{"text_format":"3","workbook":"xlsx","n_sheets":1,"sheets":["Add File 5"],"read":"whole","date_system":"1900"}

{"sheet":"Add File 5","index":0,"n_rows":109,"n_cols":22,"rows_kept":109,"merged":[[1,1,1,21],[56,1,56,21]]}
[]
[null,"OA cartilage"]
[null,"Patient ID","rs34195470 genotype","Age (years)","Sex","Joint","CpG 1","CpG 2","CpG 3","CpG 4","CpG 5","CpG 6","CpG 7","CpG 8","CpG 9","CpG 10","CpG 11","CpG 12","CpG 13","CpG 14","CpG 15","CpG 16"]
[null,19,"GA",66,"M","Hip",22,35.5,48.5,62,48,48.5,41.5,71.5,36.5,60,44.5,17,46,28.5,18,13.5]
[null,22,"AA",48,"M","Hip",20.5,46,57.5,68.5,58.5,53,44,64.5,40,54.5,34.5,20,37,19.5,16.5,15]
[null,39,"AA",72,"F","Knee",14,21,28,38,27.5,27,null,null,17.5,34,20,7,17.5,9,6,4]
[null,40,"GA",84,"F","Hip",30.5,49,69.5,85.5,75.5,67,64.5,83,55.5,84.5,56,21.5,50.5,31,19,13]
[null,41,"GG",51,"M","Knee",26,37.5,53,73,58.5,54,43.5,76,38,69.5,51.5,13,49.5,27.5,14.5,8.5]
[null,42,"AA",71,"F","Hip",21.5,37,46.5,57.5,49.5,43.5,38.5,62,35,46.5,31,19,29.5,19.5,null,14.5]
[null,45,"AA",93,"M","Knee",13.5,29,29,35.5,27,25,20,47,18,29,21,7.5,19,9.5,7,4.5]
[null,49,"AA",68,"M","Hip",22.5,null,52.5,63,53.5,null,43.5,68.5,37.5,57,40,16.5,38,21,14.5,10.5]
[null,51,"GA",74,"F","Hip",18,30,45,57,48,43.5,45.5,null,32,48.5,29.5,13,27,14.5,10,9]
[null,52,"GG",74,"F","Hip",26,45.5,61.5,79,66.5,61,46,76,45.5,68.5,48.5,15,null,25,14.5,9.5]
[null,53,"GG",55,"F","Hip",31.5,55.5,72,null,null,67,60.5,81,53,80,61,27,58,null,22.5,17.5]
[null,54,"GG",52,"M","Hip",20.5,45.5,54.5,69,55,51.5,39,77,34,66.5,55.5,12,50,28.5,15,7.5]
[null,57,"GA",63,"M","Knee",18.5,null,null,61,null,null,38.5,69,29.5,53,42,11,41,23.5,14,8]
[null,59,"GA",60,"F","Knee",24,53.5,53.5,72,55,54,34.5,60.5,34.5,70,60,17,61,32,19.5,11]
[null,61,"GG",67,"M","Knee",22.5,48.5,56,null,57.5,55.5,45.5,78,35.5,68.5,50,16,48.5,29,15.5,11]
[null,66,"GG",56,"F","Hip",27,null,64,83,65,62.5,51,80,48,78.5,66.5,24.5,64,36,22.5,16.5]
[null,69,"GA",57,"M","Hip",20,null,43.5,63,44.5,null,30.5,74,26.5,56.5,45.5,9.5,45.5,21,10,7.5]
[null,70,"GA",75,"M","Hip",{"$nulls":6},40.5,75.5]
[null,72,"AA",76,"M","Knee",{"$nulls":6},35.5,64.5]
[null,73,"GA",46,"F","Hip",{"$nulls":6},32.5]
[null,76,"GA",65,"F","Knee",19,37,38,50.5,38.5,36,29.5,63.5,23.5,45,36,11.5,36.5,18.5,10.5,7]
[null,77,"GG",71,"F","Knee",20.5,null,null,73,56.5,54.5,39,78,35,71,56,15,57,29.5,16,9]
[null,78,"GA",58,"M","Knee",20.5,null,39.5,52.5,39.5,39,30.5,65,24.5,47,38.5,9.5,38.5,24,13.5,7.5]
