{"text_format":"3","workbook":"xls","n_sheets":2,"sheets":["Supplementary table 1","Supplementary table 2"],"read":"whole","date_system":"1900","formulas":"cached_only"}

{"sheet":"Supplementary table 1","index":0,"n_rows":407,"n_cols":5,"rows_kept":407,"flags":["formulas_cached_only"]}
["ONTOLOGY","ID","Description","pvalue","Count"]
["BP","GO:0006958","complement activation, classical pathway",{"v":6.37266750740285e-114,"d":"6.37E-114"},80]
["BP","GO:0002455","humoral immune response mediated by circulating immunoglobulin",{"v":1.96326297633522e-111,"d":"1.96E-111"},81]
["BP","GO:0006956","complement activation",{"v":3.777174283668e-102,"d":"3.78E-102"},80]
["BP","GO:0072376","protein activation cascade",{"v":1.15506898450301e-96,"d":"1.16E-96"},80]
["BP","GO:0016064","immunoglobulin mediated immune response",{"v":4.85079391687177e-96,"d":"4.85E-96"},82]
["BP","GO:0019724","B cell mediated immunity",{"v":1.90545107846112e-95,"d":"1.91E-95"},82]
["BP","GO:0006959","humoral immune response",{"v":7.32667873444643e-88,"d":"7.33E-88"},90]
["BP","GO:0002460","adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains",{"v":2.95090206044351e-87,"d":"2.95E-87"},90]
["BP","GO:0002449","lymphocyte mediated immunity",{"v":7.9314353996927e-87,"d":"7.93E-87"},89]
["BP","GO:0002429","immune response-activating cell surface receptor signaling pathway",{"v":9.28825796314458e-83,"d":"9.29E-83"},95]
["BP","GO:0006909","phagocytosis",{"v":2.27964169371002e-80,"d":"2.28E-80"},86]
["BP","GO:0006910","phagocytosis, recognition",{"v":5.58536004259011e-69,"d":"5.59E-69"},49]
["BP","GO:0002920","regulation of humoral immune response",{"v":3.27435492054426e-66,"d":"3.27E-66"},55]
["BP","GO:0050853","B cell receptor signaling pathway",{"v":1.43188018919515e-65,"d":"1.43E-65"},54]
["BP","GO:0030449","regulation of complement activation",{"v":2.43672952802138e-65,"d":"2.44E-65"},52]
["BP","GO:2000257","regulation of protein activation cascade",{"v":4.36474485330215e-65,"d":"4.36E-65"},52]
["BP","GO:0002377","immunoglobulin production",{"v":4.65732357488607e-62,"d":"4.66E-62"},59]
["BP","GO:0002433","immune response-regulating cell surface receptor signaling pathway involved in phagocytosis",{"v":1.12867267245667e-61,"d":"1.13E-61"},53]
["BP","GO:0038096","Fc-gamma receptor signaling pathway involved in phagocytosis",{"v":1.12867267245667e-61,"d":"1.13E-61"},53]
["BP","GO:0038094","Fc-gamma receptor signaling pathway",{"v":4.48205618962415e-61,"d":"4.48E-61"},53]
["BP","GO:0050871","positive regulation of B cell activation",{"v":4.48205618962415e-61,"d":"4.48E-61"},53]
["BP","GO:0002431","Fc receptor mediated stimulatory signaling pathway",{"v":1.71449242752225e-60,"d":"1.71E-60"},53]
["BP","GO:0006911","phagocytosis, engulfment",{"v":3.17634214682886e-59,"d":"3.18E-59"},49]
["BP","GO:0002673","regulation of acute inflammatory response",{"v":5.77645851561097e-58,"d":"5.78E-58"},53]
["BP","GO:0099024","plasma membrane invagination",{"v":2.77194054625261e-57,"d":"2.77E-57"},49]
["BP","GO:0050864","regulation of B cell activation",{"v":3.67155903589249e-57,"d":"3.67E-57"},55]
["BP","GO:0051249","regulation of lymphocyte activation",{"v":9.45803812662895e-57,"d":"9.46E-57"},76]
["BP","GO:0051251","positive regulation of lymphocyte activation",{"v":7.57110835839999e-56,"d":"7.57E-56"},66]
["BP","GO:0010324","membrane invagination",{"v":1.05153097004181e-55,"d":"1.05E-55"},49]
["BP","GO:0002440","production of molecular mediator of immune response",{"v":5.17446186261603e-55,"d":"5.17E-55"},62]
["BP","GO:0070613","regulation of protein processing",{"v":1.16989019763878e-54,"d":"1.17E-54"},53]
["BP","GO:1903317","regulation of protein maturation",{"v":2.27956632462417e-54,"d":"2.28E-54"},53]
["BP","GO:0002526","acute inflammatory response",{"v":8.00581048128882e-54,"d":"8.01E-54"},56]
["BP","GO:0002696","positive regulation of leukocyte activation",{"v":2.95118067412759e-53,"d":"2.95E-53"},67]
["BP","GO:0008037","cell recognition",{"v":5.61052341795627e-53,"d":"5.61E-53"},55]
["BP","GO:0050867","positive regulation of cell activation",{"v":3.59938171225592e-52,"d":"3.60E-52"},67]
