00000344785",5,2193,"ENSG00000132819","RBM38","GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0003729(mRNA binding);GO:0003730(mRNA 3'-UTR binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0006397(mRNA processing);GO:0007049(cell cycle);GO:0008380(RNA splicing);GO:0010830(regulation of myotube differentiation);GO:0030154(cell differentiation);GO:0043484(regulation of RNA splicing);GO:0070935(3'-UTR-mediated mRNA stabilization);GO:1990904(ribonucleoprotein complex)","NA","NA","NA","RNA binding motif protein 38 [Source:HGNC Symbol;Acc:HGNC:15818]",0,0,{"v":0.002915,"d":"0.00"},{"v":0.007501,"d":"0.01"},0,{"v":0.002725,"d":"0.00"},{"v":0.285057696068844,"d":"0.29"},{"v":-1.81067414259908,"d":"-1.81"},1,1,"down","no"]
[12421,0,"chr1","-",156293373,156295653,"ENST00000476177",5,795,"ENSG00000198715","GLMP","GO:0003700(DNA-binding transcription factor activity);GO:0005634(nucleus);GO:0005764(lysosome);GO:0005765(lysosomal membrane);GO:0005829(cytosol);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0044212(transcription regulatory region DNA binding);GO:0045944(positive regulation of transcription by RNA polymerase II)","NA","NA","NA","glycosylated lysosomal membrane protein [Source:HGNC Symbol;Acc:HGNC:29436]",0,{"v":0.023769,"d":"0.02"},0,{"v":0.068328,"d":"0.07"},0,{"v":0.044237,"d":"0.04"},{"v":0.211157997601386,"d":"0.21"},{"v":-2.24360520469178,"d":"-2.24"},1,1,"down","no"]
[146644,0,"chr3","-",177025985,177026415,"ENST00000638074",2,100,"ENSG00000177565","TBL1XR1","GO:0000118(histone deacetylase complex);GO:0000122(negative regulation of transcription by RNA polymerase II);GO:0001835(blastocyst hatching);GO:0002021(response to dietary excess);GO:0003677(DNA binding);GO:0003714(transcription corepressor activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0006325(chromatin organization);GO:0006357(regulation of transcription by RNA polymerase II);GO:0008013(beta-catenin binding);GO:0010468(regulation of gene expression);GO:0016042(lipid catabolic process);GO:0016575(histone deacetylation);GO:0017053(transcriptional repressor complex);GO:0019216(regulation of lipid metabolic process);GO:0035264(multicellular organism growth);GO:0042393(histone binding);GO:0043161(proteasome-mediated ubiquitin-dependent protein catabolic process);GO:0044212(transcription regulatory region DNA binding);GO:0045892(negative regulation of transcription, DNA-templated);GO:0045893(positive regulation of transcription, DNA-templated);GO:0045944(positive regulation of transcription by RNA polymerase II);GO:0047485(protein N-terminus binding);GO:0050872(white fat cell differentiation);GO:0060612(adipose tissue development);GO:0060613(fat pad development);GO:0072686(mitotic spindle);GO:0090207(regulation of triglyceride metabolic process);GO:0090263(positive regulation of canonical Wnt signaling pathway)","04310(Wnt signaling pathway)","K04508","NA","transducin beta like 1 X-linked receptor 1 [Source:HGNC Symbol;Acc:HGNC:29529]",0,{"v":0.023409,"d":"0.02"},0,0,{"v":0.209714,"d":"0.21"},{"v":0.194422,"d":"0.19"},{"v":0.057923570283271,"d":"0.06"},{"v":-4.10970566001895,"d":"-4.11"},1,1,"down","no"]
[91935,0,"chr17","+",82032184,82033772,"ENST00000584341",5,730,"ENSG00000169750","RAC3","GO:0000166(nucleotide binding);GO:0000902(cell morphogenesis);GO:0003924(GTPase activity);GO:0005515(protein binding);GO:0005525(GTP binding);GO:0005622(intracellular);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005856(cytoskeleton);GO:0005886(plasma membrane);GO:0007015(actin filament organization);GO:0007264(small GTPase mediated signal transduction);GO:0007266(Rho protein signal transduction);GO:0012505(endomembrane system);GO:0014041(regulation of neuron maturation);GO:0016020(membrane);GO:0016477(cell migration);GO:0019901(protein kinase binding);GO:0021894(cerebral cortex GABAergic interneuron development);GO:0022604(regulation of cell morphogenesis);GO:0030027(lamellipodium);GO:0030031(cell projection assembly);GO:0030036(actin cytoskeleton organization);GO:0030426(growth cone);GO:0030838(positive regulation of actin filament polymerization);GO:0031175(neuron projection development);GO:0031532(actin cytoskeleton reorganization);GO:0031941(filamentous actin);GO:0033630(positive regulation of cell adhesion mediated by integrin);GO:0035556(intracellular signal transduction);GO:0042995(cell projection);GO:0043005(neuron projection);GO:0043025(neuronal cell body);GO:0043652(engulfment of apoptotic cell);GO:0048306(calcium-dependent protein binding);GO:0048471(perinuclear region of cytoplasm);GO:0048873(homeostasis of number of cells within a tissue);GO:0050885(neuromuscular process controlling balance);GO:0050905(neuromuscular process);GO:0051056(regulation of small GTPase mediated signal transduction);GO:0051932(synaptic transmission, GABAergic);GO:0070062(extracellular exosome);GO:0071944(cell periphery);GO:1900026(positive regulation of substrate adhesion-dependent cell spreading)","04010(MAPK signaling pathway);04014(Ras signaling pathway);04015(Rap1 signaling pathway);04024(cAMP signaling pathway);04062(Chemokine signaling pathway);04071(Sphingolipid signaling pathway);04310(Wnt signaling pathway);04360(Axon guidance);04370(VEGF signaling pathway);04510(Focal adhesion);04520(Adherens junction);04650(Natural killer cell mediated cytotoxicity);04662(B cell receptor signaling pathway);04664(Fc epsilon RI signaling pathway);04810(Regulation of actin cytoskeleton);05163(Human cytomegalovirus infection);05170(Human immunodeficiency virus 1 infection);05200(Pathways in cancer);05210(Colorectal cancer);05212(Pancreatic cancer);05231(Choline metabolism in cancer);05416(Viral myocarditis);05418(Fluid shear stress and atherosclerosis)","K07861","NA","Rac family small GTPase 3 [Source:NCBI gene;Acc:5881]",0,0,0,0,0,{"v":0.017852,"d":"0.02"},"-inf","-inf",1,1,"down","no"]
[87534,0,"chr17","+",50070873,50074514,"ENST00000512553",4,351,"ENSG00000005884","ITGA3","GO:0001764(neuron migration);GO:0001968(fibronectin binding);GO:0002020(protease binding);GO:0005178(integrin binding);GO:0005515(protein binding);GO:0005518(collagen binding);GO:0005886(plasma membrane);GO:0005925(focal adhesion);GO:0007155(cell adhesion);GO:0007160(cell-matrix adhesion);GO:0007229(integrin-mediated signaling pathway);GO:0007507(heart development);GO:0007613(memory);GO:0008305(integrin complex);GO:0009897(external side of plasma membrane);GO:0009986(cell surface);GO:0010628(positive regulation of gene expression);GO:0010634(positive regulation of epithelial cell migration);GO:0010811(positive regulation of cell-substrate adhesion);GO:0010976(positive regulation of neuron projection development);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016323(basolateral plasma membrane);GO:0017015(regulation of transforming growth factor beta receptor signaling pathway);GO:0019904(protein domain specific binding);GO:0030054(cell junction);GO:0030111(regulation of Wnt signaling pathway);GO:0030198(extracellular matrix organization);GO:0030324(lung development);GO:0030426(growth cone);GO:0030510(regulation of BMP signaling pathway);GO:0031345(negative regulation of cell projection organization);GO:0031527(filopodium membrane);GO:0034667(integrin alpha3-beta1 complex);GO:0034698(response to gonadotropin);GO:0035024(negative regulation of Rho protein signal transduction);GO:0035640(exploration behavior);GO:0042493(response to drug);GO:0042995(cell projection);GO:0043235(receptor complex);GO:0043236(laminin binding);GO:0043588(skin development);GO:0045202(synapse);GO:0046872(metal ion binding);GO:0046982(protein heterodimerization activity);GO:0048333(mesodermal cell differentiation);GO:0048471(perinuclear region of cytoplasm);GO:0050900(leukocyte migration);GO:0060076(excitatory synapse);GO:0060135(maternal process involved in female pregnancy);GO:0070062(extracellular exosome);GO:0071438(invadopodium membrane);GO:0071944(cell periphery);GO:0072006(nephron development);GO:0097060(synaptic membrane);GO:0097062(dendritic spine maintenance);GO:0097205(renal filtration);GO:1903078(positive regulation of protein localization to plasma membrane);GO:1990812(growth cone filopodium)","04151(PI3K-Akt signaling pathway);04510(Focal adhesion);04512(ECM-receptor interaction);04640(Hematopoietic cell lineage);04810(Regulation of actin cytoskeleton);05165(Human papillomavirus infection);05200(Pathways in cancer);05222(Small cell lung cancer);05410(Hypertrophic cardiomyopathy (HCM));05412(Arrhythmogenic right ventricular cardiomyopathy (ARVC));05414(Dilated cardiomyopathy (DCM))","K06482","NA","integrin subunit alpha 3 [Source:HGNC Symbol;Acc:HGNC:6139]",0,0,0,0,0,{"v":0.216246,"d":"0.22"},"-inf","-inf",1,1,"down","no"]
[150469,0,"chr4","+",26420570,26424994,"ENST00000506903",3,658,"ENSG00000168214","RBPJ","GO:0000122(negative regulation of transcription by RNA polymerase II);GO:0000978(RNA polymerase II proximal promoter sequence-specific DNA binding);GO:0000981(DNA-binding transcription factor activity, RNA polymerase II-specific);GO:0001103(RNA polymerase II repressing transcription factor binding);GO:0001228(DNA-binding transcription activator activity, RNA polymerase II-specific);GO:0001525(angiogenesis);GO:0001756(somitogenesis);GO:0001837(epithelial to mesenchymal transition);GO:0001974(blood vessel remodeling);GO:0002193(MAML1-RBP-Jkappa- ICN1 complex);GO:0002437(inflammatory response to antigenic stimulus);GO:0003139(secondary heart field specification);GO:0003151(outflow tract morphogenesis);GO:0003157(endocardium development);GO:0003160(endocardium morphogenesis);GO:0003176(aortic valve development);GO:0003177(pulmonary valve development);GO:0003198(epithelial to mesenchymal transition involved in endocardial cushion formation);GO:0003214(cardiac left ventricle morphogenesis);GO:0003222(ventricular trabecula myocardium morphogenesis);GO:0003256(regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation);GO:0003677(DNA binding);GO:0003682(chromatin binding);GO:0003700(DNA-binding transcription factor activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005667(transcription factor complex);GO:0005730(nucleolus);GO:0005737(cytoplasm);GO:0006355(regulation of transcription, DNA-templated);GO:0006357(regulation of transcription by RNA polymerase II);GO:0006367(transcription initiation from RNA polymerase II promoter);GO:0006959(humoral immune response);GO:0007219(Notch signaling pathway);GO:0007221(positive regulation of transcription of Notch receptor target);GO:0007507(heart development);GO:0008134(transcription factor binding);GO:0008284(positive regulation of cell population proliferation);GO:0008285(negative regulation of cell population proliferation);GO:0009912(auditory receptor cell fate commitment);GO:0009957(epidermal cell fate specification);GO:0010468(regulation of gene expression);GO:0010628(positive regulation of gene expression);GO:0017053(transcriptional repressor complex);GO:0021983(pituitary gland development);GO:0030097(hemopoiesis);GO:0030182(neuron differentiation);GO:0030183(B cell differentiation);GO:0030216(keratinocyte differentiation);GO:0030279(negative regulation of ossification);GO:0030513(positive regulation of BMP signaling pathway);GO:0035019(somatic stem cell population maintenance);GO:0035912(dorsal aorta morphogenesis);GO:0036302(atrioventricular canal development);GO:0042127(regulation of cell population proliferation);GO:0042742(defense response to bacterium);GO:0043011(myeloid dendritic cell differentiation);GO:0043565(sequence-specific DNA binding);GO:0045165(cell fate commitment);GO:0045596(negative regulation of cell differentiation);GO:0045747(positive regulation of Notch signaling pathway);GO:0045892(negative regulation of transcription, DNA-templated);GO:0045944(positive regulation of transcription by RNA polymerase II);GO:0047485(protein N-terminus binding);GO:0048505(regulation of timing of cell differentiation);GO:0048733(sebaceous gland development);GO:0048820(hair follicle maturation);GO:0048844(artery morphogenesis);GO:0060045(positive regulation of cardiac muscle cell proliferation);GO:0060412(ventricular septum morphogenesis);GO:0060486(Clara cell differentiation);GO:0060716(labyrinthine layer blood vessel development);GO:0060844(arterial endothelial cell fate commitment);GO:0061314(Notch signaling involved in heart development);GO:0061419(positive regulation of transcription from RNA polymerase II promoter in response to hypoxia);GO:0070491(repressing transcription factor binding);GO:0072554(blood vessel lumenization);GO:0072602(interleukin-4 secretion);GO:0097101(blood vessel endothelial cell fate specification);GO:0120163(negative regulation of cold-induced thermogenesis);GO:1901186(positive regulation of ERBB signaling pathway);GO:1901189(positive regulation of ephrin receptor signaling pathway);GO:1901297(positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment);GO:2000138(positive regulation of cell proliferation involved in heart morphogenesis)","04330(Notch signaling pathway);04658(Th1 and Th2 cell differentiation);05165(Human papillomavirus infection);05169(Epstein-Barr virus infection);05203(Viral carcinogenesis)","K06053","NA","recombination signal binding protein for immunoglobulin kappa J region [Source:HGNC Symbol;Acc:HGNC:5724]",{"v":0.184338,"d":"0.18"},{"v":0.008692,"d":"0.01"},{"v":0.229675,"d":"0.23"},{"v":0.052357,"d":"0.05"},{"v":0.131755,"d":"0.13"},{"v":0.467826,"d":"0.47"},{"v":0.648382208124085,"d":"0.65"},{"v":-0.625083591637276,"d":"-0.63"},1,1,"down","no"]
[182810,0,"chr7","+",107570068,107577191,"ENST00000471763",3,2148,"ENSG00000105865","DUS4L","GO:0002943(tRNA dihydrouridine synthesis);GO:0003824(catalytic activity);GO:0008033(tRNA processing);GO:0016491(oxidoreductase activity);GO:0017150(tRNA dihydrouridine synthase activity);GO:0050660(flavin adenine dinucleotide binding);GO:0055114(oxidation-reduction process)","NA","K05545","EC:1.3.1.90","dihydrouridine synthase 4 like [Source:HGNC Symbol;Acc:HGNC:21517]",{"v":0.113694,"d":"0.11"},{"v":0.101206,"d":"0.10"},{"v":0.291329,"d":"0.29"},{"v":0.162722,"d":"0.16"},{"v":0.103522,"d":"0.10"},{"v":0.145479,"d":"0.15"},{"v":1.22953782033066,"d":"1.23"},{"v":0.298116112619478,"d":"0.30"},1,1,"up","no"]
[24404,0,"chr10","+",112447258,112737784,"ENST00000432306",8,1738,"ENSG00000151532","VTI1A","GO:0000139(Golgi membrane);GO:0000149(SNARE binding);GO:0005484(SNAP receptor activity);GO:0005515(protein binding);GO:0005768(endosome);GO:0005776(autophagosome);GO:0005789(endoplasmic reticulum membrane);GO:0005794(Golgi apparatus);GO:0005829(cytosol);GO:0006623(protein targeting to vacuole);GO:0006886(intracellular protein transport);GO:0006888(endoplasmic reticulum to Golgi vesicle-mediated transport);GO:0006891(intra-Golgi vesicle-mediated transport);GO:0006896(Golgi to vacuole transport);GO:0006914(autophagy);GO:0008021(synaptic vesicle);GO:0012507(ER to Golgi transport vesicle membrane);GO:0015031(protein transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016192(vesicle-mediated transport);GO:0030136(clathrin-coated vesicle);GO:0031201(SNARE complex);GO:0031410(cytoplasmic vesicle);GO:0031902(late endosome membrane);GO:0032588(trans-Golgi network membrane);GO:0042147(retrograde transport, endosome to Golgi);GO:0043025(neuronal cell body);GO:0043231(intracellular membrane-bounded organelle);GO:0044306(neuron projection terminus);GO:0048280(vesicle fusion with Golgi apparatus);GO:0048471(perinuclear region of cytoplasm);GO:0050882(voluntary musculoskeletal movement);GO:0090161(Golgi ribbon formation)","04130(SNARE interactions in vesicular transport)","K08493","NA","vesicle transport through interaction with t-SNAREs 1A [Source:HGNC Symbol;Acc:HGNC:17792]",0,0,{"v":0.012649,"d":"0.01"},{"v":0.006091,"d":"0.01"},{"v":0.014924,"d":"0.01"},0,{"v":0.601903402331668,"d":"0.60"},{"v":-0.732396123117133,"d":"-0.73"},1,1,"down","no"]
[181414,0,"chr7","-",95594771,95596460,"ENST00000473301",2,691,"ENSG00000004799","PDK4","GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0004740(pyruvate dehydrogenase (acetyl-transferring) kinase activity);GO:0005524(ATP binding);GO:0005739(mitochondrion);GO:0005759(mitochondrial matrix);GO:0005975(carbohydrate metabolic process);GO:0006006(glucose metabolic process);GO:0006468(protein phosphorylation);GO:0006885(regulation of pH);GO:0008286(insulin receptor signaling pathway);GO:0009267(cellular response to starvation);GO:0010510(regulation of acetyl-CoA biosynthetic process from pyruvate);GO:0010565(regulation of cellular ketone metabolic process);GO:0010906(regulation of glucose metabolic process);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0016740(transferase activity);GO:0042304(regulation of fatty acid biosynthetic process);GO:0042593(glucose homeostasis);GO:0042594(response to starvation);GO:0045124(regulation of bone resorption);GO:0046320(regulation of fatty acid oxidation);GO:0071398(cellular response to fatty acid);GO:0072593(reactive oxygen species metabolic process);GO:2000811(negative regulation of anoikis)","NA","NA","NA","pyruvate dehydrogenase kinase 4 [Source:HGNC Symbol;Acc:HGNC:8812]",{"v":0.021615,"d":"0.02"},{"v":0.009778,"d":"0.01"},{"v":0.089422,"d":"0.09"},{"v":0.05995,"d":"0.06"},{"v":0.03968,"d":"0.04"},{"v":0.001481,"d":"0.00"},{"v":1.19487493942301,"d":"1.19"},{"v":0.256859627648801,"d":"0.26"},1,1,"up","no"]
[118632,0,"chr2","-",162267248,162268137,"ENST00000649426",2,791,"ENSG00000115267","IFIH1","GO:0000166(nucleotide binding);GO:0002376(immune system process);GO:0003677(DNA binding);GO:0003723(RNA binding);GO:0003725(double-stranded RNA binding);GO:0003727(single-stranded RNA binding);GO:0004386(helicase activity);GO:0005515(protein binding);GO:0005524(ATP binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0008270(zinc ion binding);GO:0009597(detection of virus);GO:0009615(response to virus);GO:0016032(viral process);GO:0016579(protein deubiquitination);GO:0016787(hydrolase activity);GO:0016925(protein sumoylation);GO:0032480(negative regulation of type I interferon production);GO:0032727(positive regulation of interferon-alpha production);GO:0032728(positive regulation of interferon-beta production);GO:0034344(regulation of type III interferon production);GO:0035549(positive regulation of interferon-beta secretion);GO:0039528(cytoplasmic pattern recognition receptor signaling pathway in response to virus);GO:0039530(MDA-5 signaling pathway);GO:0042802(identical protein binding);GO:0043021(ribonucleoprotein complex binding);GO:0045087(innate immune response);GO:0046872(metal ion binding);GO:0051607(defense response to virus);GO:0060760(positive regulation of response to cytokine stimulus);GO:0071360(cellular response to exogenous dsRNA);GO:1902741(positive regulation of interferon-alpha secretion);GO:1904469(positive regulation of tumor necrosis factor secretion);GO:2000778(positive regulation of interleukin-6 secretion)","04622(RIG-I-like receptor signaling pathway);05161(Hepatitis B);05162(Measles);05164(Influenza A);05168(Herpes simplex virus 1 infection)","K12647","EC:3.6.4.13","interferon induced with helicase C domain 1 [Source:HGNC Symbol;Acc:HGNC:18873]",{"v":0.062652,"d":"0.06"},{"v":0.059992,"d":"0.06"},{"v":0.007065,"d":"0.01"},{"v":0.023417,"d":"0.02"},{"v":0.043484,"d":"0.04"},{"v":0.049511,"d":"0.05"},{"v":1.11422361955812,"d":"1.11"},{"v":0.156038803999062,"d":"0.16"},1,1,"up","no"]
[148888,0,"chr4","+",664910,670314,"ENST00000461490",5,549,"ENSG00000133256","PDE6B","GO:0001750(photoreceptor outer segment);GO:0004114(3',5'-cyclic-nucleotide phosphodiesterase activity);GO:0005515(protein binding);GO:0005886(plasma membrane);GO:0007165(signal transduction);GO:0007186(G protein-coupled receptor signaling pathway);GO:0007223(Wnt signaling pathway, calcium modulating pathway);GO:0007601(visual perception);GO:0007603(phototransduction, visible light);GO:0008081(phosphoric diester hydrolase activity);GO:0009583(detection of light stimulus);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016056(rhodopsin mediated signaling pathway);GO:0016787(hydrolase activity);GO:0022400(regulation of rhodopsin mediated signaling pathway);GO:0046872(metal ion binding);GO:0047555(3',5'-cyclic-GMP phosphodiesterase activity);GO:0050896(response to stimulus);GO:0051480(regulation of cytosolic calcium ion concentration);GO:0060041(retina development in camera-type eye);GO:0097381(photoreceptor disc membrane)","00230(Purine metabolism);04744(Phototransduction)","NA","NA","phosphodiesterase 6B [Source:HGNC Symbol;Acc:HGNC:8786]",0,{"v":0.091964,"d":"0.09"},0,0,0,0,"inf","inf",1,1,"up","no"]
[103336,0,"chr19","+",38304273,38305006,"ENST00000591852",3,502,"ENSG00000167644","C19orf33","GO:0005634(nucleus);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0008150(biological_process)","NA","NA","NA","chromosome 19 open reading frame 33 [Source:HGNC Symbol;Acc:HGNC:16668]",{"v":0.054753,"d":"0.05"},0,0,0,0,0,"inf","inf",1,1,"up","no"]
[181770,0,"chr7","-",99670910,99679996,"ENST00000463907",5,1623,"ENSG00000106258","CYP3A5","GO:0002933(lipid hydroxylation);GO:0004497(monooxygenase activity);GO:0005506(iron ion binding);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0006805(xenobiotic metabolic process);GO:0008202(steroid metabolic process);GO:0009822(alkaloid catabolic process);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016491(oxidoreductase activity);GO:0016705(oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen);GO:0016712(oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen);GO:0019825(oxygen binding);GO:0020037(heme binding);GO:0031090(organelle membrane);GO:0042737(drug catabolic process);GO:0043231(intracellular membrane-bounded organelle);GO:0046872(metal ion binding);GO:0055114(oxidation-reduction process);GO:0070330(aromatase activity);GO:0070989(oxidative demethylation);GO:0101020(estrogen 16-alpha-hydroxylase activity)","00140(Steroid hormone biosynthesis);00830(Retinol metabolism);00980(Metabolism of xenobiotics by cytochrome P450);00982(Drug metabolism - cytochrome P450);05204(Chemical carcinogenesis)","NA","NA","cytochrome P450 family 3 subfamily A member 5 [Source:HGNC Symbol;Acc:HGNC:2638]",0,0,0,0,0,0,1,0,1,1,"no","no"]
[178916,0,"chr7","+",48089344,48108419,"ENST00000482015",7,861,"ENSG00000183696","UPP1","GO:0003824(catalytic activity);GO:0004850(uridine phosphorylase activity);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0006139(nucleobase-containing compound metabolic process);GO:0006218(uridine catabolic process);GO:0006220(pyrimidine nucleotide metabolic process);GO:0009116(nucleoside metabolic process);GO:0009166(nucleotide catabolic process);GO:0016740(transferase activity);GO:0016757(transferase activity, transferring glycosyl groups);GO:0016763(transferase activity, transferring pentosyl groups);GO:0042149(cellular response to glucose starvation);GO:0043097(pyrimidine nucleoside salvage);GO:0044206(UMP salvage);GO:0046108(uridine metabolic process);GO:0046135(pyrimidine nucleoside catabolic process)","00240(Pyrimidine metabolism);00983(Drug metabolism - other enzymes)","K00757","EC:2.4.2.3","uridine phosphorylase 1 [Source:HGNC Symbol;Acc:HGNC:12576]",0,{"v":0.205335,"d":"0.21"},0,{"v":0.274928,"d":"0.27"},{"v":0.402216,"d":"0.40"},{"v":0.409693,"d":"0.41"},{"v":0.18892897463005,"d":"0.19"},{"v":-2.40408412079726,"d":"-2.40"},1,1,"down","no"]
[48138,0,"chr12","-",111938047,112013166,"ENST00000550020",5,572,"ENSG00000198270","TMEM116","GO:0003674(molecular_function);GO:0005575(cellular_component);GO:0008150(biological_process);GO:0016020(membrane);GO:0016021(integral component of membrane)","NA","NA","NA","transmembrane protein 116 [Source:HGNC Symbol;Acc:HGNC:25084]",{"v":0.280716,"d":"0.28"},{"v":0.119512,"d":"0.12"},{"v":0.140209,"d":"0.14"},{"v":0.138773,"d":"0.14"},{"v":0.133791,"d":"0.13"},{"v":0.248835,"d":"0.25"},{"v":1.03651330363119,"d":"1.04"},{"v":0.0517386335332658,"d":"0.05"},1,1,"up","no"]
[86550,0,"chr17","+",45135647,45143850,"ENST00000586346",10,1579,"ENSG00000181513","ACBD4","GO:0000062(fatty-acyl-CoA binding);GO:0005515(protein binding);GO:0008289(lipid binding);GO:0016020(membrane);GO:0016021(integral component of membrane)","NA","NA","NA","acyl-CoA binding domain containing 4 [Source:HGNC Symbol;Acc:HGNC:23337]",{"v":0.129396,"d":"0.13"},{"v":0.481233,"d":"0.48"},{"v":0.126276,"d":"0.13"},{"v":0.987886,"d":"0.99"},{"v":0.236382,"d":"0.24"},{"v":0.055404,"d":"0.06"},{"v":0.57585459398971,"d":"0.58"},{"v":-0.796223524560947,"d":"-0.80"},1,1,"down","no"]
[97722,0,"chr19","+",5914272,5915130,"ENST00000585541",2,784,"ENSG00000105519","CAPS","GO:0005509(calcium ion binding);GO:0005737(cytoplasm);GO:0031982(vesicle);GO:0035556(intracellular signal transduction);GO:0046872(metal ion binding)","NA","NA","NA","calcyphosine [Source:HGNC Symbol;Acc:HGNC:1487]",{"v":0.134049,"d":"0.13"},{"v":0.017131,"d":"0.02"},{"v":0.099559,"d":"0.10"},{"v":0.045478,"d":"0.05"},{"v":0.419314,"d":"0.42"},{"v":0.125149,"d":"0.13"},{"v":0.425023858318035,"d":"0.43"},{"v":-1.23438426702286,"d":"-1.23"},1,1,"down","no"]
[46220,0,"chr12","+",82686880,82986573,"ENST00000551915",8,3304,"ENSG00000179104","TMTC2","GO:0000030(mannosyltransferase activity);GO:0004169(dolichyl-phosphate-mannose-protein mannosyltransferase activity);GO:0005515(protein binding);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0006486(protein glycosylation);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016740(transferase activity);GO:0035269(protein O-linked mannosylation);GO:0055074(calcium ion homeostasis)","NA","NA","NA","transmembrane and tetratricopeptide repeat containing 2 [Source:HGNC Symbol;Acc:HGNC:25440]",{"v":0.109002,"d":"0.11"},{"v":0.055443,"d":"0.06"},{"v":0.087693,"d":"0.09"},0,{"v":0.000282,"d":"0.00"},{"v":0.005972,"d":"0.01"},{"v":40.3162775823473,"d":"40.32"},{"v":5.33329053527773,"d":"5.33"},1,1,"up","no"]
[6357,0,"chr1","-",53087179,53142604,"ENST00000611397",10,2471,"ENSG00000162383","SLC1A7","GO:0001504(neurotransmitter uptake);GO:0005313(L-glutamate transmembrane transporter activity);GO:0005886(plasma membrane);GO:0006811(ion transport);GO:0006835(dicarboxylic acid transport);GO:0014047(glutamate secretion);GO:0015293(symporter activity);GO:0015813(L-glutamate transmembrane transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0055085(transmembrane transport);GO:0098793(presynapse);GO:0098810(neurotransmitter reuptake)","04721(Synaptic vesicle cycle);04724(Glutamatergic synapse)","NA","NA","solute carrier family 1 member 7 [Source:HGNC Symbol;Acc:HGNC:10945]",0,0,0.03,0,{"v":0.057481,"d":"0.06"},0,{"v":0.521911588176963,"d":"0.52"},{"v":-0.938122659934418,"d":"-0.94"},1,1,"down","no"]
[122377,0,"chr2","-",219289625,219292896,"ENST00000460801",4,2239,"ENSG00000054356","PTPRN","GO:0000302(response to reactive oxygen species);GO:0001553(luteinization);GO:0004725(protein tyrosine phosphatase activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005768(endosome);GO:0005794(Golgi apparatus);GO:0005886(plasma membrane);GO:0006470(protein dephosphorylation);GO:0008134(transcription factor binding);GO:0009749(response to glucose);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016311(dephosphorylation);GO:0016787(hydrolase activity);GO:0016791(phosphatase activity);GO:0019221(cytokine-mediated signaling pathway);GO:0030054(cell junction);GO:0030073(insulin secretion);GO:0030141(secretory granule);GO:0030424(axon);GO:0030507(spectrin binding);GO:0030658(transport vesicle membrane);GO:0031410(cytoplasmic vesicle);GO:0032868(response to insulin);GO:0035335(peptidyl-tyrosine dephosphorylation);GO:0035773(insulin secretion involved in cellular response to glucose stimulus);GO:0042995(cell projection);GO:0043025(neuronal cell body);GO:0043204(perikaryon);GO:0043627(response to estrogen);GO:0043679(axon terminus);GO:0044389(ubiquitin-like protein ligase binding);GO:0045202(synapse);GO:0045944(positive regulation of transcription by RNA polymerase II);GO:0051020(GTPase binding);GO:0051591(response to cAMP);GO:1904692(positive regulation of type B pancreatic cell proliferation);GO:1990502(dense core granule maturation)","04940(Type I diabetes mellitus)","K07817","EC:3.1.3.48","protein tyrosine phosphatase, receptor type N [Source:HGNC Symbol;Acc:HGNC:9676]",{"v":0.186778,"d":"0.19"},{"v":0.16414,"d":"0.16"},{"v":0.118979,"d":"0.12"},{"v":0.034121,"d":"0.03"},{"v":0.07557,"d":"0.08"},{"v":0.060107,"d":"0.06"},{"v":2.76738830846064,"d":"2.77"},{"v":1.46852509114174,"d":"1.47"},1,1,"up","no"]
[161352,0,"chr5","+",100401441,100408899,"ENST00000511468",3,563,"ENSG00000249787","AC113385","NA","NA","NA","NA","novel transcript",0,0,0,0,0,0,1,0,1,1,"no","no"]
[124971,0,"chr20","+",8765260,8968319,"ENST00000635929",10,2291,"ENSG00000182621","PLCB1","GO:0000086(G2/M transition of mitotic cell cycle);GO:0000790(nuclear chromatin);GO:0004435(phosphatidylinositol phospholipase C activity);GO:0004629(phospholipase C activity);GO:0005096(GTPase activator activity);GO:0005509(calcium ion binding);GO:0005515(protein binding);GO:0005516(calmodulin binding);GO:0005521(lamin binding);GO:0005546(phosphatidylinositol-4,5-bisphosphate binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0006629(lipid metabolic process);GO:0007165(signal transduction);GO:0007186(G protein-coupled receptor signaling pathway);GO:0007213(G protein-coupled acetylcholine receptor signaling pathway);GO:0007215(glutamate receptor signaling pathway);GO:0007223(Wnt signaling pathway, calcium modulating pathway);GO:0007420(brain development);GO:0007613(memory);GO:0008081(phosphoric diester hydrolase activity);GO:0008277(regulation of G protein-coupled receptor signaling pathway);GO:0016020(membrane);GO:0016042(lipid catabolic process);GO:0016607(nuclear speck);GO:0016787(hydrolase activity);GO:0019899(enzyme binding);GO:0021987(cerebral cortex development);GO:0031965(nuclear membrane);GO:0032735(positive regulation of interleukin-12 production);GO:0032959(inositol trisphosphate biosynthetic process);GO:0032991(protein-containing complex);GO:0035556(intracellular signal transduction);GO:0035722(interleukin-12-mediated signaling pathway);GO:0035723(interleukin-15-mediated signaling pathway);GO:0040019(positive regulation of embryonic development);GO:0042803(protein homodimerization activity);GO:0043547(positive regulation of GTPase activity);GO:0043647(inositol phosphate metabolic process);GO:0045444(fat cell differentiation);GO:0045663(positive regulation of myoblast differentiation);GO:0045892(negative regulation of transcription, DNA-templated);GO:0045893(positive regulation of transcription, DNA-templated);GO:0046330(positive regulation of JNK cascade);GO:0046488(phosphatidylinositol metabolic process);GO:0048009(insulin-like growth factor receptor signaling pathway);GO:0048015(phosphatidylinositol-mediated signaling);GO:0048639(positive regulation of developmental growth);GO:0051209(release of sequestered calcium ion into cytosol);GO:0051726(regulation of cell cycle);GO:0060466(activation of meiosis involved in egg activation);GO:0070062(extracellular exosome);GO:0070498(interleukin-1-mediated signaling pathway);GO:0080154(regulation of fertilization);GO:0098794(postsynapse);GO:0098978(glutamatergic synapse);GO:0098982(GABA-ergic synapse);GO:0099170(postsynaptic modulation of chemical synaptic transmission);GO:0099178(regulation of retrograde trans-synaptic signaling by endocanabinoid);GO:1900087(positive regulation of G1/S transition of mitotic cell cycle);GO:2000344(positive regulation of acrosome reaction);GO:2000438(negative regulation of monocyte extravasation);GO:2000560(positive regulation of CD24 biosynthetic process)","00562(Inositol phosphate metabolism);04015(Rap1 signaling pathway);04020(Calcium signaling pathway);04022(cGMP-PKG signaling pathway);04062(Chemokine signaling pathway);04070(Phosphatidylinositol signaling system);04071(Sphingolipid signaling pathway);04072(Phospholipase D signaling pathway);04261(Adrenergic signaling in cardiomyocytes);04270(Vascular smooth muscle contraction);04310(Wnt signaling pathway);04371(Apelin signaling pathway);04540(Gap junction);04611(Platelet activation);04621(NOD-like receptor signaling pathway);04713(Circadian entrainment);04720(Long-term potentiation);04723(Retrograde endocannabinoid signaling);04724(Glutamatergic synapse);04725(Cholinergic synapse);04726(Serotonergic synapse);04728(Dopaminergic synapse);04730(Long-term depression);04750(Inflammatory mediator regulation of TRP channels);04911(Insulin secretion);04912(GnRH signaling pathway);04915(Estrogen signaling pathway);04916(Melanogenesis);04918(Thyroid hormone synthesis);04919(Thyroid hormone signaling pathway);04921(Oxytocin signaling pathway);04922(Glucagon signaling pathway);04924(Renin secretion);04925(Aldosterone synthesis and secretion);04926(Relaxin signaling pathway);04927(Cortisol synthesis and secretion);04928(Parathyroid hormone synthesis, secretion and action);04933(AGE-RAGE signaling pathway in diabetic complications);04934(Cushing syndrome);04961(Endocrine and other factor-regulated calcium reabsorption);04970(Salivary secretion);04971(Gastric acid secretion);04972(Pancreatic secretion);05010(Alzheimer disease);05016(Huntington disease);05142(Chagas disease (American trypanosomiasis));05143(African trypanosomiasis);05146(Amoebiasis);05163(Human cytomegalovirus infection);05200(Pathways in cancer)","K05858","EC:3.1.4.11","phospholipase C beta 1 [Source:HGNC Symbol;Acc:HGNC:15917]",0,{"v":0.027265,"d":"0.03"},0,0,0,0,"inf","inf",1,1,"up","no"]
[2867,0,"chr1","+",24643288,24648887,"ENST00000600523",6,575,"ENSG00000133226","SRRM1","GO:0000375(RNA splicing, via transesterification reactions);GO:0000398(mRNA splicing, via spliceosome);GO:0003677(DNA binding);GO:0003723(RNA binding);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005681(spliceosomal complex);GO:0005829(cytosol);GO:0006397(mRNA processing);GO:0006405(RNA export from nucleus);GO:0006406(mRNA export from nucleus);GO:0008380(RNA splicing);GO:0016363(nuclear matrix);GO:0016607(nuclear speck);GO:0031124(mRNA 3'-end processing);GO:0071013(catalytic step 2 spliceosome)","03013(RNA transport);03015(mRNA surveillance pathway)","K13171","NA","serine and arginine repetitive matrix 1 [Source:HGNC Symbol;Acc:HGNC:16638]",0,0,0,{"v":0.367149,"d":"0.37"},0,0,"-inf","-inf",1,1,"down","no"]
[124449,0,"chr20","-",1309975,1313639,"ENST00000381808",5,1261,"ENSG00000125775","SDCBP2","GO:0005515(protein binding);GO:0005546(phosphatidylinositol-4,5-bisphosphate binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005730(nucleolus);GO:0005737(cytoplasm);GO:0005886(plasma membrane);GO:0007399(nervous system development);GO:0008022(protein C-terminus binding);GO:0008283(cell population proliferation);GO:0008289(lipid binding);GO:0016020(membrane);GO:0016607(nuclear speck);GO:0035556(intracellular signal transduction);GO:0042802(identical protein binding);GO:0042803(protein homodimerization activity);GO:0046907(intracellular transport);GO:0046982(protein heterodimerization activity);GO:0070062(extracellular exosome)","NA","NA","NA","syndecan binding protein 2 [Source:HGNC Symbol;Acc:HGNC:15756]",{"v":0.4797,"d":"0.48"},{"v":0.211037,"d":"0.21"},{"v":0.581411,"d":"0.58"},{"v":0.4399,"d":"0.44"},{"v":0.349381,"d":"0.35"},{"v":0.690048,"d":"0.69"},{"v":0.859949341897577,"d":"0.86"},{"v":-0.217676419195575,"d":"-0.22"},1,1,"down","no"]
[25180,0,"chr10","-",125807150,125823089,"ENST00000368774",6,744,"ENSG00000188690","UROS","GO:0004852(uroporphyrinogen-III synthase activity);GO:0005739(mitochondrion);GO:0005829(cytosol);GO:0006779(porphyrin-containing compound biosynthetic process);GO:0006780(uroporphyrinogen III biosynthetic process);GO:0006782(protoporphyrinogen IX biosynthetic process);GO:0006783(heme biosynthetic process);GO:0016829(lyase activity);GO:0033014(tetrapyrrole biosynthetic process);GO:0046677(response to antibiotic);GO:0048037(cofactor binding);GO:0070541(response to platinum ion);GO:0071243(cellular response to arsenic-containing substance);GO:0071418(cellular response to amine stimulus)","00860(Porphyrin and chlorophyll metabolism)","K01719","EC:4.2.1.75","uroporphyrinogen III synthase [Source:HGNC Symbol;Acc:HGNC:12592]",{"v":0.115171,"d":"0.12"},{"v":0.196101,"d":"0.20"},{"v":0.310176,"d":"0.31"},{"v":0.280559,"d":"0.28"},{"v":0.524758,"d":"0.52"},{"v":0.292513,"d":"0.29"},{"v":0.566069427871346,"d":"0.57"},{"v":-0.820949085817879,"d":"-0.82"},1,1,"down","no"]
[24350,0,"chr10","+",110910596,110912244,"ENST00000603915",1,1649,"ENSG00000270589","AL158163","NA","NA","NA","NA","novel transcript, antisense to BBIP1",{"v":0.076393,"d":"0.08"},{"v":0.277382,"d":"0.28"},{"v":0.316559,"d":"0.32"},{"v":0.116646,"d":"0.12"},{"v":0.204375,"d":"0.20"},{"v":0.127395,"d":"0.13"},{"v":1.49489313494612,"d":"1.49"},{"v":0.580042354527841,"d":"0.58"},1,1,"up","no"]
[85081,0,"chr17","-",39904812,39917316,"ENST00000524039",7,1100,"ENSG00000073605","GSDMB","GO:0001786(phosphatidylserine binding);GO:0003674(molecular_function);GO:0005546(phosphatidylinositol-4,5-bisphosphate binding);GO:0005575(cellular_component);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0008150(biological_process);GO:0012501(programmed cell death);GO:0016020(membrane);GO:0070269(pyroptosis);GO:0070273(phosphatidylinositol-4-phosphate binding)","NA","K22142","NA","gasdermin B [Source:HGNC Symbol;Acc:HGNC:23690]",{"v":0.38457,"d":"0.38"},{"v":0.483384,"d":"0.48"},{"v":0.298924,"d":"0.30"},{"v":0.444284,"d":"0.44"},0,{"v":0.253916,"d":"0.25"},{"v":1.67126611286164,"d":"1.67"},{"v":0.74094146956831,"d":"0.74"},1,1,"up","no"]
[132878,0,"chr22","+",24648246,24653356,"ENST00000614808",3,601,"ENSG00000284128","AP000356","NA","NA","NA","NA","breakpoint cluster region pseudogene 3",0,0,0,0,0,0,1,0,1,1,"no","no"]
[5120,0,"chr1","+",43317930,43319482,"ENST00000492599",2,391,"ENSG00000066056","TIE1","GO:0000166(nucleotide binding);GO:0001525(angiogenesis);GO:0001568(blood vessel development);GO:0001570(vasculogenesis);GO:0001701(in utero embryonic development);GO:0004672(protein kinase activity);GO:0004713(protein tyrosine kinase activity);GO:0004714(transmembrane receptor protein tyrosine kinase activity);GO:0005515(protein binding);GO:0005524(ATP binding);GO:0005886(plasma membrane);GO:0005887(integral component of plasma membrane);GO:0006468(protein phosphorylation);GO:0007165(signal transduction);GO:0007169(transmembrane receptor protein tyrosine kinase signaling pathway);GO:0007498(mesoderm development);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0016525(negative regulation of angiogenesis);GO:0016740(transferase activity);GO:0018108(peptidyl-tyrosine phosphorylation);GO:0030336(negative regulation of cell migration);GO:0032526(response to retinoic acid);GO:0043235(receptor complex);GO:0045026(plasma membrane fusion);GO:0045766(positive regulation of angiogenesis)","NA","K05120","EC:2.7.10.1","tyrosine kinase with immunoglobulin like and EGF like domains 1 [Source:HGNC Symbol;Acc:HGNC:11809]",0,0,0,0,0,0,1,0,1,1,"no","no"]
[10138,0,"chr1","+",120805418,120840619,"ENST00000611702",14,1831,"ENSG00000273136","NBPF26","GO:0005509(calcium ion binding)","NA","NA","NA","NBPF member 26 [Source:HGNC Symbol;Acc:HGNC:49571]",{"v":0.001115,"d":"0.00"},0,{"v":0.003279,"d":"0.00"},0,0,0,"inf","inf",1,1,"up","no"]
[127852,0,"chr20","-",52110344,52111049,"ENST00000442902",1,706,"ENSG00000233347","ERP29P1","NA","NA","NA","NA","endoplasmic reticulum lumenal protein 29 pseudogene 1 [Source:HGNC Symbol;Acc:HGNC:24625]",{"v":0.058,"d":"0.06"},{"v":0.048188,"d":"0.05"},0,0,0,{"v":0.053898,"d":"0.05"},{"v":1.97016586886341,"d":"1.97"},{"v":0.978317095728911,"d":"0.98"},1,1,"up","no"]
[63197,0,"chr15","+",41832429,41834920,"ENST00000562035",2,265,"ENSG00000243789","JMJD7","GO:0004175(endopeptidase activity);GO:0004177(aminopeptidase activity);GO:0004497(monooxygenase activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0006508(proteolysis);GO:0008233(peptidase activity);GO:0016491(oxidoreductase activity);GO:0016706(2-oxoglutarate-dependent dioxygenase activity);GO:0016787(hydrolase activity);GO:0018126(protein hydroxylation);GO:0035064(methylated histone binding);GO:0046872(metal ion binding);GO:0055114(oxidation-reduction process)","NA","K19219","NA","jumonji domain containing 7 [Source:HGNC Symbol;Acc:HGNC:34397]",0,0,{"v":0.03589,"d":"0.04"},0,0,0,"inf","inf",1,1,"up","no"]
[134698,0,"chr22","+",38706511,38716669,"ENST00000488787",4,582,"ENSG00000100226","GTPBP1","GO:0000166(nucleotide binding);GO:0000177(cytoplasmic exosome (RNase complex));GO:0003723(RNA binding);GO:0003746(translation elongation factor activity);GO:0003924(GTPase activity);GO:0005525(GTP binding);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0006414(translational elongation);GO:0006955(immune response);GO:0007165(signal transduction);GO:0016020(membrane);GO:0046039(GTP metabolic process);GO:0061014(positive regulation of mRNA catabolic process)","NA","NA","NA","GTP binding protein 1 [Source:HGNC Symbol;Acc:HGNC:4669]",0,{"v":0.037808,"d":"0.04"},0,0,0,0,"inf","inf",1,1,"up","no"]
[68165,0,"chr15","+",90227239,90228062,"ENST00000561321",2,563,"ENSG00000185033","SEMA4B","GO:0005515(protein binding);GO:0005886(plasma membrane);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0045202(synapse)","04360(Axon guidance)","K06521","NA","semaphorin 4B [Source:HGNC Symbol;Acc:HGNC:10730]",{"v":0.042983,"d":"0.04"},{"v":0.004044,"d":"0.00"},{"v":0.045904,"d":"0.05"},{"v":0.001859,"d":"0.00"},{"v":0.083239,"d":"0.08"},{"v":0.073092,"d":"0.07"},{"v":0.587464441494405,"d":"0.59"},{"v":-0.767426565136903,"d":"-0.77"},1,1,"down","no"]
[9490,0,"chr1","+",111473869,111478472,"ENST00000369718",6,915,"ENSG00000143110","C1orf162","GO:0016020(membrane);GO:0016021(integral component of membrane)","NA","NA","NA","chromosome 1 open reading frame 162 [Source:HGNC Symbol;Acc:HGNC:28344]",0,0,0,0,0,0,1,0,1,1,"no","no"]
[167756,0,"chr6","+",21954422,22195127,"ENST00000651007",7,1967,"ENSG00000272168","CASC15","NA","NA","NA","NA","cancer susceptibility 15 [Source:HGNC Symbol;Acc:HGNC:28245]",{"v":0.00182,"d":"0.00"},{"v":0.036269,"d":"0.04"},0,0,0,0,"inf","inf",1,1,"up","no"]
[167632,0,"chr6","+",17282701,17293866,"ENST00000318204",3,2394,"ENSG00000112183","RBM24","GO:0000381(regulation of alternative mRNA splicing, via spliceosome);GO:0003197(endocardial cushion development);GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0003729(mRNA binding);GO:0003730(mRNA 3'-UTR binding);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0006397(mRNA processing);GO:0006417(regulation of translation);GO:0006974(cellular response to DNA damage stimulus);GO:0008380(RNA splicing);GO:0010830(regulation of myotube differentiation);GO:0010831(positive regulation of myotube differentiation);GO:0030154(cell differentiation);GO:0035925(mRNA 3'-UTR AU-rich region binding);GO:0043488(regulation of mRNA stability);GO:0045663(positive regulation of myoblast differentiation);GO:0048255(mRNA stabilization);GO:0061157(mRNA destabilization);GO:0061158(3'-UTR-mediated mRNA destabilization);GO:0097157(pre-mRNA intronic binding);GO:1902811(positive regulation of skeletal muscle fiber differentiation);GO:1905870(positive regulation of 3'-UTR-mediated mRNA stabilization);GO:1990715(mRNA CDS binding);GO:1990825(sequence-specific mRNA binding);GO:1990904(ribonucleoprotein complex);GO:2000738(positive regulation of stem cell differentiation);GO:2000766(negative regulation of cytoplasmic translation)","NA","NA","NA","RNA binding motif protein 24 [Source:HGNC Symbol;Acc:HGNC:21539]",0,{"v":0.005798,"d":"0.01"},{"v":0.110082,"d":"0.11"},{"v":0.079839,"d":"0.08"},{"v":0.028968,"d":"0.03"},{"v":0.064431,"d":"0.06"},{"v":0.668906360036482,"d":"0.67"},{"v":-0.580123832251463,"d":"-0.58"},1,1,"down","no"]
[175701,0,"chr6","+",166999317,167042418,"ENST00000622353",11,3451,"ENSG00000213066","FGFR1OP","GO:0000086(G2/M transition of mitotic cell cycle);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005813(centrosome);GO:0005814(centriole);GO:0005815(microtubule organizing center);GO:0005829(cytosol);GO:0005856(cytoskeleton);GO:0006469(negative regulation of protein kinase activity);GO:0008284(positive regulation of cell population proliferation);GO:0010389(regulation of G2/M transition of mitotic cell cycle);GO:0019901(protein kinase binding);GO:0030030(cell projection organization);GO:0030292(protein tyrosine kinase inhibitor activity);GO:0030307(positive regulation of cell growth);GO:0030335(positive regulation of cell migration);GO:0034453(microtubule anchoring);GO:0042803(protein homodimerization activity);GO:0042995(cell projection);GO:0048471(perinuclear region of cytoplasm);GO:0061099(negative regulation of protein tyrosine kinase activity);GO:0097711(ciliary basal body-plasma membrane docking)","NA","K16546","NA","FGFR1 oncogene partner [Source:HGNC Symbol;Acc:HGNC:17012]",{"v":0.110421,"d":"0.11"},{"v":0.040247,"d":"0.04"},{"v":0.144245,"d":"0.14"},{"v":0.138222,"d":"0.14"},{"v":0.151189,"d":"0.15"},{"v":0.009932,"d":"0.01"},{"v":0.985200923355482,"d":"0.99"},{"v":-0.0215101149191949,"d":"-0.02"},1,1,"down","no"]
[193423,0,"chr8","+",143553707,143559479,"ENST00000529854",5,511,"ENSG00000104518","GSDMD","GO:0001786(phosphatidylserine binding);GO:0002376(immune system process);GO:0005515(protein binding);GO:0005546(phosphatidylinositol-4,5-bisphosphate binding);GO:0005576(extracellular region);GO:0005615(extracellular space);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0006954(inflammatory response);GO:0012501(programmed cell death);GO:0016020(membrane);GO:0019835(cytolysis);GO:0031668(cellular response to extracellular stimulus);GO:0035580(specific granule lumen);GO:0035915(pore formation in membrane of other organism);GO:0043312(neutrophil degranulation);GO:0045087(innate immune response);GO:0046931(pore complex assembly);GO:0050718(positive regulation of interleukin-1 beta secretion);GO:0050829(defense response to Gram-negative bacterium);GO:0050830(defense response to Gram-positive bacterium);GO:0051260(protein homooligomerization);GO:0061702(inflammasome complex);GO:0070269(pyroptosis);GO:0070273(phosphatidylinositol-4-phosphate binding);GO:0070300(phosphatidic acid binding);GO:0072559(NLRP3 inflammasome complex);GO:1901612(cardiolipin binding);GO:1904724(tertiary granule lumen);GO:1904813(ficolin-1-rich granule lumen)","04621(NOD-like receptor signaling pathway)","K20917","NA","gasdermin D [Source:HGNC Symbol;Acc:HGNC:25697]",{"v":0.370805,"d":"0.37"},{"v":0.675894,"d":"0.68"},{"v":0.447079,"d":"0.45"},{"v":0.331315,"d":"0.33"},{"v":0.201508,"d":"0.20"},0,{"v":2.80351636472149,"d":"2.80"},{"v":1.48723749114671,"d":"1.49"},1,1,"up","no"]
[54909,0,"chr14","-",23563619,23564799,"ENST00000554977",5,569,"ENSG00000213983","AP1G2","GO:0000139(Golgi membrane);GO:0005515(protein binding);GO:0005623(cell);GO:0005768(endosome);GO:0005794(Golgi apparatus);GO:0005798(Golgi-associated vesicle);GO:0006886(intracellular protein transport);GO:0010008(endosome membrane);GO:0015031(protein transport);GO:0016020(membrane);GO:0016032(viral process);GO:0016192(vesicle-mediated transport);GO:0030117(membrane coat);GO:0030121(AP-1 adaptor complex);GO:0030133(transport vesicle);GO:0030659(cytoplasmic vesicle membrane);GO:0031410(cytoplasmic vesicle)","04142(Lysosome);05170(Human immunodeficiency virus 1 infection)","K12391","NA","adaptor related protein complex 1 subunit gamma 2 [Source:HGNC Symbol;Acc:HGNC:556]",{"v":0.439935,"d":"0.44"},{"v":0.475552,"d":"0.48"},{"v":0.433576,"d":"0.43"},{"v":0.292356,"d":"0.29"},{"v":0.517326,"d":"0.52"},{"v":0.70843,"d":"0.71"},{"v":0.888645238295989,"d":"0.89"},{"v":-0.170320508340225,"d":"-0.17"},1,1,"down","no"]
[137817,0,"chr3","+",27802762,27860327,"ENST00000425195",4,493,"ENSG00000225548","LINC01980","NA","NA","NA","NA","long intergenic non-protein coding RNA 1980 [Source:HGNC Symbol;Acc:HGNC:52808]",0,0,0,0,0,0,1,0,1,1,"no","no"]
[165698,0,"chr5","+",176238367,176345985,"ENST00000341199",9,2056,"ENSG00000170085","SIMC1","GO:0032184(SUMO polymer binding)","NA","NA","NA","SUMO interacting motifs containing 1 [Source:HGNC Symbol;Acc:HGNC:24779]",{"v":0.350254,"d":"0.35"},0,0,0,{"v":0.000583,"d":"0.00"},{"v":0.506687,"d":"0.51"},{"v":0.690468586748674,"d":"0.69"},{"v":-0.534352315122086,"d":"-0.53"},1,1,"down","no"]
[172492,0,"chr6","+",89673469,89675783,"ENST00000438877",2,472,"ENSG00000228124","AL096678","NA","NA","NA","NA","novel transcript",0,0,0,0,0,0,1,0,1,1,"no","no"]
[195731,0,"chr9","+",36572897,36607622,"ENST00000489766",6,551,"ENSG00000165304","MELK","GO:0000086(G2/M transition of mitotic cell cycle);GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0004715(non-membrane spanning protein tyrosine kinase activity);GO:0005509(calcium ion binding);GO:0005515(protein binding);GO:0005524(ATP binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005886(plasma membrane);GO:0005938(cell cortex);GO:0006468(protein phosphorylation);GO:0006915(apoptotic process);GO:0007049(cell cycle);GO:0008283(cell population proliferation);GO:0008289(lipid binding);GO:0008631(intrinsic apoptotic signaling pathway in response to oxidative stress);GO:0016020(membrane);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0016740(transferase activity);GO:0018108(peptidyl-tyrosine phosphorylation);GO:0030097(hemopoiesis);GO:0035556(intracellular signal transduction);GO:0043065(positive regulation of apoptotic process);GO:0046777(protein autophosphorylation);GO:0061351(neural precursor cell proliferation)","NA","K08799","EC:2.7.11.1","maternal embryonic leucine zipper kinase [Source:HGNC Symbol;Acc:HGNC:16870]",0,0,0,0,0,0,1,0,1,1,"no","no"]
[70978,0,"chr16","-",4608883,4615027,"ENST00000591897",3,1275,"ENSG00000153443","UBALD1","GO:0005515(protein binding)","NA","NA","NA","UBA like domain containing 1 [Source:HGNC Symbol;Acc:HGNC:29576]",{"v":0.21389,"d":"0.21"},{"v":0.232371,"d":"0.23"},{"v":0.035806,"d":"0.04"},{"v":0.292207,"d":"0.29"},{"v":0.268472,"d":"0.27"},{"v":0.12142,"d":"0.12"},{"v":0.706740517139008,"d":"0.71"},{"v":-0.500747474408994,"d":"-0.50"},1,1,"down","no"]
[77461,0,"chr16","+",72805998,72809872,"ENST00000620814",2,561,"ENSG00000259209","AC004943","NA","NA","NA","NA","novel transcript, antisense to ZFHX3",0,0,0,0,0,{"v":0.158082,"d":"0.16"},"-inf","-inf",1,1,"down","no"]
[185459,0,"chr7","-",151081484,151083400,"ENST00000482202",3,899,"ENSG00000164897","TMUB1","GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005730(nucleolus);GO:0005737(cytoplasm);GO:0005768(endosome);GO:0005815(microtubule organizing center);GO:0005829(cytosol);GO:0005856(cytoskeleton);GO:0005886(plasma membrane);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0030054(cell junction);GO:0030433(ubiquitin-dependent ERAD pathway);GO:0045202(synapse);GO:0045211(postsynaptic membrane);GO:0055037(recycling endosome)","NA","NA","NA","transmembrane and ubiquitin like domain containing 1 [Source:HGNC Symbol;Acc:HGNC:21709]",0,{"v":0.631435,"d":"0.63"},{"v":0.427851,"d":"0.43"},{"v":0.145609,"d":"0.15"},{"v":0.021993,"d":"0.02"},{"v":0.030593,"d":"0.03"},{"v":5.34466560710411,"d":"5.34"},{"v":2.41809968750349,"d":"2.42"},1,1,"up","no"]
[144735,0,"chr3","+",138349262,138402362,"ENST00000474559",6,856,"ENSG00000158186","MRAS","GO:0000166(nucleotide binding);GO:0003924(GTPase activity);GO:0005515(protein binding);GO:0005525(GTP binding);GO:0005886(plasma membrane);GO:0007165(signal transduction);GO:0007265(Ras protein signal transduction);GO:0007275(multicellular organism development);GO:0007517(muscle organ development);GO:0016020(membrane);GO:0030036(actin cytoskeleton organization);GO:0030742(GTP-dependent protein binding);GO:1990830(cellular response to leukemia inhibitory factor)","04010(MAPK signaling pathway);04014(Ras signaling pathway);04015(Rap1 signaling pathway);04072(Phospholipase D signaling pathway);04137(Mitophagy - animal);04140(Autophagy - animal);04218(Cellular senescence);04371(Apelin signaling pathway);04625(C-type lectin receptor signaling pathway);04810(Regulation of actin cytoskeleton);05205(Proteoglycans in cancer)","K07831","NA","muscle RAS oncogene homolog [Source:HGNC Symbol;Acc:HGNC:7227]",0,{"v":0.274181,"d":"0.27"},0,0,{"v":0.261772,"d":"0.26"},0,{"v":1.04740384762312,"d":"1.05"},{"v":0.0668178096293288,"d":"0.07"},1,1,"up","no"]
[143893,0,"chr3","-",127571232,127571838,"ENST00000634543",1,607,"ENSG00000282860","AC084035","NA","NA","NA","NA","novel transcript",{"v":0.097585,"d":"0.10"},{"v":0.375915,"d":"0.38"},{"v":0.291782,"d":"0.29"},{"v":0.133563,"d":"0.13"},0,{"v":0.256448,"d":"0.26"},{"v":1.96220619418427,"d":"1.96"},{"v":0.972476652004032,"d":"0.97"},1,1,"up","no"]
[150764,0,"chr4","+",39459102,39467324,"ENST00000638837",5,1757,"ENSG00000121897","LIAS","GO:0001843(neural tube closure);GO:0003824(catalytic activity);GO:0005739(mitochondrion);GO:0005759(mitochondrial matrix);GO:0006954(inflammatory response);GO:0006979(response to oxidative stress);GO:0009107(lipoate biosynthetic process);GO:0009249(protein lipoylation);GO:0016740(transferase activity);GO:0016783(sulfurtransferase activity);GO:0016992(lipoate synthase activity);GO:0032496(response to lipopolysaccharide);GO:0034641(cellular nitrogen compound metabolic process);GO:0046872(metal ion binding);GO:0051536(iron-sulfur cluster binding);GO:0051539(4 iron, 4 sulfur cluster binding)","00785(Lipoic acid metabolism)","K03644","EC:2.8.1.8","lipoic acid synthetase [Source:HGNC Symbol;Acc:HGNC:16429]",{"v":0.113902,"d":"0.11"},{"v":0.16343,"d":"0.16"},{"v":0.123947,"d":"0.12"},{"v":0.117962,"d":"0.12"},{"v":0.058947,"d":"0.06"},{"v":0.152878,"d":"0.15"},{"v":1.21678234739392,"d":"1.22"},{"v":0.28307112826711,"d":"0.28"},1,1,"up","no"]
[93840,0,"chr18","+",31318160,31359246,"ENST00000257192",15,7191,"ENSG00000134760","DSG1","GO:0001533(cornified envelope);GO:0005509(calcium ion binding);GO:0005515(protein binding);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0005911(cell-cell junction);GO:0007043(cell-cell junction assembly);GO:0007155(cell adhesion);GO:0007156(homophilic cell adhesion via plasma membrane adhesion molecules);GO:0009898(cytoplasmic side of plasma membrane);GO:0015643(toxic substance binding);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016324(apical plasma membrane);GO:0016328(lateral plasma membrane);GO:0016339(calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules);GO:0030054(cell junction);GO:0030057(desmosome);GO:0031424(keratinization);GO:0032570(response to progesterone);GO:0043312(neutrophil degranulation);GO:0045295(gamma-catenin binding);GO:0046872(metal ion binding);GO:0050821(protein stabilization);GO:0060135(maternal process involved in female pregnancy);GO:0070268(cornification);GO:0098609(cell-cell adhesion);GO:0101003(ficolin-1-rich granule membrane)","05150(Staphylococcus aureus infection)","K07596","NA","desmoglein 1 [Source:HGNC Symbol;Acc:HGNC:3048]",0,0,{"v":0.012185,"d":"0.01"},0,0,0,"inf","inf",1,1,"up","no"]
[160401,0,"chr5","+",79612575,79619764,"ENST00000508620",4,483,"ENSG00000164329","TENT2","GO:0000166(nucleotide binding);GO:0002244(hematopoietic progenitor cell differentiation);GO:0004652(polynucleotide adenylyltransferase activity);GO:0005515(protein binding);GO:0005524(ATP binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0006397(mRNA processing);GO:0016740(transferase activity);GO:0021766(hippocampus development);GO:0030182(neuron differentiation);GO:0031380(nuclear RNA-directed RNA polymerase complex);GO:0034062(5'-3' RNA polymerase activity);GO:0043489(RNA stabilization);GO:0043631(RNA polyadenylation);GO:0046872(metal ion binding);GO:0060041(retina development in camera-type eye);GO:0070566(adenylyltransferase activity);GO:0071044(histone mRNA catabolic process);GO:1990603(dark adaptation);GO:2000626(negative regulation of miRNA catabolic process)","NA","K14079","EC:2.7.7.19","terminal nucleotidyltransferase 2 [Source:HGNC Symbol;Acc:HGNC:26776]",{"v":0.082349,"d":"0.08"},0,0,{"v":0.050936,"d":"0.05"},0,0,{"v":1.6167150934506,"d":"1.62"},{"v":0.693065461445409,"d":"0.69"},1,1,"up","no"]
[139920,0,"chr3","+",49412417,49413133,"ENST00000497786",2,587,"ENSG00000145022","TCTA","GO:0003674(molecular_function);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0045671(negative regulation of osteoclast differentiation);GO:0072675(osteoclast fusion)","NA","NA","NA","T cell leukemia translocation altered [Source:HGNC Symbol;Acc:HGNC:11692]",{"v":0.121779,"d":"0.12"},0,{"v":0.210433,"d":"0.21"},0,{"v":0.056106,"d":"0.06"},{"v":0.000156,"d":"0.00"},{"v":5.90473143507163,"d":"5.90"},{"v":2.56187144300913,"d":"2.56"},1,1,"up","no"]
[73466,0,"chr16","+",29812262,29815679,"ENST00000637403",4,2033,"ENSG00000167371","PRRT2","GO:0005886(plasma membrane);GO:0008021(synaptic vesicle);GO:0014069(postsynaptic density);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0017075(syntaxin-1 binding);GO:0030054(cell junction);GO:0030424(axon);GO:0030672(synaptic vesicle membrane);GO:0031410(cytoplasmic vesicle);GO:0031629(synaptic vesicle fusion to presynaptic active zone membrane);GO:0031982(vesicle);GO:0035544(negative regulation of SNARE complex assembly);GO:0042734(presynaptic membrane);GO:0042995(cell projection);GO:0043197(dendritic spine);GO:0043679(axon terminus);GO:0045202(synapse);GO:0045211(postsynaptic membrane);GO:0050884(neuromuscular process controlling posture);GO:0098793(presynapse);GO:1905513(negative regulation of short-term synaptic potentiation)","NA","NA","NA","proline rich transmembrane protein 2 [Source:HGNC Symbol;Acc:HGNC:30500]",0,0,0,0,0,0,1,0,1,1,"no","no"]
[52434,0,"chr13","-",75526436,75538802,"ENST00000377612",4,580,"ENSG00000188243","COMMD6","GO:0005515(protein binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0032088(negative regulation of NF-kappaB transcription factor activity);GO:0051059(NF-kappaB binding)","NA","K22562","NA","COMM domain containing 6 [Source:HGNC Symbol;Acc:HGNC:24015]",0,{"v":0.013191,"d":"0.01"},{"v":0.014808,"d":"0.01"},0,{"v":0.030526,"d":"0.03"},0,{"v":0.917218109152853,"d":"0.92"},{"v":-0.124663255748088,"d":"-0.12"},1,1,"down","no"]
[87600,0,"chr17","-",50196079,50196595,"ENST00000485870",2,403,"ENSG00000108821","COL1A1","GO:0001501(skeletal system development);GO:0001503(ossification);GO:0001568(blood vessel development);GO:0001649(osteoblast differentiation);GO:0001957(intramembranous ossification);GO:0001958(endochondral ossification);GO:0002020(protease binding);GO:0005201(extracellular matrix structural constituent);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0005581(collagen trimer);GO:0005584(collagen type I trimer);GO:0005615(extracellular space);GO:0005737(cytoplasm);GO:0005783(endoplasmic reticulum);GO:0005788(endoplasmic reticulum lumen);GO:0005794(Golgi apparatus);GO:0007584(response to nutrient);GO:0007596(blood coagulation);GO:0007601(visual perception);GO:0007605(sensory perception of sound);GO:0009612(response to mechanical stimulus);GO:0010718(positive regulation of epithelial to mesenchymal transition);GO:0010812(negative regulation of cell-substrate adhesion);GO:0015031(protein transport);GO:0030020(extracellular matrix structural constituent conferring tensile strength);GO:0030141(secretory granule);GO:0030168(platelet activation);GO:0030198(extracellular matrix organization);GO:0030199(collagen fibril organization);GO:0030335(positive regulation of cell migration);GO:0031012(extracellular matrix);GO:0031667(response to nutrient levels);GO:0031960(response to corticosteroid);GO:0032355(response to estradiol);GO:0032964(collagen biosynthetic process);GO:0034504(protein localization to nucleus);GO:0034505(tooth mineralization);GO:0038063(collagen-activated tyrosine kinase receptor signaling pathway);GO:0042060(wound healing);GO:0042493(response to drug);GO:0042542(response to hydrogen peroxide);GO:0042802(identical protein binding);GO:0043434(response to peptide hormone);GO:0043588(skin development);GO:0043589(skin morphogenesis);GO:0044344(cellular response to fibroblast growth factor stimulus);GO:0044691(tooth eruption);GO:0045893(positive regulation of transcription, DNA-templated);GO:0046872(metal ion binding);GO:0048407(platelet-derived growth factor binding);GO:0048545(response to steroid hormone);GO:0048705(skeletal system morphogenesis);GO:0048706(embryonic skeletal system development);GO:0050776(regulation of immune response);GO:0050900(leukocyte migration);GO:0051591(response to cAMP);GO:0055093(response to hyperoxia);GO:0060325(face morphogenesis);GO:0060346(bone trabecula formation);GO:0060351(cartilage development involved in endochondral bone morphogenesis);GO:0062023(collagen-containing extracellular matrix);GO:0070208(protein heterotrimerization);GO:0071230(cellular response to amino acid stimulus);GO:0071260(cellular response to mechanical stimulus);GO:0071300(cellular response to retinoic acid);GO:0071306(cellular response to vitamin E);GO:0071356(cellular response to tumor necrosis factor);GO:0071364(cellular response to epidermal growth factor stimulus);GO:0071560(cellular response to transforming growth factor beta stimulus);GO:0090263(positive regulation of canonical Wnt signaling pathway);GO:1902617(response to fluoride);GO:1902618(cellular response to fluoride)","04151(PI3K-Akt signaling pathway);04510(Focal adhesion);04512(ECM-receptor interaction);04611(Platelet activation);04926(Relaxin signaling pathway);04933(AGE-RAGE signaling pathway in diabetic complications);04974(Protein digestion and absorption);05146(Amoebiasis);05165(Human papillomavirus infection)","K06236","NA","collagen type I alpha 1 chain [Source:HGNC Symbol;Acc:HGNC:2197]",{"v":0.175802,"d":"0.18"},{"v":0.182392,"d":"0.18"},{"v":0.289534,"d":"0.29"},{"v":0.237388,"d":"0.24"},{"v":0.416699,"d":"0.42"},{"v":0.270369,"d":"0.27"},{"v":0.70065854946044,"d":"0.70"},{"v":-0.513216545104705,"d":"-0.51"},1,1,"down","no"]
[191396,0,"chr8","-",100008497,100106000,"ENST00000519725",16,2408,"ENSG00000132554","RGS22","GO:0001965(G-protein alpha-subunit binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0009968(negative regulation of signal transduction)","NA","NA","NA","regulator of G protein signaling 22 [Source:HGNC Symbol;Acc:HGNC:24499]",0,{"v":0.008182,"d":"0.01"},0,0,0,0,"inf","inf",1,1,"up","no"]
[21499,0,"chr10","+",68106155,68211699,"ENST00000354393",20,4596,"ENSG00000138347","MYPN","GO:0003779(actin binding);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005886(plasma membrane);GO:0007156(homophilic cell adhesion via plasma membrane adhesion molecules);GO:0007411(axon guidance);GO:0008092(cytoskeletal protein binding);GO:0017124(SH3 domain binding);GO:0030017(sarcomere);GO:0030018(Z disc);GO:0030424(axon);GO:0031674(I band);GO:0045214(sarcomere organization);GO:0051371(muscle alpha-actinin binding);GO:0070593(dendrite self-avoidance);GO:0098632(cell-cell adhesion mediator activity)","NA","K22028","NA","myopalladin [Source:HGNC Symbol;Acc:HGNC:23246]",0,0,0,0,0,0,1,0,1,1,"no","no"]
[104155,0,"chr19","-",40808474,40811097,"ENST00000641596",2,2535,"ENSG00000233622","CYP2T1P","NA","NA","NA","NA","cytochrome P450 family 2 subfamily T member 1, pseudogene [Source:HGNC Symbol;Acc:HGNC:18852]",{"v":0.098681,"d":"0.10"},{"v":0.076151,"d":"0.08"},{"v":0.131816,"d":"0.13"},{"v":0.03849,"d":"0.04"},{"v":0.061247,"d":"0.06"},{"v":0.060978,"d":"0.06"},{"v":1.90802351989547,"d":"1.91"},{"v":0.932078955320057,"d":"0.93"},1,1,"up","no"]
[102224,0,"chr19","+",34365196,34377832,"ENST00000589640",5,571,"ENSG00000105220","GPI","GO:0001701(in utero embryonic development);GO:0001707(mesoderm formation);GO:0004347(glucose-6-phosphate isomerase activity);GO:0005125(cytokine activity);GO:0005576(extracellular region);GO:0005615(extracellular space);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0005975(carbohydrate metabolic process);GO:0006094(gluconeogenesis);GO:0006096(glycolytic process);GO:0006959(humoral immune response);GO:0007599(hemostasis);GO:0007611(learning or memory);GO:0008083(growth factor activity);GO:0010469(regulation of signaling receptor activity);GO:0010595(positive regulation of endothelial cell migration);GO:0016020(membrane);GO:0016853(isomerase activity);GO:0016866(intramolecular transferase activity);GO:0019242(methylglyoxal biosynthetic process);GO:0031625(ubiquitin protein ligase binding);GO:0032355(response to estradiol);GO:0032570(response to progesterone);GO:0033574(response to testosterone);GO:0034101(erythrocyte homeostasis);GO:0034774(secretory granule lumen);GO:0035902(response to immobilization stress);GO:0035994(response to muscle stretch);GO:0042593(glucose homeostasis);GO:0043005(neuron projection);GO:0043154(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process);GO:0043278(response to morphine);GO:0043312(neutrophil degranulation);GO:0043524(negative regulation of neuron apoptotic process);GO:0046185(aldehyde catabolic process);GO:0046686(response to cadmium ion);GO:0048029(monosaccharide binding);GO:0051024(positive regulation of immunoglobulin secretion);GO:0051156(glucose 6-phosphate metabolic process);GO:0060170(ciliary membrane);GO:0061621(canonical glycolysis);GO:0070062(extracellular exosome);GO:1904813(ficolin-1-rich granule lumen)","00010(Glycolysis / Gluconeogenesis);00030(Pentose phosphate pathway);00500(Starch and sucrose metabolism);00520(Amino sugar and nucleotide sugar metabolism)","K01810","EC:5.3.1.9","glucose-6-phosphate isomerase [Source:HGNC Symbol;Acc:HGNC:4458]",0,0,0,{"v":0.289433,"d":"0.29"},0,0,"-inf","-inf",1,1,"down","no"]
[25198,0,"chr10","+",125973499,125995498,"ENST00000445510",5,672,"ENSG00000203780","FANK1","GO:0000785(chromatin);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005856(cytoskeleton);GO:0005929(cilium);GO:0036064(ciliary basal body);GO:0042995(cell projection);GO:0043065(positive regulation of apoptotic process);GO:0043066(negative regulation of apoptotic process);GO:0045893(positive regulation of transcription, DNA-templated);GO:0051091(positive regulation of DNA-binding transcription factor activity)","NA","NA","NA","fibronectin type III and ankyrin repeat domains 1 [Source:HGNC Symbol;Acc:HGNC:23527]",0,0,0,0,0,0,1,0,1,1,"no","no"]
[5846,0,"chr1","-",46557408,46604294,"ENST00000649800",14,2809,"ENSG00000079277","MKNK1","GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0004683(calmodulin-dependent protein kinase activity);GO:0005515(protein binding);GO:0005516(calmodulin binding);GO:0005524(ATP binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0006417(regulation of translation);GO:0006468(protein phosphorylation);GO:0009931(calcium-dependent protein serine/threonine kinase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0016740(transferase activity);GO:0018105(peptidyl-serine phosphorylation);GO:0035556(intracellular signal transduction);GO:0046777(protein autophosphorylation);GO:0046872(metal ion binding)","04010(MAPK signaling pathway);04066(HIF-1 signaling pathway);04910(Insulin signaling pathway)","K04372","EC:2.7.11.1","MAP kinase interacting serine/threonine kinase 1 [Source:HGNC Symbol;Acc:HGNC:7110]",{"v":0.017535,"d":"0.02"},0,{"v":0.006629,"d":"0.01"},{"v":0.014448,"d":"0.01"},{"v":0.012645,"d":"0.01"},{"v":0.012253,"d":"0.01"},{"v":0.61414120876328,"d":"0.61"},{"v":-0.703357683982408,"d":"-0.70"},1,1,"down","no"]
[51692,0,"chr13","-",48340797,48341330,"ENST00000613946",1,534,"ENSG00000277684","AL392048","NA","NA","NA","NA","novel transcript, antisense to RB1",0,0,0,0,0,{"v":0.08127,"d":"0.08"},"-inf","-inf",1,1,"down","no"]
[136678,0,"chr3","+",9917098,9933617,"ENST00000498214",16,2357,"ENSG00000163702","IL17RC","GO:0005102(signaling receptor binding);GO:0005886(plasma membrane);GO:0009986(cell surface);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0019221(cytokine-mediated signaling pathway);GO:0030368(interleukin-17 receptor activity);GO:0050832(defense response to fungus);GO:0071621(granulocyte chemotaxis);GO:0097400(interleukin-17-mediated signaling pathway);GO:1900017(positive regulation of cytokine production involved in inflammatory response);GO:2000778(positive regulation of interleukin-6 secretion)","04060(Cytokine-cytokine receptor interaction);04657(IL-17 signaling pathway)","K05166","NA","interleukin 17 receptor C [Source:HGNC Symbol;Acc:HGNC:18358]",{"v":0.171869,"d":"0.17"},{"v":0.236151,"d":"0.24"},{"v":0.115083,"d":"0.12"},{"v":0.400895,"d":"0.40"},0,{"v":0.229356,"d":"0.23"},{"v":0.829991543051895,"d":"0.83"},{"v":-0.268831458258221,"d":"-0.27"},1,1,"down","no"]
[175008,0,"chr6","+",151593028,151615520,"ENST00000537358",3,574,"ENSG00000120262","CCDC170","GO:0005515(protein binding)","NA","NA","NA","coiled-coil domain containing 170 [Source:HGNC Symbol;Acc:HGNC:21177]",{"v":0.015286,"d":"0.02"},{"v":0.003482,"d":"0.00"},{"v":0.120821,"d":"0.12"},{"v":0.059203,"d":"0.06"},{"v":0.113335,"d":"0.11"},{"v":0.307557,"d":"0.31"},{"v":0.290752871827451,"d":"0.29"},{"v":-1.78213465331523,"d":"-1.78"},1,1,"down","no"]
[79691,0,"chr17","-",1783110,1783863,"ENST00000476292",2,553,"ENSG00000186532","SMYD4","GO:0005515(protein binding);GO:0008168(methyltransferase activity);GO:0016740(transferase activity);GO:0032259(methylation);GO:0046872(metal ion binding)","NA","NA","NA","SET and MYND domain containing 4 [Source:HGNC Symbol;Acc:HGNC:21067]",{"v":0.405503,"d":"0.41"},{"v":0.564162,"d":"0.56"},{"v":0.547597,"d":"0.55"},{"v":0.31525,"d":"0.32"},{"v":0.160197,"d":"0.16"},{"v":0.120457,"d":"0.12"},{"v":2.54615172913758,"d":"2.55"},{"v":1.34831839424004,"d":"1.35"},1,1,"up","no"]
[198242,0,"chr9","-",109171975,109320964,"ENST00000374566",26,5800,"ENSG00000095203","EPB41L4B","GO:0005200(structural constituent of cytoskeleton);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005856(cytoskeleton);GO:0005886(plasma membrane);GO:0005923(bicellular tight junction);GO:0008092(cytoskeletal protein binding);GO:0010628(positive regulation of gene expression);GO:0030054(cell junction);GO:0031032(actomyosin structure organization);GO:0042060(wound healing);GO:0045177(apical part of cell);GO:0045785(positive regulation of cell adhesion);GO:0051549(positive regulation of keratinocyte migration)","04530(Tight junction)","K21111","NA","erythrocyte membrane protein band 4.1 like 4B [Source:HGNC Symbol;Acc:HGNC:19818]",0,0,{"v":0.017981,"d":"0.02"},{"v":0.043351,"d":"0.04"},{"v":0.009083,"d":"0.01"},{"v":0.012835,"d":"0.01"},{"v":0.275490661723023,"d":"0.28"},{"v":-1.8599246781389,"d":"-1.86"},1,1,"down","no"]
[168708,0,"chr6","-",30705448,30711914,"ENST00000417033",5,916,"ENSG00000137337","MDC1","GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005694(chromosome);GO:0005925(focal adhesion);GO:0006281(DNA repair);GO:0006303(double-strand break repair via nonhomologous end joining);GO:0006974(cellular response to DNA damage stimulus);GO:0007049(cell cycle);GO:0008022(protein C-terminus binding);GO:0016604(nuclear body);GO:0031573(intra-S DNA damage checkpoint);GO:0042802(identical protein binding);GO:0070975(FHA domain binding)","NA","K20780","NA","mediator of DNA damage checkpoint 1 [Source:HGNC Symbol;Acc:HGNC:21163]",{"v":0.718982,"d":"0.72"},{"v":0.751479,"d":"0.75"},{"v":0.8578,"d":"0.86"},{"v":0.195099,"d":"0.20"},{"v":0.343209,"d":"0.34"},0,{"v":4.32514657036492,"d":"4.33"},{"v":2.11274902355992,"d":"2.11"},1,1,"up","no"]
[111285,0,"chr2","-",33591923,33599382,"ENST00000464415",3,655,"ENSG00000119812","FAM98A","GO:0003723(RNA binding);GO:0005515(protein binding);GO:0006479(protein methylation);GO:0008276(protein methyltransferase activity);GO:0008284(positive regulation of cell population proliferation);GO:0010628(positive regulation of gene expression);GO:0032418(lysosome localization);GO:0072669(tRNA-splicing ligase complex);GO:1900029(positive regulation of ruffle assembly)","NA","NA","NA","family with sequence similarity 98 member A [Source:HGNC Symbol;Acc:HGNC:24520]",{"v":0.820394,"d":"0.82"},{"v":0.998883,"d":"1.00"},{"v":0.404794,"d":"0.40"},{"v":0.656498,"d":"0.66"},{"v":0.005416,"d":"0.01"},{"v":0.912102,"d":"0.91"},{"v":1.41299135459868,"d":"1.41"},{"v":0.498752638555247,"d":"0.50"},1,1,"up","no"]
[193875,0,"chr8","-",144423621,144426983,"ENST00000530983",5,2337,"ENSG00000160948","VPS28","GO:0000813(ESCRT I complex);GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0005768(endosome);GO:0005769(early endosome);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0010008(endosome membrane);GO:0015031(protein transport);GO:0016020(membrane);GO:0016197(endosomal transport);GO:0016236(macroautophagy);GO:0019058(viral life cycle);GO:0031397(negative regulation of protein ubiquitination);GO:0031902(late endosome membrane);GO:0032509(endosome transport via multivesicular body sorting pathway);GO:0036258(multivesicular body assembly);GO:0039702(viral budding via host ESCRT complex);GO:0043130(ubiquitin binding);GO:0043162(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway);GO:0043328(protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway);GO:0043657(host cell);GO:0044877(protein-containing complex binding);GO:0045732(positive regulation of protein catabolic process);GO:0070062(extracellular exosome);GO:0075733(intracellular transport of virus);GO:2000397(positive regulation of ubiquitin-dependent endocytosis)","04144(Endocytosis)","K12184","NA","VPS28, ESCRT-I subunit [Source:HGNC Symbol;Acc:HGNC:18178]",{"v":0.119679,"d":"0.12"},{"v":0.238837,"d":"0.24"},{"v":0.353477,"d":"0.35"},{"v":0.284886,"d":"0.28"},{"v":0.256403,"d":"0.26"},{"v":0.08214,"d":"0.08"},{"v":1.14205948071071,"d":"1.14"},{"v":0.191637791061259,"d":"0.19"},1,1,"up","no"]
[109683,0,"chr2","+",7421261,7445890,"ENST00000441014",5,469,"ENSG00000229727","AC013460","NA","NA","NA","NA","novel transcript",0,0,0,0,0,0,1,0,1,1,"no","no"]
[43435,0,"chr12","-",53307460,53324758,"ENST00000550286",15,1652,"ENSG00000094914","AAAS","GO:0003674(molecular_function);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005635(nuclear envelope);GO:0005643(nuclear pore);GO:0005654(nucleoplasm);GO:0005813(centrosome);GO:0005829(cytosol);GO:0006110(regulation of glycolytic process);GO:0006406(mRNA export from nucleus);GO:0006409(tRNA export from nucleus);GO:0006913(nucleocytoplasmic transport);GO:0007612(learning);GO:0009566(fertilization);GO:0015031(protein transport);GO:0016020(membrane);GO:0016032(viral process);GO:0016925(protein sumoylation);GO:0019083(viral transcription);GO:0031965(nuclear membrane);GO:0043657(host cell);GO:0046822(regulation of nucleocytoplasmic transport);GO:0051028(mRNA transport);GO:0060964(regulation of gene silencing by miRNA);GO:0075733(intracellular transport of virus);GO:1900034(regulation of cellular response to heat)","03013(RNA transport)","K14320","NA","aladin WD repeat nucleoporin [Source:HGNC Symbol;Acc:HGNC:13666]",0,0,0,0,0,{"v":0.025533,"d":"0.03"},"-inf","-inf",1,1,"down","no"]
[141937,0,"chr3","+",77629122,77649500,"ENST00000470802",3,9570,"ENSG00000185008","ROBO2","GO:0001656(metanephros development);GO:0001657(ureteric bud development);GO:0001822(kidney development);GO:0003148(outflow tract septum morphogenesis);GO:0003180(aortic valve morphogenesis);GO:0003184(pulmonary valve morphogenesis);GO:0003272(endocardial cushion formation);GO:0005515(protein binding);GO:0005886(plasma membrane);GO:0006935(chemotaxis);GO:0007155(cell adhesion);GO:0007156(homophilic cell adhesion via plasma membrane adhesion molecules);GO:0007275(multicellular organism development);GO:0007399(nervous system development);GO:0007411(axon guidance);GO:0007417(central nervous system development);GO:0007420(brain development);GO:0008046(axon guidance receptor activity);GO:0009986(cell surface);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016199(axon midline choice point recognition);GO:0021510(spinal cord development);GO:0021891(olfactory bulb interneuron development);GO:0030154(cell differentiation);GO:0030673(axolemma);GO:0031290(retinal ganglion cell axon guidance);GO:0032870(cellular response to hormone stimulus);GO:0035385(Roundabout signaling pathway);GO:0035481(positive regulation of Notch signaling pathway involved in heart induction);GO:0035904(aorta development);GO:0042802(identical protein binding);GO:0050772(positive regulation of axonogenesis);GO:0050925(negative regulation of negative chemotaxis);GO:0051964(negative regulation of synapse assembly);GO:0060412(ventricular septum morphogenesis);GO:0061364(apoptotic process involved in luteolysis);GO:0070062(extracellular exosome)","04360(Axon guidance)","K06754","NA","roundabout guidance receptor 2 [Source:HGNC Symbol;Acc:HGNC:10250]",{"v":0.010254,"d":"0.01"},{"v":0.002267,"d":"0.00"},0,{"v":0.092308,"d":"0.09"},0,{"v":0.080085,"d":"0.08"},{"v":0.072630559245445,"d":"0.07"},{"v":-3.78327950111801,"d":"-3.78"},1,1,"down","no"]
[179473,0,"chr7","+",64551498,64552066,"ENST00000454982",1,569,"ENSG00000223974","BNIP3P42","NA","NA","NA","NA","BCL2 interacting protein 3 pseudogene 42 [Source:HGNC Symbol;Acc:HGNC:49722]",0,0,0,0,0,0,1,0,1,1,"no","no"]
[190194,0,"chr8","+",73976207,73981366,"ENST00000517439",3,617,"ENSG00000175606","TMEM70","GO:0003674(molecular_function);GO:0005654(nucleoplasm);GO:0005739(mitochondrion);GO:0005743(mitochondrial inner membrane);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0032592(integral component of mitochondrial membrane);GO:0033615(mitochondrial proton-transporting ATP synthase complex assembly)","NA","K17966","NA","transmembrane protein 70 [Source:HGNC Symbol;Acc:HGNC:26050]",{"v":0.014048,"d":"0.01"},{"v":0.105921,"d":"0.11"},0,0,{"v":0.649027,"d":"0.65"},0,{"v":0.184844390140934,"d":"0.18"},{"v":-2.43561683517971,"d":"-2.44"},1,1,"down","no"]
[199103,0,"chr9","-",125559783,125657710,"ENST00000468896",4,401,"ENSG00000119487","MAPKAP1","GO:0005515(protein binding);GO:0005546(phosphatidylinositol-4,5-bisphosphate binding);GO:0005547(phosphatidylinositol-3,4,5-trisphosphate binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0005794(Golgi apparatus);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0016020(membrane);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0017016(Ras GTPase binding);GO:0019901(protein kinase binding);GO:0021762(substantia nigra development);GO:0030950(establishment or maintenance of actin cytoskeleton polarity);GO:0031410(cytoplasmic vesicle);GO:0031932(TORC2 complex);GO:0032148(activation of protein kinase B activity);GO:0033138(positive regulation of peptidyl-serine phosphorylation);GO:0038203(TORC2 signaling);GO:0043325(phosphatidylinositol-3,4-bisphosphate binding);GO:0046580(negative regulation of Ras protein signal transduction);GO:0070300(phosphatidic acid binding);GO:0080025(phosphatidylinositol-3,5-bisphosphate binding);GO:1900407(regulation of cellular response to oxidative stress)","04150(mTOR signaling pathway)","K20410","NA","mitogen-activated protein kinase associated protein 1 [Source:HGNC Symbol;Acc:HGNC:18752]",{"v":0.125572,"d":"0.13"},{"v":0.060334,"d":"0.06"},0,0,0,0,"inf","inf",1,1,"up","no"]
[154693,0,"chr4","+",127880899,127883470,"ENST00000503914",3,571,"ENSG00000142731","PLK4","GO:0000086(G2/M transition of mitotic cell cycle);GO:0000166(nucleotide binding);GO:0001741(XY body);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005515(protein binding);GO:0005524(ATP binding);GO:0005634(nucleus);GO:0005730(nucleolus);GO:0005737(cytoplasm);GO:0005813(centrosome);GO:0005814(centriole);GO:0005829(cytosol);GO:0005856(cytoskeleton);GO:0006468(protein phosphorylation);GO:0007099(centriole replication);GO:0010389(regulation of G2/M transition of mitotic cell cycle);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0016740(transferase activity);GO:0032154(cleavage furrow);GO:0042802(identical protein binding);GO:0046601(positive regulation of centriole replication);GO:0060707(trophoblast giant cell differentiation);GO:0097711(ciliary basal body-plasma membrane docking);GO:0098535(de novo centriole assembly involved in multi-ciliated epithelial cell differentiation);GO:0098536(deuterosome)","04068(FoxO signaling pathway)","K08863","EC:2.7.11.21","polo like kinase 4 [Source:HGNC Symbol;Acc:HGNC:11397]",{"v":0.093978,"d":"0.09"},0,0,0,0,0,"inf","inf",1,1,"up","no"]
[144159,0,"chr3","+",129487506,129520355,"ENST00000511425",15,2225,"ENSG00000163913","IFT122","GO:0001843(neural tube closure);GO:0005515(protein binding);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005856(cytoskeleton);GO:0005929(cilium);GO:0007227(signal transduction downstream of smoothened);GO:0007275(multicellular organism development);GO:0009953(dorsal/ventral pattern formation);GO:0010172(embryonic body morphogenesis);GO:0016020(membrane);GO:0021914(negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning);GO:0030030(cell projection organization);GO:0030991(intraciliary transport particle A);GO:0032391(photoreceptor connecting cilium);GO:0035050(embryonic heart tube development);GO:0035115(embryonic forelimb morphogenesis);GO:0035720(intraciliary anterograde transport);GO:0035721(intraciliary retrograde transport);GO:0035735(intraciliary transport involved in cilium assembly);GO:0036064(ciliary basal body);GO:0042733(embryonic digit morphogenesis);GO:0042995(cell projection);GO:0045879(negative regulation of smoothened signaling pathway);GO:0048593(camera-type eye morphogenesis);GO:0050680(negative regulation of epithelial cell proliferation);GO:0060173(limb development);GO:0060271(cilium assembly);GO:0060830(ciliary receptor clustering involved in smoothened signaling pathway);GO:0060831(smoothened signaling pathway involved in dorsal/ventral neural tube patterning);GO:0060971(embryonic heart tube left/right pattern formation);GO:0061512(protein localization to cilium);GO:0072594(establishment of protein localization to organelle);GO:0097542(ciliary tip);GO:0097546(ciliary base);GO:1905515(non-motile cilium assembly)","NA","K19656","NA","intraflagellar transport 122 [Source:HGNC Symbol;Acc:HGNC:13556]",0,{"v":0.019568,"d":"0.02"},0,0,0,0,"inf","inf",1,1,"up","no"]
[79293,0,"chr16","+",90019730,90031499,"ENST00000568664",4,341,"ENSG00000141013","GAS8","GO:0003351(epithelial cilium movement);GO:0003674(molecular_function);GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0005794(Golgi apparatus);GO:0005856(cytoskeleton);GO:0005874(microtubule);GO:0005929(cilium);GO:0005930(axoneme);GO:0007368(determination of left/right symmetry);GO:0007420(brain development);GO:0008017(microtubule binding);GO:0008285(negative regulation of cell population proliferation);GO:0015630(microtubule cytoskeleton);GO:0017137(Rab GTPase binding);GO:0030317(flagellated sperm motility);GO:0031514(motile cilium);GO:0034613(cellular protein localization);GO:0035082(axoneme assembly);GO:0036064(ciliary basal body);GO:0036126(sperm flagellum);GO:0042995(cell projection);GO:0045880(positive regulation of smoothened signaling pathway);GO:0048870(cell motility);GO:0060294(cilium movement involved in cell motility);GO:0097729(9+2 motile cilium);GO:1903566(positive regulation of protein localization to cilium);GO:1904526(regulation of microtubule binding)","NA","NA","NA","growth arrest specific 8 [Source:HGNC Symbol;Acc:HGNC:4166]",0,0,0,0,0,0,1,0,1,1,"no","no"]
[112066,0,"chr2","+",46845876,46859006,"ENST00000468141",3,2157,"ENSG00000239332","LINC01119","NA","NA","NA","NA","long intergenic non-protein coding RNA 1119 [Source:HGNC Symbol;Acc:HGNC:49262]",{"v":6.9e-5,"d":"0.00"},{"v":0.244323,"d":"0.24"},{"v":8.2e-5,"d":"0.00"},{"v":0.021693,"d":"0.02"},{"v":8.5e-5,"d":"0.00"},{"v":0.185015,"d":"0.19"},{"v":1.18221603245758,"d":"1.18"},{"v":0.241493690741371,"d":"0.24"},1,1,"up","no"]
[1016,0,"chr1","+",6026300,6095625,"ENST00000428161",12,961,"ENSG00000069424","KCNAB2","GO:0002244(hematopoietic progenitor cell differentiation);GO:0004033(aldo-keto reductase (NADP) activity);GO:0005244(voltage-gated ion channel activity);GO:0005249(voltage-gated potassium channel activity);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005856(cytoskeleton);GO:0005874(microtubule);GO:0005886(plasma membrane);GO:0006811(ion transport);GO:0006813(potassium ion transport);GO:0008076(voltage-gated potassium channel complex);GO:0014069(postsynaptic density);GO:0015459(potassium channel regulator activity);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016491(oxidoreductase activity);GO:0030054(cell junction);GO:0030424(axon);GO:0031234(extrinsic component of cytoplasmic side of plasma membrane);GO:0034220(ion transmembrane transport);GO:0034765(regulation of ion transmembrane transport);GO:0035579(specific granule membrane);GO:0042995(cell projection);GO:0043005(neuron projection);GO:0043312(neutrophil degranulation);GO:0043679(axon terminus);GO:0044224(juxtaparanode region of axon);GO:0045202(synapse);GO:0050905(neuromuscular process);GO:0055085(transmembrane transport);GO:0055114(oxidation-reduction process);GO:0070821(tertiary granule membrane);GO:0070995(NADPH oxidation);GO:0071805(potassium ion transmembrane transport);GO:1901379(regulation of potassium ion transmembrane transport);GO:1990031(pinceau fiber);GO:2000008(regulation of protein localization to cell surface)","NA","K04883","NA","potassium voltage-gated channel subfamily A regulatory beta subunit 2 [Source:HGNC Symbol;Acc:HGNC:6229]",0,0,0,0,0,0,1,0,1,1,"no","no"]
[6682,0,"chr1","-",56998025,57291066,"ENST00000420954",14,1817,"ENSG00000173406","DAB1","GO:0001764(neuron migration);GO:0005515(protein binding);GO:0005829(cytosol);GO:0005903(brush border);GO:0007162(negative regulation of cell adhesion);GO:0007264(small GTPase mediated signal transduction);GO:0007275(multicellular organism development);GO:0007399(nervous system development);GO:0007411(axon guidance);GO:0007420(brain development);GO:0007494(midgut development);GO:0007628(adult walking behavior);GO:0014069(postsynaptic density);GO:0016020(membrane);GO:0016358(dendrite development);GO:0021517(ventral spinal cord development);GO:0021589(cerebellum structural organization);GO:0021766(hippocampus development);GO:0021795(cerebral cortex cell migration);GO:0021799(cerebral cortex radially oriented cell migration);GO:0021813(cell-cell adhesion involved in neuronal-glial interactions involved in cerebral cortex radial glia guided migration);GO:0021942(radial glia guided migration of Purkinje cell);GO:0021987(cerebral cortex development);GO:0030154(cell differentiation);GO:0042493(response to drug);GO:0043005(neuron projection);GO:0043025(neuronal cell body);GO:0043231(intracellular membrane-bounded organelle);GO:0043548(phosphatidylinositol 3-kinase binding);GO:0045177(apical part of cell);GO:0045666(positive regulation of neuron differentiation);GO:0045860(positive regulation of protein kinase activity);GO:0046426(negative regulation of receptor signaling pathway via JAK-STAT);GO:0048471(perinuclear region of cytoplasm);GO:0048712(negative regulation of astrocyte differentiation);GO:0050771(negative regulation of axonogenesis);GO:0051645(Golgi localization);GO:0097477(lateral motor column neuron migration)","NA","K20054","NA","DAB1, reelin adaptor protein [Source:HGNC Symbol;Acc:HGNC:2661]",0,{"v":0.306154,"d":"0.31"},{"v":0.296901,"d":"0.30"},{"v":0.501849,"d":"0.50"},0,{"v":0.026032,"d":"0.03"},{"v":1.14240709553858,"d":"1.14"},{"v":0.192076845147129,"d":"0.19"},1,1,"up","no"]
[134061,0,"chr22","+",35299856,35347973,"ENST00000404284",17,2622,"ENSG00000100284","TOM1","GO:0005515(protein binding);GO:0005622(intracellular);GO:0005623(cell);GO:0005737(cytoplasm);GO:0005768(endosome);GO:0005769(early endosome);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0006886(intracellular protein transport);GO:0006897(endocytosis);GO:0015031(protein transport);GO:0016020(membrane);GO:0016197(endosomal transport);GO:0030276(clathrin binding);GO:0035577(azurophil granule membrane);GO:0035579(specific granule membrane);GO:0043312(neutrophil degranulation);GO:0070062(extracellular exosome)","NA","NA","NA","target of myb1 membrane trafficking protein [Source:HGNC Symbol;Acc:HGNC:11982]",{"v":0.118014,"d":"0.12"},{"v":0.07092,"d":"0.07"},{"v":0.171074,"d":"0.17"},{"v":0.139903,"d":"0.14"},{"v":0.132461,"d":"0.13"},{"v":0.112211,"d":"0.11"},{"v":0.936119092504713,"d":"0.94"},{"v":-0.0952360146123943,"d":"-0.10"},1,1,"down","no"]
[156636,0,"chr4","+",183444697,183446021,"ENST00000510928",2,860,"ENSG00000168564","CDKN2AIP","GO:0001652(granular component);GO:0002039(p53 binding);GO:0003723(RNA binding);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005730(nucleolus);GO:0006974(cellular response to DNA damage stimulus);GO:0009967(positive regulation of signal transduction);GO:0030307(positive regulation of cell growth);GO:0030308(negative regulation of cell growth);GO:0031647(regulation of protein stability)","NA","NA","NA","CDKN2A interacting protein [Source:HGNC Symbol;Acc:HGNC:24325]",{"v":0.389483,"d":"0.39"},{"v":0.108012,"d":"0.11"},{"v":0.382944,"d":"0.38"},{"v":0.415595,"d":"0.42"},{"v":0.186676,"d":"0.19"},{"v":0.107622,"d":"0.11"},{"v":1.2402418392631,"d":"1.24"},{"v":0.310621464391736,"d":"0.31"},1,1,"up","no"]
[137310,0,"chr3","-",15596152,15601569,"ENST00000460907",3,565,"ENSG00000131373","HACL1","GO:0000287(magnesium ion binding);GO:0001561(fatty acid alpha-oxidation);GO:0003824(catalytic activity);GO:0005102(signaling receptor binding);GO:0005515(protein binding);GO:0005777(peroxisome);GO:0005782(peroxisomal matrix);GO:0005829(cytosol);GO:0006625(protein targeting to peroxisome);GO:0006629(lipid metabolic process);GO:0006631(fatty acid metabolic process);GO:0016829(lyase activity);GO:0016830(carbon-carbon lyase activity);GO:0030976(thiamine pyrophosphate binding);GO:0042802(identical protein binding);GO:0046872(metal ion binding);GO:0048037(cofactor binding);GO:0051259(protein complex oligomerization)","04146(Peroxisome)","K12261","EC:4.1.-.-","2-hydroxyacyl-CoA lyase 1 [Source:HGNC Symbol;Acc:HGNC:17856]",{"v":0.000461,"d":"0.00"},{"v":0.114717,"d":"0.11"},{"v":0.238737,"d":"0.24"},{"v":0.007497,"d":"0.01"},{"v":0.017565,"d":"0.02"},{"v":0.013438,"d":"0.01"},{"v":9.1925974025974,"d":"9.19"},{"v":3.20047255796648,"d":"3.20"},1,1,"up","no"]
[201579,0,"chrX","-",13715537,13734545,"ENST00000519382",4,1411,"ENSG00000196459","TRAPPC2","GO:0000139(Golgi membrane);GO:0001501(skeletal system development);GO:0005515(protein binding);GO:0005622(intracellular);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0005783(endoplasmic reticulum);GO:0005793(endoplasmic reticulum-Golgi intermediate compartment);GO:0005829(cytosol);GO:0006355(regulation of transcription, DNA-templated);GO:0006888(endoplasmic reticulum to Golgi vesicle-mediated transport);GO:0008134(transcription factor binding);GO:0016192(vesicle-mediated transport);GO:0030008(TRAPP complex);GO:0043231(intracellular membrane-bounded organelle);GO:0044325(ion channel binding);GO:0048208(COPII vesicle coating);GO:0048471(perinuclear region of cytoplasm)","NA","K20301","NA","trafficking protein particle complex 2 [Source:HGNC Symbol;Acc:HGNC:23068]",{"v":0.34333,"d":"0.34"},0,{"v":0.595018,"d":"0.60"},{"v":0.574447,"d":"0.57"},{"v":0.222911,"d":"0.22"},{"v":0.258085,"d":"0.26"},{"v":0.889056064609837,"d":"0.89"},{"v":-0.169653695422624,"d":"-0.17"},1,1,"down","no"]
[137019,0,"chr3","-",12587577,12592068,"ENST00000475353",3,599,"ENSG00000132155","RAF1","GO:0000165(MAPK cascade);GO:0000166(nucleotide binding);GO:0000186(activation of MAPKK activity);GO:0001666(response to hypoxia);GO:0001678(cellular glucose homeostasis);GO:0001934(positive regulation of protein phosphorylation);GO:0002223(stimulatory C-type lectin receptor signaling pathway);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0004709(MAP kinase kinase kinase activity);GO:0005515(protein binding);GO:0005524(ATP binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005739(mitochondrion);GO:0005741(mitochondrial outer membrane);GO:0005794(Golgi apparatus);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0006468(protein phosphorylation);GO:0006915(apoptotic process);GO:0007165(signal transduction);GO:0007190(activation of adenylate cyclase activity);GO:0007507(heart development);GO:0008179(adenylate cyclase binding);GO:0008283(cell population proliferation);GO:0008285(negative regulation of cell population proliferation);GO:0010856(adenylate cyclase activator activity);GO:0016020(membrane);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0016607(nuclear speck);GO:0016740(transferase activity);GO:0017016(Ras GTPase binding);GO:0019899(enzyme binding);GO:0030154(cell differentiation);GO:0030168(platelet activation);GO:0030878(thyroid gland development);GO:0031143(pseudopodium);GO:0031333(negative regulation of protein complex assembly);GO:0031434(mitogen-activated protein kinase kinase binding);GO:0033138(positive regulation of peptidyl-serine phosphorylation);GO:0034220(ion transmembrane transport);GO:0035019(somatic stem cell population maintenance);GO:0035023(regulation of Rho protein signal transduction);GO:0035556(intracellular signal transduction);GO:0035773(insulin secretion involved in cellular response to glucose stimulus);GO:0035994(response to muscle stretch);GO:0042060(wound healing);GO:0042802(identical protein binding);GO:0042981(regulation of apoptotic process);GO:0043066(negative regulation of apoptotic process);GO:0043085(positive regulation of catalytic activity);GO:0043154(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process);GO:0045104(intermediate filament cytoskeleton organization);GO:0045595(regulation of cell differentiation);GO:0045944(positive regulation of transcription by RNA polymerase II);GO:0046872(metal ion binding);GO:0046982(protein heterodimerization activity);GO:0048011(neurotrophin TRK receptor signaling pathway);GO:0048538(thymus development);GO:0060324(face development);GO:0071550(death-inducing signaling complex assembly);GO:1902042(negative regulation of extrinsic apoptotic signaling pathway via death domain receptors);GO:2000145(regulation of cell motility)","01521(EGFR tyrosine kinase inhibitor resistance);01522(Endocrine resistance);04010(MAPK signaling pathway);04012(ErbB signaling pathway);04014(Ras signaling pathway);04015(Rap1 signaling pathway);04022(cGMP-PKG signaling pathway);04024(cAMP signaling pathway);04062(Chemokine signaling pathway);04068(FoxO signaling pathway);04071(Sphingolipid signaling pathway);04072(Phospholipase D signaling pathway);04140(Autophagy - animal);04150(mTOR signaling pathway);04151(PI3K-Akt signaling pathway);04210(Apoptosis);04218(Cellular senescence);04270(Vascular smooth muscle contraction);04360(Axon guidance);04370(VEGF signaling pathway);04371(Apelin signaling pathway);04510(Focal adhesion);04540(Gap junction);04550(Signaling pathways regulating pluripotency of stem cells);04625(C-type lectin receptor signaling pathway);04630(Jak-STAT signaling pathway);04650(Natural killer cell mediated cytotoxicity);04660(T cell receptor signaling pathway);04662(B cell receptor signaling pathway);04664(Fc epsilon RI signaling pathway);04666(Fc gamma R-mediated phagocytosis);04720(Long-term potentiation);04722(Neurotrophin signaling pathway);04726(Serotonergic synapse);04730(Long-term depression);04810(Regulation of actin cytoskeleton);04910(Insulin signaling pathway);04912(GnRH signaling pathway);04914(Progesterone-mediated oocyte maturation);04915(Estrogen signaling pathway);04916(Melanogenesis);04917(Prolactin signaling pathway);04919(Thyroid hormone signaling pathway);04921(Oxytocin signaling pathway);04926(Relaxin signaling pathway);04928(Parathyroid hormone synthesis, secretion and action);05034(Alcoholism);05152(Tuberculosis);05160(Hepatitis C);05161(Hepatitis B);05163(Human cytomegalovirus infection);05164(Influenza A);05165(Human papillomavirus infection);05167(Kaposi sarcoma-associated herpesvirus infection);05170(Human immunodeficiency virus 1 infection);05200(Pathways in cancer);05205(Proteoglycans in cancer);05206(MicroRNAs in cancer);05210(Colorectal cancer);05211(Renal cell carcinoma);05212(Pancreatic cancer);05213(Endometrial cancer);05214(Glioma);05215(Prostate cancer);05218(Melanoma);05219(Bladder cancer);05220(Chronic myeloid leukemia);05221(Acute myeloid leukemia);05223(Non-small cell lung cancer);05224(Breast cancer);05225(Hepatocellular carcinoma);05226(Gastric cancer);05230(Central carbon metabolism in cancer);05231(Choline metabolism in cancer)","K04366","EC:2.7.11.1","Raf-1 proto-oncogene, serine/threonine kinase [Source:HGNC Symbol;Acc:HGNC:9829]",{"v":0.080963,"d":"0.08"},{"v":0.007763,"d":"0.01"},{"v":0.107829,"d":"0.11"},{"v":0.100193,"d":"0.10"},{"v":0.120427,"d":"0.12"},{"v":0.194549,"d":"0.19"},{"v":0.473433710127683,"d":"0.47"},{"v":-1.07876566025007,"d":"-1.08"},1,1,"down","no"]
[199063,0,"chr9","+",125261810,125302148,"ENST00000461379",4,582,"ENSG00000165219","GAPVD1","GO:0005085(guanyl-nucleotide exchange factor activity);GO:0005096(GTPase activator activity);GO:0005768(endosome);GO:0005829(cytosol);GO:0006897(endocytosis);GO:0007165(signal transduction);GO:0016020(membrane);GO:0032794(GTPase activating protein binding);GO:0043087(regulation of GTPase activity);GO:0043547(positive regulation of GTPase activity);GO:0045296(cadherin binding);GO:0051223(regulation of protein transport);GO:0061024(membrane organization)","NA","NA","NA","GTPase activating protein and VPS9 domains 1 [Source:HGNC Symbol;Acc:HGNC:23375]",{"v":0.491484,"d":"0.49"},{"v":1.301297,"d":"1.30"},0,{"v":0.165626,"d":"0.17"},{"v":0.356696,"d":"0.36"},{"v":0.689747,"d":"0.69"},{"v":1.47910803757872,"d":"1.48"},{"v":0.56472743417229,"d":"0.56"},1,1,"up","no"]
[69017,0,"chr15","+",101961604,101973225,"ENST00000558686",5,561,"ENSG00000185596","WASH3P","NA","NA","NA","NA","WAS protein family homolog 3, pseudogene [Source:HGNC Symbol;Acc:HGNC:24362]",{"v":0.30575,"d":"0.31"},{"v":0.035595,"d":"0.04"},0,{"v":0.000404,"d":"0.00"},{"v":0.000129,"d":"0.00"},{"v":0.316118,"d":"0.32"},{"v":1.07798491083243,"d":"1.08"},{"v":0.108336984009176,"d":"0.11"},1,1,"up","no"]
[113727,0,"chr2","+",71570138,71570916,"ENST00000461565",2,515,"ENSG00000135636","DYSF","GO:0001525(angiogenesis);GO:0001778(plasma membrane repair);GO:0001938(positive regulation of endothelial cell proliferation);GO:0002280(monocyte activation involved in immune response);GO:0002281(macrophage activation involved in immune response);GO:0005509(calcium ion binding);GO:0005515(protein binding);GO:0005543(phospholipid binding);GO:0005544(calcium-dependent phospholipid binding);GO:0005634(nucleus);GO:0005768(endosome);GO:0005769(early endosome);GO:0005770(late endosome);GO:0005794(Golgi apparatus);GO:0005815(microtubule organizing center);GO:0005874(microtubule);GO:0005886(plasma membrane);GO:0006071(glycerol metabolic process);GO:0006906(vesicle fusion);GO:0006936(muscle contraction);GO:0008017(microtubule binding);GO:0008289(lipid binding);GO:0010629(negative regulation of gene expression);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0019915(lipid storage);GO:0030027(lamellipodium);GO:0030139(endocytic vesicle);GO:0030315(T-tubule);GO:0030659(cytoplasmic vesicle membrane);GO:0031410(cytoplasmic vesicle);GO:0033292(T-tubule organization);GO:0042177(negative regulation of protein catabolic process);GO:0042383(sarcolemma);GO:0043014(alpha-tubulin binding);GO:0043403(skeletal muscle tissue regeneration);GO:0045444(fat cell differentiation);GO:0045785(positive regulation of cell adhesion);GO:0046872(metal ion binding);GO:0048747(muscle fiber development);GO:0050663(cytokine secretion);GO:0050765(negative regulation of phagocytosis);GO:0070062(extracellular exosome);GO:0071470(cellular response to osmotic stress);GO:0090023(positive regulation of neutrophil chemotaxis);GO:0090279(regulation of calcium ion import);GO:0098857(membrane microdomain);GO:1901842(negative regulation of high voltage-gated calcium channel activity);GO:1902915(negative regulation of protein polyubiquitination)","NA","K18261","NA","dysferlin [Source:HGNC Symbol;Acc:HGNC:3097]",{"v":0.122303,"d":"0.12"},0,{"v":0.054653,"d":"0.05"},0,{"v":0.050366,"d":"0.05"},{"v":0.027075,"d":"0.03"},{"v":2.28504280678194,"d":"2.29"},{"v":1.19222119222144,"d":"1.19"},1,1,"up","no"]