[null,79,"GA",65,"M","Knee",23.5,null,48,68.5,52,50.5,41.5,78.5,34,69.5,59,14.5,62.5,32,20.5,14.5]
[null,82,"GA",67,"F","Knee",23.5,null,55,78.5,57.5,55.5,45.5,82,38,73.5,62,17.5,68,36.5,21.5,12]
[null,86,"GA",56,"F","Knee",23.5,null,28.5,73.5,54.5,52,41,73.5,36,66,58,15.5,57.5,33,20.5,12.5]
[null,87,"GG",51,"F","Hip",null,50,60.5,84.5,65.5,65,47.5,82,45,73.5,65,16.5,63,39.5,19.5]
[null,89,"GA",67,"F","Knee",{"$nulls":6},39.5,73]
[null,90,"AA",60,"F","Hip",null,42,49.5,null,48.5,null,37.5,68.5,30.5,54,39.5,12,36,null,10.5,7]
[null,92,"GA",55,"F","Hip",19,44,48,59.5,53,47.5,46,67,35.5,56,38.5,20.5,35,21.5,15.5,14]
[null,96,"GG",61,"F","Hip",25.5,48.5,50,70,53,54,43,77,36,68,55.5,16,59.5,null,16.5,10]
[null,97,"GA",65,"M","Hip",21,null,54.5,74.5,58,null,44.5,75.5,39.5,69,56,19,55,null,18.5,13.5]
[null,98,"GG",49,"M","Hip",21.5,44,46.5,65.5,51,51,null,null,33.5,61.5,49,13,38,25,null,9]
[null,100,"GA",74,"F","Hip",24.5,45,49,66.5,51,49,null,78.5,33,67.5,58,13.5,59.5,32,15,9.5]
[null,103,"AA",70,"F","Knee",null,50,null,69,57,52.5,46.5,78.5,36.5,75.5,58.5,19,60.5,41.5,25,16.5]
[null,104,"GA",70,"F","Knee",null,35,44,57,45.5,44.5,38,62.5,29.5,50,31.5,11,null,18.5,11.5,7.5]
[null,106,"GG",79,"M","Knee",null,51.5,63.5,77.5,66,65,65,82.5,54.5,74.5,63,35.5,63,46,34.5,30.5]
[null,107,"AA",41,"F","Knee",23,41.5,51,null,54.5,55,43.5,81,36,72,61.5,16,65,36,22,13]
[null,108,"AA",72,"M","Knee",17.5,35.5,38.5,48.5,39.5,38.5,31.5,60.5,26.5,45,34.5,12.5,34,21.5,13.5,9]
[null,109,"GG",65,"F","Knee",null,null,52.5,67.5,51,53.5,42,79.5,35,66,54.5,11.5,56,32.5,17.5,10.5]
[null,112,"GA",61,"M","Hip",35,48.5,53.5,70,56.5,54.5,42.5,78.5,34.5,66,55.5,15,55.5,33.5,17.5,11.5]
[null,114,"GA",57,"F","Knee",21.5,39,36.5,51,37,39,32.5,69,24,51,40.5,9.5,40,22,14,8]
[null,115,"GG",69,"M","Knee",22.5,36.5,38,48.5,36.5,36,28,59.5,26,47.5,34,8,32.5,20,11,5.5]
[null,116,"GA",89,"M","Hip",null,null,51.5,72,56,57.5,44,70,37,60,41.5,15,36.5,24.5,13.5,9.5]
[null,117,"GA",82,"M","Hip",19.5,null,48.5,63,49,48,26,64,32.5,59,52,16,50,30,15,11]
[null,126,"AA",66,"F","Hip",17.5,33,37,52.5,37.5,37.5,27,67.5,24,49,36,9,37,20.5,9,5.5]
[null,127,"GG",61,"M","Knee",20.5,null,null,65.5,49.5,49.5,38,74,31,63.5,48.5,9.5,46,29.5,14.5,7]
[null,128,"GG",64,"M","Knee",27.5,null,64,81.5,63,65,50.5,80,42.5,74,65,23.5,66,50,31.5,20.5]
[null,132,"GG",65,"M","Knee",{"$nulls":6},38,75]
[null,135,"GG",69,"F","Hip",{"$nulls":6},41,79.5]
