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{"sheet":"3D_2D.fpkm.anno","index":0,"n_rows":234,"n_cols":40,"rows_kept":234}
["Gene","3D_count","3D_fpkm","3D_normalize","2D_count","2D_fpkm","2D_normalize","FoldChange","Log2FoldChange","pval","padj","Up/Down","Significant","GeneName","Biotype","Position","NR:Seq-id","NR:Score","NR:Evalue","NR:Description","NT:Seq-id","NT:Score","NT:Evalue","NT:Description","Uniprot:UniProtKB-AC","Uniprot:Score","Uniprot:Evalue","Uniprot:Description","COG:gene","COG:Score","COG:Eval","COG:num","Pfam:pfam_ID","Pfam:pfam_Name","Pfam:pfam_Description","GO:biological_process","GO:cellular_component","GO:molecular_function","KEGG:KO","KEGG:Description"]
["ENSRNOG00000065394",1693,53.3087611595874,142.441009818417,230,7.14675595835658,19.0961319207288,7.45915510060957,2.89901222549495,{"v":5.77567360122896e-276,"d":"5.78E-276"},{"v":1.90647684267322e-273,"d":"1.91E-273"},"up","yes","ENSRNOG00000065394","lncRNA","chr1:31564-36478:+","gi|149066342|gb|EDM16215.1|",297,{"v":1E-26,"d":"1.00E-26"},"rCG59713 [Rattus norvegicus]","gi|14389324|gb|AC087775.2|",859,0,"Rattus norvegicus strain Brown Norway clone RP31-464J4, complete sequence","Q4VAE3",117,{"v":1E-27,"d":"1.00E-27"},"Transmembrane protein 65",".",".",".",".","pfam10507","DUF2453","Protein of unknown function (DUF2453). Some members of this family are purported to contain GAF domains but this could not be confirmed. The function is not known. It is likely to be a transmembrane protein.",".",".",".",".","."]
["ENSRNOG00000013279",1210,29.5940915878455,101.803675062188,181,4.36855394040939,15.0278255550083,6.77434501016419,2.76008146362243,{"v":2.81987158234037e-188,"d":"2.82E-188"},{"v":5.74325848872408e-186,"d":"5.74E-186"},"up","yes","ENSRNOG00000013279","protein_coding","chr1:243078774-243114229:+","gi|672014957|ref|XP_008773072.1|",1789,0,"PREDICTED: acyl-CoA desaturase 1-like [Rattus norvegicus]","gi|672014956|ref|XM_008774850.1|",1268,0,"PREDICTED: Rattus norvegicus similar to stearoyl-coenzyme A desaturase 3 (LOC681458), mRNA","Q99PL7",661,0,"Acyl-CoA desaturase 3","SPCC1281.06c_1",205,{"v":4e-57,"d":"4.00E-57"},"COG1398","pfam00487","FA_desaturase","Fatty acid desaturase.","GO:0006636|unsaturated fatty acid biosynthetic process;GO:0070542|response to fatty acid;GO:1903966|monounsaturated fatty acid biosynthetic process;","GO:0005789|endoplasmic reticulum membrane;GO:0030176|integral component of endoplasmic reticulum membrane;","GO:0004768|stearoyl-CoA 9-desaturase activity;GO:0005506|iron ion binding;GO:0032896|palmitoyl-CoA 9-desaturase activity;","K00507","SCD, desC; stearoyl-CoA desaturase (Delta-9 desaturase) [EC:1.14.19.1]"]
["ENSRNOG00000011754",1340,21.0338171616092,112.741259986225,236,3.6556514708728,19.5942918838782,5.75378077729802,2.52451025452698,{"v":2.92193851843894e-189,"d":"2.92E-189"},{"v":6.08051175033239e-187,"d":"6.08E-187"},"up","yes","Myom2","protein_coding","chr16:74520157-74592772:-","gi|281306803|ref|NP_001162612.1|",7610,0,"myomesin-2 [Rattus norvegicus]","gi|672080527|ref|XM_006253389.2|",4896,0,"PREDICTED: Rattus norvegicus myomesin 2 (Myom2), transcript variant X1, mRNA","P54296",2676,0,"Myomesin-2",".",".",".",".","pfam07679","I-set","Immunoglobulin I-set domain.","GO:0002074|extraocular skeletal muscle development;GO:0006936|muscle contraction;GO:0045214|sarcomere organization;","GO:0031430|M band;","GO:0019900|kinase binding;GO:0051015|actin filament binding;","K24495","MYOM; myomesin"]
["ENSRNOG00000018028",911,56.192983678082,76.6472297369039,162,9.86093768697585,13.450319005035,5.69854363366485,2.51059325946111,{"v":1.58486953534329e-128,"d":"1.58E-128"},{"v":2.16731665097835e-126,"d":"2.17E-126"},"up","yes","Testin","protein_coding","chr17:3846899-3859385:+","gi|27465595|ref|NP_775155.1|",1819,0,"testin-2 precursor [Rattus norvegicus]","gi|402693052|ref|NM_173132.2|",1358,0,"Rattus norvegicus testin gene (Testin), mRNA","P15242",705,0,"Testin-2","AF1946_2",72,{"v":2e-13,"d":"2.00E-13"},"COG4870","pfam00112","Peptidase_C1","Papain family cysteine protease.","GO:0006955|immune response;GO:0051603|proteolysis involved in cellular protein catabolic process;","GO:0005615|extracellular space;GO:0005764|lysosome;GO:0030054|cell junction;","GO:0004197|cysteine-type endopeptidase activity;","K24271","Testin; testin-2"]
["ENSRNOG00000030210",719,9.39190469752959,60.493258156788,149,1.92066021086962,12.3709724182112,4.88993557755703,2.28981545852082,{"v":1.16425412269357E-91,"d":"1.16E-91"},{"v":1.05140202566E-89,"d":"1.05E-89"},"up","yes","Fndc1","protein_coding","chr1:47281844-47364259:+","gi|564325199|ref|XP_006227933.1|",5986,0,"PREDICTED: fibronectin type III domain-containing protein 1 isoform X1 [Rattus norvegicus]","gi|672034288|ref|XM_006227871.2|",6335,0,"PREDICTED: Rattus norvegicus fibronectin type III domain containing 1 (Fndc1), transcript variant X1, mRNA","Q2Q0I9",2176,0,"Fibronectin type III domain-containing protein 1",".",".",".",".","pfam00041","fn3","Fibronectin type III domain.","GO:0001934|positive regulation of protein phosphorylation;GO:0010666|positive regulation of cardiac muscle cell apoptotic process;GO:0051223|regulation of protein transport;GO:0071456|cellular response to hypoxia;","GO:0005576|extracellular region;GO:0005737|cytoplasm;GO:0005886|plasma membrane;GO:0005911|cell-cell junction;GO:0016607|nuclear speck;GO:0031966|mitochondrial membrane;",".","K24484","FNDC1; fibronectin type III domain-containing protein 1"]
["ENSRNOG00000008000",1501,37.3188647276305,126.287038238301,326,7.99843124442078,27.066691331119898,4.66577302313648,2.2221161259333,{"v":1.76556529074946E-182,"d":"1.77E-182"},{"v":3.44916994084841E-180,"d":"3.45E-180"},"up","yes","Syt13","protein_coding","chr3:78877114-78917392:+","gi|11119239|gb|AAG30575.1|AF313453_1",1852,0,"synaptotagmin 13 [Rattus norvegicus]","gi|672046319|ref|XM_008762036.1|",3118,0,"PREDICTED: Rattus norvegicus synaptotagmin XIII (Syt13), transcript variant X1, mRNA","Q925B5",717,0,"Synaptotagmin-13",".",".",".",".","pfam00168","C2","C2 domain.","GO:0006906|vesicle fusion;GO:0014059|regulation of dopamine secretion;GO:0016192|vesicle-mediated transport;GO:0017156|calcium ion regulated exocytosis;GO:0017158|regulation of calcium ion-dependent exocytosis;GO:0071277|cellular response to calcium ion;","GO:0005886|plasma membrane;GO:0005887|integral component of plasma membrane;GO:0030133|transport vesicle;GO:0030424|axon;GO:0043231|intracellular membrane-bounded organelle;GO:0045202|synapse;GO:0070382|exocytic vesicle;","GO:0000149|SNARE binding;GO:0001786|phosphatidylserine binding;GO:0005509|calcium ion binding;GO:0005544|calcium-dependent phospholipid binding;GO:0030276|clathrin binding;","K19913","SYT13; synaptotagmin-13"]
["ENSRNOG00000005964",571,8.7858885144688,48.0412383971154,132,2.00430124164005,10.9595191892878,4.38351697436438,2.13208883454807,{"v":3.61136225737639e-67,"d":"3.61E-67"},{"v":2.32012656490893e-65,"d":"2.32E-65"},"up","yes","Nr4a3","protein_coding","chr5:62361822-62402733:+","gi|672052568|ref|XP_008761925.1|",2752,0,"PREDICTED: nuclear receptor subfamily 4 group A member 3 isoform X2 [Rattus norvegicus]","gi|82393808|gb|DQ268830.1|",5368,0,"Rattus norvegicus neuron-derived orphan receptor 1 mRNA, complete cds","P51179",1009,0,"Nuclear receptor subfamily 4 group A member 3",".",".",".",".","pfam00105","zf-C4","Zinc finger, C4 type (two domains). In nearly all cases, this is the DNA binding domain of a nuclear hormone receptor. The alignment contains two Zinc finger domains that are too dissimilar to be aligned with each other.","GO:0000122|negative regulation of transcription by RNA polymerase II;GO:0001707|mesoderm formation;GO:0006357|regulation of transcription by RNA polymerase II;GO:0007369|gastrulation;GO:0007411|axon guidance;GO:0009444|pyruvate oxidation;GO:0010613|positive regulation of cardiac muscle hypertrophy;GO:0010828|positive regulation of glucose transmembrane transport;GO:0021766|hippocampus development;GO:0030522|intracellular receptor signaling pathway;GO:0030534|adult behavior;GO:0031100|animal organ regeneration;GO:0032765|positive regulation of mast cell cytokine production;GO:0035726|common myeloid progenitor cell proliferation;GO:0038097|positive regulation of mast cell activation by Fc-epsilon receptor signaling pathway;GO:0042472|inner ear morphogenesis;GO:0042542|response to hydrogen peroxide;GO:0043066|negative regulation of apoptotic process;GO:0043303|mast cell degranulation;GO:0043434|response to peptide hormone;GO:0043524|negative regulation of neuron apoptotic process;GO:0044320|cellular response to leptin stimulus;GO:0045333|cellular respiration;GO:0045444|fat cell differentiation;GO:0045787|positive regulation of cell cycle;GO:0045893|positive regulation of transcription, DNA-templated;GO:0045944|positive regulation of transcription by RNA polymerase II;GO:0046321|positive regulation of fatty acid oxidation;GO:0048008|platelet-derived growth factor receptor signaling pathway;GO:0048660|regulation of smooth muscle cell proliferation;GO:0048661|positive regulation of smooth muscle cell proliferation;GO:0048752|semicircular canal morphogenesis;GO:0050679|positive regulation of epithelial cell proliferation;GO:0050885|neuromuscular process controlling balance;GO:0060005|vestibular reflex;GO:0061469|regulation of type B pancreatic cell proliferation;GO:0071376|cellular response to corticotropin-releasing hormone stimulus;GO:0071870|cellular response to catecholamine stimulus;GO:0097009|energy homeostasis;GO:1900625|positive regulation of monocyte aggregation;GO:1903204|negative regulation of oxidative stress-induced neuron death;GO:1903208|negative regulation of hydrogen peroxide-induced neuron death;GO:1904707|positive regulation of vascular smooth muscle cell proliferation;GO:1904754|positive regulation of vascular associated smooth muscle cell migration;GO:2000108|positive regulation of leukocyte apoptotic process;GO:2000253|positive regulation of feeding behavior;","GO:0005575|cellular_component;GO:0005634|nucleus;GO:0005667|transcription factor complex;","GO:0000978|RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0000981|DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001223|transcription coactivator binding;GO:0001228|DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677|DNA binding;GO:0004879|nuclear receptor activity;GO:0005515|protein binding;GO:0008270|zinc ion binding;GO:0019901|protein kinase binding;GO:0035035|histone acetyltransferase binding;GO:0035259|glucocorticoid receptor binding;GO:0035497|cAMP response element binding;GO:0042803|protein homodimerization activity;GO:0043565|sequence-specific DNA binding;","K08559","NR4A3, NOR1; nuclear receptor subfamily 4 group A member 3"]
["ENSRNOG00000018646",474,16.9919545540737,39.880117338411,118,4.17432720150793,9.79714594193912,4.07058520662576,2.0252362180801,{"v":1.29879929810326E-52,"d":"1.30E-52"},{"v":6.37579469589794e-51,"d":"6.38E-51"},"up","yes","Hbegf","protein_coding","chr18:28105760-28116441:-","gi|6978785|ref|NP_037077.1|",844,{"v":3e-104,"d":"3.00E-104"},"proheparin-binding EGF-like growth factor precursor [Rattus norvegicus]","gi|257196256|ref|NM_010415.2|",1685,0,"Mus musculus heparin-binding EGF-like growth factor (Hbegf), mRNA","Q06175",329,{"v":1e-105,"d":"1.00E-105"},"Proheparin-binding EGF-like growth factor",".",".",".",".","pfam00008","EGF","EGF-like domain. There is no clear separation between noise and signal. pfam00053 is very similar, but has 8 instead of 6 conserved cysteines. Includes some cytokine receptors. The EGF domain misses the N-terminus regions of the Ca2+ binding EGF domains (this is the main reason of discrepancy between swiss-prot domain start/end and Pfam). The family is hard to model due to many similar but different sub-types of EGF domains. Pfam certainly misses a number of EGF domains.","GO:0007173|epidermal growth factor receptor signaling pathway;GO:0007399|nervous system development;GO:0008016|regulation of heart contraction;GO:0008284|positive regulation of cell proliferation;GO:0016477|cell migration;GO:0030307|positive regulation of cell growth;GO:0030335|positive regulation of cell migration;GO:0035313|wound healing, spreading of epidermal cells;GO:0045741|positive regulation of epidermal growth factor-activated receptor activity;GO:0048661|positive regulation of smooth muscle cell proliferation;GO:0050731|positive regulation of peptidyl-tyrosine phosphorylation;GO:0051545|negative regulation of elastin biosynthetic process;GO:0051549|positive regulation of keratinocyte migration;GO:0051897|positive regulation of protein kinase B signaling;GO:0060326|cell chemotaxis;GO:0090303|positive regulation of wound healing;","GO:0005615|extracellular space;GO:0005887|integral component of plasma membrane;GO:0009986|cell surface;","GO:0005154|epidermal growth factor receptor binding;GO:0008083|growth factor activity;GO:0008201|heparin binding;","K08523","HBEGF; heparin-binding EGF-like growth factor"]
["ENSRNOG00000064680",1244,50.3193625943112,104.664274196167,310,12.3741657513083,25.7382647627214,4.06648525691445,2.02378238340005,{"v":6.63626650044843e-135,"d":"6.64E-135"},{"v":9.20664966760311e-133,"d":"9.21E-133"},"up","yes","Gpihbp1","protein_coding","chr7:107285654-107288702:+","gi|194474096|ref|NP_001124019.1|",1037,{"v":2e-133,"d":"2.00E-133"},"glycosylphosphatidylinositol-anchored high density lipoprotein-binding protein 1 precursor [Rattus norvegicus]","gi|194474095|ref|NM_001130547.1|",2080,0,"Rattus norvegicus glycosylphosphatidylinositol anchored high density lipoprotein binding protein 1 (Gpihbp1), mRNA","Q9D1N2",318,{"v":6E-102,"d":"6.00E-102"},"Glycosylphosphatidylinositol-anchored high density lipoprotein-binding protein 1",".",".",".",".","pfam15240","Pro-rich","Proline-rich. This family includes several eukaryotic proline-rich proteins.",".",".",".",".","."]
["ENSRNOG00000014692",433,29.6907671751484,36.4305713239071,113,7.64630206953104,9.38201263931458,3.88302304894023,1.95718027085522,{"v":3.49884742700589e-46,"d":"3.50E-46"},{"v":1.54344856432128E-44,"d":"1.54E-44"},"up","yes","Mogat1","protein_coding","chr9:79956649-79988513:+","gi|229577408|ref|NP_080989.2|",1370,0,"2-acylglycerol O-acyltransferase 1 [Mus musculus]","gi|229577407|ref|NM_026713.3|",590,0,"Mus musculus monoacylglycerol O-acyltransferase 1 (Mogat1), mRNA","Q91ZV4",532,0,"2-acylglycerol O-acyltransferase 1",".",".",".",".","pfam03982","DAGAT","Diacylglycerol acyltransferase. The terminal step of triacylglycerol (TAG) formation is catalysed by the enzyme diacylglycerol acyltransferase (DAGAT).","GO:0006629|lipid metabolic process;GO:0006651|diacylglycerol biosynthetic process;GO:0019432|triglyceride biosynthetic process;","GO:0005783|endoplasmic reticulum;GO:0005789|endoplasmic reticulum membrane;GO:0016020|membrane;","GO:0003846|2-acylglycerol O-acyltransferase activity;GO:0004144|diacylglycerol O-acyltransferase activity;GO:0008374|O-acyltransferase activity;","K14458","MOGAT1, MGAT1; 2-acylglycerol O-acyltransferase 1 [EC:2.3.1.22]"]
["ENSRNOG00000005600",451,11.0145155760647,37.945006159543,118,2.84387400346563,9.79714594193912,3.87306735904687,1.95347659243722,{"v":6.50664644677783e-48,"d":"6.51E-48"},{"v":2.93797596291453e-46,"d":"2.94E-46"},"up","yes","Nr4a2","protein_coding","chr3:41689851-41697877:-","gi|803020647|ref|XP_011992369.1|",2767,0,"PREDICTED: nuclear receptor subfamily 4 group A member 2 isoform X2 [Ovis aries]","gi|73476626|gb|DQ092632.1|",1786,0,"Rattus norvegicus nuclear receptor subfamily 4 group A member 2 variant NURR1b (Nr4a2) mRNA, complete cds, alternatively spliced","P43354",1028,0,"Nuclear receptor subfamily 4 group A member 2",".",".",".",".","pfam00105","zf-C4","Zinc finger, C4 type (two domains). In nearly all cases, this is the DNA binding domain of a nuclear hormone receptor. The alignment contains two Zinc finger domains that are too dissimilar to be aligned with each other.","GO:0000122|negative regulation of transcription by RNA polymerase II;GO:0001666|response to hypoxia;GO:0001764|neuron migration;GO:0001975|response to amphetamine;GO:0006351|transcription, DNA-templated;GO:0006355|regulation of transcription, DNA-templated;GO:0006357|regulation of transcription by RNA polymerase II;GO:0007399|nervous system development;GO:0007611|learning or memory;GO:0008344|adult locomotory behavior;GO:0009791|post-embryonic development;GO:0010035|response to inorganic substance;GO:0010467|gene expression;GO:0010468|regulation of gene expression;GO:0017085|response to insecticide;GO:0021952|central nervous system projection neuron axonogenesis;GO:0021953|central nervous system neuron differentiation;GO:0021986|habenula development;GO:0021987|cerebral cortex development;GO:0030182|neuron differentiation;GO:0030522|intracellular receptor signaling pathway;GO:0031668|cellular response to extracellular stimulus;GO:0034599|cellular response to oxidative stress;GO:0042053|regulation of dopamine metabolic process;GO:0042416|dopamine biosynthetic process;GO:0042417|dopamine metabolic process;GO:0042551|neuron maturation;GO:0043085|positive regulation of catalytic activity;GO:0043524|negative regulation of neuron apoptotic process;GO:0043576|regulation of respiratory gaseous exchange;GO:0045444|fat cell differentiation;GO:0045893|positive regulation of transcription, DNA-templated;GO:0045944|positive regulation of transcription by RNA polymerase II;GO:0051866|general adaptation syndrome;GO:0060041|retina development in camera-type eye;GO:0071376|cellular response to corticotropin-releasing hormone stimulus;GO:0071542|dopaminergic neuron differentiation;GO:2001234|negative regulation of apoptotic signaling pathway;","GO:0000785|chromatin;GO:0005634|nucleus;GO:0005667|transcription factor complex;GO:0005737|cytoplasm;GO:0016607|nuclear speck;","GO:0000977|RNA polymerase II regulatory region sequence-specific DNA binding;GO:0000978|RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0000981|DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228|DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677|DNA binding;GO:0004879|nuclear receptor activity;GO:0008270|zinc ion binding;GO:0035259|glucocorticoid receptor binding;GO:0043565|sequence-specific DNA binding;GO:0046982|protein heterodimerization activity;GO:1990837|sequence-specific double-stranded DNA binding;","K08558","NR4A2, NURR1; nuclear receptor subfamily 4 group A member 2"]
["ENSRNOG00000034139",399,15.5560575486229,33.5699721899283,113,4.34754987920045,9.38201263931458,3.57812054625208,1.83920199235084,{"v":2.04914356050085e-39,"d":"2.05E-39"},{"v":7.48683021679224e-38,"d":"7.49E-38"},"up","yes","Lyc2","protein_coding","chr7:52886883-52894446:+","gi|190360687|ref|NP_001121966.1|",492,{"v":6e-55,"d":"6.00E-55"},"putative lysozyme C-2 precursor [Rattus norvegicus]","gi|294584|gb|L12458.1|RATLYSZYM",907,0,"Rat lysozyme gene, complete cds","Q05820",191,{"v":1e-55,"d":"1.00E-55"},"Putative lysozyme C-2",".",".",".",".","pfam00062","Lys","C-type lysozyme/alpha-lactalbumin family. Alpha-lactalbumin is the regulatory subunit of lactose synthase, changing the substrate specificity of galactosyltransferase from N-acetylglucosamine to glucose. C-type lysozymes are secreted bacteriolytic enzymes that cleave the peptidoglycan of bacterial cell walls. Structure is a multi-domain, mixed alpha and beta fold, containing four conserved disulfide bonds.","GO:0019835|cytolysis;GO:0050829|defense response to Gram-negative bacterium;GO:0050830|defense response to Gram-positive bacterium;","GO:0005576|extracellular region;","GO:0003796|lysozyme activity;","K13915","LYZ; lysozyme C [EC:3.2.1.17]"]
["ENSRNOG00000061429",1290,54.4578507545928,108.534496553903,386,16.0804269757222,32.0482909626144,3.38659233593807,1.75983433158622,{"v":3.39737308667141e-116,"d":"3.40E-116"},{"v":3.87160325404627e-114,"d":"3.87E-114"},"up","yes","Rph3al","protein_coding","chr10:60690031-60801883:-","gi|19424292|ref|NP_598275.1|",1431,0,"rab effector Noc2 [Rattus norvegicus]","gi|61889106|ref|NM_133591.2|",1993,0,"Rattus norvegicus rabphilin 3A-like (without C2 domains) (Rph3al), mRNA","O54880",555,0,"Rab effector Noc2",".",".",".",".","pfam02318","FYVE_2","FYVE-type zinc finger. This FYVE-type zinc finger is found at the N-terminus of effector proteins including rabphilin-3A and regulating synaptic membrane exocytosis protein 2.","GO:0006886|intracellular protein transport;GO:0006887|exocytosis;GO:0009410|response to xenobiotic stimulus;GO:0017158|regulation of calcium ion-dependent exocytosis;GO:0032024|positive regulation of insulin secretion;GO:0042593|glucose homeostasis;GO:0045744|negative regulation of G protein-coupled receptor signaling pathway;GO:0050714|positive regulation of protein secretion;","GO:0005737|cytoplasm;GO:0030141|secretory granule;GO:0030658|transport vesicle membrane;GO:0030667|secretory granule membrane;","GO:0005515|protein binding;GO:0030274|LIM domain binding;GO:0031267|small GTPase binding;GO:0046872|metal ion binding;","K19939","RPH3AL; Rab effector Noc2"]
["ENSRNOG00000009629",337,10.4819170180588,28.3535855338492,102,3.13076501794476,8.4687193735406,3.34803696795483,1.74331545775405,{"v":2.74819941748687E-31,"d":"2.75E-31"},{"v":7.49493752288118e-30,"d":"7.49E-30"},"up","yes","Car2","protein_coding","chr2:86741626-86756818:-","gi|9506445|ref|NP_062164.1|",1191,{"v":4e-157,"d":"4.00E-157"},"carbonic anhydrase 2 [Rattus norvegicus]","gi|298916112|emb|FQ213417.1|",723,0,"Rattus norvegicus TL0AAA47YP08 mRNA sequence","P27139",463,{"v":1e-158,"d":"1.00E-158"},"Carbonic anhydrase 2","all2929",114,{"v":3e-27,"d":"3.00E-27"},"COG3338","pfam00194","Carb_anhydrase","Eukaryotic-type carbonic anhydrase.","GO:0001822|kidney development;GO:0002009|morphogenesis of an epithelium;GO:0006730|one-carbon metabolic process;GO:0009268|response to pH;GO:0010033|response to organic substance;GO:0010043|response to zinc ion;GO:0015670|carbon dioxide transport;GO:0030316|osteoclast differentiation;GO:0030641|regulation of cellular pH;GO:0032230|positive regulation of synaptic transmission, GABAergic;GO:0032849|positive regulation of cellular pH reduction;GO:0038166|angiotensin-activated signaling pathway;GO:0042475|odontogenesis of dentin-containing tooth;GO:0043627|response to estrogen;GO:0044070|regulation of anion transport;GO:0045124|regulation of bone resorption;GO:0045672|positive regulation of osteoclast differentiation;GO:0045780|positive regulation of bone resorption;GO:0046903|secretion;GO:0048545|response to steroid hormone;GO:0051453|regulation of intracellular pH;GO:0071498|cellular response to fluid shear stress;GO:2001150|positive regulation of dipeptide transmembrane transport;GO:2001225|regulation of chloride transport;","GO:0005615|extracellular space;GO:0005737|cytoplasm;GO:0005829|cytosol;GO:0005886|plasma membrane;GO:0005902|microvillus;GO:0016323|basolateral plasma membrane;GO:0030424|axon;GO:0043209|myelin sheath;GO:0045177|apical part of cell;","GO:0004064|arylesterase activity;GO:0004089|carbonate dehydratase activity;GO:0005515|protein binding;GO:0008270|zinc ion binding;GO:0016836|hydro-lyase activity;","K18245","CA2; carbonic anhydrase 2 [EC:4.2.1.1]"]
["ENSRNOG00000008015",780,41.299880141108,65.6255095442207,238,12.4357112680478,19.760345204928,3.3210710067886,1.73164856898535,{"v":1.79989841813581e-69,"d":"1.80E-69"},{"v":1.20486627403385e-67,"d":"1.20E-67"},"up","yes","Fos","protein_coding","chr6:105121170-105124036:+","gi|63147420|ref|NP_071533.1|",1595,0,"proto-oncogene c-Fos [Rattus norvegicus]","gi|148298807|ref|NM_022197.2|",1589,0,"Rattus norvegicus FBJ osteosarcoma oncogene (Fos), mRNA","P12841",619,0,"Proto-oncogene c-Fos",".",".",".",".","pfam07716","bZIP_2","Basic region leucine zipper.","GO:0001661|conditioned taste aversion;GO:0006355|regulation of transcription, DNA-templated;GO:0006357|regulation of transcription by RNA polymerase II;GO:0006366|transcription by RNA polymerase II;GO:0007179|transforming growth factor beta receptor signaling pathway;GO:0007399|nervous system development;GO:0007565|female pregnancy;GO:0007568|aging;GO:0009409|response to cold;GO:0009410|response to xenobiotic stimulus;GO:0009416|response to light stimulus;GO:0009612|response to mechanical stimulus;GO:0009629|response to gravity;GO:0009636|response to toxic substance;GO:0010468|regulation of gene expression;GO:0014070|response to organic cyclic compound;GO:0030431|sleep;GO:0031668|cellular response to extracellular stimulus;GO:0032496|response to lipopolysaccharide;GO:0032570|response to progesterone;GO:0032870|cellular response to hormone stimulus;GO:0034097|response to cytokine;GO:0034614|cellular response to reactive oxygen species;GO:0035902|response to immobilization stress;GO:0035914|skeletal muscle cell differentiation;GO:0035994|response to muscle stretch;GO:0045672|positive regulation of osteoclast differentiation;GO:0045893|positive regulation of transcription, DNA-templated;GO:0045944|positive regulation of transcription by RNA polymerase II;GO:0051412|response to corticosterone;GO:0051591|response to cAMP;GO:0060395|SMAD protein signal transduction;GO:0071276|cellular response to cadmium ion;GO:0071277|cellular response to calcium ion;GO:1901216|positive regulation of neuron death;GO:1902895|positive regulation of pri-miRNA transcription by RNA polymerase II;","GO:0005634|nucleus;GO:0005654|nucleoplasm;GO:0005667|transcription factor complex;GO:0005737|cytoplasm;GO:0005783|endoplasmic reticulum;GO:0005829|cytosol;GO:0016020|membrane;GO:0032993|protein-DNA complex;GO:0035976|transcription factor AP-1 complex;GO:0043005|neuron projection;","GO:0000976|transcription regulatory region sequence-specific DNA binding;GO:0000978|RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0000979|RNA polymerase II core promoter sequence-specific DNA binding;GO:0000981|DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228|DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677|DNA binding;GO:0003682|chromatin binding;GO:0003690|double-stranded DNA binding;GO:0003700|DNA-binding transcription factor activity;GO:0005515|protein binding;GO:0042802|identical protein binding;GO:0043565|sequence-specific DNA binding;GO:0044877|protein-containing complex binding;GO:0061629|RNA polymerase II sequence-specific DNA-binding transcription factor binding;GO:0070412|R-SMAD binding;GO:1990837|sequence-specific double-stranded DNA binding;","K04379","FOS; proto-oncogene protein c-fos"]
["ENSRNOG00000011200",500,20.4908106786256,42.0676343232184,153,6.1875689529035,12.7030790603108,3.31160926602851,1.72753246051312,{"v":4.90594498765859e-45,"d":"4.91E-45"},{"v":2.11541992062417e-43,"d":"2.12E-43"},"up","yes","Bhmt","protein_coding","chr2:24859873-24879742:-","gi|49259376|pdb|1UMY|A",2120,0,"Chain A, Bhmt From Rat Liver","gi|50926805|gb|BC078811.1|",1850,0,"Rattus norvegicus betaine-homocysteine methyltransferase, mRNA (cDNA clone MGC:93402 IMAGE:7130736), complete cds","O09171",816,0,"Betaine--homocysteine S-methyltransferase 1","BS_yitJ_1",96.3,{"v":7e-21,"d":"7.00E-21"},"COG0646","pfam02574","S-methyl_trans","Homocysteine S-methyltransferase. This is a family of related homocysteine S-methyltransferases enzymes: 5-methyltetrahydrofolate--homocysteine S-methyltransferases also known EC:2.1.1.13; Betaine--homocysteine S-methyltransferase (vitamin B12 dependent), EC:2.1.1.5,; and Homocysteine S-methyltransferase, EC:2.1.1.10,.","GO:0006479|protein methylation;GO:0006577|amino-acid betaine metabolic process;GO:0006579|amino-acid betaine catabolic process;GO:0009086|methionine biosynthetic process;GO:0010243|response to organonitrogen compound;GO:0032259|methylation;GO:0071267|L-methionine salvage;","GO:0005829|cytosol;GO:0032991|protein-containing complex;GO:0070062|extracellular exosome;","GO:0008168|methyltransferase activity;GO:0008270|zinc ion binding;GO:0044877|protein-containing complex binding;GO:0047150|betaine-homocysteine S-methyltransferase activity;","K00544","BHMT; betaine-homocysteine S-methyltransferase [EC:2.1.1.5]"]
["ENSRNOG00000020196",1362,247.499429581958,114.592235896446,422,75.674407649052,35.0372507415111,3.27058297872331,1.70954781784857,{"v":8.87610877566968e-118,"d":"8.88E-118"},{"v":1.03618106938865e-115,"d":"1.04E-115"},"up","yes","Scgb1a1","protein_coding","chr1:205977060-205980610:-","gi|6981694|ref|NP_037183.1|",420,{"v":3e-50,"d":"3.00E-50"},"uteroglobin precursor [Rattus norvegicus]","gi|6981693|ref|NM_013051.1|",454,0,"Rattus norvegicus secretoglobin family 1A member 1 (Scgb1a1), mRNA","P17559",166,{"v":1E-51,"d":"1.00E-51"},"Uteroglobin",".",".",".",".","pfam01099","Uteroglobin","Uteroglobin family. Uteroglobin is a homodimer of two identical 70 amino acid polypeptides linked by two disulphide bridges. The precise role of uteroglobin has still to be elucidated.","GO:0000122|negative regulation of transcription by RNA polymerase II;GO:0007165|signal transduction;GO:0009410|response to xenobiotic stimulus;GO:0010033|response to organic substance;GO:0010193|response to ozone;GO:0032496|response to lipopolysaccharide;GO:0032689|negative regulation of interferon-gamma production;GO:0032696|negative regulation of interleukin-13 production;GO:0032713|negative regulation of interleukin-4 production;GO:0032714|negative regulation of interleukin-5 production;GO:0034021|response to silicon dioxide;GO:0034097|response to cytokine;GO:0042130|negative regulation of T cell proliferation;GO:0043086|negative regulation of catalytic activity;GO:0043488|regulation of mRNA stability;GO:0050727|regulation of inflammatory response;GO:0051384|response to glucocorticoid;GO:0071774|response to fibroblast growth factor;","GO:0005615|extracellular space;GO:0005635|nuclear envelope;GO:0005737|cytoplasm;GO:0005783|endoplasmic reticulum;GO:0005791|rough endoplasmic reticulum;GO:0030141|secretory granule;","GO:0019834|phospholipase A2 inhibitor activity;GO:0097160|polychlorinated biphenyl binding;","K25464","SCGB1A, CC10; secretoglobin family 1A (uteroglobin)"]
["ENSRNOG00000019962",1388,59.6119208173835,116.779752881254,437,18.5210059465976,36.2826506493847,3.21861139666306,1.68643840162134,{"v":9.61420967349032e-118,"d":"9.61E-118"},{"v":1.10882341186218e-115,"d":"1.11E-115"},"up","yes","Sars2","protein_coding","chr1:84028986-84040725:+","gi|157819737|ref|NP_001099710.1|",2578,0,"serine--tRNA ligase, mitochondrial [Rattus norvegicus]","gi|157819736|ref|NM_001106240.1|",1859,0,"Rattus norvegicus seryl-tRNA synthetase 2, mitochondrial (Sars2), mRNA","Q9JJL8",966,0,"Serine--tRNA ligase, mitochondrial","BB0226",268,{"v":2e-81,"d":"2.00E-81"},"COG0172","pfam00587","tRNA-synt_2b","tRNA synthetase class II core domain (G, H, P, S and T). Other tRNA synthetase sub-families are too dissimilar to be included. This domain is the core catalytic domain of tRNA synthetases and includes glycyl, histidyl, prolyl, seryl and threonyl tRNA synthetases.","GO:0006434|seryl-tRNA aminoacylation;GO:0070158|mitochondrial seryl-tRNA aminoacylation;GO:0097056|selenocysteinyl-tRNA(Sec) biosynthetic process;","GO:0005739|mitochondrion;","GO:0000049|tRNA binding;GO:0004828|serine-tRNA ligase activity;GO:0005524|ATP binding;","K01875","SARS, serS; seryl-tRNA synthetase [EC:6.1.1.11]"]
["ENSRNOG00000068332",438,9.99491393196076,36.8512476671393,144,3.24270114336499,11.9558391155867,3.08228032435604,1.62399807670254,{"v":1.76030966402402e-36,"d":"1.76E-36"},{"v":5.63565988220941e-35,"d":"5.64E-35"},"up","yes","ENSRNOG00000068332","lncRNA","chr17:21500979-21504665:+",".",".",".",".","gi|672081473|ref|XM_006253805.2|",3687,0,"PREDICTED: Rattus norvegicus glucose-fructose oxidoreductase domain containing 1 (Gfod1), transcript variant X1, mRNA",".",".",".",".",".",".",".",".","pfam07223","DUF1421","Protein of unknown function (DUF1421). This family represents a conserved region approximately 350 residues long within a number of plant proteins of unknown function.",".",".",".",".","."]
["ENSRNOG00000003300",1241,43.9259017207522,104.411868390228,410,14.3209637422011,34.0409308152122,3.06724481057869,1.61694331916859,{"v":1.91910094511663e-99,"d":"1.92E-99"},{"v":1.83706578892063e-97,"d":"1.84E-97"},"up","yes","Btg2","protein_coding","chr13:45531925-45535628:-","gi|8393002|ref|NP_058955.1|",764,{"v":4e-93,"d":"4.00E-93"},"protein BTG2 precursor [Rattus norvegicus]","gi|8393001|ref|NM_017259.1|",2110,0,"Rattus norvegicus BTG family, member 2 (Btg2), mRNA","P27049",298,{"v":1e-94,"d":"1.00E-94"},"Protein BTG2",".",".",".",".","pfam07742","BTG","BTG family.","GO:0000122|negative regulation of transcription by RNA polymerase II;GO:0006479|protein methylation;GO:0006974|cellular response to DNA damage stimulus;GO:0008285|negative regulation of cell proliferation;GO:0008306|associative learning;GO:0009612|response to mechanical stimulus;GO:0009952|anterior/posterior pattern specification;GO:0010033|response to organic substance;GO:0010243|response to organonitrogen compound;GO:0014070|response to organic cyclic compound;GO:0017148|negative regulation of translation;GO:0021542|dentate gyrus development;GO:0021954|central nervous system neuron development;GO:0030182|neuron differentiation;GO:0031175|neuron projection development;GO:0035914|skeletal muscle cell differentiation;GO:0043066|negative regulation of apoptotic process;GO:0043434|response to peptide hormone;GO:0043524|negative regulation of neuron apoptotic process;GO:0045930|negative regulation of mitotic cell cycle;GO:0051602|response to electrical stimulus;GO:0060213|positive regulation of nuclear-transcribed mRNA poly(A) tail shortening;GO:2000178|negative regulation of neural precursor cell proliferation;","GO:0005575|cellular_component;GO:0005634|nucleus;GO:0005737|cytoplasm;","GO:0003714|transcription corepressor activity;GO:0005515|protein binding;","K14443","TOB; protein Tob/BTG"]
["ENSRNOG00000015279",994,31.5467585947032,83.6304570345582,339,10.6171399162368,28.1460379179437,2.97130478109822,1.57109659696963,{"v":7.64511039304244e-77,"d":"7.65E-77"},{"v":5.71742770004727E-75,"d":"5.72E-75"},"up","yes","Vtcn1","protein_coding","chr2:188253594-188321658:+","gi|66730411|ref|NP_001019415.1|",1294,{"v":4e-169,"d":"4.00E-169"},"V-set domain-containing T-cell activation inhibitor 1 precursor [Rattus norvegicus]","gi|66730410|ref|NM_001024244.1|",2619,0,"Rattus norvegicus V-set domain containing T cell activation inhibitor 1 (Vtcn1), mRNA","Q501W4",503,{"v":1e-170,"d":"1.00E-170"},"V-set domain-containing T-cell activation inhibitor 1",".",".",".",".","pfam07679","I-set","Immunoglobulin I-set domain.","GO:0001562|response to protozoan;GO:0001817|regulation of cytokine production;GO:0002250|adaptive immune response;GO:0032743|positive regulation of interleukin-2 production;GO:0042102|positive regulation of T cell proliferation;GO:0042130|negative regulation of T cell proliferation;GO:0043066|negative regulation of apoptotic process;GO:0050852|T cell receptor signaling pathway;GO:0050868|negative regulation of T cell activation;","GO:0009897|external side of plasma membrane;GO:0031225|anchored component of membrane;","GO:0005102|signaling receptor binding;","K06747","B7H4, VTCN1; immune costimulatory protein B7-H4"]
["ENSRNOG00000068679",2549,46.9382358896405,214.460799779767,882,16.0274709089447,73.2295145829687,2.92861151683293,1.55021683100836,{"v":2.74809313533214e-190,"d":"2.75E-190"},{"v":5.84582518129717e-188,"d":"5.85E-188"},"up","yes","Rpl30","lncRNA","chr7:65645991-65651363:-","gi|589934517|ref|XP_006980039.1|",329,{"v":1e-31,"d":"1.00E-31"},"PREDICTED: 60S ribosomal protein L30-like [Peromyscus maniculatus bairdii]","gi|435126|gb|K02928.1|MUSRPL30",469,0,"Mouse ribosomal protein L30 gene, complete cds","P62890",130,{"v":4e-33,"d":"4.00E-33"},"60S ribosomal protein L30","SPAC1250.05",88.2,{"v":8e-19,"d":"8.00E-19"},"COG1911","pfam01248","Ribosomal_L7Ae","Ribosomal protein L7Ae/L30e/S12e/Gadd45 family. This family includes: Ribosomal L7A from metazoa, Ribosomal L8-A and L8-B from fungi, 30S ribosomal protein HS6 from archaebacteria, 40S ribosomal protein S12 from eukaryotes, Ribosomal protein L30 from eukaryotes and archaebacteria. Gadd45 and MyD118.",".",".",".",".","."]
["ENSRNOG00000036603",417,10.2947203713509,35.0844070255641,148,3.60561788664505,12.2879457576863,2.85518895651196,1.5135862263594,{"v":1.38391682489137e-31,"d":"1.38E-31"},{"v":3.79587106729057e-30,"d":"3.80E-30"},"up","yes","Ifit1bl","protein_coding","chr1:232122562-232167518:-","gi|293344709|ref|XP_001079971.2|",2456,0,"PREDICTED: interferon-induced protein with tetratricopeptide repeats 1 isoform X2 [Rattus norvegicus]","gi|672014796|ref|XM_001079971.4|",2564,0,"PREDICTED: Rattus norvegicus interferon-induced protein with tetratricopeptide repeats 1-like B (Ifit1lb), transcript variant X2, mRNA","Q64282",550,0,"Interferon-induced protein with tetratricopeptide repeats 1",".",".",".",".","pfam13414","TPR_11","TPR repeat.","GO:0050688|regulation of defense response to virus;GO:0051607|defense response to virus;GO:0071357|cellular response to type I interferon;GO:0071360|cellular response to exogenous dsRNA;","GO:0005829|cytosol;","GO:0003723|RNA binding;","K14217","IFIT1; interferon-induced protein with tetratricopeptide repeats 1"]
["ENSRNOG00000013391",2184,17.6769049277362,183.751426723818,778,6.21402038368237,64.5947418883783,2.84468087265285,1.50826681447734,{"v":5.88676322359557E-157,"d":"5.89E-157"},{"v":9.5510572131661e-155,"d":"9.55E-155"},"up","yes","Sorbs2","protein_coding","chr16:46435237-46626514:-","gi|149021399|gb|EDL78862.1|",5682,0,"Arg/Abl-interacting protein ArgBP2, isoform CRA_c [Rattus norvegicus]","gi|16758605|ref|NM_053770.1|",5419,0,"Rattus norvegicus sorbin and SH3 domain containing 2 (Sorbs2), mRNA","O35413",2180,0,"Sorbin and SH3 domain-containing protein 2",".",".",".",".","pfam02208","Sorb","Sorbin homologous domain.","GO:0007015|actin filament organization;GO:0007219|Notch signaling pathway;GO:0061049|cell growth involved in cardiac muscle cell development;GO:0095500|acetylcholine receptor signaling pathway;GO:1904393|regulation of skeletal muscle acetylcholine-gated channel clustering;","GO:0005737|cytoplasm;GO:0005886|plasma membrane;GO:0005925|focal adhesion;GO:0014069|postsynaptic density;GO:0016020|membrane;GO:0016324|apical plasma membrane;GO:0030027|lamellipodium;GO:0030425|dendrite;GO:0043025|neuronal cell body;GO:0045202|synapse;GO:0048471|perinuclear region of cytoplasm;","GO:0019904|protein domain specific binding;GO:0042802|identical protein binding;","K23708","SORBS2; sorbin and SH3 domain-containing protein 2"]
["ENSRNOG00000010529",994,14.6002892867594,83.6304570345582,356,5.16017652703687,29.5574911468671,2.82941663143904,1.50050462913957,{"v":5.96291496989027e-72,"d":"5.96E-72"},{"v":4.16643815272411e-70,"d":"4.17E-70"},"up","yes","Thbs2","protein_coding","chr1:55670394-55699789:-","gi|281332082|ref|NP_001162609.1|",5716,0,"thrombospondin-2 precursor [Rattus norvegicus]","gi|281332081|ref|NM_001169138.1|",5728,0,"Rattus norvegicus thrombospondin 2 (Thbs2), mRNA","Q03350",2156,0,"Thrombospondin-2",".",".",".",".","pfam05735","TSP_C","Thrombospondin C-terminal region. This region is found at the C-terminus of thrombospondin and related proteins.","GO:0007155|cell adhesion;GO:0016525|negative regulation of angiogenesis;GO:0051965|positive regulation of synapse assembly;","GO:0005576|extracellular region;GO:0005604|basement membrane;GO:0031012|extracellular matrix;GO:0031091|platelet alpha granule;GO:0062023|collagen-containing extracellular matrix;","GO:0005509|calcium ion binding;GO:0008201|heparin binding;","K04659","THBS2S; thrombospondin 2/3/4/5"]
["ENSRNOG00000007882",798,22.1950229354897,67.1399443798566,290,7.95958067842091,24.0777315522232,2.78846635673438,1.47947186475109,{"v":5.85981801713459e-57,"d":"5.86E-57"},{"v":3.06520785076203e-55,"d":"3.07E-55"},"up","yes","Ablim2","protein_coding","chr14:74866281-74990334:-","gi|568934146|ref|XP_006503980.1|",3153,0,"PREDICTED: actin-binding LIM protein 2 isoform X12 [Mus musculus]","gi|568934145|ref|XM_006503917.1|",2311,0,"PREDICTED: Mus musculus actin-binding LIM protein 2 (Ablim2), transcript variant X12, mRNA","Q6KC51",1040,0,"Actin-binding LIM protein 2",".",".",".",".","pfam02209","VHP","Villin headpiece domain.","GO:0006351|transcription, DNA-templated;GO:0030032|lamellipodium assembly;GO:0030036|actin cytoskeleton organization;GO:0045944|positive regulation of transcription by RNA polymerase II;","GO:0005737|cytoplasm;GO:0015629|actin cytoskeleton;GO:0030016|myofibril;","GO:0003779|actin binding;GO:0046872|metal ion binding;GO:0051015|actin filament binding;","K07520","ABLIM; actin-binding LIM protein"]
["ENSRNOG00000023208",332,4.55675516975808,27.932909190617,122,1.65240662056097,10.1292525840387,2.75764761110138,1.46343811232772,{"v":2.54352556996354e-24,"d":"2.54E-24"},{"v":4.98934087385613e-23,"d":"4.99E-23"},"up","yes","Myorg","protein_coding","chr5:56648643-56664440:-","gi|157822809|ref|NP_001102441.1|",3603,0,"uncharacterized family 31 glucosidase KIAA1161 homolog [Rattus norvegicus]","gi|672052314|ref|XM_006238094.2|",4714,0,"PREDICTED: Rattus norvegicus similar to KIAA1161 protein (RGD1309821), transcript variant X2, mRNA","Q69ZQ1",1341,0,"Myogenesis-regulating glycosidase","TM0308",138,{"v":3E-32,"d":"3.00E-32"},"COG1501","pfam01055","Glyco_hydro_31","Glycosyl hydrolases family 31. Glycosyl hydrolases are key enzymes of carbohydrate metabolizm. Family 31 comprises of enzymes that are, or similar to, alpha- galactosidases.","GO:0005975|carbohydrate metabolic process;GO:0043568|positive regulation of insulin-like growth factor receptor signaling pathway;GO:0048741|skeletal muscle fiber development;GO:0051897|positive regulation of protein kinase B signaling;","GO:0005789|endoplasmic reticulum membrane;GO:0016021|integral component of membrane;GO:0031965|nuclear membrane;","GO:0004553|hydrolase activity, hydrolyzing O-glycosyl compounds;","K24727","MYORG; myogenesis-regulating glycosidase [EC:3.2.1.-]"]
["ENSRNOG00000058470",1267,7.38478596293976,106.599385375035,468,2.69182383967141,38.8564771256568,2.74341353773031,1.45597210810109,{"v":2.78735746426139E-87,"d":"2.79E-87"},{"v":2.32018021007135E-85,"d":"2.32E-85"},"up","yes","Col12a1","protein_coding","chr8:80547593-80665686:-","gi|672023106|ref|XP_008756047.1|",14897,0,"PREDICTED: collagen alpha-1(XII) chain isoform X1 [Rattus norvegicus]","gi|672023105|ref|XM_008757825.1|",12409,0,"PREDICTED: Rattus norvegicus collagen, type XII, alpha 1 (Col12a1), transcript variant X1, mRNA","Q60847",5464,0,"Collagen alpha-1(XII) chain",".",".",".",".","pfam00092","VWA","von Willebrand factor type A domain.","GO:0007155|cell adhesion;GO:0035987|endodermal cell differentiation;","GO:0005576|extracellular region;GO:0005581|collagen trimer;GO:0005595|collagen type XII trimer;GO:0005615|extracellular space;GO:0062023|collagen-containing extracellular matrix;","GO:0005201|extracellular matrix structural constituent;","K08132","COL12A; collagen type XII alpha"]
["ENSRNOG00000063373",733,20.5502005724219,61.6711519178382,272,7.52524214021157,22.5832516627749,2.73083579099876,1.44934256542715,{"v":6.21061307556696e-51,"d":"6.21E-51"},{"v":2.95777617319734e-49,"d":"2.96E-49"},"up","yes","Socs3","protein_coding","chr10:103193537-103197787:-","gi|672069906|ref|XP_008766620.1|",1113,{"v":2e-141,"d":"2.00E-141"},"PREDICTED: suppressor of cytokine signaling 3 isoform X1 [Rattus norvegicus]","gi|672069905|ref|XM_008768398.1|",2480,0,"PREDICTED: Rattus norvegicus suppressor of cytokine signaling 3 (Socs3), transcript variant X1, mRNA","O88583",428,{"v":4e-141,"d":"4.00E-141"},"Suppressor of cytokine signaling 3",".",".",".",".","pfam00017","SH2","SH2 domain.",".",".",".",".","."]
["ENSRNOG00000015354",4174,41.6881067580991,351.180611330227,1564,15.414731370009,129.853697060955,2.70443290625276,1.43532610639616,{"v":5.06486525809328e-277,"d":"5.06E-277"},{"v":1.73155685121577e-274,"d":"1.73E-274"},"up","yes","Aox1","protein_coding","chr9:59579649-59658770:+","gi|149046117|gb|EDL99010.1|",6822,0,"aldehyde oxidase 1 [Rattus norvegicus]","gi|281599344|gb|AC115467.4|",4219,0,"Rattus norvegicus BAC CH230-184L19 (Children's Hospital Oakland Research Institute Rat (BN/SsNHsd/MCW) BAC library) complete sequence","Q9Z0U5",2627,0,"Aldehyde oxidase 1","PA1523",497,{"v":2e-151,"d":"2.00E-151"},"COG4631","pfam02738","Ald_Xan_dh_C2","Molybdopterin-binding domain of aldehyde dehydrogenase.","GO:0006805|xenobiotic metabolic process;","GO:0005829|cytosol;","GO:0004031|aldehyde oxidase activity;GO:0005506|iron ion binding;GO:0016491|oxidoreductase activity;GO:0042802|identical protein binding;GO:0042803|protein homodimerization activity;GO:0043546|molybdopterin cofactor binding;GO:0050250|retinal oxidase activity;GO:0050660|flavin adenine dinucleotide binding;GO:0051287|NAD binding;GO:0051537|2 iron, 2 sulfur cluster binding;GO:0071949|FAD binding;GO:0102797|geranial:oxygen oxidoreductase activity;GO:0102798|heptaldehyde:oxygen oxidoreductase activity;","K00157","AOX; aldehyde oxidase [EC:1.2.3.1]"]
["ENSRNOG00000015075",408,14.1032003318595,34.3271896077462,153,5.21901358270784,12.7030790603108,2.70227316107927,1.43417351782253,{"v":1.10712846608561E-28,"d":"1.11E-28"},{"v":2.66282015484796e-27,"d":"2.66E-27"},"up","yes","Stc1","protein_coding","chr15:44299621-44310264:+","gi|803011834|ref|XP_004004231.2|",1291,{"v":4e-168,"d":"4.00E-168"},"PREDICTED: stanniocalcin-1 [Ovis aries]","gi|51036665|ref|NM_031123.2|",2434,0,"Rattus norvegicus stanniocalcin 1 (Stc1), mRNA","P97574",485,{"v":4E-165,"d":"4.00E-165"},"Stanniocalcin-1",".",".",".",".","pfam03298","Stanniocalcin","Stanniocalcin family.","GO:0001503|ossification;GO:0001886|endothelial cell morphogenesis;GO:0003421|growth plate cartilage axis specification;GO:0006874|cellular calcium ion homeostasis;GO:0007165|signal transduction;GO:0007566|embryo implantation;GO:0010596|negative regulation of endothelial cell migration;GO:0014070|response to organic cyclic compound;GO:0030336|negative regulation of cell migration;GO:0033280|response to vitamin D;GO:0035988|chondrocyte proliferation;GO:0044070|regulation of anion transport;GO:0046697|decidualization;GO:0051926|negative regulation of calcium ion transport;GO:0060348|bone development;GO:0071320|cellular response to cAMP;GO:0071385|cellular response to glucocorticoid stimulus;GO:0071456|cellular response to hypoxia;GO:0086004|regulation of cardiac muscle cell contraction;GO:0090280|positive regulation of calcium ion import;GO:1903403|negative regulation of renal phosphate excretion;","GO:0005615|extracellular space;GO:0005634|nucleus;GO:0005737|cytoplasm;GO:0016324|apical plasma membrane;","GO:0003674|molecular_function;GO:0005179|hormone activity;GO:0042802|identical protein binding;",".","."]