[89748,0,"chr17","-",72427334,72592692,"ENST00000649343",3,1552,"ENSG00000227036","LINC00511","NA","NA","NA","NA","long intergenic non-protein coding RNA 511 [Source:HGNC Symbol;Acc:HGNC:43564]",{"v":0.174442,"d":"0.17"},{"v":0.003146,"d":"0.00"},{"v":0.016064,"d":"0.02"},{"v":0.003984,"d":"0.00"},{"v":0.008792,"d":"0.01"},{"v":0.068233,"d":"0.07"},{"v":2.39049982100754,"d":"2.39"},{"v":1.25731229766154,"d":"1.26"},1,1,"up","no"]
[97905,0,"chr19","-",6677864,6679201,"ENST00000602229",3,585,"ENSG00000125730","C3","GO:0001798(positive regulation of type IIa hypersensitivity);GO:0001934(positive regulation of protein phosphorylation);GO:0001970(positive regulation of activation of membrane attack complex);GO:0002376(immune system process);GO:0004866(endopeptidase inhibitor activity);GO:0005102(signaling receptor binding);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0005615(extracellular space);GO:0005788(endoplasmic reticulum lumen);GO:0005886(plasma membrane);GO:0006629(lipid metabolic process);GO:0006631(fatty acid metabolic process);GO:0006954(inflammatory response);GO:0006955(immune response);GO:0006956(complement activation);GO:0006957(complement activation, alternative pathway);GO:0006958(complement activation, classical pathway);GO:0007165(signal transduction);GO:0007186(G protein-coupled receptor signaling pathway);GO:0009617(response to bacterium);GO:0009986(cell surface);GO:0010575(positive regulation of vascular endothelial growth factor production);GO:0010828(positive regulation of glucose transmembrane transport);GO:0010866(regulation of triglyceride biosynthetic process);GO:0010884(positive regulation of lipid storage);GO:0010951(negative regulation of endopeptidase activity);GO:0016322(neuron remodeling);GO:0030449(regulation of complement activation);GO:0031715(C5L2 anaphylatoxin chemotactic receptor binding);GO:0032991(protein-containing complex);GO:0034774(secretory granule lumen);GO:0035578(azurophil granule lumen);GO:0043312(neutrophil degranulation);GO:0043687(post-translational protein modification);GO:0044267(cellular protein metabolic process);GO:0045087(innate immune response);GO:0045745(positive regulation of G protein-coupled receptor signaling pathway);GO:0045766(positive regulation of angiogenesis);GO:0048260(positive regulation of receptor-mediated endocytosis);GO:0050766(positive regulation of phagocytosis);GO:0050776(regulation of immune response);GO:0060100(positive regulation of phagocytosis, engulfment);GO:0070062(extracellular exosome);GO:0072562(blood microparticle);GO:0097242(amyloid-beta clearance);GO:0097278(complement-dependent cytotoxicity);GO:0150062(complement-mediated synapse pruning);GO:0150064(vertebrate eye-specific patterning);GO:1905114(cell surface receptor signaling pathway involved in cell-cell signaling);GO:2000427(positive regulation of apoptotic cell clearance)","04080(Neuroactive ligand-receptor interaction);04145(Phagosome);04610(Complement and coagulation cascades);05133(Pertussis);05134(Legionellosis);05140(Leishmaniasis);05142(Chagas disease (American trypanosomiasis));05150(Staphylococcus aureus infection);05152(Tuberculosis);05167(Kaposi sarcoma-associated herpesvirus infection);05168(Herpes simplex virus 1 infection);05203(Viral carcinogenesis);05322(Systemic lupus erythematosus)","NA","NA","complement C3 [Source:HGNC Symbol;Acc:HGNC:1318]",{"v":0.017774,"d":"0.02"},{"v":0.046109,"d":"0.05"},{"v":0.041705,"d":"0.04"},{"v":0.005945,"d":"0.01"},{"v":0.028875,"d":"0.03"},{"v":0.005496,"d":"0.01"},{"v":2.61900982240302,"d":"2.62"},{"v":1.38902147041991,"d":"1.39"},1,1,"up","no"]
[22089,0,"chr10","-",73802596,73803344,"ENST00000429742",3,447,"ENSG00000166507","NDST2","GO:0000139(Golgi membrane);GO:0003824(catalytic activity);GO:0005794(Golgi apparatus);GO:0006024(glycosaminoglycan biosynthetic process);GO:0008146(sulfotransferase activity);GO:0008152(metabolic process);GO:0015012(heparan sulfate proteoglycan biosynthetic process);GO:0015014(heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process);GO:0015016([heparan sulfate]-glucosamine N-sulfotransferase activity);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016740(transferase activity);GO:0016787(hydrolase activity);GO:0019213(deacetylase activity);GO:0030210(heparin biosynthetic process);GO:0034483(heparan sulfate sulfotransferase activity);GO:0042328(heparan sulfate N-acetylglucosaminyltransferase activity)","00534(Glycosaminoglycan biosynthesis - heparan sulfate / heparin)","K02577","2.8.2.-;EC:3.1.1.-","N-deacetylase and N-sulfotransferase 2 [Source:HGNC Symbol;Acc:HGNC:7681]",{"v":0.023594,"d":"0.02"},{"v":0.483174,"d":"0.48"},{"v":0.088951,"d":"0.09"},{"v":0.018904,"d":"0.02"},{"v":0.183652,"d":"0.18"},{"v":0.446788,"d":"0.45"},{"v":0.917416654346541,"d":"0.92"},{"v":-0.124350997228691,"d":"-0.12"},1,1,"down","no"]
[44170,0,"chr12","+",56106162,56107219,"ENST00000551061",3,694,"ENSG00000170515","PA2G4","GO:0003676(nucleic acid binding);GO:0003677(DNA binding);GO:0003700(DNA-binding transcription factor activity);GO:0003723(RNA binding);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0005634(nucleus);GO:0005730(nucleolus);GO:0005737(cytoplasm);GO:0006364(rRNA processing);GO:0006417(regulation of translation);GO:0007050(cell cycle arrest);GO:0008283(cell population proliferation);GO:0016020(membrane);GO:0031625(ubiquitin protein ligase binding);GO:0035578(azurophil granule lumen);GO:0043066(negative regulation of apoptotic process);GO:0043312(neutrophil degranulation);GO:0045597(positive regulation of cell differentiation);GO:0045892(negative regulation of transcription, DNA-templated);GO:0070062(extracellular exosome)","NA","NA","NA","proliferation-associated 2G4 [Source:HGNC Symbol;Acc:HGNC:8550]",{"v":0.336407,"d":"0.34"},{"v":0.379227,"d":"0.38"},{"v":0.064679,"d":"0.06"},{"v":0.031377,"d":"0.03"},{"v":0.15525,"d":"0.16"},{"v":0.176398,"d":"0.18"},{"v":2.14947455409407,"d":"2.15"},{"v":1.10398403151238,"d":"1.10"},1,1,"up","no"]
[76466,0,"chr16","-",67657606,67660478,"ENST00000647559",12,1626,"ENSG00000102977","ACD","GO:0000723(telomere maintenance);GO:0000781(chromosome, telomeric region);GO:0000783(nuclear telomere cap complex);GO:0000784(nuclear chromosome, telomeric region);GO:0001501(skeletal system development);GO:0001655(urogenital system development);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005694(chromosome);GO:0006886(intracellular protein transport);GO:0016233(telomere capping);GO:0016604(nuclear body);GO:0030326(embryonic limb morphogenesis);GO:0031848(protection from non-homologous end joining at telomere);GO:0032202(telomere assembly);GO:0032211(negative regulation of telomere maintenance via telomerase);GO:0032212(positive regulation of telomere maintenance via telomerase);GO:0035282(segmentation);GO:0042162(telomeric DNA binding);GO:0044877(protein-containing complex binding);GO:0051973(positive regulation of telomerase activity);GO:0060381(positive regulation of single-stranded telomeric DNA binding);GO:0070182(DNA polymerase binding);GO:0070187(shelterin complex);GO:0070198(protein localization to chromosome, telomeric region);GO:0070200(establishment of protein localization to telomere);GO:1902496(protein binding involved in negative regulation of telomere maintenance via telomerase);GO:1902990(mitotic telomere maintenance via semi-conservative replication);GO:1905324(telomere-telomerase complex assembly)","NA","K11114","NA","ACD, shelterin complex subunit and telomerase recruitment factor [Source:HGNC Symbol;Acc:HGNC:25070]",0,0,0,0,0,0,1,0,1,1,"no","no"]
[152088,0,"chr4","+",73419547,73421219,"ENST00000495173",4,445,"ENSG00000163631","ALB","GO:0001895(retina homeostasis);GO:0002576(platelet degranulation);GO:0003677(DNA binding);GO:0005504(fatty acid binding);GO:0005507(copper ion binding);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0005615(extracellular space);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005783(endoplasmic reticulum);GO:0005788(endoplasmic reticulum lumen);GO:0005794(Golgi apparatus);GO:0006898(receptor-mediated endocytosis);GO:0008144(drug binding);GO:0008289(lipid binding);GO:0009267(cellular response to starvation);GO:0015643(toxic substance binding);GO:0016209(antioxidant activity);GO:0019825(oxygen binding);GO:0030170(pyridoxal phosphate binding);GO:0031093(platelet alpha granule lumen);GO:0032460(negative regulation of protein oligomerization);GO:0032991(protein-containing complex);GO:0034375(high-density lipoprotein particle remodeling);GO:0042802(identical protein binding);GO:0043066(negative regulation of apoptotic process);GO:0043069(negative regulation of programmed cell death);GO:0043687(post-translational protein modification);GO:0044267(cellular protein metabolic process);GO:0046872(metal ion binding);GO:0051087(chaperone binding);GO:0051659(maintenance of mitochondrion location);GO:0070062(extracellular exosome);GO:0072562(blood microparticle);GO:0098869(cellular oxidant detoxification);GO:0140272(exogenous protein binding)","04918(Thyroid hormone synthesis)","NA","NA","albumin [Source:HGNC Symbol;Acc:HGNC:399]",0,0,0,0,0,{"v":0.042402,"d":"0.04"},"-inf","-inf",1,1,"down","no"]
[141059,0,"chr3","-",56754981,57079329,"ENST00000477833",7,757,"ENSG00000163947","ARHGEF3","GO:0005085(guanyl-nucleotide exchange factor activity);GO:0005089(Rho guanyl-nucleotide exchange factor activity);GO:0005515(protein binding);GO:0005622(intracellular);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0007186(G protein-coupled receptor signaling pathway);GO:0007266(Rho protein signal transduction);GO:0035023(regulation of Rho protein signal transduction);GO:0035556(intracellular signal transduction);GO:0043065(positive regulation of apoptotic process);GO:0051056(regulation of small GTPase mediated signal transduction)","NA","K20683","NA","Rho guanine nucleotide exchange factor 3 [Source:HGNC Symbol;Acc:HGNC:683]",{"v":0.139289,"d":"0.14"},{"v":0.034594,"d":"0.03"},{"v":0.034262,"d":"0.03"},0,0,{"v":0.114659,"d":"0.11"},{"v":1.81533939769229,"d":"1.82"},{"v":0.860239301164396,"d":"0.86"},1,1,"up","no"]
[188984,0,"chr8","+",47157118,47157771,"ENST00000479243",1,654,"ENSG00000188873","RPL10AP2","NA","NA","NA","NA","ribosomal protein L10a pseudogene 2 [Source:HGNC Symbol;Acc:HGNC:31081]",{"v":0.064206,"d":"0.06"},0,0,{"v":0.041495,"d":"0.04"},{"v":0.059632,"d":"0.06"},0,{"v":0.634904624877629,"d":"0.63"},{"v":-0.655388207806418,"d":"-0.66"},1,1,"down","no"]
[186690,0,"chr8","-",12183121,12194133,"ENST00000530385",4,1171,"ENSG00000186523","FAM86B1","GO:0008168(methyltransferase activity);GO:0016740(transferase activity);GO:0032259(methylation)","NA","NA","NA","family with sequence similarity 86 member B1 [Source:HGNC Symbol;Acc:HGNC:28268]",0,0,0,0,0,0,1,0,1,1,"no","no"]
[82775,0,"chr17","+",19629451,19633825,"ENST00000452153",4,1150,"ENSG00000231625","SLC47A1P2","NA","NA","NA","NA","SLC47A1 pseudogene 2 [Source:HGNC Symbol;Acc:HGNC:53866]",{"v":0.012478,"d":"0.01"},0,{"v":0.003389,"d":"0.00"},0,0,{"v":0.00752,"d":"0.01"},{"v":2.10997340425532,"d":"2.11"},{"v":1.07722481419749,"d":"1.08"},1,1,"up","no"]
[48725,0,"chr12","-",120198756,120201089,"ENST00000552902",4,869,"ENSG00000089157","RPLP0","GO:0000027(ribosomal large subunit assembly);GO:0000184(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay);GO:0002181(cytoplasmic translation);GO:0003723(RNA binding);GO:0003735(structural constituent of ribosome);GO:0005515(protein binding);GO:0005622(intracellular);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005783(endoplasmic reticulum);GO:0005829(cytosol);GO:0005840(ribosome);GO:0005925(focal adhesion);GO:0006412(translation);GO:0006413(translational initiation);GO:0006614(SRP-dependent cotranslational protein targeting to membrane);GO:0014069(postsynaptic density);GO:0016020(membrane);GO:0019083(viral transcription);GO:0022625(cytosolic large ribosomal subunit);GO:0035722(interleukin-12-mediated signaling pathway);GO:0036464(cytoplasmic ribonucleoprotein granule);GO:0042254(ribosome biogenesis);GO:0070062(extracellular exosome);GO:0070180(large ribosomal subunit rRNA binding);GO:0098794(postsynapse);GO:1990904(ribonucleoprotein complex)","03010(Ribosome)","K02941","NA","ribosomal protein lateral stalk subunit P0 [Source:HGNC Symbol;Acc:HGNC:10371]",{"v":0.092485,"d":"0.09"},{"v":0.400323,"d":"0.40"},{"v":0.472659,"d":"0.47"},{"v":0.654413,"d":"0.65"},{"v":1.498088,"d":"1.50"},{"v":0.691973,"d":"0.69"},{"v":0.339418465417508,"d":"0.34"},{"v":-1.55886304078579,"d":"-1.56"},1,1,"down","no"]
[80790,0,"chr17","-",7260137,7263213,"ENST00000397317",5,1228,"ENSG00000181885","CLDN7","GO:0005198(structural molecule activity);GO:0005515(protein binding);GO:0005886(plasma membrane);GO:0005923(bicellular tight junction);GO:0007162(negative regulation of cell adhesion);GO:0008284(positive regulation of cell population proliferation);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016323(basolateral plasma membrane);GO:0016327(apicolateral plasma membrane);GO:0016328(lateral plasma membrane);GO:0016338(calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules);GO:0030054(cell junction);GO:0032463(negative regulation of protein homooligomerization);GO:0042802(identical protein binding);GO:0043066(negative regulation of apoptotic process);GO:0045471(response to ethanol);GO:0050839(cell adhesion molecule binding);GO:2000147(positive regulation of cell motility)","04514(Cell adhesion molecules (CAMs));04530(Tight junction);04670(Leukocyte transendothelial migration);05160(Hepatitis C)","K06087","NA","claudin 7 [Source:HGNC Symbol;Acc:HGNC:2049]",{"v":0.260614,"d":"0.26"},{"v":0.358955,"d":"0.36"},0,0,0,{"v":0.09548,"d":"0.10"},{"v":6.48899245915375,"d":"6.49"},{"v":2.69799448946876,"d":"2.70"},1,1,"up","no"]
[187050,0,"chr8","+",18084868,18088211,"ENST00000505114",4,451,"ENSG00000245281","AC124242","NA","NA","NA","NA","novel transcript",0,{"v":0.007941,"d":"0.01"},{"v":0.135474,"d":"0.14"},{"v":0.039492,"d":"0.04"},0,0,{"v":3.63149498632635,"d":"3.63"},{"v":1.86056358826202,"d":"1.86"},1,1,"up","no"]
[189595,0,"chr8","-",61576772,61689811,"ENST00000522349",5,531,"ENSG00000198363","ASPH","GO:0004597(peptide-aspartate beta-dioxygenase activity);GO:0005198(structural molecule activity);GO:0005509(calcium ion binding);GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005886(plasma membrane);GO:0006936(muscle contraction);GO:0007389(pattern specification process);GO:0008285(negative regulation of cell population proliferation);GO:0008307(structural constituent of muscle);GO:0009055(electron transfer activity);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016491(oxidoreductase activity);GO:0016529(sarcoplasmic reticulum);GO:0018193(peptidyl-amino acid modification);GO:0022900(electron transport chain);GO:0031647(regulation of protein stability);GO:0032541(cortical endoplasmic reticulum);GO:0033017(sarcoplasmic reticulum membrane);GO:0034220(ion transmembrane transport);GO:0035108(limb morphogenesis);GO:0042264(peptidyl-aspartic acid hydroxylation);GO:0045862(positive regulation of proteolysis);GO:0046872(metal ion binding);GO:0051213(dioxygenase activity);GO:0055114(oxidation-reduction process);GO:0060021(roof of mouth development);GO:0060325(face morphogenesis);GO:0062101(peptidyl-aspartic acid 3-dioxygenase activity);GO:0097202(activation of cysteine-type endopeptidase activity);GO:1901879(regulation of protein depolymerization);GO:1903779(regulation of cardiac conduction)","NA","NA","NA","aspartate beta-hydroxylase [Source:HGNC Symbol;Acc:HGNC:757]",{"v":0.082978,"d":"0.08"},0,{"v":0.17786,"d":"0.18"},0,{"v":0.07141,"d":"0.07"},{"v":0.084424,"d":"0.08"},{"v":1.67381957724245,"d":"1.67"},{"v":0.743144026666147,"d":"0.74"},1,1,"up","no"]
[135236,0,"chr22","-",42364402,42369208,"ENST00000412060",2,475,"ENSG00000229891","LINC01315","NA","NA","NA","NA","long intergenic non-protein coding RNA 1315 [Source:HGNC Symbol;Acc:HGNC:50513]",{"v":0.014465,"d":"0.01"},{"v":0.005077,"d":"0.01"},0,0,{"v":0.028621,"d":"0.03"},{"v":0.00391,"d":"0.00"},{"v":0.600719313885217,"d":"0.60"},{"v":-0.735237045808254,"d":"-0.74"},1,1,"down","no"]
[138409,0,"chr3","+",38496342,38524417,"ENST00000431472",7,1255,"ENSG00000157036","EXOG","GO:0000014(single-stranded DNA endodeoxyribonuclease activity);GO:0000737(DNA catabolic process, endonucleolytic);GO:0003676(nucleic acid binding);GO:0004518(nuclease activity);GO:0004519(endonuclease activity);GO:0004521(endoribonuclease activity);GO:0004529(exodeoxyribonuclease activity);GO:0005739(mitochondrion);GO:0005743(mitochondrial inner membrane);GO:0006309(apoptotic DNA fragmentation);GO:0008150(biological_process);GO:0008409(5'-3' exonuclease activity);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016787(hydrolase activity);GO:0032991(protein-containing complex);GO:0046872(metal ion binding);GO:0090502(RNA phosphodiester bond hydrolysis, endonucleolytic)","NA","K15050","NA","exo/endonuclease G [Source:HGNC Symbol;Acc:HGNC:3347]",{"v":0.006792,"d":"0.01"},0,0,0,0,0,"inf","inf",1,1,"up","no"]
[14762,0,"chr1","+",186171387,186189665,"ENST00000414277",6,720,"ENSG00000143341","HMCN1","GO:0005201(extracellular matrix structural constituent);GO:0005509(calcium ion binding);GO:0005576(extracellular region);GO:0005604(basement membrane);GO:0005737(cytoplasm);GO:0005913(cell-cell adherens junction);GO:0005938(cell cortex);GO:0007049(cell cycle);GO:0007156(homophilic cell adhesion via plasma membrane adhesion molecules);GO:0007157(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules);GO:0007601(visual perception);GO:0009617(response to bacterium);GO:0030054(cell junction);GO:0032154(cleavage furrow);GO:0038023(signaling receptor activity);GO:0042803(protein homodimerization activity);GO:0050839(cell adhesion molecule binding);GO:0050896(response to stimulus);GO:0051301(cell division);GO:0062023(collagen-containing extracellular matrix);GO:0070062(extracellular exosome)","NA","K17341","NA","hemicentin 1 [Source:HGNC Symbol;Acc:HGNC:19194]",{"v":1.080433,"d":"1.08"},{"v":1.129884,"d":"1.13"},{"v":0.937102,"d":"0.94"},{"v":0.604581,"d":"0.60"},{"v":0.799257,"d":"0.80"},{"v":0.745303,"d":"0.75"},{"v":1.46450093316353,"d":"1.46"},{"v":0.550409112486632,"d":"0.55"},1,1,"up","no"]
[95211,0,"chr18","+",58387711,58396580,"ENST00000588712",4,2066,"ENSG00000049759","NEDD4L","GO:0000122(negative regulation of transcription by RNA polymerase II);GO:0000209(protein polyubiquitination);GO:0003254(regulation of membrane depolarization);GO:0004842(ubiquitin-protein transferase activity);GO:0005515(protein binding);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0005768(endosome);GO:0005771(multivesicular body);GO:0005794(Golgi apparatus);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0006511(ubiquitin-dependent protein catabolic process);GO:0006513(protein monoubiquitination);GO:0006814(sodium ion transport);GO:0006883(cellular sodium ion homeostasis);GO:0007588(excretion);GO:0010038(response to metal ion);GO:0015459(potassium channel regulator activity);GO:0016032(viral process);GO:0016567(protein ubiquitination);GO:0016740(transferase activity);GO:0017080(sodium channel regulator activity);GO:0019058(viral life cycle);GO:0019870(potassium channel inhibitor activity);GO:0019871(sodium channel inhibitor activity);GO:0030104(water homeostasis);GO:0030154(cell differentiation);GO:0031647(regulation of protein stability);GO:0034220(ion transmembrane transport);GO:0034765(regulation of ion transmembrane transport);GO:0042176(regulation of protein catabolic process);GO:0042391(regulation of membrane potential);GO:0043161(proteasome-mediated ubiquitin-dependent protein catabolic process);GO:0044325(ion channel binding);GO:0045732(positive regulation of protein catabolic process);GO:0045807(positive regulation of endocytosis);GO:0048814(regulation of dendrite morphogenesis);GO:0060306(regulation of membrane repolarization);GO:0061630(ubiquitin protein ligase activity);GO:0070062(extracellular exosome);GO:0070936(protein K48-linked ubiquitination);GO:0086005(ventricular cardiac muscle cell action potential);GO:1901016(regulation of potassium ion transmembrane transporter activity);GO:1901017(negative regulation of potassium ion transmembrane transporter activity);GO:1901380(negative regulation of potassium ion transmembrane transport);GO:1902306(negative regulation of sodium ion transmembrane transport);GO:1903861(positive regulation of dendrite extension);GO:2000009(negative regulation of protein localization to cell surface);GO:2000650(negative regulation of sodium ion transmembrane transporter activity);GO:2001288(positive regulation of caveolin-mediated endocytosis)","04120(Ubiquitin mediated proteolysis);04144(Endocytosis);04530(Tight junction);04960(Aldosterone-regulated sodium reabsorption)","K13305","EC:2.3.2.26","neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase [Source:HGNC Symbol;Acc:HGNC:7728]",{"v":0.121601,"d":"0.12"},{"v":0.038654,"d":"0.04"},{"v":0.092483,"d":"0.09"},{"v":0.091919,"d":"0.09"},{"v":0.023842,"d":"0.02"},{"v":0.031301,"d":"0.03"},{"v":1.71858127864438,"d":"1.72"},{"v":0.781218084194516,"d":"0.78"},1,1,"up","no"]
[88642,0,"chr17","+",61383401,61384680,"ENST00000585495",3,716,"ENSG00000266934","AC005746","NA","NA","NA","NA","novel transcript, sense intronic to BCAS3",{"v":0.002703,"d":"0.00"},{"v":0.030732,"d":"0.03"},{"v":0.075135,"d":"0.08"},{"v":0.088073,"d":"0.09"},0,{"v":0.05106,"d":"0.05"},{"v":0.780332487619759,"d":"0.78"},{"v":-0.357839129843345,"d":"-0.36"},1,1,"down","no"]
[140077,0,"chr3","+",49720559,49721529,"ENST00000498376",3,746,"ENSG00000164068","RNF123","GO:0004842(ubiquitin-protein transferase activity);GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0016567(protein ubiquitination);GO:0016579(protein deubiquitination);GO:0016740(transferase activity);GO:0031965(nuclear membrane);GO:0046872(metal ion binding);GO:0051603(proteolysis involved in cellular protein catabolic process)","NA","K12169","EC:2.3.2.27","ring finger protein 123 [Source:HGNC Symbol;Acc:HGNC:21148]",{"v":0.769133,"d":"0.77"},{"v":0.205861,"d":"0.21"},{"v":0.279818,"d":"0.28"},{"v":0.119123,"d":"0.12"},{"v":0.254589,"d":"0.25"},{"v":0.233629,"d":"0.23"},{"v":2.06607490684805,"d":"2.07"},{"v":1.04689256096926,"d":"1.05"},1,1,"up","no"]
[154461,0,"chr4","-",119521000,119543297,"ENST00000512739",5,648,"ENSG00000138735","PDE5A","GO:0000166(nucleotide binding);GO:0003824(catalytic activity);GO:0004112(cyclic-nucleotide phosphodiesterase activity);GO:0004114(3',5'-cyclic-nucleotide phosphodiesterase activity);GO:0005515(protein binding);GO:0005575(cellular_component);GO:0005829(cytosol);GO:0007165(signal transduction);GO:0008081(phosphoric diester hydrolase activity);GO:0008152(metabolic process);GO:0010613(positive regulation of cardiac muscle hypertrophy);GO:0010749(regulation of nitric oxide mediated signal transduction);GO:0016787(hydrolase activity);GO:0030553(cGMP binding);GO:0042130(negative regulation of T cell proliferation);GO:0043406(positive regulation of MAP kinase activity);GO:0046068(cGMP metabolic process);GO:0046069(cGMP catabolic process);GO:0046872(metal ion binding);GO:0047555(3',5'-cyclic-GMP phosphodiesterase activity);GO:0055118(negative regulation of cardiac muscle contraction);GO:0055119(relaxation of cardiac muscle);GO:0060282(positive regulation of oocyte development)","00230(Purine metabolism);04022(cGMP-PKG signaling pathway)","K13762","EC:3.1.4.35","phosphodiesterase 5A [Source:HGNC Symbol;Acc:HGNC:8784]",0,0,{"v":0.030076,"d":"0.03"},{"v":0.06489,"d":"0.06"},0,0,{"v":0.463492063492063,"d":"0.46"},{"v":-1.10938345950726,"d":"-1.11"},1,1,"down","no"]
[15601,0,"chr1","-",204137213,204149881,"ENST00000444817",4,443,"ENSG00000143845","ETNK2","GO:0000166(nucleotide binding);GO:0001701(in utero embryonic development);GO:0001890(placenta development);GO:0004305(ethanolamine kinase activity);GO:0005524(ATP binding);GO:0005575(cellular_component);GO:0005829(cytosol);GO:0006629(lipid metabolic process);GO:0006646(phosphatidylethanolamine biosynthetic process);GO:0008150(biological_process);GO:0008654(phospholipid biosynthetic process);GO:0009791(post-embryonic development);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0016740(transferase activity);GO:0035264(multicellular organism growth)","00564(Glycerophospholipid metabolism)","K00894","EC:2.7.1.82","ethanolamine kinase 2 [Source:HGNC Symbol;Acc:HGNC:25575]",{"v":0.60137,"d":"0.60"},0,{"v":0.36713,"d":"0.37"},{"v":0.250886,"d":"0.25"},{"v":0.149183,"d":"0.15"},{"v":0.283966,"d":"0.28"},{"v":1.41586322337307,"d":"1.42"},{"v":0.50168190349135,"d":"0.50"},1,1,"up","no"]
[203548,0,"chrX","-",53992802,54002670,"ENST00000448003",5,403,"ENSG00000172943","PHF8","GO:0000082(G1/S transition of mitotic cell cycle);GO:0003682(chromatin binding);GO:0005506(iron ion binding);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005730(nucleolus);GO:0006325(chromatin organization);GO:0007049(cell cycle);GO:0007420(brain development);GO:0008270(zinc ion binding);GO:0016491(oxidoreductase activity);GO:0016706(2-oxoglutarate-dependent dioxygenase activity);GO:0031965(nuclear membrane);GO:0032452(histone demethylase activity);GO:0032454(histone demethylase activity (H3-K9 specific));GO:0033169(histone H3-K9 demethylation);GO:0035064(methylated histone binding);GO:0035574(histone H4-K20 demethylation);GO:0035575(histone demethylase activity (H4-K20 specific));GO:0045893(positive regulation of transcription, DNA-templated);GO:0045943(positive regulation of transcription by RNA polymerase I);GO:0046872(metal ion binding);GO:0051213(dioxygenase activity);GO:0051864(histone demethylase activity (H3-K36 specific));GO:0055114(oxidation-reduction process);GO:0061188(negative regulation of chromatin silencing at rDNA);GO:0070544(histone H3-K36 demethylation);GO:0071557(histone H3-K27 demethylation);GO:0071558(histone demethylase activity (H3-K27 specific))","NA","K19415","EC:1.14.11.27","PHD finger protein 8 [Source:HGNC Symbol;Acc:HGNC:20672]",{"v":0.004733,"d":"0.00"},{"v":0.004469,"d":"0.00"},{"v":0.043725,"d":"0.04"},{"v":0.045886,"d":"0.05"},{"v":0.001609,"d":"0.00"},{"v":0.124153,"d":"0.12"},{"v":0.308346150260999,"d":"0.31"},{"v":-1.69737726068116,"d":"-1.70"},1,1,"down","no"]
[44707,0,"chr12","+",57488056,57490342,"ENST00000550449",5,739,"ENSG00000166986","MARS","GO:0000049(tRNA binding);GO:0000166(nucleotide binding);GO:0003723(RNA binding);GO:0004812(aminoacyl-tRNA ligase activity);GO:0004825(methionine-tRNA ligase activity);GO:0005524(ATP binding);GO:0005634(nucleus);GO:0005730(nucleolus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0006412(translation);GO:0006418(tRNA aminoacylation for protein translation);GO:0006431(methionyl-tRNA aminoacylation);GO:0009267(cellular response to starvation);GO:0009303(rRNA transcription);GO:0016020(membrane);GO:0016874(ligase activity);GO:0017101(aminoacyl-tRNA synthetase multienzyme complex);GO:0032869(cellular response to insulin stimulus);GO:0036120(cellular response to platelet-derived growth factor stimulus);GO:0070062(extracellular exosome);GO:0071364(cellular response to epidermal growth factor stimulus);GO:1901838(positive regulation of transcription of nucleolar large rRNA by RNA polymerase I)","00450(Selenocompound metabolism);00970(Aminoacyl-tRNA biosynthesis)","K01874","EC:6.1.1.10","methionyl-tRNA synthetase [Source:HGNC Symbol;Acc:HGNC:6898]",0,{"v":0.035198,"d":"0.04"},0,{"v":0.217103,"d":"0.22"},{"v":0.20625,"d":"0.21"},{"v":0.148852,"d":"0.15"},{"v":0.0615129193208728,"d":"0.06"},{"v":-4.02296674383151,"d":"-4.02"},1,1,"down","no"]
[157717,0,"chr5","-",14741457,14749227,"ENST00000515517",3,615,"ENSG00000154122","ANKH","GO:0001501(skeletal system development);GO:0005315(inorganic phosphate transmembrane transporter activity);GO:0005886(plasma membrane);GO:0005887(integral component of plasma membrane);GO:0006817(phosphate ion transport);GO:0007626(locomotory behavior);GO:0015114(phosphate ion transmembrane transporter activity);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0019867(outer membrane);GO:0030500(regulation of bone mineralization);GO:0030504(inorganic diphosphate transmembrane transporter activity);GO:0030505(inorganic diphosphate transport);GO:0035435(phosphate ion transmembrane transport);GO:0055085(transmembrane transport)","NA","K22734","NA","ANKH inorganic pyrophosphate transport regulator [Source:HGNC Symbol;Acc:HGNC:15492]",{"v":0.000516,"d":"0.00"},{"v":0.000511,"d":"0.00"},{"v":0.002307,"d":"0.00"},{"v":0.000274,"d":"0.00"},{"v":0.00042,"d":"0.00"},{"v":0.000695,"d":"0.00"},{"v":2.40028797696184,"d":"2.40"},{"v":1.26320750500502,"d":"1.26"},1,1,"up","no"]
[111380,0,"chr2","-",36867398,36867495,"ENST00000516947",1,98,"ENSG00000252756","RNU6-577P","NA","NA","NA","NA","RNA, U6 small nuclear 577, pseudogene [Source:HGNC Symbol;Acc:HGNC:47540]",0,0,0,0,0,0,1,0,1,1,"no","no"]
[181920,0,"chr7","+",100120026,100122906,"ENST00000483756",4,721,"ENSG00000166997","CNPY4","GO:0003674(molecular_function);GO:0005102(signaling receptor binding);GO:0005576(extracellular region);GO:1903078(positive regulation of protein localization to plasma membrane)","NA","K22816","NA","canopy FGF signaling regulator 4 [Source:HGNC Symbol;Acc:HGNC:28631]",{"v":1.244081,"d":"1.24"},{"v":0.28422,"d":"0.28"},0,{"v":0.286835,"d":"0.29"},0,{"v":0.453444,"d":"0.45"},{"v":2.06449325186855,"d":"2.06"},{"v":1.04578770283878,"d":"1.05"},1,1,"up","no"]
[107597,0,"chr19","+",53197111,53211015,"ENST00000597550",5,545,"ENSG00000269001","AC092070","NA","NA","NA","NA","zinc finger protein pseudogene",0,{"v":0.287998,"d":"0.29"},{"v":0.213833,"d":"0.21"},{"v":0.099692,"d":"0.10"},{"v":0.344427,"d":"0.34"},{"v":0.126351,"d":"0.13"},{"v":0.879679913054148,"d":"0.88"},{"v":-0.184949425517023,"d":"-0.18"},1,1,"down","no"]
[66717,0,"chr15","-",75360955,75362391,"ENST00000563058",5,592,"ENSG00000140400","MAN2C1","GO:0003824(catalytic activity);GO:0004559(alpha-mannosidase activity);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005975(carbohydrate metabolic process);GO:0006013(mannose metabolic process);GO:0008152(metabolic process);GO:0009313(oligosaccharide catabolic process);GO:0016787(hydrolase activity);GO:0016798(hydrolase activity, acting on glycosyl bonds);GO:0030246(carbohydrate binding);GO:0046872(metal ion binding)","00511(Other glycan degradation)","K01191","EC:3.2.1.24","mannosidase alpha class 2C member 1 [Source:HGNC Symbol;Acc:HGNC:6827]",{"v":0.039757,"d":"0.04"},{"v":0.120223,"d":"0.12"},{"v":0.196126,"d":"0.20"},{"v":0.10504,"d":"0.11"},{"v":0.143614,"d":"0.14"},{"v":0.02503,"d":"0.03"},{"v":1.30115753935195,"d":"1.30"},{"v":0.379795648821324,"d":"0.38"},1,1,"up","no"]
[167012,0,"chr6","+",4928695,4943813,"ENST00000469671",4,732,"ENSG00000153046","CDYL","GO:0003682(chromatin binding);GO:0003714(transcription corepressor activity);GO:0003824(catalytic activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005694(chromosome);GO:0007283(spermatogenesis);GO:0007286(spermatid development);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016607(nuclear speck);GO:0016829(lyase activity);GO:0030154(cell differentiation);GO:0030674(protein binding, bridging);GO:0035064(methylated histone binding);GO:0060816(random inactivation of X chromosome);GO:0120092(crotonyl-CoA hydratase activity);GO:0120094(negative regulation of peptidyl-lysine crotonylation);GO:1903507(negative regulation of nucleic acid-templated transcription)","NA","K00653","EC:2.3.1.48","chromodomain Y like [Source:HGNC Symbol;Acc:HGNC:1811]",0,0,0,0,{"v":0.077368,"d":"0.08"},{"v":0.065277,"d":"0.07"},"-inf","-inf",1,1,"down","no"]
[142773,0,"chr3","+",111958039,111966703,"ENST00000470699",4,589,"ENSG00000144824","PHLDB2","GO:0000226(microtubule cytoskeleton organization);GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0005925(focal adhesion);GO:0010470(regulation of gastrulation);GO:0010717(regulation of epithelial to mesenchymal transition);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0031252(cell leading edge);GO:0045111(intermediate filament cytoskeleton);GO:0045180(basal cortex);GO:0045184(establishment of protein localization);GO:0045296(cadherin binding);GO:0051497(negative regulation of stress fiber assembly);GO:0051895(negative regulation of focal adhesion assembly);GO:0070507(regulation of microtubule cytoskeleton organization);GO:1903690(negative regulation of wound healing, spreading of epidermal cells);GO:1904261(positive regulation of basement membrane assembly involved in embryonic body morphogenesis)","NA","NA","NA","pleckstrin homology like domain family B member 2 [Source:HGNC Symbol;Acc:HGNC:29573]",{"v":0.211201,"d":"0.21"},{"v":0.254418,"d":"0.25"},{"v":0.354277,"d":"0.35"},{"v":0.031391,"d":"0.03"},0,{"v":0.005339,"d":"0.01"},{"v":22.3222433977675,"d":"22.32"},{"v":4.48041012098777,"d":"4.48"},1,1,"up","no"]
[139586,0,"chr3","-",48630714,48631400,"ENST00000485361",2,575,"ENSG00000225697","SLC26A6","GO:0005254(chloride channel activity);GO:0005783(endoplasmic reticulum);GO:0005886(plasma membrane);GO:0005887(integral component of plasma membrane);GO:0006811(ion transport);GO:0006820(anion transport);GO:0006821(chloride transport);GO:0008271(secondary active sulfate transmembrane transporter activity);GO:0008272(sulfate transport);GO:0008509(anion transmembrane transporter activity);GO:0012506(vesicle membrane);GO:0015106(bicarbonate transmembrane transporter activity);GO:0015108(chloride transmembrane transporter activity);GO:0015116(sulfate transmembrane transporter activity);GO:0015297(antiporter activity);GO:0015301(anion:anion antiporter activity);GO:0015499(formate transmembrane transporter activity);GO:0015562(efflux transmembrane transporter activity);GO:0015660(formate efflux transmembrane transporter activity);GO:0015701(bicarbonate transport);GO:0015724(formate transport);GO:0015797(mannitol transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016323(basolateral plasma membrane);GO:0016324(apical plasma membrane);GO:0019531(oxalate transmembrane transporter activity);GO:0019532(oxalate transport);GO:0030165(PDZ domain binding);GO:0030321(transepithelial chloride transport);GO:0030659(cytoplasmic vesicle membrane);GO:0031410(cytoplasmic vesicle);GO:0031526(brush border membrane);GO:0031982(vesicle);GO:0034707(chloride channel complex);GO:0042045(epithelial fluid transport);GO:0043231(intracellular membrane-bounded organelle);GO:0046724(oxalic acid secretion);GO:0048240(sperm capacitation);GO:0050892(intestinal absorption);GO:0051453(regulation of intracellular pH);GO:0051454(intracellular pH elevation);GO:0055085(transmembrane transport);GO:0070633(transepithelial transport);GO:0071320(cellular response to cAMP);GO:0071332(cellular response to fructose stimulus);GO:0071346(cellular response to interferon-gamma);GO:0097225(sperm midpiece);GO:0098656(anion transmembrane transport);GO:1902358(sulfate transmembrane transport);GO:1902476(chloride transmembrane transport);GO:2001150(positive regulation of dipeptide transmembrane transport)","04978(Mineral absorption)","K14704","NA","solute carrier family 26 member 6 [Source:HGNC Symbol;Acc:HGNC:14472]",{"v":0.095529,"d":"0.10"},{"v":0.31039,"d":"0.31"},{"v":0.074805,"d":"0.07"},{"v":0.40151,"d":"0.40"},{"v":0.064351,"d":"0.06"},{"v":0.203879,"d":"0.20"},{"v":0.717777047809598,"d":"0.72"},{"v":-0.478392303720957,"d":"-0.48"},1,1,"down","no"]
[76102,0,"chr16","-",66932065,66934402,"ENST00000422424",5,668,"ENSG00000166595","CIAO2B","GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0005819(spindle);GO:0005829(cytosol);GO:0005856(cytoskeleton);GO:0007059(chromosome segregation);GO:0016226(iron-sulfur cluster assembly);GO:0071817(MMXD complex);GO:0097361(CIA complex);GO:0097428(protein maturation by iron-sulfur cluster transfer);GO:0106035(protein maturation by [4Fe-4S] cluster transfer)","NA","NA","NA","cytosolic iron-sulfur assembly component 2B [Source:HGNC Symbol;Acc:HGNC:24261]",{"v":0.08008,"d":"0.08"},{"v":0.066061,"d":"0.07"},{"v":0.071441,"d":"0.07"},{"v":0.111717,"d":"0.11"},{"v":0.072484,"d":"0.07"},{"v":0.090659,"d":"0.09"},{"v":0.791610274321473,"d":"0.79"},{"v":-0.337137757620122,"d":"-0.34"},1,1,"down","no"]
[171562,0,"chr6","+",57532411,57587111,"ENST00000550475",3,375,"ENSG00000146143","PRIM2","GO:0000082(G1/S transition of mitotic cell cycle);GO:0003677(DNA binding);GO:0003697(single-stranded DNA binding);GO:0003896(DNA primase activity);GO:0003899(DNA-directed 5'-3' RNA polymerase activity);GO:0005654(nucleoplasm);GO:0005658(alpha DNA polymerase:primase complex);GO:0006260(DNA replication);GO:0006269(DNA replication, synthesis of RNA primer);GO:0006270(DNA replication initiation);GO:0016740(transferase activity);GO:0016779(nucleotidyltransferase activity);GO:0032201(telomere maintenance via semi-conservative replication);GO:0046872(metal ion binding);GO:0051536(iron-sulfur cluster binding);GO:0051539(4 iron, 4 sulfur cluster binding)","03030(DNA replication)","NA","NA","DNA primase subunit 2 [Source:HGNC Symbol;Acc:HGNC:9370]",0,0,0,0,{"v":0.211195,"d":"0.21"},0,"-inf","-inf",1,1,"down","no"]
[206729,0,"chrX","+",149544520,149549992,"ENST00000422892",5,1536,"ENSG00000197620","CXorf40A","GO:0005515(protein binding)","NA","NA","NA","chromosome X open reading frame 40A [Source:HGNC Symbol;Acc:HGNC:28089]",{"v":0.141604,"d":"0.14"},{"v":0.055844,"d":"0.06"},{"v":0.094789,"d":"0.09"},{"v":0.054007,"d":"0.05"},{"v":0.133467,"d":"0.13"},{"v":0.072667,"d":"0.07"},{"v":1.12337924433288,"d":"1.12"},{"v":0.167845052897733,"d":"0.17"},1,1,"up","no"]
[5657,0,"chr1","-",45496211,45499853,"ENST00000629670",4,919,"ENSG00000280670","CCDC163","GO:0016020(membrane);GO:0016021(integral component of membrane)","NA","NA","NA","coiled-coil domain containing 163 [Source:HGNC Symbol;Acc:HGNC:27003]",{"v":0.156431,"d":"0.16"},{"v":0.152193,"d":"0.15"},{"v":0.067582,"d":"0.07"},{"v":0.060374,"d":"0.06"},{"v":0.070168,"d":"0.07"},{"v":0.081936,"d":"0.08"},{"v":1.7705644819699,"d":"1.77"},{"v":0.824209386018687,"d":"0.82"},1,1,"up","no"]
[156844,0,"chr4","-",185626851,185656746,"ENST00000487836",6,723,"ENSG00000154556","SORBS2","GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0005200(structural constituent of cytoskeleton);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0005886(plasma membrane);GO:0005925(focal adhesion);GO:0007015(actin filament organization);GO:0007219(Notch signaling pathway);GO:0008093(cytoskeletal adaptor activity);GO:0008150(biological_process);GO:0008307(structural constituent of muscle);GO:0015629(actin cytoskeleton);GO:0016020(membrane);GO:0016324(apical plasma membrane);GO:0030018(Z disc);GO:0030027(lamellipodium);GO:0030054(cell junction);GO:0042995(cell projection);GO:0048471(perinuclear region of cytoplasm);GO:0061049(cell growth involved in cardiac muscle cell development)","NA","NA","NA","sorbin and SH3 domain containing 2 [Source:HGNC Symbol;Acc:HGNC:24098]",0,{"v":0.058196,"d":"0.06"},0,0,0,{"v":0.167589,"d":"0.17"},{"v":0.347254294732948,"d":"0.35"},{"v":-1.52593555776749,"d":"-1.53"},1,1,"down","no"]
[143164,0,"chr3","-",119211742,119240878,"ENST00000393765",8,2234,"ENSG00000121578","B4GALT4","GO:0000139(Golgi membrane);GO:0003945(N-acetyllactosamine synthase activity);GO:0005794(Golgi apparatus);GO:0005975(carbohydrate metabolic process);GO:0006486(protein glycosylation);GO:0006643(membrane lipid metabolic process);GO:0008378(galactosyltransferase activity);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016740(transferase activity);GO:0016757(transferase activity, transferring glycosyl groups);GO:0018146(keratan sulfate biosynthetic process);GO:0032580(Golgi cisterna membrane);GO:0046872(metal ion binding)","00533(Glycosaminoglycan biosynthesis - keratan sulfate);00601(Glycosphingolipid biosynthesis - lacto and neolacto series)","K07969","2.4.1.-;2.4.1.275;EC:2.4.1.90","beta-1,4-galactosyltransferase 4 [Source:HGNC Symbol;Acc:HGNC:927]",{"v":0.018228,"d":"0.02"},{"v":0.013038,"d":"0.01"},{"v":4.325755,"d":"4.33"},{"v":0.081757,"d":"0.08"},{"v":0.309997,"d":"0.31"},{"v":0.047737,"d":"0.05"},{"v":9.91378890580239,"d":"9.91"},{"v":3.30943653984573,"d":"3.31"},1,1,"up","no"]
[63358,0,"chr15","+",42559384,42561687,"ENST00000607467",2,443,"ENSG00000137814","HAUS2","GO:0000086(G2/M transition of mitotic cell cycle);GO:0003674(molecular_function);GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0005813(centrosome);GO:0005815(microtubule organizing center);GO:0005819(spindle);GO:0005829(cytosol);GO:0005856(cytoskeleton);GO:0005874(microtubule);GO:0005876(spindle microtubule);GO:0007049(cell cycle);GO:0007098(centrosome cycle);GO:0010389(regulation of G2/M transition of mitotic cell cycle);GO:0031023(microtubule organizing center organization);GO:0051225(spindle assembly);GO:0051301(cell division);GO:0070652(HAUS complex);GO:0097711(ciliary basal body-plasma membrane docking)","NA","K16585","NA","HAUS augmin like complex subunit 2 [Source:HGNC Symbol;Acc:HGNC:25530]",{"v":0.056408,"d":"0.06"},{"v":0.042857,"d":"0.04"},{"v":0.00072,"d":"0.00"},{"v":0.094363,"d":"0.09"},{"v":0.001775,"d":"0.00"},{"v":0.001176,"d":"0.00"},{"v":1.0274472326695,"d":"1.03"},{"v":0.0390643023051535,"d":"0.04"},1,1,"up","no"]
[202422,0,"chrX","-",40713878,40715051,"ENST00000492219",2,545,"ENSG00000180182","MED14","GO:0003712(transcription coregulator activity);GO:0003713(transcription coactivator activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0006357(regulation of transcription by RNA polymerase II);GO:0006367(transcription initiation from RNA polymerase II promoter);GO:0016020(membrane);GO:0016592(mediator complex);GO:0019827(stem cell population maintenance);GO:0030374(nuclear receptor transcription coactivator activity);GO:0042809(vitamin D receptor binding);GO:0045893(positive regulation of transcription, DNA-templated);GO:0045944(positive regulation of transcription by RNA polymerase II);GO:0070847(core mediator complex)","04919(Thyroid hormone signaling pathway)","K15156","NA","mediator complex subunit 14 [Source:HGNC Symbol;Acc:HGNC:2370]",{"v":0.166943,"d":"0.17"},{"v":0.083895,"d":"0.08"},{"v":0.038763,"d":"0.04"},{"v":0.085409,"d":"0.09"},{"v":0.000698,"d":"0.00"},{"v":0.079689,"d":"0.08"},{"v":1.7467309223383,"d":"1.75"},{"v":0.804657383350951,"d":"0.80"},1,1,"up","no"]
[52512,0,"chr13","+",76995229,76996277,"ENST00000636602",2,661,"ENSG00000102805","CLN5","GO:0005515(protein binding);GO:0005537(mannose binding);GO:0005764(lysosome);GO:0005765(lysosomal membrane);GO:0005783(endoplasmic reticulum);GO:0005794(Golgi apparatus);GO:0005829(cytosol);GO:0006465(signal peptide processing);GO:0007042(lysosomal lumen acidification);GO:0007420(brain development);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0022008(neurogenesis);GO:0030163(protein catabolic process);GO:0042147(retrograde transport, endosome to Golgi);GO:0042551(neuron maturation);GO:0048471(perinuclear region of cytoplasm);GO:0070062(extracellular exosome);GO:0070085(glycosylation);GO:1904426(positive regulation of GTP binding)","04142(Lysosome)","K12390","NA","CLN5, intracellular trafficking protein [Source:HGNC Symbol;Acc:HGNC:2076]",{"v":0.083701,"d":"0.08"},0,0,0,0,0,"inf","inf",1,1,"up","no"]
[179927,0,"chr7","+",73683607,73705161,"ENST00000436944",10,2496,"ENSG00000071462","BUD23","GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005730(nucleolus);GO:0005737(cytoplasm);GO:0006325(chromatin organization);GO:0006364(rRNA processing);GO:0008168(methyltransferase activity);GO:0016435(rRNA (guanine) methyltransferase activity);GO:0016740(transferase activity);GO:0031167(rRNA methylation);GO:0032259(methylation);GO:0042254(ribosome biogenesis);GO:0046982(protein heterodimerization activity);GO:0048471(perinuclear region of cytoplasm);GO:0070476(rRNA (guanine-N7)-methylation);GO:2000234(positive regulation of rRNA processing)","NA","K19306","EC:2.1.1.309","BUD23, rRNA methyltransferase and ribosome maturation factor [Source:HGNC Symbol;Acc:HGNC:16405]",{"v":0.058881,"d":"0.06"},{"v":0.053452,"d":"0.05"},{"v":0.119831,"d":"0.12"},{"v":0.136095,"d":"0.14"},{"v":0.068391,"d":"0.07"},{"v":0.014067,"d":"0.01"},{"v":1.06227779989293,"d":"1.06"},{"v":0.0871610995870593,"d":"0.09"},1,1,"up","no"]
[45204,0,"chr12","+",64464355,64490452,"ENST00000651889",10,1573,"ENSG00000183735","TBK1","GO:0000166(nucleotide binding);GO:0002218(activation of innate immune response);GO:0002376(immune system process);GO:0003676(nucleic acid binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005515(protein binding);GO:0005524(ATP binding);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0006468(protein phosphorylation);GO:0006954(inflammatory response);GO:0007249(I-kappaB kinase/NF-kappaB signaling);GO:0009615(response to virus);GO:0010008(endosome membrane);GO:0010468(regulation of gene expression);GO:0010629(negative regulation of gene expression);GO:0016032(viral process);GO:0016235(aggresome);GO:0016239(positive regulation of macroautophagy);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0016740(transferase activity);GO:0018105(peptidyl-serine phosphorylation);GO:0018107(peptidyl-threonine phosphorylation);GO:0019903(protein phosphatase binding);GO:0031323(regulation of cellular metabolic process);GO:0032479(regulation of type I interferon production);GO:0032480(negative regulation of type I interferon production);GO:0032481(positive regulation of type I interferon production);GO:0032606(type I interferon production);GO:0032727(positive regulation of interferon-alpha production);GO:0032728(positive regulation of interferon-beta production);GO:0033138(positive regulation of peptidyl-serine phosphorylation);GO:0035666(TRIF-dependent toll-like receptor signaling pathway);GO:0042802(identical protein binding);GO:0043123(positive regulation of I-kappaB kinase/NF-kappaB signaling);GO:0044565(dendritic cell proliferation);GO:0045087(innate immune response);GO:0045359(positive regulation of interferon-beta biosynthetic process);GO:0045944(positive regulation of transcription by RNA polymerase II);GO:0050830(defense response to Gram-positive bacterium);GO:0051219(phosphoprotein binding);GO:0051607(defense response to virus);GO:0060340(positive regulation of type I interferon-mediated signaling pathway);GO:0071345(cellular response to cytokine stimulus);GO:1901214(regulation of neuron death);GO:1904417(positive regulation of xenophagy)","04014(Ras signaling pathway);04137(Mitophagy - animal);04620(Toll-like receptor signaling pathway);04621(NOD-like receptor signaling pathway);04622(RIG-I-like receptor signaling pathway);04623(Cytosolic DNA-sensing pathway);04657(IL-17 signaling pathway);05160(Hepatitis C);05161(Hepatitis B);05162(Measles);05163(Human cytomegalovirus infection);05164(Influenza A);05165(Human papillomavirus infection);05167(Kaposi sarcoma-associated herpesvirus infection);05168(Herpes simplex virus 1 infection);05169(Epstein-Barr virus infection);05170(Human immunodeficiency virus 1 infection)","K05410","EC:2.7.11.10","TANK binding kinase 1 [Source:HGNC Symbol;Acc:HGNC:11584]",{"v":0.04731,"d":"0.05"},{"v":0.055477,"d":"0.06"},0,{"v":0.003981,"d":"0.00"},{"v":0.01649,"d":"0.02"},0,{"v":5.02110302378975,"d":"5.02"},{"v":2.32800432675557,"d":"2.33"},1,1,"up","no"]
[66441,0,"chr15","-",74632733,74635727,"ENST00000569606",2,533,"ENSG00000179151","EDC3","GO:0000932(P-body);GO:0003723(RNA binding);GO:0003729(mRNA binding);GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0016020(membrane);GO:0031087(deadenylation-independent decapping of nuclear-transcribed mRNA);GO:0033962(cytoplasmic mRNA processing body assembly);GO:0036464(cytoplasmic ribonucleoprotein granule);GO:0042802(identical protein binding);GO:0043928(exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay);GO:0090502(RNA phosphodiester bond hydrolysis, endonucleolytic);GO:1990174(phosphodiesterase decapping endonuclease activity)","03018(RNA degradation)","K12615","NA","enhancer of mRNA decapping 3 [Source:HGNC Symbol;Acc:HGNC:26114]",{"v":0.327866,"d":"0.33"},{"v":1.648998,"d":"1.65"},{"v":1.085495,"d":"1.09"},{"v":0.357297,"d":"0.36"},{"v":0.572288,"d":"0.57"},{"v":0.883442,"d":"0.88"},{"v":1.68908626291831,"d":"1.69"},{"v":0.756243009552267,"d":"0.76"},1,1,"up","no"]
[180547,0,"chr7","+",79456038,79459640,"ENST00000621901",2,937,"ENSG00000234456","MAGI2-AS3","NA","NA","NA","NA","MAGI2 antisense RNA 3 [Source:HGNC Symbol;Acc:HGNC:40862]",{"v":0.184807,"d":"0.18"},{"v":0.296955,"d":"0.30"},{"v":0.257342,"d":"0.26"},{"v":0.208609,"d":"0.21"},{"v":0.187169,"d":"0.19"},{"v":0.22623,"d":"0.23"},{"v":1.18825481344291,"d":"1.19"},{"v":0.248844245794389,"d":"0.25"},1,1,"up","no"]
[65781,0,"chr15","+",68833830,68834749,"ENST00000560974",1,920,"ENSG00000259286","AC087639","NA","NA","NA","NA","cytokine induced apoptosis inhibitor 1 (CIAPIN1)",0,0,0,0,0,{"v":0.065802,"d":"0.07"},"-inf","-inf",1,1,"down","no"]
[65401,0,"chr15","-",65118964,65119774,"ENST00000559051",2,557,"ENSG00000090470","PDCD7","GO:0000398(mRNA splicing, via spliceosome);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005689(U12-type spliceosomal complex);GO:0006915(apoptotic process);GO:0008380(RNA splicing);GO:0051384(response to glucocorticoid)","NA","NA","NA","programmed cell death 7 [Source:HGNC Symbol;Acc:HGNC:8767]",{"v":0.065286,"d":"0.07"},{"v":0.000121,"d":"0.00"},{"v":0.000123,"d":"0.00"},{"v":0.09233,"d":"0.09"},{"v":4.2e-5,"d":"0.00"},{"v":0.070775,"d":"0.07"},{"v":0.401662304547433,"d":"0.40"},{"v":-1.31594502208822,"d":"-1.32"},1,1,"down","no"]
[71674,0,"chr16","+",14258123,14262440,"ENST00000571770",3,696,"ENSG00000186260","MRTFB","GO:0003713(transcription coactivator activity);GO:0003779(actin binding);GO:0004864(protein phosphatase inhibitor activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0007275(multicellular organism development);GO:0007517(muscle organ development);GO:0030154(cell differentiation);GO:0032515(negative regulation of phosphoprotein phosphatase activity);GO:0045296(cadherin binding);GO:0045844(positive regulation of striated muscle tissue development);GO:0045944(positive regulation of transcription by RNA polymerase II);GO:0051145(smooth muscle cell differentiation)","NA","K22525","NA","myocardin related transcription factor B [Source:HGNC Symbol;Acc:HGNC:29819]",0,0,0,{"v":0.113936,"d":"0.11"},0,0,"-inf","-inf",1,1,"down","no"]
[156891,0,"chr4","-",185757042,185956368,"ENST00000476878",3,595,"ENSG00000154556","SORBS2","GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0005200(structural constituent of cytoskeleton);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0005886(plasma membrane);GO:0005925(focal adhesion);GO:0007015(actin filament organization);GO:0007219(Notch signaling pathway);GO:0008093(cytoskeletal adaptor activity);GO:0008150(biological_process);GO:0008307(structural constituent of muscle);GO:0015629(actin cytoskeleton);GO:0016020(membrane);GO:0016324(apical plasma membrane);GO:0030018(Z disc);GO:0030027(lamellipodium);GO:0030054(cell junction);GO:0042995(cell projection);GO:0048471(perinuclear region of cytoplasm);GO:0061049(cell growth involved in cardiac muscle cell development)","NA","NA","NA","sorbin and SH3 domain containing 2 [Source:HGNC Symbol;Acc:HGNC:24098]",0,{"v":0.073963,"d":"0.07"},0,0,{"v":0.045758,"d":"0.05"},0,{"v":1.61639494733161,"d":"1.62"},{"v":0.692779746938998,"d":"0.69"},1,1,"up","no"]
[27428,0,"chr11","-",9295096,9314633,"ENST00000533723",3,723,"ENSG00000166471","TMEM41B","GO:0000045(autophagosome assembly);GO:0005515(protein binding);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0006914(autophagy);GO:0007399(nervous system development);GO:0016020(membrane);GO:0016021(integral component of membrane)","NA","NA","NA","transmembrane protein 41B [Source:HGNC Symbol;Acc:HGNC:28948]",{"v":0.31516,"d":"0.32"},{"v":0.025725,"d":"0.03"},{"v":0.426777,"d":"0.43"},{"v":0.234313,"d":"0.23"},{"v":0.09079,"d":"0.09"},{"v":0.118856,"d":"0.12"},{"v":1.72912814021115,"d":"1.73"},{"v":0.790044786503055,"d":"0.79"},1,1,"up","no"]
[154738,0,"chr4","-",127920302,127965949,"ENST00000641658",11,1731,"ENSG00000164073","MFSD8","GO:0005215(transporter activity);GO:0005654(nucleoplasm);GO:0005764(lysosome);GO:0005765(lysosomal membrane);GO:0007040(lysosome organization);GO:0010506(regulation of autophagy);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0043231(intracellular membrane-bounded organelle);GO:0048666(neuron development);GO:0055085(transmembrane transport)","04142(Lysosome)","K12307","NA","major facilitator superfamily domain containing 8 [Source:HGNC Symbol;Acc:HGNC:28486]",0,0,0,0,0,{"v":0.016535,"d":"0.02"},"-inf","-inf",1,1,"down","no"]
[133311,0,"chr22","+",29310279,29311107,"ENST00000491016",3,646,"ENSG00000185340","GAS2L1","GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0005856(cytoskeleton);GO:0007050(cell cycle arrest);GO:0008017(microtubule binding);GO:0008093(cytoskeletal adaptor activity);GO:0009267(cellular response to starvation);GO:0046966(thyroid hormone receptor binding);GO:0097067(cellular response to thyroid hormone stimulus)","NA","NA","NA","growth arrest specific 2 like 1 [Source:HGNC Symbol;Acc:HGNC:16955]",{"v":0.030506,"d":"0.03"},{"v":0.088236,"d":"0.09"},{"v":0.076009,"d":"0.08"},{"v":0.05459,"d":"0.05"},{"v":0.023858,"d":"0.02"},{"v":0.049687,"d":"0.05"},{"v":1.51988917938112,"d":"1.52"},{"v":0.603966135388683,"d":"0.60"},1,1,"up","no"]
[131034,0,"chr21","+",44472895,44473739,"ENST00000443620",2,482,"ENSG00000223431","MTND6P21","NA","NA","NA","NA","MT-ND6 pseudogene 21 [Source:HGNC Symbol;Acc:HGNC:39639]",0,0,0,{"v":0.086928,"d":"0.09"},0,0,"-inf","-inf",1,1,"down","no"]
[181780,0,"chr7","-",99730573,99735196,"ENST00000467776",2,754,"ENSG00000160870","CYP3A7","GO:0002933(lipid hydroxylation);GO:0004497(monooxygenase activity);GO:0005506(iron ion binding);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0006805(xenobiotic metabolic process);GO:0008202(steroid metabolic process);GO:0008395(steroid hydroxylase activity);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016491(oxidoreductase activity);GO:0016705(oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen);GO:0016712(oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen);GO:0019825(oxygen binding);GO:0020037(heme binding);GO:0031090(organelle membrane);GO:0043231(intracellular membrane-bounded organelle);GO:0046872(metal ion binding);GO:0055114(oxidation-reduction process);GO:0070330(aromatase activity);GO:0101020(estrogen 16-alpha-hydroxylase activity)","00140(Steroid hormone biosynthesis);00830(Retinol metabolism);05204(Chemical carcinogenesis)","NA","NA","cytochrome P450 family 3 subfamily A member 7 [Source:HGNC Symbol;Acc:HGNC:2640]",{"v":0.03351,"d":"0.03"},0,0,0,0,0,"inf","inf",1,1,"up","no"]
[141300,0,"chr3","+",61561851,61751049,"ENST00000475527",2,2694,"ENSG00000144724","PTPRG","GO:0004721(phosphoprotein phosphatase activity);GO:0004725(protein tyrosine phosphatase activity);GO:0005001(transmembrane receptor protein tyrosine phosphatase activity);GO:0005515(protein binding);GO:0005615(extracellular space);GO:0005887(integral component of plasma membrane);GO:0006470(protein dephosphorylation);GO:0007169(transmembrane receptor protein tyrosine kinase signaling pathway);GO:0007420(brain development);GO:0010633(negative regulation of epithelial cell migration);GO:0010977(negative regulation of neuron projection development);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016311(dephosphorylation);GO:0016787(hydrolase activity);GO:0016791(phosphatase activity);GO:0035335(peptidyl-tyrosine dephosphorylation);GO:0042802(identical protein binding);GO:0070062(extracellular exosome)","NA","K16667","EC:3.1.3.48","protein tyrosine phosphatase, receptor type G [Source:HGNC Symbol;Acc:HGNC:9671]",{"v":0.06034,"d":"0.06"},{"v":6e-6,"d":"0.00"},{"v":0.016327,"d":"0.02"},{"v":0.008018,"d":"0.01"},{"v":0.03852,"d":"0.04"},{"v":5e-6,"d":"0.00"},{"v":1.64735835678835,"d":"1.65"},{"v":0.720154424721095,"d":"0.72"},1,1,"up","no"]
[173495,0,"chr6","-",118959829,119078647,"ENST00000621231",19,4048,"ENSG00000111879","FAM184A","GO:0003674(molecular_function);GO:0005515(protein binding);GO:0005615(extracellular space);GO:0008150(biological_process)","NA","NA","NA","family with sequence similarity 184 member A [Source:HGNC Symbol;Acc:HGNC:20991]",0,0,0,0,0,0,1,0,1,1,"no","no"]
[20382,0,"chr10","+",35247025,35516575,"ENST00000490012",10,793,"ENSG00000108100","CCNY","GO:0000079(regulation of cyclin-dependent protein serine/threonine kinase activity);GO:0000086(G2/M transition of mitotic cell cycle);GO:0000308(cytoplasmic cyclin-dependent protein kinase holoenzyme complex);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005886(plasma membrane);GO:0007049(cell cycle);GO:0016020(membrane);GO:0016055(Wnt signaling pathway);GO:0016538(cyclin-dependent protein serine/threonine kinase regulator activity);GO:0019901(protein kinase binding);GO:0045737(positive regulation of cyclin-dependent protein serine/threonine kinase activity);GO:0051301(cell division);GO:0060828(regulation of canonical Wnt signaling pathway)","NA","NA","NA","cyclin Y [Source:HGNC Symbol;Acc:HGNC:23354]",{"v":0.032531,"d":"0.03"},0,{"v":0.0496,"d":"0.05"},0,0,0,"inf","inf",1,1,"up","no"]
[123622,0,"chr2","+",237967014,238030595,"ENST00000448502",7,561,"ENSG00000184182","UBE2F","GO:0000166(nucleotide binding);GO:0005515(protein binding);GO:0005524(ATP binding);GO:0005829(cytosol);GO:0016740(transferase activity);GO:0019788(NEDD8 transferase activity);GO:0043687(post-translational protein modification);GO:0045116(protein neddylation);GO:0061654(NEDD8 conjugating enzyme activity)","04120(Ubiquitin mediated proteolysis)","K10687","EC:2.3.2.23","ubiquitin conjugating enzyme E2 F (putative) [Source:HGNC Symbol;Acc:HGNC:12480]",0,{"v":0.05127,"d":"0.05"},{"v":0.012647,"d":"0.01"},{"v":0.032768,"d":"0.03"},{"v":0.014885,"d":"0.01"},{"v":0.151314,"d":"0.15"},{"v":0.321244226429508,"d":"0.32"},{"v":-1.63825756922323,"d":"-1.64"},1,1,"down","no"]
[25792,0,"chr11","-",644233,687936,"ENST00000527170",10,1623,"ENSG00000177030","DEAF1","GO:0000122(negative regulation of transcription by RNA polymerase II);GO:0000977(RNA polymerase II regulatory region sequence-specific DNA binding);GO:0000981(DNA-binding transcription factor activity, RNA polymerase II-specific);GO:0001227(DNA-binding transcription repressor activity, RNA polymerase II-specific);GO:0001650(fibrillar center);GO:0001662(behavioral fear response);GO:0001843(neural tube closure);GO:0003677(DNA binding);GO:0003700(DNA-binding transcription factor activity);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0005634(nucleus);GO:0005667(transcription factor complex);GO:0005737(cytoplasm);GO:0006357(regulation of transcription by RNA polymerase II);GO:0006366(transcription by RNA polymerase II);GO:0007275(multicellular organism development);GO:0007281(germ cell development);GO:0007399(nervous system development);GO:0008542(visual learning);GO:0009653(anatomical structure morphogenesis);GO:0033599(regulation of mammary gland epithelial cell proliferation);GO:0045892(negative regulation of transcription, DNA-templated);GO:0045893(positive regulation of transcription, DNA-templated);GO:0046872(metal ion binding);GO:0048706(embryonic skeletal system development)","NA","K23041","NA","DEAF1 transcription factor [Source:HGNC Symbol;Acc:HGNC:14677]",0,0,{"v":0.249658,"d":"0.25"},0,{"v":0.007027,"d":"0.01"},{"v":2.07074,"d":"2.07"},{"v":0.120156879958147,"d":"0.12"},{"v":-3.05700883803563,"d":"-3.06"},1,1,"down","no"]
[59563,0,"chr14","+",92577295,92586580,"ENST00000555891",2,317,"ENSG00000100599","RIN3","GO:0005096(GTPase activator activity);GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0005768(endosome);GO:0005769(early endosome);GO:0005829(cytosol);GO:0006897(endocytosis);GO:0007165(signal transduction);GO:0017112(Rab guanyl-nucleotide exchange factor activity);GO:0017137(Rab GTPase binding);GO:0031410(cytoplasmic vesicle);GO:0043547(positive regulation of GTPase activity)","NA","NA","NA","Ras and Rab interactor 3 [Source:HGNC Symbol;Acc:HGNC:18751]",0,0,0,{"v":0.064454,"d":"0.06"},0,0,"-inf","-inf",1,1,"down","no"]
[106794,0,"chr19","-",50365880,50369331,"ENST00000597049",2,304,"ENSG00000269392","AC008655","NA","NA","NA","NA","novel transcript, antisense to NR1H2",{"v":0.164577,"d":"0.16"},0,{"v":0.297471,"d":"0.30"},{"v":0.138808,"d":"0.14"},{"v":0.248103,"d":"0.25"},0,{"v":1.19419711509882,"d":"1.19"},{"v":0.256040988616554,"d":"0.26"},1,1,"up","no"]
[152689,0,"chr4","-",82881902,82900569,"ENST00000507051",4,458,"ENSG00000138674","SEC31A","GO:0000139(Golgi membrane);GO:0002474(antigen processing and presentation of peptide antigen via MHC class I);GO:0005198(structural molecule activity);GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005829(cytosol);GO:0006886(intracellular protein transport);GO:0006888(endoplasmic reticulum to Golgi vesicle-mediated transport);GO:0007029(endoplasmic reticulum organization);GO:0012507(ER to Golgi transport vesicle membrane);GO:0015031(protein transport);GO:0016020(membrane);GO:0016192(vesicle-mediated transport);GO:0019886(antigen processing and presentation of exogenous peptide antigen via MHC class II);GO:0030120(vesicle coat);GO:0030127(COPII vesicle coat);GO:0030134(COPII-coated ER to Golgi transport vesicle);GO:0031410(cytoplasmic vesicle);GO:0036498(IRE1-mediated unfolded protein response);GO:0043231(intracellular membrane-bounded organelle);GO:0048208(COPII vesicle coating);GO:0048306(calcium-dependent protein binding);GO:0048471(perinuclear region of cytoplasm);GO:0051592(response to calcium ion);GO:0070971(endoplasmic reticulum exit site);GO:0090110(COPII-coated vesicle cargo loading);GO:0090114(COPII-coated vesicle budding)","04141(Protein processing in endoplasmic reticulum)","K14005","NA","SEC31 homolog A, COPII coat complex component [Source:HGNC Symbol;Acc:HGNC:17052]",{"v":0.126271,"d":"0.13"},0,0,0,0,0,"inf","inf",1,1,"up","no"]
[158685,0,"chr5","-",42807818,42811892,"ENST00000508937",2,606,"ENSG00000250722","SELENOP","GO:0001887(selenium compound metabolic process);GO:0002576(platelet degranulation);GO:0005576(extracellular region);GO:0005615(extracellular space);GO:0006979(response to oxidative stress);GO:0007420(brain development);GO:0007626(locomotory behavior);GO:0008430(selenium binding);GO:0009791(post-embryonic development);GO:0010269(response to selenium ion);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0019953(sexual reproduction);GO:0031089(platelet dense granule lumen);GO:0040008(regulation of growth);GO:0070062(extracellular exosome)","NA","NA","NA","selenoprotein P [Source:HGNC Symbol;Acc:HGNC:10751]",{"v":0.159825,"d":"0.16"},{"v":0.103255,"d":"0.10"},{"v":0.137604,"d":"0.14"},{"v":0.062641,"d":"0.06"},{"v":0.006542,"d":"0.01"},{"v":0.070627,"d":"0.07"},{"v":2.86591803161433,"d":"2.87"},{"v":1.51899734753634,"d":"1.52"},1,1,"up","no"]
[168595,0,"chr6","-",30304071,30306960,"ENST00000602516",1,2890,"ENSG00000231074","HCG18","NA","NA","NA","NA","HLA complex group 18 [Source:HGNC Symbol;Acc:HGNC:31337]",{"v":0.130715,"d":"0.13"},{"v":0.043532,"d":"0.04"},{"v":0.152139,"d":"0.15"},{"v":0.086193,"d":"0.09"},{"v":0.184405,"d":"0.18"},{"v":0.297179,"d":"0.30"},{"v":0.574848928364481,"d":"0.57"},{"v":-0.798745232631735,"d":"-0.80"},1,1,"down","no"]
[112525,0,"chr2","+",55314160,55339798,"ENST00000626053",4,780,"ENSG00000240401","AC012358","NA","NA","NA","NA","novel transcript, antisense to CCDC88A",0,0,0,0,{"v":0.124404,"d":"0.12"},0,"-inf","-inf",1,1,"down","no"]
[143333,0,"chr3","-",120674579,120682269,"ENST00000480862",3,656,"ENSG00000113924","HGD","GO:0004411(homogentisate 1,2-dioxygenase activity);GO:0005515(protein binding);GO:0005829(cytosol);GO:0006520(cellular amino acid metabolic process);GO:0006559(L-phenylalanine catabolic process);GO:0006570(tyrosine metabolic process);GO:0006572(tyrosine catabolic process);GO:0016491(oxidoreductase activity);GO:0042802(identical protein binding);GO:0046872(metal ion binding);GO:0051213(dioxygenase activity);GO:0055114(oxidation-reduction process);GO:0070062(extracellular exosome)","00350(Tyrosine metabolism)","NA","NA","homogentisate 1,2-dioxygenase [Source:HGNC Symbol;Acc:HGNC:4892]",0,0,0,{"v":0.017779,"d":"0.02"},0,0,"-inf","-inf",1,1,"down","no"]
[84369,0,"chr17","+",35498218,35499175,"ENST00000587542",1,958,"ENSG00000267369","AC015911","NA","NA","NA","NA","TAF5-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa (TAF5L) pseudogene",{"v":0.043831,"d":"0.04"},0,0,0,0,0,"inf","inf",1,1,"up","no"]
[46681,0,"chr12","+",95231412,95300634,"ENST00000397792",13,2484,"ENSG00000028203","VEZT","GO:0001669(acrosomal vesicle);GO:0002142(stereocilia ankle link complex);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0005912(adherens junction);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0017022(myosin binding);GO:0030054(cell junction);GO:0031410(cytoplasmic vesicle);GO:0042995(cell projection);GO:0060171(stereocilium membrane);GO:0098609(cell-cell adhesion)","NA","NA","NA","vezatin, adherens junctions transmembrane protein [Source:HGNC Symbol;Acc:HGNC:18258]",0,0,0,0,{"v":0.632162,"d":"0.63"},0,"-inf","-inf",1,1,"down","no"]
[122316,0,"chr2","+",219233667,219234416,"ENST00000468387",2,561,"ENSG00000163516","ANKZF1","GO:0003676(nucleic acid binding);GO:0004843(thiol-dependent ubiquitin-specific protease activity);GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0030433(ubiquitin-dependent ERAD pathway);GO:0036266(Cdc48p-Npl4p-Vms1p AAA ATPase complex);GO:0046872(metal ion binding);GO:0070301(cellular response to hydrogen peroxide);GO:0071630(nuclear protein quality control by the ubiquitin-proteasome system);GO:0072671(mitochondria-associated ubiquitin-dependent protein catabolic process)","NA","NA","NA","ankyrin repeat and zinc finger domain containing 1 [Source:HGNC Symbol;Acc:HGNC:25527]",{"v":0.141039,"d":"0.14"},{"v":0.167003,"d":"0.17"},{"v":0.472145,"d":"0.47"},{"v":0.274536,"d":"0.27"},{"v":0.425179,"d":"0.43"},{"v":0.166702,"d":"0.17"},{"v":0.900475175348591,"d":"0.90"},{"v":-0.151241590988069,"d":"-0.15"},1,1,"down","no"]
[32949,0,"chr11","+",67022719,67048939,"ENST00000525457",8,1678,"ENSG00000173227","SYT12","GO:0000149(SNARE binding);GO:0001786(phosphatidylserine binding);GO:0005509(calcium ion binding);GO:0005544(calcium-dependent phospholipid binding);GO:0005886(plasma membrane);GO:0014059(regulation of dopamine secretion);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016192(vesicle-mediated transport);GO:0017156(calcium ion regulated exocytosis);GO:0017158(regulation of calcium ion-dependent exocytosis);GO:0030054(cell junction);GO:0030276(clathrin binding);GO:0030672(synaptic vesicle membrane);GO:0031410(cytoplasmic vesicle);GO:0045202(synapse);GO:0046928(regulation of neurotransmitter secretion);GO:0048792(spontaneous exocytosis of neurotransmitter);GO:0060291(long-term synaptic potentiation);GO:0070382(exocytic vesicle);GO:0071277(cellular response to calcium ion)","NA","K19912","NA","synaptotagmin 12 [Source:HGNC Symbol;Acc:HGNC:18381]",0,0,0,0,0,0,1,0,1,1,"no","no"]
[19226,0,"chr10","-",13438484,13460083,"ENST00000486542",4,1764,"ENSG00000165626","BEND7","GO:0005515(protein binding);GO:0070062(extracellular exosome)","NA","NA","NA","BEN domain containing 7 [Source:HGNC Symbol;Acc:HGNC:23514]",0,{"v":0.013801,"d":"0.01"},0,0,0,0,"inf","inf",1,1,"up","no"]
[61802,0,"chr15","+",25108268,25108352,"ENST00000516468",1,85,"ENSG00000252277","SNORD116-30","NA","NA","NA","NA","small nucleolar RNA, C/D box 116-30 [Source:HGNC Symbol;Acc:HGNC:42797]",0,{"v":0.150549,"d":"0.15"},0,0,0,0,"inf","inf",1,1,"up","no"]
[58368,0,"chr14","+",73950308,73963112,"ENST00000554920",5,649,"ENSG00000119723","COQ6","GO:0004497(monooxygenase activity);GO:0005515(protein binding);GO:0005739(mitochondrion);GO:0005743(mitochondrial inner membrane);GO:0005794(Golgi apparatus);GO:0006744(ubiquinone biosynthetic process);GO:0016020(membrane);GO:0016491(oxidoreductase activity);GO:0016709(oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen);GO:0016712(oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen);GO:0031314(extrinsic component of mitochondrial inner membrane);GO:0042995(cell projection);GO:0050660(flavin adenine dinucleotide binding);GO:0055114(oxidation-reduction process);GO:0071949(FAD binding)","00130(Ubiquinone and other terpenoid-quinone biosynthesis)","K06126","EC:1.14.13.-","coenzyme Q6, monooxygenase [Source:HGNC Symbol;Acc:HGNC:20233]",0,0,{"v":0.012716,"d":"0.01"},{"v":0.106614,"d":"0.11"},0,{"v":0.196392,"d":"0.20"},{"v":0.0419661656864881,"d":"0.04"},{"v":-4.57462953493284,"d":"-4.57"},1,1,"down","no"]
[110128,0,"chr2","-",16552936,16665828,"ENST00000406434",13,1386,"ENSG00000197872","FAM49A","GO:0005622(intracellular)","NA","NA","NA","family with sequence similarity 49 member A [Source:HGNC Symbol;Acc:HGNC:25373]",{"v":0.03224,"d":"0.03"},0,0,{"v":0.041326,"d":"0.04"},0,{"v":0.274794,"d":"0.27"},{"v":0.101986587371884,"d":"0.10"},{"v":-3.29354866430264,"d":"-3.29"},1,1,"down","no"]
[140331,0,"chr3","-",50326356,50328195,"ENST00000417867",3,561,"ENSG00000114383","TUSC2","GO:0001779(natural killer cell differentiation);GO:0005515(protein binding);GO:0005739(mitochondrion);GO:0006909(phagocytosis);GO:0006954(inflammatory response);GO:0007049(cell cycle);GO:0032618(interleukin-15 production);GO:0032700(negative regulation of interleukin-17 production);GO:0032733(positive regulation of interleukin-10 production);GO:0048469(cell maturation);GO:0050829(defense response to Gram-negative bacterium);GO:0051881(regulation of mitochondrial membrane potential);GO:0052567(response to defense-related host reactive oxygen species production);GO:0070945(neutrophil mediated killing of gram-negative bacterium);GO:0071609(chemokine (C-C motif) ligand 5 production);GO:2000377(regulation of reactive oxygen species metabolic process)","NA","NA","NA","tumor suppressor 2, mitochondrial calcium regulator [Source:HGNC Symbol;Acc:HGNC:17034]",0,0,{"v":0.018824,"d":"0.02"},0,{"v":0.00492,"d":"0.00"},{"v":0.101033,"d":"0.10"},{"v":0.177663681066133,"d":"0.18"},{"v":-2.49277930660498,"d":"-2.49"},1,1,"down","no"]
[124827,0,"chr20","-",5068483,5113087,"ENST00000612323",4,1231,"ENSG00000089063","TMEM230","GO:0005768(endosome);GO:0005769(early endosome);GO:0005770(late endosome);GO:0005776(autophagosome);GO:0005783(endoplasmic reticulum);GO:0005794(Golgi apparatus);GO:0005802(trans-Golgi network);GO:0008021(synaptic vesicle);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0030054(cell junction);GO:0031410(cytoplasmic vesicle);GO:0045202(synapse);GO:0048489(synaptic vesicle transport);GO:0055037(recycling endosome)","NA","NA","NA","transmembrane protein 230 [Source:HGNC Symbol;Acc:HGNC:15876]",{"v":0.094644,"d":"0.09"},{"v":0.173059,"d":"0.17"},0,{"v":0.059349,"d":"0.06"},0,{"v":0.056875,"d":"0.06"},{"v":2.30333666024229,"d":"2.30"},{"v":1.20372529370349,"d":"1.20"},1,1,"up","no"]
[79411,0,"chr17","-",673696,675667,"ENST00000575100",1,1972,"ENSG00000141252","VPS53","GO:0000938(GARP complex);GO:0005515(protein binding);GO:0005768(endosome);GO:0005794(Golgi apparatus);GO:0005802(trans-Golgi network);GO:0005829(cytosol);GO:0007041(lysosomal transport);GO:0010008(endosome membrane);GO:0015031(protein transport);GO:0016020(membrane);GO:0032456(endocytic recycling);GO:0032588(trans-Golgi network membrane);GO:0042147(retrograde transport, endosome to Golgi);GO:0048471(perinuclear region of cytoplasm);GO:0055037(recycling endosome);GO:1990745(EARP complex)","NA","K20299","NA","VPS53, GARP complex subunit [Source:HGNC Symbol;Acc:HGNC:25608]",{"v":0.148978,"d":"0.15"},{"v":0.212165,"d":"0.21"},{"v":0.061908,"d":"0.06"},{"v":0.148276,"d":"0.15"},{"v":0.147765,"d":"0.15"},{"v":0.112349,"d":"0.11"},{"v":1.0358995078234,"d":"1.04"},{"v":0.0508840545719582,"d":"0.05"},1,1,"up","no"]
[155877,0,"chr4","+",156972631,156972956,"ENST00000508378",1,326,"ENSG00000250622","AC093325","NA","NA","NA","NA","ribosomal protein L34 (RPL34) pseudogene",0,{"v":0.117282,"d":"0.12"},0,0,0,0,"inf","inf",1,1,"up","no"]
[199242,0,"chr9","+",127612207,127692716,"ENST00000373302",20,3967,"ENSG00000136854","STXBP1","GO:0000149(SNARE binding);GO:0002576(platelet degranulation);GO:0003006(developmental process involved in reproduction);GO:0003723(RNA binding);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0005739(mitochondrion);GO:0005829(cytosol);GO:0005856(cytoskeleton);GO:0005886(plasma membrane);GO:0006887(exocytosis);GO:0006904(vesicle docking involved in exocytosis);GO:0007269(neurotransmitter secretion);GO:0007274(neuromuscular synaptic transmission);GO:0007412(axon target recognition);GO:0010807(regulation of synaptic vesicle priming);GO:0014047(glutamate secretion);GO:0015031(protein transport);GO:0016020(membrane);GO:0016082(synaptic vesicle priming);GO:0016188(synaptic vesicle maturation);GO:0016192(vesicle-mediated transport);GO:0017075(syntaxin-1 binding);GO:0019901(protein kinase binding);GO:0019904(protein domain specific binding);GO:0019905(syntaxin binding);GO:0030424(axon);GO:0031091(platelet alpha granule);GO:0031333(negative regulation of protein complex assembly);GO:0031338(regulation of vesicle fusion);GO:0031630(regulation of synaptic vesicle fusion to presynaptic active zone membrane);GO:0032229(negative regulation of synaptic transmission, GABAergic);GO:0032355(response to estradiol);GO:0032991(protein-containing complex);GO:0035542(regulation of SNARE complex assembly);GO:0042802(identical protein binding);GO:0043274(phospholipase binding);GO:0043306(positive regulation of mast cell degranulation);GO:0043524(negative regulation of neuron apoptotic process);GO:0045335(phagocytic vesicle);GO:0045921(positive regulation of exocytosis);GO:0045956(positive regulation of calcium ion-dependent exocytosis);GO:0047485(protein N-terminus binding);GO:0048471(perinuclear region of cytoplasm);GO:0048787(presynaptic active zone membrane);GO:0050821(protein stabilization);GO:0060292(long-term synaptic depression);GO:0070062(extracellular exosome);GO:0070527(platelet aggregation);GO:0071346(cellular response to interferon-gamma);GO:0072659(protein localization to plasma membrane);GO:0098793(presynapse);GO:0098794(postsynapse);GO:0098978(glutamatergic synapse);GO:0099525(presynaptic dense core vesicle exocytosis);GO:0106022(positive regulation of vesicle docking);GO:1903296(positive regulation of glutamate secretion, neurotransmission)","04721(Synaptic vesicle cycle)","K15292","NA","syntaxin binding protein 1 [Source:HGNC Symbol;Acc:HGNC:11444]",0,{"v":0.001076,"d":"0.00"},{"v":0.005846,"d":"0.01"},{"v":0.476178,"d":"0.48"},0,{"v":0.002605,"d":"0.00"},{"v":0.0144574890921357,"d":"0.01"},{"v":-6.11203917613527,"d":"-6.11"},1,1,"down","no"]
[144033,0,"chr3","+",128879646,128913014,"ENST00000505867",17,2401,"ENSG00000177646","ACAD9","GO:0000062(fatty-acyl-CoA binding);GO:0001676(long-chain fatty acid metabolic process);GO:0003995(acyl-CoA dehydrogenase activity);GO:0004466(long-chain-acyl-CoA dehydrogenase activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005739(mitochondrion);GO:0005743(mitochondrial inner membrane);GO:0016491(oxidoreductase activity);GO:0016627(oxidoreductase activity, acting on the CH-CH group of donors);GO:0017099(very-long-chain-acyl-CoA dehydrogenase activity);GO:0030425(dendrite);GO:0031966(mitochondrial membrane);GO:0032981(mitochondrial respiratory chain complex I assembly);GO:0050660(flavin adenine dinucleotide binding);GO:0051791(medium-chain fatty acid metabolic process);GO:0055114(oxidation-reduction process);GO:0070991(medium-chain-acyl-CoA dehydrogenase activity)","NA","K15980","EC:1.3.99.-","acyl-CoA dehydrogenase family member 9 [Source:HGNC Symbol;Acc:HGNC:21497]",0,0,0,0,0,0,1,0,1,1,"no","no"]
[106691,0,"chr19","-",49909700,49929435,"ENST00000594673",4,564,"ENSG00000213024","NUP62","GO:0000278(mitotic cell cycle);GO:0000922(spindle pole);GO:0003682(chromatin binding);GO:0005515(protein binding);GO:0005543(phospholipid binding);GO:0005634(nucleus);GO:0005635(nuclear envelope);GO:0005642(annulate lamellae);GO:0005643(nuclear pore);GO:0005737(cytoplasm);GO:0005813(centrosome);GO:0005815(microtubule organizing center);GO:0005856(cytoskeleton);GO:0006110(regulation of glycolytic process);GO:0006351(transcription, DNA-templated);GO:0006406(mRNA export from nucleus);GO:0006409(tRNA export from nucleus);GO:0006606(protein import into nucleus);GO:0006913(nucleocytoplasmic transport);GO:0007080(mitotic metaphase plate congression);GO:0007098(centrosome cycle);GO:0007100(mitotic centrosome separation);GO:0007166(cell surface receptor signaling pathway);GO:0007283(spermatogenesis);GO:0007569(cell aging);GO:0008219(cell death);GO:0008285(negative regulation of cell population proliferation);GO:0009755(hormone-mediated signaling pathway);GO:0009966(regulation of signal transduction);GO:0015031(protein transport);GO:0016032(viral process);GO:0016925(protein sumoylation);GO:0017056(structural constituent of nuclear pore);GO:0019083(viral transcription);GO:0019894(kinesin binding);GO:0030159(receptor signaling complex scaffold activity);GO:0030544(Hsp70 protein binding);GO:0031965(nuclear membrane);GO:0032991(protein-containing complex);GO:0042059(negative regulation of epidermal growth factor receptor signaling pathway);GO:0042169(SH2 domain binding);GO:0042306(regulation of protein import into nucleus);GO:0043066(negative regulation of apoptotic process);GO:0043069(negative regulation of programmed cell death);GO:0043123(positive regulation of I-kappaB kinase/NF-kappaB signaling);GO:0043130(ubiquitin binding);GO:0043407(negative regulation of MAP kinase activity);GO:0043657(host cell);GO:0044613(nuclear pore central transport channel);GO:0045742(positive regulation of epidermal growth factor receptor signaling pathway);GO:0045840(positive regulation of mitotic nuclear division);GO:0045893(positive regulation of transcription, DNA-templated);GO:0046578(regulation of Ras protein signal transduction);GO:0046580(negative regulation of Ras protein signal transduction);GO:0046601(positive regulation of centriole replication);GO:0046966(thyroid hormone receptor binding);GO:0051028(mRNA transport);GO:0051169(nuclear transport);GO:0051425(PTB domain binding);GO:0051879(Hsp90 protein binding);GO:0060236(regulation of mitotic spindle organization);GO:0060964(regulation of gene silencing by miRNA);GO:0070208(protein heterotrimerization);GO:0072686(mitotic spindle);GO:0075733(intracellular transport of virus);GO:0090543(Flemming body);GO:0098534(centriole assembly);GO:1900034(regulation of cellular response to heat);GO:1903438(positive regulation of mitotic cytokinetic process);GO:1904781(positive regulation of protein localization to centrosome);GO:1990904(ribonucleoprotein complex)","03013(RNA transport)","K14306","NA","nucleoporin 62 [Source:HGNC Symbol;Acc:HGNC:8066]",{"v":0.076573,"d":"0.08"},0,{"v":0.029978,"d":"0.03"},0,0,0,"inf","inf",1,1,"up","no"]
[12594,0,"chr1","+",156791376,156794804,"ENST00000459707",2,557,"ENSG00000143294","PRCC","GO:0000398(mRNA splicing, via spliceosome);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0007049(cell cycle);GO:0007093(mitotic cell cycle checkpoint);GO:0016607(nuclear speck)","05202(Transcriptional misregulation in cancer);05211(Renal cell carcinoma)","NA","NA","proline rich mitotic checkpoint control factor [Source:HGNC Symbol;Acc:HGNC:9343]",{"v":0.702919,"d":"0.70"},{"v":0.529642,"d":"0.53"},{"v":0.549872,"d":"0.55"},{"v":0.356526,"d":"0.36"},{"v":0.563348,"d":"0.56"},{"v":0.681713,"d":"0.68"},{"v":1.1129167506979,"d":"1.11"},{"v":0.154345679070513,"d":"0.15"},1,1,"up","no"]
[4271,0,"chr1","-",35460374,35557950,"ENST00000482929",8,1524,"ENSG00000142687","KIAA0319L","GO:0000139(Golgi membrane);GO:0005515(protein binding);GO:0005794(Golgi apparatus);GO:0005886(plasma membrane);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0031410(cytoplasmic vesicle)","NA","NA","NA","KIAA0319 like [Source:HGNC Symbol;Acc:HGNC:30071]",0,{"v":0.014438,"d":"0.01"},0,0,{"v":0.032784,"d":"0.03"},{"v":0.011659,"d":"0.01"},{"v":0.324865558130639,"d":"0.32"},{"v":-1.62208529596611,"d":"-1.62"},1,1,"down","no"]
[86463,0,"chr17","-",44903161,44915500,"ENST00000639277",10,1783,"ENSG00000131095","GFAP","GO:0005178(integrin binding);GO:0005198(structural molecule activity);GO:0005200(structural constituent of cytoskeleton);GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0005764(lysosome);GO:0005829(cytosol);GO:0005856(cytoskeleton);GO:0005882(intermediate filament);GO:0005883(neurofilament);GO:0009611(response to wounding);GO:0010625(positive regulation of Schwann cell proliferation);GO:0010977(negative regulation of neuron projection development);GO:0014002(astrocyte development);GO:0016020(membrane);GO:0019900(kinase binding);GO:0030198(extracellular matrix organization);GO:0031102(neuron projection regeneration);GO:0042802(identical protein binding);GO:0042995(cell projection);GO:0043254(regulation of protein complex assembly);GO:0044297(cell body);GO:0045103(intermediate filament-based process);GO:0045109(intermediate filament organization);GO:0045111(intermediate filament cytoskeleton);GO:0051580(regulation of neurotransmitter uptake);GO:0060020(Bergmann glial cell differentiation);GO:0060252(positive regulation of glial cell proliferation);GO:0060291(long-term synaptic potentiation);GO:0061564(axon development);GO:0097386(glial cell projection);GO:0097449(astrocyte projection);GO:0097450(astrocyte end-foot);GO:0098574(cytoplasmic side of lysosomal membrane);GO:1904714(regulation of chaperone-mediated autophagy)","04630(Jak-STAT signaling pathway)","NA","NA","glial fibrillary acidic protein [Source:HGNC Symbol;Acc:HGNC:4235]",0,0,0,0,0,0,1,0,1,1,"no","no"]
[136305,0,"chr3","-",4814305,4831349,"ENST00000489771",5,509,"ENSG00000235978","AC018816","NA","NA","NA","NA","novel transcript, antisense to ITPR1",0,0,0,{"v":0.019741,"d":"0.02"},0,0,"-inf","-inf",1,1,"down","no"]
[12561,0,"chr1","-",156727242,156728441,"ENST00000469074",2,594,"ENSG00000143319","ISG20L2","GO:0000175(3'-5'-exoribonuclease activity);GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0004518(nuclease activity);GO:0004527(exonuclease activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005730(nucleolus);GO:0006364(rRNA processing);GO:0016787(hydrolase activity);GO:0042254(ribosome biogenesis);GO:0090305(nucleic acid phosphodiester bond hydrolysis);GO:0090503(RNA phosphodiester bond hydrolysis, exonucleolytic)","NA","K18329","EC:3.1.-.-","interferon stimulated exonuclease gene 20 like 2 [Source:HGNC Symbol;Acc:HGNC:25745]",{"v":0.099134,"d":"0.10"},0,0,{"v":0.045352,"d":"0.05"},{"v":0.264078,"d":"0.26"},0,{"v":0.320376175548589,"d":"0.32"},{"v":-1.64216122771461,"d":"-1.64"},1,1,"down","no"]
[32200,0,"chr11","-",65130995,65133548,"ENST00000532771",8,709,"ENSG00000162298","SYVN1","GO:0000836(Hrd1p ubiquitin ligase complex);GO:0000839(Hrd1p ubiquitin ligase ERAD-L complex);GO:0005515(protein binding);GO:0005654(nucleoplasm);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005790(smooth endoplasmic reticulum);GO:0006511(ubiquitin-dependent protein catabolic process);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016567(protein ubiquitination);GO:0016740(transferase activity);GO:0018279(protein N-linked glycosylation via asparagine);GO:0030176(integral component of endoplasmic reticulum membrane);GO:0030433(ubiquitin-dependent ERAD pathway);GO:0030968(endoplasmic reticulum unfolded protein response);GO:0030970(retrograde protein transport, ER to cytosol);GO:0036498(IRE1-mediated unfolded protein response);GO:0036503(ERAD pathway);GO:0036513(Derlin-1 retrotranslocation complex);GO:0044322(endoplasmic reticulum quality control compartment);GO:0046872(metal ion binding);GO:0050821(protein stabilization);GO:0051082(unfolded protein binding);GO:0051087(chaperone binding);GO:0051117(ATPase binding);GO:0061630(ubiquitin protein ligase activity);GO:0070936(protein K48-linked ubiquitination);GO:1902236(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway);GO:1904380(endoplasmic reticulum mannose trimming);GO:1990381(ubiquitin-specific protease binding)","04120(Ubiquitin mediated proteolysis);04141(Protein processing in endoplasmic reticulum)","K10601","EC:2.3.2.27","synoviolin 1 [Source:HGNC Symbol;Acc:HGNC:20738]",0,0,0,{"v":0.301401,"d":"0.30"},0,0,"-inf","-inf",1,1,"down","no"]
[16074,0,"chr1","+",207770041,207793873,"ENST00000488596",6,872,"ENSG00000117335","CD46","GO:0001618(virus receptor activity);GO:0002079(inner acrosomal membrane);GO:0002250(adaptive immune response);GO:0002376(immune system process);GO:0002456(T cell mediated immunity);GO:0005515(protein binding);GO:0005886(plasma membrane);GO:0005887(integral component of plasma membrane);GO:0005925(focal adhesion);GO:0006958(complement activation, classical pathway);GO:0007338(single fertilization);GO:0008593(regulation of Notch signaling pathway);GO:0009986(cell surface);GO:0010628(positive regulation of gene expression);GO:0010629(negative regulation of gene expression);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016032(viral process);GO:0030449(regulation of complement activation);GO:0031410(cytoplasmic vesicle);GO:0032613(interleukin-10 production);GO:0032733(positive regulation of interleukin-10 production);GO:0035581(sequestering of extracellular ligand from receptor);GO:0038023(signaling receptor activity);GO:0042102(positive regulation of T cell proliferation);GO:0043382(positive regulation of memory T cell differentiation);GO:0045087(innate immune response);GO:0045296(cadherin binding);GO:0045591(positive regulation of regulatory T cell differentiation);GO:0046718(viral entry into host cell);GO:0070062(extracellular exosome);GO:0071636(positive regulation of transforming growth factor beta production)","04610(Complement and coagulation cascades);05162(Measles)","K04007","NA","CD46 molecule [Source:HGNC Symbol;Acc:HGNC:6953]",{"v":0.170495,"d":"0.17"},{"v":0.487355,"d":"0.49"},{"v":0.270607,"d":"0.27"},{"v":0.289704,"d":"0.29"},{"v":1.042511,"d":"1.04"},{"v":0.651519,"d":"0.65"},{"v":0.468035028889962,"d":"0.47"},{"v":-1.09531158620118,"d":"-1.10"},1,1,"down","no"]
[194603,0,"chr9","-",13106742,13165469,"ENST00000538841",25,3186,"ENSG00000107186","MPDZ","GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0005886(plasma membrane);GO:0005923(bicellular tight junction);GO:0007155(cell adhesion);GO:0008022(protein C-terminus binding);GO:0014069(postsynaptic density);GO:0016020(membrane);GO:0016032(viral process);GO:0016324(apical plasma membrane);GO:0016327(apicolateral plasma membrane);GO:0030054(cell junction);GO:0030425(dendrite);GO:0031410(cytoplasmic vesicle);GO:0042995(cell projection);GO:0043005(neuron projection);GO:0043220(Schmidt-Lanterman incisure);GO:0045202(synapse);GO:0045211(postsynaptic membrane)","04530(Tight junction)","K06095","NA","multiple PDZ domain crumbs cell polarity complex component [Source:HGNC Symbol;Acc:HGNC:7208]",{"v":0.387634,"d":"0.39"},0,0,0,0,0,"inf","inf",1,1,"up","no"]
[69122,0,"chr16","+",234834,261514,"ENST00000453430",7,984,"ENSG00000167930","FAM234A","GO:0003674(molecular_function);GO:0008150(biological_process);GO:0009986(cell surface);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0070062(extracellular exosome)","NA","K17258","NA","family with sequence similarity 234 member A [Source:HGNC Symbol;Acc:HGNC:14163]",0,0,0,{"v":0.05799,"d":"0.06"},0,{"v":0.018057,"d":"0.02"},"-inf","-inf",1,1,"down","no"]
[21224,0,"chr10","-",58325614,58327030,"ENST00000562575",1,1417,"ENSG00000261076","AC016396","NA","NA","NA","NA","novel transcript",{"v":0.059267,"d":"0.06"},0,{"v":0.030919,"d":"0.03"},{"v":0.029569,"d":"0.03"},{"v":0.10983,"d":"0.11"},{"v":0.031293,"d":"0.03"},{"v":0.528355166030042,"d":"0.53"},{"v":-0.920420044067861,"d":"-0.92"},1,1,"down","no"]
[99972,0,"chr19","-",14481747,14483463,"ENST00000587811",1,1717,"ENSG00000123159","GIPC1","GO:0003779(actin binding);GO:0005102(signaling receptor binding);GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005903(brush border);GO:0005938(cell cortex);GO:0006605(protein targeting);GO:0007186(G protein-coupled receptor signaling pathway);GO:0007268(chemical synaptic transmission);GO:0008021(synaptic vesicle);GO:0012506(vesicle membrane);GO:0014047(glutamate secretion);GO:0016020(membrane);GO:0017022(myosin binding);GO:0030139(endocytic vesicle);GO:0030165(PDZ domain binding);GO:0030511(positive regulation of transforming growth factor beta receptor signaling pathway);GO:0031410(cytoplasmic vesicle);GO:0031647(regulation of protein stability);GO:0032435(negative regulation of proteasomal ubiquitin-dependent protein catabolic process);GO:0032467(positive regulation of cytokinesis);GO:0042803(protein homodimerization activity);GO:0043197(dendritic spine);GO:0043198(dendritic shaft);GO:0043542(endothelial cell migration);GO:0045296(cadherin binding);GO:0048023(positive regulation of melanin biosynthetic process);GO:0048167(regulation of synaptic plasticity);GO:0070062(extracellular exosome);GO:0098685(Schaffer collateral - CA1 synapse);GO:0098761(cellular response to interleukin-7);GO:0098793(presynapse);GO:0098794(postsynapse);GO:0098978(glutamatergic synapse);GO:2000300(regulation of synaptic vesicle exocytosis)","NA","K20056","NA","GIPC PDZ domain containing family member 1 [Source:HGNC Symbol;Acc:HGNC:1226]",{"v":0.40587,"d":"0.41"},{"v":0.161168,"d":"0.16"},{"v":0.370302,"d":"0.37"},{"v":0.139123,"d":"0.14"},{"v":0.087175,"d":"0.09"},{"v":0.244827,"d":"0.24"},{"v":1.98957813743699,"d":"1.99"},{"v":0.992462559639444,"d":"0.99"},1,1,"up","no"]
[106048,0,"chr19","-",48662475,48673027,"ENST00000600468",5,2426,"ENSG00000142233","NTN5","GO:0005515(protein binding);GO:0005576(extracellular region);GO:0007275(multicellular organism development);GO:0007399(nervous system development);GO:0022008(neurogenesis)","NA","NA","NA","netrin 5 [Source:HGNC Symbol;Acc:HGNC:25208]",{"v":0.099305,"d":"0.10"},{"v":0.207182,"d":"0.21"},{"v":0.056224,"d":"0.06"},0,0,0,"inf","inf",1,1,"up","no"]
[99007,0,"chr19","+",11041439,11059845,"ENST00000645387",5,627,"ENSG00000127616","SMARCA4","GO:0000122(negative regulation of transcription by RNA polymerase II);GO:0000166(nucleotide binding);GO:0000790(nuclear chromatin);GO:0000978(RNA polymerase II proximal promoter sequence-specific DNA binding);GO:0000980(RNA polymerase II distal enhancer sequence-specific DNA binding);GO:0001164(RNA polymerase I CORE element sequence-specific DNA binding);GO:0001188(RNA polymerase I preinitiation complex assembly);GO:0002039(p53 binding);GO:0003407(neural retina development);GO:0003713(transcription coactivator activity);GO:0003714(transcription corepressor activity);GO:0003723(RNA binding);GO:0004386(helicase activity);GO:0005515(protein binding);GO:0005524(ATP binding);GO:0005615(extracellular space);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005730(nucleolus);GO:0006325(chromatin organization);GO:0006337(nucleosome disassembly);GO:0006338(chromatin remodeling);GO:0006355(regulation of transcription, DNA-templated);GO:0006357(regulation of transcription by RNA polymerase II);GO:0007399(nervous system development);GO:0008094(DNA-dependent ATPase activity);GO:0008134(transcription factor binding);GO:0016020(membrane);GO:0016514(SWI/SNF complex);GO:0016787(hydrolase activity);GO:0016817(hydrolase activity, acting on acid anhydrides);GO:0016887(ATPase activity);GO:0030177(positive regulation of Wnt signaling pathway);GO:0030308(negative regulation of cell growth);GO:0030957(Tat protein binding);GO:0031492(nucleosomal DNA binding);GO:0032991(protein-containing complex);GO:0038111(interleukin-7-mediated signaling pathway);GO:0042393(histone binding);GO:0043044(ATP-dependent chromatin remodeling);GO:0043923(positive regulation by host of viral transcription);GO:0045892(negative regulation of transcription, DNA-templated);GO:0045893(positive regulation of transcription, DNA-templated);GO:0045944(positive regulation of transcription by RNA polymerase II);GO:0047485(protein N-terminus binding);GO:0050681(androgen receptor binding);GO:0051091(positive regulation of DNA-binding transcription factor activity);GO:0060766(negative regulation of androgen receptor signaling pathway);GO:0070182(DNA polymerase binding);GO:0070577(lysine-acetylated histone binding);GO:0071564(npBAF complex);GO:0071565(nBAF complex);GO:1901838(positive regulation of transcription of nucleolar large rRNA by RNA polymerase I);GO:1902661(positive regulation of glucose mediated signaling pathway);GO:1902895(positive regulation of pri-miRNA transcription by RNA polymerase II);GO:1904837(beta-catenin-TCF complex assembly)","04714(Thermogenesis);05225(Hepatocellular carcinoma)","NA","NA","SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 [Source:HGNC Symbol;Acc:HGNC:11100]",{"v":0.007837,"d":"0.01"},0,{"v":0.011351,"d":"0.01"},0,0,0,"inf","inf",1,1,"up","no"]
[190904,0,"chr8","-",92014766,92095257,"ENST00000521375",4,596,"ENSG00000079102","RUNX1T1","GO:0003677(DNA binding);GO:0003700(DNA-binding transcription factor activity);GO:0003714(transcription corepressor activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0006091(generation of precursor metabolites and energy);GO:0006355(regulation of transcription, DNA-templated);GO:0016363(nuclear matrix);GO:0045599(negative regulation of fat cell differentiation);GO:0045892(negative regulation of transcription, DNA-templated);GO:0046872(metal ion binding)","05200(Pathways in cancer);05202(Transcriptional misregulation in cancer);05221(Acute myeloid leukemia)","NA","NA","RUNX1 translocation partner 1 [Source:HGNC Symbol;Acc:HGNC:1535]",0,0,0,{"v":0.007749,"d":"0.01"},0,0,"-inf","-inf",1,1,"down","no"]
[187504,0,"chr8","-",23191814,23197273,"ENST00000519862",2,342,"ENSG00000104689","TNFRSF10A","GO:0002020(protease binding);GO:0005035(death receptor activity);GO:0005515(protein binding);GO:0005886(plasma membrane);GO:0006915(apoptotic process);GO:0006919(activation of cysteine-type endopeptidase activity involved in apoptotic process);GO:0007165(signal transduction);GO:0007166(cell surface receptor signaling pathway);GO:0007250(activation of NF-kappaB-inducing kinase activity);GO:0008134(transcription factor binding);GO:0008625(extrinsic apoptotic signaling pathway via death domain receptors);GO:0009986(cell surface);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0036462(TRAIL-activated apoptotic signaling pathway);GO:0038023(signaling receptor activity);GO:0042981(regulation of apoptotic process);GO:0043065(positive regulation of apoptotic process);GO:0045569(TRAIL binding);GO:0050900(leukocyte migration);GO:0071260(cellular response to mechanical stimulus);GO:0097191(extrinsic apoptotic signaling pathway);GO:1902041(regulation of extrinsic apoptotic signaling pathway via death domain receptors);GO:1902042(negative regulation of extrinsic apoptotic signaling pathway via death domain receptors)","04060(Cytokine-cytokine receptor interaction);04210(Apoptosis);04217(Necroptosis);04650(Natural killer cell mediated cytotoxicity);05164(Influenza A)","K04722","NA","TNF receptor superfamily member 10a [Source:HGNC Symbol;Acc:HGNC:11904]",{"v":0.002275,"d":"0.00"},{"v":0.004785,"d":"0.00"},{"v":0.000751,"d":"0.00"},{"v":0.003159,"d":"0.00"},{"v":0.194165,"d":"0.19"},{"v":0.002668,"d":"0.00"},{"v":0.0390565622624905,"d":"0.04"},{"v":-4.67829122019983,"d":"-4.68"},1,1,"down","no"]
[198750,0,"chr9","-",120999677,121006928,"ENST00000466280",3,540,"ENSG00000106804","C5","GO:0000187(activation of MAPK activity);GO:0001701(in utero embryonic development);GO:0002376(immune system process);GO:0004866(endopeptidase inhibitor activity);GO:0005102(signaling receptor binding);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0005579(membrane attack complex);GO:0005615(extracellular space);GO:0006935(chemotaxis);GO:0006954(inflammatory response);GO:0006956(complement activation);GO:0006957(complement activation, alternative pathway);GO:0006958(complement activation, classical pathway);GO:0007166(cell surface receptor signaling pathway);GO:0007186(G protein-coupled receptor signaling pathway);GO:0008009(chemokine activity);GO:0010575(positive regulation of vascular endothelial growth factor production);GO:0010760(negative regulation of macrophage chemotaxis);GO:0010951(negative regulation of endopeptidase activity);GO:0019835(cytolysis);GO:0030449(regulation of complement activation);GO:0045087(innate immune response);GO:0045766(positive regulation of angiogenesis);GO:0060326(cell chemotaxis);GO:0070062(extracellular exosome);GO:0090197(positive regulation of chemokine secretion)","04080(Neuroactive ligand-receptor interaction);04610(Complement and coagulation cascades);05020(Prion diseases);05133(Pertussis);05150(Staphylococcus aureus infection);05168(Herpes simplex virus 1 infection);05322(Systemic lupus erythematosus)","NA","NA","complement C5 [Source:HGNC Symbol;Acc:HGNC:1331]",{"v":0.217583,"d":"0.22"},{"v":0.095614,"d":"0.10"},{"v":0.081423,"d":"0.08"},0,0,0,"inf","inf",1,1,"up","no"]
[39167,0,"chr12","-",6570191,6607419,"ENST00000644137",41,6499,"ENSG00000111642","CHD4","GO:0000122(negative regulation of transcription by RNA polymerase II);GO:0000166(nucleotide binding);GO:0000790(nuclear chromatin);GO:0000978(RNA polymerase II proximal promoter sequence-specific DNA binding);GO:0000980(RNA polymerase II distal enhancer sequence-specific DNA binding);GO:0001103(RNA polymerase II repressing transcription factor binding);GO:0003677(DNA binding);GO:0004003(ATP-dependent DNA helicase activity);GO:0004386(helicase activity);GO:0005515(protein binding);GO:0005524(ATP binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0005813(centrosome);GO:0005815(microtubule organizing center);GO:0005856(cytoskeleton);GO:0006325(chromatin organization);GO:0006357(regulation of transcription by RNA polymerase II);GO:0008134(transcription factor binding);GO:0008270(zinc ion binding);GO:0016020(membrane);GO:0016581(NuRD complex);GO:0016787(hydrolase activity);GO:0031492(nucleosomal DNA binding);GO:0032508(DNA duplex unwinding);GO:0032991(protein-containing complex);GO:0032993(protein-DNA complex);GO:0042826(histone deacetylase binding);GO:0043044(ATP-dependent chromatin remodeling);GO:0046872(metal ion binding);GO:0072553(terminal button organization);GO:1901796(regulation of signal transduction by p53 class mediator)","05165(Human papillomavirus infection);05203(Viral carcinogenesis)","NA","NA","chromodomain helicase DNA binding protein 4 [Source:HGNC Symbol;Acc:HGNC:1919]",0,0,0,0,{"v":0.021431,"d":"0.02"},0,"-inf","-inf",1,1,"down","no"]