["BP","GO:0050851","antigen receptor-mediated signaling pathway",{"v":3.69641131925674e-52,"d":"3.70E-52"},62]
["BP","GO:0042113","B cell activation",{"v":4.64307518359489e-50,"d":"4.64E-50"},60]
["BP","GO:0050900","leukocyte migration",{"v":7.7276099307132e-50,"d":"7.73E-50"},71]
["BP","GO:0038095","Fc-epsilon receptor signaling pathway",{"v":1.31854791002489e-48,"d":"1.32E-48"},48]
["BP","GO:0038093","Fc receptor signaling pathway",{"v":3.10432386775182e-47,"d":"3.10E-47"},53]
["BP","GO:0042742","defense response to bacterium",{"v":7.94725700826494e-46,"d":"7.95E-46"},58]
["BP","GO:0002697","regulation of immune effector process",{"v":3.0766248707958e-44,"d":"3.08E-44"},64]
["BP","GO:0006898","receptor-mediated endocytosis",{"v":6.20912490190819e-42,"d":"6.21E-42"},54]
["BP","GO:0016485","protein processing",{"v":4.85914226267711e-41,"d":"4.86E-41"},54]
["BP","GO:0051604","protein maturation",{"v":1.13514587154643e-37,"d":"1.14E-37"},55]
["BP","GO:0050727","regulation of inflammatory response",{"v":3.84698679610273e-36,"d":"3.85E-36"},58]
["BP","GO:0042110","T cell activation",{"v":2.00250737581683e-12,"d":"2.00E-12"},31]
["BP","GO:0030098","lymphocyte differentiation",{"v":2.57497012948702e-12,"d":"2.57E-12"},27]
["BP","GO:0050863","regulation of T cell activation",{"v":4.55040606234912e-11,"d":"4.55E-11"},24]
["BP","GO:0030217","T cell differentiation",{"v":6.37199904610353e-11,"d":"6.37E-11"},21]
["BP","GO:0043368","positive T cell selection",{"v":1.05407914557026e-09,"d":"1.05E-09"},9]
["BP","GO:0045058","T cell selection",{"v":1.26279283545426e-09,"d":"1.26E-09"},10]
["BP","GO:0046631","alpha-beta T cell activation",{"v":1.60366279725561e-08,"d":"1.60E-08"},14]
["BP","GO:0007159","leukocyte cell-cell adhesion",{"v":2.90522667925901e-08,"d":"2.91E-08"},21]
["BP","GO:0050870","positive regulation of T cell activation",{"v":5.20352778406738e-08,"d":"5.20E-08"},16]
["BP","GO:1903037","regulation of leukocyte cell-cell adhesion",{"v":1.29105407208622e-07,"d":"1.29E-07"},19]
["BP","GO:1903039","positive regulation of leukocyte cell-cell adhesion",{"v":1.49590459257454e-07,"d":"1.50E-07"},16]
["BP","GO:0046632","alpha-beta T cell differentiation",{"v":2.75198315956447e-07,"d":"2.75E-07"},11]
["BP","GO:0045061","thymic T cell selection",{"v":4.2658806378528e-07,"d":"4.27E-07"},6]
["BP","GO:0045059","positive thymic T cell selection",{"v":7.67308465088949e-07,"d":"7.67E-07"},5]
["BP","GO:0070268","cornification",{"v":7.88073704557555e-07,"d":"7.88E-07"},11]
["BP","GO:0022409","positive regulation of cell-cell adhesion",{"v":1.2307505401521e-06,"d":"1.23E-06"},16]
["BP","GO:0022407","regulation of cell-cell adhesion",{"v":2.2995364024534e-06,"d":"2.30E-06"},20]
["BP","GO:0050670","regulation of lymphocyte proliferation",{"v":2.53931750909159e-06,"d":"2.54E-06"},14]
["BP","GO:0032944","regulation of mononuclear cell proliferation",{"v":2.68635903244515e-06,"d":"2.69E-06"},14]
["BP","GO:0046651","lymphocyte proliferation",{"v":2.85307802353437e-06,"d":"2.85E-06"},16]
["BP","GO:0032943","mononuclear cell proliferation",{"v":3.1355198979637e-06,"d":"3.14E-06"},16]
["BP","GO:0070663","regulation of leukocyte proliferation",{"v":5.41992543947876e-06,"d":"5.42E-06"},14]
["BP","GO:0045580","regulation of T cell differentiation",{"v":6.61745506645266e-06,"d":"6.62E-06"},11]
["BP","GO:0045619","regulation of lymphocyte differentiation",{"v":7.73359046526104e-06,"d":"7.73E-06"},12]
["BP","GO:0033077","T cell differentiation in thymus",{"v":8.3489225148977e-06,"d":"8.35E-06"},8]
["BP","GO:0046634","regulation of alpha-beta T cell activation",{"v":9.08341873747699e-06,"d":"9.08E-06"},9]
["BP","GO:0070661","leukocyte proliferation",{"v":9.1057844389077e-06,"d":"9.11E-06"},16]
["BP","GO:0043367","CD4-positive, alpha-beta T cell differentiation",{"v":1.26713693423273e-05,"d":"1.27E-05"},8]
["BP","GO:0045060","negative thymic T cell selection",{"v":1.38099142377689e-05,"d":"1.38E-05"},4]
["BP","GO:0042129","regulation of T cell proliferation",{"v":1.97825131787895e-05,"d":"1.98E-05"},11]
["BP","GO:0043383","negative T cell selection",{"v":2.04759126628678e-05,"d":"2.05E-05"},4]