["ENSRNOG00000019416",1328,41.3055958456444,111.731636762468,499,15.3161935681807,41.430303601929,2.69685778400296,1.43127944455335,{"v":3.98870736085392e-89,"d":"3.99E-89"},{"v":3.47109403839539E-87,"d":"3.47E-87"},"up","yes","ENSRNOG00000019416","protein_coding","chr1:79850014-79871249:-","gi|672035156|ref|XP_008757184.1|",3130,0,"PREDICTED: zinc finger protein 61 isoform X1 [Rattus norvegicus]","gi|672035155|ref|XM_008758962.1|",2406,0,"PREDICTED: Rattus norvegicus zinc finger protein 61 (Zfp61), transcript variant X1, mRNA","Q9NYT6",573,0,"Zinc finger protein 226",".",".",".",".","pfam01352","KRAB","KRAB box. The KRAB domain (or Kruppel-associated box) is present in about a third of zinc finger proteins containing C2H2 fingers. The KRAB domain is found to be involved in protein-protein interactions. The KRAB domain is generally encoded by two exons. The regions coded by the two exons are known as KRAB-A and KRAB-B. The A box plays an important role in repression by binding to corepressors, while the B box is thought to enhance this repression brought about by the A box. KRAB-containing proteins are thought to have critical functions in cell proliferation and differentiation, apoptosis and neoplastic transformation.","GO:0000122|negative regulation of transcription by RNA polymerase II;GO:0006357|regulation of transcription by RNA polymerase II;",".","GO:0000977|RNA polymerase II regulatory region sequence-specific DNA binding;GO:0000981|DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001227|DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0046872|metal ion binding;","K09228","KRAB; KRAB domain-containing zinc finger protein"]
["ENSRNOG00000016538",1284,17.9064619496146,108.029684942024,488,6.71589761912067,40.517010336155,2.66627976856489,1.4148281681031,{"v":8.85343406460134e-85,"d":"8.85E-85"},{"v":7.06248277174184e-83,"d":"7.06E-83"},"up","yes","Itga8","protein_coding","chr17:75304008-75501510:-","gi|291190715|ref|NP_001167443.1|",5446,0,"integrin alpha-8 [Rattus norvegicus]","gi|291190714|ref|NM_001173972.1|",4312,0,"Rattus norvegicus integrin subunit alpha 8 (Itga8), mRNA","A2ARA8",2022,0,"Integrin alpha-8",".",".",".",".","pfam08441","Integrin_alpha2","Integrin alpha. This domain is found in integrin alpha and integrin alpha precursors to the C terminus of a number of pfam01839 repeats and to the N-terminus of the pfam00357 cytoplasmic region. This region is composed of three immunoglobulin-like domains.","GO:0001656|metanephros development;GO:0001822|kidney development;GO:0007160|cell-matrix adhesion;GO:0007229|integrin-mediated signaling pathway;GO:0007420|brain development;GO:0007613|memory;GO:0030030|cell projection organization;GO:0030198|extracellular matrix organization;GO:0030511|positive regulation of transforming growth factor beta receptor signaling pathway;GO:0034446|substrate adhesion-dependent cell spreading;GO:0042472|inner ear morphogenesis;GO:0045184|establishment of protein localization;GO:0048333|mesodermal cell differentiation;GO:0048745|smooth muscle tissue development;GO:2000721|positive regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation;","GO:0005783|endoplasmic reticulum;GO:0005886|plasma membrane;GO:0008305|integrin complex;GO:0009986|cell surface;GO:0014069|postsynaptic density;GO:0032591|dendritic spine membrane;GO:0043204|perikaryon;GO:0045177|apical part of cell;","GO:0003674|molecular_function;","K06584","ITGA8; integrin alpha 8"]
["ENSRNOG00000033517",2602,258.465134613965,218.919969018028,1004,98.4164901617561,83.3587671670074,2.62623808458476,1.39299771131071,{"v":6.7938506956365e-166,"d":"6.79E-166"},{"v":1.1409537311882E-163,"d":"1.14E-163"},"up","yes","ENSRNOG00000033517","protein_coding","chr1:19107386-19108232:+","gi|820987686|ref|XP_012362357.1|",928,{"v":2e-123,"d":"2.00E-123"},"PREDICTED: translationally-controlled tumor protein isoform X2 [Nomascus leucogenys]","gi|298914786|emb|FQ232768.1|",783,0,"Rattus norvegicus TL0AEA64YI02 mRNA sequence","P63029",349,{"v":1e-120,"d":"1.00E-120"},"Translationally-controlled tumor protein",".",".",".",".","pfam00838","TCTP","Translationally controlled tumor protein.",".",".",".",".","."]
["ENSRNOG00000042309",564,11.4287792670015,47.4522915165903,218,4.359299613302,18.0998119944299,2.6217007961847,1.39050304616555,{"v":2.66373630236224E-37,"d":"2.66E-37"},{"v":8.8230812162539e-36,"d":"8.82E-36"},"up","yes","Kiaa0408L","protein_coding","chr1:28615606-28630309:-","gi|242117994|ref|NP_001138331.2|",3217,0,"uncharacterized protein KIAA0408 homolog [Rattus norvegicus]","gi|242117993|ref|NM_001144859.2|",4152,0,"Rattus norvegicus SOGA family member 3 (Soga3), mRNA",".",".",".",".",".",".",".",".","pfam14818","DUF4482","Domain of unknown function (DUF4482). This family is found in eukaryotes, and is approximately 140 amino acids in length. The family is found in association with pfam11365.",".",".",".",".","."]
["ENSRNOG00000055934",2888,131.984060755518,242.982655850909,1130,50.9615026578739,93.8201263931458,2.58987772871579,1.3728839881283,{"v":6.2926399196781e-180,"d":"6.29E-180"},{"v":1.2047301157193E-177,"d":"1.20E-177"},"up","yes","Dmkn","protein_coding","chr1:86014188-86030006:+","gi|290563809|ref|NP_001166828.1|",1739,0,"dermokine precursor [Rattus norvegicus]","gi|290563808|ref|NM_001173357.1|",1667,0,"Rattus norvegicus dermokine (Dmkn), mRNA","Q6P253",313,{"v":1E-97,"d":"1.00E-97"},"Dermokine",".",".",".",".","pfam04625","DEC-1_N","DEC-1 protein, N-terminal region. The defective chorion-1 gene (dec-1) in Drosophila encodes follicle cell proteins necessary for proper eggshell assembly. Multiple products of the dec-1 gene are formed by alternative RNA splicing and proteolytic processing. Cleavage products include S80 (80 kDa) which is incorporated into the eggshell, and further proteolysis of S80 gives S60 (60 kDa).","GO:1903575|cornified envelope assembly;","GO:0005615|extracellular space;",".",".","."]
["ENSRNOG00000020525",488,6.68044437023449,41.0580110994611,191,2.58022976899729,15.8580921602573,2.58908894490841,1.37244452807082,{"v":6.75005057126192e-32,"d":"6.75E-32"},{"v":1.87834548035936E-30,"d":"1.88E-30"},"up","yes","Col5a3","protein_coding","chr8:19304571-19349853:-","gi|672061032|ref|XP_008764201.1|",1927,0,"PREDICTED: collagen alpha-3(V) chain isoform X1 [Rattus norvegicus]","gi|672061031|ref|XM_008765979.1|",6117,0,"PREDICTED: Rattus norvegicus collagen, type V, alpha 3 (Col5a3), transcript variant X1, mRNA","P25940",499,{"v":1e-144,"d":"1.00E-144"},"Collagen alpha-3(V) chain",".",".",".",".","pfam01410","COLFI","Fibrillar collagen C-terminal domain. Found at C-termini of fibrillar collagens: Ephydatia muelleri procollagen EMF1 alpha, vertebrate collagens alpha(1)III, alpha(1)II, alpha(2)V etc.","GO:0007160|cell-matrix adhesion;GO:0030198|extracellular matrix organization;","GO:0005588|collagen type V trimer;GO:0005615|extracellular space;GO:0031012|extracellular matrix;GO:0062023|collagen-containing extracellular matrix;","GO:0005201|extracellular matrix structural constituent;GO:0008201|heparin binding;GO:0043394|proteoglycan binding;","K19721","COL5AS; collagen type V/XI/XXIV/XXVII, alpha"]
["ENSRNOG00000031890",320,3.10964263881494,26.9232859668597,128,1.22746737666761,10.6274125471882,2.53338108851181,1.34106411343104,{"v":8.68161438853042e-21,"d":"8.68E-21"},{"v":1.38971644938903E-19,"d":"1.39E-19"},"up","yes","Ncam1","protein_coding","chr8:49865633-50166014:-","gi|564363529|ref|XP_006243050.1|",4997,0,"PREDICTED: neural cell adhesion molecule 1 isoform X5 [Rattus norvegicus]","gi|672061763|ref|XM_006242988.2|",3673,0,"PREDICTED: Rattus norvegicus neural cell adhesion molecule 1 (Ncam1), transcript variant X5, mRNA","P13595",1911,0,"Neural cell adhesion molecule 1",".",".",".",".","pfam07679","I-set","Immunoglobulin I-set domain.","GO:0001928|regulation of exocyst assembly;GO:0007155|cell adhesion;GO:0007166|cell surface receptor signaling pathway;GO:0007413|axonal fasciculation;GO:0007420|brain development;GO:0007568|aging;GO:0007611|learning or memory;GO:0009410|response to xenobiotic stimulus;GO:0010035|response to inorganic substance;GO:0010288|response to lead ion;GO:0014012|peripheral nervous system axon regeneration;GO:0014823|response to activity;GO:0016338|calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules;GO:0021794|thalamus development;GO:0031100|animal organ regeneration;GO:0031175|neuron projection development;GO:0033555|multicellular organismal response to stress;GO:0034109|homotypic cell-cell adhesion;GO:0042220|response to cocaine;GO:0048666|neuron development;GO:0050804|modulation of chemical synaptic transmission;GO:0050850|positive regulation of calcium-mediated signaling;GO:0051930|regulation of sensory perception of pain;GO:0060045|positive regulation of cardiac muscle cell proliferation;GO:0060548|negative regulation of cell death;GO:0071219|cellular response to molecule of bacterial origin;GO:0071241|cellular response to inorganic substance;GO:0071679|commissural neuron axon guidance;GO:2001260|regulation of semaphorin-plexin signaling pathway;","GO:0005829|cytosol;GO:0005886|plasma membrane;GO:0005911|cell-cell junction;GO:0009897|external side of plasma membrane;GO:0009986|cell surface;GO:0016021|integral component of membrane;GO:0030424|axon;GO:0030426|growth cone;GO:0043005|neuron projection;GO:0043025|neuronal cell body;GO:0098685|Schaffer collateral - CA1 synapse;GO:0098978|glutamatergic synapse;GO:0099055|integral component of postsynaptic membrane;GO:0099056|integral component of presynaptic membrane;","GO:0005104|fibroblast growth factor receptor binding;GO:0005515|protein binding;GO:0008092|cytoskeletal protein binding;GO:0008201|heparin binding;GO:0019902|phosphatase binding;GO:0030275|LRR domain binding;","K06491","NCAM, CD56; neural cell adhesion molecule"]
["ENSRNOG00000047307",392,20.4851088878281,32.9810253094032,157,8.09638863503759,13.0351857024105,2.53015385145638,1.33922511376726,{"v":4.70434903748364e-25,"d":"4.70E-25"},{"v":9.56104846541854e-24,"d":"9.56E-24"},"up","yes","Cntfr","protein_coding","chr5:56823965-56841392:-","gi|149045684|gb|EDL98684.1|",1676,0,"ciliary neurotrophic factor receptor, isoform CRA_b [Rattus norvegicus]","gi|51556266|ref|NM_001003929.1|",1242,0,"Rattus norvegicus ciliary neurotrophic factor receptor (Cntfr), mRNA","Q08406",648,0,"Ciliary neurotrophic factor receptor subunit alpha",".",".",".",".","pfam00041","fn3","Fibronectin type III domain.","GO:0001967|suckling behavior;GO:0003360|brainstem development;GO:0007548|sex differentiation;GO:0008284|positive regulation of cell proliferation;GO:0019221|cytokine-mediated signaling pathway;GO:0043524|negative regulation of neuron apoptotic process;GO:0060538|skeletal muscle organ development;GO:0070120|ciliary neurotrophic factor-mediated signaling pathway;","GO:0009897|external side of plasma membrane;GO:0016324|apical plasma membrane;GO:0031225|anchored component of membrane;GO:0043235|receptor complex;GO:0070110|ciliary neurotrophic factor receptor complex;GO:0097059|CNTFR-CLCF1 complex;","GO:0004896|cytokine receptor activity;GO:0004897|ciliary neurotrophic factor receptor activity;GO:0005102|signaling receptor binding;GO:0019955|cytokine binding;","K05059","CNTFR; ciliary neurotrophic factor receptor"]
["ENSRNOG00000034038",687,7.09039862120977,57.8009295601021,276,2.81101058695713,22.9153583048745,2.52236638812698,1.33477785058361,{"v":1.96217464230944e-42,"d":"1.96E-42"},{"v":7.85898840757892e-41,"d":"7.86E-41"},"up","yes","AABR07005844.1","protein_coding","chr1:185617480-185900277:+","gi|672014845|ref|XP_006223754.2|",3764,0,"PREDICTED: LOW QUALITY PROTEIN: deleted in malignant brain tumors 1 protein-like isoform X6, partial [Rattus norvegicus]","gi|43429891|gb|AY548057.1|",2273,0,"Rattus norvegicus pancrin mRNA, complete cds","Q9UGM3",1397,0,"Deleted in malignant brain tumors 1 protein",".",".",".",".","pfam00530","SRCR","Scavenger receptor cysteine-rich domain. These domains are disulphide rich extracellular domains. These domains are found in several extracellular receptors and may be involved in protein-protein interactions.",".",".",".",".","."]
["ENSRNOG00000061910",496,17.2728034969506,41.7310932486326,200,6.87306792424733,16.6053321049815,2.51311403980372,1.32947613915583,{"v":6.23039558761179e-31,"d":"6.23E-31"},{"v":1.66594049828187e-29,"d":"1.67E-29"},"up","yes","Igfbp3","protein_coding","chr14:82056347-82064083:-","gi|124064|sp|P15473.2|IBP3_RAT",1160,{"v":1e-149,"d":"1.00E-149"},"RecName: Full=Insulin-like growth factor-binding protein 3; Short=IBP-3; Short=IGF-binding protein 3; Short=IGFBP-3; Flags: Precursor","gi|298231181|ref|NM_012588.2|",2416,0,"Rattus norvegicus insulin-like growth factor binding protein 3 (Igfbp3), mRNA","P15473",451,{"v":3e-151,"d":"3.00E-151"},"Insulin-like growth factor-binding protein 3",".",".",".",".","pfam00086","Thyroglobulin_1","Thyroglobulin type-1 repeat. Thyroglobulin type 1 repeats are thought to be involved in the control of proteolytic degradation. The domain usually contains six conserved cysteines. These form three disulphide bridges. Cysteines 1 pairs with 2, 3 with 4 and 5 with 6.","GO:0001558|regulation of cell growth;GO:0001649|osteoblast differentiation;GO:0001666|response to hypoxia;GO:0001933|negative regulation of protein phosphorylation;GO:0006468|protein phosphorylation;GO:0007565|female pregnancy;GO:0007568|aging;GO:0008285|negative regulation of cell proliferation;GO:0009410|response to xenobiotic stimulus;GO:0010666|positive regulation of cardiac muscle cell apoptotic process;GO:0010906|regulation of glucose metabolic process;GO:0014912|negative regulation of smooth muscle cell migration;GO:0032496|response to lipopolysaccharide;GO:0032868|response to insulin;GO:0040008|regulation of growth;GO:0043065|positive regulation of apoptotic process;GO:0043410|positive regulation of MAPK cascade;GO:0043567|regulation of insulin-like growth factor receptor signaling pathway;GO:0043568|positive regulation of insulin-like growth factor receptor signaling pathway;GO:0044342|type B pancreatic cell proliferation;GO:0045663|positive regulation of myoblast differentiation;GO:0048662|negative regulation of smooth muscle cell proliferation;GO:0050790|regulation of catalytic activity;GO:0060416|response to growth hormone;GO:0061771|response to caloric restriction;GO:0071392|cellular response to estradiol stimulus;GO:1902512|positive regulation of apoptotic DNA fragmentation;GO:1904017|cellular response to Thyroglobulin triiodothyronine;GO:1990418|response to insulin-like growth factor stimulus;GO:2000844|negative regulation of testosterone secretion;","GO:0000792|heterochromatin;GO:0005615|extracellular space;GO:0005634|nucleus;GO:0031091|platelet alpha granule;GO:0042567|insulin-like growth factor ternary complex;GO:0042568|insulin-like growth factor binary complex;","GO:0001968|fibronectin binding;GO:0005515|protein binding;GO:0005520|insulin-like growth factor binding;GO:0008160|protein tyrosine phosphatase activator activity;GO:0031994|insulin-like growth factor I binding;GO:0031995|insulin-like growth factor II binding;","K10138","IGFBP3; insulin-like growth factor-binding protein 3"]
["ENSRNOG00000050848",475,9.82888652411645,39.9642526070575,192,3.92058997067936,15.9411188207823,2.50699170217315,1.32595722104084,{"v":1.40445883642025e-29,"d":"1.40E-29"},{"v":3.48296091094415e-28,"d":"3.48E-28"},"up","yes","Dtx1","protein_coding","chr12:35849617-35880838:+","gi|60360548|dbj|BAD90518.1|",2979,0,"mKIAA4160 protein [Mus musculus]","gi|672073190|ref|XM_006249412.2|",3596,0,"PREDICTED: Rattus norvegicus deltex 1, E3 ubiquitin ligase (Dtx1), transcript variant X1, mRNA","Q61010",1058,0,"E3 ubiquitin-protein ligase DTX1",".",".",".",".","pfam02825","WWE","WWE domain. The WWE domain is named after three of its conserved residues and is predicted to mediate specific protein- protein interactions in ubiquitin and ADP ribose conjugation systems.","GO:0007219|Notch signaling pathway;GO:0008593|regulation of Notch signaling pathway;GO:0010001|glial cell differentiation;GO:0016567|protein ubiquitination;GO:0045581|negative regulation of T cell differentiation;GO:0045665|negative regulation of neuron differentiation;GO:1990830|cellular response to leukemia inhibitory factor;","GO:0005654|nucleoplasm;GO:0005829|cytosol;GO:0016604|nuclear body;","GO:0005112|Notch binding;GO:0008270|zinc ion binding;GO:0031625|ubiquitin protein ligase binding;GO:0061630|ubiquitin protein ligase activity;","K06058","DTX; deltex [EC:2.3.2.27]"]
["ENSRNOG00000007607",3414,107.821999684285,287.237807158935,1401,43.6637955688422,116.320351395395,2.46936846143592,1.3041421211406,{"v":2.2540765930002e-196,"d":"2.25E-196"},{"v":4.90391442402945E-194,"d":"4.90E-194"},"up","yes","Nr4a1","protein_coding","chr7:132374840-132389297:+","gi|399498497|ref|NP_077364.2|",2573,0,"nuclear receptor subfamily 4 group A member 1 [Rattus norvegicus]","gi|399498496|ref|NM_024388.2|",2488,0,"Rattus norvegicus nuclear receptor subfamily 4, group A, member 1 (Nr4a1), mRNA","P22829",995,0,"Nuclear receptor subfamily 4 group A member 1",".",".",".",".","pfam00105","zf-C4","Zinc finger, C4 type (two domains). In nearly all cases, this is the DNA binding domain of a nuclear hormone receptor. The alignment contains two Zinc finger domains that are too dissimilar to be aligned with each other.","GO:0001938|positive regulation of endothelial cell proliferation;GO:0001975|response to amphetamine;GO:0002042|cell migration involved in sprouting angiogenesis;GO:0006355|regulation of transcription, DNA-templated;GO:0006357|regulation of transcription by RNA polymerase II;GO:0006915|apoptotic process;GO:0014860|neurotransmitter secretion involved in regulation of skeletal muscle contraction;GO:0030522|intracellular receptor signaling pathway;GO:0032496|response to lipopolysaccharide;GO:0035767|endothelial cell chemotaxis;GO:0035914|skeletal muscle cell differentiation;GO:0035924|cellular response to vascular endothelial growth factor stimulus;GO:0043065|positive regulation of apoptotic process;GO:0043154|negative regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0044344|cellular response to fibroblast growth factor stimulus;GO:0045444|fat cell differentiation;GO:0045786|negative regulation of cell cycle;GO:0045893|positive regulation of transcription, DNA-templated;GO:0045944|positive regulation of transcription by RNA polymerase II;GO:0051602|response to electrical stimulus;GO:0061469|regulation of type B pancreatic cell proliferation;GO:0071310|cellular response to organic substance;GO:0071376|cellular response to corticotropin-releasing hormone stimulus;","GO:0005634|nucleus;GO:0005654|nucleoplasm;GO:0005667|transcription factor complex;GO:0005737|cytoplasm;GO:0005739|mitochondrion;GO:0005829|cytosol;GO:0031965|nuclear membrane;GO:0098793|presynapse;","GO:0000978|RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0000981|DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228|DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677|DNA binding;GO:0004879|nuclear receptor activity;GO:0005515|protein binding;GO:0008270|zinc ion binding;GO:0035259|glucocorticoid receptor binding;GO:0042802|identical protein binding;GO:0043565|sequence-specific DNA binding;GO:0046982|protein heterodimerization activity;GO:1990837|sequence-specific double-stranded DNA binding;","K04465","NR4A1, HMR; nuclear receptor subfamily 4 group A member 1"]
["ENSRNOG00000065998",287,16.3929545835216,24.1468221015273,118,6.65115135230083,9.79714594193912,2.46467922848437,1.30139989585753,{"v":5.01313325515425e-18,"d":"5.01E-18"},{"v":6.64659079061187e-17,"d":"6.65E-17"},"up","yes","ENSRNOG00000065998","lncRNA","chrX:32891490-32892962:+",".",".",".",".","gi|672087360|ref|XM_008773173.1|",1473,0,"PREDICTED: Rattus norvegicus Nance-Horan syndrome (congenital cataracts and dental anomalies) (Nhs), transcript variant X1, mRNA",".",".",".",".",".",".",".",".","pfam13809","Tubulin_2","Tubulin like. Many of the residues conserved in Tubulin, pfam00091, are also highly conserved in this family.",".",".",".",".","."]
["ENSRNOG00000067172",1205,70.3560018868538,101.382998718956,509,29.3272520521707,42.260570207178,2.39899741584026,1.26243160358531,{"v":3.52366077403991e-67,"d":"3.52E-67"},{"v":2.27907840803679E-65,"d":"2.28E-65"},"up","yes","ENSRNOG00000067172","lncRNA","chr1:214623344-214624784:-","gi|149062551|gb|EDM12974.1|",176,{"v":5e-13,"d":"5.00E-13"},"rCG48576 [Rattus norvegicus]","gi|672039938|ref|XM_006231152.2|",1441,0,"PREDICTED: Rattus norvegicus prune homolog 2 (Drosophila) (Prune2), transcript variant X2, mRNA",".",".",".",".",".",".",".",".","pfam10321","7TM_GPCR_Srt","Serpentine type 7TM GPCR chemoreceptor Srt. Chemoreception is mediated in Caenorhabditis elegans by members of the seven-transmembrane G-protein-coupled receptor class (7TM GPCRs) of proteins which are of the serpentine type. Srt is a member of the Srg superfamily of chemoreceptors. Chemoperception is one of the central senses of soil nematodes like C. elegans which are otherwise 'blind' and 'deaf'.",".",".",".",".","."]
["ENSRNOG00000047098",452,10.67035393608,38.0291414281894,192,4.47281672861456,15.9411188207823,2.38560052501529,1.25435248023771,{"v":4.953059270487e-26,"d":"4.95E-26"},{"v":1.05129324354111E-24,"d":"1.05E-24"},"up","yes","Hbb-b1","protein_coding","chr1:158120200-158252012:-","gi|40445397|ref|NP_942071.1|",744,{"v":1e-96,"d":"1.00E-96"},"hemoglobin, beta adult major chain [Rattus norvegicus]","gi|298901836|emb|FQ228130.1|",564,0,"Rattus norvegicus TL0AEA10YG08 mRNA sequence","P11517",284,{"v":2E-95,"d":"2.00E-95"},"Hemoglobin subunit beta-2",".",".",".",".","pfam00042","Globin","Globin.","GO:0015671|oxygen transport;GO:0098869|cellular oxidant detoxification;","GO:0005833|hemoglobin complex;","GO:0005344|oxygen carrier activity;GO:0019825|oxygen binding;GO:0020037|heme binding;GO:0046872|metal ion binding;","K13823","HBB; hemoglobin subunit beta"]
["ENSRNOG00000003546",1209,95.4217071233978,101.719539793542,515,40.1113791466487,42.7587301703275,2.37891862991129,1.25030592572223,{"v":2.05340332607236e-66,"d":"2.05E-66"},{"v":1.31041812774613E-64,"d":"1.31E-64"},"up","yes","Tnfrsf12a","protein_coding","chr10:12689890-12709045:-","gi|524963570|ref|XP_005081703.1|",379,{"v":1e-44,"d":"1.00E-44"},"PREDICTED: tumor necrosis factor receptor superfamily member 12A [Mesocricetus auratus]","gi|298914578|emb|FQ229590.1|",847,0,"Rattus norvegicus TL0ADA47YG14 mRNA sequence","Q9NP84",146,{"v":5e-41,"d":"5.00E-41"},"Tumor necrosis factor receptor superfamily member 12A",".",".",".",".","pfam12191","stn_TNFRSF12A","tumor necrosis factor receptor stn_TNFRSF12A_TNFR domain. This family of proteins is found in eukaryotes. Proteins in this family are typically between 129 and 184 amino acids in length. This is the stn_TNFRSF12A_TNFR domain from the tumor necrosis factor receptor. The function of this domain is unknown.","GO:0006931|substrate-dependent cell migration, cell attachment to substrate;GO:0007155|cell adhesion;GO:0043065|positive regulation of apoptotic process;GO:0045765|regulation of angiogenesis;GO:0045773|positive regulation of axon extension;GO:0061041|regulation of wound healing;GO:0097191|extrinsic apoptotic signaling pathway;GO:2001238|positive regulation of extrinsic apoptotic signaling pathway;","GO:0001726|ruffle;GO:0005886|plasma membrane;GO:0009986|cell surface;GO:0016021|integral component of membrane;",".","K05149","TNFRSF12A, FN14, TWEAKR, CD266; tumor necrosis factor receptor superfamily member 12A"]
["ENSRNOG00000018602",1943,19.0752423547289,163.474826980026,832,8.06046459238311,69.0781815567233,2.36651896873964,1.24276648598794,{"v":1.30336009151271e-104,"d":"1.30E-104"},{"v":1.35613673959016e-102,"d":"1.36E-102"},"up","yes","Camta1","protein_coding","chr5:161510283-162356723:-","gi|307133744|ref|NP_001182488.1|",8450,0,"calmodulin-binding transcription activator 1 isoform 1 [Rattus norvegicus]","gi|307133743|ref|NM_001195559.1|",8460,0,"Rattus norvegicus calmodulin binding transcription activator 1 (Camta1), transcript variant 1, mRNA","A2A891",3160,0,"Calmodulin-binding transcription activator 1",".",".",".",".","pfam03859","CG-1","CG-1 domain. CG-1 domains are highly conserved domains of about 130 amino-acid residues containing a predicted bipartite NLS and named after a partial cDNA clone isolated from parsley encoding a sequence-specific DNA-binding protein. CG-1 domains are associated with CAMTA proteins (for CAlModulin -binding Transcription Activator) that are transcription factors containing a calmodulin -binding domain and ankyrins (ANK) motifs.","GO:0035307|positive regulation of protein dephosphorylation;GO:0045944|positive regulation of transcription by RNA polymerase II;GO:0050885|neuromuscular process controlling balance;GO:0070886|positive regulation of calcineurin-NFAT signaling cascade;","GO:0005730|nucleolus;GO:0005829|cytosol;","GO:0043565|sequence-specific DNA binding;","K21596","CAMTA; calmodulin-binding transcription activator"]
["ENSRNOG00000019441",1212,66.561322192873,101.971945599481,523,28.34395786849,43.4229434545267,2.34834254629164,1.23164286576969,{"v":4.59862870533004e-65,"d":"4.60E-65"},{"v":2.84003399108688e-63,"d":"2.84E-63"},"up","yes","Hsd3b2","protein_coding","chr2:186095897-186101852:-","gi|388201|gb|AAA40606.1|",1862,0,"3 hydroxysteroid dehydrogenase [Rattus norvegicus]","gi|61889128|ref|NM_017265.4|",1512,0,"Rattus norvegicus hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 6 (Hsd3b6), mRNA","Q62878",725,0,"3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 4","YGL001c",104,{"v":8e-24,"d":"8.00E-24"},"COG0451","pfam01073","3Beta_HSD","3-beta hydroxysteroid dehydrogenase/isomerase family. The enzyme 3 beta-hydroxysteroid dehydrogenase/5-ene-4-ene isomerase (3 beta-HSD) catalyses the oxidation and isomerization of 5-ene-3 beta-hydroxypregnene and 5-ene-hydroxyandrostene steroid precursors into the corresponding 4-ene-ketosteroids necessary for the formation of all classes of steroid hormones.","GO:0006694|steroid biosynthetic process;GO:0006700|C21-steroid hormone biosynthetic process;GO:0006702|androgen biosynthetic process;GO:0008207|C21-steroid hormone metabolic process;GO:0010288|response to lead ion;GO:0021766|hippocampus development;GO:0033327|Leydig cell differentiation;GO:0034698|response to gonadotropin;GO:0034757|negative regulation of iron ion transport;GO:0046686|response to cadmium ion;GO:0051412|response to corticosterone;","GO:0005730|nucleolus;GO:0005737|cytoplasm;GO:0005783|endoplasmic reticulum;GO:0005789|endoplasmic reticulum membrane;GO:0016021|integral component of membrane;GO:0031966|mitochondrial membrane;GO:0043231|intracellular membrane-bounded organelle;GO:0045171|intercellular bridge;","GO:0003854|3-beta-hydroxy-delta5-steroid dehydrogenase activity;GO:0004769|steroid delta-isomerase activity;GO:0016616|oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor;GO:0016853|isomerase activity;GO:0030283|testosterone dehydrogenase [NAD(P)] activity;GO:0102294|cholesterol dehydrogenase activity;","K00070","HSD3B; 3beta-hydroxy-Delta5-steroid dehydrogenase / steroid Delta-isomerase [EC:1.1.1.145 5.3.3.1]"]
["ENSRNOG00000001232",236,8.05187485829647,19.855923400559,102,3.43419277110324,8.4687193735406,2.34461936034819,1.22935372593403,{"v":6.12484405224886e-14,"d":"6.12E-14"},{"v":6.20426182445841e-13,"d":"6.20E-13"},"up","yes","Slc19a1","protein_coding","chr20:11584411-11601972:-","gi|78126144|ref|NP_001030309.1|",2507,0,"folate transporter 1 [Rattus norvegicus]","gi|225903393|ref|NM_017299.2|",2410,0,"Rattus norvegicus solute carrier family 19 member 1 (Slc19a1), transcript variant 1, mRNA","Q62866",966,0,"Folate transporter 1",".",".",".",".","pfam01770","Folate_carrier","Reduced folate carrier. The reduced folate carrier (a transmembrane glycoprotein) transports reduced folate into mammalian cells via the carrier mediated mechanism (as opposed to the receptor mediated mechanism) it also transports cytotoxic folate analogues used in chemotherapy, such as methotrexate (MTX). Mammalian cells have an absolute requirement for exogenous folates which are needed for growth, and biosynthesis of macromolecules.","GO:0007565|female pregnancy;GO:0015711|organic anion transport;GO:0015884|folic acid transport;GO:0051958|methotrexate transport;GO:0055085|transmembrane transport;GO:0098838|folate transmembrane transport;GO:1904447|folate import across plasma membrane;","GO:0005886|plasma membrane;GO:0005887|integral component of plasma membrane;GO:0016323|basolateral plasma membrane;GO:0016324|apical plasma membrane;GO:0031526|brush border membrane;","GO:0005542|folic acid binding;GO:0008514|organic anion transmembrane transporter activity;GO:0008517|folic acid transmembrane transporter activity;GO:0008518|folate:anion antiporter activity;GO:0015350|methotrexate transmembrane transporter activity;GO:0061507|cyclic-GMP-AMP binding;","K14609","SLC19A1, RFC1; solute carrier family 19 (folate transporter), member 1"]
["ENSRNOG00000032339",340,11.2622013148773,28.6059913397885,147,4.80508625872498,12.2049190971614,2.34380835399732,1.22885460984502,{"v":2.14238168149346e-19,"d":"2.14E-19"},{"v":3.16481793133709E-18,"d":"3.16E-18"},"up","yes","Rasl12","protein_coding","chr8:65917840-65932741:+","gi|157823221|ref|NP_001101632.1|",1412,0,"ras-like protein family member 12 [Rattus norvegicus]","gi|157823220|ref|NM_001108162.1|",2446,0,"Rattus norvegicus RAS-like, family 12 (Rasl12), mRNA","Q08AT1",541,0,"Ras-like protein family member 12","SPAC17H9.09c",100,{"v":1E-22,"d":"1.00E-22"},"COG1100","pfam00071","Ras","Ras family. Includes sub-families Ras, Rab, Rac, Ral, Ran, Rap Ypt1 and more. Shares P-loop motif with GTP_EFTU, arf and myosin_head. See pfam00009 pfam00025, pfam00063. As regards Rab GTPases, these are important regulators of vesicle formation, motility and fusion. They share a fold in common with all Ras GTPases: this is a six-stranded beta-sheet surrounded by five alpha-helices.","GO:0007165|signal transduction;","GO:0005886|plasma membrane;","GO:0003924|GTPase activity;GO:0005525|GTP binding;GO:0019003|GDP binding;","K07854","RASL12, RIS; Ras-like protein family member 12"]
["ENSRNOG00000006723",473,7.85550376426463,39.7959820697646,205,3.35974445471893,17.0204654076061,2.33812537534846,1.22535229237763,{"v":3.03493438581164E-26,"d":"3.03E-26"},{"v":6.48482383162256e-25,"d":"6.48E-25"},"up","yes","Itga11","protein_coding","chr8:63146001-63254407:+","gi|672062052|ref|XP_008764500.1|",6362,0,"PREDICTED: integrin alpha-11 isoform X2 [Rattus norvegicus]","gi|672062051|ref|XM_008766278.1|",4913,0,"PREDICTED: Rattus norvegicus integrin, alpha 11 (Itga11), transcript variant X2, mRNA","P61622",2385,0,"Integrin alpha-11",".",".",".",".","pfam08441","Integrin_alpha2","Integrin alpha. This domain is found in integrin alpha and integrin alpha precursors to the C terminus of a number of pfam01839 repeats and to the N-terminus of the pfam00357 cytoplasmic region. This region is composed of three immunoglobulin-like domains.","GO:0006929|substrate-dependent cell migration;GO:0007160|cell-matrix adhesion;GO:0007229|integrin-mediated signaling pathway;GO:0008150|biological_process;GO:0033627|cell adhesion mediated by integrin;GO:0038065|collagen-activated signaling pathway;","GO:0005575|cellular_component;GO:0005925|focal adhesion;GO:0034681|integrin alpha11-beta1 complex;","GO:0003674|molecular_function;GO:0005518|collagen binding;GO:0038064|collagen receptor activity;GO:0046872|metal ion binding;GO:0098639|collagen binding involved in cell-matrix adhesion;","K06587","ITGA11; integrin alpha 11"]
["ENSRNOG00000012660",2608,62.0369750155236,219.424780629907,1135,26.6427084240232,94.2352596957704,2.32847854760839,1.21938759059648,{"v":1.0896188007741e-135,"d":"1.09E-135"},{"v":1.55677796422856e-133,"d":"1.56E-133"},"up","yes","Postn","protein_coding","chr2:138527696-138559099:+","gi|564336409|ref|XP_006232397.1|",4144,0,"PREDICTED: periostin isoform X1 [Rattus norvegicus]","gi|672042357|ref|XM_006232335.2|",3278,0,"PREDICTED: Rattus norvegicus periostin, osteoblast specific factor (Postn), transcript variant X1, mRNA","Q62009",1575,0,"Periostin","all4647",79,{"v":1e-15,"d":"1.00E-15"},"COG2335","pfam02469","Fasciclin","Fasciclin domain. This extracellular domain is found repeated four times in grasshopper fasciclin I as well as in proteins from mammals, sea urchins, plants, yeast and bacteria.","GO:0001666|response to hypoxia;GO:0001953|negative regulation of cell-matrix adhesion;GO:0003073|regulation of systemic arterial blood pressure;GO:0007155|cell adhesion;GO:0008593|regulation of Notch signaling pathway;GO:0009612|response to mechanical stimulus;GO:0009888|tissue development;GO:0014850|response to muscle activity;GO:0014911|positive regulation of smooth muscle cell migration;GO:0030198|extracellular matrix organization;GO:0032355|response to estradiol;GO:0042060|wound healing;GO:0044344|cellular response to fibroblast growth factor stimulus;GO:0071307|cellular response to vitamin K;GO:0071356|cellular response to tumor necrosis factor;GO:0071560|cellular response to transforming growth factor beta stimulus;GO:1900025|negative regulation of substrate adhesion-dependent cell spreading;GO:1990138|neuron projection extension;GO:1990523|bone regeneration;GO:2000343|positive regulation of chemokine (C-X-C motif) ligand 2 production;","GO:0005615|extracellular space;GO:0005737|cytoplasm;GO:0005802|trans-Golgi network;GO:0031012|extracellular matrix;GO:0031594|neuromuscular junction;GO:0062023|collagen-containing extracellular matrix;","GO:0003674|molecular_function;GO:0008201|heparin binding;GO:0046872|metal ion binding;GO:0050839|cell adhesion molecule binding;","K24790","POSTN; periostin"]
["ENSRNOG00000021795",244,6.24171649429327,20.5290055497305,109,2.75156764889478,9.04990599721495,2.26842196549315,1.18168903132964,{"v":1.39834745310023e-13,"d":"1.40E-13"},{"v":1.36868381342659e-12,"d":"1.37E-12"},"up","yes","Fam227a","protein_coding","chr7:111174362-111216483:-","gi|256000825|ref|NP_001124053.2|",3181,0,"protein FAM227A [Rattus norvegicus]","gi|686661133|ref|NM_001130581.3|",3219,0,"Rattus norvegicus family with sequence similarity 227, member A (Fam227a), mRNA",".",".",".",".",".",".",".",".","pfam14922","FWWh","Protein of unknown function. This is a family of eukaryotic proteins. Most members carry a highly distinctive, conserved sequence motif of FWWh, where h represents a hydrophobic residue. The function of the family is not known.",".",".",".",".","."]
["ENSRNOG00000017783",466,9.1690914848549,39.2070351892395,213,4.13579950697038,17.6846786918053,2.21700579764602,1.14861254297212,{"v":1.63935451433188e-23,"d":"1.64E-23"},{"v":3.06499528082962e-22,"d":"3.06E-22"},"up","yes","Sfrp1","protein_coding","chr16:68575763-68614286:-","gi|149057790|gb|EDM09033.1|",1304,{"v":3e-164,"d":"3.00E-164"},"secreted frizzled-related protein 1 [Rattus norvegicus]","gi|453040306|ref|NM_001276712.1|",3875,0,"Rattus norvegicus secreted frizzled-related protein 1 (Sfrp1), mRNA","Q8C4U3",505,{"v":3e-165,"d":"3.00E-165"},"Secreted frizzled-related protein 1",".",".",".",".","pfam01392","Fz","Fz domain. Also known as the CRD (cysteine rich domain), the C6 box in MuSK receptor. This domain of unknown function has been independently identified by several groups. The domain contains 10 conserved cysteines.","GO:0001649|osteoblast differentiation;GO:0001657|ureteric bud development;GO:0001756|somitogenesis;GO:0001843|neural tube closure;GO:0002244|hematopoietic progenitor cell differentiation;GO:0006508|proteolysis;GO:0008284|positive regulation of cell proliferation;GO:0008285|negative regulation of cell proliferation;GO:0008584|male gonad development;GO:0008585|female gonad development;GO:0009267|cellular response to starvation;GO:0009410|response to xenobiotic stimulus;GO:0009950|dorsal/ventral axis specification;GO:0009952|anterior/posterior pattern specification;GO:0010564|regulation of cell cycle process;GO:0010629|negative regulation of gene expression;GO:0010719|negative regulation of epithelial to mesenchymal transition;GO:0010975|regulation of neuron projection development;GO:0014034|neural crest cell fate commitment;GO:0014070|response to organic cyclic compound;GO:0021915|neural tube development;GO:0030097|hemopoiesis;GO:0030177|positive regulation of Wnt signaling pathway;GO:0030178|negative regulation of Wnt signaling pathway;GO:0030278|regulation of ossification;GO:0030279|negative regulation of ossification;GO:0030307|positive regulation of cell growth;GO:0030308|negative regulation of cell growth;GO:0030336|negative regulation of cell migration;GO:0030514|negative regulation of BMP signaling pathway;GO:0033689|negative regulation of osteoblast proliferation;GO:0035019|somatic stem cell population maintenance;GO:0035567|non-canonical Wnt signaling pathway;GO:0043065|positive regulation of apoptotic process;GO:0043066|negative regulation of apoptotic process;GO:0043508|negative regulation of JUN kinase activity;GO:0044344|cellular response to fibroblast growth factor stimulus;GO:0044345|stromal-epithelial cell signaling involved in prostate gland development;GO:0045578|negative regulation of B cell differentiation;GO:0045600|positive regulation of fat cell differentiation;GO:0045668|negative regulation of osteoblast differentiation;GO:0045671|negative regulation of osteoclast differentiation;GO:0045880|positive regulation of smoothened signaling pathway;GO:0045892|negative regulation of transcription, DNA-templated;GO:0045893|positive regulation of transcription, DNA-templated;GO:0046546|development of primary male sexual characteristics;GO:0046676|negative regulation of insulin secretion;GO:0046851|negative regulation of bone remodeling;GO:0048147|negative regulation of fibroblast proliferation;GO:0048546|digestive tract morphogenesis;GO:0050679|positive regulation of epithelial cell proliferation;GO:0050680|negative regulation of epithelial cell proliferation;GO:0050732|negative regulation of peptidyl-tyrosine phosphorylation;GO:0060070|canonical Wnt signaling pathway;GO:0060071|Wnt signaling pathway, planar cell polarity pathway;GO:0060218|hematopoietic stem cell differentiation;GO:0060346|bone trabecula formation;GO:0060527|prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis;GO:0060687|regulation of branching involved in prostate gland morphogenesis;GO:0060766|negative regulation of androgen receptor signaling pathway;GO:0071305|cellular response to vitamin D;GO:0071347|cellular response to interleukin-1;GO:0071356|cellular response to tumor necrosis factor;GO:0071363|cellular response to growth factor stimulus;GO:0071380|cellular response to prostaglandin E stimulus;GO:0071391|cellular response to estrogen stimulus;GO:0071392|cellular response to estradiol stimulus;GO:0071456|cellular response to hypoxia;GO:0071481|cellular response to X-ray;GO:0071504|cellular response to heparin;GO:0071542|dopaminergic neuron differentiation;GO:0071560|cellular response to transforming growth factor beta stimulus;GO:0071773|cellular response to BMP stimulus;GO:0090090|negative regulation of canonical Wnt signaling pathway;GO:0090175|regulation of establishment of planar polarity;GO:0090179|planar cell polarity pathway involved in neural tube closure;GO:0090244|Wnt signaling pathway involved in somitogenesis;GO:0090246|convergent extension involved in somitogenesis;GO:0090263|positive regulation of canonical Wnt signaling pathway;GO:1902043|positive regulation of extrinsic apoptotic signaling pathway via death domain receptors;GO:1904956|regulation of midbrain dopaminergic neuron differentiation;GO:2000041|negative regulation of planar cell polarity pathway involved in axis elongation;GO:2000052|positive regulation of non-canonical Wnt signaling pathway;GO:2000054|negative regulation of Wnt signaling pathway involved in dorsal/ventral axis specification;GO:2000080|negative regulation of canonical Wnt signaling pathway involved in controlling type B pancreatic cell proliferation;GO:2000270|negative regulation of fibroblast apoptotic process;GO:2000271|positive regulation of fibroblast apoptotic process;GO:2001238|positive regulation of extrinsic apoptotic signaling pathway;","GO:0005575|cellular_component;GO:0005615|extracellular space;GO:0005829|cytosol;GO:0009986|cell surface;GO:0062023|collagen-containing extracellular matrix;","GO:0003674|molecular_function;GO:0004197|cysteine-type endopeptidase activity;GO:0005109|frizzled binding;GO:0008201|heparin binding;GO:0017147|Wnt-protein binding;GO:0042802|identical protein binding;","K02166","SFRP1; secreted frizzled-related protein 1"]
["ENSRNOG00000014311",2629,53.9491759198737,221.191621271482,1218,24.6649932973994,101.126472519337,2.18727713684649,1.1291360272554,{"v":3.165094866589E-121,"d":"3.17E-121"},{"v":3.93480211881437e-119,"d":"3.93E-119"},"up","yes","Slc7a8","protein_coding","chr15:28183015-28242717:-","gi|16758188|ref|NP_445894.1|",2472,0,"large neutral amino acids transporter small subunit 2 [Rattus norvegicus]","gi|16758187|ref|NM_053442.1|",4100,0,"Rattus norvegicus solute carrier family 7 (amino acid transporter light chain, L system), member 8 (Slc7a8), mRNA","Q9WVR6",956,0,"Large neutral amino acids transporter small subunit 2","BS_ykbA",139,{"v":1e-33,"d":"1.00E-33"},"COG0531","pfam13520","AA_permease_2","Amino acid permease.","GO:0003333|amino acid transmembrane transport;GO:0006865|amino acid transport;GO:0015695|organic cation transport;GO:0015804|neutral amino acid transport;GO:0015807|L-amino acid transport;GO:0015816|glycine transport;GO:0015820|leucine transport;GO:0015827|tryptophan transport;GO:0015829|valine transport;GO:0035524|proline transmembrane transport;GO:0070327|thyroid hormone transport;GO:0089718|amino acid import across plasma membrane;GO:0098713|leucine import across plasma membrane;GO:1901998|toxin transport;GO:1903801|L-leucine import across plasma membrane;GO:1904273|L-alanine import across plasma membrane;","GO:0005737|cytoplasm;GO:0005886|plasma membrane;GO:0009925|basal plasma membrane;GO:0016021|integral component of membrane;GO:0016323|basolateral plasma membrane;GO:0016324|apical plasma membrane;GO:0031528|microvillus membrane;","GO:0015101|organic cation transmembrane transporter activity;GO:0015171|amino acid transmembrane transporter activity;GO:0015175|neutral amino acid transmembrane transporter activity;GO:0015179|L-amino acid transmembrane transporter activity;GO:0015180|L-alanine transmembrane transporter activity;GO:0015187|glycine transmembrane transporter activity;GO:0015190|L-leucine transmembrane transporter activity;GO:0015349|thyroid hormone transmembrane transporter activity;GO:0019534|toxin transmembrane transporter activity;GO:0042605|peptide antigen binding;","K13781","SLC7A8, LAT2; solute carrier family 7 (L-type amino acid transporter), member 8"]
["ENSRNOG00000069024",1754,155.013929838077,147.57326120585,814,70.9912832639443,67.5837016672749,2.18356286449618,1.12668406672217,{"v":3.06632897572034e-81,"d":"3.07E-81"},{"v":2.38638508341894e-79,"d":"2.39E-79"},"up","yes","ENSRNOG00000069024","protein_coding","chr10:16681808-16683120:+","gi|537145630|gb|ERE69523.1|",899,{"v":3e-118,"d":"3.00E-118"},"dual specificity protein phosphatase 1-like protein [Cricetulus griseus]","gi|134142819|ref|NM_053769.3|",590,0,"Rattus norvegicus dual specificity phosphatase 1 (Dusp1), mRNA","Q64623",353,{"v":2E-118,"d":"2.00E-118"},"Dual specificity protein phosphatase 1","YBR276c_2",67,{"v":3e-12,"d":"3.00E-12"},"COG2453","pfam00782","DSPc","Dual specificity phosphatase, catalytic domain. Ser/Thr and Tyr protein phosphatases. The enzyme's tertiary fold is highly similar to that of tyrosine-specific phosphatases, except for a \"recognition\" region.",".",".",".",".","."]
["ENSRNOG00000004649",476,21.4391798049806,40.0483878757039,222,9.86719413090446,18.4319186365295,2.17277369032725,1.11953791550152,{"v":4.44222795960512e-23,"d":"4.44E-23"},{"v":8.14624051725867e-22,"d":"8.15E-22"},"up","yes","Il1b","protein_coding","chr3:116577010-116583415:-","gi|158186736|ref|NP_113700.2|",1243,{"v":6e-165,"d":"6.00E-165"},"interleukin-1 beta precursor [Rattus norvegicus]","gi|158186735|ref|NM_031512.2|",1209,0,"Rattus norvegicus interleukin 1 beta (Il1b), mRNA","Q63264",479,{"v":4E-165,"d":"4.00E-165"},"Interleukin-1 beta",".",".",".",".","pfam00340","IL1","Interleukin-1 / 18. This family includes interleukin-1 and interleukin-18.","GO:0000122|negative regulation of transcription by RNA polymerase II;GO:0000165|MAPK cascade;GO:0001660|fever generation;GO:0001666|response to hypoxia;GO:0001934|positive regulation of protein phosphorylation;GO:0002439|chronic inflammatory response to antigenic stimulus;GO:0002526|acute inflammatory response;GO:0006954|inflammatory response;GO:0006955|immune response;GO:0007204|positive regulation of cytosolic calcium ion concentration;GO:0007584|response to nutrient;GO:0007611|learning or memory;GO:0007613|memory;GO:0008284|positive regulation of cell proliferation;GO:0008285|negative regulation of cell proliferation;GO:0009408|response to heat;GO:0009410|response to xenobiotic stimulus;GO:0009743|response to carbohydrate;GO:0010193|response to ozone;GO:0010243|response to organonitrogen compound;GO:0010332|response to gamma radiation;GO:0010573|vascular endothelial growth factor production;GO:0010575|positive regulation of vascular endothelial growth factor production;GO:0010628|positive regulation of gene expression;GO:0010629|negative regulation of gene expression;GO:0010718|positive regulation of epithelial to mesenchymal transition;GO:0010829|negative regulation of glucose transmembrane transport;GO:0010942|positive regulation of cell death;GO:0014050|negative regulation of glutamate secretion;GO:0014070|response to organic cyclic compound;GO:0019221|cytokine-mediated signaling pathway;GO:0030213|hyaluronan biosynthetic process;GO:0030335|positive regulation of cell migration;GO:0030593|neutrophil chemotaxis;GO:0030728|ovulation;GO:0030730|sequestering of triglyceride;GO:0031394|positive regulation of prostaglandin biosynthetic process;GO:0031622|positive regulation of fever generation;GO:0031663|lipopolysaccharide-mediated signaling pathway;GO:0032308|positive regulation of prostaglandin secretion;GO:0032355|response to estradiol;GO:0032496|response to lipopolysaccharide;GO:0032722|positive regulation of chemokine production;GO:0032725|positive regulation of granulocyte macrophage colony-stimulating factor production;GO:0032729|positive regulation of interferon-gamma production;GO:0032743|positive regulation of interleukin-2 production;GO:0032755|positive regulation of interleukin-6 production;GO:0032757|positive regulation of interleukin-8 production;GO:0032874|positive regulation of stress-activated MAPK cascade;GO:0033092|positive regulation of immature T cell proliferation in thymus;GO:0033198|response to ATP;GO:0033280|response to vitamin D;GO:0033591|response to L-ascorbic acid;GO:0034116|positive regulation of heterotypic cell-cell adhesion;GO:0035176|social behavior;GO:0035234|ectopic germ cell programmed cell death;GO:0035505|positive regulation of myosin light chain kinase activity;GO:0035634|response to stilbenoid;GO:0035902|response to immobilization stress;GO:0042060|wound healing;GO:0042102|positive regulation of T cell proliferation;GO:0043065|positive regulation of apoptotic process;GO:0043122|regulation of I-kappaB kinase/NF-kappaB signaling;GO:0043123|positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0043278|response to morphine;GO:0043406|positive regulation of MAP kinase activity;GO:0043407|negative regulation of MAP kinase activity;GO:0043434|response to peptide hormone;GO:0043491|protein kinase B signaling;GO:0043507|positive regulation of JUN kinase activity;GO:0043525|positive regulation of neuron apoptotic process;GO:0045429|positive regulation of nitric oxide biosynthetic process;GO:0045471|response to ethanol;GO:0045665|negative regulation of neuron differentiation;GO:0045687|positive regulation of glial cell differentiation;GO:0045766|positive regulation of angiogenesis;GO:0045833|negative regulation of lipid metabolic process;GO:0045840|positive regulation of mitotic nuclear division;GO:0045893|positive regulation of transcription, DNA-templated;GO:0045917|positive regulation of complement activation;GO:0045944|positive regulation of transcription by RNA polymerase II;GO:0046330|positive regulation of JNK cascade;GO:0046627|negative regulation of insulin receptor signaling pathway;GO:0048143|astrocyte activation;GO:0048711|positive regulation of astrocyte differentiation;GO:0050691|regulation of defense response to virus by host;GO:0050729|positive regulation of inflammatory response;GO:0050766|positive regulation of phagocytosis;GO:0050767|regulation of neurogenesis;GO:0050768|negative regulation of neurogenesis;GO:0050796|regulation of insulin secretion;GO:0050805|negative regulation of synaptic transmission;GO:0050900|leukocyte migration;GO:0050995|negative regulation of lipid catabolic process;GO:0050996|positive regulation of lipid catabolic process;GO:0050999|regulation of nitric-oxide synthase activity;GO:0051044|positive regulation of membrane protein ectodomain proteolysis;GO:0051091|positive regulation of DNA-binding transcription factor activity;GO:0051092|positive regulation of NF-kappaB transcription factor activity;GO:0051384|response to glucocorticoid;GO:0051781|positive regulation of cell division;GO:0060252|positive regulation of glial cell proliferation;GO:0060559|positive regulation of calcidiol 1-monooxygenase activity;GO:0070164|negative regulation of adiponectin secretion;GO:0070372|regulation of ERK1 and ERK2 cascade;GO:0070374|positive regulation of ERK1 and ERK2 cascade;GO:0070487|monocyte aggregation;GO:0070498|interleukin-1-mediated signaling pathway;GO:0070555|response to interleukin-1;GO:0071222|cellular response to lipopolysaccharide;GO:0071236|cellular response to antibiotic;GO:0071260|cellular response to mechanical stimulus;GO:0071310|cellular response to organic substance;GO:0071333|cellular response to glucose stimulus;GO:0071396|cellular response to lipid;GO:0071398|cellular response to fatty acid;GO:0071407|cellular response to organic cyclic compound;GO:0071466|cellular response to xenobiotic stimulus;GO:0071548|response to dexamethasone;GO:0071639|positive regulation of monocyte chemotactic protein-1 production;GO:0090023|positive regulation of neutrophil chemotaxis;GO:0097192|extrinsic apoptotic signaling pathway in absence of ligand;GO:1900745|positive regulation of p38MAPK cascade;GO:1901224|positive regulation of NIK/NF-kappaB signaling;GO:1902680|positive regulation of RNA biosynthetic process;GO:1903140|regulation of establishment of endothelial barrier;GO:1903597|negative regulation of gap junction assembly;GO:2000173|negative regulation of branching morphogenesis of a nerve;GO:2000178|negative regulation of neural precursor cell proliferation;GO:2000556|positive regulation of T-helper 1 cell cytokine production;GO:2001240|negative regulation of extrinsic apoptotic signaling pathway in absence of ligand;","GO:0005576|extracellular region;GO:0005615|extracellular space;GO:0005764|lysosome;GO:0005829|cytosol;GO:0030141|secretory granule;GO:0031982|vesicle;","GO:0005125|cytokine activity;GO:0005149|interleukin-1 receptor binding;GO:0005178|integrin binding;GO:0019904|protein domain specific binding;","K04519","IL1B; interleukin 1 beta"]
["ENSRNOG00000006368",627,13.5785877583824,52.7528134413159,294,6.28309863431735,24.4098381943229,2.16112917346518,1.11178530650936,{"v":1.44717937883208E-29,"d":"1.45E-29"},{"v":3.57963124940997e-28,"d":"3.58E-28"},"up","yes","Lrrn3","protein_coding","chr6:58489010-58520330:-","gi|51980290|gb|AAH81791.1|",3594,0,"Leucine rich repeat neuronal 3 [Rattus norvegicus]","gi|13540674|ref|NM_030856.1|",3032,0,"Rattus norvegicus leucine rich repeat neuronal 3 (Lrrn3), mRNA","Q9ESY6",1382,0,"Leucine-rich repeat neuronal protein 3","alr0124_1",58.5,{"v":8e-08,"d":"8.00E-08"},"COG4886","pfam13855","LRR_8","Leucine rich repeat.","GO:0001934|positive regulation of protein phosphorylation;GO:0051965|positive regulation of synapse assembly;","GO:0005615|extracellular space;GO:0005886|plasma membrane;GO:0016021|integral component of membrane;GO:0030131|clathrin adaptor complex;GO:0031012|extracellular matrix;","GO:0044877|protein-containing complex binding;","K24492","LRRN1_2_3; leucine-rich repeat neuronal protein 1/2/3"]
["ENSRNOG00000016758",995,16.8813454936891,83.7145923032046,467,7.81880428818954,38.7734504651319,2.15906996408501,1.11040999426503,{"v":7.93555902639053e-46,"d":"7.94E-46"},{"v":3.48455980749642E-44,"d":"3.48E-44"},"up","yes","Loxl2","protein_coding","chr15:44683880-44773067:+","gi|201066363|ref|NP_001099517.2|",3926,0,"lysyl oxidase homolog 2 precursor [Rattus norvegicus]","gi|201066362|ref|NM_001106047.2|",2566,0,"Rattus norvegicus lysyl oxidase-like 2 (Loxl2), mRNA","B5DF27",1514,0,"Lysyl oxidase homolog 2",".",".",".",".","pfam01186","Lysyl_oxidase","Lysyl oxidase.","GO:0000122|negative regulation of transcription by RNA polymerase II;GO:0001666|response to hypoxia;GO:0001837|epithelial to mesenchymal transition;GO:0001935|endothelial cell proliferation;GO:0002040|sprouting angiogenesis;GO:0006464|cellular protein modification process;GO:0006897|endocytosis;GO:0010718|positive regulation of epithelial to mesenchymal transition;GO:0018057|peptidyl-lysine oxidation;GO:0030199|collagen fibril organization;GO:0032332|positive regulation of chondrocyte differentiation;GO:0043542|endothelial cell migration;GO:0045892|negative regulation of transcription, DNA-templated;GO:0046688|response to copper ion;GO:0070828|heterochromatin organization;GO:1902455|negative regulation of stem cell population maintenance;","GO:0000785|chromatin;GO:0005604|basement membrane;GO:0005615|extracellular space;GO:0005634|nucleus;GO:0005654|nucleoplasm;GO:0005783|endoplasmic reticulum;GO:0016020|membrane;","GO:0004720|protein-lysine 6-oxidase activity;GO:0005044|scavenger receptor activity;GO:0005507|copper ion binding;GO:0005509|calcium ion binding;GO:0070492|oligosaccharide binding;","K00280","LOXL2_3_4; lysyl oxidase-like protein 2/3/4 [EC:1.4.3.-]"]
["ENSRNOG00000049918",790,30.4893863443509,66.4668622306851,371,14.1297665388719,30.8028910547408,2.15781246353028,1.10956948498735,{"v":1.06242312334711e-36,"d":"1.06E-36"},{"v":3.44748502708794e-35,"d":"3.45E-35"},"up","yes","Lrg1","protein_coding","chr9:947516-949813:-","gi|149028218|gb|EDL83656.1|",1560,0,"rCG44999 [Rattus norvegicus]","gi|57528406|ref|NM_001009717.1|",1264,0,"Rattus norvegicus leucine-rich alpha-2-glycoprotein 1 (Lrg1), mRNA","P02750",357,{"v":5e-115,"d":"5.00E-115"},"Leucine-rich alpha-2-glycoprotein","SPy1798",66.6,{"v":2e-10,"d":"2.00E-10"},"COG4886","pfam13855","LRR_8","Leucine rich repeat.","GO:0001938|positive regulation of endothelial cell proliferation;GO:0009617|response to bacterium;GO:0030511|positive regulation of transforming growth factor beta receptor signaling pathway;GO:0045766|positive regulation of angiogenesis;GO:0050873|brown fat cell differentiation;","GO:0005615|extracellular space;GO:0043231|intracellular membrane-bounded organelle;","GO:0005160|transforming growth factor beta receptor binding;","K25431","LRG1; leucine-rich alpha-2-glycoprotein"]
["ENSRNOG00000014532",579,19.0737355310442,48.7143205462869,272,8.84230683742166,22.5832516627749,2.15709948565932,1.10909271528258,{"v":2.49938678341899e-27,"d":"2.50E-27"},{"v":5.61630597561511e-26,"d":"5.62E-26"},"up","yes","Lbp","protein_coding","chr3:146954015-146981586:+","gi|139948891|ref|NP_058904.2|",2400,0,"lipopolysaccharide-binding protein precursor [Rattus norvegicus]","gi|510714|gb|L32132.1|RATLPSBP",2389,0,"Rat lipopolysaccharide binding protein mRNA, complete cds","Q63313",924,0,"Lipopolysaccharide-binding protein",".",".",".",".","pfam02886","LBP_BPI_CETP_C","LBP / BPI / CETP family, C-terminal domain. The N and C terminal domains of the LBP/BPI/CETP family are structurally similar.","GO:0001889|liver development;GO:0002232|leukocyte chemotaxis involved in inflammatory response;GO:0002281|macrophage activation involved in immune response;GO:0006953|acute-phase response;GO:0015920|lipopolysaccharide transport;GO:0031663|lipopolysaccharide-mediated signaling pathway;GO:0032490|detection of molecule of bacterial origin;GO:0032496|response to lipopolysaccharide;GO:0032720|negative regulation of tumor necrosis factor production;GO:0032722|positive regulation of chemokine production;GO:0032755|positive regulation of interleukin-6 production;GO:0032757|positive regulation of interleukin-8 production;GO:0032760|positive regulation of tumor necrosis factor production;GO:0033036|macromolecule localization;GO:0034145|positive regulation of toll-like receptor 4 signaling pathway;GO:0043032|positive regulation of macrophage activation;GO:0045087|innate immune response;GO:0045919|positive regulation of cytolysis;GO:0050829|defense response to Gram-negative bacterium;GO:0050830|defense response to Gram-positive bacterium;GO:0060100|positive regulation of phagocytosis, engulfment;GO:0060265|positive regulation of respiratory burst involved in inflammatory response;GO:0071222|cellular response to lipopolysaccharide;GO:0071223|cellular response to lipoteichoic acid;GO:0090023|positive regulation of neutrophil chemotaxis;GO:0090559|regulation of membrane permeability;","GO:0005615|extracellular space;GO:0009986|cell surface;GO:0016020|membrane;","GO:0001530|lipopolysaccharide binding;GO:0005102|signaling receptor binding;GO:0070891|lipoteichoic acid binding;GO:0071723|lipopeptide binding;","K05399","LBP; lipopolysaccharide-binding protein"]
["ENSRNOG00000000906",241,8.43452568377341,20.2765997437912,114,3.93720436765369,9.46503929983949,2.14226260467139,1.0991353406089,{"v":4.0377673272232e-12,"d":"4.04E-12"},{"v":3.44182213614171e-11,"d":"3.44E-11"},"up","yes","Medag","protein_coding","chr12:5613208-5634767:-","gi|109495069|ref|XP_341030.3|",1390,0,"PREDICTED: mesenteric estrogen-dependent adipogenesis protein isoform X3 [Rattus norvegicus]","gi|672072217|ref|XM_341029.6|",2404,0,"PREDICTED: Rattus norvegicus mesenteric estrogen-dependent adipogenesis (Medag), transcript variant X3, mRNA","Q14BA6",533,0,"Mesenteric estrogen-dependent adipogenesis protein",".",".",".",".","pfam03251","Tymo_45kd_70kd","Tymovirus 45/70Kd protein. Tymoviruses are single stranded RNA viruses. This family includes a protein of unknown function that has been named based on its molecular weight. Tymoviruses such as the ononis yellow mosaic tymovirus encode only three proteins. Of these two are overlapping this protein overlaps a larger ORF that is thought to be the polymerase.","GO:0045600|positive regulation of fat cell differentiation;","GO:0005737|cytoplasm;",".",".","."]