[153992,0,"chr4","-",108063629,108167767,"ENST00000506680",11,1280,"ENSG00000138795","LEF1","GO:0000122(negative regulation of transcription by RNA polymerase II);GO:0000977(RNA polymerase II regulatory region sequence-specific DNA binding);GO:0000978(RNA polymerase II proximal promoter sequence-specific DNA binding);GO:0000981(DNA-binding transcription factor activity, RNA polymerase II-specific);GO:0001228(DNA-binding transcription activator activity, RNA polymerase II-specific);GO:0001569(branching involved in blood vessel morphogenesis);GO:0001649(osteoblast differentiation);GO:0001756(somitogenesis);GO:0001837(epithelial to mesenchymal transition);GO:0001944(vasculature development);GO:0002040(sprouting angiogenesis);GO:0003677(DNA binding);GO:0003682(chromatin binding);GO:0003700(DNA-binding transcription factor activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005667(transcription factor complex);GO:0005737(cytoplasm);GO:0006355(regulation of transcription, DNA-templated);GO:0006357(regulation of transcription by RNA polymerase II);GO:0006366(transcription by RNA polymerase II);GO:0007223(Wnt signaling pathway, calcium modulating pathway);GO:0008013(beta-catenin binding);GO:0008134(transcription factor binding);GO:0008284(positive regulation of cell population proliferation);GO:0008301(DNA binding, bending);GO:0010628(positive regulation of gene expression);GO:0010718(positive regulation of epithelial to mesenchymal transition);GO:0016055(Wnt signaling pathway);GO:0021542(dentate gyrus development);GO:0021766(hippocampus development);GO:0021861(forebrain radial glial cell differentiation);GO:0021873(forebrain neuroblast division);GO:0021943(formation of radial glial scaffolds);GO:0022407(regulation of cell-cell adhesion);GO:0030111(regulation of Wnt signaling pathway);GO:0030223(neutrophil differentiation);GO:0030284(estrogen receptor activity);GO:0030307(positive regulation of cell growth);GO:0030326(embryonic limb morphogenesis);GO:0030331(estrogen receptor binding);GO:0030335(positive regulation of cell migration);GO:0030509(BMP signaling pathway);GO:0030854(positive regulation of granulocyte differentiation);GO:0030879(mammary gland development);GO:0032696(negative regulation of interleukin-13 production);GO:0032713(negative regulation of interleukin-4 production);GO:0032714(negative regulation of interleukin-5 production);GO:0032993(protein-DNA complex);GO:0033153(T cell receptor V(D)J recombination);GO:0035326(enhancer binding);GO:0042100(B cell proliferation);GO:0042393(histone binding);GO:0042475(odontogenesis of dentin-containing tooth);GO:0042826(histone deacetylase binding);GO:0043027(cysteine-type endopeptidase inhibitor activity involved in apoptotic process);GO:0043066(negative regulation of apoptotic process);GO:0043154(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process);GO:0043392(negative regulation of DNA binding);GO:0043401(steroid hormone mediated signaling pathway);GO:0043565(sequence-specific DNA binding);GO:0043586(tongue development);GO:0043923(positive regulation by host of viral transcription);GO:0043966(histone H3 acetylation);GO:0043967(histone H4 acetylation);GO:0044212(transcription regulatory region DNA binding);GO:0045063(T-helper 1 cell differentiation);GO:0045295(gamma-catenin binding);GO:0045843(negative regulation of striated muscle tissue development);GO:0045892(negative regulation of transcription, DNA-templated);GO:0045893(positive regulation of transcription, DNA-templated);GO:0045944(positive regulation of transcription by RNA polymerase II);GO:0046632(alpha-beta T cell differentiation);GO:0048069(eye pigmentation);GO:0048341(paraxial mesoderm formation);GO:0048468(cell development);GO:0050909(sensory perception of taste);GO:0060033(anatomical structure regression);GO:0060070(canonical Wnt signaling pathway);GO:0060325(face morphogenesis);GO:0060326(cell chemotaxis);GO:0060561(apoptotic process involved in morphogenesis);GO:0060710(chorio-allantoic fusion);GO:0061153(trachea gland development);GO:0062009(secondary palate development);GO:0070016(armadillo repeat domain binding);GO:0070742(C2H2 zinc finger domain binding);GO:0071345(cellular response to cytokine stimulus);GO:0071353(cellular response to interleukin-4);GO:0071864(positive regulation of cell proliferation in bone marrow);GO:0071866(negative regulation of apoptotic process in bone marrow cell);GO:0071895(odontoblast differentiation);GO:0071899(negative regulation of estrogen receptor binding);GO:1902262(apoptotic process involved in blood vessel morphogenesis);GO:1904837(beta-catenin-TCF complex assembly);GO:1990907(beta-catenin-TCF complex)","04310(Wnt signaling pathway);04390(Hippo signaling pathway);04520(Adherens junction);04916(Melanogenesis);04934(Cushing syndrome);05200(Pathways in cancer);05210(Colorectal cancer);05213(Endometrial cancer);05215(Prostate cancer);05216(Thyroid cancer);05217(Basal cell carcinoma);05221(Acute myeloid leukemia);05224(Breast cancer);05225(Hepatocellular carcinoma);05226(Gastric cancer);05412(Arrhythmogenic right ventricular cardiomyopathy (ARVC))","K04492","NA","lymphoid enhancer binding factor 1 [Source:HGNC Symbol;Acc:HGNC:6551]",0,{"v":0.004207,"d":"0.00"},{"v":0.010579,"d":"0.01"},0,0,0,"inf","inf",1,1,"up","no"]
[60114,0,"chr14","+",100138812,100144232,"ENST00000555606",6,656,"ENSG00000196405","EVL","GO:0003779(actin binding);GO:0005515(protein binding);GO:0005522(profilin binding);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005856(cytoskeleton);GO:0005925(focal adhesion);GO:0007015(actin filament organization);GO:0007166(cell surface receptor signaling pathway);GO:0007399(nervous system development);GO:0007411(axon guidance);GO:0008154(actin polymerization or depolymerization);GO:0009887(animal organ morphogenesis);GO:0010633(negative regulation of epithelial cell migration);GO:0016020(membrane);GO:0017124(SH3 domain binding);GO:0030027(lamellipodium);GO:0030838(positive regulation of actin filament polymerization);GO:0042995(cell projection);GO:0045010(actin nucleation);GO:0045335(phagocytic vesicle);GO:0051289(protein homotetramerization);GO:0051496(positive regulation of stress fiber assembly);GO:0071346(cellular response to interferon-gamma);GO:1900028(negative regulation of ruffle assembly)","NA","NA","NA","Enah/Vasp-like [Source:HGNC Symbol;Acc:HGNC:20234]",{"v":0.163362,"d":"0.16"},{"v":0.106471,"d":"0.11"},0,0,0,{"v":0.259411,"d":"0.26"},{"v":1.04017562863564,"d":"1.04"},{"v":0.0568271410294427,"d":"0.06"},1,1,"up","no"]
[70135,0,"chr16","-",2209654,2210145,"ENST00000566795",2,249,"ENSG00000182685","BRICD5","GO:0005515(protein binding);GO:0005615(extracellular space);GO:0016020(membrane);GO:0016021(integral component of membrane)","NA","NA","NA","BRICHOS domain containing 5 [Source:HGNC Symbol;Acc:HGNC:28309]",{"v":0.123231,"d":"0.12"},{"v":0.038465,"d":"0.04"},{"v":0.117551,"d":"0.12"},{"v":0.136916,"d":"0.14"},{"v":0.000617,"d":"0.00"},{"v":0.14661,"d":"0.15"},{"v":0.982769239432258,"d":"0.98"},{"v":-0.0250753926747131,"d":"-0.03"},1,1,"down","no"]
[93236,0,"chr18","+",12991362,13059314,"ENST00000589596",18,3793,"ENSG00000101639","CEP192","GO:0000086(G2/M transition of mitotic cell cycle);GO:0000242(pericentriolar material);GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0005813(centrosome);GO:0005814(centriole);GO:0005829(cytosol);GO:0005856(cytoskeleton);GO:0009617(response to bacterium);GO:0010389(regulation of G2/M transition of mitotic cell cycle);GO:0010923(negative regulation of phosphatase activity);GO:0019902(phosphatase binding);GO:0051298(centrosome duplication);GO:0071539(protein localization to centrosome);GO:0090222(centrosome-templated microtubule nucleation);GO:0090307(mitotic spindle assembly);GO:0097711(ciliary basal body-plasma membrane docking)","NA","K16725","NA","centrosomal protein 192 [Source:HGNC Symbol;Acc:HGNC:25515]",0,{"v":0.004394,"d":"0.00"},0,0,0,{"v":0.003274,"d":"0.00"},{"v":1.34208918753818,"d":"1.34"},{"v":0.424480547949123,"d":"0.42"},1,1,"up","no"]
[122249,0,"chr2","+",219206815,219208696,"ENST00000409217",7,886,"ENSG00000158552","ZFAND2B","GO:0000502(proteasome complex);GO:0005515(protein binding);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0006616(SRP-dependent cotranslational protein targeting to membrane, translocation);GO:0008270(zinc ion binding);GO:0016020(membrane);GO:0031225(anchored component of membrane);GO:0031593(polyubiquitin modification-dependent protein binding);GO:0036435(K48-linked polyubiquitin modification-dependent protein binding);GO:0043130(ubiquitin binding);GO:0043161(proteasome-mediated ubiquitin-dependent protein catabolic process);GO:0043567(regulation of insulin-like growth factor receptor signaling pathway);GO:0045047(protein targeting to ER);GO:0046872(metal ion binding)","NA","NA","NA","zinc finger AN1-type containing 2B [Source:HGNC Symbol;Acc:HGNC:25206]",{"v":0.30177,"d":"0.30"},{"v":0.063178,"d":"0.06"},{"v":0.100385,"d":"0.10"},{"v":0.227331,"d":"0.23"},{"v":0.129718,"d":"0.13"},{"v":0.244598,"d":"0.24"},{"v":0.773431929353923,"d":"0.77"},{"v":-0.370653770898862,"d":"-0.37"},1,1,"down","no"]
[71889,0,"chr16","+",15687427,15699930,"ENST00000574109",5,843,"ENSG00000072864","NDE1","GO:0000086(G2/M transition of mitotic cell cycle);GO:0000132(establishment of mitotic spindle orientation);GO:0000775(chromosome, centromeric region);GO:0000776(kinetochore);GO:0000777(condensed chromosome kinetochore);GO:0001764(neuron migration);GO:0005515(protein binding);GO:0005694(chromosome);GO:0005737(cytoplasm);GO:0005813(centrosome);GO:0005815(microtubule organizing center);GO:0005819(spindle);GO:0005829(cytosol);GO:0005856(cytoskeleton);GO:0005871(kinesin complex);GO:0005874(microtubule);GO:0007020(microtubule nucleation);GO:0007049(cell cycle);GO:0007059(chromosome segregation);GO:0007100(mitotic centrosome separation);GO:0007275(multicellular organism development);GO:0007399(nervous system development);GO:0007405(neuroblast proliferation);GO:0008017(microtubule binding);GO:0010389(regulation of G2/M transition of mitotic cell cycle);GO:0016020(membrane);GO:0016477(cell migration);GO:0019904(protein domain specific binding);GO:0021987(cerebral cortex development);GO:0030154(cell differentiation);GO:0030900(forebrain development);GO:0031023(microtubule organizing center organization);GO:0031616(spindle pole centrosome);GO:0032154(cleavage furrow);GO:0042802(identical protein binding);GO:0045202(synapse);GO:0047496(vesicle transport along microtubule);GO:0051298(centrosome duplication);GO:0051301(cell division);GO:0051303(establishment of chromosome localization);GO:0051642(centrosome localization);GO:0097711(ciliary basal body-plasma membrane docking);GO:2000574(regulation of microtubule motor activity)","NA","K16738","NA","nudE neurodevelopment protein 1 [Source:HGNC Symbol;Acc:HGNC:17619]",{"v":0.001413,"d":"0.00"},{"v":0.55397,"d":"0.55"},{"v":1.019598,"d":"1.02"},{"v":0.120497,"d":"0.12"},{"v":0.597353,"d":"0.60"},{"v":0.437906,"d":"0.44"},{"v":1.36272794603705,"d":"1.36"},{"v":0.446497572356708,"d":"0.45"},1,1,"up","no"]
[180802,0,"chr7","-",87198228,87219626,"ENST00000474074",2,1031,"ENSG00000135185","TMEM243","GO:0016020(membrane);GO:0016021(integral component of membrane)","NA","NA","NA","transmembrane protein 243 [Source:HGNC Symbol;Acc:HGNC:21707]",{"v":0.099299,"d":"0.10"},{"v":0.096504,"d":"0.10"},{"v":0.181053,"d":"0.18"},{"v":0.030907,"d":"0.03"},{"v":0.170963,"d":"0.17"},{"v":0.036786,"d":"0.04"},{"v":1.57907615982837,"d":"1.58"},{"v":0.659080754958115,"d":"0.66"},1,1,"up","no"]
[100576,0,"chr19","+",17202870,17206133,"ENST00000602158",4,495,"ENSG00000099331","MYO9B","GO:0000146(microfilament motor activity);GO:0000166(nucleotide binding);GO:0003774(motor activity);GO:0003779(actin binding);GO:0005096(GTPase activator activity);GO:0005515(protein binding);GO:0005516(calmodulin binding);GO:0005524(ATP binding);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005856(cytoskeleton);GO:0005884(actin filament);GO:0005938(cell cortex);GO:0007165(signal transduction);GO:0007266(Rho protein signal transduction);GO:0015629(actin cytoskeleton);GO:0016020(membrane);GO:0016459(myosin complex);GO:0016887(ATPase activity);GO:0017048(Rho GTPase binding);GO:0030048(actin filament-based movement);GO:0035023(regulation of Rho protein signal transduction);GO:0035385(Roundabout signaling pathway);GO:0035556(intracellular signal transduction);GO:0043531(ADP binding);GO:0043547(positive regulation of GTPase activity);GO:0046872(metal ion binding);GO:0048471(perinuclear region of cytoplasm);GO:0048495(Roundabout binding);GO:0051056(regulation of small GTPase mediated signal transduction)","NA","K10360","NA","myosin IXB [Source:HGNC Symbol;Acc:HGNC:7609]",0,0,0,0,0,0,1,0,1,1,"no","no"]
[159334,0,"chr5","+",62306452,62385628,"ENST00000407818",21,2315,"ENSG00000068796","KIF2A","GO:0000166(nucleotide binding);GO:0000226(microtubule cytoskeleton organization);GO:0000922(spindle pole);GO:0003774(motor activity);GO:0003777(microtubule motor activity);GO:0005515(protein binding);GO:0005524(ATP binding);GO:0005634(nucleus);GO:0005730(nucleolus);GO:0005737(cytoplasm);GO:0005813(centrosome);GO:0005814(centriole);GO:0005815(microtubule organizing center);GO:0005819(spindle);GO:0005829(cytosol);GO:0005856(cytoskeleton);GO:0005871(kinesin complex);GO:0005874(microtubule);GO:0005876(spindle microtubule);GO:0006890(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum);GO:0007018(microtubule-based movement);GO:0007019(microtubule depolymerization);GO:0007049(cell cycle);GO:0007052(mitotic spindle organization);GO:0007275(multicellular organism development);GO:0007399(nervous system development);GO:0008017(microtubule binding);GO:0016020(membrane);GO:0016604(nuclear body);GO:0016887(ATPase activity);GO:0019886(antigen processing and presentation of exogenous peptide antigen via MHC class II);GO:0030154(cell differentiation);GO:0030334(regulation of cell migration);GO:0051301(cell division);GO:0090307(mitotic spindle assembly);GO:0097228(sperm principal piece);GO:0120103(centriolar subdistal appendage)","NA","K10393","NA","kinesin family member 2A [Source:HGNC Symbol;Acc:HGNC:6318]",0,0,{"v":0.021021,"d":"0.02"},{"v":0.007502,"d":"0.01"},0,{"v":0.007607,"d":"0.01"},{"v":1.39128995962671,"d":"1.39"},{"v":0.476423124208673,"d":"0.48"},1,1,"up","no"]
[12176,0,"chr1","-",155659446,155688774,"ENST00000407221",11,2705,"ENSG00000163374","YY1AP1","GO:0001650(fibrillar center);GO:0003714(transcription corepressor activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005730(nucleolus);GO:0005737(cytoplasm);GO:0008283(cell population proliferation);GO:0030154(cell differentiation);GO:0030183(B cell differentiation);GO:0031011(Ino80 complex);GO:0045892(negative regulation of transcription, DNA-templated);GO:0051726(regulation of cell cycle)","NA","NA","NA","YY1 associated protein 1 [Source:HGNC Symbol;Acc:HGNC:30935]",{"v":0.003743,"d":"0.00"},{"v":0.163882,"d":"0.16"},{"v":0.003226,"d":"0.00"},{"v":0.176149,"d":"0.18"},{"v":0.004902,"d":"0.00"},{"v":0.003659,"d":"0.00"},{"v":0.92496887012073,"d":"0.92"},{"v":-0.11252328242401,"d":"-0.11"},1,1,"down","no"]
[67461,0,"chr15","+",82459472,82470008,"ENST00000456932",7,4817,"ENSG00000276710","CSPG4P10","NA","NA","NA","NA","chondroitin sulfate proteoglycan 4 pseudogene 10 [Source:HGNC Symbol;Acc:HGNC:48361]",{"v":0.124043,"d":"0.12"},{"v":0.089071,"d":"0.09"},{"v":0.222912,"d":"0.22"},{"v":0.101493,"d":"0.10"},{"v":0.141454,"d":"0.14"},{"v":0.15483,"d":"0.15"},{"v":1.09615689192688,"d":"1.10"},{"v":0.132454304690469,"d":"0.13"},1,1,"up","no"]
[5494,0,"chr1","+",44723792,44724378,"ENST00000446792",3,434,"ENSG00000198520","ARMH1","NA","NA","NA","NA","armadillo-like helical domain containing 1 [Source:HGNC Symbol;Acc:HGNC:34345]",0,{"v":0.01393,"d":"0.01"},0,0,0,0,"inf","inf",1,1,"up","no"]
[133308,0,"chr22","+",29307058,29307799,"ENST00000487341",2,550,"ENSG00000185340","GAS2L1","GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0005856(cytoskeleton);GO:0007050(cell cycle arrest);GO:0008017(microtubule binding);GO:0008093(cytoskeletal adaptor activity);GO:0009267(cellular response to starvation);GO:0046966(thyroid hormone receptor binding);GO:0097067(cellular response to thyroid hormone stimulus)","NA","NA","NA","growth arrest specific 2 like 1 [Source:HGNC Symbol;Acc:HGNC:16955]",0,0,{"v":0.16301,"d":"0.16"},0,0,{"v":0.785088,"d":"0.79"},{"v":0.207632774924594,"d":"0.21"},{"v":-2.26789390317103,"d":"-2.27"},1,1,"down","no"]
[55816,0,"chr14","-",34568689,34569129,"ENST00000480487",1,441,"ENSG00000240463","RPS19P3","NA","NA","NA","NA","ribosomal protein S19 pseudogene 3 [Source:HGNC Symbol;Acc:HGNC:23560]",{"v":0.072932,"d":"0.07"},{"v":0.14721,"d":"0.15"},0,{"v":0.068299,"d":"0.07"},0,{"v":0.090208,"d":"0.09"},{"v":1.38884718025071,"d":"1.39"},{"v":0.473887863233149,"d":"0.47"},1,1,"up","no"]
[87645,0,"chr17","+",50426218,50461048,"ENST00000504945",2,544,"ENSG00000167107","ACSF2","GO:0000166(nucleotide binding);GO:0003824(catalytic activity);GO:0003996(acyl-CoA ligase activity);GO:0005515(protein binding);GO:0005524(ATP binding);GO:0005739(mitochondrion);GO:0005759(mitochondrial matrix);GO:0006629(lipid metabolic process);GO:0006631(fatty acid metabolic process);GO:0006637(acyl-CoA metabolic process);GO:0016874(ligase activity)","NA","K00666","EC:6.2.1.-","acyl-CoA synthetase family member 2 [Source:HGNC Symbol;Acc:HGNC:26101]",{"v":0.174026,"d":"0.17"},{"v":0.19938,"d":"0.20"},{"v":0.112557,"d":"0.11"},{"v":0.09595,"d":"0.10"},{"v":0.271081,"d":"0.27"},{"v":0.152727,"d":"0.15"},{"v":0.934979355777112,"d":"0.93"},{"v":-0.096993584054775,"d":"-0.10"},1,1,"down","no"]
[80892,0,"chr17","-",7390448,7394274,"ENST00000571078",4,724,"ENSG00000187838","PLSCR3","GO:0005509(calcium ion binding);GO:0005515(protein binding);GO:0005739(mitochondrion);GO:0005886(plasma membrane);GO:0006915(apoptotic process);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0017121(plasma membrane phospholipid scrambling);GO:0017124(SH3 domain binding);GO:0017128(phospholipid scramblase activity);GO:0031966(mitochondrial membrane);GO:0042593(glucose homeostasis);GO:0042632(cholesterol homeostasis);GO:0048306(calcium-dependent protein binding);GO:0071222(cellular response to lipopolysaccharide)","NA","NA","NA","phospholipid scramblase 3 [Source:HGNC Symbol;Acc:HGNC:16495]",{"v":0.844805,"d":"0.84"},{"v":0.680101,"d":"0.68"},{"v":0.669479,"d":"0.67"},{"v":0.495878,"d":"0.50"},{"v":0.70954,"d":"0.71"},{"v":0.671727,"d":"0.67"},{"v":1.16900132914612,"d":"1.17"},{"v":0.225276570204412,"d":"0.23"},1,1,"up","no"]
[135374,0,"chr22","-",43879678,43892010,"ENST00000597664",9,2537,"ENSG00000100341","PNPLA5","GO:0004806(triglyceride lipase activity);GO:0005737(cytoplasm);GO:0005811(lipid droplet);GO:0005829(cytosol);GO:0006629(lipid metabolic process);GO:0016020(membrane);GO:0016042(lipid catabolic process);GO:0016787(hydrolase activity);GO:0019433(triglyceride catabolic process);GO:0055088(lipid homeostasis)","NA","K16814","EC:3.1.1.-","patatin like phospholipase domain containing 5 [Source:HGNC Symbol;Acc:HGNC:24888]",{"v":0.015991,"d":"0.02"},0,0,0,0,0,"inf","inf",1,1,"up","no"]
[153953,0,"chr4","+",107931585,107936607,"ENST00000513302",2,1562,"ENSG00000155016","CYP2U1","GO:0004497(monooxygenase activity);GO:0005506(iron ion binding);GO:0005737(cytoplasm);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0006082(organic acid metabolic process);GO:0006805(xenobiotic metabolic process);GO:0008395(steroid hydroxylase activity);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016491(oxidoreductase activity);GO:0016705(oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen);GO:0016712(oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen);GO:0020037(heme binding);GO:0031090(organelle membrane);GO:0042738(exogenous drug catabolic process);GO:0043231(intracellular membrane-bounded organelle);GO:0046872(metal ion binding);GO:0055114(oxidation-reduction process);GO:0070330(aromatase activity);GO:0097267(omega-hydroxylase P450 pathway)","00590(Arachidonic acid metabolism)","K07422","NA","cytochrome P450 family 2 subfamily U member 1 [Source:HGNC Symbol;Acc:HGNC:20582]",{"v":0.052024,"d":"0.05"},{"v":0.037758,"d":"0.04"},{"v":0.014074,"d":"0.01"},{"v":0.040379,"d":"0.04"},{"v":0.033212,"d":"0.03"},{"v":0.056273,"d":"0.06"},{"v":0.799728947206308,"d":"0.80"},{"v":-0.322416985865679,"d":"-0.32"},1,1,"down","no"]
[57447,0,"chr14","+",64141438,64226430,"ENST00000555612",36,6766,"ENSG00000054654","SYNE2","GO:0003779(actin binding);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005635(nuclear envelope);GO:0005640(nuclear outer membrane);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0005739(mitochondrion);GO:0005813(centrosome);GO:0005856(cytoskeleton);GO:0005886(plasma membrane);GO:0005925(focal adhesion);GO:0007097(nuclear migration);GO:0010457(centriole-centriole cohesion);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016235(aggresome);GO:0016529(sarcoplasmic reticulum);GO:0021817(nucleokinesis involved in cell motility in cerebral cortex radial glia guided migration);GO:0030016(myofibril);GO:0030018(Z disc);GO:0030054(cell junction);GO:0030335(positive regulation of cell migration);GO:0031022(nuclear migration along microfilament);GO:0031258(lamellipodium membrane);GO:0031527(filopodium membrane);GO:0031965(nuclear membrane);GO:0031981(nuclear lumen);GO:0033017(sarcoplasmic reticulum membrane);GO:0034993(meiotic nuclear membrane microtubule tethering complex);GO:0045111(intermediate filament cytoskeleton);GO:0051015(actin filament binding);GO:0051642(centrosome localization);GO:0070062(extracellular exosome);GO:0090286(cytoskeletal anchoring at nuclear membrane);GO:1902017(regulation of cilium assembly)","NA","K19346","NA","spectrin repeat containing nuclear envelope protein 2 [Source:HGNC Symbol;Acc:HGNC:17084]",{"v":0.007538,"d":"0.01"},0,0,0,0,0,"inf","inf",1,1,"up","no"]
[144489,0,"chr3","+",133806553,133819603,"ENST00000494297",6,555,"ENSG00000144867","SRPRB","GO:0000166(nucleotide binding);GO:0005525(GTP binding);GO:0005737(cytoplasm);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005881(cytoplasmic microtubule);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0036498(IRE1-mediated unfolded protein response)","03060(Protein export)","K12272","NA","SRP receptor subunit beta [Source:HGNC Symbol;Acc:HGNC:24085]",0.09,{"v":0.048034,"d":"0.05"},{"v":0.102937,"d":"0.10"},{"v":0.043012,"d":"0.04"},{"v":0.167772,"d":"0.17"},{"v":0.053886,"d":"0.05"},{"v":0.910458306570446,"d":"0.91"},{"v":-0.135335142793767,"d":"-0.14"},1,1,"down","no"]
[41041,0,"chr12","-",25939329,25959442,"ENST00000545729",4,542,"ENSG00000246695","RASSF8-AS1","NA","NA","NA","NA","RASSF8 antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:48637]",0,{"v":0.208693,"d":"0.21"},{"v":0.087107,"d":"0.09"},0,0,0,"inf","inf",1,1,"up","no"]
[185754,0,"chr7","-",155501298,155644186,"ENST00000637398",8,2744,"ENSG00000283128","AC009403","NA","NA","NA","NA","novel transcript",{"v":0.01976,"d":"0.02"},{"v":0.008019,"d":"0.01"},{"v":0.008012,"d":"0.01"},{"v":0.008668,"d":"0.01"},{"v":0.011956,"d":"0.01"},{"v":0.016988,"d":"0.02"},{"v":0.951584600659364,"d":"0.95"},{"v":-0.071596169837357,"d":"-0.07"},1,1,"down","no"]
[27967,0,"chr11","+",17277023,17301761,"ENST00000533926",5,498,"ENSG00000070081","NUCB2","GO:0003677(DNA binding);GO:0005509(calcium ion binding);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0005615(extracellular space);GO:0005634(nucleus);GO:0005635(nuclear envelope);GO:0005640(nuclear outer membrane);GO:0005737(cytoplasm);GO:0005783(endoplasmic reticulum);GO:0005793(endoplasmic reticulum-Golgi intermediate compartment);GO:0005794(Golgi apparatus);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0016020(membrane);GO:0032099(negative regulation of appetite);GO:0046872(metal ion binding);GO:0070062(extracellular exosome)","NA","K20371","NA","nucleobindin 2 [Source:HGNC Symbol;Acc:HGNC:8044]",{"v":0.39073,"d":"0.39"},{"v":0.44159,"d":"0.44"},{"v":0.483631,"d":"0.48"},{"v":0.552996,"d":"0.55"},{"v":0.687062,"d":"0.69"},{"v":0.760043,"d":"0.76"},{"v":0.657942273915167,"d":"0.66"},{"v":-0.603967083555482,"d":"-0.60"},1,1,"down","no"]
[185766,0,"chr7","+",155672880,155745720,"ENST00000307403",12,4360,"ENSG00000184863","RBM33","GO:0003676(nucleic acid binding);GO:0003723(RNA binding)","NA","NA","NA","RNA binding motif protein 33 [Source:HGNC Symbol;Acc:HGNC:27223]",{"v":0.429078,"d":"0.43"},{"v":0.034604,"d":"0.03"},{"v":0.019856,"d":"0.02"},0,0,0,"inf","inf",1,1,"up","no"]
[82012,0,"chr17","+",16439327,16463986,"ENST00000483588",5,688,"ENSG00000175061","SNHG29","NA","NA","NA","NA","small nucleolar RNA host gene 29 [Source:HGNC Symbol;Acc:HGNC:28619]",{"v":0.335341,"d":"0.34"},{"v":0.087835,"d":"0.09"},{"v":0.026207,"d":"0.03"},{"v":0.289962,"d":"0.29"},{"v":1.368413,"d":"1.37"},{"v":0.413229,"d":"0.41"},{"v":0.216925145925573,"d":"0.22"},{"v":-2.2047307952226,"d":"-2.20"},1,1,"down","no"]
[40141,0,"chr12","-",10631234,10674050,"ENST00000542562",5,582,"ENSG00000060140","STYK1","GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0004713(protein tyrosine kinase activity);GO:0004715(non-membrane spanning protein tyrosine kinase activity);GO:0005515(protein binding);GO:0005524(ATP binding);GO:0005886(plasma membrane);GO:0006468(protein phosphorylation);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0016740(transferase activity);GO:0018108(peptidyl-tyrosine phosphorylation);GO:0031234(extrinsic component of cytoplasmic side of plasma membrane);GO:0042127(regulation of cell population proliferation)","NA","K17510","EC:2.7.10.2","serine/threonine/tyrosine kinase 1 [Source:HGNC Symbol;Acc:HGNC:18889]",0,0,0,0,0,0,1,0,1,1,"no","no"]
[107,0,"chr1","+",778782,782191,"ENST00000457084",2,566,"ENSG00000237491","AL669831","NA","NA","NA","NA","novel transcript",0,0,0,0,0,{"v":0.004915,"d":"0.00"},"-inf","-inf",1,1,"down","no"]
[38724,0,"chr12","+",2877223,2888007,"ENST00000535978",4,543,"ENSG00000171792","RHNO1","GO:0000077(DNA damage checkpoint);GO:0000725(recombinational repair);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005694(chromosome);GO:0006260(DNA replication);GO:0006974(cellular response to DNA damage stimulus);GO:0007049(cell cycle);GO:0034644(cellular response to UV);GO:0070318(positive regulation of G0 to G1 transition);GO:0071479(cellular response to ionizing radiation);GO:1901796(regulation of signal transduction by p53 class mediator)","NA","NA","NA","RAD9-HUS1-RAD1 interacting nuclear orphan 1 [Source:HGNC Symbol;Acc:HGNC:28206]",{"v":0.011792,"d":"0.01"},0,0,{"v":0.011808,"d":"0.01"},0,0,{"v":0.998644986449864,"d":"1.00"},{"v":-0.00195619696532646,"d":"-0.00"},1,1,"down","no"]
[63418,0,"chr15","+",43160394,43185089,"ENST00000563859",5,1540,"ENSG00000137842","TMEM62","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016787(hydrolase activity)","NA","NA","NA","transmembrane protein 62 [Source:HGNC Symbol;Acc:HGNC:26269]",{"v":0.078617,"d":"0.08"},{"v":0.521263,"d":"0.52"},{"v":0.022508,"d":"0.02"},{"v":0.236282,"d":"0.24"},{"v":0.081813,"d":"0.08"},{"v":0.129883,"d":"0.13"},{"v":1.38932715445848,"d":"1.39"},{"v":0.474386360687059,"d":"0.47"},1,1,"up","no"]
[63272,0,"chr15","+",42276272,42281112,"ENST00000568687",3,444,"ENSG00000214013","GANC","GO:0000023(maltose metabolic process);GO:0003824(catalytic activity);GO:0004553(hydrolase activity, hydrolyzing O-glycosyl compounds);GO:0004558(alpha-1,4-glucosidase activity);GO:0005975(carbohydrate metabolic process);GO:0008152(metabolic process);GO:0016787(hydrolase activity);GO:0016798(hydrolase activity, acting on glycosyl bonds);GO:0030246(carbohydrate binding);GO:0032450(maltose alpha-glucosidase activity);GO:0090599(alpha-glucosidase activity)","00052(Galactose metabolism);00500(Starch and sucrose metabolism)","NA","NA","glucosidase alpha, neutral C [Source:HGNC Symbol;Acc:HGNC:4139]",{"v":0.021498,"d":"0.02"},{"v":0.020137,"d":"0.02"},{"v":0.027114,"d":"0.03"},{"v":0.011122,"d":"0.01"},{"v":0.0043,"d":"0.00"},{"v":0.018738,"d":"0.02"},{"v":2.01255854800937,"d":"2.01"},{"v":1.0090307537585,"d":"1.01"},1,1,"up","no"]
[46116,0,"chr12","+",80402178,80409550,"ENST00000623635",6,1078,"ENSG00000139304","PTPRQ","GO:0002244(hematopoietic progenitor cell differentiation);GO:0004721(phosphoprotein phosphatase activity);GO:0004725(protein tyrosine phosphatase activity);GO:0005515(protein binding);GO:0006470(protein dephosphorylation);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016311(dephosphorylation);GO:0016787(hydrolase activity);GO:0016791(phosphatase activity);GO:0032421(stereocilium bundle);GO:0035335(peptidyl-tyrosine dephosphorylation);GO:0042472(inner ear morphogenesis);GO:0050885(neuromuscular process controlling balance);GO:0050910(detection of mechanical stimulus involved in sensory perception of sound);GO:0060116(vestibular receptor cell morphogenesis)","NA","K16910","EC:3.1.3.48","protein tyrosine phosphatase, receptor type Q [Source:HGNC Symbol;Acc:HGNC:9679]",0,0,0,0,0,0,1,0,1,1,"no","no"]
[155279,0,"chr4","-",145064572,145097382,"ENST00000504721",4,477,"ENSG00000164162","ANAPC10","GO:0005654(nucleoplasm);GO:0005680(anaphase-promoting complex);GO:0005829(cytosol);GO:0006511(ubiquitin-dependent protein catabolic process);GO:0007049(cell cycle);GO:0016567(protein ubiquitination);GO:0031145(anaphase-promoting complex-dependent catabolic process);GO:0051301(cell division);GO:0070979(protein K11-linked ubiquitination);GO:1901990(regulation of mitotic cell cycle phase transition)","04110(Cell cycle);04114(Oocyte meiosis);04120(Ubiquitin mediated proteolysis);04914(Progesterone-mediated oocyte maturation);05166(Human T-cell leukemia virus 1 infection)","K03357","NA","anaphase promoting complex subunit 10 [Source:HGNC Symbol;Acc:HGNC:24077]",0,0,{"v":0.244694,"d":"0.24"},0,0,0,"inf","inf",1,1,"up","no"]
[147858,0,"chr3","-",187698259,187702557,"ENST00000358241",2,1346,"ENSG00000198471","RTP2","GO:0001580(detection of chemical stimulus involved in sensory perception of bitter taste);GO:0005515(protein binding);GO:0005886(plasma membrane);GO:0006612(protein targeting to membrane);GO:0009986(cell surface);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0031849(olfactory receptor binding);GO:0051205(protein insertion into membrane)","NA","NA","NA","receptor transporter protein 2 [Source:HGNC Symbol;Acc:HGNC:32486]",0,0,0,{"v":0.03124,"d":"0.03"},0,0,"-inf","-inf",1,1,"down","no"]
[56373,0,"chr14","+",49677369,49677893,"ENST00000554632",1,525,"ENSG00000259155","AL591767","NA","NA","NA","NA","serine/threonine kinase 16 (STK16) pseudogene",0,0,{"v":0.063257,"d":"0.06"},0,0,0,"inf","inf",1,1,"up","no"]
[155654,0,"chr4","+",153344681,153414865,"ENST00000509752",10,844,"ENSG00000121211","MND1","GO:0003677(DNA binding);GO:0003690(double-stranded DNA binding);GO:0005634(nucleus);GO:0006310(DNA recombination);GO:0007131(reciprocal meiotic recombination);GO:0051321(meiotic cell cycle)","NA","NA","NA","meiotic nuclear divisions 1 [Source:HGNC Symbol;Acc:HGNC:24839]",0,0,0,0,0,{"v":0.022729,"d":"0.02"},"-inf","-inf",1,1,"down","no"]
[173754,0,"chr6","-",127289267,127343549,"ENST00000528402",4,1449,"ENSG00000093144","ECHDC1","GO:0003824(catalytic activity);GO:0004300(enoyl-CoA hydratase activity);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0006635(fatty acid beta-oxidation);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016829(lyase activity);GO:0016831(carboxy-lyase activity)","00640(Propanoate metabolism)","K18426","4.1.1.-;EC:4.1.1.94","ethylmalonyl-CoA decarboxylase 1 [Source:HGNC Symbol;Acc:HGNC:21489]",{"v":0.299461,"d":"0.30"},0,0,{"v":0.460485,"d":"0.46"},{"v":0.242821,"d":"0.24"},{"v":0.214565,"d":"0.21"},{"v":0.326256086094887,"d":"0.33"},{"v":-1.61592328041705,"d":"-1.62"},1,1,"down","no"]
[203473,0,"chrX","-",53221705,53225198,"ENST00000349663",2,548,"ENSG00000126012","KDM5C","GO:0000981(DNA-binding transcription factor activity, RNA polymerase II-specific);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0006325(chromatin organization);GO:0006338(chromatin remodeling);GO:0006357(regulation of transcription by RNA polymerase II);GO:0008270(zinc ion binding);GO:0016491(oxidoreductase activity);GO:0032452(histone demethylase activity);GO:0032453(histone demethylase activity (H3-K4 specific));GO:0034647(histone demethylase activity (H3-trimethyl-K4 specific));GO:0034720(histone H3-K4 demethylation);GO:0034721(histone H3-K4 demethylation, trimethyl-H3-K4-specific);GO:0035097(histone methyltransferase complex);GO:0045892(negative regulation of transcription, DNA-templated);GO:0046872(metal ion binding);GO:0048511(rhythmic process);GO:0051213(dioxygenase activity);GO:0055114(oxidation-reduction process)","NA","K11446","EC:1.14.11.-","lysine demethylase 5C [Source:HGNC Symbol;Acc:HGNC:11114]",{"v":0.599435,"d":"0.60"},{"v":0.388032,"d":"0.39"},{"v":0.509952,"d":"0.51"},{"v":0.396083,"d":"0.40"},{"v":0.304156,"d":"0.30"},{"v":0.352167,"d":"0.35"},{"v":1.42285296739091,"d":"1.42"},{"v":0.508786586547716,"d":"0.51"},1,1,"up","no"]
[97195,0,"chr19","-",3544676,3547331,"ENST00000589063",4,590,"ENSG00000161091","MFSD12","GO:0005215(transporter activity);GO:0005765(lysosomal membrane);GO:0005887(integral component of plasma membrane);GO:0008643(carbohydrate transport);GO:0015293(symporter activity);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0055085(transmembrane transport);GO:0071702(organic substance transport)","NA","NA","NA","major facilitator superfamily domain containing 12 [Source:HGNC Symbol;Acc:HGNC:28299]",{"v":0.115261,"d":"0.12"},{"v":0.137278,"d":"0.14"},{"v":0.122656,"d":"0.12"},{"v":0.158953,"d":"0.16"},{"v":0.231702,"d":"0.23"},{"v":0.084684,"d":"0.08"},{"v":0.789320884673886,"d":"0.79"},{"v":-0.341316172829725,"d":"-0.34"},1,1,"down","no"]
[2285,0,"chr1","-",19304166,19311907,"ENST00000489286",5,725,"ENSG00000053371","AKR7A2","GO:0004032(alditol:NADP+ 1-oxidoreductase activity);GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0005794(Golgi apparatus);GO:0005829(cytosol);GO:0005975(carbohydrate metabolic process);GO:0006081(cellular aldehyde metabolic process);GO:0006805(xenobiotic metabolic process);GO:0009055(electron transfer activity);GO:0016491(oxidoreductase activity);GO:0019119(phenanthrene-9,10-epoxide hydrolase activity);GO:0022900(electron transport chain);GO:0044597(daunorubicin metabolic process);GO:0044598(doxorubicin metabolic process);GO:0055114(oxidation-reduction process);GO:0070062(extracellular exosome)","00980(Metabolism of xenobiotics by cytochrome P450)","K15303","NA","aldo-keto reductase family 7 member A2 [Source:HGNC Symbol;Acc:HGNC:389]",0,0,0,0,0,0,1,0,1,1,"no","no"]
[118208,0,"chr2","-",151882993,151884166,"ENST00000475848",1,1174,"ENSG00000182389","CACNB4","GO:0005244(voltage-gated ion channel activity);GO:0005245(voltage-gated calcium channel activity);GO:0005262(calcium channel activity);GO:0005515(protein binding);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0005891(voltage-gated calcium channel complex);GO:0006811(ion transport);GO:0006816(calcium ion transport);GO:0007268(chemical synaptic transmission);GO:0007528(neuromuscular junction development);GO:0008331(high voltage-gated calcium channel activity);GO:0009898(cytoplasmic side of plasma membrane);GO:0034765(regulation of ion transmembrane transport);GO:0051899(membrane depolarization);GO:0061337(cardiac conduction);GO:0070588(calcium ion transmembrane transport);GO:1901385(regulation of voltage-gated calcium channel activity)","04010(MAPK signaling pathway);04260(Cardiac muscle contraction);04261(Adrenergic signaling in cardiomyocytes);04921(Oxytocin signaling pathway);05410(Hypertrophic cardiomyopathy (HCM));05412(Arrhythmogenic right ventricular cardiomyopathy (ARVC));05414(Dilated cardiomyopathy (DCM))","NA","NA","calcium voltage-gated channel auxiliary subunit beta 4 [Source:HGNC Symbol;Acc:HGNC:1404]",{"v":0.006215,"d":"0.01"},0,0,{"v":0.004826,"d":"0.00"},0,{"v":0.008259,"d":"0.01"},{"v":0.474971341230416,"d":"0.47"},{"v":-1.07408762799555,"d":"-1.07"},1,1,"down","no"]
[157568,0,"chr5","+",10250319,10254584,"ENST00000510326",2,567,"ENSG00000150753","CCT5","GO:0000166(nucleotide binding);GO:0003730(mRNA 3'-UTR binding);GO:0005515(protein binding);GO:0005524(ATP binding);GO:0005730(nucleolus);GO:0005737(cytoplasm);GO:0005813(centrosome);GO:0005815(microtubule organizing center);GO:0005829(cytosol);GO:0005832(chaperonin-containing T-complex);GO:0005856(cytoskeleton);GO:0005874(microtubule);GO:0006457(protein folding);GO:0007339(binding of sperm to zona pellucida);GO:0009615(response to virus);GO:0031681(G-protein beta-subunit binding);GO:0032212(positive regulation of telomere maintenance via telomerase);GO:0044297(cell body);GO:0048027(mRNA 5'-UTR binding);GO:0048487(beta-tubulin binding);GO:0050821(protein stabilization);GO:0051082(unfolded protein binding);GO:0070062(extracellular exosome);GO:1901998(toxin transport);GO:1904851(positive regulation of establishment of protein localization to telomere);GO:1904871(positive regulation of protein localization to Cajal body);GO:1904874(positive regulation of telomerase RNA localization to Cajal body)","NA","K09497","NA","chaperonin containing TCP1 subunit 5 [Source:HGNC Symbol;Acc:HGNC:1618]",{"v":5.472547,"d":"5.47"},{"v":0.238906,"d":"0.24"},{"v":0.226491,"d":"0.23"},{"v":0.053369,"d":"0.05"},{"v":0.403661,"d":"0.40"},{"v":0.271588,"d":"0.27"},{"v":8.1495982805805,"d":"8.15"},{"v":3.02672894610467,"d":"3.03"},1,1,"up","no"]
[140272,0,"chr3","+",50273157,50277546,"ENST00000456210",8,2065,"ENSG00000012171","SEMA3B","GO:0001755(neural crest cell migration);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0005615(extracellular space);GO:0005783(endoplasmic reticulum);GO:0005887(integral component of plasma membrane);GO:0007267(cell-cell signaling);GO:0007411(axon guidance);GO:0030215(semaphorin receptor binding);GO:0030335(positive regulation of cell migration);GO:0038191(neuropilin binding);GO:0045499(chemorepellent activity);GO:0048843(negative regulation of axon extension involved in axon guidance);GO:0050919(negative chemotaxis);GO:0061643(chemorepulsion of axon);GO:0062023(collagen-containing extracellular matrix);GO:0071526(semaphorin-plexin signaling pathway)","04360(Axon guidance)","K06840","NA","semaphorin 3B [Source:HGNC Symbol;Acc:HGNC:10724]",0,{"v":0.021555,"d":"0.02"},0,{"v":0.015432,"d":"0.02"},0,{"v":0.016502,"d":"0.02"},{"v":0.67498590843615,"d":"0.67"},{"v":-0.567070711303886,"d":"-0.57"},1,1,"down","no"]
[197603,0,"chr9","-",95185190,95254364,"ENST00000649519",6,2114,"ENSG00000158169","FANCC","GO:0002262(myeloid cell homeostasis);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0006281(DNA repair);GO:0006289(nucleotide-excision repair);GO:0006974(cellular response to DNA damage stimulus);GO:0007276(gamete generation);GO:0007281(germ cell development);GO:0019430(removal of superoxide radicals);GO:0034599(cellular response to oxidative stress);GO:0036297(interstrand cross-link repair);GO:0043240(Fanconi anaemia nuclear complex);GO:0048854(brain morphogenesis);GO:0065003(protein-containing complex assembly);GO:0097150(neuronal stem cell population maintenance)","03460(Fanconi anemia pathway)","K10890","NA","FA complementation group C [Source:HGNC Symbol;Acc:HGNC:3584]",0,0,0,0,0,0,1,0,1,1,"no","no"]
[14613,0,"chr1","+",183128596,183133538,"ENST00000478064",5,782,"ENSG00000135862","LAMC1","GO:0005201(extracellular matrix structural constituent);GO:0005576(extracellular region);GO:0005604(basement membrane);GO:0005606(laminin-1 complex);GO:0005615(extracellular space);GO:0005788(endoplasmic reticulum lumen);GO:0007155(cell adhesion);GO:0007492(endoderm development);GO:0016477(cell migration);GO:0022617(extracellular matrix disassembly);GO:0030023(extracellular matrix constituent conferring elasticity);GO:0030198(extracellular matrix organization);GO:0031012(extracellular matrix);GO:0031581(hemidesmosome assembly);GO:0034446(substrate adhesion-dependent cell spreading);GO:0043259(laminin-10 complex);GO:0043260(laminin-11 complex);GO:0043687(post-translational protein modification);GO:0044267(cellular protein metabolic process);GO:0050679(positive regulation of epithelial cell proliferation);GO:0062023(collagen-containing extracellular matrix);GO:0065003(protein-containing complex assembly);GO:0070062(extracellular exosome)","04151(PI3K-Akt signaling pathway);04510(Focal adhesion);04512(ECM-receptor interaction);05020(Prion diseases);05145(Toxoplasmosis);05146(Amoebiasis);05165(Human papillomavirus infection);05200(Pathways in cancer);05222(Small cell lung cancer)","K05635","NA","laminin subunit gamma 1 [Source:HGNC Symbol;Acc:HGNC:6492]",0,0,0,0,0,0,1,0,1,1,"no","no"]
[154137,0,"chr4","+",110549428,110553517,"ENST00000502711",3,579,"ENSG00000138792","ENPEP","GO:0001525(angiogenesis);GO:0002003(angiotensin maturation);GO:0003081(regulation of systemic arterial blood pressure by renin-angiotensin);GO:0004177(aminopeptidase activity);GO:0005737(cytoplasm);GO:0005765(lysosomal membrane);GO:0005886(plasma membrane);GO:0005887(integral component of plasma membrane);GO:0005903(brush border);GO:0006508(proteolysis);GO:0007267(cell-cell signaling);GO:0008233(peptidase activity);GO:0008237(metallopeptidase activity);GO:0008270(zinc ion binding);GO:0008283(cell population proliferation);GO:0009897(external side of plasma membrane);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016324(apical plasma membrane);GO:0016477(cell migration);GO:0016787(hydrolase activity);GO:0031410(cytoplasmic vesicle);GO:0032835(glomerulus development);GO:0042277(peptide binding);GO:0043171(peptide catabolic process);GO:0045177(apical part of cell);GO:0046872(metal ion binding);GO:0070006(metalloaminopeptidase activity);GO:0070062(extracellular exosome)","04614(Renin-angiotensin system)","K11141","EC:3.4.11.7","glutamyl aminopeptidase [Source:HGNC Symbol;Acc:HGNC:3355]",{"v":0.002961,"d":"0.00"},{"v":0.005427,"d":"0.01"},{"v":0.000595,"d":"0.00"},{"v":0.000946,"d":"0.00"},{"v":0.157273,"d":"0.16"},{"v":0.005685,"d":"0.01"},{"v":0.0548064720812183,"d":"0.05"},{"v":-4.18950991906812,"d":"-4.19"},1,1,"down","no"]
[167198,0,"chr6","+",8435627,8785442,"ENST00000644610",6,1274,"ENSG00000285219","AL591485","NA","NA","NA","NA","highly up-regulated in liver cancer (non-protein coding)",0,0,0,0,0,0,1,0,1,1,"no","no"]
[190676,0,"chr8","-",86478825,86486499,"ENST00000519145",3,258,"ENSG00000176623","RMDN1","GO:0000922(spindle pole);GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0005819(spindle);GO:0005856(cytoskeleton);GO:0005874(microtubule)","NA","NA","NA","regulator of microtubule dynamics 1 [Source:HGNC Symbol;Acc:HGNC:24285]",{"v":0.000278,"d":"0.00"},{"v":0.107438,"d":"0.11"},{"v":0.183489,"d":"0.18"},{"v":0.273762,"d":"0.27"},{"v":0.227119,"d":"0.23"},{"v":0.099139,"d":"0.10"},{"v":0.485325489150362,"d":"0.49"},{"v":-1.04297546288096,"d":"-1.04"},1,1,"down","no"]
[13862,0,"chr1","-",169690665,169711702,"ENST00000650983",9,2442,"ENSG00000188404","SELL","GO:0002020(protease binding);GO:0005509(calcium ion binding);GO:0005515(protein binding);GO:0005886(plasma membrane);GO:0005887(integral component of plasma membrane);GO:0007155(cell adhesion);GO:0008201(heparin binding);GO:0009897(external side of plasma membrane);GO:0009986(cell surface);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016339(calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules);GO:0030246(carbohydrate binding);GO:0030667(secretory granule membrane);GO:0033198(response to ATP);GO:0043208(glycosphingolipid binding);GO:0043312(neutrophil degranulation);GO:0046872(metal ion binding);GO:0050776(regulation of immune response);GO:0050839(cell adhesion molecule binding);GO:0050900(leukocyte migration);GO:0050901(leukocyte tethering or rolling);GO:0070492(oligosaccharide binding)","04514(Cell adhesion molecules (CAMs))","K06495","NA","selectin L [Source:HGNC Symbol;Acc:HGNC:10720]",{"v":0.017195,"d":"0.02"},{"v":0.090107,"d":"0.09"},{"v":0.018005,"d":"0.02"},{"v":0.034438,"d":"0.03"},0,0,{"v":3.63862593646553,"d":"3.64"},{"v":1.86339374468201,"d":"1.86"},1,1,"up","no"]
[44779,0,"chr12","-",57534382,57535546,"ENST00000551142",2,562,"ENSG00000175203","DCTN2","GO:0000086(G2/M transition of mitotic cell cycle);GO:0000278(mitotic cell cycle);GO:0000776(kinetochore);GO:0003774(motor activity);GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0005813(centrosome);GO:0005815(microtubule organizing center);GO:0005829(cytosol);GO:0005856(cytoskeleton);GO:0005869(dynactin complex);GO:0005874(microtubule);GO:0006888(endoplasmic reticulum to Golgi vesicle-mediated transport);GO:0007017(microtubule-based process);GO:0007052(mitotic spindle organization);GO:0008283(cell population proliferation);GO:0010389(regulation of G2/M transition of mitotic cell cycle);GO:0016020(membrane);GO:0019886(antigen processing and presentation of exogenous peptide antigen via MHC class II);GO:0019901(protein kinase binding);GO:0030286(dynein complex);GO:0030426(growth cone);GO:0030507(spectrin binding);GO:0031982(vesicle);GO:0032402(melanosome transport);GO:0042802(identical protein binding);GO:0070062(extracellular exosome);GO:0071539(protein localization to centrosome);GO:0097711(ciliary basal body-plasma membrane docking)","04962(Vasopressin-regulated water reabsorption);05016(Huntington disease)","K10424","NA","dynactin subunit 2 [Source:HGNC Symbol;Acc:HGNC:2712]",{"v":0.35635,"d":"0.36"},{"v":0.164939,"d":"0.16"},{"v":0.259934,"d":"0.26"},{"v":0.262131,"d":"0.26"},{"v":0.320293,"d":"0.32"},{"v":0.061202,"d":"0.06"},{"v":1.21378409200374,"d":"1.21"},{"v":0.279511817723969,"d":"0.28"},1,1,"up","no"]
[8012,0,"chr1","-",86868096,86914065,"ENST00000467557",4,499,"ENSG00000183291","SELENOF","GO:0005515(protein binding);GO:0005783(endoplasmic reticulum);GO:0005788(endoplasmic reticulum lumen);GO:0051084('de novo' posttranslational protein folding)","NA","NA","NA","selenoprotein F [Source:HGNC Symbol;Acc:HGNC:17705]",{"v":0.074708,"d":"0.07"},0,{"v":0.269912,"d":"0.27"},0,{"v":0.087701,"d":"0.09"},{"v":0.148325,"d":"0.15"},{"v":1.46009337954293,"d":"1.46"},{"v":0.54606063889673,"d":"0.55"},1,1,"up","no"]
[53102,0,"chr13","-",100663120,100674795,"ENST00000440120",5,584,"ENSG00000125247","TMTC4","GO:0000030(mannosyltransferase activity);GO:0004169(dolichyl-phosphate-mannose-protein mannosyltransferase activity);GO:0005515(protein binding);GO:0005783(endoplasmic reticulum);GO:0006486(protein glycosylation);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016740(transferase activity);GO:0035269(protein O-linked mannosylation)","NA","NA","NA","transmembrane and tetratricopeptide repeat containing 4 [Source:HGNC Symbol;Acc:HGNC:25904]",0,0,0,0,{"v":0.034707,"d":"0.03"},0,"-inf","-inf",1,1,"down","no"]
[14326,0,"chr1","-",178724306,178726285,"ENST00000608517",1,1980,"ENSG00000273062","AL449106","NA","NA","NA","NA","novel transcript, antisense to RALGPS2",{"v":0.031961,"d":"0.03"},0,0,{"v":0.021237,"d":"0.02"},{"v":0.101642,"d":"0.10"},{"v":0.008418,"d":"0.01"},{"v":0.243425211543295,"d":"0.24"},{"v":-2.03844949920685,"d":"-2.04"},1,1,"down","no"]
[5221,0,"chr1","+",43707527,43930891,"ENST00000372372",12,2109,"ENSG00000126091","ST3GAL3","GO:0000139(Golgi membrane);GO:0003836(beta-galactoside (CMP) alpha-2,3-sialyltransferase activity);GO:0005576(extracellular region);GO:0005794(Golgi apparatus);GO:0006486(protein glycosylation);GO:0008118(N-acetyllactosaminide alpha-2,3-sialyltransferase activity);GO:0008373(sialyltransferase activity);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016266(O-glycan processing);GO:0016740(transferase activity);GO:0016757(transferase activity, transferring glycosyl groups);GO:0018146(keratan sulfate biosynthetic process);GO:0032580(Golgi cisterna membrane);GO:0097503(sialylation)","00514(Other types of O-glycan biosynthesis);00515(Mannose type O-glycan biosynthesis);00533(Glycosaminoglycan biosynthesis - keratan sulfate);00601(Glycosphingolipid biosynthesis - lacto and neolacto series)","K00781","EC:2.4.99.6","ST3 beta-galactoside alpha-2,3-sialyltransferase 3 [Source:HGNC Symbol;Acc:HGNC:10866]",0,{"v":0.001447,"d":"0.00"},0,0,0,{"v":0.001939,"d":"0.00"},{"v":0.746260959257349,"d":"0.75"},{"v":-0.422247881575068,"d":"-0.42"},1,1,"down","no"]
[169297,0,"chr6","+",31927763,31945624,"ENST00000383177",14,1847,"ENSG00000166278","C2","GO:0002376(immune system process);GO:0004252(serine-type endopeptidase activity);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0005615(extracellular space);GO:0006508(proteolysis);GO:0006956(complement activation);GO:0006958(complement activation, classical pathway);GO:0007584(response to nutrient);GO:0008233(peptidase activity);GO:0008236(serine-type peptidase activity);GO:0016787(hydrolase activity);GO:0030449(regulation of complement activation);GO:0045087(innate immune response);GO:0046872(metal ion binding);GO:0070062(extracellular exosome);GO:2000427(positive regulation of apoptotic cell clearance)","04610(Complement and coagulation cascades);05133(Pertussis);05150(Staphylococcus aureus infection);05322(Systemic lupus erythematosus)","NA","NA","complement C2 [Source:HGNC Symbol;Acc:HGNC:1248]",0,0,{"v":0.185755,"d":"0.19"},0,0,0,"inf","inf",1,1,"up","no"]
[21398,0,"chr10","-",63192939,63193649,"ENST00000490669",2,518,"ENSG00000171988","JMJD1C","GO:0000785(chromatin);GO:0000976(transcription regulatory region sequence-specific DNA binding);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0006325(chromatin organization);GO:0006355(regulation of transcription, DNA-templated);GO:0007596(blood coagulation);GO:0016491(oxidoreductase activity);GO:0031490(chromatin DNA binding);GO:0032454(histone demethylase activity (H3-K9 specific));GO:0033169(histone H3-K9 demethylation);GO:0046872(metal ion binding);GO:0046966(thyroid hormone receptor binding);GO:0051213(dioxygenase activity);GO:0055114(oxidation-reduction process)","05202(Transcriptional misregulation in cancer)","K11449","EC:1.14.11.-","jumonji domain containing 1C [Source:HGNC Symbol;Acc:HGNC:12313]",{"v":0.104981,"d":"0.10"},{"v":0.091298,"d":"0.09"},{"v":0.173116,"d":"0.17"},{"v":0.124263,"d":"0.12"},{"v":0.004278,"d":"0.00"},{"v":0.003249,"d":"0.00"},{"v":2.80290613855376,"d":"2.80"},{"v":1.4869234333785,"d":"1.49"},1,1,"up","no"]
[19450,0,"chr10","-",15796120,15838279,"ENST00000436829",8,618,"ENSG00000148481","MINDY3","GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0006508(proteolysis);GO:0006915(apoptotic process);GO:0008233(peptidase activity);GO:0008234(cysteine-type peptidase activity);GO:0016787(hydrolase activity);GO:0016807(cysteine-type carboxypeptidase activity);GO:0031965(nuclear membrane);GO:0036459(thiol-dependent ubiquitinyl hydrolase activity);GO:0071108(protein K48-linked deubiquitination);GO:1990380(Lys48-specific deubiquitinase activity)","NA","K22647","EC:3.4.19.12","MINDY lysine 48 deubiquitinase 3 [Source:HGNC Symbol;Acc:HGNC:23578]",{"v":0.179551,"d":"0.18"},{"v":0.24185,"d":"0.24"},{"v":0.252102,"d":"0.25"},{"v":0.188568,"d":"0.19"},{"v":0.071718,"d":"0.07"},{"v":0.391976,"d":"0.39"},{"v":1.03256513486912,"d":"1.03"},{"v":0.0462327906411038,"d":"0.05"},1,1,"up","no"]
[126308,0,"chr20","-",35303971,35315436,"ENST00000473982",4,551,"ENSG00000101019","UQCC1","GO:0005515(protein binding);GO:0005739(mitochondrion);GO:0005743(mitochondrial inner membrane);GO:0016020(membrane);GO:0031410(cytoplasmic vesicle);GO:0034551(mitochondrial respiratory chain complex III assembly);GO:0070131(positive regulation of mitochondrial translation)","NA","K17662","NA","ubiquinol-cytochrome c reductase complex assembly factor 1 [Source:HGNC Symbol;Acc:HGNC:15891]",{"v":0.301315,"d":"0.30"},{"v":0.050897,"d":"0.05"},{"v":0.039899,"d":"0.04"},0,0,0,"inf","inf",1,1,"up","no"]
[45976,0,"chr12","+",76619386,76620043,"ENST00000603536",1,658,"ENSG00000271142","YWHAQP7","NA","NA","NA","NA","YWHAQ pseudogene 7 [Source:HGNC Symbol;Acc:HGNC:37686]",0,0,0,{"v":0.031952,"d":"0.03"},0,0,"-inf","-inf",1,1,"down","no"]
[11070,0,"chr1","+",151038840,151046687,"ENST00000485855",8,982,"ENSG00000163141","BNIPL","GO:0004309(exopolyphosphatase activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0006798(polyphosphate catabolic process);GO:0006915(apoptotic process);GO:0008285(negative regulation of cell population proliferation);GO:0040009(regulation of growth rate);GO:0042802(identical protein binding)","NA","K18448","NA","BCL2 interacting protein like [Source:HGNC Symbol;Acc:HGNC:16976]",0,0,0,0,{"v":0.032096,"d":"0.03"},0,"-inf","-inf",1,1,"down","no"]
[110836,0,"chr2","-",27364358,27365082,"ENST00000478311",2,607,"ENSG00000115211","EIF2B4","GO:0001541(ovarian follicle development);GO:0003743(translation initiation factor activity);GO:0005085(guanyl-nucleotide exchange factor activity);GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005851(eukaryotic translation initiation factor 2B complex);GO:0006412(translation);GO:0006413(translational initiation);GO:0006417(regulation of translation);GO:0009408(response to heat);GO:0009749(response to glucose);GO:0014003(oligodendrocyte development);GO:0031369(translation initiation factor binding);GO:0042552(myelination);GO:0043434(response to peptide hormone);GO:0044237(cellular metabolic process);GO:0050852(T cell receptor signaling pathway)","03013(RNA transport);05168(Herpes simplex virus 1 infection)","K03680","NA","eukaryotic translation initiation factor 2B subunit delta [Source:HGNC Symbol;Acc:HGNC:3260]",{"v":0.00047,"d":"0.00"},{"v":0.046872,"d":"0.05"},{"v":0.161287,"d":"0.16"},{"v":0.060594,"d":"0.06"},{"v":0.000666,"d":"0.00"},{"v":0.167383,"d":"0.17"},{"v":0.912466159033952,"d":"0.91"},{"v":-0.132157040773622,"d":"-0.13"},1,1,"down","no"]
[116338,0,"chr2","-",111867998,111880878,"ENST00000451367",5,662,"ENSG00000153107","ANAPC1","GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005680(anaphase-promoting complex);GO:0005829(cytosol);GO:0006511(ubiquitin-dependent protein catabolic process);GO:0007049(cell cycle);GO:0007091(metaphase/anaphase transition of mitotic cell cycle);GO:0016567(protein ubiquitination);GO:0031145(anaphase-promoting complex-dependent catabolic process);GO:0051301(cell division);GO:0061630(ubiquitin protein ligase activity);GO:0070979(protein K11-linked ubiquitination);GO:1901990(regulation of mitotic cell cycle phase transition)","04110(Cell cycle);04114(Oocyte meiosis);04120(Ubiquitin mediated proteolysis);04914(Progesterone-mediated oocyte maturation);05166(Human T-cell leukemia virus 1 infection)","K03348","NA","anaphase promoting complex subunit 1 [Source:HGNC Symbol;Acc:HGNC:19988]",0,0,{"v":0.027018,"d":"0.03"},0,0,{"v":0.020084,"d":"0.02"},{"v":1.34524995020912,"d":"1.35"},{"v":0.427874253395136,"d":"0.43"},1,1,"up","no"]
[136218,0,"chr3","-",3156090,3174121,"ENST00000480249",4,565,"ENSG00000113851","CRBN","GO:0005515(protein binding);GO:0005634(nucleus);GO:0005730(nucleolus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0016567(protein ubiquitination);GO:0031464(Cul4A-RING E3 ubiquitin ligase complex);GO:0032463(negative regulation of protein homooligomerization);GO:0034766(negative regulation of ion transmembrane transport);GO:0043161(proteasome-mediated ubiquitin-dependent protein catabolic process);GO:0046872(metal ion binding);GO:0090073(positive regulation of protein homodimerization activity)","NA","K11793","NA","cereblon [Source:HGNC Symbol;Acc:HGNC:30185]",{"v":0.017241,"d":"0.02"},{"v":0.015023,"d":"0.02"},{"v":0.006292,"d":"0.01"},{"v":0.016322,"d":"0.02"},{"v":0.01973,"d":"0.02"},{"v":0.017495,"d":"0.02"},{"v":0.720040338394308,"d":"0.72"},{"v":-0.473850362816781,"d":"-0.47"},1,1,"down","no"]
[134396,0,"chr22","+",37614133,37621632,"ENST00000423024",6,559,"ENSG00000100083","GGA1","GO:0003674(molecular_function);GO:0005515(protein binding);GO:0005622(intracellular);GO:0005623(cell);GO:0005654(nucleoplasm);GO:0005768(endosome);GO:0005769(early endosome);GO:0005794(Golgi apparatus);GO:0005829(cytosol);GO:0006886(intracellular protein transport);GO:0006893(Golgi to plasma membrane transport);GO:0008104(protein localization);GO:0010008(endosome membrane);GO:0015031(protein transport);GO:0016020(membrane);GO:0016192(vesicle-mediated transport);GO:0030306(ADP-ribosylation factor binding);GO:0031901(early endosome membrane);GO:0032991(protein-containing complex);GO:0034394(protein localization to cell surface);GO:0042147(retrograde transport, endosome to Golgi);GO:0043001(Golgi to plasma membrane protein transport);GO:0043231(intracellular membrane-bounded organelle);GO:0044267(cellular protein metabolic process);GO:0045732(positive regulation of protein catabolic process);GO:0046982(protein heterodimerization activity);GO:1901998(toxin transport);GO:1903441(protein localization to ciliary membrane)","04142(Lysosome)","K12404","NA","golgi associated, gamma adaptin ear containing, ARF binding protein 1 [Source:HGNC Symbol;Acc:HGNC:17842]",{"v":0.489868,"d":"0.49"},{"v":0.406617,"d":"0.41"},{"v":0.280488,"d":"0.28"},{"v":0.406951,"d":"0.41"},{"v":0.491217,"d":"0.49"},{"v":0.625431,"d":"0.63"},{"v":0.772495256297753,"d":"0.77"},{"v":-0.37240202107646,"d":"-0.37"},1,1,"down","no"]
[207590,0,"chrX","-",154965772,154966516,"ENST00000483822",2,461,"ENSG00000185010","F8","GO:0000139(Golgi membrane);GO:0002576(platelet degranulation);GO:0005507(copper ion binding);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0005615(extracellular space);GO:0005788(endoplasmic reticulum lumen);GO:0005886(plasma membrane);GO:0006888(endoplasmic reticulum to Golgi vesicle-mediated transport);GO:0006953(acute-phase response);GO:0007596(blood coagulation);GO:0007597(blood coagulation, intrinsic pathway);GO:0007599(hemostasis);GO:0016491(oxidoreductase activity);GO:0030134(COPII-coated ER to Golgi transport vesicle);GO:0030168(platelet activation);GO:0031093(platelet alpha granule lumen);GO:0033116(endoplasmic reticulum-Golgi intermediate compartment membrane);GO:0046872(metal ion binding);GO:0048208(COPII vesicle coating);GO:0055114(oxidation-reduction process)","04610(Complement and coagulation cascades)","K03899","NA","coagulation factor VIII [Source:HGNC Symbol;Acc:HGNC:3546]",0,0,{"v":0.094975,"d":"0.09"},{"v":0.016573,"d":"0.02"},0,0,{"v":5.73070657092862,"d":"5.73"},{"v":2.51871302790547,"d":"2.52"},1,1,"up","no"]
[178817,0,"chr7","-",45816216,45819016,"ENST00000443330",1,2801,"ENSG00000235955","CICP20","NA","NA","NA","NA","capicua transcriptional repressor pseudogene 20 [Source:HGNC Symbol;Acc:HGNC:48830]",0,0,0,0,0,0,1,0,1,1,"no","no"]
[197206,0,"chr9","+",89332917,89339947,"ENST00000477484",5,617,"ENSG00000187742","SECISBP2","GO:0001514(selenocysteine incorporation);GO:0003723(RNA binding);GO:0003730(mRNA 3'-UTR binding);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005739(mitochondrion);GO:0006412(translation);GO:0021756(striatum development);GO:0035368(selenocysteine insertion sequence binding);GO:0043021(ribonucleoprotein complex binding);GO:0048666(neuron development);GO:1990904(ribonucleoprotein complex);GO:2000623(negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)","NA","K19539","NA","SECIS binding protein 2 [Source:HGNC Symbol;Acc:HGNC:30972]",{"v":0.073077,"d":"0.07"},{"v":0.213643,"d":"0.21"},{"v":0.106384,"d":"0.11"},{"v":0.069222,"d":"0.07"},{"v":0.129274,"d":"0.13"},{"v":0.060749,"d":"0.06"},{"v":1.51634168450693,"d":"1.52"},{"v":0.600594879498801,"d":"0.60"},1,1,"up","no"]
[34208,0,"chr11","+",74638614,74641062,"ENST00000532954",2,564,"ENSG00000077514","POLD3","GO:0000723(telomere maintenance);GO:0000731(DNA synthesis involved in DNA repair);GO:0003887(DNA-directed DNA polymerase activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0006260(DNA replication);GO:0006261(DNA-dependent DNA replication);GO:0006281(DNA repair);GO:0006283(transcription-coupled nucleotide-excision repair);GO:0006296(nucleotide-excision repair, DNA incision, 5'-to lesion);GO:0006297(nucleotide-excision repair, DNA gap filling);GO:0006298(mismatch repair);GO:0006974(cellular response to DNA damage stimulus);GO:0019985(translesion synthesis);GO:0032201(telomere maintenance via semi-conservative replication);GO:0033683(nucleotide-excision repair, DNA incision);GO:0042769(DNA damage response, detection of DNA damage);GO:0043625(delta DNA polymerase complex)","03030(DNA replication);03410(Base excision repair);03420(Nucleotide excision repair);03430(Mismatch repair);03440(Homologous recombination)","K03504","NA","DNA polymerase delta 3, accessory subunit [Source:HGNC Symbol;Acc:HGNC:20932]",0,0,0,0,0,0,1,0,1,1,"no","no"]
[25945,0,"chr11","+",827919,831986,"ENST00000525077",9,2166,"ENSG00000177685","CRACR2B","GO:0002115(store-operated calcium entry);GO:0005509(calcium ion binding);GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0034613(cellular protein localization);GO:2001256(regulation of store-operated calcium entry)","NA","K17199","NA","calcium release activated channel regulator 2B [Source:HGNC Symbol;Acc:HGNC:28703]",0,{"v":0.06743,"d":"0.07"},0,{"v":0.105563,"d":"0.11"},{"v":0.03284,"d":"0.03"},0,{"v":0.487200421956172,"d":"0.49"},{"v":-1.03741271214843,"d":"-1.04"},1,1,"down","no"]
[4348,0,"chr1","+",36176806,36179022,"ENST00000487131",5,733,"ENSG00000116871","MAP7D1","GO:0000226(microtubule cytoskeleton organization);GO:0005737(cytoplasm);GO:0005819(spindle);GO:0005829(cytosol);GO:0005856(cytoskeleton);GO:0015630(microtubule cytoskeleton)","NA","K16806","NA","MAP7 domain containing 1 [Source:HGNC Symbol;Acc:HGNC:25514]",0,0,{"v":0.661594,"d":"0.66"},0,{"v":0.51014,"d":"0.51"},0,{"v":1.29688712902341,"d":"1.30"},{"v":0.375052924089163,"d":"0.38"},1,1,"up","no"]
[127351,0,"chr20","-",45788211,45791868,"ENST00000465935",2,886,"ENSG00000124116","WFDC3","GO:0004867(serine-type endopeptidase inhibitor activity);GO:0005576(extracellular region);GO:0010466(negative regulation of peptidase activity);GO:0010951(negative regulation of endopeptidase activity);GO:0030414(peptidase inhibitor activity)","NA","NA","NA","WAP four-disulfide core domain 3 [Source:HGNC Symbol;Acc:HGNC:15957]",0,0,0,0,{"v":0.034051,"d":"0.03"},0,"-inf","-inf",1,1,"down","no"]
[45542,0,"chr12","+",68843066,68844190,"ENST00000544125",2,649,"ENSG00000135679","MDM2","GO:0000122(negative regulation of transcription by RNA polymerase II);GO:0001568(blood vessel development);GO:0001974(blood vessel remodeling);GO:0002027(regulation of heart rate);GO:0002039(p53 binding);GO:0003170(heart valve development);GO:0003181(atrioventricular valve morphogenesis);GO:0003203(endocardial cushion morphogenesis);GO:0003281(ventricular septum development);GO:0003283(atrial septum development);GO:0004842(ubiquitin-protein transferase activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005730(nucleolus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0006511(ubiquitin-dependent protein catabolic process);GO:0006977(DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest);GO:0007089(traversing start control point of mitotic cell cycle);GO:0007507(heart development);GO:0008097(5S rRNA binding);GO:0008270(zinc ion binding);GO:0008284(positive regulation of cell population proliferation);GO:0009636(response to toxic substance);GO:0010039(response to iron ion);GO:0010468(regulation of gene expression);GO:0010628(positive regulation of gene expression);GO:0010629(negative regulation of gene expression);GO:0010955(negative regulation of protein processing);GO:0010977(negative regulation of neuron projection development);GO:0016032(viral process);GO:0016567(protein ubiquitination);GO:0016579(protein deubiquitination);GO:0016604(nuclear body);GO:0016740(transferase activity);GO:0016874(ligase activity);GO:0016925(protein sumoylation);GO:0018205(peptidyl-lysine modification);GO:0019789(SUMO transferase activity);GO:0019899(enzyme binding);GO:0019904(protein domain specific binding);GO:0030666(endocytic vesicle membrane);GO:0031625(ubiquitin protein ligase binding);GO:0031648(protein destabilization);GO:0032026(response to magnesium ion);GO:0032436(positive regulation of proteasomal ubiquitin-dependent protein catabolic process);GO:0032991(protein-containing complex);GO:0033612(receptor serine/threonine kinase binding);GO:0034504(protein localization to nucleus);GO:0036369(transcription factor catabolic process);GO:0042176(regulation of protein catabolic process);GO:0042220(response to cocaine);GO:0042493(response to drug);GO:0042802(identical protein binding);GO:0042975(peroxisome proliferator activated receptor binding);GO:0043021(ribonucleoprotein complex binding);GO:0043066(negative regulation of apoptotic process);GO:0043130(ubiquitin binding);GO:0043154(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process);GO:0043278(response to morphine);GO:0043518(negative regulation of DNA damage response, signal transduction by p53 class mediator);GO:0045184(establishment of protein localization);GO:0045202(synapse);GO:0045472(response to ether);GO:0045787(positive regulation of cell cycle);GO:0045892(negative regulation of transcription, DNA-templated);GO:0045931(positive regulation of mitotic cell cycle);GO:0046677(response to antibiotic);GO:0046827(positive regulation of protein export from nucleus);GO:0046872(metal ion binding);GO:0047485(protein N-terminus binding);GO:0048545(response to steroid hormone);GO:0051603(proteolysis involved in cellular protein catabolic process);GO:0051865(protein autoubiquitination);GO:0060411(cardiac septum morphogenesis);GO:0061630(ubiquitin protein ligase activity);GO:0061663(NEDD8 ligase activity);GO:0065003(protein-containing complex assembly);GO:0070301(cellular response to hydrogen peroxide);GO:0071157(negative regulation of cell cycle arrest);GO:0071236(cellular response to antibiotic);GO:0071301(cellular response to vitamin B1);GO:0071310(cellular response to organic substance);GO:0071312(cellular response to alkaloid);GO:0071363(cellular response to growth factor stimulus);GO:0071375(cellular response to peptide hormone stimulus);GO:0071391(cellular response to estrogen stimulus);GO:0071407(cellular response to organic cyclic compound);GO:0071456(cellular response to hypoxia);GO:0071480(cellular response to gamma radiation);GO:0071494(cellular response to UV-C);GO:0072717(cellular response to actinomycin D);GO:0097110(scaffold protein binding);GO:0097718(disordered domain specific binding);GO:1901796(regulation of signal transduction by p53 class mediator);GO:1901797(negative regulation of signal transduction by p53 class mediator);GO:1902254(negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator);GO:1904404(response to formaldehyde);GO:1904707(positive regulation of vascular smooth muscle cell proliferation);GO:1904754(positive regulation of vascular associated smooth muscle cell migration);GO:1990000(amyloid fibril formation);GO:1990785(response to water-immersion restraint stress)","01522(Endocrine resistance);01524(Platinum drug resistance);04068(FoxO signaling pathway);04110(Cell cycle);04115(p53 signaling pathway);04120(Ubiquitin mediated proteolysis);04144(Endocytosis);04151(PI3K-Akt signaling pathway);04218(Cellular senescence);04625(C-type lectin receptor signaling pathway);04919(Thyroid hormone signaling pathway);05163(Human cytomegalovirus infection);05165(Human papillomavirus infection);05169(Epstein-Barr virus infection);05200(Pathways in cancer);05202(Transcriptional misregulation in cancer);05203(Viral carcinogenesis);05205(Proteoglycans in cancer);05206(MicroRNAs in cancer);05214(Glioma);05215(Prostate cancer);05218(Melanoma);05219(Bladder cancer);05220(Chronic myeloid leukemia)","K06643","EC:2.3.2.27","MDM2 proto-oncogene [Source:HGNC Symbol;Acc:HGNC:6973]",{"v":0.501016,"d":"0.50"},0,{"v":0.343806,"d":"0.34"},{"v":0.195645,"d":"0.20"},{"v":0.65979,"d":"0.66"},{"v":0.106297,"d":"0.11"},{"v":0.878438067985676,"d":"0.88"},{"v":-0.186987518567797,"d":"-0.19"},1,1,"down","no"]
[22839,0,"chr10","+",87843870,87844280,"ENST00000432948",1,411,"ENSG00000223820","CFL1P1","NA","NA","NA","NA","cofilin 1 pseudogene 1 [Source:HGNC Symbol;Acc:HGNC:28560]",0,0,0,0,0,0,1,0,1,1,"no","no"]
[110717,0,"chr2","-",27133124,27134636,"ENST00000416802",2,564,"ENSG00000138073","PREB","GO:0000139(Golgi membrane);GO:0003400(regulation of COPII vesicle coating);GO:0003677(DNA binding);GO:0005085(guanyl-nucleotide exchange factor activity);GO:0005090(Sar guanyl-nucleotide exchange factor activity);GO:0005096(GTPase activator activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0006888(endoplasmic reticulum to Golgi vesicle-mediated transport);GO:0009306(protein secretion);GO:0015031(protein transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016192(vesicle-mediated transport);GO:0030176(integral component of endoplasmic reticulum membrane);GO:0032527(protein exit from endoplasmic reticulum);GO:0036498(IRE1-mediated unfolded protein response);GO:0043547(positive regulation of GTPase activity);GO:0048208(COPII vesicle coating);GO:0050790(regulation of catalytic activity);GO:0051020(GTPase binding);GO:0070971(endoplasmic reticulum exit site)","04141(Protein processing in endoplasmic reticulum)","K14003","NA","prolactin regulatory element binding [Source:HGNC Symbol;Acc:HGNC:9356]",0,0,0,{"v":0.350167,"d":"0.35"},0,0,"-inf","-inf",1,1,"down","no"]
[124578,0,"chr20","-",2491841,2508915,"ENST00000381253",6,819,"ENSG00000088876","ZNF343","GO:0000981(DNA-binding transcription factor activity, RNA polymerase II-specific);GO:0003676(nucleic acid binding);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0005622(intracellular);GO:0005634(nucleus);GO:0006355(regulation of transcription, DNA-templated);GO:0006357(regulation of transcription by RNA polymerase II);GO:0046872(metal ion binding)","05168(Herpes simplex virus 1 infection)","K09228","NA","zinc finger protein 343 [Source:HGNC Symbol;Acc:HGNC:16017]",{"v":0.042678,"d":"0.04"},{"v":0.017911,"d":"0.02"},{"v":0.044738,"d":"0.04"},0,{"v":0.018868,"d":"0.02"},0,{"v":5.58230867076532,"d":"5.58"},{"v":2.48086189965843,"d":"2.48"},1,1,"up","no"]
[94536,0,"chr18","-",47130244,47150476,"ENST00000587388",5,566,"ENSG00000167220","HDHD2","GO:0005515(protein binding);GO:0008150(biological_process);GO:0016311(dephosphorylation);GO:0016791(phosphatase activity);GO:0019899(enzyme binding);GO:0046872(metal ion binding);GO:0070062(extracellular exosome)","NA","NA","NA","haloacid dehalogenase like hydrolase domain containing 2 [Source:HGNC Symbol;Acc:HGNC:25364]",0,0,{"v":0.005731,"d":"0.01"},0,{"v":0.025801,"d":"0.03"},0,{"v":0.222123173520406,"d":"0.22"},{"v":-2.17056818161095,"d":"-2.17"},1,1,"down","no"]
[140292,0,"chr3","-",50290181,50292056,"ENST00000468737",4,606,"ENSG00000214706","IFRD2","GO:0003674(molecular_function);GO:0005515(protein binding);GO:0005634(nucleus)","NA","NA","NA","interferon related developmental regulator 2 [Source:HGNC Symbol;Acc:HGNC:5457]",{"v":0.140856,"d":"0.14"},0,0,{"v":0.030757,"d":"0.03"},0,0,{"v":4.57964040706181,"d":"4.58"},{"v":2.19523432248913,"d":"2.20"},1,1,"up","no"]
[128098,0,"chr20","-",58245746,58309439,"ENST00000244070",10,1474,"ENSG00000124224","PPP4R1L","NA","NA","NA","NA","protein phosphatase 4 regulatory subunit 1 like (pseudogene) [Source:HGNC Symbol;Acc:HGNC:15755]",{"v":0.661294,"d":"0.66"},0,0,0,0,{"v":0.329788,"d":"0.33"},{"v":2.00520940725557,"d":"2.01"},{"v":1.00375290751991,"d":"1.00"},1,1,"up","no"]
[28690,0,"chr11","+",31509771,31650221,"ENST00000474374",9,1161,"ENSG00000109911","ELP4","GO:0000993(RNA polymerase II complex binding);GO:0002098(tRNA wobble uridine modification);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0006357(regulation of transcription by RNA polymerase II);GO:0006368(transcription elongation from RNA polymerase II promoter);GO:0008023(transcription elongation factor complex);GO:0008607(phosphorylase kinase regulator activity);GO:0033588(Elongator holoenzyme complex);GO:0045859(regulation of protein kinase activity)","NA","K11375","NA","elongator acetyltransferase complex subunit 4 [Source:HGNC Symbol;Acc:HGNC:1171]",0,0,0,{"v":0.098879,"d":"0.10"},0,0,"-inf","-inf",1,1,"down","no"]
[203999,0,"chrX","+",70290112,70297188,"ENST00000485406",4,671,"ENSG00000090889","KIF4A","GO:0000166(nucleotide binding);GO:0000281(mitotic cytokinesis);GO:0003677(DNA binding);GO:0003777(microtubule motor activity);GO:0005515(protein binding);GO:0005524(ATP binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005694(chromosome);GO:0005737(cytoplasm);GO:0005819(spindle);GO:0005829(cytosol);GO:0005856(cytoskeleton);GO:0005871(kinesin complex);GO:0005874(microtubule);GO:0005876(spindle microtubule);GO:0006890(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum);GO:0006996(organelle organization);GO:0007018(microtubule-based movement);GO:0007052(mitotic spindle organization);GO:0008017(microtubule binding);GO:0008089(anterograde axonal transport);GO:0016020(membrane);GO:0016363(nuclear matrix);GO:0016887(ATPase activity);GO:0019886(antigen processing and presentation of exogenous peptide antigen via MHC class II);GO:0030496(midbody);GO:0045171(intercellular bridge);GO:0051256(mitotic spindle midzone assembly);GO:1904115(axon cytoplasm)","NA","K10395","NA","kinesin family member 4A [Source:HGNC Symbol;Acc:HGNC:13339]",0,0,0,0,{"v":0.285928,"d":"0.29"},0,"-inf","-inf",1,1,"down","no"]
[134204,0,"chr22","-",36440880,36440970,"ENST00000516416",1,91,"ENSG00000252225","RF00019","NA","NA","NA","NA","NA",0,0,{"v":0.011994,"d":"0.01"},0,0,0,"inf","inf",1,1,"up","no"]
[29774,0,"chr11","-",47171525,47172186,"ENST00000526948",2,556,"ENSG00000149182","ARFGAP2","GO:0000139(Golgi membrane);GO:0005096(GTPase activator activity);GO:0005737(cytoplasm);GO:0005794(Golgi apparatus);GO:0005802(trans-Golgi network);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0006888(endoplasmic reticulum to Golgi vesicle-mediated transport);GO:0006890(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum);GO:0015031(protein transport);GO:0016020(membrane);GO:0016192(vesicle-mediated transport);GO:0030126(COPI vesicle coat);GO:0043547(positive regulation of GTPase activity);GO:0046872(metal ion binding);GO:0048205(COPI coating of Golgi vesicle)","04144(Endocytosis)","K12493","NA","ADP ribosylation factor GTPase activating protein 2 [Source:HGNC Symbol;Acc:HGNC:13504]",{"v":0.084066,"d":"0.08"},{"v":0.033407,"d":"0.03"},{"v":0.265488,"d":"0.27"},{"v":0.108158,"d":"0.11"},{"v":0.305681,"d":"0.31"},{"v":0.024637,"d":"0.02"},{"v":0.87339101798046,"d":"0.87"},{"v":-0.19530040047824,"d":"-0.20"},1,1,"down","no"]
[78801,0,"chr16","-",88813736,88856826,"ENST00000567525",12,1953,"ENSG00000141012","GALNS","GO:0003824(catalytic activity);GO:0003943(N-acetylgalactosamine-4-sulfatase activity);GO:0005576(extracellular region);GO:0005764(lysosome);GO:0008484(sulfuric ester hydrolase activity);GO:0016787(hydrolase activity);GO:0035578(azurophil granule lumen);GO:0042340(keratan sulfate catabolic process);GO:0043202(lysosomal lumen);GO:0043312(neutrophil degranulation);GO:0043890(N-acetylgalactosamine-6-sulfatase activity);GO:0046872(metal ion binding);GO:0070062(extracellular exosome)","00531(Glycosaminoglycan degradation);04142(Lysosome)","NA","NA","galactosamine (N-acetyl)-6-sulfatase [Source:HGNC Symbol;Acc:HGNC:4122]",{"v":0.093611,"d":"0.09"},0,{"v":11.542123,"d":"11.54"},{"v":0.013521,"d":"0.01"},{"v":0.037976,"d":"0.04"},{"v":0.053167,"d":"0.05"},{"v":111.172265535428,"d":"111.17"},{"v":6.79665310944508,"d":"6.80"},1,1,"up","no"]
[134074,0,"chr22","-",35336721,35336799,"ENST00000620069",1,79,"ENSG00000274280","MIR6069","NA","NA","NA","NA","microRNA 6069 [Source:HGNC Symbol;Acc:HGNC:50124]",0,0,0,0,{"v":0.142045,"d":"0.14"},0,"-inf","-inf",1,1,"down","no"]
[159302,0,"chr5","+",60945335,61153026,"ENST00000502658",3,461,"ENSG00000164182","NDUFAF2","GO:0005739(mitochondrion);GO:0005743(mitochondrial inner membrane);GO:0008137(NADH dehydrogenase (ubiquinone) activity);GO:0009055(electron transfer activity);GO:0016020(membrane);GO:0022904(respiratory electron transport chain);GO:0032981(mitochondrial respiratory chain complex I assembly);GO:0045333(cellular respiration);GO:0061179(negative regulation of insulin secretion involved in cellular response to glucose stimulus);GO:0072593(reactive oxygen species metabolic process)","04714(Thermogenesis)","K18160","NA","NADH:ubiquinone oxidoreductase complex assembly factor 2 [Source:HGNC Symbol;Acc:HGNC:28086]",{"v":0.783625,"d":"0.78"},{"v":0.709685,"d":"0.71"},{"v":0.569696,"d":"0.57"},{"v":0.926034,"d":"0.93"},{"v":0.464677,"d":"0.46"},{"v":0.07569,"d":"0.08"},{"v":1.40684983166269,"d":"1.41"},{"v":0.492468342307443,"d":"0.49"},1,1,"up","no"]
[161917,0,"chr5","+",119167629,119170535,"ENST00000504497",2,582,"ENSG00000172869","DMXL1","GO:0005515(protein binding);GO:0007035(vacuolar acidification);GO:0043291(RAVE complex)","NA","NA","NA","Dmx like 1 [Source:HGNC Symbol;Acc:HGNC:2937]",{"v":1.356749,"d":"1.36"},{"v":0.155673,"d":"0.16"},{"v":1.048414,"d":"1.05"},{"v":1.561121,"d":"1.56"},{"v":1.258179,"d":"1.26"},{"v":1.280482,"d":"1.28"},{"v":0.624627358235145,"d":"0.62"},{"v":-0.678932335125756,"d":"-0.68"},1,1,"down","no"]
[169060,0,"chr6","-",31639028,31640539,"ENST00000464126",4,609,"ENSG00000204463","BAG6","GO:0001822(kidney development);GO:0002376(immune system process);GO:0002429(immune response-activating cell surface receptor signaling pathway);GO:0005102(signaling receptor binding);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0006325(chromatin organization);GO:0006511(ubiquitin-dependent protein catabolic process);GO:0006915(apoptotic process);GO:0007130(synaptonemal complex assembly);GO:0007283(spermatogenesis);GO:0007420(brain development);GO:0010498(proteasomal protein catabolic process);GO:0016020(membrane);GO:0018393(internal peptidyl-lysine acetylation);GO:0030101(natural killer cell activation);GO:0030154(cell differentiation);GO:0030324(lung development);GO:0030433(ubiquitin-dependent ERAD pathway);GO:0030544(Hsp70 protein binding);GO:0031593(polyubiquitin modification-dependent protein binding);GO:0031625(ubiquitin protein ligase binding);GO:0032435(negative regulation of proteasomal ubiquitin-dependent protein catabolic process);GO:0042127(regulation of cell population proliferation);GO:0042771(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator);GO:0042981(regulation of apoptotic process);GO:0043022(ribosome binding);GO:0043066(negative regulation of apoptotic process);GO:0043161(proteasome-mediated ubiquitin-dependent protein catabolic process);GO:0043231(intracellular membrane-bounded organelle);GO:0045861(negative regulation of proteolysis);GO:0045995(regulation of embryonic development);GO:0050821(protein stabilization);GO:0051787(misfolded protein binding);GO:0061857(endoplasmic reticulum stress-induced pre-emptive quality control);GO:0070059(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress);GO:0070062(extracellular exosome);GO:0070628(proteasome binding);GO:0071712(ER-associated misfolded protein catabolic process);GO:0071816(tail-anchored membrane protein insertion into ER membrane);GO:0071818(BAT3 complex);GO:1904294(positive regulation of ERAD pathway);GO:1904378(maintenance of unfolded protein involved in ERAD pathway);GO:1904379(protein localization to cytosolic proteasome complex involved in ERAD pathway);GO:1990381(ubiquitin-specific protease binding)","NA","NA","NA","BCL2 associated athanogene 6 [Source:HGNC Symbol;Acc:HGNC:13919]",{"v":0.325101,"d":"0.33"},{"v":0.040454,"d":"0.04"},{"v":0.056006,"d":"0.06"},{"v":0.198121,"d":"0.20"},{"v":0.404781,"d":"0.40"},{"v":0.269118,"d":"0.27"},{"v":0.483430425907663,"d":"0.48"},{"v":-1.04861981929165,"d":"-1.05"},1,1,"down","no"]
[193683,0,"chr8","-",143985914,143986932,"ENST00000531707",4,500,"ENSG00000178685","PARP10","GO:0003676(nucleic acid binding);GO:0003950(NAD+ ADP-ribosyltransferase activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005730(nucleolus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0006281(DNA repair);GO:0006471(protein ADP-ribosylation);GO:0006974(cellular response to DNA damage stimulus);GO:0010629(negative regulation of gene expression);GO:0010847(regulation of chromatin assembly);GO:0016740(transferase activity);GO:0016757(transferase activity, transferring glycosyl groups);GO:0019985(translesion synthesis);GO:0032088(negative regulation of NF-kappaB transcription factor activity);GO:0034356(NAD biosynthesis via nicotinamide riboside salvage pathway);GO:0043231(intracellular membrane-bounded organelle);GO:0045071(negative regulation of viral genome replication);GO:0048147(negative regulation of fibroblast proliferation);GO:0070212(protein poly-ADP-ribosylation);GO:0070213(protein auto-ADP-ribosylation);GO:0070530(K63-linked polyubiquitin modification-dependent protein binding);GO:0140289(protein mono-ADP-ribosylation);GO:1900045(negative regulation of protein K63-linked ubiquitination);GO:1990404(protein ADP-ribosylase activity)","NA","K15261","EC:2.4.2.30","poly(ADP-ribose) polymerase family member 10 [Source:HGNC Symbol;Acc:HGNC:25895]",0,0,0,0,0,0,1,0,1,1,"no","no"]
[191488,0,"chr8","-",100718087,100722749,"ENST00000521865",4,628,"ENSG00000070756","PABPC1","GO:0000184(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay);GO:0000398(mRNA splicing, via spliceosome);GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0003730(mRNA 3'-UTR binding);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005681(spliceosomal complex);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005925(focal adhesion);GO:0006378(mRNA polyadenylation);GO:0006397(mRNA processing);GO:0006413(translational initiation);GO:0008022(protein C-terminus binding);GO:0008143(poly(A) binding);GO:0008266(poly(U) RNA binding);GO:0008380(RNA splicing);GO:0008494(translation activator activity);GO:0010494(cytoplasmic stress granule);GO:0016020(membrane);GO:0031047(gene silencing by RNA);GO:0036464(cytoplasmic ribonucleoprotein granule);GO:0043488(regulation of mRNA stability);GO:0045070(positive regulation of viral genome replication);GO:0045727(positive regulation of translation);GO:0048255(mRNA stabilization);GO:0060213(positive regulation of nuclear-transcribed mRNA poly(A) tail shortening);GO:0070062(extracellular exosome);GO:0071013(catalytic step 2 spliceosome);GO:1900153(positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay);GO:1990904(ribonucleoprotein complex);GO:2000623(negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)","03013(RNA transport);03015(mRNA surveillance pathway);03018(RNA degradation)","K13126","NA","poly(A) binding protein cytoplasmic 1 [Source:HGNC Symbol;Acc:HGNC:8554]",0,0,0,{"v":0.468366,"d":"0.47"},{"v":0.237881,"d":"0.24"},{"v":0.427418,"d":"0.43"},"-inf","-inf",1,1,"down","no"]
[197732,0,"chr9","-",96844946,96875623,"ENST00000498811",6,698,"ENSG00000196597","ZNF782","GO:0000981(DNA-binding transcription factor activity, RNA polymerase II-specific);GO:0003676(nucleic acid binding);GO:0003677(DNA binding);GO:0005622(intracellular);GO:0005634(nucleus);GO:0006355(regulation of transcription, DNA-templated);GO:0006357(regulation of transcription by RNA polymerase II);GO:0046872(metal ion binding)","05168(Herpes simplex virus 1 infection)","K09228","NA","zinc finger protein 782 [Source:HGNC Symbol;Acc:HGNC:33110]",0,0,0,0,0,{"v":0.099058,"d":"0.10"},"-inf","-inf",1,1,"down","no"]
[7965,0,"chr1","-",86352859,86356544,"ENST00000531412",6,534,"ENSG00000122417","ODF2L","GO:0005737(cytoplasm);GO:0005813(centrosome);GO:0005814(centriole);GO:0005815(microtubule organizing center);GO:0005856(cytoskeleton);GO:0030030(cell projection organization);GO:0034451(centriolar satellite);GO:0036064(ciliary basal body);GO:0042995(cell projection);GO:1902018(negative regulation of cilium assembly)","NA","NA","NA","outer dense fiber of sperm tails 2 like [Source:HGNC Symbol;Acc:HGNC:29225]",{"v":0.160921,"d":"0.16"},{"v":0.289683,"d":"0.29"},{"v":0.0623,"d":"0.06"},{"v":0.061597,"d":"0.06"},{"v":0.111534,"d":"0.11"},{"v":0.267513,"d":"0.27"},{"v":1.16398725501766,"d":"1.16"},{"v":0.219075261662444,"d":"0.22"},1,1,"up","no"]
[97588,0,"chr19","-",5612520,5624046,"ENST00000590262",6,564,"ENSG00000130254","SAFB2","GO:0003676(nucleic acid binding);GO:0003677(DNA binding);GO:0003723(RNA binding);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0006355(regulation of transcription, DNA-templated);GO:0006357(regulation of transcription by RNA polymerase II);GO:0016604(nuclear body);GO:0042802(identical protein binding);GO:0043231(intracellular membrane-bounded organelle);GO:0043565(sequence-specific DNA binding);GO:0050684(regulation of mRNA processing);GO:0060008(Sertoli cell differentiation);GO:0060765(regulation of androgen receptor signaling pathway);GO:0070062(extracellular exosome)","NA","NA","NA","scaffold attachment factor B2 [Source:HGNC Symbol;Acc:HGNC:21605]",{"v":0.130946,"d":"0.13"},{"v":0.22443,"d":"0.22"},{"v":0.164116,"d":"0.16"},{"v":0.333457,"d":"0.33"},{"v":0.149082,"d":"0.15"},{"v":0.2121,"d":"0.21"},{"v":0.747858959833813,"d":"0.75"},{"v":-0.419161879766787,"d":"-0.42"},1,1,"down","no"]
[104540,0,"chr19","+",42302132,42310821,"ENST00000341747",3,1530,"ENSG00000188368","PRR19","GO:0005515(protein binding)","NA","NA","NA","proline rich 19 [Source:HGNC Symbol;Acc:HGNC:33728]",{"v":0.454097,"d":"0.45"},{"v":0.372794,"d":"0.37"},0,0,{"v":0.290213,"d":"0.29"},0,{"v":2.84925554678805,"d":"2.85"},{"v":1.5105850212933,"d":"1.51"},1,1,"up","no"]
[109353,0,"chr2","-",1643392,1646170,"ENST00000477093",3,570,"ENSG00000130508","PXDN","GO:0001960(negative regulation of cytokine-mediated signaling pathway);GO:0004601(peroxidase activity);GO:0005152(interleukin-1 receptor antagonist activity);GO:0005201(extracellular matrix structural constituent);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0005615(extracellular space);GO:0005783(endoplasmic reticulum);GO:0006955(immune response);GO:0006979(response to oxidative stress);GO:0016491(oxidoreductase activity);GO:0020037(heme binding);GO:0030198(extracellular matrix organization);GO:0042744(hydrogen peroxide catabolic process);GO:0046872(metal ion binding);GO:0055114(oxidation-reduction process);GO:0062023(collagen-containing extracellular matrix);GO:0070062(extracellular exosome);GO:0098869(cellular oxidant detoxification)","NA","K19511","EC:1.11.1.7","peroxidasin [Source:HGNC Symbol;Acc:HGNC:14966]",0,0,0,{"v":0.072074,"d":"0.07"},0,0,"-inf","-inf",1,1,"down","no"]
[4598,0,"chr1","+",39105429,39254648,"ENST00000467673",4,792,"ENSG00000127603","MACF1","GO:0003723(RNA binding);GO:0003779(actin binding);GO:0005198(structural molecule activity);GO:0005509(calcium ion binding);GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0005794(Golgi apparatus);GO:0005856(cytoskeleton);GO:0005874(microtubule);GO:0005882(intermediate filament);GO:0005886(plasma membrane);GO:0007010(cytoskeleton organization);GO:0008017(microtubule binding);GO:0008092(cytoskeletal protein binding);GO:0010632(regulation of epithelial cell migration);GO:0015629(actin cytoskeleton);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016055(Wnt signaling pathway);GO:0016887(ATPase activity);GO:0030054(cell junction);GO:0030177(positive regulation of Wnt signaling pathway);GO:0030334(regulation of cell migration);GO:0032587(ruffle membrane);GO:0032886(regulation of microtubule-based process);GO:0042060(wound healing);GO:0042995(cell projection);GO:0043001(Golgi to plasma membrane protein transport);GO:0045104(intermediate filament cytoskeleton organization);GO:0045296(cadherin binding);GO:0045773(positive regulation of axon extension);GO:0046872(metal ion binding);GO:0051011(microtubule minus-end binding);GO:0051015(actin filament binding);GO:0051893(regulation of focal adhesion assembly)","NA","K19827","NA","microtubule-actin crosslinking factor 1 [Source:HGNC Symbol;Acc:HGNC:13664]",{"v":0.065774,"d":"0.07"},{"v":0.16918,"d":"0.17"},{"v":0.102042,"d":"0.10"},{"v":0.022085,"d":"0.02"},{"v":0.234134,"d":"0.23"},{"v":0.00621,"d":"0.01"},{"v":1.28414161544646,"d":"1.28"},{"v":0.360804311990083,"d":"0.36"},1,1,"up","no"]
[158754,0,"chr5","-",43445893,43483893,"ENST00000511525",3,629,"ENSG00000151881","TMEM267","GO:0016020(membrane);GO:0016021(integral component of membrane)","NA","NA","NA","transmembrane protein 267 [Source:HGNC Symbol;Acc:HGNC:26139]",{"v":0.092033,"d":"0.09"},{"v":0.03682,"d":"0.04"},0,0,0,0,"inf","inf",1,1,"up","no"]
[198131,0,"chr9","+",105575005,105620146,"ENST00000642644",10,1579,"ENSG00000106692","FKTN","GO:0000139(Golgi membrane);GO:0005515(protein binding);GO:0005615(extracellular space);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005783(endoplasmic reticulum);GO:0005794(Golgi apparatus);GO:0005801(cis-Golgi network);GO:0006486(protein glycosylation);GO:0006493(protein O-linked glycosylation);GO:0007399(nervous system development);GO:0007517(muscle organ development);GO:0008285(negative regulation of cell population proliferation);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016740(transferase activity);GO:0030173(integral component of Golgi membrane);GO:0035269(protein O-linked mannosylation);GO:0046329(negative regulation of JNK cascade);GO:0060049(regulation of protein glycosylation)","00515(Mannose type O-glycan biosynthesis)","NA","NA","fukutin [Source:HGNC Symbol;Acc:HGNC:3622]",{"v":0.00745,"d":"0.01"},{"v":0.011274,"d":"0.01"},{"v":0.185067,"d":"0.19"},{"v":0.146538,"d":"0.15"},0,{"v":0.005891,"d":"0.01"},{"v":1.33695687828432,"d":"1.34"},{"v":0.418952934026154,"d":"0.42"},1,1,"up","no"]
[127111,0,"chr20","+",44614308,44619037,"ENST00000349959",2,1153,"ENSG00000168734","PKIG","GO:0000122(negative regulation of transcription by RNA polymerase II);GO:0004860(protein kinase inhibitor activity);GO:0004862(cAMP-dependent protein kinase inhibitor activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0006469(negative regulation of protein kinase activity);GO:0007165(signal transduction);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0042308(negative regulation of protein import into nucleus);GO:0071901(negative regulation of protein serine/threonine kinase activity);GO:2000480(negative regulation of cAMP-dependent protein kinase activity)","NA","NA","NA","cAMP-dependent protein kinase inhibitor gamma [Source:HGNC Symbol;Acc:HGNC:9019]",{"v":0.203264,"d":"0.20"},{"v":0.056252,"d":"0.06"},{"v":0.064584,"d":"0.06"},{"v":0.249162,"d":"0.25"},{"v":0.198528,"d":"0.20"},{"v":0.057694,"d":"0.06"},{"v":0.64129454038909,"d":"0.64"},{"v":-0.640940969930762,"d":"-0.64"},1,1,"down","no"]
[201726,0,"chrX","-",16588003,16712217,"ENST00000443824",19,4319,"ENSG00000047230","CTPS2","GO:0000166(nucleotide binding);GO:0003883(CTP synthase activity);GO:0005515(protein binding);GO:0005524(ATP binding);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0006220(pyrimidine nucleotide metabolic process);GO:0006221(pyrimidine nucleotide biosynthetic process);GO:0006241(CTP biosynthetic process);GO:0006541(glutamine metabolic process);GO:0015949(nucleobase-containing small molecule interconversion);GO:0016874(ligase activity);GO:0019856(pyrimidine nucleobase biosynthetic process);GO:0042802(identical protein binding);GO:0044210('de novo' CTP biosynthetic process);GO:0097268(cytoophidium)","00240(Pyrimidine metabolism)","K01937","EC:6.3.4.2","CTP synthase 2 [Source:HGNC Symbol;Acc:HGNC:2520]",0,0,0,0,0,{"v":1.119954,"d":"1.12"},"-inf","-inf",1,1,"down","no"]
[194664,0,"chr9","-",14775935,14792801,"ENST00000466679",4,741,"ENSG00000164946","FREM1","GO:0005576(extracellular region);GO:0005604(basement membrane);GO:0007154(cell communication);GO:0007155(cell adhesion);GO:0007160(cell-matrix adhesion);GO:0007275(multicellular organism development);GO:0016021(integral component of membrane);GO:0030246(carbohydrate binding);GO:0046872(metal ion binding);GO:0097094(craniofacial suture morphogenesis)","NA","NA","NA","FRAS1 related extracellular matrix 1 [Source:HGNC Symbol;Acc:HGNC:23399]",0,0,0,0,0,{"v":0.040361,"d":"0.04"},"-inf","-inf",1,1,"down","no"]
[85651,0,"chr17","-",42192739,42194487,"ENST00000588352",5,559,"ENSG00000167925","GHDC","GO:0003674(molecular_function);GO:0005576(extracellular region);GO:0005634(nucleus);GO:0005635(nuclear envelope);GO:0005783(endoplasmic reticulum);GO:0008150(biological_process);GO:0016020(membrane);GO:0034774(secretory granule lumen);GO:0035580(specific granule lumen);GO:0043312(neutrophil degranulation)","NA","NA","NA","GH3 domain containing [Source:HGNC Symbol;Acc:HGNC:24438]",0,0,0,0,0,0,1,0,1,1,"no","no"]
[118238,0,"chr2","-",152679129,152693111,"ENST00000467114",4,546,"ENSG00000196504","PRPF40A","GO:0000398(mRNA splicing, via spliceosome);GO:0003723(RNA binding);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005685(U1 snRNP);GO:0005829(cytosol);GO:0006397(mRNA processing);GO:0007010(cytoskeleton organization);GO:0007049(cell cycle);GO:0008360(regulation of cell shape);GO:0008380(RNA splicing);GO:0016020(membrane);GO:0016363(nuclear matrix);GO:0016477(cell migration);GO:0016607(nuclear speck);GO:0032465(regulation of cytokinesis);GO:0045292(mRNA cis splicing, via spliceosome);GO:0051301(cell division);GO:0070064(proline-rich region binding);GO:0071004(U2-type prespliceosome)","03040(Spliceosome)","K12821","NA","pre-mRNA processing factor 40 homolog A [Source:HGNC Symbol;Acc:HGNC:16463]",{"v":0.289393,"d":"0.29"},{"v":0.211783,"d":"0.21"},{"v":0.16276,"d":"0.16"},{"v":0.080818,"d":"0.08"},{"v":0.147183,"d":"0.15"},{"v":0.00728,"d":"0.01"},{"v":2.8218853201066,"d":"2.82"},{"v":1.49665935878021,"d":"1.50"},1,1,"up","no"]
[192771,0,"chr8","-",130360689,130401915,"ENST00000520625",3,606,"ENSG00000153317","ASAP1","GO:0001786(phosphatidylserine binding);GO:0002102(podosome);GO:0005096(GTPase activator activity);GO:0005515(protein binding);GO:0005546(phosphatidylinositol-4,5-bisphosphate binding);GO:0005547(phosphatidylinositol-3,4,5-trisphosphate binding);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0016020(membrane);GO:0030030(cell projection organization);GO:0031253(cell projection membrane);GO:0043197(dendritic spine);GO:0043547(positive regulation of GTPase activity);GO:0045296(cadherin binding);GO:0046872(metal ion binding);GO:0060271(cilium assembly);GO:0061000(negative regulation of dendritic spine development);GO:0071803(positive regulation of podosome assembly);GO:1903527(positive regulation of membrane tubulation)","04144(Endocytosis);04666(Fc gamma R-mediated phagocytosis)","K12488","NA","ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 [Source:HGNC Symbol;Acc:HGNC:2720]",{"v":0.220789,"d":"0.22"},{"v":0.401611,"d":"0.40"},{"v":0.217665,"d":"0.22"},{"v":0.234942,"d":"0.23"},{"v":0.301722,"d":"0.30"},{"v":0.069187,"d":"0.07"},{"v":1.38658680104514,"d":"1.39"},{"v":0.471537932654086,"d":"0.47"},1,1,"up","no"]
[80434,0,"chr17","-",5514754,5583957,"ENST00000577119",15,4200,"ENSG00000091592","NLRP1","GO:0000166(nucleotide binding);GO:0002376(immune system process);GO:0005515(protein binding);GO:0005524(ATP binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0006915(apoptotic process);GO:0006919(activation of cysteine-type endopeptidase activity involved in apoptotic process);GO:0006954(inflammatory response);GO:0008656(cysteine-type endopeptidase activator activity involved in apoptotic process);GO:0016032(viral process);GO:0019899(enzyme binding);GO:0019904(protein domain specific binding);GO:0032495(response to muramyl dipeptide);GO:0042742(defense response to bacterium);GO:0042981(regulation of apoptotic process);GO:0043280(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process);GO:0045087(innate immune response);GO:0050718(positive regulation of interleukin-1 beta secretion);GO:0050727(regulation of inflammatory response);GO:0051402(neuron apoptotic process);GO:0061702(inflammasome complex);GO:0072558(NLRP1 inflammasome complex);GO:1904784(NLRP1 inflammasome complex assembly)","04621(NOD-like receptor signaling pathway)","K12798","NA","NLR family pyrin domain containing 1 [Source:HGNC Symbol;Acc:HGNC:14374]",0,0,0,0,0,{"v":0.69995,"d":"0.70"},"-inf","-inf",1,1,"down","no"]
[81015,0,"chr17","-",7581964,7584072,"ENST00000415124",2,352,"ENSG00000233223","AC016876","NA","NA","NA","NA","novel transcript, antisense to MPDU1 and CD68",{"v":0.276154,"d":"0.28"},{"v":0.36842,"d":"0.37"},{"v":0.507631,"d":"0.51"},{"v":0.401573,"d":"0.40"},{"v":0.597529,"d":"0.60"},{"v":0.285018,"d":"0.29"},{"v":0.897272061801078,"d":"0.90"},{"v":-0.156382603945802,"d":"-0.16"},1,1,"down","no"]
[193066,0,"chr8","-",139600839,139702956,"ENST00000649473",4,5062,"ENSG00000169427","KCNK9","GO:0005249(voltage-gated potassium channel activity);GO:0005267(potassium channel activity);GO:0005886(plasma membrane);GO:0005887(integral component of plasma membrane);GO:0006811(ion transport);GO:0006813(potassium ion transport);GO:0008021(synaptic vesicle);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0022841(potassium ion leak channel activity);GO:0030322(stabilization of membrane potential);GO:0071805(potassium ion transmembrane transport)","04925(Aldosterone synthesis and secretion)","K04919","NA","potassium two pore domain channel subfamily K member 9 [Source:HGNC Symbol;Acc:HGNC:6283]",0,0,0,0,0,{"v":0.00785,"d":"0.01"},"-inf","-inf",1,1,"down","no"]
[63084,0,"chr15","+",41284006,41297290,"ENST00000561275",4,821,"ENSG00000247556","OIP5-AS1","NA","NA","NA","NA","OIP5 antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:43563]",{"v":0.025573,"d":"0.03"},{"v":0.017487,"d":"0.02"},{"v":0.084549,"d":"0.08"},{"v":0.248533,"d":"0.25"},{"v":0.189113,"d":"0.19"},0,{"v":0.291580409737551,"d":"0.29"},{"v":-1.77803430157334,"d":"-1.78"},1,1,"down","no"]
[126203,0,"chr20","+",34876580,34913503,"ENST00000480274",4,567,"ENSG00000131069","ACSS2","GO:0000166(nucleotide binding);GO:0003824(catalytic activity);GO:0003987(acetate-CoA ligase activity);GO:0005524(ATP binding);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0005759(mitochondrial matrix);GO:0005829(cytosol);GO:0006069(ethanol oxidation);GO:0006085(acetyl-CoA biosynthetic process);GO:0008610(lipid biosynthetic process);GO:0016208(AMP binding);GO:0016874(ligase activity);GO:0019413(acetate biosynthetic process);GO:0019427(acetyl-CoA biosynthetic process from acetate);GO:0019542(propionate biosynthetic process);GO:0043231(intracellular membrane-bounded organelle)","00010(Glycolysis / Gluconeogenesis);00620(Pyruvate metabolism);00630(Glyoxylate and dicarboxylate metabolism);00640(Propanoate metabolism)","K01895","EC:6.2.1.1","acyl-CoA synthetase short chain family member 2 [Source:HGNC Symbol;Acc:HGNC:15814]",{"v":0.001838,"d":"0.00"},{"v":0.570957,"d":"0.57"},{"v":0.444046,"d":"0.44"},{"v":0.108772,"d":"0.11"},{"v":1.11937,"d":"1.12"},{"v":0.303899,"d":"0.30"},{"v":0.663716571553895,"d":"0.66"},{"v":-0.59136079926118,"d":"-0.59"},1,1,"down","no"]
[9735,0,"chr1","+",113905409,113914072,"ENST00000466480",4,3199,"ENSG00000118655","DCLRE1B","GO:0000723(telomere maintenance);GO:0000781(chromosome, telomeric region);GO:0000784(nuclear chromosome, telomeric region);GO:0003684(damaged DNA binding);GO:0004518(nuclease activity);GO:0004527(exonuclease activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005694(chromosome);GO:0005737(cytoplasm);GO:0005813(centrosome);GO:0005815(microtubule organizing center);GO:0005856(cytoskeleton);GO:0006281(DNA repair);GO:0006303(double-strand break repair via nonhomologous end joining);GO:0006974(cellular response to DNA damage stimulus);GO:0007093(mitotic cell cycle checkpoint);GO:0008409(5'-3' exonuclease activity);GO:0010833(telomere maintenance via telomere lengthening);GO:0016233(telomere capping);GO:0016604(nuclear body);GO:0016787(hydrolase activity);GO:0031627(telomeric loop formation);GO:0031848(protection from non-homologous end joining at telomere);GO:0031860(telomeric 3' overhang formation);GO:0035312(5'-3' exodeoxyribonuclease activity);GO:0036297(interstrand cross-link repair);GO:0042803(protein homodimerization activity);GO:0044877(protein-containing complex binding);GO:0090305(nucleic acid phosphodiester bond hydrolysis)","NA","K15341","EC:3.1.-.-","DNA cross-link repair 1B [Source:HGNC Symbol;Acc:HGNC:17641]",0,0,0,0,{"v":0.112049,"d":"0.11"},{"v":0.074137,"d":"0.07"},"-inf","-inf",1,1,"down","no"]