["BP","GO:0031424","keratinization",{"v":2.83251941350763e-05,"d":"2.83E-05"},13]
["BP","GO:0045785","positive regulation of cell adhesion",{"v":3.05687248782395e-05,"d":"3.06E-05"},18]
["BP","GO:0097028","dendritic cell differentiation",{"v":3.18412277945413e-05,"d":"3.18E-05"},6]
["BP","GO:0046635","positive regulation of alpha-beta T cell activation",{"v":3.35272198113967e-05,"d":"3.35E-05"},7]
["BP","GO:0001771","immunological synapse formation",{"v":4.04576928828124e-05,"d":"4.05E-05"},4]
["BP","GO:0001773","myeloid dendritic cell activation",{"v":4.89228085297723e-05,"d":"4.89E-05"},5]
["BP","GO:0019731","antibacterial humoral response",{"v":5.41303111996498e-05,"d":"5.41E-05"},6]
["BP","GO:0035710","CD4-positive, alpha-beta T cell activation",{"v":6.23444122293641e-05,"d":"6.23E-05"},8]
["BP","GO:0042102","positive regulation of T cell proliferation",{"v":7.83908526430063e-05,"d":"7.84E-05"},8]
["BP","GO:0042098","T cell proliferation",{"v":8.96480232860487e-05,"d":"8.96E-05"},11]
["BP","GO:0043011","myeloid dendritic cell differentiation",0.000118079424680507,4]
["BP","GO:0050671","positive regulation of lymphocyte proliferation",0.000129801049063159,9]
["BP","GO:0032946","positive regulation of mononuclear cell proliferation",0.000137616923598538,9]
["BP","GO:0002363","alpha-beta T cell lineage commitment",0.000147847454121564,4]
["BP","GO:0046641","positive regulation of alpha-beta T cell proliferation",0.000147847454121564,4]
["BP","GO:0031295","T cell costimulation",0.000165986977036516,6]
["BP","GO:0030216","keratinocyte differentiation",0.000176302778343741,14]
["BP","GO:0043369","CD4-positive or CD8-positive, alpha-beta T cell lineage commitment",0.000182685253817174,4]
["BP","GO:0031294","lymphocyte costimulation",0.00018325777369816,6]
["BP","GO:0070665","positive regulation of leukocyte proliferation",0.000215485198529863,9]
["BP","GO:0045582","positive regulation of T cell differentiation",0.000217897401649991,7]
["BP","GO:2000106","regulation of leukocyte apoptotic process",0.000217897401649991,7]
["BP","GO:0003094","glomerular filtration",0.00022307754263,4]
["BP","GO:0032609","interferon-gamma production",0.000263097315160391,8]
["BP","GO:0097205","renal filtration",0.000269519613988933,4]
["BP","GO:0019835","cytolysis",0.000283710902516119,5]
["BP","GO:0046637","regulation of alpha-beta T cell differentiation",0.000318850976032582,6]
["BP","GO:0001768","establishment of T cell polarity",0.000347606263419712,3]
["BP","GO:0097048","dendritic cell apoptotic process",0.000347606263419712,3]
["BP","GO:2000668","regulation of dendritic cell apoptotic process",0.000347606263419712,3]
["BP","GO:0002407","dendritic cell chemotaxis",0.000382579478448396,4]
["BP","GO:0050901","leukocyte tethering or rolling",0.000450229413209754,4]
["BP","GO:0045621","positive regulation of lymphocyte differentiation",0.000468601764208931,7]
["BP","GO:0001767","establishment of lymphocyte polarity",0.00047277989436294,3]
["BP","GO:0002604","regulation of dendritic cell antigen processing and presentation",0.00047277989436294,3]
["BP","GO:0043588","skin development",0.00049342222583562,16]
["BP","GO:0042100","B cell proliferation",0.000499641268538038,7]
["BP","GO:0002360","T cell lineage commitment",0.000525991106037468,4]
["BP","GO:2000107","negative regulation of leukocyte apoptotic process",0.000608371421622022,5]
["BP","GO:0036336","dendritic cell migration",0.000610394478481397,4]
["BP","GO:0002468","dendritic cell antigen processing and presentation",0.000623547888262964,3]
["BP","GO:0030183","B cell differentiation",0.00070948486036112,8]
["BP","GO:1902105","regulation of leukocyte differentiation",0.000719941911537769,12]
["BP","GO:0032649","regulation of interferon-gamma production",0.000721963713960245,7]
["BP","GO:0001895","retina homeostasis",0.00076013007878878,6]
["BP","GO:0045086","positive regulation of interleukin-2 biosynthetic process",0.000801841667049956,3]
["BP","GO:0071887","leukocyte apoptotic process",0.000859184938399638,7]
["BP","GO:0009913","epidermal cell differentiation",0.000873939668977296,14]
["BP","GO:0032743","positive regulation of interleukin-2 production",0.000920802607872441,4]