["ENSRNOG00000043387",615,24.745667248952,51.7431902175586,291,11.5546428564075,24.1607582127481,2.14162112637081,1.098703275862,{"v":1.63459619266547e-28,"d":"1.63E-28"},{"v":3.87307590217392e-27,"d":"3.87E-27"},"up","yes","Cpe","protein_coding","chr16:25030276-25142233:+","gi|55249691|gb|AAH85762.1|",2182,0,"Carboxypeptidase E [Rattus norvegicus]","gi|55249690|gb|BC085762.1|",2090,0,"Rattus norvegicus carboxypeptidase E, mRNA (cDNA clone MGC:93638 IMAGE:7193151), complete cds","P15087",843,0,"Carboxypeptidase E","BH3831",57,{"v":8e-08,"d":"8.00E-08"},"COG2866","pfam00246","Peptidase_M14","Zinc carboxypeptidase.","GO:0003214|cardiac left ventricle morphogenesis;GO:0006518|peptide metabolic process;GO:0016055|Wnt signaling pathway;GO:0016485|protein processing;GO:0016486|peptide hormone processing;GO:0030070|insulin processing;GO:0030072|peptide hormone secretion;GO:0033366|protein localization to secretory granule;GO:0034230|enkephalin processing;GO:0043171|peptide catabolic process;GO:0072657|protein localization to membrane;GO:2000173|negative regulation of branching morphogenesis of a nerve;","GO:0005576|extracellular region;GO:0005615|extracellular space;GO:0005794|Golgi apparatus;GO:0030141|secretory granule;GO:0030425|dendrite;GO:0030658|transport vesicle membrane;GO:0030667|secretory granule membrane;GO:0031045|dense core granule;GO:0043025|neuronal cell body;GO:0043204|perikaryon;GO:0045121|membrane raft;GO:0097060|synaptic membrane;","GO:0004180|carboxypeptidase activity;GO:0004181|metallocarboxypeptidase activity;GO:0005515|protein binding;GO:0008270|zinc ion binding;GO:0019904|protein domain specific binding;GO:0042043|neurexin family protein binding;GO:0050839|cell adhesion molecule binding;GO:0050897|cobalt ion binding;","K01294","CPE; carboxypeptidase E [EC:3.4.17.10]"]
["ENSRNOG00000016351",729,15.4534166901618,61.3346108432524,345,7.21698107359365,28.6441978810932,2.14125775481172,1.09845847120509,{"v":1.77832147021413E-33,"d":"1.78E-33"},{"v":5.22179192150307e-32,"d":"5.22E-32"},"up","yes","Frrs1","protein_coding","chr2:204823025-204895540:+","gi|672016242|ref|XP_008773478.1|",3035,0,"PREDICTED: ferric-chelate reductase 1 isoform X1 [Rattus norvegicus]","gi|672016241|ref|XM_008775256.1|",1886,0,"PREDICTED: Rattus norvegicus ferric-chelate reductase 1 (Frrs1), transcript variant X1, mRNA","Q8K385",1062,0,"Ferric-chelate reductase 1",".",".",".",".","pfam02014","Reeler","Reeler domain.","GO:0006879|cellular iron ion homeostasis;","GO:0016021|integral component of membrane;","GO:0016722|oxidoreductase activity, oxidizing metal ions;",".","."]
["ENSRNOG00000068016",329,3.79340871381084,27.6805033846777,156,1.77499781305819,12.9521590418856,2.13713430287278,1.09567757341668,{"v":6.30994124408579e-16,"d":"6.31E-16"},{"v":7.32146948989924e-15,"d":"7.32E-15"},"up","yes","ENSRNOG00000068016","protein_coding","chr19:21909754-22356833:-","gi|672083970|ref|XP_008770468.1|",1034,{"v":2E-125,"d":"2.00E-125"},"PREDICTED: LOW QUALITY PROTEIN: disks large homolog 5-like isoform X2 [Rattus norvegicus]","gi|425703057|gb|AC246664.5|",2331,0,"Rattus norvegicus Y Chr BAC RNAEX-360A21 (Amplicon Express Rat SHR-Akr BAC library) complete sequence","P11260",79,{"v":7e-14,"d":"7.00E-14"},"LINE-1 retrotransposable element ORF1 protein",".",".",".",".","pfam02994","Transposase_22","L1 transposable element.",".",".",".",".","."]
["ENSRNOG00000006735",996,33.6405971785833,83.7987275718511,473,15.7653996099082,39.2716104282814,2.13382457856893,1.09344157727237,{"v":8.72559565272862e-45,"d":"8.73E-45"},{"v":3.7122691463929e-43,"d":"3.71E-43"},"up","yes","Cdkn2b","protein_coding","chr5:104010680-104019050:-","gi|18677739|ref|NP_570825.1|",665,{"v":5E-79,"d":"5.00E-79"},"cyclin-dependent kinase 4 inhibitor B [Rattus norvegicus]","gi|683523985|ref|NM_130812.3|",2304,0,"Rattus norvegicus cyclin-dependent kinase inhibitor 2B (Cdkn2b), mRNA","P55272",260,{"v":2e-80,"d":"2.00E-80"},"Cyclin-dependent kinase 4 inhibitor B",".",".",".",".","pfam12796","Ank_2","Ankyrin repeats (3 copies).","GO:0000079|regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0000086|G2/M transition of mitotic cell cycle;GO:0001889|liver development;GO:0007568|aging;GO:0008285|negative regulation of cell proliferation;GO:0014070|response to organic cyclic compound;GO:0030219|megakaryocyte differentiation;GO:0030511|positive regulation of transforming growth factor beta receptor signaling pathway;GO:0030858|positive regulation of epithelial cell differentiation;GO:0031668|cellular response to extracellular stimulus;GO:0031670|cellular response to nutrient;GO:0034097|response to cytokine;GO:0042326|negative regulation of phosphorylation;GO:0045736|negative regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0048536|spleen development;GO:0050680|negative regulation of epithelial cell proliferation;GO:0051726|regulation of cell cycle;GO:0060253|negative regulation of glial cell proliferation;GO:0070316|regulation of G0 to G1 transition;GO:0071560|cellular response to transforming growth factor beta stimulus;GO:0090398|cellular senescence;GO:1902807|negative regulation of cell cycle G1/S phase transition;GO:2000134|negative regulation of G1/S transition of mitotic cell cycle;","GO:0005634|nucleus;GO:0005737|cytoplasm;","GO:0003674|molecular_function;GO:0004861|cyclin-dependent protein serine/threonine kinase inhibitor activity;GO:0019901|protein kinase binding;","K04685","CDKN2B, P15, INK4B; cyclin-dependent kinase inhibitor 2B"]
["ENSRNOG00000011951",852,25.5373170241411,71.6832488867641,405,11.979265234267,33.6257975125876,2.13179327151809,1.09206754099753,{"v":1.73496156707423e-38,"d":"1.73E-38"},{"v":6.10587409676682e-37,"d":"6.11E-37"},"up","yes","Plk2","protein_coding","chr2:41969176-41974947:+","gi|625183267|ref|XP_003496249.2|",3420,0,"PREDICTED: serine/threonine-protein kinase PLK2 [Cricetulus griseus]","gi|47481733|gb|BC070878.1|",2708,0,"Rattus norvegicus polo-like kinase 2 (Drosophila), mRNA (cDNA clone MGC:91616 IMAGE:7096750), complete cds","Q9R012",1313,0,"Serine/threonine-protein kinase PLK2",".",".",".",".","pfam00069","Pkinase","Protein kinase domain.","GO:0000082|G1/S transition of mitotic cell cycle;GO:0000278|mitotic cell cycle;GO:0006468|protein phosphorylation;GO:0007052|mitotic spindle organization;GO:0007265|Ras protein signal transduction;GO:0007613|memory;GO:0010508|positive regulation of autophagy;GO:0016525|negative regulation of angiogenesis;GO:0018105|peptidyl-serine phosphorylation;GO:0032092|positive regulation of protein binding;GO:0032436|positive regulation of proteasomal ubiquitin-dependent protein catabolic process;GO:0032465|regulation of cytokinesis;GO:0032486|Rap protein signal transduction;GO:0043066|negative regulation of apoptotic process;GO:0043123|positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0045732|positive regulation of protein catabolic process;GO:0046599|regulation of centriole replication;GO:0048167|regulation of synaptic plasticity;GO:0060291|long-term synaptic potentiation;GO:0060292|long-term synaptic depression;GO:0061000|negative regulation of dendritic spine development;GO:0071866|negative regulation of apoptotic process in bone marrow;GO:0090050|positive regulation of cell migration involved in sprouting angiogenesis;GO:2000773|negative regulation of cellular senescence;","GO:0000785|chromatin;GO:0000922|spindle pole;GO:0005634|nucleus;GO:0005737|cytoplasm;GO:0005813|centrosome;GO:0005814|centriole;GO:0030425|dendrite;","GO:0004674|protein serine/threonine kinase activity;GO:0005515|protein binding;GO:0005524|ATP binding;GO:0043008|ATP-dependent protein binding;GO:0044877|protein-containing complex binding;","K08861","PLK2; polo-like kinase 2 [EC:2.7.11.21]"]
["ENSRNOG00000062679",538,29.604169085535,45.264774531783,256,13.9011282500826,21.2548250943764,2.12962347753024,1.09059838110031,{"v":7.2127909070481e-25,"d":"7.21E-25"},{"v":1.45357224932171e-23,"d":"1.45E-23"},"up","yes","Akr1c13","protein_coding","chr17:65964975-65997591:+","gi|564392048|ref|XP_006254252.1|",1995,0,"PREDICTED: aldo-keto reductase family 1, member C12 isoform X3 [Rattus norvegicus]","gi|672082446|ref|XM_006254190.2|",1406,0,"PREDICTED: Rattus norvegicus aldo-keto reductase family 1, member C12 (Akr1c12), transcript variant X2, mRNA","Q8VC28",573,0,"Aldo-keto reductase family 1 member C13","YOR120w",186,{"v":3e-53,"d":"3.00E-53"},"COG0656","pfam00248","Aldo_ket_red","Aldo/keto reductase family. This family includes a number of K+ ion channel beta chain regulatory domains - these are reported to have oxidoreductase activity.",".",".",".",".","."]
["ENSRNOG00000018785",272,2.6444179653144,22.8847930718308,130,1.24722277192489,10.793465868238,2.12024509561604,1.08423104676557,{"v":3.16153204195336e-13,"d":"3.16E-13"},{"v":3.00534965809916e-12,"d":"3.01E-12"},"up","yes","Slc16a13","protein_coding","chr10:54926760-54937788:-","gi|53850584|ref|NP_001005530.1|",1511,0,"monocarboxylate transporter 13 [Rattus norvegicus]","gi|53850583|ref|NM_001005530.1|",1367,0,"Rattus norvegicus solute carrier family 16, member 13 (Slc16a13), mRNA","Q66HE2",586,0,"Monocarboxylate transporter 13",".",".",".",".","pfam07690","MFS_1","Major Facilitator Superfamily.","GO:0015718|monocarboxylic acid transport;GO:0055085|transmembrane transport;","GO:0000139|Golgi membrane;GO:0005794|Golgi apparatus;GO:0005829|cytosol;GO:0005887|integral component of plasma membrane;GO:0016021|integral component of membrane;","GO:0008028|monocarboxylic acid transmembrane transporter activity;GO:0015293|symporter activity;","K08189","SLC16A13; MFS transporter, MCT family, solute carrier family 16 (monocarboxylic acid transporters), member 13"]
["ENSRNOG00000013578",399,20.928910342848,33.5699721899283,191,9.88659112235498,15.8580921602573,2.1168985430706,1.08195212673028,{"v":1.23929826701873E-18,"d":"1.24E-18"},{"v":1.72430582119079e-17,"d":"1.72E-17"},"up","yes","Trem2","protein_coding","chr9:12647259-12654170:-","gi|564367094|ref|XP_006244487.1|",987,{"v":2e-129,"d":"2.00E-129"},"PREDICTED: triggering receptor expressed on myeloid cells 2 isoform X2 [Rattus norvegicus]","gi|672064257|ref|XM_006244425.2|",982,0,"PREDICTED: Rattus norvegicus triggering receptor expressed on myeloid cells 2 (Trem2), transcript variant X2, mRNA","Q99NH8",322,{"v":2e-106,"d":"2.00E-106"},"Triggering receptor expressed on myeloid cells 2",".",".",".",".","pfam07223","DUF1421","Protein of unknown function (DUF1421). This family represents a conserved region approximately 350 residues long within a number of plant proteins of unknown function.","GO:0001774|microglial cell activation;GO:0001934|positive regulation of protein phosphorylation;GO:0002282|microglial cell activation involved in immune response;GO:0002588|positive regulation of antigen processing and presentation of peptide antigen via MHC class II;GO:0002862|negative regulation of inflammatory response to antigenic stimulus;GO:0002931|response to ischemia;GO:0006910|phagocytosis, recognition;GO:0006911|phagocytosis, engulfment;GO:0007613|memory;GO:0010468|regulation of gene expression;GO:0010507|negative regulation of autophagy;GO:0010628|positive regulation of gene expression;GO:0010822|positive regulation of mitochondrion organization;GO:0010875|positive regulation of cholesterol efflux;GO:0010887|negative regulation of cholesterol storage;GO:0010891|negative regulation of sequestering of triglyceride;GO:0010983|positive regulation of high-density lipoprotein particle clearance;GO:0014067|negative regulation of phosphatidylinositol 3-kinase signaling;GO:0014068|positive regulation of phosphatidylinositol 3-kinase signaling;GO:0019216|regulation of lipid metabolic process;GO:0030316|osteoclast differentiation;GO:0032006|regulation of TOR signaling;GO:0032008|positive regulation of TOR signaling;GO:0032497|detection of lipopolysaccharide;GO:0032499|detection of peptidoglycan;GO:0032675|regulation of interleukin-6 production;GO:0032691|negative regulation of interleukin-1 beta production;GO:0032720|negative regulation of tumor necrosis factor production;GO:0032733|positive regulation of interleukin-10 production;GO:0033674|positive regulation of kinase activity;GO:0034136|negative regulation of toll-like receptor 2 signaling pathway;GO:0034144|negative regulation of toll-like receptor 4 signaling pathway;GO:0034151|regulation of toll-like receptor 6 signaling pathway;GO:0034241|positive regulation of macrophage fusion;GO:0034351|negative regulation of glial cell apoptotic process;GO:0035176|social behavior;GO:0038160|CXCL12-activated CXCR4 signaling pathway;GO:0042742|defense response to bacterium;GO:0043066|negative regulation of apoptotic process;GO:0043124|negative regulation of I-kappaB kinase/NF-kappaB signaling;GO:0043277|apoptotic cell clearance;GO:0045088|regulation of innate immune response;GO:0045672|positive regulation of osteoclast differentiation;GO:0045728|respiratory burst after phagocytosis;GO:0045960|positive regulation of complement activation, classical pathway;GO:0048143|astrocyte activation;GO:0048678|response to axon injury;GO:0050714|positive regulation of protein secretion;GO:0050730|regulation of peptidyl-tyrosine phosphorylation;GO:0050731|positive regulation of peptidyl-tyrosine phosphorylation;GO:0050766|positive regulation of phagocytosis;GO:0050829|defense response to Gram-negative bacterium;GO:0050850|positive regulation of calcium-mediated signaling;GO:0050866|negative regulation of cell activation;GO:0050921|positive regulation of chemotaxis;GO:0055088|lipid homeostasis;GO:0060075|regulation of resting membrane potential;GO:0060100|positive regulation of phagocytosis, engulfment;GO:0061518|microglial cell proliferation;GO:0061889|negative regulation of astrocyte activation;GO:0070269|pyroptosis;GO:0070345|negative regulation of fat cell proliferation;GO:0070374|positive regulation of ERK1 and ERK2 cascade;GO:0070392|detection of lipoteichoic acid;GO:0071223|cellular response to lipoteichoic acid;GO:0071224|cellular response to peptidoglycan;GO:0071333|cellular response to glucose stimulus;GO:0071396|cellular response to lipid;GO:0071456|cellular response to hypoxia;GO:0071640|regulation of macrophage inflammatory protein 1 alpha production;GO:0097028|dendritic cell differentiation;GO:0097062|dendritic spine maintenance;GO:0097242|amyloid-beta clearance;GO:0098657|import into cell;GO:0110089|regulation of hippocampal neuron apoptotic process;GO:0120035|regulation of plasma membrane bounded cell projection organization;GO:0140052|cellular response to oxidised low-density lipoprotein particle stimulus;GO:0150062|complement-mediated synapse pruning;GO:0150076|neuroinflammatory response;GO:0150078|positive regulation of neuroinflammatory response;GO:0150079|negative regulation of neuroinflammatory response;GO:0150094|amyloid-beta clearance by cellular catabolic process;GO:1900015|regulation of cytokine production involved in inflammatory response;GO:1900016|negative regulation of cytokine production involved in inflammatory response;GO:1900223|positive regulation of amyloid-beta clearance;GO:1900226|negative regulation of NLRP3 inflammasome complex assembly;GO:1901076|positive regulation of engulfment of apoptotic cell;GO:1901224|positive regulation of NIK/NF-kappaB signaling;GO:1901800|positive regulation of proteasomal protein catabolic process;GO:1901980|positive regulation of inward rectifier potassium channel activity;GO:1902227|negative regulation of macrophage colony-stimulating factor signaling pathway;GO:1902531|regulation of intracellular signal transduction;GO:1903078|positive regulation of protein localization to plasma membrane;GO:1903082|positive regulation of C-C chemokine receptor CCR7 signaling pathway;GO:1903376|regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway;GO:1903753|negative regulation of p38MAPK cascade;GO:1903980|positive regulation of microglial cell activation;GO:1904093|negative regulation of autophagic cell death;GO:1904141|positive regulation of microglial cell migration;GO:1904646|cellular response to amyloid-beta;GO:1904951|positive regulation of establishment of protein localization;GO:1905291|positive regulation of CAMKK-AMPK signaling cascade;GO:1905581|positive regulation of low-density lipoprotein particle clearance;GO:1905805|excitatory synapse pruning;GO:1905808|positive regulation of synapse pruning;GO:1905907|negative regulation of amyloid fibril formation;GO:2000350|positive regulation of CD40 signaling pathway;GO:2001171|positive regulation of ATP biosynthetic process;","GO:0005886|plasma membrane;GO:0005887|integral component of plasma membrane;GO:0016021|integral component of membrane;GO:0031226|intrinsic component of plasma membrane;GO:0044853|plasma membrane raft;","GO:0001530|lipopolysaccharide binding;GO:0001540|amyloid-beta binding;GO:0001786|phosphatidylserine binding;GO:0004888|transmembrane signaling receptor activity;GO:0005543|phospholipid binding;GO:0008035|high-density lipoprotein particle binding;GO:0008429|phosphatidylethanolamine binding;GO:0019209|kinase activator activity;GO:0030169|low-density lipoprotein particle binding;GO:0034185|apolipoprotein binding;GO:0034186|apolipoprotein A-I binding;GO:0034189|very-low-density lipoprotein particle binding;GO:0038023|signaling receptor activity;GO:0042834|peptidoglycan binding;GO:0044877|protein-containing complex binding;GO:0070891|lipoteichoic acid binding;GO:0071813|lipoprotein particle binding;GO:0097110|scaffold protein binding;GO:0120146|sulfatide binding;GO:1990782|protein tyrosine kinase binding;","K14378","TREM2; triggering receptor expressed on myeloid cells 2"]
["ENSRNOG00000003897",34640,500.334026766106,2914.44570591257,16736,238.546642153623,1389.53419054485,2.09742640788836,1.06862019191083,0,0,"up","yes","Col1a1","protein_coding","chr10:79883622-79900624:+","gi|455975|gb|AAB29425.1|",1373,{"v":8e-171,"d":"8.00E-171"},"type I collagen alpha 1 chain [Mus sp.]","gi|158711703|ref|NM_053304.1|",5825,0,"Rattus norvegicus collagen, type I, alpha 1 (Col1a1), mRNA","P02454",555,{"v":2e-166,"d":"2.00E-166"},"Collagen alpha-1(I) chain",".",".",".",".","pfam01410","COLFI","Fibrillar collagen C-terminal domain. Found at C-termini of fibrillar collagens: Ephydatia muelleri procollagen EMF1 alpha, vertebrate collagens alpha(1)III, alpha(1)II, alpha(2)V etc.","GO:0001501|skeletal system development;GO:0001503|ossification;GO:0001568|blood vessel development;GO:0001649|osteoblast differentiation;GO:0001957|intramembranous ossification;GO:0001958|endochondral ossification;GO:0007584|response to nutrient;GO:0007601|visual perception;GO:0007605|sensory perception of sound;GO:0009410|response to xenobiotic stimulus;GO:0009612|response to mechanical stimulus;GO:0010718|positive regulation of epithelial to mesenchymal transition;GO:0010812|negative regulation of cell-substrate adhesion;GO:0015031|protein transport;GO:0030198|extracellular matrix organization;GO:0030199|collagen fibril organization;GO:0030335|positive regulation of cell migration;GO:0031667|response to nutrient levels;GO:0031960|response to corticosteroid;GO:0032355|response to estradiol;GO:0032964|collagen biosynthetic process;GO:0034504|protein localization to nucleus;GO:0034505|tooth mineralization;GO:0038063|collagen-activated tyrosine kinase receptor signaling pathway;GO:0042060|wound healing;GO:0042542|response to hydrogen peroxide;GO:0043434|response to peptide hormone;GO:0043588|skin development;GO:0043589|skin morphogenesis;GO:0044344|cellular response to fibroblast growth factor stimulus;GO:0044691|tooth eruption;GO:0045893|positive regulation of transcription, DNA-templated;GO:0048545|response to steroid hormone;GO:0048705|skeletal system morphogenesis;GO:0048706|embryonic skeletal system development;GO:0051591|response to cAMP;GO:0055093|response to hyperoxia;GO:0060325|face morphogenesis;GO:0060346|bone trabecula formation;GO:0060351|cartilage development involved in endochondral bone morphogenesis;GO:0071230|cellular response to amino acid stimulus;GO:0071260|cellular response to mechanical stimulus;GO:0071300|cellular response to retinoic acid;GO:0071306|cellular response to vitamin E;GO:0071356|cellular response to tumor necrosis factor;GO:0071364|cellular response to epidermal growth factor stimulus;GO:0071560|cellular response to transforming growth factor beta stimulus;GO:0090263|positive regulation of canonical Wnt signaling pathway;GO:1902617|response to fluoride;GO:1902618|cellular response to fluoride;","GO:0005576|extracellular region;GO:0005581|collagen trimer;GO:0005584|collagen type I trimer;GO:0005615|extracellular space;GO:0005737|cytoplasm;GO:0005783|endoplasmic reticulum;GO:0005794|Golgi apparatus;GO:0030141|secretory granule;GO:0031012|extracellular matrix;","GO:0002020|protease binding;GO:0005201|extracellular matrix structural constituent;GO:0005515|protein binding;GO:0042802|identical protein binding;GO:0046872|metal ion binding;GO:0048407|platelet-derived growth factor binding;","K06236","COL1A; collagen type I alpha"]
["ENSRNOG00000006800",368,5.3576360723116,30.9617788618887,178,2.55731883949361,14.7787455734335,2.09502076533112,1.0669645436343,{"v":5.94227476216154e-17,"d":"5.94E-17"},{"v":7.44536958305204e-16,"d":"7.45E-16"},"up","yes","Pgap4","protein_coding","chr5:63930682-63951716:-","gi|31560202|ref|NP_080220.2|",2107,0,"transmembrane protein 246 [Mus musculus]","gi|672052604|ref|XM_006238159.2|",2264,0,"PREDICTED: Rattus norvegicus transmembrane protein 246 (Tmem246), transcript variant X2, mRNA","Q5EB73",816,0,"Transmembrane protein 246",".",".",".",".","pfam05557","MAD","Mitotic checkpoint protein. This family consists of several eukaryotic mitotic checkpoint (Mitotic arrest deficient or MAD) proteins. The mitotic spindle checkpoint monitors proper attachment of the bipolar spindle to the kinetochores of aligned sister chromatids and causes a cell cycle arrest in prometaphase when failures occur. Multiple components of the mitotic spindle checkpoint have been identified in yeast and higher eukaryotes. In S.cerevisiae, the existence of a Mad1-dependent complex containing Mad2, Mad3, Bub3 and Cdc20 has been demonstrated.","GO:0006506|GPI anchor biosynthetic process;","GO:0000139|Golgi membrane;GO:0016021|integral component of membrane;","GO:0016757|transferase activity, transferring glycosyl groups;",".","."]
["ENSRNOG00000003687",2202,110.015357220578,185.265861559453,1078,53.148895514163,89.5027400458506,2.06994625488052,1.04959330935555,{"v":1.10446071821657e-90,"d":"1.10E-90"},{"v":9.88082907544295e-89,"d":"9.88E-89"},"up","yes","Rgs2","protein_coding","chr13:55798829-55802385:-","gi|16758194|ref|NP_445905.1|",1018,{"v":6e-133,"d":"6.00E-133"},"regulator of G-protein signaling 2 [Rattus norvegicus]","gi|298897112|emb|FQ224353.1|",1632,0,"Rattus norvegicus TL0ACA69YI09 mRNA sequence","Q9JHX0",396,{"v":2e-134,"d":"2.00E-134"},"Regulator of G-protein signaling 2",".",".",".",".","pfam00615","RGS","Regulator of G protein signaling domain. RGS family members are GTPase-activating proteins for heterotrimeric G-protein alpha-subunits.","GO:0001975|response to amphetamine;GO:0007283|spermatogenesis;GO:0007420|brain development;GO:0008277|regulation of G protein-coupled receptor signaling pathway;GO:0010519|negative regulation of phospholipase activity;GO:0010614|negative regulation of cardiac muscle hypertrophy;GO:0010976|positive regulation of neuron projection development;GO:0017148|negative regulation of translation;GO:0030728|ovulation;GO:0043407|negative regulation of MAP kinase activity;GO:0045471|response to ethanol;GO:0045744|negative regulation of G protein-coupled receptor signaling pathway;GO:0050873|brown fat cell differentiation;GO:0055119|relaxation of cardiac muscle;GO:0060087|relaxation of vascular smooth muscle;GO:0060135|maternal process involved in female pregnancy;GO:0060452|positive regulation of cardiac muscle contraction;GO:0061052|negative regulation of cell growth involved in cardiac muscle cell development;GO:0140194|negative regulation of adenylate cyclase-inhibiting adrenergic receptor signaling pathway involved in heart process;GO:1900924|negative regulation of glycine import across plasma membrane;","GO:0005634|nucleus;GO:0005730|nucleolus;GO:0005737|cytoplasm;GO:0005829|cytosol;GO:0005886|plasma membrane;GO:0009898|cytoplasmic side of plasma membrane;GO:0043005|neuron projection;","GO:0001965|G-protein alpha-subunit binding;GO:0005096|GTPase activator activity;GO:0010855|adenylate cyclase inhibitor activity;GO:0048487|beta-tubulin binding;","K18154","RGS2; regulator of G-protein signaling 2"]
["ENSRNOG00000049349",492,22.6571166798286,41.3945521740469,241,10.9520663308718,20.0094251865027,2.06875268970591,1.04876118765296,{"v":1.44497966832665E-21,"d":"1.44E-21"},{"v":2.39724716342109e-20,"d":"2.40E-20"},"up","yes","Tafa5","protein_coding","chr7:118613889-118834353:+","gi|625284690|ref|XP_007634048.1|",845,{"v":2e-103,"d":"2.00E-103"},"PREDICTED: uncharacterized protein LOC103158622 isoform X2 [Cricetulus griseus]","gi|300795380|ref|NM_001191991.1|",1827,0,"Rattus norvegicus family with sequence similarity 19 (chemokine (C-C motif)-like), member A5 (Fam19a5), mRNA","Q91WE9",266,{"v":2e-84,"d":"2.00E-84"},"Protein FAM19A5",".",".",".",".","pfam12020","TAFA","TAFA family. This family of secreted proteins are brain specific and thought to be chemokines. These proteins are found in vertebrates. Proteins in this family are typically between 94 to 133 amino acids in length and contain a number of conserved cysteines.","GO:0007186|G protein-coupled receptor signaling pathway;GO:0061044|negative regulation of vascular wound healing;GO:1904706|negative regulation of vascular smooth muscle cell proliferation;GO:1904753|negative regulation of vascular associated smooth muscle cell migration;","GO:0005615|extracellular space;GO:0005737|cytoplasm;","GO:0001664|G protein-coupled receptor binding;GO:0005125|cytokine activity;GO:0048018|receptor ligand activity;","K25545","TAFA5, FAM19A5; chemokine-like protein TAFA5"]
["ENSRNOG00000016695",3076,81.7435522288186,258.800086356439,1507,39.5202708183942,125.121177411036,2.06839554831117,1.04851210490769,{"v":1.06122649714353e-125,"d":"1.06E-125"},{"v":1.41092028966835E-123,"d":"1.41E-123"},"up","yes","Mmp2","protein_coding","chr19:14154657-14182870:-","gi|146262019|ref|NP_112316.2|",3285,0,"72 kDa type IV collagenase precursor [Rattus norvegicus]","gi|146262018|ref|NM_031054.2|",3040,0,"Rattus norvegicus matrix metallopeptidase 2 (Mmp2), mRNA","P33436",1270,0,"72 kDa type IV collagenase",".",".",".",".","pfam00413","Peptidase_M10","Matrixin. The members of this family are enzymes that cleave peptides. These proteases require zinc for catalysis.","GO:0001525|angiogenesis;GO:0001541|ovarian follicle development;GO:0001542|ovulation from ovarian follicle;GO:0001553|luteinization;GO:0001666|response to hypoxia;GO:0001955|blood vessel maturation;GO:0001957|intramembranous ossification;GO:0006508|proteolysis;GO:0006979|response to oxidative stress;GO:0007162|negative regulation of cell adhesion;GO:0007507|heart development;GO:0007565|female pregnancy;GO:0007566|embryo implantation;GO:0007567|parturition;GO:0007568|aging;GO:0009314|response to radiation;GO:0009410|response to xenobiotic stimulus;GO:0009612|response to mechanical stimulus;GO:0014012|peripheral nervous system axon regeneration;GO:0014823|response to activity;GO:0016477|cell migration;GO:0030198|extracellular matrix organization;GO:0030335|positive regulation of cell migration;GO:0030574|collagen catabolic process;GO:0032526|response to retinoic acid;GO:0034097|response to cytokine;GO:0034614|cellular response to reactive oxygen species;GO:0035094|response to nicotine;GO:0035987|endodermal cell differentiation;GO:0042542|response to hydrogen peroxide;GO:0043065|positive regulation of apoptotic process;GO:0043627|response to estrogen;GO:0045089|positive regulation of innate immune response;GO:0045906|negative regulation of vasoconstriction;GO:0048661|positive regulation of smooth muscle cell proliferation;GO:0048705|skeletal system morphogenesis;GO:0048771|tissue remodeling;GO:0051602|response to electrical stimulus;GO:0055093|response to hyperoxia;GO:0060325|face morphogenesis;GO:0060346|bone trabecula formation;GO:0060740|prostate gland epithelium morphogenesis;GO:0071230|cellular response to amino acid stimulus;GO:0071345|cellular response to cytokine stimulus;GO:0071347|cellular response to interleukin-1;GO:0071392|cellular response to estradiol stimulus;GO:0071492|cellular response to UV-A;GO:0071498|cellular response to fluid shear stress;GO:1904645|response to amyloid-beta;GO:1904707|positive regulation of vascular smooth muscle cell proliferation;","GO:0005615|extracellular space;GO:0005634|nucleus;GO:0005737|cytoplasm;GO:0005739|mitochondrion;GO:0005886|plasma membrane;GO:0030017|sarcomere;GO:0031012|extracellular matrix;","GO:0001968|fibronectin binding;GO:0004175|endopeptidase activity;GO:0004222|metalloendopeptidase activity;GO:0004252|serine-type endopeptidase activity;GO:0005515|protein binding;GO:0008233|peptidase activity;GO:0008237|metallopeptidase activity;GO:0008270|zinc ion binding;","K01398","MMP2; matrix metalloproteinase-2 (gelatinase A) [EC:3.4.24.24]"]
["ENSRNOG00000022772",434,8.14151763490604,36.5147065925535,213,3.94307217208592,17.6846786918053,2.06476505617676,1.04597763076232,{"v":3.91134853330298e-19,"d":"3.91E-19"},{"v":5.65581789457261e-18,"d":"5.66E-18"},"up","yes","Prickle1","protein_coding","chr7:124639142-124658113:-","gi|209915609|ref|NP_955428.1|",4021,0,"prickle-like protein 1 [Rattus norvegicus]","gi|209915608|ref|NM_199396.1|",4485,0,"Rattus norvegicus prickle planar cell polarity protein 1 (Prickle1), mRNA","Q71QF9",1550,0,"Prickle-like protein 1",".",".",".",".","pfam06297","PET","PET Domain. This domain is suggested to be involved in protein-protein interactions. The family is found in conjunction with pfam00412.","GO:0001843|neural tube closure;GO:0006606|protein import into nucleus;GO:0031398|positive regulation of protein ubiquitination;GO:0032436|positive regulation of proteasomal ubiquitin-dependent protein catabolic process;GO:0035904|aorta development;GO:0045892|negative regulation of transcription, DNA-templated;GO:0060976|coronary vasculature development;GO:0090090|negative regulation of canonical Wnt signaling pathway;GO:2000691|negative regulation of cardiac muscle cell myoblast differentiation;","GO:0005634|nucleus;GO:0005829|cytosol;GO:0031965|nuclear membrane;","GO:0005515|protein binding;GO:0008270|zinc ion binding;","K04511","PRICKLE; prickle"]
["ENSRNOG00000063207",350,26.8435223575687,29.4473440262528,172,13.0178537924194,14.2805856102841,2.06205437437008,1.04408237567391,{"v":1.09312275951208e-15,"d":"1.09E-15"},{"v":1.24274989576867E-14,"d":"1.24E-14"},"up","yes","ENSRNOG00000063207","lncRNA","chr10:101905070-101909650:+","gi|149054872|gb|EDM06689.1|",244,{"v":8e-23,"d":"8.00E-23"},"rCG33258, isoform CRA_a [Rattus norvegicus]","gi|672025505|ref|XR_338969.2|",744,0,"PREDICTED: Rattus norvegicus uncharacterized LOC100912247 (LOC100912247), ncRNA",".",".",".",".",".",".",".",".","pfam07183","DUF1403","Protein of unknown function (DUF1403). This family consists of several hypothetical bacterial proteins of around 320 residues in length. Members of this family are mainly found in Rhizobium and Agrobacterium species. The function of this family is unknown.",".",".",".",".","."]
["ENSRNOG00000007539",427,14.301655936317,35.9257597120285,210,6.94092305343576,17.4355987102306,2.06048328532294,1.04298276049805,{"v":9.05029758217918e-19,"d":"9.05E-19"},{"v":1.27029729996412e-17,"d":"1.27E-17"},"up","yes","Rsad2","protein_coding","chr6:43047658-43059699:-","gi|149051031|gb|EDM03204.1|",1839,0,"rCG62278 [Rattus norvegicus]","gi|20302056|ref|NM_138881.1|",2366,0,"Rattus norvegicus radical S-adenosyl methionine domain containing 2 (Rsad2), mRNA","O70600",707,0,"Radical S-adenosyl methionine domain-containing protein 2","BH2526",56.2,{"v":2e-07,"d":"2.00E-07"},"COG2896","pfam04055","Radical_SAM","Radical SAM superfamily. Radical SAM proteins catalyse diverse reactions, including unusual methylations, isomerization, sulphur insertion, ring formation, anaerobic oxidation and protein radical formation.","GO:0001503|ossification;GO:0009615|response to virus;GO:0030278|regulation of ossification;GO:0034157|positive regulation of toll-like receptor 7 signaling pathway;GO:0034165|positive regulation of toll-like receptor 9 signaling pathway;GO:0035710|CD4-positive, alpha-beta T cell activation;GO:0043367|CD4-positive, alpha-beta T cell differentiation;GO:0045071|negative regulation of viral genome replication;GO:0045087|innate immune response;GO:0050709|negative regulation of protein secretion;GO:0050778|positive regulation of immune response;GO:0051607|defense response to virus;GO:2000553|positive regulation of T-helper 2 cell cytokine production;","GO:0001650|fibrillar center;GO:0005739|mitochondrion;GO:0005741|mitochondrial outer membrane;GO:0005743|mitochondrial inner membrane;GO:0005783|endoplasmic reticulum;GO:0005789|endoplasmic reticulum membrane;GO:0005794|Golgi apparatus;GO:0005811|lipid droplet;","GO:0003674|molecular_function;GO:0003824|catalytic activity;GO:0016829|lyase activity;GO:0043621|protein self-association;GO:0046872|metal ion binding;GO:0051539|4 iron, 4 sulfur cluster binding;","K15045","RSAD2; radical S-adenosyl methionine domain-containing protein 2"]
["ENSRNOG00000001189",1765,35.5005376908823,148.498749160961,869,17.2484264872447,72.1501679961449,2.05818992921673,1.04137611988782,{"v":3.77579135814811e-72,"d":"3.78E-72"},{"v":2.65763888791966E-70,"d":"2.66E-70"},"up","yes","Sik1","protein_coding","chr20:9947396-9958991:-","gi|148747268|ref|NP_067725.2|",3568,0,"serine/threonine-protein kinase SIK1 [Rattus norvegicus]","gi|6492127|gb|AF106937.1|AF106937",3304,0,"Rattus norvegicus protein kinase KID2 (Kid2) mRNA, complete cds","Q9R1U5",1379,0,"Serine/threonine-protein kinase SIK1",".",".",".",".","pfam00069","Pkinase","Protein kinase domain.","GO:0000122|negative regulation of transcription by RNA polymerase II;GO:0002028|regulation of sodium ion transport;GO:0006468|protein phosphorylation;GO:0007346|regulation of mitotic cell cycle;GO:0010830|regulation of myotube differentiation;GO:0010868|negative regulation of triglyceride biosynthetic process;GO:0032792|negative regulation of CREB transcription factor activity;GO:0035556|intracellular signal transduction;GO:0042149|cellular response to glucose starvation;GO:0043153|entrainment of circadian clock by photoperiod;GO:0043276|anoikis;GO:0045595|regulation of cell differentiation;GO:0045721|negative regulation of gluconeogenesis;GO:0046777|protein autophosphorylation;GO:0048511|rhythmic process;GO:0055007|cardiac muscle cell differentiation;GO:2000210|positive regulation of anoikis;","GO:0005634|nucleus;GO:0005737|cytoplasm;GO:0005829|cytosol;","GO:0000287|magnesium ion binding;GO:0004674|protein serine/threonine kinase activity;GO:0005515|protein binding;GO:0005524|ATP binding;GO:0008140|cAMP response element binding protein binding;GO:0019901|protein kinase binding;GO:0042826|histone deacetylase binding;GO:0071889|14-3-3 protein binding;","K19008","SIK1; serine/threonine-protein kinase SIK1 [EC:2.7.11.1]"]
["ENSRNOG00000064142",202,15.9880755094828,16.9953242665802,100,7.81059835605906,8.30266605249078,2.04697191951754,1.03349131152075,{"v":1.55106177003389E-9,"d":"1.55E-09"},{"v":1.02538609076994e-08,"d":"1.03E-08"},"up","yes","ENSRNOG00000064142","lncRNA","chr11:42908366-42909428:+","gi|149060312|gb|EDM11026.1|",184,{"v":2E-14,"d":"2.00E-14"},"rCG52582 [Rattus norvegicus]","gi|26081939|dbj|AK030674.1|",683,0,"Mus musculus 6 days neonate head cDNA, RIKEN full-length enriched library, clone:5430419M07 product:unclassifiable, full insert sequence",".",".",".",".",".",".",".",".","pfam15573","Imm27","Immunity protein 27. A predicted immunity protein with an alpha+beta fold and a conserved KxGDxxK motif. Proteins containing this domain are present in heterogeneous polyimmunity loci in polymorphic toxin systems.",".",".",".",".","."]
["ENSRNOG00000016688",437,7.10887710721053,36.7671123984929,217,3.48352384646268,18.016785333905,2.04071435148325,1.0290742555998,{"v":8.65724897117235e-19,"d":"8.66E-19"},{"v":1.22049786306441E-17,"d":"1.22E-17"},"up","yes","Ston1","protein_coding","chr6:5843185-5892449:-","gi|281427176|ref|NP_891999.2|",3555,0,"stonin-1 [Rattus norvegicus]","gi|672055393|ref|XM_008764479.1|",2745,0,"PREDICTED: Rattus norvegicus stonin 1 (Ston1), transcript variant X1, mRNA","Q8CDJ8",1213,0,"Stonin-1",".",".",".",".","pfam00928","Adap_comp_sub","Adaptor complexes medium subunit family. This family also contains members which are coatomer subunits.","GO:0006897|endocytosis;GO:0006929|substrate-dependent cell migration;GO:0016192|vesicle-mediated transport;GO:0030100|regulation of endocytosis;GO:0048008|platelet-derived growth factor receptor signaling pathway;GO:0048041|focal adhesion assembly;GO:0048488|synaptic vesicle endocytosis;GO:0097178|ruffle assembly;GO:0120181|focal adhesion disassembly;","GO:0005905|clathrin-coated pit;GO:0008021|synaptic vesicle;GO:0030136|clathrin-coated vesicle;GO:0031252|cell leading edge;GO:0031410|cytoplasmic vesicle;GO:0042995|cell projection;","GO:0035615|clathrin adaptor activity;","K20067","STON1_2; stonin-1/2"]
["ENSRNOG00000069630",445,13.2391069829082,37.4401945476644,221,6.48829277793657,18.3488919760046,2.04046078622218,1.02889498500601,{"v":4.23750626481549E-19,"d":"4.24E-19"},{"v":6.11820063946315e-18,"d":"6.12E-18"},"up","yes","Rsl1d1","protein_coding","chr10:4397821-4439593:+","gi|672066617|ref|XP_008765724.1|",1973,0,"PREDICTED: ribosomal L1 domain-containing protein 1 [Rattus norvegicus]","gi|672066616|ref|XM_008767502.1|",1960,0,"PREDICTED: Rattus norvegicus ribosomal L1 domain containing 1 (Rsl1d1), mRNA","Q8BVY0",638,0,"Ribosomal L1 domain-containing protein 1",".",".",".",".","pfam00687","Ribosomal_L1","Ribosomal protein L1p/L10e family. This family includes prokaryotic L1 and eukaryotic L10.",".",".",".",".","."]
["ENSRNOG00000017484",207,4.96606803815581,17.4160006098124,103,2.43847905162974,8.5517460340655,2.03654324396872,1.02612244885979,{"v":1.22134564926288e-09,"d":"1.22E-09"},{"v":8.158668539262e-09,"d":"8.16E-09"},"up","yes","Gja5","protein_coding","chr2:184564475-184621952:+","gi|9506725|ref|NP_062153.1|",1836,0,"gap junction alpha-5 protein [Rattus norvegicus]","gi|672043500|ref|XM_008761328.1|",3027,0,"PREDICTED: Rattus norvegicus gap junction protein, alpha 5 (Gja5), transcript variant X1, mRNA","P28234",711,0,"Gap junction alpha-5 protein",".",".",".",".","pfam00029","Connexin","Connexin.","GO:0001501|skeletal system development;GO:0001525|angiogenesis;GO:0001568|blood vessel development;GO:0003071|renal system process involved in regulation of systemic arterial blood pressure;GO:0003073|regulation of systemic arterial blood pressure;GO:0003105|negative regulation of glomerular filtration;GO:0003151|outflow tract morphogenesis;GO:0003158|endothelium development;GO:0003161|cardiac conduction system development;GO:0003174|mitral valve development;GO:0003193|pulmonary valve formation;GO:0003281|ventricular septum development;GO:0003283|atrial septum development;GO:0003284|septum primum development;GO:0003294|atrial ventricular junction remodeling;GO:0006813|potassium ion transport;GO:0007267|cell-cell signaling;GO:0007507|heart development;GO:0010643|cell communication by chemical coupling;GO:0010644|cell communication by electrical coupling;GO:0010649|regulation of cell communication by electrical coupling;GO:0010652|positive regulation of cell communication by chemical coupling;GO:0016264|gap junction assembly;GO:0030326|embryonic limb morphogenesis;GO:0035050|embryonic heart tube development;GO:0035922|foramen ovale closure;GO:0036120|cellular response to platelet-derived growth factor stimulus;GO:0042311|vasodilation;GO:0045776|negative regulation of blood pressure;GO:0045907|positive regulation of vasoconstriction;GO:0048844|artery morphogenesis;GO:0055085|transmembrane transport;GO:0055117|regulation of cardiac muscle contraction;GO:0060307|regulation of ventricular cardiac muscle cell membrane repolarization;GO:0060371|regulation of atrial cardiac muscle cell membrane depolarization;GO:0060373|regulation of ventricular cardiac muscle cell membrane depolarization;GO:0060412|ventricular septum morphogenesis;GO:0060413|atrial septum morphogenesis;GO:0061337|cardiac conduction;GO:0086005|ventricular cardiac muscle cell action potential;GO:0086015|SA node cell action potential;GO:0086044|atrial cardiac muscle cell to AV node cell communication by electrical coupling;GO:0086053|AV node cell to bundle of His cell communication by electrical coupling;GO:0086054|bundle of His cell to Purkinje myocyte communication by electrical coupling;GO:0086064|cell communication by electrical coupling involved in cardiac conduction;GO:0086065|cell communication involved in cardiac conduction;GO:0086067|AV node cell to bundle of His cell communication;GO:0086091|regulation of heart rate by cardiac conduction;GO:0097746|regulation of blood vessel diameter;GO:0098904|regulation of AV node cell action potential;GO:0098905|regulation of bundle of His cell action potential;GO:0098906|regulation of Purkinje myocyte action potential;GO:0098910|regulation of atrial cardiac muscle cell action potential;GO:1900133|regulation of renin secretion into blood stream;GO:1900825|regulation of membrane depolarization during cardiac muscle cell action potential;GO:1990029|vasomotion;","GO:0005887|integral component of plasma membrane;GO:0005921|gap junction;GO:0005922|connexin complex;GO:0014704|intercalated disc;GO:0042995|cell projection;","GO:0005243|gap junction channel activity;GO:0055077|gap junction hemi-channel activity;GO:0071253|connexin binding;GO:0086075|gap junction channel activity involved in cardiac conduction electrical coupling;GO:0086076|gap junction channel activity involved in atrial cardiac muscle cell-AV node cell electrical coupling;GO:0086077|gap junction channel activity involved in AV node cell-bundle of His cell electrical coupling;GO:0086078|gap junction channel activity involved in bundle of His cell-Purkinje myocyte electrical coupling;GO:0097718|disordered domain specific binding;","K07614","GJA5, CX40; gap junction alpha-5 protein"]
["ENSRNOG00000002436",432,12.6378428564884,36.3464360552607,216,6.2356601785049,17.93375867338,2.02670487080945,1.01913601854368,{"v":2.5363073185487e-18,"d":"2.54E-18"},{"v":3.42922125871214e-17,"d":"3.43E-17"},"up","yes","Mmd","protein_coding","chr10:75073365-75101528:+","gi|56090321|ref|NP_001007674.1|",1182,{"v":3E-152,"d":"3.00E-152"},"monocyte to macrophage differentiation factor [Rattus norvegicus]","gi|672068647|ref|XM_006247127.2|",1931,0,"PREDICTED: Rattus norvegicus monocyte to macrophage differentiation-associated (Mmd), transcript variant X2, mRNA","Q719N3",459,{"v":9e-154,"d":"9.00E-154"},"Monocyte to macrophage differentiation factor","VC0040",84,{"v":6e-17,"d":"6.00E-17"},"COG1272","pfam03006","HlyIII","Haemolysin-III related. Members of this family are integral membrane proteins. This family includes a protein with hemolytic activity from Bacillus cereus. It has been proposed that YOL002c encodes a Saccharomyces cerevisiae protein that plays a key role in metabolic pathways that regulate lipid and phosphate metabolizm. In eukaryotes, members are seven-transmembrane pass molecules found to encode functional receptors with a broad range of apparent ligand specificities, including progestin and adipoQ receptors, and hence have been named PAQR proteins. The mammalian members include progesterone binding proteins. Unlike the case with GPCR receptor proteins, the evolutionary ancestry of the members of this family can be traced back to the Archaea.","GO:0006468|protein phosphorylation;GO:0019835|cytolysis;GO:0032880|regulation of protein localization;GO:0045666|positive regulation of neuron differentiation;GO:0045860|positive regulation of protein kinase activity;","GO:0005765|lysosomal membrane;GO:0005794|Golgi apparatus;GO:0016021|integral component of membrane;GO:0031902|late endosome membrane;","GO:0004672|protein kinase activity;","K11064","MMD; monocyte to macrophage differentiation protein"]
["ENSRNOG00000002309",537,21.3923481359548,45.1806392631365,269,10.5748918945076,22.3341716812002,2.02293776138415,1.01645193397247,{"v":2.66152696413211E-22,"d":"2.66E-22"},{"v":4.68337421893028e-21,"d":"4.68E-21"},"up","yes","Hlx","protein_coding","chr13:96280339-96285750:-","gi|117940019|ref|NP_001071142.1|",1806,0,"H2.0-like homeobox protein [Rattus norvegicus]","gi|117940018|ref|NM_001077674.1|",2112,0,"Rattus norvegicus H2.0-like homeobox (Hlx), mRNA","A0JPN1",700,0,"H2.0-like homeobox protein",".",".",".",".","pfam00046","Homeobox","Homeobox domain.","GO:0001889|liver development;GO:0006357|regulation of transcription by RNA polymerase II;GO:0007519|skeletal muscle tissue development;GO:0008284|positive regulation of cell proliferation;GO:0030154|cell differentiation;GO:0045627|positive regulation of T-helper 1 cell differentiation;GO:0045629|negative regulation of T-helper 2 cell differentiation;GO:0046622|positive regulation of organ growth;GO:0048484|enteric nervous system development;GO:0048513|animal organ development;GO:0048557|embryonic digestive tract morphogenesis;","GO:0005634|nucleus;","GO:0000981|DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0043565|sequence-specific DNA binding;","K09339","HLX1; homeobox protein HLX1"]
["ENSRNOG00000004120",279,19.5451623250257,23.4737399523558,140,9.67837841256211,11.623732473487,2.01946663912799,1.0139743134279,{"v":2.81209696867793E-12,"d":"2.81E-12"},{"v":2.44051606056857e-11,"d":"2.44E-11"},"up","yes","ENSRNOG00000004120","protein_coding","chrX:30739413-30740613:+","gi|157818255|ref|NP_001101725.1|",1150,{"v":1e-154,"d":"1.00E-154"},"E3 ubiquitin-protein ligase RNF138-like [Rattus norvegicus]","gi|478733056|ref|NM_001108255.2|",1073,0,"Rattus norvegicus similar to RIKEN cDNA 1700045I19 (RGD1565844), mRNA","Q32LN5",355,{"v":5e-120,"d":"5.00E-120"},"E3 ubiquitin-protein ligase RNF138",".",".",".",".","pfam13923","zf-C3HC4_2","Zinc finger, C3HC4 type (RING finger).","GO:0000724|double-strand break repair via homologous recombination;GO:0008150|biological_process;GO:0010792|DNA double-strand break processing involved in repair via single-strand annealing;GO:0016567|protein ubiquitination;","GO:0005575|cellular_component;GO:0035861|site of double-strand break;","GO:0003674|molecular_function;GO:0003697|single-stranded DNA binding;GO:0046872|metal ion binding;GO:0061630|ubiquitin protein ligase activity;","K10668","RNF138; E3 ubiquitin-protein ligase RNF138 [EC:2.3.2.27]"]
["ENSRNOG00000011923",367,25.4556006539508,30.8776435932423,185,12.6627635590337,15.3599321971079,2.0102721286137,1.00739081087058,{"v":1.58225419072598e-15,"d":"1.58E-15"},{"v":1.76941367793864E-14,"d":"1.77E-14"},"up","yes","Mgarp","protein_coding","chr2:135431283-135439612:-","gi|157818123|ref|NP_001103026.1|",744,{"v":8e-93,"d":"8.00E-93"},"protein MGARP [Rattus norvegicus]","gi|157818122|ref|NM_001109556.1|",1161,0,"Rattus norvegicus mitochondria-localized glutamic acid-rich protein (Mgarp), mRNA","Q8VI64",207,{"v":8e-62,"d":"8.00E-62"},"Protein MGARP",".",".",".",".","pfam14962","AIF-MLS","Mitochondria Localisation Sequence. This family contains a protein found in eukaryotes. Proteins in this family are typically between 240 and 613 amino acids in length. The family is found in association with pfam07992. This protein family is an N-terminal domain for the mitochondrial localisation sequence for an apoptosis-inducing factor. The protein is also known as Corneal endothelium-specific protein 1 or as Ovary-specific acidic protein. It is thought to be important for membrane function and is expressed in the ovary and corneal endothelium.","GO:0006626|protein targeting to mitochondrion;GO:0008089|anterograde axonal transport;GO:0008090|retrograde axonal transport;GO:0010822|positive regulation of mitochondrion organization;GO:0019896|axonal transport of mitochondrion;GO:0071383|cellular response to steroid hormone stimulus;GO:0071456|cellular response to hypoxia;GO:0097211|cellular response to gonadotropin-releasing hormone;","GO:0005739|mitochondrion;GO:0031307|integral component of mitochondrial outer membrane;GO:1904115|axon cytoplasm;",".",".","."]