[114119,0,"chr2","-",74523339,74524256,"ENST00000495597",2,589,"ENSG00000144045","DQX1","GO:0000166(nucleotide binding);GO:0003723(RNA binding);GO:0004386(helicase activity);GO:0005524(ATP binding);GO:0005634(nucleus);GO:0016787(hydrolase activity);GO:0034459(ATP-dependent 3'-5' RNA helicase activity)","NA","K14433","EC:3.6.4.13","DEAQ-box RNA dependent ATPase 1 [Source:HGNC Symbol;Acc:HGNC:20410]",0,0,0,0,0,0,1,0,1,1,"no","no"]
[177408,0,"chr7","-",25123444,25125260,"ENST00000409764",4,799,"ENSG00000172115","CYCS","GO:0000159(protein phosphatase type 2A complex);GO:0004722(protein serine/threonine phosphatase activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005739(mitochondrion);GO:0005743(mitochondrial inner membrane);GO:0005758(mitochondrial intermembrane space);GO:0005829(cytosol);GO:0006122(mitochondrial electron transport, ubiquinol to cytochrome c);GO:0006123(mitochondrial electron transport, cytochrome c to oxygen);GO:0006470(protein dephosphorylation);GO:0006915(apoptotic process);GO:0007005(mitochondrion organization);GO:0008635(activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c);GO:0009055(electron transfer activity);GO:0020037(heme binding);GO:0022900(electron transport chain);GO:0034599(cellular response to oxidative stress);GO:0045155(electron transporter, transferring electrons from CoQH2-cytochrome c reductase complex and cytochrome c oxidase complex activity);GO:0045333(cellular respiration);GO:0046872(metal ion binding);GO:0055114(oxidation-reduction process);GO:0070469(respirasome)","01524(Platinum drug resistance);04115(p53 signaling pathway);04210(Apoptosis);04215(Apoptosis - multiple species);04932(Non-alcoholic fatty liver disease (NAFLD));05010(Alzheimer disease);05012(Parkinson disease);05014(Amyotrophic lateral sclerosis (ALS));05016(Huntington disease);05134(Legionellosis);05145(Toxoplasmosis);05152(Tuberculosis);05160(Hepatitis C);05161(Hepatitis B);05162(Measles);05163(Human cytomegalovirus infection);05164(Influenza A);05167(Kaposi sarcoma-associated herpesvirus infection);05168(Herpes simplex virus 1 infection);05169(Epstein-Barr virus infection);05170(Human immunodeficiency virus 1 infection);05200(Pathways in cancer);05210(Colorectal cancer);05222(Small cell lung cancer);05416(Viral myocarditis)","K08738","NA","cytochrome c, somatic [Source:HGNC Symbol;Acc:HGNC:19986]",0,0,0,{"v":0.022021,"d":"0.02"},0,0,"-inf","-inf",1,1,"down","no"]
[104866,0,"chr19","+",43978376,43978663,"ENST00000619673",1,288,"ENSG00000278492","AC006213","NA","NA","NA","NA","novel transcript, sense intronic to ZNF155",{"v":0.410517,"d":"0.41"},{"v":0.593342,"d":"0.59"},{"v":1.015077,"d":"1.02"},{"v":0.628532,"d":"0.63"},{"v":0.467564,"d":"0.47"},{"v":0.268074,"d":"0.27"},{"v":1.47997390354575,"d":"1.48"},{"v":0.565571736964313,"d":"0.57"},1,1,"up","no"]
[146128,0,"chr3","-",161086559,161105289,"ENST00000492353",6,662,"ENSG00000169255","B3GALNT1","GO:0000139(Golgi membrane);GO:0005783(endoplasmic reticulum);GO:0005794(Golgi apparatus);GO:0006486(protein glycosylation);GO:0006487(protein N-linked glycosylation);GO:0006687(glycosphingolipid metabolic process);GO:0008376(acetylgalactosaminyltransferase activity);GO:0008378(galactosyltransferase activity);GO:0008499(UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity);GO:0009312(oligosaccharide biosynthetic process);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016740(transferase activity);GO:0016757(transferase activity, transferring glycosyl groups);GO:0047273(galactosylgalactosylglucosylceramide beta-D-acetylgalactosaminyltransferase activity)","00601(Glycosphingolipid biosynthesis - lacto and neolacto series);00603(Glycosphingolipid biosynthesis - globo and isoglobo series)","K00719","EC:2.4.1.79","beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group) [Source:HGNC Symbol;Acc:HGNC:918]",0,{"v":0.071442,"d":"0.07"},{"v":0.029178,"d":"0.03"},0,0,{"v":0.073078,"d":"0.07"},{"v":1.37688497222146,"d":"1.38"},{"v":0.461408038821193,"d":"0.46"},1,1,"up","no"]
[29331,0,"chr11","+",43448603,43494927,"ENST00000525543",5,3142,"ENSG00000052841","TTC17","GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005856(cytoskeleton);GO:0005886(plasma membrane);GO:0015629(actin cytoskeleton);GO:0016020(membrane);GO:0030030(cell projection organization);GO:0030041(actin filament polymerization);GO:0044782(cilium organization)","NA","NA","NA","tetratricopeptide repeat domain 17 [Source:HGNC Symbol;Acc:HGNC:25596]",{"v":0.142572,"d":"0.14"},{"v":0.290414,"d":"0.29"},{"v":0.127258,"d":"0.13"},{"v":0.105741,"d":"0.11"},{"v":0.132575,"d":"0.13"},{"v":0.127146,"d":"0.13"},{"v":1.53297470051606,"d":"1.53"},{"v":0.616333887641699,"d":"0.62"},1,1,"up","no"]
[158794,0,"chr5","-",43666766,43667232,"ENST00000481681",1,467,"ENSG00000224993","RPL29P12","NA","NA","NA","NA","ribosomal protein L29 pseudogene 12 [Source:HGNC Symbol;Acc:HGNC:36608]",{"v":0.088321,"d":"0.09"},{"v":0.108271,"d":"0.11"},{"v":0.035056,"d":"0.04"},{"v":0.216478,"d":"0.22"},{"v":0.352753,"d":"0.35"},{"v":0.091583,"d":"0.09"},{"v":0.35054947383076,"d":"0.35"},{"v":-1.51231002550638,"d":"-1.51"},1,1,"down","no"]
[203796,0,"chrX","-",63637982,63674138,"ENST00000466925",4,530,"ENSG00000131089","ARHGEF9","GO:0005085(guanyl-nucleotide exchange factor activity);GO:0005089(Rho guanyl-nucleotide exchange factor activity);GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0007186(G protein-coupled receptor signaling pathway);GO:0014069(postsynaptic density);GO:0016020(membrane);GO:0030054(cell junction);GO:0035023(regulation of Rho protein signal transduction);GO:0043065(positive regulation of apoptotic process);GO:0045202(synapse);GO:0045211(postsynaptic membrane);GO:0051056(regulation of small GTPase mediated signal transduction);GO:0098982(GABA-ergic synapse);GO:0099150(regulation of postsynaptic specialization assembly)","NA","K20686","NA","Cdc42 guanine nucleotide exchange factor 9 [Source:HGNC Symbol;Acc:HGNC:14561]",0,{"v":0.18035,"d":"0.18"},{"v":0.212651,"d":"0.21"},0,0,{"v":0.198568,"d":"0.20"},{"v":1.97917589943999,"d":"1.98"},{"v":0.984899837737902,"d":"0.98"},1,1,"up","no"]
[76897,0,"chr16","+",69187561,69260100,"ENST00000524887",4,537,"ENSG00000168807","SNTB2","GO:0003723(RNA binding);GO:0003779(actin binding);GO:0005198(structural molecule activity);GO:0005515(protein binding);GO:0005516(calmodulin binding);GO:0005737(cytoplasm);GO:0005856(cytoskeleton);GO:0005874(microtubule);GO:0005925(focal adhesion);GO:0016010(dystrophin-associated glycoprotein complex);GO:0016020(membrane);GO:0030054(cell junction);GO:0030658(transport vesicle membrane);GO:0031410(cytoplasmic vesicle);GO:0032991(protein-containing complex);GO:0045202(synapse)","NA","NA","NA","syntrophin beta 2 [Source:HGNC Symbol;Acc:HGNC:11169]",0,0,0,0,0,0,1,0,1,1,"no","no"]
[94664,0,"chr18","-",49482176,49491586,"ENST00000577910",8,1012,"ENSG00000215472","RPL17-C18orf32","GO:0002181(cytoplasmic translation);GO:0003735(structural constituent of ribosome);GO:0005622(intracellular);GO:0005840(ribosome);GO:0006412(translation);GO:0015934(large ribosomal subunit);GO:0022625(cytosolic large ribosomal subunit)","03010(Ribosome)","K02880","NA","RPL17-C18orf32 readthrough [Source:HGNC Symbol;Acc:HGNC:44661]",0,0,0,0,0,0,1,0,1,1,"no","no"]
[132788,0,"chr22","+",24270898,24442356,"ENST00000358654",20,6204,"ENSG00000258555","SPECC1L-ADORA2A","GO:0005815(microtubule organizing center);GO:0030036(actin cytoskeleton organization);GO:0031941(filamentous actin)","NA","NA","NA","SPECC1L-ADORA2A readthrough (NMD candidate) [Source:HGNC Symbol;Acc:HGNC:49185]",{"v":0.249759,"d":"0.25"},0,0,0,0,0,"inf","inf",1,1,"up","no"]
[154354,0,"chr4","-",117575098,117576109,"ENST00000394500",1,1012,"ENSG00000213492","NT5C3AP1","NA","NA","NA","NA","5'-nucleotidase, cytosolic IIIA pseudogene 1 [Source:HGNC Symbol;Acc:HGNC:18530]",{"v":0.140957,"d":"0.14"},{"v":0.107482,"d":"0.11"},{"v":0.441556,"d":"0.44"},{"v":0.144098,"d":"0.14"},{"v":0.664945,"d":"0.66"},{"v":0.457272,"d":"0.46"},{"v":0.5448841717898,"d":"0.54"},{"v":-0.875978511867999,"d":"-0.88"},1,1,"down","no"]
[157469,0,"chr5","+",7869184,7877965,"ENST00000503550",6,556,"ENSG00000124275","MTRR","GO:0000096(sulfur amino acid metabolic process);GO:0003958(NADPH-hemoprotein reductase activity);GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0006306(DNA methylation);GO:0006555(methionine metabolic process);GO:0008652(cellular amino acid biosynthetic process);GO:0009086(methionine biosynthetic process);GO:0009235(cobalamin metabolic process);GO:0010181(FMN binding);GO:0016491(oxidoreductase activity);GO:0016723(oxidoreductase activity, oxidizing metal ions, NAD or NADP as acceptor);GO:0030586([methionine synthase] reductase activity);GO:0032259(methylation);GO:0033353(S-adenosylmethionine cycle);GO:0043418(homocysteine catabolic process);GO:0046655(folic acid metabolic process);GO:0050444(aquacobalamin reductase (NADPH) activity);GO:0050660(flavin adenine dinucleotide binding);GO:0050661(NADP binding);GO:0050667(homocysteine metabolic process);GO:0055114(oxidation-reduction process);GO:0070402(NADPH binding);GO:0071949(FAD binding);GO:1904042(negative regulation of cystathionine beta-synthase activity)","NA","K00597","EC:1.16.1.8","5-methyltetrahydrofolate-homocysteine methyltransferase reductase [Source:HGNC Symbol;Acc:HGNC:7473]",0,0,{"v":0.029034,"d":"0.03"},{"v":0.711308,"d":"0.71"},{"v":1.147905,"d":"1.15"},{"v":1.302299,"d":"1.30"},{"v":0.00918358051463983,"d":"0.01"},{"v":-6.76672754021714,"d":"-6.77"},1,1,"down","no"]
[138625,0,"chr3","+",40529288,40532861,"ENST00000492098",3,1098,"ENSG00000172888","ZNF621","GO:0000981(DNA-binding transcription factor activity, RNA polymerase II-specific);GO:0003676(nucleic acid binding);GO:0003677(DNA binding);GO:0005622(intracellular);GO:0005634(nucleus);GO:0006355(regulation of transcription, DNA-templated);GO:0006357(regulation of transcription by RNA polymerase II);GO:0016607(nuclear speck);GO:0046872(metal ion binding)","05168(Herpes simplex virus 1 infection)","K09228","NA","zinc finger protein 621 [Source:HGNC Symbol;Acc:HGNC:24787]",{"v":0.004911,"d":"0.00"},{"v":0.220058,"d":"0.22"},{"v":0.023315,"d":"0.02"},{"v":0.00492,"d":"0.00"},{"v":0.016655,"d":"0.02"},{"v":0.006891,"d":"0.01"},{"v":8.72212463992131,"d":"8.72"},{"v":3.1246796068047,"d":"3.12"},1,1,"up","no"]
[105740,0,"chr19","-",47489754,47493640,"ENST00000593905",6,548,"ENSG00000105402","NAPA","GO:0000139(Golgi membrane);GO:0000149(SNARE binding);GO:0005483(soluble NSF attachment protein activity);GO:0005515(protein binding);GO:0005623(cell);GO:0005774(vacuolar membrane);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0006886(intracellular protein transport);GO:0006888(endoplasmic reticulum to Golgi vesicle-mediated transport);GO:0006890(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum);GO:0006891(intra-Golgi vesicle-mediated transport);GO:0007420(brain development);GO:0010807(regulation of synaptic vesicle priming);GO:0015031(protein transport);GO:0016020(membrane);GO:0016082(synaptic vesicle priming);GO:0016192(vesicle-mediated transport);GO:0019905(syntaxin binding);GO:0030182(neuron differentiation);GO:0031201(SNARE complex);GO:0032781(positive regulation of ATPase activity);GO:0032984(protein-containing complex disassembly);GO:0035249(synaptic transmission, glutamatergic);GO:0035494(SNARE complex disassembly);GO:0044877(protein-containing complex binding);GO:0045176(apical protein localization);GO:0048208(COPII vesicle coating);GO:0061025(membrane fusion);GO:0070044(synaptobrevin 2-SNAP-25-syntaxin-1a complex);GO:0070062(extracellular exosome);GO:0098793(presynapse);GO:0098794(postsynapse);GO:0098978(glutamatergic synapse)","04721(Synaptic vesicle cycle)","K15296","NA","NSF attachment protein alpha [Source:HGNC Symbol;Acc:HGNC:7641]",{"v":0.3577,"d":"0.36"},{"v":0.214812,"d":"0.21"},{"v":0.108631,"d":"0.11"},{"v":0.170732,"d":"0.17"},{"v":0.153128,"d":"0.15"},{"v":0.134448,"d":"0.13"},{"v":1.4862123288269,"d":"1.49"},{"v":0.57164024229834,"d":"0.57"},1,1,"up","no"]
[57339,0,"chr14","+",61485535,61529238,"ENST00000640011",2,286,"ENSG00000027075","PRKCH","GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0004697(protein kinase C activity);GO:0005515(protein binding);GO:0005524(ATP binding);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0006468(protein phosphorylation);GO:0007165(signal transduction);GO:0010744(positive regulation of macrophage derived foam cell differentiation);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0016740(transferase activity);GO:0018105(peptidyl-serine phosphorylation);GO:0019899(enzyme binding);GO:0030154(cell differentiation);GO:0030168(platelet activation);GO:0034351(negative regulation of glial cell apoptotic process);GO:0035556(intracellular signal transduction);GO:0045618(positive regulation of keratinocyte differentiation);GO:0046872(metal ion binding);GO:0050861(positive regulation of B cell receptor signaling pathway);GO:0051092(positive regulation of NF-kappaB transcription factor activity);GO:0060252(positive regulation of glial cell proliferation);GO:0070062(extracellular exosome);GO:1903078(positive regulation of protein localization to plasma membrane);GO:2000810(regulation of bicellular tight junction assembly)","04270(Vascular smooth muscle contraction);04750(Inflammatory mediator regulation of TRP channels)","NA","NA","protein kinase C eta [Source:HGNC Symbol;Acc:HGNC:9403]",{"v":0.118636,"d":"0.12"},{"v":0.117157,"d":"0.12"},{"v":0.058639,"d":"0.06"},{"v":2e-6,"d":"0.00"},{"v":0.207307,"d":"0.21"},{"v":0.594258,"d":"0.59"},{"v":0.367320510949178,"d":"0.37"},{"v":-1.44488863737354,"d":"-1.44"},1,1,"down","no"]
[152916,0,"chr4","-",86016478,86453360,"ENST00000638499",13,2565,"ENSG00000109339","MAPK10","GO:0000122(negative regulation of transcription by RNA polymerase II);GO:0000165(MAPK cascade);GO:0000166(nucleotide binding);GO:0000187(activation of MAPK activity);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0004705(JUN kinase activity);GO:0004707(MAP kinase activity);GO:0004708(MAP kinase kinase activity);GO:0005515(protein binding);GO:0005524(ATP binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0005739(mitochondrion);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0006468(protein phosphorylation);GO:0007165(signal transduction);GO:0007254(JNK cascade);GO:0007258(JUN phosphorylation);GO:0009414(response to water deprivation);GO:0009416(response to light stimulus);GO:0010468(regulation of gene expression);GO:0016020(membrane);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0016740(transferase activity);GO:0035556(intracellular signal transduction);GO:0038095(Fc-epsilon receptor signaling pathway);GO:0042752(regulation of circadian rhythm);GO:0043005(neuron projection);GO:0043204(perikaryon);GO:0048511(rhythmic process);GO:0051090(regulation of DNA-binding transcription factor activity);GO:0071310(cellular response to organic substance);GO:0071474(cellular hyperosmotic response);GO:0098969(neurotransmitter receptor transport to postsynaptic membrane);GO:0098978(glutamatergic synapse);GO:0099003(vesicle-mediated transport in synapse)","01522(Endocrine resistance);04010(MAPK signaling pathway);04012(ErbB signaling pathway);04014(Ras signaling pathway);04024(cAMP signaling pathway);04068(FoxO signaling pathway);04071(Sphingolipid signaling pathway);04137(Mitophagy - animal);04140(Autophagy - animal);04141(Protein processing in endoplasmic reticulum);04210(Apoptosis);04215(Apoptosis - multiple species);04217(Necroptosis);04310(Wnt signaling pathway);04380(Osteoclast differentiation);04510(Focal adhesion);04530(Tight junction);04620(Toll-like receptor signaling pathway);04621(NOD-like receptor signaling pathway);04622(RIG-I-like receptor signaling pathway);04625(C-type lectin receptor signaling pathway);04657(IL-17 signaling pathway);04658(Th1 and Th2 cell differentiation);04659(Th17 cell differentiation);04664(Fc epsilon RI signaling pathway);04668(TNF signaling pathway);04722(Neurotrophin signaling pathway);04723(Retrograde endocannabinoid signaling);04728(Dopaminergic synapse);04750(Inflammatory mediator regulation of TRP channels);04910(Insulin signaling pathway);04912(GnRH signaling pathway);04914(Progesterone-mediated oocyte maturation);04917(Prolactin signaling pathway);04920(Adipocytokine signaling pathway);04926(Relaxin signaling pathway);04930(Type II diabetes mellitus);04931(Insulin resistance);04932(Non-alcoholic fatty liver disease (NAFLD));04933(AGE-RAGE signaling pathway in diabetic complications);05120(Epithelial cell signaling in Helicobacter pylori infection);05131(Shigellosis);05132(Salmonella infection);05133(Pertussis);05142(Chagas disease (American trypanosomiasis));05145(Toxoplasmosis);05152(Tuberculosis);05161(Hepatitis B);05162(Measles);05164(Influenza A);05166(Human T-cell leukemia virus 1 infection);05167(Kaposi sarcoma-associated herpesvirus infection);05169(Epstein-Barr virus infection);05170(Human immunodeficiency virus 1 infection);05200(Pathways in cancer);05210(Colorectal cancer);05212(Pancreatic cancer);05231(Choline metabolism in cancer);05418(Fluid shear stress and atherosclerosis)","K04440","EC:2.7.11.24","mitogen-activated protein kinase 10 [Source:HGNC Symbol;Acc:HGNC:6872]",0,{"v":0.064049,"d":"0.06"},0,{"v":0.073199,"d":"0.07"},0,0,{"v":0.874998292326398,"d":"0.87"},{"v":-0.1926478935477,"d":"-0.19"},1,1,"down","no"]
[127146,0,"chr20","+",44903819,44905079,"ENST00000477896",2,410,"ENSG00000166913","YWHAB","GO:0000165(MAPK cascade);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005739(mitochondrion);GO:0005773(vacuole);GO:0005774(vacuolar membrane);GO:0005829(cytosol);GO:0005925(focal adhesion);GO:0006605(protein targeting);GO:0008022(protein C-terminus binding);GO:0016020(membrane);GO:0016032(viral process);GO:0017053(transcriptional repressor complex);GO:0019899(enzyme binding);GO:0019904(protein domain specific binding);GO:0032991(protein-containing complex);GO:0035308(negative regulation of protein dephosphorylation);GO:0035329(hippo signaling);GO:0042470(melanosome);GO:0042802(identical protein binding);GO:0042826(histone deacetylase binding);GO:0043085(positive regulation of catalytic activity);GO:0043488(regulation of mRNA stability);GO:0044877(protein-containing complex binding);GO:0045296(cadherin binding);GO:0045744(negative regulation of G protein-coupled receptor signaling pathway);GO:0045892(negative regulation of transcription, DNA-templated);GO:0048471(perinuclear region of cytoplasm);GO:0050815(phosphoserine residue binding);GO:0051219(phosphoprotein binding);GO:0051220(cytoplasmic sequestering of protein);GO:0051291(protein heterooligomerization);GO:0061024(membrane organization);GO:0070062(extracellular exosome);GO:1900740(positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway)","04110(Cell cycle);04114(Oocyte meiosis);04151(PI3K-Akt signaling pathway);04390(Hippo signaling pathway);05160(Hepatitis C);05161(Hepatitis B);05203(Viral carcinogenesis)","K16197","NA","tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta [Source:HGNC Symbol;Acc:HGNC:12849]",{"v":0.017179,"d":"0.02"},{"v":0.052126,"d":"0.05"},{"v":0.049585,"d":"0.05"},{"v":0.062522,"d":"0.06"},{"v":0.008857,"d":"0.01"},{"v":0.037049,"d":"0.04"},{"v":1.09648799203158,"d":"1.10"},{"v":0.132890012712508,"d":"0.13"},1,1,"up","no"]
[188437,0,"chr8","+",38386441,38408544,"ENST00000297720",10,1693,"ENSG00000165046","LETM2","GO:0005739(mitochondrion);GO:0005743(mitochondrial inner membrane);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0043022(ribosome binding)","NA","NA","NA","leucine zipper and EF-hand containing transmembrane protein 2 [Source:HGNC Symbol;Acc:HGNC:14648]",0,0,0,0,0,0,1,0,1,1,"no","no"]
[80279,0,"chr17","-",4960187,4967785,"ENST00000573805",3,495,"ENSG00000091640","SPAG7","GO:0003676(nucleic acid binding);GO:0005634(nucleus)","NA","NA","NA","sperm associated antigen 7 [Source:HGNC Symbol;Acc:HGNC:11216]",{"v":0.067067,"d":"0.07"},{"v":0.309968,"d":"0.31"},{"v":0.511845,"d":"0.51"},{"v":0.194298,"d":"0.19"},{"v":0.235095,"d":"0.24"},{"v":0.206466,"d":"0.21"},{"v":1.39791997911487,"d":"1.40"},{"v":0.483281779140884,"d":"0.48"},1,1,"up","no"]
[207146,0,"chrX","+",153794175,153796342,"ENST00000491833",3,921,"ENSG00000180879","SSR4","GO:0005783(endoplasmic reticulum);GO:0005784(Sec61 translocon complex);GO:0005789(endoplasmic reticulum membrane);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0070062(extracellular exosome)","04141(Protein processing in endoplasmic reticulum)","K04571","NA","signal sequence receptor subunit 4 [Source:HGNC Symbol;Acc:HGNC:11326]",{"v":0.169113,"d":"0.17"},{"v":0.002557,"d":"0.00"},{"v":0.001923,"d":"0.00"},0,{"v":0.000687,"d":"0.00"},{"v":0.003527,"d":"0.00"},{"v":41.1943521594684,"d":"41.19"},{"v":5.36437464904189,"d":"5.36"},1,1,"up","no"]
[68501,0,"chr15","+",93012428,93024742,"ENST00000627460",5,760,"ENSG00000173575","CHD2","GO:0000166(nucleotide binding);GO:0000978(RNA polymerase II proximal promoter sequence-specific DNA binding);GO:0003677(DNA binding);GO:0003723(RNA binding);GO:0004003(ATP-dependent DNA helicase activity);GO:0004386(helicase activity);GO:0005515(protein binding);GO:0005524(ATP binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005730(nucleolus);GO:0006325(chromatin organization);GO:0006357(regulation of transcription by RNA polymerase II);GO:0006974(cellular response to DNA damage stimulus);GO:0007517(muscle organ development);GO:0016787(hydrolase activity);GO:0032508(DNA duplex unwinding);GO:0042393(histone binding);GO:0043044(ATP-dependent chromatin remodeling);GO:0043231(intracellular membrane-bounded organelle);GO:0060218(hematopoietic stem cell differentiation)","NA","NA","NA","chromodomain helicase DNA binding protein 2 [Source:HGNC Symbol;Acc:HGNC:1917]",{"v":0.395592,"d":"0.40"},0,0,0,{"v":0.334925,"d":"0.33"},0,{"v":1.18113607524073,"d":"1.18"},{"v":0.240175182995955,"d":"0.24"},1,1,"up","no"]
[74878,0,"chr16","-",52552090,52554179,"ENST00000565755",2,461,"ENSG00000249231","CASC16","NA","NA","NA","NA","cancer susceptibility 16 [Source:HGNC Symbol;Acc:HGNC:48608]",{"v":0.071706,"d":"0.07"},0,0,0,0,0,"inf","inf",1,1,"up","no"]
[170704,0,"chr6","+",43059653,43067397,"ENST00000458460",6,1251,"ENSG00000137171","KLC4","GO:0003777(microtubule motor activity);GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0005856(cytoskeleton);GO:0005871(kinesin complex);GO:0005874(microtubule)","05132(Salmonella infection)","K10407","NA","kinesin light chain 4 [Source:HGNC Symbol;Acc:HGNC:21624]",{"v":0.03377,"d":"0.03"},{"v":0.05425,"d":"0.05"},{"v":0.047989,"d":"0.05"},0,{"v":0.150267,"d":"0.15"},{"v":0.014332,"d":"0.01"},{"v":0.826305141586522,"d":"0.83"},{"v":-0.275253450095794,"d":"-0.28"},1,1,"down","no"]
[153448,0,"chr4","-",98880765,98929092,"ENST00000280892",7,1097,"ENSG00000151247","EIF4E","GO:0000082(G1/S transition of mitotic cell cycle);GO:0000339(RNA cap binding);GO:0000340(RNA 7-methylguanosine cap binding);GO:0000932(P-body);GO:0001662(behavioral fear response);GO:0003723(RNA binding);GO:0003743(translation initiation factor activity);GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005845(mRNA cap binding complex);GO:0006405(RNA export from nucleus);GO:0006406(mRNA export from nucleus);GO:0006412(translation);GO:0006413(translational initiation);GO:0006417(regulation of translation);GO:0010494(cytoplasmic stress granule);GO:0016032(viral process);GO:0016281(eukaryotic translation initiation factor 4F complex);GO:0016442(RISC complex);GO:0017148(negative regulation of translation);GO:0019827(stem cell population maintenance);GO:0019899(enzyme binding);GO:0030324(lung development);GO:0031370(eukaryotic initiation factor 4G binding);GO:0032991(protein-containing complex);GO:0033391(chromatoid body);GO:0036464(cytoplasmic ribonucleoprotein granule);GO:0045182(translation regulator activity);GO:0045665(negative regulation of neuron differentiation);GO:0045931(positive regulation of mitotic cell cycle);GO:0048471(perinuclear region of cytoplasm);GO:0070062(extracellular exosome);GO:0070491(repressing transcription factor binding);GO:0071549(cellular response to dexamethasone stimulus);GO:0098794(postsynapse);GO:0098978(glutamatergic synapse);GO:0099524(postsynaptic cytosol);GO:0099578(regulation of translation at postsynapse, modulating synaptic transmission)","01521(EGFR tyrosine kinase inhibitor resistance);03013(RNA transport);04066(HIF-1 signaling pathway);04150(mTOR signaling pathway);04151(PI3K-Akt signaling pathway);04211(Longevity regulating pathway);04910(Insulin signaling pathway)","K03259","NA","eukaryotic translation initiation factor 4E [Source:HGNC Symbol;Acc:HGNC:3287]",{"v":0.019139,"d":"0.02"},{"v":0.020058,"d":"0.02"},0,{"v":0.36351,"d":"0.36"},0,0,{"v":0.107829220654177,"d":"0.11"},{"v":-3.21317990770269,"d":"-3.21"},1,1,"down","no"]
[178974,0,"chr7","+",50435380,50435486,"ENST00000363945",1,107,"ENSG00000200815","RNU6-1091P","NA","NA","NA","NA","RNA, U6 small nuclear 1091, pseudogene [Source:HGNC Symbol;Acc:HGNC:48054]",0,0,0,0,0,0,1,0,1,1,"no","no"]
[47119,0,"chr12","+",101719808,101719918,"ENST00000363063",1,111,"ENSG00000199933","RNY1P16","NA","NA","NA","NA","RNY1 pseudogene 16 [Source:HGNC Symbol;Acc:HGNC:50879]",0,{"v":0.281184,"d":"0.28"},{"v":0.219125,"d":"0.22"},0,0,{"v":0.144491,"d":"0.14"},{"v":3.46256168204248,"d":"3.46"},{"v":1.79183977154715,"d":"1.79"},1,1,"up","no"]
[87122,0,"chr17","-",48026171,48028560,"ENST00000585182",2,394,"ENSG00000005243","COPZ2","GO:0000139(Golgi membrane);GO:0005737(cytoplasm);GO:0005789(endoplasmic reticulum membrane);GO:0005794(Golgi apparatus);GO:0005801(cis-Golgi network);GO:0005829(cytosol);GO:0006886(intracellular protein transport);GO:0006888(endoplasmic reticulum to Golgi vesicle-mediated transport);GO:0006890(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum);GO:0006891(intra-Golgi vesicle-mediated transport);GO:0015031(protein transport);GO:0016020(membrane);GO:0016192(vesicle-mediated transport);GO:0030126(COPI vesicle coat);GO:0030133(transport vesicle);GO:0030663(COPI-coated vesicle membrane);GO:0031410(cytoplasmic vesicle);GO:0033116(endoplasmic reticulum-Golgi intermediate compartment membrane)","NA","K20472","NA","coatomer protein complex subunit zeta 2 [Source:HGNC Symbol;Acc:HGNC:19356]",{"v":0.001295,"d":"0.00"},{"v":0.553515,"d":"0.55"},{"v":0.406463,"d":"0.41"},{"v":0.170924,"d":"0.17"},{"v":0.334816,"d":"0.33"},{"v":0.203596,"d":"0.20"},{"v":1.3551730068684,"d":"1.36"},{"v":0.438477043622076,"d":"0.44"},1,1,"up","no"]
[197984,0,"chr9","-",100329186,100347304,"ENST00000429235",5,824,"ENSG00000136891","TEX10","GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005730(nucleolus);GO:0005737(cytoplasm);GO:0006364(rRNA processing);GO:0071339(MLL1 complex);GO:0097344(Rix1 complex)","NA","K14827","NA","testis expressed 10 [Source:HGNC Symbol;Acc:HGNC:25988]",{"v":0.592337,"d":"0.59"},{"v":0.953918,"d":"0.95"},0,{"v":0.496674,"d":"0.50"},{"v":0.799299,"d":"0.80"},0,{"v":1.19312285055321,"d":"1.19"},{"v":0.254742598572943,"d":"0.25"},1,1,"up","no"]
[101816,0,"chr19","-",23661935,23687220,"ENST00000599168",3,592,"ENSG00000197372","ZNF675","GO:0000122(negative regulation of transcription by RNA polymerase II);GO:0000981(DNA-binding transcription factor activity, RNA polymerase II-specific);GO:0003676(nucleic acid binding);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0005622(intracellular);GO:0005634(nucleus);GO:0006355(regulation of transcription, DNA-templated);GO:0007249(I-kappaB kinase/NF-kappaB signaling);GO:0008270(zinc ion binding);GO:0010804(negative regulation of tumor necrosis factor-mediated signaling pathway);GO:0019221(cytokine-mediated signaling pathway);GO:0031625(ubiquitin protein ligase binding);GO:0032088(negative regulation of NF-kappaB transcription factor activity);GO:0043508(negative regulation of JUN kinase activity);GO:0045453(bone resorption);GO:0045671(negative regulation of osteoclast differentiation);GO:0046329(negative regulation of JNK cascade);GO:0046872(metal ion binding);GO:0048471(perinuclear region of cytoplasm);GO:2000660(negative regulation of interleukin-1-mediated signaling pathway);GO:2000678(negative regulation of transcription regulatory region DNA binding)","05168(Herpes simplex virus 1 infection)","K09228","NA","zinc finger protein 675 [Source:HGNC Symbol;Acc:HGNC:30768]",{"v":0.446415,"d":"0.45"},{"v":0.001725,"d":"0.00"},{"v":0.12408,"d":"0.12"},{"v":0.026175,"d":"0.03"},{"v":0.139662,"d":"0.14"},{"v":0.212345,"d":"0.21"},{"v":1.51308100332644,"d":"1.51"},{"v":0.597489224811188,"d":"0.60"},1,1,"up","no"]
[24716,0,"chr10","+",119104095,119111928,"ENST00000493766",5,824,"ENSG00000119979","FAM45A","NA","NA","NA","NA","family with sequence similarity 45 member A [Source:HGNC Symbol;Acc:HGNC:31793]",0,0,{"v":0.346546,"d":"0.35"},0,{"v":0.302372,"d":"0.30"},{"v":0.104712,"d":"0.10"},{"v":0.851288677521101,"d":"0.85"},{"v":-0.232279652746196,"d":"-0.23"},1,1,"down","no"]
[44798,0,"chr12","+",57604623,57606511,"ENST00000550596",3,569,"ENSG00000178498","DTX3","GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0007219(Notch signaling pathway);GO:0016567(protein ubiquitination);GO:0016740(transferase activity);GO:0046872(metal ion binding)","04330(Notch signaling pathway)","K06058","EC:2.3.2.27","deltex E3 ubiquitin ligase 3 [Source:HGNC Symbol;Acc:HGNC:24457]",{"v":8.1e-5,"d":"0.00"},0,0,{"v":0.244836,"d":"0.24"},0,{"v":0.106196,"d":"0.11"},{"v":0.000230748193896853,"d":"0.00"},{"v":-12.0813930238398,"d":"-12.08"},1,1,"down","no"]
[56101,0,"chr14","-",39031919,39088723,"ENST00000537403",16,4215,"ENSG00000100934","SEC23A","GO:0000139(Golgi membrane);GO:0002474(antigen processing and presentation of peptide antigen via MHC class I);GO:0005096(GTPase activator activity);GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005829(cytosol);GO:0006886(intracellular protein transport);GO:0006888(endoplasmic reticulum to Golgi vesicle-mediated transport);GO:0008270(zinc ion binding);GO:0012507(ER to Golgi transport vesicle membrane);GO:0015031(protein transport);GO:0016020(membrane);GO:0016192(vesicle-mediated transport);GO:0019886(antigen processing and presentation of exogenous peptide antigen via MHC class II);GO:0019898(extrinsic component of membrane);GO:0030127(COPII vesicle coat);GO:0030134(COPII-coated ER to Golgi transport vesicle);GO:0031410(cytoplasmic vesicle);GO:0043547(positive regulation of GTPase activity);GO:0046872(metal ion binding);GO:0048208(COPII vesicle coating);GO:0048471(perinuclear region of cytoplasm);GO:0070971(endoplasmic reticulum exit site);GO:0072659(protein localization to plasma membrane);GO:0090110(COPII-coated vesicle cargo loading);GO:0090114(COPII-coated vesicle budding)","04141(Protein processing in endoplasmic reticulum)","K14006","NA","Sec23 homolog A, coat complex II component [Source:HGNC Symbol;Acc:HGNC:10701]",{"v":0.008295,"d":"0.01"},0,0,0,0,0,"inf","inf",1,1,"up","no"]
[58024,0,"chr14","-",70581257,70600643,"ENST00000554963",9,975,"ENSG00000133997","MED6","GO:0000151(ubiquitin ligase complex);GO:0003677(DNA binding);GO:0003712(transcription coregulator activity);GO:0003713(transcription coactivator activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0006357(regulation of transcription by RNA polymerase II);GO:0006367(transcription initiation from RNA polymerase II promoter);GO:0008134(transcription factor binding);GO:0016020(membrane);GO:0016567(protein ubiquitination);GO:0016592(mediator complex);GO:0019827(stem cell population maintenance);GO:0045944(positive regulation of transcription by RNA polymerase II);GO:0051123(RNA polymerase II preinitiation complex assembly);GO:0061630(ubiquitin protein ligase activity);GO:0070847(core mediator complex)","NA","K15128","NA","mediator complex subunit 6 [Source:HGNC Symbol;Acc:HGNC:19970]",{"v":0.337219,"d":"0.34"},{"v":0.330117,"d":"0.33"},0,{"v":0.253901,"d":"0.25"},{"v":0.259199,"d":"0.26"},{"v":0.285101,"d":"0.29"},{"v":0.836050067589492,"d":"0.84"},{"v":-0.258338752939841,"d":"-0.26"},1,1,"down","no"]
[130200,0,"chr21","+",36246301,36261915,"ENST00000463668",6,2178,"ENSG00000142197","DOP1B","GO:0000139(Golgi membrane);GO:0003674(molecular_function);GO:0005768(endosome);GO:0005794(Golgi apparatus);GO:0005802(trans-Golgi network);GO:0005829(cytosol);GO:0006895(Golgi to endosome transport);GO:0007029(endoplasmic reticulum organization);GO:0007275(multicellular organism development);GO:0015031(protein transport);GO:0016020(membrane);GO:0050890(cognition);GO:0070062(extracellular exosome)","NA","NA","NA","DOP1 leucine zipper like protein B [Source:HGNC Symbol;Acc:HGNC:1291]",{"v":0.093777,"d":"0.09"},{"v":0.042139,"d":"0.04"},{"v":0.081913,"d":"0.08"},{"v":0.068647,"d":"0.07"},{"v":0.072607,"d":"0.07"},{"v":0.073636,"d":"0.07"},{"v":1.01367676485644,"d":"1.01"},{"v":0.0195976877643644,"d":"0.02"},1,1,"up","no"]
[72761,0,"chr16","+",23678869,23681022,"ENST00000570220",3,910,"ENSG00000166851","PLK1","GO:0000070(mitotic sister chromatid segregation);GO:0000086(G2/M transition of mitotic cell cycle);GO:0000122(negative regulation of transcription by RNA polymerase II);GO:0000166(nucleotide binding);GO:0000278(mitotic cell cycle);GO:0000281(mitotic cytokinesis);GO:0000287(magnesium ion binding);GO:0000775(chromosome, centromeric region);GO:0000776(kinetochore);GO:0000777(condensed chromosome kinetochore);GO:0000780(condensed nuclear chromosome, centromeric region);GO:0000785(chromatin);GO:0000795(synaptonemal complex);GO:0000922(spindle pole);GO:0000942(condensed nuclear chromosome outer kinetochore);GO:0001578(microtubule bundle formation);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005515(protein binding);GO:0005524(ATP binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005694(chromosome);GO:0005737(cytoplasm);GO:0005813(centrosome);GO:0005814(centriole);GO:0005815(microtubule organizing center);GO:0005819(spindle);GO:0005829(cytosol);GO:0005856(cytoskeleton);GO:0005876(spindle microtubule);GO:0006468(protein phosphorylation);GO:0006511(ubiquitin-dependent protein catabolic process);GO:0007049(cell cycle);GO:0007062(sister chromatid cohesion);GO:0007077(mitotic nuclear envelope disassembly);GO:0007094(mitotic spindle assembly checkpoint);GO:0007098(centrosome cycle);GO:0007346(regulation of mitotic cell cycle);GO:0008017(microtubule binding);GO:0008283(cell population proliferation);GO:0010389(regulation of G2/M transition of mitotic cell cycle);GO:0010800(positive regulation of peptidyl-threonine phosphorylation);GO:0010997(anaphase-promoting complex binding);GO:0015630(microtubule cytoskeleton);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0016321(female meiosis chromosome segregation);GO:0016567(protein ubiquitination);GO:0016740(transferase activity);GO:0018105(peptidyl-serine phosphorylation);GO:0019901(protein kinase binding);GO:0030071(regulation of mitotic metaphase/anaphase transition);GO:0030496(midbody);GO:0031145(anaphase-promoting complex-dependent catabolic process);GO:0031648(protein destabilization);GO:0032436(positive regulation of proteasomal ubiquitin-dependent protein catabolic process);GO:0032465(regulation of cytokinesis);GO:0033365(protein localization to organelle);GO:0034451(centriolar satellite);GO:0042802(identical protein binding);GO:0043066(negative regulation of apoptotic process);GO:0043393(regulation of protein binding);GO:0045143(homologous chromosome segregation);GO:0045184(establishment of protein localization);GO:0045736(negative regulation of cyclin-dependent protein serine/threonine kinase activity);GO:0045862(positive regulation of proteolysis);GO:0051081(nuclear envelope disassembly);GO:0051233(spindle midzone);GO:0051301(cell division);GO:0051443(positive regulation of ubiquitin-protein transferase activity);GO:0051726(regulation of cell cycle);GO:0070194(synaptonemal complex disassembly);GO:0071168(protein localization to chromatin);GO:0072425(signal transduction involved in G2 DNA damage checkpoint);GO:0090435(protein localization to nuclear envelope);GO:0097711(ciliary basal body-plasma membrane docking);GO:1900182(positive regulation of protein localization to nucleus);GO:1901673(regulation of mitotic spindle assembly);GO:1901990(regulation of mitotic cell cycle phase transition);GO:1902749(regulation of cell cycle G2/M phase transition);GO:1904668(positive regulation of ubiquitin protein ligase activity)","04068(FoxO signaling pathway);04110(Cell cycle);04114(Oocyte meiosis);04914(Progesterone-mediated oocyte maturation)","K06631","EC:2.7.11.21","polo like kinase 1 [Source:HGNC Symbol;Acc:HGNC:9077]",0,0,0,0,0,0,1,0,1,1,"no","no"]
[169176,0,"chr6","-",31730581,31737318,"ENST00000375780",7,1560,"ENSG00000213719","CLIC1","GO:0005244(voltage-gated ion channel activity);GO:0005254(chloride channel activity);GO:0005515(protein binding);GO:0005615(extracellular space);GO:0005634(nucleus);GO:0005635(nuclear envelope);GO:0005737(cytoplasm);GO:0005739(mitochondrion);GO:0005886(plasma membrane);GO:0005903(brush border);GO:0006811(ion transport);GO:0006821(chloride transport);GO:0007165(signal transduction);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0031965(nuclear membrane);GO:0031982(vesicle);GO:0034220(ion transmembrane transport);GO:0034707(chloride channel complex);GO:0034765(regulation of ion transmembrane transport);GO:0045296(cadherin binding);GO:0045669(positive regulation of osteoblast differentiation);GO:0048471(perinuclear region of cytoplasm);GO:0051726(regulation of cell cycle);GO:0051881(regulation of mitochondrial membrane potential);GO:0070062(extracellular exosome);GO:0070527(platelet aggregation);GO:0072562(blood microparticle);GO:1902476(chloride transmembrane transport)","NA","K05021","NA","chloride intracellular channel 1 [Source:HGNC Symbol;Acc:HGNC:2062]",0,0,0,{"v":3.759127,"d":"3.76"},0,0,"-inf","-inf",1,1,"down","no"]
[86909,0,"chr17","-",47157060,47188936,"ENST00000528748",7,859,"ENSG00000004897","CDC27","GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005680(anaphase-promoting complex);GO:0005737(cytoplasm);GO:0005813(centrosome);GO:0005819(spindle);GO:0005829(cytosol);GO:0005876(spindle microtubule);GO:0006511(ubiquitin-dependent protein catabolic process);GO:0007091(metaphase/anaphase transition of mitotic cell cycle);GO:0008283(cell population proliferation);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016567(protein ubiquitination);GO:0019903(protein phosphatase binding);GO:0031145(anaphase-promoting complex-dependent catabolic process);GO:0051301(cell division);GO:0070979(protein K11-linked ubiquitination);GO:1901990(regulation of mitotic cell cycle phase transition)","04110(Cell cycle);04114(Oocyte meiosis);04120(Ubiquitin mediated proteolysis);04914(Progesterone-mediated oocyte maturation);05166(Human T-cell leukemia virus 1 infection)","NA","NA","cell division cycle 27 [Source:HGNC Symbol;Acc:HGNC:1728]",{"v":0.286628,"d":"0.29"},{"v":0.041579,"d":"0.04"},0,{"v":0.017706,"d":"0.02"},{"v":0.260496,"d":"0.26"},{"v":0.019586,"d":"0.02"},{"v":1.10214985157226,"d":"1.10"},{"v":0.140320390354239,"d":"0.14"},1,1,"up","no"]
[120642,0,"chr2","+",199659551,199660729,"ENST00000443084",1,1179,"ENSG00000213938","SEPHS1P6","NA","NA","NA","NA","selenophosphate synthetase 1 pseudogene 6 [Source:HGNC Symbol;Acc:HGNC:42168]",{"v":0.081713,"d":"0.08"},{"v":0.074653,"d":"0.07"},0,{"v":0.050588,"d":"0.05"},{"v":0.039476,"d":"0.04"},{"v":0.055214,"d":"0.06"},{"v":1.07632263660017,"d":"1.08"},{"v":0.106110602478585,"d":"0.11"},1,1,"up","no"]
[60094,0,"chr14","+",100065417,100085098,"ENST00000557023",2,507,"ENSG00000196405","EVL","GO:0003779(actin binding);GO:0005515(protein binding);GO:0005522(profilin binding);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005856(cytoskeleton);GO:0005925(focal adhesion);GO:0007015(actin filament organization);GO:0007166(cell surface receptor signaling pathway);GO:0007399(nervous system development);GO:0007411(axon guidance);GO:0008154(actin polymerization or depolymerization);GO:0009887(animal organ morphogenesis);GO:0010633(negative regulation of epithelial cell migration);GO:0016020(membrane);GO:0017124(SH3 domain binding);GO:0030027(lamellipodium);GO:0030838(positive regulation of actin filament polymerization);GO:0042995(cell projection);GO:0045010(actin nucleation);GO:0045335(phagocytic vesicle);GO:0051289(protein homotetramerization);GO:0051496(positive regulation of stress fiber assembly);GO:0071346(cellular response to interferon-gamma);GO:1900028(negative regulation of ruffle assembly)","NA","NA","NA","Enah/Vasp-like [Source:HGNC Symbol;Acc:HGNC:20234]",0,0,0,0,0,0,1,0,1,1,"no","no"]
[8262,0,"chr1","-",92247062,92271652,"ENST00000495852",10,891,"ENSG00000174842","GLMN","GO:0001570(vasculogenesis);GO:0001843(neural tube closure);GO:0005171(hepatocyte growth factor receptor binding);GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0031397(negative regulation of protein ubiquitination);GO:0031461(cullin-RING ubiquitin ligase complex);GO:0031462(Cul2-RING ubiquitin ligase complex);GO:0031463(Cul3-RING ubiquitin ligase complex);GO:0031464(Cul4A-RING E3 ubiquitin ligase complex);GO:0031625(ubiquitin protein ligase binding);GO:0032434(regulation of proteasomal ubiquitin-dependent protein catabolic process);GO:0040029(regulation of gene expression, epigenetic);GO:0042130(negative regulation of T cell proliferation);GO:0042327(positive regulation of phosphorylation);GO:0042692(muscle cell differentiation);GO:0045086(positive regulation of interleukin-2 biosynthetic process);GO:0050715(positive regulation of cytokine secretion);GO:0055105(ubiquitin-protein transferase inhibitor activity);GO:0072359(circulatory system development)","NA","NA","NA","glomulin, FKBP associated protein [Source:HGNC Symbol;Acc:HGNC:14373]",{"v":0.40308,"d":"0.40"},{"v":0.75888,"d":"0.76"},{"v":0.418948,"d":"0.42"},{"v":0.349411,"d":"0.35"},0,{"v":0.457492,"d":"0.46"},{"v":1.95922930017611,"d":"1.96"},{"v":0.970286254607975,"d":"0.97"},1,1,"up","no"]
[207678,0,"chrX","+",156022786,156023531,"ENST00000483079",2,658,"ENSG00000182484","WASH6P","NA","NA","NA","NA","WAS protein family homolog 6, pseudogene [Source:HGNC Symbol;Acc:HGNC:31685]",{"v":0.073723,"d":"0.07"},{"v":0.358033,"d":"0.36"},{"v":0.067906,"d":"0.07"},{"v":0.144025,"d":"0.14"},{"v":0.062014,"d":"0.06"},{"v":0.090204,"d":"0.09"},{"v":1.68666263844209,"d":"1.69"},{"v":0.75417143864118,"d":"0.75"},1,1,"up","no"]
[62311,0,"chr15","-",32446674,32446964,"ENST00000610974",1,291,"ENSG00000274076","RN7SL539P","NA","NA","NA","NA","RNA, 7SL, cytoplasmic 539, pseudogene [Source:HGNC Symbol;Acc:HGNC:46555]",0,0,{"v":0.025182,"d":"0.03"},0,0,0,"inf","inf",1,1,"up","no"]
[197180,0,"chr9","+",88535105,88575789,"ENST00000375855",3,1457,"ENSG00000130045","NXNL2","GO:0007600(sensory perception);GO:0007601(visual perception);GO:0007608(sensory perception of smell);GO:0045494(photoreceptor cell maintenance)","NA","K17609","EC:1.8.1.8","nucleoredoxin like 2 [Source:HGNC Symbol;Acc:HGNC:30482]",0,0,0,{"v":0.129868,"d":"0.13"},{"v":0.124113,"d":"0.12"},0,"-inf","-inf",1,1,"down","no"]
[19206,0,"chr10","+",13195086,13201872,"ENST00000481292",4,900,"ENSG00000065328","MCM10","GO:0000082(G1/S transition of mitotic cell cycle);GO:0003677(DNA binding);GO:0003688(DNA replication origin binding);GO:0003690(double-stranded DNA binding);GO:0003697(single-stranded DNA binding);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005730(nucleolus);GO:0006260(DNA replication);GO:0006270(DNA replication initiation);GO:0006974(cellular response to DNA damage stimulus);GO:0008283(cell population proliferation);GO:0019899(enzyme binding);GO:0031298(replication fork protection complex);GO:0042802(identical protein binding);GO:0046872(metal ion binding)","NA","K10736","NA","minichromosome maintenance 10 replication initiation factor [Source:HGNC Symbol;Acc:HGNC:18043]",0,0,{"v":0.201832,"d":"0.20"},{"v":0.066416,"d":"0.07"},{"v":0.126416,"d":"0.13"},0,{"v":1.04667275141055,"d":"1.05"},{"v":0.0658104454062385,"d":"0.07"},1,1,"up","no"]
[187006,0,"chr8","-",18056724,18084126,"ENST00000636494",13,1975,"ENSG00000104763","ASAH1","GO:0005576(extracellular region);GO:0005615(extracellular space);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005764(lysosome);GO:0006629(lipid metabolic process);GO:0006665(sphingolipid metabolic process);GO:0006687(glycosphingolipid metabolic process);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016787(hydrolase activity);GO:0016810(hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds);GO:0016811(hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides);GO:0017040(N-acylsphingosine amidohydrolase activity);GO:0030216(keratinocyte differentiation);GO:0043202(lysosomal lumen);GO:0043312(neutrophil degranulation);GO:0046512(sphingosine biosynthetic process);GO:0046513(ceramide biosynthetic process);GO:0046514(ceramide catabolic process);GO:0050810(regulation of steroid biosynthetic process);GO:0062098(regulation of programmed necrotic cell death);GO:0070062(extracellular exosome);GO:0071356(cellular response to tumor necrosis factor);GO:0102121(ceramidase activity);GO:1904724(tertiary granule lumen);GO:1904813(ficolin-1-rich granule lumen)","00600(Sphingolipid metabolism);04071(Sphingolipid signaling pathway);04142(Lysosome)","NA","NA","N-acylsphingosine amidohydrolase 1 [Source:HGNC Symbol;Acc:HGNC:735]",{"v":7.307055,"d":"7.31"},0,0,0,0,{"v":0.331689,"d":"0.33"},{"v":22.0298381918001,"d":"22.03"},{"v":4.46138699343298,"d":"4.46"},1,1,"up","no"]
[138955,0,"chr3","+",43717671,43734371,"ENST00000463153",3,628,"ENSG00000011198","ABHD5","GO:0003841(1-acylglycerol-3-phosphate O-acyltransferase activity);GO:0005737(cytoplasm);GO:0005811(lipid droplet);GO:0005829(cytosol);GO:0006508(proteolysis);GO:0006629(lipid metabolic process);GO:0006631(fatty acid metabolic process);GO:0006654(phosphatidic acid biosynthetic process);GO:0008233(peptidase activity);GO:0008654(phospholipid biosynthetic process);GO:0010891(negative regulation of sequestering of triglyceride);GO:0010898(positive regulation of triglyceride catabolic process);GO:0016740(transferase activity);GO:0016746(transferase activity, transferring acyl groups);GO:0016787(hydrolase activity);GO:0030154(cell differentiation);GO:0042171(lysophosphatidic acid acyltransferase activity);GO:0050996(positive regulation of lipid catabolic process);GO:0051006(positive regulation of lipoprotein lipase activity);GO:0052689(carboxylic ester hydrolase activity);GO:0055088(lipid homeostasis)","04923(Regulation of lipolysis in adipocytes)","K13699","EC:2.3.1.51","abhydrolase domain containing 5 [Source:HGNC Symbol;Acc:HGNC:21396]",0,{"v":0.547448,"d":"0.55"},0,{"v":0.090386,"d":"0.09"},0,0,{"v":6.05677870466665,"d":"6.06"},{"v":2.59855070088826,"d":"2.60"},1,1,"up","no"]
[73269,0,"chr16","+",28903373,28903826,"ENST00000564112",2,195,"ENSG00000196296","ATP2A1","GO:0000166(nucleotide binding);GO:0005388(calcium-transporting ATPase activity);GO:0005509(calcium ion binding);GO:0005515(protein binding);GO:0005524(ATP binding);GO:0005739(mitochondrion);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0006811(ion transport);GO:0006816(calcium ion transport);GO:0006874(cellular calcium ion homeostasis);GO:0008553(proton-exporting ATPase activity, phosphorylative mechanism);GO:0008637(apoptotic mitochondrial changes);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016529(sarcoplasmic reticulum);GO:0031095(platelet dense tubular network membrane);GO:0031448(positive regulation of fast-twitch skeletal muscle fiber contraction);GO:0032470(positive regulation of endoplasmic reticulum calcium ion concentration);GO:0032471(negative regulation of endoplasmic reticulum calcium ion concentration);GO:0033017(sarcoplasmic reticulum membrane);GO:0034220(ion transmembrane transport);GO:0034704(calcium channel complex);GO:0034976(response to endoplasmic reticulum stress);GO:0042803(protein homodimerization activity);GO:0046872(metal ion binding);GO:0051561(positive regulation of mitochondrial calcium ion concentration);GO:0051659(maintenance of mitochondrion location);GO:0070059(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress);GO:0070509(calcium ion import);GO:0070588(calcium ion transmembrane transport);GO:0090076(relaxation of skeletal muscle);GO:0099132(ATP hydrolysis coupled cation transmembrane transport);GO:1902600(proton transmembrane transport);GO:1903779(regulation of cardiac conduction)","04020(Calcium signaling pathway);04022(cGMP-PKG signaling pathway);04972(Pancreatic secretion);05010(Alzheimer disease)","NA","NA","ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1 [Source:HGNC Symbol;Acc:HGNC:811]",{"v":0.11231,"d":"0.11"},0,{"v":0.112739,"d":"0.11"},0,0,{"v":0.124413,"d":"0.12"},{"v":1.80888653115028,"d":"1.81"},{"v":0.855101912613085,"d":"0.86"},1,1,"up","no"]
[174899,0,"chr6","+",149852462,149853192,"ENST00000472053",2,312,"ENSG00000273132","AL355312","NA","NA","NA","NA","novel transcript, antisense to LRP11",0,0,0,0,0,0,1,0,1,1,"no","no"]
[58014,0,"chr14","-",70372488,70417061,"ENST00000554216",3,902,"ENSG00000213463","SYNJ2BP","GO:0001937(negative regulation of endothelial cell proliferation);GO:0005515(protein binding);GO:0005739(mitochondrion);GO:0005741(mitochondrial outer membrane);GO:0006605(protein targeting);GO:0007266(Rho protein signal transduction);GO:0007268(chemical synaptic transmission);GO:0008022(protein C-terminus binding);GO:0008328(ionotropic glutamate receptor complex);GO:0008593(regulation of Notch signaling pathway);GO:0010596(negative regulation of endothelial cell migration);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016323(basolateral plasma membrane);GO:0016525(negative regulation of angiogenesis);GO:0030054(cell junction);GO:0030100(regulation of endocytosis);GO:0031307(integral component of mitochondrial outer membrane);GO:0031594(neuromuscular junction);GO:0035255(ionotropic glutamate receptor binding);GO:0043005(neuron projection);GO:0043113(receptor clustering);GO:0045197(establishment or maintenance of epithelial cell apical/basal polarity);GO:0048312(intracellular distribution of mitochondria);GO:0070373(negative regulation of ERK1 and ERK2 cascade);GO:0097120(receptor localization to synapse);GO:0098609(cell-cell adhesion);GO:0098839(postsynaptic density membrane);GO:1903671(negative regulation of sprouting angiogenesis)","NA","K20057","NA","synaptojanin 2 binding protein [Source:HGNC Symbol;Acc:HGNC:18955]",{"v":0.350889,"d":"0.35"},{"v":0.492249,"d":"0.49"},{"v":0.192976,"d":"0.19"},{"v":0.224504,"d":"0.22"},{"v":0.574272,"d":"0.57"},{"v":0.365988,"d":"0.37"},{"v":0.88954844071417,"d":"0.89"},{"v":-0.168854924723467,"d":"-0.17"},1,1,"down","no"]
[142933,0,"chr3","-",113291533,113294456,"ENST00000484923",2,721,"ENSG00000206530","CFAP44","GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0005856(cytoskeleton);GO:0005929(cilium);GO:0007288(sperm axoneme assembly);GO:0030317(flagellated sperm motility);GO:0031514(motile cilium);GO:0042995(cell projection);GO:0060285(cilium-dependent cell motility)","NA","NA","NA","cilia and flagella associated protein 44 [Source:HGNC Symbol;Acc:HGNC:25631]",{"v":0.05829,"d":"0.06"},{"v":0.206314,"d":"0.21"},{"v":0.064106,"d":"0.06"},{"v":0.054289,"d":"0.05"},{"v":0.084157,"d":"0.08"},{"v":0.221404,"d":"0.22"},{"v":0.913463943309712,"d":"0.91"},{"v":-0.130580311666685,"d":"-0.13"},1,1,"down","no"]
[5576,0,"chr1","+",45012212,45013460,"ENST00000461035",4,486,"ENSG00000126088","UROD","GO:0004853(uroporphyrinogen decarboxylase activity);GO:0005515(protein binding);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0006779(porphyrin-containing compound biosynthetic process);GO:0006782(protoporphyrinogen IX biosynthetic process);GO:0006783(heme biosynthetic process);GO:0016829(lyase activity);GO:0016831(carboxy-lyase activity);GO:0042168(heme metabolic process)","00860(Porphyrin and chlorophyll metabolism)","K01599","EC:4.1.1.37","uroporphyrinogen decarboxylase [Source:HGNC Symbol;Acc:HGNC:12591]",{"v":0.126209,"d":"0.13"},{"v":0.124507,"d":"0.12"},{"v":0.069835,"d":"0.07"},{"v":0.255778,"d":"0.26"},{"v":0.002044,"d":"0.00"},{"v":0.114454,"d":"0.11"},{"v":0.861057387529682,"d":"0.86"},{"v":-0.215818701695618,"d":"-0.22"},1,1,"down","no"]
[23025,0,"chr10","-",92046692,92243246,"ENST00000412050",10,7664,"ENSG00000107864","CPEB3","GO:0000122(negative regulation of transcription by RNA polymerase II);GO:0000900(translation repressor activity, mRNA regulatory element binding);GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0003730(mRNA 3'-UTR binding);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005886(plasma membrane);GO:0006412(translation);GO:0006417(regulation of translation);GO:0007616(long-term memory);GO:0008135(translation factor activity, RNA binding);GO:0014069(postsynaptic density);GO:0016020(membrane);GO:0017148(negative regulation of translation);GO:0030014(CCR4-NOT complex);GO:0030054(cell junction);GO:0030425(dendrite);GO:0035613(RNA stem-loop binding);GO:0035925(mRNA 3'-UTR AU-rich region binding);GO:0042995(cell projection);GO:0043005(neuron projection);GO:0043022(ribosome binding);GO:0045182(translation regulator activity);GO:0045202(synapse);GO:0045211(postsynaptic membrane);GO:0045727(positive regulation of translation);GO:0048167(regulation of synaptic plasticity);GO:0060213(positive regulation of nuclear-transcribed mRNA poly(A) tail shortening);GO:0060998(regulation of dendritic spine development);GO:0060999(positive regulation of dendritic spine development);GO:0061158(3'-UTR-mediated mRNA destabilization);GO:0071230(cellular response to amino acid stimulus);GO:0097440(apical dendrite);GO:0098794(postsynapse);GO:1900153(positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay);GO:1900248(negative regulation of cytoplasmic translational elongation);GO:1900365(positive regulation of mRNA polyadenylation);GO:1990124(messenger ribonucleoprotein complex);GO:2000766(negative regulation of cytoplasmic translation)","04114(Oocyte meiosis);04914(Progesterone-mediated oocyte maturation)","K02602","NA","cytoplasmic polyadenylation element binding protein 3 [Source:HGNC Symbol;Acc:HGNC:21746]",{"v":0.008497,"d":"0.01"},{"v":0.016379,"d":"0.02"},{"v":0.002375,"d":"0.00"},0,{"v":0.007384,"d":"0.01"},{"v":0.008539,"d":"0.01"},{"v":1.71142372668467,"d":"1.71"},{"v":0.775196996942663,"d":"0.78"},1,1,"up","no"]
[47732,0,"chr12","-",109451404,109464895,"ENST00000538161",6,1030,"ENSG00000110906","KCTD10","GO:0004842(ubiquitin-protein transferase activity);GO:0005112(Notch binding);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0006511(ubiquitin-dependent protein catabolic process);GO:0016567(protein ubiquitination);GO:0031463(Cul3-RING ubiquitin ligase complex);GO:0043161(proteasome-mediated ubiquitin-dependent protein catabolic process);GO:0051260(protein homooligomerization)","NA","K15074","NA","potassium channel tetramerization domain containing 10 [Source:HGNC Symbol;Acc:HGNC:23236]",{"v":0.011421,"d":"0.01"},0,0,{"v":0.013318,"d":"0.01"},{"v":0.01411,"d":"0.01"},{"v":0.20705,"d":"0.21"},{"v":0.0487081943721799,"d":"0.05"},{"v":-4.35969168675618,"d":"-4.36"},1,1,"down","no"]
[49114,0,"chr12","+",122129180,122130005,"ENST00000535876",2,465,"ENSG00000175727","MLXIP","GO:0000977(RNA polymerase II regulatory region sequence-specific DNA binding);GO:0000981(DNA-binding transcription factor activity, RNA polymerase II-specific);GO:0001228(DNA-binding transcription activator activity, RNA polymerase II-specific);GO:0003677(DNA binding);GO:0003700(DNA-binding transcription factor activity);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005739(mitochondrion);GO:0005741(mitochondrial outer membrane);GO:0006355(regulation of transcription, DNA-templated);GO:0006357(regulation of transcription by RNA polymerase II);GO:0016020(membrane);GO:0045944(positive regulation of transcription by RNA polymerase II);GO:0046983(protein dimerization activity);GO:1900402(regulation of carbohydrate metabolic process by regulation of transcription from RNA polymerase II promoter)","04931(Insulin resistance);04932(Non-alcoholic fatty liver disease (NAFLD))","K09113","NA","MLX interacting protein [Source:HGNC Symbol;Acc:HGNC:17055]",{"v":0.01881,"d":"0.02"},{"v":0.047505,"d":"0.05"},{"v":1.2e-5,"d":"0.00"},{"v":0.021151,"d":"0.02"},{"v":0.021616,"d":"0.02"},{"v":0.015932,"d":"0.02"},{"v":1.12995110649244,"d":"1.13"},{"v":0.176260347908626,"d":"0.18"},1,1,"up","no"]
[96412,0,"chr19","+",984378,998438,"ENST00000591997",4,577,"ENSG00000065268","WDR18","GO:0000027(ribosomal large subunit assembly);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005656(nuclear pre-replicative complex);GO:0005730(nucleolus);GO:0005737(cytoplasm);GO:0006267(pre-replicative complex assembly involved in nuclear cell cycle DNA replication);GO:0006364(rRNA processing);GO:0007275(multicellular organism development);GO:0030174(regulation of DNA-dependent DNA replication initiation);GO:0097344(Rix1 complex)","NA","K14829","NA","WD repeat domain 18 [Source:HGNC Symbol;Acc:HGNC:17956]",{"v":0.048669,"d":"0.05"},{"v":0.031477,"d":"0.03"},{"v":0.025401,"d":"0.03"},0,0,0,"inf","inf",1,1,"up","no"]
[81206,0,"chr17","+",7933117,7939703,"ENST00000571540",8,1209,"ENSG00000170037","CNTROB","GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0005813(centrosome);GO:0005814(centriole);GO:0005829(cytosol);GO:0005856(cytoskeleton);GO:0007049(cell cycle);GO:0007099(centriole replication);GO:0019904(protein domain specific binding);GO:0051299(centrosome separation);GO:0051301(cell division);GO:1902017(regulation of cilium assembly);GO:1902410(mitotic cytokinetic process)","NA","K16468","NA","centrobin, centriole duplication and spindle assembly protein [Source:HGNC Symbol;Acc:HGNC:29616]",{"v":0.51657,"d":"0.52"},{"v":0.354362,"d":"0.35"},{"v":0.370933,"d":"0.37"},{"v":0.484801,"d":"0.48"},{"v":0.581859,"d":"0.58"},{"v":0.039069,"d":"0.04"},{"v":1.12311877503439,"d":"1.12"},{"v":0.167510507517606,"d":"0.17"},1,1,"up","no"]
[200310,0,"chr9","+",133459965,133470787,"ENST00000542192",5,2754,"ENSG00000160325","CACFD1","GO:0003674(molecular_function);GO:0005515(protein binding);GO:0005575(cellular_component);GO:0008150(biological_process);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016192(vesicle-mediated transport)","NA","NA","NA","calcium channel flower domain containing 1 [Source:HGNC Symbol;Acc:HGNC:1365]",0,0,{"v":0.01358,"d":"0.01"},0,0,0,"inf","inf",1,1,"up","no"]
[137447,0,"chr3","-",18410798,18417393,"ENST00000491519",4,1000,"ENSG00000182568","SATB1","GO:0000122(negative regulation of transcription by RNA polymerase II);GO:0000785(chromatin);GO:0000977(RNA polymerase II regulatory region sequence-specific DNA binding);GO:0000981(DNA-binding transcription factor activity, RNA polymerase II-specific);GO:0001227(DNA-binding transcription repressor activity, RNA polymerase II-specific);GO:0003677(DNA binding);GO:0003682(chromatin binding);GO:0003690(double-stranded DNA binding);GO:0003700(DNA-binding transcription factor activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005720(nuclear heterochromatin);GO:0006325(chromatin organization);GO:0006338(chromatin remodeling);GO:0006355(regulation of transcription, DNA-templated);GO:0008544(epidermis development);GO:0016032(viral process);GO:0016363(nuclear matrix);GO:0016571(histone methylation);GO:0016604(nuclear body);GO:0016605(PML body);GO:0042110(T cell activation);GO:0043367(CD4-positive, alpha-beta T cell differentiation);GO:0043374(CD8-positive, alpha-beta T cell differentiation);GO:0043565(sequence-specific DNA binding);GO:0050798(activated T cell proliferation);GO:0060004(reflex)","NA","K23225","NA","SATB homeobox 1 [Source:HGNC Symbol;Acc:HGNC:10541]",0,0,{"v":0.028971,"d":"0.03"},{"v":0.029762,"d":"0.03"},0,{"v":0.031462,"d":"0.03"},{"v":0.473196785574285,"d":"0.47"},{"v":-1.07948782140364,"d":"-1.08"},1,1,"down","no"]
[102958,0,"chr19","-",36496916,36498159,"ENST00000593270",1,1244,"ENSG00000267091","CTBP2P7","NA","NA","NA","NA","C-terminal binding protein 2 pseudogene 7 [Source:HGNC Symbol;Acc:HGNC:45199]",0,0,{"v":0.099641,"d":"0.10"},0,0,{"v":0.06598,"d":"0.07"},{"v":1.51016974840861,"d":"1.51"},{"v":0.594710722678328,"d":"0.59"},1,1,"up","no"]
[24132,0,"chr10","+",104285938,104299418,"ENST00000467629",4,576,"ENSG00000065621","GSTO2","GO:0004364(glutathione transferase activity);GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0006805(xenobiotic metabolic process);GO:0016491(oxidoreductase activity);GO:0016740(transferase activity);GO:0019852(L-ascorbic acid metabolic process);GO:0042802(identical protein binding);GO:0045174(glutathione dehydrogenase (ascorbate) activity);GO:0050610(methylarsonate reductase activity);GO:0055114(oxidation-reduction process);GO:0070062(extracellular exosome);GO:0071243(cellular response to arsenic-containing substance);GO:0098869(cellular oxidant detoxification);GO:1901687(glutathione derivative biosynthetic process)","00480(Glutathione metabolism);00980(Metabolism of xenobiotics by cytochrome P450);00982(Drug metabolism - cytochrome P450);00983(Drug metabolism - other enzymes);01524(Platinum drug resistance);05200(Pathways in cancer);05204(Chemical carcinogenesis);05225(Hepatocellular carcinoma);05418(Fluid shear stress and atherosclerosis)","K00799","EC:2.5.1.18","glutathione S-transferase omega 2 [Source:HGNC Symbol;Acc:HGNC:23064]",{"v":0.022749,"d":"0.02"},0,{"v":0.01976,"d":"0.02"},0,0,0,"inf","inf",1,1,"up","no"]
[42856,0,"chr12","-",50979401,50992209,"ENST00000551215",6,609,"ENSG00000110911","SLC11A2","GO:0001666(response to hypoxia);GO:0005375(copper ion transmembrane transporter activity);GO:0005381(iron ion transmembrane transporter activity);GO:0005384(manganese ion transmembrane transporter activity);GO:0005506(iron ion binding);GO:0005507(copper ion binding);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005739(mitochondrion);GO:0005741(mitochondrial outer membrane);GO:0005765(lysosomal membrane);GO:0005768(endosome);GO:0005769(early endosome);GO:0005773(vacuole);GO:0005886(plasma membrane);GO:0005887(integral component of plasma membrane);GO:0006778(porphyrin-containing compound metabolic process);GO:0006779(porphyrin-containing compound biosynthetic process);GO:0006783(heme biosynthetic process);GO:0006811(ion transport);GO:0006824(cobalt ion transport);GO:0006825(copper ion transport);GO:0006826(iron ion transport);GO:0006828(manganese ion transport);GO:0006879(cellular iron ion homeostasis);GO:0007611(learning or memory);GO:0008270(zinc ion binding);GO:0009986(cell surface);GO:0010008(endosome membrane);GO:0010039(response to iron ion);GO:0015086(cadmium ion transmembrane transporter activity);GO:0015087(cobalt ion transmembrane transporter activity);GO:0015093(ferrous iron transmembrane transporter activity);GO:0015094(lead ion transmembrane transporter activity);GO:0015099(nickel cation transmembrane transporter activity);GO:0015295(solute:proton symporter activity);GO:0015692(lead ion transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016151(nickel cation binding);GO:0016324(apical plasma membrane);GO:0030001(metal ion transport);GO:0030145(manganese ion binding);GO:0031410(cytoplasmic vesicle);GO:0031526(brush border membrane);GO:0031902(late endosome membrane);GO:0033212(iron import into cell);GO:0034755(iron ion transmembrane transport);GO:0035434(copper ion transmembrane transport);GO:0035444(nickel cation transmembrane transport);GO:0045177(apical part of cell);GO:0045178(basal part of cell);GO:0046870(cadmium ion binding);GO:0046873(metal ion transmembrane transporter activity);GO:0046915(transition metal ion transmembrane transporter activity);GO:0048471(perinuclear region of cytoplasm);GO:0048813(dendrite morphogenesis);GO:0048821(erythrocyte development);GO:0050897(cobalt ion binding);GO:0055037(recycling endosome);GO:0055072(iron ion homeostasis);GO:0060586(multicellular organismal iron ion homeostasis);GO:0070574(cadmium ion transmembrane transport);GO:0070826(paraferritin complex);GO:0071421(manganese ion transmembrane transport);GO:1902600(proton transmembrane transport);GO:1903561(extracellular vesicle)","04142(Lysosome);04216(Ferroptosis);04978(Mineral absorption)","K21398","NA","solute carrier family 11 member 2 [Source:HGNC Symbol;Acc:HGNC:10908]",{"v":0.079908,"d":"0.08"},{"v":0.264618,"d":"0.26"},{"v":0.317907,"d":"0.32"},0,{"v":0.01352,"d":"0.01"},0,{"v":48.9965236686391,"d":"49.00"},{"v":5.61460748770849,"d":"5.61"},1,1,"up","no"]
[18334,0,"chr1","+",247294835,247294941,"ENST00000365209",1,107,"ENSG00000202079","RF00019","NA","NA","NA","NA","NA",0,{"v":0.191061,"d":"0.19"},0,0,0,{"v":0.599572,"d":"0.60"},{"v":0.318662312449547,"d":"0.32"},{"v":-1.64989969032204,"d":"-1.65"},1,1,"down","no"]
[142113,0,"chr3","+",94063061,94084176,"ENST00000468555",4,571,"ENSG00000178694","NSUN3","GO:0000049(tRNA binding);GO:0002127(tRNA wobble base cytosine methylation);GO:0003723(RNA binding);GO:0005739(mitochondrion);GO:0005759(mitochondrial matrix);GO:0005762(mitochondrial large ribosomal subunit);GO:0008168(methyltransferase activity);GO:0016428(tRNA (cytosine-5-)-methyltransferase activity);GO:0016740(transferase activity);GO:0031167(rRNA methylation);GO:0032259(methylation);GO:0070129(regulation of mitochondrial translation)","NA","K21969","EC:2.1.1.-","NOP2/Sun RNA methyltransferase family member 3 [Source:HGNC Symbol;Acc:HGNC:26208]",0,0,0,0,0,{"v":0.20047,"d":"0.20"},"-inf","-inf",1,1,"down","no"]
[39066,0,"chr12","+",6461035,6462298,"ENST00000544289",2,621,"ENSG00000139192","TAPBPL","GO:0000139(Golgi membrane);GO:0002376(immune system process);GO:0002502(peptide antigen assembly with MHC class I protein complex);GO:0002590(negative regulation of antigen processing and presentation of peptide antigen via MHC class I);GO:0005515(protein binding);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005794(Golgi apparatus);GO:0005886(plasma membrane);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0023024(MHC class I protein complex binding);GO:0031090(organelle membrane);GO:0043231(intracellular membrane-bounded organelle);GO:0044877(protein-containing complex binding)","NA","NA","NA","TAP binding protein like [Source:HGNC Symbol;Acc:HGNC:30683]",{"v":0.543606,"d":"0.54"},{"v":0.525888,"d":"0.53"},{"v":0.553462,"d":"0.55"},{"v":0.328303,"d":"0.33"},{"v":0.175309,"d":"0.18"},{"v":0.354703,"d":"0.35"},{"v":1.89086291163501,"d":"1.89"},{"v":0.919044771075292,"d":"0.92"},1,1,"up","no"]
[205199,0,"chrX","+",103776850,103792619,"ENST00000619236",7,2896,"ENSG00000123560","PLP1","GO:0005198(structural molecule activity);GO:0005515(protein binding);GO:0005886(plasma membrane);GO:0006954(inflammatory response);GO:0007229(integrin-mediated signaling pathway);GO:0007268(chemical synaptic transmission);GO:0008366(axon ensheathment);GO:0010001(glial cell differentiation);GO:0010628(positive regulation of gene expression);GO:0014002(astrocyte development);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0019911(structural constituent of myelin sheath);GO:0021762(substantia nigra development);GO:0022010(central nervous system myelination);GO:0031175(neuron projection development);GO:0042552(myelination);GO:0042759(long-chain fatty acid biosynthetic process);GO:0043209(myelin sheath);GO:0061564(axon development)","NA","K17271","NA","proteolipid protein 1 [Source:HGNC Symbol;Acc:HGNC:9086]",{"v":0.066429,"d":"0.07"},{"v":0.082462,"d":"0.08"},{"v":0.106466,"d":"0.11"},0,0,0,"inf","inf",1,1,"up","no"]
[36077,0,"chr11","-",110258114,110264824,"ENST00000642511",4,501,"ENSG00000137710","RDX","GO:0001726(ruffle);GO:0003723(RNA binding);GO:0003779(actin binding);GO:0005515(protein binding);GO:0005615(extracellular space);GO:0005737(cytoplasm);GO:0005856(cytoskeleton);GO:0005886(plasma membrane);GO:0005902(microvillus);GO:0005913(cell-cell adherens junction);GO:0005925(focal adhesion);GO:0008092(cytoskeletal protein binding);GO:0008360(regulation of cell shape);GO:0008361(regulation of cell size);GO:0010628(positive regulation of gene expression);GO:0010737(protein kinase A signaling);GO:0016020(membrane);GO:0016324(apical plasma membrane);GO:0019904(protein domain specific binding);GO:0030027(lamellipodium);GO:0030033(microvillus assembly);GO:0030175(filopodium);GO:0030315(T-tubule);GO:0030335(positive regulation of cell migration);GO:0030496(midbody);GO:0030864(cortical actin cytoskeleton);GO:0032154(cleavage furrow);GO:0032231(regulation of actin filament bundle assembly);GO:0032420(stereocilium);GO:0032487(regulation of Rap protein signal transduction);GO:0034111(negative regulation of homotypic cell-cell adhesion);GO:0034260(negative regulation of GTPase activity);GO:0036120(cellular response to platelet-derived growth factor stimulus);GO:0042803(protein homodimerization activity);GO:0042995(cell projection);GO:0043087(regulation of GTPase activity);GO:0045176(apical protein localization);GO:0045177(apical part of cell);GO:0045184(establishment of protein localization);GO:0045296(cadherin binding);GO:0045792(negative regulation of cell size);GO:0051016(barbed-end actin filament capping);GO:0051018(protein kinase A binding);GO:0051117(ATPase binding);GO:0051286(cell tip);GO:0051693(actin filament capping);GO:0061028(establishment of endothelial barrier);GO:0070062(extracellular exosome);GO:0071944(cell periphery);GO:0072659(protein localization to plasma membrane);GO:0097067(cellular response to thyroid hormone stimulus);GO:1900027(regulation of ruffle assembly);GO:1900087(positive regulation of G1/S transition of mitotic cell cycle);GO:1902115(regulation of organelle assembly);GO:1902966(positive regulation of protein localization to early endosome);GO:1903364(positive regulation of cellular protein catabolic process);GO:1903392(negative regulation of adherens junction organization);GO:2000643(positive regulation of early endosome to late endosome transport)","04530(Tight junction);04810(Regulation of actin cytoskeleton);05205(Proteoglycans in cancer);05206(MicroRNAs in cancer)","K05762","NA","radixin [Source:HGNC Symbol;Acc:HGNC:9944]",0,0,{"v":0.07411,"d":"0.07"},0,0,0,"inf","inf",1,1,"up","no"]
[57708,0,"chr14","+",67241435,67272059,"ENST00000554208",2,2458,"ENSG00000072415","MPP5","GO:0002011(morphogenesis of an epithelial sheet);GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0005886(plasma membrane);GO:0005913(cell-cell adherens junction);GO:0005923(bicellular tight junction);GO:0007009(plasma membrane organization);GO:0012505(endomembrane system);GO:0016020(membrane);GO:0019904(protein domain specific binding);GO:0030054(cell junction);GO:0032287(peripheral nervous system myelin maintenance);GO:0032288(myelin assembly);GO:0032991(protein-containing complex);GO:0035749(myelin sheath adaxonal region);GO:0035750(protein localization to myelin sheath abaxonal region);GO:0043219(lateral loop);GO:0043220(Schmidt-Lanterman incisure);GO:0070062(extracellular exosome);GO:0070830(bicellular tight junction assembly);GO:0072659(protein localization to plasma membrane);GO:0090162(establishment of epithelial cell polarity)","04390(Hippo signaling pathway);04530(Tight junction);05165(Human papillomavirus infection)","K06091","NA","membrane palmitoylated protein 5 [Source:HGNC Symbol;Acc:HGNC:18669]",{"v":0.007108,"d":"0.01"},{"v":0.006543,"d":"0.01"},{"v":0.019439,"d":"0.02"},{"v":0.020865,"d":"0.02"},{"v":0.000552,"d":"0.00"},{"v":0.001841,"d":"0.00"},{"v":1.4227362627913,"d":"1.42"},{"v":0.508668249617408,"d":"0.51"},1,1,"up","no"]
[207332,0,"chrX","-",154352553,154353598,"ENST00000415241",5,704,"ENSG00000196924","FLNA","GO:0001664(G protein-coupled receptor binding);GO:0002576(platelet degranulation);GO:0003723(RNA binding);GO:0003779(actin binding);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0005634(nucleus);GO:0005730(nucleolus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005856(cytoskeleton);GO:0005884(actin filament);GO:0005886(plasma membrane);GO:0005911(cell-cell junction);GO:0005925(focal adhesion);GO:0005938(cell cortex);GO:0007195(adenylate cyclase-inhibiting dopamine receptor signaling pathway);GO:0008134(transcription factor binding);GO:0015459(potassium channel regulator activity);GO:0015629(actin cytoskeleton);GO:0016020(membrane);GO:0016479(negative regulation of transcription by RNA polymerase I);GO:0017048(Rho GTPase binding);GO:0017160(Ral GTPase binding);GO:0019900(kinase binding);GO:0021943(formation of radial glial scaffolds);GO:0021987(cerebral cortex development);GO:0030018(Z disc);GO:0030030(cell projection organization);GO:0030168(platelet activation);GO:0030334(regulation of cell migration);GO:0030863(cortical cytoskeleton);GO:0031267(small GTPase binding);GO:0031523(Myb complex);GO:0031532(actin cytoskeleton reorganization);GO:0031852(mu-type opioid receptor binding);GO:0031941(filamentous actin);GO:0032233(positive regulation of actin filament bundle assembly);GO:0034329(cell junction assembly);GO:0034394(protein localization to cell surface);GO:0034988(Fc-gamma receptor I complex binding);GO:0042177(negative regulation of protein catabolic process);GO:0042307(positive regulation of protein import into nucleus);GO:0042789(mRNA transcription by RNA polymerase II);GO:0042803(protein homodimerization activity);GO:0043025(neuronal cell body);GO:0043066(negative regulation of apoptotic process);GO:0043113(receptor clustering);GO:0043123(positive regulation of I-kappaB kinase/NF-kappaB signaling);GO:0043198(dendritic shaft);GO:0043433(negative regulation of DNA-binding transcription factor activity);GO:0044319(wound healing, spreading of cells);GO:0044325(ion channel binding);GO:0044877(protein-containing complex binding);GO:0045184(establishment of protein localization);GO:0045296(cadherin binding);GO:0046332(SMAD binding);GO:0048365(Rac GTPase binding);GO:0048471(perinuclear region of cytoplasm);GO:0050821(protein stabilization);GO:0051015(actin filament binding);GO:0051020(GTPase binding);GO:0051220(cytoplasmic sequestering of protein);GO:0051607(defense response to virus);GO:0051764(actin crosslink formation);GO:0060271(cilium assembly);GO:0070062(extracellular exosome);GO:0070527(platelet aggregation);GO:0071526(semaphorin-plexin signaling pathway);GO:0072659(protein localization to plasma membrane);GO:0090307(mitotic spindle assembly);GO:0097368(establishment of Sertoli cell barrier);GO:0097440(apical dendrite);GO:0098794(postsynapse);GO:0098978(glutamatergic synapse);GO:1900026(positive regulation of substrate adhesion-dependent cell spreading);GO:1901381(positive regulation of potassium ion transmembrane transport);GO:1902396(protein localization to bicellular tight junction);GO:1905000(regulation of membrane repolarization during atrial cardiac muscle cell action potential);GO:1905031(regulation of membrane repolarization during cardiac muscle cell action potential);GO:2000179(positive regulation of neural precursor cell proliferation);GO:2001046(positive regulation of integrin-mediated signaling pathway);GO:2001224(positive regulation of neuron migration)","04010(MAPK signaling pathway);04510(Focal adhesion);05132(Salmonella infection);05205(Proteoglycans in cancer)","NA","NA","filamin A [Source:HGNC Symbol;Acc:HGNC:3754]",{"v":0.013354,"d":"0.01"},{"v":0.007675,"d":"0.01"},{"v":0.087812,"d":"0.09"},{"v":0.008754,"d":"0.01"},0,{"v":0.181889,"d":"0.18"},{"v":0.570915270951464,"d":"0.57"},{"v":-0.808651442553754,"d":"-0.81"},1,1,"down","no"]
[45060,0,"chr12","+",62260364,62355386,"ENST00000550632",6,728,"ENSG00000135655","USP15","GO:0003824(catalytic activity);GO:0004197(cysteine-type endopeptidase activity);GO:0004843(thiol-dependent ubiquitin-specific protease activity);GO:0005160(transforming growth factor beta receptor binding);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005739(mitochondrion);GO:0005829(cytosol);GO:0006508(proteolysis);GO:0006511(ubiquitin-dependent protein catabolic process);GO:0007179(transforming growth factor beta receptor signaling pathway);GO:0008233(peptidase activity);GO:0008234(cysteine-type peptidase activity);GO:0016579(protein deubiquitination);GO:0016787(hydrolase activity);GO:0030509(BMP signaling pathway);GO:0035520(monoubiquitinated protein deubiquitination);GO:0035616(histone H2B conserved C-terminal lysine deubiquitination);GO:0036459(thiol-dependent ubiquitinyl hydrolase activity);GO:0042802(identical protein binding);GO:0046332(SMAD binding);GO:0060389(pathway-restricted SMAD protein phosphorylation);GO:0061649(ubiquitin modification-dependent histone binding)","04137(Mitophagy - animal)","K21343","EC:3.4.19.12","ubiquitin specific peptidase 15 [Source:HGNC Symbol;Acc:HGNC:12613]",0,0,{"v":0.017597,"d":"0.02"},0,0,0,"inf","inf",1,1,"up","no"]
[155356,0,"chr4","-",145876496,145885748,"ENST00000513840",2,434,"ENSG00000151612","ZNF827","GO:0000979(RNA polymerase II core promoter sequence-specific DNA binding);GO:0003676(nucleic acid binding);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0005634(nucleus);GO:0010468(regulation of gene expression);GO:0035097(histone methyltransferase complex);GO:0046872(metal ion binding)","NA","NA","NA","zinc finger protein 827 [Source:HGNC Symbol;Acc:HGNC:27193]",0,0,0,0,0,0,1,0,1,1,"no","no"]
[165826,0,"chr5","+",177022696,177065241,"ENST00000506693",4,1276,"ENSG00000113761","ZNF346","GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0003725(double-stranded RNA binding);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005730(nucleolus);GO:0005737(cytoplasm);GO:0008270(zinc ion binding);GO:0019899(enzyme binding);GO:0035198(miRNA binding);GO:0043065(positive regulation of apoptotic process);GO:0046872(metal ion binding)","NA","NA","NA","zinc finger protein 346 [Source:HGNC Symbol;Acc:HGNC:16403]",0,0,{"v":0.052014,"d":"0.05"},{"v":0.18598,"d":"0.19"},0,0,{"v":0.279675233896118,"d":"0.28"},{"v":-1.8381755905091,"d":"-1.84"},1,1,"down","no"]
[5187,0,"chr1","-",43453161,43453808,"ENST00000469587",2,551,"ENSG00000178922","HYI","GO:0003674(molecular_function);GO:0005515(protein binding);GO:0005575(cellular_component);GO:0008150(biological_process);GO:0008903(hydroxypyruvate isomerase activity);GO:0016853(isomerase activity);GO:0016857(racemase and epimerase activity, acting on carbohydrates and derivatives)","00630(Glyoxylate and dicarboxylate metabolism)","K01816","EC:5.3.1.22","hydroxypyruvate isomerase (putative) [Source:HGNC Symbol;Acc:HGNC:26948]",{"v":1.028534,"d":"1.03"},{"v":0.502469,"d":"0.50"},{"v":0.750038,"d":"0.75"},{"v":0.758171,"d":"0.76"},{"v":0.396271,"d":"0.40"},{"v":0.537341,"d":"0.54"},{"v":1.34830589975192,"d":"1.35"},{"v":0.431147848143366,"d":"0.43"},1,1,"up","no"]
[167036,0,"chr6","-",5236284,5260721,"ENST00000455814",3,450,"ENSG00000214113","LYRM4","GO:0005634(nucleus);GO:0005739(mitochondrion);GO:0005759(mitochondrial matrix);GO:0016604(nuclear body);GO:0044281(small molecule metabolic process)","NA","K22069","NA","LYR motif containing 4 [Source:HGNC Symbol;Acc:HGNC:21365]",{"v":0.042024,"d":"0.04"},{"v":0.137963,"d":"0.14"},0,{"v":0.08738,"d":"0.09"},0,{"v":0.049269,"d":"0.05"},{"v":1.31714831429429,"d":"1.32"},{"v":0.397417805920542,"d":"0.40"},1,1,"up","no"]
[125953,0,"chr20","+",32359237,32429357,"ENST00000643168",7,840,"ENSG00000171456","ASXL1","GO:0000790(nuclear chromatin);GO:0000902(cell morphogenesis);GO:0003007(heart morphogenesis);GO:0003677(DNA binding);GO:0003682(chromatin binding);GO:0003713(transcription coactivator activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0006325(chromatin organization);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0009887(animal organ morphogenesis);GO:0016579(protein deubiquitination);GO:0030097(hemopoiesis);GO:0032526(response to retinoic acid);GO:0035359(negative regulation of peroxisome proliferator activated receptor signaling pathway);GO:0035517(PR-DUB complex);GO:0035522(monoubiquitinated histone H2A deubiquitination);GO:0042974(retinoic acid receptor binding);GO:0042975(peroxisome proliferator activated receptor binding);GO:0045599(negative regulation of fat cell differentiation);GO:0045944(positive regulation of transcription by RNA polymerase II);GO:0046872(metal ion binding);GO:0048386(positive regulation of retinoic acid receptor signaling pathway);GO:0048534(hematopoietic or lymphoid organ development);GO:0048538(thymus development);GO:0048539(bone marrow development);GO:0048872(homeostasis of number of cells);GO:0060348(bone development);GO:0060430(lung saccule development)","NA","K11471","NA","ASXL transcriptional regulator 1 [Source:HGNC Symbol;Acc:HGNC:18318]",{"v":0.002443,"d":"0.00"},{"v":0.054075,"d":"0.05"},0,{"v":0.039458,"d":"0.04"},0,{"v":0.191565,"d":"0.19"},{"v":0.244642308341594,"d":"0.24"},{"v":-2.03125417035013,"d":"-2.03"},1,1,"down","no"]
[69210,0,"chr16","+",410112,411050,"ENST00000469922",2,616,"ENSG00000242612","DECR2","GO:0005102(signaling receptor binding);GO:0005777(peroxisome);GO:0005778(peroxisomal membrane);GO:0005829(cytosol);GO:0006625(protein targeting to peroxisome);GO:0006629(lipid metabolic process);GO:0006631(fatty acid metabolic process);GO:0006636(unsaturated fatty acid biosynthetic process);GO:0008670(2,4-dienoyl-CoA reductase (NADPH) activity);GO:0016491(oxidoreductase activity);GO:0019166(trans-2-enoyl-CoA reductase (NADPH) activity);GO:0033540(fatty acid beta-oxidation using acyl-CoA oxidase);GO:0055114(oxidation-reduction process)","04146(Peroxisome)","K13237","EC:1.3.1.34","2,4-dienoyl-CoA reductase 2 [Source:HGNC Symbol;Acc:HGNC:2754]",{"v":0.149836,"d":"0.15"},{"v":0.099675,"d":"0.10"},{"v":0.051507,"d":"0.05"},{"v":0.158837,"d":"0.16"},{"v":0.058615,"d":"0.06"},{"v":0.081276,"d":"0.08"},{"v":1.00766583648001,"d":"1.01"},{"v":0.0110172896503509,"d":"0.01"},1,1,"up","no"]
[175978,0,"chr7","-",161765,164972,"ENST00000567533",1,3208,"ENSG00000261795","AC093627","NA","NA","NA","NA","novel transcript",{"v":0.052357,"d":"0.05"},{"v":0.066791,"d":"0.07"},{"v":0.060024,"d":"0.06"},{"v":0.065537,"d":"0.07"},{"v":0.039911,"d":"0.04"},{"v":0.128518,"d":"0.13"},{"v":0.765803578297701,"d":"0.77"},{"v":-0.384953693539341,"d":"-0.38"},1,1,"down","no"]
[88085,0,"chr17","+",56978153,56995504,"ENST00000571898",8,722,"ENSG00000121064","SCPEP1","GO:0004180(carboxypeptidase activity);GO:0004185(serine-type carboxypeptidase activity);GO:0005576(extracellular region);GO:0005829(cytosol);GO:0006508(proteolysis);GO:0008233(peptidase activity);GO:0016787(hydrolase activity);GO:0042573(retinoic acid metabolic process);GO:0045776(negative regulation of blood pressure);GO:0051603(proteolysis involved in cellular protein catabolic process);GO:0070062(extracellular exosome);GO:0097755(positive regulation of blood vessel diameter)","NA","K09646","EC:3.4.16.-","serine carboxypeptidase 1 [Source:HGNC Symbol;Acc:HGNC:29507]",{"v":0.104571,"d":"0.10"},0,0,0,0,0,"inf","inf",1,1,"up","no"]
[146285,0,"chr3","+",167915139,167922630,"ENST00000496891",4,554,"ENSG00000244227","LRRC77P","NA","NA","NA","NA","leucine rich repeat containing 77, pseudogene [Source:HGNC Symbol;Acc:HGNC:50536]",0,0,0,0,{"v":0.027229,"d":"0.03"},0,"-inf","-inf",1,1,"down","no"]
[49281,0,"chr12","-",122931326,122959787,"ENST00000426173",9,2134,"ENSG00000150967","ABCB9","GO:0000166(nucleotide binding);GO:0005515(protein binding);GO:0005524(ATP binding);GO:0005764(lysosome);GO:0005765(lysosomal membrane);GO:0015031(protein transport);GO:0015440(peptide-transporting ATPase activity);GO:0015833(peptide transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016887(ATPase activity);GO:0022857(transmembrane transporter activity);GO:0030176(integral component of endoplasmic reticulum membrane);GO:0042626(ATPase activity, coupled to transmembrane movement of substances);GO:0042803(protein homodimerization activity);GO:0043231(intracellular membrane-bounded organelle);GO:0055085(transmembrane transport);GO:1904680(peptide transmembrane transporter activity)","02010(ABC transporters);04142(Lysosome)","K05656","NA","ATP binding cassette subfamily B member 9 [Source:HGNC Symbol;Acc:HGNC:50]",0,0,0,0,0,0,1,0,1,1,"no","no"]
[103114,0,"chr19","+",37256399,37265535,"ENST00000587477",4,623,"ENSG00000226686","LINC01535","NA","NA","NA","NA","long intergenic non-protein coding RNA 1535 [Source:HGNC Symbol;Acc:HGNC:51282]",0,0,0,0,0,{"v":0.178085,"d":"0.18"},"-inf","-inf",1,1,"down","no"]
[49110,0,"chr12","+",122068026,122068558,"ENST00000535337",2,436,"ENSG00000256546","AC156455","NA","NA","NA","NA","novel transcript",{"v":0.158227,"d":"0.16"},0,{"v":0.278291,"d":"0.28"},0,{"v":0.290269,"d":"0.29"},{"v":0.050851,"d":"0.05"},{"v":1.2796611163227,"d":"1.28"},{"v":0.355761801997377,"d":"0.36"},1,1,"up","no"]
[44788,0,"chr12","+",57581678,57582874,"ENST00000552227",2,548,"ENSG00000155980","KIF5A","GO:0000166(nucleotide binding);GO:0003774(motor activity);GO:0003777(microtubule motor activity);GO:0005515(protein binding);GO:0005524(ATP binding);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005856(cytoskeleton);GO:0005871(kinesin complex);GO:0005874(microtubule);GO:0006890(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum);GO:0007018(microtubule-based movement);GO:0007268(chemical synaptic transmission);GO:0007411(axon guidance);GO:0008017(microtubule binding);GO:0008574(ATP-dependent microtubule motor activity, plus-end-directed);GO:0016020(membrane);GO:0016192(vesicle-mediated transport);GO:0016887(ATPase activity);GO:0019886(antigen processing and presentation of exogenous peptide antigen via MHC class II);GO:0019894(kinesin binding);GO:0032839(dendrite cytoplasm);GO:0035253(ciliary rootlet);GO:0043005(neuron projection);GO:0043025(neuronal cell body);GO:0045202(synapse);GO:0048471(perinuclear region of cytoplasm);GO:0048489(synaptic vesicle transport);GO:0098971(anterograde dendritic transport of neurotransmitter receptor complex);GO:0099641(anterograde axonal protein transport);GO:1904115(axon cytoplasm);GO:1990049(retrograde neuronal dense core vesicle transport)","04144(Endocytosis);04728(Dopaminergic synapse)","K10396","NA","kinesin family member 5A [Source:HGNC Symbol;Acc:HGNC:6323]",{"v":0.23031,"d":"0.23"},{"v":0.080079,"d":"0.08"},{"v":0.070035,"d":"0.07"},{"v":0.023804,"d":"0.02"},{"v":0.182738,"d":"0.18"},{"v":0.049066,"d":"0.05"},{"v":1.48831022503208,"d":"1.49"},{"v":0.573675274743752,"d":"0.57"},1,1,"up","no"]
[42421,0,"chr12","-",49005131,49018775,"ENST00000548857",7,553,"ENSG00000181929","PRKAG1","GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0004679(AMP-activated protein kinase activity);GO:0004691(cAMP-dependent protein kinase activity);GO:0005515(protein binding);GO:0005524(ATP binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0006110(regulation of glycolytic process);GO:0006468(protein phosphorylation);GO:0006629(lipid metabolic process);GO:0006631(fatty acid metabolic process);GO:0006633(fatty acid biosynthetic process);GO:0007050(cell cycle arrest);GO:0007165(signal transduction);GO:0007283(spermatogenesis);GO:0008603(cAMP-dependent protein kinase regulator activity);GO:0010628(positive regulation of gene expression);GO:0016020(membrane);GO:0016208(AMP binding);GO:0016236(macroautophagy);GO:0016241(regulation of macroautophagy);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0019901(protein kinase binding);GO:0031588(nucleotide-activated protein kinase complex);GO:0032559(adenyl ribonucleotide binding);GO:0043531(ADP binding);GO:0045860(positive regulation of protein kinase activity);GO:0051170(import into nucleus);GO:0071900(regulation of protein serine/threonine kinase activity);GO:1901796(regulation of signal transduction by p53 class mediator)","04068(FoxO signaling pathway);04152(AMPK signaling pathway);04211(Longevity regulating pathway);04213(Longevity regulating pathway - multiple species);04371(Apelin signaling pathway);04530(Tight junction);04710(Circadian rhythm);04714(Thermogenesis);04910(Insulin signaling pathway);04920(Adipocytokine signaling pathway);04921(Oxytocin signaling pathway);04922(Glucagon signaling pathway);04931(Insulin resistance);04932(Non-alcoholic fatty liver disease (NAFLD));05410(Hypertrophic cardiomyopathy (HCM))","NA","NA","protein kinase AMP-activated non-catalytic subunit gamma 1 [Source:HGNC Symbol;Acc:HGNC:9385]",{"v":0.227408,"d":"0.23"},{"v":0.385871,"d":"0.39"},{"v":0.262752,"d":"0.26"},{"v":0.172378,"d":"0.17"},{"v":0.30814,"d":"0.31"},{"v":0.409469,"d":"0.41"},{"v":0.984318872073412,"d":"0.98"},{"v":-0.0228023396518251,"d":"-0.02"},1,1,"down","no"]
[189391,0,"chr8","+",56211810,56217689,"ENST00000521524",5,703,"ENSG00000170791","CHCHD7","GO:0003674(molecular_function);GO:0005575(cellular_component);GO:0005739(mitochondrion);GO:0005758(mitochondrial intermembrane space);GO:0008150(biological_process)","NA","NA","NA","coiled-coil-helix-coiled-coil-helix domain containing 7 [Source:HGNC Symbol;Acc:HGNC:28314]",{"v":0.250842,"d":"0.25"},{"v":0.298968,"d":"0.30"},0,0,0,0,"inf","inf",1,1,"up","no"]
[148601,0,"chr3","+",196900039,196905224,"ENST00000489744",4,430,"ENSG00000119231","SENP5","GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005730(nucleolus);GO:0006508(proteolysis);GO:0007049(cell cycle);GO:0008233(peptidase activity);GO:0008234(cysteine-type peptidase activity);GO:0016787(hydrolase activity);GO:0016925(protein sumoylation);GO:0016926(protein desumoylation);GO:0019783(ubiquitin-like protein-specific protease activity);GO:0051301(cell division)","NA","K08594","EC:3.4.22.68","SUMO specific peptidase 5 [Source:HGNC Symbol;Acc:HGNC:28407]",0,0,0,{"v":0.007629,"d":"0.01"},0,0,"-inf","-inf",1,1,"down","no"]
[161118,0,"chr5","+",95646879,95657133,"ENST00000458310",6,2788,"ENSG00000175449","RFESD","GO:0005515(protein binding);GO:0016491(oxidoreductase activity);GO:0046872(metal ion binding);GO:0051536(iron-sulfur cluster binding);GO:0051537(2 iron, 2 sulfur cluster binding);GO:0055114(oxidation-reduction process)","NA","NA","NA","Rieske Fe-S domain containing [Source:HGNC Symbol;Acc:HGNC:29587]",{"v":0.142759,"d":"0.14"},{"v":0.015785,"d":"0.02"},0,{"v":0.007541,"d":"0.01"},{"v":0.018607,"d":"0.02"},{"v":0.040647,"d":"0.04"},{"v":2.37359083763755,"d":"2.37"},{"v":1.24707126295526,"d":"1.25"},1,1,"up","no"]
[71976,0,"chr16","+",16335930,16349285,"ENST00000541593",8,699,"ENSG00000183889","AC138969","GO:0005654(nucleoplasm)","NA","NA","NA","novel member of the nuclear pore complex interacting protein NPIP gene family",0,0,0,{"v":0.210368,"d":"0.21"},{"v":0.227359,"d":"0.23"},0,"-inf","-inf",1,1,"down","no"]
[111137,0,"chr2","-",31334321,31414742,"ENST00000379416",36,5715,"ENSG00000158125","XDH","GO:0001933(negative regulation of protein phosphorylation);GO:0001937(negative regulation of endothelial cell proliferation);GO:0004854(xanthine dehydrogenase activity);GO:0004855(xanthine oxidase activity);GO:0005506(iron ion binding);GO:0005576(extracellular region);GO:0005615(extracellular space);GO:0005737(cytoplasm);GO:0005777(peroxisome);GO:0005829(cytosol);GO:0006195(purine nucleotide catabolic process);GO:0006919(activation of cysteine-type endopeptidase activity involved in apoptotic process);GO:0007595(lactation);GO:0009055(electron transfer activity);GO:0009115(xanthine catabolic process);GO:0010629(negative regulation of gene expression);GO:0016491(oxidoreductase activity);GO:0016529(sarcoplasmic reticulum);GO:0022900(electron transport chain);GO:0030856(regulation of epithelial cell differentiation);GO:0042803(protein homodimerization activity);GO:0043546(molybdopterin cofactor binding);GO:0045602(negative regulation of endothelial cell differentiation);GO:0046872(metal ion binding);GO:0050660(flavin adenine dinucleotide binding);GO:0051536(iron-sulfur cluster binding);GO:0051537(2 iron, 2 sulfur cluster binding);GO:0051898(negative regulation of protein kinase B signaling);GO:0055114(oxidation-reduction process);GO:0071949(FAD binding);GO:1900745(positive regulation of p38MAPK cascade);GO:1900747(negative regulation of vascular endothelial growth factor signaling pathway);GO:2000379(positive regulation of reactive oxygen species metabolic process);GO:2001213(negative regulation of vasculogenesis)","00230(Purine metabolism);00232(Caffeine metabolism);00983(Drug metabolism - other enzymes);04146(Peroxisome)","K00106","1.17.3.2;EC:1.17.1.4","xanthine dehydrogenase [Source:HGNC Symbol;Acc:HGNC:12805]",{"v":0.007347,"d":"0.01"},{"v":0.0074,"d":"0.01"},0,{"v":0.02943,"d":"0.03"},{"v":0.027168,"d":"0.03"},0,{"v":0.260556910138167,"d":"0.26"},{"v":-1.9403295784028,"d":"-1.94"},1,1,"down","no"]
[204622,0,"chrX","+",80709928,80710705,"ENST00000415494",1,778,"ENSG00000225715","AL512504","NA","NA","NA","NA","proteasome (prosome, macropain) subunit, alpha type, 1 (PSMA1) pseudogene",0,0,0,0,0,0,1,0,1,1,"no","no"]
[198259,0,"chr9","+",109780403,109943623,"ENST00000483909",6,1418,"ENSG00000243444","PALM2","GO:0005886(plasma membrane);GO:0008360(regulation of cell shape);GO:0016020(membrane)","NA","K16519","NA","paralemmin 2 [Source:HGNC Symbol;Acc:HGNC:15845]",{"v":0.096131,"d":"0.10"},{"v":0.285007,"d":"0.29"},0,0,0,{"v":0.133798,"d":"0.13"},{"v":2.84860760250527,"d":"2.85"},{"v":1.51025690319602,"d":"1.51"},1,1,"up","no"]
[56942,0,"chr14","+",56636516,56650606,"ENST00000555046",2,618,"ENSG00000070269","TMEM260","GO:0016020(membrane);GO:0016021(integral component of membrane)","NA","NA","NA","transmembrane protein 260 [Source:HGNC Symbol;Acc:HGNC:20185]",{"v":0.259831,"d":"0.26"},{"v":0.382265,"d":"0.38"},{"v":0.355339,"d":"0.36"},{"v":0.264488,"d":"0.26"},{"v":0.151798,"d":"0.15"},{"v":0.341288,"d":"0.34"},{"v":1.31661725455203,"d":"1.32"},{"v":0.39683600982144,"d":"0.40"},1,1,"up","no"]
[92582,0,"chr18","+",3262417,3278284,"ENST00000581193",4,1249,"ENSG00000118680","MYL12B","GO:0005509(calcium ion binding);GO:0005515(protein binding);GO:0005829(cytosol);GO:0006936(muscle contraction);GO:0016459(myosin complex);GO:0046872(metal ion binding);GO:0070062(extracellular exosome);GO:0099738(cell cortex region)","04360(Axon guidance);04510(Focal adhesion);04530(Tight junction);04611(Platelet activation);04670(Leukocyte transendothelial migration);04810(Regulation of actin cytoskeleton)","K12757","NA","myosin light chain 12B [Source:HGNC Symbol;Acc:HGNC:29827]",{"v":0.01681,"d":"0.02"},{"v":0.293596,"d":"0.29"},{"v":0.079015,"d":"0.08"},{"v":0.033546,"d":"0.03"},{"v":0.26285,"d":"0.26"},0,{"v":1.31385376320868,"d":"1.31"},{"v":0.393804707293156,"d":"0.39"},1,1,"up","no"]
[146825,0,"chr3","+",179804063,179804366,"ENST00000602704",1,304,"ENSG00000270178","AC007687","NA","NA","NA","NA","novel transcript",0,{"v":0.040554,"d":"0.04"},{"v":0.063597,"d":"0.06"},{"v":0.117226,"d":"0.12"},{"v":0.240842,"d":"0.24"},{"v":0.108103,"d":"0.11"},{"v":0.22341801613571,"d":"0.22"},{"v":-2.16218256733988,"d":"-2.16"},1,1,"down","no"]
[144630,0,"chr3","-",136422957,136473603,"ENST00000492318",6,570,"ENSG00000118007","STAG1","GO:0000775(chromosome, centromeric region);GO:0000785(chromatin);GO:0001228(DNA-binding transcription activator activity, RNA polymerase II-specific);GO:0003682(chromatin binding);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005694(chromosome);GO:0005829(cytosol);GO:0007049(cell cycle);GO:0007059(chromosome segregation);GO:0007062(sister chromatid cohesion);GO:0008278(cohesin complex);GO:0016363(nuclear matrix);GO:0016604(nuclear body);GO:0045944(positive regulation of transcription by RNA polymerase II);GO:0051301(cell division);GO:0097431(mitotic spindle pole);GO:1901673(regulation of mitotic spindle assembly)","04110(Cell cycle)","K06671","NA","stromal antigen 1 [Source:HGNC Symbol;Acc:HGNC:11354]",{"v":0.393746,"d":"0.39"},0,0,{"v":0.164894,"d":"0.16"},{"v":0.480137,"d":"0.48"},{"v":0.15603,"d":"0.16"},{"v":0.491530607531761,"d":"0.49"},{"v":-1.02464683913652,"d":"-1.02"},1,1,"down","no"]
[166636,0,"chr5","+",181192070,181194428,"ENST00000508877",3,392,"ENSG00000250222","AC008443","NA","NA","NA","NA","novel transcript",{"v":0.323762,"d":"0.32"},{"v":0.190917,"d":"0.19"},{"v":0.060419,"d":"0.06"},{"v":0.152521,"d":"0.15"},{"v":0.301848,"d":"0.30"},{"v":0.251285,"d":"0.25"},{"v":0.814985814577682,"d":"0.81"},{"v":-0.295153146484182,"d":"-0.30"},1,1,"down","no"]
[182108,0,"chr7","+",100604988,100605765,"ENST00000490909",2,318,"ENSG00000106333","PCOLCE","GO:0005201(extracellular matrix structural constituent);GO:0005515(protein binding);GO:0005518(collagen binding);GO:0005576(extracellular region);GO:0005615(extracellular space);GO:0006508(proteolysis);GO:0007275(multicellular organism development);GO:0008201(heparin binding);GO:0010952(positive regulation of peptidase activity);GO:0016504(peptidase activator activity);GO:0062023(collagen-containing extracellular matrix);GO:0070062(extracellular exosome);GO:1990830(cellular response to leukemia inhibitory factor)","NA","NA","NA","procollagen C-endopeptidase enhancer [Source:HGNC Symbol;Acc:HGNC:8738]",{"v":0.379528,"d":"0.38"},{"v":0.412869,"d":"0.41"},{"v":0.571543,"d":"0.57"},{"v":0.370531,"d":"0.37"},{"v":0.348244,"d":"0.35"},{"v":0.248562,"d":"0.25"},{"v":1.40999465543032,"d":"1.41"},{"v":0.495689694114292,"d":"0.50"},1,1,"up","no"]
[157587,0,"chr5","-",10307197,10307548,"ENST00000506224",2,218,"ENSG00000164237","CMBL","GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0006805(xenobiotic metabolic process);GO:0016787(hydrolase activity);GO:0070062(extracellular exosome)","NA","NA","NA","carboxymethylenebutenolidase homolog [Source:HGNC Symbol;Acc:HGNC:25090]",0,0,0,0,0,0,1,0,1,1,"no","no"]
[56584,0,"chr14","+",51554660,51579297,"ENST00000555952",3,535,"ENSG00000139926","FRMD6","GO:0003383(apical constriction);GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0005856(cytoskeleton);GO:0005886(plasma membrane);GO:0016020(membrane);GO:0031032(actomyosin structure organization);GO:0032970(regulation of actin filament-based process);GO:0034613(cellular protein localization);GO:0043296(apical junction complex)","04390(Hippo signaling pathway);04392(Hippo signaling pathway - multiple species)","K16822","NA","FERM domain containing 6 [Source:HGNC Symbol;Acc:HGNC:19839]",{"v":0.035904,"d":"0.04"},0,0,0,0,0,"inf","inf",1,1,"up","no"]