["BP","GO:0046640","regulation of alpha-beta T cell proliferation",0.000920802607872441,4]
["BP","GO:0046330","positive regulation of JNK cascade",0.00109404136873913,8]
["BP","GO:0072676","lymphocyte migration",0.00125972162857732,7]
["BP","GO:0046633","alpha-beta T cell proliferation",0.00132830390330709,4]
["BP","GO:0001912","positive regulation of leukocyte mediated cytotoxicity",0.00136107474305819,5]
["BP","GO:0008544","epidermis development",0.00144542005089723,16]
["BP","GO:0002295","T-helper cell lineage commitment",0.00151969817637066,3]
["BP","GO:0042093","T-helper cell differentiation",0.00159436502907269,5]
["BP","GO:0043373","CD4-positive, alpha-beta T cell lineage commitment",0.00182543885006364,3]
["BP","GO:0060263","regulation of respiratory burst",0.00182543885006364,3]
["BP","GO:1903706","regulation of hemopoiesis",0.00183376220432168,16]
["BP","GO:0002294","CD4-positive, alpha-beta T cell differentiation involved in immune response",0.00185577002945491,5]
["BP","GO:0018149","peptide cross-linking",0.00185577002945491,5]
["BP","GO:0070098","chemokine-mediated signaling pathway",0.00187551582272139,6]
["BP","GO:0002287","alpha-beta T cell activation involved in immune response",0.00199762313151903,5]
["BP","GO:0002293","alpha-beta T cell differentiation involved in immune response",0.00199762313151903,5]
["BP","GO:0030888","regulation of B cell proliferation",0.00199762313151903,5]
["BP","GO:0045730","respiratory burst",0.00204771498467641,4]
["BP","GO:0036148","phosphatidylglycerol acyl-chain remodeling",0.00216691073514026,3]
["BP","GO:0019730","antimicrobial humoral response",0.00216896589577874,7]
["BP","GO:0045076","regulation of interleukin-2 biosynthetic process",0.00254548510033127,3]
["BP","GO:0032729","positive regulation of interferon-gamma production",0.00264510061311418,5]
["BP","GO:0072678","T cell migration",0.00264510061311418,5]
["BP","GO:0034341","response to interferon-gamma",0.00276517086257355,9]
["BP","GO:0002577","regulation of antigen processing and presentation",0.00296244977912787,3]
["BP","GO:0010560","positive regulation of glycoprotein biosynthetic process",0.00296244977912787,3]
["BP","GO:0050852","T cell receptor signaling pathway",0.00305501754836943,9]
["BP","GO:1990868","response to chemokine",0.00306634094654476,6]
["BP","GO:1990869","cellular response to chemokine",0.00306634094654476,6]
["BP","GO:0002292","T cell differentiation involved in immune response",0.0032216959863746,5]
["BP","GO:0031343","positive regulation of cell killing",0.0032216959863746,5]
["BP","GO:0010559","regulation of glycoprotein biosynthetic process",0.00327730215031585,4]
["BP","GO:0001906","cell killing",0.00343261925489819,8]
["BP","GO:0032496","response to lipopolysaccharide",0.0036324050613911,12]
["BP","GO:0001819","positive regulation of cytokine production",0.00370629843998366,15]
["BP","GO:0061756","leukocyte adhesion to vascular endothelial cell",0.00388496138460209,4]
["BP","GO:0042094","interleukin-2 biosynthetic process",0.0039163000613687,3]
["BP","GO:0032874","positive regulation of stress-activated MAPK cascade",0.00395810838894781,8]
["BP","GO:0070304","positive regulation of stress-activated protein kinase signaling cascade",0.00409869841241154,8]
["BP","GO:0009988","cell-cell recognition",0.00437579925455371,5]
["BP","GO:0032753","positive regulation of interleukin-4 production",0.0044553676633756,3]
["BP","GO:0034695","response to prostaglandin E",0.0044553676633756,3]
["BP","GO:0007157","heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules",0.00456465221181974,4]
["BP","GO:0002286","T cell activation involved in immune response",0.0047476188666262,6]
["BP","GO:0002237","response to molecule of bacterial origin",0.00492792361378188,12]
["BP","GO:0043370","regulation of CD4-positive, alpha-beta T cell differentiation",0.00493267833183813,4]
["BP","GO:0046638","positive regulation of alpha-beta T cell differentiation",0.00493267833183813,4]
["BP","GO:0001909","leukocyte mediated cytotoxicity",0.00496928697209946,6]
["BP","GO:0031579","membrane raft organization",0.00503719454693662,3]