["ENSRNOG00000026592",208,9.6632445491214,17.5001358784588,105,4.813804171792,8.71779935511532,2.00740291965888,1.00533021901865,{"v":2.09609918460762e-09,"d":"2.10E-09"},{"v":1.35574185458996E-8,"d":"1.36E-08"},"up","yes","Rhbdl2","protein_coding","chr5:136037305-136081969:+","gi|564352686|ref|XP_006238864.1|",1392,0,"PREDICTED: rhomboid-related protein 2 isoform X1 [Rattus norvegicus]","gi|672053654|ref|XM_006238802.2|",1237,0,"PREDICTED: Rattus norvegicus rhomboid, veinlet-like 2 (Drosophila) (Rhbdl2), transcript variant X1, mRNA","A2AGA4",528,0,"Rhomboid-related protein 2","MT0119",51.2,{"v":4e-06,"d":"4.00E-06"},"COG0705","pfam01694","Rhomboid","Rhomboid family. This family contains integral membrane proteins that are related to Drosophila rhomboid protein. Members of this family are found in bacteria and eukaryotes.   Rhomboid promotes the cleavage of the membrane-anchored TGF-alpha-like growth factor Spitz, allowing it to activate the Drosophila EGF receptor. Analysis has shown that Rhomboid-1 is an intramembrane serine protease.4] (EC:3.4.21.105). Parasite-encoded rhomboid enzymes are also important for invasion of host cells by Toxoplasma and the malaria parasite.","GO:0006508|proteolysis;","GO:0005886|plasma membrane;GO:0016021|integral component of membrane;","GO:0004252|serine-type endopeptidase activity;","K02857","RHBDL1_2_3; rhomboid-related protein 1/2/3 [EC:3.4.21.105]"]
["ENSRNOG00000025527",181,1.68493954691359,15.228483625005,367,3.37140787924775,30.4707844126411,0.499773271957099,-1.00065434721632,{"v":3.43740394367916E-15,"d":"3.44E-15"},{"v":3.81282318071877e-14,"d":"3.81E-14"},"down","yes","Mtcl1","protein_coding","chr9:106321098-106442203:-","gi|569001477|ref|XP_006524915.1|",8051,0,"PREDICTED: microtubule cross-linking factor 1 isoform X4 [Mus musculus]","gi|672066369|ref|XM_006245631.2|",5756,0,"PREDICTED: Rattus norvegicus microtubule crosslinking factor 1 (Mtcl1), transcript variant X10, mRNA","Q3UHU5",3006,0,"Microtubule cross-linking factor 1",".",".",".",".","pfam14818","DUF4482","Domain of unknown function (DUF4482). This family is found in eukaryotes, and is approximately 140 amino acids in length. The family is found in association with pfam11365.","GO:0001578|microtubule bundle formation;GO:0010506|regulation of autophagy;GO:0045197|establishment or maintenance of epithelial cell apical/basal polarity;GO:0090314|positive regulation of protein targeting to membrane;","GO:0000922|spindle pole;GO:0005615|extracellular space;GO:0005856|cytoskeleton;GO:0016327|apicolateral plasma membrane;GO:0016328|lateral plasma membrane;GO:0030496|midbody;GO:0097427|microtubule bundle;","GO:0008017|microtubule binding;GO:0042803|protein homodimerization activity;",".","."]
["ENSRNOG00000000196",612,17.966079697006,51.4907844116193,1241,35.9511813368494,103.03608571141,0.499735447596851,-1.00076353889402,{"v":1.60161180047611E-47,"d":"1.60E-47"},{"v":7.1978790840247e-46,"d":"7.20E-46"},"down","yes","Cyp19a1","protein_coding","chr8:54553165-54580758:-","gi|281182626|ref|NP_058781.2|",2553,0,"aromatase [Rattus norvegicus]","gi|281182625|ref|NM_017085.2|",2525,0,"Rattus norvegicus cytochrome P450, family 19, subfamily a, polypeptide 1 (Cyp19a1), mRNA","P22443",963,0,"Aromatase","VNG0422G",97.1,{"v":1e-20,"d":"1.00E-20"},"COG2124","pfam00067","p450","Cytochrome P450. Cytochrome P450s are haem-thiolate proteins involved in the oxidative degradation of various compounds. They are particularly well known for their role in the degradation of environmental toxins and mutagens. They can be divided into 4 classes, according to the method by which electrons from NAD(P)H are delivered to the catalytic site. Sequence conservation is relatively low within the family - there are only 3 absolutely conserved residues - but their general topography and structural fold are highly conserved. The conserved core is composed of a coil termed the 'meander', a four-helix bundle, helices J and K, and two sets of beta-sheets. These constitute the haem-binding loop (with an absolutely conserved cysteine that serves as the 5th ligand for the haem iron), the proton-transfer groove and the absolutely conserved EXXR motif in helix K. While prokaryotic P450s are soluble proteins, most eukaryotic P450s are associated with microsomal membranes. their general enzymatic function is to catalyse regiospecific and stereospecific oxidation of non-activated hydrocarbons at physiological temperatures.","GO:0001553|luteinization;GO:0002677|negative regulation of chronic inflammatory response;GO:0006703|estrogen biosynthetic process;GO:0006710|androgen catabolic process;GO:0008206|bile acid metabolic process;GO:0008207|C21-steroid hormone metabolic process;GO:0008209|androgen metabolic process;GO:0008584|male gonad development;GO:0008585|female gonad development;GO:0009410|response to xenobiotic stimulus;GO:0009635|response to herbicide;GO:0010038|response to metal ion;GO:0010164|response to cesium ion;GO:0010212|response to ionizing radiation;GO:0010760|negative regulation of macrophage chemotaxis;GO:0014070|response to organic cyclic compound;GO:0018879|biphenyl metabolic process;GO:0018894|dibenzo-p-dioxin metabolic process;GO:0018963|phthalate metabolic process;GO:0021766|hippocampus development;GO:0021854|hypothalamus development;GO:0030186|melatonin metabolic process;GO:0030325|adrenal gland development;GO:0030540|female genitalia development;GO:0030851|granulocyte differentiation;GO:0030879|mammary gland development;GO:0032355|response to estradiol;GO:0033574|response to testosterone;GO:0043278|response to morphine;GO:0043627|response to estrogen;GO:0044344|cellular response to fibroblast growth factor stimulus;GO:0045779|negative regulation of bone resorption;GO:0050803|regulation of synapse structure or activity;GO:0060065|uterus development;GO:0060348|bone development;GO:0060736|prostate gland growth;GO:0061370|testosterone biosynthetic process;GO:0071333|cellular response to glucose stimulus;GO:0071371|cellular response to gonadotropin stimulus;GO:0071372|cellular response to follicle-stimulating hormone stimulus;GO:0071464|cellular response to hydrostatic pressure;GO:0097720|calcineurin-mediated signaling;GO:2000866|positive regulation of estradiol secretion;","GO:0005737|cytoplasm;GO:0005783|endoplasmic reticulum;GO:0005829|cytosol;GO:0008021|synaptic vesicle;GO:0016020|membrane;GO:0043025|neuronal cell body;GO:0043195|terminal bouton;GO:0043197|dendritic spine;GO:0043679|axon terminus;GO:0045202|synapse;","GO:0005506|iron ion binding;GO:0016712|oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen;GO:0020037|heme binding;GO:0070330|aromatase activity;","K07434","CYP19A; aromatase [EC:1.14.14.14]"]
["ENSRNOG00000009334",157,8.52208850160682,13.2092371774905,319,17.0874223919003,26.4855047074456,0.498734584196056,-1.00365584632956,{"v":1.85107332698333E-13,"d":"1.85E-13"},{"v":1.7916543218111E-12,"d":"1.79E-12"},"down","yes","Knstrn","protein_coding","chr3:105800954-105820715:+","gi|564342368|ref|XP_006234820.1|",948,{"v":3E-122,"d":"3.00E-122"},"PREDICTED: small kinetochore-associated protein isoform X2 [Rattus norvegicus]","gi|298915381|emb|FQ226275.1|",1448,0,"Rattus norvegicus TL0AEA2YL18 mRNA sequence","Q6AXN6",368,{"v":3E-122,"d":"3.00E-122"},"Small kinetochore-associated protein",".",".",".",".","pfam12718","Tropomyosin_1","Tropomyosin like. This family is a set of eukaryotic tropomyosins. Within the yeast Tmp1 and Tmp2, biochemical and sequence analyses indicate that Tpm2p spans four actin monomers along a filament, whereas Tpmlp spans five. Despite its shorter length, Tpm2p can compete with Tpm1p for binding to F-actin. Over-expression of Tpm2p in vivo alters the axial budding of haploids to a bipolar pattern, and this can be partially suppressed by co-over-expression of Tpm1p. This suggests distinct functions for the two tropomyosins, and indicates that the ratio between them is important for correct morphogenesis. The family also contains higher eukaryote Tmp3 members.","GO:0000070|mitotic sister chromatid segregation;GO:0000226|microtubule cytoskeleton organization;GO:0007051|spindle organization;GO:0007059|chromosome segregation;GO:0016477|cell migration;GO:0051301|cell division;GO:0051988|regulation of attachment of spindle microtubules to kinetochore;GO:0071364|cellular response to epidermal growth factor stimulus;","GO:0000776|kinetochore;GO:0000922|spindle pole;GO:0001726|ruffle;GO:0005634|nucleus;GO:0005737|cytoplasm;GO:0005886|plasma membrane;GO:0034451|centriolar satellite;GO:0035371|microtubule plus-end;GO:0072686|mitotic spindle;","GO:0042803|protein homodimerization activity;GO:0051010|microtubule plus-end binding;",".","."]
["ENSRNOG00000004540",318,28.1928508214614,26.7550154295669,647,56.6051099679824,53.7182493596153,0.498061938885167,-1.00560292816447,{"v":8.87669937450338e-26,"d":"8.88E-26"},{"v":1.87577265379535E-24,"d":"1.88E-24"},"down","yes","Clec3b","protein_coding","chr8:122810149-122815835:+","gi|392342149|ref|XP_003754515.1|",962,{"v":3e-128,"d":"3.00E-128"},"PREDICTED: tetranectin [Rattus norvegicus]","gi|672023508|ref|XM_003754467.3|",949,0,"PREDICTED: Rattus norvegicus tetranectin-like (LOC100912012), mRNA","P43025",359,{"v":1e-123,"d":"1.00E-123"},"Tetranectin",".",".",".",".","pfam00059","Lectin_C","Lectin C-type domain. This family includes both long and short form C-type","GO:0001501|skeletal system development;GO:0001503|ossification;GO:0010756|positive regulation of plasminogen activation;GO:0030282|bone mineralization;GO:0071310|cellular response to organic substance;GO:0071560|cellular response to transforming growth factor beta stimulus;","GO:0001652|granular component;GO:0005615|extracellular space;GO:0005737|cytoplasm;","GO:0005509|calcium ion binding;GO:0008201|heparin binding;GO:0030246|carbohydrate binding;GO:0036143|kringle domain binding;","K17520","CLEC3B; C-type lectin domain family 3 member B"]
["ENSRNOG00000047697",305,10.989831664738,25.6612569371632,623,22.1522952920846,51.7256095070175,0.496103519740676,-1.01128690203007,{"v":4.23288394473541e-25,"d":"4.23E-25"},{"v":8.63953580518183E-24,"d":"8.64E-24"},"down","yes","Ggt1","protein_coding","chr20:13074700-13108442:-","gi|145280505|ref|NP_446292.2|",2936,0,"gamma-glutamyltranspeptidase 1 [Rattus norvegicus]","gi|145280504|ref|NM_053840.2|",2042,0,"Rattus norvegicus gamma-glutamyltransferase 1 (Ggt1), mRNA","P07314",1135,0,"Glutathione hydrolase 1 proenzyme","SPAC664.09",372,{"v":4e-117,"d":"4.00E-117"},"COG0405","pfam01019","G_glu_transpept","Gamma-glutamyltranspeptidase.","GO:0002682|regulation of immune system process;GO:0006412|translation;GO:0006508|proteolysis;GO:0006520|cellular amino acid metabolic process;GO:0006536|glutamate metabolic process;GO:0006631|fatty acid metabolic process;GO:0006691|leukotriene metabolic process;GO:0006750|glutathione biosynthetic process;GO:0006751|glutathione catabolic process;GO:0007283|spermatogenesis;GO:0007568|aging;GO:0019344|cysteine biosynthetic process;GO:0031179|peptide modification;GO:0031638|zymogen activation;GO:0032355|response to estradiol;GO:0032496|response to lipopolysaccharide;GO:0034599|cellular response to oxidative stress;GO:0034612|response to tumor necrosis factor;GO:0050727|regulation of inflammatory response;GO:0061017|hepatoblast differentiation;GO:0070365|hepatocyte differentiation;GO:0097305|response to alcohol;GO:0097421|liver regeneration;GO:1901750|leukotriene D4 biosynthetic process;","GO:0005615|extracellular space;GO:0005886|plasma membrane;GO:0005887|integral component of plasma membrane;GO:0016020|membrane;GO:0031982|vesicle;","GO:0000048|peptidyltransferase activity;GO:0002951|leukotriene-C(4) hydrolase;GO:0016746|transferase activity, transferring acyl groups;GO:0016755|transferase activity, transferring amino-acyl groups;GO:0036374|glutathione hydrolase activity;GO:0102953|hypoglycin A gamma-glutamyl transpeptidase activity;GO:0103068|leukotriene C4 gamma-glutamyl transferase activity;","K18592","GGT1_5, CD224; gamma-glutamyltranspeptidase / glutathione hydrolase / leukotriene-C4 hydrolase [EC:2.3.2.2 3.4.19.13 3.4.19.14]"]
["ENSRNOG00000000655",734,4.40322903290443,61.7552871864846,1511,8.94497569006315,125.453284053135,0.492257238641343,-1.02251567377793,{"v":1.75897615647351E-59,"d":"1.76E-59"},{"v":9.96322958712655e-58,"d":"9.96E-58"},"down","yes","Ptprc","protein_coding","chr13:49596193-49708692:-","gi|56559|emb|CAA68272.1|",5958,0,"unnamed protein product [Rattus norvegicus]","gi|205146|gb|M18349.1|RATLCAG1",8442,0,"Rat leukocyte common antigen (L-CA) gene, exons 1 through 5","P04157",2296,0,"Receptor-type tyrosine-protein phosphatase C","SPAC19D5.01",135,{"v":8e-31,"d":"8.00E-31"},"COG5599","pfam00102","Y_phosphatase","Protein-tyrosine phosphatase.","GO:0001779|natural killer cell differentiation;GO:0001915|negative regulation of T cell mediated cytotoxicity;GO:0001916|positive regulation of T cell mediated cytotoxicity;GO:0001960|negative regulation of cytokine-mediated signaling pathway;GO:0002244|hematopoietic progenitor cell differentiation;GO:0002639|positive regulation of immunoglobulin production;GO:0002711|positive regulation of T cell mediated immunity;GO:0002923|regulation of humoral immune response mediated by circulating immunoglobulin;GO:0002925|positive regulation of humoral immune response mediated by circulating immunoglobulin;GO:0006469|negative regulation of protein kinase activity;GO:0006470|protein dephosphorylation;GO:0006933|negative regulation of cell adhesion involved in substrate-bound cell migration;GO:0007159|leukocyte cell-cell adhesion;GO:0010332|response to gamma radiation;GO:0010468|regulation of gene expression;GO:0016311|dephosphorylation;GO:0030183|B cell differentiation;GO:0030217|T cell differentiation;GO:0030890|positive regulation of B cell proliferation;GO:0031668|cellular response to extracellular stimulus;GO:0031953|negative regulation of protein autophosphorylation;GO:0032677|regulation of interleukin-8 production;GO:0032703|negative regulation of interleukin-2 production;GO:0032743|positive regulation of interleukin-2 production;GO:0032760|positive regulation of tumor necrosis factor production;GO:0034113|heterotypic cell-cell adhesion;GO:0035335|peptidyl-tyrosine dephosphorylation;GO:0035584|calcium-mediated signaling using intracellular calcium source;GO:0042098|T cell proliferation;GO:0042100|B cell proliferation;GO:0042102|positive regulation of T cell proliferation;GO:0043406|positive regulation of MAP kinase activity;GO:0043410|positive regulation of MAPK cascade;GO:0044770|cell cycle phase transition;GO:0044855|plasma membrane raft distribution;GO:0045059|positive thymic T cell selection;GO:0045060|negative thymic T cell selection;GO:0045582|positive regulation of T cell differentiation;GO:0045588|positive regulation of gamma-delta T cell differentiation;GO:0046425|regulation of JAK-STAT cascade;GO:0046641|positive regulation of alpha-beta T cell proliferation;GO:0048304|positive regulation of isotype switching to IgG isotypes;GO:0048539|bone marrow development;GO:0048864|stem cell development;GO:0050731|positive regulation of peptidyl-tyrosine phosphorylation;GO:0050732|negative regulation of peptidyl-tyrosine phosphorylation;GO:0050764|regulation of phagocytosis;GO:0050852|T cell receptor signaling pathway;GO:0050853|B cell receptor signaling pathway;GO:0050857|positive regulation of antigen receptor-mediated signaling pathway;GO:0051209|release of sequestered calcium ion into cytosol;GO:0051607|defense response to virus;GO:0051726|regulation of cell cycle;GO:0061097|regulation of protein tyrosine kinase activity;GO:0061099|negative regulation of protein tyrosine kinase activity;GO:0070373|negative regulation of ERK1 and ERK2 cascade;GO:0070374|positive regulation of ERK1 and ERK2 cascade;GO:1903615|positive regulation of protein tyrosine phosphatase activity;GO:1905451|positive regulation of Fc-gamma receptor signaling pathway involved in phagocytosis;GO:2000473|positive regulation of hematopoietic stem cell migration;GO:2000648|positive regulation of stem cell proliferation;GO:2001236|regulation of extrinsic apoptotic signaling pathway;GO:2001238|positive regulation of extrinsic apoptotic signaling pathway;","GO:0005886|plasma membrane;GO:0005887|integral component of plasma membrane;GO:0005925|focal adhesion;GO:0009897|external side of plasma membrane;GO:0009898|cytoplasmic side of plasma membrane;GO:0009986|cell surface;GO:0016021|integral component of membrane;GO:0032059|bleb;GO:0045121|membrane raft;GO:0071944|cell periphery;GO:0098857|membrane microdomain;","GO:0004725|protein tyrosine phosphatase activity;GO:0005001|transmembrane receptor protein tyrosine phosphatase activity;GO:0005102|signaling receptor binding;GO:0005515|protein binding;GO:0008201|heparin binding;GO:0019887|protein kinase regulator activity;GO:0019901|protein kinase binding;GO:0030506|ankyrin binding;GO:0030507|spectrin binding;GO:0043395|heparan sulfate proteoglycan binding;","K06478","PTPRC, CD45; receptor-type tyrosine-protein phosphatase C [EC:3.1.3.48]"]
["ENSRNOG00000011777",180,3.89715603611905,15.1443483563586,371,7.92663176910468,30.8028910547408,0.491653472703102,-1.02428626174744,{"v":6.99848846951249e-16,"d":"7.00E-16"},{"v":8.11056472184363E-15,"d":"8.11E-15"},"down","yes","Spag5","protein_coding","chr10:63198768-63216745:+","gi|183986372|gb|AAI66408.1|",5678,0,"Sperm associated antigen 5 [Rattus norvegicus]","gi|112984401|ref|NM_001044224.1|",3799,0,"Rattus norvegicus sperm associated antigen 5 (Spag5), mRNA","Q7TME2",1783,0,"Sperm-associated antigen 5",".",".",".",".","pfam01576","Myosin_tail_1","Myosin tail. The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.","GO:0000070|mitotic sister chromatid segregation;GO:0007051|spindle organization;GO:0007059|chromosome segregation;GO:0032388|positive regulation of intracellular transport;GO:0051294|establishment of spindle orientation;GO:0051301|cell division;GO:0051988|regulation of attachment of spindle microtubules to kinetochore;GO:0071539|protein localization to centrosome;GO:0090235|regulation of metaphase plate congression;GO:1905832|positive regulation of spindle assembly;","GO:0000776|kinetochore;GO:0005737|cytoplasm;GO:0005829|cytosol;GO:0016604|nuclear body;GO:0034451|centriolar satellite;GO:0035253|ciliary rootlet;GO:0035371|microtubule plus-end;GO:0036064|ciliary basal body;GO:0072686|mitotic spindle;GO:0097431|mitotic spindle pole;","GO:0008017|microtubule binding;","K21764","SPAG5; sperm-associated antigen 5"]
["ENSRNOG00000038999",553,8.53233148019064,46.5268035614795,1140,17.3574900052072,94.6503929983949,0.491564821735801,-1.02454642027371,{"v":1.85692107880533e-45,"d":"1.86E-45"},{"v":8.11663883211177e-44,"d":"8.12E-44"},"down","yes","RT1-CE11","protein_coding","chr20:3350937-3380362:-","gi|57012420|ref|NP_001008833.1|",1581,0,"RT1 class I, locus CE10 precursor [Rattus norvegicus]","gi|46237620|emb|BX883046.1|",3470,0,"Rattus norvegicus chromosome 20, major histocompatibility complex, assembled from 40 BACs, strain Brown Norway (BN/ssNHsd), RT1n haplotype; segment 5/11","P16391",544,{"v":7e-178,"d":"7.00E-178"},"RT1 class I histocompatibility antigen, AA alpha chain",".",".",".",".","pfam00129","MHC_I","Class I Histocompatibility antigen, domains alpha 1 and 2.","GO:0001916|positive regulation of T cell mediated cytotoxicity;GO:0002476|antigen processing and presentation of endogenous peptide antigen via MHC class Ib;GO:0002486|antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent;GO:0002517|T cell tolerance induction;GO:0002657|positive regulation of tolerance induction to nonself antigen;GO:0006955|immune response;GO:0045953|negative regulation of natural killer cell mediated cytotoxicity;","GO:0005615|extracellular space;GO:0009897|external side of plasma membrane;GO:0016021|integral component of membrane;","GO:0005102|signaling receptor binding;GO:0005515|protein binding;GO:0030881|beta-2-microglobulin binding;GO:0042277|peptide binding;GO:0042605|peptide antigen binding;GO:0044877|protein-containing complex binding;","K06751","MHC1; MHC class I antigen"]
["ENSRNOG00000019556",1490,51.6103541717541,125.36155028319,3074,105.073674126622,255.223954453566,0.491182540257984,-1.02566881579756,{"v":1.16396829416611E-119,"d":"1.16E-119"},{"v":1.4103956163128e-117,"d":"1.41E-117"},"down","yes","Cd9","protein_coding","chr4:158256328-158289222:-","gi|148229054|ref|NP_444177.1|",881,{"v":3e-109,"d":"3.00E-109"},"CD9 antigen [Rattus norvegicus]","gi|298885141|emb|FQ230141.1|",675,0,"Rattus norvegicus TL0ADA45YH23 mRNA sequence","P40241",343,{"v":1e-110,"d":"1.00E-110"},"CD9 antigen",".",".",".",".","pfam00335","Tetraspannin","Tetraspanin family.","GO:0007155|cell adhesion;GO:0007338|single fertilization;GO:0007342|fusion of sperm to egg plasma membrane involved in single fertilization;GO:0007420|brain development;GO:0008285|negative regulation of cell proliferation;GO:0008347|glial cell migration;GO:0009414|response to water deprivation;GO:0014003|oligodendrocyte development;GO:0014905|myoblast fusion involved in skeletal muscle regeneration;GO:0030913|paranodal junction assembly;GO:0031623|receptor internalization;GO:0035036|sperm-egg recognition;GO:0051271|negative regulation of cellular component movement;GO:0071404|cellular response to low-density lipoprotein particle stimulus;GO:0090331|negative regulation of platelet aggregation;GO:1905521|regulation of macrophage migration;","GO:0005886|plasma membrane;GO:0005887|integral component of plasma membrane;GO:0009897|external side of plasma membrane;GO:0009986|cell surface;GO:0016020|membrane;GO:0016324|apical plasma membrane;GO:0032991|protein-containing complex;GO:0070062|extracellular exosome;","GO:0005178|integrin binding;GO:0005515|protein binding;","K06460","CD9, TSPAN29; CD9 antigen"]
["ENSRNOG00000018434",2191,22.7524529257397,184.340373604343,4530,46.4219664499916,376.110772177832,0.490122557609659,-1.02878554739969,{"v":2.89448463267659e-176,"d":"2.89E-176"},{"v":5.32837515638335E-174,"d":"5.33E-174"},"down","yes","Stab1","protein_coding","chr16:6330444-6360923:-","gi|564318591|ref|XP_006222184.1|",13802,0,"PREDICTED: stabilin-1 isoform X1 [Rattus norvegicus]","gi|672079482|ref|XM_008771053.1|",8102,0,"PREDICTED: Rattus norvegicus stabilin 1 (Stab1), transcript variant X1, mRNA","Q8R4Y4",4809,0,"Stabilin-1","sll1483",69.3,{"v":1e-11,"d":"1.00E-11"},"COG2335","pfam00193","Xlink","Extracellular link domain.","GO:0006897|endocytosis;GO:0007155|cell adhesion;GO:0007267|cell-cell signaling;GO:0016525|negative regulation of angiogenesis;GO:0042742|defense response to bacterium;","GO:0005887|integral component of plasma membrane;","GO:0005041|low-density lipoprotein particle receptor activity;GO:0005044|scavenger receptor activity;GO:0005509|calcium ion binding;GO:0005540|hyaluronic acid binding;GO:0030169|low-density lipoprotein particle binding;","K19020","STAB1; stabilin-1"]
["ENSRNOG00000015329",461,18.9479036863739,38.7863588460073,954,38.6943987009096,79.207434140762,0.48968078901633,-1.03008649703249,{"v":1.19038910199339E-38,"d":"1.19E-38"},{"v":4.22038497561911e-37,"d":"4.22E-37"},"down","yes","Kpna2","protein_coding","chr10:91933951-91946150:-","gi|399154114|ref|NP_445935.2|",2719,0,"importin subunit alpha-1 [Rattus norvegicus]","gi|399154113|ref|NM_053483.2|",1932,0,"Rattus norvegicus karyopherin subunit alpha 2 (Kpna2), transcript variant 2, mRNA","P52293",1041,0,"Importin subunit alpha-1","SPBC1604.08c",462,{"v":3e-154,"d":"3.00E-154"},"COG5064","pfam01749","IBB","Importin beta binding domain. This family consists of the importin alpha (karyopherin alpha), importin beta (karyopherin beta) binding domain. The domain mediates formation of the importin alpha beta complex; required for classical NLS import of proteins into the nucleus, through the nuclear pore complex and across the nuclear envelope. Also in the alignment is the NLS of importin alpha which overlaps with the IBB domain.","GO:0006606|protein import into nucleus;GO:0006607|NLS-bearing protein import into nucleus;GO:0006886|intracellular protein transport;GO:0046015|regulation of transcription by glucose;GO:0075506|entry of viral genome into host nucleus through nuclear pore complex via importin;GO:0099527|postsynapse to nucleus signaling pathway;GO:1903902|positive regulation of viral life cycle;","GO:0005634|nucleus;GO:0005654|nucleoplasm;GO:0005829|cytosol;GO:0010494|cytoplasmic stress granule;GO:0043657|host cell;GO:0098892|extrinsic component of postsynaptic specialization membrane;GO:0098978|glutamatergic synapse;","GO:0008139|nuclear localization sequence binding;GO:0042826|histone deacetylase binding;GO:0061608|nuclear import signal receptor activity;","K15043","KPNA2_7; importin subunit alpha-1/8"]
["ENSRNOG00000014336",260,6.80621339392457,21.8751698480735,539,13.9238861303439,44.7513700229253,0.488815646020832,-1.03263763118037,{"v":1.20802905696153e-22,"d":"1.21E-22"},{"v":2.17775866143587e-21,"d":"2.18E-21"},"down","yes","Mcm5","protein_coding","chr19:13483066-13504389:+","gi|183986534|gb|AAI66442.1|",3713,0,"Mcm5 protein [Rattus norvegicus]","gi|672084082|ref|XM_008772283.1|",2921,0,"PREDICTED: Rattus norvegicus minichromosome maintenance complex component 5 (Mcm5), transcript variant X1, mRNA","P49718",1401,0,"DNA replication licensing factor MCM5","YLR274w",612,0,"COG1241","pfam00493","MCM","MCM2/3/5 family.","GO:0000727|double-strand break repair via break-induced replication;GO:0006270|DNA replication initiation;GO:0032508|DNA duplex unwinding;GO:0051301|cell division;","GO:0005634|nucleus;GO:0005654|nucleoplasm;GO:0005694|chromosome;GO:0042555|MCM complex;","GO:0003688|DNA replication origin binding;GO:0003697|single-stranded DNA binding;GO:0005524|ATP binding;GO:0017116|single-stranded DNA-dependent ATP-dependent DNA helicase activity;GO:0043138|3'-5' DNA helicase activity;","K02209","MCM5, CDC46; DNA replication licensing factor MCM5 [EC:5.6.2.3]"]
["ENSRNOG00000027157",161,8.90583711510607,13.5457782520763,334,18.2320214433393,27.7309046153192,0.488472281737009,-1.03365139581575,{"v":1.20970470842352E-14,"d":"1.21E-14"},{"v":1.28809107027875e-13,"d":"1.29E-13"},"down","yes","Ly6g6e","protein_coding","chr20:3744999-3750849:-","gi|564396964|ref|XP_006256133.1|",571,{"v":1e-68,"d":"1.00E-68"},"PREDICTED: lymphocyte antigen 6 complex G6E isoform X1 [Rattus norvegicus]","gi|672085752|ref|XM_006256071.2|",1049,0,"PREDICTED: Rattus norvegicus lymphocyte antigen 6 complex, locus G6E (Ly6g6e), transcript variant X2, mRNA","Q8K1T6",139,{"v":1e-37,"d":"1.00E-37"},"Lymphocyte antigen 6G6e",".",".",".",".","pfam01064","Activin_recp","Activin types I and II receptor domain. This Pfam entry consists of both TGF-beta receptor types. This is an alignment of the hydrophilic cysteine-rich ligand-binding domains, Both receptor types, (type I and II) posses a 9 amino acid cysteine box, with the the consensus CCX{4-5}CN. The type I receptors also possess 7 extracellular residues preceding the cysteine box.","GO:0002029|desensitization of G protein-coupled receptor signaling pathway;GO:0007178|transmembrane receptor protein serine/threonine kinase signaling pathway;GO:0095500|acetylcholine receptor signaling pathway;","GO:0005886|plasma membrane;GO:0045202|synapse;","GO:0004675|transmembrane receptor protein serine/threonine kinase activity;GO:0030549|acetylcholine receptor activator activity;GO:0033130|acetylcholine receptor binding;","K06846","LY6D_E_F_G6_H; lymphocyte antigen 6 complex locus protein D/E/F/G6/H"]
["ENSRNOG00000019430",642,33.3630898523857,54.0148424710124,1332,68.3085310804059,110.591511819177,0.488417615262638,-1.03381286140528,{"v":1.41672249478678e-53,"d":"1.42E-53"},{"v":7.02674787332983e-52,"d":"7.03E-52"},"down","yes","Coro1a","protein_coding","chr1:181295562-181300534:-","gi|18426834|ref|NP_569095.1|",2455,0,"coronin-1A [Rattus norvegicus]","gi|298889768|emb|FQ226941.1|",1610,0,"Rattus norvegicus TL0AEA15YO22 mRNA sequence","Q91ZN1",950,0,"Coronin-1A",".",".",".",".","pfam08954","DUF1900","Domain of unknown function (DUF1900). This domain is predominantly found in the structural protein coronin, and is duplicated in some sequences. It has no known function.","GO:0001845|phagolysosome assembly;GO:0006816|calcium ion transport;GO:0006909|phagocytosis;GO:0007015|actin filament organization;GO:0008064|regulation of actin polymerization or depolymerization;GO:0008150|biological_process;GO:0008360|regulation of cell shape;GO:0016477|cell migration;GO:0030036|actin cytoskeleton organization;GO:0030217|T cell differentiation;GO:0030335|positive regulation of cell migration;GO:0030595|leukocyte chemotaxis;GO:0030833|regulation of actin filament polymerization;GO:0031339|negative regulation of vesicle fusion;GO:0031589|cell-substrate adhesion;GO:0032796|uropod organization;GO:0032956|regulation of actin cytoskeleton organization;GO:0034097|response to cytokine;GO:0038180|nerve growth factor signaling pathway;GO:0042102|positive regulation of T cell proliferation;GO:0043029|T cell homeostasis;GO:0043320|natural killer cell degranulation;GO:0043524|negative regulation of neuron apoptotic process;GO:0048873|homeostasis of number of cells within a tissue;GO:0050870|positive regulation of T cell activation;GO:0050918|positive chemotaxis;GO:0051126|negative regulation of actin nucleation;GO:0051279|regulation of release of sequestered calcium ion into cytosol;GO:0061502|early endosome to recycling endosome transport;GO:0071353|cellular response to interleukin-4;","GO:0001772|immunological synapse;GO:0001891|phagocytic cup;GO:0005575|cellular_component;GO:0005737|cytoplasm;GO:0005769|early endosome;GO:0005829|cytosol;GO:0005884|actin filament;GO:0005886|plasma membrane;GO:0005911|cell-cell junction;GO:0015629|actin cytoskeleton;GO:0030027|lamellipodium;GO:0030424|axon;GO:0030670|phagocytic vesicle membrane;GO:0030864|cortical actin cytoskeleton;GO:0031252|cell leading edge;GO:0032426|stereocilium tip;GO:0032991|protein-containing complex;GO:0045202|synapse;GO:0045335|phagocytic vesicle;GO:0098978|glutamatergic synapse;","GO:0003674|molecular_function;GO:0003779|actin binding;GO:0003785|actin monomer binding;GO:0008022|protein C-terminus binding;GO:0008092|cytoskeletal protein binding;GO:0032036|myosin heavy chain binding;GO:0042802|identical protein binding;GO:0042803|protein homodimerization activity;GO:0043548|phosphatidylinositol 3-kinase binding;GO:0051015|actin filament binding;","K13882","CORO1A; coronin-1A"]
["ENSRNOG00000031431",174,9.71435749467817,14.63953674448,363,19.9991226081894,30.1386777705415,0.485739183913009,-1.04174622360334,{"v":5.7450098212706e-16,"d":"5.75E-16"},{"v":6.69845290862313e-15,"d":"6.70E-15"},"down","yes","Cdca8","protein_coding","chr5:137176417-137198629:-","gi|68163557|ref|NP_001020221.1|",1405,0,"borealin [Rattus norvegicus]","gi|672053831|ref|XM_008764064.1|",1507,0,"PREDICTED: Rattus norvegicus cell division cycle associated 8 (Cdca8), transcript variant X1, mRNA","Q6AXW0",545,0,"Borealin",".",".",".",".","pfam10512","Borealin","Cell division cycle-associated protein 8. The chromosomal passenger complex of Aurora B kinase, INCENP, and Survivin has essential regulatory roles at centromeres and the central spindle in mitosis. Borealin is also a member of the complex. Approximately half of Aurora B in mitotic cells is complexed with INCENP, Borealin, and Survivin. Depletion of Borealin by RNA interference delays mitotic progression and results in kinetochore-spindle mis-attachments and an increase in bipolar spindles associated with ectopic asters.","GO:0000070|mitotic sister chromatid segregation;GO:0007080|mitotic metaphase plate congression;GO:0051276|chromosome organization;GO:0051301|cell division;","GO:0000775|chromosome, centromeric region;GO:0005654|nucleoplasm;GO:0005730|nucleolus;GO:0005737|cytoplasm;GO:0010369|chromocenter;GO:0030496|midbody;GO:0032133|chromosome passenger complex;GO:0032991|protein-containing complex;GO:0045171|intercellular bridge;GO:0051233|spindle midzone;",".","K11514","CDCA8; Borealin"]
["ENSRNOG00000017672",2729,58.7225442803391,229.605148136126,5699,121.015073742058,473.168938331449,0.485249832640726,-1.04320037952377,{"v":2.74075823539088e-226,"d":"2.74E-226"},{"v":7.28777770588512e-224,"d":"7.29E-224"},"down","yes","Akr1c14","protein_coding","chr17:66156288-66173277:-","gi|157833626|pdb|1RAL|A",1515,0,"Chain A, Three-Dimensional Structure Of Rat Liver 3alpha- Hydroxysteroid(Slash)dihydrodiol Dehydrogenase: A Member Of The Aldo-Keto Reductase Superfamily","gi|767806535|ref|NM_138547.3|",1412,0,"Rattus norvegicus aldo-keto reductase family 1, member C14 (Akr1c14), mRNA","P23457",587,0,"3-alpha-hydroxysteroid dehydrogenase","slr0942",188,{"v":4E-51,"d":"4.00E-51"},"COG0656","pfam00248","Aldo_ket_red","Aldo/keto reductase family. This family includes a number of K+ ion channel beta chain regulatory domains - these are reported to have oxidoreductase activity.","GO:0006693|prostaglandin metabolic process;GO:0008202|steroid metabolic process;GO:0021766|hippocampus development;GO:0042448|progesterone metabolic process;GO:0044597|daunorubicin metabolic process;GO:0044598|doxorubicin metabolic process;","GO:0005829|cytosol;","GO:0004032|alditol:NADP+ 1-oxidoreductase activity;GO:0016229|steroid dehydrogenase activity;GO:0032052|bile acid binding;GO:0047023|androsterone dehydrogenase activity;GO:0047042|androsterone dehydrogenase (B-specific) activity;GO:0047086|ketosteroid monooxygenase activity;GO:0047834|D-threo-aldose 1-dehydrogenase activity;",".","."]
["ENSRNOG00000016752",525,14.4870501933025,44.1710160393793,1099,29.9266316552554,91.2462999168737,0.484085558314359,-1.04666603985206,{"v":2.17587607741453e-45,"d":"2.18E-45"},{"v":9.46756655392216E-44,"d":"9.47E-44"},"down","yes","Crispld2","protein_coding","chr19:48053287-48110465:+","gi|158533986|ref|NP_612527.2|",2606,0,"cysteine-rich secretory protein LCCL domain-containing 2 precursor [Rattus norvegicus]","gi|672085174|ref|XM_006255708.2|",3030,0,"PREDICTED: Rattus norvegicus cysteine-rich secretory protein LCCL domain containing 2 (Crispld2), transcript variant X1, mRNA","Q8BZQ2",940,0,"Cysteine-rich secretory protein LCCL domain-containing 2","YJL078c_1",61.2,{"v":1e-09,"d":"1.00E-09"},"COG2340","pfam03815","LCCL","LCCL domain.","GO:0030198|extracellular matrix organization;GO:0030324|lung development;GO:0060325|face morphogenesis;","GO:0005615|extracellular space;GO:0030133|transport vesicle;GO:0031012|extracellular matrix;","GO:0005539|glycosaminoglycan binding;GO:0008201|heparin binding;","K24243","CRISPLD; cysteine-rich secretory protein LCCL domain-containing"]
["ENSRNOG00000020125",227,19.1178238065477,19.0987059827411,476,39.5602506605166,39.5206904098561,0.483258409321161,-1.04913325747334,{"v":1.12996213229058E-20,"d":"1.13E-20"},{"v":1.79976709627559e-19,"d":"1.80E-19"},"down","yes","Cd79a","protein_coding","chr1:80493581-80497935:+","gi|392337482|ref|XP_003753271.1|",965,{"v":5e-128,"d":"5.00E-128"},"PREDICTED: B-cell antigen receptor complex-associated protein alpha chain isoform X1 [Rattus norvegicus]","gi|298904658|emb|FQ225076.1|",996,0,"Rattus norvegicus TL0AEA55YD17 mRNA sequence","P11911",339,{"v":5e-115,"d":"5.00E-115"},"B-cell antigen receptor complex-associated protein alpha chain",".",".",".",".","pfam07686","V-set","Immunoglobulin V-set domain. This domain is found in antibodies as well as neural protein P0 and CTL4 amongst others.","GO:0002250|adaptive immune response;GO:0030183|B cell differentiation;GO:0042100|B cell proliferation;GO:0042113|B cell activation;GO:0050853|B cell receptor signaling pathway;","GO:0005771|multivesicular body;GO:0009897|external side of plasma membrane;GO:0016021|integral component of membrane;GO:0019815|B cell receptor complex;GO:0045121|membrane raft;","GO:0004888|transmembrane signaling receptor activity;GO:0042802|identical protein binding;","K06506","CD79A, IGA; CD79A antigen"]
["ENSRNOG00000062871",306,2.31481677808035,25.7453922058096,642,4.79258371309034,53.3031160569908,0.482999758931224,-1.04990562588597,{"v":2.37622422113076e-27,"d":"2.38E-27"},{"v":5.35211428596822e-26,"d":"5.35E-26"},"down","yes","ENSRNOG00000062871","lncRNA","chr14:4458688-4487530:+","gi|1791243|gb|AAB41224.1|",471,{"v":3e-101,"d":"3.00E-101"},"ORF2 [Rattus norvegicus]","gi|1213335|gb|U48828.1|RNU48828",3612,0,"Rattus norvegicus retroviral-like ovarian specific transcript 30-1 mRNA","P11369",183,{"v":1E-97,"d":"1.00E-97"},"LINE-1 retrotransposable element ORF2 protein",".",".",".",".","pfam02263","GBP","Guanylate-binding protein, N-terminal domain. Transcription of the anti-viral guanylate-binding protein (GBP) is induced by interferon-gamma during macrophage induction. This family contains GBP1 and GPB2, both GTPases capable of binding GTP, GDP and GMP.",".",".",".",".","."]
["ENSRNOG00000008115",194,3.33788182360097,16.3222421174087,408,6.92737781066715,33.8748774941624,0.481839148207149,-1.05337648124068,{"v":4.71636890860384E-18,"d":"4.72E-18"},{"v":6.2792209860704e-17,"d":"6.28E-17"},"down","yes","Arhgap11a","protein_coding","chr3:100590865-100607559:-","gi|270483843|ref|NP_001161996.1|",2674,0,"rho GTPase-activating protein 11A [Rattus norvegicus]","gi|74205926|dbj|AK137111.1|",2253,0,"Mus musculus 12 days embryo embryonic body between diaphragm region and neck cDNA, RIKEN full-length enriched library, clone:9430083A14 product:hypothetical RhoGAP domain/Rho GTPase-activating proteins domain profile/Rho GTPase activation protein containing protein, full insert sequence","Q80Y19",863,0,"Rho GTPase-activating protein 11A",".",".",".",".","pfam00620","RhoGAP","RhoGAP domain. GTPase activator proteins towards Rho/Rac/Cdc42-like small GTPases.","GO:0007165|signal transduction;GO:0043547|positive regulation of GTPase activity;","GO:0005634|nucleus;","GO:0005096|GTPase activator activity;","K20635","ARHGAP11; Rho GTPase-activating protein 11"]
["ENSRNOG00000008736",130,5.42269951613127,10.9375849240367,274,11.2787828377911,22.7493049838247,0.480787651834359,-1.05652825138839,{"v":1.12601433179447e-12,"d":"1.13E-12"},{"v":1.0159104426506E-11,"d":"1.02E-11"},"down","yes","Slamf8","protein_coding","chr13:85047727-85057211:-","gi|564381809|ref|XP_006250346.1|",1434,0,"PREDICTED: SLAM family member 8 isoform X1 [Rattus norvegicus]","gi|672074763|ref|XM_006250284.2|",2015,0,"PREDICTED: Rattus norvegicus SLAM family member 8 (Slamf8), transcript variant X1, mRNA","Q9D3G2",476,{"v":5e-163,"d":"5.00E-163"},"SLAM family member 8",".",".",".",".","pfam13927","Ig_3","Immunoglobulin domain. This family contains immunoglobulin-like domains.","GO:0002232|leukocyte chemotaxis involved in inflammatory response;GO:0002336|B-1 B cell lineage commitment;GO:0010760|negative regulation of macrophage chemotaxis;GO:0033860|regulation of NAD(P)H oxidase activity;GO:0042742|defense response to bacterium;GO:0043549|regulation of kinase activity;GO:0045577|regulation of B cell differentiation;GO:0060266|negative regulation of respiratory burst involved in inflammatory response;GO:0071466|cellular response to xenobiotic stimulus;GO:0090027|negative regulation of monocyte chemotaxis;GO:0090383|phagosome acidification;GO:1902623|negative regulation of neutrophil migration;GO:2000509|negative regulation of dendritic cell chemotaxis;","GO:0016021|integral component of membrane;","GO:0038023|signaling receptor activity;GO:0042802|identical protein binding;","K16853","SLAMF8, CD353; SLAM family member 8"]
["ENSRNOG00000012835",130,1.56407620821346,10.9375849240367,274,3.2531538658408,22.7493049838247,0.480787651834359,-1.05652825138839,{"v":1.12601433179447e-12,"d":"1.13E-12"},{"v":1.0159104426506E-11,"d":"1.02E-11"},"down","yes","Espl1","protein_coding","chr7:133424130-133450984:+","gi|282158055|ref|NP_001164073.1|",10127,0,"separin [Rattus norvegicus]","gi|282158054|ref|NM_001170602.1|",5291,0,"Rattus norvegicus extra spindle pole bodies like 1, separase (Espl1), mRNA","P60330",3487,0,"Separin","SPCC5E4.04",144,{"v":2e-33,"d":"2.00E-33"},"COG5155","pfam03568","Peptidase_C50","Peptidase family C50.","GO:0000070|mitotic sister chromatid segregation;GO:0000212|meiotic spindle organization;GO:0000278|mitotic cell cycle;GO:0006508|proteolysis;GO:0007059|chromosome segregation;GO:0007127|meiosis I;GO:0045143|homologous chromosome segregation;GO:0051307|meiotic chromosome separation;","GO:0005634|nucleus;GO:0005737|cytoplasm;GO:0005813|centrosome;GO:0072686|mitotic spindle;","GO:0004197|cysteine-type endopeptidase activity;GO:0008233|peptidase activity;GO:0008234|cysteine-type peptidase activity;","K02365","ESP1; separase [EC:3.4.22.49]"]
["ENSRNOG00000001265",157,4.8173731500695,13.2092371774905,331,10.0225472770767,27.4818246337444,0.480653572080187,-1.05693063937191,{"v":5.21398968717146e-15,"d":"5.21E-15"},{"v":5.68463444324492e-14,"d":"5.68E-14"},"down","yes","Mad1l1","protein_coding","chr12:14320892-14630703:+","gi|157820543|ref|NP_001102857.1|",3207,0,"mitotic spindle assembly checkpoint protein MAD1 [Rattus norvegicus]","gi|157820542|ref|NM_001109387.1|",2571,0,"Rattus norvegicus MAD1 mitotic arrest deficient-like 1 (yeast) (Mad1l1), mRNA","Q9WTX8",1178,0,"Mitotic spindle assembly checkpoint protein MAD1",".",".",".",".","pfam05557","MAD","Mitotic checkpoint protein. This family consists of several eukaryotic mitotic checkpoint (Mitotic arrest deficient or MAD) proteins. The mitotic spindle checkpoint monitors proper attachment of the bipolar spindle to the kinetochores of aligned sister chromatids and causes a cell cycle arrest in prometaphase when failures occur. Multiple components of the mitotic spindle checkpoint have been identified in yeast and higher eukaryotes. In S.cerevisiae, the existence of a Mad1-dependent complex containing Mad2, Mad3, Bub3 and Cdc20 has been demonstrated.","GO:0007094|mitotic spindle assembly checkpoint;GO:0042130|negative regulation of T cell proliferation;GO:0048538|thymus development;GO:0051220|cytoplasmic sequestering of protein;GO:0051315|attachment of mitotic spindle microtubules to kinetochore;GO:0090235|regulation of metaphase plate congression;GO:1901990|regulation of mitotic cell cycle phase transition;GO:1902426|deactivation of mitotic spindle assembly checkpoint;","GO:0000776|kinetochore;GO:0000922|spindle pole;GO:0005634|nucleus;GO:0005635|nuclear envelope;GO:0005737|cytoplasm;GO:0044615|nuclear pore nuclear basket;GO:0072686|mitotic spindle;GO:0097431|mitotic spindle pole;","GO:0042802|identical protein binding;GO:0043515|kinetochore binding;","K06679","MAD1; mitotic spindle assembly checkpoint protein MAD1"]
["ENSRNOG00000067370",126,6.19944084763218,10.601043849451,266,12.9152583038745,22.0850916996254,0.480009048349607,-1.05886649345759,{"v":2.18411250914506E-12,"d":"2.18E-12"},{"v":1.91811834279272e-11,"d":"1.92E-11"},"down","yes","ENSRNOG00000067370","protein_coding","chr16:1627605-1636979:+","gi|564318467|ref|XP_006222143.1|",806,{"v":2E-100,"d":"2.00E-100"},"PREDICTED: uncharacterized protein LOC100911661 isoform X1 [Rattus norvegicus]","gi|672029006|ref|XM_006222081.2|",1071,0,"PREDICTED: Rattus norvegicus uncharacterized LOC100911661 (LOC100911661), transcript variant X1, mRNA","E9Q9R9",48.5,{"v":2e-11,"d":"2.00E-11"},"Disks large homolog 5",".",".",".",".","pfam12484","PE_PPE_C","Polymorphic PE/PPE proteins C terminal. This domain family is found in bacteria, and is approximately 90 amino acids in length. The family is found in association with pfam00823. There is a conserved SVP sequence motif. There is a single completely conserved residue W that may be functionally important. The proteins in this family are PE/PPE proteins implicated in immunostimulation and virulence.",".",".",".",".","."]
["ENSRNOG00000061895",109,3.53809578798673,9.17074428246161,231,7.39936673659479,19.1791585812537,0.478161971684481,-1.06442869809545,{"v":4.96602254394932e-11,"d":"4.97E-11"},{"v":3.83057346106812E-10,"d":"3.83E-10"},"down","yes","Ly49si1","protein_coding","chr4:163586930-163827002:-","gi|672051541|ref|XP_008761656.1|",1443,0,"PREDICTED: T-cell surface glycoprotein YE1/48-like isoform X2 [Rattus norvegicus]","gi|672051196|ref|XM_008763316.1|",934,0,"PREDICTED: Rattus norvegicus immunoreceptor Ly49si1 (Ly49si1), transcript variant X5, mRNA","P20937",326,{"v":7e-108,"d":"7.00E-108"},"T-cell surface glycoprotein YE1/48",".",".",".",".","pfam08391","Ly49","Ly49-like protein, N-terminal region. The sequences making up this family are annotated as, or are similar to, Ly49 receptors. These are type II transmembrane receptors expressed by mouse natural killer (NK) cells. They are classified as being activating (e.g.Ly49D and H) or inhibitory (e.g. Ly49A and G), depending on their effect on NK cell function. They are members of the C-type lectin receptor superfamily, and in fact in many family members this region is found immediately N-terminal to a lectin C-type domain (pfam00059).",".","GO:0016021|integral component of membrane;",".",".","."]