[193174,0,"chr8","-",140890584,141001266,"ENST00000524040",4,475,"ENSG00000169398","PTK2","GO:0000165(MAPK cascade);GO:0000166(nucleotide binding);GO:0000226(microtubule cytoskeleton organization);GO:0001525(angiogenesis);GO:0001568(blood vessel development);GO:0001570(vasculogenesis);GO:0001725(stress fiber);GO:0001764(neuron migration);GO:0001890(placenta development);GO:0001932(regulation of protein phosphorylation);GO:0001934(positive regulation of protein phosphorylation);GO:0003007(heart morphogenesis);GO:0003779(actin binding);GO:0004672(protein kinase activity);GO:0004713(protein tyrosine kinase activity);GO:0004715(non-membrane spanning protein tyrosine kinase activity);GO:0005515(protein binding);GO:0005524(ATP binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005815(microtubule organizing center);GO:0005829(cytosol);GO:0005856(cytoskeleton);GO:0005886(plasma membrane);GO:0005925(focal adhesion);GO:0005938(cell cortex);GO:0006468(protein phosphorylation);GO:0007097(nuclear migration);GO:0007172(signal complex assembly);GO:0007173(epidermal growth factor receptor signaling pathway);GO:0007179(transforming growth factor beta receptor signaling pathway);GO:0007229(integrin-mediated signaling pathway);GO:0007275(multicellular organism development);GO:0007411(axon guidance);GO:0008284(positive regulation of cell population proliferation);GO:0008360(regulation of cell shape);GO:0008432(JUN kinase binding);GO:0010507(negative regulation of autophagy);GO:0010594(regulation of endothelial cell migration);GO:0010613(positive regulation of cardiac muscle hypertrophy);GO:0010632(regulation of epithelial cell migration);GO:0014068(positive regulation of phosphatidylinositol 3-kinase signaling);GO:0016020(membrane);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0016324(apical plasma membrane);GO:0016740(transferase activity);GO:0018108(peptidyl-tyrosine phosphorylation);GO:0019901(protein kinase binding);GO:0019903(protein phosphatase binding);GO:0021955(central nervous system neuron axonogenesis);GO:0022408(negative regulation of cell-cell adhesion);GO:0030010(establishment of cell polarity);GO:0030027(lamellipodium);GO:0030054(cell junction);GO:0030154(cell differentiation);GO:0030155(regulation of cell adhesion);GO:0030198(extracellular matrix organization);GO:0030335(positive regulation of cell migration);GO:0033628(regulation of cell adhesion mediated by integrin);GO:0038007(netrin-activated signaling pathway);GO:0038083(peptidyl-tyrosine autophosphorylation);GO:0038096(Fc-gamma receptor signaling pathway involved in phagocytosis);GO:0042127(regulation of cell population proliferation);GO:0042169(SH2 domain binding);GO:0043066(negative regulation of apoptotic process);GO:0043087(regulation of GTPase activity);GO:0043197(dendritic spine);GO:0043542(endothelial cell migration);GO:0043552(positive regulation of phosphatidylinositol 3-kinase activity);GO:0045667(regulation of osteoblast differentiation);GO:0045860(positive regulation of protein kinase activity);GO:0046621(negative regulation of organ growth);GO:0046777(protein autophosphorylation);GO:0048010(vascular endothelial growth factor receptor signaling pathway);GO:0048013(ephrin receptor signaling pathway);GO:0048870(cell motility);GO:0050771(negative regulation of axonogenesis);GO:0051493(regulation of cytoskeleton organization);GO:0051893(regulation of focal adhesion assembly);GO:0051897(positive regulation of protein kinase B signaling);GO:0051964(negative regulation of synapse assembly);GO:0060396(growth hormone receptor signaling pathway);GO:0071560(cellular response to transforming growth factor beta stimulus);GO:1900024(regulation of substrate adhesion-dependent cell spreading);GO:2000060(positive regulation of ubiquitin-dependent protein catabolic process);GO:2000811(negative regulation of anoikis)","01522(Endocrine resistance);04012(ErbB signaling pathway);04062(Chemokine signaling pathway);04151(PI3K-Akt signaling pathway);04360(Axon guidance);04370(VEGF signaling pathway);04510(Focal adhesion);04670(Leukocyte transendothelial migration);04810(Regulation of actin cytoskeleton);05100(Bacterial invasion of epithelial cells);05146(Amoebiasis);05163(Human cytomegalovirus infection);05165(Human papillomavirus infection);05170(Human immunodeficiency virus 1 infection);05200(Pathways in cancer);05202(Transcriptional misregulation in cancer);05205(Proteoglycans in cancer);05222(Small cell lung cancer);05418(Fluid shear stress and atherosclerosis)","NA","NA","protein tyrosine kinase 2 [Source:HGNC Symbol;Acc:HGNC:9611]",{"v":0.224781,"d":"0.22"},{"v":0.136603,"d":"0.14"},0,0,{"v":0.313216,"d":"0.31"},{"v":0.38471,"d":"0.38"},{"v":0.517797015729461,"d":"0.52"},{"v":-0.949541444451798,"d":"-0.95"},1,1,"down","no"]
[177741,0,"chr7","+",30028361,30118345,"ENST00000622102",14,2140,"ENSG00000106086","PLEKHA8","GO:0000139(Golgi membrane);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0005794(Golgi apparatus);GO:0005802(trans-Golgi network);GO:0005829(cytosol);GO:0006661(phosphatidylinositol biosynthetic process);GO:0006869(lipid transport);GO:0008289(lipid binding);GO:0015031(protein transport);GO:0016020(membrane);GO:0017089(glycolipid transporter activity);GO:0035621(ER to Golgi ceramide transport);GO:0035627(ceramide transport);GO:0046836(glycolipid transport);GO:0051861(glycolipid binding);GO:0070273(phosphatidylinositol-4-phosphate binding);GO:0097001(ceramide binding);GO:0120009(intermembrane lipid transfer);GO:0120013(intermembrane lipid transfer activity);GO:1902387(ceramide 1-phosphate binding);GO:1902388(ceramide 1-phosphate transporter activity);GO:1902389(ceramide 1-phosphate transport)","NA","K08051","NA","pleckstrin homology domain containing A8 [Source:HGNC Symbol;Acc:HGNC:30037]",{"v":0.031154,"d":"0.03"},{"v":0.353733,"d":"0.35"},{"v":0.079519,"d":"0.08"},{"v":0.53945,"d":"0.54"},{"v":0.012215,"d":"0.01"},{"v":0.032328,"d":"0.03"},{"v":0.795225285234583,"d":"0.80"},{"v":-0.330564464870227,"d":"-0.33"},1,1,"down","no"]
[7292,0,"chr1","+",68479129,68483539,"ENST00000425820",2,960,"ENSG00000233589","AL138789","NA","NA","NA","NA","novel transcript",0,0,0,0,0,0,1,0,1,1,"no","no"]
[74842,0,"chr16","+",51152121,51273213,"ENST00000644069",3,1316,"ENSG00000285367","AC087564","NA","NA","NA","NA","novel transcript",{"v":0.032981,"d":"0.03"},0,{"v":0.066821,"d":"0.07"},{"v":0.031838,"d":"0.03"},0,0,{"v":3.13468182674791,"d":"3.13"},{"v":1.64831901550962,"d":"1.65"},1,1,"up","no"]
[174099,0,"chr6","+",133952286,133980260,"ENST00000457715",3,865,"ENSG00000028839","TBPL1","GO:0000126(transcription factor TFIIIB complex);GO:0000978(RNA polymerase II proximal promoter sequence-specific DNA binding);GO:0000979(RNA polymerase II core promoter sequence-specific DNA binding);GO:0000981(DNA-binding transcription factor activity, RNA polymerase II-specific);GO:0001016(RNA polymerase III regulatory region DNA binding);GO:0001228(DNA-binding transcription activator activity, RNA polymerase II-specific);GO:0001675(acrosome assembly);GO:0003677(DNA binding);GO:0003700(DNA-binding transcription factor activity);GO:0003713(transcription coactivator activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005667(transcription factor complex);GO:0005669(transcription factor TFIID complex);GO:0005672(transcription factor TFIIA complex);GO:0005737(cytoplasm);GO:0006235(dTTP biosynthetic process);GO:0006352(DNA-templated transcription, initiation);GO:0006366(transcription by RNA polymerase II);GO:0007283(spermatogenesis);GO:0007289(spermatid nucleus differentiation);GO:0008134(transcription factor binding);GO:0045944(positive regulation of transcription by RNA polymerase II);GO:0070898(RNA polymerase III preinitiation complex assembly)","03022(Basal transcription factors);05016(Huntington disease);05165(Human papillomavirus infection);05166(Human T-cell leukemia virus 1 infection);05203(Viral carcinogenesis)","K03120","NA","TATA-box binding protein like 1 [Source:HGNC Symbol;Acc:HGNC:11589]",{"v":0.006375,"d":"0.01"},{"v":0.00281,"d":"0.00"},{"v":0.616392,"d":"0.62"},{"v":0.307829,"d":"0.31"},{"v":0.115186,"d":"0.12"},{"v":0.154094,"d":"0.15"},{"v":1.08398413471285,"d":"1.08"},{"v":0.116343641434783,"d":"0.12"},1,1,"up","no"]
[54885,0,"chr14","+",23556136,23557125,"ENST00000557630",2,581,"ENSG00000259431","THTPA","GO:0000287(magnesium ion binding);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0006091(generation of precursor metabolites and energy);GO:0006772(thiamine metabolic process);GO:0016311(dephosphorylation);GO:0016787(hydrolase activity);GO:0042357(thiamine diphosphate metabolic process);GO:0042723(thiamine-containing compound metabolic process);GO:0046872(metal ion binding);GO:0050333(thiamin-triphosphatase activity)","00730(Thiamine metabolism)","K05307","EC:3.6.1.28","thiamine triphosphatase [Source:HGNC Symbol;Acc:HGNC:18987]",{"v":0.036589,"d":"0.04"},0,{"v":0.080898,"d":"0.08"},{"v":0.127579,"d":"0.13"},{"v":0.299994,"d":"0.30"},0,{"v":0.274776470918416,"d":"0.27"},{"v":-1.86366962327371,"d":"-1.86"},1,1,"down","no"]
[168722,0,"chr6","-",30730919,30742307,"ENST00000413165",6,856,"ENSG00000137312","FLOT1","GO:0001765(membrane raft assembly);GO:0001819(positive regulation of cytokine production);GO:0001931(uropod);GO:0001934(positive regulation of protein phosphorylation);GO:0002020(protease binding);GO:0002090(regulation of receptor internalization);GO:0005515(protein binding);GO:0005765(lysosomal membrane);GO:0005768(endosome);GO:0005769(early endosome);GO:0005815(microtubule organizing center);GO:0005886(plasma membrane);GO:0005901(caveola);GO:0005911(cell-cell junction);GO:0005913(cell-cell adherens junction);GO:0005925(focal adhesion);GO:0007409(axonogenesis);GO:0008180(COP9 signalosome);GO:0009897(external side of plasma membrane);GO:0016020(membrane);GO:0016323(basolateral plasma membrane);GO:0016600(flotillin complex);GO:0022617(extracellular matrix disassembly);GO:0030027(lamellipodium);GO:0030864(cortical actin cytoskeleton);GO:0031410(cytoplasmic vesicle);GO:0032092(positive regulation of protein binding);GO:0032226(positive regulation of synaptic transmission, dopaminergic);GO:0032728(positive regulation of interferon-beta production);GO:0033227(dsRNA transport);GO:0034116(positive regulation of heterotypic cell-cell adhesion);GO:0034141(positive regulation of toll-like receptor 3 signaling pathway);GO:0034451(centriolar satellite);GO:0034976(response to endoplasmic reticulum stress);GO:0035023(regulation of Rho protein signal transduction);GO:0035255(ionotropic glutamate receptor binding);GO:0042383(sarcolemma);GO:0042470(melanosome);GO:0044291(cell-cell contact zone);GO:0044853(plasma membrane raft);GO:0044854(plasma membrane raft assembly);GO:0045121(membrane raft);GO:0045202(synapse);GO:0045807(positive regulation of endocytosis);GO:0046982(protein heterodimerization activity);GO:0048643(positive regulation of skeletal muscle tissue development);GO:0048786(presynaptic active zone);GO:0050821(protein stabilization);GO:0051092(positive regulation of NF-kappaB transcription factor activity);GO:0051260(protein homooligomerization);GO:0051580(regulation of neurotransmitter uptake);GO:0060355(positive regulation of cell adhesion molecule production);GO:0070062(extracellular exosome);GO:0070528(protein kinase C signaling);GO:0071360(cellular response to exogenous dsRNA);GO:0072659(protein localization to plasma membrane);GO:0098691(dopaminergic synapse);GO:0098793(presynapse);GO:0098978(glutamatergic synapse);GO:0098982(GABA-ergic synapse);GO:1901741(positive regulation of myoblast fusion);GO:1901890(positive regulation of cell junction assembly);GO:1903044(protein localization to membrane raft);GO:2000049(positive regulation of cell-cell adhesion mediated by cadherin)","04910(Insulin signaling pathway)","K07192","NA","flotillin 1 [Source:HGNC Symbol;Acc:HGNC:3757]",{"v":1.048077,"d":"1.05"},{"v":0.561635,"d":"0.56"},{"v":0.285198,"d":"0.29"},{"v":0.437135,"d":"0.44"},{"v":0.423977,"d":"0.42"},{"v":0.677893,"d":"0.68"},{"v":1.23125655862067,"d":"1.23"},{"v":0.300131409494342,"d":"0.30"},1,1,"up","no"]
[147249,0,"chr3","+",184135389,184145292,"ENST00000492226",12,3790,"ENSG00000145191","EIF2B5","GO:0001541(ovarian follicle development);GO:0003743(translation initiation factor activity);GO:0005085(guanyl-nucleotide exchange factor activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005851(eukaryotic translation initiation factor 2B complex);GO:0006412(translation);GO:0006413(translational initiation);GO:0007568(aging);GO:0009408(response to heat);GO:0009749(response to glucose);GO:0010226(response to lithium ion);GO:0014002(astrocyte development);GO:0014003(oligodendrocyte development);GO:0021766(hippocampus development);GO:0031369(translation initiation factor binding);GO:0034976(response to endoplasmic reticulum stress);GO:0042552(myelination);GO:0043065(positive regulation of apoptotic process);GO:0043434(response to peptide hormone);GO:0045727(positive regulation of translation);GO:0045948(positive regulation of translational initiation);GO:0048708(astrocyte differentiation);GO:0050852(T cell receptor signaling pathway)","03013(RNA transport);05168(Herpes simplex virus 1 infection)","K03240","NA","eukaryotic translation initiation factor 2B subunit epsilon [Source:HGNC Symbol;Acc:HGNC:3261]",0,{"v":0.472407,"d":"0.47"},{"v":0.234378,"d":"0.23"},{"v":0.623689,"d":"0.62"},{"v":0.053263,"d":"0.05"},0,{"v":1.04406959429915,"d":"1.04"},{"v":0.0622178804939145,"d":"0.06"},1,1,"up","no"]
[76410,0,"chr16","+",67538464,67541578,"ENST00000566815",10,929,"ENSG00000039523","RIPOR1","GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0005794(Golgi apparatus);GO:0007266(Rho protein signal transduction);GO:0009267(cellular response to starvation);GO:0009611(response to wounding);GO:0012506(vesicle membrane);GO:0016020(membrane);GO:0030335(positive regulation of cell migration);GO:0034067(protein localization to Golgi apparatus);GO:0051683(establishment of Golgi localization);GO:0070062(extracellular exosome);GO:0071889(14-3-3 protein binding);GO:0090316(positive regulation of intracellular protein transport)","NA","NA","NA","RHO family interacting cell polarization regulator 1 [Source:HGNC Symbol;Acc:HGNC:25836]",{"v":0.257221,"d":"0.26"},{"v":0.156305,"d":"0.16"},{"v":0.327985,"d":"0.33"},{"v":0.258186,"d":"0.26"},{"v":0.253682,"d":"0.25"},{"v":0.093992,"d":"0.09"},{"v":1.22389826032417,"d":"1.22"},{"v":0.291483635296643,"d":"0.29"},1,1,"up","no"]
[5404,0,"chr1","+",44051193,44076822,"ENST00000609027",5,940,"ENSG00000230615","AL139220","NA","NA","NA","NA","novel transcript",0,0,0,{"v":0.044732,"d":"0.04"},0,0,"-inf","-inf",1,1,"down","no"]
[191773,0,"chr8","-",104379431,104467055,"ENST00000351513",10,2122,"ENSG00000147647","DPYS","GO:0002058(uracil binding);GO:0002059(thymine binding);GO:0004157(dihydropyrimidinase activity);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0006208(pyrimidine nucleobase catabolic process);GO:0006210(thymine catabolic process);GO:0006212(uracil catabolic process);GO:0008270(zinc ion binding);GO:0016597(amino acid binding);GO:0016787(hydrolase activity);GO:0016810(hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds);GO:0019482(beta-alanine metabolic process);GO:0019860(uracil metabolic process);GO:0046135(pyrimidine nucleoside catabolic process);GO:0046872(metal ion binding);GO:0051219(phosphoprotein binding);GO:0051260(protein homooligomerization);GO:0051289(protein homotetramerization);GO:0070062(extracellular exosome)","00240(Pyrimidine metabolism);00410(beta-Alanine metabolism);00770(Pantothenate and CoA biosynthesis);00983(Drug metabolism - other enzymes)","K01464","EC:3.5.2.2","dihydropyrimidinase [Source:HGNC Symbol;Acc:HGNC:3013]",{"v":0.019788,"d":"0.02"},{"v":0.043782,"d":"0.04"},0,0,0,0,"inf","inf",1,1,"up","no"]
[104256,0,"chr19","+",41376969,41382904,"ENST00000537354",3,450,"ENSG00000142046","TMEM91","GO:0002244(hematopoietic progenitor cell differentiation);GO:0003674(molecular_function);GO:0005575(cellular_component);GO:0008150(biological_process);GO:0016020(membrane);GO:0016021(integral component of membrane)","NA","NA","NA","transmembrane protein 91 [Source:HGNC Symbol;Acc:HGNC:32393]",0,0,{"v":0.035696,"d":"0.04"},0,{"v":0.031886,"d":"0.03"},{"v":0.027255,"d":"0.03"},{"v":0.603574508378282,"d":"0.60"},{"v":-0.728396219130197,"d":"-0.73"},1,1,"down","no"]
[98272,0,"chr19","-",8334113,8334782,"ENST00000593331",2,590,"ENSG00000186994","KANK3","GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0030837(negative regulation of actin filament polymerization)","NA","K22808","NA","KN motif and ankyrin repeat domains 3 [Source:HGNC Symbol;Acc:HGNC:24796]",0,0,0,0,0,0,1,0,1,1,"no","no"]
[174887,0,"chr6","+",149749728,149810628,"ENST00000649032",8,861,"ENSG00000120265","PCMT1","GO:0004719(protein-L-isoaspartate (D-aspartate) O-methyltransferase activity);GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0006464(cellular protein modification process);GO:0006479(protein methylation);GO:0008168(methyltransferase activity);GO:0016740(transferase activity);GO:0030091(protein repair);GO:0032259(methylation);GO:0045296(cadherin binding);GO:0070062(extracellular exosome);GO:1903561(extracellular vesicle)","NA","NA","NA","protein-L-isoaspartate (D-aspartate) O-methyltransferase [Source:HGNC Symbol;Acc:HGNC:8728]",{"v":0.541044,"d":"0.54"},{"v":0.666295,"d":"0.67"},{"v":0.097972,"d":"0.10"},{"v":0.294654,"d":"0.29"},{"v":0.259542,"d":"0.26"},{"v":0.578383,"d":"0.58"},{"v":1.15251209849379,"d":"1.15"},{"v":0.20478189542284,"d":"0.20"},1,1,"up","no"]
[147171,0,"chr3","-",183806457,183809515,"ENST00000425008",2,2442,"ENSG00000233885","YEATS2-AS1","NA","NA","NA","NA","YEATS2 antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:41101]",{"v":0.117589,"d":"0.12"},{"v":0.276859,"d":"0.28"},{"v":0.240589,"d":"0.24"},{"v":0.160336,"d":"0.16"},{"v":0.271503,"d":"0.27"},{"v":0.204021,"d":"0.20"},{"v":0.998705689931746,"d":"1.00"},{"v":-0.00186850418975333,"d":"-0.00"},1,1,"down","no"]
[200135,0,"chr9","-",132891353,132944619,"ENST00000642627",23,8579,"ENSG00000165699","TSC1","GO:0001822(kidney development);GO:0001843(neural tube closure);GO:0001952(regulation of cell-matrix adhesion);GO:0002250(adaptive immune response);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005811(lipid droplet);GO:0005829(cytosol);GO:0005856(cytoskeleton);GO:0005884(actin filament);GO:0005886(plasma membrane);GO:0005938(cell cortex);GO:0006407(rRNA export from nucleus);GO:0006417(regulation of translation);GO:0006813(potassium ion transport);GO:0007160(cell-matrix adhesion);GO:0007399(nervous system development);GO:0008285(negative regulation of cell population proliferation);GO:0008344(adult locomotory behavior);GO:0010977(negative regulation of neuron projection development);GO:0014069(postsynaptic density);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016239(positive regulation of macroautophagy);GO:0016242(negative regulation of macroautophagy);GO:0017148(negative regulation of translation);GO:0021766(hippocampus development);GO:0021987(cerebral cortex development);GO:0030027(lamellipodium);GO:0030030(cell projection organization);GO:0030426(growth cone);GO:0030544(Hsp70 protein binding);GO:0032007(negative regulation of TOR signaling);GO:0032780(negative regulation of ATPase activity);GO:0032794(GTPase activating protein binding);GO:0032868(response to insulin);GO:0032991(protein-containing complex);GO:0033596(TSC1-TSC2 complex);GO:0034260(negative regulation of GTPase activity);GO:0042030(ATPase inhibitor activity);GO:0042552(myelination);GO:0042995(cell projection);GO:0043231(intracellular membrane-bounded organelle);GO:0043379(memory T cell differentiation);GO:0043666(regulation of phosphoprotein phosphatase activity);GO:0045792(negative regulation of cell size);GO:0045859(regulation of protein kinase activity);GO:0046323(glucose import);GO:0046627(negative regulation of insulin receptor signaling pathway);GO:0047485(protein N-terminus binding);GO:0048471(perinuclear region of cytoplasm);GO:0050808(synapse organization);GO:0050821(protein stabilization);GO:0051087(chaperone binding);GO:0051291(protein heterooligomerization);GO:0051492(regulation of stress fiber assembly);GO:0051496(positive regulation of stress fiber assembly);GO:0051726(regulation of cell cycle);GO:0051879(Hsp90 protein binding);GO:0051893(regulation of focal adhesion assembly);GO:0051894(positive regulation of focal adhesion assembly);GO:0055007(cardiac muscle cell differentiation);GO:0090630(activation of GTPase activity);GO:0090650(cellular response to oxygen-glucose deprivation);GO:0101031(chaperone complex);GO:1901214(regulation of neuron death);GO:1903204(negative regulation of oxidative stress-induced neuron death)","04072(Phospholipase D signaling pathway);04140(Autophagy - animal);04150(mTOR signaling pathway);04151(PI3K-Akt signaling pathway);04152(AMPK signaling pathway);04211(Longevity regulating pathway);04218(Cellular senescence);04714(Thermogenesis);04910(Insulin signaling pathway);05163(Human cytomegalovirus infection);05165(Human papillomavirus infection);05168(Herpes simplex virus 1 infection);05231(Choline metabolism in cancer)","K07206","NA","TSC complex subunit 1 [Source:HGNC Symbol;Acc:HGNC:12362]",0,0,0,{"v":0.000855,"d":"0.00"},0,0,"-inf","-inf",1,1,"down","no"]
[103611,0,"chr19","-",39025519,39031402,"ENST00000595166",4,462,"ENSG00000161243","FBXO27","GO:0000209(protein polyubiquitination);GO:0005515(protein binding);GO:0005829(cytosol);GO:0019005(SCF ubiquitin ligase complex);GO:0043687(post-translational protein modification)","NA","K10102","NA","F-box protein 27 [Source:HGNC Symbol;Acc:HGNC:18753]",{"v":0.028457,"d":"0.03"},{"v":0.306477,"d":"0.31"},{"v":0.08616,"d":"0.09"},{"v":0.151627,"d":"0.15"},{"v":0.557177,"d":"0.56"},{"v":0.217328,"d":"0.22"},{"v":0.454680326346568,"d":"0.45"},{"v":-1.13707551371296,"d":"-1.14"},1,1,"down","no"]
[8983,0,"chr1","-",108815898,108817454,"ENST00000466413",2,812,"ENSG00000162641","AKNAD1","NA","NA","NA","NA","AKNA domain containing 1 [Source:HGNC Symbol;Acc:HGNC:28398]",0,0,0,{"v":0.051784,"d":"0.05"},0,{"v":0.108829,"d":"0.11"},"-inf","-inf",1,1,"down","no"]
[135137,0,"chr22","+",41873689,41877396,"ENST00000462539",4,796,"ENSG00000198911","SREBF2","GO:0000122(negative regulation of transcription by RNA polymerase II);GO:0000139(Golgi membrane);GO:0000978(RNA polymerase II proximal promoter sequence-specific DNA binding);GO:0000981(DNA-binding transcription factor activity, RNA polymerase II-specific);GO:0001227(DNA-binding transcription repressor activity, RNA polymerase II-specific);GO:0003677(DNA binding);GO:0003700(DNA-binding transcription factor activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0005739(mitochondrion);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005794(Golgi apparatus);GO:0005829(cytosol);GO:0006355(regulation of transcription, DNA-templated);GO:0006629(lipid metabolic process);GO:0008022(protein C-terminus binding);GO:0008202(steroid metabolic process);GO:0008203(cholesterol metabolic process);GO:0009267(cellular response to starvation);GO:0010886(positive regulation of cholesterol storage);GO:0012507(ER to Golgi transport vesicle membrane);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0031410(cytoplasmic vesicle);GO:0032937(SREBP-SCAP-Insig complex);GO:0042632(cholesterol homeostasis);GO:0043231(intracellular membrane-bounded organelle);GO:0044212(transcription regulatory region DNA binding);GO:0045540(regulation of cholesterol biosynthetic process);GO:0045944(positive regulation of transcription by RNA polymerase II);GO:0046983(protein dimerization activity);GO:0070888(E-box binding);GO:0071404(cellular response to low-density lipoprotein particle stimulus);GO:0071499(cellular response to laminar fluid shear stress);GO:0072368(regulation of lipid transport by negative regulation of transcription from RNA polymerase II promoter);GO:0090370(negative regulation of cholesterol efflux);GO:1902895(positive regulation of pri-miRNA transcription by RNA polymerase II);GO:1903146(regulation of autophagy of mitochondrion);GO:1903955(positive regulation of protein targeting to mitochondrion)","NA","K09107","NA","sterol regulatory element binding transcription factor 2 [Source:HGNC Symbol;Acc:HGNC:11290]",{"v":0.002757,"d":"0.00"},{"v":0.246176,"d":"0.25"},{"v":0.239042,"d":"0.24"},{"v":0.283155,"d":"0.28"},{"v":0.001951,"d":"0.00"},{"v":0.251114,"d":"0.25"},{"v":0.910027600611689,"d":"0.91"},{"v":-0.136017792804868,"d":"-0.14"},1,1,"down","no"]
[143108,0,"chr3","-",115810276,115842497,"ENST00000475403",6,477,"ENSG00000185565","LSAMP","GO:0005515(protein binding);GO:0005576(extracellular region);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0007155(cell adhesion);GO:0007399(nervous system development);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0031225(anchored component of membrane)","NA","K06772","NA","limbic system associated membrane protein [Source:HGNC Symbol;Acc:HGNC:6705]",0,0,{"v":0.015036,"d":"0.02"},0,0,0,"inf","inf",1,1,"up","no"]
[13231,0,"chr1","+",161202046,161209516,"ENST00000496553",5,888,"ENSG00000158864","NDUFS2","GO:0003954(NADH dehydrogenase activity);GO:0005515(protein binding);GO:0005654(nucleoplasm);GO:0005739(mitochondrion);GO:0005743(mitochondrial inner membrane);GO:0005747(mitochondrial respiratory chain complex I);GO:0005759(mitochondrial matrix);GO:0006120(mitochondrial electron transport, NADH to ubiquinone);GO:0006979(response to oxidative stress);GO:0008137(NADH dehydrogenase (ubiquinone) activity);GO:0009055(electron transfer activity);GO:0016020(membrane);GO:0016491(oxidoreductase activity);GO:0016651(oxidoreductase activity, acting on NAD(P)H);GO:0031625(ubiquitin protein ligase binding);GO:0032981(mitochondrial respiratory chain complex I assembly);GO:0042775(mitochondrial ATP synthesis coupled electron transport);GO:0046872(metal ion binding);GO:0048038(quinone binding);GO:0051287(NAD binding);GO:0051536(iron-sulfur cluster binding);GO:0051539(4 iron, 4 sulfur cluster binding);GO:0055114(oxidation-reduction process);GO:0070469(respirasome)","00190(Oxidative phosphorylation);04714(Thermogenesis);04723(Retrograde endocannabinoid signaling);04932(Non-alcoholic fatty liver disease (NAFLD));05010(Alzheimer disease);05012(Parkinson disease);05016(Huntington disease)","K03935","1.6.99.3;EC:7.1.1.2","NADH:ubiquinone oxidoreductase core subunit S2 [Source:HGNC Symbol;Acc:HGNC:7708]",{"v":0.13695,"d":"0.14"},{"v":0.109057,"d":"0.11"},{"v":0.18907,"d":"0.19"},{"v":0.02955,"d":"0.03"},{"v":0.103147,"d":"0.10"},{"v":0.078589,"d":"0.08"},{"v":2.05918518027697,"d":"2.06"},{"v":1.04207357579545,"d":"1.04"},1,1,"up","no"]
[177758,0,"chr7","-",30176387,30179014,"ENST00000430537",2,674,"ENSG00000227017","AC007036","NA","NA","NA","NA","novel transcript",0,0,0,0,0,0,1,0,1,1,"no","no"]
[163345,0,"chr5","-",139475575,139482173,"ENST00000652271",6,2295,"ENSG00000184584","TMEM173","GO:0000166(nucleotide binding);GO:0002218(activation of innate immune response);GO:0002230(positive regulation of defense response to virus by host);GO:0002376(immune system process);GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0005739(mitochondrion);GO:0005741(mitochondrial outer membrane);GO:0005777(peroxisome);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005794(Golgi apparatus);GO:0005886(plasma membrane);GO:0006915(apoptotic process);GO:0008134(transcription factor binding);GO:0010468(regulation of gene expression);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016032(viral process);GO:0019901(protein kinase binding);GO:0030659(cytoplasmic vesicle membrane);GO:0030667(secretory granule membrane);GO:0031323(regulation of cellular metabolic process);GO:0031625(ubiquitin protein ligase binding);GO:0032092(positive regulation of protein binding);GO:0032479(regulation of type I interferon production);GO:0032481(positive regulation of type I interferon production);GO:0032608(interferon-beta production);GO:0035438(cyclic-di-GMP binding);GO:0035458(cellular response to interferon-beta);GO:0039528(cytoplasmic pattern recognition receptor signaling pathway in response to virus);GO:0042802(identical protein binding);GO:0042803(protein homodimerization activity);GO:0043312(neutrophil degranulation);GO:0045087(innate immune response);GO:0045944(positive regulation of transcription by RNA polymerase II);GO:0048471(perinuclear region of cytoplasm);GO:0050727(regulation of inflammatory response);GO:0051091(positive regulation of DNA-binding transcription factor activity);GO:0051607(defense response to virus);GO:0061507(cyclic-GMP-AMP binding);GO:0071360(cellular response to exogenous dsRNA);GO:0071407(cellular response to organic cyclic compound)","04621(NOD-like receptor signaling pathway);04622(RIG-I-like receptor signaling pathway);04623(Cytosolic DNA-sensing pathway);05163(Human cytomegalovirus infection);05168(Herpes simplex virus 1 infection);05170(Human immunodeficiency virus 1 infection)","K12654","NA","transmembrane protein 173 [Source:HGNC Symbol;Acc:HGNC:27962]",{"v":0.000414,"d":"0.00"},{"v":0.014574,"d":"0.01"},{"v":0.05961,"d":"0.06"},{"v":0.095992,"d":"0.10"},{"v":0.013928,"d":"0.01"},{"v":0.012499,"d":"0.01"},{"v":0.609366193156291,"d":"0.61"},{"v":-0.714618631486975,"d":"-0.71"},1,1,"down","no"]
[40953,0,"chr12","-",24836447,24881398,"ENST00000612790",5,675,"ENSG00000060982","BCAT1","GO:0000082(G1/S transition of mitotic cell cycle);GO:0003824(catalytic activity);GO:0004084(branched-chain-amino-acid transaminase activity);GO:0005737(cytoplasm);GO:0005739(mitochondrion);GO:0005829(cytosol);GO:0008283(cell population proliferation);GO:0008483(transaminase activity);GO:0008652(cellular amino acid biosynthetic process);GO:0009081(branched-chain amino acid metabolic process);GO:0009082(branched-chain amino acid biosynthetic process);GO:0009083(branched-chain amino acid catabolic process);GO:0009098(leucine biosynthetic process);GO:0009099(valine biosynthetic process);GO:0016740(transferase activity);GO:0042802(identical protein binding);GO:0052654(L-leucine transaminase activity);GO:0052655(L-valine transaminase activity);GO:0052656(L-isoleucine transaminase activity)","00270(Cysteine and methionine metabolism);00280(Valine, leucine and isoleucine degradation);00290(Valine, leucine and isoleucine biosynthesis);00770(Pantothenate and CoA biosynthesis)","NA","NA","branched chain amino acid transaminase 1 [Source:HGNC Symbol;Acc:HGNC:976]",{"v":0.210446,"d":"0.21"},{"v":0.109675,"d":"0.11"},{"v":0.120015,"d":"0.12"},{"v":0.225246,"d":"0.23"},{"v":0.13253,"d":"0.13"},{"v":0.111816,"d":"0.11"},{"v":0.937273207380023,"d":"0.94"},{"v":-0.0934584520399743,"d":"-0.09"},1,1,"down","no"]
[20177,0,"chr10","-",31362799,31364049,"ENST00000649292",1,1251,"ENSG00000285781","AL117340","NA","NA","NA","NA","putative UPF0607 protein FLJ37424 [Source:NCBI gene;Acc:100505502]",{"v":0.067131,"d":"0.07"},{"v":0.070357,"d":"0.07"},{"v":0.112419,"d":"0.11"},{"v":0.083791,"d":"0.08"},{"v":0.012646,"d":"0.01"},{"v":0.108724,"d":"0.11"},{"v":1.21810188096178,"d":"1.22"},{"v":0.284634804025346,"d":"0.28"},1,1,"up","no"]
[163338,0,"chr5","-",139448560,139462743,"ENST00000618155",10,1031,"ENSG00000249751","ECSCR","GO:0001525(angiogenesis);GO:0005515(protein binding);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0006915(apoptotic process);GO:0006935(chemotaxis);GO:0007275(multicellular organism development);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016525(negative regulation of angiogenesis);GO:0030154(cell differentiation);GO:0043231(intracellular membrane-bounded organelle);GO:1901800(positive regulation of proteasomal protein catabolic process);GO:2000353(positive regulation of endothelial cell apoptotic process)","NA","NA","NA","endothelial cell surface expressed chemotaxis and apoptosis regulator [Source:HGNC Symbol;Acc:HGNC:35454]",0,{"v":0.08537,"d":"0.09"},0,0,0,0,"inf","inf",1,1,"up","no"]
[193711,0,"chr8","+",144082592,144083749,"ENST00000526341",4,557,"ENSG00000197858","GPAA1","GO:0003923(GPI-anchor transamidase activity);GO:0005515(protein binding);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0006506(GPI anchor biosynthetic process);GO:0006621(protein retention in ER lumen);GO:0015631(tubulin binding);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016255(attachment of GPI anchor to protein);GO:0034235(GPI anchor binding);GO:0042765(GPI-anchor transamidase complex);GO:0065003(protein-containing complex assembly)","00563(Glycosylphosphatidylinositol (GPI)-anchor biosynthesis)","K05289","NA","glycosylphosphatidylinositol anchor attachment 1 [Source:HGNC Symbol;Acc:HGNC:4446]",0,0,0,{"v":0.010899,"d":"0.01"},0,0,"-inf","-inf",1,1,"down","no"]
[13602,0,"chr1","-",165662775,165665206,"ENST00000463610",2,559,"ENSG00000143149","ALDH9A1","GO:0004029(aldehyde dehydrogenase (NAD) activity);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0006081(cellular aldehyde metabolic process);GO:0016491(oxidoreductase activity);GO:0016620(oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor);GO:0019145(aminobutyraldehyde dehydrogenase activity);GO:0033737(1-pyrroline dehydrogenase activity);GO:0042136(neurotransmitter biosynthetic process);GO:0042445(hormone metabolic process);GO:0043878(glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity);GO:0045329(carnitine biosynthetic process);GO:0047105(4-trimethylammoniobutyraldehyde dehydrogenase activity);GO:0055114(oxidation-reduction process);GO:0070062(extracellular exosome)","00010(Glycolysis / Gluconeogenesis);00053(Ascorbate and aldarate metabolism);00071(Fatty acid degradation);00280(Valine, leucine and isoleucine degradation);00310(Lysine degradation);00330(Arginine and proline metabolism);00340(Histidine metabolism);00380(Tryptophan metabolism);00410(beta-Alanine metabolism);00561(Glycerolipid metabolism);00620(Pyruvate metabolism)","NA","NA","aldehyde dehydrogenase 9 family member A1 [Source:HGNC Symbol;Acc:HGNC:412]",{"v":0.60883,"d":"0.61"},{"v":0.966611,"d":"0.97"},{"v":0.560058,"d":"0.56"},{"v":0.410043,"d":"0.41"},{"v":0.560733,"d":"0.56"},{"v":0.913047,"d":"0.91"},{"v":1.13359853871622,"d":"1.13"},{"v":0.180909803640071,"d":"0.18"},1,1,"up","no"]
[71967,0,"chr16","+",16317444,16318975,"ENST00000540039",3,571,"ENSG00000183889","AC138969","GO:0005654(nucleoplasm)","NA","NA","NA","novel member of the nuclear pore complex interacting protein NPIP gene family",{"v":0.130654,"d":"0.13"},0,{"v":0.126393,"d":"0.13"},{"v":0.353665,"d":"0.35"},{"v":0.1491,"d":"0.15"},{"v":0.10084,"d":"0.10"},{"v":0.425852999892314,"d":"0.43"},{"v":-1.23157258210162,"d":"-1.23"},1,1,"down","no"]
[161853,0,"chr5","-",116446464,116449646,"ENST00000503865",2,1678,"ENSG00000092421","SEMA6A","GO:0001755(neural crest cell migration);GO:0001764(neuron migration);GO:0004888(transmembrane signaling receptor activity);GO:0005515(protein binding);GO:0005615(extracellular space);GO:0005886(plasma membrane);GO:0005887(integral component of plasma membrane);GO:0006915(apoptotic process);GO:0007010(cytoskeleton organization);GO:0007166(cell surface receptor signaling pathway);GO:0007275(multicellular organism development);GO:0007399(nervous system development);GO:0007411(axon guidance);GO:0009887(animal organ morphogenesis);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016525(negative regulation of angiogenesis);GO:0030154(cell differentiation);GO:0030215(semaphorin receptor binding);GO:0030335(positive regulation of cell migration);GO:0030424(axon);GO:0035924(cellular response to vascular endothelial growth factor stimulus);GO:0045499(chemorepellent activity);GO:0048843(negative regulation of axon extension involved in axon guidance);GO:0050919(negative chemotaxis);GO:0051642(centrosome localization);GO:0070373(negative regulation of ERK1 and ERK2 cascade);GO:0071526(semaphorin-plexin signaling pathway);GO:0106089(negative regulation of cell adhesion involved in sprouting angiogenesis);GO:1900747(negative regulation of vascular endothelial growth factor signaling pathway);GO:1903671(negative regulation of sprouting angiogenesis);GO:2001224(positive regulation of neuron migration)","04360(Axon guidance)","K06842","NA","semaphorin 6A [Source:HGNC Symbol;Acc:HGNC:10738]",0,0,0,0,0,0,1,0,1,1,"no","no"]
[135231,0,"chr22","+",42269744,42279534,"ENST00000332965",2,5923,"ENSG00000182057","OGFRP1","NA","NA","NA","NA","opioid growth factor receptor pseudogene 1 [Source:HGNC Symbol;Acc:HGNC:50511]",{"v":0.133276,"d":"0.13"},0,0,0,{"v":0.196507,"d":"0.20"},0,{"v":0.678225203173424,"d":"0.68"},{"v":-0.560163698289105,"d":"-0.56"},1,1,"down","no"]
[109114,0,"chr19","+",58467056,58475436,"ENST00000536459",4,5653,"ENSG00000083812","ZNF324","GO:0000981(DNA-binding transcription factor activity, RNA polymerase II-specific);GO:0003676(nucleic acid binding);GO:0003677(DNA binding);GO:0005622(intracellular);GO:0005634(nucleus);GO:0006355(regulation of transcription, DNA-templated);GO:0006357(regulation of transcription by RNA polymerase II);GO:0046872(metal ion binding)","05168(Herpes simplex virus 1 infection)","K09228","NA","zinc finger protein 324 [Source:HGNC Symbol;Acc:HGNC:14096]",{"v":0.036847,"d":"0.04"},{"v":0.006825,"d":"0.01"},0,{"v":0.006747,"d":"0.01"},{"v":0.027921,"d":"0.03"},{"v":0.007844,"d":"0.01"},{"v":1.02728641324802,"d":"1.03"},{"v":0.0388384692559104,"d":"0.04"},1,1,"up","no"]
[48035,0,"chr12","-",111443485,111599122,"ENST00000642389",27,4438,"ENSG00000204842","ATXN2","GO:0002091(negative regulation of receptor internalization);GO:0003723(RNA binding);GO:0005154(epidermal growth factor receptor binding);GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0005794(Golgi apparatus);GO:0005802(trans-Golgi network);GO:0005829(cytosol);GO:0005844(polysome);GO:0006417(regulation of translation);GO:0008022(protein C-terminus binding);GO:0010494(cytoplasmic stress granule);GO:0010603(regulation of cytoplasmic mRNA processing body assembly);GO:0016020(membrane);GO:0016070(RNA metabolic process);GO:0033962(cytoplasmic mRNA processing body assembly);GO:0034063(stress granule assembly);GO:0048471(perinuclear region of cytoplasm);GO:0050658(RNA transport);GO:1990904(ribonucleoprotein complex)","NA","NA","NA","ataxin 2 [Source:HGNC Symbol;Acc:HGNC:10555]",{"v":0.043538,"d":"0.04"},{"v":0.034023,"d":"0.03"},{"v":0.034025,"d":"0.03"},{"v":0.058875,"d":"0.06"},0,0,{"v":1.89530360934183,"d":"1.90"},{"v":0.92242897272724,"d":"0.92"},1,1,"up","no"]
[16641,0,"chr1","-",220200546,220200676,"ENST00000410438",1,131,"ENSG00000222370","SNORA36B","NA","NA","NA","NA","small nucleolar RNA, H/ACA box 36B [Source:HGNC Symbol;Acc:HGNC:32629]",{"v":0.100026,"d":"0.10"},0,0,0,0,0,"inf","inf",1,1,"up","no"]
[188248,0,"chr8","+",35235475,35796540,"ENST00000404895",17,9149,"ENSG00000156687","UNC5D","GO:0005042(netrin receptor activity);GO:0005515(protein binding);GO:0005886(plasma membrane);GO:0006915(apoptotic process);GO:0007165(signal transduction);GO:0007275(multicellular organism development);GO:0007411(axon guidance);GO:0009986(cell surface);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0021859(pyramidal neuron differentiation);GO:0038007(netrin-activated signaling pathway);GO:0098742(cell-cell adhesion via plasma-membrane adhesion molecules);GO:2001222(regulation of neuron migration)","04360(Axon guidance)","K07521","NA","unc-5 netrin receptor D [Source:HGNC Symbol;Acc:HGNC:18634]",{"v":0.004525,"d":"0.00"},{"v":0.002405,"d":"0.00"},0,0,0,{"v":0.009693,"d":"0.01"},{"v":0.714948932219127,"d":"0.71"},{"v":-0.484087898961944,"d":"-0.48"},1,1,"down","no"]
[146944,0,"chr3","+",181461584,181611647,"ENST00000644304",3,1115,"ENSG00000242808","SOX2-OT","NA","NA","NA","NA","SOX2 overlapping transcript [Source:HGNC Symbol;Acc:HGNC:20209]",0,0,0,0,0,0,1,0,1,1,"no","no"]
[35108,0,"chr11","-",88326086,88328198,"ENST00000528020",2,401,"ENSG00000109861","CTSC","GO:0000139(Golgi membrane);GO:0001913(T cell mediated cytotoxicity);GO:0004197(cysteine-type endopeptidase activity);GO:0004252(serine-type endopeptidase activity);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0005615(extracellular space);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0005764(lysosome);GO:0005783(endoplasmic reticulum);GO:0005788(endoplasmic reticulum lumen);GO:0005794(Golgi apparatus);GO:0005813(centrosome);GO:0006508(proteolysis);GO:0006888(endoplasmic reticulum to Golgi vesicle-mediated transport);GO:0006915(apoptotic process);GO:0006955(immune response);GO:0007568(aging);GO:0008233(peptidase activity);GO:0008234(cysteine-type peptidase activity);GO:0010033(response to organic substance);GO:0016020(membrane);GO:0016505(peptidase activator activity involved in apoptotic process);GO:0016787(hydrolase activity);GO:0019902(phosphatase binding);GO:0030134(COPII-coated ER to Golgi transport vesicle);GO:0031404(chloride ion binding);GO:0031642(negative regulation of myelination);GO:0033116(endoplasmic reticulum-Golgi intermediate compartment membrane);GO:0035578(azurophil granule lumen);GO:0042802(identical protein binding);GO:0043231(intracellular membrane-bounded organelle);GO:0043312(neutrophil degranulation);GO:0043621(protein self-association);GO:0048208(COPII vesicle coating);GO:0051087(chaperone binding);GO:0051603(proteolysis involved in cellular protein catabolic process);GO:0062023(collagen-containing extracellular matrix);GO:0070062(extracellular exosome);GO:1903052(positive regulation of proteolysis involved in cellular protein catabolic process);GO:1903980(positive regulation of microglial cell activation);GO:2001235(positive regulation of apoptotic signaling pathway)","04142(Lysosome);04210(Apoptosis)","NA","NA","cathepsin C [Source:HGNC Symbol;Acc:HGNC:2528]",{"v":0.007903,"d":"0.01"},{"v":0.010195,"d":"0.01"},{"v":0.016575,"d":"0.02"},{"v":0.008045,"d":"0.01"},{"v":0.010642,"d":"0.01"},{"v":0.013987,"d":"0.01"},{"v":1.06118014323315,"d":"1.06"},{"v":0.0856695852711406,"d":"0.09"},1,1,"up","no"]
[50268,0,"chr13","-",19563589,19564900,"ENST00000456608",1,1312,"ENSG00000238132","CASC4P1","NA","NA","NA","NA","cancer susceptibility 4 pseudogene 1 [Source:HGNC Symbol;Acc:HGNC:39251]",0,{"v":0.015463,"d":"0.02"},{"v":0.019965,"d":"0.02"},0,0,0,"inf","inf",1,1,"up","no"]
[20745,0,"chr10","-",45854093,45892483,"ENST00000440803",5,790,"ENSG00000239883","PARGP1","NA","NA","NA","NA","poly(ADP-ribose) glycohydrolase pseudogene 1 [Source:HGNC Symbol;Acc:HGNC:45008]",{"v":0.540075,"d":"0.54"},0,{"v":0.565694,"d":"0.57"},{"v":0.316023,"d":"0.32"},{"v":0.562641,"d":"0.56"},{"v":0.327337,"d":"0.33"},{"v":0.916888957803518,"d":"0.92"},{"v":-0.125181071782977,"d":"-0.13"},1,1,"down","no"]
[10500,0,"chr1","+",147242677,147295724,"ENST00000650721",22,2862,"ENSG00000131778","CHD1L","GO:0000166(nucleotide binding);GO:0000717(nucleotide-excision repair, DNA duplex unwinding);GO:0004003(ATP-dependent DNA helicase activity);GO:0004386(helicase activity);GO:0005515(protein binding);GO:0005524(ATP binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0006281(DNA repair);GO:0006293(nucleotide-excision repair, preincision complex stabilization);GO:0006294(nucleotide-excision repair, preincision complex assembly);GO:0006295(nucleotide-excision repair, DNA incision, 3'-to lesion);GO:0006296(nucleotide-excision repair, DNA incision, 5'-to lesion);GO:0006338(chromatin remodeling);GO:0006974(cellular response to DNA damage stimulus);GO:0016787(hydrolase activity);GO:0016887(ATPase activity);GO:0032508(DNA duplex unwinding);GO:0033683(nucleotide-excision repair, DNA incision);GO:0043044(ATP-dependent chromatin remodeling);GO:0070911(global genome nucleotide-excision repair)","NA","K20092","EC:3.6.4.12","chromodomain helicase DNA binding protein 1 like [Source:HGNC Symbol;Acc:HGNC:1916]",0,0,{"v":0.143251,"d":"0.14"},{"v":0.194728,"d":"0.19"},{"v":0.118896,"d":"0.12"},{"v":0.056175,"d":"0.06"},{"v":0.387375303881298,"d":"0.39"},{"v":-1.36819611333565,"d":"-1.37"},1,1,"down","no"]
[92086,0,"chr17","-",82244722,82245113,"ENST00000584913",2,295,"ENSG00000141551","CSNK1D","GO:0000086(G2/M transition of mitotic cell cycle);GO:0000139(Golgi membrane);GO:0000166(nucleotide binding);GO:0001934(positive regulation of protein phosphorylation);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005515(protein binding);GO:0005524(ATP binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0005794(Golgi apparatus);GO:0005813(centrosome);GO:0005815(microtubule organizing center);GO:0005819(spindle);GO:0005829(cytosol);GO:0005856(cytoskeleton);GO:0005876(spindle microtubule);GO:0005886(plasma membrane);GO:0006468(protein phosphorylation);GO:0007020(microtubule nucleation);GO:0007030(Golgi organization);GO:0010389(regulation of G2/M transition of mitotic cell cycle);GO:0016020(membrane);GO:0016055(Wnt signaling pathway);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0016740(transferase activity);GO:0018105(peptidyl-serine phosphorylation);GO:0018107(peptidyl-threonine phosphorylation);GO:0030177(positive regulation of Wnt signaling pathway);GO:0032436(positive regulation of proteasomal ubiquitin-dependent protein catabolic process);GO:0032922(circadian regulation of gene expression);GO:0033116(endoplasmic reticulum-Golgi intermediate compartment membrane);GO:0034067(protein localization to Golgi apparatus);GO:0042752(regulation of circadian rhythm);GO:0043005(neuron projection);GO:0045296(cadherin binding);GO:0048208(COPII vesicle coating);GO:0048471(perinuclear region of cytoplasm);GO:0048511(rhythmic process);GO:0050321(tau-protein kinase activity);GO:0051225(spindle assembly);GO:0061512(protein localization to cilium);GO:0071539(protein localization to centrosome);GO:0090263(positive regulation of canonical Wnt signaling pathway);GO:0097711(ciliary basal body-plasma membrane docking);GO:1905426(positive regulation of Wnt-mediated midbrain dopaminergic neuron differentiation);GO:1905515(non-motile cilium assembly);GO:1990090(cellular response to nerve growth factor stimulus);GO:2000052(positive regulation of non-canonical Wnt signaling pathway)","04340(Hedgehog signaling pathway);04390(Hippo signaling pathway);04540(Gap junction);04710(Circadian rhythm)","NA","NA","casein kinase 1 delta [Source:HGNC Symbol;Acc:HGNC:2452]",{"v":0.294954,"d":"0.29"},{"v":0.411817,"d":"0.41"},{"v":1.146015,"d":"1.15"},{"v":0.37705,"d":"0.38"},{"v":0.335555,"d":"0.34"},{"v":0.166181,"d":"0.17"},{"v":2.10834719715608,"d":"2.11"},{"v":1.07611246582218,"d":"1.08"},1,1,"up","no"]
[159470,0,"chr5","+",65722243,65829283,"ENST00000502464",12,8354,"ENSG00000123213","NLN","GO:0004222(metalloendopeptidase activity);GO:0005576(extracellular region);GO:0005737(cytoplasm);GO:0005739(mitochondrion);GO:0005758(mitochondrial intermembrane space);GO:0005886(plasma membrane);GO:0006111(regulation of gluconeogenesis);GO:0006508(proteolysis);GO:0006518(peptide metabolic process);GO:0008233(peptidase activity);GO:0008237(metallopeptidase activity);GO:0016787(hydrolase activity);GO:0042277(peptide binding);GO:0046872(metal ion binding);GO:1902809(regulation of skeletal muscle fiber differentiation)","04614(Renin-angiotensin system)","K01393","EC:3.4.24.16","neurolysin [Source:HGNC Symbol;Acc:HGNC:16058]",0,0,0,0,0,{"v":0.419473,"d":"0.42"},"-inf","-inf",1,1,"down","no"]
[78337,0,"chr16","+",84699986,84745211,"ENST00000562743",5,888,"ENSG00000103194","USP10","GO:0002039(p53 binding);GO:0003723(RNA binding);GO:0004197(cysteine-type endopeptidase activity);GO:0004843(thiol-dependent ubiquitin-specific protease activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0005768(endosome);GO:0005769(early endosome);GO:0005829(cytosol);GO:0006281(DNA repair);GO:0006508(proteolysis);GO:0006511(ubiquitin-dependent protein catabolic process);GO:0006914(autophagy);GO:0006974(cellular response to DNA damage stimulus);GO:0008233(peptidase activity);GO:0008234(cysteine-type peptidase activity);GO:0010506(regulation of autophagy);GO:0016579(protein deubiquitination);GO:0016787(hydrolase activity);GO:0019985(translesion synthesis);GO:0030330(DNA damage response, signal transduction by p53 class mediator);GO:0032991(protein-containing complex);GO:0036459(thiol-dependent ubiquitinyl hydrolase activity);GO:0043124(negative regulation of I-kappaB kinase/NF-kappaB signaling);GO:0044325(ion channel binding);GO:0071347(cellular response to interleukin-1)","NA","K11841","EC:3.4.19.12","ubiquitin specific peptidase 10 [Source:HGNC Symbol;Acc:HGNC:12608]",{"v":0.009661,"d":"0.01"},0,0,{"v":0.0089,"d":"0.01"},0,0,{"v":1.08550561797753,"d":"1.09"},{"v":0.118367192565076,"d":"0.12"},1,1,"up","no"]
[85673,0,"chr17","+",42289213,42292037,"ENST00000478897",3,550,"ENSG00000126561","STAT5A","GO:0000981(DNA-binding transcription factor activity, RNA polymerase II-specific);GO:0001938(positive regulation of endothelial cell proliferation);GO:0003677(DNA binding);GO:0003700(DNA-binding transcription factor activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0006355(regulation of transcription, DNA-templated);GO:0006357(regulation of transcription by RNA polymerase II);GO:0007165(signal transduction);GO:0007259(receptor signaling pathway via JAK-STAT);GO:0007595(lactation);GO:0019221(cytokine-mediated signaling pathway);GO:0019530(taurine metabolic process);GO:0035723(interleukin-15-mediated signaling pathway);GO:0038026(reelin-mediated signaling pathway);GO:0038110(interleukin-2-mediated signaling pathway);GO:0038111(interleukin-7-mediated signaling pathway);GO:0038113(interleukin-9-mediated signaling pathway);GO:0040014(regulation of multicellular organism growth);GO:0043536(positive regulation of blood vessel endothelial cell migration);GO:0060397(growth hormone receptor signaling pathway via JAK-STAT)","04012(ErbB signaling pathway);04217(Necroptosis);04630(Jak-STAT signaling pathway);04658(Th1 and Th2 cell differentiation);04659(Th17 cell differentiation);04917(Prolactin signaling pathway);04933(AGE-RAGE signaling pathway in diabetic complications);05161(Hepatitis B);05162(Measles);05166(Human T-cell leukemia virus 1 infection);05200(Pathways in cancer);05203(Viral carcinogenesis);05220(Chronic myeloid leukemia);05221(Acute myeloid leukemia);05223(Non-small cell lung cancer)","K11223","NA","signal transducer and activator of transcription 5A [Source:HGNC Symbol;Acc:HGNC:11366]",{"v":0.099919,"d":"0.10"},{"v":0.082586,"d":"0.08"},{"v":0.252199,"d":"0.25"},{"v":0.035312,"d":"0.04"},{"v":0.073975,"d":"0.07"},{"v":0.016451,"d":"0.02"},{"v":3.45722056975616,"d":"3.46"},{"v":1.7896126500979,"d":"1.79"},1,1,"up","no"]
[90533,0,"chr17","-",75920273,75923473,"ENST00000586838",5,745,"ENSG00000188878","FBF1","GO:0000922(spindle pole);GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0005813(centrosome);GO:0005814(centriole);GO:0005829(cytosol);GO:0005856(cytoskeleton);GO:0030030(cell projection organization);GO:0030054(cell junction);GO:0043296(apical junction complex);GO:0043297(apical junction assembly);GO:0045095(keratin filament);GO:0060271(cilium assembly);GO:0090162(establishment of epithelial cell polarity);GO:0097539(ciliary transition fiber);GO:0097711(ciliary basal body-plasma membrane docking)","NA","K16471","NA","Fas binding factor 1 [Source:HGNC Symbol;Acc:HGNC:24674]",0,0,0,0,0,{"v":0.112948,"d":"0.11"},"-inf","-inf",1,1,"down","no"]
[81742,0,"chr17","-",15267461,15272290,"ENST00000431343",2,1773,"ENSG00000230971","AC005703","NA","NA","NA","NA","novel transcript",0,{"v":0.059475,"d":"0.06"},0,0,0,0,"inf","inf",1,1,"up","no"]
[41296,0,"chr12","+",29389738,29464741,"ENST00000550906",3,654,"ENSG00000257599","OVCH1-AS1","NA","NA","NA","NA","OVCH1 antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:44484]",0,{"v":0.083169,"d":"0.08"},0,0,0,0,"inf","inf",1,1,"up","no"]
[101868,0,"chr19","+",27793483,27798282,"ENST00000586784",2,656,"ENSG00000267575","AC006504","NA","NA","NA","NA","novel transcript",{"v":0.153595,"d":"0.15"},{"v":0.491613,"d":"0.49"},{"v":0.061875,"d":"0.06"},{"v":0.717609,"d":"0.72"},{"v":0.182857,"d":"0.18"},0,{"v":0.785241197335602,"d":"0.79"},{"v":-0.348792229734039,"d":"-0.35"},1,1,"down","no"]
[87972,0,"chr17","+",54936413,54937484,"ENST00000570623",2,673,"ENSG00000141198","TOM1L1","GO:0005515(protein binding);GO:0005622(intracellular);GO:0005623(cell);GO:0005737(cytoplasm);GO:0005764(lysosome);GO:0005768(endosome);GO:0005794(Golgi apparatus);GO:0005795(Golgi stack);GO:0005829(cytosol);GO:0006886(intracellular protein transport);GO:0007165(signal transduction);GO:0010008(endosome membrane);GO:0015031(protein transport);GO:0016020(membrane);GO:0017124(SH3 domain binding);GO:0019901(protein kinase binding);GO:0030276(clathrin binding);GO:0030295(protein kinase activator activity);GO:0031954(positive regulation of protein autophosphorylation);GO:0032147(activation of protein kinase activity);GO:0043130(ubiquitin binding);GO:0043162(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway);GO:0045839(negative regulation of mitotic nuclear division);GO:0070062(extracellular exosome)","NA","NA","NA","target of myb1 like 1 membrane trafficking protein [Source:HGNC Symbol;Acc:HGNC:11983]",{"v":0.079036,"d":"0.08"},{"v":0.149169,"d":"0.15"},{"v":0.145538,"d":"0.15"},{"v":0.140094,"d":"0.14"},{"v":0.313358,"d":"0.31"},{"v":0.12819,"d":"0.13"},{"v":0.642565358072491,"d":"0.64"},{"v":-0.638084890430663,"d":"-0.64"},1,1,"down","no"]
[151546,0,"chr4","+",56436138,56461361,"ENST00000399688",10,3297,"ENSG00000128050","PAICS","GO:0000166(nucleotide binding);GO:0003824(catalytic activity);GO:0004638(phosphoribosylaminoimidazole carboxylase activity);GO:0004639(phosphoribosylaminoimidazolesuccinocarboxamide synthase activity);GO:0005515(protein binding);GO:0005524(ATP binding);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0006164(purine nucleotide biosynthetic process);GO:0006189('de novo' IMP biosynthetic process);GO:0008152(metabolic process);GO:0009113(purine nucleobase biosynthetic process);GO:0009168(purine ribonucleoside monophosphate biosynthetic process);GO:0016020(membrane);GO:0016829(lyase activity);GO:0016831(carboxy-lyase activity);GO:0016874(ligase activity);GO:0042802(identical protein binding);GO:0043727(5-amino-4-imidazole carboxylate lyase activity);GO:0045296(cadherin binding);GO:0070062(extracellular exosome)","00230(Purine metabolism)","K01587","6.3.2.6;EC:4.1.1.21","phosphoribosylaminoimidazole carboxylase and phosphoribosylaminoimidazolesuccinocarboxamide synthase [Source:HGNC Symbol;Acc:HGNC:8587]",{"v":0.194557,"d":"0.19"},{"v":0.530546,"d":"0.53"},0,{"v":0.111879,"d":"0.11"},0,0,{"v":6.48113587000241,"d":"6.48"},{"v":2.69624667891429,"d":"2.70"},1,1,"up","no"]
[193805,0,"chr8","-",144330565,144336482,"ENST00000569446",2,3980,"ENSG00000261678","SCRT1","GO:0000122(negative regulation of transcription by RNA polymerase II);GO:0000977(RNA polymerase II regulatory region sequence-specific DNA binding);GO:0000981(DNA-binding transcription factor activity, RNA polymerase II-specific);GO:0001227(DNA-binding transcription repressor activity, RNA polymerase II-specific);GO:0003676(nucleic acid binding);GO:0003677(DNA binding);GO:0003700(DNA-binding transcription factor activity);GO:0005634(nucleus);GO:0006355(regulation of transcription, DNA-templated);GO:0016604(nuclear body);GO:0043565(sequence-specific DNA binding);GO:0046872(metal ion binding);GO:2001222(regulation of neuron migration)","NA","K09219","NA","scratch family transcriptional repressor 1 [Source:HGNC Symbol;Acc:HGNC:15950]",0,{"v":0.027017,"d":"0.03"},0,{"v":0.010527,"d":"0.01"},0,{"v":0.016198,"d":"0.02"},{"v":1.01092609915809,"d":"1.01"},{"v":0.0156775370282814,"d":"0.02"},1,1,"up","no"]
[150037,0,"chr4","+",15479216,15540276,"ENST00000651385",15,3427,"ENSG00000048342","CC2D2A","GO:0001843(neural tube closure);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005856(cytoskeleton);GO:0005929(cilium);GO:0007224(smoothened signaling pathway);GO:0007368(determination of left/right symmetry);GO:0007507(heart development);GO:0030030(cell projection organization);GO:0035082(axoneme assembly);GO:0035869(ciliary transition zone);GO:0036038(MKS complex);GO:0042995(cell projection);GO:0043010(camera-type eye development);GO:0044458(motile cilium assembly);GO:0060271(cilium assembly);GO:0097711(ciliary basal body-plasma membrane docking);GO:1904491(protein localization to ciliary transition zone);GO:1905515(non-motile cilium assembly);GO:1990403(embryonic brain development)","NA","K19352","NA","coiled-coil and C2 domain containing 2A [Source:HGNC Symbol;Acc:HGNC:29253]",{"v":0.012253,"d":"0.01"},{"v":0.012842,"d":"0.01"},{"v":0.054778,"d":"0.05"},{"v":0.018376,"d":"0.02"},{"v":0.015084,"d":"0.02"},{"v":0.038665,"d":"0.04"},{"v":1.10742461005199,"d":"1.11"},{"v":0.14720848802976,"d":"0.15"},1,1,"up","no"]
[8771,0,"chr1","+",101238090,101241372,"ENST00000475289",2,2713,"ENSG00000170989","S1PR1","GO:0001525(angiogenesis);GO:0001664(G protein-coupled receptor binding);GO:0001955(blood vessel maturation);GO:0003245(cardiac muscle tissue growth involved in heart morphogenesis);GO:0003376(sphingosine-1-phosphate receptor signaling pathway);GO:0004930(G protein-coupled receptor activity);GO:0005515(protein binding);GO:0005654(nucleoplasm);GO:0005768(endosome);GO:0005886(plasma membrane);GO:0006935(chemotaxis);GO:0007155(cell adhesion);GO:0007165(signal transduction);GO:0007186(G protein-coupled receptor signaling pathway);GO:0007193(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway);GO:0007420(brain development);GO:0008284(positive regulation of cell population proliferation);GO:0009897(external side of plasma membrane);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016477(cell migration);GO:0019221(cytokine-mediated signaling pathway);GO:0019226(transmission of nerve impulse);GO:0030032(lamellipodium assembly);GO:0030155(regulation of cell adhesion);GO:0030182(neuron differentiation);GO:0030335(positive regulation of cell migration);GO:0030500(regulation of bone mineralization);GO:0030595(leukocyte chemotaxis);GO:0031226(intrinsic component of plasma membrane);GO:0031532(actin cytoskeleton reorganization);GO:0038036(sphingosine-1-phosphate receptor activity);GO:0043231(intracellular membrane-bounded organelle);GO:0043547(positive regulation of GTPase activity);GO:0045121(membrane raft);GO:0045124(regulation of bone resorption);GO:0045446(endothelial cell differentiation);GO:0045944(positive regulation of transcription by RNA polymerase II);GO:0046625(sphingolipid binding);GO:0048661(positive regulation of smooth muscle cell proliferation);GO:0050927(positive regulation of positive chemotaxis);GO:0051482(positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway);GO:0051497(negative regulation of stress fiber assembly);GO:0061384(heart trabecula morphogenesis);GO:0072678(T cell migration)","04068(FoxO signaling pathway);04071(Sphingolipid signaling pathway);04080(Neuroactive ligand-receptor interaction)","K04288","NA","sphingosine-1-phosphate receptor 1 [Source:HGNC Symbol;Acc:HGNC:3165]",{"v":0.007739,"d":"0.01"},{"v":2.240546,"d":"2.24"},0,0,{"v":0.009561,"d":"0.01"},{"v":0.024516,"d":"0.02"},{"v":65.976611790944,"d":"65.98"},{"v":6.04388278552262,"d":"6.04"},1,1,"up","no"]
[29414,0,"chr11","+",44096223,44245425,"ENST00000343631",14,3424,"ENSG00000151348","EXT2","GO:0000139(Golgi membrane);GO:0001503(ossification);GO:0001707(mesoderm formation);GO:0005515(protein binding);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005794(Golgi apparatus);GO:0006024(glycosaminoglycan biosynthetic process);GO:0006486(protein glycosylation);GO:0007165(signal transduction);GO:0008375(acetylglucosaminyltransferase activity);GO:0015012(heparan sulfate proteoglycan biosynthetic process);GO:0015014(heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process);GO:0015020(glucuronosyltransferase activity);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016740(transferase activity);GO:0016757(transferase activity, transferring glycosyl groups);GO:0030154(cell differentiation);GO:0033692(cellular polysaccharide biosynthetic process);GO:0042328(heparan sulfate N-acetylglucosaminyltransferase activity);GO:0043541(UDP-N-acetylglucosamine transferase complex);GO:0046872(metal ion binding);GO:0046982(protein heterodimerization activity);GO:0050508(glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity);GO:0050509(N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity);GO:0070062(extracellular exosome)","00534(Glycosaminoglycan biosynthesis - heparan sulfate / heparin)","K02367","2.4.1.225;EC:2.4.1.224","exostosin glycosyltransferase 2 [Source:HGNC Symbol;Acc:HGNC:3513]",0,0,0,0,0,0,1,0,1,1,"no","no"]
[96562,0,"chr19","+",1267229,1274480,"ENST00000591935",7,746,"ENSG00000099622","CIRBP","GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0003730(mRNA 3'-UTR binding);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005681(spliceosomal complex);GO:0005730(nucleolus);GO:0005737(cytoplasm);GO:0008266(poly(U) RNA binding);GO:0009409(response to cold);GO:0009411(response to UV);GO:0010494(cytoplasmic stress granule);GO:0017148(negative regulation of translation);GO:0030371(translation repressor activity);GO:0034063(stress granule assembly);GO:0045727(positive regulation of translation);GO:0048026(positive regulation of mRNA splicing, via spliceosome);GO:0048255(mRNA stabilization);GO:0070181(small ribosomal subunit rRNA binding);GO:1990904(ribonucleoprotein complex)","NA","NA","NA","cold inducible RNA binding protein [Source:HGNC Symbol;Acc:HGNC:1982]",0,{"v":0.374648,"d":"0.37"},{"v":0.509408,"d":"0.51"},{"v":0.393605,"d":"0.39"},{"v":0.386883,"d":"0.39"},{"v":0.58999,"d":"0.59"},{"v":0.645071281698794,"d":"0.65"},{"v":-0.632469504783632,"d":"-0.63"},1,1,"down","no"]
[161157,0,"chr5","+",95852232,95859020,"ENST00000357880",3,804,"ENSG00000236882","LINC01554","NA","NA","NA","NA","long intergenic non-protein coding RNA 1554 [Source:HGNC Symbol;Acc:HGNC:24687]",0,0,0,0,0,0,1,0,1,1,"no","no"]
[169497,0,"chr6","-",32168212,32173115,"ENST00000395496",7,2103,"ENSG00000204310","AGPAT1","GO:0001819(positive regulation of cytokine production);GO:0001961(positive regulation of cytokine-mediated signaling pathway);GO:0003841(1-acylglycerol-3-phosphate O-acyltransferase activity);GO:0005515(protein binding);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0006629(lipid metabolic process);GO:0006644(phospholipid metabolic process);GO:0006654(phosphatidic acid biosynthetic process);GO:0008654(phospholipid biosynthetic process);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016024(CDP-diacylglycerol biosynthetic process);GO:0016740(transferase activity);GO:0016746(transferase activity, transferring acyl groups);GO:0031325(positive regulation of cellular metabolic process)","00561(Glycerolipid metabolism);00564(Glycerophospholipid metabolism);04072(Phospholipase D signaling pathway);04975(Fat digestion and absorption)","K13509","EC:2.3.1.51","1-acylglycerol-3-phosphate O-acyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:324]",{"v":0.019704,"d":"0.02"},{"v":0.015048,"d":"0.02"},0,0,0,0,"inf","inf",1,1,"up","no"]
[82729,0,"chr17","-",19411786,19413118,"ENST00000579897",2,567,"ENSG00000265126","AC004448","NA","NA","NA","NA","novel transcript, antisense to RNF112",{"v":0.209088,"d":"0.21"},{"v":0.316664,"d":"0.32"},{"v":0.287163,"d":"0.29"},{"v":0.359073,"d":"0.36"},{"v":0.255405,"d":"0.26"},{"v":0.521872,"d":"0.52"},{"v":0.715373784485414,"d":"0.72"},{"v":-0.483230844440541,"d":"-0.48"},1,1,"down","no"]
[1865,0,"chr1","+",15305762,15330059,"ENST00000375997",8,1459,"ENSG00000142621","FHAD1","GO:0005515(protein binding)","NA","NA","NA","forkhead associated phosphopeptide binding domain 1 [Source:HGNC Symbol;Acc:HGNC:29408]",0,{"v":0.044074,"d":"0.04"},0,0,0,0,"inf","inf",1,1,"up","no"]
[184633,0,"chr7","-",141704338,141738230,"ENST00000488785",7,2262,"ENSG00000228775","WEE2-AS1","NA","NA","NA","NA","WEE2 antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:48669]",{"v":0.306207,"d":"0.31"},{"v":0.327728,"d":"0.33"},{"v":0.334568,"d":"0.33"},{"v":0.243618,"d":"0.24"},{"v":0.176492,"d":"0.18"},{"v":0.015973,"d":"0.02"},{"v":2.22091436721908,"d":"2.22"},{"v":1.15115376732431,"d":"1.15"},1,1,"up","no"]
[43064,0,"chr12","+",51900565,51901336,"ENST00000552112",1,772,"ENSG00000258021","AC025259","NA","NA","NA","NA","filamin B, beta (FLNB) pseudogene",0,{"v":0.056197,"d":"0.06"},{"v":0.05554,"d":"0.06"},{"v":0.026268,"d":"0.03"},{"v":0.096746,"d":"0.10"},0,{"v":0.908327507438178,"d":"0.91"},{"v":-0.138715524061321,"d":"-0.14"},1,1,"down","no"]
[34227,0,"chr11","-",74830574,74832510,"ENST00000624150",1,1937,"ENSG00000278879","AP000560","NA","NA","NA","NA","TEC",{"v":0.021678,"d":"0.02"},{"v":0.204316,"d":"0.20"},{"v":0.022699,"d":"0.02"},{"v":0.043416,"d":"0.04"},{"v":0.006363,"d":"0.01"},0,{"v":4.99594206392254,"d":"5.00"},{"v":2.32075674664637,"d":"2.32"},1,1,"up","no"]
[107637,0,"chr19","+",53395144,53427321,"ENST00000504235",8,2059,"ENSG00000196417","ZNF765","GO:0000981(DNA-binding transcription factor activity, RNA polymerase II-specific);GO:0003676(nucleic acid binding);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0005622(intracellular);GO:0005634(nucleus);GO:0006355(regulation of transcription, DNA-templated);GO:0006357(regulation of transcription by RNA polymerase II);GO:0046872(metal ion binding)","05168(Herpes simplex virus 1 infection)","K09228","NA","zinc finger protein 765 [Source:HGNC Symbol;Acc:HGNC:25092]",{"v":0.218133,"d":"0.22"},{"v":0.18442,"d":"0.18"},{"v":0.303399,"d":"0.30"},{"v":0.142607,"d":"0.14"},{"v":0.372386,"d":"0.37"},{"v":0.245184,"d":"0.25"},{"v":0.928667928653458,"d":"0.93"},{"v":-0.106765282271385,"d":"-0.11"},1,1,"down","no"]
[186542,0,"chr8","-",11315859,11325429,"ENST00000498997",2,5856,"ENSG00000246477","AF131216","NA","NA","NA","NA","novel transcript, antisense to MTMR9",{"v":0.046532,"d":"0.05"},{"v":0.037619,"d":"0.04"},{"v":0.051286,"d":"0.05"},{"v":0.030797,"d":"0.03"},{"v":0.026576,"d":"0.03"},{"v":0.033195,"d":"0.03"},{"v":1.49541780761417,"d":"1.50"},{"v":0.580548618042631,"d":"0.58"},1,1,"up","no"]
[92170,0,"chr17","-",82443823,82450770,"ENST00000585064",7,1074,"ENSG00000178927","CYBC1","GO:0002376(immune system process);GO:0005515(protein binding);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0045087(innate immune response);GO:0045728(respiratory burst after phagocytosis)","NA","NA","NA","cytochrome b-245 chaperone 1 [Source:HGNC Symbol;Acc:HGNC:28672]",{"v":0.497448,"d":"0.50"},{"v":0.115536,"d":"0.12"},{"v":1.547617,"d":"1.55"},{"v":0.393426,"d":"0.39"},{"v":0.420713,"d":"0.42"},{"v":0.294409,"d":"0.29"},{"v":1.94903693840952,"d":"1.95"},{"v":0.962761433004857,"d":"0.96"},1,1,"up","no"]
[27393,0,"chr11","-",9022552,9025821,"ENST00000532532",2,325,"ENSG00000175356","SCUBE2","GO:0005509(calcium ion binding);GO:0005576(extracellular region);GO:0005615(extracellular space);GO:0007275(multicellular organism development);GO:0008289(lipid binding);GO:0009986(cell surface)","NA","NA","NA","signal peptide, CUB domain and EGF like domain containing 2 [Source:HGNC Symbol;Acc:HGNC:30425]",{"v":0.069753,"d":"0.07"},{"v":0.13541,"d":"0.14"},{"v":0.2384,"d":"0.24"},0,{"v":0.019811,"d":"0.02"},{"v":0.076419,"d":"0.08"},{"v":4.60940455159514,"d":"4.61"},{"v":2.20458039361665,"d":"2.20"},1,1,"up","no"]
[33331,0,"chr11","-",68267180,68271916,"ENST00000532534",3,687,"ENSG00000171067","C11orf24","GO:0005794(Golgi apparatus);GO:0005886(plasma membrane);GO:0016020(membrane);GO:0016021(integral component of membrane)","NA","NA","NA","chromosome 11 open reading frame 24 [Source:HGNC Symbol;Acc:HGNC:1174]",{"v":0.251021,"d":"0.25"},{"v":0.527614,"d":"0.53"},{"v":0.062496,"d":"0.06"},{"v":0.284495,"d":"0.28"},{"v":0.150917,"d":"0.15"},{"v":0.356015,"d":"0.36"},{"v":1.06280301278577,"d":"1.06"},{"v":0.0878742226333061,"d":"0.09"},1,1,"up","no"]
[39245,0,"chr12","-",6673060,6678542,"ENST00000542519",2,797,"ENSG00000126746","ZNF384","GO:0000981(DNA-binding transcription factor activity, RNA polymerase II-specific);GO:0003676(nucleic acid binding);GO:0003677(DNA binding);GO:0005634(nucleus);GO:0006357(regulation of transcription by RNA polymerase II);GO:0046872(metal ion binding)","NA","NA","NA","zinc finger protein 384 [Source:HGNC Symbol;Acc:HGNC:11955]",{"v":0.656349,"d":"0.66"},{"v":0.613845,"d":"0.61"},{"v":0.518428,"d":"0.52"},{"v":0.628148,"d":"0.63"},{"v":0.537176,"d":"0.54"},{"v":1.037501,"d":"1.04"},{"v":0.811967360094424,"d":"0.81"},{"v":-0.300506360551245,"d":"-0.30"},1,1,"down","no"]
[145433,0,"chr3","+",149976755,149979328,"ENST00000471176",3,680,"ENSG00000242791","AC117395","NA","NA","NA","NA","novel transcript",{"v":0.047512,"d":"0.05"},0,0,0,0,0,"inf","inf",1,1,"up","no"]
[174695,0,"chr6","-",145626790,145686877,"ENST00000640225",5,1516,"ENSG00000112425","EPM2A","GO:0000045(autophagosome assembly);GO:0001558(regulation of cell growth);GO:0001932(regulation of protein phosphorylation);GO:0004721(phosphoprotein phosphatase activity);GO:0004722(protein serine/threonine phosphatase activity);GO:0004725(protein tyrosine phosphatase activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005829(cytosol);GO:0005844(polysome);GO:0005886(plasma membrane);GO:0005975(carbohydrate metabolic process);GO:0005977(glycogen metabolic process);GO:0005978(glycogen biosynthetic process);GO:0006470(protein dephosphorylation);GO:0006816(calcium ion transport);GO:0006914(autophagy);GO:0007005(mitochondrion organization);GO:0007399(nervous system development);GO:0008138(protein tyrosine/serine/threonine phosphatase activity);GO:0010468(regulation of gene expression);GO:0010629(negative regulation of gene expression);GO:0014009(glial cell proliferation);GO:0015813(L-glutamate transmembrane transport);GO:0016020(membrane);GO:0016055(Wnt signaling pathway);GO:0016239(positive regulation of macroautophagy);GO:0016311(dephosphorylation);GO:0016787(hydrolase activity);GO:0016791(phosphatase activity);GO:0019203(carbohydrate phosphatase activity);GO:0030246(carbohydrate binding);GO:0030247(polysaccharide binding);GO:0030425(dendrite);GO:0031396(regulation of protein ubiquitination);GO:0033137(negative regulation of peptidyl-serine phosphorylation);GO:0035335(peptidyl-tyrosine dephosphorylation);GO:0042306(regulation of protein import into nucleus);GO:0042325(regulation of phosphorylation);GO:0042803(protein homodimerization activity);GO:0043161(proteasome-mediated ubiquitin-dependent protein catabolic process);GO:0043204(perikaryon);GO:0044260(cellular macromolecule metabolic process);GO:0045786(negative regulation of cell cycle);GO:0045859(regulation of protein kinase activity);GO:0046838(phosphorylated carbohydrate dephosphorylation);GO:0046959(habituation);GO:0051260(protein homooligomerization);GO:0061136(regulation of proteasomal protein catabolic process);GO:0098554(cytoplasmic side of endoplasmic reticulum membrane);GO:0098556(cytoplasmic side of rough endoplasmic reticulum membrane);GO:1903076(regulation of protein localization to plasma membrane);GO:1904666(regulation of ubiquitin protein ligase activity);GO:2000465(regulation of glycogen (starch) synthase activity);GO:2001069(glycogen binding);GO:2001070(starch binding)","NA","NA","NA","EPM2A, laforin glucan phosphatase [Source:HGNC Symbol;Acc:HGNC:3413]",0,0,0,0,0,0,1,0,1,1,"no","no"]
[54766,0,"chr14","-",23117304,23119616,"ENST00000206513",2,1554,"ENSG00000092067","CEBPE","GO:0000978(RNA polymerase II proximal promoter sequence-specific DNA binding);GO:0000981(DNA-binding transcription factor activity, RNA polymerase II-specific);GO:0001228(DNA-binding transcription activator activity, RNA polymerase II-specific);GO:0003677(DNA binding);GO:0003700(DNA-binding transcription factor activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0006355(regulation of transcription, DNA-templated);GO:0006909(phagocytosis);GO:0006952(defense response);GO:0010628(positive regulation of gene expression);GO:0030099(myeloid cell differentiation);GO:0030225(macrophage differentiation);GO:0030851(granulocyte differentiation);GO:0042089(cytokine biosynthetic process);GO:0042742(defense response to bacterium);GO:0042803(protein homodimerization activity);GO:0045944(positive regulation of transcription by RNA polymerase II);GO:0046982(protein heterodimerization activity);GO:0071222(cellular response to lipopolysaccharide)","05202(Transcriptional misregulation in cancer);05221(Acute myeloid leukemia)","NA","NA","CCAAT enhancer binding protein epsilon [Source:HGNC Symbol;Acc:HGNC:1836]",0,0,0,0,0,{"v":0.028534,"d":"0.03"},"-inf","-inf",1,1,"down","no"]
[4668,0,"chr1","-",39565299,39568408,"ENST00000513632",2,738,"ENSG00000090621","PABPC4","GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0003729(mRNA binding);GO:0003730(mRNA 3'-UTR binding);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0006396(RNA processing);GO:0006401(RNA catabolic process);GO:0006412(translation);GO:0007596(blood coagulation);GO:0008143(poly(A) binding);GO:0008266(poly(U) RNA binding);GO:0010494(cytoplasmic stress granule);GO:0043488(regulation of mRNA stability);GO:0061515(myeloid cell development);GO:1990904(ribonucleoprotein complex)","03013(RNA transport);03015(mRNA surveillance pathway);03018(RNA degradation)","K13126","NA","poly(A) binding protein cytoplasmic 4 [Source:HGNC Symbol;Acc:HGNC:8557]",{"v":0.307976,"d":"0.31"},{"v":0.11896,"d":"0.12"},{"v":0.505778,"d":"0.51"},{"v":0.635955,"d":"0.64"},{"v":0.351523,"d":"0.35"},{"v":0.492369,"d":"0.49"},{"v":0.630277319209351,"d":"0.63"},{"v":-0.665941347200359,"d":"-0.67"},1,1,"down","no"]
[202381,0,"chrX","+",40580894,40606588,"ENST00000636409",8,1962,"ENSG00000182220","ATP6AP2","GO:0002003(angiotensin maturation);GO:0003824(catalytic activity);GO:0005515(protein binding);GO:0005615(extracellular space);GO:0005886(plasma membrane);GO:0009897(external side of plasma membrane);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016324(apical plasma membrane);GO:0021903(rostrocaudal neural tube patterning);GO:0030177(positive regulation of Wnt signaling pathway);GO:0032914(positive regulation of transforming growth factor beta1 production);GO:0038023(signaling receptor activity);GO:0043005(neuron projection);GO:0043312(neutrophil degranulation);GO:0043408(regulation of MAPK cascade);GO:0044297(cell body);GO:0048069(eye pigmentation);GO:0060323(head morphogenesis);GO:0070062(extracellular exosome);GO:0070821(tertiary granule membrane);GO:0101003(ficolin-1-rich granule membrane)","04614(Renin-angiotensin system)","K19514","NA","ATPase H+ transporting accessory protein 2 [Source:HGNC Symbol;Acc:HGNC:18305]",{"v":0.001202,"d":"0.00"},{"v":0.001364,"d":"0.00"},{"v":0.075156,"d":"0.08"},{"v":0.166812,"d":"0.17"},{"v":0.295114,"d":"0.30"},{"v":0.797116,"d":"0.80"},{"v":0.0617310621885529,"d":"0.06"},{"v":-4.01785957416348,"d":"-4.02"},1,1,"down","no"]
[82590,0,"chr17","+",18928268,18931268,"ENST00000466106",2,1419,"ENSG00000141127","PRPSAP2","GO:0000287(magnesium ion binding);GO:0002189(ribose phosphate diphosphokinase complex);GO:0004749(ribose phosphate diphosphokinase activity);GO:0004857(enzyme inhibitor activity);GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0006015(5-phosphoribose 1-diphosphate biosynthetic process);GO:0006139(nucleobase-containing compound metabolic process);GO:0006164(purine nucleotide biosynthetic process);GO:0009116(nucleoside metabolic process);GO:0009165(nucleotide biosynthetic process);GO:0032991(protein-containing complex);GO:0043086(negative regulation of catalytic activity);GO:0060348(bone development)","NA","NA","NA","phosphoribosyl pyrophosphate synthetase associated protein 2 [Source:HGNC Symbol;Acc:HGNC:9467]",{"v":0.081718,"d":"0.08"},{"v":0.023928,"d":"0.02"},{"v":0.252258,"d":"0.25"},{"v":0.290487,"d":"0.29"},{"v":0.343953,"d":"0.34"},{"v":0.165497,"d":"0.17"},{"v":0.447415233949674,"d":"0.45"},{"v":-1.16031371562604,"d":"-1.16"},1,1,"down","no"]
[4578,0,"chr1","-",38874451,38876351,"ENST00000360786",1,1901,"ENSG00000131233","GJA9","GO:0005886(plasma membrane);GO:0005921(gap junction);GO:0005922(connexin complex);GO:0007154(cell communication);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0030054(cell junction)","NA","K07618","NA","gap junction protein alpha 9 [Source:HGNC Symbol;Acc:HGNC:19155]",{"v":0.027156,"d":"0.03"},{"v":0.0463,"d":"0.05"},{"v":0.04605,"d":"0.05"},{"v":0.022119,"d":"0.02"},{"v":0.016395,"d":"0.02"},{"v":0.05634,"d":"0.06"},{"v":1.25989415311953,"d":"1.26"},{"v":0.333302534372872,"d":"0.33"},1,1,"up","no"]
[151361,0,"chr4","-",53498773,53508383,"ENST00000511398",3,622,"ENSG00000072201","LNX1","GO:0004842(ubiquitin-protein transferase activity);GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0006511(ubiquitin-dependent protein catabolic process);GO:0016567(protein ubiquitination);GO:0016740(transferase activity);GO:0030165(PDZ domain binding);GO:0046872(metal ion binding);GO:0051260(protein homooligomerization)","NA","K10692","EC:2.3.2.27","ligand of numb-protein X 1 [Source:HGNC Symbol;Acc:HGNC:6657]",0,0,0,0,0,0,1,0,1,1,"no","no"]
[37379,0,"chr11","+",120477000,120477573,"ENST00000528681",2,433,"ENSG00000196914","ARHGEF12","GO:0001664(G protein-coupled receptor binding);GO:0005085(guanyl-nucleotide exchange factor activity);GO:0005089(Rho guanyl-nucleotide exchange factor activity);GO:0005096(GTPase activator activity);GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0007186(G protein-coupled receptor signaling pathway);GO:0007266(Rho protein signal transduction);GO:0016020(membrane);GO:0035023(regulation of Rho protein signal transduction);GO:0035556(intracellular signal transduction);GO:0043065(positive regulation of apoptotic process);GO:0043547(positive regulation of GTPase activity);GO:0051056(regulation of small GTPase mediated signal transduction);GO:0070062(extracellular exosome)","04270(Vascular smooth muscle contraction);04360(Axon guidance);04611(Platelet activation);04625(C-type lectin receptor signaling pathway);04810(Regulation of actin cytoskeleton);05152(Tuberculosis);05163(Human cytomegalovirus infection);05200(Pathways in cancer);05205(Proteoglycans in cancer)","K07532","NA","Rho guanine nucleotide exchange factor 12 [Source:HGNC Symbol;Acc:HGNC:14193]",{"v":0.051293,"d":"0.05"},{"v":0.048519,"d":"0.05"},{"v":0.11532,"d":"0.12"},{"v":0.0462,"d":"0.05"},{"v":0.054104,"d":"0.05"},{"v":0.227049,"d":"0.23"},{"v":0.657186584512743,"d":"0.66"},{"v":-0.605625064773571,"d":"-0.61"},1,1,"down","no"]
[32343,0,"chr11","+",65530767,65533258,"ENST00000529178",3,696,"ENSG00000142186","SCYL1","GO:0003677(DNA binding);GO:0004672(protein kinase activity);GO:0004713(protein tyrosine kinase activity);GO:0005524(ATP binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005793(endoplasmic reticulum-Golgi intermediate compartment);GO:0005794(Golgi apparatus);GO:0005801(cis-Golgi network);GO:0005815(microtubule organizing center);GO:0005829(cytosol);GO:0005856(cytoskeleton);GO:0006468(protein phosphorylation);GO:0006890(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum);GO:0016020(membrane);GO:0016192(vesicle-mediated transport);GO:0018108(peptidyl-tyrosine phosphorylation);GO:0030126(COPI vesicle coat);GO:0045296(cadherin binding)","NA","K08876","NA","SCY1 like pseudokinase 1 [Source:HGNC Symbol;Acc:HGNC:14372]",{"v":0.20251,"d":"0.20"},{"v":0.001268,"d":"0.00"},{"v":0.083587,"d":"0.08"},{"v":0.030856,"d":"0.03"},{"v":0.003195,"d":"0.00"},{"v":0.067023,"d":"0.07"},{"v":2.84311494548549,"d":"2.84"},{"v":1.50747242751688,"d":"1.51"},1,1,"up","no"]
[35040,0,"chr11","-",86556565,86672618,"ENST00000530335",4,814,"ENSG00000151376","ME3","GO:0004470(malic enzyme activity);GO:0004471(malate dehydrogenase (decarboxylating) (NAD+) activity);GO:0004473(malate dehydrogenase (decarboxylating) (NADP+) activity);GO:0005739(mitochondrion);GO:0005759(mitochondrial matrix);GO:0006090(pyruvate metabolic process);GO:0006099(tricarboxylic acid cycle);GO:0006108(malate metabolic process);GO:0008948(oxaloacetate decarboxylase activity);GO:0009060(aerobic respiration);GO:0016491(oxidoreductase activity);GO:0046872(metal ion binding);GO:0048037(cofactor binding);GO:0051287(NAD binding);GO:0055114(oxidation-reduction process);GO:0072592(oxygen metabolic process)","00620(Pyruvate metabolism)","K00029","EC:1.1.1.40","malic enzyme 3 [Source:HGNC Symbol;Acc:HGNC:6985]",{"v":0.660299,"d":"0.66"},{"v":0.408965,"d":"0.41"},{"v":0.384087,"d":"0.38"},{"v":0.295532,"d":"0.30"},{"v":0.740245,"d":"0.74"},{"v":0.170629,"d":"0.17"},{"v":1.20469477108038,"d":"1.20"},{"v":0.268667662613626,"d":"0.27"},1,1,"up","no"]
[71804,0,"chr16","-",15015828,15016390,"ENST00000617759",1,563,"ENSG00000275910","AC138932","NA","NA","NA","NA","novel transcript, antisense to PDXDC1",{"v":0.378025,"d":"0.38"},{"v":0.169501,"d":"0.17"},{"v":0.096928,"d":"0.10"},{"v":0.171885,"d":"0.17"},{"v":0.402228,"d":"0.40"},{"v":0.435135,"d":"0.44"},{"v":0.638548701607534,"d":"0.64"},{"v":-0.647131437546354,"d":"-0.65"},1,1,"down","no"]
[134832,0,"chr22","+",39421735,39428134,"ENST00000473491",3,574,"ENSG00000100324","TAB1","GO:0000185(activation of MAPKKK activity);GO:0000187(activation of MAPK activity);GO:0001701(in utero embryonic development);GO:0002223(stimulatory C-type lectin receptor signaling pathway);GO:0002755(MyD88-dependent toll-like receptor signaling pathway);GO:0003007(heart morphogenesis);GO:0003279(cardiac septum development);GO:0003824(catalytic activity);GO:0004722(protein serine/threonine phosphatase activity);GO:0004724(magnesium-dependent protein serine/threonine phosphatase activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005829(cytosol);GO:0006470(protein dephosphorylation);GO:0007179(transforming growth factor beta receptor signaling pathway);GO:0007249(I-kappaB kinase/NF-kappaB signaling);GO:0007254(JNK cascade);GO:0008047(enzyme activator activity);GO:0010008(endosome membrane);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0016579(protein deubiquitination);GO:0016607(nuclear speck);GO:0019209(kinase activator activity);GO:0030295(protein kinase activator activity);GO:0030324(lung development);GO:0032991(protein-containing complex);GO:0035904(aorta development);GO:0038095(Fc-epsilon receptor signaling pathway);GO:0043406(positive regulation of MAP kinase activity);GO:0044877(protein-containing complex binding);GO:0048273(mitogen-activated protein kinase p38 binding);GO:0051092(positive regulation of NF-kappaB transcription factor activity);GO:0060976(coronary vasculature development);GO:0070423(nucleotide-binding oligomerization domain containing signaling pathway);GO:0070498(interleukin-1-mediated signaling pathway)","04010(MAPK signaling pathway);04064(NF-kappa B signaling pathway);04380(Osteoclast differentiation);04620(Toll-like receptor signaling pathway);04621(NOD-like receptor signaling pathway);04668(TNF signaling pathway);05140(Leishmaniasis);05145(Toxoplasmosis);05161(Hepatitis B);05168(Herpes simplex virus 1 infection);05169(Epstein-Barr virus infection);05170(Human immunodeficiency virus 1 infection)","K04403","NA","TGF-beta activated kinase 1 (MAP3K7) binding protein 1 [Source:HGNC Symbol;Acc:HGNC:18157]",{"v":0.011882,"d":"0.01"},{"v":0.12406,"d":"0.12"},{"v":0.158553,"d":"0.16"},{"v":0.007154,"d":"0.01"},{"v":0.019628,"d":"0.02"},{"v":0.003604,"d":"0.00"},{"v":9.69179885473573,"d":"9.69"},{"v":3.27676446315837,"d":"3.28"},1,1,"up","no"]
[47486,0,"chr12","+",106774682,106814966,"ENST00000552619",2,419,"ENSG00000111785","RIC8B","GO:0001965(G-protein alpha-subunit binding);GO:0005085(guanyl-nucleotide exchange factor activity);GO:0005096(GTPase activator activity);GO:0005737(cytoplasm);GO:0005813(centrosome);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0005938(cell cortex);GO:0007186(G protein-coupled receptor signaling pathway);GO:0008277(regulation of G protein-coupled receptor signaling pathway);GO:0043547(positive regulation of GTPase activity)","NA","NA","NA","RIC8 guanine nucleotide exchange factor B [Source:HGNC Symbol;Acc:HGNC:25555]",0,0,0,0,0,{"v":0.034471,"d":"0.03"},"-inf","-inf",1,1,"down","no"]
[2433,0,"chr1","-",20725932,20731591,"ENST00000517430",5,564,"ENSG00000189410","SH2D5","GO:0005515(protein binding);GO:0005886(plasma membrane);GO:0014069(postsynaptic density);GO:0016020(membrane);GO:0030054(cell junction);GO:0045202(synapse);GO:0045211(postsynaptic membrane)","NA","NA","NA","SH2 domain containing 5 [Source:HGNC Symbol;Acc:HGNC:28819]",0,0,0,0,{"v":0.186927,"d":"0.19"},0,"-inf","-inf",1,1,"down","no"]
[203803,0,"chrX","-",63639415,63755127,"ENST00000636926",11,5436,"ENSG00000131089","ARHGEF9","GO:0005085(guanyl-nucleotide exchange factor activity);GO:0005089(Rho guanyl-nucleotide exchange factor activity);GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0007186(G protein-coupled receptor signaling pathway);GO:0014069(postsynaptic density);GO:0016020(membrane);GO:0030054(cell junction);GO:0035023(regulation of Rho protein signal transduction);GO:0043065(positive regulation of apoptotic process);GO:0045202(synapse);GO:0045211(postsynaptic membrane);GO:0051056(regulation of small GTPase mediated signal transduction);GO:0098982(GABA-ergic synapse);GO:0099150(regulation of postsynaptic specialization assembly)","NA","K20686","NA","Cdc42 guanine nucleotide exchange factor 9 [Source:HGNC Symbol;Acc:HGNC:14561]",{"v":0.13444,"d":"0.13"},{"v":0.097148,"d":"0.10"},{"v":0.150759,"d":"0.15"},{"v":0.039766,"d":"0.04"},{"v":0.095364,"d":"0.10"},{"v":0.043039,"d":"0.04"},{"v":2.1459793791288,"d":"2.15"},{"v":1.10163621319996,"d":"1.10"},1,1,"up","no"]
[37835,0,"chr11","+",125569840,125577570,"ENST00000527520",5,452,"ENSG00000149547","EI24","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005794(Golgi apparatus);GO:0005829(cytosol);GO:0006914(autophagy);GO:0006915(apoptotic process);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016236(macroautophagy);GO:0030308(negative regulation of cell growth);GO:0031965(nuclear membrane)","04115(p53 signaling pathway)","K10134","NA","EI24, autophagy associated transmembrane protein [Source:HGNC Symbol;Acc:HGNC:13276]",{"v":0.050679,"d":"0.05"},0,{"v":0.04146,"d":"0.04"},0,{"v":0.109408,"d":"0.11"},{"v":0.089581,"d":"0.09"},{"v":0.463035645186417,"d":"0.46"},{"v":-1.11080483627392,"d":"-1.11"},1,1,"down","no"]
[72999,0,"chr16","-",27470223,27478594,"ENST00000569394",4,566,"ENSG00000077235","GTF3C1","GO:0000127(transcription factor TFIIIC complex);GO:0000995(RNA polymerase III general transcription initiation factor activity);GO:0001002(RNA polymerase III type 1 promoter sequence-specific DNA binding);GO:0001003(RNA polymerase III type 2 promoter sequence-specific DNA binding);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005730(nucleolus);GO:0006383(transcription by RNA polymerase III);GO:0006384(transcription initiation from RNA polymerase III promoter);GO:0009303(rRNA transcription);GO:0009304(tRNA transcription);GO:0016020(membrane);GO:0042791(5S class rRNA transcription by RNA polymerase III);GO:0042797(tRNA transcription by RNA polymerase III);GO:1990904(ribonucleoprotein complex)","NA","K15199","NA","general transcription factor IIIC subunit 1 [Source:HGNC Symbol;Acc:HGNC:4664]",{"v":0.339246,"d":"0.34"},{"v":0.315686,"d":"0.32"},{"v":0.16761,"d":"0.17"},{"v":0.299299,"d":"0.30"},{"v":0.605291,"d":"0.61"},{"v":0.203525,"d":"0.20"},{"v":0.742289383322128,"d":"0.74"},{"v":-0.429946360206972,"d":"-0.43"},1,1,"down","no"]
[36330,0,"chr11","-",112267290,112268371,"ENST00000526466",1,1082,"ENSG00000213234","ST13P10","NA","NA","NA","NA","ST13, Hsp70 interacting protein pseudogene 10 [Source:HGNC Symbol;Acc:HGNC:38745]",0,0,0,0,0,0,1,0,1,1,"no","no"]
[29707,0,"chr11","+",46702715,46704522,"ENST00000527008",2,699,"ENSG00000175213","ZNF408","GO:0000981(DNA-binding transcription factor activity, RNA polymerase II-specific);GO:0003676(nucleic acid binding);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0005634(nucleus);GO:0006357(regulation of transcription by RNA polymerase II);GO:0042802(identical protein binding);GO:0046872(metal ion binding)","NA","NA","NA","zinc finger protein 408 [Source:HGNC Symbol;Acc:HGNC:20041]",{"v":0.038942,"d":"0.04"},{"v":0.104019,"d":"0.10"},{"v":0.05577,"d":"0.06"},{"v":0.046097,"d":"0.05"},{"v":0.100649,"d":"0.10"},{"v":0.10348,"d":"0.10"},{"v":0.794206037741881,"d":"0.79"},{"v":-0.332414766274843,"d":"-0.33"},1,1,"down","no"]
[165519,0,"chr5","+",173057394,173086569,"ENST00000523161",3,559,"ENSG00000164463","CREBRF","GO:0000977(RNA polymerase II regulatory region sequence-specific DNA binding);GO:0000981(DNA-binding transcription factor activity, RNA polymerase II-specific);GO:0001228(DNA-binding transcription activator activity, RNA polymerase II-specific);GO:0003700(DNA-binding transcription factor activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0006355(regulation of transcription, DNA-templated);GO:0006986(response to unfolded protein);GO:0016604(nuclear body);GO:0030968(endoplasmic reticulum unfolded protein response);GO:0042711(maternal behavior);GO:0045944(positive regulation of transcription by RNA polymerase II);GO:1900170(negative regulation of glucocorticoid mediated signaling pathway);GO:1902213(positive regulation of prolactin signaling pathway)","NA","K21554","NA","CREB3 regulatory factor [Source:HGNC Symbol;Acc:HGNC:24050]",{"v":0.458545,"d":"0.46"},0,{"v":0.577178,"d":"0.58"},{"v":0.130994,"d":"0.13"},{"v":0.531486,"d":"0.53"},0,{"v":1.56340266875981,"d":"1.56"},{"v":0.644689405595907,"d":"0.64"},1,1,"up","no"]
[67194,0,"chr15","+",78876492,78894134,"ENST00000560422",10,761,"ENSG00000185787","MORF4L1","GO:0000123(histone acetyltransferase complex);GO:0000724(double-strand break repair via homologous recombination);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0006281(DNA repair);GO:0006310(DNA recombination);GO:0006325(chromatin organization);GO:0006342(chromatin silencing);GO:0006355(regulation of transcription, DNA-templated);GO:0006974(cellular response to DNA damage stimulus);GO:0016573(histone acetylation);GO:0016575(histone deacetylation);GO:0016580(Sin3 complex);GO:0016607(nuclear speck);GO:0035267(NuA4 histone acetyltransferase complex);GO:0040008(regulation of growth);GO:0043967(histone H4 acetylation);GO:0043968(histone H2A acetylation);GO:0047485(protein N-terminus binding)","NA","K11339","NA","mortality factor 4 like 1 [Source:HGNC Symbol;Acc:HGNC:16989]",{"v":0.017414,"d":"0.02"},{"v":0.018747,"d":"0.02"},{"v":0.045175,"d":"0.05"},0,0,0,"inf","inf",1,1,"up","no"]
[96450,0,"chr19","+",1040118,1042465,"ENST00000525238",4,1100,"ENSG00000064687","ABCA7","GO:0000139(Golgi membrane);GO:0000166(nucleotide binding);GO:0001891(phagocytic cup);GO:0005215(transporter activity);GO:0005319(lipid transporter activity);GO:0005515(protein binding);GO:0005524(ATP binding);GO:0005737(cytoplasm);GO:0005768(endosome);GO:0005783(endoplasmic reticulum);GO:0005794(Golgi apparatus);GO:0005886(plasma membrane);GO:0006869(lipid transport);GO:0006909(phagocytosis);GO:0007613(memory);GO:0009986(cell surface);GO:0010875(positive regulation of cholesterol efflux);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016887(ATPase activity);GO:0018149(peptide cross-linking);GO:0030054(cell junction);GO:0031901(early endosome membrane);GO:0032587(ruffle membrane);GO:0033344(cholesterol efflux);GO:0033700(phospholipid efflux);GO:0034188(apolipoprotein A-I receptor activity);GO:0034205(amyloid-beta formation);GO:0034380(high-density lipoprotein particle assembly);GO:0034504(protein localization to nucleus);GO:0038027(apolipoprotein A-I-mediated signaling pathway);GO:0042626(ATPase activity, coupled to transmembrane movement of substances);GO:0042985(negative regulation of amyloid precursor protein biosynthetic process);GO:0042995(cell projection);GO:0043190(ATP-binding cassette (ABC) transporter complex);GO:0043231(intracellular membrane-bounded organelle);GO:0044857(plasma membrane raft organization);GO:0045332(phospholipid translocation);GO:0045806(negative regulation of endocytosis);GO:0050766(positive regulation of phagocytosis);GO:0055085(transmembrane transport);GO:0070374(positive regulation of ERK1 and ERK2 cascade);GO:0090554(phosphatidylcholine-translocating ATPase activity);GO:0090556(phosphatidylserine-translocating ATPase activity);GO:0097386(glial cell projection);GO:0150094(amyloid-beta clearance by cellular catabolic process);GO:1900223(positive regulation of amyloid-beta clearance);GO:1901076(positive regulation of engulfment of apoptotic cell);GO:1902430(negative regulation of amyloid-beta formation);GO:1902991(regulation of amyloid precursor protein catabolic process);GO:1902995(positive regulation of phospholipid efflux);GO:2000010(positive regulation of protein localization to cell surface)","02010(ABC transporters)","K05645","NA","ATP binding cassette subfamily A member 7 [Source:HGNC Symbol;Acc:HGNC:37]",{"v":0.046431,"d":"0.05"},{"v":0.053201,"d":"0.05"},0,0,0,{"v":0.05905,"d":"0.06"},{"v":1.68724809483489,"d":"1.69"},{"v":0.75467212470539,"d":"0.75"},1,1,"up","no"]
[88830,0,"chr17","+",63486823,63493657,"ENST00000584865",6,1080,"ENSG00000159640","ACE","GO:0001822(kidney development);GO:0001974(blood vessel remodeling);GO:0002003(angiotensin maturation);GO:0002019(regulation of renal output by angiotensin);GO:0002446(neutrophil mediated immunity);GO:0002474(antigen processing and presentation of peptide antigen via MHC class I);GO:0003081(regulation of systemic arterial blood pressure by renin-angiotensin);GO:0003084(positive regulation of systemic arterial blood pressure);GO:0004175(endopeptidase activity);GO:0004180(carboxypeptidase activity);GO:0005576(extracellular region);GO:0005615(extracellular space);GO:0005737(cytoplasm);GO:0005764(lysosome);GO:0005768(endosome);GO:0005886(plasma membrane);GO:0006508(proteolysis);GO:0007283(spermatogenesis);GO:0008144(drug binding);GO:0008217(regulation of blood pressure);GO:0008233(peptidase activity);GO:0008237(metallopeptidase activity);GO:0008238(exopeptidase activity);GO:0008239(dipeptidyl-peptidase activity);GO:0008240(tripeptidyl-peptidase activity);GO:0008241(peptidyl-dipeptidase activity);GO:0008270(zinc ion binding);GO:0009897(external side of plasma membrane);GO:0010608(posttranscriptional regulation of gene expression);GO:0010629(negative regulation of gene expression);GO:0014910(regulation of smooth muscle cell migration);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016787(hydrolase activity);GO:0019229(regulation of vasoconstriction);GO:0031404(chloride ion binding);GO:0031434(mitogen-activated protein kinase kinase binding);GO:0031711(bradykinin receptor binding);GO:0032091(negative regulation of protein binding);GO:0032092(positive regulation of protein binding);GO:0032943(mononuclear cell proliferation);GO:0042447(hormone catabolic process);GO:0043171(peptide catabolic process);GO:0045777(positive regulation of blood pressure);GO:0046872(metal ion binding);GO:0050435(amyloid-beta metabolic process);GO:0050482(arachidonic acid secretion);GO:0051019(mitogen-activated protein kinase binding);GO:0060047(heart contraction);GO:0060177(regulation of angiotensin metabolic process);GO:0060218(hematopoietic stem cell differentiation);GO:0061098(positive regulation of protein tyrosine kinase activity);GO:0070062(extracellular exosome);GO:0070573(metallodipeptidase activity);GO:0071838(cell proliferation in bone marrow);GO:0097746(regulation of blood vessel diameter);GO:1900086(positive regulation of peptidyl-tyrosine autophosphorylation);GO:1902033(regulation of hematopoietic stem cell proliferation);GO:1903597(negative regulation of gap junction assembly);GO:2000170(positive regulation of peptidyl-cysteine S-nitrosylation)","04614(Renin-angiotensin system);04924(Renin secretion);05142(Chagas disease (American trypanosomiasis));05410(Hypertrophic cardiomyopathy (HCM))","NA","NA","angiotensin I converting enzyme [Source:HGNC Symbol;Acc:HGNC:2707]",{"v":0.322618,"d":"0.32"},{"v":0.165924,"d":"0.17"},{"v":0.133705,"d":"0.13"},{"v":0.025051,"d":"0.03"},{"v":0.161055,"d":"0.16"},{"v":0.225943,"d":"0.23"},{"v":1.51012864974797,"d":"1.51"},{"v":0.594671459780374,"d":"0.59"},1,1,"up","no"]
[137104,0,"chr3","+",13926813,13927778,"ENST00000425215",1,966,"ENSG00000233121","VN1R20P","NA","NA","NA","NA","vomeronasal 1 receptor 20 pseudogene [Source:HGNC Symbol;Acc:HGNC:37335]",{"v":0.091253,"d":"0.09"},{"v":0.045557,"d":"0.05"},{"v":0.036639,"d":"0.04"},{"v":0.043528,"d":"0.04"},0,{"v":0.040694,"d":"0.04"},{"v":2.0594262781696,"d":"2.06"},{"v":1.0422424825923,"d":"1.04"},1,1,"up","no"]
[12871,0,"chr1","-",159854316,159862657,"ENST00000368100",7,1818,"ENSG00000243284","VSIG8","GO:0003723(RNA binding);GO:0016020(membrane);GO:0016021(integral component of membrane)","NA","NA","NA","V-set and immunoglobulin domain containing 8 [Source:HGNC Symbol;Acc:HGNC:32063]",0,0,{"v":0.02233,"d":"0.02"},0,0,0,"inf","inf",1,1,"up","no"]
[66248,0,"chr15","-",73916304,73926298,"ENST00000567644",4,640,"ENSG00000261801","LOXL1-AS1","NA","NA","NA","NA","LOXL1 antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:44169]",{"v":0.499035,"d":"0.50"},{"v":0.122708,"d":"0.12"},{"v":0.055626,"d":"0.06"},{"v":0.200748,"d":"0.20"},{"v":0.330987,"d":"0.33"},{"v":0.544894,"d":"0.54"},{"v":0.629157304884041,"d":"0.63"},{"v":-0.668507323246915,"d":"-0.67"},1,1,"down","no"]
[49219,0,"chr12","-",122519910,122526954,"ENST00000525387",4,980,"ENSG00000111011","RSRC2","GO:0003723(RNA binding)","NA","NA","NA","arginine and serine rich coiled-coil 2 [Source:HGNC Symbol;Acc:HGNC:30559]",{"v":0.321169,"d":"0.32"},{"v":0.397779,"d":"0.40"},{"v":0.16152,"d":"0.16"},{"v":0.415392,"d":"0.42"},{"v":0.417117,"d":"0.42"},{"v":0.288255,"d":"0.29"},{"v":0.78559625398389,"d":"0.79"},{"v":-0.3481400445267,"d":"-0.35"},1,1,"down","no"]
[167046,0,"chr6","-",5664985,5695272,"ENST00000602500",4,806,"ENSG00000270174","AL022097","NA","NA","NA","NA","novel transcript, antisense to FARS2",0,0,0,0,0,0,1,0,1,1,"no","no"]
[106419,0,"chr19","+",49542602,49543633,"ENST00000593483",2,595,"ENSG00000142552","RCN3","GO:0005509(calcium ion binding);GO:0005515(protein binding);GO:0005783(endoplasmic reticulum);GO:0005788(endoplasmic reticulum lumen);GO:0009306(protein secretion);GO:0010952(positive regulation of peptidase activity);GO:0015031(protein transport);GO:0032964(collagen biosynthetic process);GO:0036503(ERAD pathway);GO:0043129(surfactant homeostasis);GO:0046872(metal ion binding);GO:0051896(regulation of protein kinase B signaling);GO:0055091(phospholipid homeostasis);GO:0060428(lung epithelium development)","NA","NA","NA","reticulocalbin 3 [Source:HGNC Symbol;Acc:HGNC:21145]",0,0,0,0,0,0,1,0,1,1,"no","no"]
[45904,0,"chr12","-",75563202,75984015,"ENST00000552856",5,748,"ENSG00000258077","AC078923","NA","NA","NA","NA","novel transcript",0,{"v":0.058626,"d":"0.06"},0,0,0,0,"inf","inf",1,1,"up","no"]
[39774,0,"chr12","-",8396423,8396641,"ENST00000642101",1,219,"ENSG00000284673","AC092865","NA","NA","NA","NA","RNA binding protein, fox-1 homolog (C. elegans) 1 (RBFOX1) pseudogene",0,0,{"v":0.188665,"d":"0.19"},{"v":0.085788,"d":"0.09"},0,0,{"v":2.19920035436192,"d":"2.20"},{"v":1.1369790444281,"d":"1.14"},1,1,"up","no"]
[104967,0,"chr19","-",44329720,44356674,"ENST00000592151",5,534,"ENSG00000062370","ZNF112","GO:0003676(nucleic acid binding);GO:0003677(DNA binding);GO:0005622(intracellular);GO:0005634(nucleus);GO:0006355(regulation of transcription, DNA-templated);GO:0046872(metal ion binding)","05168(Herpes simplex virus 1 infection)","K09228","NA","zinc finger protein 112 [Source:HGNC Symbol;Acc:HGNC:12892]",0,0,0,0,{"v":0.180029,"d":"0.18"},0,"-inf","-inf",1,1,"down","no"]
[37584,0,"chr11","-",123730808,123741675,"ENST00000529250",4,541,"ENSG00000166261","ZNF202","GO:0000122(negative regulation of transcription by RNA polymerase II);GO:0000978(RNA polymerase II proximal promoter sequence-specific DNA binding);GO:0000981(DNA-binding transcription factor activity, RNA polymerase II-specific);GO:0001227(DNA-binding transcription repressor activity, RNA polymerase II-specific);GO:0003676(nucleic acid binding);GO:0003677(DNA binding);GO:0003700(DNA-binding transcription factor activity);GO:0005515(protein binding);GO:0005622(intracellular);GO:0005634(nucleus);GO:0006355(regulation of transcription, DNA-templated);GO:0006366(transcription by RNA polymerase II);GO:0006629(lipid metabolic process);GO:0046872(metal ion binding)","NA","K09229","NA","zinc finger protein 202 [Source:HGNC Symbol;Acc:HGNC:12994]",{"v":0.494204,"d":"0.49"},{"v":0.847407,"d":"0.85"},{"v":0.34465,"d":"0.34"},{"v":0.504802,"d":"0.50"},{"v":0.673445,"d":"0.67"},{"v":0.278262,"d":"0.28"},{"v":1.15774155875453,"d":"1.16"},{"v":0.21131323820129,"d":"0.21"},1,1,"up","no"]