["BP","GO:0042832","defense response to protozoan",0.00503719454693662,3]
["BP","GO:0090023","positive regulation of neutrophil chemotaxis",0.00503719454693662,3]
["BP","GO:1903020","positive regulation of glycoprotein metabolic process",0.00503719454693662,3]
["BP","GO:0071346","cellular response to interferon-gamma",0.00519364999208251,8]
["BP","GO:0002285","lymphocyte activation involved in immune response",0.00536672852692544,8]
["BP","GO:1902107","positive regulation of leukocyte differentiation",0.00542709416551217,7]
["BP","GO:0001562","response to protozoan",0.00566268979244484,3]
["BP","GO:0002534","cytokine production involved in inflammatory response",0.00572735321022182,4]
["BP","GO:1903018","regulation of glycoprotein metabolic process",0.00572735321022182,4]
["BP","GO:0001910","regulation of leukocyte mediated cytotoxicity",0.00579788989601024,5]
["BP","GO:0046328","regulation of JNK cascade",0.00610347182064416,8]
["BP","GO:1903708","positive regulation of hemopoiesis",0.00610347182064416,8]
["BP","GO:0007160","cell-matrix adhesion",0.0061545378573936,9]
["BP","GO:0036152","phosphatidylethanolamine acyl-chain remodeling",0.00633269396893275,3]
["BP","GO:0071624","positive regulation of granulocyte chemotaxis",0.00633269396893275,3]
["BP","GO:0001894","tissue homeostasis",0.00650921979750887,9]
["BP","GO:0032673","regulation of interleukin-4 production",0.00704798140523918,3]
["BP","GO:0036151","phosphatidylcholine acyl-chain remodeling",0.00704798140523918,3]
["BP","GO:0032964","collagen biosynthetic process",0.0075632634471111,4]
["BP","GO:0050704","regulation of interleukin-1 secretion",0.0075632634471111,4]
["BP","GO:0097305","response to alcohol",0.00766807315124335,9]
["BP","GO:0007204","positive regulation of cytosolic calcium ion concentration",0.00772783623981543,11]
["BP","GO:0032663","regulation of interleukin-2 production",0.0080760064630182,4]
["BP","GO:1902624","positive regulation of neutrophil migration",0.00861718539311997,3]
["BP","GO:0001942","hair follicle development",0.00870522017321971,5]
["BP","GO:0032760","positive regulation of tumor necrosis factor production",0.00870522017321971,5]
["BP","GO:0060402","calcium ion transport into cytosol",0.00887043900376723,7]
["BP","GO:0072610","interleukin-12 secretion",0.00893488550386325,2]
["BP","GO:0043372","positive regulation of CD4-positive, alpha-beta T cell differentiation",0.00947233903592525,3]
["BP","GO:0090022","regulation of neutrophil chemotaxis",0.00947233903592525,3]
["BP","GO:0022404","molting cycle process",0.00956506754401677,5]
["BP","GO:0022405","hair cycle process",0.00956506754401677,5]
["BP","GO:0098773","skin epidermis development",0.00956506754401677,5]
["BP","GO:1903557","positive regulation of tumor necrosis factor superfamily cytokine production",0.00956506754401677,5]
["BP","GO:0034694","response to prostaglandin",0.0103752542680311,3]
["BP","GO:0046471","phosphatidylglycerol metabolic process",0.0103752542680311,3]
["BP","GO:0060333","interferon-gamma-mediated signaling pathway",0.0109617008196903,5]
["BP","GO:0071222","cellular response to lipopolysaccharide",0.0109956261748016,8]
["BP","GO:0043552","positive regulation of phosphatidylinositol 3-kinase activity",0.0113264062953579,3]
["BP","GO:0045123","cellular extravasation",0.012309302105087,4]
["BP","GO:0050701","interleukin-1 secretion",0.012309302105087,4]
["BP","GO:2000514","regulation of CD4-positive, alpha-beta T cell activation",0.012309302105087,4]
["BP","GO:0032633","interleukin-4 production",0.012326216534563,3]
["BP","GO:0006527","arginine catabolic process",0.0128537145228501,2]
["BP","GO:0038110","interleukin-2-mediated signaling pathway",0.0128537145228501,2]
["BP","GO:0072540","T-helper 17 cell lineage commitment",0.0128537145228501,2]
["BP","GO:0031640","killing of cells of other organism",0.0130101342226433,4]
["BP","GO:0032623","interleukin-2 production",0.0130101342226433,4]
["BP","GO:0044364","disruption of cells of other organism",0.0130101342226433,4]
["BP","GO:0071219","cellular response to molecule of bacterial origin",0.0132534767744001,8]