[null,136,"GA",68,"F","Knee",21.5,36,49.5,69,54.5,53.5,39,74,35,65.5,53,14,51.5,34,18.5,10.5]
[]
[]
[null,"Foetal cartilage"]
[null,"Sample ID","rs34195470 genotype","Age (post-conception weeks)","Sex","Joint","CpG 1","CpG 2","CpG 3","CpG 4","CpG 5","CpG 6","CpG 7","CpG 8","CpG 9","CpG 10","CpG 11","CpG 12","CpG 13","CpG 14","CpG 15","CpG 16"]
[null,14377,"AA",14,"M","Tibia",8,22.5,13,18,13.5,16,11.5,null,6.5,17,11.5,3.5,11,6,5,3.5]
[null,14378,"GG",14,"M","Tibia",9.5,24,16.5,23.5,17.5,20.5,16.5,38,8,21.5]
[null,14392,"GA",9,"M","Tibia",10.5,21,17,23,18,19,14.5,35.5,8,22.5,14,3.5,17.5,9,7,6]
[null,14393,"GG",14,"M","Tibia",11.5,30.5,23.5,33.5,24,28,null,null,12,25.5]
[null,14423,"GA",12,"M","Tibia",8.5,19,14.5,22,15.5,17,17.5,36.5,8,23.5,17.5,4,20.5,11,9.5,7.5]
[null,14429,"GG",14,"M","Tibia",9,{"$nulls":3},20.5,20,{"$nulls":9},17.5]
[null,14451,"GA",9,"M","Femur",8.5,null,15.5,20,15,18,12.5,32,8.5,20.5,13.5,4,16,7.5,6,5]
[null,14453,"AA",12,"F","Femur",7,20.5,15.5,22,16.5,18,13.5,32.5,7.5,18.5]
[null,14460,"GA",9,"F","Tibia",9,15.5,20,26.5,19.5,23,12,33.5,8,19,14.5,6,18.5,9.5,7,6.5]
[null,14464,"GA",16,"M","Tibia",15.5,24,26,34.5,27.5,32,20,42.5,12,26,15,5.5,19,11,7.5,6]
[null,14467,"AA",10,"M","Tibia",13,23,22,31,21,23.5,18.5,39,12,23.5,17.5,9.5,22.5,11.5,9.5,10]
[null,14471,"GG",9,"F","Femur and tibia",9,24,18.5,24.5,19,20,17.5,40.5,8.5,27,18,5,22,10.5,8.5,9.5]
[null,14475,"GA",16,"M","Tibia",12,23,19.5,26,19.5,21,22,null,13.5,25,20.5,6,22.5,12,10.5,8]
[null,14492,"GA",12,"F","Tibia",10,25,20,26.5,22,23.5,17.5,41,10,25.5,14.5,4.5,18.5,10,7.5,5.5]
[null,14501,"GA",16,"M","Tibia",11.5,30,27.5,34.5,26.5,31.5,25,50.5,14.5,31,20,5.5,24.5,13,10.5,8]
[null,14512,"GG",10,"M","Tibia",11.5,26.5,20.5,29.5,23,null,20,43.5,11.5,29.5,18.5,4.5,25,14,10,8.5]
[null,14513,"GG",12,"F","Femur and tibia",10.5,28,21.5,28,21,26.5,19,43.5,11,24.5,17.5,5.5,22.5,12,9,8]
[null,14516,"GG",15,"M","Tibia",8.5,21,17.5,23,17,17.5,18.5,40,9,23.5,18.5,5.5,22,10,7,7.5]
[null,14521,"GA",12,"M","Tibia",6,18.5,11,17,10.5,14.5,12,30,6,17,11.5,3,14,6,5.5,4.5]
[null,14523,"GA",15,"F","Tibia",8.5,23.5,16,23,16.5,19.5,16,42.5,9,24.5,16.5,4,20,10.5,7.5,6]
[null,14524,"GG",15,"F","Tibia",7,20.5,13.5,18,14,16,12,31.5,7.5,17.5,10.5,3.5,13.5,6,4.5,3]
[null,14525,"GG",10,"M","Tibia",18,26.5,25.5,32,26,26,23,46,14,33,19.5,6,25.5,14.5,10,9.5]
[null,14532,"GA",11,"F","Tibia",12.5,26,25.5,30,25,28,19.5,40,11,25.5,15,4.5,20,10.5,7,5.5]