[60337,0,"chr14","+",100948978,100958550,"ENST00000414488",8,800,"ENSG00000225746","MEG8","NA","NA","NA","NA","maternally expressed 8, small nucleolar RNA host gene [Source:HGNC Symbol;Acc:HGNC:14574]",0,0,{"v":0.060682,"d":"0.06"},0,0,0,"inf","inf",1,1,"up","no"]
[157597,0,"chr5","+",10353968,10390491,"ENST00000510872",6,577,"ENSG00000145495","MARCH6","GO:0000835(ER ubiquitin ligase complex);GO:0004842(ubiquitin-protein transferase activity);GO:0005515(protein binding);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0008270(zinc ion binding);GO:0010498(proteasomal protein catabolic process);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016567(protein ubiquitination);GO:0016740(transferase activity);GO:0019899(enzyme binding);GO:0030176(integral component of endoplasmic reticulum membrane);GO:0030433(ubiquitin-dependent ERAD pathway);GO:0031624(ubiquitin conjugating enzyme binding);GO:0036503(ERAD pathway);GO:0044322(endoplasmic reticulum quality control compartment);GO:0046872(metal ion binding);GO:0061630(ubiquitin protein ligase activity);GO:0070936(protein K48-linked ubiquitination);GO:1904380(endoplasmic reticulum mannose trimming);GO:1990381(ubiquitin-specific protease binding)","04141(Protein processing in endoplasmic reticulum)","K10661","EC:2.3.2.27","membrane associated ring-CH-type finger 6 [Source:HGNC Symbol;Acc:HGNC:30550]",0,{"v":0.023103,"d":"0.02"},0,0,0,0,"inf","inf",1,1,"up","no"]
[122515,0,"chr2","+",219613916,219615995,"ENST00000447191",5,705,"ENSG00000144589","STK11IP","GO:0005515(protein binding);GO:0005576(extracellular region);GO:0005737(cytoplasm);GO:0005765(lysosomal membrane);GO:0008104(protein localization);GO:0019901(protein kinase binding);GO:0035578(azurophil granule lumen);GO:0043231(intracellular membrane-bounded organelle);GO:0043312(neutrophil degranulation)","NA","NA","NA","serine/threonine kinase 11 interacting protein [Source:HGNC Symbol;Acc:HGNC:19184]",{"v":0.025556,"d":"0.03"},{"v":0.068175,"d":"0.07"},{"v":0.090596,"d":"0.09"},{"v":0.059643,"d":"0.06"},{"v":0.17509,"d":"0.18"},{"v":0.020296,"d":"0.02"},{"v":0.722768783157994,"d":"0.72"},{"v":-0.468393898252802,"d":"-0.47"},1,1,"down","no"]
[119784,0,"chr2","+",178528765,178632436,"ENST00000628296",5,483,"ENSG00000237298","TTN-AS1","NA","NA","NA","NA","TTN antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:44124]",{"v":0.014852,"d":"0.01"},0,{"v":0.010784,"d":"0.01"},0,0,{"v":0.383794,"d":"0.38"},{"v":0.066796250071653,"d":"0.07"},{"v":-3.90408907741799,"d":"-3.90"},1,1,"down","no"]
[22103,0,"chr10","-",73814300,73848018,"ENST00000441192",13,1224,"ENSG00000148660","CAMK2G","GO:0000082(G1/S transition of mitotic cell cycle);GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0004683(calmodulin-dependent protein kinase activity);GO:0004723(calcium-dependent protein serine/threonine phosphatase activity);GO:0005515(protein binding);GO:0005516(calmodulin binding);GO:0005524(ATP binding);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0006468(protein phosphorylation);GO:0006470(protein dephosphorylation);GO:0006816(calcium ion transport);GO:0007275(multicellular organism development);GO:0007399(nervous system development);GO:0014069(postsynaptic density);GO:0014733(regulation of skeletal muscle adaptation);GO:0016020(membrane);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0016529(sarcoplasmic reticulum);GO:0016740(transferase activity);GO:0030073(insulin secretion);GO:0030154(cell differentiation);GO:0030666(endocytic vesicle membrane);GO:0033017(sarcoplasmic reticulum membrane);GO:0042802(identical protein binding);GO:0042803(protein homodimerization activity);GO:0043005(neuron projection);GO:0046777(protein autophosphorylation);GO:0051259(protein complex oligomerization);GO:0051924(regulation of calcium ion transport);GO:0060333(interferon-gamma-mediated signaling pathway);GO:1900034(regulation of cellular response to heat);GO:1901897(regulation of relaxation of cardiac muscle)","04012(ErbB signaling pathway);04020(Calcium signaling pathway);04024(cAMP signaling pathway);04066(HIF-1 signaling pathway);04114(Oocyte meiosis);04217(Necroptosis);04261(Adrenergic signaling in cardiomyocytes);04310(Wnt signaling pathway);04360(Axon guidance);04713(Circadian entrainment);04720(Long-term potentiation);04722(Neurotrophin signaling pathway);04725(Cholinergic synapse);04728(Dopaminergic synapse);04740(Olfactory transduction);04750(Inflammatory mediator regulation of TRP channels);04911(Insulin secretion);04912(GnRH signaling pathway);04916(Melanogenesis);04921(Oxytocin signaling pathway);04922(Glucagon signaling pathway);04925(Aldosterone synthesis and secretion);04934(Cushing syndrome);04971(Gastric acid secretion);05031(Amphetamine addiction);05152(Tuberculosis);05200(Pathways in cancer);05205(Proteoglycans in cancer);05214(Glioma)","NA","NA","calcium/calmodulin dependent protein kinase II gamma [Source:HGNC Symbol;Acc:HGNC:1463]",{"v":0.001662,"d":"0.00"},{"v":0.000534,"d":"0.00"},{"v":0.006918,"d":"0.01"},{"v":9.9e-5,"d":"0.00"},{"v":0.004391,"d":"0.00"},{"v":6.5e-5,"d":"0.00"},{"v":2.00087815587267,"d":"2.00"},{"v":1.00063331653383,"d":"1.00"},1,1,"up","no"]
[98682,0,"chr19","+",10251944,10258667,"ENST00000591054",8,777,"ENSG00000105364","MRPL4","GO:0003723(RNA binding);GO:0003735(structural constituent of ribosome);GO:0005515(protein binding);GO:0005739(mitochondrion);GO:0005743(mitochondrial inner membrane);GO:0005762(mitochondrial large ribosomal subunit);GO:0005840(ribosome);GO:0006412(translation);GO:0070125(mitochondrial translational elongation);GO:0070126(mitochondrial translational termination)","03010(Ribosome)","K02926","NA","mitochondrial ribosomal protein L4 [Source:HGNC Symbol;Acc:HGNC:14276]",0,{"v":0.411025,"d":"0.41"},0,0,0,0,"inf","inf",1,1,"up","no"]
[15900,0,"chr1","+",206472854,206476260,"ENST00000605726",5,580,"ENSG00000263528","IKBKE","GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0004704(NF-kappaB-inducing kinase activity);GO:0005515(protein binding);GO:0005524(ATP binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0006468(protein phosphorylation);GO:0006955(immune response);GO:0006974(cellular response to DNA damage stimulus);GO:0007252(I-kappaB phosphorylation);GO:0008384(IkappaB kinase activity);GO:0008630(intrinsic apoptotic signaling pathway in response to DNA damage);GO:0010008(endosome membrane);GO:0010884(positive regulation of lipid storage);GO:0016032(viral process);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0016605(PML body);GO:0016740(transferase activity);GO:0018105(peptidyl-serine phosphorylation);GO:0019903(protein phosphatase binding);GO:0031625(ubiquitin protein ligase binding);GO:0031966(mitochondrial membrane);GO:0032480(negative regulation of type I interferon production);GO:0034340(response to type I interferon);GO:0035456(response to interferon-beta);GO:0035666(TRIF-dependent toll-like receptor signaling pathway);GO:0036435(K48-linked polyubiquitin modification-dependent protein binding);GO:0038061(NIK/NF-kappaB signaling);GO:0043123(positive regulation of I-kappaB kinase/NF-kappaB signaling);GO:0051260(protein homooligomerization);GO:0060340(positive regulation of type I interferon-mediated signaling pathway);GO:0098586(cellular response to virus)","04620(Toll-like receptor signaling pathway);04621(NOD-like receptor signaling pathway);04622(RIG-I-like receptor signaling pathway);04623(Cytosolic DNA-sensing pathway);04625(C-type lectin receptor signaling pathway);04657(IL-17 signaling pathway);05160(Hepatitis C);05161(Hepatitis B);05162(Measles);05164(Influenza A);05165(Human papillomavirus infection);05167(Kaposi sarcoma-associated herpesvirus infection);05168(Herpes simplex virus 1 infection);05169(Epstein-Barr virus infection)","K07211","EC:2.7.11.10","inhibitor of nuclear factor kappa B kinase subunit epsilon [Source:HGNC Symbol;Acc:HGNC:14552]",0,0,0,0,0,0,1,0,1,1,"no","no"]
[144684,0,"chr3","-",138086974,138088900,"ENST00000473850",2,572,"ENSG00000158163","DZIP1L","GO:0003676(nucleic acid binding);GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0005814(centriole);GO:0005856(cytoskeleton);GO:0005929(cilium);GO:0032880(regulation of protein localization);GO:0036064(ciliary basal body);GO:0042995(cell projection);GO:0046872(metal ion binding);GO:0060271(cilium assembly)","NA","K16470","NA","DAZ interacting zinc finger protein 1 like [Source:HGNC Symbol;Acc:HGNC:26551]",{"v":0.419541,"d":"0.42"},{"v":0.229494,"d":"0.23"},{"v":0.232617,"d":"0.23"},{"v":0.325729,"d":"0.33"},{"v":0.338516,"d":"0.34"},{"v":0.281476,"d":"0.28"},{"v":0.932253804240363,"d":"0.93"},{"v":-0.101205315682753,"d":"-0.10"},1,1,"down","no"]
[65395,0,"chr15","-",65093006,65106359,"ENST00000502113",5,1381,"ENSG00000246922","UBAP1L","GO:0000813(ESCRT I complex);GO:0043130(ubiquitin binding);GO:0043162(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)","NA","NA","NA","ubiquitin associated protein 1 like [Source:HGNC Symbol;Acc:HGNC:40028]",0,0,0,{"v":0.00338,"d":"0.00"},0,0,"-inf","-inf",1,1,"down","no"]
[206041,0,"chrX","+",130339910,130365563,"ENST00000464342",8,734,"ENSG00000102078","SLC25A14","GO:0005739(mitochondrion);GO:0005740(mitochondrial envelope);GO:0005743(mitochondrial inner membrane);GO:0005887(integral component of plasma membrane);GO:0006839(mitochondrial transport);GO:0008272(sulfate transport);GO:0009060(aerobic respiration);GO:0015116(sulfate transmembrane transporter activity);GO:0015117(thiosulfate transmembrane transporter activity);GO:0015131(oxaloacetate transmembrane transporter activity);GO:0015140(malate transmembrane transporter activity);GO:0015141(succinate transmembrane transporter activity);GO:0015297(antiporter activity);GO:0015709(thiosulfate transport);GO:0015729(oxaloacetate transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0022857(transmembrane transporter activity);GO:0031966(mitochondrial membrane);GO:0035435(phosphate ion transmembrane transport);GO:0055085(transmembrane transport);GO:0071422(succinate transmembrane transport);GO:0071423(malate transmembrane transport);GO:1902356(oxaloacetate(2-) transmembrane transport);GO:1902358(sulfate transmembrane transport);GO:1902600(proton transmembrane transport)","NA","NA","NA","solute carrier family 25 member 14 [Source:HGNC Symbol;Acc:HGNC:10984]",{"v":0.049395,"d":"0.05"},{"v":0.082828,"d":"0.08"},{"v":0.621181,"d":"0.62"},{"v":0.142666,"d":"0.14"},{"v":0.037711,"d":"0.04"},{"v":0.371432,"d":"0.37"},{"v":1.36533474444962,"d":"1.37"},{"v":0.449254705688106,"d":"0.45"},1,1,"up","no"]
[114704,0,"chr2","-",86143949,86195464,"ENST00000620815",8,1520,"ENSG00000132305","IMMT","GO:0003723(RNA binding);GO:0005515(protein binding);GO:0005739(mitochondrion);GO:0005743(mitochondrial inner membrane);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0042407(cristae formation);GO:0051560(mitochondrial calcium ion homeostasis);GO:0061617(MICOS complex)","NA","K17785","NA","inner membrane mitochondrial protein [Source:HGNC Symbol;Acc:HGNC:6047]",0,{"v":0.025648,"d":"0.03"},{"v":0.723359,"d":"0.72"},0,0,{"v":0.024786,"d":"0.02"},{"v":30.218954248366,"d":"30.22"},{"v":4.91738183061178,"d":"4.92"},1,1,"up","no"]
[119960,0,"chr2","+",182030883,182117511,"ENST00000479855",4,501,"ENSG00000150722","PPP1R1C","GO:0004864(protein phosphatase inhibitor activity);GO:0005737(cytoplasm);GO:0007049(cell cycle);GO:0007165(signal transduction);GO:0032515(negative regulation of phosphoprotein phosphatase activity);GO:0035556(intracellular signal transduction);GO:0051301(cell division)","NA","K17549","NA","protein phosphatase 1 regulatory inhibitor subunit 1C [Source:HGNC Symbol;Acc:HGNC:14940]",0,0,{"v":0.30686,"d":"0.31"},0,{"v":0.635963,"d":"0.64"},0,{"v":0.482512347416438,"d":"0.48"},{"v":-1.05136223369102,"d":"-1.05"},1,1,"down","no"]
[67070,0,"chr15","+",78264562,78282196,"ENST00000343789",8,2961,"ENSG00000140403","DNAJA4","GO:0005515(protein binding);GO:0005524(ATP binding);GO:0005829(cytosol);GO:0006457(protein folding);GO:0009408(response to heat);GO:0016020(membrane);GO:0031072(heat shock protein binding);GO:0042026(protein refolding);GO:0046872(metal ion binding);GO:0051082(unfolded protein binding);GO:0051087(chaperone binding);GO:0090084(negative regulation of inclusion body assembly)","NA","K09505","NA","DnaJ heat shock protein family (Hsp40) member A4 [Source:HGNC Symbol;Acc:HGNC:14885]",0,0,{"v":0.207282,"d":"0.21"},0,0,0,"inf","inf",1,1,"up","no"]
[102525,0,"chr19","-",35497220,35510431,"ENST00000402589",13,935,"ENSG00000161249","DMKN","GO:0005515(protein binding);GO:0005576(extracellular region);GO:0005615(extracellular space);GO:1903575(cornified envelope assembly)","NA","NA","NA","dermokine [Source:HGNC Symbol;Acc:HGNC:25063]",{"v":0.206416,"d":"0.21"},0,0,0,0,0,"inf","inf",1,1,"up","no"]
[141031,0,"chr3","+",56563516,56565177,"ENST00000473322",2,654,"ENSG00000180376","CCDC66","GO:0001578(microtubule bundle formation);GO:0001750(photoreceptor outer segment);GO:0001895(retina homeostasis);GO:0001917(photoreceptor inner segment);GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0005813(centrosome);GO:0005815(microtubule organizing center);GO:0005856(cytoskeleton);GO:0005874(microtubule);GO:0005929(cilium);GO:0008017(microtubule binding);GO:0030030(cell projection organization);GO:0034451(centriolar satellite);GO:0036064(ciliary basal body);GO:0042803(protein homodimerization activity);GO:0042995(cell projection);GO:0046548(retinal rod cell development);GO:0050908(detection of light stimulus involved in visual perception);GO:0060271(cilium assembly);GO:1903564(regulation of protein localization to cilium)","NA","NA","NA","coiled-coil domain containing 66 [Source:HGNC Symbol;Acc:HGNC:27709]",0,0,{"v":0.055625,"d":"0.06"},0,0,{"v":0.014047,"d":"0.01"},{"v":3.95992026767281,"d":"3.96"},{"v":1.98547138217583,"d":"1.99"},1,1,"up","no"]
[151342,0,"chr4","-",53273579,53365941,"ENST00000611795",5,1320,"ENSG00000184178","SCFD2","GO:0003674(molecular_function);GO:0005575(cellular_component);GO:0006904(vesicle docking involved in exocytosis);GO:0008150(biological_process);GO:0015031(protein transport);GO:0016192(vesicle-mediated transport)","NA","NA","NA","sec1 family domain containing 2 [Source:HGNC Symbol;Acc:HGNC:30676]",0,0,0,0,0,0,1,0,1,1,"no","no"]
[173672,0,"chr6","+",125986479,126039276,"ENST00000368332",13,1889,"ENSG00000066651","TRMT11","GO:0000049(tRNA binding);GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0004809(tRNA (guanine-N2-)-methyltransferase activity);GO:0008033(tRNA processing);GO:0008168(methyltransferase activity);GO:0016740(transferase activity);GO:0030488(tRNA methylation);GO:0032259(methylation)","NA","K15430","EC:2.1.1.214","tRNA methyltransferase 11 homolog [Source:HGNC Symbol;Acc:HGNC:21080]",0,0,0,0,0,0,1,0,1,1,"no","no"]
[46041,0,"chr12","+",78863993,79450279,"ENST00000393240",12,3095,"ENSG00000067715","SYT1","GO:0000149(SNARE binding);GO:0001786(phosphatidylserine binding);GO:0005509(calcium ion binding);GO:0005513(detection of calcium ion);GO:0005515(protein binding);GO:0005516(calmodulin binding);GO:0005543(phospholipid binding);GO:0005544(calcium-dependent phospholipid binding);GO:0005545(1-phosphatidylinositol binding);GO:0005546(phosphatidylinositol-4,5-bisphosphate binding);GO:0005737(cytoplasm);GO:0005794(Golgi apparatus);GO:0005886(plasma membrane);GO:0007268(chemical synaptic transmission);GO:0007269(neurotransmitter secretion);GO:0007420(brain development);GO:0008021(synaptic vesicle);GO:0008022(protein C-terminus binding);GO:0014047(glutamate secretion);GO:0014059(regulation of dopamine secretion);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016079(synaptic vesicle exocytosis);GO:0016192(vesicle-mediated transport);GO:0017075(syntaxin-1 binding);GO:0017156(calcium ion regulated exocytosis);GO:0017157(regulation of exocytosis);GO:0017158(regulation of calcium ion-dependent exocytosis);GO:0019905(syntaxin binding);GO:0030054(cell junction);GO:0030141(secretory granule);GO:0030154(cell differentiation);GO:0030276(clathrin binding);GO:0030285(integral component of synaptic vesicle membrane);GO:0030348(syntaxin-3 binding);GO:0030424(axon);GO:0030658(transport vesicle membrane);GO:0030665(clathrin-coated vesicle membrane);GO:0030672(synaptic vesicle membrane);GO:0031045(dense core granule);GO:0031201(SNARE complex);GO:0031340(positive regulation of vesicle fusion);GO:0031410(cytoplasmic vesicle);GO:0042584(chromaffin granule membrane);GO:0042734(presynaptic membrane);GO:0042802(identical protein binding);GO:0043005(neuron projection);GO:0043229(intracellular organelle);GO:0044306(neuron projection terminus);GO:0045202(synapse);GO:0045956(positive regulation of calcium ion-dependent exocytosis);GO:0046872(metal ion binding);GO:0046982(protein heterodimerization activity);GO:0048278(vesicle docking);GO:0048306(calcium-dependent protein binding);GO:0048488(synaptic vesicle endocytosis);GO:0048791(calcium ion-regulated exocytosis of neurotransmitter);GO:0050750(low-density lipoprotein particle receptor binding);GO:0050806(positive regulation of synaptic transmission);GO:0051260(protein homooligomerization);GO:0051291(protein heterooligomerization);GO:0051592(response to calcium ion);GO:0051966(regulation of synaptic transmission, glutamatergic);GO:0060076(excitatory synapse);GO:0060201(clathrin-sculpted acetylcholine transport vesicle membrane);GO:0060203(clathrin-sculpted glutamate transport vesicle membrane);GO:0061024(membrane organization);GO:0061202(clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane);GO:0061669(spontaneous neurotransmitter secretion);GO:0061891(calcium ion sensor activity);GO:0070083(clathrin-sculpted monoamine transport vesicle membrane);GO:0070382(exocytic vesicle);GO:0071277(cellular response to calcium ion);GO:0071911(synchronous neurotransmitter secretion);GO:0098686(hippocampal mossy fiber to CA3 synapse);GO:0098746(fast, calcium ion-dependent exocytosis of neurotransmitter);GO:0098978(glutamatergic synapse);GO:0099502(calcium-dependent activation of synaptic vesicle fusion);GO:1903235(positive regulation of calcium ion-dependent exocytosis of neurotransmitter);GO:1903305(regulation of regulated secretory pathway);GO:1903861(positive regulation of dendrite extension);GO:2000300(regulation of synaptic vesicle exocytosis)","04721(Synaptic vesicle cycle)","K15290","NA","synaptotagmin 1 [Source:HGNC Symbol;Acc:HGNC:11509]",0,0,0,0,0,0,1,0,1,1,"no","no"]
[126143,0,"chr20","-",34291465,34301948,"ENST00000468908",5,675,"ENSG00000101444","AHCY","GO:0000096(sulfur amino acid metabolic process);GO:0001666(response to hypoxia);GO:0002439(chronic inflammatory response to antigenic stimulus);GO:0004013(adenosylhomocysteinase activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0006730(one-carbon metabolic process);GO:0007584(response to nutrient);GO:0016787(hydrolase activity);GO:0019510(S-adenosylhomocysteine catabolic process);GO:0030554(adenyl nucleotide binding);GO:0032259(methylation);GO:0033353(S-adenosylmethionine cycle);GO:0042470(melanosome);GO:0042745(circadian sleep/wake cycle);GO:0042802(identical protein binding);GO:0043005(neuron projection);GO:0051287(NAD binding);GO:0070062(extracellular exosome)","00270(Cysteine and methionine metabolism)","NA","NA","adenosylhomocysteinase [Source:HGNC Symbol;Acc:HGNC:343]",{"v":0.66521,"d":"0.67"},{"v":0.840663,"d":"0.84"},{"v":0.474948,"d":"0.47"},{"v":1.472319,"d":"1.47"},{"v":0.352477,"d":"0.35"},{"v":0.473132,"d":"0.47"},{"v":0.862003074073687,"d":"0.86"},{"v":-0.214235080627564,"d":"-0.21"},1,1,"down","no"]
[12975,0,"chr1","-",160279484,160284223,"ENST00000462644",7,904,"ENSG00000162735","PEX19","GO:0005515(protein binding);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0005777(peroxisome);GO:0005778(peroxisomal membrane);GO:0005829(cytosol);GO:0006625(protein targeting to peroxisome);GO:0007031(peroxisome organization);GO:0016020(membrane);GO:0016559(peroxisome fission);GO:0031526(brush border membrane);GO:0032991(protein-containing complex);GO:0036105(peroxisome membrane class-1 targeting sequence binding);GO:0045046(protein import into peroxisome membrane);GO:0047485(protein N-terminus binding);GO:0050821(protein stabilization);GO:0051117(ATPase binding);GO:0055085(transmembrane transport);GO:0061077(chaperone-mediated protein folding);GO:0072321(chaperone-mediated protein transport);GO:0072663(establishment of protein localization to peroxisome);GO:1900131(negative regulation of lipid binding)","04146(Peroxisome)","K13337","NA","peroxisomal biogenesis factor 19 [Source:HGNC Symbol;Acc:HGNC:9713]",0,0,0,{"v":0.00132,"d":"0.00"},0,0,"-inf","-inf",1,1,"down","no"]
[98523,0,"chr19","+",9621547,9645489,"ENST00000592851",4,782,"ENSG00000267106","ZNF561-AS1","NA","NA","NA","NA","ZNF561 antisense RNA 1 (head to head) [Source:HGNC Symbol;Acc:HGNC:27613]",{"v":0.061447,"d":"0.06"},{"v":0.072448,"d":"0.07"},{"v":0.031952,"d":"0.03"},{"v":0.225174,"d":"0.23"},{"v":0.053725,"d":"0.05"},0,{"v":0.594648958942126,"d":"0.59"},{"v":-0.749889846046037,"d":"-0.75"},1,1,"down","no"]
[10706,0,"chr1","+",148979795,148993882,"ENST00000491426",4,670,"ENSG00000178104","PDE4DIP","GO:0005515(protein binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005794(Golgi apparatus);GO:0005813(centrosome);GO:0005815(microtubule organizing center);GO:0005856(cytoskeleton);GO:0019899(enzyme binding);GO:0030016(myofibril);GO:0032947(protein-containing complex scaffold activity);GO:0034622(cellular protein-containing complex assembly);GO:1903358(regulation of Golgi organization)","NA","NA","NA","phosphodiesterase 4D interacting protein [Source:HGNC Symbol;Acc:HGNC:15580]",0,0,0,0,{"v":0.13602,"d":"0.14"},0,"-inf","-inf",1,1,"down","no"]
[112354,0,"chr2","-",53670606,53694562,"ENST00000470707",2,764,"ENSG00000115239","ASB3","GO:0005515(protein binding);GO:0005829(cytosol);GO:0016567(protein ubiquitination);GO:0035556(intracellular signal transduction);GO:0043687(post-translational protein modification)","NA","K10325","NA","ankyrin repeat and SOCS box containing 3 [Source:HGNC Symbol;Acc:HGNC:16013]",{"v":0.022389,"d":"0.02"},{"v":0.023648,"d":"0.02"},{"v":0.009677,"d":"0.01"},{"v":0.001381,"d":"0.00"},{"v":0.001305,"d":"0.00"},{"v":0.001005,"d":"0.00"},{"v":15.0945543213221,"d":"15.09"},{"v":3.91595625565341,"d":"3.92"},1,1,"up","no"]
[72887,0,"chr16","+",25111745,25158931,"ENST00000577157",6,522,"ENSG00000205629","LCMT1","GO:0000086(G2/M transition of mitotic cell cycle);GO:0003880(protein C-terminal carboxyl O-methyltransferase activity);GO:0005515(protein binding);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0006464(cellular protein modification process);GO:0006479(protein methylation);GO:0006481(C-terminal protein methylation);GO:0008168(methyltransferase activity);GO:0008276(protein methyltransferase activity);GO:0008757(S-adenosylmethionine-dependent methyltransferase activity);GO:0010906(regulation of glucose metabolic process);GO:0016740(transferase activity);GO:0018423(protein C-terminal leucine carboxyl O-methyltransferase activity);GO:0031333(negative regulation of protein complex assembly);GO:0032259(methylation);GO:0042981(regulation of apoptotic process);GO:0090266(regulation of mitotic cell cycle spindle assembly checkpoint)","NA","K18203","EC:2.1.1.233","leucine carboxyl methyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:17557]",{"v":0.150006,"d":"0.15"},{"v":0.719551,"d":"0.72"},{"v":0.738192,"d":"0.74"},0,{"v":0.562327,"d":"0.56"},0,{"v":2.85909977646458,"d":"2.86"},{"v":1.51556096781753,"d":"1.52"},1,1,"up","no"]
[119386,0,"chr2","+",174395792,174400103,"ENST00000424069",3,548,"ENSG00000144306","SCRN3","GO:0006508(proteolysis);GO:0006887(exocytosis);GO:0016805(dipeptidase activity)","NA","K14358","NA","secernin 3 [Source:HGNC Symbol;Acc:HGNC:30382]",0,{"v":0.445633,"d":"0.45"},0,{"v":0.358659,"d":"0.36"},0,{"v":0.120546,"d":"0.12"},{"v":0.929942300268152,"d":"0.93"},{"v":-0.104786890171445,"d":"-0.10"},1,1,"down","no"]
[144452,0,"chr3","+",133574638,133586682,"ENST00000507408",4,448,"ENSG00000091527","CDV3","GO:0003674(molecular_function);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0008283(cell population proliferation)","NA","NA","NA","CDV3 homolog [Source:HGNC Symbol;Acc:HGNC:26928]",{"v":0.821275,"d":"0.82"},{"v":0.900288,"d":"0.90"},{"v":1.270963,"d":"1.27"},{"v":0.662761,"d":"0.66"},{"v":1.016649,"d":"1.02"},{"v":3.230979,"d":"3.23"},{"v":0.609427481203628,"d":"0.61"},{"v":-0.714473537261606,"d":"-0.71"},1,1,"down","no"]
[164259,0,"chr5","+",149233253,149242584,"ENST00000514212",6,557,"ENSG00000173210","ABLIM3","GO:0001725(stress fiber);GO:0003779(actin binding);GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0006351(transcription, DNA-templated);GO:0007010(cytoskeleton organization);GO:0015629(actin cytoskeleton);GO:0030027(lamellipodium);GO:0030032(lamellipodium assembly);GO:0030036(actin cytoskeleton organization);GO:0045202(synapse);GO:0045944(positive regulation of transcription by RNA polymerase II);GO:0046872(metal ion binding);GO:0051015(actin filament binding);GO:0060271(cilium assembly);GO:0098978(glutamatergic synapse);GO:1903955(positive regulation of protein targeting to mitochondrion)","04360(Axon guidance)","K07520","NA","actin binding LIM protein family member 3 [Source:HGNC Symbol;Acc:HGNC:29132]",{"v":0.025576,"d":"0.03"},0,0,{"v":0.029957,"d":"0.03"},0,0,{"v":0.85375705177421,"d":"0.85"},{"v":-0.228102505212111,"d":"-0.23"},1,1,"down","no"]
[33929,0,"chr11","-",72687260,72689546,"ENST00000542612",4,428,"ENSG00000186635","ARAP1","GO:0001921(positive regulation of receptor recycling);GO:0005096(GTPase activator activity);GO:0005515(protein binding);GO:0005547(phosphatidylinositol-3,4,5-trisphosphate binding);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0005794(Golgi apparatus);GO:0005802(trans-Golgi network);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0007165(signal transduction);GO:0008360(regulation of cell shape);GO:0016020(membrane);GO:0030037(actin filament reorganization involved in cell cycle);GO:0031410(cytoplasmic vesicle);GO:0031702(type 1 angiotensin receptor binding);GO:0032580(Golgi cisterna membrane);GO:0043231(intracellular membrane-bounded organelle);GO:0043547(positive regulation of GTPase activity);GO:0045742(positive regulation of epidermal growth factor receptor signaling pathway);GO:0046872(metal ion binding);GO:0051056(regulation of small GTPase mediated signal transduction);GO:0051270(regulation of cellular component movement);GO:0051491(positive regulation of filopodium assembly);GO:0051497(negative regulation of stress fiber assembly)","04144(Endocytosis)","K18439","NA","ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1 [Source:HGNC Symbol;Acc:HGNC:16925]",{"v":0.172432,"d":"0.17"},{"v":0.388269,"d":"0.39"},{"v":0.28932,"d":"0.29"},{"v":0.083035,"d":"0.08"},{"v":0.169806,"d":"0.17"},{"v":0.082087,"d":"0.08"},{"v":2.53792158314623,"d":"2.54"},{"v":1.34364749338949,"d":"1.34"},1,1,"up","no"]
[38,0,"chr1","-",258568,259024,"ENST00000450734",1,457,"ENSG00000228463","AP006222","NA","NA","NA","NA","ribosomal protein L23a (RPL23A) pseudogene",{"v":0.747792,"d":"0.75"},{"v":1.513992,"d":"1.51"},{"v":0.458908,"d":"0.46"},{"v":1.340259,"d":"1.34"},{"v":0.491901,"d":"0.49"},{"v":1.745676,"d":"1.75"},{"v":0.76042948866298,"d":"0.76"},{"v":-0.395113615606128,"d":"-0.40"},1,1,"down","no"]
[180370,0,"chr7","-",76609994,76618300,"ENST00000441393",4,606,"ENSG00000146707","POMZP3","GO:0003674(molecular_function);GO:0005654(nucleoplasm);GO:0007339(binding of sperm to zona pellucida);GO:0008150(biological_process);GO:0031965(nuclear membrane);GO:0032190(acrosin binding);GO:0035803(egg coat formation);GO:0035804(structural constituent of egg coat);GO:2000344(positive regulation of acrosome reaction)","NA","NA","NA","POM121 and ZP3 fusion [Source:HGNC Symbol;Acc:HGNC:9203]",0,{"v":0.026131,"d":"0.03"},{"v":0.005753,"d":"0.01"},{"v":0.012911,"d":"0.01"},0,{"v":0.071625,"d":"0.07"},{"v":0.37716475820952,"d":"0.38"},{"v":-1.40673321614806,"d":"-1.41"},1,1,"down","no"]
[38934,0,"chr12","+",5433125,5494501,"ENST00000543548",2,516,"ENSG00000185652","NTF3","GO:0000187(activation of MAPK activity);GO:0002092(positive regulation of receptor internalization);GO:0005102(signaling receptor binding);GO:0005165(neurotrophin receptor binding);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0005615(extracellular space);GO:0007165(signal transduction);GO:0007169(transmembrane receptor protein tyrosine kinase signaling pathway);GO:0007267(cell-cell signaling);GO:0007399(nervous system development);GO:0007422(peripheral nervous system development);GO:0007613(memory);GO:0008021(synaptic vesicle);GO:0008083(growth factor activity);GO:0008284(positive regulation of cell population proliferation);GO:0010469(regulation of signaling receptor activity);GO:0010863(positive regulation of phospholipase C activity);GO:0014068(positive regulation of phosphatidylinositol 3-kinase signaling);GO:0021675(nerve development);GO:0030335(positive regulation of cell migration);GO:0030424(axon);GO:0030425(dendrite);GO:0031410(cytoplasmic vesicle);GO:0032148(activation of protein kinase B activity);GO:0033138(positive regulation of peptidyl-serine phosphorylation);GO:0038180(nerve growth factor signaling pathway);GO:0042056(chemoattractant activity);GO:0042981(regulation of apoptotic process);GO:0043524(negative regulation of neuron apoptotic process);GO:0045664(regulation of neuron differentiation);GO:0048812(neuron projection morphogenesis);GO:0050731(positive regulation of peptidyl-tyrosine phosphorylation);GO:0050732(negative regulation of peptidyl-tyrosine phosphorylation);GO:0050804(modulation of chemical synaptic transmission);GO:0050918(positive chemotaxis);GO:0050930(induction of positive chemotaxis);GO:0051388(positive regulation of neurotrophin TRK receptor signaling pathway);GO:0090630(activation of GTPase activity);GO:2000251(positive regulation of actin cytoskeleton reorganization)","04010(MAPK signaling pathway);04014(Ras signaling pathway);04151(PI3K-Akt signaling pathway);04722(Neurotrophin signaling pathway)","K04356","NA","neurotrophin 3 [Source:HGNC Symbol;Acc:HGNC:8023]",{"v":0.298294,"d":"0.30"},0,{"v":0.274808,"d":"0.27"},{"v":0.35105,"d":"0.35"},{"v":0.169545,"d":"0.17"},{"v":0.047538,"d":"0.05"},{"v":1.00874619147277,"d":"1.01"},{"v":0.012563226609655,"d":"0.01"},1,1,"up","no"]
[71927,0,"chr16","+",16076174,16111461,"ENST00000575422",8,1198,"ENSG00000103222","ABCC1","GO:0000166(nucleotide binding);GO:0004012(phospholipid-translocating ATPase activity);GO:0005215(transporter activity);GO:0005524(ATP binding);GO:0005774(vacuolar membrane);GO:0005886(plasma membrane);GO:0005887(integral component of plasma membrane);GO:0006691(leukotriene metabolic process);GO:0006855(drug transmembrane transport);GO:0008559(xenobiotic transmembrane transporting ATPase activity);GO:0009235(cobalamin metabolic process);GO:0015420(cobalamin-transporting ATPase activity);GO:0015889(cobalamin transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016323(basolateral plasma membrane);GO:0016787(hydrolase activity);GO:0016887(ATPase activity);GO:0022857(transmembrane transporter activity);GO:0034634(glutathione transmembrane transporter activity);GO:0034775(glutathione transmembrane transport);GO:0042493(response to drug);GO:0042626(ATPase activity, coupled to transmembrane movement of substances);GO:0042908(xenobiotic transport);GO:0045332(phospholipid translocation);GO:0046623(sphingolipid-translocating ATPase activity);GO:0055085(transmembrane transport);GO:0060326(cell chemotaxis);GO:0070062(extracellular exosome);GO:0099039(sphingolipid translocation)","01523(Antifolate resistance);02010(ABC transporters);04071(Sphingolipid signaling pathway);04977(Vitamin digestion and absorption);05206(MicroRNAs in cancer)","K05665","EC:7.6.2.3","ATP binding cassette subfamily C member 1 [Source:HGNC Symbol;Acc:HGNC:51]",{"v":0.005491,"d":"0.01"},{"v":0.005882,"d":"0.01"},{"v":0.121233,"d":"0.12"},{"v":0.103704,"d":"0.10"},{"v":0.016133,"d":"0.02"},{"v":0.139117,"d":"0.14"},{"v":0.512083227136866,"d":"0.51"},{"v":-0.965549789311111,"d":"-0.97"},1,1,"down","no"]
[140199,0,"chr3","+",50090370,50100004,"ENST00000417905",4,427,"ENSG00000003756","RBM5","GO:0000245(spliceosomal complex assembly);GO:0000381(regulation of alternative mRNA splicing, via spliceosome);GO:0000398(mRNA splicing, via spliceosome);GO:0003676(nucleic acid binding);GO:0003677(DNA binding);GO:0003723(RNA binding);GO:0003729(mRNA binding);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005681(spliceosomal complex);GO:0006396(RNA processing);GO:0006397(mRNA processing);GO:0006915(apoptotic process);GO:0008285(negative regulation of cell population proliferation);GO:0008380(RNA splicing);GO:0042981(regulation of apoptotic process);GO:0043065(positive regulation of apoptotic process);GO:0046872(metal ion binding)","NA","K13094","NA","RNA binding motif protein 5 [Source:HGNC Symbol;Acc:HGNC:9902]",{"v":0.283713,"d":"0.28"},{"v":0.08706,"d":"0.09"},{"v":0.418206,"d":"0.42"},{"v":0.194072,"d":"0.19"},{"v":0.01266,"d":"0.01"},{"v":0.345456,"d":"0.35"},{"v":1.42882315443291,"d":"1.43"},{"v":0.514827364991473,"d":"0.51"},1,1,"up","no"]
[160019,0,"chr5","+",74718291,74721287,"ENST00000513539",5,502,"ENSG00000049860","HEXB","GO:0001501(skeletal system development);GO:0001669(acrosomal vesicle);GO:0004553(hydrolase activity, hydrolyzing O-glycosyl compounds);GO:0004563(beta-N-acetylhexosaminidase activity);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0005615(extracellular space);GO:0005764(lysosome);GO:0005975(carbohydrate metabolic process);GO:0006687(glycosphingolipid metabolic process);GO:0006689(ganglioside catabolic process);GO:0006874(cellular calcium ion homeostasis);GO:0007040(lysosome organization);GO:0007338(single fertilization);GO:0007341(penetration of zona pellucida);GO:0007605(sensory perception of sound);GO:0007626(locomotory behavior);GO:0008049(male courtship behavior);GO:0008152(metabolic process);GO:0008360(regulation of cell shape);GO:0008375(acetylglucosaminyltransferase activity);GO:0008654(phospholipid biosynthetic process);GO:0009313(oligosaccharide catabolic process);GO:0016020(membrane);GO:0016787(hydrolase activity);GO:0016798(hydrolase activity, acting on glycosyl bonds);GO:0019915(lipid storage);GO:0019953(sexual reproduction);GO:0030203(glycosaminoglycan metabolic process);GO:0030207(chondroitin sulfate catabolic process);GO:0030214(hyaluronan catabolic process);GO:0031323(regulation of cellular metabolic process);GO:0035578(azurophil granule lumen);GO:0042340(keratan sulfate catabolic process);GO:0042552(myelination);GO:0042582(azurophil granule);GO:0042803(protein homodimerization activity);GO:0043202(lysosomal lumen);GO:0043312(neutrophil degranulation);GO:0043615(astrocyte cell migration);GO:0044267(cellular protein metabolic process);GO:0045944(positive regulation of transcription by RNA polymerase II);GO:0046982(protein heterodimerization activity);GO:0048477(oogenesis);GO:0050885(neuromuscular process controlling balance);GO:0050905(neuromuscular process);GO:0070062(extracellular exosome);GO:0102148(N-acetyl-beta-D-galactosaminidase activity)","00511(Other glycan degradation);00520(Amino sugar and nucleotide sugar metabolism);00531(Glycosaminoglycan degradation);00603(Glycosphingolipid biosynthesis - globo and isoglobo series);00604(Glycosphingolipid biosynthesis - ganglio series);04142(Lysosome)","K12373","EC:3.2.1.52","hexosaminidase subunit beta [Source:HGNC Symbol;Acc:HGNC:4879]",{"v":0.275509,"d":"0.28"},0,0,0,0,{"v":0.347098,"d":"0.35"},{"v":0.793749891961348,"d":"0.79"},{"v":-0.333243604482866,"d":"-0.33"},1,1,"down","no"]
[35279,0,"chr11","-",93206990,93207583,"ENST00000623456",1,594,"ENSG00000279269","AP003072","NA","NA","NA","NA","novel transcript",0,0,0,0,0,0,1,0,1,1,"no","no"]
[166405,0,"chr5","-",179800938,179806554,"ENST00000523329",5,543,"ENSG00000161013","MGAT4B","GO:0000139(Golgi membrane);GO:0005794(Golgi apparatus);GO:0006486(protein glycosylation);GO:0006487(protein N-linked glycosylation);GO:0006491(N-glycan processing);GO:0008375(acetylglucosaminyltransferase activity);GO:0008454(alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016740(transferase activity);GO:0016757(transferase activity, transferring glycosyl groups);GO:0046872(metal ion binding)","00510(N-Glycan biosynthesis)","K00738","EC:2.4.1.145","alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase B [Source:HGNC Symbol;Acc:HGNC:7048]",{"v":0.4616,"d":"0.46"},{"v":0.406876,"d":"0.41"},{"v":0.364636,"d":"0.36"},{"v":0.43025,"d":"0.43"},{"v":0.335048,"d":"0.34"},{"v":0.256172,"d":"0.26"},{"v":1.2071935543873,"d":"1.21"},{"v":0.271657007963403,"d":"0.27"},1,1,"up","no"]
[104965,0,"chr19","-",44329695,44401608,"ENST00000588212",5,561,"ENSG00000267173","AC245748","GO:0003676(nucleic acid binding);GO:0005622(intracellular);GO:0005634(nucleus);GO:0006355(regulation of transcription, DNA-templated)","NA","NA","NA","novel protein",0,0,0,0,{"v":0.120495,"d":"0.12"},0,"-inf","-inf",1,1,"down","no"]
[121960,0,"chr2","-",218277363,218282181,"ENST00000439306",7,631,"ENSG00000135926","TMBIM1","GO:0005123(death receptor binding);GO:0005764(lysosome);GO:0005765(lysosomal membrane);GO:0005768(endosome);GO:0005794(Golgi apparatus);GO:0005886(plasma membrane);GO:0010008(endosome membrane);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0035579(specific granule membrane);GO:0043086(negative regulation of catalytic activity);GO:0043231(intracellular membrane-bounded organelle);GO:0043312(neutrophil degranulation);GO:0070062(extracellular exosome);GO:1902042(negative regulation of extrinsic apoptotic signaling pathway via death domain receptors);GO:1902045(negative regulation of Fas signaling pathway);GO:1903077(negative regulation of protein localization to plasma membrane);GO:2000504(positive regulation of blood vessel remodeling)","NA","K06890","NA","transmembrane BAX inhibitor motif containing 1 [Source:HGNC Symbol;Acc:HGNC:23410]",{"v":0.256038,"d":"0.26"},{"v":0.050053,"d":"0.05"},{"v":0.154656,"d":"0.15"},{"v":0.072801,"d":"0.07"},{"v":0.101468,"d":"0.10"},{"v":0.202531,"d":"0.20"},{"v":1.22278927813163,"d":"1.22"},{"v":0.290175807309605,"d":"0.29"},1,1,"up","no"]
[139884,0,"chr3","-",49271406,49277219,"ENST00000436325",4,581,"ENSG00000188315","C3orf62","GO:0005515(protein binding)","NA","NA","NA","chromosome 3 open reading frame 62 [Source:HGNC Symbol;Acc:HGNC:24771]",0,0,{"v":0.275803,"d":"0.28"},0,0,0,"inf","inf",1,1,"up","no"]
[192146,0,"chr8","-",119557087,119581107,"ENST00000523861",7,3647,"ENSG00000136960","ENPP2","GO:0003676(nucleic acid binding);GO:0003824(catalytic activity);GO:0004528(phosphodiesterase I activity);GO:0004551(nucleotide diphosphatase activity);GO:0004622(lysophospholipase activity);GO:0005044(scavenger receptor activity);GO:0005509(calcium ion binding);GO:0005576(extracellular region);GO:0005615(extracellular space);GO:0005886(plasma membrane);GO:0006629(lipid metabolic process);GO:0006644(phospholipid metabolic process);GO:0006898(receptor-mediated endocytosis);GO:0006935(chemotaxis);GO:0006955(immune response);GO:0008134(transcription factor binding);GO:0008270(zinc ion binding);GO:0009395(phospholipid catabolic process);GO:0010634(positive regulation of epithelial cell migration);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016042(lipid catabolic process);GO:0016787(hydrolase activity);GO:0030247(polysaccharide binding);GO:0030334(regulation of cell migration);GO:0034638(phosphatidylcholine catabolic process);GO:0045765(regulation of angiogenesis);GO:0046872(metal ion binding);GO:0047391(alkylglycerophosphoethanolamine phosphodiesterase activity);GO:0048870(cell motility);GO:0050731(positive regulation of peptidyl-tyrosine phosphorylation);GO:0090305(nucleic acid phosphodiester bond hydrolysis);GO:2000394(positive regulation of lamellipodium morphogenesis)","00565(Ether lipid metabolism)","NA","NA","ectonucleotide pyrophosphatase/phosphodiesterase 2 [Source:HGNC Symbol;Acc:HGNC:3357]",{"v":0.189585,"d":"0.19"},{"v":2.063632,"d":"2.06"},{"v":0.078719,"d":"0.08"},{"v":0.037789,"d":"0.04"},{"v":0.183396,"d":"0.18"},{"v":0.137868,"d":"0.14"},{"v":6.49468462873169,"d":"6.49"},{"v":2.69925947246125,"d":"2.70"},1,1,"up","no"]
[162819,0,"chr5","+",134874371,134900039,"ENST00000511070",4,1006,"ENSG00000113621","TXNDC15","GO:0005623(cell);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0045454(cell redox homeostasis)","NA","NA","NA","thioredoxin domain containing 15 [Source:HGNC Symbol;Acc:HGNC:20652]",{"v":1.168682,"d":"1.17"},{"v":0.33192,"d":"0.33"},{"v":0.175931,"d":"0.18"},{"v":0.630569,"d":"0.63"},0,0,{"v":2.65876216559964,"d":"2.66"},{"v":1.41075472948736,"d":"1.41"},1,1,"up","no"]
[174850,0,"chr6","+",149578923,149582283,"ENST00000433539",4,563,"ENSG00000055211","GINM1","GO:0016020(membrane);GO:0016021(integral component of membrane)","NA","NA","NA","glycoprotein integral membrane 1 [Source:HGNC Symbol;Acc:HGNC:21074]",{"v":0.135573,"d":"0.14"},{"v":0.144842,"d":"0.14"},{"v":0.174767,"d":"0.17"},{"v":0.164951,"d":"0.16"},{"v":0.053611,"d":"0.05"},{"v":0.189993,"d":"0.19"},{"v":1.11412661697935,"d":"1.11"},{"v":0.155913199740688,"d":"0.16"},1,1,"up","no"]
[111608,0,"chr2","-",38798352,38803023,"ENST00000477981",2,400,"ENSG00000163214","DHX57","GO:0000166(nucleotide binding);GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0004386(helicase activity);GO:0005515(protein binding);GO:0005524(ATP binding);GO:0016787(hydrolase activity);GO:0034459(ATP-dependent 3'-5' RNA helicase activity);GO:0046872(metal ion binding)","NA","K13026","EC:3.6.4.13","DExH-box helicase 57 [Source:HGNC Symbol;Acc:HGNC:20086]",{"v":0.091043,"d":"0.09"},{"v":0.226317,"d":"0.23"},{"v":0.149997,"d":"0.15"},{"v":0.226199,"d":"0.23"},{"v":0.11685,"d":"0.12"},{"v":0.0974,"d":"0.10"},{"v":1.06109220363765,"d":"1.06"},{"v":0.0855500247269104,"d":"0.09"},1,1,"up","no"]
[172851,0,"chr6","+",107028569,107051335,"ENST00000625458",5,1146,"ENSG00000130349","C6orf203","GO:0005739(mitochondrion)","NA","NA","NA","chromosome 6 open reading frame 203 [Source:HGNC Symbol;Acc:HGNC:17971]",{"v":0.501935,"d":"0.50"},{"v":0.216856,"d":"0.22"},{"v":0.215507,"d":"0.22"},{"v":0.523111,"d":"0.52"},{"v":0.015395,"d":"0.02"},{"v":0.250695,"d":"0.25"},{"v":1.18385303617203,"d":"1.18"},{"v":0.24348999553982,"d":"0.24"},1,1,"up","no"]
[55146,0,"chr14","+",24172080,24180254,"ENST00000611366",19,2276,"ENSG00000100918","REC8","GO:0000724(double-strand break repair via homologous recombination);GO:0000775(chromosome, centromeric region);GO:0000778(condensed nuclear chromosome kinetochore);GO:0000780(condensed nuclear chromosome, centromeric region);GO:0000793(condensed chromosome);GO:0000794(condensed nuclear chromosome);GO:0000795(synaptonemal complex);GO:0000800(lateral element);GO:0001556(oocyte maturation);GO:0001673(male germ cell nucleus);GO:0003682(chromatin binding);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005694(chromosome);GO:0006302(double-strand break repair);GO:0007059(chromosome segregation);GO:0007062(sister chromatid cohesion);GO:0007129(synapsis);GO:0007130(synaptonemal complex assembly);GO:0007131(reciprocal meiotic recombination);GO:0007141(male meiosis I);GO:0007283(spermatogenesis);GO:0007286(spermatid development);GO:0008278(cohesin complex);GO:0009566(fertilization);GO:0030893(meiotic cohesin complex);GO:0034991(nuclear meiotic cohesin complex);GO:0051321(meiotic cell cycle);GO:0072520(seminiferous tubule development)","04114(Oocyte meiosis)","K13054","NA","REC8 meiotic recombination protein [Source:HGNC Symbol;Acc:HGNC:16879]",0,0,{"v":0.249861,"d":"0.25"},0,{"v":0.203462,"d":"0.20"},{"v":0.269574,"d":"0.27"},{"v":0.528207155480767,"d":"0.53"},{"v":-0.920824249446926,"d":"-0.92"},1,1,"down","no"]
[4040,0,"chr1","+",32816767,32826489,"ENST00000530710",3,725,"ENSG00000116497","S100PBP","GO:0005634(nucleus);GO:0005829(cytosol);GO:0016607(nuclear speck);GO:0048306(calcium-dependent protein binding)","NA","NA","NA","S100P binding protein [Source:HGNC Symbol;Acc:HGNC:25768]",{"v":0.083676,"d":"0.08"},{"v":0.076101,"d":"0.08"},0,{"v":0.067265,"d":"0.07"},{"v":1.013135,"d":"1.01"},0,{"v":0.147886893743058,"d":"0.15"},{"v":-2.75743389349657,"d":"-2.76"},1,1,"down","no"]
[176443,0,"chr7","+",5428731,5429672,"ENST00000608012",1,942,"ENSG00000273084","AC092171","NA","NA","NA","NA","novel transcript",{"v":0.33432,"d":"0.33"},{"v":0.58364,"d":"0.58"},{"v":0.621512,"d":"0.62"},{"v":0.289668,"d":"0.29"},{"v":0.165212,"d":"0.17"},{"v":0.164752,"d":"0.16"},{"v":2.48449402225837,"d":"2.48"},{"v":1.31295207073947,"d":"1.31"},1,1,"up","no"]
[75402,0,"chr16","-",57429177,57430646,"ENST00000564885",2,493,"ENSG00000005194","CIAPIN1","GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005730(nucleolus);GO:0005737(cytoplasm);GO:0005739(mitochondrion);GO:0005758(mitochondrial intermembrane space);GO:0006915(apoptotic process);GO:0008168(methyltransferase activity);GO:0009055(electron transfer activity);GO:0016226(iron-sulfur cluster assembly);GO:0022900(electron transport chain);GO:0030097(hemopoiesis);GO:0032259(methylation);GO:0043066(negative regulation of apoptotic process);GO:0046872(metal ion binding);GO:0051536(iron-sulfur cluster binding);GO:0051537(2 iron, 2 sulfur cluster binding);GO:0051539(4 iron, 4 sulfur cluster binding)","NA","K22746","NA","cytokine induced apoptosis inhibitor 1 [Source:HGNC Symbol;Acc:HGNC:28050]",{"v":0.363562,"d":"0.36"},{"v":0.140372,"d":"0.14"},{"v":0.258446,"d":"0.26"},{"v":0.323131,"d":"0.32"},{"v":0.196526,"d":"0.20"},{"v":0.345383,"d":"0.35"},{"v":0.88132340701008,"d":"0.88"},{"v":-0.18225657282182,"d":"-0.18"},1,1,"down","no"]
[87756,0,"chr17","+",50561460,50626766,"ENST00000503485",36,6768,"ENSG00000006283","CACNA1G","GO:0001508(action potential);GO:0002027(regulation of heart rate);GO:0005216(ion channel activity);GO:0005244(voltage-gated ion channel activity);GO:0005245(voltage-gated calcium channel activity);GO:0005262(calcium channel activity);GO:0005737(cytoplasm);GO:0005886(plasma membrane);GO:0005891(voltage-gated calcium channel complex);GO:0006811(ion transport);GO:0006816(calcium ion transport);GO:0007268(chemical synaptic transmission);GO:0008332(low voltage-gated calcium channel activity);GO:0010045(response to nickel cation);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0019228(neuronal action potential);GO:0034220(ion transmembrane transport);GO:0034765(regulation of ion transmembrane transport);GO:0042391(regulation of membrane potential);GO:0045956(positive regulation of calcium ion-dependent exocytosis);GO:0055085(transmembrane transport);GO:0060371(regulation of atrial cardiac muscle cell membrane depolarization);GO:0070509(calcium ion import);GO:0070588(calcium ion transmembrane transport);GO:0086002(cardiac muscle cell action potential involved in contraction);GO:0086010(membrane depolarization during action potential);GO:0086015(SA node cell action potential);GO:0086016(AV node cell action potential);GO:0086018(SA node cell to atrial cardiac muscle cell signaling);GO:0086027(AV node cell to bundle of His cell signaling);GO:0086045(membrane depolarization during AV node cell action potential);GO:0086046(membrane depolarization during SA node cell action potential);GO:0086056(voltage-gated calcium channel activity involved in AV node cell action potential);GO:0086059(voltage-gated calcium channel activity involved SA node cell action potential);GO:0086091(regulation of heart rate by cardiac conduction);GO:0097110(scaffold protein binding)","04010(MAPK signaling pathway);04020(Calcium signaling pathway);04713(Circadian entrainment);04925(Aldosterone synthesis and secretion);04927(Cortisol synthesis and secretion);04930(Type II diabetes mellitus);04934(Cushing syndrome)","K04854","NA","calcium voltage-gated channel subunit alpha1 G [Source:HGNC Symbol;Acc:HGNC:1394]",{"v":0.006259,"d":"0.01"},0,0,0,0,{"v":0.011312,"d":"0.01"},{"v":0.553306223479491,"d":"0.55"},{"v":-0.85384994386552,"d":"-0.85"},1,1,"down","no"]
[108684,0,"chr19","-",56822497,56824314,"ENST00000593931",3,483,"ENSG00000269699","ZIM2","GO:0000981(DNA-binding transcription factor activity, RNA polymerase II-specific);GO:0003676(nucleic acid binding);GO:0003677(DNA binding);GO:0003700(DNA-binding transcription factor activity);GO:0005575(cellular_component);GO:0005622(intracellular);GO:0005634(nucleus);GO:0006355(regulation of transcription, DNA-templated);GO:0006357(regulation of transcription by RNA polymerase II);GO:0008270(zinc ion binding);GO:0046872(metal ion binding)","NA","K09229","NA","zinc finger imprinted 2 [Source:HGNC Symbol;Acc:HGNC:12875]",0,0,{"v":0.045786,"d":"0.05"},{"v":0.078413,"d":"0.08"},0,0,{"v":0.583908280514711,"d":"0.58"},{"v":-0.77618632447832,"d":"-0.78"},1,1,"down","no"]
[26492,0,"chr11","-",3580927,3581135,"ENST00000641667",1,209,"ENSG00000284639","AP006294","NA","NA","NA","NA","RNA binding protein, fox-1 homolog (C. elegans) 1 (RBFOX1) pseudogene",0,0,0,0,0,0,1,0,1,1,"no","no"]
[67017,0,"chr15","-",78105147,78111251,"ENST00000643268",4,744,"ENSG00000136425","CIB2","GO:0000287(magnesium ion binding);GO:0001750(photoreceptor outer segment);GO:0001917(photoreceptor inner segment);GO:0005178(integrin binding);GO:0005509(calcium ion binding);GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0005886(plasma membrane);GO:0005927(muscle tendon junction);GO:0005929(cilium);GO:0007204(positive regulation of cytosolic calcium ion concentration);GO:0016020(membrane);GO:0031594(neuromuscular junction);GO:0032420(stereocilium);GO:0032437(cuticular plate);GO:0042383(sarcolemma);GO:0042803(protein homodimerization activity);GO:0042995(cell projection);GO:0044877(protein-containing complex binding);GO:0045494(photoreceptor cell maintenance);GO:0046872(metal ion binding);GO:0055074(calcium ion homeostasis);GO:0071318(cellular response to ATP);GO:0072562(blood microparticle)","NA","NA","NA","calcium and integrin binding family member 2 [Source:HGNC Symbol;Acc:HGNC:24579]",{"v":0.109048,"d":"0.11"},{"v":0.393175,"d":"0.39"},{"v":0.374092,"d":"0.37"},{"v":0.368201,"d":"0.37"},{"v":0.720636,"d":"0.72"},{"v":0.234303,"d":"0.23"},{"v":0.662299529906132,"d":"0.66"},{"v":-0.594444260667012,"d":"-0.59"},1,1,"down","no"]
[55273,0,"chr14","-",24239647,24242674,"ENST00000626689",7,1643,"ENSG00000092330","TINF2","GO:0000781(chromosome, telomeric region);GO:0000783(nuclear telomere cap complex);GO:0000784(nuclear chromosome, telomeric region);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005694(chromosome);GO:0010370(perinucleolar chromocenter);GO:0010836(negative regulation of protein ADP-ribosylation);GO:0016233(telomere capping);GO:0016363(nuclear matrix);GO:0016604(nuclear body);GO:0032202(telomere assembly);GO:0032211(negative regulation of telomere maintenance via telomerase);GO:0042162(telomeric DNA binding);GO:0050680(negative regulation of epithelial cell proliferation);GO:0070187(shelterin complex);GO:0070198(protein localization to chromosome, telomeric region);GO:1904356(regulation of telomere maintenance via telomere lengthening)","NA","K11112","NA","TERF1 interacting nuclear factor 2 [Source:HGNC Symbol;Acc:HGNC:11824]",{"v":0.356508,"d":"0.36"},{"v":0.032493,"d":"0.03"},{"v":0.334453,"d":"0.33"},{"v":0.407509,"d":"0.41"},{"v":0.210471,"d":"0.21"},{"v":0.357143,"d":"0.36"},{"v":0.741910507700054,"d":"0.74"},{"v":-0.43068292136192,"d":"-0.43"},1,1,"down","no"]
[4294,0,"chr1","-",35716160,35716911,"ENST00000503824",2,578,"ENSG00000142686","C1orf216","GO:0005515(protein binding)","NA","NA","NA","chromosome 1 open reading frame 216 [Source:HGNC Symbol;Acc:HGNC:26800]",{"v":0.305221,"d":"0.31"},{"v":0.285628,"d":"0.29"},{"v":0.580563,"d":"0.58"},{"v":0.392871,"d":"0.39"},{"v":0.255401,"d":"0.26"},{"v":0.228497,"d":"0.23"},{"v":1.33605544904074,"d":"1.34"},{"v":0.417979883856931,"d":"0.42"},1,1,"up","no"]
[135170,0,"chr22","+",41998788,42028475,"ENST00000328823",6,2255,"ENSG00000183066","WBP2NL","GO:0003713(transcription coactivator activity);GO:0005634(nucleus);GO:0007343(egg activation);GO:0031490(chromatin DNA binding);GO:0033011(perinuclear theca);GO:0035038(female pronucleus assembly);GO:0035039(male pronucleus assembly);GO:0036126(sperm flagellum);GO:0050699(WW domain binding);GO:0051321(meiotic cell cycle);GO:0061827(sperm head);GO:1903508(positive regulation of nucleic acid-templated transcription)","NA","K22532","NA","WBP2 N-terminal like [Source:HGNC Symbol;Acc:HGNC:28389]",0,0,0,0,0,{"v":0.098319,"d":"0.10"},"-inf","-inf",1,1,"down","no"]
[140380,0,"chr3","-",50362802,50503597,"ENST00000266039",38,5476,"ENSG00000007402","CACNA2D2","GO:0005244(voltage-gated ion channel activity);GO:0005245(voltage-gated calcium channel activity);GO:0005262(calcium channel activity);GO:0005886(plasma membrane);GO:0005891(voltage-gated calcium channel complex);GO:0006811(ion transport);GO:0006816(calcium ion transport);GO:0007528(neuromuscular junction development);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0034765(regulation of ion transmembrane transport);GO:0040014(regulation of multicellular organism growth);GO:0046622(positive regulation of organ growth);GO:0046872(metal ion binding);GO:0048747(muscle fiber development);GO:0050796(regulation of insulin secretion);GO:0060024(rhythmic synaptic transmission);GO:0061337(cardiac conduction);GO:0070588(calcium ion transmembrane transport)","04010(MAPK signaling pathway);04260(Cardiac muscle contraction);04261(Adrenergic signaling in cardiomyocytes);04921(Oxytocin signaling pathway);05410(Hypertrophic cardiomyopathy (HCM));05412(Arrhythmogenic right ventricular cardiomyopathy (ARVC));05414(Dilated cardiomyopathy (DCM))","K04859","NA","calcium voltage-gated channel auxiliary subunit alpha2delta 2 [Source:HGNC Symbol;Acc:HGNC:1400]",{"v":0.093928,"d":"0.09"},{"v":0.098253,"d":"0.10"},0,{"v":0.088954,"d":"0.09"},{"v":0.03474,"d":"0.03"},{"v":0.115498,"d":"0.12"},{"v":0.803459145790829,"d":"0.80"},{"v":-0.31570342713315,"d":"-0.32"},1,1,"down","no"]
[173146,0,"chr6","-",111348953,111351733,"ENST00000492520",2,442,"ENSG00000009413","REV3L","GO:0000166(nucleotide binding);GO:0003676(nucleic acid binding);GO:0003677(DNA binding);GO:0003887(DNA-directed DNA polymerase activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005730(nucleolus);GO:0006260(DNA replication);GO:0006261(DNA-dependent DNA replication);GO:0006281(DNA repair);GO:0006974(cellular response to DNA damage stimulus);GO:0016035(zeta DNA polymerase complex);GO:0016740(transferase activity);GO:0016779(nucleotidyltransferase activity);GO:0019985(translesion synthesis);GO:0042276(error-prone translesion synthesis);GO:0046872(metal ion binding);GO:0051536(iron-sulfur cluster binding);GO:0051539(4 iron, 4 sulfur cluster binding);GO:0090305(nucleic acid phosphodiester bond hydrolysis)","01524(Platinum drug resistance);03460(Fanconi anemia pathway)","K02350","EC:2.7.7.7","REV3 like, DNA directed polymerase zeta catalytic subunit [Source:HGNC Symbol;Acc:HGNC:9968]",{"v":0.316162,"d":"0.32"},{"v":0.054118,"d":"0.05"},{"v":0.158901,"d":"0.16"},{"v":0.205373,"d":"0.21"},{"v":0.153704,"d":"0.15"},{"v":0.1791,"d":"0.18"},{"v":0.983284309808855,"d":"0.98"},{"v":-0.0243194727809618,"d":"-0.02"},1,1,"down","no"]
[167507,0,"chr6","-",13306398,13328531,"ENST00000452989",6,938,"ENSG00000145979","TBC1D7","GO:0005096(GTPase activator activity);GO:0005515(protein binding);GO:0005829(cytosol);GO:0017137(Rab GTPase binding);GO:0031398(positive regulation of protein ubiquitination);GO:0031410(cytoplasmic vesicle);GO:0032007(negative regulation of TOR signaling);GO:0036064(ciliary basal body);GO:0043547(positive regulation of GTPase activity);GO:0070848(response to growth factor);GO:0090630(activation of GTPase activity);GO:1902018(negative regulation of cilium assembly)","04150(mTOR signaling pathway)","K20396","NA","TBC1 domain family member 7 [Source:HGNC Symbol;Acc:HGNC:21066]",0,{"v":0.152769,"d":"0.15"},0,{"v":0.367831,"d":"0.37"},{"v":0.362653,"d":"0.36"},{"v":0.258926,"d":"0.26"},{"v":0.154404139840915,"d":"0.15"},{"v":-2.69521666062404,"d":"-2.70"},1,1,"down","no"]
[6762,0,"chr1","+",59020366,59132795,"ENST00000634569",6,1030,"ENSG00000237352","LINC01358","NA","NA","NA","NA","long intergenic non-protein coding RNA 1358 [Source:HGNC Symbol;Acc:HGNC:50589]",{"v":0.061151,"d":"0.06"},0,{"v":0.020327,"d":"0.02"},0,{"v":0.125914,"d":"0.13"},{"v":0.054389,"d":"0.05"},{"v":0.451894865864683,"d":"0.45"},{"v":-1.1459409287473,"d":"-1.15"},1,1,"down","no"]
[134189,0,"chr22","+",36253164,36261633,"ENST00000431184",6,550,"ENSG00000100342","APOL1","GO:0005254(chloride channel activity);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0005615(extracellular space);GO:0005788(endoplasmic reticulum lumen);GO:0006629(lipid metabolic process);GO:0006869(lipid transport);GO:0006898(receptor-mediated endocytosis);GO:0008202(steroid metabolic process);GO:0008203(cholesterol metabolic process);GO:0008289(lipid binding);GO:0019835(cytolysis);GO:0031224(intrinsic component of membrane);GO:0031640(killing of cells of other organism);GO:0034361(very-low-density lipoprotein particle);GO:0034364(high-density lipoprotein particle);GO:0042157(lipoprotein metabolic process);GO:0043687(post-translational protein modification);GO:0044267(cellular protein metabolic process);GO:0045087(innate immune response);GO:0072562(blood microparticle);GO:1902476(chloride transmembrane transport)","05143(African trypanosomiasis)","K14480","NA","apolipoprotein L1 [Source:HGNC Symbol;Acc:HGNC:618]",0,0,0,{"v":0.020308,"d":"0.02"},0,0,"-inf","-inf",1,1,"down","no"]
[75871,0,"chr16","-",63531088,63618046,"ENST00000564290",2,571,"ENSG00000260658","AC138305","NA","NA","NA","NA","novel transcript",{"v":0.03351,"d":"0.03"},{"v":0.077072,"d":"0.08"},{"v":0.042051,"d":"0.04"},0,{"v":0.136278,"d":"0.14"},{"v":0.310626,"d":"0.31"},{"v":0.341534199738646,"d":"0.34"},{"v":-1.5498980439769,"d":"-1.55"},1,1,"down","no"]
[202300,0,"chrX","+",38221391,38223667,"ENST00000423919",2,655,"ENSG00000226679","AL606748","NA","NA","NA","NA","novel transcript",{"v":0.055774,"d":"0.06"},{"v":0.120543,"d":"0.12"},0,0,{"v":0.091219,"d":"0.09"},{"v":0.166363,"d":"0.17"},{"v":0.684508234271028,"d":"0.68"},{"v":-0.546860198443595,"d":"-0.55"},1,1,"down","no"]
[32661,0,"chr11","+",66230380,66243282,"ENST00000529757",13,1688,"ENSG00000175115","PACS1","GO:0005515(protein binding);GO:0005794(Golgi apparatus);GO:0005829(cytosol);GO:0016032(viral process);GO:0030137(COPI-coated vesicle);GO:0034067(protein localization to Golgi apparatus);GO:0044325(ion channel binding);GO:0050690(regulation of defense response to virus by virus);GO:0072659(protein localization to plasma membrane)","NA","K23290","NA","phosphofurin acidic cluster sorting protein 1 [Source:HGNC Symbol;Acc:HGNC:30032]",{"v":0.295735,"d":"0.30"},{"v":0.353558,"d":"0.35"},{"v":0.309632,"d":"0.31"},{"v":0.329946,"d":"0.33"},{"v":0.284836,"d":"0.28"},{"v":0.113088,"d":"0.11"},{"v":1.31743992745957,"d":"1.32"},{"v":0.39773717944728,"d":"0.40"},1,1,"up","no"]
[173254,0,"chr6","-",112171630,112179502,"ENST00000521187",3,2725,"ENSG00000112769","LAMA4","GO:0001568(blood vessel development);GO:0005102(signaling receptor binding);GO:0005201(extracellular matrix structural constituent);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0005604(basement membrane);GO:0007155(cell adhesion);GO:0030155(regulation of cell adhesion);GO:0030198(extracellular matrix organization);GO:0030334(regulation of cell migration);GO:0031594(neuromuscular junction);GO:0043083(synaptic cleft);GO:0045995(regulation of embryonic development);GO:0050873(brown fat cell differentiation);GO:0062023(collagen-containing extracellular matrix);GO:0070062(extracellular exosome);GO:0120163(negative regulation of cold-induced thermogenesis)","04151(PI3K-Akt signaling pathway);04510(Focal adhesion);04512(ECM-receptor interaction);05143(African trypanosomiasis);05145(Toxoplasmosis);05146(Amoebiasis);05165(Human papillomavirus infection);05200(Pathways in cancer);05222(Small cell lung cancer)","NA","NA","laminin subunit alpha 4 [Source:HGNC Symbol;Acc:HGNC:6484]",{"v":0.121666,"d":"0.12"},{"v":0.170617,"d":"0.17"},{"v":0.326413,"d":"0.33"},{"v":0.072015,"d":"0.07"},{"v":0.098962,"d":"0.10"},{"v":0.106221,"d":"0.11"},{"v":2.23196415558554,"d":"2.23"},{"v":1.15831385827184,"d":"1.16"},1,1,"up","no"]
[131570,0,"chr22","+",17628916,17702428,"ENST00000399782",7,1381,"ENSG00000099968","BCL2L13","GO:0005515(protein binding);GO:0005634(nucleus);GO:0005739(mitochondrion);GO:0006915(apoptotic process);GO:0006919(activation of cysteine-type endopeptidase activity involved in apoptotic process);GO:0008656(cysteine-type endopeptidase activator activity involved in apoptotic process);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0031966(mitochondrial membrane);GO:0042981(regulation of apoptotic process)","04137(Mitophagy - animal);05134(Legionellosis)","K15485","NA","BCL2 like 13 [Source:HGNC Symbol;Acc:HGNC:17164]",0,{"v":0.172088,"d":"0.17"},{"v":0.237355,"d":"0.24"},{"v":0.014034,"d":"0.01"},{"v":0.077818,"d":"0.08"},{"v":0.007322,"d":"0.01"},{"v":4.12853167160748,"d":"4.13"},{"v":2.04562877274754,"d":"2.05"},1,1,"up","no"]
[4796,0,"chr1","-",40311500,40316702,"ENST00000496215",11,668,"ENSG00000049089","COL9A2","GO:0001501(skeletal system development);GO:0005201(extracellular matrix structural constituent);GO:0005576(extracellular region);GO:0005581(collagen trimer);GO:0005594(collagen type IX trimer);GO:0005604(basement membrane);GO:0005615(extracellular space);GO:0005788(endoplasmic reticulum lumen);GO:0030020(extracellular matrix structural constituent conferring tensile strength);GO:0030198(extracellular matrix organization);GO:0031012(extracellular matrix);GO:0062023(collagen-containing extracellular matrix)","04151(PI3K-Akt signaling pathway);04510(Focal adhesion);04512(ECM-receptor interaction);04974(Protein digestion and absorption);05165(Human papillomavirus infection)","NA","NA","collagen type IX alpha 2 chain [Source:HGNC Symbol;Acc:HGNC:2218]",{"v":0.376688,"d":"0.38"},{"v":0.47859,"d":"0.48"},{"v":0.147394,"d":"0.15"},0,0,0,"inf","inf",1,1,"up","no"]
[18722,0,"chr10","+",4826177,4848062,"ENST00000474119",10,1626,"ENSG00000165568","AKR1E2","GO:0004032(alditol:NADP+ 1-oxidoreductase activity);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0005794(Golgi apparatus);GO:0005829(cytosol);GO:0008106(alcohol dehydrogenase (NADP+) activity);GO:0016491(oxidoreductase activity);GO:0050571(1,5-anhydro-D-fructose reductase activity);GO:0055114(oxidation-reduction process)","NA","K13981","EC:1.1.1.263","aldo-keto reductase family 1 member E2 [Source:HGNC Symbol;Acc:HGNC:23437]",0,{"v":0.003152,"d":"0.00"},0,0,0,0,"inf","inf",1,1,"up","no"]
[200918,0,"chr9","+",137251261,137253483,"ENST00000388931",6,1207,"ENSG00000197768","STPG3","NA","NA","NA","NA","sperm-tail PG-rich repeat containing 3 [Source:HGNC Symbol;Acc:HGNC:37285]",{"v":0.12166,"d":"0.12"},{"v":0.0547,"d":"0.05"},{"v":0.346705,"d":"0.35"},{"v":0.097164,"d":"0.10"},{"v":0.175586,"d":"0.18"},{"v":0.383263,"d":"0.38"},{"v":0.797339381993954,"d":"0.80"},{"v":-0.326734166779307,"d":"-0.33"},1,1,"down","no"]
[157698,0,"chr5","+",14498516,14508333,"ENST00000508717",4,859,"ENSG00000038382","TRIO","GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005085(guanyl-nucleotide exchange factor activity);GO:0005089(Rho guanyl-nucleotide exchange factor activity);GO:0005515(protein binding);GO:0005524(ATP binding);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0006468(protein phosphorylation);GO:0007185(transmembrane receptor protein tyrosine phosphatase signaling pathway);GO:0007186(G protein-coupled receptor signaling pathway);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0016740(transferase activity);GO:0035023(regulation of Rho protein signal transduction);GO:0043065(positive regulation of apoptotic process);GO:0045599(negative regulation of fat cell differentiation);GO:0051056(regulation of small GTPase mediated signal transduction)","NA","K08810","EC:2.7.11.1","trio Rho guanine nucleotide exchange factor [Source:HGNC Symbol;Acc:HGNC:12303]",{"v":0.202185,"d":"0.20"},{"v":0.239139,"d":"0.24"},{"v":0.352773,"d":"0.35"},0,{"v":0.287596,"d":"0.29"},0,{"v":2.76115453622443,"d":"2.76"},{"v":1.46527163490371,"d":"1.47"},1,1,"up","no"]
[59916,0,"chr14","+",96256210,96268967,"ENST00000553356",5,1526,"ENSG00000100739","BDKRB1","GO:0001933(negative regulation of protein phosphorylation);GO:0002687(positive regulation of leukocyte migration);GO:0004930(G protein-coupled receptor activity);GO:0004947(bradykinin receptor activity);GO:0005515(protein binding);GO:0005783(endoplasmic reticulum);GO:0005886(plasma membrane);GO:0005887(integral component of plasma membrane);GO:0006954(inflammatory response);GO:0007165(signal transduction);GO:0007186(G protein-coupled receptor signaling pathway);GO:0007204(positive regulation of cytosolic calcium ion concentration);GO:0007205(protein kinase C-activating G protein-coupled receptor signaling pathway);GO:0009612(response to mechanical stimulus);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016477(cell migration);GO:0019233(sensory perception of pain);GO:0030308(negative regulation of cell growth);GO:0032496(response to lipopolysaccharide);GO:0042277(peptide binding);GO:0043005(neuron projection);GO:0045776(negative regulation of blood pressure);GO:0051281(positive regulation of release of sequestered calcium ion into cytosol)","04020(Calcium signaling pathway);04080(Neuroactive ligand-receptor interaction);04610(Complement and coagulation cascades);04750(Inflammatory mediator regulation of TRP channels);04810(Regulation of actin cytoskeleton);05200(Pathways in cancer)","NA","NA","bradykinin receptor B1 [Source:HGNC Symbol;Acc:HGNC:1029]",0,0,0,0,{"v":0.009041,"d":"0.01"},0,"-inf","-inf",1,1,"down","no"]
[163111,0,"chr5","+",138338266,138347080,"ENST00000513056",5,923,"ENSG00000120709","FAM53C","GO:0005515(protein binding)","NA","NA","NA","family with sequence similarity 53 member C [Source:HGNC Symbol;Acc:HGNC:1336]",0,0,{"v":0.310431,"d":"0.31"},0,0,0,"inf","inf",1,1,"up","no"]
[197205,0,"chr9","+",89332588,89338510,"ENST00000440898",3,547,"ENSG00000187742","SECISBP2","GO:0001514(selenocysteine incorporation);GO:0003723(RNA binding);GO:0003730(mRNA 3'-UTR binding);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005739(mitochondrion);GO:0006412(translation);GO:0021756(striatum development);GO:0035368(selenocysteine insertion sequence binding);GO:0043021(ribonucleoprotein complex binding);GO:0048666(neuron development);GO:1990904(ribonucleoprotein complex);GO:2000623(negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)","NA","K19539","NA","SECIS binding protein 2 [Source:HGNC Symbol;Acc:HGNC:30972]",{"v":0.161046,"d":"0.16"},{"v":0.205389,"d":"0.21"},{"v":0.198138,"d":"0.20"},{"v":0.180431,"d":"0.18"},{"v":0.307548,"d":"0.31"},{"v":0.419009,"d":"0.42"},{"v":0.622470198062157,"d":"0.62"},{"v":-0.68392332780649,"d":"-0.68"},1,1,"down","no"]
[41925,0,"chr12","+",45852295,45908040,"ENST00000457135",8,4356,"ENSG00000189079","ARID2","GO:0000981(DNA-binding transcription factor activity, RNA polymerase II-specific);GO:0003007(heart morphogenesis);GO:0003676(nucleic acid binding);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005886(plasma membrane);GO:0006325(chromatin organization);GO:0006337(nucleosome disassembly);GO:0006355(regulation of transcription, DNA-templated);GO:0006357(regulation of transcription by RNA polymerase II);GO:0008285(negative regulation of cell population proliferation);GO:0030336(negative regulation of cell migration);GO:0042592(homeostatic process);GO:0046872(metal ion binding);GO:0048568(embryonic organ development);GO:0060038(cardiac muscle cell proliferation);GO:0060982(coronary artery morphogenesis);GO:0072358(cardiovascular system development)","05225(Hepatocellular carcinoma)","K11765","NA","AT-rich interaction domain 2 [Source:HGNC Symbol;Acc:HGNC:18037]",{"v":0.002157,"d":"0.00"},0,0,0,{"v":0.000802,"d":"0.00"},{"v":0.002057,"d":"0.00"},{"v":0.754459601259182,"d":"0.75"},{"v":-0.406484443470644,"d":"-0.41"},1,1,"down","no"]
[19370,0,"chr10","-",14819888,14836290,"ENST00000466269",4,581,"ENSG00000185267","CDNF","GO:0005576(extracellular region);GO:0005615(extracellular space);GO:0005783(endoplasmic reticulum);GO:0008083(growth factor activity);GO:0010469(regulation of signaling receptor activity);GO:0031175(neuron projection development);GO:0071542(dopaminergic neuron differentiation)","NA","NA","NA","cerebral dopamine neurotrophic factor [Source:HGNC Symbol;Acc:HGNC:24913]",0,0,0,{"v":0.159226,"d":"0.16"},0,0,"-inf","-inf",1,1,"down","no"]
[8263,0,"chr1","-",92262865,92286592,"ENST00000463560",9,734,"ENSG00000174842","GLMN","GO:0001570(vasculogenesis);GO:0001843(neural tube closure);GO:0005171(hepatocyte growth factor receptor binding);GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0031397(negative regulation of protein ubiquitination);GO:0031461(cullin-RING ubiquitin ligase complex);GO:0031462(Cul2-RING ubiquitin ligase complex);GO:0031463(Cul3-RING ubiquitin ligase complex);GO:0031464(Cul4A-RING E3 ubiquitin ligase complex);GO:0031625(ubiquitin protein ligase binding);GO:0032434(regulation of proteasomal ubiquitin-dependent protein catabolic process);GO:0040029(regulation of gene expression, epigenetic);GO:0042130(negative regulation of T cell proliferation);GO:0042327(positive regulation of phosphorylation);GO:0042692(muscle cell differentiation);GO:0045086(positive regulation of interleukin-2 biosynthetic process);GO:0050715(positive regulation of cytokine secretion);GO:0055105(ubiquitin-protein transferase inhibitor activity);GO:0072359(circulatory system development)","NA","NA","NA","glomulin, FKBP associated protein [Source:HGNC Symbol;Acc:HGNC:14373]",{"v":0.005543,"d":"0.01"},{"v":0.000634,"d":"0.00"},{"v":0.027062,"d":"0.03"},{"v":0.006408,"d":"0.01"},{"v":0.116277,"d":"0.12"},{"v":0.018781,"d":"0.02"},{"v":0.234961050711832,"d":"0.23"},{"v":-2.089506472574,"d":"-2.09"},1,1,"down","no"]
[87620,0,"chr17","-",50362967,50365232,"ENST00000624336",1,2266,"ENSG00000279792","AC015909","NA","NA","NA","NA","TEC",{"v":0.069589,"d":"0.07"},{"v":0.038636,"d":"0.04"},{"v":0.043761,"d":"0.04"},{"v":0.136737,"d":"0.14"},{"v":0.045543,"d":"0.05"},{"v":0.058705,"d":"0.06"},{"v":0.630686557254601,"d":"0.63"},{"v":-0.66500491162092,"d":"-0.67"},1,1,"down","no"]
[49367,0,"chr12","-",123194509,123202838,"ENST00000606326",4,485,"ENSG00000051825","MPHOSPH9","GO:0000139(Golgi membrane);GO:0005737(cytoplasm);GO:0005794(Golgi apparatus);GO:0005814(centriole);GO:0005856(cytoskeleton);GO:0016020(membrane)","NA","K16775","NA","M-phase phosphoprotein 9 [Source:HGNC Symbol;Acc:HGNC:7215]",0,0,0,{"v":0.167664,"d":"0.17"},0,{"v":0.106186,"d":"0.11"},"-inf","-inf",1,1,"down","no"]
[75893,0,"chr16","-",65004673,65122365,"ENST00000564317",3,566,"ENSG00000140937","CDH11","GO:0000902(cell morphogenesis);GO:0001501(skeletal system development);GO:0001503(ossification);GO:0005509(calcium ion binding);GO:0005737(cytoplasm);GO:0005886(plasma membrane);GO:0005913(cell-cell adherens junction);GO:0007043(cell-cell junction assembly);GO:0007155(cell adhesion);GO:0007156(homophilic cell adhesion via plasma membrane adhesion molecules);GO:0008092(cytoskeletal protein binding);GO:0009986(cell surface);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016339(calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules);GO:0016342(catenin complex);GO:0021957(corticospinal tract morphogenesis);GO:0034332(adherens junction organization);GO:0042803(protein homodimerization activity);GO:0044331(cell-cell adhesion mediated by cadherin);GO:0045202(synapse);GO:0045296(cadherin binding);GO:0046872(metal ion binding);GO:0050804(modulation of chemical synaptic transmission);GO:0070062(extracellular exosome);GO:0098609(cell-cell adhesion);GO:0098685(Schaffer collateral - CA1 synapse);GO:0098978(glutamatergic synapse)","NA","NA","NA","cadherin 11 [Source:HGNC Symbol;Acc:HGNC:1750]",{"v":0.825311,"d":"0.83"},{"v":0.648647,"d":"0.65"},{"v":0.077874,"d":"0.08"},{"v":1.139133,"d":"1.14"},{"v":0.041189,"d":"0.04"},{"v":0.05403,"d":"0.05"},{"v":1.25720377979701,"d":"1.26"},{"v":0.330218514734353,"d":"0.33"},1,1,"up","no"]
[26020,0,"chr11","-",904701,914801,"ENST00000525840",2,438,"ENSG00000177830","CHID1","GO:0002376(immune system process);GO:0002576(platelet degranulation);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0005615(extracellular space);GO:0005634(nucleus);GO:0005764(lysosome);GO:0005770(late endosome);GO:0005802(trans-Golgi network);GO:0005975(carbohydrate metabolic process);GO:0008061(chitin binding);GO:0016020(membrane);GO:0043202(lysosomal lumen);GO:0045087(innate immune response);GO:0070062(extracellular exosome);GO:0070492(oligosaccharide binding);GO:1900016(negative regulation of cytokine production involved in inflammatory response)","NA","K17525","NA","chitinase domain containing 1 [Source:HGNC Symbol;Acc:HGNC:28474]",0,0,0,0,0,0,1,0,1,1,"no","no"]
[88802,0,"chr17","-",63434261,63436706,"ENST00000581163",5,869,"ENSG00000008283","CYB561","GO:0000293(ferric-chelate reductase activity);GO:0005515(protein binding);GO:0005765(lysosomal membrane);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016491(oxidoreductase activity);GO:0022900(electron transport chain);GO:0046872(metal ion binding);GO:0055114(oxidation-reduction process)","NA","K08360","EC:7.2.1.3","cytochrome b561 [Source:HGNC Symbol;Acc:HGNC:2571]",{"v":0.020219,"d":"0.02"},0,0,0,{"v":0.012066,"d":"0.01"},{"v":0.023885,"d":"0.02"},{"v":0.562404383744541,"d":"0.56"},{"v":-0.830320255132209,"d":"-0.83"},1,1,"down","no"]
[114475,0,"chr2","-",85398720,85410352,"ENST00000459793",6,943,"ENSG00000042493","CAPG","GO:0001726(ruffle);GO:0003779(actin binding);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005730(nucleolus);GO:0005737(cytoplasm);GO:0005814(centriole);GO:0008290(F-actin capping protein complex);GO:0019904(protein domain specific binding);GO:0030027(lamellipodium);GO:0042470(melanosome);GO:0042995(cell projection);GO:0044877(protein-containing complex binding);GO:0045296(cadherin binding);GO:0051015(actin filament binding);GO:0051016(barbed-end actin filament capping);GO:0051693(actin filament capping);GO:0065003(protein-containing complex assembly);GO:0070062(extracellular exosome);GO:0072686(mitotic spindle);GO:0090543(Flemming body)","NA","NA","NA","capping actin protein, gelsolin like [Source:HGNC Symbol;Acc:HGNC:1474]",{"v":1.01883,"d":"1.02"},{"v":0.115894,"d":"0.12"},0,0,0,{"v":0.560361,"d":"0.56"},{"v":2.02498746343875,"d":"2.02"},{"v":1.0179129763969,"d":"1.02"},1,1,"up","no"]
[62161,0,"chr15","+",30484544,30507623,"ENST00000564861",3,618,"ENSG00000215302","AC127502","NA","NA","NA","NA","WAS protein homolog associated with actin, golgi membranes and microtubules (WHAMM) pseudogene",{"v":0.229185,"d":"0.23"},0,{"v":0.693531,"d":"0.69"},0,{"v":0.358602,"d":"0.36"},{"v":0.222562,"d":"0.22"},{"v":1.5877032988967,"d":"1.59"},{"v":0.666941334896746,"d":"0.67"},1,1,"up","no"]
[60929,0,"chr14","+",104049418,104052665,"ENST00000462273",2,948,"ENSG00000156414","TDRD9","GO:0000166(nucleotide binding);GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0004386(helicase activity);GO:0005524(ATP binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0007140(male meiotic nuclear division);GO:0007141(male meiosis I);GO:0007275(multicellular organism development);GO:0007283(spermatogenesis);GO:0009566(fertilization);GO:0010529(negative regulation of transposition);GO:0016787(hydrolase activity);GO:0016887(ATPase activity);GO:0030154(cell differentiation);GO:0031047(gene silencing by RNA);GO:0034459(ATP-dependent 3'-5' RNA helicase activity);GO:0034587(piRNA metabolic process);GO:0043046(DNA methylation involved in gamete generation);GO:0051321(meiotic cell cycle);GO:0071547(piP-body)","NA","K18408","EC:3.6.4.13","tudor domain containing 9 [Source:HGNC Symbol;Acc:HGNC:20122]",{"v":0.074542,"d":"0.07"},0,0,{"v":0.250128,"d":"0.25"},{"v":0.229907,"d":"0.23"},{"v":0.077317,"d":"0.08"},{"v":0.133743128220586,"d":"0.13"},{"v":-2.90246332776063,"d":"-2.90"},1,1,"down","no"]
[127297,0,"chr20","-",45435272,45448325,"ENST00000617473",2,1794,"ENSG00000277022","AL031663","NA","NA","NA","NA","novel transcript",0,0,0,0,0,0,1,0,1,1,"no","no"]
[78798,0,"chr16","-",88811174,88811920,"ENST00000564858",2,584,"ENSG00000198931","APRT","GO:0002055(adenine binding);GO:0003999(adenine phosphoribosyltransferase activity);GO:0005576(extracellular region);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0006166(purine ribonucleoside salvage);GO:0006168(adenine salvage);GO:0007595(lactation);GO:0007625(grooming behavior);GO:0009116(nucleoside metabolic process);GO:0016208(AMP binding);GO:0016740(transferase activity);GO:0016757(transferase activity, transferring glycosyl groups);GO:0032869(cellular response to insulin stimulus);GO:0034774(secretory granule lumen);GO:0043101(purine-containing compound salvage);GO:0043312(neutrophil degranulation);GO:0044209(AMP salvage);GO:0046083(adenine metabolic process);GO:0070062(extracellular exosome)","00230(Purine metabolism)","NA","NA","adenine phosphoribosyltransferase [Source:HGNC Symbol;Acc:HGNC:626]",{"v":0.479625,"d":"0.48"},{"v":0.795407,"d":"0.80"},{"v":0.85675,"d":"0.86"},{"v":0.839892,"d":"0.84"},{"v":0.639544,"d":"0.64"},{"v":0.761342,"d":"0.76"},{"v":0.951357965849361,"d":"0.95"},{"v":-0.071939811231253,"d":"-0.07"},1,1,"down","no"]
[116310,0,"chr2","-",111429318,111523376,"ENST00000643766",5,963,"ENSG00000172965","MIR4435-2HG","NA","NA","NA","NA","MIR4435-2 host gene [Source:HGNC Symbol;Acc:HGNC:35163]",0,{"v":0.030466,"d":"0.03"},{"v":0.179681,"d":"0.18"},{"v":0.171422,"d":"0.17"},{"v":0.076841,"d":"0.08"},0,{"v":0.846469268477381,"d":"0.85"},{"v":-0.240470403636022,"d":"-0.24"},1,1,"down","no"]
[108729,0,"chr19","+",57351307,57359898,"ENST00000391705",4,4313,"ENSG00000131845","ZNF304","GO:0000981(DNA-binding transcription factor activity, RNA polymerase II-specific);GO:0001525(angiogenesis);GO:0003676(nucleic acid binding);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0005622(intracellular);GO:0005634(nucleus);GO:0006325(chromatin organization);GO:0006355(regulation of transcription, DNA-templated);GO:0007229(integrin-mediated signaling pathway);GO:0007265(Ras protein signal transduction);GO:0030335(positive regulation of cell migration);GO:0035562(negative regulation of chromatin binding);GO:0045766(positive regulation of angiogenesis);GO:0045944(positive regulation of transcription by RNA polymerase II);GO:0046872(metal ion binding);GO:0050679(positive regulation of epithelial cell proliferation);GO:0090309(positive regulation of methylation-dependent chromatin silencing);GO:1900114(positive regulation of histone H3-K9 trimethylation);GO:1902466(positive regulation of histone H3-K27 trimethylation);GO:1990841(promoter-specific chromatin binding);GO:2000811(negative regulation of anoikis)","05168(Herpes simplex virus 1 infection)","K09228","NA","zinc finger protein 304 [Source:HGNC Symbol;Acc:HGNC:13505]",0,0,0,0,0,0,1,0,1,1,"no","no"]
[118798,0,"chr2","-",165996053,166000063,"ENST00000473295",3,544,"ENSG00000144285","SCN1A","GO:0001508(action potential);GO:0001518(voltage-gated sodium channel complex);GO:0005216(ion channel activity);GO:0005244(voltage-gated ion channel activity);GO:0005248(voltage-gated sodium channel activity);GO:0005272(sodium channel activity);GO:0005654(nucleoplasm);GO:0005886(plasma membrane);GO:0006811(ion transport);GO:0006814(sodium ion transport);GO:0007628(adult walking behavior);GO:0014704(intercalated disc);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016604(nuclear body);GO:0019227(neuronal action potential propagation);GO:0019228(neuronal action potential);GO:0030018(Z disc);GO:0030315(T-tubule);GO:0030424(axon);GO:0033268(node of Ranvier);GO:0034220(ion transmembrane transport);GO:0034706(sodium channel complex);GO:0034765(regulation of ion transmembrane transport);GO:0035725(sodium ion transmembrane transport);GO:0042391(regulation of membrane potential);GO:0043025(neuronal cell body);GO:0043194(axon initial segment);GO:0050884(neuromuscular process controlling posture);GO:0050966(detection of mechanical stimulus involved in sensory perception of pain);GO:0055085(transmembrane transport);GO:0086002(cardiac muscle cell action potential involved in contraction);GO:0086010(membrane depolarization during action potential)","04728(Dopaminergic synapse)","K04833","NA","sodium voltage-gated channel alpha subunit 1 [Source:HGNC Symbol;Acc:HGNC:10585]",0,0,{"v":0.05159,"d":"0.05"},0,0,0,"inf","inf",1,1,"up","no"]
[51496,0,"chr13","+",45341599,45360486,"ENST00000618947",3,520,"ENSG00000170919","TPT1-AS1","NA","NA","NA","NA","TPT1 antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:43686]",{"v":0.122295,"d":"0.12"},0,0,0,0,{"v":0.633232,"d":"0.63"},{"v":0.193128268944084,"d":"0.19"},{"v":-2.37236874219654,"d":"-2.37"},1,1,"down","no"]
[201769,0,"chrX","+",17656139,17687894,"ENST00000648929",2,379,"ENSG00000188158","NHS","GO:0002088(lens development in camera-type eye);GO:0005737(cytoplasm);GO:0005794(Golgi apparatus);GO:0005886(plasma membrane);GO:0005923(bicellular tight junction);GO:0005925(focal adhesion);GO:0016020(membrane);GO:0016324(apical plasma membrane);GO:0016604(nuclear body);GO:0030027(lamellipodium);GO:0030054(cell junction);GO:0030154(cell differentiation);GO:0042995(cell projection)","NA","NA","NA","NHS actin remodeling regulator [Source:HGNC Symbol;Acc:HGNC:7820]",0,0,0,0,{"v":0.011649,"d":"0.01"},0,"-inf","-inf",1,1,"down","no"]
[73661,0,"chr16","-",30093745,30095588,"ENST00000568681",2,1739,"ENSG00000090238","YPEL3","GO:0005634(nucleus);GO:0005730(nucleolus);GO:0046872(metal ion binding);GO:2000774(positive regulation of cellular senescence)","NA","NA","NA","yippee like 3 [Source:HGNC Symbol;Acc:HGNC:18327]",{"v":0.123939,"d":"0.12"},{"v":0.05098,"d":"0.05"},{"v":0.029121,"d":"0.03"},{"v":0.059523,"d":"0.06"},{"v":0.079557,"d":"0.08"},{"v":0.112554,"d":"0.11"},{"v":0.810860217617651,"d":"0.81"},{"v":-0.302474861987314,"d":"-0.30"},1,1,"down","no"]
[96730,0,"chr19","+",1508375,1508963,"ENST00000590252",2,457,"ENSG00000267092","AC027307","NA","NA","NA","NA","novel transcript, antisense to ADAMTSL5",0,{"v":0.146837,"d":"0.15"},{"v":0.144316,"d":"0.14"},{"v":0.023394,"d":"0.02"},{"v":0.092319,"d":"0.09"},{"v":0.069167,"d":"0.07"},{"v":1.57482150584163,"d":"1.57"},{"v":0.655188319260097,"d":"0.66"},1,1,"up","no"]
[181626,0,"chr7","+",99374729,99388117,"ENST00000418347",6,563,"ENSG00000130429","ARPC1B","GO:0003779(actin binding);GO:0005200(structural constituent of cytoskeleton);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005856(cytoskeleton);GO:0005885(Arp2/3 protein complex);GO:0005925(focal adhesion);GO:0015629(actin cytoskeleton);GO:0030833(regulation of actin filament polymerization);GO:0032355(response to estradiol);GO:0034314(Arp2/3 complex-mediated actin nucleation);GO:0036284(tubulobulbar complex);GO:0038096(Fc-gamma receptor signaling pathway involved in phagocytosis);GO:0043627(response to estrogen);GO:0044877(protein-containing complex binding);GO:0048013(ephrin receptor signaling pathway);GO:0051015(actin filament binding);GO:0070062(extracellular exosome)","04144(Endocytosis);04666(Fc gamma R-mediated phagocytosis);04810(Regulation of actin cytoskeleton);05100(Bacterial invasion of epithelial cells);05130(Pathogenic Escherichia coli infection);05131(Shigellosis);05132(Salmonella infection)","K05757","NA","actin related protein 2/3 complex subunit 1B [Source:HGNC Symbol;Acc:HGNC:704]",0,0,0,0,0,{"v":7e-6,"d":"0.00"},"-inf","-inf",1,1,"down","no"]
[59836,0,"chr14","-",95191527,95196584,"ENST00000557696",4,746,"ENSG00000165959","CLMN","GO:0003779(actin binding);GO:0005515(protein binding);GO:0005640(nuclear outer membrane);GO:0005737(cytoplasm);GO:0007097(nuclear migration);GO:0008285(negative regulation of cell population proliferation);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0031175(neuron projection development);GO:0034993(meiotic nuclear membrane microtubule tethering complex);GO:0051015(actin filament binding);GO:0051647(nucleus localization);GO:0090286(cytoskeletal anchoring at nuclear membrane)","NA","NA","NA","calmin [Source:HGNC Symbol;Acc:HGNC:19972]",0,0,0,0,0,0,1,0,1,1,"no","no"]
[83270,0,"chr17","+",28357652,28358468,"ENST00000579762",2,385,"ENSG00000244045","TMEM199","GO:0005515(protein binding);GO:0005764(lysosome);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0006879(cellular iron ion homeostasis);GO:0007042(lysosomal lumen acidification);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016471(vacuolar proton-transporting V-type ATPase complex);GO:0030663(COPI-coated vesicle membrane);GO:0031410(cytoplasmic vesicle);GO:0033116(endoplasmic reticulum-Golgi intermediate compartment membrane);GO:0036295(cellular response to increased oxygen levels);GO:0070072(vacuolar proton-transporting V-type ATPase complex assembly);GO:1905146(lysosomal protein catabolic process)","NA","NA","NA","transmembrane protein 199 [Source:HGNC Symbol;Acc:HGNC:18085]",0,0,{"v":0.460203,"d":"0.46"},0,0,0,"inf","inf",1,1,"up","no"]
[57504,0,"chr14","+",64440221,64445138,"ENST00000556771",5,813,"ENSG00000100714","MTHFD1","GO:0000105(histidine biosynthetic process);GO:0000166(nucleotide binding);GO:0001780(neutrophil homeostasis);GO:0001843(neural tube closure);GO:0003824(catalytic activity);GO:0004329(formate-tetrahydrofolate ligase activity);GO:0004477(methenyltetrahydrofolate cyclohydrolase activity);GO:0004486(methylenetetrahydrofolate dehydrogenase [NAD(P)+] activity);GO:0004487(methylenetetrahydrofolate dehydrogenase (NAD+) activity);GO:0004488(methylenetetrahydrofolate dehydrogenase (NADP+) activity);GO:0005515(protein binding);GO:0005524(ATP binding);GO:0005737(cytoplasm);GO:0005739(mitochondrion);GO:0005829(cytosol);GO:0006164(purine nucleotide biosynthetic process);GO:0006555(methionine metabolic process);GO:0006730(one-carbon metabolic process);GO:0007507(heart development);GO:0008152(metabolic process);GO:0008652(cellular amino acid biosynthetic process);GO:0009069(serine family amino acid metabolic process);GO:0009070(serine family amino acid biosynthetic process);GO:0009086(methionine biosynthetic process);GO:0009113(purine nucleobase biosynthetic process);GO:0009257(10-formyltetrahydrofolate biosynthetic process);GO:0016020(membrane);GO:0016491(oxidoreductase activity);GO:0016787(hydrolase activity);GO:0016874(ligase activity);GO:0019346(transsulfuration);GO:0035999(tetrahydrofolate interconversion);GO:0046655(folic acid metabolic process);GO:0048702(embryonic neurocranium morphogenesis);GO:0048703(embryonic viscerocranium morphogenesis);GO:0055114(oxidation-reduction process);GO:0061053(somite development);GO:0070062(extracellular exosome)","00670(One carbon pool by folate)","K00288","3.5.4.9;6.3.4.3;EC:1.5.1.5","methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1 [Source:HGNC Symbol;Acc:HGNC:7432]",{"v":0.460929,"d":"0.46"},{"v":0.538377,"d":"0.54"},{"v":0.516627,"d":"0.52"},{"v":0.42467,"d":"0.42"},{"v":0.128266,"d":"0.13"},{"v":0.982042,"d":"0.98"},{"v":0.987592656051096,"d":"0.99"},{"v":-0.0180119865537487,"d":"-0.02"},1,1,"down","no"]
[140701,0,"chr3","+",52470556,52472373,"ENST00000488157",5,590,"ENSG00000010322","NISCH","GO:0005178(integrin binding);GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0005768(endosome);GO:0005769(early endosome);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0006006(glucose metabolic process);GO:0006915(apoptotic process);GO:0008217(regulation of blood pressure);GO:0016020(membrane);GO:0016601(Rac protein signal transduction);GO:0019901(protein kinase binding);GO:0030036(actin cytoskeleton organization);GO:0030336(negative regulation of cell migration);GO:0032228(regulation of synaptic transmission, GABAergic);GO:0035091(phosphatidylinositol binding);GO:0042802(identical protein binding);GO:0048243(norepinephrine secretion);GO:0055037(recycling endosome)","NA","NA","NA","nischarin [Source:HGNC Symbol;Acc:HGNC:18006]",{"v":0.058553,"d":"0.06"},0,0,0,0,{"v":0.05117,"d":"0.05"},{"v":1.14428376001563,"d":"1.14"},{"v":0.194444856665379,"d":"0.19"},1,1,"up","no"]
[113487,0,"chr2","-",70050811,70060106,"ENST00000602091",2,959,"ENSG00000179818","PCBP1-AS1","NA","NA","NA","NA","PCBP1 antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:42948]",{"v":0.263513,"d":"0.26"},{"v":0.280242,"d":"0.28"},{"v":0.191865,"d":"0.19"},0,{"v":0.030739,"d":"0.03"},{"v":0.013986,"d":"0.01"},{"v":16.4476243711571,"d":"16.45"},{"v":4.03980731681432,"d":"4.04"},1,1,"up","no"]
[91475,0,"chr17","+",80994581,80998670,"ENST00000572778",6,737,"ENSG00000176108","CHMP6","GO:0000815(ESCRT III complex);GO:0005515(protein binding);GO:0005768(endosome);GO:0005829(cytosol);GO:0006997(nucleus organization);GO:0007034(vacuolar transport);GO:0007080(mitotic metaphase plate congression);GO:0007175(negative regulation of epidermal growth factor-activated receptor activity);GO:0010008(endosome membrane);GO:0012505(endomembrane system);GO:0015031(protein transport);GO:0016020(membrane);GO:0016197(endosomal transport);GO:0016236(macroautophagy);GO:0019058(viral life cycle);GO:0031902(late endosome membrane);GO:0036258(multivesicular body assembly);GO:0039702(viral budding via host ESCRT complex);GO:0042176(regulation of protein catabolic process);GO:0044877(protein-containing complex binding);GO:0047485(protein N-terminus binding);GO:0061952(midbody abscission);GO:0070062(extracellular exosome);GO:1904902(ESCRT III complex assembly)","04144(Endocytosis);04217(Necroptosis)","K12195","NA","charged multivesicular body protein 6 [Source:HGNC Symbol;Acc:HGNC:25675]",{"v":0.130688,"d":"0.13"},{"v":0.409276,"d":"0.41"},{"v":0.445071,"d":"0.45"},{"v":0.142357,"d":"0.14"},{"v":0.289553,"d":"0.29"},{"v":0.345644,"d":"0.35"},{"v":1.26683805883579,"d":"1.27"},{"v":0.34123211512862,"d":"0.34"},1,1,"up","no"]
[91542,0,"chr17","-",81199818,81204071,"ENST00000570482",5,613,"ENSG00000141577","CEP131","GO:0000086(G2/M transition of mitotic cell cycle);GO:0001669(acrosomal vesicle);GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0005813(centrosome);GO:0005815(microtubule organizing center);GO:0005829(cytosol);GO:0005856(cytoskeleton);GO:0005929(cilium);GO:0007049(cell cycle);GO:0007275(multicellular organism development);GO:0007283(spermatogenesis);GO:0008284(positive regulation of cell population proliferation);GO:0010389(regulation of G2/M transition of mitotic cell cycle);GO:0010824(regulation of centrosome duplication);GO:0015630(microtubule cytoskeleton);GO:0030030(cell projection organization);GO:0030154(cell differentiation);GO:0031410(cytoplasmic vesicle);GO:0034451(centriolar satellite);GO:0035735(intraciliary transport involved in cilium assembly);GO:0035869(ciliary transition zone);GO:0036064(ciliary basal body);GO:0042803(protein homodimerization activity);GO:0042995(cell projection);GO:0043231(intracellular membrane-bounded organelle);GO:0044877(protein-containing complex binding);GO:0045171(intercellular bridge);GO:0060271(cilium assembly);GO:0071539(protein localization to centrosome);GO:0090316(positive regulation of intracellular protein transport);GO:0097711(ciliary basal body-plasma membrane docking)","NA","K16540","NA","centrosomal protein 131 [Source:HGNC Symbol;Acc:HGNC:29511]",0,0,{"v":0.026961,"d":"0.03"},0,0,0,"inf","inf",1,1,"up","no"]
[100756,0,"chr19","+",17499870,17504601,"ENST00000598848",4,497,"ENSG00000130304","SLC27A1","GO:0000166(nucleotide binding);GO:0001579(medium-chain fatty acid transport);GO:0001676(long-chain fatty acid metabolic process);GO:0003824(catalytic activity);GO:0004467(long-chain fatty acid-CoA ligase activity);GO:0005324(long-chain fatty acid transporter activity);GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0005739(mitochondrion);GO:0005743(mitochondrial inner membrane);GO:0005783(endoplasmic reticulum);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0005887(integral component of plasma membrane);GO:0006629(lipid metabolic process);GO:0006631(fatty acid metabolic process);GO:0006646(phosphatidylethanolamine biosynthetic process);GO:0006654(phosphatidic acid biosynthetic process);GO:0006655(phosphatidylglycerol biosynthetic process);GO:0006656(phosphatidylcholine biosynthetic process);GO:0006659(phosphatidylserine biosynthetic process);GO:0006661(phosphatidylinositol biosynthetic process);GO:0006869(lipid transport);GO:0009409(response to cold);GO:0010867(positive regulation of triglyceride biosynthetic process);GO:0012505(endomembrane system);GO:0015245(fatty acid transmembrane transporter activity);GO:0015908(fatty acid transport);GO:0015909(long-chain fatty acid transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016874(ligase activity);GO:0019216(regulation of lipid metabolic process);GO:0031652(positive regulation of heat generation);GO:0031957(very long-chain fatty acid-CoA ligase activity);GO:0032049(cardiolipin biosynthetic process);GO:0032868(response to insulin);GO:0033211(adiponectin-activated signaling pathway);GO:0042803(protein homodimerization activity);GO:0044539(long-chain fatty acid import into cell);GO:0071072(negative regulation of phospholipid biosynthetic process);GO:0071902(positive regulation of protein serine/threonine kinase activity)","03320(PPAR signaling pathway);04931(Insulin resistance)","K08745","EC:6.2.1.-","solute carrier family 27 member 1 [Source:HGNC Symbol;Acc:HGNC:10995]",{"v":0.003595,"d":"0.00"},{"v":0.035841,"d":"0.04"},{"v":0.020391,"d":"0.02"},{"v":0.036138,"d":"0.04"},{"v":0.161702,"d":"0.16"},0,{"v":0.30240093004448,"d":"0.30"},{"v":-1.72546551826324,"d":"-1.73"},1,1,"down","no"]
[5785,0,"chr1","-",46195484,46198102,"ENST00000489985",5,1094,"ENSG00000085998","POMGNT1","GO:0000139(Golgi membrane);GO:0005515(protein binding);GO:0005794(Golgi apparatus);GO:0006486(protein glycosylation);GO:0006493(protein O-linked glycosylation);GO:0008375(acetylglucosaminyltransferase activity);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016266(O-glycan processing);GO:0016740(transferase activity);GO:0016757(transferase activity, transferring glycosyl groups);GO:0030145(manganese ion binding);GO:0030173(integral component of Golgi membrane);GO:0046872(metal ion binding);GO:0047223(beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase activity)","00515(Mannose type O-glycan biosynthesis)","K09666","EC:2.4.1.-","protein O-linked mannose N-acetylglucosaminyltransferase 1 (beta 1,2-) [Source:HGNC Symbol;Acc:HGNC:19139]",{"v":0.070156,"d":"0.07"},{"v":0.040227,"d":"0.04"},{"v":0.05161,"d":"0.05"},0,{"v":0.007238,"d":"0.01"},{"v":0.104048,"d":"0.10"},{"v":1.45564581348957,"d":"1.46"},{"v":0.541659362897117,"d":"0.54"},1,1,"up","no"]
[198354,0,"chr9","-",112033394,112036310,"ENST00000568421",1,2917,"ENSG00000259953","AL138756","NA","NA","NA","NA","novel transcript, overlapping SUSD1",{"v":0.139766,"d":"0.14"},{"v":0.128238,"d":"0.13"},{"v":0.225134,"d":"0.23"},{"v":0.20687,"d":"0.21"},{"v":0.259637,"d":"0.26"},{"v":0.147915,"d":"0.15"},{"v":0.802604724440206,"d":"0.80"},{"v":-0.31723844648638,"d":"-0.32"},1,1,"down","no"]
[193989,0,"chr8","+",144785298,144785588,"ENST00000462960",1,291,"ENSG00000244307","RN7SL395P","NA","NA","NA","NA","RNA, 7SL, cytoplasmic 395, pseudogene [Source:HGNC Symbol;Acc:HGNC:46411]",0,{"v":0.092776,"d":"0.09"},0,0,{"v":0.115054,"d":"0.12"},0,{"v":0.806369183166165,"d":"0.81"},{"v":-0.310487590155291,"d":"-0.31"},1,1,"down","no"]
[47539,0,"chr12","-",107734191,107761272,"ENST00000550376",12,2591,"ENSG00000110851","PRDM4","GO:0000977(RNA polymerase II regulatory region sequence-specific DNA binding);GO:0000978(RNA polymerase II proximal promoter sequence-specific DNA binding);GO:0000981(DNA-binding transcription factor activity, RNA polymerase II-specific);GO:0001228(DNA-binding transcription activator activity, RNA polymerase II-specific);GO:0003676(nucleic acid binding);GO:0003677(DNA binding);GO:0003700(DNA-binding transcription factor activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0006366(transcription by RNA polymerase II);GO:0007165(signal transduction);GO:0008168(methyltransferase activity);GO:0008270(zinc ion binding);GO:0008283(cell population proliferation);GO:0016740(transferase activity);GO:0031490(chromatin DNA binding);GO:0032259(methylation);GO:0035097(histone methyltransferase complex);GO:0043565(sequence-specific DNA binding);GO:0043985(histone H4-R3 methylation);GO:0045944(positive regulation of transcription by RNA polymerase II);GO:0046872(metal ion binding);GO:1990226(histone methyltransferase binding)","04722(Neurotrophin signaling pathway)","K12463","NA","PR/SET domain 4 [Source:HGNC Symbol;Acc:HGNC:9348]",{"v":0.045349,"d":"0.05"},{"v":0.172126,"d":"0.17"},{"v":0.021223,"d":"0.02"},{"v":0.055232,"d":"0.06"},{"v":0.050862,"d":"0.05"},{"v":0.075229,"d":"0.08"},{"v":1.31642428153075,"d":"1.32"},{"v":0.396624542423366,"d":"0.40"},1,1,"up","no"]
[65411,0,"chr15","-",65234460,65261007,"ENST00000559805",4,678,"ENSG00000138617","PARP16","GO:0003950(NAD+ ADP-ribosyltransferase activity);GO:0005515(protein binding);GO:0005635(nuclear envelope);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005829(cytosol);GO:0006471(protein ADP-ribosylation);GO:0006986(response to unfolded protein);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016740(transferase activity);GO:0016757(transferase activity, transferring glycosyl groups);GO:0019900(kinase binding);GO:0030968(endoplasmic reticulum unfolded protein response);GO:0034356(NAD biosynthesis via nicotinamide riboside salvage pathway);GO:0036498(IRE1-mediated unfolded protein response);GO:0043539(protein serine/threonine kinase activator activity);GO:0060548(negative regulation of cell death);GO:0070213(protein auto-ADP-ribosylation);GO:0071782(endoplasmic reticulum tubular network);GO:0071902(positive regulation of protein serine/threonine kinase activity);GO:0140289(protein mono-ADP-ribosylation);GO:1990404(protein ADP-ribosylase activity);GO:1990830(cellular response to leukemia inhibitory factor)","NA","K00774","EC:2.4.2.30","poly(ADP-ribose) polymerase family member 16 [Source:HGNC Symbol;Acc:HGNC:26040]",{"v":0.290089,"d":"0.29"},{"v":0.063318,"d":"0.06"},{"v":0.221394,"d":"0.22"},{"v":0.117543,"d":"0.12"},0,{"v":0.090051,"d":"0.09"},{"v":2.76887096929584,"d":"2.77"},{"v":1.46929782499616,"d":"1.47"},1,1,"up","no"]
[73262,0,"chr16","-",28878957,28879920,"ENST00000566956",2,530,"ENSG00000260442","ATP2A1-AS1","NA","NA","NA","NA","ATP2A1 antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:51370]",{"v":0.169131,"d":"0.17"},{"v":0.726348,"d":"0.73"},0,{"v":0.551828,"d":"0.55"},{"v":0.425037,"d":"0.43"},{"v":0.878471,"d":"0.88"},{"v":0.48265058188921,"d":"0.48"},{"v":-1.05094897664673,"d":"-1.05"},1,1,"down","no"]