["BP","GO:0060401","cytosolic calcium ion transport",0.0133019079690213,7]
["BP","GO:0007254","JNK cascade",0.0139567090160599,8]
["BP","GO:0002701","negative regulation of production of molecular mediator of immune response",0.0144732396633254,3]
["BP","GO:0032735","positive regulation of interleukin-12 production",0.0144732396633254,3]
["BP","GO:0045622","regulation of T-helper cell differentiation",0.0144732396633254,3]
["BP","GO:0060326","cell chemotaxis",0.0146843906452447,10]
["BP","GO:0002699","positive regulation of immune effector process",0.0146867975782368,8]
["BP","GO:0031341","regulation of cell killing",0.0147476870236224,5]
["BP","GO:0031274","positive regulation of pseudopodium assembly",0.0150449641329955,2]
["BP","GO:0035723","interleukin-15-mediated signaling pathway",0.0150449641329955,2]
["BP","GO:0071350","cellular response to interleukin-15",0.0150449641329955,2]
["BP","GO:0071352","cellular response to interleukin-2",0.0150449641329955,2]
["BP","GO:0019722","calcium-mediated signaling",0.015444291280808,8]
["BP","GO:0090218","positive regulation of lipid kinase activity",0.0156210432091059,3]
["BP","GO:1902622","regulation of neutrophil migration",0.0156210432091059,3]
["BP","GO:2000516","positive regulation of CD4-positive, alpha-beta T cell activation",0.0156210432091059,3]
["BP","GO:0031589","cell-substrate adhesion",0.0158639671903493,11]
["BP","GO:0051480","regulation of cytosolic calcium ion concentration",0.0167819611569826,11]
["BP","GO:0002700","regulation of production of molecular mediator of immune response",0.0168099672550322,6]
["BP","GO:0042108","positive regulation of cytokine biosynthetic process",0.016893991836902,4]
["BP","GO:0031272","regulation of pseudopodium assembly",0.0173842095148577,2]
["BP","GO:0043374","CD8-positive, alpha-beta T cell differentiation",0.0173842095148577,2]
["BP","GO:0051712","positive regulation of killing of cells of other organism",0.0173842095148577,2]
["BP","GO:0070669","response to interleukin-2",0.0173842095148577,2]
["BP","GO:0070672","response to interleukin-15",0.0173842095148577,2]
["BP","GO:1901626","regulation of postsynaptic membrane organization",0.0173842095148577,2]
["BP","GO:0030595","leukocyte chemotaxis",0.0178866081187781,8]
["BP","GO:0002707","negative regulation of lymphocyte mediated immunity",0.0180663593429794,3]
["BP","GO:0050766","positive regulation of phagocytosis",0.0195371507410442,4]
["BP","GO:0002456","T cell mediated immunity",0.0200451902792866,5]
["BP","GO:0002532","production of molecular mediator involved in inflammatory response",0.0214332826796426,4]
["BP","GO:0030890","positive regulation of B cell proliferation",0.0221106660958554,3]
["BP","GO:0051668","localization within membrane",0.0221472627702341,6]
["BP","GO:0002643","regulation of tolerance induction",0.022487663349418,2]
["BP","GO:0031269","pseudopodium assembly",0.022487663349418,2]
["BP","GO:0033033","negative regulation of myeloid cell apoptotic process",0.022487663349418,2]
["BP","GO:0002706","regulation of lymphocyte mediated immunity",0.022803170348876,6]
["BP","GO:0002639","positive regulation of immunoglobulin production",0.0235593863993585,3]
["BP","GO:0071216","cellular response to biotic stimulus",0.0235824808676846,8]
["BP","GO:0032872","regulation of stress-activated MAPK cascade",0.0241085419171794,8]
["BP","GO:0042303","molting cycle",0.0247456098871597,5]
["BP","GO:0042633","hair cycle",0.0247456098871597,5]
["BP","GO:0070302","regulation of stress-activated protein kinase signaling cascade",0.0251852859994016,8]
["BP","GO:0006590","thyroid hormone generation",0.0252426266159986,2]
["BP","GO:0031268","pseudopodium organization",0.0252426266159986,2]
["BP","GO:0032966","negative regulation of collagen biosynthetic process",0.0252426266159986,2]
["BP","GO:0036149","phosphatidylinositol acyl-chain remodeling",0.0252426266159986,2]
["BP","GO:0045187","regulation of circadian sleep/wake cycle, sleep",0.0252426266159986,2]
["BP","GO:0050665","hydrogen peroxide biosynthetic process",0.0252426266159986,2]
["BP","GO:0051709","regulation of killing of cells of other organism",0.0252426266159986,2]