["ENSRNOG00000032798",562,7.54371745043036,47.2840209792975,1192,15.7893713059492,98.9677793456901,0.477771869712631,-1.06560618169755,{"v":1.73708681775452E-50,"d":"1.74E-50"},{"v":8.23184236451467e-49,"d":"8.23E-49"},"down","yes","Slco3a1","protein_coding","chr1:128106228-128387925:-","gi|149057196|gb|EDM08519.1|",3118,0,"solute carrier organic anion transporter family, member 3a1, isoform CRA_a [Rattus norvegicus]","gi|26091821|dbj|AK046945.1|",2714,0,"Mus musculus 10 days neonate cerebellum cDNA, RIKEN full-length enriched library, clone:B930006P19 product:solute carrier family 21 (organic anion transporter), member 11, full insert sequence","Q8R3L5",1201,0,"Solute carrier organic anion transporter family member 3A1",".",".",".",".","pfam03137","OATP","Organic Anion Transporter Polypeptide (OATP) family. This family consists of several eukaryotic Organic-Anion-Transporting Polypeptides (OATPs). Several have been identified mostly in human and rat. Different OATPs vary in tissue distribution and substrate specificity. Since the numbering of different OATPs in particular species was based originally on the order of discovery, similarly numbered OATPs in humans and rats did not necessarily correspond in function, tissue distribution and substrate specificity (in spite of the name, some OATPs also transport organic cations and neutral molecules). Thus, Tamai et al. initiated the current scheme of using digits for rat OATPs and letters for human ones. Prostaglandin transporter (PGT) proteins are also considered to be OATP family members. In addition, the methotrexate transporter OATK is closely related to OATPs. This family also includes several predicted proteins from Caenorhabditis elegans and Drosophila melanogaster. This similarity was not previously noted. Note: Members of this family are described (in the Swiss-Prot database) as belonging to the SLC21 family of transporters.","GO:0001934|positive regulation of protein phosphorylation;GO:0006811|ion transport;GO:0015732|prostaglandin transport;GO:0043252|sodium-independent organic anion transport;GO:0051092|positive regulation of NF-kappaB transcription factor activity;GO:0055085|transmembrane transport;","GO:0005886|plasma membrane;GO:0005887|integral component of plasma membrane;GO:0016021|integral component of membrane;","GO:0015347|sodium-independent organic anion transmembrane transporter activity;","K14353","SLCO3A; solute carrier organic anion transporter family, member 3A"]
["ENSRNOG00000018824",336,8.17508683204244,28.2694502652027,714,17.1431566266004,59.2810356147841,0.476871734308106,-1.06832682270666,{"v":4.69788561404738e-31,"d":"4.70E-31"},{"v":1.263220981332e-29,"d":"1.26E-29"},"down","yes","Slc7a5","protein_coding","chr19:49935220-49963823:-","gi|8394405|ref|NP_059049.1|",2241,0,"large neutral amino acids transporter small subunit 1 [Rattus norvegicus]","gi|8394404|ref|NM_017353.1|",3441,0,"Rattus norvegicus solute carrier family 7 member 5 (Slc7a5), mRNA","Q63016",867,0,"Large neutral amino acids transporter small subunit 1","YGR055w",100,{"v":6e-21,"d":"6.00E-21"},"COG0531","pfam13520","AA_permease_2","Amino acid permease.","GO:0003333|amino acid transmembrane transport;GO:0010629|negative regulation of gene expression;GO:0015804|neutral amino acid transport;GO:0015807|L-amino acid transport;GO:0015823|phenylalanine transport;GO:0032729|positive regulation of interferon-gamma production;GO:0032740|positive regulation of interleukin-17 production;GO:0032753|positive regulation of interleukin-4 production;GO:0042908|xenobiotic transport;GO:0070327|thyroid hormone transport;GO:0089718|amino acid import across plasma membrane;GO:0098713|leucine import across plasma membrane;GO:1903801|L-leucine import across plasma membrane;GO:1904556|L-tryptophan transmembrane transport;","GO:0005765|lysosomal membrane;GO:0005829|cytosol;GO:0005886|plasma membrane;GO:0009925|basal plasma membrane;GO:0016021|integral component of membrane;GO:0016323|basolateral plasma membrane;GO:0016324|apical plasma membrane;GO:0031528|microvillus membrane;GO:0043231|intracellular membrane-bounded organelle;GO:0098591|external side of apical plasma membrane;GO:1990184|amino acid transport complex;","GO:0015171|amino acid transmembrane transporter activity;GO:0015173|aromatic amino acid transmembrane transporter activity;GO:0015175|neutral amino acid transmembrane transporter activity;GO:0015179|L-amino acid transmembrane transporter activity;GO:0015190|L-leucine transmembrane transporter activity;GO:0015196|L-tryptophan transmembrane transporter activity;GO:0015349|thyroid hormone transmembrane transporter activity;GO:0042605|peptide antigen binding;","K13780","SLC7A5, LAT1; solute carrier family 7 (L-type amino acid transporter), member 5"]
["ENSRNOG00000028415",257,11.2035046850436,21.6227640421342,550,23.6604472998442,45.6646632886993,0.473511956180026,-1.07852724067446,{"v":1.18249121737896e-24,"d":"1.18E-24"},{"v":2.36313917952712e-23,"d":"2.36E-23"},"down","yes","Cdc20","protein_coding","chr5:131966215-131970512:-","gi|25282463|ref|NP_741990.1|",2497,0,"cell division cycle protein 20 homolog [Rattus norvegicus]","gi|25282462|ref|NM_171993.1|",1723,0,"Rattus norvegicus cell division cycle 20 (Cdc20), mRNA","Q62623",966,0,"Cell division cycle protein 20 homolog",".",".",".",".","pfam00400","WD40","WD domain, G-beta repeat.","GO:0007064|mitotic sister chromatid cohesion;GO:0008284|positive regulation of cell proliferation;GO:0016567|protein ubiquitination;GO:0031145|anaphase-promoting complex-dependent catabolic process;GO:0031915|positive regulation of synaptic plasticity;GO:0040020|regulation of meiotic nuclear division;GO:0050773|regulation of dendrite development;GO:0051301|cell division;GO:0090129|positive regulation of synapse maturation;GO:0090307|mitotic spindle assembly;GO:1904146|positive regulation of meiotic cell cycle process involved in oocyte maturation;GO:1904668|positive regulation of ubiquitin protein ligase activity;GO:1905786|positive regulation of anaphase-promoting complex-dependent catabolic process;","GO:0000922|spindle pole;GO:0005654|nucleoplasm;GO:0005680|anaphase-promoting complex;GO:0005813|centrosome;GO:0005829|cytosol;GO:0032991|protein-containing complex;GO:0048471|perinuclear region of cytoplasm;","GO:0005515|protein binding;GO:0008022|protein C-terminus binding;GO:0010997|anaphase-promoting complex binding;GO:0019899|enzyme binding;GO:0042826|histone deacetylase binding;GO:1990757|ubiquitin ligase activator activity;","K03363","CDC20; cell division cycle 20, cofactor of APC complex"]
["ENSRNOG00000063505",118,2.23200577794054,9.92796170027954,253,4.72251463866944,21.0057451128016,0.47263078014924,-1.08121450678879,{"v":3.26175741894624e-12,"d":"3.26E-12"},{"v":2.81798572432696E-11,"d":"2.82E-11"},"down","yes","Scn2b","protein_coding","chr8:45425629-45437765:+","gi|472391630|ref|XP_004415103.1|",940,{"v":5e-113,"d":"5.00E-113"},"PREDICTED: sodium channel subunit beta-2 [Odobenus rosmarus divergens]","gi|672061598|ref|XM_006242895.2|",4199,0,"PREDICTED: Rattus norvegicus sodium channel, voltage-gated, type II, beta subunit (Scn2b), transcript variant X1, mRNA","P54900",362,{"v":1e-113,"d":"1.00E-113"},"Sodium channel subunit beta-2",".",".",".",".","pfam07686","V-set","Immunoglobulin V-set domain. This domain is found in antibodies as well as neural protein P0 and CTL4 amongst others.",".",".",".",".","."]
["ENSRNOG00000028640",154,7.20624659151906,12.9568313715512,331,15.284663311315,27.4818246337444,0.471469108919419,-1.08476484756863,{"v":1.36043845848041e-15,"d":"1.36E-15"},{"v":1.52850265003167e-14,"d":"1.53E-14"},"down","yes","Siva1","protein_coding","chr6:131705323-131709690:+","gi|155369648|ref|NP_001094452.1|",816,{"v":3E-103,"d":"3.00E-103"},"apoptosis regulatory protein Siva [Rattus norvegicus]","gi|155369647|ref|NM_001100982.1|",1682,0,"Rattus norvegicus SIVA1, apoptosis-inducing factor (Siva1), mRNA","P59692",319,{"v":1e-104,"d":"1.00E-104"},"Apoptosis regulatory protein Siva",".",".",".",".","pfam05458","Siva","Cd27 binding protein (Siva). Siva binds to the CD27 cytoplasmic tail. It has a DD homology region, a box-B-like ring finger, and a zinc finger-like domain. Overexpression of Siva in various cell lines induces apoptosis, suggesting an important role for Siva in the CD27-transduced apoptotic pathway. Siva-1 binds to and inhibits BCL-X(L)-mediated protection against UV radiation-induced apoptosis. Indeed, the unique amphipathic helical region (SAH) present in Siva-1 is required for its binding to BCL-X(L) and sensitising cells to UV radiation. Natural complexes of Siva-1/BCL-X(L) are detected in HUT78 and murine thymocyte, suggesting a potential role for Siva-1 in regulating T cell homeostasis. This family contains both Siva-1 and the shorter Siva-2 lacking the sequence coded by exon 2. It has been suggested that Siva-2 could regulate the function of Siva-1.","GO:0006915|apoptotic process;GO:0006924|activation-induced cell death of T cells;GO:0032088|negative regulation of NF-kappaB transcription factor activity;GO:0046718|viral entry into host cell;GO:0097191|extrinsic apoptotic signaling pathway;GO:0097193|intrinsic apoptotic signaling pathway;GO:1901030|positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway;","GO:0005634|nucleus;GO:0005654|nucleoplasm;GO:0005737|cytoplasm;GO:0005739|mitochondrion;","GO:0001618|virus receptor activity;GO:0005164|tumor necrosis factor receptor binding;GO:0005175|CD27 receptor binding;GO:0008270|zinc ion binding;GO:0046872|metal ion binding;","K22744","SIVA1; apoptosis regulatory protein Siva"]
["ENSRNOG00000007906",112,2.15042220182586,9.42315008840092,241,4.56627685680118,20.0094251865027,0.470935571640371,-1.08639839562868,{"v":8.77959820541506e-12,"d":"8.78E-12"},{"v":7.20780420522732e-11,"d":"7.21E-11"},"down","yes","Bub1b","protein_coding","chr3:105563138-105615547:+","gi|747165376|ref|NP_612549.1|",5379,0,"mitotic checkpoint serine/threonine-protein kinase BUB1 beta [Rattus norvegicus]","gi|747165375|ref|NM_138540.1|",4382,0,"Rattus norvegicus BUB1 mitotic checkpoint serine/threonine kinase B (Bub1b), mRNA","Q9Z1S0",1787,0,"Mitotic checkpoint serine/threonine-protein kinase BUB1 beta",".",".",".",".","pfam08311","Mad3_BUB1_I","Mad3/BUB1 homology region 1. Proteins containing this domain are checkpoint proteins involved in cell division. This region has been shown to be essential for the binding of the binding of BUB1 and MAD3 to CDC20p.","GO:0006468|protein phosphorylation;GO:0007091|metaphase/anaphase transition of mitotic cell cycle;GO:0007094|mitotic spindle assembly checkpoint;GO:0008150|biological_process;GO:0051754|meiotic sister chromatid cohesion, centromeric;GO:0071459|protein localization to chromosome, centromeric region;","GO:0000776|kinetochore;GO:0000940|condensed chromosome outer kinetochore;GO:0005575|cellular_component;GO:0005737|cytoplasm;GO:0005819|spindle;GO:0005829|cytosol;GO:0048471|perinuclear region of cytoplasm;","GO:0003674|molecular_function;GO:0004672|protein kinase activity;GO:0005524|ATP binding;","K06637","BUB1B, BUBR1, MAD3L; mitotic checkpoint serine/threonine-protein kinase BUB1 beta [EC:2.7.11.1]"]
["ENSRNOG00000059507",329,4.25069155170112,27.6805033846777,708,9.02685436910852,58.7828756516347,0.470893998938072,-1.08652575780407,{"v":1.28043506030799E-31,"d":"1.28E-31"},{"v":3.52212855672316e-30,"d":"3.52E-30"},"down","yes","Lamc3","protein_coding","chr3:15165220-15226697:+","gi|157822365|ref|NP_001101300.1|",8181,0,"laminin subunit gamma-3 precursor [Rattus norvegicus]","gi|157822364|ref|NM_001107830.1|",6509,0,"Rattus norvegicus laminin subunit gamma 3 (Lamc3), mRNA","Q9R0B6",2840,0,"Laminin subunit gamma-3",".",".",".",".","pfam00055","Laminin_N","Laminin N-terminal (Domain VI).","GO:0000904|cell morphogenesis involved in differentiation;GO:0007601|visual perception;GO:0014002|astrocyte development;GO:0060041|retina development in camera-type eye;","GO:0005604|basement membrane;GO:0016020|membrane;",".","K06247","LAMC3; laminin, gamma 3"]
["ENSRNOG00000021735",138,8.91756303625828,11.6106670732082,297,18.9392612718107,24.6589181758976,0.470850626551691,-1.08665864547891,{"v":3.50152440234312e-14,"d":"3.50E-14"},{"v":3.59640121047105e-13,"d":"3.60E-13"},"down","yes","Akr1c15","protein_coding","chr17:66181493-66208061:-","gi|158138555|ref|NP_001103370.1|",1663,0,"aldo-keto reductase family 1, member C-like [Rattus norvegicus]","gi|158138554|ref|NM_001109900.1|",1302,0,"Rattus norvegicus aldo-keto reductase family 1, member C-like (Akr1cl), mRNA","P52898",485,{"v":3e-169,"d":"3.00E-169"},"Dihydrodiol dehydrogenase 3","slr0942",209,{"v":3e-62,"d":"3.00E-62"},"COG0656","pfam00248","Aldo_ket_red","Aldo/keto reductase family. This family includes a number of K+ ion channel beta chain regulatory domains - these are reported to have oxidoreductase activity.","GO:0008202|steroid metabolic process;","GO:0005737|cytoplasm;GO:0005829|cytosol;","GO:0004032|alditol:NADP+ 1-oxidoreductase activity;GO:0004033|aldo-keto reductase (NADP) activity;GO:0016229|steroid dehydrogenase activity;GO:0047086|ketosteroid monooxygenase activity;GO:0047834|D-threo-aldose 1-dehydrogenase activity;GO:0047886|farnesol dehydrogenase activity;","K04119","AKR1C3; aldo-keto reductase family 1 member C3 [EC:1.1.1.51 1.1.1.188 1.1.1.213 1.1.1.357]"]
["ENSRNOG00000008374",429,9.62250873082415,36.0940302493214,927,20.5187188234043,76.9657143065895,0.468962453925164,-1.0924556725823,{"v":3.22049568552179e-41,"d":"3.22E-41"},{"v":1.22821922327976E-39,"d":"1.23E-39"},"down","yes","Nipsnap1","protein_coding","chr14:79734209-79758098:+","gi|149047581|gb|EDM00251.1|",1411,0,"4-nitrophenylphosphatase domain and non-neuronal SNAP25-like protein homolog 1 (C. elegans), isoform CRA_e [Rattus norvegicus]","gi|209969743|ref|NM_001100730.1|",1771,0,"Rattus norvegicus nipsnap homolog 1 (C. elegans) (Nipsnap1), mRNA","O55125",530,{"v":3e-177,"d":"3.00E-177"},"Protein NipSnap homolog 1",".",".",".",".","pfam07978","NIPSNAP","NIPSNAP. Members of this family include many hypothetical proteins. It also includes members of the NIPSNAP family which have putative roles in vesicular transport. This domain is often found in duplicate.","GO:0019233|sensory perception of pain;","GO:0005739|mitochondrion;GO:0016020|membrane;GO:0097060|synaptic membrane;","GO:0042165|neurotransmitter binding;",".","."]
["ENSRNOG00000014259",209,4.91043595283588,17.5842711471053,453,10.5029537050497,37.6110772177832,0.467529048564211,-1.09687208942167,{"v":4.07867446925809e-21,"d":"4.08E-21"},{"v":6.61749958850395e-20,"d":"6.62E-20"},"down","yes","Mycl","protein_coding","chr5:135274748-135281582:+","gi|564352668|ref|XP_006238855.1|",1655,0,"PREDICTED: protein L-Myc isoform X2 [Rattus norvegicus]","gi|672053648|ref|XM_006238793.2|",3206,0,"PREDICTED: Rattus norvegicus v-myc avian myelocytomatosis viral oncogene lung carcinoma derived homolog (Mycl), transcript variant X1, mRNA","P10166",572,0,"Protein L-Myc",".",".",".",".","pfam01056","Myc_N","Myc amino-terminal region. The myc family belongs to the basic helix-loop-helix leucine zipper class of transcription factors, see pfam00010. Myc forms a heterodimer with Max, and this complex regulates cell growth through direct activation of genes involved in cell replication. Mutations in the C-terminal 20 residues of this domain cause unique changes in the induction of apoptosis, transformation, and G2 arrest.","GO:0006357|regulation of transcription by RNA polymerase II;GO:0045607|regulation of inner ear auditory receptor cell differentiation;","GO:0005654|nucleoplasm;GO:0005694|chromosome;","GO:0000978|RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0000981|DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0046983|protein dimerization activity;","K09110","LMYC, MYCL; L-myc proto-oncogene protein"]
["ENSRNOG00000019100",161,4.39370037368677,13.5457782520763,350,9.42566694249683,29.0593311837177,0.466142120286174,-1.10115821517403,{"v":9.13016192353937e-17,"d":"9.13E-17"},{"v":1.13064398360216E-15,"d":"1.13E-15"},"down","yes","Kif2c","protein_coding","chr5:130637347-130662637:-","gi|564352294|ref|XP_006238695.1|",3441,0,"PREDICTED: kinesin-like protein KIF2C isoform X2 [Rattus norvegicus]","gi|564352293|ref|XM_006238633.1|",2580,0,"PREDICTED: Rattus norvegicus kinesin family member 2C (Kif2c), transcript variant X2, mRNA","Q62909",1317,0,"Kinesin-like protein KIF2C","ECU11g0470",234,{"v":1e-65,"d":"1.00E-65"},"COG5059","pfam00225","Kinesin","Kinesin motor domain.","GO:0007018|microtubule-based movement;GO:0007019|microtubule depolymerization;GO:0007080|mitotic metaphase plate congression;GO:0030951|establishment or maintenance of microtubule cytoskeleton polarity;GO:0051301|cell division;GO:0051310|metaphase plate congression;GO:0051315|attachment of mitotic spindle microtubules to kinetochore;GO:0051983|regulation of chromosome segregation;","GO:0000775|chromosome, centromeric region;GO:0000776|kinetochore;GO:0005634|nucleus;GO:0005813|centrosome;GO:0005819|spindle;GO:0005871|kinesin complex;GO:0005874|microtubule;GO:0005881|cytoplasmic microtubule;GO:0015630|microtubule cytoskeleton;GO:0035371|microtubule plus-end;","GO:0003777|microtubule motor activity;GO:0005524|ATP binding;GO:0008017|microtubule binding;GO:0016887|ATPase activity;GO:0051010|microtubule plus-end binding;","K10393","KIF2_24, MCAK; kinesin family member 2/24"]
["ENSRNOG00000049033",216,5.80058028331642,18.1732180276303,470,12.4553241132163,39.0225304467066,0.465710906483874,-1.10249342585785,{"v":5.1247146137793e-22,"d":"5.12E-22"},{"v":8.83900933155508E-21,"d":"8.84E-21"},"down","yes","Racgap1","protein_coding","chr7:130750936-130780831:-","gi|157822001|ref|NP_001101582.1|",3186,0,"rac GTPase-activating protein 1 [Rattus norvegicus]","gi|672060075|ref|XM_006257400.2|",2836,0,"PREDICTED: Rattus norvegicus Rac GTPase-activating protein 1 (Racgap1), transcript variant X1, mRNA","Q9WVM1",1177,0,"Rac GTPase-activating protein 1",".",".",".",".","pfam00620","RhoGAP","RhoGAP domain. GTPase activator proteins towards Rho/Rac/Cdc42-like small GTPases.","GO:0000281|mitotic cytokinesis;GO:0000915|actomyosin contractile ring assembly;GO:0007283|spermatogenesis;GO:0007405|neuroblast proliferation;GO:0008272|sulfate transport;GO:0032467|positive regulation of cytokinesis;GO:0035556|intracellular signal transduction;GO:0045995|regulation of embryonic development;GO:0050790|regulation of catalytic activity;GO:0051256|mitotic spindle midzone assembly;GO:0051988|regulation of attachment of spindle microtubules to kinetochore;","GO:0005634|nucleus;GO:0005654|nucleoplasm;GO:0005819|spindle;GO:0030496|midbody;GO:0031234|extrinsic component of cytoplasmic side of plasma membrane;GO:0032154|cleavage furrow;GO:0051233|spindle midzone;GO:0072686|mitotic spindle;GO:0097149|centralspindlin complex;","GO:0005096|GTPase activator activity;GO:0005547|phosphatidylinositol-3,4,5-trisphosphate binding;GO:0008017|microtubule binding;GO:0019901|protein kinase binding;GO:0043014|alpha-tubulin binding;GO:0043015|gamma-tubulin binding;GO:0048487|beta-tubulin binding;","K16733","RACGAP1, Tum; Rac GTPase-activating protein 1"]
["ENSRNOG00000007025",168,3.48145939226635,14.1347251326013,366,7.48466939707297,30.3877577521162,0.465145380185776,-1.1042463969616,{"v":1.55714545155908e-17,"d":"1.56E-17"},{"v":2.01975973427166e-16,"d":"2.02E-16"},"down","yes","Evc2","protein_coding","chr14:73367963-73454516:-","gi|157822319|ref|NP_001099482.1|",5400,0,"limbin [Rattus norvegicus]","gi|157822318|ref|NM_001106012.1|",4060,0,"Rattus norvegicus EvC ciliary complex subunit 2 (Evc2), mRNA","Q8K1G2",1929,0,"Limbin",".",".",".",".","pfam12297","EVC2_like","Ellis van Creveld protein 2 like protein. This family of proteins is found in eukaryotes. Proteins in this family are typically between 571 and 1310 amino acids in length. There are two conserved sequence motifs: LPA and ELH. EVC2 is implicated in Ellis van Creveld chondrodysplastic dwarfism in humans. Mutations in this protein can give rise to this congenital condition. LIMBIN is a protein which shares around 80% sequence homology with EVC2 and it is implicated in a similar condition in bovine chondrodysplastic dwarfism.","GO:0007224|smoothened signaling pathway;GO:0008150|biological_process;","GO:0005575|cellular_component;GO:0005634|nucleus;GO:0005737|cytoplasm;GO:0005856|cytoskeleton;GO:0005929|cilium;GO:0016021|integral component of membrane;GO:0060170|ciliary membrane;GO:0098797|plasma membrane protein complex;","GO:0003674|molecular_function;","K19608","EVC2; ellis van creveld syndrome protein 2"]
["ENSRNOG00000006557",240,2.75401861363132,20.1924644751448,523,5.92238726875706,43.4229434545267,0.465018325998345,-1.10464052209474,{"v":2.17301497669253e-24,"d":"2.17E-24"},{"v":4.28891926524029e-23,"d":"4.29E-23"},"down","yes","Cyfip2","protein_coding","chr10:30621318-30741113:-","gi|39104558|dbj|BAC41472.2|",6724,0,"mKIAA1168 protein [Mus musculus]","gi|157819570|ref|NM_001106996.1|",5249,0,"Rattus norvegicus cytoplasmic FMR1 interacting protein 2 (Cyfip2), mRNA","Q5SQX6",2585,0,"Cytoplasmic FMR1-interacting protein 2",".",".",".",".","pfam05994","FragX_IP","Cytoplasmic Fragile-X interacting family. CYFIP1/2 (Cytoplasmic fragile X mental retardation interacting protein) like proteins for a highly conserved protein family. The function of CYFIPs is unclear, but CYFIP interaction with fragile X mental retardation interacting protein (FMRP) involves the domain of FMRP which also mediating homo- and heteromerization.","GO:0000902|cell morphogenesis;GO:0006915|apoptotic process;GO:0030833|regulation of actin filament polymerization;GO:0031175|neuron projection development;GO:0045862|positive regulation of proteolysis;GO:0051388|positive regulation of neurotrophin TRK receptor signaling pathway;GO:0097202|activation of cysteine-type endopeptidase activity;GO:0097484|dendrite extension;GO:0098609|cell-cell adhesion;","GO:0005737|cytoplasm;GO:0031209|SCAR complex;GO:0045202|synapse;GO:0048471|perinuclear region of cytoplasm;","GO:0031267|small GTPase binding;","K05749","CYFIP; cytoplasmic FMR1 interacting protein"]
["ENSRNOG00000013526",201,6.34090326131751,16.9111889979338,439,13.6665556694542,36.4487039704345,0.463972299581663,-1.10788941981275,{"v":8.04499050523974e-21,"d":"8.04E-21"},{"v":1.28996549898461e-19,"d":"1.29E-19"},"down","yes","Rassf4","protein_coding","chr4:149897543-149932411:-","gi|66730441|ref|NP_001019446.1|",1414,0,"ras association domain-containing protein 4 [Rattus norvegicus]","gi|66730440|ref|NM_001024275.1|",2412,0,"Rattus norvegicus Ras association domain family member 4 (Rassf4), mRNA","Q566C5",549,0,"Ras association domain-containing protein 4",".",".",".",".","pfam00788","RA","Ras association (RalGDS/AF-6) domain. RasGTP effectors (in cases of AF6, canoe and RalGDS); putative RasGTP effectors in other cases. Recent evidence (not yet in MEDLINE) shows that some RA domains do NOT bind RasGTP. Predicted structure similar to that determined, and that of the RasGTP-binding domain of Raf kinase.","GO:0007165|signal transduction;",".",".","K09851","RASSF2_4; Ras association domain-containing protein 2/4"]
["ENSRNOG00000020480",515,12.4797417491114,43.3296633529149,1130,27.0219258044774,93.8201263931458,0.461837614365871,-1.11454241668829,{"v":1.92669962790266E-51,"d":"1.93E-51"},{"v":9.26803845927044e-50,"d":"9.27E-50"},"down","yes","Fads1","protein_coding","chr1:206827765-206842734:+","gi|564332936|ref|XP_006231137.1|",2397,0,"PREDICTED: fatty acid desaturase 1 isoform X1 [Rattus norvegicus]","gi|672039785|ref|XM_006231075.2|",2896,0,"PREDICTED: Rattus norvegicus fatty acid desaturase 1 (Fads1), transcript variant X1, mRNA","Q920R3",862,0,"Fatty acid desaturase 1","YNL111c",62,{"v":5e-10,"d":"5.00E-10"},"COG5274","pfam00487","FA_desaturase","Fatty acid desaturase.","GO:0006629|lipid metabolic process;GO:0006636|unsaturated fatty acid biosynthetic process;GO:0007568|aging;GO:0007584|response to nutrient;GO:0009267|cellular response to starvation;GO:0009744|response to sucrose;GO:0010033|response to organic substance;GO:0014070|response to organic cyclic compound;GO:0019369|arachidonic acid metabolic process;GO:0032868|response to insulin;GO:0033189|response to vitamin A;GO:0035900|response to isolation stress;GO:0042759|long-chain fatty acid biosynthetic process;","GO:0005634|nucleus;GO:0005739|mitochondrion;GO:0005789|endoplasmic reticulum membrane;GO:0016021|integral component of membrane;GO:0043231|intracellular membrane-bounded organelle;","GO:0016213|linoleoyl-CoA desaturase activity;GO:0016491|oxidoreductase activity;GO:0016717|oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water;","K10224","FADS1; acyl-CoA (8-3)-desaturase (Delta-5 desaturase) [EC:1.14.19.44]"]
["ENSRNOG00000068953",215,5.56073862864553,18.0890827589839,472,12.0469055541827,39.1885837677565,0.461590622059356,-1.1153141812287,{"v":1.7228533108828e-22,"d":"1.72E-22"},{"v":3.07543751895117e-21,"d":"3.08E-21"},"down","yes","ENSRNOG00000068953","protein_coding","chr1:34959980-34989618:-","gi|672059154|ref|XP_008763709.1|",3178,0,"PREDICTED: MLV-related proviral Env polyprotein-like [Rattus norvegicus]","gi|291490836|gb|AC239701.6|",2620,0,"Rattus norvegicus Y Chr BAC RNAEX-260G02 (Amplicon Express Rat SHR-Akr BAC library) complete sequence","P21415",478,{"v":1e-152,"d":"1.00E-152"},"Envelope glycoprotein",".",".",".",".","pfam00429","TLV_coat","ENV polyprotein (coat polyprotein).",".",".",".",".","."]
["ENSRNOG00000021182",114,2.49581593174441,9.5914206256938,251,5.4227665344137,20.8396917917518,0.460247719665891,-1.11951752124235,{"v":9.56392397362804e-13,"d":"9.56E-13"},{"v":8.70256479498489e-12,"d":"8.70E-12"},"down","yes","Sv2a","protein_coding","chr2:183741547-183756927:+","gi|291398069|ref|XP_002715673.1|",3288,0,"PREDICTED: synaptic vesicle glycoprotein 2A [Oryctolagus cuniculus]","gi|672043352|ref|XM_006232952.2|",3843,0,"PREDICTED: Rattus norvegicus synaptic vesicle glycoprotein 2a (Sv2a), transcript variant X1, mRNA","Q7L0J3",1248,0,"Synaptic vesicle glycoprotein 2A",".",".",".",".","pfam00083","Sugar_tr","Sugar (and other) transporter.","GO:0006836|neurotransmitter transport;GO:0006874|cellular calcium ion homeostasis;GO:0014052|regulation of gamma-aminobutyric acid secretion;GO:0016082|synaptic vesicle priming;GO:0055085|transmembrane transport;","GO:0005783|endoplasmic reticulum;GO:0005911|cell-cell junction;GO:0008021|synaptic vesicle;GO:0016021|integral component of membrane;GO:0030285|integral component of synaptic vesicle membrane;GO:0030425|dendrite;GO:0030672|synaptic vesicle membrane;GO:0031594|neuromuscular junction;GO:0043005|neuron projection;GO:0043025|neuronal cell body;GO:0043195|terminal bouton;GO:0045202|synapse;GO:0048786|presynaptic active zone;GO:0098978|glutamatergic synapse;GO:0098982|GABA-ergic synapse;","GO:0005515|protein binding;GO:0019901|protein kinase binding;GO:0022857|transmembrane transporter activity;","K06258","SV2; MFS transporter, VNT family, synaptic vesicle glycoprotein 2"]
["ENSRNOG00000060703",198,7.3451425008794,16.6587831919944,437,15.9976413797992,36.2826506493847,0.459139089725711,-1.12299683087731,{"v":3.71715997418551e-21,"d":"3.72E-21"},{"v":6.0721225246787e-20,"d":"6.07E-20"},"down","yes","Troap","protein_coding","chr7:130234544-130242365:+","gi|403420638|ref|NP_001258172.1|",2993,0,"tastin [Rattus norvegicus]","gi|403420637|ref|NM_001271243.1|",2256,0,"Rattus norvegicus trophinin associated protein (Troap), mRNA","B7ZNG4",833,0,"Tastin",".",".",".",".","pfam11725","AvrE","Pathogenicity factor. This family is secreted by gram-negative Gammaproteobacteria such as Pseudomonas syringae of tomato and the fire blight plant pathogen Erwinia amylovora, amongst others. It is an essential pathogenicity factor of approximately 198 kDa. Its injection into the host-plant is dependent upon the bacterial type III or Hrp secretion system. The family is long and carries a number of predicted functional regions, including an ERMS or endoplasmic reticulum membrane retention signal at both the C- and the N-termini, a leucine-zipper motif from residues 539-560, and a nuclear localisation signal at 1358-1361. this conserved AvrE-family of effectors is among the few that are required for full virulence of many phytopathogenic pseudomonads, erwinias and pantoeas.",".",".",".",".","."]
["ENSRNOG00000021433",106,5.40177981618552,8.9183384765223,234,11.7675581846326,19.4282385628284,0.459039992106414,-1.12330824647652,{"v":4.86318311076137e-12,"d":"4.86E-12"},{"v":4.09436963440128e-11,"d":"4.09E-11"},"down","yes","Arhgef39","protein_coding","chr5:57752509-57756109:-","gi|308153222|ref|NP_001100146.2|",1618,0,"rho guanine nucleotide exchange factor 39 [Rattus norvegicus]","gi|308153221|ref|NM_001106676.2|",1621,0,"Rattus norvegicus Rho guanine nucleotide exchange factor 39 (Arhgef39), mRNA","Q66JY6",582,0,"Rho guanine nucleotide exchange factor 39",".",".",".",".","pfam00621","RhoGEF","RhoGEF domain. Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases Also called Dbl-homologous (DH) domain. It appears that pfam00169 domains invariably occur C-terminal to RhoGEF/DH domains.","GO:0030335|positive regulation of cell migration;GO:0050790|regulation of catalytic activity;","GO:0005886|plasma membrane;","GO:0005085|guanyl-nucleotide exchange factor activity;","K23798","ARHGEF39; Rho guanine nucleotide exchange factor 39"]
["ENSRNOG00000011427",130,1.7965809664975,10.9375849240367,287,3.91403606613806,23.8286515706485,0.459009813946391,-1.12340309510355,{"v":1.96911045077505e-14,"d":"1.97E-14"},{"v":2.05779209086085e-13,"d":"2.06E-13"},"down","yes","Hr","protein_coding","chr15:45626835-45646313:+","gi|564386936|ref|XP_006252345.1|",5890,0,"PREDICTED: lysine-specific demethylase hairless isoform X1 [Rattus norvegicus]","gi|560879443|ref|NM_024364.3|",5617,0,"Rattus norvegicus hair growth associated (Hr), mRNA","P97609",2241,0,"Lysine-specific demethylase hairless",".",".",".",".","pfam02373","JmjC","JmjC domain, hydroxylase. The JmjC domain belongs to the Cupin superfamily. JmjC-domain proteins may be protein hydroxylases that catalyse a novel histone modification. This is confirmed to be a hydroxylase: the human JmjC protein named Tyw5p unexpectedly acts in the biosynthesis of a hypermodified nucleoside, hydroxy-wybutosine, in tRNA-Phe by catalyzing hydroxylation.","GO:0006357|regulation of transcription by RNA polymerase II;GO:0033169|histone H3-K9 demethylation;GO:0043433|negative regulation of DNA-binding transcription factor activity;GO:0045892|negative regulation of transcription, DNA-templated;","GO:0000118|histone deacetylase complex;GO:0000785|chromatin;GO:0005654|nucleoplasm;GO:0016604|nuclear body;","GO:0003712|transcription coregulator activity;GO:0003714|transcription corepressor activity;GO:0016491|oxidoreductase activity;GO:0031490|chromatin DNA binding;GO:0032454|histone demethylase activity (H3-K9 specific);GO:0042809|vitamin D receptor binding;GO:0042826|histone deacetylase binding;GO:0044877|protein-containing complex binding;GO:0046872|metal ion binding;GO:0046966|thyroid hormone receptor binding;","K00478","HR; [histone H3]-dimethyl-L-lysine9 demethylase [EC:1.14.11.65]"]
["ENSRNOG00000009074",123,1.62791222959127,10.3486380435117,273,3.56556210843162,22.6662783232998,0.456565382984547,-1.13110661703693,{"v":6.1523075024828e-14,"d":"6.15E-14"},{"v":6.2254935555699E-13,"d":"6.23E-13"},"down","yes","AABR07017902.1","protein_coding","chr15:27109504-27665579:+","gi|60551424|gb|AAH91200.1|",766,{"v":6e-90,"d":"6.00E-90"},"RGD1359684 protein [Rattus norvegicus]","gi|218511252|gb|AC097037.8|",3033,0,"Rattus norvegicus CH230-20D8 (Children's Hospital Oakland Research Institute Rat (BN/SsNHsd/MCW) BAC library) complete sequence","P01849",223,{"v":5e-65,"d":"5.00E-65"},"T-cell receptor alpha chain C region",".",".",".",".","pfam09291","DUF1968","Domain of unknown function (DUF1968). Members of this family are found in mammalian T-cell antigen receptor, and adopt an immunoglobulin-like beta-sandwich fold, with seven strands in two beta-sheets in a Greek-key topology. Their exact function has not, as yet, been determined.",".",".",".",".","."]
["ENSRNOG00000036703",239,3.95133212939642,20.1083292064984,532,8.67954085267262,44.1701833992509,0.455246676807762,-1.13527960897676,{"v":7.97285980515684e-26,"d":"7.97E-26"},{"v":1.68850590163482e-24,"d":"1.69E-24"},"down","yes","Itgax","protein_coding","chr1:182719609-182740698:+","gi|293356227|ref|XP_574569.3|",6104,0,"PREDICTED: integrin alpha-X isoform X1 [Rattus norvegicus]","gi|672038695|ref|XM_574569.6|",4444,0,"PREDICTED: Rattus norvegicus integrin, alpha X (Itgax), transcript variant X1, mRNA","Q9QXH4",2026,0,"Integrin alpha-X",".",".",".",".","pfam08441","Integrin_alpha2","Integrin alpha. This domain is found in integrin alpha and integrin alpha precursors to the C terminus of a number of pfam01839 repeats and to the N-terminus of the pfam00357 cytoplasmic region. This region is composed of three immunoglobulin-like domains.","GO:0007229|integrin-mediated signaling pathway;GO:0008284|positive regulation of cell proliferation;GO:0010628|positive regulation of gene expression;GO:0030335|positive regulation of cell migration;GO:0031643|positive regulation of myelination;GO:0034113|heterotypic cell-cell adhesion;GO:0045766|positive regulation of angiogenesis;GO:0051607|defense response to virus;GO:1905956|positive regulation of endothelial tube morphogenesis;","GO:0008305|integrin complex;GO:0009897|external side of plasma membrane;GO:0009986|cell surface;","GO:0030971|receptor tyrosine kinase binding;GO:0046872|metal ion binding;","K06462","ITGAX, CD11c; integrin alpha X"]
["ENSRNOG00000017622",264,24.4892071914656,22.2117109226593,589,53.9169824136391,48.9027030491707,0.454202110266295,-1.13859368592832,{"v":1.53283402702705E-28,"d":"1.53E-28"},{"v":3.65002609842414e-27,"d":"3.65E-27"},"down","yes","Npm3","protein_coding","chr1:244595644-244597591:-","gi|109460217|ref|XP_577868.2|",712,{"v":5E-91,"d":"5.00E-91"},"PREDICTED: nucleoplasmin-3 [Rattus norvegicus]","gi|672014968|ref|XM_001058548.5|",907,0,"PREDICTED: Rattus norvegicus nucleophosmin/nucleoplasmin, 3 (Npm3), mRNA","Q9CPP0",270,{"v":4e-89,"d":"4.00E-89"},"Nucleoplasmin-3",".",".",".",".","pfam03066","Nucleoplasmin","Nucleoplasmin. Nucleoplasmins are also known as chromatin decondensation proteins. They bind to core histones and transfer DNA to them in a reaction that requires ATP. This is thought to play a role in the assembly of regular nucleosomal arrays.","GO:0006338|chromatin remodeling;GO:0006364|rRNA processing;GO:0009303|rRNA transcription;","GO:0005654|nucleoplasm;GO:0005730|nucleolus;GO:0005737|cytoplasm;GO:0005829|cytosol;GO:0015629|actin cytoskeleton;","GO:0003682|chromatin binding;GO:0003723|RNA binding;GO:0042393|histone binding;","K11278","NPM3; nucleophosmin 3"]
["ENSRNOG00000016544",406,5.28203480291531,34.1589190704533,909,11.670207888842,75.4712344171412,0.4526084584976,-1.14366454846525,{"v":2.02744959926833E-43,"d":"2.03E-43"},{"v":8.40165757557823e-42,"d":"8.40E-42"},"down","yes","Arhgef28","protein_coding","chr2:29263886-29560672:-","gi|672041248|ref|XP_008758898.1|",8367,0,"PREDICTED: rho guanine nucleotide exchange factor 28 isoform X1 [Rattus norvegicus]","gi|157818586|ref|NM_001108542.1|",6135,0,"Rattus norvegicus Rho guanine nucleotide exchange factor 28 (Arhgef28), mRNA","P0C6P5",3200,0,"Rho guanine nucleotide exchange factor 28",".",".",".",".","pfam00621","RhoGEF","RhoGEF domain. Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases Also called Dbl-homologous (DH) domain. It appears that pfam00169 domains invariably occur C-terminal to RhoGEF/DH domains.","GO:0000902|cell morphogenesis;GO:0021955|central nervous system neuron axonogenesis;GO:0035023|regulation of Rho protein signal transduction;GO:0035556|intracellular signal transduction;GO:0050790|regulation of catalytic activity;GO:0060052|neurofilament cytoskeleton organization;","GO:0005737|cytoplasm;GO:0005886|plasma membrane;","GO:0003723|RNA binding;GO:0005085|guanyl-nucleotide exchange factor activity;GO:0046872|metal ion binding;","K21072","ARHGEF28; A-kinase anchor protein 28"]
["ENSRNOG00000003515",876,27.3275844769294,73.7024953342786,1965,60.4921720175913,163.147387931443,0.451754062806382,-1.14639051900111,{"v":4.32610621167698e-92,"d":"4.33E-92"},{"v":3.94398058951794e-90,"d":"3.94E-90"},"down","yes","Ephx1","protein_coding","chr13:92714315-92790235:-","gi|77539442|ref|NP_001029262.1|",2115,0,"epoxide hydrolase 1 precursor [Rattus norvegicus]","gi|403420612|ref|NM_012844.3|",1408,0,"Rattus norvegicus epoxide hydrolase 1 (Ephx1), transcript variant 2, mRNA","P07687",819,0,"Epoxide hydrolase 1","CAC0719",272,{"v":2e-83,"d":"2.00E-83"},"COG0596","pfam06441","EHN","Epoxide hydrolase N terminus. This family represents the N-terminal region of the eukaryotic epoxide hydrolase protein. Epoxide hydrolases (EC:3.3.2.3) comprise a group of functionally related enzymes that catalyse the addition of water to oxirane compounds (epoxides), thereby usually generating vicinal trans-diols. EHs have been found in all types of living organisms, including mammals, invertebrates, plants, fungi and bacteria. In animals, the major interest in EH is directed towards their detoxification capacity for epoxides since they are important safeguards against the cytotoxic and genotoxic potential of oxirane derivatives that are often reactive electrophiles because of the high tension of the three-membered ring system and the strong polarization of the C--O bonds. This is of significant relevance because epoxides are frequent intermediary metabolites which arise during the biotransformation of foreign compounds. This family is often found in conjunction with pfam00561.","GO:0001889|liver development;GO:0006725|cellular aromatic compound metabolic process;GO:0009636|response to toxic substance;GO:0014070|response to organic cyclic compound;GO:0019369|arachidonic acid metabolic process;GO:0019439|aromatic compound catabolic process;GO:0034312|diol biosynthetic process;GO:0071310|cellular response to organic substance;GO:0071385|cellular response to glucocorticoid stimulus;GO:0097176|epoxide metabolic process;","GO:0005789|endoplasmic reticulum membrane;GO:0005886|plasma membrane;GO:0016020|membrane;GO:0016021|integral component of membrane;GO:0043231|intracellular membrane-bounded organelle;","GO:0004301|epoxide hydrolase activity;GO:0019899|enzyme binding;GO:0033961|cis-stilbene-oxide hydrolase activity;","K01253","EPHX1; microsomal epoxide hydrolase [EC:3.3.2.9]"]
["ENSRNOG00000048636",173,5.53647830956012,14.5554014758335,389,12.2850402982841,32.2973709441891,0.450668306748117,-1.14986209880579,{"v":1.11131901832494e-19,"d":"1.11E-19"},{"v":1.68059058729185E-18,"d":"1.68E-18"},"down","yes","Il2rb","protein_coding","chr7:110033341-110048054:-","gi|564360935|ref|XP_006242032.1|",2407,0,"PREDICTED: interleukin-2 receptor subunit beta isoform X1 [Rattus norvegicus]","gi|672059844|ref|XM_006241970.2|",2553,0,"PREDICTED: Rattus norvegicus interleukin 2 receptor, beta (Il2rb), transcript variant X1, mRNA","P26896",894,0,"Interleukin-2 receptor subunit beta",".",".",".",".","pfam00041","fn3","Fibronectin type III domain.","GO:0019221|cytokine-mediated signaling pathway;GO:0030101|natural killer cell activation;GO:0035723|interleukin-15-mediated signaling pathway;GO:0038110|interleukin-2-mediated signaling pathway;GO:0043066|negative regulation of apoptotic process;GO:0050766|positive regulation of phagocytosis;","GO:0005886|plasma membrane;GO:0009897|external side of plasma membrane;GO:0009986|cell surface;GO:0016021|integral component of membrane;","GO:0004896|cytokine receptor activity;GO:0004911|interleukin-2 receptor activity;GO:0019976|interleukin-2 binding;GO:0042010|interleukin-15 receptor activity;","K05069","IL2RB, CD122; interleukin 2 receptor beta"]
["ENSRNOG00000012436",143,6.4545833779187,12.0313434164404,323,14.3871305523311,26.8176113495452,0.4486359079346,-1.15638299937185,{"v":9.64074473770775e-17,"d":"9.64E-17"},{"v":1.1907916254577e-15,"d":"1.19E-15"},"down","yes","Adh6","protein_coding","chr2:226797303-226808892:+","gi|21070353|gb|AAM34269.1|AF508795_1",1809,0,"ADH-like protein [Rattus norvegicus]","gi|685156909|ref|NM_019286.4|",1806,0,"Rattus norvegicus alcohol dehydrogenase 1 (class I) (Adh1), mRNA","P06757",701,0,"Alcohol dehydrogenase 1","YPO1502",366,{"v":5e-120,"d":"5.00E-120"},"COG1062","pfam08240","ADH_N","Alcohol dehydrogenase GroES-like domain. This is the catalytic domain of alcohol dehydrogenases. Many of them contain an inserted zinc binding domain. This domain has a GroES-like structure.","GO:0001523|retinoid metabolic process;GO:0006068|ethanol catabolic process;GO:0006069|ethanol oxidation;GO:0008150|biological_process;GO:0031100|animal organ regeneration;GO:0032526|response to retinoic acid;GO:0032570|response to progesterone;GO:0033574|response to testosterone;GO:0042572|retinol metabolic process;GO:0042573|retinoic acid metabolic process;GO:0046186|acetaldehyde biosynthetic process;GO:0048149|behavioral response to ethanol;GO:0048545|response to steroid hormone;","GO:0005575|cellular_component;GO:0005654|nucleoplasm;GO:0005739|mitochondrion;GO:0005829|cytosol;GO:0005886|plasma membrane;","GO:0003674|molecular_function;GO:0004022|alcohol dehydrogenase (NAD) activity;GO:0004024|alcohol dehydrogenase activity, zinc-dependent;GO:0004745|retinol dehydrogenase activity;GO:0008270|zinc ion binding;GO:0016491|oxidoreductase activity;GO:0035276|ethanol binding;GO:0042802|identical protein binding;GO:0051287|NAD binding;GO:0097159|organic cyclic compound binding;","K13951","ADH1_7; alcohol dehydrogenase 1/7 [EC:1.1.1.1]K13951; K13952"]
["ENSRNOG00000013971",108,4.15482808130552,9.08660901381518,244,9.26314822500114,20.2585051680775,0.448533045179141,-1.15671381685574,{"v":5.06673753391041E-13,"d":"5.07E-13"},{"v":4.73185504944677e-12,"d":"4.73E-12"},"down","yes","Psat1","protein_coding","chr1:213196709-213218682:-","gi|61889115|ref|NP_942033.2|",1916,0,"phosphoserine aminotransferase [Rattus norvegicus]","gi|61889114|ref|NM_198738.2|",2050,0,"Rattus norvegicus phosphoserine aminotransferase 1 (Psat1), mRNA","Q99K85",726,0,"Phosphoserine aminotransferase","PA3167",360,{"v":1e-116,"d":"1.00E-116"},"COG1932","pfam00266","Aminotran_5","Aminotransferase class-V. This domain is found in amino transferases, and other enzymes including cysteine desulphurase EC:4.4.1.-.","GO:0006564|L-serine biosynthetic process;","GO:0005737|cytoplasm;GO:0005829|cytosol;","GO:0004648|O-phospho-L-serine:2-oxoglutarate aminotransferase activity;GO:0030170|pyridoxal phosphate binding;GO:0042802|identical protein binding;","K00831","serC, PSAT1; phosphoserine aminotransferase [EC:2.6.1.52]"]
["ENSRNOG00000018804",185,1.72274761478592,15.5650246995908,418,3.84118916429568,34.7051440994114,0.448493302750895,-1.15684165302089,{"v":3.2170223342899e-21,"d":"3.22E-21"},{"v":5.2912463459889e-20,"d":"5.29E-20"},"down","yes","Ripor2","protein_coding","chr17:40323867-40548092:-","gi|564391393|ref|XP_006253992.1|",5439,0,"PREDICTED: protein FAM65B isoform X2 [Rattus norvegicus]","gi|564391392|ref|XM_006253930.1|",5217,0,"PREDICTED: Rattus norvegicus family with sequence similarity 65, member B (Fam65b), transcript variant X2, mRNA","Q80U16",1979,0,"Rho family-interacting cell polarization regulator 2",".",".",".",".","pfam04065","Not3","Not1 N-terminal domain, CCR4-Not complex component.","GO:0006935|chemotaxis;GO:0007155|cell adhesion;GO:0007162|negative regulation of cell adhesion;GO:0007605|sensory perception of sound;GO:0035024|negative regulation of Rho protein signal transduction;GO:0042130|negative regulation of T cell proliferation;GO:0045184|establishment of protein localization;GO:0045663|positive regulation of myoblast differentiation;GO:0048741|skeletal muscle fiber development;GO:0051260|protein homooligomerization;GO:0051491|positive regulation of filopodium assembly;GO:0051726|regulation of cell cycle;GO:0060088|auditory receptor cell stereocilium organization;GO:0071260|cellular response to mechanical stimulus;GO:0090023|positive regulation of neutrophil chemotaxis;GO:1901673|regulation of mitotic spindle assembly;GO:1901741|positive regulation of myoblast fusion;GO:1903904|negative regulation of establishment of T cell polarity;GO:1905872|negative regulation of protein localization to cell leading edge;GO:1990869|cellular response to chemokine;GO:2000114|regulation of establishment of cell polarity;GO:2000391|positive regulation of neutrophil extravasation;GO:2000405|negative regulation of T cell migration;GO:2001107|negative regulation of Rho guanyl-nucleotide exchange factor activity;","GO:0005737|cytoplasm;GO:0005856|cytoskeleton;GO:0016324|apical plasma membrane;GO:0030175|filopodium;GO:0032420|stereocilium;GO:0060171|stereocilium membrane;","GO:0008199|ferric iron binding;GO:0042802|identical protein binding;GO:0071889|14-3-3 protein binding;","K24818","RIPOR, FAM65; Rho family-interacting cell polarization regulator"]
["ENSRNOG00000002711",131,3.405970393289,11.0217201926832,297,7.62018485040099,24.6589181758976,0.446966899117909,-1.16176010071963,{"v":1.27199473938528e-15,"d":"1.27E-15"},{"v":1.43587407116547e-14,"d":"1.44E-14"},"down","yes","Nuf2","protein_coding","chr13:81693598-81722766:-","gi|58865624|ref|NP_001012028.1|",1963,0,"kinetochore protein Nuf2 [Rattus norvegicus]","gi|58865623|ref|NM_001012028.1|",1254,0,"Rattus norvegicus NUF2, NDC80 kinetochore complex component (Nuf2), mRNA","Q6AYL9",760,0,"Kinetochore protein Nuf2",".",".",".",".","pfam03800","Nuf2","Nuf2 family. Members of this family are components of the mitotic spindle. It has been shown that Nuf2 from yeast is part of a complex called the Ndc80p complex. This complex is thought to bind to the microtubules of the spindle. An arabidopsis protein has been included in this family that has previously not been identified as a member of this family. The match is not strong, but in common with other members of this family contains coiled-coil to the C terminus of this region.","GO:0007052|mitotic spindle organization;GO:0045132|meiotic chromosome segregation;GO:0051301|cell division;GO:0051315|attachment of mitotic spindle microtubules to kinetochore;GO:0051383|kinetochore organization;","GO:0000776|kinetochore;GO:0005654|nucleoplasm;GO:0005829|cytosol;GO:0031262|Ndc80 complex;","GO:0044877|protein-containing complex binding;","K11548","NUF2, CDCA1; kinetochore protein Nuf2"]
["ENSRNOG00000011068",371,8.90053740171886,31.214184667828,844,19.9813234910242,70.0745014830222,0.445442835942125,-1.1666877935427,{"v":1.08005637575463E-41,"d":"1.08E-41"},{"v":4.16890150301487e-40,"d":"4.17E-40"},"down","yes","Papss2","protein_coding","chr1:230454426-230539331:+","gi|564333456|ref|XP_006231336.1|",3267,0,"PREDICTED: bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 2 isoform X1 [Rattus norvegicus]","gi|672040070|ref|XM_006231274.2|",3500,0,"PREDICTED: Rattus norvegicus 3'-phosphoadenosine 5'-phosphosulfate synthase 2 (Papss2), transcript variant X1, mRNA","O88428",1220,0,"Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 2","SPAC1782.11",214,{"v":6e-62,"d":"6.00E-62"},"COG0529","pfam01583","APS_kinase","Adenylylsulphate kinase. Enzyme that catalyses the phosphorylation of adenylylsulphate to 3'-phosphoadenylylsulfate. This domain contains an ATP binding P-loop motif.","GO:0000103|sulfate assimilation;GO:0007596|blood coagulation;GO:0008150|biological_process;GO:0016310|phosphorylation;GO:0050428|3'-phosphoadenosine 5'-phosphosulfate biosynthetic process;GO:0060348|bone development;","GO:0005575|cellular_component;GO:0005829|cytosol;","GO:0003674|molecular_function;GO:0004020|adenylylsulfate kinase activity;GO:0004781|sulfate adenylyltransferase (ATP) activity;GO:0005524|ATP binding;GO:0098616|selenate adenylyltransferase (ATP) activity;","K13811","PAPSS; 3'-phosphoadenosine 5'-phosphosulfate synthase [EC:2.7.7.4 2.7.1.25]"]
["ENSRNOG00000007748",316,2.72880477186431,26.586744892274,721,6.14412626895807,59.8622222384585,0.444132274047009,-1.17093868252004,{"v":4.56599351477558e-36,"d":"4.57E-36"},{"v":1.44251238978049e-34,"d":"1.44E-34"},"down","yes","Tex15","protein_coding","chr16:58598989-58658467:-","gi|564389384|ref|XP_006253280.1|",16266,0,"PREDICTED: testis-expressed sequence 15 protein isoform X1 [Rattus norvegicus]","gi|672080305|ref|XM_008771297.1|",9477,0,"PREDICTED: Rattus norvegicus testis expressed 15 (Tex15), transcript variant X3, mRNA","F8VPN2",4348,0,"Testis-expressed protein 15",".",".",".",".","pfam15326","TEX15","Testis expressed sequence 15. TEX15 is a family of eukaryotic proteins that is required for chromosomal synapsis and meiotic recombination. TEX15 regulates the loading of DNA repair proteins onto sites of double-stranded-breaks and, thus, its absence causes a failure in meiotic recombination. Two polymorphisms in the TEX15 gene could be considered the genetic risk factors for spermatogenic failure in the Chinese Han population.","GO:0006306|DNA methylation;GO:0007129|synapsis;GO:0007130|synaptonemal complex assembly;GO:0007140|male meiotic nuclear division;GO:0007283|spermatogenesis;GO:0009566|fertilization;GO:0010529|negative regulation of transposition;GO:0010569|regulation of double-strand break repair via homologous recombination;GO:0030539|male genitalia development;GO:0032880|regulation of protein localization;GO:0034502|protein localization to chromosome;GO:0048873|homeostasis of number of cells within a tissue;","GO:0005634|nucleus;GO:0005737|cytoplasm;",".","K25680","TEX15; testis-expressed protein 15"]
["ENSRNOG00000012862",152,5.12157021796491,12.7885608342584,349,11.6044471458521,28.9763045231928,0.441345473299479,-1.18001969422238,{"v":1.66995732963672E-18,"d":"1.67E-18"},{"v":2.30341820020076e-17,"d":"2.30E-17"},"down","yes","Spsb4","protein_coding","chr8:97536520-97609787:-","gi|21553087|ref|NP_660116.1|",1424,0,"SPRY domain-containing SOCS box protein 4 [Mus musculus]","gi|197927328|ref|NM_001106849.2|",2243,0,"Rattus norvegicus splA/ryanodine receptor domain and SOCS box containing 4 (Spsb4), mRNA","Q8R5B6",553,0,"SPRY domain-containing SOCS box protein 4",".",".",".",".","pfam00622","SPRY","SPRY domain. SPRY Domain is named from SPla and the RYanodine Receptor. Domain of unknown function. Distant homologues are domains in butyrophilin/marenostrin/pyrin homologues.","GO:0006511|ubiquitin-dependent protein catabolic process;GO:0016567|protein ubiquitination;GO:0035556|intracellular signal transduction;GO:0042752|regulation of circadian rhythm;GO:0043161|proteasome-mediated ubiquitin-dependent protein catabolic process;GO:1902916|positive regulation of protein polyubiquitination;","GO:0005829|cytosol;GO:0019005|SCF ubiquitin ligase complex;","GO:1990756|protein binding, bridging involved in substrate recognition for ubiquitination;","K10343","SPSB1_4, SSB1, SSB4; SPRY domain-containing SOCS box protein 1/4"]
["ENSRNOG00000068374",101,5.59424761901917,8.49766213329012,232,12.6808329438963,19.2621852417786,0.441157741275333,-1.18063349383209,{"v":8.09449488071026E-13,"d":"8.09E-13"},{"v":7.40202332403098e-12,"d":"7.40E-12"},"down","yes","Insyn1","protein_coding","chr8:58904153-58914843:+","gi|198278561|ref|NP_001107263.1|",1291,{"v":2e-173,"d":"2.00E-173"},"UPF0583 protein C15orf59 homolog [Rattus norvegicus]","gi|198278560|ref|NM_001113791.1|",1519,0,"Rattus norvegicus similar to RIKEN cDNA 6030419C18 gene (RGD1562618), mRNA",".",".",".",".",".",".",".",".","pfam15252","DUF4589","Domain of unknown function (DUF4589). This protein family is a domain of unknown function. The precise function of the protein domain remains to be elucidated. This family of proteins is found in eukaryotes and are typically between 215 and 293 amino acids in length. The protein contains two conserved sequence motifs: SSS and KST.",".",".",".",".","."]