[29317,0,"chr11","+",43335279,43339373,"ENST00000529334",3,346,"ENSG00000166181","API5","GO:0003723(RNA binding);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005681(spliceosomal complex);GO:0005737(cytoplasm);GO:0006915(apoptotic process);GO:0016020(membrane);GO:0016607(nuclear speck);GO:0017134(fibroblast growth factor binding);GO:0043066(negative regulation of apoptotic process);GO:2000270(negative regulation of fibroblast apoptotic process)","NA","NA","NA","apoptosis inhibitor 5 [Source:HGNC Symbol;Acc:HGNC:594]",{"v":0.273019,"d":"0.27"},{"v":0.510649,"d":"0.51"},{"v":0.137781,"d":"0.14"},{"v":0.378293,"d":"0.38"},{"v":0.056889,"d":"0.06"},{"v":0.262514,"d":"0.26"},{"v":1.32070271292941,"d":"1.32"},{"v":0.401305755872844,"d":"0.40"},1,1,"up","no"]
[17217,0,"chr1","-",228108235,228109295,"ENST00000495434",4,224,"ENSG00000162910","MRPL55","GO:0003735(structural constituent of ribosome);GO:0005739(mitochondrion);GO:0005743(mitochondrial inner membrane);GO:0005762(mitochondrial large ribosomal subunit);GO:0005840(ribosome);GO:0006412(translation);GO:0070125(mitochondrial translational elongation);GO:0070126(mitochondrial translational termination)","NA","K17436","NA","mitochondrial ribosomal protein L55 [Source:HGNC Symbol;Acc:HGNC:16686]",{"v":0.125942,"d":"0.13"},{"v":0.326639,"d":"0.33"},{"v":0.237719,"d":"0.24"},{"v":0.106923,"d":"0.11"},{"v":0.223812,"d":"0.22"},0,{"v":2.0871694861445,"d":"2.09"},{"v":1.06154775760941,"d":"1.06"},1,1,"up","no"]
[113721,0,"chr2","+",71466699,71686763,"ENST00000410020",56,6775,"ENSG00000135636","DYSF","GO:0001525(angiogenesis);GO:0001778(plasma membrane repair);GO:0001938(positive regulation of endothelial cell proliferation);GO:0002280(monocyte activation involved in immune response);GO:0002281(macrophage activation involved in immune response);GO:0005509(calcium ion binding);GO:0005515(protein binding);GO:0005543(phospholipid binding);GO:0005544(calcium-dependent phospholipid binding);GO:0005634(nucleus);GO:0005768(endosome);GO:0005769(early endosome);GO:0005770(late endosome);GO:0005794(Golgi apparatus);GO:0005815(microtubule organizing center);GO:0005874(microtubule);GO:0005886(plasma membrane);GO:0006071(glycerol metabolic process);GO:0006906(vesicle fusion);GO:0006936(muscle contraction);GO:0008017(microtubule binding);GO:0008289(lipid binding);GO:0010629(negative regulation of gene expression);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0019915(lipid storage);GO:0030027(lamellipodium);GO:0030139(endocytic vesicle);GO:0030315(T-tubule);GO:0030659(cytoplasmic vesicle membrane);GO:0031410(cytoplasmic vesicle);GO:0033292(T-tubule organization);GO:0042177(negative regulation of protein catabolic process);GO:0042383(sarcolemma);GO:0043014(alpha-tubulin binding);GO:0043403(skeletal muscle tissue regeneration);GO:0045444(fat cell differentiation);GO:0045785(positive regulation of cell adhesion);GO:0046872(metal ion binding);GO:0048747(muscle fiber development);GO:0050663(cytokine secretion);GO:0050765(negative regulation of phagocytosis);GO:0070062(extracellular exosome);GO:0071470(cellular response to osmotic stress);GO:0090023(positive regulation of neutrophil chemotaxis);GO:0090279(regulation of calcium ion import);GO:0098857(membrane microdomain);GO:1901842(negative regulation of high voltage-gated calcium channel activity);GO:1902915(negative regulation of protein polyubiquitination)","NA","K18261","NA","dysferlin [Source:HGNC Symbol;Acc:HGNC:3097]",0,0,0,{"v":0.179905,"d":"0.18"},0,0,"-inf","-inf",1,1,"down","no"]
[19912,0,"chr10","-",26931206,26934923,"ENST00000638416",2,868,"ENSG00000283709","FAM238C","NA","NA","NA","NA","family with sequence similarity 238 member C [Source:HGNC Symbol;Acc:HGNC:24672]",{"v":0.006766,"d":"0.01"},{"v":0.076252,"d":"0.08"},0,0,0,{"v":0.002141,"d":"0.00"},{"v":38.7753386268099,"d":"38.78"},{"v":5.27706747532568,"d":"5.28"},1,1,"up","no"]
[112494,0,"chr2","-",55288084,55328425,"ENST00000412148",16,2974,"ENSG00000115355","CCDC88A","GO:0001932(regulation of protein phosphorylation);GO:0003779(actin binding);GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0005783(endoplasmic reticulum);GO:0005794(Golgi apparatus);GO:0005813(centrosome);GO:0005814(centriole);GO:0005829(cytosol);GO:0005856(cytoskeleton);GO:0005886(plasma membrane);GO:0006260(DNA replication);GO:0006275(regulation of DNA replication);GO:0007399(nervous system development);GO:0008017(microtubule binding);GO:0010975(regulation of neuron projection development);GO:0016020(membrane);GO:0016477(cell migration);GO:0030027(lamellipodium);GO:0030030(cell projection organization);GO:0030032(lamellipodium assembly);GO:0030142(COPI-coated Golgi to ER transport vesicle);GO:0030705(cytoskeleton-dependent intracellular transport);GO:0031122(cytoplasmic microtubule organization);GO:0031252(cell leading edge);GO:0031410(cytoplasmic vesicle);GO:0031682(G-protein gamma-subunit binding);GO:0031929(TOR signaling);GO:0032148(activation of protein kinase B activity);GO:0032956(regulation of actin cytoskeleton organization);GO:0035091(phosphatidylinositol binding);GO:0036064(ciliary basal body);GO:0042127(regulation of cell population proliferation);GO:0042803(protein homodimerization activity);GO:0042995(cell projection);GO:0043422(protein kinase B binding);GO:0045724(positive regulation of cilium assembly);GO:0051959(dynein light intermediate chain binding);GO:0061024(membrane organization);GO:1903566(positive regulation of protein localization to cilium)","NA","NA","NA","coiled-coil domain containing 88A [Source:HGNC Symbol;Acc:HGNC:25523]",{"v":0.018668,"d":"0.02"},{"v":0.093479,"d":"0.09"},{"v":0.054249,"d":"0.05"},{"v":0.05672,"d":"0.06"},{"v":0.005676,"d":"0.01"},{"v":0.058927,"d":"0.06"},{"v":1.37151240902385,"d":"1.37"},{"v":0.455767675307719,"d":"0.46"},1,1,"up","no"]
[87376,0,"chr17","+",49210707,49223225,"ENST00000225941",8,1629,"ENSG00000108798","ABI3","GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0017124(SH3 domain binding);GO:0030027(lamellipodium);GO:0030334(regulation of cell migration);GO:0042802(identical protein binding)","NA","NA","NA","ABI family member 3 [Source:HGNC Symbol;Acc:HGNC:29859]",0,{"v":0.067539,"d":"0.07"},{"v":0.325264,"d":"0.33"},{"v":0.01401,"d":"0.01"},0,{"v":0.035582,"d":"0.04"},{"v":7.92069285368608,"d":"7.92"},{"v":2.98562663394848,"d":"2.99"},1,1,"up","no"]
[11120,0,"chr1","-",151176731,151190145,"ENST00000496809",6,913,"ENSG00000163159","VPS72","GO:0000122(negative regulation of transcription by RNA polymerase II);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0006325(chromatin organization);GO:0006338(chromatin remodeling);GO:0006355(regulation of transcription, DNA-templated);GO:0016607(nuclear speck);GO:0032991(protein-containing complex);GO:0035019(somatic stem cell population maintenance);GO:0042393(histone binding);GO:0043486(histone exchange)","NA","K11664","NA","vacuolar protein sorting 72 homolog [Source:HGNC Symbol;Acc:HGNC:11644]",0,0,0,{"v":2.445496,"d":"2.45"},0,0,"-inf","-inf",1,1,"down","no"]
[62079,0,"chr15","+",28919367,29054094,"ENST00000558804",4,535,"ENSG00000034053","APBA2","GO:0001540(amyloid-beta binding);GO:0001701(in utero embryonic development);GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0005886(plasma membrane);GO:0007268(chemical synaptic transmission);GO:0007399(nervous system development);GO:0007626(locomotory behavior);GO:0008021(synaptic vesicle);GO:0010468(regulation of gene expression);GO:0015031(protein transport);GO:0035264(multicellular organism growth);GO:0042802(identical protein binding);GO:0043197(dendritic spine);GO:0045202(synapse);GO:0098685(Schaffer collateral - CA1 synapse);GO:2000300(regulation of synaptic vesicle exocytosis)","NA","NA","NA","amyloid beta precursor protein binding family A member 2 [Source:HGNC Symbol;Acc:HGNC:579]",0,0,0,0,0,0,1,0,1,1,"no","no"]
[173846,0,"chr6","-",129578419,129596875,"ENST00000483367",4,460,"ENSG00000146376","ARHGAP18","GO:0005096(GTPase activator activity);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0007165(signal transduction);GO:0007264(small GTPase mediated signal transduction);GO:0008360(regulation of cell shape);GO:0016607(nuclear speck);GO:0030833(regulation of actin filament polymerization);GO:0032956(regulation of actin cytoskeleton organization);GO:0043547(positive regulation of GTPase activity);GO:0045296(cadherin binding);GO:0051056(regulation of small GTPase mediated signal transduction);GO:2000145(regulation of cell motility)","NA","K20639","NA","Rho GTPase activating protein 18 [Source:HGNC Symbol;Acc:HGNC:21035]",0,0,0,0,0,0,1,0,1,1,"no","no"]
[205021,0,"chrX","+",102125727,102140426,"ENST00000651085",4,1640,"ENSG00000184905","TCEAL2","GO:0005634(nucleus);GO:0050699(WW domain binding)","NA","NA","NA","transcription elongation factor A like 2 [Source:HGNC Symbol;Acc:HGNC:29818]",0,0,0,0,0,0,1,0,1,1,"no","no"]
[73014,0,"chr16","+",27698328,27755752,"ENST00000573850",8,3237,"ENSG00000047578","KIAA0556","GO:0005615(extracellular space);GO:0005737(cytoplasm);GO:0005856(cytoskeleton);GO:0042995(cell projection)","NA","K22858","NA","KIAA0556 [Source:HGNC Symbol;Acc:HGNC:29068]",0,0,{"v":0.027166,"d":"0.03"},{"v":0.018722,"d":"0.02"},{"v":0.036995,"d":"0.04"},{"v":0.037785,"d":"0.04"},{"v":0.290539239802357,"d":"0.29"},{"v":-1.78319506982833,"d":"-1.78"},1,1,"down","no"]
[12520,0,"chr1","-",156595667,156601462,"ENST00000463513",9,857,"ENSG00000160818","GPATCH4","GO:0002244(hematopoietic progenitor cell differentiation);GO:0003676(nucleic acid binding)","NA","NA","NA","G-patch domain containing 4 [Source:HGNC Symbol;Acc:HGNC:25982]",0,0,0,0,0,0,1,0,1,1,"no","no"]
[120513,0,"chr2","-",196847476,196926730,"ENST00000409475",20,2443,"ENSG00000197121","PGAP1","GO:0004518(nuclease activity);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0006505(GPI anchor metabolic process);GO:0006506(GPI anchor biosynthetic process);GO:0006888(endoplasmic reticulum to Golgi vesicle-mediated transport);GO:0007605(sensory perception of sound);GO:0009880(embryonic pattern specification);GO:0009948(anterior/posterior axis specification);GO:0015031(protein transport);GO:0015798(myo-inositol transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016255(attachment of GPI anchor to protein);GO:0016787(hydrolase activity);GO:0016788(hydrolase activity, acting on ester bonds);GO:0021871(forebrain regionalization);GO:0042578(phosphoric ester hydrolase activity);GO:0050185(phosphatidylinositol deacylase activity);GO:0060322(head development);GO:0090305(nucleic acid phosphodiester bond hydrolysis)","00563(Glycosylphosphatidylinositol (GPI)-anchor biosynthesis)","K05294","EC:3.-.-.-","post-GPI attachment to proteins 1 [Source:HGNC Symbol;Acc:HGNC:25712]",{"v":0.061105,"d":"0.06"},0,0,{"v":0.028959,"d":"0.03"},0,{"v":0.032248,"d":"0.03"},{"v":0.99833352394334,"d":"1.00"},{"v":-0.00240622225592503,"d":"-0.00"},1,1,"down","no"]
[139032,0,"chr3","-",44737661,44761511,"ENST00000484437",4,507,"ENSG00000163807","KIAA1143","GO:0005515(protein binding)","NA","NA","NA","KIAA1143 [Source:HGNC Symbol;Acc:HGNC:29198]",{"v":0.260612,"d":"0.26"},{"v":0.142123,"d":"0.14"},{"v":0.156754,"d":"0.16"},{"v":0.222157,"d":"0.22"},{"v":0.138425,"d":"0.14"},{"v":0.112239,"d":"0.11"},{"v":1.1832998111336,"d":"1.18"},{"v":0.242815653758407,"d":"0.24"},1,1,"up","no"]
[197565,0,"chr9","+",94921209,95080756,"ENST00000462125",10,961,"ENSG00000148120","C9orf3","GO:0002003(angiotensin maturation);GO:0004177(aminopeptidase activity);GO:0005730(nucleolus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0006508(proteolysis);GO:0008233(peptidase activity);GO:0008237(metallopeptidase activity);GO:0008270(zinc ion binding);GO:0016787(hydrolase activity);GO:0046872(metal ion binding);GO:0070006(metalloaminopeptidase activity)","NA","K09606","EC:3.4.11.-","chromosome 9 open reading frame 3 [Source:HGNC Symbol;Acc:HGNC:1361]",0,0,0,{"v":0.167251,"d":"0.17"},{"v":0.066456,"d":"0.07"},0,"-inf","-inf",1,1,"down","no"]
[1448,0,"chr1","+",10399498,10408140,"ENST00000465632",5,642,"ENSG00000142657","PGD","GO:0004616(phosphogluconate dehydrogenase (decarboxylating) activity);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0006098(pentose-phosphate shunt);GO:0009051(pentose-phosphate shunt, oxidative branch);GO:0016491(oxidoreductase activity);GO:0019322(pentose biosynthetic process);GO:0019521(D-gluconate metabolic process);GO:0050661(NADP binding);GO:0055114(oxidation-reduction process);GO:0070062(extracellular exosome)","00030(Pentose phosphate pathway);00480(Glutathione metabolism)","K00033","1.1.1.343;EC:1.1.1.44","phosphogluconate dehydrogenase [Source:HGNC Symbol;Acc:HGNC:8891]",{"v":0.492339,"d":"0.49"},{"v":1.063081,"d":"1.06"},{"v":0.918913,"d":"0.92"},{"v":0.193731,"d":"0.19"},{"v":0.86297,"d":"0.86"},{"v":0.074922,"d":"0.07"},{"v":2.18653473815926,"d":"2.19"},{"v":1.12864626914722,"d":"1.13"},1,1,"up","no"]
[146349,0,"chr3","-",169793428,169812664,"ENST00000446859",11,1718,"ENSG00000171757","LRRC34","GO:0003674(molecular_function);GO:0005515(protein binding);GO:0005575(cellular_component);GO:0005634(nucleus);GO:0005730(nucleolus);GO:0005737(cytoplasm);GO:0008150(biological_process);GO:0030154(cell differentiation)","NA","NA","NA","leucine rich repeat containing 34 [Source:HGNC Symbol;Acc:HGNC:28408]",{"v":0.302682,"d":"0.30"},{"v":0.144183,"d":"0.14"},{"v":0.183285,"d":"0.18"},{"v":0.26426,"d":"0.26"},{"v":0.129111,"d":"0.13"},0,{"v":1.60192286670853,"d":"1.60"},{"v":0.679804683017448,"d":"0.68"},1,1,"up","no"]
[207598,0,"chrX","+",155047057,155054892,"ENST00000471528",3,765,"ENSG00000165775","FUNDC2","GO:0000422(autophagy of mitochondrion);GO:0005634(nucleus);GO:0005739(mitochondrion);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0031307(integral component of mitochondrial outer membrane)","NA","NA","NA","FUN14 domain containing 2 [Source:HGNC Symbol;Acc:HGNC:24925]",{"v":0.0109,"d":"0.01"},{"v":0.161674,"d":"0.16"},{"v":0.06083,"d":"0.06"},0,{"v":0.079768,"d":"0.08"},0,{"v":2.92603550295858,"d":"2.93"},{"v":1.54894727447693,"d":"1.55"},1,1,"up","no"]
[163109,0,"chr5","+",138338015,138345245,"ENST00000505768",3,772,"ENSG00000120709","FAM53C","GO:0005515(protein binding)","NA","NA","NA","family with sequence similarity 53 member C [Source:HGNC Symbol;Acc:HGNC:1336]",{"v":0.246699,"d":"0.25"},{"v":0.068154,"d":"0.07"},{"v":0.165164,"d":"0.17"},{"v":0.158182,"d":"0.16"},{"v":0.034039,"d":"0.03"},{"v":0.340633,"d":"0.34"},{"v":0.900841506303791,"d":"0.90"},{"v":-0.150654793713541,"d":"-0.15"},1,1,"down","no"]
[8633,0,"chr1","+",99850975,99924020,"ENST00000361302",34,7179,"ENSG00000162688","AGL","GO:0003824(catalytic activity);GO:0004133(glycogen debranching enzyme activity);GO:0004134(4-alpha-glucanotransferase activity);GO:0004135(amylo-alpha-1,6-glucosidase activity);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005977(glycogen metabolic process);GO:0005978(glycogen biosynthetic process);GO:0005980(glycogen catabolic process);GO:0007584(response to nutrient);GO:0008152(metabolic process);GO:0009725(response to hormone);GO:0016234(inclusion body);GO:0016529(sarcoplasmic reticulum);GO:0016740(transferase activity);GO:0016757(transferase activity, transferring glycosyl groups);GO:0016787(hydrolase activity);GO:0016798(hydrolase activity, acting on glycosyl bonds);GO:0030246(carbohydrate binding);GO:0030247(polysaccharide binding);GO:0031593(polyubiquitin modification-dependent protein binding);GO:0034774(secretory granule lumen);GO:0043033(isoamylase complex);GO:0043312(neutrophil degranulation);GO:0051384(response to glucocorticoid);GO:0102500(beta-maltose 4-alpha-glucanotransferase activity);GO:1904813(ficolin-1-rich granule lumen)","00500(Starch and sucrose metabolism)","NA","NA","amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase [Source:HGNC Symbol;Acc:HGNC:321]",0,0,0,0,0,{"v":0.029617,"d":"0.03"},"-inf","-inf",1,1,"down","no"]
[60377,0,"chr14","+",100987046,100987117,"ENST00000363543",1,72,"ENSG00000200413","SNORD114-26","NA","NA","NA","NA","small nucleolar RNA, C/D box 114-26 [Source:HGNC Symbol;Acc:HGNC:33014]",0,0,0,0,{"v":0.048545,"d":"0.05"},0,"-inf","-inf",1,1,"down","no"]
[153477,0,"chr4","-",99067256,99068125,"ENST00000609071",1,870,"ENSG00000272777","AC019131","NA","NA","NA","NA","novel transcript",{"v":0.276412,"d":"0.28"},{"v":0.132826,"d":"0.13"},{"v":0.420973,"d":"0.42"},{"v":0.224519,"d":"0.22"},{"v":0.341699,"d":"0.34"},{"v":0.650832,"d":"0.65"},{"v":0.682150281418183,"d":"0.68"},{"v":-0.551838487056159,"d":"-0.55"},1,1,"down","no"]
[135988,0,"chr22","+",50508259,50518058,"ENST00000418794",7,640,"ENSG00000025770","NCAPH2","GO:0000793(condensed chromosome);GO:0000796(condensin complex);GO:0003682(chromatin binding);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005694(chromosome);GO:0007076(mitotic chromosome condensation);GO:0007143(female meiotic nuclear division);GO:0010032(meiotic chromosome condensation);GO:0016020(membrane);GO:0030054(cell junction);GO:0030261(chromosome condensation);GO:0033077(T cell differentiation in thymus);GO:0045171(intercellular bridge);GO:0051276(chromosome organization);GO:0051306(mitotic sister chromatid separation);GO:0051309(female meiosis chromosome separation)","NA","K11490","NA","non-SMC condensin II complex subunit H2 [Source:HGNC Symbol;Acc:HGNC:25071]",{"v":0.123387,"d":"0.12"},{"v":0.069916,"d":"0.07"},0,{"v":0.044505,"d":"0.04"},{"v":0.130623,"d":"0.13"},0,{"v":1.1037812342972,"d":"1.10"},{"v":0.142454263176666,"d":"0.14"},1,1,"up","no"]
[130493,0,"chr21","+",39390860,39428326,"ENST00000650208",8,923,"ENSG00000182093","WRB","GO:0005634(nucleus);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0071816(tail-anchored membrane protein insertion into ER membrane)","NA","K22384","NA","tryptophan rich basic protein [Source:HGNC Symbol;Acc:HGNC:12790]",{"v":0.008011,"d":"0.01"},{"v":0.209679,"d":"0.21"},{"v":0.080309,"d":"0.08"},{"v":0.188307,"d":"0.19"},0,0,{"v":1.58251684748841,"d":"1.58"},{"v":0.662220858679588,"d":"0.66"},1,1,"up","no"]
[143413,0,"chr3","+",121939191,121940982,"ENST00000469422",3,562,"ENSG00000163406","SLC15A2","GO:0005215(transporter activity);GO:0005515(protein binding);GO:0005886(plasma membrane);GO:0005887(integral component of plasma membrane);GO:0006811(ion transport);GO:0006857(oligopeptide transport);GO:0015031(protein transport);GO:0015293(symporter activity);GO:0015333(peptide:proton symporter activity);GO:0015833(peptide transport);GO:0015893(drug transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0022857(transmembrane transporter activity);GO:0035442(dipeptide transmembrane transport);GO:0035672(oligopeptide transmembrane transport);GO:0035673(oligopeptide transmembrane transporter activity);GO:0055085(transmembrane transport);GO:0070062(extracellular exosome);GO:0071916(dipeptide transmembrane transporter activity);GO:1902600(proton transmembrane transport);GO:1904680(peptide transmembrane transporter activity)","NA","K14637","NA","solute carrier family 15 member 2 [Source:HGNC Symbol;Acc:HGNC:10921]",0,0,{"v":0.075559,"d":"0.08"},0,0,0,"inf","inf",1,1,"up","no"]
[99018,0,"chr19","+",11105307,11113624,"ENST00000560467",6,928,"ENSG00000130164","LDLR","GO:0001540(amyloid-beta binding);GO:0001618(virus receptor activity);GO:0002020(protease binding);GO:0005041(low-density lipoprotein particle receptor activity);GO:0005509(calcium ion binding);GO:0005515(protein binding);GO:0005623(cell);GO:0005764(lysosome);GO:0005768(endosome);GO:0005769(early endosome);GO:0005770(late endosome);GO:0005794(Golgi apparatus);GO:0005886(plasma membrane);GO:0005887(integral component of plasma membrane);GO:0005905(clathrin-coated pit);GO:0006629(lipid metabolic process);GO:0006869(lipid transport);GO:0006897(endocytosis);GO:0006898(receptor-mediated endocytosis);GO:0006909(phagocytosis);GO:0007616(long-term memory);GO:0008202(steroid metabolic process);GO:0008203(cholesterol metabolic process);GO:0009897(external side of plasma membrane);GO:0009986(cell surface);GO:0010008(endosome membrane);GO:0010628(positive regulation of gene expression);GO:0010629(negative regulation of gene expression);GO:0010867(positive regulation of triglyceride biosynthetic process);GO:0010899(regulation of phosphatidylcholine catabolic process);GO:0015914(phospholipid transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016032(viral process);GO:0016323(basolateral plasma membrane);GO:0030169(low-density lipoprotein particle binding);GO:0030229(very-low-density lipoprotein particle receptor activity);GO:0030299(intestinal cholesterol absorption);GO:0030301(cholesterol transport);GO:0030669(clathrin-coated endocytic vesicle membrane);GO:0032050(clathrin heavy chain binding);GO:0034362(low-density lipoprotein particle);GO:0034381(plasma lipoprotein particle clearance);GO:0034382(chylomicron remnant clearance);GO:0034383(low-density lipoprotein particle clearance);GO:0034384(high-density lipoprotein particle clearance);GO:0036020(endolysosome membrane);GO:0036477(somatodendritic compartment);GO:0042157(lipoprotein metabolic process);GO:0042159(lipoprotein catabolic process);GO:0042632(cholesterol homeostasis);GO:0042802(identical protein binding);GO:0043235(receptor complex);GO:0045177(apical part of cell);GO:0046718(viral entry into host cell);GO:0048844(artery morphogenesis);GO:0050729(positive regulation of inflammatory response);GO:0051246(regulation of protein metabolic process);GO:0051248(negative regulation of protein metabolic process);GO:0061024(membrane organization);GO:0061771(response to caloric restriction);GO:0061889(negative regulation of astrocyte activation);GO:0070508(cholesterol import);GO:0071398(cellular response to fatty acid);GO:0071404(cellular response to low-density lipoprotein particle stimulus);GO:0090118(receptor-mediated endocytosis involved in cholesterol transport);GO:0090181(regulation of cholesterol metabolic process);GO:0097242(amyloid-beta clearance);GO:0097443(sorting endosome);GO:0150094(amyloid-beta clearance by cellular catabolic process);GO:1903979(negative regulation of microglial cell activation);GO:1905167(positive regulation of lysosomal protein catabolic process);GO:1905907(negative regulation of amyloid fibril formation);GO:1990666(PCSK9-LDLR complex)","04144(Endocytosis);04913(Ovarian steroidogenesis);04925(Aldosterone synthesis and secretion);04927(Cortisol synthesis and secretion);04934(Cushing syndrome);04976(Bile secretion);04979(Cholesterol metabolism);05145(Toxoplasmosis);05160(Hepatitis C)","K12473","NA","low density lipoprotein receptor [Source:HGNC Symbol;Acc:HGNC:6547]",0,{"v":0.225997,"d":"0.23"},0,0,0,0,"inf","inf",1,1,"up","no"]
[45292,0,"chr12","+",65644397,65647855,"ENST00000545188",2,547,"ENSG00000256915","AC090023","NA","NA","NA","NA","novel transcript",0,0,0,0,0,0,1,0,1,1,"no","no"]
[69374,0,"chr16","+",681224,682213,"ENST00000566181",5,510,"ENSG00000103266","STUB1","GO:0000151(ubiquitin ligase complex);GO:0000209(protein polyubiquitination);GO:0001664(G protein-coupled receptor binding);GO:0002931(response to ischemia);GO:0004842(ubiquitin-protein transferase activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0005783(endoplasmic reticulum);GO:0005829(cytosol);GO:0006281(DNA repair);GO:0006511(ubiquitin-dependent protein catabolic process);GO:0006515(protein quality control for misfolded or incompletely synthesized proteins);GO:0006974(cellular response to DNA damage stimulus);GO:0016567(protein ubiquitination);GO:0016740(transferase activity);GO:0019899(enzyme binding);GO:0019900(kinase binding);GO:0030018(Z disc);GO:0030433(ubiquitin-dependent ERAD pathway);GO:0030512(negative regulation of transforming growth factor beta receptor signaling pathway);GO:0030544(Hsp70 protein binding);GO:0030579(ubiquitin-dependent SMAD protein catabolic process);GO:0030674(protein binding, bridging);GO:0030911(TPR domain binding);GO:0030968(endoplasmic reticulum unfolded protein response);GO:0031072(heat shock protein binding);GO:0031371(ubiquitin conjugating enzyme complex);GO:0031398(positive regulation of protein ubiquitination);GO:0031625(ubiquitin protein ligase binding);GO:0031647(regulation of protein stability);GO:0031943(regulation of glucocorticoid metabolic process);GO:0032091(negative regulation of protein binding);GO:0032436(positive regulation of proteasomal ubiquitin-dependent protein catabolic process);GO:0034450(ubiquitin-ubiquitin ligase activity);GO:0034605(cellular response to heat);GO:0038128(ERBB2 signaling pathway);GO:0042405(nuclear inclusion body);GO:0042803(protein homodimerization activity);GO:0043161(proteasome-mediated ubiquitin-dependent protein catabolic process);GO:0046332(SMAD binding);GO:0048156(tau protein binding);GO:0051087(chaperone binding);GO:0051443(positive regulation of ubiquitin-protein transferase activity);GO:0051604(protein maturation);GO:0051787(misfolded protein binding);GO:0051865(protein autoubiquitination);GO:0051879(Hsp90 protein binding);GO:0061630(ubiquitin protein ligase activity);GO:0061684(chaperone-mediated autophagy);GO:0070534(protein K63-linked ubiquitination);GO:0071218(cellular response to misfolded protein);GO:0071456(cellular response to hypoxia);GO:0090035(positive regulation of chaperone-mediated protein complex assembly);GO:0101031(chaperone complex)","04120(Ubiquitin mediated proteolysis);04141(Protein processing in endoplasmic reticulum)","K09561","EC:2.3.2.27","STIP1 homology and U-box containing protein 1 [Source:HGNC Symbol;Acc:HGNC:11427]",{"v":0.982127,"d":"0.98"},0,{"v":0.472633,"d":"0.47"},{"v":1.180045,"d":"1.18"},{"v":0.418498,"d":"0.42"},{"v":2.813266,"d":"2.81"},{"v":0.329742289387415,"d":"0.33"},{"v":-1.60058917064208,"d":"-1.60"},1,1,"down","no"]
[199061,0,"chr9","+",125241663,125257018,"ENST00000468244",3,550,"ENSG00000239705","AL354710","NA","NA","NA","NA","novel transcript",0,0,0,{"v":0.152904,"d":"0.15"},0,0,"-inf","-inf",1,1,"down","no"]
[99492,0,"chr19","-",12703757,12706282,"ENST00000589572",6,586,"ENSG00000105576","TNPO2","GO:0005515(protein binding);GO:0005623(cell);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0006606(protein import into nucleus);GO:0006607(NLS-bearing protein import into nucleus);GO:0006610(ribosomal protein import into nucleus);GO:0006886(intracellular protein transport);GO:0008139(nuclear localization sequence binding);GO:0008536(Ran GTPase binding);GO:0008565(protein transporter activity);GO:0015031(protein transport);GO:0031965(nuclear membrane);GO:0034399(nuclear periphery)","NA","K18727","NA","transportin 2 [Source:HGNC Symbol;Acc:HGNC:19998]",{"v":0.254705,"d":"0.25"},{"v":0.409713,"d":"0.41"},{"v":0.405826,"d":"0.41"},{"v":0.313462,"d":"0.31"},{"v":0.560729,"d":"0.56"},{"v":0.250147,"d":"0.25"},{"v":0.951888133283763,"d":"0.95"},{"v":-0.0711360581605549,"d":"-0.07"},1,1,"down","no"]
[122657,0,"chr2","-",224378698,224401994,"ENST00000389874",3,2594,"ENSG00000124019","FAM124B","GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005739(mitochondrion)","NA","NA","NA","family with sequence similarity 124 member B [Source:HGNC Symbol;Acc:HGNC:26224]",0,{"v":0.016905,"d":"0.02"},{"v":0.01695,"d":"0.02"},0,{"v":0.019715,"d":"0.02"},{"v":0.034127,"d":"0.03"},{"v":0.62878422049701,"d":"0.63"},{"v":-0.669363081642555,"d":"-0.67"},1,1,"down","no"]
[56523,0,"chr14","-",50725827,50830479,"ENST00000382043",28,4216,"ENSG00000100503","NIN","GO:0000166(nucleotide binding);GO:0000242(pericentriolar material);GO:0000922(spindle pole);GO:0005509(calcium ion binding);GO:0005515(protein binding);GO:0005525(GTP binding);GO:0005634(nucleus);GO:0005730(nucleolus);GO:0005737(cytoplasm);GO:0005813(centrosome);GO:0005814(centriole);GO:0005815(microtubule organizing center);GO:0005856(cytoskeleton);GO:0005874(microtubule);GO:0005886(plasma membrane);GO:0008104(protein localization);GO:0010457(centriole-centriole cohesion);GO:0019900(kinase binding);GO:0021540(corpus callosum morphogenesis);GO:0021957(corticospinal tract morphogenesis);GO:0030424(axon);GO:0030425(dendrite);GO:0031116(positive regulation of microtubule polymerization);GO:0034454(microtubule anchoring at centrosome);GO:0036449(microtubule minus-end);GO:0044295(axonal growth cone);GO:0045177(apical part of cell);GO:0048668(collateral sprouting);GO:0050772(positive regulation of axonogenesis);GO:0051642(centrosome localization);GO:0072686(mitotic spindle);GO:0090222(centrosome-templated microtubule nucleation);GO:0097431(mitotic spindle pole);GO:0097539(ciliary transition fiber);GO:0120103(centriolar subdistal appendage)","NA","K16476","NA","ninein [Source:HGNC Symbol;Acc:HGNC:14906]",{"v":0.054479,"d":"0.05"},{"v":0.013309,"d":"0.01"},{"v":0.084447,"d":"0.08"},{"v":0.008794,"d":"0.01"},{"v":0.028765,"d":"0.03"},0,{"v":4.05322292925797,"d":"4.05"},{"v":2.01906952650496,"d":"2.02"},1,1,"up","no"]
[168033,0,"chr6","+",26383126,26388249,"ENST00000472507",3,535,"ENSG00000124508","BTN2A2","GO:0005102(signaling receptor binding);GO:0005515(protein binding);GO:0005886(plasma membrane);GO:0009897(external side of plasma membrane);GO:0009986(cell surface);GO:0014067(negative regulation of phosphatidylinositol 3-kinase signaling);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0031324(negative regulation of cellular metabolic process);GO:0045591(positive regulation of regulatory T cell differentiation);GO:0046007(negative regulation of activated T cell proliferation);GO:0050710(negative regulation of cytokine secretion);GO:0050776(regulation of immune response);GO:0050852(T cell receptor signaling pathway);GO:0050860(negative regulation of T cell receptor signaling pathway);GO:0051898(negative regulation of protein kinase B signaling);GO:0070373(negative regulation of ERK1 and ERK2 cascade);GO:2000134(negative regulation of G1/S transition of mitotic cell cycle)","NA","K06712","NA","butyrophilin subfamily 2 member A2 [Source:HGNC Symbol;Acc:HGNC:1137]",0,{"v":0.00284,"d":"0.00"},0,{"v":0.013264,"d":"0.01"},0,{"v":0.025247,"d":"0.03"},{"v":0.0737451637194568,"d":"0.07"},{"v":-3.76130775067376,"d":"-3.76"},1,1,"down","no"]
[30579,0,"chr11","-",58497915,58505595,"ENST00000528978",4,562,"ENSG00000255299","AP003557","NA","NA","NA","NA","novel transcript",0,0,0,0,0,0,1,0,1,1,"no","no"]
[57941,0,"chr14","+",69398390,69458827,"ENST00000538956",8,1264,"ENSG00000029364","SLC39A9","GO:0006811(ion transport);GO:0006829(zinc ion transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0030001(metal ion transport);GO:0046873(metal ion transmembrane transporter activity);GO:0055085(transmembrane transport)","NA","K14715","NA","solute carrier family 39 member 9 [Source:HGNC Symbol;Acc:HGNC:20182]",0,{"v":0.265325,"d":"0.27"},0,{"v":0.061891,"d":"0.06"},0,{"v":0.130054,"d":"0.13"},{"v":1.38229701216494,"d":"1.38"},{"v":0.46706763883672,"d":"0.47"},1,1,"up","no"]
[197944,0,"chr9","-",99366417,99372512,"ENST00000605707",3,1748,"ENSG00000271086","NAMA","NA","NA","NA","NA","non-protein coding RNA, associated with MAP kinase pathway and growth arrest [Source:HGNC Symbol;Acc:HGNC:42408]",0,0,0,0,0,0,1,0,1,1,"no","no"]
[168891,0,"chr6","-",31164337,31180731,"ENST00000441888",5,1055,"ENSG00000204531","POU5F1","GO:0000122(negative regulation of transcription by RNA polymerase II);GO:0000790(nuclear chromatin);GO:0000976(transcription regulatory region sequence-specific DNA binding);GO:0000981(DNA-binding transcription factor activity, RNA polymerase II-specific);GO:0001158(enhancer sequence-specific DNA binding);GO:0001227(DNA-binding transcription repressor activity, RNA polymerase II-specific);GO:0001714(endodermal cell fate specification);GO:0001824(blastocyst development);GO:0003677(DNA binding);GO:0003700(DNA-binding transcription factor activity);GO:0003723(RNA binding);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0005739(mitochondrion);GO:0005829(cytosol);GO:0006355(regulation of transcription, DNA-templated);GO:0006366(transcription by RNA polymerase II);GO:0007275(multicellular organism development);GO:0009611(response to wounding);GO:0009653(anatomical structure morphogenesis);GO:0009786(regulation of asymmetric cell division);GO:0010468(regulation of gene expression);GO:0010628(positive regulation of gene expression);GO:0010629(negative regulation of gene expression);GO:0019955(cytokine binding);GO:0031625(ubiquitin protein ligase binding);GO:0035019(somatic stem cell population maintenance);GO:0035198(miRNA binding);GO:0042789(mRNA transcription by RNA polymerase II);GO:0043565(sequence-specific DNA binding);GO:0045944(positive regulation of transcription by RNA polymerase II);GO:0060965(negative regulation of gene silencing by miRNA)","04550(Signaling pathways regulating pluripotency of stem cells)","NA","NA","POU class 5 homeobox 1 [Source:HGNC Symbol;Acc:HGNC:9221]",0,0,0,0,0,{"v":0.01565,"d":"0.02"},"-inf","-inf",1,1,"down","no"]
[29817,0,"chr11","-",47220218,47221751,"ENST00000540410",2,610,"ENSG00000256897","AC018410","NA","NA","NA","NA","novel transcript",{"v":0.068837,"d":"0.07"},{"v":0.199337,"d":"0.20"},{"v":0.069866,"d":"0.07"},{"v":0.056193,"d":"0.06"},0,0,{"v":6.01569590518392,"d":"6.02"},{"v":2.58873164029156,"d":"2.59"},1,1,"up","no"]
[140534,0,"chr3","-",51971337,51974079,"ENST00000473912",2,477,"ENSG00000114779","ABHD14B","GO:0005515(protein binding);GO:0005634(nucleus);GO:0005730(nucleolus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0016787(hydrolase activity);GO:0045944(positive regulation of transcription by RNA polymerase II);GO:0050427(3'-phosphoadenosine 5'-phosphosulfate metabolic process);GO:0070062(extracellular exosome)","NA","K13706","NA","abhydrolase domain containing 14B [Source:HGNC Symbol;Acc:HGNC:28235]",{"v":0.326182,"d":"0.33"},{"v":0.398414,"d":"0.40"},{"v":0.253471,"d":"0.25"},{"v":0.175777,"d":"0.18"},{"v":0.519906,"d":"0.52"},{"v":0.188957,"d":"0.19"},{"v":1.1056101917164,"d":"1.11"},{"v":0.144842819926133,"d":"0.14"},1,1,"up","no"]
[145634,0,"chr3","-",154276029,154277835,"ENST00000495598",3,719,"ENSG00000174953","DHX36","GO:0000166(nucleotide binding);GO:0000287(magnesium ion binding);GO:0000781(chromosome, telomeric region);GO:0000978(RNA polymerase II proximal promoter sequence-specific DNA binding);GO:0001503(ossification);GO:0002151(G-quadruplex RNA binding);GO:0002376(immune system process);GO:0002735(positive regulation of myeloid dendritic cell cytokine production);GO:0003676(nucleic acid binding);GO:0003677(DNA binding);GO:0003697(single-stranded DNA binding);GO:0003723(RNA binding);GO:0003725(double-stranded RNA binding);GO:0003730(mRNA 3'-UTR binding);GO:0004003(ATP-dependent DNA helicase activity);GO:0004004(ATP-dependent RNA helicase activity);GO:0004386(helicase activity);GO:0005515(protein binding);GO:0005524(ATP binding);GO:0005634(nucleus);GO:0005694(chromosome);GO:0005737(cytoplasm);GO:0005739(mitochondrion);GO:0005829(cytosol);GO:0006359(regulation of transcription by RNA polymerase III);GO:0006417(regulation of translation);GO:0007275(multicellular organism development);GO:0007283(spermatogenesis);GO:0008094(DNA-dependent ATPase activity);GO:0009615(response to virus);GO:0010494(cytoplasmic stress granule);GO:0010501(RNA secondary structure unwinding);GO:0010628(positive regulation of gene expression);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016607(nuclear speck);GO:0016787(hydrolase activity);GO:0017148(negative regulation of translation);GO:0030154(cell differentiation);GO:0030424(axon);GO:0030425(dendrite);GO:0031442(positive regulation of mRNA 3'-end processing);GO:0032206(positive regulation of telomere maintenance);GO:0032481(positive regulation of type I interferon production);GO:0032508(DNA duplex unwinding);GO:0034459(ATP-dependent 3'-5' RNA helicase activity);GO:0034605(cellular response to heat);GO:0034644(cellular response to UV);GO:0035925(mRNA 3'-UTR AU-rich region binding);GO:0042826(histone deacetylase binding);GO:0042995(cell projection);GO:0043123(positive regulation of I-kappaB kinase/NF-kappaB signaling);GO:0043204(perikaryon);GO:0043330(response to exogenous dsRNA);GO:0043488(regulation of mRNA stability);GO:0044212(transcription regulatory region DNA binding);GO:0044806(G-quadruplex DNA unwinding);GO:0045087(innate immune response);GO:0045944(positive regulation of transcription by RNA polymerase II);GO:0045995(regulation of embryonic development);GO:0046872(metal ion binding);GO:0048027(mRNA 5'-UTR binding);GO:0051607(defense response to virus);GO:0051880(G-quadruplex DNA binding);GO:0051891(positive regulation of cardioblast differentiation);GO:0060261(positive regulation of transcription initiation from RNA polymerase II promoter);GO:0061003(positive regulation of dendritic spine morphogenesis);GO:0061158(3'-UTR-mediated mRNA destabilization);GO:0070034(telomerase RNA binding);GO:0070062(extracellular exosome);GO:0070883(pre-miRNA binding);GO:0090669(telomerase RNA stabilization);GO:1900153(positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay);GO:1901534(positive regulation of hematopoietic progenitor cell differentiation);GO:1902064(regulation of transcription from RNA polymerase II promoter involved in spermatogenesis);GO:1902741(positive regulation of interferon-alpha secretion);GO:1903843(cellular response to arsenite ion);GO:1904358(positive regulation of telomere maintenance via telomere lengthening);GO:1904582(positive regulation of intracellular mRNA localization);GO:2000767(positive regulation of cytoplasmic translation)","03018(RNA degradation)","K14442","EC:3.6.4.13","DEAH-box helicase 36 [Source:HGNC Symbol;Acc:HGNC:14410]",{"v":0.297946,"d":"0.30"},{"v":0.293812,"d":"0.29"},{"v":0.395414,"d":"0.40"},{"v":0.287122,"d":"0.29"},{"v":0.402411,"d":"0.40"},{"v":0.317581,"d":"0.32"},{"v":0.980198865272452,"d":"0.98"},{"v":-0.028853618275129,"d":"-0.03"},1,1,"down","no"]
[29545,0,"chr11","-",45905941,45906461,"ENST00000533218",2,409,"ENSG00000255498","AC068385","NA","NA","NA","NA","novel transcript",0,0,{"v":0.010674,"d":"0.01"},0,{"v":0.023838,"d":"0.02"},0,{"v":0.447772464132897,"d":"0.45"},{"v":-1.15916228282094,"d":"-1.16"},1,1,"down","no"]
[33748,0,"chr11","-",72024305,72070093,"ENST00000535838",5,582,"ENSG00000137497","NUMA1","GO:0000132(establishment of mitotic spindle orientation);GO:0000139(Golgi membrane);GO:0000922(spindle pole);GO:0001578(microtubule bundle formation);GO:0005198(structural molecule activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005694(chromosome);GO:0005737(cytoplasm);GO:0005813(centrosome);GO:0005815(microtubule organizing center);GO:0005819(spindle);GO:0005829(cytosol);GO:0005856(cytoskeleton);GO:0005874(microtubule);GO:0005876(spindle microtubule);GO:0005886(plasma membrane);GO:0005938(cell cortex);GO:0006997(nucleus organization);GO:0007049(cell cycle);GO:0007059(chromosome segregation);GO:0008017(microtubule binding);GO:0008022(protein C-terminus binding);GO:0008289(lipid binding);GO:0015631(tubulin binding);GO:0016020(membrane);GO:0016328(lateral plasma membrane);GO:0016363(nuclear matrix);GO:0019897(extrinsic component of plasma membrane);GO:0019904(protein domain specific binding);GO:0030425(dendrite);GO:0030513(positive regulation of BMP signaling pathway);GO:0030953(astral microtubule organization);GO:0031116(positive regulation of microtubule polymerization);GO:0031616(spindle pole centrosome);GO:0032388(positive regulation of intracellular transport);GO:0032991(protein-containing complex);GO:0035091(phosphatidylinositol binding);GO:0035371(microtubule plus-end);GO:0036449(microtubule minus-end);GO:0043025(neuronal cell body);GO:0044877(protein-containing complex binding);GO:0045618(positive regulation of keratinocyte differentiation);GO:0051010(microtubule plus-end binding);GO:0051011(microtubule minus-end binding);GO:0051301(cell division);GO:0051321(meiotic cell cycle);GO:0051798(positive regulation of hair follicle development);GO:0051984(positive regulation of chromosome segregation);GO:0055028(cortical microtubule);GO:0055048(anastral spindle assembly);GO:0060236(regulation of mitotic spindle organization);GO:0061673(mitotic spindle astral microtubule);GO:0070062(extracellular exosome);GO:0070840(dynein complex binding);GO:0072686(mitotic spindle);GO:0090235(regulation of metaphase plate congression);GO:0097427(microtubule bundle);GO:0097431(mitotic spindle pole);GO:0097575(lateral cell cortex);GO:0097718(disordered domain specific binding);GO:0099738(cell cortex region);GO:1902365(positive regulation of protein localization to spindle pole body);GO:1902846(positive regulation of mitotic spindle elongation);GO:1904778(positive regulation of protein localization to cell cortex);GO:1905720(cytoplasmic microtubule bundle);GO:1905820(positive regulation of chromosome separation);GO:1905832(positive regulation of spindle assembly);GO:1990023(mitotic spindle midzone)","NA","K16808","NA","nuclear mitotic apparatus protein 1 [Source:HGNC Symbol;Acc:HGNC:8059]",{"v":0.131666,"d":"0.13"},0,{"v":0.142246,"d":"0.14"},0,{"v":0.467988,"d":"0.47"},{"v":0.391523,"d":"0.39"},{"v":0.318683530519098,"d":"0.32"},{"v":-1.64980363194474,"d":"-1.65"},1,1,"down","no"]
[11852,0,"chr1","+",154975032,154979125,"ENST00000477676",3,602,"ENSG00000173207","CKS1B","GO:0000079(regulation of cyclin-dependent protein serine/threonine kinase activity);GO:0000307(cyclin-dependent protein kinase holoenzyme complex);GO:0005515(protein binding);GO:0005654(nucleoplasm);GO:0006355(regulation of transcription, DNA-templated);GO:0007049(cell cycle);GO:0007346(regulation of mitotic cell cycle);GO:0008283(cell population proliferation);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0016538(cyclin-dependent protein serine/threonine kinase regulator activity);GO:0019005(SCF ubiquitin ligase complex);GO:0019901(protein kinase binding);GO:0042393(histone binding);GO:0043130(ubiquitin binding);GO:0044772(mitotic cell cycle phase transition);GO:0045737(positive regulation of cyclin-dependent protein serine/threonine kinase activity);GO:0051301(cell division);GO:0061575(cyclin-dependent protein serine/threonine kinase activator activity)","05200(Pathways in cancer);05222(Small cell lung cancer)","NA","NA","CDC28 protein kinase regulatory subunit 1B [Source:HGNC Symbol;Acc:HGNC:19083]",{"v":0.01475,"d":"0.01"},{"v":0.003629,"d":"0.00"},0,{"v":0.019477,"d":"0.02"},0,{"v":0.026102,"d":"0.03"},{"v":0.403233945457338,"d":"0.40"},{"v":-1.31031100049011,"d":"-1.31"},1,1,"down","no"]
[17375,0,"chr1","+",229508501,229514272,"ENST00000417605",3,591,"ENSG00000223635","AL121990","NA","NA","NA","NA","novel transcript",0,0,0,0,0,0,1,0,1,1,"no","no"]
[197957,0,"chr9","+",99906673,99929169,"ENST00000533696",3,611,"ENSG00000136874","STX17","GO:0000149(SNARE binding);GO:0000421(autophagosome membrane);GO:0005484(SNAP receptor activity);GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0005739(mitochondrion);GO:0005776(autophagosome);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005793(endoplasmic reticulum-Golgi intermediate compartment);GO:0005829(cytosol);GO:0006886(intracellular protein transport);GO:0006888(endoplasmic reticulum to Golgi vesicle-mediated transport);GO:0006906(vesicle fusion);GO:0006914(autophagy);GO:0007030(Golgi organization);GO:0012505(endomembrane system);GO:0012507(ER to Golgi transport vesicle membrane);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016192(vesicle-mediated transport);GO:0016240(autophagosome membrane docking);GO:0019901(protein kinase binding);GO:0019903(protein phosphatase binding);GO:0030134(COPII-coated ER to Golgi transport vesicle);GO:0030868(smooth endoplasmic reticulum membrane);GO:0030897(HOPS complex);GO:0031201(SNARE complex);GO:0031410(cytoplasmic vesicle);GO:0033116(endoplasmic reticulum-Golgi intermediate compartment membrane);GO:0034497(protein localization to phagophore assembly site);GO:0044233(mitochondria-associated endoplasmic reticulum membrane);GO:0048278(vesicle docking);GO:0097111(endoplasmic reticulum-Golgi intermediate compartment organization);GO:0097352(autophagosome maturation)","04130(SNARE interactions in vesicular transport);04140(Autophagy - animal)","K08491","NA","syntaxin 17 [Source:HGNC Symbol;Acc:HGNC:11432]",{"v":0.000404,"d":"0.00"},{"v":0.000824,"d":"0.00"},{"v":0.000394,"d":"0.00"},{"v":0.045391,"d":"0.05"},{"v":0.001785,"d":"0.00"},{"v":0.047365,"d":"0.05"},{"v":0.0171565775695201,"d":"0.02"},{"v":-5.8650944001029,"d":"-5.87"},1,1,"down","no"]
[148273,0,"chr3","+",195658065,195664109,"ENST00000452844",5,583,"ENSG00000242086","MUC20-OT1","NA","NA","NA","NA","MUC20 overlapping transcript [Source:HGNC Symbol;Acc:HGNC:53807]",0,0,0,0,0,{"v":0.285607,"d":"0.29"},"-inf","-inf",1,1,"down","no"]
[76286,0,"chr16","+",67227213,67228622,"ENST00000564087",4,518,"ENSG00000168701","TMEM208","GO:0005773(vacuole);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0006624(vacuolar protein processing);GO:0006914(autophagy);GO:0016020(membrane);GO:0016021(integral component of membrane)","NA","NA","NA","transmembrane protein 208 [Source:HGNC Symbol;Acc:HGNC:25015]",0,0,{"v":0.116652,"d":"0.12"},{"v":0.231576,"d":"0.23"},0,{"v":0.150939,"d":"0.15"},{"v":0.304960589780793,"d":"0.30"},{"v":-1.7133052804134,"d":"-1.71"},1,1,"down","no"]
[43967,0,"chr12","-",55803689,55822719,"ENST00000552719",5,531,"ENSG00000257390","AC023055","GO:0005515(protein binding);GO:0016607(nuclear speck);GO:0036464(cytoplasmic ribonucleoprotein granule)","NA","NA","NA","novel protein",0,{"v":0.071221,"d":"0.07"},0,0,0,0,"inf","inf",1,1,"up","no"]
[175380,0,"chr6","+",159383531,159396443,"ENST00000429657",3,772,"ENSG00000234777","LINC02529","NA","NA","NA","NA","long intergenic non-protein coding RNA 2529 [Source:HGNC Symbol;Acc:HGNC:53555]",0,0,0,0,{"v":0.201593,"d":"0.20"},0,"-inf","-inf",1,1,"down","no"]
[196947,0,"chr9","-",83244622,83538401,"ENST00000304195",14,5260,"ENSG00000172159","FRMD3","GO:0005856(cytoskeleton);GO:0008092(cytoskeletal protein binding);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0031032(actomyosin structure organization)","NA","NA","NA","FERM domain containing 3 [Source:HGNC Symbol;Acc:HGNC:24125]",{"v":0.135003,"d":"0.14"},{"v":0.103989,"d":"0.10"},{"v":0.124792,"d":"0.12"},{"v":0.035576,"d":"0.04"},{"v":0.053824,"d":"0.05"},{"v":0.085384,"d":"0.09"},{"v":2.08133467594288,"d":"2.08"},{"v":1.05750896723633,"d":"1.06"},1,1,"up","no"]
[112918,0,"chr2","+",62942718,62956117,"ENST00000469591",4,886,"ENSG00000115504","EHBP1","GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0005768(endosome);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0006897(endocytosis);GO:0015031(protein transport);GO:0016020(membrane)","NA","NA","NA","EH domain binding protein 1 [Source:HGNC Symbol;Acc:HGNC:29144]",{"v":0.212704,"d":"0.21"},{"v":0.179863,"d":"0.18"},{"v":0.243617,"d":"0.24"},{"v":0.797487,"d":"0.80"},{"v":0.528037,"d":"0.53"},{"v":0.360496,"d":"0.36"},{"v":0.377328857308929,"d":"0.38"},{"v":-1.40610565627003,"d":"-1.41"},1,1,"down","no"]
[56971,0,"chr14","-",57202483,57268899,"ENST00000413566",20,8513,"ENSG00000070367","EXOC5","GO:0000145(exocyst);GO:0001736(establishment of planar polarity);GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0006887(exocytosis);GO:0006892(post-Golgi vesicle-mediated transport);GO:0006893(Golgi to plasma membrane transport);GO:0015031(protein transport);GO:0017160(Ral GTPase binding);GO:0030496(midbody);GO:0047485(protein N-terminus binding);GO:0048278(vesicle docking);GO:0048873(homeostasis of number of cells within a tissue);GO:0072659(protein localization to plasma membrane);GO:1904019(epithelial cell apoptotic process);GO:1905515(non-motile cilium assembly)","NA","K19984","NA","exocyst complex component 5 [Source:HGNC Symbol;Acc:HGNC:10696]",{"v":8.7e-5,"d":"0.00"},{"v":0.014536,"d":"0.01"},{"v":0.028368,"d":"0.03"},{"v":0.017134,"d":"0.02"},{"v":0.087004,"d":"0.09"},0,{"v":0.412827210048205,"d":"0.41"},{"v":-1.27639003084161,"d":"-1.28"},1,1,"down","no"]
[159887,0,"chr5","+",72381794,72382393,"ENST00000494700",1,600,"ENSG00000244061","AC093278","NA","NA","NA","NA","ribosomal protein L10a (RPL10A) pseudogene",{"v":0.069984,"d":"0.07"},0,{"v":0.043916,"d":"0.04"},0,0,0,"inf","inf",1,1,"up","no"]
[103307,0,"chr19","-",38212072,38213979,"ENST00000488378",3,480,"ENSG00000011332","DPF1","GO:0000123(histone acetyltransferase complex);GO:0000790(nuclear chromatin);GO:0003676(nucleic acid binding);GO:0004402(histone acetyltransferase activity);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0006915(apoptotic process);GO:0007399(nervous system development);GO:0008270(zinc ion binding);GO:0016573(histone acetylation);GO:0042393(histone binding);GO:0045892(negative regulation of transcription, DNA-templated);GO:0045944(positive regulation of transcription by RNA polymerase II);GO:0046872(metal ion binding);GO:0071565(nBAF complex)","04714(Thermogenesis);05225(Hepatocellular carcinoma)","NA","NA","double PHD fingers 1 [Source:HGNC Symbol;Acc:HGNC:20225]",{"v":0.045294,"d":"0.05"},{"v":0.08899,"d":"0.09"},{"v":0.002325,"d":"0.00"},{"v":0.111767,"d":"0.11"},0,0,{"v":1.22226596401442,"d":"1.22"},{"v":0.289558248507462,"d":"0.29"},1,1,"up","no"]
[81090,0,"chr17","+",7631309,7632057,"ENST00000576747",2,522,"ENSG00000129214","SHBG","GO:0005496(steroid binding);GO:0005497(androgen binding);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0008289(lipid binding);GO:0070062(extracellular exosome)","NA","NA","NA","sex hormone binding globulin [Source:HGNC Symbol;Acc:HGNC:10839]",{"v":0.022654,"d":"0.02"},{"v":0.022272,"d":"0.02"},{"v":0.041916,"d":"0.04"},{"v":0.084254,"d":"0.08"},0,{"v":0.100595,"d":"0.10"},{"v":0.469799674328777,"d":"0.47"},{"v":-1.08988238163181,"d":"-1.09"},1,1,"down","no"]
[94494,0,"chr18","-",46826764,46906230,"ENST00000592212",12,2790,"ENSG00000078043","PIAS2","GO:0003677(DNA binding);GO:0003713(transcription coactivator activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0008134(transcription factor binding);GO:0008270(zinc ion binding);GO:0016605(PML body);GO:0016607(nuclear speck);GO:0016740(transferase activity);GO:0016925(protein sumoylation);GO:0019789(SUMO transferase activity);GO:0030521(androgen receptor signaling pathway);GO:0031625(ubiquitin protein ligase binding);GO:0045893(positive regulation of transcription, DNA-templated);GO:0046872(metal ion binding);GO:0050681(androgen receptor binding);GO:0060766(negative regulation of androgen receptor signaling pathway);GO:0061665(SUMO ligase activity)","04120(Ubiquitin mediated proteolysis);04630(Jak-STAT signaling pathway)","NA","NA","protein inhibitor of activated STAT 2 [Source:HGNC Symbol;Acc:HGNC:17311]",{"v":0.310714,"d":"0.31"},{"v":0.120655,"d":"0.12"},{"v":0.241552,"d":"0.24"},{"v":0.190221,"d":"0.19"},{"v":0.156788,"d":"0.16"},{"v":0.14294,"d":"0.14"},{"v":1.37345111429965,"d":"1.37"},{"v":0.457805561005253,"d":"0.46"},1,1,"up","no"]
[74497,0,"chr16","-",46469662,46478487,"ENST00000566933",3,658,"ENSG00000261239","ANKRD26P1","NA","NA","NA","NA","ankyrin repeat domain 26 pseudogene 1 [Source:HGNC Symbol;Acc:HGNC:32955]",0,0,0,0,0,0,1,0,1,1,"no","no"]
[105319,0,"chr19","+",45641647,45642357,"ENST00000587092",2,599,"ENSG00000267757","EML2-AS1","NA","NA","NA","NA","EML2 antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:48331]",{"v":0.049836,"d":"0.05"},0,{"v":0.016006,"d":"0.02"},{"v":0.01243,"d":"0.01"},{"v":0.04024,"d":"0.04"},{"v":0.023588,"d":"0.02"},{"v":0.863411051955205,"d":"0.86"},{"v":-0.211880534982462,"d":"-0.21"},1,1,"down","no"]
[16603,0,"chr1","-",219609606,219613069,"ENST00000367211",3,2997,"ENSG00000215817","ZC3H11B","GO:0046872(metal ion binding)","NA","K22415","NA","zinc finger CCCH-type containing 11B [Source:HGNC Symbol;Acc:HGNC:25659]",0,0,0,0,0,0,1,0,1,1,"no","no"]
[162843,0,"chr5","-",135028553,135034634,"ENST00000506438",4,1305,"ENSG00000069011","PITX1","GO:0000978(RNA polymerase II proximal promoter sequence-specific DNA binding);GO:0000981(DNA-binding transcription factor activity, RNA polymerase II-specific);GO:0001085(RNA polymerase II transcription factor binding);GO:0001228(DNA-binding transcription activator activity, RNA polymerase II-specific);GO:0001501(skeletal system development);GO:0003677(DNA binding);GO:0003700(DNA-binding transcription factor activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005667(transcription factor complex);GO:0005730(nucleolus);GO:0005737(cytoplasm);GO:0006355(regulation of transcription, DNA-templated);GO:0007275(multicellular organism development);GO:0009653(anatomical structure morphogenesis);GO:0014707(branchiomeric skeletal muscle development);GO:0021983(pituitary gland development);GO:0035116(embryonic hindlimb morphogenesis);GO:0035137(hindlimb morphogenesis);GO:0043565(sequence-specific DNA binding);GO:0045892(negative regulation of transcription, DNA-templated);GO:0045944(positive regulation of transcription by RNA polymerase II);GO:0048625(myoblast fate commitment);GO:0051216(cartilage development)","NA","K09356","NA","paired like homeodomain 1 [Source:HGNC Symbol;Acc:HGNC:9004]",0,0,0,0,{"v":0.021711,"d":"0.02"},0,"-inf","-inf",1,1,"down","no"]
[152481,0,"chr4","+",78768499,78768750,"ENST00000478593",1,252,"ENSG00000239793","AC098818","NA","NA","NA","NA","ribosomal protein S21 (RPS21) pseudogene",0,0,0,0,0,0,1,0,1,1,"no","no"]
[22847,0,"chr10","+",87945502,87946024,"ENST00000395256",1,523,"ENSG00000213613","RPL11P3","NA","NA","NA","NA","ribosomal protein L11 pseudogene 3 [Source:HGNC Symbol;Acc:HGNC:36342]",{"v":0.057187,"d":"0.06"},0,0,{"v":0.056165,"d":"0.06"},0,{"v":0.168966,"d":"0.17"},{"v":0.25401655036401,"d":"0.25"},{"v":-1.97700559651113,"d":"-1.98"},1,1,"down","no"]
[138996,0,"chr3","+",44555193,44583445,"ENST00000431636",6,1692,"ENSG00000196345","ZKSCAN7","GO:0000981(DNA-binding transcription factor activity, RNA polymerase II-specific);GO:0003676(nucleic acid binding);GO:0003677(DNA binding);GO:0003700(DNA-binding transcription factor activity);GO:0005515(protein binding);GO:0005622(intracellular);GO:0005634(nucleus);GO:0006355(regulation of transcription, DNA-templated);GO:0006357(regulation of transcription by RNA polymerase II);GO:0046872(metal ion binding)","NA","K09229","NA","zinc finger with KRAB and SCAN domains 7 [Source:HGNC Symbol;Acc:HGNC:12955]",0,{"v":0.034458,"d":"0.03"},0,0,{"v":0.140708,"d":"0.14"},0,{"v":0.244890127071666,"d":"0.24"},{"v":-2.0297934831409,"d":"-2.03"},1,1,"down","no"]
[152201,0,"chr4","-",75491911,75514764,"ENST00000514021",5,436,"ENSG00000163743","RCHY1","GO:0000151(ubiquitin ligase complex);GO:0002039(p53 binding);GO:0004842(ubiquitin-protein transferase activity);GO:0005102(signaling receptor binding);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0006511(ubiquitin-dependent protein catabolic process);GO:0008270(zinc ion binding);GO:0016567(protein ubiquitination);GO:0016607(nuclear speck);GO:0016740(transferase activity);GO:0031398(positive regulation of protein ubiquitination);GO:0032436(positive regulation of proteasomal ubiquitin-dependent protein catabolic process);GO:0042803(protein homodimerization activity);GO:0046872(metal ion binding);GO:0070987(error-free translesion synthesis)","04115(p53 signaling pathway);04120(Ubiquitin mediated proteolysis);05162(Measles)","K10144","EC:2.3.2.27","ring finger and CHY zinc finger domain containing 1 [Source:HGNC Symbol;Acc:HGNC:17479]",0,0,0,0,0,{"v":0.102497,"d":"0.10"},"-inf","-inf",1,1,"down","no"]
[175268,0,"chr6","+",157629389,157673937,"ENST00000523706",6,5146,"ENSG00000175048","ZDHHC14","GO:0005783(endoplasmic reticulum);GO:0005794(Golgi apparatus);GO:0006612(protein targeting to membrane);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016409(palmitoyltransferase activity);GO:0016740(transferase activity);GO:0016746(transferase activity, transferring acyl groups);GO:0018230(peptidyl-L-cysteine S-palmitoylation);GO:0018345(protein palmitoylation);GO:0019706(protein-cysteine S-palmitoyltransferase activity)","NA","NA","NA","zinc finger DHHC-type containing 14 [Source:HGNC Symbol;Acc:HGNC:20341]",{"v":0.008389,"d":"0.01"},0,{"v":0.005547,"d":"0.01"},{"v":0.002022,"d":"0.00"},0,0,{"v":6.8921859545005,"d":"6.89"},{"v":2.78496162669585,"d":"2.78"},1,1,"up","no"]
[161217,0,"chr5","-",96741079,96742698,"ENST00000502568",2,565,"ENSG00000249180","AC020900","NA","NA","NA","NA","novel transcript",{"v":0.093611,"d":"0.09"},{"v":0.115868,"d":"0.12"},{"v":0.143608,"d":"0.14"},{"v":0.314908,"d":"0.31"},{"v":0.329754,"d":"0.33"},{"v":0.179577,"d":"0.18"},{"v":0.428379389958495,"d":"0.43"},{"v":-1.22303902357589,"d":"-1.22"},1,1,"down","no"]
[137441,0,"chr3","-",18348885,18353084,"ENST00000606296",1,4200,"ENSG00000182568","SATB1","GO:0000122(negative regulation of transcription by RNA polymerase II);GO:0000785(chromatin);GO:0000977(RNA polymerase II regulatory region sequence-specific DNA binding);GO:0000981(DNA-binding transcription factor activity, RNA polymerase II-specific);GO:0001227(DNA-binding transcription repressor activity, RNA polymerase II-specific);GO:0003677(DNA binding);GO:0003682(chromatin binding);GO:0003690(double-stranded DNA binding);GO:0003700(DNA-binding transcription factor activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005720(nuclear heterochromatin);GO:0006325(chromatin organization);GO:0006338(chromatin remodeling);GO:0006355(regulation of transcription, DNA-templated);GO:0008544(epidermis development);GO:0016032(viral process);GO:0016363(nuclear matrix);GO:0016571(histone methylation);GO:0016604(nuclear body);GO:0016605(PML body);GO:0042110(T cell activation);GO:0043367(CD4-positive, alpha-beta T cell differentiation);GO:0043374(CD8-positive, alpha-beta T cell differentiation);GO:0043565(sequence-specific DNA binding);GO:0050798(activated T cell proliferation);GO:0060004(reflex)","NA","K23225","NA","SATB homeobox 1 [Source:HGNC Symbol;Acc:HGNC:10541]",{"v":0.045343,"d":"0.05"},{"v":0.206331,"d":"0.21"},{"v":0.0732,"d":"0.07"},{"v":0.066522,"d":"0.07"},{"v":0.075866,"d":"0.08"},{"v":0.018585,"d":"0.02"},{"v":2.01818938579762,"d":"2.02"},{"v":1.01306156251709,"d":"1.01"},1,1,"up","no"]
[198182,0,"chr9","-",107169569,107171148,"ENST00000415694",1,1580,"ENSG00000226535","AL445487","NA","NA","NA","NA","karyopherin alpha 2 (RAG cohort 1, importin alpha 1) (KPNA2) pseudogene",0,0,0,0,{"v":0.032833,"d":"0.03"},0,"-inf","-inf",1,1,"down","no"]
[152139,0,"chr4","+",74125438,74242197,"ENST00000433372",8,1407,"ENSG00000163738","MTHFD2L","GO:0000105(histidine biosynthetic process);GO:0003824(catalytic activity);GO:0004477(methenyltetrahydrofolate cyclohydrolase activity);GO:0004487(methylenetetrahydrofolate dehydrogenase (NAD+) activity);GO:0004488(methylenetetrahydrofolate dehydrogenase (NADP+) activity);GO:0005739(mitochondrion);GO:0005743(mitochondrial inner membrane);GO:0005759(mitochondrial matrix);GO:0006164(purine nucleotide biosynthetic process);GO:0006730(one-carbon metabolic process);GO:0008152(metabolic process);GO:0008652(cellular amino acid biosynthetic process);GO:0009086(methionine biosynthetic process);GO:0009256(10-formyltetrahydrofolate metabolic process);GO:0016020(membrane);GO:0016491(oxidoreductase activity);GO:0016787(hydrolase activity);GO:0035999(tetrahydrofolate interconversion);GO:0046653(tetrahydrofolate metabolic process);GO:0046655(folic acid metabolic process);GO:0055114(oxidation-reduction process)","00670(One carbon pool by folate)","K13403","3.5.4.9;EC:1.5.1.15","methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2 like [Source:HGNC Symbol;Acc:HGNC:31865]",0,0,0,0,0,0,1,0,1,1,"no","no"]
[191213,0,"chr8","+",96493813,96537343,"ENST00000520233",2,563,"ENSG00000169439","SDC2","GO:0001523(retinoid metabolic process);GO:0005515(protein binding);GO:0005788(endoplasmic reticulum lumen);GO:0005796(Golgi lumen);GO:0005886(plasma membrane);GO:0006024(glycosaminoglycan biosynthetic process);GO:0006027(glycosaminoglycan catabolic process);GO:0007399(nervous system development);GO:0008150(biological_process);GO:0009986(cell surface);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016477(cell migration);GO:0030154(cell differentiation);GO:0030165(PDZ domain binding);GO:0042802(identical protein binding);GO:0043202(lysosomal lumen);GO:0043687(post-translational protein modification);GO:0044267(cellular protein metabolic process);GO:0048013(ephrin receptor signaling pathway);GO:0048813(dendrite morphogenesis);GO:0048814(regulation of dendrite morphogenesis);GO:0050900(leukocyte migration);GO:0062023(collagen-containing extracellular matrix)","04514(Cell adhesion molecules (CAMs));05144(Malaria);05205(Proteoglycans in cancer);05418(Fluid shear stress and atherosclerosis)","K16336","NA","syndecan 2 [Source:HGNC Symbol;Acc:HGNC:10659]",0,0,{"v":1.663103,"d":"1.66"},0,0,0,"inf","inf",1,1,"up","no"]
[157484,0,"chr5","+",7901067,7906025,"ENST00000509379",3,455,"ENSG00000124275","MTRR","GO:0000096(sulfur amino acid metabolic process);GO:0003958(NADPH-hemoprotein reductase activity);GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0006306(DNA methylation);GO:0006555(methionine metabolic process);GO:0008652(cellular amino acid biosynthetic process);GO:0009086(methionine biosynthetic process);GO:0009235(cobalamin metabolic process);GO:0010181(FMN binding);GO:0016491(oxidoreductase activity);GO:0016723(oxidoreductase activity, oxidizing metal ions, NAD or NADP as acceptor);GO:0030586([methionine synthase] reductase activity);GO:0032259(methylation);GO:0033353(S-adenosylmethionine cycle);GO:0043418(homocysteine catabolic process);GO:0046655(folic acid metabolic process);GO:0050444(aquacobalamin reductase (NADPH) activity);GO:0050660(flavin adenine dinucleotide binding);GO:0050661(NADP binding);GO:0050667(homocysteine metabolic process);GO:0055114(oxidation-reduction process);GO:0070402(NADPH binding);GO:0071949(FAD binding);GO:1904042(negative regulation of cystathionine beta-synthase activity)","NA","K00597","EC:1.16.1.8","5-methyltetrahydrofolate-homocysteine methyltransferase reductase [Source:HGNC Symbol;Acc:HGNC:7473]",0,0,0,0,0,0,1,0,1,1,"no","no"]
[198913,0,"chr9","+",122939420,122940333,"ENST00000566531",1,914,"ENSG00000261094","AC007066","NA","NA","NA","NA","novel transcript, overlapping RABGAP1",{"v":0.406143,"d":"0.41"},{"v":0.465439,"d":"0.47"},{"v":0.615134,"d":"0.62"},{"v":0.286144,"d":"0.29"},{"v":0.106068,"d":"0.11"},{"v":0.097028,"d":"0.10"},{"v":3.03882756929115,"d":"3.04"},{"v":1.60351481504244,"d":"1.60"},1,1,"up","no"]
[160708,0,"chr5","-",87408038,87412871,"ENST00000510020",5,582,"ENSG00000134480","CCNH","GO:0000079(regulation of cyclin-dependent protein serine/threonine kinase activity);GO:0000082(G1/S transition of mitotic cell cycle);GO:0000086(G2/M transition of mitotic cell cycle);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005675(transcription factor TFIIH holo complex);GO:0006283(transcription-coupled nucleotide-excision repair);GO:0006294(nucleotide-excision repair, preincision complex assembly);GO:0006351(transcription, DNA-templated);GO:0006357(regulation of transcription by RNA polymerase II);GO:0006361(transcription initiation from RNA polymerase I promoter);GO:0006362(transcription elongation from RNA polymerase I promoter);GO:0006363(termination of RNA polymerase I transcription);GO:0006366(transcription by RNA polymerase II);GO:0006367(transcription initiation from RNA polymerase II promoter);GO:0006368(transcription elongation from RNA polymerase II promoter);GO:0006370(7-methylguanosine mRNA capping);GO:0006468(protein phosphorylation);GO:0007049(cell cycle);GO:0008094(DNA-dependent ATPase activity);GO:0008353(RNA polymerase II CTD heptapeptide repeat kinase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0016538(cyclin-dependent protein serine/threonine kinase regulator activity);GO:0019907(cyclin-dependent protein kinase activating kinase holoenzyme complex);GO:0045944(positive regulation of transcription by RNA polymerase II);GO:0050821(protein stabilization);GO:0070985(transcription factor TFIIK complex)","03022(Basal transcription factors);03420(Nucleotide excision repair);04110(Cell cycle)","NA","NA","cyclin H [Source:HGNC Symbol;Acc:HGNC:1594]",{"v":0.040849,"d":"0.04"},0,{"v":0.011111,"d":"0.01"},{"v":0.186042,"d":"0.19"},{"v":0.648711,"d":"0.65"},0,{"v":0.0622459577863152,"d":"0.06"},{"v":-4.00587603726848,"d":"-4.01"},1,1,"down","no"]
[44349,0,"chr12","-",56317348,56318574,"ENST00000553230",2,634,"ENSG00000135473","PAN2","GO:0000175(3'-5'-exoribonuclease activity);GO:0000288(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay);GO:0000289(nuclear-transcribed mRNA poly(A) tail shortening);GO:0000932(P-body);GO:0003676(nucleic acid binding);GO:0004518(nuclease activity);GO:0004527(exonuclease activity);GO:0004535(poly(A)-specific ribonuclease activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0006397(mRNA processing);GO:0010606(positive regulation of cytoplasmic mRNA processing body assembly);GO:0016787(hydrolase activity);GO:0031251(PAN complex);GO:0046872(metal ion binding);GO:0090305(nucleic acid phosphodiester bond hydrolysis);GO:0090503(RNA phosphodiester bond hydrolysis, exonucleolytic)","03018(RNA degradation)","K12571","EC:3.1.13.4","poly(A) specific ribonuclease subunit PAN2 [Source:HGNC Symbol;Acc:HGNC:20074]",{"v":0.215223,"d":"0.22"},{"v":0.552381,"d":"0.55"},{"v":0.389522,"d":"0.39"},{"v":0.469117,"d":"0.47"},{"v":0.307662,"d":"0.31"},{"v":0.159108,"d":"0.16"},{"v":1.23639499213046,"d":"1.24"},{"v":0.306139715857478,"d":"0.31"},1,1,"up","no"]
[18119,0,"chr1","+",243418017,243476364,"ENST00000463042",3,626,"ENSG00000054282","SDCCAG8","GO:0000086(G2/M transition of mitotic cell cycle);GO:0001764(neuron migration);GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0005813(centrosome);GO:0005814(centriole);GO:0005829(cytosol);GO:0005856(cytoskeleton);GO:0005911(cell-cell junction);GO:0007098(centrosome cycle);GO:0010389(regulation of G2/M transition of mitotic cell cycle);GO:0030010(establishment of cell polarity);GO:0030054(cell junction);GO:0031023(microtubule organizing center organization);GO:0034451(centriolar satellite);GO:0035148(tube formation);GO:0097711(ciliary basal body-plasma membrane docking);GO:1902017(regulation of cilium assembly)","NA","K16488","NA","serologically defined colon cancer antigen 8 [Source:HGNC Symbol;Acc:HGNC:10671]",{"v":0.067078,"d":"0.07"},0,{"v":0.263921,"d":"0.26"},{"v":0.033585,"d":"0.03"},{"v":0.148696,"d":"0.15"},{"v":0.298498,"d":"0.30"},{"v":0.688463930412934,"d":"0.69"},{"v":-0.538547023355764,"d":"-0.54"},1,1,"down","no"]
[18039,0,"chr1","+",241848951,241853481,"ENST00000450748",5,607,"ENSG00000174371","EXO1","GO:0002376(immune system process);GO:0002455(humoral immune response mediated by circulating immunoglobulin);GO:0003677(DNA binding);GO:0003682(chromatin binding);GO:0003824(catalytic activity);GO:0004518(nuclease activity);GO:0004519(endonuclease activity);GO:0004523(RNA-DNA hybrid ribonuclease activity);GO:0004527(exonuclease activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005886(plasma membrane);GO:0006260(DNA replication);GO:0006281(DNA repair);GO:0006298(mismatch repair);GO:0006310(DNA recombination);GO:0006974(cellular response to DNA damage stimulus);GO:0008409(5'-3' exonuclease activity);GO:0016446(somatic hypermutation of immunoglobulin genes);GO:0016604(nuclear body);GO:0016787(hydrolase activity);GO:0016788(hydrolase activity, acting on ester bonds);GO:0017108(5'-flap endonuclease activity);GO:0035312(5'-3' exodeoxyribonuclease activity);GO:0045145(single-stranded DNA 5'-3' exodeoxyribonuclease activity);GO:0045190(isotype switching);GO:0046872(metal ion binding);GO:0048256(flap endonuclease activity);GO:0051321(meiotic cell cycle);GO:0051908(double-stranded DNA 5'-3' exodeoxyribonuclease activity);GO:0090305(nucleic acid phosphodiester bond hydrolysis);GO:0090502(RNA phosphodiester bond hydrolysis, endonucleolytic);GO:0090656(t-circle formation);GO:1901796(regulation of signal transduction by p53 class mediator)","03430(Mismatch repair)","K10746","EC:3.1.-.-","exonuclease 1 [Source:HGNC Symbol;Acc:HGNC:3511]",0,0,0,0,0,0,1,0,1,1,"no","no"]
[171364,0,"chr6","-",53514207,53522779,"ENST00000505294",5,847,"ENSG00000001084","GCLC","GO:0000166(nucleotide binding);GO:0000287(magnesium ion binding);GO:0003824(catalytic activity);GO:0004357(glutamate-cysteine ligase activity);GO:0005524(ATP binding);GO:0005829(cytosol);GO:0006534(cysteine metabolic process);GO:0006536(glutamate metabolic process);GO:0006749(glutathione metabolic process);GO:0006750(glutathione biosynthetic process);GO:0006979(response to oxidative stress);GO:0007568(aging);GO:0007584(response to nutrient);GO:0008637(apoptotic mitochondrial changes);GO:0009408(response to heat);GO:0009410(response to xenobiotic stimulus);GO:0009725(response to hormone);GO:0014823(response to activity);GO:0016595(glutamate binding);GO:0016874(ligase activity);GO:0017109(glutamate-cysteine ligase complex);GO:0019852(L-ascorbic acid metabolic process);GO:0031397(negative regulation of protein ubiquitination);GO:0032436(positive regulation of proteasomal ubiquitin-dependent protein catabolic process);GO:0032869(cellular response to insulin stimulus);GO:0035729(cellular response to hepatocyte growth factor stimulus);GO:0043066(negative regulation of apoptotic process);GO:0043524(negative regulation of neuron apoptotic process);GO:0043531(ADP binding);GO:0044344(cellular response to fibroblast growth factor stimulus);GO:0044752(response to human chorionic gonadotropin);GO:0045454(cell redox homeostasis);GO:0045892(negative regulation of transcription, DNA-templated);GO:0046685(response to arsenic-containing substance);GO:0046686(response to cadmium ion);GO:0046982(protein heterodimerization activity);GO:0050662(coenzyme binding);GO:0050880(regulation of blood vessel size);GO:0051409(response to nitrosative stress);GO:0051900(regulation of mitochondrial depolarization);GO:0070555(response to interleukin-1);GO:0071260(cellular response to mechanical stimulus);GO:0071333(cellular response to glucose stimulus);GO:0071372(cellular response to follicle-stimulating hormone stimulus);GO:0097069(cellular response to thyroxine stimulus);GO:2000490(negative regulation of hepatic stellate cell activation);GO:2001237(negative regulation of extrinsic apoptotic signaling pathway)","00270(Cysteine and methionine metabolism);00480(Glutathione metabolism);04216(Ferroptosis)","NA","NA","glutamate-cysteine ligase catalytic subunit [Source:HGNC Symbol;Acc:HGNC:4311]",{"v":0.201017,"d":"0.20"},{"v":0.045469,"d":"0.05"},{"v":0.000438,"d":"0.00"},0,{"v":0.023587,"d":"0.02"},{"v":0.304666,"d":"0.30"},{"v":0.752236841704417,"d":"0.75"},{"v":-0.410741129053329,"d":"-0.41"},1,1,"down","no"]
[188533,0,"chr8","+",38820332,38850775,"ENST00000518809",12,4116,"ENSG00000147526","TACC1","GO:0000226(microtubule cytoskeleton organization);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005815(microtubule organizing center);GO:0005856(cytoskeleton);GO:0007049(cell cycle);GO:0007052(mitotic spindle organization);GO:0008283(cell population proliferation);GO:0016020(membrane);GO:0021987(cerebral cortex development);GO:0030496(midbody);GO:0051301(cell division)","NA","K14281","NA","transforming acidic coiled-coil containing protein 1 [Source:HGNC Symbol;Acc:HGNC:11522]",{"v":0.004717,"d":"0.00"},{"v":0.008907,"d":"0.01"},{"v":9.755139,"d":"9.76"},0,0,0,"inf","inf",1,1,"up","no"]
[387,0,"chr1","-",1336412,1339422,"ENST00000632445",6,785,"ENSG00000107404","DVL1","GO:0001505(regulation of neurotransmitter levels);GO:0001932(regulation of protein phosphorylation);GO:0001933(negative regulation of protein phosphorylation);GO:0001934(positive regulation of protein phosphorylation);GO:0005109(frizzled binding);GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005874(microtubule);GO:0005886(plasma membrane);GO:0006366(transcription by RNA polymerase II);GO:0006469(negative regulation of protein kinase activity);GO:0007269(neurotransmitter secretion);GO:0007275(multicellular organism development);GO:0007409(axonogenesis);GO:0007411(axon guidance);GO:0007528(neuromuscular junction development);GO:0008013(beta-catenin binding);GO:0010976(positive regulation of neuron projection development);GO:0014069(postsynaptic density);GO:0015630(microtubule cytoskeleton);GO:0016020(membrane);GO:0016055(Wnt signaling pathway);GO:0016328(lateral plasma membrane);GO:0019899(enzyme binding);GO:0019901(protein kinase binding);GO:0021915(neural tube development);GO:0022007(convergent extension involved in neural plate elongation);GO:0030136(clathrin-coated vesicle);GO:0030424(axon);GO:0030425(dendrite);GO:0030426(growth cone);GO:0031122(cytoplasmic microtubule organization);GO:0031410(cytoplasmic vesicle);GO:0032091(negative regulation of protein binding);GO:0032436(positive regulation of proteasomal ubiquitin-dependent protein catabolic process);GO:0034504(protein localization to nucleus);GO:0035176(social behavior);GO:0035372(protein localization to microtubule);GO:0035556(intracellular signal transduction);GO:0035567(non-canonical Wnt signaling pathway);GO:0042802(identical protein binding);GO:0043005(neuron projection);GO:0043025(neuronal cell body);GO:0043113(receptor clustering);GO:0043197(dendritic spine);GO:0045202(synapse);GO:0045893(positive regulation of transcription, DNA-templated);GO:0048365(Rac GTPase binding);GO:0048668(collateral sprouting);GO:0048675(axon extension);GO:0048813(dendrite morphogenesis);GO:0050808(synapse organization);GO:0050821(protein stabilization);GO:0060029(convergent extension involved in organogenesis);GO:0060070(canonical Wnt signaling pathway);GO:0060071(Wnt signaling pathway, planar cell polarity pathway);GO:0060134(prepulse inhibition);GO:0060997(dendritic spine morphogenesis);GO:0071340(skeletal muscle acetylcholine-gated channel clustering);GO:0090090(negative regulation of canonical Wnt signaling pathway);GO:0090103(cochlea morphogenesis);GO:0090179(planar cell polarity pathway involved in neural tube closure);GO:0098685(Schaffer collateral - CA1 synapse);GO:0098793(presynapse);GO:0098978(glutamatergic synapse);GO:0099054(presynapse assembly);GO:0099173(postsynapse organization);GO:0150012(positive regulation of neuron projection arborization);GO:1903827(regulation of cellular protein localization);GO:1904886(beta-catenin destruction complex disassembly);GO:1905386(positive regulation of protein localization to presynapse);GO:1990909(Wnt signalosome);GO:2000300(regulation of synaptic vesicle exocytosis);GO:2000463(positive regulation of excitatory postsynaptic potential)","04150(mTOR signaling pathway);04310(Wnt signaling pathway);04330(Notch signaling pathway);04390(Hippo signaling pathway);04550(Signaling pathways regulating pluripotency of stem cells);04916(Melanogenesis);04934(Cushing syndrome);05165(Human papillomavirus infection);05200(Pathways in cancer);05217(Basal cell carcinoma);05224(Breast cancer);05225(Hepatocellular carcinoma);05226(Gastric cancer)","K02353","NA","dishevelled segment polarity protein 1 [Source:HGNC Symbol;Acc:HGNC:3084]",{"v":0.503703,"d":"0.50"},{"v":0.202915,"d":"0.20"},{"v":0.087258,"d":"0.09"},{"v":0.114726,"d":"0.11"},{"v":0.123788,"d":"0.12"},{"v":0.039571,"d":"0.04"},{"v":2.85479619540788,"d":"2.85"},{"v":1.5133877549158,"d":"1.51"},1,1,"up","no"]
[189022,0,"chr8","+",47728720,47729704,"ENST00000518711",2,621,"ENSG00000164808","SPIDR","GO:0000228(nuclear chromosome);GO:0000724(double-strand break repair via homologous recombination);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0006281(DNA repair);GO:0006310(DNA recombination);GO:0006974(cellular response to DNA damage stimulus);GO:0010569(regulation of double-strand break repair via homologous recombination);GO:0031334(positive regulation of protein complex assembly);GO:0070202(regulation of establishment of protein localization to chromosome);GO:0071479(cellular response to ionizing radiation);GO:0072711(cellular response to hydroxyurea);GO:0072757(cellular response to camptothecin);GO:2000781(positive regulation of double-strand break repair)","NA","K22806","NA","scaffold protein involved in DNA repair [Source:HGNC Symbol;Acc:HGNC:28971]",{"v":0.687859,"d":"0.69"},{"v":0.636454,"d":"0.64"},{"v":0.601648,"d":"0.60"},{"v":0.284908,"d":"0.28"},{"v":0.164777,"d":"0.16"},{"v":0.136678,"d":"0.14"},{"v":3.28458821583217,"d":"3.28"},{"v":1.71571251325241,"d":"1.72"},1,1,"up","no"]
[105793,0,"chr19","+",47778701,47781556,"ENST00000595615",5,535,"ENSG00000178980","SELENOW","GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0010269(response to selenium ion);GO:0016209(antioxidant activity);GO:0098869(cellular oxidant detoxification)","NA","NA","NA","selenoprotein W [Source:HGNC Symbol;Acc:HGNC:10752]",{"v":0.406989,"d":"0.41"},{"v":0.001879,"d":"0.00"},{"v":0.539794,"d":"0.54"},{"v":0.00148,"d":"0.00"},{"v":0.00147,"d":"0.00"},{"v":0.275183,"d":"0.28"},{"v":3.41082144154056,"d":"3.41"},{"v":1.77011923101502,"d":"1.77"},1,1,"up","no"]
[182967,0,"chr7","-",110962308,111561924,"ENST00000447215",5,1164,"ENSG00000184903","IMMP2L","GO:0001541(ovarian follicle development);GO:0005739(mitochondrion);GO:0005743(mitochondrial inner membrane);GO:0006465(signal peptide processing);GO:0006508(proteolysis);GO:0006627(protein processing involved in protein targeting to mitochondrion);GO:0006801(superoxide metabolic process);GO:0006974(cellular response to DNA damage stimulus);GO:0007283(spermatogenesis);GO:0007420(brain development);GO:0008015(blood circulation);GO:0008233(peptidase activity);GO:0008236(serine-type peptidase activity);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016787(hydrolase activity);GO:0022904(respiratory electron transport chain);GO:0030728(ovulation);GO:0033108(mitochondrial respiratory chain complex assembly);GO:0042720(mitochondrial inner membrane peptidase complex);GO:0061300(cerebellum vasculature development)","03060(Protein export)","K09648","EC:3.4.21.-","inner mitochondrial membrane peptidase subunit 2 [Source:HGNC Symbol;Acc:HGNC:14598]",0,0,0,0,0,0,1,0,1,1,"no","no"]
[102285,0,"chr19","+",34734155,34739620,"ENST00000599244",4,499,"ENSG00000197841","ZNF181","GO:0000981(DNA-binding transcription factor activity, RNA polymerase II-specific);GO:0003676(nucleic acid binding);GO:0003677(DNA binding);GO:0005622(intracellular);GO:0005634(nucleus);GO:0006355(regulation of transcription, DNA-templated);GO:0006357(regulation of transcription by RNA polymerase II);GO:0046872(metal ion binding)","05168(Herpes simplex virus 1 infection)","K09228","NA","zinc finger protein 181 [Source:HGNC Symbol;Acc:HGNC:12971]",{"v":0.701827,"d":"0.70"},{"v":1.143016,"d":"1.14"},{"v":0.766976,"d":"0.77"},{"v":1.476017,"d":"1.48"},{"v":1.077278,"d":"1.08"},{"v":0.179772,"d":"0.18"},{"v":0.955636652888495,"d":"0.96"},{"v":-0.0654659063020097,"d":"-0.07"},1,1,"down","no"]
[67655,0,"chr15","+",84422618,84425882,"ENST00000559866",4,1212,"ENSG00000259774","AC243562","NA","NA","NA","NA","novel transcript",{"v":0.197342,"d":"0.20"},0,0,{"v":0.127209,"d":"0.13"},0,{"v":0.044128,"d":"0.04"},{"v":1.15177690749809,"d":"1.15"},{"v":0.203861302184024,"d":"0.20"},1,1,"up","no"]
[81946,0,"chr17","+",16217237,16234140,"ENST00000489009",2,395,"ENSG00000108474","PIGL","GO:0000225(N-acetylglucosaminylphosphatidylinositol deacetylase activity);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0006506(GPI anchor biosynthetic process);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016254(preassembly of GPI anchor in ER membrane);GO:0016787(hydrolase activity)","00563(Glycosylphosphatidylinositol (GPI)-anchor biosynthesis)","K03434","EC:3.5.1.89","phosphatidylinositol glycan anchor biosynthesis class L [Source:HGNC Symbol;Acc:HGNC:8966]",{"v":0.029922,"d":"0.03"},{"v":0.012262,"d":"0.01"},{"v":0.008274,"d":"0.01"},{"v":0.602088,"d":"0.60"},{"v":0.000666,"d":"0.00"},{"v":0.003245,"d":"0.00"},{"v":0.0832641638022505,"d":"0.08"},{"v":-3.58616048444749,"d":"-3.59"},1,1,"down","no"]
[181299,0,"chr7","-",94585366,94656072,"ENST00000646119",12,1493,"ENSG00000127990","SGCE","GO:0005509(calcium ion binding);GO:0005737(cytoplasm);GO:0005794(Golgi apparatus);GO:0005856(cytoskeleton);GO:0005886(plasma membrane);GO:0005887(integral component of plasma membrane);GO:0007160(cell-matrix adhesion);GO:0007517(muscle organ development);GO:0016010(dystrophin-associated glycoprotein complex);GO:0016012(sarcoglycan complex);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0030425(dendrite);GO:0032590(dendrite membrane);GO:0042383(sarcolemma);GO:0042995(cell projection)","NA","NA","NA","sarcoglycan epsilon [Source:HGNC Symbol;Acc:HGNC:10808]",0,{"v":0.107491,"d":"0.11"},0,0,0,0,"inf","inf",1,1,"up","no"]
[136664,0,"chr3","+",9902848,9916395,"ENST00000434065",14,2541,"ENSG00000163701","IL17RE","GO:0005515(protein binding);GO:0005576(extracellular region);GO:0005737(cytoplasm);GO:0005886(plasma membrane);GO:0006954(inflammatory response);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0019221(cytokine-mediated signaling pathway);GO:0030368(interleukin-17 receptor activity);GO:0097400(interleukin-17-mediated signaling pathway)","04060(Cytokine-cytokine receptor interaction);04657(IL-17 signaling pathway)","K05168","NA","interleukin 17 receptor E [Source:HGNC Symbol;Acc:HGNC:18439]",0,0,0,{"v":0.307615,"d":"0.31"},0,0,"-inf","-inf",1,1,"down","no"]
[193642,0,"chr8","-",143837756,143837816,"ENST00000613182",1,61,"ENSG00000284142","MIR6845","NA","NA","NA","NA","microRNA 6845 [Source:HGNC Symbol;Acc:HGNC:49956]",{"v":0.067795,"d":"0.07"},{"v":0.096862,"d":"0.10"},{"v":0.099495,"d":"0.10"},{"v":0.043471,"d":"0.04"},{"v":0.095088,"d":"0.10"},{"v":0.055404,"d":"0.06"},{"v":1.36186798513118,"d":"1.36"},{"v":0.445586860158058,"d":"0.45"},1,1,"up","no"]
[207119,0,"chrX","+",153774929,153776399,"ENST00000482654",5,717,"ENSG00000198753","PLXNB3","GO:0001938(positive regulation of endothelial cell proliferation);GO:0002116(semaphorin receptor complex);GO:0005515(protein binding);GO:0005886(plasma membrane);GO:0005887(integral component of plasma membrane);GO:0007156(homophilic cell adhesion via plasma membrane adhesion molecules);GO:0007162(negative regulation of cell adhesion);GO:0007165(signal transduction);GO:0007399(nervous system development);GO:0008360(regulation of cell shape);GO:0009986(cell surface);GO:0010593(negative regulation of lamellipodium assembly);GO:0010976(positive regulation of neuron projection development);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0017154(semaphorin receptor activity);GO:0019904(protein domain specific binding);GO:0030334(regulation of cell migration);GO:0030336(negative regulation of cell migration);GO:0034260(negative regulation of GTPase activity);GO:0043087(regulation of GTPase activity);GO:0050772(positive regulation of axonogenesis);GO:0050918(positive chemotaxis);GO:0051022(Rho GDP-dissociation inhibitor binding);GO:0060326(cell chemotaxis);GO:0071526(semaphorin-plexin signaling pathway);GO:0098632(cell-cell adhesion mediator activity);GO:1902287(semaphorin-plexin signaling pathway involved in axon guidance)","04360(Axon guidance)","K06821","NA","plexin B3 [Source:HGNC Symbol;Acc:HGNC:9105]",0,0,0,0,0,0,1,0,1,1,"no","no"]
[13628,0,"chr1","+",165895585,165907871,"ENST00000470820",4,1083,"ENSG00000143179","UCK2","GO:0000166(nucleotide binding);GO:0004849(uridine kinase activity);GO:0005524(ATP binding);GO:0005575(cellular_component);GO:0005829(cytosol);GO:0006238(CMP salvage);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0016740(transferase activity);GO:0019206(nucleoside kinase activity);GO:0043097(pyrimidine nucleoside salvage);GO:0044206(UMP salvage);GO:0044211(CTP salvage)","00240(Pyrimidine metabolism);00983(Drug metabolism - other enzymes)","K00876","EC:2.7.1.48","uridine-cytidine kinase 2 [Source:HGNC Symbol;Acc:HGNC:12562]",{"v":0.010814,"d":"0.01"},{"v":0.094647,"d":"0.09"},{"v":0.019138,"d":"0.02"},{"v":0.041161,"d":"0.04"},{"v":0.017788,"d":"0.02"},{"v":0.136014,"d":"0.14"},{"v":0.639090494093751,"d":"0.64"},{"v":-0.645907866161663,"d":"-0.65"},1,1,"down","no"]
[136037,0,"chr22","-",50569084,50578455,"ENST00000395650",19,2662,"ENSG00000205560","CPT1B","GO:0004095(carnitine O-palmitoyltransferase activity);GO:0005515(protein binding);GO:0005739(mitochondrion);GO:0005741(mitochondrial outer membrane);GO:0006629(lipid metabolic process);GO:0006631(fatty acid metabolic process);GO:0006635(fatty acid beta-oxidation);GO:0006853(carnitine shuttle);GO:0009437(carnitine metabolic process);GO:0015909(long-chain fatty acid transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016740(transferase activity);GO:0016746(transferase activity, transferring acyl groups);GO:0043231(intracellular membrane-bounded organelle)","00071(Fatty acid degradation);03320(PPAR signaling pathway);04152(AMPK signaling pathway);04714(Thermogenesis);04920(Adipocytokine signaling pathway);04922(Glucagon signaling pathway);04931(Insulin resistance)","K19523","EC:2.3.1.21","carnitine palmitoyltransferase 1B [Source:HGNC Symbol;Acc:HGNC:2329]",{"v":0.021109,"d":"0.02"},{"v":0.001062,"d":"0.00"},0,0,0,0,"inf","inf",1,1,"up","no"]
[81348,0,"chr17","+",8329583,8329719,"ENST00000390904",1,137,"ENSG00000212206","RF00265","NA","NA","NA","NA","NA",{"v":0.109775,"d":"0.11"},0,0,0,0,0,"inf","inf",1,1,"up","no"]
[153076,0,"chr4","-",86888160,86892422,"ENST00000504371",4,585,"ENSG00000163633","C4orf36","NA","NA","NA","NA","chromosome 4 open reading frame 36 [Source:HGNC Symbol;Acc:HGNC:28386]",0,0,0,0,{"v":0.098294,"d":"0.10"},0,"-inf","-inf",1,1,"down","no"]
[7682,0,"chr1","-",77955255,77960785,"ENST00000470287",4,726,"ENSG00000162613","FUBP1","GO:0003676(nucleic acid binding);GO:0003677(DNA binding);GO:0003697(single-stranded DNA binding);GO:0003700(DNA-binding transcription factor activity);GO:0003723(RNA binding);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0006355(regulation of transcription, DNA-templated);GO:0006366(transcription by RNA polymerase II);GO:0010628(positive regulation of gene expression)","NA","K13210","NA","far upstream element binding protein 1 [Source:HGNC Symbol;Acc:HGNC:4004]",{"v":0.294025,"d":"0.29"},{"v":0.248195,"d":"0.25"},{"v":0.001896,"d":"0.00"},{"v":0.410986,"d":"0.41"},{"v":0.110157,"d":"0.11"},{"v":0.124139,"d":"0.12"},{"v":0.843222033157596,"d":"0.84"},{"v":-0.24601553019888,"d":"-0.25"},1,1,"down","no"]
[144073,0,"chr3","-",129169569,129183910,"ENST00000500450",5,1516,"ENSG00000169714","CNBP","GO:0000122(negative regulation of transcription by RNA polymerase II);GO:0000977(RNA polymerase II regulatory region sequence-specific DNA binding);GO:0001227(DNA-binding transcription repressor activity, RNA polymerase II-specific);GO:0003676(nucleic acid binding);GO:0003677(DNA binding);GO:0003697(single-stranded DNA binding);GO:0003700(DNA-binding transcription factor activity);GO:0003723(RNA binding);GO:0003727(single-stranded RNA binding);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005783(endoplasmic reticulum);GO:0005829(cytosol);GO:0006355(regulation of transcription, DNA-templated);GO:0006695(cholesterol biosynthetic process);GO:0008270(zinc ion binding);GO:0008284(positive regulation of cell population proliferation);GO:0045893(positive regulation of transcription, DNA-templated);GO:0045944(positive regulation of transcription by RNA polymerase II);GO:0046872(metal ion binding)","NA","K09250","NA","CCHC-type zinc finger nucleic acid binding protein [Source:HGNC Symbol;Acc:HGNC:13164]",0,0,0,0,0,{"v":1.123123,"d":"1.12"},"-inf","-inf",1,1,"down","no"]
[119711,0,"chr2","+",178451436,178461390,"ENST00000409117",7,1531,"ENSG00000204311","PJVK","GO:0007605(sensory perception of sound);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0043025(neuronal cell body)","NA","K22147","NA","pejvakin [Source:HGNC Symbol;Acc:HGNC:29502]",0,{"v":0.330284,"d":"0.33"},0,0,0,0,"inf","inf",1,1,"up","no"]
[201389,0,"chrX","+",9408818,9409571,"ENST00000631993",1,754,"ENSG00000282299","AC073488","NA","NA","NA","NA","chromodomain protein, Y chromosome-like (CDYL) pseudogene",0,0,0,0,0,0,1,0,1,1,"no","no"]
[162083,0,"chr5","+",122936733,123029354,"ENST00000502387",6,500,"ENSG00000064652","SNX24","GO:0008289(lipid binding);GO:0010314(phosphatidylinositol-5-phosphate binding);GO:0015031(protein transport);GO:0016020(membrane);GO:0030659(cytoplasmic vesicle membrane);GO:0031410(cytoplasmic vesicle);GO:0032266(phosphatidylinositol-3-phosphate binding);GO:0035091(phosphatidylinositol binding);GO:0070273(phosphatidylinositol-4-phosphate binding)","NA","K17941","NA","sorting nexin 24 [Source:HGNC Symbol;Acc:HGNC:21533]",{"v":0.304807,"d":"0.30"},{"v":0.38691,"d":"0.39"},{"v":0.000427,"d":"0.00"},{"v":0.285973,"d":"0.29"},{"v":0.455514,"d":"0.46"},0,{"v":0.933453991775985,"d":"0.93"},{"v":-0.0993491784587782,"d":"-0.10"},1,1,"down","no"]
[78868,0,"chr16","+",89147567,89154586,"ENST00000393145",1,7020,"ENSG00000176715","ACSF3","GO:0000166(nucleotide binding);GO:0003824(catalytic activity);GO:0005524(ATP binding);GO:0005739(mitochondrion);GO:0005759(mitochondrial matrix);GO:0006629(lipid metabolic process);GO:0006631(fatty acid metabolic process);GO:0006633(fatty acid biosynthetic process);GO:0016874(ligase activity);GO:0016878(acid-thiol ligase activity);GO:0031957(very long-chain fatty acid-CoA ligase activity);GO:0035338(long-chain fatty-acyl-CoA biosynthetic process);GO:0090409(malonyl-CoA synthetase activity);GO:0090410(malonate catabolic process)","00280(Valine, leucine and isoleucine degradation)","K18660","EC:6.2.1.-","acyl-CoA synthetase family member 3 [Source:HGNC Symbol;Acc:HGNC:27288]",{"v":0.026018,"d":"0.03"},{"v":0.014895,"d":"0.01"},{"v":0.082022,"d":"0.08"},{"v":0.035681,"d":"0.04"},{"v":0.00943,"d":"0.01"},{"v":0.081826,"d":"0.08"},{"v":0.968472549374887,"d":"0.97"},{"v":-0.046216937583843,"d":"-0.05"},1,1,"down","no"]
[101504,0,"chr19","-",20415305,20424956,"ENST00000596724",3,636,"ENSG00000231205","ZNF826P","NA","NA","NA","NA","zinc finger protein 826, pseudogene [Source:HGNC Symbol;Acc:HGNC:33875]",{"v":0.027627,"d":"0.03"},0,{"v":0.154113,"d":"0.15"},{"v":0.045248,"d":"0.05"},{"v":0.040783,"d":"0.04"},{"v":0.06972,"d":"0.07"},{"v":1.16686249205463,"d":"1.17"},{"v":0.22263455785803,"d":"0.22"},1,1,"up","no"]
[33764,0,"chr11","+",72080812,72096135,"ENST00000423494",5,1270,"ENSG00000184154","LRTOMT","GO:0005515(protein binding);GO:0005575(cellular_component);GO:0005737(cytoplasm);GO:0005783(endoplasmic reticulum);GO:0005886(plasma membrane);GO:0006584(catecholamine metabolic process);GO:0007605(sensory perception of sound);GO:0008168(methyltransferase activity);GO:0008171(O-methyltransferase activity);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016206(catechol O-methyltransferase activity);GO:0016740(transferase activity);GO:0032259(methylation);GO:0032502(developmental process);GO:0042135(neurotransmitter catabolic process);GO:0042417(dopamine metabolic process);GO:0042424(catecholamine catabolic process);GO:0060117(auditory receptor cell development);GO:0102084(L-dopa O-methyltransferase activity);GO:0102938(orcinol O-methyltransferase activity)","00140(Steroid hormone biosynthesis);00350(Tyrosine metabolism);04728(Dopaminergic synapse)","K00545","EC:2.1.1.6","leucine rich transmembrane and O-methyltransferase domain containing [Source:HGNC Symbol;Acc:HGNC:25033]",{"v":0.095534,"d":"0.10"},{"v":0.099533,"d":"0.10"},{"v":0.113555,"d":"0.11"},0,0,{"v":0.081545,"d":"0.08"},{"v":3.78468330369734,"d":"3.78"},{"v":1.92017258282634,"d":"1.92"},1,1,"up","no"]
[42739,0,"chr12","+",50103982,50106387,"ENST00000547964",5,573,"ENSG00000167588","GPD1","GO:0004367(glycerol-3-phosphate dehydrogenase [NAD+] activity);GO:0004368(glycerol-3-phosphate dehydrogenase (quinone) activity);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005975(carbohydrate metabolic process);GO:0006072(glycerol-3-phosphate metabolic process);GO:0006094(gluconeogenesis);GO:0006116(NADH oxidation);GO:0006127(glycerophosphate shuttle);GO:0006654(phosphatidic acid biosynthetic process);GO:0006734(NADH metabolic process);GO:0009331(glycerol-3-phosphate dehydrogenase complex);GO:0016491(oxidoreductase activity);GO:0016616(oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor);GO:0042803(protein homodimerization activity);GO:0045821(positive regulation of glycolytic process);GO:0046168(glycerol-3-phosphate catabolic process);GO:0046486(glycerolipid metabolic process);GO:0047952(glycerol-3-phosphate dehydrogenase [NAD(P)+] activity);GO:0051287(NAD binding);GO:0055114(oxidation-reduction process);GO:0070062(extracellular exosome);GO:0071320(cellular response to cAMP);GO:0071356(cellular response to tumor necrosis factor)","00564(Glycerophospholipid metabolism)","K00006","EC:1.1.1.8","glycerol-3-phosphate dehydrogenase 1 [Source:HGNC Symbol;Acc:HGNC:4455]",{"v":0.02942,"d":"0.03"},{"v":0.070994,"d":"0.07"},0,0,0,0,"inf","inf",1,1,"up","no"]
[164952,0,"chr5","+",159310933,159333182,"ENST00000521472",4,811,"ENSG00000249738","AC008691","NA","NA","NA","NA","novel transcript",0,0,0,0,0,{"v":0.048929,"d":"0.05"},"-inf","-inf",1,1,"down","no"]
[154432,0,"chr4","-",119408603,119421337,"ENST00000652280",6,2891,"ENSG00000283050","GTF2IP12","NA","NA","NA","NA","general transcription factor IIi pseudogene 12 [Source:HGNC Symbol;Acc:HGNC:51723]",0,0,0,0,{"v":0.035888,"d":"0.04"},0,"-inf","-inf",1,1,"down","no"]
[34687,0,"chr11","-",78423982,78429836,"ENST00000513207",4,1642,"ENSG00000251323","AP003086","NA","NA","NA","NA","novel transcript",0,{"v":0.022429,"d":"0.02"},{"v":0.027792,"d":"0.03"},0,{"v":0.063187,"d":"0.06"},0,{"v":0.794799563201291,"d":"0.79"},{"v":-0.331337015162769,"d":"-0.33"},1,1,"down","no"]
[164431,0,"chr5","+",150497778,150553714,"ENST00000523767",14,3449,"ENSG00000070614","NDST1","GO:0000139(Golgi membrane);GO:0003824(catalytic activity);GO:0005515(protein binding);GO:0005794(Golgi apparatus);GO:0006024(glycosaminoglycan biosynthetic process);GO:0006954(inflammatory response);GO:0008146(sulfotransferase activity);GO:0008152(metabolic process);GO:0015012(heparan sulfate proteoglycan biosynthetic process);GO:0015014(heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process);GO:0015016([heparan sulfate]-glucosamine N-sulfotransferase activity);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016740(transferase activity);GO:0016787(hydrolase activity);GO:0019213(deacetylase activity);GO:0030210(heparin biosynthetic process);GO:0034483(heparan sulfate sulfotransferase activity);GO:0042328(heparan sulfate N-acetylglucosaminyltransferase activity)","00534(Glycosaminoglycan biosynthesis - heparan sulfate / heparin)","K02576","2.8.2.-;EC:3.1.1.-","N-deacetylase and N-sulfotransferase 1 [Source:HGNC Symbol;Acc:HGNC:7680]",0,{"v":0.015814,"d":"0.02"},{"v":0.084284,"d":"0.08"},{"v":0.006096,"d":"0.01"},{"v":0.0143,"d":"0.01"},{"v":0.150459,"d":"0.15"},{"v":0.585865207339557,"d":"0.59"},{"v":-0.771359319440763,"d":"-0.77"},1,1,"down","no"]
[50677,0,"chr13","-",27437116,27450196,"ENST00000460973",5,785,"ENSG00000122033","MTIF3","GO:0003743(translation initiation factor activity);GO:0005515(protein binding);GO:0005739(mitochondrion);GO:0006412(translation);GO:0006413(translational initiation);GO:0008135(translation factor activity, RNA binding);GO:0032790(ribosome disassembly);GO:0043022(ribosome binding);GO:0043024(ribosomal small subunit binding);GO:0070124(mitochondrial translational initiation)","NA","K02520","NA","mitochondrial translational initiation factor 3 [Source:HGNC Symbol;Acc:HGNC:29788]",{"v":0.012831,"d":"0.01"},{"v":0.01846,"d":"0.02"},{"v":0.024531,"d":"0.02"},{"v":0.054816,"d":"0.05"},{"v":0.119832,"d":"0.12"},{"v":0.034331,"d":"0.03"},{"v":0.267117748673312,"d":"0.27"},{"v":-1.90445225567115,"d":"-1.90"},1,1,"down","no"]
[35603,0,"chr11","-",100684162,100687955,"ENST00000501397",2,1865,"ENSG00000248027","AP001351","NA","NA","NA","NA","novel transcript, antisense to ARHGAP42",{"v":0.04503,"d":"0.05"},{"v":0.023597,"d":"0.02"},{"v":0.047151,"d":"0.05"},{"v":0.037697,"d":"0.04"},0,0,{"v":3.07127888160862,"d":"3.07"},{"v":1.61883951942752,"d":"1.62"},1,1,"up","no"]
[121582,0,"chr2","+",210232692,210233976,"ENST00000623861",1,1285,"ENSG00000279317","AC006994","NA","NA","NA","NA","novel transcript",0,0,0,0,0,{"v":0.034507,"d":"0.03"},"-inf","-inf",1,1,"down","no"]
[184948,0,"chr7","-",143811390,143836706,"ENST00000468266",3,463,"ENSG00000253882","AC099548","NA","NA","NA","NA","family with sequence similarity 115, member C (FAM115C) pseudogene",0,{"v":0.105072,"d":"0.11"},0,0,0,0,"inf","inf",1,1,"up","no"]
[158775,0,"chr5","-",43543061,43557077,"ENST00000504075",3,501,"ENSG00000172239","PAIP1","GO:0003723(RNA binding);GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0006413(translational initiation);GO:0006417(regulation of translation);GO:0006446(regulation of translational initiation);GO:0008494(translation activator activity);GO:0045727(positive regulation of translation);GO:0048255(mRNA stabilization)","03013(RNA transport)","K14322","NA","poly(A) binding protein interacting protein 1 [Source:HGNC Symbol;Acc:HGNC:16945]",0,0,{"v":0.148574,"d":"0.15"},{"v":0.127997,"d":"0.13"},{"v":0.424001,"d":"0.42"},{"v":0.271307,"d":"0.27"},{"v":0.18046046118996,"d":"0.18"},{"v":-2.47024531701978,"d":"-2.47"},1,1,"down","no"]
[47679,0,"chr12","+",109052642,109072347,"ENST00000536393",5,476,"ENSG00000135093","USP30","GO:0000422(autophagy of mitochondrion);GO:0004197(cysteine-type endopeptidase activity);GO:0004843(thiol-dependent ubiquitin-specific protease activity);GO:0005739(mitochondrion);GO:0005741(mitochondrial outer membrane);GO:0006508(proteolysis);GO:0006511(ubiquitin-dependent protein catabolic process);GO:0008053(mitochondrial fusion);GO:0008233(peptidase activity);GO:0008234(cysteine-type peptidase activity);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016579(protein deubiquitination);GO:0016787(hydrolase activity);GO:0035871(protein K11-linked deubiquitination);GO:0036459(thiol-dependent ubiquitinyl hydrolase activity);GO:0044313(protein K6-linked deubiquitination);GO:1901525(negative regulation of mitophagy)","04137(Mitophagy - animal)","K11851","EC:3.4.19.12","ubiquitin specific peptidase 30 [Source:HGNC Symbol;Acc:HGNC:20065]",{"v":0.309098,"d":"0.31"},{"v":0.473775,"d":"0.47"},0,0,0,{"v":0.153231,"d":"0.15"},{"v":5.1091032493425,"d":"5.11"},{"v":2.35307009130803,"d":"2.35"},1,1,"up","no"]
[200986,0,"chr9","+",137605694,137614076,"ENST00000431925",5,555,"ENSG00000197070","ARRDC1","GO:0005515(protein binding);GO:0005886(plasma membrane);GO:0006511(ubiquitin-dependent protein catabolic process);GO:0006858(extracellular transport);GO:0015031(protein transport);GO:0016020(membrane);GO:0016567(protein ubiquitination);GO:0031410(cytoplasmic vesicle);GO:0031625(ubiquitin protein ligase binding);GO:0042802(identical protein binding);GO:0045746(negative regulation of Notch signaling pathway);GO:0070062(extracellular exosome);GO:0140112(extracellular vesicle biogenesis);GO:1903561(extracellular vesicle);GO:1990756(protein binding, bridging involved in substrate recognition for ubiquitination);GO:1990763(arrestin family protein binding)","NA","NA","NA","arrestin domain containing 1 [Source:HGNC Symbol;Acc:HGNC:28633]",0,0,{"v":0.003748,"d":"0.00"},0,0,{"v":0.016591,"d":"0.02"},{"v":0.225905611476101,"d":"0.23"},{"v":-2.14620798728963,"d":"-2.15"},1,1,"down","no"]