["BP","GO:0045807","positive regulation of endocytosis",0.0255573048120707,6]
["BP","GO:0032965","regulation of collagen biosynthetic process",0.0266076898913108,3]
["BP","GO:0051489","regulation of filopodium assembly",0.0266076898913108,3]
["BP","GO:0071622","regulation of granulocyte chemotaxis",0.0266076898913108,3]
["BP","GO:0032963","collagen metabolic process",0.0273401237686989,5]
["BP","GO:0048871","multicellular organismal homeostasis",0.0274329087990564,13]
["BP","GO:0010713","negative regulation of collagen metabolic process",0.0281270911011059,2]
["BP","GO:0032309","icosanoid secretion",0.0282071272436318,3]
["BP","GO:0002715","regulation of natural killer cell mediated immunity",0.0298566022458512,3]
["BP","GO:1900015","regulation of cytokine production involved in inflammatory response",0.0298566022458512,3]
["BP","GO:0002544","chronic inflammatory response",0.0311366918070793,2]
["BP","GO:0002710","negative regulation of T cell mediated immunity",0.0311366918070793,2]
["BP","GO:0002922","positive regulation of humoral immune response",0.0311366918070793,2]
["BP","GO:0045063","T-helper 1 cell differentiation",0.0311366918070793,2]
["BP","GO:0071731","response to nitric oxide",0.0311366918070793,2]
["BP","GO:0002573","myeloid leukocyte differentiation",0.031283790341902,7]
["BP","GO:0003014","renal system process",0.0320368398414956,5]
["BP","GO:0010811","positive regulation of cell-substrate adhesion",0.0330329315942239,5]
["BP","GO:1903727","positive regulation of phospholipid metabolic process",0.0333050182324179,3]
["BP","GO:0006525","arginine metabolic process",0.0342671631435184,2]
["BP","GO:0007130","synaptonemal complex assembly",0.0342671631435184,2]
["BP","GO:0033630","positive regulation of cell adhesion mediated by integrin",0.0342671631435184,2]
["BP","GO:0050802","circadian sleep/wake cycle, sleep",0.0342671631435184,2]
["BP","GO:0002704","negative regulation of leukocyte mediated immunity",0.0351035616034307,3]
["BP","GO:0010712","regulation of collagen metabolic process",0.0351035616034307,3]
["BP","GO:0071715","icosanoid transport",0.0351035616034307,3]
["BP","GO:1901571","fatty acid derivative transport",0.0351035616034307,3]
["BP","GO:0051209","release of sequestered calcium ion into cytosol",0.0361361974449621,5]
["BP","GO:0001779","natural killer cell differentiation",0.0375143369671999,2]
["BP","GO:0002438","acute inflammatory response to antigenic stimulus",0.0375143369671999,2]
["BP","GO:0017000","antibiotic biosynthetic process",0.0375143369671999,2]
["BP","GO:0036150","phosphatidylserine acyl-chain remodeling",0.0375143369671999,2]
["BP","GO:0042403","thyroid hormone metabolic process",0.0375143369671999,2]
["BP","GO:0042749","regulation of circadian sleep/wake cycle",0.0375143369671999,2]
["BP","GO:0030101","natural killer cell activation",0.037816094141224,4]
["BP","GO:0051283","negative regulation of sequestering of calcium ion",0.0383015710970838,5]
["BP","GO:0006874","cellular calcium ion homeostasis",0.0385704579790327,12]
["BP","GO:0001954","positive regulation of cell-matrix adhesion",0.0388481156126094,3]
["BP","GO:0002690","positive regulation of leukocyte chemotaxis",0.0391986451265256,4]
["BP","GO:0002687","positive regulation of leukocyte migration",0.0405447407565987,5]
["BP","GO:0051282","regulation of sequestering of calcium ion",0.0405447407565987,5]
["BP","GO:0050829","defense response to Gram-negative bacterium",0.0406097678685499,4]
["BP","GO:0032469","endoplasmic reticulum calcium ion homeostasis",0.040874140657783,2]
["BP","GO:0035584","calcium-mediated signaling using intracellular calcium source",0.040874140657783,2]
["BP","GO:0045624","positive regulation of T-helper cell differentiation",0.040874140657783,2]
["BP","GO:0006968","cellular defense response",0.0427873842114745,3]
["BP","GO:0070228","regulation of lymphocyte apoptotic process",0.0427873842114745,3]
["BP","GO:0051208","sequestering of calcium ion",0.0440562368757295,5]
["BP","GO:0016338","calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules",0.044342595228679,2]
["BP","GO:0022410","circadian sleep/wake cycle process",0.044342595228679,2]