["ENSRNOG00000010617",159,1.79539762646402,13.3775077147834,367,4.0894892514617,30.4707844126411,0.439027349398778,-1.18761727901517,{"v":1.46744542736781E-19,"d":"1.47E-19"},{"v":2.19487036900759e-18,"d":"2.19E-18"},"down","yes","Scube1","protein_coding","chr7:114759010-114880940:-","gi|564361208|ref|XP_006242154.1|",4750,0,"PREDICTED: signal peptide, CUB and EGF-like domain-containing protein 1 isoform X1 [Rattus norvegicus]","gi|672060007|ref|XM_006242092.2|",2817,0,"PREDICTED: Rattus norvegicus signal peptide, CUB domain, EGF-like 1 (Scube1), transcript variant X1, mRNA","Q6NZL8",1772,0,"Signal peptide, CUB and EGF-like domain-containing protein 1",".",".",".",".","pfam00431","CUB","CUB domain.","GO:0007165|signal transduction;GO:0045880|positive regulation of smoothened signaling pathway;","GO:0005615|extracellular space;GO:0009897|external side of plasma membrane;GO:0009986|cell surface;GO:0019897|extrinsic component of plasma membrane;","GO:0005509|calcium ion binding;GO:0042802|identical protein binding;","K24468","SCUBE1_3; signal peptide, CUB and EGF-like domain-containing protein 1/3"]
["ENSRNOG00000008534",147,3.82906640589046,12.3678844910262,342,8.79105817322553,28.3951178995184,0.435563766095014,-1.19904415150585,{"v":1.36626777269577e-18,"d":"1.37E-18"},{"v":1.89545563525762e-17,"d":"1.90E-17"},"down","yes","Dusp15","protein_coding","chr3:141408498-141418999:-","gi|348605122|ref|NP_001102068.2|",1129,{"v":3e-143,"d":"3.00E-143"},"dual specificity protein phosphatase 15 isoform 1 [Rattus norvegicus]","gi|348605121|ref|NM_001108598.2|",3130,0,"Rattus norvegicus dual specificity phosphatase 15 (Dusp15), transcript variant 1, mRNA","B4F7B7",416,{"v":4E-136,"d":"4.00E-136"},"Dual specificity protein phosphatase 15","YIR026c",59.7,{"v":2E-8,"d":"2.00E-08"},"COG2453","pfam00782","DSPc","Dual specificity phosphatase, catalytic domain. Ser/Thr and Tyr protein phosphatases. The enzyme's tertiary fold is highly similar to that of tyrosine-specific phosphatases, except for a \"recognition\" region.","GO:0000122|negative regulation of transcription by RNA polymerase II;GO:0007179|transforming growth factor beta receptor signaling pathway;GO:0016311|dephosphorylation;GO:0035335|peptidyl-tyrosine dephosphorylation;GO:0042127|regulation of cell proliferation;GO:0046330|positive regulation of JNK cascade;GO:0048713|regulation of oligodendrocyte differentiation;GO:0070374|positive regulation of ERK1 and ERK2 cascade;","GO:0005829|cytosol;GO:0005886|plasma membrane;","GO:0004725|protein tyrosine phosphatase activity;GO:0008138|protein tyrosine/serine/threonine phosphatase activity;GO:0016791|phosphatase activity;","K14165","K14165; atypical dual specificity phosphatase [EC:3.1.3.16 3.1.3.48]"]
["ENSRNOG00000012543",271,7.77648629030845,22.8006578031843,631,17.8682888101012,52.3898227912168,0.435211584777624,-1.200211135085,{"v":5.57045664429901e-33,"d":"5.57E-33"},{"v":1.60612597179805e-31,"d":"1.61E-31"},"down","yes","Mcm3","protein_coding","chr9:23219169-23237314:-","gi|558611343|ref|NP_001178734.2|",3956,0,"DNA replication licensing factor MCM3 [Rattus norvegicus]","gi|558611342|ref|NM_001191805.2|",2932,0,"Rattus norvegicus minichromosome maintenance complex component 3 (Mcm3), mRNA","P25206",1493,0,"DNA replication licensing factor MCM3","SPCC1682.02c",658,0,"COG1241","pfam00493","MCM","MCM2/3/5 family.","GO:0000727|double-strand break repair via break-induced replication;GO:0006271|DNA strand elongation involved in DNA replication;GO:0032508|DNA duplex unwinding;GO:1902975|mitotic DNA replication initiation;","GO:0005634|nucleus;GO:0005654|nucleoplasm;GO:0005694|chromosome;GO:0005737|cytoplasm;GO:0005813|centrosome;GO:0042555|MCM complex;GO:0048471|perinuclear region of cytoplasm;","GO:0003697|single-stranded DNA binding;GO:0005524|ATP binding;GO:0017116|single-stranded DNA-dependent ATP-dependent DNA helicase activity;","K02541","MCM3; DNA replication licensing factor MCM3 [EC:5.6.2.3]"]
["ENSRNOG00000069960",130,71.4874831636391,10.9375849240367,303,164.425347314033,25.157078139047,0.434771671955823,-1.20167015190081,{"v":1.06267871699468E-16,"d":"1.06E-16"},{"v":1.30920559956716e-15,"d":"1.31E-15"},"down","yes","5_8S_rRNA","rRNA","chr3:2234750-2234902:+","gi|954258002|gb|KRX51787.1|",138,{"v":1E-8,"d":"1.00E-08"},"hypothetical protein T09_8305 [Trichinella sp. T9]","gi|958786664|ref|XM_014867045.1|",153,{"v":3e-73,"d":"3.00E-73"},"PREDICTED: Equus asinus translation initiation factor IF-2-like (LOC106847650), mRNA",".",".",".",".",".",".",".",".","pfam05346","DUF747","Eukaryotic membrane protein family. This family is a family of eukaryotic membrane proteins. It was previously annotated as including a putative receptor for human cytomegalovirus gH but this has has since been disputed. Analysis of the mouse Tapt1 protein (transmembrane anterior posterior transformation 1) has shown it to be involved in patterning of the vertebrate axial skeleton.",".",".",".",".","."]
["ENSRNOG00000003802",150,11.089886025453,12.6202902969655,352,25.6813572098133,29.2253845047675,0.431826321905423,-1.21147690959773,{"v":2.23575153807771E-19,"d":"2.24E-19"},{"v":3.29765890069083e-18,"d":"3.30E-18"},"down","yes","Pttg1","protein_coding","chr10:27893689-27904837:-","gi|11761541|ref|NP_071786.1|",921,{"v":2E-121,"d":"2.00E-121"},"securin [Rattus norvegicus]","gi|165970625|gb|BC158551.1|",1044,0,"Rattus norvegicus pituitary tumor-transforming 1, mRNA (cDNA clone MGC:187213 IMAGE:9032805), complete cds","P97613",359,{"v":6e-123,"d":"6.00E-123"},"Securin",".",".",".",".","pfam04856","Securin","Securin sister-chromatid separation inhibitor. Securin is also known as pituitary tumor-transforming gene product. Over-expression of securin is associated with a number of tumors, and it has been proposed that this may be due to erroneous chromatid separation leading to chromosome gain or loss.","GO:0001558|regulation of cell growth;GO:0006281|DNA repair;GO:0007059|chromosome segregation;GO:0007064|mitotic sister chromatid cohesion;GO:0008285|negative regulation of cell proliferation;GO:0010951|negative regulation of endopeptidase activity;GO:0045143|homologous chromosome segregation;GO:0051301|cell division;GO:2000816|negative regulation of mitotic sister chromatid separation;","GO:0005634|nucleus;GO:0005737|cytoplasm;GO:0005829|cytosol;","GO:0004869|cysteine-type endopeptidase inhibitor activity;GO:0005515|protein binding;GO:0017124|SH3 domain binding;GO:0031072|heat shock protein binding;GO:0043022|ribosome binding;","K06635","PTTG; securin"]
["ENSRNOG00000068505",112,1.41531241940536,9.42315008840092,263,3.27966532262702,21.8360117180507,0.431541721541176,-1.21242804869102,{"v":6.96227810610606e-15,"d":"6.96E-15"},{"v":7.50525221727539e-14,"d":"7.51E-14"},"down","yes","Insl3","protein_coding","chr16:18384829-18400560:+","gi|300116243|ref|NP_036987.2|",5559,0,"tyrosine-protein kinase JAK3 [Rattus norvegicus]","gi|672079514|ref|XM_008771064.1|",4891,0,"PREDICTED: Rattus norvegicus Janus kinase 3 (Jak3), transcript variant X1, mRNA","Q63272",2119,0,"Tyrosine-protein kinase JAK3",".",".",".",".","pfam07714","Pkinase_Tyr","Protein tyrosine kinase.",".",".",".",".","."]
["ENSRNOG00000013727",187,3.40621243491744,15.7332952368836,441,7.92698793926918,36.6147572914843,0.429698198232843,-1.2186043671262,{"v":4.42683707656029e-24,"d":"4.43E-24"},{"v":8.5781469146023e-23,"d":"8.58E-23"},"down","yes","ENSRNOG00000013727","protein_coding","chr9:111407191-111440924:-","gi|564370209|ref|XP_006245719.1|",3291,0,"PREDICTED: kinetochore protein NDC80 homolog isoform X1 [Rattus norvegicus]","gi|672066324|ref|XM_006245657.2|",3370,0,"PREDICTED: Rattus norvegicus NDC80 kinetochore complex component (Ndc80), transcript variant X1, mRNA","Q9D0F1",1142,0,"Kinetochore protein NDC80 homolog","SPBC11C11.03",142,{"v":4e-34,"d":"4.00E-34"},"COG5185","pfam03801","Ndc80_HEC","HEC/Ndc80p family. Members of this family are components of the mitotic spindle. It has been shown that Ndc80/HEC from yeast is part of a complex called the Ndc80p complex. This complex is thought to bind to the microtubules of the spindle.","GO:0000132|establishment of mitotic spindle orientation;GO:0007052|mitotic spindle organization;GO:0007057|spindle assembly involved in female meiosis I;GO:0007059|chromosome segregation;GO:0008150|biological_process;GO:0008315|G2/MI transition of meiotic cell cycle;GO:0008608|attachment of spindle microtubules to kinetochore;GO:0031647|regulation of protein stability;GO:0040038|polar body extrusion after meiotic divisions;GO:0051225|spindle assembly;GO:0051298|centrosome duplication;GO:0051301|cell division;GO:0051310|metaphase plate congression;GO:0051311|meiotic metaphase plate congression;GO:0051315|attachment of mitotic spindle microtubules to kinetochore;GO:0051383|kinetochore organization;GO:0090267|positive regulation of mitotic cell cycle spindle assembly checkpoint;GO:1905342|positive regulation of protein localization to kinetochore;","GO:0000776|kinetochore;GO:0000940|condensed chromosome outer kinetochore;GO:0005575|cellular_component;GO:0005654|nucleoplasm;GO:0005737|cytoplasm;GO:0005813|centrosome;GO:0031262|Ndc80 complex;","GO:0003674|molecular_function;GO:0030332|cyclin binding;GO:0042802|identical protein binding;","K11547","NDC80, HEC1, TID3; kinetochore protein NDC80"]
["ENSRNOG00000016403",137,7.47505305094802,11.5265318045618,324,17.4452905383074,26.9006380100701,0.428485443365578,-1.22268190138042,{"v":3.36028550668305E-18,"d":"3.36E-18"},{"v":4.52411325399983e-17,"d":"4.52E-17"},"down","yes","Olah","protein_coding","chr17:74877655-74902518:+","gi|12083671|ref|NP_073196.1|",1365,0,"S-acyl fatty acid synthase thioesterase, medium chain [Rattus norvegicus]","gi|672082480|ref|XM_008771886.1|",1385,0,"PREDICTED: Rattus norvegicus oleoyl-ACP hydrolase (Olah), transcript variant X1, mRNA","P08635",530,0,"S-acyl fatty acid synthase thioesterase, medium chain","alr2045",145,{"v":5e-39,"d":"5.00E-39"},"COG3208","pfam00975","Thioesterase","Thioesterase domain. Peptide synthetases are involved in the non-ribosomal synthesis of peptide antibiotics. Next to the operons encoding these enzymes, in almost all cases, are genes that encode proteins that have similarity to the type II fatty acid thioesterases of vertebrates. There are also modules within the peptide synthetases that also share this similarity. With respect to antibiotic production, thioesterases are required for the addition of the last amino acid to the peptide antibiotic, thereby forming a cyclic antibiotic. Thioesterases (non-integrated) have molecular masses of 25-29 kDa.","GO:0008610|lipid biosynthetic process;GO:0051792|medium-chain fatty acid biosynthetic process;","GO:0005829|cytosol;","GO:0004320|oleoyl-[acyl-carrier-protein] hydrolase activity;GO:0016290|palmitoyl-CoA hydrolase activity;GO:0016295|myristoyl-[acyl-carrier-protein] hydrolase activity;GO:0016296|palmitoyl-[acyl-carrier-protein] hydrolase activity;GO:0016297|acyl-[acyl-carrier-protein] hydrolase activity;GO:0047381|dodecanoyl-[acyl-carrier-protein] hydrolase activity;GO:0102991|myristoyl-CoA hydrolase activity;","K01071","MCH; medium-chain acyl-[acyl-carrier-protein] hydrolase [EC:3.1.2.21]"]
["ENSRNOG00000009564",474,9.33960593405411,39.880117338411,1121,21.7969289106373,93.0728864484216,0.428482653329028,-1.22269129536348,{"v":6.92576107517994e-59,"d":"6.93E-59"},{"v":3.78840452521762e-57,"d":"3.79E-57"},"down","yes","Prr15","protein_coding","chr4:83431758-83437436:+","gi|149033319|gb|EDL88120.1|",859,{"v":6E-103,"d":"6.00E-103"},"similar to RIKEN cDNA E130201N16 (predicted), isoform CRA_a [Rattus norvegicus]","gi|354799084|gb|JN963585.1|",1559,0,"Mus musculus targeted non-conditional, lacZ-tagged mutant allele Prr15:tm1e(KOMP)Wtsi; transgenic","Q9D1T5",204,{"v":8e-59,"d":"8.00E-59"},"Proline-rich protein 15",".",".",".",".","pfam15321","ATAD4","ATPase family AAA domain containing 4. ATAD4 is a family of proteins is found in eukaryotes. The family is also known as PRR15L, or proline-rich 15-like. ATAD4 is expressed almost exclusively in post-mitotic cells both during foetal development and in adult tissues, such as the intestinal epithelium and the testis. Its expression in mouse and human gastrointestinal tumors is linked, directly or indirectly, to the disruption of the Wnt signaling pathway.",".",".",".",".","."]
["ENSRNOG00000007546",138,4.73132317571649,11.6106670732082,327,11.0634547643214,27.1497179916448,0.427653321363462,-1.22548635017623,{"v":2.04902789785812E-18,"d":"2.05E-18"},{"v":2.79805820021189e-17,"d":"2.80E-17"},"down","yes","Asns","protein_coding","chr4:35785237-35803423:-","gi|149064973|gb|EDM15049.1|",2902,0,"asparagine synthetase, isoform CRA_a [Rattus norvegicus]","gi|672048825|ref|XM_006236089.2|",2426,0,"PREDICTED: Rattus norvegicus asparagine synthetase (glutamine-hydrolyzing) (Asns), transcript variant X1, mRNA","P49088",1106,0,"Asparagine synthetase [glutamine-hydrolyzing]","L00396",330,{"v":9E-102,"d":"9.00E-102"},"COG0367","pfam00733","Asn_synthase","Asparagine synthase. This family is always found associated with pfam00310. Members of this family catalyse the conversion of aspartate to asparagine.","GO:0001889|liver development;GO:0006520|cellular amino acid metabolic process;GO:0006529|asparagine biosynthetic process;GO:0006541|glutamine metabolic process;GO:0009416|response to light stimulus;GO:0009612|response to mechanical stimulus;GO:0009636|response to toxic substance;GO:0031427|response to methotrexate;GO:0031667|response to nutrient levels;GO:0032354|response to follicle-stimulating hormone;GO:0032870|cellular response to hormone stimulus;GO:0042149|cellular response to glucose starvation;GO:0043066|negative regulation of apoptotic process;GO:0043200|response to amino acid;GO:0045931|positive regulation of mitotic cell cycle;GO:0070981|L-asparagine biosynthetic process;","GO:0005829|cytosol;","GO:0004066|asparagine synthase (glutamine-hydrolyzing) activity;GO:0005524|ATP binding;GO:0042802|identical protein binding;","K01953","asnB, ASNS; asparagine synthase (glutamine-hydrolysing) [EC:6.3.5.4]"]
["ENSRNOG00000061813",1903,90.3552010350842,160.109416234169,4535,212.486402641341,376.525905480457,0.425228155363879,-1.23369097059818,{"v":1.22262792441153E-235,"d":"1.22E-235"},{"v":3.34389903955625E-233,"d":"3.34E-233"},"down","yes","Ly6c","protein_coding","chr7:106959511-106963329:-","gi|9910398|ref|NP_064488.1|",500,{"v":1e-57,"d":"1.00E-57"},"Ly6-C antigen precursor [Rattus norvegicus]","gi|672075999|ref|XM_003751343.2|",727,0,"PREDICTED: Rattus norvegicus lymphocyte antigen 6B-like (LOC100911104), mRNA","Q63317",129,{"v":4e-34,"d":"4.00E-34"},"Lymphocyte antigen 6B",".",".",".",".","pfam00021","UPAR_LY6","u-PAR/Ly-6 domain. This extracellular disulphide bond rich domain is related to pfam00087.","GO:0095500|acetylcholine receptor signaling pathway;GO:2000272|negative regulation of signaling receptor activity;","GO:0005886|plasma membrane;GO:0045202|synapse;","GO:0030550|acetylcholine receptor inhibitor activity;GO:0033130|acetylcholine receptor binding;","K06846","LY6D_E_F_G6_H; lymphocyte antigen 6 complex locus protein D/E/F/G6/H"]
["ENSRNOG00000009342",205,13.8202965324675,17.2477300725195,489,32.5320809268268,40.6000369966799,0.424820550629793,-1.2350745369031,{"v":4.68831402914989e-27,"d":"4.69E-27"},{"v":1.03886672729922e-25,"d":"1.04E-25"},"down","yes","Fcnb","protein_coding","chr3:11393739-11402151:-","gi|16758442|ref|NP_446086.1|",1695,0,"ficolin-2 precursor [Rattus norvegicus]","gi|298888542|emb|FQ220557.1|",1162,0,"Rattus norvegicus TL0ADA42YH06 mRNA sequence","P57756",657,0,"Ficolin-2",".",".",".",".","pfam00147","Fibrinogen_C","Fibrinogen beta and gamma chains, C-terminal globular domain.","GO:0001867|complement activation, lectin pathway;GO:0002752|cell surface pattern recognition receptor signaling pathway;GO:0007186|G protein-coupled receptor signaling pathway;GO:0032757|positive regulation of interleukin-8 production;GO:0034394|protein localization to cell surface;GO:0043654|recognition of apoptotic cell;GO:0046597|negative regulation of viral entry into host cell;","GO:0005581|collagen trimer;GO:0005615|extracellular space;GO:0031232|extrinsic component of external side of plasma membrane;GO:0062023|collagen-containing extracellular matrix;","GO:0001664|G protein-coupled receptor binding;GO:0003823|antigen binding;GO:0005102|signaling receptor binding;GO:0030246|carbohydrate binding;GO:0033691|sialic acid binding;GO:0038187|pattern recognition receptor activity;GO:0046872|metal ion binding;GO:0097367|carbohydrate derivative binding;","K10104","FCN; ficolin"]
["ENSRNOG00000002217",517,70.4990824800775,43.4979338902078,1237,166.45701631979,102.70397906931,0.423527250690577,-1.23947329611775,{"v":3.72660857380744e-66,"d":"3.73E-66"},{"v":2.36245596225513e-64,"d":"2.36E-64"},"down","yes","Plac8","protein_coding","chr14:9063048-9074264:+","gi|157820945|ref|NP_001101823.1|",517,{"v":8e-64,"d":"8.00E-64"},"placenta-specific gene 8 protein [Rattus norvegicus]","gi|157820944|ref|NM_001108353.1|",605,0,"Rattus norvegicus placenta-specific 8 (Plac8), mRNA","Q9JI48",202,{"v":1e-64,"d":"1.00E-64"},"Placenta-specific gene 8 protein",".",".",".",".","pfam04749","PLAC8","PLAC8 family. This family includes the Placenta-specific gene 8 protein.","GO:0008284|positive regulation of cell proliferation;GO:0009409|response to cold;GO:0040015|negative regulation of multicellular organism growth;GO:0042742|defense response to bacterium;GO:0043066|negative regulation of apoptotic process;GO:0045944|positive regulation of transcription by RNA polymerase II;GO:0050873|brown fat cell differentiation;GO:0120162|positive regulation of cold-induced thermogenesis;",".","GO:0003682|chromatin binding;",".","."]
["ENSRNOG00000001250",137,4.81073948437472,11.5265318045618,330,11.4352245297243,27.3987979732195,0.42069479894075,-1.24915411274161,{"v":4.34621397142815e-19,"d":"4.35E-19"},{"v":6.25628246491637E-18,"d":"6.26E-18"},"down","yes","Lfng","protein_coding","chr12:14018333-14039008:-","gi|19173748|ref|NP_596884.1|",1693,0,"beta-1,3-N-acetylglucosaminyltransferase lunatic fringe precursor [Rattus norvegicus]","gi|47575871|ref|NM_133393.2|",1837,0,"Rattus norvegicus LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase (Lfng), mRNA","Q924T4",656,0,"Beta-1,3-N-acetylglucosaminyltransferase lunatic fringe",".",".",".",".","pfam02434","Fringe","Fringe-like. The drosophila protein fringe (FNG) is a glucosaminyltransferase that controls the response of the Notch receptor to specific ligands. FNG is localized to the Golgi apparatus (not secreted as previously thought). Modification of Notch occurs through glycosylation by FNG. The xenopus homologue, lunatic fringe, has been implicated in a variety of functions.","GO:0001541|ovarian follicle development;GO:0001756|somitogenesis;GO:0002315|marginal zone B cell differentiation;GO:0007386|compartment pattern specification;GO:0008150|biological_process;GO:0008593|regulation of Notch signaling pathway;GO:0014807|regulation of somitogenesis;GO:0030217|T cell differentiation;GO:0032092|positive regulation of protein binding;GO:0045747|positive regulation of Notch signaling pathway;GO:0051446|positive regulation of meiotic cell cycle;GO:1902367|negative regulation of Notch signaling pathway involved in somitogenesis;","GO:0005575|cellular_component;GO:0030173|integral component of Golgi membrane;","GO:0003674|molecular_function;GO:0008375|acetylglucosaminyltransferase activity;GO:0033829|O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity;GO:0046872|metal ion binding;","K05948","FNG; fringe [EC:2.4.1.222]"]
["ENSRNOG00000038740",109,3.15579638075072,9.17074428246161,263,7.51411277290115,21.8360117180507,0.419982568285609,-1.25159864597169,{"v":1.43611910127553E-15,"d":"1.44E-15"},{"v":1.61164103856121E-14,"d":"1.61E-14"},"down","yes","Gimap7","protein_coding","chr4:77670367-77675272:+","gi|66730266|ref|NP_001019499.1|",1523,0,"GTPase, IMAP family member 7 [Rattus norvegicus]","gi|60551436|gb|BC091210.1|",1192,0,"Rattus norvegicus GTPase, IMAP family member 7, mRNA (cDNA clone MGC:108919 IMAGE:7381387), complete cds","Q8NHV1",327,{"v":6e-104,"d":"6.00E-104"},"GTPase IMAP family member 7",".",".",".",".","pfam04548","AIG1","AIG1 family. Arabidopsis protein AIG1 appears to be involved in plant resistance to bacteria.","GO:0046039|GTP metabolic process;","GO:0005794|Golgi apparatus;GO:0005811|lipid droplet;GO:0005829|cytosol;GO:0043231|intracellular membrane-bounded organelle;","GO:0003924|GTPase activity;GO:0005525|GTP binding;GO:0042802|identical protein binding;GO:0042803|protein homodimerization activity;",".","."]
["ENSRNOG00000062245",104,4.53371395814996,8.75006793922943,251,10.797767767747,20.8396917917518,0.419875112677655,-1.251967817266,{"v":6.19644828301972e-15,"d":"6.20E-15"},{"v":6.7175207396996e-14,"d":"6.72E-14"},"down","yes","Ndufa10l1","protein_coding","chr6:59879312-59881241:-","gi|32996721|ref|NP_872612.1|",1839,0,"NADH dehydrogenase (ubiquinone) 1 alpha subcomplex 10-like [Rattus norvegicus]","gi|30171808|gb|AY260163.1|",1872,0,"Rattus norvegicus NADH dehydrogenase 1 alpha subcomplex 10-like protein mRNA, complete cds","Q561S0",704,0,"NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial","BS_yaaG",60.8,{"v":1e-09,"d":"1.00E-09"},"COG1428","pfam01712","dNK","Deoxynucleoside kinase. This family consists of various deoxynucleoside kinases cytidine EC:2.7.1.74, guanosine EC:2.7.1.113, adenosine EC:2.7.1.76 and thymidine kinase EC:2.7.1.21 (which also phosphorylates deoxyuridine and deoxycytosine.) These enzymes catalyse the production of deoxynucleotide 5'-monophosphate from a deoxynucleoside. Using ATP and yielding ADP in the process.","GO:0006120|mitochondrial electron transport, NADH to ubiquinone;GO:0032981|mitochondrial respiratory chain complex I assembly;","GO:0005737|cytoplasm;GO:0005747|mitochondrial respiratory chain complex I;GO:0005759|mitochondrial matrix;",".","K03954","NDUFA10; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 10"]
["ENSRNOG00000019065",113,1.8781677908035,9.50728535704736,276,4.52693763430947,22.9153583048745,0.414887047828746,-1.2692094758193,{"v":1.37356758902866E-16,"d":"1.37E-16"},{"v":1.67924924890366E-15,"d":"1.68E-15"},"down","yes","Zfp385b","protein_coding","chr3:62355196-62640510:-","gi|157819921|ref|NP_001101206.1|",1842,0,"zinc finger protein 385B [Rattus norvegicus]","gi|157819920|ref|NM_001107736.1|",3789,0,"Rattus norvegicus zinc finger protein 385B (Zfp385b), mRNA","Q8BXJ8",681,0,"Zinc finger protein 385B",".",".",".",".","pfam12874","zf-met","Zinc-finger of C2H2 type. This is a zinc-finger domain with the CxxCx(12)Hx(6)H motif, found in multiple copies in a wide range of proteins from plants to metazoans. Some member proteins, particularly those from plants, are annotated as being RNA-binding.","GO:0072332|intrinsic apoptotic signaling pathway by p53 class mediator;","GO:0005634|nucleus;","GO:0002039|p53 binding;GO:0003676|nucleic acid binding;GO:0008270|zinc ion binding;",".","."]
["ENSRNOG00000018938",210,5.38014811685497,17.6684064157517,522,13.1972950042636,43.3399167940018,0.407670519990407,-1.29452446036008,{"v":7.79994366268209e-31,"d":"7.80E-31"},{"v":2.07981117563193E-29,"d":"2.08E-29"},"down","yes","Mkx","protein_coding","chr17:55077540-55156124:-","gi|148691080|gb|EDL23027.1|",1927,0,"mohawk, partial [Mus musculus]","gi|672030195|ref|XM_008774010.1|",3133,0,"PREDICTED: Rattus norvegicus mohawk homeobox (Mkx), transcript variant X2, mRNA","Q8BIA3",662,0,"Homeobox protein Mohawk",".",".",".",".","pfam05920","Homeobox_KN","Homeobox KN domain. This is a homeobox transcription factor KN domain conserved from fungi to human and plants.","GO:0000122|negative regulation of transcription by RNA polymerase II;GO:0002932|tendon sheath development;GO:0006357|regulation of transcription by RNA polymerase II;GO:0007517|muscle organ development;GO:0010468|regulation of gene expression;GO:0010628|positive regulation of gene expression;GO:0030199|collagen fibril organization;GO:0030279|negative regulation of ossification;GO:0032331|negative regulation of chondrocyte differentiation;GO:0032967|positive regulation of collagen biosynthetic process;GO:0035990|tendon cell differentiation;GO:0035992|tendon formation;GO:0036077|intratendonous ossification;GO:0045599|negative regulation of fat cell differentiation;GO:0045662|negative regulation of myoblast differentiation;GO:0045944|positive regulation of transcription by RNA polymerase II;GO:0048468|cell development;GO:0071260|cellular response to mechanical stimulus;","GO:0005634|nucleus;","GO:0000978|RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0000981|DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001227|DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0001228|DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0061629|RNA polymerase II sequence-specific DNA-binding transcription factor binding;","K24890","MKX; homeobox protein Mohawk"]
["ENSRNOG00000057470",191,10.7060868164353,16.0698363114694,475,26.2742596597809,39.4376637493312,0.407474347710111,-1.29521885663888,{"v":3.13566784141375e-28,"d":"3.14E-28"},{"v":7.28550610039037e-27,"d":"7.29E-27"},"down","yes","Pla2g12a","protein_coding","chr2:218436513-218452740:+","gi|672044253|ref|XP_008759737.1|",819,{"v":6e-104,"d":"6.00E-104"},"PREDICTED: group XIIA secretory phospholipase A2 isoform X1 [Rattus norvegicus]","gi|672044252|ref|XM_008761515.1|",1501,0,"PREDICTED: Rattus norvegicus phospholipase A2, group XIIA (Pla2g12a), transcript variant X1, mRNA","Q9EPR2",314,{"v":2e-103,"d":"2.00E-103"},"Group XIIA secretory phospholipase A2",".",".",".",".","pfam06951","PLA2G12","Group XII secretory phospholipase A2 precursor (PLA2G12). This family consists of several group XII secretory phospholipase A2 precursor (PLA2G12) (EC:3.1.1.4) proteins. Group XII and group V PLA(2)s are thought to participate in helper T cell immune response through release of immediate second signals and generation of downstream eicosanoids.","GO:0006644|phospholipid metabolic process;GO:0016042|lipid catabolic process;GO:0050482|arachidonic acid secretion;","GO:0005576|extracellular region;GO:0005783|endoplasmic reticulum;GO:0005794|Golgi apparatus;","GO:0004623|phospholipase A2 activity;GO:0005509|calcium ion binding;","K01047","PLA2G, SPLA2; secretory phospholipase A2 [EC:3.1.1.4]"]
["ENSRNOG00000020150",384,27.9722451603738,32.3079431602317,958,68.8654032752049,79.5395407828617,0.406187197489994,-1.29978332647134,{"v":1.77212029687008e-55,"d":"1.77E-55"},{"v":9.07148701880428e-54,"d":"9.07E-54"},"down","yes","Il18bp","protein_coding","chr1:156372883-156374963:-","gi|149068682|gb|EDM18234.1|",991,{"v":1e-131,"d":"1.00E-131"},"interleukin 18 binding protein, isoform CRA_b [Rattus norvegicus]","gi|672038104|ref|XM_008759805.1|",776,0,"PREDICTED: Rattus norvegicus interleukin 18 binding protein (Il18bp), transcript variant X1, mRNA","Q9Z0M9",277,{"v":2E-90,"d":"2.00E-90"},"Interleukin-18-binding protein",".",".",".",".","pfam05566","Pox_vIL-18BP","Orthopoxvirus interleukin 18 binding protein. Interleukin-18 (IL-18) is a proinflammatory cytokine that plays a key role in the activation of natural killer and T helper 1 cell responses principally by inducing interferon-gamma (IFN-gamma). Several poxvirus genes encode proteins with sequence similarity to IL-18BPs. It has been shown that vaccinia, ectromelia and cowpox viruses secrete from infected cells a soluble IL-18BP (vIL-18BP) that may modulate the host antiviral response. The expression of vIL-18BPs by distinct poxvirus genera that cause local or general viral dissemination, or persistent or acute infections in the host, emphasises the importance of IL-18 in response to viral infections.","GO:0032496|response to lipopolysaccharide;GO:0042088|T-helper 1 type immune response;GO:0070301|cellular response to hydrogen peroxide;GO:0071356|cellular response to tumor necrosis factor;","GO:0005615|extracellular space;","GO:0005515|protein binding;GO:0042007|interleukin-18 binding;","K25565","IL18BP; interleukin-18-binding protein"]
["ENSRNOG00000016949",171,10.4709832158229,14.3871309385407,427,25.8023173538105,35.4523840441356,0.405815612304937,-1.30110372619091,{"v":1.0334507850042e-25,"d":"1.03E-25"},{"v":2.17422904473292E-24,"d":"2.17E-24"},"down","yes","Slc25a33","pseudogene","chr5:160195042-160219961:-","gi|189011685|ref|NP_001121046.1|",1640,0,"solute carrier family 25 member 33 [Rattus norvegicus]","gi|189011684|ref|NM_001127574.1|",1351,0,"Rattus norvegicus solute carrier family 25 member 33 (Slc25a33), mRNA","Q3TZX3",612,0,"Solute carrier family 25 member 33",".",".",".",".","pfam00153","Mito_carr","Mitochondrial carrier protein.","GO:0000002|mitochondrial genome maintenance;GO:0002082|regulation of oxidative phosphorylation;GO:0006390|mitochondrial transcription;GO:0006864|pyrimidine nucleotide transport;GO:0007005|mitochondrion organization;GO:0008284|positive regulation of cell proliferation;GO:0030307|positive regulation of cell growth;GO:0031930|mitochondria-nucleus signaling pathway;GO:0032869|cellular response to insulin stimulus;GO:0034551|mitochondrial respiratory chain complex III assembly;GO:0051881|regulation of mitochondrial membrane potential;GO:1903426|regulation of reactive oxygen species biosynthetic process;GO:1990314|cellular response to insulin-like growth factor stimulus;GO:1990519|pyrimidine nucleotide import into mitochondrion;","GO:0016021|integral component of membrane;GO:0031966|mitochondrial membrane;","GO:0015218|pyrimidine nucleotide transmembrane transporter activity;","K15116","SLC25A33_36, RIM2; solute carrier family 25, member 33/36"]
["ENSRNOG00000014850",549,22.5208495791778,46.1902624868938,1371,55.4995375814961,113.829551579648,0.405784454439967,-1.30121449823034,{"v":9.84761065392327e-79,"d":"9.85E-79"},{"v":7.54132654917047e-77,"d":"7.54E-77"},"down","yes","Amhr2","protein_coding","chr7:133579393-133588258:+","gi|453178|emb|CAA50731.1|",2310,0,"put. anti-mullerian hormone receptor [Rattus norvegicus]","gi|13591889|ref|NM_030998.1|",1920,0,"Rattus norvegicus anti-Mullerian hormone receptor, type II (Amhr2), mRNA","Q62893",894,0,"Anti-Muellerian hormone type-2 receptor",".",".",".",".","pfam00069","Pkinase","Protein kinase domain.","GO:0006468|protein phosphorylation;GO:0007178|transmembrane receptor protein serine/threonine kinase signaling pathway;GO:0007179|transforming growth factor beta receptor signaling pathway;GO:0007548|sex differentiation;GO:0008584|male gonad development;GO:0008585|female gonad development;GO:0032924|activin receptor signaling pathway;GO:0071363|cellular response to growth factor stimulus;GO:1902613|negative regulation of anti-Mullerian hormone signaling pathway;GO:1990262|anti-Mullerian hormone signaling pathway;","GO:0005886|plasma membrane;GO:0005887|integral component of plasma membrane;GO:0016021|integral component of membrane;GO:0043235|receptor complex;GO:0048179|activin receptor complex;","GO:0004674|protein serine/threonine kinase activity;GO:0004675|transmembrane receptor protein serine/threonine kinase activity;GO:0005026|transforming growth factor beta receptor activity, type II;GO:0005524|ATP binding;GO:0017002|activin-activated receptor activity;GO:0042562|hormone binding;GO:0046872|metal ion binding;GO:0048185|activin binding;GO:1990272|anti-Mullerian hormone receptor activity;","K04672","AMHR2; anti-mullerian hormone receptor type-2 [EC:2.7.11.30]"]
["ENSRNOG00000008040",108,5.30759872302288,9.08660901381518,270,13.0941579098861,22.4171983417251,0.40534097416189,-1.30279207634368,{"v":7.16320776886034e-17,"d":"7.16E-17"},{"v":8.92214206053829e-16,"d":"8.92E-16"},"down","yes","Pimreg","protein_coding","chr10:56669675-56674791:+","gi|166795897|ref|NP_001107253.2|",995,{"v":7e-129,"d":"7.00E-129"},"protein FAM64A [Rattus norvegicus]","gi|166795896|ref|NM_001113781.2|",1428,0,"Rattus norvegicus family with sequence similarity 64, member A (Fam64a), mRNA","Q8BFY7",359,{"v":2E-119,"d":"2.00E-119"},"Protein PIMREG",".",".",".",".","pfam07326","DUF1466","Protein of unknown function (DUF1466). This family consists of several hypothetical mammalian proteins of around 240 residues in length.",".","GO:0005654|nucleoplasm;GO:0005730|nucleolus;",".",".","."]
["ENSRNOG00000065741",145,3.90512610554844,12.1996139537333,363,9.64746407507732,30.1386777705415,0.404782653260841,-1.30478062943713,{"v":3.43468228279347E-22,"d":"3.43E-22"},{"v":6.01071496524308e-21,"d":"6.01E-21"},"down","yes","Il7r","protein_coding","chr2:58454217-58477757:-","gi|157823237|ref|NP_001099888.1|",2463,0,"interleukin-7 receptor subunit alpha precursor [Rattus norvegicus]","gi|157823236|ref|NM_001106418.1|",3124,0,"Rattus norvegicus interleukin 7 receptor (Il7r), mRNA","P16872",743,0,"Interleukin-7 receptor subunit alpha",".",".",".",".","pfam00041","fn3","Fibronectin type III domain.",".",".",".",".","."]
["ENSRNOG00000053661",164,10.6058294066223,13.7981840580156,411,26.2290218875765,34.1239574757371,0.404354743081204,-1.30630656051992,{"v":5.92871870342313e-25,"d":"5.93E-25"},{"v":1.19984900189246E-23,"d":"1.20E-23"},"down","yes","Klra17","protein_coding","chr4:163368380-163455261:-","gi|672051537|ref|XP_008761655.1|",1409,0,"PREDICTED: killer cell lectin-like receptor 7 isoform X6 [Rattus norvegicus]","gi|672018818|ref|XM_003753951.3|",1045,0,"PREDICTED: Rattus norvegicus similar to immunoreceptor Ly49si3 (LOC690097), transcript variant X1, mRNA","Q60654",309,{"v":6e-101,"d":"6.00E-101"},"Killer cell lectin-like receptor 7",".",".",".",".","pfam08391","Ly49","Ly49-like protein, N-terminal region. The sequences making up this family are annotated as, or are similar to, Ly49 receptors. These are type II transmembrane receptors expressed by mouse natural killer (NK) cells. They are classified as being activating (e.g.Ly49D and H) or inhibitory (e.g. Ly49A and G), depending on their effect on NK cell function. They are members of the C-type lectin receptor superfamily, and in fact in many family members this region is found immediately N-terminal to a lectin C-type domain (pfam00059).",".","GO:0016021|integral component of membrane;",".",".","."]
["ENSRNOG00000058539",219,5.60901790976245,18.4256238335696,552,13.9515119055552,45.8307166097491,0.40203656404644,-1.31460137863331,{"v":2.97596569118445e-33,"d":"2.98E-33"},{"v":8.62040155285125e-32,"d":"8.62E-32"},"down","yes","Ccnb1","protein_coding","chr2:31912193-31921172:-","gi|25282457|ref|NP_741988.1|",2040,0,"G2/mitotic-specific cyclin-B1 [Rattus norvegicus]","gi|694875687|ref|NM_171991.3|",3240,0,"Rattus norvegicus cyclin B1 (Ccnb1), mRNA","P30277",790,0,"G2/mitotic-specific cyclin-B1","SPBC582.03",191,{"v":6E-51,"d":"6.00E-51"},"COG5024","pfam00134","Cyclin_N","Cyclin, N-terminal domain. Cyclins regulate cyclin dependent kinases (CDKs). Human cyclin-O is a Uracil-DNA glycosylase that is related to other cyclins. Cyclins contain two domains of similar all-alpha fold, of which this family corresponds with the N-terminal domain.","GO:0000079|regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0000278|mitotic cell cycle;GO:0001556|oocyte maturation;GO:0001701|in utero embryonic development;GO:0001933|negative regulation of protein phosphorylation;GO:0006468|protein phosphorylation;GO:0007052|mitotic spindle organization;GO:0007080|mitotic metaphase plate congression;GO:0007283|spermatogenesis;GO:0009410|response to xenobiotic stimulus;GO:0009612|response to mechanical stimulus;GO:0009636|response to toxic substance;GO:0010629|negative regulation of gene expression;GO:0010971|positive regulation of G2/M transition of mitotic cell cycle;GO:0031442|positive regulation of mRNA 3'-end processing;GO:0033129|positive regulation of histone phosphorylation;GO:0042246|tissue regeneration;GO:0044772|mitotic cell cycle phase transition;GO:0045737|positive regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0045787|positive regulation of cell cycle;GO:0045931|positive regulation of mitotic cell cycle;GO:0046680|response to DDT;GO:0048146|positive regulation of fibroblast proliferation;GO:0048565|digestive tract development;GO:0051301|cell division;GO:0051726|regulation of cell cycle;GO:0051987|positive regulation of attachment of spindle microtubules to kinetochore;GO:0055015|ventricular cardiac muscle cell development;GO:0060045|positive regulation of cardiac muscle cell proliferation;GO:0060623|regulation of chromosome condensation;GO:0065003|protein-containing complex assembly;GO:0071283|cellular response to iron(III) ion;GO:0071398|cellular response to fatty acid;GO:0071407|cellular response to organic cyclic compound;GO:0071456|cellular response to hypoxia;GO:0090266|regulation of mitotic cell cycle spindle assembly checkpoint;GO:1904145|negative regulation of meiotic cell cycle process involved in oocyte maturation;GO:1905448|positive regulation of mitochondrial ATP synthesis coupled electron transport;GO:2000775|histone H3-S10 phosphorylation involved in chromosome condensation;","GO:0000307|cyclin-dependent protein kinase holoenzyme complex;GO:0000922|spindle pole;GO:0000940|condensed chromosome outer kinetochore;GO:0005634|nucleus;GO:0005737|cytoplasm;GO:0005759|mitochondrial matrix;GO:0005813|centrosome;GO:0005829|cytosol;GO:0016020|membrane;GO:0097125|cyclin B1-CDK1 complex;","GO:0005113|patched binding;GO:0016538|cyclin-dependent protein serine/threonine kinase regulator activity;GO:0019901|protein kinase binding;GO:0035173|histone kinase activity;GO:0044389|ubiquitin-like protein ligase binding;GO:0044877|protein-containing complex binding;GO:0061575|cyclin-dependent protein serine/threonine kinase activator activity;","K05868","CCNB1; G2/mitotic-specific cyclin-B1"]
["ENSRNOG00000015423",189,5.38124053271626,15.9015657741765,481,13.5146611548157,39.9358237124806,0.398177983973998,-1.32851464100529,{"v":1.21471729488111E-29,"d":"1.21E-29"},{"v":3.02810465444694E-28,"d":"3.03E-28"},"down","yes","Ccna2","protein_coding","chr2:119426089-119433577:-","gi|118150676|ref|NP_446154.3|",2167,0,"cyclin-A2 [Rattus norvegicus]","gi|118150675|ref|NM_053702.3|",1691,0,"Rattus norvegicus cyclin A2 (Ccna2), mRNA","P51943",783,0,"Cyclin-A2","SPBC582.03",154,{"v":1e-38,"d":"1.00E-38"},"COG5024","pfam00134","Cyclin_N","Cyclin, N-terminal domain. Cyclins regulate cyclin dependent kinases (CDKs). Human cyclin-O is a Uracil-DNA glycosylase that is related to other cyclins. Cyclins contain two domains of similar all-alpha fold, of which this family corresponds with the N-terminal domain.","GO:0000079|regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0000086|G2/M transition of mitotic cell cycle;GO:0006275|regulation of DNA replication;GO:0007265|Ras protein signal transduction;GO:0016572|histone phosphorylation;GO:0031100|animal organ regeneration;GO:0032355|response to estradiol;GO:0033762|response to glucagon;GO:0036120|cellular response to platelet-derived growth factor stimulus;GO:0044320|cellular response to leptin stimulus;GO:0044772|mitotic cell cycle phase transition;GO:0044843|cell cycle G1/S phase transition;GO:0045893|positive regulation of transcription, DNA-templated;GO:0048146|positive regulation of fibroblast proliferation;GO:0071314|cellular response to cocaine;GO:0071373|cellular response to luteinizing hormone stimulus;GO:0071392|cellular response to estradiol stimulus;GO:0071407|cellular response to organic cyclic compound;GO:0071456|cellular response to hypoxia;GO:0071732|cellular response to nitric oxide;GO:0090102|cochlea development;GO:1990314|cellular response to insulin-like growth factor stimulus;","GO:0000307|cyclin-dependent protein kinase holoenzyme complex;GO:0001939|female pronucleus;GO:0001940|male pronucleus;GO:0005634|nucleus;GO:0005654|nucleoplasm;GO:0005737|cytoplasm;GO:0005829|cytosol;GO:0097124|cyclin A2-CDK2 complex;","GO:0003674|molecular_function;GO:0005515|protein binding;GO:0016538|cyclin-dependent protein serine/threonine kinase regulator activity;GO:0019901|protein kinase binding;GO:0019904|protein domain specific binding;","K06627","CCNA; cyclin-A"]
["ENSRNOG00000014312",106,22.1849215833888,8.9183384765223,270,55.7641749794157,22.4171983417251,0.397834659825559,-1.32975912394395,{"v":2.30435924190045e-17,"d":"2.30E-17"},{"v":2.94900478631193e-16,"d":"2.95E-16"},"down","yes","AC109737.1","TR_C_gene","chr4:70417612-70418013:+","gi|68533982|gb|AAH99166.1|",697,{"v":8E-90,"d":"8.00E-90"},"Tcrb protein [Rattus norvegicus]","gi|207192|gb|M63795.1|RATTCBC3",390,0,"Rattus norvegicus T-cell receptor beta-chain (Tcrb) gene, exons 1 through 4 and partial cds","P01852",235,{"v":5e-78,"d":"5.00E-78"},"T-cell receptor beta-1 chain C region",".",".",".",".","pfam07654","C1-set","Immunoglobulin C1-set domain.",".",".",".",".","."]
["ENSRNOG00000015131",219,18.687245267312,18.4256238335696,562,47.3235123884363,46.6609832149982,0.394882888529599,-1.34050324207607,{"v":8.3568518854383e-35,"d":"8.36E-35"},{"v":2.55579053567234e-33,"d":"2.56E-33"},"down","yes","Ube2c","protein_coding","chr3:153506636-153513339:+","gi|157818349|ref|NP_001100012.1|",787,{"v":7e-103,"d":"7.00E-103"},"ubiquitin-conjugating enzyme E2 C [Rattus norvegicus]","gi|157818348|ref|NM_001106542.1|",611,0,"Rattus norvegicus ubiquitin-conjugating enzyme E2C (Ube2c), mRNA","Q4R9D1",303,{"v":8e-103,"d":"8.00E-103"},"Ubiquitin-conjugating enzyme E2 C",".",".",".",".","pfam00179","UQ_con","Ubiquitin-conjugating enzyme. Proteins destined for proteasome-mediated degradation may be ubiquitinated. Ubiquitination follows conjugation of ubiquitin to a conserved cysteine residue of UBC homologues. TSG101 is one of several UBC homologues that lacks this active site cysteine.","GO:0000209|protein polyubiquitination;GO:0006511|ubiquitin-dependent protein catabolic process;GO:0010458|exit from mitosis;GO:0010994|free ubiquitin chain polymerization;GO:0016567|protein ubiquitination;GO:0030071|regulation of mitotic metaphase/anaphase transition;GO:0031145|anaphase-promoting complex-dependent catabolic process;GO:0031536|positive regulation of exit from mitosis;GO:0070936|protein K48-linked ubiquitination;GO:0070979|protein K11-linked ubiquitination;","GO:0000151|ubiquitin ligase complex;GO:0005634|nucleus;GO:0005680|anaphase-promoting complex;GO:0005829|cytosol;GO:0005886|plasma membrane;","GO:0004842|ubiquitin-protein transferase activity;GO:0005524|ATP binding;GO:0044389|ubiquitin-like protein ligase binding;GO:0061631|ubiquitin conjugating enzyme activity;","K06688","UBE2C, UBC11; ubiquitin-conjugating enzyme E2 C [EC:2.3.2.23]"]
["ENSRNOG00000031287",131,2.85167404726603,11.0217201926832,337,7.23932331096867,27.9799845968939,0.393914448184033,-1.34404576110073,{"v":1.30939918699298e-21,"d":"1.31E-21"},{"v":2.1798725995481e-20,"d":"2.18E-20"},"down","yes","Cacna2d3","protein_coding","chr16:4098445-4912351:-","gi|6753236|ref|NP_033915.1|",5128,0,"voltage-dependent calcium channel subunit alpha-2/delta-3 precursor [Mus musculus]","gi|6753235|ref|NM_009785.1|",2509,0,"Mus musculus calcium channel, voltage-dependent, alpha2/delta subunit 3 (Cacna2d3), mRNA","Q9Z1L5",1972,0,"Voltage-dependent calcium channel subunit alpha-2/delta-3",".",".",".",".","pfam08399","VWA_N","VWA N-terminal. This domain is found at the N-terminus of proteins containing von Willebrand factor type A (VWA, pfam00092) and Cache (pfam02743) domains. It has been found in vertebrates, Drosophila and C. elegans but has not yet been identified in other eukaryotes. It is probably involved in the function of some voltage-dependent calcium channel subunits.","GO:0006816|calcium ion transport;GO:0034765|regulation of ion transmembrane transport;GO:0070588|calcium ion transmembrane transport;GO:1990314|cellular response to insulin-like growth factor stimulus;","GO:0005891|voltage-gated calcium channel complex;GO:0016021|integral component of membrane;","GO:0005244|voltage-gated ion channel activity;GO:0005245|voltage-gated calcium channel activity;GO:0005246|calcium channel regulator activity;GO:0005262|calcium channel activity;GO:0046872|metal ion binding;","K04860","CACNA2D3; voltage-dependent calcium channel alpha-2/delta-3"]
["ENSRNOG00000002659",122,1.39311926911852,10.2645027748652,315,3.54959257130102,26.1533980653459,0.392473006728179,-1.34933466228071,{"v":2.04633045163406e-20,"d":"2.05E-20"},{"v":3.21651339727737e-19,"d":"3.22E-19"},"down","yes","Ciita","protein_coding","chr10:5140178-5187440:-","gi|399154121|ref|NP_001257732.1|",5282,0,"MHC class II transactivator isoform 2 [Rattus norvegicus]","gi|399154120|ref|NM_001270803.1|",4849,0,"Rattus norvegicus class II, major histocompatibility complex, transactivator (Ciita), transcript variant 2, mRNA","P79621",1878,0,"MHC class II transactivator",".",".",".",".","pfam05729","NACHT","NACHT domain. This NTPase domain is found in apoptosis proteins as well as those involved in MHC transcription activation. This family is closely related to pfam00931.","GO:0000122|negative regulation of transcription by RNA polymerase II;GO:0006954|inflammatory response;GO:0007568|aging;GO:0034341|response to interferon-gamma;GO:0045345|positive regulation of MHC class I biosynthetic process;GO:0045348|positive regulation of MHC class II biosynthetic process;GO:0045892|negative regulation of transcription, DNA-templated;GO:0045893|positive regulation of transcription, DNA-templated;GO:0045944|positive regulation of transcription by RNA polymerase II;GO:0046597|negative regulation of viral entry into host cell;GO:0046677|response to antibiotic;GO:0071257|cellular response to electrical stimulus;GO:0071346|cellular response to interferon-gamma;GO:0071360|cellular response to exogenous dsRNA;","GO:0005654|nucleoplasm;GO:0005829|cytosol;GO:0009986|cell surface;GO:0016605|PML body;","GO:0000976|transcription regulatory region sequence-specific DNA binding;GO:0003674|molecular_function;GO:0005524|ATP binding;GO:0008022|protein C-terminus binding;GO:0044877|protein-containing complex binding;","K08060","CIITA; MHC class II transactivator [EC:2.7.11.1]"]
["ENSRNOG00000037076",111,9.16488206060303,9.33901481975449,287,23.3843489407738,23.8286515706485,0.391923764215765,-1.3513550417819,{"v":8.83881265926231e-19,"d":"8.84E-19"},{"v":1.24243508619654E-17,"d":"1.24E-17"},"down","yes","ENSRNOG00000037076","protein_coding","chr4:162098942-162109157:-","gi|396578136|ref|NP_001094489.2|",1081,{"v":6e-145,"d":"6.00E-145"},"C-type lectin domain family 2 member D3 [Rattus norvegicus]","gi|672051243|ref|XM_008763332.1|",877,0,"PREDICTED: Rattus norvegicus similar to osteoclast inhibitory lectin (LOC689757), transcript variant X1, mRNA","A4KWA6",413,{"v":1e-143,"d":"1.00E-143"},"C-type lectin domain family 2 member D3",".",".",".",".","pfam00059","Lectin_C","Lectin C-type domain. This family includes both long and short form C-type",".","GO:0009897|external side of plasma membrane;GO:0016021|integral component of membrane;","GO:0030246|carbohydrate binding;GO:0046703|natural killer cell lectin-like receptor binding;",".","."]