[195700,0,"chr9","+",36190937,36212059,"ENST00000242285",7,1152,"ENSG00000122705","CLTA","GO:0003674(molecular_function);GO:0005198(structural molecule activity);GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0005819(spindle);GO:0005829(cytosol);GO:0005856(cytoskeleton);GO:0005886(plasma membrane);GO:0005905(clathrin-coated pit);GO:0006886(intracellular protein transport);GO:0006897(endocytosis);GO:0007049(cell cycle);GO:0016020(membrane);GO:0016192(vesicle-mediated transport);GO:0019886(antigen processing and presentation of exogenous peptide antigen via MHC class II);GO:0030118(clathrin coat);GO:0030125(clathrin vesicle coat);GO:0030130(clathrin coat of trans-Golgi network vesicle);GO:0030132(clathrin coat of coated pit);GO:0030136(clathrin-coated vesicle);GO:0030659(cytoplasmic vesicle membrane);GO:0030672(synaptic vesicle membrane);GO:0031410(cytoplasmic vesicle);GO:0032050(clathrin heavy chain binding);GO:0032588(trans-Golgi network membrane);GO:0032802(low-density lipoprotein particle receptor catabolic process);GO:0034383(low-density lipoprotein particle clearance);GO:0036020(endolysosome membrane);GO:0042277(peptide binding);GO:0044877(protein-containing complex binding);GO:0045334(clathrin-coated endocytic vesicle);GO:0048268(clathrin coat assembly);GO:0051020(GTPase binding);GO:0051301(cell division);GO:0061024(membrane organization);GO:0071439(clathrin complex);GO:0072583(clathrin-dependent endocytosis);GO:0098835(presynaptic endocytic zone membrane);GO:0099631(postsynaptic endocytic zone cytoplasmic component)","04142(Lysosome);04144(Endocytosis);04721(Synaptic vesicle cycle);04961(Endocrine and other factor-regulated calcium reabsorption);05016(Huntington disease);05100(Bacterial invasion of epithelial cells)","NA","NA","clathrin light chain A [Source:HGNC Symbol;Acc:HGNC:2090]",0,0,{"v":0.038958,"d":"0.04"},0,0,0,"inf","inf",1,1,"up","no"]
[135189,0,"chr22","-",42086116,42087335,"ENST00000470753",2,475,"ENSG00000184983","NDUFA6","GO:0005739(mitochondrion);GO:0005743(mitochondrial inner membrane);GO:0005747(mitochondrial respiratory chain complex I);GO:0006120(mitochondrial electron transport, NADH to ubiquinone);GO:0006979(response to oxidative stress);GO:0008137(NADH dehydrogenase (ubiquinone) activity);GO:0016020(membrane);GO:0031966(mitochondrial membrane);GO:0032981(mitochondrial respiratory chain complex I assembly);GO:0055114(oxidation-reduction process);GO:0070469(respirasome)","00190(Oxidative phosphorylation);04714(Thermogenesis);04723(Retrograde endocannabinoid signaling);04932(Non-alcoholic fatty liver disease (NAFLD));05010(Alzheimer disease);05012(Parkinson disease);05016(Huntington disease)","K03950","NA","NADH:ubiquinone oxidoreductase subunit A6 [Source:HGNC Symbol;Acc:HGNC:7690]",{"v":0.190592,"d":"0.19"},{"v":0.918643,"d":"0.92"},{"v":0.719854,"d":"0.72"},{"v":0.047137,"d":"0.05"},{"v":0.047668,"d":"0.05"},{"v":0.313805,"d":"0.31"},{"v":4.47636866449671,"d":"4.48"},{"v":2.1623288585973,"d":"2.16"},1,1,"up","no"]
[62573,0,"chr15","-",35372256,35372364,"ENST00000585264",1,109,"ENSG00000265102","MIR3942","NA","NA","NA","NA","microRNA 3942 [Source:HGNC Symbol;Acc:HGNC:38976]",{"v":0.24043,"d":"0.24"},{"v":0.160352,"d":"0.16"},{"v":0.033829,"d":"0.03"},{"v":1.150457,"d":"1.15"},{"v":0.08101,"d":"0.08"},{"v":0.624635,"d":"0.62"},{"v":0.234152541185775,"d":"0.23"},{"v":-2.09447939963825,"d":"-2.09"},1,1,"down","no"]
[127158,0,"chr20","+",44933043,44937187,"ENST00000465761",3,801,"ENSG00000101104","PABPC1L","GO:0001556(oocyte maturation);GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0003730(mRNA 3'-UTR binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0006338(chromatin remodeling);GO:0006378(mRNA polyadenylation);GO:0008143(poly(A) binding);GO:0008266(poly(U) RNA binding);GO:0010494(cytoplasmic stress granule);GO:0048096(chromatin-mediated maintenance of transcription);GO:0051647(nucleus localization);GO:0070062(extracellular exosome);GO:1990904(ribonucleoprotein complex)","03013(RNA transport);03015(mRNA surveillance pathway);03018(RNA degradation)","K13126","NA","poly(A) binding protein cytoplasmic 1 like [Source:HGNC Symbol;Acc:HGNC:15797]",{"v":0.234811,"d":"0.23"},{"v":0.254026,"d":"0.25"},{"v":0.134374,"d":"0.13"},{"v":0.070493,"d":"0.07"},{"v":0.047624,"d":"0.05"},{"v":0.174839,"d":"0.17"},{"v":2.12731946094294,"d":"2.13"},{"v":1.08903670001731,"d":"1.09"},1,1,"up","no"]
[147805,0,"chr3","+",186842704,186858463,"ENST00000444204",4,4599,"ENSG00000181092","ADIPOQ","GO:0001666(response to hypoxia);GO:0001934(positive regulation of protein phosphorylation);GO:0005102(signaling receptor binding);GO:0005125(cytokine activity);GO:0005179(hormone activity);GO:0005201(extracellular matrix structural constituent);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0005581(collagen trimer);GO:0005615(extracellular space);GO:0005783(endoplasmic reticulum);GO:0006006(glucose metabolic process);GO:0006091(generation of precursor metabolites and energy);GO:0006635(fatty acid beta-oxidation);GO:0007584(response to nutrient);GO:0007623(circadian rhythm);GO:0009617(response to bacterium);GO:0009744(response to sucrose);GO:0009749(response to glucose);GO:0009967(positive regulation of signal transduction);GO:0009986(cell surface);GO:0010469(regulation of signaling receptor activity);GO:0010642(negative regulation of platelet-derived growth factor receptor signaling pathway);GO:0010739(positive regulation of protein kinase A signaling);GO:0010745(negative regulation of macrophage derived foam cell differentiation);GO:0010804(negative regulation of tumor necrosis factor-mediated signaling pathway);GO:0010875(positive regulation of cholesterol efflux);GO:0010906(regulation of glucose metabolic process);GO:0014823(response to activity);GO:0019395(fatty acid oxidation);GO:0030336(negative regulation of cell migration);GO:0030853(negative regulation of granulocyte differentiation);GO:0031667(response to nutrient levels);GO:0031953(negative regulation of protein autophosphorylation);GO:0032270(positive regulation of cellular protein metabolic process);GO:0032720(negative regulation of tumor necrosis factor production);GO:0032757(positive regulation of interleukin-8 production);GO:0032869(cellular response to insulin stimulus);GO:0032991(protein-containing complex);GO:0033034(positive regulation of myeloid cell apoptotic process);GO:0033691(sialic acid binding);GO:0034115(negative regulation of heterotypic cell-cell adhesion);GO:0034383(low-density lipoprotein particle clearance);GO:0034612(response to tumor necrosis factor);GO:0035690(cellular response to drug);GO:0042304(regulation of fatty acid biosynthetic process);GO:0042493(response to drug);GO:0042593(glucose homeostasis);GO:0042802(identical protein binding);GO:0042803(protein homodimerization activity);GO:0043123(positive regulation of I-kappaB kinase/NF-kappaB signaling);GO:0043124(negative regulation of I-kappaB kinase/NF-kappaB signaling);GO:0043407(negative regulation of MAP kinase activity);GO:0045471(response to ethanol);GO:0045599(negative regulation of fat cell differentiation);GO:0045650(negative regulation of macrophage differentiation);GO:0045715(negative regulation of low-density lipoprotein particle receptor biosynthetic process);GO:0045721(negative regulation of gluconeogenesis);GO:0045776(negative regulation of blood pressure);GO:0045860(positive regulation of protein kinase activity);GO:0045892(negative regulation of transcription, DNA-templated);GO:0045923(positive regulation of fatty acid metabolic process);GO:0046326(positive regulation of glucose import);GO:0046888(negative regulation of hormone secretion);GO:0050728(negative regulation of inflammatory response);GO:0050731(positive regulation of peptidyl-tyrosine phosphorylation);GO:0050765(negative regulation of phagocytosis);GO:0050805(negative regulation of synaptic transmission);GO:0050873(brown fat cell differentiation);GO:0051260(protein homooligomerization);GO:0051384(response to glucocorticoid);GO:0062023(collagen-containing extracellular matrix);GO:0070208(protein heterotrimerization);GO:0070373(negative regulation of ERK1 and ERK2 cascade);GO:0070543(response to linoleic acid);GO:0070994(detection of oxidative stress);GO:0071320(cellular response to cAMP);GO:0071639(positive regulation of monocyte chemotactic protein-1 production);GO:0071872(cellular response to epinephrine stimulus);GO:0072659(protein localization to plasma membrane);GO:0090317(negative regulation of intracellular protein transport);GO:0120162(positive regulation of cold-induced thermogenesis);GO:0120163(negative regulation of cold-induced thermogenesis);GO:1900121(negative regulation of receptor binding);GO:1904706(negative regulation of vascular smooth muscle cell proliferation);GO:1904753(negative regulation of vascular associated smooth muscle cell migration);GO:2000279(negative regulation of DNA biosynthetic process);GO:2000467(positive regulation of glycogen (starch) synthase activity);GO:2000478(positive regulation of metanephric glomerular visceral epithelial cell development);GO:2000481(positive regulation of cAMP-dependent protein kinase activity);GO:2000534(positive regulation of renal albumin absorption);GO:2000584(negative regulation of platelet-derived growth factor receptor-alpha signaling pathway);GO:2000590(negative regulation of metanephric mesenchymal cell migration)","03320(PPAR signaling pathway);04152(AMPK signaling pathway);04211(Longevity regulating pathway);04920(Adipocytokine signaling pathway);04930(Type II diabetes mellitus);04932(Non-alcoholic fatty liver disease (NAFLD))","K07296","NA","adiponectin, C1Q and collagen domain containing [Source:HGNC Symbol;Acc:HGNC:13633]",0,0,0,0,0,0,1,0,1,1,"no","no"]
[141199,0,"chr3","+",58329965,58330118,"ENST00000609225",1,154,"ENSG00000273493","AC098479","NA","NA","NA","NA","novel transcript",0,0,0,0,{"v":0.897101,"d":"0.90"},0,"-inf","-inf",1,1,"down","no"]
[180342,0,"chr7","-",76470162,76471058,"ENST00000453932",1,897,"ENSG00000233980","FDPSP2","NA","NA","NA","NA","farnesyl diphosphate synthase pseudogene 2 [Source:HGNC Symbol;Acc:HGNC:3633]",{"v":0.012948,"d":"0.01"},{"v":0.008177,"d":"0.01"},0,{"v":0.023438,"d":"0.02"},{"v":0.019278,"d":"0.02"},0,{"v":0.494545369416612,"d":"0.49"},{"v":-1.01582521550078,"d":"-1.02"},1,1,"down","no"]
[50703,0,"chr13","+",27621947,27622390,"ENST00000636226",2,100,"ENSG00000186184","POLR1D","GO:0003677(DNA binding);GO:0003899(DNA-directed 5'-3' RNA polymerase activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005736(RNA polymerase I complex);GO:0005829(cytosol);GO:0006351(transcription, DNA-templated);GO:0006361(transcription initiation from RNA polymerase I promoter);GO:0006362(transcription elongation from RNA polymerase I promoter);GO:0006363(termination of RNA polymerase I transcription);GO:0032481(positive regulation of type I interferon production);GO:0045815(positive regulation of gene expression, epigenetic);GO:0046983(protein dimerization activity)","03020(RNA polymerase);04623(Cytosolic DNA-sensing pathway)","K03020","NA","RNA polymerase I and III subunit D [Source:HGNC Symbol;Acc:HGNC:20422]",0,0,0,0,0,0,1,0,1,1,"no","no"]
[147230,0,"chr3","-",184132942,184133561,"ENST00000609288",1,620,"ENSG00000273181","AC131235","NA","NA","NA","NA","novel transcript",0,{"v":0.098668,"d":"0.10"},{"v":0.070917,"d":"0.07"},0,0,0,"inf","inf",1,1,"up","no"]
[97859,0,"chr19","+",6464271,6467221,"ENST00000600229",4,1086,"ENSG00000130545","CRB3","GO:0005515(protein binding);GO:0005886(plasma membrane);GO:0005923(bicellular tight junction);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016324(apical plasma membrane);GO:0017124(SH3 domain binding);GO:0019904(protein domain specific binding);GO:0030054(cell junction);GO:0032991(protein-containing complex);GO:0045177(apical part of cell);GO:0070062(extracellular exosome);GO:0070830(bicellular tight junction assembly);GO:0072659(protein localization to plasma membrane)","04530(Tight junction);05165(Human papillomavirus infection)","K06090","NA","crumbs cell polarity complex component 3 [Source:HGNC Symbol;Acc:HGNC:20237]",0,0,0,0,0,0,1,0,1,1,"no","no"]
[134242,0,"chr22","-",36763919,36776125,"ENST00000430701",6,531,"ENSG00000100360","IFT27","GO:0000166(nucleotide binding);GO:0001822(kidney development);GO:0003924(GTPase activity);GO:0005515(protein binding);GO:0005525(GTP binding);GO:0005737(cytoplasm);GO:0005813(centrosome);GO:0005929(cilium);GO:0006886(intracellular protein transport);GO:0007224(smoothened signaling pathway);GO:0007283(spermatogenesis);GO:0015031(protein transport);GO:0030154(cell differentiation);GO:0030992(intraciliary transport particle B);GO:0031514(motile cilium);GO:0032482(Rab protein signal transduction);GO:0035735(intraciliary transport involved in cilium assembly);GO:0036126(sperm flagellum);GO:0042073(intraciliary transport);GO:0042995(cell projection);GO:0060122(inner ear receptor cell stereocilium organization);GO:0090102(cochlea development);GO:0097225(sperm midpiece);GO:0097228(sperm principal piece);GO:0097542(ciliary tip)","NA","K07934","NA","intraflagellar transport 27 [Source:HGNC Symbol;Acc:HGNC:18626]",{"v":0.537602,"d":"0.54"},{"v":0.700079,"d":"0.70"},{"v":0.383739,"d":"0.38"},{"v":0.765604,"d":"0.77"},{"v":0.51511,"d":"0.52"},{"v":0.203704,"d":"0.20"},{"v":1.09229341061615,"d":"1.09"},{"v":0.127360443421055,"d":"0.13"},1,1,"up","no"]
[150341,0,"chr4","-",23882679,23890035,"ENST00000507380",2,2385,"ENSG00000109819","PPARGC1A","GO:0000302(response to reactive oxygen species);GO:0000422(autophagy of mitochondrion);GO:0001659(temperature homeostasis);GO:0001666(response to hypoxia);GO:0001678(cellular glucose homeostasis);GO:0001933(negative regulation of protein phosphorylation);GO:0002021(response to dietary excess);GO:0002931(response to ischemia);GO:0003676(nucleic acid binding);GO:0003677(DNA binding);GO:0003682(chromatin binding);GO:0003712(transcription coregulator activity);GO:0003713(transcription coactivator activity);GO:0003723(RNA binding);GO:0005102(signaling receptor binding);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005719(nuclear euchromatin);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0006012(galactose metabolic process);GO:0006094(gluconeogenesis);GO:0006355(regulation of transcription, DNA-templated);GO:0006367(transcription initiation from RNA polymerase II promoter);GO:0006397(mRNA processing);GO:0007005(mitochondrion organization);GO:0007568(aging);GO:0007586(digestion);GO:0007623(circadian rhythm);GO:0008134(transcription factor binding);GO:0008209(androgen metabolic process);GO:0008380(RNA splicing);GO:0009409(response to cold);GO:0009750(response to fructose);GO:0010628(positive regulation of gene expression);GO:0010822(positive regulation of mitochondrion organization);GO:0014070(response to organic cyclic compound);GO:0014732(skeletal muscle atrophy);GO:0014823(response to activity);GO:0014850(response to muscle activity);GO:0014878(response to electrical stimulus involved in regulation of muscle adaptation);GO:0014912(negative regulation of smooth muscle cell migration);GO:0016605(PML body);GO:0016922(nuclear receptor binding);GO:0019395(fatty acid oxidation);GO:0021549(cerebellum development);GO:0022626(cytosolic ribosome);GO:0022904(respiratory electron transport chain);GO:0030331(estrogen receptor binding);GO:0030374(nuclear receptor transcription coactivator activity);GO:0030521(androgen receptor signaling pathway);GO:0030900(forebrain development);GO:0031325(positive regulation of cellular metabolic process);GO:0031490(chromatin DNA binding);GO:0031625(ubiquitin protein ligase binding);GO:0031667(response to nutrient levels);GO:0032922(circadian regulation of gene expression);GO:0034599(cellular response to oxidative stress);GO:0035066(positive regulation of histone acetylation);GO:0035865(cellular response to potassium ion);GO:0042493(response to drug);GO:0042594(response to starvation);GO:0042752(regulation of circadian rhythm);GO:0042975(peroxisome proliferator activated receptor binding);GO:0043014(alpha-tubulin binding);GO:0043025(neuronal cell body);GO:0043201(response to leucine);GO:0043231(intracellular membrane-bounded organelle);GO:0043524(negative regulation of neuron apoptotic process);GO:0043565(sequence-specific DNA binding);GO:0045333(cellular respiration);GO:0045722(positive regulation of gluconeogenesis);GO:0045820(negative regulation of glycolytic process);GO:0045893(positive regulation of transcription, DNA-templated);GO:0045944(positive regulation of transcription by RNA polymerase II);GO:0046321(positive regulation of fatty acid oxidation);GO:0048511(rhythmic process);GO:0048661(positive regulation of smooth muscle cell proliferation);GO:0048662(negative regulation of smooth muscle cell proliferation);GO:0050681(androgen receptor binding);GO:0050821(protein stabilization);GO:0050873(brown fat cell differentiation);GO:0051091(positive regulation of DNA-binding transcription factor activity);GO:0051552(flavone metabolic process);GO:0051602(response to electrical stimulus);GO:0060612(adipose tissue development);GO:0065003(protein-containing complex assembly);GO:0071222(cellular response to lipopolysaccharide);GO:0071250(cellular response to nitrite);GO:0071313(cellular response to caffeine);GO:0071332(cellular response to fructose stimulus);GO:0071333(cellular response to glucose stimulus);GO:0071354(cellular response to interleukin-6);GO:0071356(cellular response to tumor necrosis factor);GO:0071372(cellular response to follicle-stimulating hormone stimulus);GO:0071392(cellular response to estradiol stimulus);GO:0071398(cellular response to fatty acid);GO:0071456(cellular response to hypoxia);GO:0071560(cellular response to transforming growth factor beta stimulus);GO:0071871(response to epinephrine);GO:0071873(response to norepinephrine);GO:0090258(negative regulation of mitochondrial fission);GO:0097009(energy homeostasis);GO:0097066(response to thyroid hormone);GO:0097067(cellular response to thyroid hormone stimulus);GO:0097440(apical dendrite);GO:0120162(positive regulation of cold-induced thermogenesis);GO:1901215(negative regulation of neuron death);GO:1901558(response to metformin);GO:1901857(positive regulation of cellular respiration);GO:1901860(positive regulation of mitochondrial DNA metabolic process);GO:1901863(positive regulation of muscle tissue development);GO:1903506(regulation of nucleic acid-templated transcription);GO:1904635(positive regulation of glomerular visceral epithelial cell apoptotic process);GO:1904637(cellular response to ionomycin);GO:1904639(cellular response to resveratrol);GO:1904640(response to methionine);GO:1990841(promoter-specific chromatin binding);GO:1990843(subsarcolemmal mitochondrion);GO:1990844(interfibrillar mitochondrion);GO:1990845(adaptive thermogenesis);GO:2000184(positive regulation of progesterone biosynthetic process);GO:2000272(negative regulation of signaling receptor activity);GO:2000310(regulation of NMDA receptor activity);GO:2001171(positive regulation of ATP biosynthetic process)","04152(AMPK signaling pathway);04211(Longevity regulating pathway);04371(Apelin signaling pathway);04714(Thermogenesis);04910(Insulin signaling pathway);04920(Adipocytokine signaling pathway);04922(Glucagon signaling pathway);04931(Insulin resistance);05016(Huntington disease)","K07202","NA","PPARG coactivator 1 alpha [Source:HGNC Symbol;Acc:HGNC:9237]",{"v":0.014443,"d":"0.01"},{"v":0.016883,"d":"0.02"},{"v":0.036875,"d":"0.04"},{"v":0.052918,"d":"0.05"},{"v":0.021755,"d":"0.02"},{"v":0.018595,"d":"0.02"},{"v":0.731236865806064,"d":"0.73"},{"v":-0.451589288201914,"d":"-0.45"},1,1,"down","no"]
[18605,0,"chr10","+",988706,997308,"ENST00000360059",5,756,"ENSG00000107937","GTPBP4","GO:0000079(regulation of cyclin-dependent protein serine/threonine kinase activity);GO:0000166(nucleotide binding);GO:0000463(maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA));GO:0001649(osteoblast differentiation);GO:0003723(RNA binding);GO:0003924(GTPase activity);GO:0005515(protein binding);GO:0005525(GTP binding);GO:0005634(nucleus);GO:0005730(nucleolus);GO:0005737(cytoplasm);GO:0005794(Golgi apparatus);GO:0005829(cytosol);GO:0008156(negative regulation of DNA replication);GO:0008285(negative regulation of cell population proliferation);GO:0016020(membrane);GO:0022408(negative regulation of cell-cell adhesion);GO:0030336(negative regulation of cell migration);GO:0031397(negative regulation of protein ubiquitination);GO:0031965(nuclear membrane);GO:0033342(negative regulation of collagen binding);GO:0042254(ribosome biogenesis);GO:0048471(perinuclear region of cytoplasm);GO:0050821(protein stabilization)","03008(Ribosome biogenesis in eukaryotes)","K06943","NA","GTP binding protein 4 [Source:HGNC Symbol;Acc:HGNC:21535]",0,0,0,{"v":0.035226,"d":"0.04"},0,0,"-inf","-inf",1,1,"down","no"]
[120572,0,"chr2","-",197498674,197499840,"ENST00000418022",3,533,"ENSG00000144381","HSPD1","GO:0000166(nucleotide binding);GO:0001530(lipopolysaccharide binding);GO:0002039(p53 binding);GO:0002368(B cell cytokine production);GO:0002755(MyD88-dependent toll-like receptor signaling pathway);GO:0002842(positive regulation of T cell mediated immune response to tumor cell);GO:0003688(DNA replication origin binding);GO:0003697(single-stranded DNA binding);GO:0003723(RNA binding);GO:0003725(double-stranded RNA binding);GO:0005515(protein binding);GO:0005524(ATP binding);GO:0005615(extracellular space);GO:0005737(cytoplasm);GO:0005739(mitochondrion);GO:0005743(mitochondrial inner membrane);GO:0005759(mitochondrial matrix);GO:0005769(early endosome);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0005905(clathrin-coated pit);GO:0006357(regulation of transcription by RNA polymerase II);GO:0006457(protein folding);GO:0006458('de novo' protein folding);GO:0006919(activation of cysteine-type endopeptidase activity involved in apoptotic process);GO:0006986(response to unfolded protein);GO:0007005(mitochondrion organization);GO:0008035(high-density lipoprotein particle binding);GO:0008637(apoptotic mitochondrial changes);GO:0009409(response to cold);GO:0009986(cell surface);GO:0016020(membrane);GO:0016032(viral process);GO:0016787(hydrolase activity);GO:0016887(ATPase activity);GO:0019899(enzyme binding);GO:0030135(coated vesicle);GO:0030141(secretory granule);GO:0031625(ubiquitin protein ligase binding);GO:0032727(positive regulation of interferon-alpha production);GO:0032729(positive regulation of interferon-gamma production);GO:0032733(positive regulation of interleukin-10 production);GO:0032735(positive regulation of interleukin-12 production);GO:0032755(positive regulation of interleukin-6 production);GO:0032991(protein-containing complex);GO:0034185(apolipoprotein binding);GO:0034186(apolipoprotein A-I binding);GO:0042026(protein refolding);GO:0042100(B cell proliferation);GO:0042110(T cell activation);GO:0042113(B cell activation);GO:0043032(positive regulation of macrophage activation);GO:0043065(positive regulation of apoptotic process);GO:0043066(negative regulation of apoptotic process);GO:0045041(protein import into mitochondrial intermembrane space);GO:0046696(lipopolysaccharide receptor complex);GO:0048291(isotype switching to IgG isotypes);GO:0050821(protein stabilization);GO:0050870(positive regulation of T cell activation);GO:0051082(unfolded protein binding);GO:0051087(chaperone binding);GO:0051131(chaperone-mediated protein complex assembly);GO:0051604(protein maturation);GO:0051702(interaction with symbiont);GO:0070062(extracellular exosome)","03018(RNA degradation);04940(Type I diabetes mellitus);05134(Legionellosis);05152(Tuberculosis)","K04077","NA","heat shock protein family D (Hsp60) member 1 [Source:HGNC Symbol;Acc:HGNC:5261]",{"v":0.344417,"d":"0.34"},{"v":0.393948,"d":"0.39"},{"v":0.431371,"d":"0.43"},{"v":0.298371,"d":"0.30"},0,{"v":0.133709,"d":"0.13"},{"v":2.70722088502129,"d":"2.71"},{"v":1.43681260337267,"d":"1.44"},1,1,"up","no"]
[72222,0,"chr16","+",19716456,19789238,"ENST00000568126",6,1774,"ENSG00000174628","IQCK","NA","NA","NA","NA","IQ motif containing K [Source:HGNC Symbol;Acc:HGNC:28556]",{"v":0.07318,"d":"0.07"},0,0,{"v":0.168013,"d":"0.17"},0,{"v":0.023018,"d":"0.02"},{"v":0.383079186100685,"d":"0.38"},{"v":-1.38428545316386,"d":"-1.38"},1,1,"down","no"]
[1190,0,"chr1","+",6806988,6871858,"ENST00000486138",4,392,"ENSG00000171735","CAMTA1","GO:0000981(DNA-binding transcription factor activity, RNA polymerase II-specific);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005730(nucleolus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0006357(regulation of transcription by RNA polymerase II);GO:0035307(positive regulation of protein dephosphorylation);GO:0043565(sequence-specific DNA binding);GO:0045944(positive regulation of transcription by RNA polymerase II);GO:0050885(neuromuscular process controlling balance);GO:0070886(positive regulation of calcineurin-NFAT signaling cascade)","NA","K21596","NA","calmodulin binding transcription activator 1 [Source:HGNC Symbol;Acc:HGNC:18806]",0,0,0,0,0,0,1,0,1,1,"no","no"]
[19334,0,"chr10","-",14518559,14572189,"ENST00000622567",4,3510,"ENSG00000065809","FAM107B","NA","NA","NA","NA","family with sequence similarity 107 member B [Source:HGNC Symbol;Acc:HGNC:23726]",0,0,{"v":1.210795,"d":"1.21"},{"v":1e-6,"d":"0.00"},0,0,1210795,{"v":20.2075231919791,"d":"20.21"},1,1,"up","no"]
[1395,0,"chr1","+",9942923,9949974,"ENST00000445884",2,440,"ENSG00000228150","AL357140","NA","NA","NA","NA","novel transcript",{"v":0.124651,"d":"0.12"},0,{"v":0.141529,"d":"0.14"},{"v":0.178091,"d":"0.18"},0,{"v":0.210827,"d":"0.21"},{"v":0.684411624044143,"d":"0.68"},{"v":-0.547063832125452,"d":"-0.55"},1,1,"down","no"]
[118541,0,"chr2","-",161222785,161254668,"ENST00000421122",4,1072,"ENSG00000235724","AC009299","NA","NA","NA","NA","novel transcript, antisense to TANK",0,0,0,0,0,0,1,0,1,1,"no","no"]
[32854,0,"chr11","+",66616715,66626489,"ENST00000409738",2,372,"ENSG00000239306","RBM14","GO:0002218(activation of innate immune response);GO:0002376(immune system process);GO:0003676(nucleic acid binding);GO:0003712(transcription coregulator activity);GO:0003723(RNA binding);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005667(transcription factor complex);GO:0005730(nucleolus);GO:0005737(cytoplasm);GO:0006260(DNA replication);GO:0006281(DNA repair);GO:0006310(DNA recombination);GO:0009725(response to hormone);GO:0016575(histone deacetylation);GO:0016592(mediator complex);GO:0016607(nuclear speck);GO:0030374(nuclear receptor transcription coactivator activity);GO:0030520(intracellular estrogen receptor signaling pathway);GO:0030674(protein binding, bridging);GO:0042921(glucocorticoid receptor signaling pathway);GO:0045087(innate immune response);GO:0045944(positive regulation of transcription by RNA polymerase II);GO:0046600(negative regulation of centriole replication);GO:0060395(SMAD protein signal transduction);GO:0098534(centriole assembly);GO:1990904(ribonucleoprotein complex)","NA","K13189","NA","RNA binding motif protein 14 [Source:HGNC Symbol;Acc:HGNC:14219]",0,0,0,0,0,0,1,0,1,1,"no","no"]
[173769,0,"chr6","-",127314866,127343359,"ENST00000526299",6,534,"ENSG00000093144","ECHDC1","GO:0003824(catalytic activity);GO:0004300(enoyl-CoA hydratase activity);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0006635(fatty acid beta-oxidation);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016829(lyase activity);GO:0016831(carboxy-lyase activity)","00640(Propanoate metabolism)","K18426","4.1.1.-;EC:4.1.1.94","ethylmalonyl-CoA decarboxylase 1 [Source:HGNC Symbol;Acc:HGNC:21489]",{"v":0.042533,"d":"0.04"},{"v":0.090719,"d":"0.09"},{"v":0.215335,"d":"0.22"},{"v":0.172933,"d":"0.17"},{"v":0.360171,"d":"0.36"},{"v":0.211995,"d":"0.21"},{"v":0.467839844101254,"d":"0.47"},{"v":-1.09591335923503,"d":"-1.10"},1,1,"down","no"]
[86962,0,"chr17","+",47548190,47592673,"ENST00000602788",11,4698,"ENSG00000141279","NPEPPS","GO:0000209(protein polyubiquitination);GO:0004177(aminopeptidase activity);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0006508(proteolysis);GO:0008233(peptidase activity);GO:0008237(metallopeptidase activity);GO:0008270(zinc ion binding);GO:0016787(hydrolase activity);GO:0042277(peptide binding);GO:0043171(peptide catabolic process);GO:0046872(metal ion binding);GO:0070006(metalloaminopeptidase activity);GO:0070062(extracellular exosome);GO:0071456(cellular response to hypoxia);GO:1903955(positive regulation of protein targeting to mitochondrion)","NA","K08776","EC:3.4.11.-","aminopeptidase puromycin sensitive [Source:HGNC Symbol;Acc:HGNC:7900]",{"v":0.043416,"d":"0.04"},{"v":0.082242,"d":"0.08"},{"v":0.005727,"d":"0.01"},{"v":0.037135,"d":"0.04"},{"v":0.00381,"d":"0.00"},{"v":0.126509,"d":"0.13"},{"v":0.784603532910531,"d":"0.78"},{"v":-0.349964263294649,"d":"-0.35"},1,1,"down","no"]
[108564,0,"chr19","+",56380230,56383924,"ENST00000651165",2,3334,"ENSG00000285996","AC006116","NA","NA","NA","NA","novel transcript, antisense to ZNF582",{"v":0.050379,"d":"0.05"},{"v":0.134718,"d":"0.13"},{"v":0.081435,"d":"0.08"},{"v":0.130476,"d":"0.13"},{"v":0.046624,"d":"0.05"},{"v":0.053152,"d":"0.05"},{"v":1.15756649236489,"d":"1.16"},{"v":0.211095066444385,"d":"0.21"},1,1,"up","no"]
[31858,0,"chr11","-",64316694,64317341,"ENST00000537918",2,559,"ENSG00000173113","TRMT112","GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0006364(rRNA processing);GO:0006415(translational termination);GO:0008276(protein methyltransferase activity);GO:0016435(rRNA (guanine) methyltransferase activity);GO:0018364(peptidyl-glutamine methylation);GO:0030488(tRNA methylation);GO:0031167(rRNA methylation);GO:0032259(methylation);GO:0032991(protein-containing complex);GO:0046982(protein heterodimerization activity);GO:0048471(perinuclear region of cytoplasm);GO:0070476(rRNA (guanine-N7)-methylation);GO:2000234(positive regulation of rRNA processing)","NA","K15448","NA","tRNA methyltransferase subunit 11-2 [Source:HGNC Symbol;Acc:HGNC:26940]",{"v":0.256657,"d":"0.26"},{"v":0.04513,"d":"0.05"},{"v":0.183451,"d":"0.18"},{"v":1e-6,"d":"0.00"},{"v":0.29849,"d":"0.30"},{"v":0.030468,"d":"0.03"},{"v":1.47507136147666,"d":"1.48"},{"v":0.56078475132743,"d":"0.56"},1,1,"up","no"]
[143411,0,"chr3","+",121927659,121928538,"ENST00000489957",2,299,"ENSG00000163406","SLC15A2","GO:0005215(transporter activity);GO:0005515(protein binding);GO:0005886(plasma membrane);GO:0005887(integral component of plasma membrane);GO:0006811(ion transport);GO:0006857(oligopeptide transport);GO:0015031(protein transport);GO:0015293(symporter activity);GO:0015333(peptide:proton symporter activity);GO:0015833(peptide transport);GO:0015893(drug transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0022857(transmembrane transporter activity);GO:0035442(dipeptide transmembrane transport);GO:0035672(oligopeptide transmembrane transport);GO:0035673(oligopeptide transmembrane transporter activity);GO:0055085(transmembrane transport);GO:0070062(extracellular exosome);GO:0071916(dipeptide transmembrane transporter activity);GO:1902600(proton transmembrane transport);GO:1904680(peptide transmembrane transporter activity)","NA","K14637","NA","solute carrier family 15 member 2 [Source:HGNC Symbol;Acc:HGNC:10921]",0,0,{"v":0.027376,"d":"0.03"},{"v":0.068819,"d":"0.07"},0,0,{"v":0.3977971199814,"d":"0.40"},{"v":-1.32989526367194,"d":"-1.33"},1,1,"down","no"]
[112490,0,"chr2","-",55287849,55296455,"ENST00000647547",5,1043,"ENSG00000115355","CCDC88A","GO:0001932(regulation of protein phosphorylation);GO:0003779(actin binding);GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0005783(endoplasmic reticulum);GO:0005794(Golgi apparatus);GO:0005813(centrosome);GO:0005814(centriole);GO:0005829(cytosol);GO:0005856(cytoskeleton);GO:0005886(plasma membrane);GO:0006260(DNA replication);GO:0006275(regulation of DNA replication);GO:0007399(nervous system development);GO:0008017(microtubule binding);GO:0010975(regulation of neuron projection development);GO:0016020(membrane);GO:0016477(cell migration);GO:0030027(lamellipodium);GO:0030030(cell projection organization);GO:0030032(lamellipodium assembly);GO:0030142(COPI-coated Golgi to ER transport vesicle);GO:0030705(cytoskeleton-dependent intracellular transport);GO:0031122(cytoplasmic microtubule organization);GO:0031252(cell leading edge);GO:0031410(cytoplasmic vesicle);GO:0031682(G-protein gamma-subunit binding);GO:0031929(TOR signaling);GO:0032148(activation of protein kinase B activity);GO:0032956(regulation of actin cytoskeleton organization);GO:0035091(phosphatidylinositol binding);GO:0036064(ciliary basal body);GO:0042127(regulation of cell population proliferation);GO:0042803(protein homodimerization activity);GO:0042995(cell projection);GO:0043422(protein kinase B binding);GO:0045724(positive regulation of cilium assembly);GO:0051959(dynein light intermediate chain binding);GO:0061024(membrane organization);GO:1903566(positive regulation of protein localization to cilium)","NA","NA","NA","coiled-coil domain containing 88A [Source:HGNC Symbol;Acc:HGNC:25523]",{"v":0.156711,"d":"0.16"},0,{"v":0.10615,"d":"0.11"},{"v":0.194606,"d":"0.19"},{"v":0.036179,"d":"0.04"},{"v":0.364817,"d":"0.36"},{"v":0.441336664416842,"d":"0.44"},{"v":-1.18004848948345,"d":"-1.18"},1,1,"down","no"]
[189859,0,"chr8","-",66964103,67012981,"ENST00000521410",4,491,"ENSG00000178125","PPP1R42","GO:0002177(manchette);GO:0003779(actin binding);GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0005813(centrosome);GO:0005815(microtubule organizing center);GO:0005856(cytoskeleton);GO:0010921(regulation of phosphatase activity);GO:0015630(microtubule cytoskeleton);GO:0015631(tubulin binding);GO:0070840(dynein complex binding)","NA","K17579","NA","protein phosphatase 1 regulatory subunit 42 [Source:HGNC Symbol;Acc:HGNC:33732]",0,0,0,0,0,0,1,0,1,1,"no","no"]
[164482,0,"chr5","-",150894392,150904983,"ENST00000418587",5,3226,"ENSG00000145908","ZNF300","GO:0000981(DNA-binding transcription factor activity, RNA polymerase II-specific);GO:0001228(DNA-binding transcription activator activity, RNA polymerase II-specific);GO:0003676(nucleic acid binding);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0005622(intracellular);GO:0005634(nucleus);GO:0005730(nucleolus);GO:0006355(regulation of transcription, DNA-templated);GO:0043565(sequence-specific DNA binding);GO:0045944(positive regulation of transcription by RNA polymerase II);GO:0046872(metal ion binding)","05168(Herpes simplex virus 1 infection)","K09228","NA","zinc finger protein 300 [Source:HGNC Symbol;Acc:HGNC:13091]",{"v":0.041351,"d":"0.04"},{"v":0.121605,"d":"0.12"},{"v":0.007904,"d":"0.01"},{"v":0.014011,"d":"0.01"},{"v":0.027776,"d":"0.03"},{"v":0.029972,"d":"0.03"},{"v":2.38102537660781,"d":"2.38"},{"v":1.25158299671541,"d":"1.25"},1,1,"up","no"]
[100357,0,"chr19","+",16111897,16127661,"ENST00000587156",5,554,"ENSG00000167461","RAB8A","GO:0000139(Golgi membrane);GO:0000166(nucleotide binding);GO:0003924(GTPase activity);GO:0005515(protein binding);GO:0005525(GTP binding);GO:0005737(cytoplasm);GO:0005768(endosome);GO:0005794(Golgi apparatus);GO:0005813(centrosome);GO:0005814(centriole);GO:0005829(cytosol);GO:0005856(cytoskeleton);GO:0005886(plasma membrane);GO:0005929(cilium);GO:0006886(intracellular protein transport);GO:0006904(vesicle docking involved in exocytosis);GO:0006914(autophagy);GO:0007409(axonogenesis);GO:0008021(synaptic vesicle);GO:0009306(protein secretion);GO:0010506(regulation of autophagy);GO:0014069(postsynaptic density);GO:0015031(protein transport);GO:0016020(membrane);GO:0017137(Rab GTPase binding);GO:0017157(regulation of exocytosis);GO:0019003(GDP binding);GO:0019901(protein kinase binding);GO:0030030(cell projection organization);GO:0030140(trans-Golgi network transport vesicle);GO:0030425(dendrite);GO:0030496(midbody);GO:0030670(phagocytic vesicle membrane);GO:0031410(cytoplasmic vesicle);GO:0031489(myosin V binding);GO:0032482(Rab protein signal transduction);GO:0032588(trans-Golgi network membrane);GO:0032869(cellular response to insulin stimulus);GO:0032880(regulation of protein localization);GO:0036064(ciliary basal body);GO:0042995(cell projection);GO:0043025(neuronal cell body);GO:0043197(dendritic spine);GO:0043687(post-translational protein modification);GO:0045202(synapse);GO:0045335(phagocytic vesicle);GO:0048169(regulation of long-term neuronal synaptic plasticity);GO:0048210(Golgi vesicle fusion to target membrane);GO:0051223(regulation of protein transport);GO:0055037(recycling endosome);GO:0055038(recycling endosome membrane);GO:0060271(cilium assembly);GO:0070062(extracellular exosome);GO:0072659(protein localization to plasma membrane);GO:0097546(ciliary base);GO:0097730(non-motile cilium);GO:0098887(neurotransmitter receptor transport, endosome to postsynaptic membrane);GO:0098969(neurotransmitter receptor transport to postsynaptic membrane);GO:0098978(glutamatergic synapse);GO:0099003(vesicle-mediated transport in synapse)","04144(Endocytosis);04152(AMPK signaling pathway);04530(Tight junction);04972(Pancreatic secretion)","K07901","NA","RAB8A, member RAS oncogene family [Source:HGNC Symbol;Acc:HGNC:7007]",{"v":0.176111,"d":"0.18"},{"v":0.212815,"d":"0.21"},{"v":0.248734,"d":"0.25"},{"v":0.120481,"d":"0.12"},{"v":0.20958,"d":"0.21"},{"v":0.526019,"d":"0.53"},{"v":0.744860293430521,"d":"0.74"},{"v":-0.424958236930812,"d":"-0.42"},1,1,"down","no"]
[153287,0,"chr4","-",89821849,89835695,"ENST00000502987",3,731,"ENSG00000145335","SNCA","GO:0000122(negative regulation of transcription by RNA polymerase II);GO:0000149(SNARE binding);GO:0000287(magnesium ion binding);GO:0001774(microglial cell activation);GO:0001921(positive regulation of receptor recycling);GO:0001933(negative regulation of protein phosphorylation);GO:0001956(positive regulation of neurotransmitter secretion);GO:0001963(synaptic transmission, dopaminergic);GO:0003779(actin binding);GO:0005507(copper ion binding);GO:0005509(calcium ion binding);GO:0005515(protein binding);GO:0005543(phospholipid binding);GO:0005576(extracellular region);GO:0005615(extracellular space);GO:0005634(nucleus);GO:0005640(nuclear outer membrane);GO:0005737(cytoplasm);GO:0005739(mitochondrion);GO:0005741(mitochondrial outer membrane);GO:0005743(mitochondrial inner membrane);GO:0005747(mitochondrial respiratory chain complex I);GO:0005758(mitochondrial intermembrane space);GO:0005759(mitochondrial matrix);GO:0005764(lysosome);GO:0005791(rough endoplasmic reticulum);GO:0005794(Golgi apparatus);GO:0005829(cytosol);GO:0005840(ribosome);GO:0005856(cytoskeleton);GO:0005886(plasma membrane);GO:0005938(cell cortex);GO:0006631(fatty acid metabolic process);GO:0006638(neutral lipid metabolic process);GO:0006644(phospholipid metabolic process);GO:0006915(apoptotic process);GO:0006919(activation of cysteine-type endopeptidase activity involved in apoptotic process);GO:0007006(mitochondrial membrane organization);GO:0007268(chemical synaptic transmission);GO:0007568(aging);GO:0008017(microtubule binding);GO:0008021(synaptic vesicle);GO:0008198(ferrous iron binding);GO:0008270(zinc ion binding);GO:0008344(adult locomotory behavior);GO:0010040(response to iron(II) ion);GO:0010517(regulation of phospholipase activity);GO:0010642(negative regulation of platelet-derived growth factor receptor signaling pathway);GO:0014048(regulation of glutamate secretion);GO:0014059(regulation of dopamine secretion);GO:0015629(actin cytoskeleton);GO:0016020(membrane);GO:0016079(synaptic vesicle exocytosis);GO:0016082(synaptic vesicle priming);GO:0016234(inclusion body);GO:0016491(oxidoreductase activity);GO:0019894(kinesin binding);GO:0019899(enzyme binding);GO:0019904(protein domain specific binding);GO:0022898(regulation of transmembrane transporter activity);GO:0030054(cell junction);GO:0030424(axon);GO:0030426(growth cone);GO:0030544(Hsp70 protein binding);GO:0030659(cytoplasmic vesicle membrane);GO:0030672(synaptic vesicle membrane);GO:0031092(platelet alpha granule membrane);GO:0031115(negative regulation of microtubule polymerization);GO:0031623(receptor internalization);GO:0031648(protein destabilization);GO:0032026(response to magnesium ion);GO:0032410(negative regulation of transporter activity);GO:0032496(response to lipopolysaccharide);GO:0032769(negative regulation of monooxygenase activity);GO:0033138(positive regulation of peptidyl-serine phosphorylation);GO:0034341(response to interferon-gamma);GO:0034599(cellular response to oxidative stress);GO:0035067(negative regulation of histone acetylation);GO:0035493(SNARE complex assembly);GO:0040012(regulation of locomotion);GO:0042220(response to cocaine);GO:0042393(histone binding);GO:0042416(dopamine biosynthetic process);GO:0042417(dopamine metabolic process);GO:0042493(response to drug);GO:0042775(mitochondrial ATP synthesis coupled electron transport);GO:0042802(identical protein binding);GO:0043014(alpha-tubulin binding);GO:0043025(neuronal cell body);GO:0043027(cysteine-type endopeptidase inhibitor activity involved in apoptotic process);GO:0043030(regulation of macrophage activation);GO:0043065(positive regulation of apoptotic process);GO:0043066(negative regulation of apoptotic process);GO:0043154(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process);GO:0043195(terminal bouton);GO:0043231(intracellular membrane-bounded organelle);GO:0043274(phospholipase binding);GO:0043524(negative regulation of neuron apoptotic process);GO:0043679(axon terminus);GO:0044212(transcription regulatory region DNA binding);GO:0044267(cellular protein metabolic process);GO:0044344(cellular response to fibroblast growth factor stimulus);GO:0045202(synapse);GO:0045807(positive regulation of endocytosis);GO:0045920(negative regulation of exocytosis);GO:0045921(positive regulation of exocytosis);GO:0045963(negative regulation of dopamine metabolic process);GO:0046872(metal ion binding);GO:0046928(regulation of neurotransmitter secretion);GO:0047485(protein N-terminus binding);GO:0048148(behavioral response to cocaine);GO:0048156(tau protein binding);GO:0048168(regulation of neuronal synaptic plasticity);GO:0048169(regulation of long-term neuronal synaptic plasticity);GO:0048471(perinuclear region of cytoplasm);GO:0048487(beta-tubulin binding);GO:0048488(synaptic vesicle endocytosis);GO:0048489(synaptic vesicle transport);GO:0050729(positive regulation of inflammatory response);GO:0050806(positive regulation of synaptic transmission);GO:0050808(synapse organization);GO:0050812(regulation of acyl-CoA biosynthetic process);GO:0051219(phosphoprotein binding);GO:0051259(protein complex oligomerization);GO:0051262(protein tetramerization);GO:0051281(positive regulation of release of sequestered calcium ion into cytosol);GO:0051583(dopamine uptake involved in synaptic transmission);GO:0051585(negative regulation of dopamine uptake involved in synaptic transmission);GO:0051612(negative regulation of serotonin uptake);GO:0051621(regulation of norepinephrine uptake);GO:0051622(negative regulation of norepinephrine uptake);GO:0055114(oxidation-reduction process);GO:0060079(excitatory postsynaptic potential);GO:0060291(long-term synaptic potentiation);GO:0060732(positive regulation of inositol phosphate biosynthetic process);GO:0061024(membrane organization);GO:0070495(negative regulation of thrombin-activated receptor signaling pathway);GO:0070555(response to interleukin-1);GO:0070840(dynein complex binding);GO:0071280(cellular response to copper ion);GO:0071872(cellular response to epinephrine stimulus);GO:0071902(positive regulation of protein serine/threonine kinase activity);GO:0097435(supramolecular fiber organization);GO:0098793(presynapse);GO:0098794(postsynapse);GO:0099512(supramolecular fiber);GO:1901214(regulation of neuron death);GO:1901215(negative regulation of neuron death);GO:1901216(positive regulation of neuron death);GO:1902957(negative regulation of mitochondrial electron transport, NADH to ubiquinone);GO:1903136(cuprous ion binding);GO:1903284(positive regulation of glutathione peroxidase activity);GO:1903285(positive regulation of hydrogen peroxide catabolic process);GO:1903421(regulation of synaptic vesicle recycling);GO:1903426(regulation of reactive oxygen species biosynthetic process);GO:1904307(response to desipramine);GO:1904715(negative regulation of chaperone-mediated autophagy);GO:1905606(regulation of presynapse assembly);GO:2000377(regulation of reactive oxygen species metabolic process)","05010(Alzheimer disease);05012(Parkinson disease)","K04528","NA","synuclein alpha [Source:HGNC Symbol;Acc:HGNC:11138]",{"v":0.111971,"d":"0.11"},{"v":2.2e-5,"d":"0.00"},{"v":0.209807,"d":"0.21"},{"v":0.090865,"d":"0.09"},{"v":0.644823,"d":"0.64"},{"v":0.068117,"d":"0.07"},{"v":0.400345855027028,"d":"0.40"},{"v":-1.32068122552386,"d":"-1.32"},1,1,"down","no"]
[106146,0,"chr19","+",48963975,48965158,"ENST00000599784",2,819,"ENSG00000267898","AC026803","NA","NA","NA","NA","novel transcript",0,0,0,0,{"v":0.077241,"d":"0.08"},0,"-inf","-inf",1,1,"down","no"]
[23093,0,"chr10","+",93517207,93520277,"ENST00000496302",3,710,"ENSG00000138180","CEP55","GO:0000281(mitotic cytokinesis);GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0005813(centrosome);GO:0005814(centriole);GO:0005815(microtubule organizing center);GO:0005856(cytoskeleton);GO:0005886(plasma membrane);GO:0007049(cell cycle);GO:0007275(multicellular organism development);GO:0014066(regulation of phosphatidylinositol 3-kinase signaling);GO:0016020(membrane);GO:0030496(midbody);GO:0032154(cleavage furrow);GO:0045171(intercellular bridge);GO:0045184(establishment of protein localization);GO:0051301(cell division);GO:0061952(midbody abscission);GO:0072001(renal system development);GO:0090543(Flemming body);GO:1904888(cranial skeletal system development)","NA","K16456","NA","centrosomal protein 55 [Source:HGNC Symbol;Acc:HGNC:1161]",{"v":0.026169,"d":"0.03"},{"v":0.001989,"d":"0.00"},0,{"v":0.000698,"d":"0.00"},{"v":0.000788,"d":"0.00"},{"v":0.000418,"d":"0.00"},{"v":14.7888655462185,"d":"14.79"},{"v":3.88643948244148,"d":"3.89"},1,1,"up","no"]
[128415,0,"chr20","-",62307955,62309257,"ENST00000492698",2,894,"ENSG00000130702","LAMA5","GO:0001525(angiogenesis);GO:0001658(branching involved in ureteric bud morphogenesis);GO:0001738(morphogenesis of a polarized epithelium);GO:0001755(neural crest cell migration);GO:0001942(hair follicle development);GO:0005102(signaling receptor binding);GO:0005178(integrin binding);GO:0005201(extracellular matrix structural constituent);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0005604(basement membrane);GO:0005610(laminin-5 complex);GO:0005615(extracellular space);GO:0005634(nucleus);GO:0007010(cytoskeleton organization);GO:0007155(cell adhesion);GO:0007229(integrin-mediated signaling pathway);GO:0007517(muscle organ development);GO:0008037(cell recognition);GO:0008283(cell population proliferation);GO:0009887(animal organ morphogenesis);GO:0016331(morphogenesis of embryonic epithelium);GO:0016477(cell migration);GO:0019221(cytokine-mediated signaling pathway);GO:0030154(cell differentiation);GO:0030155(regulation of cell adhesion);GO:0030198(extracellular matrix organization);GO:0030324(lung development);GO:0030334(regulation of cell migration);GO:0031012(extracellular matrix);GO:0031594(neuromuscular junction);GO:0034446(substrate adhesion-dependent cell spreading);GO:0042127(regulation of cell population proliferation);GO:0042475(odontogenesis of dentin-containing tooth);GO:0043083(synaptic cleft);GO:0043259(laminin-10 complex);GO:0043260(laminin-11 complex);GO:0045446(endothelial cell differentiation);GO:0045995(regulation of embryonic development);GO:0048041(focal adhesion assembly);GO:0048754(branching morphogenesis of an epithelial tube);GO:0060271(cilium assembly);GO:0060445(branching involved in salivary gland morphogenesis);GO:0062023(collagen-containing extracellular matrix);GO:0070062(extracellular exosome);GO:0072659(protein localization to plasma membrane)","04151(PI3K-Akt signaling pathway);04510(Focal adhesion);04512(ECM-receptor interaction);05145(Toxoplasmosis);05146(Amoebiasis);05165(Human papillomavirus infection);05200(Pathways in cancer);05222(Small cell lung cancer)","NA","NA","laminin subunit alpha 5 [Source:HGNC Symbol;Acc:HGNC:6485]",{"v":0.167439,"d":"0.17"},{"v":0.356354,"d":"0.36"},{"v":0.225711,"d":"0.23"},{"v":0.253841,"d":"0.25"},{"v":0.145099,"d":"0.15"},{"v":0.442963,"d":"0.44"},{"v":0.890249826880294,"d":"0.89"},{"v":-0.16771784484827,"d":"-0.17"},1,1,"down","no"]
[71025,0,"chr16","-",4699754,4734254,"ENST00000590730",7,2198,"ENSG00000168096","ANKS3","GO:0005515(protein binding)","NA","NA","NA","ankyrin repeat and sterile alpha motif domain containing 3 [Source:HGNC Symbol;Acc:HGNC:29422]",{"v":0.101746,"d":"0.10"},{"v":0.132331,"d":"0.13"},{"v":0.210771,"d":"0.21"},{"v":0.15799,"d":"0.16"},{"v":0.044524,"d":"0.04"},{"v":0.218382,"d":"0.22"},{"v":1.05690716946704,"d":"1.06"},{"v":0.0798486671360291,"d":"0.08"},1,1,"up","no"]
[170596,0,"chr6","-",41937713,42048688,"ENST00000514382",3,476,"ENSG00000112576","CCND3","GO:0000079(regulation of cyclin-dependent protein serine/threonine kinase activity);GO:0000122(negative regulation of transcription by RNA polymerase II);GO:0000278(mitotic cell cycle);GO:0000307(cyclin-dependent protein kinase holoenzyme complex);GO:0001934(positive regulation of protein phosphorylation);GO:0004672(protein kinase activity);GO:0004693(cyclin-dependent protein serine/threonine kinase activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0006468(protein phosphorylation);GO:0007049(cell cycle);GO:0007088(regulation of mitotic nuclear division);GO:0007165(signal transduction);GO:0008284(positive regulation of cell population proliferation);GO:0016020(membrane);GO:0016538(cyclin-dependent protein serine/threonine kinase regulator activity);GO:0019901(protein kinase binding);GO:0042098(T cell proliferation);GO:0042127(regulation of cell population proliferation);GO:0045737(positive regulation of cyclin-dependent protein serine/threonine kinase activity);GO:0045787(positive regulation of cell cycle);GO:0046626(regulation of insulin receptor signaling pathway);GO:0051301(cell division);GO:0051726(regulation of cell cycle);GO:1900087(positive regulation of G1/S transition of mitotic cell cycle)","04110(Cell cycle);04115(p53 signaling pathway);04151(PI3K-Akt signaling pathway);04218(Cellular senescence);04310(Wnt signaling pathway);04390(Hippo signaling pathway);04510(Focal adhesion);04630(Jak-STAT signaling pathway);05162(Measles);05165(Human papillomavirus infection);05166(Human T-cell leukemia virus 1 infection);05169(Epstein-Barr virus infection);05200(Pathways in cancer);05203(Viral carcinogenesis)","NA","NA","cyclin D3 [Source:HGNC Symbol;Acc:HGNC:1585]",{"v":0.024908,"d":"0.02"},{"v":0.023605,"d":"0.02"},0,{"v":0.022554,"d":"0.02"},{"v":0.03713,"d":"0.04"},{"v":0.023784,"d":"0.02"},{"v":0.581216753725979,"d":"0.58"},{"v":-0.782851805252771,"d":"-0.78"},1,1,"down","no"]
[73722,0,"chr16","+",30196312,30197530,"ENST00000564268",2,1140,"ENSG00000132207","SLX1A","GO:0000724(double-strand break repair via homologous recombination);GO:0004518(nuclease activity);GO:0004519(endonuclease activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0006281(DNA repair);GO:0006310(DNA recombination);GO:0006974(cellular response to DNA damage stimulus);GO:0008821(crossover junction endodeoxyribonuclease activity);GO:0010792(DNA double-strand break processing involved in repair via single-strand annealing);GO:0010833(telomere maintenance via telomere lengthening);GO:0016787(hydrolase activity);GO:0017108(5'-flap endonuclease activity);GO:0033557(Slx1-Slx4 complex);GO:0036297(interstrand cross-link repair);GO:0046872(metal ion binding);GO:0061820(telomeric D-loop disassembly);GO:0090305(nucleic acid phosphodiester bond hydrolysis);GO:0090656(t-circle formation);GO:1904357(negative regulation of telomere maintenance via telomere lengthening);GO:1904431(positive regulation of t-circle formation)","03460(Fanconi anemia pathway)","K15078","EC:3.6.1.-","SLX1 homolog A, structure-specific endonuclease subunit [Source:HGNC Symbol;Acc:HGNC:20922]",{"v":0.09712,"d":"0.10"},{"v":0.270417,"d":"0.27"},{"v":0.22288,"d":"0.22"},{"v":0.084675,"d":"0.08"},{"v":0.375119,"d":"0.38"},{"v":0.035711,"d":"0.04"},{"v":1.19154599852676,"d":"1.19"},{"v":0.252834646505526,"d":"0.25"},1,1,"up","no"]
[59021,0,"chr14","-",81270429,81278818,"ENST00000555284",2,2362,"ENSG00000140022","STON2","GO:0002244(hematopoietic progenitor cell differentiation);GO:0005515(protein binding);GO:0005623(cell);GO:0005730(nucleolus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0006897(endocytosis);GO:0008021(synaptic vesicle);GO:0016020(membrane);GO:0030054(cell junction);GO:0030100(regulation of endocytosis);GO:0030136(clathrin-coated vesicle);GO:0036465(synaptic vesicle recycling);GO:0043005(neuron projection);GO:0045202(synapse);GO:0048488(synaptic vesicle endocytosis);GO:0061024(membrane organization);GO:0098793(presynapse)","NA","K20067","NA","stonin 2 [Source:HGNC Symbol;Acc:HGNC:30652]",{"v":0.039245,"d":"0.04"},{"v":0.064341,"d":"0.06"},{"v":0.097707,"d":"0.10"},{"v":0.048535,"d":"0.05"},0,{"v":0.091298,"d":"0.09"},{"v":1.43952428968841,"d":"1.44"},{"v":0.525592132296536,"d":"0.53"},1,1,"up","no"]
[92206,0,"chr17","+",82458664,82488265,"ENST00000412079",13,1760,"ENSG00000141562","NARF","GO:0005521(lamin binding);GO:0005634(nucleus);GO:0005638(lamin filament);GO:0005652(nuclear lamina);GO:0005730(nucleolus);GO:0031981(nuclear lumen)","NA","NA","NA","nuclear prelamin A recognition factor [Source:HGNC Symbol;Acc:HGNC:29916]",0,0,{"v":0.002554,"d":"0.00"},{"v":0.002407,"d":"0.00"},0,{"v":0.006566,"d":"0.01"},{"v":0.284631672796166,"d":"0.28"},{"v":-1.81283188613778,"d":"-1.81"},1,1,"down","no"]
[109795,0,"chr2","+",9474858,9488314,"ENST00000481688",6,1011,"ENSG00000134330","IAH1","GO:0006629(lipid metabolic process);GO:0016042(lipid catabolic process);GO:0016787(hydrolase activity);GO:0016788(hydrolase activity, acting on ester bonds)","NA","NA","NA","isoamyl acetate hydrolyzing esterase 1 (putative) [Source:HGNC Symbol;Acc:HGNC:27696]",{"v":0.083067,"d":"0.08"},{"v":0.081222,"d":"0.08"},{"v":0.089454,"d":"0.09"},{"v":0.10969,"d":"0.11"},{"v":5.131129,"d":"5.13"},{"v":0.107375,"d":"0.11"},{"v":0.0474446140136278,"d":"0.05"},{"v":-4.39761187021776,"d":"-4.40"},1,1,"down","no"]
[145520,0,"chr3","+",151086889,151437072,"ENST00000474524",43,10744,"ENSG00000144893","MED12L","GO:0003712(transcription coregulator activity);GO:0003713(transcription coactivator activity);GO:0005634(nucleus);GO:0006357(regulation of transcription by RNA polymerase II);GO:0008013(beta-catenin binding);GO:0016592(mediator complex);GO:1903508(positive regulation of nucleic acid-templated transcription)","04919(Thyroid hormone signaling pathway)","K15162","NA","mediator complex subunit 12 like [Source:HGNC Symbol;Acc:HGNC:16050]",{"v":0.025127,"d":"0.03"},{"v":0.007798,"d":"0.01"},{"v":0.029195,"d":"0.03"},{"v":0.015599,"d":"0.02"},{"v":0.021503,"d":"0.02"},{"v":0.016421,"d":"0.02"},{"v":1.16062253610597,"d":"1.16"},{"v":0.214898847456147,"d":"0.21"},1,1,"up","no"]
[113577,0,"chr2","-",70447284,70553826,"ENST00000295400",6,4117,"ENSG00000163235","TGFA","GO:0000139(Golgi membrane);GO:0000165(MAPK cascade);GO:0000187(activation of MAPK activity);GO:0001525(angiogenesis);GO:0005154(epidermal growth factor receptor binding);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0005615(extracellular space);GO:0005634(nucleus);GO:0005789(endoplasmic reticulum membrane);GO:0005886(plasma membrane);GO:0006357(regulation of transcription by RNA polymerase II);GO:0006888(endoplasmic reticulum to Golgi vesicle-mediated transport);GO:0007165(signal transduction);GO:0007173(epidermal growth factor receptor signaling pathway);GO:0008083(growth factor activity);GO:0008284(positive regulation of cell population proliferation);GO:0009986(cell surface);GO:0012507(ER to Golgi transport vesicle membrane);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016323(basolateral plasma membrane);GO:0030665(clathrin-coated vesicle membrane);GO:0031410(cytoplasmic vesicle);GO:0033116(endoplasmic reticulum-Golgi intermediate compartment membrane);GO:0035556(intracellular signal transduction);GO:0042059(negative regulation of epidermal growth factor receptor signaling pathway);GO:0042060(wound healing);GO:0042493(response to drug);GO:0043066(negative regulation of apoptotic process);GO:0045741(positive regulation of epidermal growth factor-activated receptor activity);GO:0045840(positive regulation of mitotic nuclear division);GO:0048208(COPII vesicle coating);GO:0048471(perinuclear region of cytoplasm);GO:0048523(negative regulation of cellular process);GO:0050679(positive regulation of epithelial cell proliferation);GO:0050731(positive regulation of peptidyl-tyrosine phosphorylation);GO:0051781(positive regulation of cell division);GO:0051897(positive regulation of protein kinase B signaling);GO:0060749(mammary gland alveolus development);GO:0061024(membrane organization);GO:0072574(hepatocyte proliferation)","01521(EGFR tyrosine kinase inhibitor resistance);04010(MAPK signaling pathway);04012(ErbB signaling pathway);04014(Ras signaling pathway);04151(PI3K-Akt signaling pathway);04915(Estrogen signaling pathway);05200(Pathways in cancer);05210(Colorectal cancer);05211(Renal cell carcinoma);05212(Pancreatic cancer);05214(Glioma);05215(Prostate cancer);05223(Non-small cell lung cancer);05225(Hepatocellular carcinoma)","K08774","NA","transforming growth factor alpha [Source:HGNC Symbol;Acc:HGNC:11765]",{"v":0.162574,"d":"0.16"},{"v":0.058829,"d":"0.06"},{"v":0.053398,"d":"0.05"},{"v":0.047472,"d":"0.05"},0,{"v":0.032235,"d":"0.03"},{"v":3.44763947959401,"d":"3.45"},{"v":1.78560891938192,"d":"1.79"},1,1,"up","no"]
[4096,0,"chr1","-",33024120,33036868,"ENST00000551979",2,581,"ENSG00000004455","AK2","GO:0000166(nucleotide binding);GO:0004017(adenylate kinase activity);GO:0005524(ATP binding);GO:0005739(mitochondrion);GO:0005758(mitochondrial intermembrane space);GO:0006139(nucleobase-containing compound metabolic process);GO:0006172(ADP biosynthetic process);GO:0015949(nucleobase-containing small molecule interconversion);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0016740(transferase activity);GO:0016776(phosphotransferase activity, phosphate group as acceptor);GO:0019205(nucleobase-containing compound kinase activity);GO:0036126(sperm flagellum);GO:0046033(AMP metabolic process);GO:0046034(ATP metabolic process);GO:0046940(nucleoside monophosphate phosphorylation);GO:0070062(extracellular exosome);GO:0097226(sperm mitochondrial sheath)","00230(Purine metabolism);00730(Thiamine metabolism)","NA","NA","adenylate kinase 2 [Source:HGNC Symbol;Acc:HGNC:362]",{"v":0.244106,"d":"0.24"},{"v":0.362294,"d":"0.36"},{"v":0.305677,"d":"0.31"},{"v":0.260665,"d":"0.26"},{"v":0.177367,"d":"0.18"},{"v":0.234687,"d":"0.23"},{"v":1.35580680789453,"d":"1.36"},{"v":0.439151620104715,"d":"0.44"},1,1,"up","no"]
[41515,0,"chr12","+",32352349,32354144,"ENST00000614539",1,1796,"ENSG00000276115","AC026356","NA","NA","NA","NA","novel transcript, sense intronic to BICD1",{"v":0.02338,"d":"0.02"},{"v":0.051787,"d":"0.05"},0,{"v":0.070237,"d":"0.07"},{"v":0.086654,"d":"0.09"},{"v":0.074068,"d":"0.07"},{"v":0.325456033321932,"d":"0.33"},{"v":-1.61946543565226,"d":"-1.62"},1,1,"down","no"]
[115966,0,"chr2","-",106112643,106160584,"ENST00000444193",7,800,"ENSG00000115652","UXS1","GO:0003824(catalytic activity);GO:0005737(cytoplasm);GO:0005794(Golgi apparatus);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016829(lyase activity);GO:0016831(carboxy-lyase activity);GO:0032580(Golgi cisterna membrane);GO:0033320(UDP-D-xylose biosynthetic process);GO:0042803(protein homodimerization activity);GO:0048040(UDP-glucuronate decarboxylase activity);GO:0050662(coenzyme binding);GO:0051262(protein tetramerization);GO:0070062(extracellular exosome);GO:0070403(NAD+ binding)","00520(Amino sugar and nucleotide sugar metabolism)","K08678","EC:4.1.1.35","UDP-glucuronate decarboxylase 1 [Source:HGNC Symbol;Acc:HGNC:17729]",{"v":0.012474,"d":"0.01"},{"v":0.109091,"d":"0.11"},{"v":0.014466,"d":"0.01"},{"v":0.113386,"d":"0.11"},{"v":0.017151,"d":"0.02"},{"v":0.31856,"d":"0.32"},{"v":0.302898928293887,"d":"0.30"},{"v":-1.72309162123684,"d":"-1.72"},1,1,"down","no"]
[27159,0,"chr11","+",7632346,7639811,"ENST00000532381",4,769,"ENSG00000166387","PPFIBP2","GO:0003674(molecular_function);GO:0005515(protein binding);GO:0005615(extracellular space);GO:0005829(cytosol);GO:0042802(identical protein binding);GO:0098793(presynapse)","NA","NA","NA","PPFIA binding protein 2 [Source:HGNC Symbol;Acc:HGNC:9250]",{"v":0.109822,"d":"0.11"},{"v":0.101338,"d":"0.10"},{"v":0.305551,"d":"0.31"},{"v":0.150125,"d":"0.15"},{"v":0.31281,"d":"0.31"},{"v":0.136239,"d":"0.14"},{"v":0.862372199060707,"d":"0.86"},{"v":-0.213617425289225,"d":"-0.21"},1,1,"down","no"]
[40801,0,"chr12","+",21501824,21515867,"ENST00000539663",7,876,"ENSG00000111711","GOLT1B","GO:0000139(Golgi membrane);GO:0005783(endoplasmic reticulum);GO:0005794(Golgi apparatus);GO:0015031(protein transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016192(vesicle-mediated transport);GO:0032991(protein-containing complex);GO:0043123(positive regulation of I-kappaB kinase/NF-kappaB signaling)","NA","NA","NA","golgi transport 1B [Source:HGNC Symbol;Acc:HGNC:20175]",0,0,0,0,0,{"v":0.005303,"d":"0.01"},"-inf","-inf",1,1,"down","no"]
[112044,0,"chr2","+",46576128,46577125,"ENST00000494370",2,689,"ENSG00000119729","RHOQ","GO:0000166(nucleotide binding);GO:0003924(GTPase activity);GO:0005515(protein binding);GO:0005522(profilin binding);GO:0005525(GTP binding);GO:0005622(intracellular);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005884(actin filament);GO:0005886(plasma membrane);GO:0005938(cell cortex);GO:0006897(endocytosis);GO:0007015(actin filament organization);GO:0007163(establishment or maintenance of cell polarity);GO:0007264(small GTPase mediated signal transduction);GO:0007266(Rho protein signal transduction);GO:0008286(insulin receptor signaling pathway);GO:0008360(regulation of cell shape);GO:0016020(membrane);GO:0019901(protein kinase binding);GO:0030031(cell projection assembly);GO:0030036(actin cytoskeleton organization);GO:0030660(Golgi-associated vesicle membrane);GO:0030866(cortical actin cytoskeleton organization);GO:0032427(GBD domain binding);GO:0032869(cellular response to insulin stimulus);GO:0032956(regulation of actin cytoskeleton organization);GO:0042995(cell projection);GO:0045121(membrane raft);GO:0045944(positive regulation of transcription by RNA polymerase II);GO:0046039(GTP metabolic process);GO:0046326(positive regulation of glucose import);GO:0051056(regulation of small GTPase mediated signal transduction);GO:0051491(positive regulation of filopodium assembly);GO:0070062(extracellular exosome);GO:1903077(negative regulation of protein localization to plasma membrane)","04910(Insulin signaling pathway)","K07194","NA","ras homolog family member Q [Source:HGNC Symbol;Acc:HGNC:17736]",{"v":0.24309,"d":"0.24"},{"v":1.080386,"d":"1.08"},{"v":0.60675,"d":"0.61"},{"v":0.267529,"d":"0.27"},{"v":0.112207,"d":"0.11"},{"v":0.968858,"d":"0.97"},{"v":1.43128769666779,"d":"1.43"},{"v":0.517313690819705,"d":"0.52"},1,1,"up","no"]
[141254,0,"chr3","+",58572744,58574319,"ENST00000472513",3,350,"ENSG00000243384","AC119424","NA","NA","NA","NA","novel transcript",{"v":0.045518,"d":"0.05"},0,{"v":0.075374,"d":"0.08"},0,0,{"v":0.133764,"d":"0.13"},{"v":0.903770820250591,"d":"0.90"},{"v":-0.145971116943896,"d":"-0.15"},1,1,"down","no"]
[54541,0,"chr14","+",22766719,22771730,"ENST00000358043",10,1750,"ENSG00000155463","OXA1L","GO:0005515(protein binding);GO:0005739(mitochondrion);GO:0005743(mitochondrial inner membrane);GO:0005746(mitochondrial respirasome);GO:0005759(mitochondrial matrix);GO:0009060(aerobic respiration);GO:0015031(protein transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0031305(integral component of mitochondrial inner membrane);GO:0031966(mitochondrial membrane);GO:0032592(integral component of mitochondrial membrane);GO:0032780(negative regulation of ATPase activity);GO:0032977(membrane insertase activity);GO:0032979(protein insertion into mitochondrial inner membrane from matrix);GO:0032981(mitochondrial respiratory chain complex I assembly);GO:0032991(protein-containing complex);GO:0033615(mitochondrial proton-transporting ATP synthase complex assembly);GO:0033617(mitochondrial respiratory chain complex IV assembly);GO:0042803(protein homodimerization activity);GO:0051205(protein insertion into membrane);GO:0051262(protein tetramerization);GO:0051354(negative regulation of oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0065003(protein-containing complex assembly);GO:0070125(mitochondrial translational elongation);GO:0070126(mitochondrial translational termination);GO:0097177(mitochondrial ribosome binding)","03060(Protein export)","K03217","NA","OXA1L, mitochondrial inner membrane protein [Source:HGNC Symbol;Acc:HGNC:8526]",{"v":1.7e-5,"d":"0.00"},{"v":4.3e-5,"d":"0.00"},{"v":0.000257,"d":"0.00"},{"v":1.2e-5,"d":"0.00"},{"v":0.000521,"d":"0.00"},{"v":0.043302,"d":"0.04"},{"v":0.00723166419527775,"d":"0.01"},{"v":-7.11145659737572,"d":"-7.11"},1,1,"down","no"]
[203560,0,"chrX","-",54171542,54182778,"ENST00000497680",2,637,"ENSG00000184083","FAM120C","GO:0003723(RNA binding);GO:0005634(nucleus)","NA","NA","NA","family with sequence similarity 120C [Source:HGNC Symbol;Acc:HGNC:16949]",{"v":0.0993,"d":"0.10"},0,{"v":0.103536,"d":"0.10"},0,{"v":0.1803,"d":"0.18"},{"v":0.141196,"d":"0.14"},{"v":0.630912981810038,"d":"0.63"},{"v":-0.664487058567463,"d":"-0.66"},1,1,"down","no"]
[90149,0,"chr17","+",75218293,75225949,"ENST00000577561",4,524,"ENSG00000125450","NUP85","GO:0000775(chromosome, centromeric region);GO:0000776(kinetochore);GO:0000777(condensed chromosome kinetochore);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005635(nuclear envelope);GO:0005643(nuclear pore);GO:0005694(chromosome);GO:0005737(cytoplasm);GO:0005819(spindle);GO:0005829(cytosol);GO:0005856(cytoskeleton);GO:0006110(regulation of glycolytic process);GO:0006406(mRNA export from nucleus);GO:0006409(tRNA export from nucleus);GO:0006606(protein import into nucleus);GO:0006913(nucleocytoplasmic transport);GO:0006935(chemotaxis);GO:0015031(protein transport);GO:0016020(membrane);GO:0016032(viral process);GO:0016925(protein sumoylation);GO:0017056(structural constituent of nuclear pore);GO:0019083(viral transcription);GO:0030032(lamellipodium assembly);GO:0031080(nuclear pore outer ring);GO:0031965(nuclear membrane);GO:0043657(host cell);GO:0045893(positive regulation of transcription, DNA-templated);GO:0048246(macrophage chemotaxis);GO:0051028(mRNA transport);GO:0060964(regulation of gene silencing by miRNA);GO:0072006(nephron development);GO:0075733(intracellular transport of virus);GO:1900034(regulation of cellular response to heat)","03013(RNA transport)","K14304","NA","nucleoporin 85 [Source:HGNC Symbol;Acc:HGNC:8734]",{"v":0.113369,"d":"0.11"},{"v":0.360984,"d":"0.36"},{"v":0.044304,"d":"0.04"},{"v":0.057739,"d":"0.06"},{"v":0.058374,"d":"0.06"},{"v":0.05357,"d":"0.05"},{"v":3.05662323273398,"d":"3.06"},{"v":1.61193873287088,"d":"1.61"},1,1,"up","no"]
[66129,0,"chr15","+",72566370,72580779,"ENST00000565950",5,559,"ENSG00000166233","ARIH1","GO:0000151(ubiquitin ligase complex);GO:0000209(protein polyubiquitination);GO:0004842(ubiquitin-protein transferase activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0006511(ubiquitin-dependent protein catabolic process);GO:0008270(zinc ion binding);GO:0015030(Cajal body);GO:0016567(protein ubiquitination);GO:0016604(nuclear body);GO:0016740(transferase activity);GO:0019005(SCF ubiquitin ligase complex);GO:0019787(ubiquitin-like protein transferase activity);GO:0031462(Cul2-RING ubiquitin ligase complex);GO:0031463(Cul3-RING ubiquitin ligase complex);GO:0031464(Cul4A-RING E3 ubiquitin ligase complex);GO:0031624(ubiquitin conjugating enzyme binding);GO:0031625(ubiquitin protein ligase binding);GO:0032436(positive regulation of proteasomal ubiquitin-dependent protein catabolic process);GO:0046872(metal ion binding);GO:0061630(ubiquitin protein ligase activity);GO:0097413(Lewy body)","NA","K11968","EC:2.3.2.31","ariadne RBR E3 ubiquitin protein ligase 1 [Source:HGNC Symbol;Acc:HGNC:689]",{"v":0.015376,"d":"0.02"},{"v":0.015636,"d":"0.02"},{"v":0.00142,"d":"0.00"},{"v":0.001368,"d":"0.00"},{"v":0.02121,"d":"0.02"},{"v":0.017077,"d":"0.02"},{"v":0.817853990669525,"d":"0.82"},{"v":-0.290084789298583,"d":"-0.29"},1,1,"down","no"]
[89206,0,"chr17","+",64572829,64573081,"ENST00000606889",1,253,"ENSG00000271779","AC009994","NA","NA","NA","NA","G protein-coupled receptor 128 (GPR128) pseudogene",{"v":0.230123,"d":"0.23"},0,0,{"v":0.041255,"d":"0.04"},0,0,{"v":5.57806326505878,"d":"5.58"},{"v":2.47976429716095,"d":"2.48"},1,1,"up","no"]
[90281,0,"chr17","-",75505319,75515440,"ENST00000581870",10,1612,"ENSG00000177303","CASKIN2","GO:0003674(molecular_function);GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0008150(biological_process);GO:0016020(membrane)","NA","K21952","NA","CASK interacting protein 2 [Source:HGNC Symbol;Acc:HGNC:18200]",{"v":0.605079,"d":"0.61"},{"v":0.227058,"d":"0.23"},{"v":0.326533,"d":"0.33"},{"v":0.036307,"d":"0.04"},{"v":0.31052,"d":"0.31"},{"v":0.296113,"d":"0.30"},{"v":1.80214327931067,"d":"1.80"},{"v":0.84971371710793,"d":"0.85"},1,1,"up","no"]
[189166,0,"chr8","-",52110839,52409743,"ENST00000276480",26,6187,"ENSG00000147488","ST18","GO:0000977(RNA polymerase II regulatory region sequence-specific DNA binding);GO:0000978(RNA polymerase II proximal promoter sequence-specific DNA binding);GO:0000981(DNA-binding transcription factor activity, RNA polymerase II-specific);GO:0001228(DNA-binding transcription activator activity, RNA polymerase II-specific);GO:0003677(DNA binding);GO:0005634(nucleus);GO:0006355(regulation of transcription, DNA-templated);GO:0008270(zinc ion binding);GO:0008285(negative regulation of cell population proliferation);GO:0032993(protein-DNA complex);GO:0033209(tumor necrosis factor-mediated signaling pathway);GO:0045944(positive regulation of transcription by RNA polymerase II);GO:0046872(metal ion binding);GO:0070102(interleukin-6-mediated signaling pathway);GO:0070498(interleukin-1-mediated signaling pathway);GO:0140110(transcription regulator activity);GO:2001269(positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway)","NA","NA","NA","ST18, C2H2C-type zinc finger [Source:HGNC Symbol;Acc:HGNC:18695]",0,0,0,0,0,0,1,0,1,1,"no","no"]
[132762,0,"chr22","+",24098113,24119606,"ENST00000467937",3,593,"ENSG00000099991","CABIN1","GO:0004864(protein phosphatase inhibitor activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0006325(chromatin organization);GO:0006336(DNA replication-independent nucleosome assembly);GO:0007166(cell surface receptor signaling pathway);GO:0016235(aggresome);GO:0031491(nucleosome binding);GO:0032515(negative regulation of phosphoprotein phosphatase activity)","NA","K17613","NA","calcineurin binding protein 1 [Source:HGNC Symbol;Acc:HGNC:24187]",{"v":0.007607,"d":"0.01"},0,0,{"v":0.013337,"d":"0.01"},0,{"v":0.014609,"d":"0.01"},{"v":0.27220353538968,"d":"0.27"},{"v":-1.87724229014672,"d":"-1.88"},1,1,"down","no"]
[130465,0,"chr21","-",39343137,39349054,"ENST00000464078",5,508,"ENSG00000205581","HMGN1","GO:0000720(pyrimidine dimer repair by nucleotide-excision repair);GO:0000785(chromatin);GO:0003677(DNA binding);GO:0003682(chromatin binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0006283(transcription-coupled nucleotide-excision repair);GO:0006325(chromatin organization);GO:0006357(regulation of transcription by RNA polymerase II);GO:0010224(response to UV-B);GO:0010225(response to UV-C);GO:0031492(nucleosomal DNA binding);GO:0032786(positive regulation of DNA-templated transcription, elongation);GO:0040034(regulation of development, heterochronic);GO:0048597(post-embryonic camera-type eye morphogenesis);GO:0050678(regulation of epithelial cell proliferation);GO:1901666(positive regulation of NAD+ ADP-ribosyltransferase activity)","NA","K11299","NA","high mobility group nucleosome binding domain 1 [Source:HGNC Symbol;Acc:HGNC:4984]",{"v":1.466572,"d":"1.47"},{"v":0.971146,"d":"0.97"},{"v":0.947556,"d":"0.95"},{"v":1.093931,"d":"1.09"},{"v":0.9299,"d":"0.93"},{"v":0.806871,"d":"0.81"},{"v":1.19591323989597,"d":"1.20"},{"v":0.258112729910577,"d":"0.26"},1,1,"up","no"]
[140003,0,"chr3","+",49470132,49535618,"ENST00000545947",6,5829,"ENSG00000173402","DAG1","GO:0001618(virus receptor activity);GO:0001954(positive regulation of cell-matrix adhesion);GO:0002011(morphogenesis of an epithelial sheet);GO:0002162(dystroglycan binding);GO:0003779(actin binding);GO:0005509(calcium ion binding);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0005604(basement membrane);GO:0005615(extracellular space);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0005788(endoplasmic reticulum lumen);GO:0005796(Golgi lumen);GO:0005829(cytosol);GO:0005856(cytoskeleton);GO:0005886(plasma membrane);GO:0005911(cell-cell junction);GO:0005913(cell-cell adherens junction);GO:0005925(focal adhesion);GO:0006509(membrane protein ectodomain proteolysis);GO:0007016(cytoskeletal anchoring at plasma membrane);GO:0007568(aging);GO:0008307(structural constituent of muscle);GO:0009897(external side of plasma membrane);GO:0010470(regulation of gastrulation);GO:0010717(regulation of epithelial to mesenchymal transition);GO:0014037(Schwann cell differentiation);GO:0014044(Schwann cell development);GO:0014894(response to denervation involved in regulation of muscle adaptation);GO:0015631(tubulin binding);GO:0016010(dystrophin-associated glycoprotein complex);GO:0016011(dystroglycan complex);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016032(viral process);GO:0016323(basolateral plasma membrane);GO:0016340(calcium-dependent cell-matrix adhesion);GO:0016476(regulation of embryonic cell shape);GO:0017166(vinculin binding);GO:0019048(modulation by virus of host morphology or physiology);GO:0021675(nerve development);GO:0021682(nerve maturation);GO:0022011(myelination in peripheral nervous system);GO:0030027(lamellipodium);GO:0030054(cell junction);GO:0030175(filopodium);GO:0030198(extracellular matrix organization);GO:0030336(negative regulation of cell migration);GO:0031103(axon regeneration);GO:0031643(positive regulation of myelination);GO:0033268(node of Ranvier);GO:0034399(nuclear periphery);GO:0034453(microtubule anchoring);GO:0042169(SH2 domain binding);GO:0042383(sarcolemma);GO:0043034(costamere);GO:0043236(laminin binding);GO:0043237(laminin-1 binding);GO:0043403(skeletal muscle tissue regeneration);GO:0043409(negative regulation of MAPK cascade);GO:0043434(response to peptide hormone);GO:0044853(plasma membrane raft);GO:0045121(membrane raft);GO:0045202(synapse);GO:0045211(postsynaptic membrane);GO:0045860(positive regulation of protein kinase activity);GO:0046718(viral entry into host cell);GO:0048714(positive regulation of oligodendrocyte differentiation);GO:0050807(regulation of synapse organization);GO:0051393(alpha-actinin binding);GO:0051898(negative regulation of protein kinase B signaling);GO:0060055(angiogenesis involved in wound healing);GO:0060441(epithelial tube branching involved in lung morphogenesis);GO:0060445(branching involved in salivary gland morphogenesis);GO:0062023(collagen-containing extracellular matrix);GO:0070062(extracellular exosome);GO:0070938(contractile ring);GO:0071260(cellular response to mechanical stimulus);GO:0071397(cellular response to cholesterol);GO:0071679(commissural neuron axon guidance);GO:0071711(basement membrane organization);GO:0098696(regulation of neurotransmitter receptor localization to postsynaptic specialization membrane);GO:0098942(retrograde trans-synaptic signaling by trans-synaptic protein complex);GO:0098978(glutamatergic synapse);GO:0098982(GABA-ergic synapse);GO:0099524(postsynaptic cytosol);GO:1904261(positive regulation of basement membrane assembly involved in embryonic body morphogenesis)","04512(ECM-receptor interaction);05410(Hypertrophic cardiomyopathy (HCM));05412(Arrhythmogenic right ventricular cardiomyopathy (ARVC));05414(Dilated cardiomyopathy (DCM));05416(Viral myocarditis)","NA","NA","dystroglycan 1 [Source:HGNC Symbol;Acc:HGNC:2666]",{"v":0.004519,"d":"0.00"},0,{"v":0.014997,"d":"0.01"},{"v":0.014854,"d":"0.01"},{"v":0.003393,"d":"0.00"},{"v":0.016352,"d":"0.02"},{"v":0.564062545160265,"d":"0.56"},{"v":-0.826072952494397,"d":"-0.83"},1,1,"down","no"]
[100335,0,"chr19","+",16076073,16102969,"ENST00000642789",9,2431,"ENSG00000167460","TPM4","GO:0001649(osteoblast differentiation);GO:0001725(stress fiber);GO:0002102(podosome);GO:0003779(actin binding);GO:0005509(calcium ion binding);GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005856(cytoskeleton);GO:0005862(muscle thin filament tropomyosin);GO:0005884(actin filament);GO:0005925(focal adhesion);GO:0006936(muscle contraction);GO:0007015(actin filament organization);GO:0008307(structural constituent of muscle);GO:0015629(actin cytoskeleton);GO:0016020(membrane);GO:0030049(muscle filament sliding);GO:0030863(cortical cytoskeleton);GO:0042802(identical protein binding);GO:0042803(protein homodimerization activity);GO:0046872(metal ion binding);GO:0046982(protein heterodimerization activity);GO:0051015(actin filament binding);GO:0070062(extracellular exosome)","04260(Cardiac muscle contraction);04261(Adrenergic signaling in cardiomyocytes);05410(Hypertrophic cardiomyopathy (HCM));05414(Dilated cardiomyopathy (DCM))","K10375","NA","tropomyosin 4 [Source:HGNC Symbol;Acc:HGNC:12013]",{"v":8e-6,"d":"0.00"},0,0,0,0,0,"inf","inf",1,1,"up","no"]
[14219,0,"chr1","-",175010789,175014824,"ENST00000498253",3,539,"ENSG00000120333","MRPS14","GO:0003723(RNA binding);GO:0003735(structural constituent of ribosome);GO:0005622(intracellular);GO:0005739(mitochondrion);GO:0005743(mitochondrial inner membrane);GO:0005761(mitochondrial ribosome);GO:0005763(mitochondrial small ribosomal subunit);GO:0005840(ribosome);GO:0006412(translation);GO:0070125(mitochondrial translational elongation);GO:0070126(mitochondrial translational termination)","03010(Ribosome)","K02954","NA","mitochondrial ribosomal protein S14 [Source:HGNC Symbol;Acc:HGNC:14049]",{"v":0.186562,"d":"0.19"},{"v":0.053751,"d":"0.05"},{"v":0.116962,"d":"0.12"},0,{"v":0.217296,"d":"0.22"},{"v":0.07411,"d":"0.07"},{"v":1.22603858534141,"d":"1.23"},{"v":0.294004383600258,"d":"0.29"},1,1,"up","no"]
[70517,0,"chr16","+",3056794,3058306,"ENST00000575441",4,710,"ENSG00000008516","MMP25","GO:0004222(metalloendopeptidase activity);GO:0005576(extracellular region);GO:0005615(extracellular space);GO:0005886(plasma membrane);GO:0006508(proteolysis);GO:0006954(inflammatory response);GO:0008233(peptidase activity);GO:0008237(metallopeptidase activity);GO:0008270(zinc ion binding);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016787(hydrolase activity);GO:0030198(extracellular matrix organization);GO:0030574(collagen catabolic process);GO:0031012(extracellular matrix);GO:0031225(anchored component of membrane);GO:0035579(specific granule membrane);GO:0043312(neutrophil degranulation);GO:0046872(metal ion binding);GO:0060022(hard palate development)","04928(Parathyroid hormone synthesis, secretion and action)","K08003","EC:3.4.24.-","matrix metallopeptidase 25 [Source:HGNC Symbol;Acc:HGNC:14246]",0,{"v":0.053089,"d":"0.05"},{"v":0.326418,"d":"0.33"},{"v":0.133652,"d":"0.13"},0,0,{"v":2.83951605662467,"d":"2.84"},{"v":1.50564506980021,"d":"1.51"},1,1,"up","no"]
[167645,0,"chr6","+",17393732,17539290,"ENST00000476263",9,891,"ENSG00000112186","CAP2","GO:0000902(cell morphogenesis);GO:0003779(actin binding);GO:0005515(protein binding);GO:0005886(plasma membrane);GO:0007010(cytoskeleton organization);GO:0007163(establishment or maintenance of cell polarity);GO:0007165(signal transduction);GO:0007190(activation of adenylate cyclase activity);GO:0008154(actin polymerization or depolymerization);GO:0008179(adenylate cyclase binding);GO:0014069(postsynaptic density);GO:0016020(membrane);GO:0030864(cortical actin cytoskeleton);GO:0042802(identical protein binding)","NA","K17261","NA","cyclase associated actin cytoskeleton regulatory protein 2 [Source:HGNC Symbol;Acc:HGNC:20039]",0,0,0,0,0,{"v":0.04277,"d":"0.04"},"-inf","-inf",1,1,"down","no"]
[148483,0,"chr3","-",196055111,196060604,"ENST00000483983",4,757,"ENSG00000072274","TFRC","GO:0001618(virus receptor activity);GO:0003723(RNA binding);GO:0003725(double-stranded RNA binding);GO:0004998(transferrin receptor activity);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0005615(extracellular space);GO:0005768(endosome);GO:0005769(early endosome);GO:0005886(plasma membrane);GO:0005887(integral component of plasma membrane);GO:0005905(clathrin-coated pit);GO:0006826(iron ion transport);GO:0006879(cellular iron ion homeostasis);GO:0006897(endocytosis);GO:0006898(receptor-mediated endocytosis);GO:0009897(external side of plasma membrane);GO:0009986(cell surface);GO:0010008(endosome membrane);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016032(viral process);GO:0016323(basolateral plasma membrane);GO:0030316(osteoclast differentiation);GO:0030665(clathrin-coated vesicle membrane);GO:0030890(positive regulation of B cell proliferation);GO:0031410(cytoplasmic vesicle);GO:0031623(receptor internalization);GO:0033570(transferrin transmembrane transporter activity);GO:0033572(transferrin transport);GO:0035690(cellular response to drug);GO:0042102(positive regulation of T cell proliferation);GO:0042470(melanosome);GO:0042802(identical protein binding);GO:0042803(protein homodimerization activity);GO:0045780(positive regulation of bone resorption);GO:0045830(positive regulation of isotype switching);GO:0046718(viral entry into host cell);GO:0048471(perinuclear region of cytoplasm);GO:0055037(recycling endosome);GO:0061024(membrane organization);GO:0070062(extracellular exosome);GO:0072562(blood microparticle);GO:1903561(extracellular vesicle);GO:1990712(HFE-transferrin receptor complex);GO:1990830(cellular response to leukemia inhibitory factor)","04066(HIF-1 signaling pathway);04144(Endocytosis);04145(Phagosome);04216(Ferroptosis);04640(Hematopoietic cell lineage)","K06503","NA","transferrin receptor [Source:HGNC Symbol;Acc:HGNC:11763]",{"v":0.001678,"d":"0.00"},{"v":0.001139,"d":"0.00"},{"v":0.446279,"d":"0.45"},{"v":0.002022,"d":"0.00"},{"v":0.581383,"d":"0.58"},{"v":0.089868,"d":"0.09"},{"v":0.667034026316219,"d":"0.67"},{"v":-0.584167737756986,"d":"-0.58"},1,1,"down","no"]
[204586,0,"chrX","+",78747709,78756404,"ENST00000614823",5,2155,"ENSG00000147145","LPAR4","GO:0004930(G protein-coupled receptor activity);GO:0005886(plasma membrane);GO:0005887(integral component of plasma membrane);GO:0007165(signal transduction);GO:0007186(G protein-coupled receptor signaling pathway);GO:0008289(lipid binding);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016604(nuclear body);GO:0035025(positive regulation of Rho protein signal transduction);GO:0035727(lysophosphatidic acid binding);GO:0043231(intracellular membrane-bounded organelle);GO:0051482(positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway);GO:0070915(lysophosphatidic acid receptor activity)","04015(Rap1 signaling pathway);04072(Phospholipase D signaling pathway);04080(Neuroactive ligand-receptor interaction);04151(PI3K-Akt signaling pathway);04810(Regulation of actin cytoskeleton);05200(Pathways in cancer)","NA","NA","lysophosphatidic acid receptor 4 [Source:HGNC Symbol;Acc:HGNC:4478]",0,{"v":0.408024,"d":"0.41"},{"v":0.166027,"d":"0.17"},{"v":0.16515,"d":"0.17"},{"v":0.208805,"d":"0.21"},{"v":0.250234,"d":"0.25"},{"v":0.919674970241385,"d":"0.92"},{"v":-0.120804018145243,"d":"-0.12"},1,1,"down","no"]
[102604,0,"chr19","+",35545652,35546284,"ENST00000596232",2,562,"ENSG00000105677","TMEM147","GO:0005515(protein binding);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0032991(protein-containing complex)","NA","NA","NA","transmembrane protein 147 [Source:HGNC Symbol;Acc:HGNC:30414]",{"v":0.326161,"d":"0.33"},{"v":0.39937,"d":"0.40"},{"v":0.005636,"d":"0.01"},{"v":0.542568,"d":"0.54"},{"v":0.196319,"d":"0.20"},{"v":0.162302,"d":"0.16"},{"v":0.811335912888417,"d":"0.81"},{"v":-0.301628745768844,"d":"-0.30"},1,1,"down","no"]
[130092,0,"chr21","-",34446690,34459604,"ENST00000399289",3,3154,"ENSG00000180509","KCNE1","GO:0005244(voltage-gated ion channel activity);GO:0005249(voltage-gated potassium channel activity);GO:0005251(delayed rectifier potassium channel activity);GO:0005267(potassium channel activity);GO:0005515(protein binding);GO:0005764(lysosome);GO:0005886(plasma membrane);GO:0006811(ion transport);GO:0006813(potassium ion transport);GO:0007605(sensory perception of sound);GO:0008076(voltage-gated potassium channel complex);GO:0009986(cell surface);GO:0015459(potassium channel regulator activity);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016324(apical plasma membrane);GO:0030018(Z disc);GO:0031433(telethonin binding);GO:0034765(regulation of ion transmembrane transport);GO:0044325(ion channel binding);GO:0045121(membrane raft);GO:0060307(regulation of ventricular cardiac muscle cell membrane repolarization);GO:0061337(cardiac conduction);GO:0071320(cellular response to cAMP);GO:0071805(potassium ion transmembrane transport);GO:0086002(cardiac muscle cell action potential involved in contraction);GO:0086005(ventricular cardiac muscle cell action potential);GO:0086008(voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization);GO:0086009(membrane repolarization);GO:0086011(membrane repolarization during action potential);GO:0086013(membrane repolarization during cardiac muscle cell action potential);GO:0086091(regulation of heart rate by cardiac conduction);GO:0090315(negative regulation of protein targeting to membrane);GO:0097623(potassium ion export across plasma membrane);GO:0098915(membrane repolarization during ventricular cardiac muscle cell action potential);GO:1901379(regulation of potassium ion transmembrane transport);GO:1901381(positive regulation of potassium ion transmembrane transport);GO:1902259(regulation of delayed rectifier potassium channel activity);GO:1902260(negative regulation of delayed rectifier potassium channel activity);GO:1902282(voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization)","04261(Adrenergic signaling in cardiomyocytes)","NA","NA","potassium voltage-gated channel subfamily E regulatory subunit 1 [Source:HGNC Symbol;Acc:HGNC:6240]",0,0,0,0,0,0,1,0,1,1,"no","no"]
[179466,0,"chr7","+",64469185,64470653,"ENST00000436625",1,1469,"ENSG00000228014","ZNF680P1","NA","NA","NA","NA","ZNF680 pseudogene 1 [Source:HGNC Symbol;Acc:HGNC:50379]",0,0,0,0,0,0,1,0,1,1,"no","no"]
[152923,0,"chr4","-",86016486,86360089,"ENST00000641537",13,2623,"ENSG00000109339","MAPK10","GO:0000122(negative regulation of transcription by RNA polymerase II);GO:0000165(MAPK cascade);GO:0000166(nucleotide binding);GO:0000187(activation of MAPK activity);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0004705(JUN kinase activity);GO:0004707(MAP kinase activity);GO:0004708(MAP kinase kinase activity);GO:0005515(protein binding);GO:0005524(ATP binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0005739(mitochondrion);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0006468(protein phosphorylation);GO:0007165(signal transduction);GO:0007254(JNK cascade);GO:0007258(JUN phosphorylation);GO:0009414(response to water deprivation);GO:0009416(response to light stimulus);GO:0010468(regulation of gene expression);GO:0016020(membrane);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0016740(transferase activity);GO:0035556(intracellular signal transduction);GO:0038095(Fc-epsilon receptor signaling pathway);GO:0042752(regulation of circadian rhythm);GO:0043005(neuron projection);GO:0043204(perikaryon);GO:0048511(rhythmic process);GO:0051090(regulation of DNA-binding transcription factor activity);GO:0071310(cellular response to organic substance);GO:0071474(cellular hyperosmotic response);GO:0098969(neurotransmitter receptor transport to postsynaptic membrane);GO:0098978(glutamatergic synapse);GO:0099003(vesicle-mediated transport in synapse)","01522(Endocrine resistance);04010(MAPK signaling pathway);04012(ErbB signaling pathway);04014(Ras signaling pathway);04024(cAMP signaling pathway);04068(FoxO signaling pathway);04071(Sphingolipid signaling pathway);04137(Mitophagy - animal);04140(Autophagy - animal);04141(Protein processing in endoplasmic reticulum);04210(Apoptosis);04215(Apoptosis - multiple species);04217(Necroptosis);04310(Wnt signaling pathway);04380(Osteoclast differentiation);04510(Focal adhesion);04530(Tight junction);04620(Toll-like receptor signaling pathway);04621(NOD-like receptor signaling pathway);04622(RIG-I-like receptor signaling pathway);04625(C-type lectin receptor signaling pathway);04657(IL-17 signaling pathway);04658(Th1 and Th2 cell differentiation);04659(Th17 cell differentiation);04664(Fc epsilon RI signaling pathway);04668(TNF signaling pathway);04722(Neurotrophin signaling pathway);04723(Retrograde endocannabinoid signaling);04728(Dopaminergic synapse);04750(Inflammatory mediator regulation of TRP channels);04910(Insulin signaling pathway);04912(GnRH signaling pathway);04914(Progesterone-mediated oocyte maturation);04917(Prolactin signaling pathway);04920(Adipocytokine signaling pathway);04926(Relaxin signaling pathway);04930(Type II diabetes mellitus);04931(Insulin resistance);04932(Non-alcoholic fatty liver disease (NAFLD));04933(AGE-RAGE signaling pathway in diabetic complications);05120(Epithelial cell signaling in Helicobacter pylori infection);05131(Shigellosis);05132(Salmonella infection);05133(Pertussis);05142(Chagas disease (American trypanosomiasis));05145(Toxoplasmosis);05152(Tuberculosis);05161(Hepatitis B);05162(Measles);05164(Influenza A);05166(Human T-cell leukemia virus 1 infection);05167(Kaposi sarcoma-associated herpesvirus infection);05169(Epstein-Barr virus infection);05170(Human immunodeficiency virus 1 infection);05200(Pathways in cancer);05210(Colorectal cancer);05212(Pancreatic cancer);05231(Choline metabolism in cancer);05418(Fluid shear stress and atherosclerosis)","K04440","EC:2.7.11.24","mitogen-activated protein kinase 10 [Source:HGNC Symbol;Acc:HGNC:6872]",0,0,0,0,0,0,1,0,1,1,"no","no"]
[123004,0,"chr2","+",231041107,231049719,"ENST00000463834",2,3141,"ENSG00000204128","C2orf72","NA","NA","NA","NA","chromosome 2 open reading frame 72 [Source:HGNC Symbol;Acc:HGNC:27418]",{"v":0.013368,"d":"0.01"},0,0,0,0,0,"inf","inf",1,1,"up","no"]
[65812,0,"chr15","-",69282963,69298758,"ENST00000565312",4,1934,"ENSG00000261634","AC026992","NA","NA","NA","NA","novel transcript, antisense to PAQR5",{"v":0.018387,"d":"0.02"},0,0,0,0,{"v":0.045855,"d":"0.05"},{"v":0.400981354268891,"d":"0.40"},{"v":-1.31839294231995,"d":"-1.32"},1,1,"down","no"]
[37396,0,"chr11","+",121024125,121110722,"ENST00000644541",10,2851,"ENSG00000285509","AP000646","GO:0007160(cell-matrix adhesion)","NA","NA","NA","novel protein",{"v":0.059869,"d":"0.06"},{"v":0.146533,"d":"0.15"},{"v":0.120905,"d":"0.12"},{"v":0.027244,"d":"0.03"},{"v":0.069079,"d":"0.07"},{"v":0.115711,"d":"0.12"},{"v":1.5436533763453,"d":"1.54"},{"v":0.626348835268887,"d":"0.63"},1,1,"up","no"]
[76994,0,"chr16","+",69838737,69941741,"ENST00000356003",21,4227,"ENSG00000198373","WWP2","GO:0000122(negative regulation of transcription by RNA polymerase II);GO:0000151(ubiquitin ligase complex);GO:0000209(protein polyubiquitination);GO:0001085(RNA polymerase II transcription factor binding);GO:0004842(ubiquitin-protein transferase activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0006464(cellular protein modification process);GO:0006511(ubiquitin-dependent protein catabolic process);GO:0006858(extracellular transport);GO:0008134(transcription factor binding);GO:0010629(negative regulation of gene expression);GO:0016020(membrane);GO:0016032(viral process);GO:0016567(protein ubiquitination);GO:0016740(transferase activity);GO:0016874(ligase activity);GO:0032410(negative regulation of transporter activity);GO:0034765(regulation of ion transmembrane transport);GO:0042391(regulation of membrane potential);GO:0043161(proteasome-mediated ubiquitin-dependent protein catabolic process);GO:0043433(negative regulation of DNA-binding transcription factor activity);GO:0045732(positive regulation of protein catabolic process);GO:0045746(negative regulation of Notch signaling pathway);GO:0045892(negative regulation of transcription, DNA-templated);GO:0045944(positive regulation of transcription by RNA polymerase II);GO:0046718(viral entry into host cell);GO:0051224(negative regulation of protein transport);GO:0051865(protein autoubiquitination);GO:0061630(ubiquitin protein ligase activity);GO:0070062(extracellular exosome);GO:0070534(protein K63-linked ubiquitination);GO:1901016(regulation of potassium ion transmembrane transporter activity)","04120(Ubiquitin mediated proteolysis)","K05630","EC:2.3.2.26","WW domain containing E3 ubiquitin protein ligase 2 [Source:HGNC Symbol;Acc:HGNC:16804]",0,0,0,0,0,0,1,0,1,1,"no","no"]
[205226,0,"chrX","+",103962641,103966712,"ENST00000563257",3,590,"ENSG00000158427","TMSB15B","GO:0000981(DNA-binding transcription factor activity, RNA polymerase II-specific);GO:0003674(molecular_function);GO:0003779(actin binding);GO:0003785(actin monomer binding);GO:0005575(cellular_component);GO:0005737(cytoplasm);GO:0005856(cytoskeleton);GO:0006357(regulation of transcription by RNA polymerase II);GO:0007015(actin filament organization);GO:0030334(regulation of cell migration);GO:0030335(positive regulation of cell migration);GO:0042989(sequestering of actin monomers)","NA","NA","NA","thymosin beta 15B [Source:HGNC Symbol;Acc:HGNC:28612]",0,0,0,{"v":0.06439,"d":"0.06"},0,0,"-inf","-inf",1,1,"down","no"]
[111953,0,"chr2","+",44362105,44401145,"ENST00000454433",7,843,"ENSG00000143919","CAMKMT","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005794(Golgi apparatus);GO:0005829(cytosol);GO:0006479(protein methylation);GO:0007005(mitochondrion organization);GO:0008168(methyltransferase activity);GO:0016740(transferase activity);GO:0018022(peptidyl-lysine methylation);GO:0018025(calmodulin-lysine N-methyltransferase activity);GO:0022400(regulation of rhodopsin mediated signaling pathway);GO:0031072(heat shock protein binding);GO:0032259(methylation);GO:0032991(protein-containing complex)","00310(Lysine degradation)","K18826","EC:2.1.1.60","calmodulin-lysine N-methyltransferase [Source:HGNC Symbol;Acc:HGNC:26276]",0,0,{"v":0.02053,"d":"0.02"},0,0,0,"inf","inf",1,1,"up","no"]
[1478,0,"chr1","-",10647213,10796650,"ENST00000344008",16,4405,"ENSG00000130940","CASZ1","GO:0000981(DNA-binding transcription factor activity, RNA polymerase II-specific);GO:0003676(nucleic acid binding);GO:0003677(DNA binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0006355(regulation of transcription, DNA-templated);GO:0006357(regulation of transcription by RNA polymerase II);GO:0007275(multicellular organism development);GO:0043231(intracellular membrane-bounded organelle);GO:0045893(positive regulation of transcription, DNA-templated);GO:0046872(metal ion binding)","NA","NA","NA","castor zinc finger 1 [Source:HGNC Symbol;Acc:HGNC:26002]",0,{"v":0.008651,"d":"0.01"},0,0,0,0,"inf","inf",1,1,"up","no"]
[1059,0,"chr1","-",6264269,6393361,"ENST00000608083",9,1403,"ENSG00000097021","ACOT7","GO:0000062(fatty-acyl-CoA binding);GO:0005515(protein binding);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0005739(mitochondrion);GO:0005829(cytosol);GO:0006637(acyl-CoA metabolic process);GO:0015937(coenzyme A biosynthetic process);GO:0016290(palmitoyl-CoA hydrolase activity);GO:0016787(hydrolase activity);GO:0016790(thiolester hydrolase activity);GO:0036042(long-chain fatty acyl-CoA binding);GO:0036114(medium-chain fatty-acyl-CoA catabolic process);GO:0036116(long-chain fatty-acyl-CoA catabolic process);GO:0042803(protein homodimerization activity);GO:0047617(acyl-CoA hydrolase activity);GO:0051792(medium-chain fatty acid biosynthetic process);GO:0052689(carboxylic ester hydrolase activity);GO:0070062(extracellular exosome);GO:0102991(myristoyl-CoA hydrolase activity);GO:1900535(palmitic acid biosynthetic process)","00062(Fatty acid elongation);01040(Biosynthesis of unsaturated fatty acids)","K17360","EC:3.1.2.2","acyl-CoA thioesterase 7 [Source:HGNC Symbol;Acc:HGNC:24157]",{"v":0.075696,"d":"0.08"},{"v":0.062361,"d":"0.06"},{"v":0.048967,"d":"0.05"},{"v":7.671571,"d":"7.67"},{"v":0.13805,"d":"0.14"},{"v":0.06103,"d":"0.06"},{"v":0.0237622021355031,"d":"0.02"},{"v":-5.39518764729125,"d":"-5.40"},1,1,"down","no"]
[104817,0,"chr19","-",43766533,43781257,"ENST00000615047",10,2029,"ENSG00000104783","KCNN4","GO:0002376(immune system process);GO:0005267(potassium channel activity);GO:0005515(protein binding);GO:0005516(calmodulin binding);GO:0005886(plasma membrane);GO:0006811(ion transport);GO:0006813(potassium ion transport);GO:0006816(calcium ion transport);GO:0006884(cell volume homeostasis);GO:0006952(defense response);GO:0008076(voltage-gated potassium channel complex);GO:0015269(calcium-activated potassium channel activity);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016286(small conductance calcium-activated potassium channel activity);GO:0019903(protein phosphatase binding);GO:0022894(Intermediate conductance calcium-activated potassium channel activity);GO:0030322(stabilization of membrane potential);GO:0031982(vesicle);GO:0043005(neuron projection);GO:0043025(neuronal cell body);GO:0045332(phospholipid translocation);GO:0046541(saliva secretion);GO:0050714(positive regulation of protein secretion);GO:0050862(positive regulation of T cell receptor signaling pathway);GO:0071805(potassium ion transmembrane transport)","04911(Insulin secretion);04970(Salivary secretion);04974(Protein digestion and absorption)","K04945","NA","potassium calcium-activated channel subfamily N member 4 [Source:HGNC Symbol;Acc:HGNC:6293]",{"v":0.14472,"d":"0.14"},0,0,{"v":0.153913,"d":"0.15"},0,{"v":0.27541,"d":"0.28"},{"v":0.337088858505135,"d":"0.34"},{"v":-1.56879915087887,"d":"-1.57"},1,1,"down","no"]
[185927,0,"chr7","-",158733613,158744217,"ENST00000435514",7,2090,"ENSG00000117868","ESYT2","GO:0005509(calcium ion binding);GO:0005515(protein binding);GO:0005544(calcium-dependent phospholipid binding);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005886(plasma membrane);GO:0005887(integral component of plasma membrane);GO:0006687(glycosphingolipid metabolic process);GO:0006869(lipid transport);GO:0006897(endocytosis);GO:0008289(lipid binding);GO:0008429(phosphatidylethanolamine binding);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0031210(phosphatidylcholine binding);GO:0031227(intrinsic component of endoplasmic reticulum membrane);GO:0031234(extrinsic component of cytoplasmic side of plasma membrane);GO:0035091(phosphatidylinositol binding);GO:0042802(identical protein binding);GO:0044232(organelle membrane contact site);GO:0045296(cadherin binding);GO:0046872(metal ion binding);GO:0061817(endoplasmic reticulum-plasma membrane tethering);GO:0140268(endoplasmic reticulum-plasma membrane contact site)","NA","NA","NA","extended synaptotagmin 2 [Source:HGNC Symbol;Acc:HGNC:22211]",{"v":0.077379,"d":"0.08"},{"v":0.031059,"d":"0.03"},{"v":0.496894,"d":"0.50"},{"v":0.266665,"d":"0.27"},{"v":0.072373,"d":"0.07"},{"v":0.023656,"d":"0.02"},{"v":1.66898818287592,"d":"1.67"},{"v":0.738973739861291,"d":"0.74"},1,1,"up","no"]