[null,14541,"AA",11,"M","Tibia",8.5,24,18.5,23,18.5,21.5,14,35.5,8,21,12.5,4.5,16.5,7.5,6,4.5]
[null,14544,"GG",13,"M","Tibia",9.5,25.5,20.5,29.5,22.5,26.5,20,40,10.5,27]
[null,14555,"GG",9,"M","Femur and tibia",13,25.5,22.5,27,22.5,23.5,19,39.5,10,23.5,12.5,3.5,18,10,6,5.5]
[null,14562,"GG",9,"F","Tibia",11.5,30.5,27.5,33,26.5,27.5,21,44.5,12,28,22,8,26,15.5,10,9]
[null,14576,"GA",8,"M","Femur and tibia",8,24.5,14.5,19.5,14,14.5,10,28,6.5,18,12,3,13.5,7,5,4.5]
[null,14580,"GA",9,"M","Femur and tibia",9,26,18,24,19,22.5,16,35.5,9,23.5,11,3.5,14,7,5.5,4]
[null,14586,"GA",13,"F","Femur and tibia",10,21,17,23,18,21.5,14,36,9,21,14.5,4.5,17,9,7,5.5]
[null,14600,"GA",8,"M","Tibia",13,19,21,24.5,19.5,21,17,34.5,10,24.5]
[null,14601,"GA",10,"M","Femur and tibia",15.5,14,16,22,16.5,18.5,19,38,null,null,10.5,2.5,14.5,7.5,5.5,3.5]
[null,14604,"GA",14,"F","Tibia",10.5,25.5,22,29.5,23.5,23.5,18.5,41.5,15,22,16.5,5,21.5,11.5,9,7.5]
[null,14617,"AA",13,"F","Femur and tibia",7.5,24.5,17,23,17.5,20.5,15,35,8.5,20.5,14,4,15.5,7.5,6,4.5]
[null,14619,"GG",16,"M","Femur and tibia",null,null,14,20,14.5,16,15,32,7.5,19]
[null,14628,"GA",17,"F","Femur and tibia",11,22,17,24.5,18,21.5,19,null,9.5,22,15,4,19,9.5,5.5,6.5]
[null,14684,"GA",14,"F","Femur",10,25.5,21.5,null,24.5,23.5,14.5,36.5,8,22,14,4,16.5,8.5,7,5]
[null,14703,"GA",12,"F","Femur and tibia",9,19,18,22.5,18.5,20,null,null,8.5,20,12,3.5,15,8.5,5.5,4.5]
[null,14713,"GG",16,"F","Femur and tibia",19.5,26,23.5,30.5,25.5,28,22.5,45.5,13,30,21,7.5,27.5,14.5,11,10]
[null,14715,"GA",12,"M","Femur and tibia",{"$nulls":6},22.5,41.5]
[null,14716,"AA",10,"M","Femur and tibia",14,19.5,21,27,19.5,20.5,19,36.5,9,null,15,3.5,20,11,8,8]
[null,14720,"GG",15,"F","Femur and tibia",10,25.5,15,20,17,16.5,17,37.5,9.5,25.5,18.5,5,22.5,14.5,9.5,7.5]
[null,14721,"GA",10,"F","Femur and tibia",9,20,16.5,21,16.5,19,23,44.5,9.5,23,16,4.5,26,11,6.5,6]
[null,14722,"GA",17,"M","Femur and tibia",11.5,24,23,30.5,23.5,27.5,23.5,46.5,13.5,31,20.5,6.5,24,11,8.5,7]
[null,14728,"GA",16,"M","Femur and tibia",18.5,17.5,21.5,29,20,26,17,35.5,10.5,24.5]
[null,14746,"GA",16,"F","Femur and tibia",12,17.5,15.5,20.5,15.5,19,15.5,null,8.5,18.5,10,4,14,6.5,6,4.5]
[null,14748,"GA",10,"F","Femur and tibia",null,null,17.5,25,18,20,25.5,44]
[null,14831,"GG",9,"F","Femur and tibia",null,null,20,28,21,21.5]
[]
[]
["Additional file 5. b-values for the 16 CpGs in cartilage DNA from the OA patients and the foetal samples."]