["ENSRNOG00000018815",162,6.21519084392283,13.6299135207227,420,15.9011388146198,34.8711974204612,0.390864510798966,-1.35525949623782,{"v":7.49104823969195e-27,"d":"7.49E-27"},{"v":1.64468599661594e-25,"d":"1.64E-25"},"down","yes","Plk1","protein_coding","chr1:176716420-176726400:+","gi|53734301|gb|AAH83926.1|",2887,0,"Plk1 protein [Rattus norvegicus]","gi|53734300|gb|BC083926.1|",2175,0,"Rattus norvegicus polo-like kinase 1 (Drosophila), mRNA (cDNA clone MGC:95329 IMAGE:7135428), complete cds","Q62673",1113,0,"Serine/threonine-protein kinase PLK1",".",".",".",".","pfam00069","Pkinase","Protein kinase domain.","GO:0000070|mitotic sister chromatid segregation;GO:0000086|G2/M transition of mitotic cell cycle;GO:0000122|negative regulation of transcription by RNA polymerase II;GO:0000132|establishment of mitotic spindle orientation;GO:0000278|mitotic cell cycle;GO:0000281|mitotic cytokinesis;GO:0001578|microtubule bundle formation;GO:0006468|protein phosphorylation;GO:0007094|mitotic spindle assembly checkpoint;GO:0007095|mitotic G2 DNA damage checkpoint;GO:0007098|centrosome cycle;GO:0007346|regulation of mitotic cell cycle;GO:0010800|positive regulation of peptidyl-threonine phosphorylation;GO:0016321|female meiosis chromosome segregation;GO:0016567|protein ubiquitination;GO:0018105|peptidyl-serine phosphorylation;GO:0030071|regulation of mitotic metaphase/anaphase transition;GO:0031648|protein destabilization;GO:0032436|positive regulation of proteasomal ubiquitin-dependent protein catabolic process;GO:0032465|regulation of cytokinesis;GO:0033365|protein localization to organelle;GO:0040038|polar body extrusion after meiotic divisions;GO:0043066|negative regulation of apoptotic process;GO:0043393|regulation of protein binding;GO:0045143|homologous chromosome segregation;GO:0045184|establishment of protein localization;GO:0045736|negative regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0045862|positive regulation of proteolysis;GO:0046677|response to antibiotic;GO:0051081|nuclear envelope disassembly;GO:0051443|positive regulation of ubiquitin-protein transferase activity;GO:0070194|synaptonemal complex disassembly;GO:0071168|protein localization to chromatin;GO:0090435|protein localization to nuclear envelope;GO:1901673|regulation of mitotic spindle assembly;GO:1904668|positive regulation of ubiquitin protein ligase activity;GO:1904776|regulation of protein localization to cell cortex;","GO:0000775|chromosome, centromeric region;GO:0000776|kinetochore;GO:0000779|condensed chromosome, centromeric region;GO:0000785|chromatin;GO:0000795|synaptonemal complex;GO:0000922|spindle pole;GO:0000940|condensed chromosome outer kinetochore;GO:0005634|nucleus;GO:0005737|cytoplasm;GO:0005813|centrosome;GO:0005814|centriole;GO:0005819|spindle;GO:0005876|spindle microtubule;GO:0015630|microtubule cytoskeleton;GO:0030496|midbody;GO:0034451|centriolar satellite;GO:0051233|spindle midzone;GO:0097431|mitotic spindle pole;","GO:0000287|magnesium ion binding;GO:0004672|protein kinase activity;GO:0004674|protein serine/threonine kinase activity;GO:0005524|ATP binding;GO:0008017|microtubule binding;GO:0010997|anaphase-promoting complex binding;GO:0019901|protein kinase binding;GO:0042802|identical protein binding;","K06631","PLK1; polo-like kinase 1 [EC:2.7.11.21]"]
["ENSRNOG00000018378",116,1.59134047986086,9.75969116298667,302,4.08838276186567,25.0740514785221,0.389234710287908,-1.36128772565382,{"v":6.96523476830062e-20,"d":"6.97E-20"},{"v":1.06170290504787E-18,"d":"1.06E-18"},"down","yes","Cacnb2","protein_coding","chr17:77564460-77909106:+","gi|149021129|gb|EDL78736.1|",2658,0,"calcium channel, voltage-dependent, beta 2 subunit, isoform CRA_a [Rattus norvegicus]","gi|16758715|ref|NM_053851.1|",3479,0,"Rattus norvegicus calcium voltage-gated channel auxiliary subunit beta 2 (Cacnb2), mRNA","Q8VGC3",1028,0,"Voltage-dependent L-type calcium channel subunit beta-2",".",".",".",".","pfam00625","Guanylate_kin","Guanylate kinase.","GO:0006816|calcium ion transport;GO:0007268|chemical synaptic transmission;GO:0007528|neuromuscular junction development;GO:0007601|visual perception;GO:0034765|regulation of ion transmembrane transport;GO:0051928|positive regulation of calcium ion transport;GO:0070509|calcium ion import;GO:0070588|calcium ion transmembrane transport;GO:0072659|protein localization to plasma membrane;GO:0086045|membrane depolarization during AV node cell action potential;GO:0086091|regulation of heart rate by cardiac conduction;GO:0098912|membrane depolarization during atrial cardiac muscle cell action potential;GO:0099703|induction of synaptic vesicle exocytosis by positive regulation of presynaptic cytosolic calcium ion concentration;GO:1901385|regulation of voltage-gated calcium channel activity;GO:1901843|positive regulation of high voltage-gated calcium channel activity;GO:1904879|positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel;","GO:0005891|voltage-gated calcium channel complex;GO:0042383|sarcolemma;GO:0098684|photoreceptor ribbon synapse;GO:0098793|presynapse;GO:1990454|L-type voltage-gated calcium channel complex;","GO:0005245|voltage-gated calcium channel activity;GO:0005246|calcium channel regulator activity;GO:0005515|protein binding;GO:0008331|high voltage-gated calcium channel activity;GO:0019901|protein kinase binding;GO:0019904|protein domain specific binding;GO:0042802|identical protein binding;GO:0051015|actin filament binding;GO:0051219|phosphoprotein binding;GO:0086007|voltage-gated calcium channel activity involved in cardiac muscle cell action potential;GO:0086056|voltage-gated calcium channel activity involved in AV node cell action potential;GO:0099635|voltage-gated calcium channel activity involved in positive regulation of presynaptic cytosolic calcium levels;","K04863","CACNB2; voltage-dependent calcium channel beta-2"]
["ENSRNOG00000008054",420,7.90002522501754,35.3368128315034,1094,20.3065429497538,90.8311666142491,0.389038412129785,-1.36201548658275,{"v":1.14813083716536E-67,"d":"1.15E-67"},{"v":7.47654475021022e-66,"d":"7.48E-66"},"down","yes","Igsf9","protein_coding","chr13:84948619-84965607:+","gi|158635931|ref|NP_001100667.1|",4963,0,"protein turtle homolog A precursor [Rattus norvegicus]","gi|672074789|ref|XM_006250290.2|",3566,0,"PREDICTED: Rattus norvegicus immunoglobulin superfamily, member 9 (Igsf9), transcript variant X5, mRNA","P0C5H6",1916,0,"Protein turtle homolog A",".",".",".",".","pfam07679","I-set","Immunoglobulin I-set domain.","GO:0007156|homophilic cell adhesion via plasma membrane adhesion molecules;GO:0016358|dendrite development;GO:0050807|regulation of synapse organization;GO:0098609|cell-cell adhesion;","GO:0005886|plasma membrane;GO:0016021|integral component of membrane;GO:0030424|axon;GO:0030425|dendrite;GO:0043005|neuron projection;GO:0060077|inhibitory synapse;","GO:0098632|cell-cell adhesion mediator activity;","K22655","IGSF9; immunoglobulin superfamily member 9"]
["ENSRNOG00000048818",104,3.07775868421717,8.75006793922943,271,7.91425430962012,22.50022500225,0.388888019491112,-1.3625733046691,{"v":5.00569911822192E-18,"d":"5.01E-18"},{"v":6.64593924884266e-17,"d":"6.65E-17"},"down","yes","Catsperd","protein_coding","chr9:1460001-1498344:+","gi|564366897|ref|XP_006244402.1|",4059,0,"PREDICTED: cation channel sperm-associated protein subunit delta isoform X3 [Rattus norvegicus]","gi|672063991|ref|XM_006244344.2|",2273,0,"PREDICTED: Rattus norvegicus catsper channel auxiliary subunit delta (Catsperd), transcript variant X6, mRNA","B5DFM7",1420,0,"Cation channel sperm-associated protein subunit delta",".",".",".",".","pfam15020","CATSPERD","Cation channel sperm-associated protein subunit delta. The CATSPER (cation channel of sperm) complex is a tetrameric complex consisting of CATSPER1, CATSPER2, CATSPER3 and CATSPER4, it functions as an alkalinisation-activated calcium channel. This complex requires several auxiliary subunits, including CATSPERD. CATSPERD is essential for the cation channel function and may play a role in channel assembly or transport.","GO:0007283|spermatogenesis;GO:0030317|flagellated sperm motility;GO:0048240|sperm capacitation;","GO:0036128|CatSper complex;GO:0097228|sperm principal piece;",".","K16895","CATSPERD; cation channel sperm-associated protein subunit delta"]
["ENSRNOG00000027096",105,7.09574554849467,8.83420320787586,276,18.4059102850398,22.9153583048745,0.385514513469189,-1.37514292056836,{"v":1.44215721574714e-18,"d":"1.44E-18"},{"v":1.99784343145603e-17,"d":"2.00E-17"},"down","yes","Ctsw","protein_coding","chr1:202772572-202775964:-","gi|66730453|ref|NP_001019413.1|",1827,0,"cathepsin W precursor [Rattus norvegicus]","gi|66730452|ref|NM_001024242.1|",1245,0,"Rattus norvegicus cathepsin W (Ctsw), mRNA","P56203",611,0,"Cathepsin W","MA3430_1",57.8,{"v":3e-08,"d":"3.00E-08"},"COG4870","pfam00112","Peptidase_C1","Papain family cysteine protease.","GO:0051603|proteolysis involved in cellular protein catabolic process;","GO:0005615|extracellular space;GO:0005764|lysosome;","GO:0004197|cysteine-type endopeptidase activity;","K08569","CTSW; cathepsin W [EC:3.4.22.-]"]
["ENSRNOG00000008146",210,5.62329930482232,17.6684064157517,552,14.5864788700665,45.8307166097491,0.385514513469189,-1.37514292056836,{"v":1.64970267069574e-35,"d":"1.65E-35"},{"v":5.12721880202511e-34,"d":"5.13E-34"},"down","yes","Tox2","protein_coding","chr3:151853294-151980749:+","gi|564344383|ref|XP_006235640.1|",1713,0,"PREDICTED: TOX high mobility group box family member 2 isoform X1 [Rattus norvegicus]","gi|672048111|ref|XM_006235578.2|",2238,0,"PREDICTED: Rattus norvegicus TOX high mobility group box family member 2 (Tox2), transcript variant X1, mRNA","Q76IQ7",555,0,"TOX high mobility group box family member 2",".",".",".",".","pfam00505","HMG_box","HMG (high mobility group) box.","GO:0006357|regulation of transcription by RNA polymerase II;GO:0008585|female gonad development;GO:0034698|response to gonadotropin;GO:0045944|positive regulation of transcription by RNA polymerase II;","GO:0005634|nucleus;GO:0005654|nucleoplasm;","GO:0003677|DNA binding;GO:0003713|transcription coactivator activity;GO:0031490|chromatin DNA binding;GO:0061629|RNA polymerase II sequence-specific DNA-binding transcription factor binding;",".","."]
["ENSRNOG00000043451",1291,69.4048765639297,108.618631822549,3409,180.854879060326,283.03788572941,0.383760045206072,-1.38172358028907,{"v":2.76546732946663e-211,"d":"2.77E-211"},{"v":6.61813209235861e-209,"d":"6.62E-209"},"down","yes","Spp1","protein_coding","chr14:5308885-5315162:-","gi|145046230|ref|NP_037013.2|",1391,0,"osteopontin precursor [Rattus norvegicus]","gi|298910168|emb|FQ222192.1|",1489,0,"Rattus norvegicus TL0ADA27YG14 mRNA sequence","P08721",521,0,"Osteopontin",".",".",".",".","pfam00865","Osteopontin","Osteopontin.","GO:0001649|osteoblast differentiation;GO:0006710|androgen catabolic process;GO:0006874|cellular calcium ion homeostasis;GO:0006883|cellular sodium ion homeostasis;GO:0006954|inflammatory response;GO:0007155|cell adhesion;GO:0007165|signal transduction;GO:0010033|response to organic substance;GO:0010811|positive regulation of cell-substrate adhesion;GO:0030154|cell differentiation;GO:0030593|neutrophil chemotaxis;GO:0030643|cellular phosphate ion homeostasis;GO:0030644|cellular chloride ion homeostasis;GO:0031214|biomineral tissue development;GO:0033280|response to vitamin D;GO:0034418|urate biosynthetic process;GO:0045780|positive regulation of bone resorption;GO:0045893|positive regulation of transcription, DNA-templated;GO:0048545|response to steroid hormone;GO:0048685|negative regulation of collateral sprouting of intact axon in response to injury;GO:0071394|cellular response to testosterone stimulus;GO:0071498|cellular response to fluid shear stress;GO:0072044|collecting duct development;GO:1990830|cellular response to leukemia inhibitory factor;GO:2000866|positive regulation of estradiol secretion;","GO:0005615|extracellular space;GO:0005737|cytoplasm;GO:0005794|Golgi apparatus;GO:0031982|vesicle;GO:0042995|cell projection;GO:0045177|apical part of cell;GO:0048471|perinuclear region of cytoplasm;","GO:0005125|cytokine activity;GO:0005178|integrin binding;GO:0050840|extracellular matrix binding;","K06250","SPP1, BNSP, OPN; secreted phosphoprotein 1"]
["ENSRNOG00000021750",603,54.1446819570986,50.7335669938014,1600,141.774447000909,132.842656839852,0.381907199093156,-1.38870597933096,{"v":5.60476908045929e-101,"d":"5.60E-101"},{"v":5.61647442524121e-99,"d":"5.62E-99"},"down","yes","Id1","protein_coding","chr3:141211267-141212419:+","gi|564343661|ref|XP_006235329.1|",716,{"v":1E-91,"d":"1.00E-91"},"PREDICTED: DNA-binding protein inhibitor ID-1 isoform X1 [Rattus norvegicus]","gi|672047400|ref|XM_006235267.2|",935,0,"PREDICTED: Rattus norvegicus inhibitor of DNA binding 1 (Id1), transcript variant X1, mRNA","P41135",242,{"v":4E-78,"d":"4.00E-78"},"DNA-binding protein inhibitor ID-1",".",".",".",".","pfam00010","HLH","Helix-loop-helix DNA-binding domain.","GO:0000122|negative regulation of transcription by RNA polymerase II;GO:0001886|endothelial cell morphogenesis;GO:0007420|brain development;GO:0007507|heart development;GO:0007623|circadian rhythm;GO:0010628|positive regulation of gene expression;GO:0010629|negative regulation of gene expression;GO:0014070|response to organic cyclic compound;GO:0030154|cell differentiation;GO:0030182|neuron differentiation;GO:0030509|BMP signaling pathway;GO:0031648|protein destabilization;GO:0032091|negative regulation of protein binding;GO:0032233|positive regulation of actin filament bundle assembly;GO:0032922|circadian regulation of gene expression;GO:0032963|collagen metabolic process;GO:0036164|cell-abiotic substrate adhesion;GO:0043066|negative regulation of apoptotic process;GO:0043392|negative regulation of DNA binding;GO:0043408|regulation of MAPK cascade;GO:0043433|negative regulation of DNA-binding transcription factor activity;GO:0045602|negative regulation of endothelial cell differentiation;GO:0045668|negative regulation of osteoblast differentiation;GO:0045765|regulation of angiogenesis;GO:0045892|negative regulation of transcription, DNA-templated;GO:0046677|response to antibiotic;GO:0050679|positive regulation of epithelial cell proliferation;GO:0050774|negative regulation of dendrite morphogenesis;GO:0060425|lung morphogenesis;GO:0060426|lung vasculature development;GO:0071364|cellular response to epidermal growth factor stimulus;GO:0071560|cellular response to transforming growth factor beta stimulus;GO:0120163|negative regulation of cold-induced thermogenesis;GO:1901342|regulation of vasculature development;GO:1901653|cellular response to peptide;GO:1903351|cellular response to dopamine;GO:1990090|cellular response to nerve growth factor stimulus;","GO:0005634|nucleus;GO:0005654|nucleoplasm;GO:0005737|cytoplasm;GO:0005794|Golgi apparatus;GO:0005813|centrosome;","GO:0005515|protein binding;GO:0008022|protein C-terminus binding;GO:0042802|identical protein binding;GO:0043621|protein self-association;GO:0046983|protein dimerization activity;GO:0047485|protein N-terminus binding;GO:0070628|proteasome binding;GO:0140110|transcription regulator activity;","K04680","ID1; DNA-binding protein inhibitor ID1"]
["ENSRNOG00000028548",107,6.98949824935461,9.00247374516874,284,18.3071207989703,23.5795715890738,0.381791234465865,-1.38914411455985,{"v":2.4809131071436E-19,"d":"2.48E-19"},{"v":3.64242692837578E-18,"d":"3.64E-18"},"down","yes","Ccl9","protein_coding","chr10:68366487-68371369:-","gi|59891435|ref|NP_001012357.1|",623,{"v":1e-76,"d":"1.00E-76"},"C-C motif chemokine 9 precursor [Rattus norvegicus]","gi|59891434|ref|NM_001012357.1|",1288,0,"Rattus norvegicus chemokine (C-C motif) ligand 9 (Ccl9), mRNA","P51670",182,{"v":4e-54,"d":"4.00E-54"},"C-C motif chemokine 9",".",".",".",".","pfam00048","IL8","Small cytokines (intecrine/chemokine), interleukin-8 like. Includes a number of secreted growth factors and interferons involved in mitogenic, chemotactic, and inflammatory activity. Structure contains two highly conserved disulfide bonds.","GO:0002548|monocyte chemotaxis;GO:0006954|inflammatory response;GO:0007186|G protein-coupled receptor signaling pathway;GO:0030593|neutrophil chemotaxis;GO:0043547|positive regulation of GTPase activity;GO:0048247|lymphocyte chemotaxis;GO:0070098|chemokine-mediated signaling pathway;GO:0070374|positive regulation of ERK1 and ERK2 cascade;GO:0071346|cellular response to interferon-gamma;GO:0071347|cellular response to interleukin-1;GO:0071356|cellular response to tumor necrosis factor;","GO:0005615|extracellular space;","GO:0008009|chemokine activity;GO:0048020|CCR chemokine receptor binding;","K22671","CCL9; C-C motif chemokine 9"]
["ENSRNOG00000011358",241,4.74417401586131,20.2765997437912,642,12.4714824653698,53.3031160569908,0.380401770922958,-1.39440413234866,{"v":7.40268050418585e-42,"d":"7.40E-42"},{"v":2.88058562411023e-40,"d":"2.88E-40"},"down","yes","Hipk3","protein_coding","chr3:90800296-90867759:-","gi|149022796|gb|EDL79690.1|",6298,0,"homeodomain interacting protein kinase 3, isoform CRA_a [Rattus norvegicus]","gi|672046435|ref|XM_006234658.2|",4112,0,"PREDICTED: Rattus norvegicus homeodomain interacting protein kinase 3 (Hipk3), transcript variant X1, mRNA","O88850",2428,0,"Homeodomain-interacting protein kinase 3",".",".",".",".","pfam00069","Pkinase","Protein kinase domain.","GO:0006468|protein phosphorylation;GO:0006915|apoptotic process;GO:0009299|mRNA transcription;GO:0018105|peptidyl-serine phosphorylation;GO:0018107|peptidyl-threonine phosphorylation;GO:0018108|peptidyl-tyrosine phosphorylation;GO:0043066|negative regulation of apoptotic process;GO:0043508|negative regulation of JUN kinase activity;","GO:0005634|nucleus;GO:0005737|cytoplasm;GO:0005829|cytosol;GO:0005886|plasma membrane;GO:0016604|nuclear body;GO:0016605|PML body;","GO:0003677|DNA binding;GO:0004672|protein kinase activity;GO:0004674|protein serine/threonine kinase activity;GO:0004713|protein tyrosine kinase activity;GO:0005524|ATP binding;","K08826","HIPK; homeodomain interacting protein kinase [EC:2.7.11.1]"]
["ENSRNOG00000020013",150,6.43892362090077,12.6202902969655,400,16.9442164336546,33.2106642099631,0.380007163276772,-1.39590148073516,{"v":9.3259889590448e-27,"d":"9.33E-27"},{"v":2.03356129316274e-25,"d":"2.03E-25"},"down","yes","Psrc1","protein_coding","chr2:196022361-196026874:+","gi|112983728|ref|NP_001037767.1|",1387,0,"proline/serine-rich coiled-coil protein 1 [Rattus norvegicus]","gi|672043837|ref|XM_006233177.2|",1643,0,"PREDICTED: Rattus norvegicus proline/serine-rich coiled-coil 1 (Psrc1), transcript variant X3, mRNA","Q3KR66",538,0,"Proline/serine-rich coiled-coil protein 1",".",".",".",".","pfam15259","GTSE1_N","G-2 and S-phase expressed 1. This family is the N-terminus of GTSE1 proteins. GTSE-1 (G2 and S phase-expressed-1) protein is specifically expressed during S and G2 phases of the cell cycle. It is mainly localized to the microtubules and when overexpressed delays the G2 to M transition. the full protein negatively regulates p53 transactivation function, protein levels, and p53-dependent apoptosis. This domain family is found in eukaryotes, and is approximately 140 amino acids in length. There is a conserved FDFD sequence motif.","GO:0001578|microtubule bundle formation;GO:0007080|mitotic metaphase plate congression;GO:0009987|cellular process;GO:0030308|negative regulation of cell growth;GO:0031116|positive regulation of microtubule polymerization;GO:0045737|positive regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0045893|positive regulation of transcription, DNA-templated;GO:0051301|cell division;GO:0060236|regulation of mitotic spindle organization;","GO:0000922|spindle pole;GO:0005654|nucleoplasm;GO:0005737|cytoplasm;GO:0005819|spindle;GO:0005829|cytosol;GO:0005876|spindle microtubule;GO:0015630|microtubule cytoskeleton;GO:0030496|midbody;","GO:0008017|microtubule binding;","K21443","PSRC1; proline/serine-rich coiled-coil protein 1"]
["ENSRNOG00000047414",115,4.01975733042801,9.67555589434023,308,10.6241011390409,25.5722114416716,0.378362110621894,-1.40216047120684,{"v":4.17210097551762e-21,"d":"4.17E-21"},{"v":6.75762705981404e-20,"d":"6.76E-20"},"down","yes","AABR07058479.1","protein_coding","chr7:109157933-109175591:-","gi|672022243|ref|XP_008774771.1|",1432,0,"PREDICTED: LOW QUALITY PROTEIN: apolipoprotein L2-like isoform X1 [Rattus norvegicus]","gi|672059741|ref|XM_008765649.1|",1287,0,"PREDICTED: Rattus norvegicus similar to RIKEN cDNA 2210421G13 (RGD1565356), transcript variant X2, mRNA","O95236",201,{"v":2E-55,"d":"2.00E-55"},"Apolipoprotein L3",".",".",".",".","pfam05461","ApoL","Apolipoprotein L. Apo L belongs to the high density lipoprotein family that plays a central role in cholesterol transport. The cholesterol content of membranes is important in cellular processes such as modulating gene transcription and signal transduction both in the adult brain and during neurodevelopment. There are six apo L genes located in close proximity to each other on chromosome 22q12 in humans. 22q12 is a confirmed high-susceptibility locus for schizophrenia and close to the region associated with velocardiofacial syndrome that includes symptoms of schizophrenia.",".",".",".",".","."]
["ENSRNOG00000019328",237,10.5502955921722,19.9400586692055,640,28.1148480084343,53.137062735941,0.375257073735812,-1.41404882744542,{"v":1.37647339815339E-42,"d":"1.38E-42"},{"v":5.55963610709163e-41,"d":"5.56E-41"},"down","yes","Phgdh","protein_coding","chr2:185906966-185935944:-","gi|13928850|ref|NP_113808.1|",2480,0,"D-3-phosphoglycerate dehydrogenase [Rattus norvegicus]","gi|564338012|ref|XM_006233010.1|",1546,0,"PREDICTED: Rattus norvegicus phosphoglycerate dehydrogenase (Phgdh), transcript variant X1, mRNA","O08651",959,0,"D-3-phosphoglycerate dehydrogenase","MJ1018",327,{"v":1e-102,"d":"1.00E-102"},"COG0111","pfam00389","2-Hacid_dh","D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain. This family represents the largest portion of the catalytic domain of 2-hydroxyacid dehydrogenases as the NAD binding domain is inserted within the structural domain.","GO:0006541|glutamine metabolic process;GO:0006544|glycine metabolic process;GO:0006563|L-serine metabolic process;GO:0006564|L-serine biosynthetic process;GO:0006566|threonine metabolic process;GO:0009070|serine family amino acid biosynthetic process;GO:0009448|gamma-aminobutyric acid metabolic process;GO:0010468|regulation of gene expression;GO:0019530|taurine metabolic process;GO:0021510|spinal cord development;GO:0021782|glial cell development;GO:0021915|neural tube development;GO:0022008|neurogenesis;GO:0031175|neuron projection development;GO:0070314|G1 to G0 transition;","GO:0005575|cellular_component;","GO:0004617|phosphoglycerate dehydrogenase activity;GO:0051287|NAD binding;","K00058","serA, PHGDH; D-3-phosphoglycerate dehydrogenase / 2-oxoglutarate reductase [EC:1.1.1.95 1.1.1.399]"]
["ENSRNOG00000014426",151,7.12530878609756,12.7044255656119,410,19.0919410068492,34.0409308152122,0.373210287185643,-1.42193934163668,{"v":4.10104106668211e-28,"d":"4.10E-28"},{"v":9.43686359927654e-27,"d":"9.44E-27"},"down","yes","Lox","protein_coding","chr18:45967343-46041477:-","gi|8393733|ref|NP_058757.1|",1816,0,"protein-lysine 6-oxidase precursor [Rattus norvegicus]","gi|148747289|ref|NM_017061.2|",1783,0,"Rattus norvegicus lysyl oxidase (Lox), mRNA","P16636",704,0,"Protein-lysine 6-oxidase",".",".",".",".","pfam01186","Lysyl_oxidase","Lysyl oxidase.","GO:0001568|blood vessel development;GO:0001649|osteoblast differentiation;GO:0001932|regulation of protein phosphorylation;GO:0007507|heart development;GO:0009410|response to xenobiotic stimulus;GO:0009725|response to hormone;GO:0010468|regulation of gene expression;GO:0016202|regulation of striated muscle tissue development;GO:0017015|regulation of transforming growth factor beta receptor signaling pathway;GO:0018057|peptidyl-lysine oxidation;GO:0018158|protein oxidation;GO:0030199|collagen fibril organization;GO:0030282|bone mineralization;GO:0030324|lung development;GO:0035791|platelet-derived growth factor receptor-beta signaling pathway;GO:0035904|aorta development;GO:0035905|ascending aorta development;GO:0035906|descending aorta development;GO:0042060|wound healing;GO:0042981|regulation of apoptotic process;GO:0043491|protein kinase B signaling;GO:0045652|regulation of megakaryocyte differentiation;GO:0046716|muscle cell cellular homeostasis;GO:0048251|elastic fiber assembly;GO:0048514|blood vessel morphogenesis;GO:0048545|response to steroid hormone;GO:0055001|muscle cell development;GO:0060326|cell chemotaxis;GO:0061448|connective tissue development;GO:0071310|cellular response to organic substance;GO:0071897|DNA biosynthetic process;GO:1900120|regulation of receptor binding;GO:1903010|regulation of bone development;GO:1990869|cellular response to chemokine;GO:2000586|regulation of platelet-derived growth factor receptor-beta signaling pathway;","GO:0005576|extracellular region;GO:0005581|collagen trimer;GO:0005615|extracellular space;GO:0005634|nucleus;GO:0031012|extracellular matrix;","GO:0004720|protein-lysine 6-oxidase activity;GO:0005507|copper ion binding;GO:0005518|collagen binding;","K00277","LOX; protein-lysine 6-oxidase [EC:1.4.3.13]"]
["ENSRNOG00000067835",246,12.7839877004468,20.6972760870234,669,34.3081135831768,55.5448358911633,0.372622868624159,-1.42421187675854,{"v":6.68192359311868e-45,"d":"6.68E-45"},{"v":2.85548824780598e-43,"d":"2.86E-43"},"down","yes","ENSRNOG00000067835","lncRNA","chr12:35662951-35668551:+","gi|149027698|gb|EDL83221.1|",199,{"v":3e-15,"d":"3.00E-15"},"rCG29124 [Rattus norvegicus]","gi|241982901|gb|AC136178.3|",611,0,"Rattus norvegicus CH230-435P16 (Children's Hospital Oakland Research Institute Rat (BN/SsNHsd/MCW) BAC library) complete sequence",".",".",".",".",".",".",".",".","pfam00429","TLV_coat","ENV polyprotein (coat polyprotein).",".",".",".",".","."]
["ENSRNOG00000007564",209,3.93296156276119,17.5842711471053,579,10.7520546732099,48.0724364439216,0.365786975819668,-1.45092438736467,{"v":3.74681881254607e-40,"d":"3.75E-40"},{"v":1.39558553367073e-38,"d":"1.40E-38"},"down","yes","Evc","protein_coding","chr14:73456222-73498099:+","gi|564383995|ref|XP_006251152.1|",4074,0,"PREDICTED: Ellis van Creveld syndrome protein isoform X1 [Rattus norvegicus]","gi|672076396|ref|XM_006251090.2|",4031,0,"PREDICTED: Rattus norvegicus Ellis van Creveld syndrome (Evc), transcript variant X1, mRNA","P57680",1377,0,"Ellis-van Creveld syndrome protein homolog",".",".",".",".","pfam13514","AAA_27","AAA domain. This domain is found in a number of double-strand DNA break proteins. This domain contains a P-loop motif.","GO:0003416|endochondral bone growth;GO:0007224|smoothened signaling pathway;GO:0045880|positive regulation of smoothened signaling pathway;GO:0051216|cartilage development;","GO:0005575|cellular_component;GO:0005737|cytoplasm;GO:0005929|cilium;GO:0016021|integral component of membrane;GO:0036064|ciliary basal body;GO:0060170|ciliary membrane;GO:0098797|plasma membrane protein complex;","GO:0003674|molecular_function;","K19605","EVC1; ellis van creveld syndrome protein 1"]
["ENSRNOG00000000479",146,4.97116520533378,12.2837492223797,407,13.6753746797399,33.7918508336374,0.36351217584543,-1.45992440684255,{"v":5.58118471715568E-29,"d":"5.58E-29"},{"v":1.36291013008675E-27,"d":"1.36E-27"},"down","yes","Kifc1","protein_coding","chr20:4999047-5017105:+","gi|54312052|ref|NP_001005878.1|",3052,0,"kinesin-like protein KIFC1 [Rattus norvegicus]","gi|54312051|ref|NM_001005878.1|",2217,0,"Rattus norvegicus kinesin family member C1 (Kifc1), mRNA","Q5XI63",1180,0,"Kinesin-like protein KIFC1","SPAC664.10",308,{"v":4e-91,"d":"4.00E-91"},"COG5059","pfam00225","Kinesin","Kinesin motor domain.","GO:0007018|microtubule-based movement;GO:0007080|mitotic metaphase plate congression;GO:0007283|spermatogenesis;GO:0051301|cell division;GO:0090307|mitotic spindle assembly;","GO:0005634|nucleus;GO:0005769|early endosome;GO:0005815|microtubule organizing center;GO:0005871|kinesin complex;GO:0005874|microtubule;GO:0072686|mitotic spindle;","GO:0003777|microtubule motor activity;GO:0005515|protein binding;GO:0005524|ATP binding;GO:0008017|microtubule binding;GO:0016887|ATPase activity;","K10405","KIFC1; kinesin family member C1"]
["ENSRNOG00000003189",449,34.3112948430973,37.7767356222501,1272,95.9218094347708,105.609912187682,0.357700663126354,-1.48317530199953,{"v":7.43426454203205E-89,"d":"7.43E-89"},{"v":6.41123834326165e-87,"d":"6.41E-87"},"down","yes","Cited1","protein_coding","chrX:67350373-67355162:-","gi|564399592|ref|XP_006257159.1|",848,{"v":2e-110,"d":"2.00E-110"},"PREDICTED: cbp/p300-interacting transactivator 1 isoform X2 [Rattus norvegicus]","gi|67972659|ref|NM_172055.2|",834,0,"Rattus norvegicus Cbp/p300-interacting transactivator with Glu/Asp-rich carboxy-terminal domain 1 (Cited1), mRNA","P97769",263,{"v":1e-85,"d":"1.00E-85"},"Cbp/p300-interacting transactivator 1",".",".",".",".","pfam04487","CITED","CITED. CITED, CBP/p300-interacting transactivator with ED-rich tail, are characterized by a conserved 32-amino acid sequence at the C-terminus. CITED proteins do not bind DNA directly and are thought to function as transcriptional co-activators.","GO:0000578|embryonic axis specification;GO:0001570|vasculogenesis;GO:0001658|branching involved in ureteric bud morphogenesis;GO:0001890|placenta development;GO:0003340|negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis;GO:0006913|nucleocytoplasmic transport;GO:0007179|transforming growth factor beta receptor signaling pathway;GO:0007420|brain development;GO:0010628|positive regulation of gene expression;GO:0030318|melanocyte differentiation;GO:0032496|response to lipopolysaccharide;GO:0032868|response to insulin;GO:0034097|response to cytokine;GO:0034341|response to interferon-gamma;GO:0042438|melanin biosynthetic process;GO:0042981|regulation of apoptotic process;GO:0043473|pigmentation;GO:0043524|negative regulation of neuron apoptotic process;GO:0043627|response to estrogen;GO:0045668|negative regulation of osteoblast differentiation;GO:0045892|negative regulation of transcription, DNA-templated;GO:0045893|positive regulation of transcription, DNA-templated;GO:0045944|positive regulation of transcription by RNA polymerase II;GO:0051591|response to cAMP;GO:0060395|SMAD protein signal transduction;GO:0060711|labyrinthine layer development;GO:0060712|spongiotrophoblast layer development;GO:0070555|response to interleukin-1;GO:0070669|response to interleukin-2;GO:0070670|response to interleukin-4;GO:0070741|response to interleukin-6;GO:0071104|response to interleukin-9;GO:0071105|response to interleukin-11;GO:0071107|response to parathyroid hormone;GO:0071559|response to transforming growth factor beta;","GO:0005634|nucleus;GO:0005654|nucleoplasm;GO:0005737|cytoplasm;GO:0005829|cytosol;","GO:0003682|chromatin binding;GO:0003713|transcription coactivator activity;GO:0008022|protein C-terminus binding;GO:0042803|protein homodimerization activity;GO:0050693|LBD domain binding;GO:0070410|co-SMAD binding;","K22527","CITED1; Cbp/p300-interacting transactivator 1"]
["ENSRNOG00000015529",140,6.19617970042144,11.7789376105011,402,17.5574526728106,33.3767175310129,0.352908808349904,-1.50263265569028,{"v":7.95555229201582e-30,"d":"7.96E-30"},{"v":1.99358089021816e-28,"d":"1.99E-28"},"down","yes","Cdca3","protein_coding","chr4:157634928-157638799:+","gi|56090612|ref|NP_001007649.1|",1206,{"v":4e-161,"d":"4.00E-161"},"cell division cycle-associated protein 3 [Rattus norvegicus]","gi|56090611|ref|NM_001007648.1|",1492,0,"Rattus norvegicus cell division cycle associated 3 (Cdca3), mRNA","Q68FW2",469,{"v":1e-162,"d":"1.00E-162"},"Cell division cycle-associated protein 3",".",".",".",".","pfam15402","Spc7_N","N-terminus of kinetochore NMS complex subunit Spc7.","GO:0016567|protein ubiquitination;GO:0051301|cell division;","GO:0005829|cytosol;GO:0005912|adherens junction;",".",".","."]
["ENSRNOG00000028243",111,4.66717382296576,9.33901481975449,319,13.2361342865795,26.4855047074456,0.352608527680014,-1.50386072887108,{"v":4.92536962864031e-24,"d":"4.93E-24"},{"v":9.52490207320756E-23,"d":"9.52E-23"},"down","yes","Derl3","protein_coding","chr20:12763543-12767027:-","gi|199560022|ref|NP_001103047.2|",869,{"v":1e-111,"d":"1.00E-111"},"derlin-3 [Rattus norvegicus]","gi|157818726|ref|NM_001109577.1|",1357,0,"Rattus norvegicus derlin 3 (Derl3), mRNA","Q9D8K3",333,{"v":7e-111,"d":"7.00E-111"},"Derlin-3","ECU11g1920",98.6,{"v":5e-22,"d":"5.00E-22"},"COG5291","pfam04511","DER1","Der1-like family. The endoplasmic reticulum (ER) of the yeast Saccharomyces cerevisiae contains of proteolytic system able to selectively degrade misfolded lumenal secretory proteins. For examination of the components involved in this degradation process, mutants were isolated. They could be divided into four complementation groups. The mutations led to stabilisation of two different substrates for this process. The mutant classes were called 'der' for 'degradation in the ER'. DER1 was cloned by complementation of the der1-2 mutation. The DER1 gene codes for a novel, hydrophobic protein, that is localized to the ER. Deletion of DER1 abolished degradation of the substrate proteins. The function of the Der1 protein seems to be specifically required for the degradation process associated with the ER. Interestingly this family seems distantly related to the Rhomboid family of membrane peptidases. Suggesting that this family may also mediate degradation of misfolded proteins (Bateman A pers. obs.).","GO:0018279|protein N-linked glycosylation via asparagine;GO:0030433|ubiquitin-dependent ERAD pathway;GO:0030968|endoplasmic reticulum unfolded protein response;GO:1904153|negative regulation of retrograde protein transport, ER to cytosol;","GO:0000839|Hrd1p ubiquitin ligase ERAD-L complex;GO:0030176|integral component of endoplasmic reticulum membrane;","GO:0005047|signal recognition particle binding;GO:0044877|protein-containing complex binding;GO:0051787|misfolded protein binding;GO:1990381|ubiquitin-specific protease binding;","K13989","DERL2_3; Derlin-2/3"]
["ENSRNOG00000019377",1641,78.4465771868198,138.065975848802,4729,223.086975921755,392.633077622289,0.351641223620037,-1.50782388440041,0,0,"down","yes","Amh","protein_coding","chr7:8906836-8909282:-","gi|25742760|ref|NP_037034.1|",2364,0,"muellerian-inhibiting factor precursor [Rattus norvegicus]","gi|25742759|ref|NM_012902.1|",1662,0,"Rattus norvegicus anti-Mullerian hormone (Amh), mRNA","P49000",915,0,"Muellerian-inhibiting factor",".",".",".",".","pfam04709","AMH_N","Anti-Mullerian hormone, N terminal region. Anti-Mullerian hormone, AMH is a signalling molecule involved in male and female sexual differentiation. Defects in synthesis or action of AMH cause persistent Mullerian duct syndrome (PMDS), a rare form of male pseudohermaphroditism. This family represents the N terminal part of the protein, which is not thought to be essential for activity. AMH contains a TGF-beta domain (pfam00019), at the C terminus.","GO:0001546|preantral ovarian follicle growth;GO:0001655|urogenital system development;GO:0001880|Mullerian duct regression;GO:0007165|signal transduction;GO:0007506|gonadal mesoderm development;GO:0007568|aging;GO:0009410|response to xenobiotic stimulus;GO:0010628|positive regulation of gene expression;GO:0014070|response to organic cyclic compound;GO:0051092|positive regulation of NF-kappaB transcription factor activity;GO:2000355|negative regulation of ovarian follicle development;","GO:0005615|extracellular space;GO:0005737|cytoplasm;","GO:0005102|signaling receptor binding;GO:0005160|transforming growth factor beta receptor binding;GO:0005515|protein binding;GO:0008083|growth factor activity;","K04665","AMH; anti-mullerian hormone"]
["ENSRNOG00000010263",300,13.6583228322137,25.240580593931,865,38.862587312795,71.8180613540452,0.351451711701061,-1.50860161348452,{"v":1.57276371884721E-62,"d":"1.57E-62"},{"v":9.29341557045841e-61,"d":"9.29E-61"},"down","yes","Cldn11","protein_coding","chr2:112207745-112221050:-","gi|148703035|gb|EDL34982.1|",1012,{"v":9e-131,"d":"9.00E-131"},"claudin 11, partial [Mus musculus]","gi|61889102|ref|NM_053457.2|",1845,0,"Rattus norvegicus claudin 11 (Cldn11), mRNA","Q60771",352,{"v":3e-116,"d":"3.00E-116"},"Claudin-11",".",".",".",".","pfam00822","PMP22_Claudin","PMP-22/EMP/MP20/Claudin family.","GO:0007155|cell adhesion;GO:0007283|spermatogenesis;GO:0008366|axon ensheathment;GO:0016338|calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules;GO:0070830|bicellular tight junction assembly;GO:0120192|tight junction assembly;","GO:0005811|lipid droplet;GO:0005883|neurofilament;GO:0005886|plasma membrane;GO:0005923|bicellular tight junction;GO:0016021|integral component of membrane;GO:0030054|cell junction;GO:0030424|axon;GO:0045178|basal part of cell;GO:0070160|tight junction;","GO:0005198|structural molecule activity;GO:0042802|identical protein binding;","K06087","CLDN; claudin"]
["ENSRNOG00000020097",5729,223.463585570438,482.010954075436,17043,656.014545816413,1415.023375326,0.340638156570655,-1.55368804738697,0,0,"down","yes","Inha","protein_coding","chr9:76993589-76997248:+","gi|6981102|ref|NP_036722.1|",1521,0,"inhibin alpha chain precursor [Rattus norvegicus]","gi|126506324|ref|NM_012590.2|",1281,0,"Rattus norvegicus inhibin alpha (Inha), mRNA","P17490",590,0,"Inhibin alpha chain",".",".",".",".","pfam00019","TGF_beta","Transforming growth factor beta like domain.","GO:0001541|ovarian follicle development;GO:0008584|male gonad development;GO:0010862|positive regulation of pathway-restricted SMAD protein phosphorylation;GO:0042127|regulation of cell proliferation;GO:0042541|hemoglobin biosynthetic process;GO:0046882|negative regulation of follicle-stimulating hormone secretion;GO:0051726|regulation of cell cycle;GO:0060395|SMAD protein signal transduction;","GO:0001750|photoreceptor outer segment;GO:0001917|photoreceptor inner segment;GO:0005615|extracellular space;GO:0005737|cytoplasm;GO:0034673|inhibin-betaglycan-ActRII complex;GO:0043025|neuronal cell body;GO:0043512|inhibin A complex;GO:0043513|inhibin B complex;","GO:0005102|signaling receptor binding;GO:0005125|cytokine activity;GO:0005179|hormone activity;GO:0008083|growth factor activity;GO:0034711|inhibin binding;GO:0044877|protein-containing complex binding;","K05500","INHA; inhibin, alpha"]
["ENSRNOG00000021724",147,14.5333542785266,12.3678844910262,440,42.9280030916092,36.5317306309594,0.338551836373851,-1.56255135014461,{"v":2.62720319987854e-34,"d":"2.63E-34"},{"v":7.83457643967451e-33,"d":"7.83E-33"},"down","yes","Ptprcap","protein_coding","chr1:201449113-201451288:+","gi|66730347|ref|NP_001019460.1|",705,{"v":8E-90,"d":"8.00E-90"},"protein tyrosine phosphatase receptor type C-associated protein precursor [Rattus norvegicus]","gi|298910651|emb|FQ225639.1|",851,0,"Rattus norvegicus TL0AEA4YF15 mRNA sequence","Q64697",200,{"v":9e-62,"d":"9.00E-62"},"Protein tyrosine phosphatase receptor type C-associated protein",".",".",".",".","pfam15258","FAM222A","Protein family of FAM222A. This protein family, FAM222A are a domain of unknown function. This family of proteins is found in eukaryotes and are typically between 411 and 562 amino acids in length. In humans, the gene encoding this protein domain lies in the position, chromosome 12 open reading frame 34.",".","GO:0005886|plasma membrane;GO:0016021|integral component of membrane;",".",".","."]
["ENSRNOG00000006767",278,18.9696712763255,23.3896046837094,839,56.4958379403063,69.6593681803976,0.335771128775344,-1.57444990917263,{"v":1.64659570079733e-64,"d":"1.65E-64"},{"v":1.00395492593131e-62,"d":"1.00E-62"},"down","yes","Cst7","protein_coding","chr3:139396850-139405557:+","gi|157820635|ref|NP_001099993.1|",711,{"v":6e-90,"d":"6.00E-90"},"cystatin-F precursor [Rattus norvegicus]","gi|157820634|ref|NM_001106523.1|",1140,0,"Rattus norvegicus cystatin F (Cst7), mRNA","O89098",244,{"v":2E-78,"d":"2.00E-78"},"Cystatin-F",".",".",".",".","pfam00031","Cystatin","Cystatin domain. Very diverse family. Attempts to define separate sub-families failed. Typically, either the N-terminal or C-terminal end is very divergent. But splitting into two domains would make very short families. pfam00666 are related to this family but have not been included.","GO:0006955|immune response;GO:0010466|negative regulation of peptidase activity;GO:0031643|positive regulation of myelination;GO:0097340|inhibition of cysteine-type endopeptidase activity;GO:1903979|negative regulation of microglial cell activation;","GO:0005615|extracellular space;GO:0005737|cytoplasm;GO:0005764|lysosome;GO:0005768|endosome;GO:0005770|late endosome;GO:0005771|multivesicular body;GO:0005783|endoplasmic reticulum;GO:0005794|Golgi apparatus;GO:0031410|cytoplasmic vesicle;","GO:0004869|cysteine-type endopeptidase inhibitor activity;GO:0030414|peptidase inhibitor activity;GO:0042803|protein homodimerization activity;","K13903","CST7; cystatin-F"]
["ENSRNOG00000070875",378,4.93454329687403,31.8031315483531,1145,14.7502756091574,95.0655263010194,0.334539057277717,-1.57975344021955,{"v":8.93645230329631e-88,"d":"8.94E-88"},{"v":7.50390246696175e-86,"d":"7.50E-86"},"down","yes","Nat8f4","protein_coding","chr4:118325874-118332658:-","gi|564303978|ref|XP_006225040.1|",1128,{"v":3e-138,"d":"3.00E-138"},"PREDICTED: probable N-acetyltransferase CML2 [Rattus norvegicus]","gi|672050329|ref|XM_008763098.1|",5328,0,"PREDICTED: Rattus norvegicus probable N-acetyltransferase CML2-like (LOC102556148), transcript variant X1, mRNA","P85118",399,{"v":2E-125,"d":"2.00E-125"},"N-acetyltransferase family 8 member 2",".",".",".",".","pfam00583","Acetyltransf_1","Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.",".",".",".",".","."]
["ENSRNOG00000067705",251,2.48504970937345,21.1179524302556,763,7.45461779012763,63.3493419805046,0.333357092118724,-1.58485967434008,{"v":2.21978772547802e-59,"d":"2.22E-59"},{"v":1.24263111907781E-57,"d":"1.24E-57"},"down","yes","Klf2","protein_coding","chr16:17514552-17523944:-","gi|56090542|ref|NP_001007685.1|",1095,{"v":1e-130,"d":"1.00E-130"},"Krueppel-like factor 2 [Rattus norvegicus]","gi|170784839|ref|NM_008452.2|",1104,0,"Mus musculus Kruppel-like factor 2 (lung) (Klf2), mRNA","Q9ET58",426,{"v":3E-132,"d":"3.00E-132"},"Krueppel-like factor 2",".",".",".",".","pfam13465","zf-H2C2_2","Zinc-finger double domain.",".",".",".",".","."]
["ENSRNOG00000020833",130,4.98522558069133,10.9375849240367,403,15.2505670882123,33.4597441915378,0.326887882388621,-1.61313219695583,{"v":5.62357477679016e-33,"d":"5.62E-33"},{"v":1.6165722931216E-31,"d":"1.62E-31"},"down","yes","Cspg5","protein_coding","chr8:110220653-110234758:+","gi|41281651|ref|NP_598413.1|",2658,0,"chondroitin sulfate proteoglycan 5 isoform 2 precursor [Rattus norvegicus]","gi|41281650|ref|NM_133652.1|",1704,0,"Rattus norvegicus chondroitin sulfate proteoglycan 5 (Cspg5), transcript variant 2, mRNA","Q9ERQ6",1030,0,"Chondroitin sulfate proteoglycan 5",".",".",".",".","pfam06566","Chon_Sulph_att","Chondroitin sulphate attachment domain. This family represents the chondroitin sulphate attachment domain of vertebrate neural transmembrane proteoglycans that contain EGF modules. Evidence has been accumulated to support the idea that neural proteoglycans are involved in various cellular events including mitogenesis, differentiation, axonal outgrowth and synaptogenesis. This domain contains several potential sites of chondroitin sulphate attachment, as well as potential sites of N-linked glycosylation.","GO:0007010|cytoskeleton organization;GO:0007399|nervous system development;GO:0031103|axon regeneration;GO:0040008|regulation of growth;GO:0048858|cell projection morphogenesis;GO:0050804|modulation of chemical synaptic transmission;GO:0099550|trans-synaptic signaling, modulating synaptic transmission;GO:0106091|glial cell projection elongation;GO:1900026|positive regulation of substrate adhesion-dependent cell spreading;GO:2000300|regulation of synaptic vesicle exocytosis;","GO:0000139|Golgi membrane;GO:0005789|endoplasmic reticulum membrane;GO:0005794|Golgi apparatus;GO:0009986|cell surface;GO:0030660|Golgi-associated vesicle membrane;GO:0045202|synapse;GO:0098978|glutamatergic synapse;GO:0098982|GABA-ergic synapse;GO:0099055|integral component of postsynaptic membrane;","GO:0005515|protein binding;","K08116","CSPG5; chondroitin sulfate proteoglycan 5"]
["ENSRNOG00000019741",1827,82.509466353752,153.71513581704,5748,256.165992859457,477.23724469717,0.322093754259644,-1.63444740928616,0,0,"down","yes","Isyna1","protein_coding","chr16:18839145-18841979:-","gi|189163481|ref|NP_001013902.2|",2882,0,"inositol-3-phosphate synthase 1 [Rattus norvegicus]","gi|189163480|ref|NM_001013880.2|",1863,0,"Rattus norvegicus inositol-3-phosphate synthase 1 (Isyna1), mRNA","Q6AYK3",1114,0,"Inositol-3-phosphate synthase 1","YJL153c",525,{"v":4e-179,"d":"4.00E-179"},"COG1260","pfam07994","NAD_binding_5","Myo-inositol-1-phosphate synthase. This is a family of myo-inositol-1-phosphate synthases. Inositol-1-phosphate catalyses the conversion of glucose-6- phosphate to inositol-1-phosphate, which is then dephosphorylated to inositol. Inositol phosphates play an important role in signal transduction.","GO:0006021|inositol biosynthetic process;GO:0008654|phospholipid biosynthetic process;","GO:0005737|cytoplasm;","GO:0004512|inositol-3-phosphate synthase activity;","K01858","INO1, ISYNA1; myo-inositol-1-phosphate synthase [EC:5.5.1.4]"]
["ENSRNOG00000029450",157,2.20964154859327,13.2092371774905,500,6.94435099739945,41.5133302624539,0.318192664717084,-1.65202751722678,{"v":7.54264846000526e-42,"d":"7.54E-42"},{"v":2.92316818966368E-40,"d":"2.92E-40"},"down","yes","Adgrb1","protein_coding","chr7:106404958-106476902:+","gi|294345428|ref|NP_001164068.2|",7384,0,"brain-specific angiogenesis inhibitor 1 precursor [Rattus norvegicus]","gi|294345427|ref|NM_001170597.2|",5511,0,"Rattus norvegicus brain-specific angiogenesis inhibitor 1 (Bai1), mRNA","C0HL12",2848,0,"Adhesion G protein-coupled receptor B1",".",".",".",".","pfam00002","7tm_2","7 transmembrane receptor (Secretin family). This family is known as Family B, the secretin-receptor family or family 2 of the G-protein-coupled receptors (GCPRs).They have been described in many animal species, but not in plants, fungi or prokaryotes. Three distinct sub-families are recognized. Subfamily B1 contains classical hormone receptors, such as receptors for secretin and glucagon, that are all involved in cAMP-mediated signalling pathways. Subfamily B2 contains receptors with long extracellular N-termini, such as the leukocyte cell-surface antigen CD97; calcium-independent receptors for latrotoxin, and brain-specific angiogenesis inhibitors amongst others. Subfamily B3 includes Methuselah and other Drosophila proteins. Other than the typical seven-transmembrane region, characteristic structural features include an amino-terminal extracellular domain involved in ligand binding, and an intracellular loop (IC3) required for specific G-protein coupling.","GO:0006910|phagocytosis, recognition;GO:0006911|phagocytosis, engulfment;GO:0007166|cell surface receptor signaling pathway;GO:0007189|adenylate cyclase-activating G protein-coupled receptor signaling pathway;GO:0007399|nervous system development;GO:0007517|muscle organ development;GO:0010596|negative regulation of endothelial cell migration;GO:0016525|negative regulation of angiogenesis;GO:0031397|negative regulation of protein ubiquitination;GO:0042177|negative regulation of protein catabolic process;GO:0043277|apoptotic cell clearance;GO:0043652|engulfment of apoptotic cell;GO:0045087|innate immune response;GO:0048167|regulation of synaptic plasticity;GO:0050829|defense response to Gram-negative bacterium;GO:0051963|regulation of synapse assembly;GO:0051965|positive regulation of synapse assembly;GO:0098974|postsynaptic actin cytoskeleton organization;GO:1901741|positive regulation of myoblast fusion;GO:1903428|positive regulation of reactive oxygen species biosynthetic process;","GO:0001891|phagocytic cup;GO:0005615|extracellular space;GO:0005886|plasma membrane;GO:0005887|integral component of plasma membrane;GO:0005925|focal adhesion;GO:0014069|postsynaptic density;GO:0030425|dendrite;GO:0043197|dendritic spine;GO:0048471|perinuclear region of cytoplasm;GO:0098978|glutamatergic synapse;GO:0099055|integral component of postsynaptic membrane;","GO:0001530|lipopolysaccharide binding;GO:0001786|phosphatidylserine binding;GO:0004888|transmembrane signaling receptor activity;GO:0004930|G protein-coupled receptor activity;GO:0005515|protein binding;GO:0030165|PDZ domain binding;","K04596","ADGRB1, BAI1; adhesion G protein-coupled receptor B1"]
["ENSRNOG00000047314",343,9.978698874733,28.8583971457278,1096,31.4651521214726,90.9972199352989,0.317134931883048,-1.65683129824403,{"v":6.21090885794297e-90,"d":"6.21E-90"},{"v":5.50501226554991e-88,"d":"5.51E-88"},"down","yes","Tk1","protein_coding","chr10:103031521-103046920:-","gi|158186787|ref|NP_434687.1|",1171,{"v":7e-153,"d":"7.00E-153"},"thymidine kinase, cytosolic [Rattus norvegicus]","gi|158186786|ref|NM_052800.1|",2207,0,"Rattus norvegicus thymidine kinase 1, soluble (Tk1), mRNA","P04184",406,{"v":4e-135,"d":"4.00E-135"},"Thymidine kinase, cytosolic","MYPU_1450",94.4,{"v":9e-21,"d":"9.00E-21"},"COG1435","pfam00265","TK","Thymidine kinase.","GO:0001889|liver development;GO:0009157|deoxyribonucleoside monophosphate biosynthetic process;GO:0009636|response to toxic substance;GO:0014856|skeletal muscle cell proliferation;GO:0016310|phosphorylation;GO:0031667|response to nutrient levels;GO:0046104|thymidine metabolic process;GO:0046688|response to copper ion;GO:0048565|digestive tract development;GO:0051289|protein homotetramerization;GO:0051414|response to cortisol;GO:0060138|fetal process involved in parturition;GO:0071897|DNA biosynthetic process;","GO:0005737|cytoplasm;","GO:0003674|molecular_function;GO:0004797|thymidine kinase activity;GO:0005524|ATP binding;GO:0008270|zinc ion binding;GO:0042802|identical protein binding;","K00857","tdk, TK; thymidine kinase [EC:2.7.1.21]"]
["ENSRNOG00000038129",110,22.3009145809832,9.25487955110805,355,71.0228059911862,29.4744644863422,0.313996529280337,-1.6711794823237,{"v":1.11432571570261E-30,"d":"1.11E-30"},{"v":2.93047256280759e-29,"d":"2.93E-29"},"down","yes","Defb52","protein_coding","chr16:70588116-70590626:+","gi|564389783|ref|XP_006253430.1|",551,{"v":5e-70,"d":"5.00E-70"},"PREDICTED: beta-defensin 52 isoform X1 [Rattus norvegicus]","gi|672080546|ref|XM_006253368.2|",415,0,"PREDICTED: Rattus norvegicus defensin beta 52 (Defb52), transcript variant X1, mRNA",".",".",".",".",".",".",".",".","pfam01537","Herpes_glycop_D","Herpesvirus glycoprotein D/GG/GX domain. This domain is found in several Herpes viruses glycoproteins. This is a family includes glycoprotein-D (gD or gIV) which is common to herpes simplex virus types 1 and 2, as well as equine herpes, bovine herpes and Marek's disease virus. Glycoprotein-D has been found on the viral envelope and the plasma membrane of infected cells. and gD immunisation can produce an immune response to bovine herpes virus (BHV-1). This response is stronger than that of the other major glycoproteins gB (gI) and gC (gIII) in BHV-1. Glycoprotein G (gG)is one of the seven external glycoproteins of HSV1 and HSV2. This family also contains the glycoprotein GX, (gX), initially identified in Pseudorabies virus.",".",".",".",".","."]
["ENSRNOG00000009339",615,6.80921045105391,51.7431902175586,2010,21.9612564357237,166.883587655064,0.310055595907416,-1.68940116729601,{"v":8.15415750243191e-168,"d":"8.15E-168"},{"v":1.39385616099725e-165,"d":"1.39E-165"},"down","yes","Cenpe","protein_coding","chr2:223636998-223695669:+","gi|672044374|ref|XP_006233412.2|",11903,0,"PREDICTED: centromere-associated protein E isoform X2 [Rattus norvegicus]","gi|672044373|ref|XM_006233350.2|",7599,0,"PREDICTED: Rattus norvegicus centromere protein E (Cenpe), transcript variant X2, mRNA","Q6RT24",3648,0,"Centromere-associated protein E","SPAC1834.07",222,{"v":7e-60,"d":"7.00E-60"},"COG5059","pfam00225","Kinesin","Kinesin motor domain.","GO:0000278|mitotic cell cycle;GO:0007018|microtubule-based movement;GO:0007052|mitotic spindle organization;GO:0007057|spindle assembly involved in female meiosis I;GO:0007059|chromosome segregation;GO:0007079|mitotic chromosome movement towards spindle pole;GO:0007080|mitotic metaphase plate congression;GO:0007088|regulation of mitotic nuclear division;GO:0007094|mitotic spindle assembly checkpoint;GO:0008608|attachment of spindle microtubules to kinetochore;GO:0030071|regulation of mitotic metaphase/anaphase transition;GO:0031647|regulation of protein stability;GO:0045184|establishment of protein localization;GO:0045842|positive regulation of mitotic metaphase/anaphase transition;GO:0045860|positive regulation of protein kinase activity;GO:0050793|regulation of developmental process;GO:0051310|metaphase plate congression;GO:0051315|attachment of mitotic spindle microtubules to kinetochore;GO:0051382|kinetochore assembly;GO:0051984|positive regulation of chromosome segregation;GO:0051987|positive regulation of attachment of spindle microtubules to kinetochore;GO:0099606|microtubule plus-end directed mitotic chromosome migration;GO:0099607|lateral attachment of mitotic spindle microtubules to kinetochore;","GO:0000775|chromosome, centromeric region;GO:0000776|kinetochore;GO:0000779|condensed chromosome, centromeric region;GO:0000940|condensed chromosome outer kinetochore;GO:0005634|nucleus;GO:0005654|nucleoplasm;GO:0005694|chromosome;GO:0005828|kinetochore microtubule;GO:0005829|cytosol;GO:0005874|microtubule;GO:0015630|microtubule cytoskeleton;GO:0030496|midbody;GO:0051233|spindle midzone;GO:1990023|mitotic spindle midzone;","GO:0003777|microtubule motor activity;GO:0005524|ATP binding;GO:0008017|microtubule binding;GO:0008574|ATP-dependent microtubule motor activity, plus-end-directed;GO:0019901|protein kinase binding;GO:0043515|kinetochore binding;","K11498","CENPE; centromeric protein E"]
["ENSRNOG00000004084",263,2.73348680098985,22.1275756540128,867,8.89241688389068,71.984114675095,0.30739526010547,-1.70183317538585,{"v":3.10482425990835E-74,"d":"3.10E-74"},{"v":2.26878121523412e-72,"d":"2.27E-72"},"down","yes","Lratd1","protein_coding","chr6:36913469-36922319:-","gi|148666046|gb|EDK98462.1|",1515,0,"expressed sequence AW125753, isoform CRA_b, partial [Mus musculus]","gi|672055795|ref|XM_006239901.2|",4071,0,"PREDICTED: Rattus norvegicus family with sequence similarity 84, member A (Fam84a), transcript variant X1, mRNA",".",".",".",".",".",".",".",".","pfam04970","LRAT","Lecithin retinol acyltransferase. The full-length members of this family are representatives of a novel class II tumor-suppressor family, designated as H-REV107-like. This domain is the catalytic N-terminal proline-rich region of the protein. The downstream region is a putative C-terminal transmembrane domain which is found to be crucial for cellular localisation, but not necessary for the enzyme activity. H-REV107-like proteins are homologous to lecithin retinol acyltransferase (LRAT), an enzyme that catalyses the transfer of the sn-1 acyl group of phosphatidylcholine to all-trans-retinol and forming a retinyl ester.","GO:0000902|cell morphogenesis;GO:0048870|cell motility;",".",".","K22805","FAM84A, NSE1; protein FAM84A"]
["ENSRNOG00000018059",256,9.48003027002105,21.5386287734878,853,31.1715411213672,70.8217414277463,0.304124529265662,-1.71726591277461,{"v":5.62606362514679e-74,"d":"5.63E-74"},{"v":4.07997590492145e-72,"d":"4.08E-72"},"down","yes","Ihh","protein_coding","chr9:76504315-76510532:-","gi|1890097|gb|AAB49692.1|",2045,0,"Indian hedgehog protein [Mus musculus]","gi|213688397|ref|NM_053384.1|",2272,0,"Rattus norvegicus Indian hedgehog (Ihh), mRNA","P97812",726,0,"Indian hedgehog protein",".",".",".",".","pfam01085","HH_signal","Hedgehog amino-terminal signalling domain. For the carboxyl Hint module, see pfam01079. Hedgehog is a family of secreted signal molecules required for embryonic cell differentiation.","GO:0001501|skeletal system development;GO:0001503|ossification;GO:0001569|branching involved in blood vessel morphogenesis;GO:0001649|osteoblast differentiation;GO:0001701|in utero embryonic development;GO:0001708|cell fate specification;GO:0001763|morphogenesis of a branching structure;GO:0001944|vasculature development;GO:0001947|heart looping;GO:0002053|positive regulation of mesenchymal cell proliferation;GO:0003382|epithelial cell morphogenesis;GO:0003406|retinal pigment epithelium development;GO:0003413|chondrocyte differentiation involved in endochondral bone morphogenesis;GO:0006029|proteoglycan metabolic process;GO:0007224|smoothened signaling pathway;GO:0007267|cell-cell signaling;GO:0007389|pattern specification process;GO:0008284|positive regulation of cell proliferation;GO:0009612|response to mechanical stimulus;GO:0009880|embryonic pattern specification;GO:0010468|regulation of gene expression;GO:0016539|intein-mediated protein splicing;GO:0016540|protein autoprocessing;GO:0030154|cell differentiation;GO:0030704|vitelline membrane formation;GO:0031016|pancreas development;GO:0032355|response to estradiol;GO:0032967|positive regulation of collagen biosynthetic process;GO:0033085|negative regulation of T cell differentiation in thymus;GO:0033088|negative regulation of immature T cell proliferation in thymus;GO:0033089|positive regulation of T cell differentiation in thymus;GO:0035264|multicellular organism growth;GO:0035988|chondrocyte proliferation;GO:0040008|regulation of growth;GO:0042733|embryonic digit morphogenesis;GO:0043010|camera-type eye development;GO:0043066|negative regulation of apoptotic process;GO:0045453|bone resorption;GO:0045596|negative regulation of cell differentiation;GO:0045880|positive regulation of smoothened signaling pathway;GO:0045944|positive regulation of transcription by RNA polymerase II;GO:0046638|positive regulation of alpha-beta T cell differentiation;GO:0046639|negative regulation of alpha-beta T cell differentiation;GO:0048074|negative regulation of eye pigmentation;GO:0048469|cell maturation;GO:0048557|embryonic digestive tract morphogenesis;GO:0048596|embryonic camera-type eye morphogenesis;GO:0048666|neuron development;GO:0048745|smooth muscle tissue development;GO:0050679|positive regulation of epithelial cell proliferation;GO:0051216|cartilage development;GO:0060135|maternal process involved in female pregnancy;GO:0060220|camera-type eye photoreceptor cell fate commitment;GO:0060323|head morphogenesis;GO:0061053|somite development;GO:0072498|embryonic skeletal joint development;GO:0090136|epithelial cell-cell adhesion;GO:0097421|liver regeneration;","GO:0005575|cellular_component;GO:0005615|extracellular space;GO:0005886|plasma membrane;GO:0031012|extracellular matrix;","GO:0003674|molecular_function;GO:0005113|patched binding;GO:0005509|calcium ion binding;GO:0008233|peptidase activity;","K11989","IHH; indian hedgehog"]
["ENSRNOG00000002418",267,4.0948080074004,22.4641167285986,893,13.5149121124211,74.1428078487426,0.302984434773865,-1.72268441488999,{"v":1.08252584946945E-77,"d":"1.08E-77"},{"v":8.15946050951566e-76,"d":"8.16E-76"},"down","yes","Tgfb2","protein_coding","chr13:98160087-98261405:-","gi|149040974|gb|EDL94931.1|",2044,0,"transforming growth factor, beta 2, isoform CRA_a [Rattus norvegicus]","gi|672075217|ref|XM_006250448.2|",3531,0,"PREDICTED: Rattus norvegicus transforming growth factor, beta 2 (Tgfb2), transcript variant X1, mRNA","Q07257",789,0,"Transforming growth factor beta-2",".",".",".",".","pfam00019","TGF_beta","Transforming growth factor beta like domain.","GO:0000902|cell morphogenesis;GO:0001501|skeletal system development;GO:0001502|cartilage condensation;GO:0001558|regulation of cell growth;GO:0001568|blood vessel development;GO:0001654|eye development;GO:0001666|response to hypoxia;GO:0001822|kidney development;GO:0001837|epithelial to mesenchymal transition;GO:0001843|neural tube closure;GO:0001942|hair follicle development;GO:0001974|blood vessel remodeling;GO:0003007|heart morphogenesis;GO:0003148|outflow tract septum morphogenesis;GO:0003149|membranous septum morphogenesis;GO:0003179|heart valve morphogenesis;GO:0003181|atrioventricular valve morphogenesis;GO:0003184|pulmonary valve morphogenesis;GO:0003203|endocardial cushion morphogenesis;GO:0003215|cardiac right ventricle morphogenesis;GO:0003222|ventricular trabecula myocardium morphogenesis;GO:0003274|endocardial cushion fusion;GO:0003289|atrial septum primum morphogenesis;GO:0003407|neural retina development;GO:0006468|protein phosphorylation;GO:0007165|signal transduction;GO:0007179|transforming growth factor beta receptor signaling pathway;GO:0007411|axon guidance;GO:0007435|salivary gland morphogenesis;GO:0007507|heart development;GO:0007519|skeletal muscle tissue development;GO:0007565|female pregnancy;GO:0007568|aging;GO:0008219|cell death;GO:0008284|positive regulation of cell proliferation;GO:0008285|negative regulation of cell proliferation;GO:0008347|glial cell migration;GO:0008584|male gonad development;GO:0009314|response to radiation;GO:0009409|response to cold;GO:0009410|response to xenobiotic stimulus;GO:0009611|response to wounding;GO:0010002|cardioblast differentiation;GO:0010243|response to organonitrogen compound;GO:0010628|positive regulation of gene expression;GO:0010629|negative regulation of gene expression;GO:0010634|positive regulation of epithelial cell migration;GO:0010693|negative regulation of alkaline phosphatase activity;GO:0010718|positive regulation of epithelial to mesenchymal transition;GO:0010862|positive regulation of pathway-restricted SMAD protein phosphorylation;GO:0010936|negative regulation of macrophage cytokine production;GO:0014068|positive regulation of phosphatidylinositol 3-kinase signaling;GO:0016477|cell migration;GO:0016525|negative regulation of angiogenesis;GO:0030097|hemopoiesis;GO:0030198|extracellular matrix organization;GO:0030199|collagen fibril organization;GO:0030307|positive regulation of cell growth;GO:0030308|negative regulation of cell growth;GO:0030324|lung development;GO:0030326|embryonic limb morphogenesis;GO:0030335|positive regulation of cell migration;GO:0030509|BMP signaling pathway;GO:0030593|neutrophil chemotaxis;GO:0030878|thyroid gland development;GO:0030902|hindbrain development;GO:0031016|pancreas development;GO:0031069|hair follicle morphogenesis;GO:0032147|activation of protein kinase activity;GO:0032355|response to estradiol;GO:0032526|response to retinoic acid;GO:0032570|response to progesterone;GO:0032874|positive regulation of stress-activated MAPK cascade;GO:0032909|regulation of transforming growth factor beta2 production;GO:0032956|regulation of actin cytoskeleton organization;GO:0033280|response to vitamin D;GO:0033630|positive regulation of cell adhesion mediated by integrin;GO:0034097|response to cytokine;GO:0034616|response to laminar fluid shear stress;GO:0035910|ascending aorta morphogenesis;GO:0042060|wound healing;GO:0042127|regulation of cell proliferation;GO:0042416|dopamine biosynthetic process;GO:0042981|regulation of apoptotic process;GO:0043065|positive regulation of apoptotic process;GO:0043066|negative regulation of apoptotic process;GO:0043525|positive regulation of neuron apoptotic process;GO:0043627|response to estrogen;GO:0045216|cell-cell junction organization;GO:0045726|positive regulation of integrin biosynthetic process;GO:0045747|positive regulation of Notch signaling pathway;GO:0045778|positive regulation of ossification;GO:0045787|positive regulation of cell cycle;GO:0045823|positive regulation of heart contraction;GO:0046580|negative regulation of Ras protein signal transduction;GO:0048103|somatic stem cell division;GO:0048565|digestive tract development;GO:0048566|embryonic digestive tract development;GO:0048663|neuron fate commitment;GO:0048666|neuron development;GO:0048702|embryonic neurocranium morphogenesis;GO:0048839|inner ear development;GO:0050680|negative regulation of epithelial cell proliferation;GO:0050714|positive regulation of protein secretion;GO:0050777|negative regulation of immune response;GO:0050778|positive regulation of immune response;GO:0051280|negative regulation of release of sequestered calcium ion into cytosol;GO:0051726|regulation of cell cycle;GO:0051781|positive regulation of cell division;GO:0051794|regulation of timing of catagen;GO:0051795|positive regulation of timing of catagen;GO:0051891|positive regulation of cardioblast differentiation;GO:0060038|cardiac muscle cell proliferation;GO:0060065|uterus development;GO:0060317|cardiac epithelial to mesenchymal transition;GO:0060325|face morphogenesis;GO:0060364|frontal suture morphogenesis;GO:0060389|pathway-restricted SMAD protein phosphorylation;GO:0060395|SMAD protein signal transduction;GO:0060412|ventricular septum morphogenesis;GO:0060413|atrial septum morphogenesis;GO:0061037|negative regulation of cartilage development;GO:0061626|pharyngeal arch artery morphogenesis;GO:0062009|secondary palate development;GO:0070237|positive regulation of activation-induced cell death of T cells;GO:0090091|positive regulation of extracellular matrix disassembly;GO:0097191|extrinsic apoptotic signaling pathway;GO:1900182|positive regulation of protein localization to nucleus;GO:1902256|regulation of apoptotic process involved in outflow tract morphogenesis;GO:1902895|positive regulation of pri-miRNA transcription by RNA polymerase II;GO:1903053|regulation of extracellular matrix organization;GO:1903701|substantia propria of cornea development;GO:1904238|pericyte cell differentiation;GO:1904426|positive regulation of GTP binding;GO:1904888|cranial skeletal system development;GO:1905006|negative regulation of epithelial to mesenchymal transition involved in endocardial cushion formation;GO:1905007|positive regulation of epithelial to mesenchymal transition involved in endocardial cushion formation;GO:2001241|positive regulation of extrinsic apoptotic signaling pathway in absence of ligand;","GO:0005576|extracellular region;GO:0005604|basement membrane;GO:0005615|extracellular space;GO:0005737|cytoplasm;GO:0005768|endosome;GO:0005802|trans-Golgi network;GO:0009986|cell surface;GO:0030141|secretory granule;GO:0030424|axon;GO:0031012|extracellular matrix;GO:0043025|neuronal cell body;GO:0062023|collagen-containing extracellular matrix;","GO:0001540|amyloid-beta binding;GO:0005102|signaling receptor binding;GO:0005114|type II transforming growth factor beta receptor binding;GO:0005125|cytokine activity;GO:0005160|transforming growth factor beta receptor binding;GO:0008083|growth factor activity;GO:0034714|type III transforming growth factor beta receptor binding;GO:0042802|identical protein binding;GO:0042803|protein homodimerization activity;GO:0044877|protein-containing complex binding;GO:0047485|protein N-terminus binding;","K13376","TGFB2; transforming growth factor beta-2"]
["ENSRNOG00000008245",164,4.01693859039756,13.7981840580156,550,13.2939339996213,45.6646632886993,0.302163271647954,-1.72659978525026,{"v":1.06314307832933E-48,"d":"1.06E-48"},{"v":4.91641189517927e-47,"d":"4.92E-47"},"down","yes","AABR07054614.1","protein_coding","chr3:155916412-155965451:-","gi|13928752|ref|NP_113745.1|",2482,0,"prostacyclin synthase precursor [Rattus norvegicus]","gi|42476132|ref|NM_031557.2|",1563,0,"Rattus norvegicus prostaglandin I2 (prostacyclin) synthase (Ptgis), mRNA","Q62969",960,0,"Prostacyclin synthase","YHR007c",78.6,{"v":4E-14,"d":"4.00E-14"},"COG2124","pfam00067","p450","Cytochrome P450. Cytochrome P450s are haem-thiolate proteins involved in the oxidative degradation of various compounds. They are particularly well known for their role in the degradation of environmental toxins and mutagens. They can be divided into 4 classes, according to the method by which electrons from NAD(P)H are delivered to the catalytic site. Sequence conservation is relatively low within the family - there are only 3 absolutely conserved residues - but their general topography and structural fold are highly conserved. The conserved core is composed of a coil termed the 'meander', a four-helix bundle, helices J and K, and two sets of beta-sheets. These constitute the haem-binding loop (with an absolutely conserved cysteine that serves as the 5th ligand for the haem iron), the proton-transfer groove and the absolutely conserved EXXR motif in helix K. While prokaryotic P450s are soluble proteins, most eukaryotic P450s are associated with microsomal membranes. their general enzymatic function is to catalyse regiospecific and stereospecific oxidation of non-activated hydrocarbons at physiological temperatures.",".",".",".",".","."]
["ENSRNOG00000019955",200,4.54294107162186,16.8270537292873,679,15.2200600692258,56.3751024964124,0.298483780678859,-1.74427555592633,{"v":1.56904477463844e-60,"d":"1.57E-60"},{"v":9.10286879181993e-59,"d":"9.10E-59"},"down","yes","Ogdhl","protein_coding","chr16:7578367-7604386:+","gi|157819765|ref|NP_001099532.1|",5502,0,"2-oxoglutarate dehydrogenase-like, mitochondrial [Rattus norvegicus]","gi|157819764|ref|NM_001106062.1|",3526,0,"Rattus norvegicus oxoglutarate dehydrogenase-like (Ogdhl), mRNA","Q9ULD0",1916,0,"2-oxoglutarate dehydrogenase-like, mitochondrial","SPBC3H7.03c",835,0,"COG0567","pfam00676","E1_dh","Dehydrogenase E1 component. This family uses thiamine pyrophosphate as a cofactor. This family includes pyruvate dehydrogenase, 2-oxoglutarate dehydrogenase and 2-oxoisovalerate dehydrogenase.","GO:0006096|glycolytic process;GO:0006099|tricarboxylic acid cycle;GO:0006103|2-oxoglutarate metabolic process;","GO:0005739|mitochondrion;GO:0005759|mitochondrial matrix;GO:0045252|oxoglutarate dehydrogenase complex;","GO:0004591|oxoglutarate dehydrogenase (succinyl-transferring) activity;GO:0030976|thiamine pyrophosphate binding;GO:0046872|metal ion binding;","K00164","OGDH, sucA; 2-oxoglutarate dehydrogenase E1 component [EC:1.2.4.2]"]
["ENSRNOG00000017209",139,6.62219838157119,11.6948023418547,472,22.1905910349697,39.1885837677565,0.298423704494188,-1.74456595809465,{"v":1.24716331681564e-42,"d":"1.25E-42"},{"v":5.0586917379839e-41,"d":"5.06E-41"},"down","yes","Tubb3","protein_coding","chr19:51457184-51466243:+","gi|532003341|ref|XP_005345916.1|",2241,0,"PREDICTED: tubulin beta-3 chain [Microtus ochrogaster]","gi|145966773|ref|NM_139254.2|",1763,0,"Rattus norvegicus tubulin, beta 3 class III (Tubb3), mRNA","Q60HC2",857,0,"Tubulin beta-3 chain","ECU03g0820i",717,0,"COG5023","pfam03953","Tubulin_C","Tubulin C-terminal domain. This family includes the tubulin alpha, beta and gamma chains. Members of this family are involved in polymer formation. Tubulins are GTPases. FtsZ can polymerize into tubes, sheets, and rings in vitro and is ubiquitous in eubacteria and archaea. Tubulin is the major component of microtubules. (The FtsZ GTPases have been split into their won family).","GO:0000226|microtubule cytoskeleton organization;GO:0000278|mitotic cell cycle;GO:0007411|axon guidance;GO:0030182|neuron differentiation;GO:0038007|netrin-activated signaling pathway;GO:1990791|dorsal root ganglion development;","GO:0005737|cytoplasm;GO:0005874|microtubule;GO:0015630|microtubule cytoskeleton;GO:0030027|lamellipodium;GO:0030175|filopodium;GO:0030424|axon;GO:0030425|dendrite;GO:0030426|growth cone;GO:0043025|neuronal cell body;GO:0071944|cell periphery;","GO:0003924|GTPase activity;GO:0005200|structural constituent of cytoskeleton;GO:0005525|GTP binding;GO:0042277|peptide binding;GO:1990890|netrin receptor binding;","K07375","TUBB; tubulin beta"]
["ENSRNOG00000028908",117,13.4662468284994,9.84382643163311,410,46.5676208142437,34.0409308152122,0.289176182786226,-1.78997936137836,{"v":1.50726558573643e-38,"d":"1.51E-38"},{"v":5.32411444926317e-37,"d":"5.32E-37"},"down","yes","Eppin","protein_coding","chr3:153312396-153319310:-","gi|157822521|ref|NP_001102927.1|",594,{"v":1e-74,"d":"1.00E-74"},"eppin precursor [Rattus norvegicus]","gi|157822520|ref|NM_001109457.1|",731,0,"Rattus norvegicus epididymal peptidase inhibitor (Eppin), mRNA","D4A2Z2",233,{"v":5e-76,"d":"5.00E-76"},"Eppin",".",".",".",".","pfam00014","Kunitz_BPTI","Kunitz/Bovine pancreatic trypsin inhibitor domain. Indicative of a protease inhibitor, usually a serine protease inhibitor. Structure is a disulfide rich alpha+beta fold. BPTI (bovine pancreatic trypsin inhibitor) is an extensively studied model structure. Certain family members are similar to the tick anticoagulant peptide (TAP). This is a highly selective inhibitor of factor Xa in the blood coagulation pathways. TAP molecules are highly dipolar, and are arranged to form a twisted two- stranded antiparallel beta-sheet followed by an alpha helix.","GO:0010466|negative regulation of peptidase activity;GO:0010951|negative regulation of endopeptidase activity;GO:0042742|defense response to bacterium;GO:0090281|negative regulation of calcium ion import;GO:1901318|negative regulation of flagellated sperm motility;","GO:0001669|acrosomal vesicle;GO:0005615|extracellular space;GO:0005737|cytoplasm;GO:0009986|cell surface;GO:0032991|protein-containing complex;","GO:0004867|serine-type endopeptidase inhibitor activity;","K23622","EPPIN; eppin"]
["ENSRNOG00000033215",938,15.1621291047757,78.9188819903577,3507,55.9413061404134,291.174498460851,0.271036379928609,-1.88344158419375,0,0,"down","yes","RT1-Db1","protein_coding","chr20:4548666-4558258:-","gi|57114286|ref|NP_001008884.1|",1137,{"v":2e-139,"d":"2.00E-139"},"rano class II histocompatibility antigen, D-1 beta chain precursor [Rattus norvegicus]","gi|89214481|gb|AC120734.5|",4227,0,"Rattus norvegicus BAC CH230-220D1 (Children's Hospital Oakland Research Institute Rat (BN/SsNHsd/MCW) BAC library) complete sequence","P18211",399,{"v":9e-126,"d":"9.00E-126"},"Rano class II histocompatibility antigen, D-1 beta chain",".",".",".",".","pfam00969","MHC_II_beta","Class II histocompatibility antigen, beta domain.","GO:0001916|positive regulation of T cell mediated cytotoxicity;GO:0001934|positive regulation of protein phosphorylation;GO:0002250|adaptive immune response;GO:0002381|immunoglobulin production involved in immunoglobulin mediated immune response;GO:0002437|inflammatory response to antigenic stimulus;GO:0002469|myeloid dendritic cell antigen processing and presentation;GO:0002491|antigen processing and presentation of endogenous peptide antigen via MHC class II;GO:0002503|peptide antigen assembly with MHC class II protein complex;GO:0002504|antigen processing and presentation of peptide or polysaccharide antigen via MHC class II;GO:0002842|positive regulation of T cell mediated immune response to tumor cell;GO:0002862|negative regulation of inflammatory response to antigenic stimulus;GO:0006955|immune response;GO:0006959|humoral immune response;GO:0007165|signal transduction;GO:0010033|response to organic substance;GO:0016045|detection of bacterium;GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II;GO:0030225|macrophage differentiation;GO:0032653|regulation of interleukin-10 production;GO:0032673|regulation of interleukin-4 production;GO:0032689|negative regulation of interferon-gamma production;GO:0032831|positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation;GO:0033674|positive regulation of kinase activity;GO:0034341|response to interferon-gamma;GO:0035774|positive regulation of insulin secretion involved in cellular response to glucose stimulus;GO:0042088|T-helper 1 type immune response;GO:0042130|negative regulation of T cell proliferation;GO:0043123|positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0043382|positive regulation of memory T cell differentiation;GO:0043410|positive regulation of MAPK cascade;GO:0045622|regulation of T-helper cell differentiation;GO:0045657|positive regulation of monocyte differentiation;GO:0045893|positive regulation of transcription, DNA-templated;GO:0046598|positive regulation of viral entry into host cell;GO:0050852|T cell receptor signaling pathway;GO:0050870|positive regulation of T cell activation;GO:0051262|protein tetramerization;GO:0070374|positive regulation of ERK1 and ERK2 cascade;GO:0071548|response to dexamethasone;GO:2000516|positive regulation of CD4-positive, alpha-beta T cell activation;","GO:0001772|immunological synapse;GO:0005575|cellular_component;GO:0005765|lysosomal membrane;GO:0009897|external side of plasma membrane;GO:0009986|cell surface;GO:0016021|integral component of membrane;GO:0031902|late endosome membrane;GO:0042613|MHC class II protein complex;","GO:0003674|molecular_function;GO:0023026|MHC class II protein complex binding;GO:0030247|polysaccharide binding;GO:0032395|MHC class II receptor activity;GO:0042605|peptide antigen binding;GO:0042608|T cell receptor binding;GO:0042609|CD4 receptor binding;","K06752","MHC2; MHC class II antigen"]
["ENSRNOG00000010906",251,17.6129711678529,21.1179524302556,1015,70.2852881007351,84.2720604327814,0.250592572696144,-1.99658443957808,{"v":3.91713528974547E-107,"d":"3.92E-107"},{"v":4.12053938256882e-105,"d":"4.12E-105"},"down","yes","Ccl5","protein_coding","chr10:68322829-68327377:-","gi|61889094|ref|NP_112378.2|",337,{"v":3e-35,"d":"3.00E-35"},"C-C motif chemokine 5 precursor [Rattus norvegicus]","gi|354800115|gb|JN964616.1|",465,0,"Mus musculus targeted KO-first, conditional ready, lacZ-tagged mutant allele Ccl5:tm1a(EUCOMM)Hmgu; transgenic","P50231",130,{"v":2E-35,"d":"2.00E-35"},"C-C motif chemokine 5",".",".",".",".","pfam00048","IL8","Small cytokines (intecrine/chemokine), interleukin-8 like. Includes a number of secreted growth factors and interferons involved in mitogenic, chemotactic, and inflammatory activity. Structure contains two highly conserved disulfide bonds.","GO:0000165|MAPK cascade;GO:0002544|chronic inflammatory response;GO:0002548|monocyte chemotaxis;GO:0006468|protein phosphorylation;GO:0006816|calcium ion transport;GO:0006874|cellular calcium ion homeostasis;GO:0006887|exocytosis;GO:0006954|inflammatory response;GO:0006955|immune response;GO:0007159|leukocyte cell-cell adhesion;GO:0007165|signal transduction;GO:0007186|G protein-coupled receptor signaling pathway;GO:0007267|cell-cell signaling;GO:0007568|aging;GO:0009410|response to xenobiotic stimulus;GO:0009615|response to virus;GO:0009617|response to bacterium;GO:0009636|response to toxic substance;GO:0009651|response to salt stress;GO:0010628|positive regulation of gene expression;GO:0010759|positive regulation of macrophage chemotaxis;GO:0010820|positive regulation of T cell chemotaxis;GO:0014068|positive regulation of phosphatidylinositol 3-kinase signaling;GO:0014070|response to organic cyclic compound;GO:0014823|response to activity;GO:0014911|positive regulation of smooth muscle cell migration;GO:0018894|dibenzo-p-dioxin metabolic process;GO:0030335|positive regulation of cell migration;GO:0030593|neutrophil chemotaxis;GO:0031269|pseudopodium assembly;GO:0031328|positive regulation of cellular biosynthetic process;GO:0031584|activation of phospholipase D activity;GO:0031622|positive regulation of fever generation;GO:0031663|lipopolysaccharide-mediated signaling pathway;GO:0031667|response to nutrient levels;GO:0032496|response to lipopolysaccharide;GO:0032868|response to insulin;GO:0033634|positive regulation of cell-cell adhesion mediated by integrin;GO:0034097|response to cytokine;GO:0034112|positive regulation of homotypic cell-cell adhesion;GO:0034341|response to interferon-gamma;GO:0034612|response to tumor necrosis factor;GO:0035688|T-helper 1 cell diapedesis;GO:0042102|positive regulation of T cell proliferation;GO:0042119|neutrophil activation;GO:0042327|positive regulation of phosphorylation;GO:0042531|positive regulation of tyrosine phosphorylation of STAT protein;GO:0043491|protein kinase B signaling;GO:0043547|positive regulation of GTPase activity;GO:0043627|response to estrogen;GO:0043922|negative regulation by host of viral transcription;GO:0044344|cellular response to fibroblast growth factor stimulus;GO:0045071|negative regulation of viral genome replication;GO:0045666|positive regulation of neuron differentiation;GO:0045672|positive regulation of osteoclast differentiation;GO:0045744|negative regulation of G protein-coupled receptor signaling pathway;GO:0045766|positive regulation of angiogenesis;GO:0045785|positive regulation of cell adhesion;GO:0048245|eosinophil chemotaxis;GO:0048247|lymphocyte chemotaxis;GO:0048661|positive regulation of smooth muscle cell proliferation;GO:0050679|positive regulation of epithelial cell proliferation;GO:0050796|regulation of insulin secretion;GO:0050863|regulation of T cell activation;GO:0050918|positive chemotaxis;GO:0051384|response to glucocorticoid;GO:0051928|positive regulation of calcium ion transport;GO:0060326|cell chemotaxis;GO:0060548|negative regulation of cell death;GO:0060754|positive regulation of mast cell chemotaxis;GO:0061098|positive regulation of protein tyrosine kinase activity;GO:0070098|chemokine-mediated signaling pathway;GO:0070100|negative regulation of chemokine-mediated signaling pathway;GO:0070233|negative regulation of T cell apoptotic process;GO:0070234|positive regulation of T cell apoptotic process;GO:0070374|positive regulation of ERK1 and ERK2 cascade;GO:0070723|response to cholesterol;GO:0071222|cellular response to lipopolysaccharide;GO:0071230|cellular response to amino acid stimulus;GO:0071307|cellular response to vitamin K;GO:0071315|cellular response to morphine;GO:0071345|cellular response to cytokine stimulus;GO:0071346|cellular response to interferon-gamma;GO:0071347|cellular response to interleukin-1;GO:0071356|cellular response to tumor necrosis factor;GO:0071361|cellular response to ethanol;GO:0071396|cellular response to lipid;GO:0071403|cellular response to high density lipoprotein particle stimulus;GO:0071407|cellular response to organic cyclic compound;GO:0071448|cellular response to alkyl hydroperoxide;GO:0071560|cellular response to transforming growth factor beta stimulus;GO:0090026|positive regulation of monocyte chemotaxis;GO:0097305|response to alcohol;GO:0098586|cellular response to virus;GO:1901214|regulation of neuron death;GO:1901215|negative regulation of neuron death;GO:2000110|negative regulation of macrophage apoptotic process;GO:2000406|positive regulation of T cell migration;GO:2000503|positive regulation of natural killer cell chemotaxis;","GO:0005615|extracellular space;GO:0005737|cytoplasm;","GO:0004435|phosphatidylinositol phospholipase C activity;GO:0004672|protein kinase activity;GO:0008009|chemokine activity;GO:0008201|heparin binding;GO:0016004|phospholipase activator activity;GO:0030298|receptor signaling protein tyrosine kinase activator activity;GO:0031726|CCR1 chemokine receptor binding;GO:0031730|CCR5 chemokine receptor binding;GO:0042056|chemoattractant activity;GO:0042379|chemokine receptor binding;GO:0042802|identical protein binding;GO:0042803|protein homodimerization activity;GO:0043621|protein self-association;GO:0046817|chemokine receptor antagonist activity;GO:0048020|CCR chemokine receptor binding;","K12499","CCL5; C-C motif chemokine 5"]
["ENSRNOG00000047321",629,96.5713211288481,52.9210839786087,2659,402.861113751331,220.767890335729,0.239713682538387,-2.0606158364347,{"v":7.09393242256078E-289,"d":"7.09E-289"},{"v":2.61180403963531E-286,"d":"2.61E-286"},"down","yes","Hba-a3","protein_coding","chr10:15311634-15312481:-","gi|62078447|ref|NP_001013875.1|",742,{"v":7e-98,"d":"7.00E-98"},"hemoglobin alpha, adult chain 1 [Rattus norvegicus]","gi|298900691|emb|FQ212394.1|",545,0,"Rattus norvegicus TL0AAA56YK17 mRNA sequence","P01944",235,{"v":9e-78,"d":"9.00E-78"},"Hemoglobin subunit alpha",".",".",".",".","pfam00042","Globin","Globin.","GO:0001701|in utero embryonic development;GO:0009617|response to bacterium;GO:0010942|positive regulation of cell death;GO:0015671|oxygen transport;GO:0032355|response to estradiol;GO:0042542|response to hydrogen peroxide;GO:0042744|hydrogen peroxide catabolic process;GO:0048821|erythrocyte development;GO:0098869|cellular oxidant detoxification;","GO:0005615|extracellular space;GO:0005833|hemoglobin complex;GO:0022627|cytosolic small ribosomal subunit;GO:0031838|haptoglobin-hemoglobin complex;","GO:0003674|molecular_function;GO:0004601|peroxidase activity;GO:0005344|oxygen carrier activity;GO:0005506|iron ion binding;GO:0005515|protein binding;GO:0019825|oxygen binding;GO:0020037|heme binding;GO:0031720|haptoglobin binding;GO:0043177|organic acid binding;","K13822","HBA; hemoglobin subunit alpha"]
["ENSRNOG00000016826",132,5.88857659667532,11.1058554613296,604,26.5896622253681,50.1481029570443,0.221461128267258,-2.17487460142294,{"v":9.41309043370117e-72,"d":"9.41E-72"},{"v":6.52950163368942e-70,"d":"6.53E-70"},"down","yes","Pla2g2d","protein_coding","chr5:151018870-151022525:+","gi|149024390|gb|EDL80887.1|",994,{"v":4e-128,"d":"4.00E-128"},"phospholipase A2, group IID [Rattus norvegicus]","gi|61740622|ref|NM_001013428.1|",1830,0,"Rattus norvegicus phospholipase A2, group IID (Pla2g2d), mRNA","Q9WVF6",261,{"v":6e-82,"d":"6.00E-82"},"Group IID secretory phospholipase A2",".",".",".",".","pfam00068","Phospholip_A2_1","Phospholipase A2. Phospholipase A2 releases fatty acids from the second carbon group of glycerol. Perhaps the best known members are secreted snake venoms, but also found in secreted pancreatic and membrane-associated forms. Structure is all-alpha, with two core disulfide-linked helices and a calcium-binding loop. This alignment represents the major family of PLA2s. A second minor family, defined by the honeybee venom PLA2 PDB:1POC and related sequences from Gila monsters (Heloderma), is not recognized. This minor family conserves the core helix pair but is substantially different elsewhere. The PROSITE pattern PA2_HIS, specific to the first core helix, recognizes both families.","GO:0002361|CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation;GO:0002864|regulation of acute inflammatory response to antigenic stimulus;GO:0006644|phospholipid metabolic process;GO:0016042|lipid catabolic process;GO:0042130|negative regulation of T cell proliferation;GO:0046337|phosphatidylethanolamine metabolic process;GO:0046470|phosphatidylcholine metabolic process;GO:0046471|phosphatidylglycerol metabolic process;GO:0050482|arachidonic acid secretion;GO:0050868|negative regulation of T cell activation;","GO:0005576|extracellular region;","GO:0004623|phospholipase A2 activity;GO:0005509|calcium ion binding;GO:0005543|phospholipid binding;GO:0008201|heparin binding;GO:0043395|heparan sulfate proteoglycan binding;GO:0047498|calcium-dependent phospholipase A2 activity;","K01047","PLA2G, SPLA2; secretory phospholipase A2 [EC:3.1.1.4]"]
["ENSRNOG00000030712",250,9.81054904925802,21.0338171616092,1149,44.4951646189921,95.3976329431191,0.220485734422264,-2.18124277944034,{"v":3.01911476913659e-135,"d":"3.02E-135"},{"v":4.25008484657655e-133,"d":"4.25E-133"},"down","yes","RT1-CE1","protein_coding","chr20:3555782-3559486:-","gi|57012398|ref|NP_001008832.1|",1642,0,"RT1 class I, locus CE1 precursor [Rattus norvegicus]","gi|110350025|gb|AC130591.5|",1181,0,"Rattus norvegicus BAC CH230-312A21 () complete sequence","P16391",528,0,"RT1 class I histocompatibility antigen, AA alpha chain",".",".",".",".","pfam00129","MHC_I","Class I Histocompatibility antigen, domains alpha 1 and 2.","GO:0001916|positive regulation of T cell mediated cytotoxicity;GO:0002476|antigen processing and presentation of endogenous peptide antigen via MHC class Ib;GO:0002485|antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent;GO:0002486|antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent;GO:0006955|immune response;GO:0010977|negative regulation of neuron projection development;","GO:0005615|extracellular space;GO:0005886|plasma membrane;GO:0009897|external side of plasma membrane;GO:0016021|integral component of membrane;GO:0045121|membrane raft;","GO:0005102|signaling receptor binding;GO:0005515|protein binding;GO:0042605|peptide antigen binding;","K06751","MHC1; MHC class I antigen"]
["ENSRNOG00000012280",122,5.33498065221688,10.2645027748652,590,25.4603584769727,48.9857297096956,0.209540673083689,-2.25469778814263,{"v":3.10848315689956e-73,"d":"3.11E-73"},{"v":2.22060140546353E-71,"d":"2.22E-71"},"down","yes","Ptx3","protein_coding","chr2:150487513-150493323:+","gi|157817545|ref|NP_001103006.1|",1933,0,"pentraxin-related protein PTX3 precursor [Rattus norvegicus]","gi|157817544|ref|NM_001109536.1|",1920,0,"Rattus norvegicus pentraxin 3 (Ptx3), mRNA","P48759",709,0,"Pentraxin-related protein PTX3",".",".",".",".","pfam00354","Pentaxin","Pentaxin family. Pentaxins are also known as pentraxins.","GO:0001550|ovarian cumulus expansion;GO:0001878|response to yeast;GO:0008228|opsonization;GO:0030198|extracellular matrix organization;GO:0044793|negative regulation by host of viral process;GO:0044869|negative regulation by host of viral exo-alpha-sialidase activity;GO:0044871|negative regulation by host of viral glycoprotein metabolic process;GO:0045087|innate immune response;GO:0045429|positive regulation of nitric oxide biosynthetic process;GO:0046597|negative regulation of viral entry into host cell;GO:0050766|positive regulation of phagocytosis;GO:1903016|negative regulation of exo-alpha-sialidase activity;GO:1903019|negative regulation of glycoprotein metabolic process;","GO:0005615|extracellular space;GO:0031012|extracellular matrix;","GO:0001849|complement component C1q binding;GO:0001872|(1->3)-beta-D-glucan binding;GO:0042802|identical protein binding;GO:0046790|virion binding;","K25724","PTX3; pentraxin-related protein PTX3"]
["ENSRNOG00000046699",126,21.202087698902,10.601043849451,660,109.595191892878,54.7975959464391,0.193458192213629,-2.36990627220222,{"v":1.30000912801972e-86,"d":"1.30E-86"},{"v":1.07279144778283E-84,"d":"1.07E-84"},"down","yes","Slpi","protein_coding","chr3:153082369-153084453:-","gi|149042957|gb|EDL96531.1|",659,{"v":8e-86,"d":"8.00E-86"},"rCG32428, isoform CRA_a [Rattus norvegicus]","gi|23451267|gb|AF421377.1|",444,0,"Rattus norvegicus secretory leukocyte protease inhibitor precursor, mRNA, complete cds","P97430",217,{"v":3e-71,"d":"3.00E-71"},"Antileukoproteinase",".",".",".",".","pfam00095","WAP","WAP-type (Whey Acidic Protein) 'four-disulfide core'.","GO:0006955|immune response;GO:0010951|negative regulation of endopeptidase activity;GO:0019731|antibacterial humoral response;GO:0032091|negative regulation of protein binding;GO:0032496|response to lipopolysaccharide;GO:0035821|modification of morphology or physiology of other organism;GO:0045071|negative regulation of viral genome replication;GO:0045087|innate immune response;GO:0050728|negative regulation of inflammatory response;","GO:0005575|cellular_component;GO:0005615|extracellular space;GO:0005794|Golgi apparatus;","GO:0003674|molecular_function;GO:0003677|DNA binding;GO:0003729|mRNA binding;GO:0004866|endopeptidase inhibitor activity;GO:0004867|serine-type endopeptidase inhibitor activity;GO:0019899|enzyme binding;","K23638","SLPI, WFDC4; antileukoproteinase"]
["ENSRNOG00000032708",281,4.30324180736235,23.6420104896487,1731,26.1592918399372,143.719149368615,0.164501464095163,-2.60382767060203,{"v":4.92650661359919e-249,"d":"4.93E-249"},{"v":1.42906512390509e-246,"d":"1.43E-246"},"down","yes","RT1-Bb","protein_coding","chr20:4596559-4607597:-","gi|46237565|emb|CAE83945.1|",1143,{"v":1e-140,"d":"1.00E-140"},"RT1 class II, B beta [Rattus norvegicus]","gi|89214481|gb|AC120734.5|",4049,0,"Rattus norvegicus BAC CH230-220D1 (Children's Hospital Oakland Research Institute Rat (BN/SsNHsd/MCW) BAC library) complete sequence","P29826",418,{"v":2E-132,"d":"2.00E-132"},"Rano class II histocompatibility antigen, B-1 beta chain",".",".",".",".","pfam00969","MHC_II_beta","Class II histocompatibility antigen, beta domain.","GO:0002250|adaptive immune response;GO:0002344|B cell affinity maturation;GO:0002381|immunoglobulin production involved in immunoglobulin mediated immune response;GO:0002503|peptide antigen assembly with MHC class II protein complex;GO:0002504|antigen processing and presentation of peptide or polysaccharide antigen via MHC class II;GO:0002579|positive regulation of antigen processing and presentation;GO:0002827|positive regulation of T-helper 1 type immune response;GO:0006955|immune response;GO:0006959|humoral immune response;GO:0019882|antigen processing and presentation;GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II;GO:0042130|negative regulation of T cell proliferation;GO:0046635|positive regulation of alpha-beta T cell activation;GO:0048002|antigen processing and presentation of peptide antigen;GO:0050832|defense response to fungus;GO:0050852|T cell receptor signaling pathway;GO:0050870|positive regulation of T cell activation;GO:0071315|cellular response to morphine;GO:0071346|cellular response to interferon-gamma;GO:0071385|cellular response to glucocorticoid stimulus;GO:0071549|cellular response to dexamethasone stimulus;","GO:0005769|early endosome;GO:0005771|multivesicular body;GO:0005794|Golgi apparatus;GO:0005886|plasma membrane;GO:0009897|external side of plasma membrane;GO:0009986|cell surface;GO:0016021|integral component of membrane;GO:0042613|MHC class II protein complex;","GO:0015643|toxic substance binding;GO:0023026|MHC class II protein complex binding;GO:0031625|ubiquitin protein ligase binding;GO:0042605|peptide antigen binding;GO:0044877|protein-containing complex binding;GO:1990405|protein antigen binding;","K06752","MHC2; MHC class II antigen"]
["ENSRNOG00000000451",314,19.1161174782787,26.4184743549811,3098,186.119098629641,257.216594306164,0.102709058979045,-3.28336466135426,0,0,"down","yes","RT1-Ba","protein_coding","chr20:4575134-4579744:+","gi|57012346|ref|NP_001008831.1|",1105,{"v":1E-146,"d":"1.00E-146"},"rano class II histocompatibility antigen, B alpha chain precursor [Rattus norvegicus]","gi|89214481|gb|AC120734.5|",705,0,"Rattus norvegicus BAC CH230-220D1 (Children's Hospital Oakland Research Institute Rat (BN/SsNHsd/MCW) BAC library) complete sequence","P20037",380,{"v":8e-129,"d":"8.00E-129"},"Rano class II histocompatibility antigen, B alpha chain",".",".",".",".","pfam00993","MHC_II_alpha","Class II histocompatibility antigen, alpha domain.","GO:0002250|adaptive immune response;GO:0002381|immunoglobulin production involved in immunoglobulin mediated immune response;GO:0002503|peptide antigen assembly with MHC class II protein complex;GO:0019882|antigen processing and presentation;GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II;GO:0034341|response to interferon-gamma;GO:0042130|negative regulation of T cell proliferation;GO:0045582|positive regulation of T cell differentiation;GO:0048002|antigen processing and presentation of peptide antigen;GO:0050870|positive regulation of T cell activation;GO:0071385|cellular response to glucocorticoid stimulus;","GO:0005575|cellular_component;GO:0005764|lysosome;GO:0005886|plasma membrane;GO:0009897|external side of plasma membrane;GO:0016021|integral component of membrane;GO:0042613|MHC class II protein complex;","GO:0023026|MHC class II protein complex binding;GO:0042605|peptide antigen binding;GO:0044877|protein-containing complex binding;","K06752","MHC2; MHC class II antigen"]
["ENSRNOG00000065254",269,3.55743276735169,22.6323872658915,2788,36.3845220910787,231.478329543443,0.0977732443055493,-3.35441646476812,0,0,"down","yes","RT1-CE16","protein_coding","chr20:3257123-3279563:-","gi|57012412|ref|NP_001008838.1|",1715,0,"RT1 class I, locus CE15 precursor [Rattus norvegicus]","gi|1794200|gb|U50449.1|RNU50449",1544,0,"Rattus norvegicus clone 109 class I MHC heavy chain RT1.A(n) antigen precursor (RT1.A(n)) mRNA, complete cds","P16391",544,{"v":9E-175,"d":"9.00E-175"},"RT1 class I histocompatibility antigen, AA alpha chain",".",".",".",".","pfam00129","MHC_I","Class I Histocompatibility antigen, domains alpha 1 and 2.",".",".",".",".","."]
["ENSRNOG00000008837",100,4.90584656830535,8.41352686464368,1090,52.7691311790959,90.4990599721495,0.0929681133398831,-3.42712021134588,{"v":1.34749913098924E-204,"d":"1.35E-204"},{"v":3.07118581755401E-202,"d":"3.07E-202"},"down","yes","Ass1","protein_coding","chr3:14747368-14796903:+","gi|795329564|ref|XP_011826543.1|",2173,0,"PREDICTED: argininosuccinate synthase isoform X2 [Mandrillus leucophaeus]","gi|672044859|ref|XM_006233911.2|",1651,0,"PREDICTED: Rattus norvegicus argininosuccinate synthase 1 (Ass1), transcript variant X1, mRNA","P09034",834,0,"Argininosuccinate synthase","TM1780",479,{"v":2e-164,"d":"2.00E-164"},"COG0137","pfam00764","Arginosuc_synth","Arginosuccinate synthase. This family contains a PP-loop motif.","GO:0000050|urea cycle;GO:0000052|citrulline metabolic process;GO:0000053|argininosuccinate metabolic process;GO:0001822|kidney development;GO:0001889|liver development;GO:0006526|arginine biosynthetic process;GO:0006531|aspartate metabolic process;GO:0006953|acute-phase response;GO:0007494|midgut development;GO:0007568|aging;GO:0007584|response to nutrient;GO:0007623|circadian rhythm;GO:0009410|response to xenobiotic stimulus;GO:0009636|response to toxic substance;GO:0010043|response to zinc ion;GO:0010046|response to mycotoxin;GO:0014075|response to amine;GO:0032355|response to estradiol;GO:0032496|response to lipopolysaccharide;GO:0043200|response to amino acid;GO:0043434|response to peptide hormone;GO:0045429|positive regulation of nitric oxide biosynthetic process;GO:0048545|response to steroid hormone;GO:0051384|response to glucocorticoid;GO:0060416|response to growth hormone;GO:0060539|diaphragm development;GO:0070542|response to fatty acid;GO:0071222|cellular response to lipopolysaccharide;GO:0071230|cellular response to amino acid stimulus;GO:0071242|cellular response to ammonium ion;GO:0071320|cellular response to cAMP;GO:0071346|cellular response to interferon-gamma;GO:0071356|cellular response to tumor necrosis factor;GO:0071377|cellular response to glucagon stimulus;GO:0071400|cellular response to oleic acid;GO:0071418|cellular response to amine stimulus;GO:0071499|cellular response to laminar fluid shear stress;GO:0071549|cellular response to dexamethasone stimulus;GO:1903038|negative regulation of leukocyte cell-cell adhesion;","GO:0005634|nucleus;GO:0005737|cytoplasm;GO:0005739|mitochondrion;GO:0005741|mitochondrial outer membrane;GO:0005764|lysosome;GO:0005783|endoplasmic reticulum;GO:0005829|cytosol;GO:0043005|neuron projection;GO:0043025|neuronal cell body;GO:0043204|perikaryon;GO:0070852|cell body fiber;","GO:0004055|argininosuccinate synthase activity;GO:0005524|ATP binding;GO:0015643|toxic substance binding;GO:0016597|amino acid binding;GO:0042802|identical protein binding;","K01940","argG, ASS1; argininosuccinate synthase [EC:6.3.4.5]"]
["ENSRNOG00000038297",124,3.1816935993163,10.4327733121581,1352,34.2336215400046,112.252045029675,0.0929406079809068,-3.42754710735163,{"v":2.70755703915992e-253,"d":"2.71E-253"},{"v":8.09943130670238e-251,"d":"8.10E-251"},"down","yes","Plekhd1","protein_coding","chr6:100340655-100371941:+","gi|189011673|ref|NP_001121038.1|",1926,0,"pleckstrin homology domain-containing family D member 1 [Rattus norvegicus]","gi|189011672|ref|NM_001127566.1|",3279,0,"Rattus norvegicus pleckstrin homology and coiled-coil domain containing D1 (Plekhd1), mRNA",".",".",".",".",".",".",".",".","pfam00169","PH","PH domain. PH stands for pleckstrin homology.",".",".",".",".","."]