["BP","GO:0036037","CD8-positive, alpha-beta T cell activation",0.044342595228679,2]
["BP","GO:0070193","synaptonemal complex organization",0.044342595228679,2]
["BP","GO:1903429","regulation of cell maturation",0.044342595228679,2]
["BP","GO:0032655","regulation of interleukin-12 production",0.0448292299613837,3]
["BP","GO:0055074","calcium ion homeostasis",0.0459962494497568,12]
["BP","GO:0002705","positive regulation of leukocyte mediated immunity",0.046495526246662,5]
["BP","GO:0043113","receptor clustering",0.0469187411089826,3]
["BP","GO:0043551","regulation of phosphatidylinositol 3-kinase activity",0.0469187411089826,3]
["BP","GO:0050857","positive regulation of antigen receptor-mediated signaling pathway",0.0479158134724737,2]
["BP","GO:1901071","glucosamine-containing compound metabolic process",0.0479158134724737,2]
["BP","GO:0098742","cell-cell adhesion via plasma-membrane adhesion molecules",0.0488999752809854,8]
["BP","GO:0050921","positive regulation of chemotaxis",0.0490137264522907,5]
["BP","GO:0032615","interleukin-12 production",0.0490555344102213,3]
["CC","GO:0019814","immunoglobulin complex",{"v":3.2352924759025e-166,"d":"3.24E-166"},107]
["CC","GO:0042571","immunoglobulin complex, circulating",{"v":2.95777012582395e-79,"d":"2.96E-79"},51]
["CC","GO:0009897","external side of plasma membrane",{"v":1.55291995316763e-59,"d":"1.55E-59"},72]
["CC","GO:0072562","blood microparticle",{"v":1.07101368467203e-23,"d":"1.07E-23"},28]
["CC","GO:0042101","T cell receptor complex",{"v":2.68026048295867e-07,"d":"2.68E-07"},12]
["CC","GO:0098802","plasma membrane receptor complex",{"v":1.19249511231146e-06,"d":"1.19E-06"},17]
["CC","GO:0001772","immunological synapse",0.00163963639097656,4]
["CC","GO:0005882","intermediate filament",0.00361336677601048,9]
["CC","GO:0045111","intermediate filament cytoskeleton",0.00993971086628638,9]
["CC","GO:0045095","keratin filament",0.0114459337847991,5]
["CC","GO:0035580","specific granule lumen",0.01165543684964,4]
["CC","GO:0042599","lamellar body",0.023747269987379,2]
["CC","GO:0031225","anchored component of membrane",0.0347322809619776,6]
["CC","GO:0045121","membrane raft",0.0366304282192229,9]
["CC","GO:0098857","membrane microdomain",0.0372564842941083,9]
["CC","GO:0046930","pore complex",0.0417916136044752,2]
["CC","GO:1904724","tertiary granule lumen",0.0432786319198782,3]
["CC","GO:0098589","membrane region",0.0453464584796977,9]
["MF","GO:0003823","antigen binding",{"v":6.57385504624861e-109,"d":"6.57E-109"},79]
["MF","GO:0034987","immunoglobulin receptor binding",{"v":5.16663479542667e-77,"d":"5.17E-77"},50]
["MF","GO:0004896","cytokine receptor activity",{"v":5.06036908878839e-06,"d":"5.06E-06"},9]
["MF","GO:0016493","C-C chemokine receptor activity",0.000216499192353468,4]
["MF","GO:0019957","C-C chemokine binding",0.000257117798232517,4]
["MF","GO:0001637","G protein-coupled chemoattractant receptor activity",0.000354322222973807,4]
["MF","GO:0004950","chemokine receptor activity",0.000354322222973807,4]
["MF","GO:0019956","chemokine binding",0.00080095294599609,4]
["MF","GO:0047498","calcium-dependent phospholipase A2 activity",0.00112532206631318,3]
["MF","GO:0019955","cytokine binding",0.0015769744208493,7]
["MF","GO:0016709","oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen",0.00170431981331481,4]
["MF","GO:0004497","monooxygenase activity",0.00201898564574784,6]
["MF","GO:0015026","coreceptor activity",0.00267177013450628,4]
["MF","GO:0102567","phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine)",0.00423417434461649,3]
["MF","GO:0102568","phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine)",0.00423417434461649,3]
["MF","GO:0005044","scavenger receptor activity",0.00457730994984383,4]
["MF","GO:0004623","phospholipase A2 activity",0.00929573702348449,3]
["MF","GO:0005501","retinoid binding",0.0109380392392846,3]
["MF","GO:0019840","isoprenoid binding",0.011817959232795,3]
["MF","GO:0043394","proteoglycan binding",0.011817959232795,3]
["MF","GO:0048018","receptor ligand activity",0.0121145328279585,13]
["MF","GO:0070330","aromatase activity",0.0142677475736359,2]
["MF","GO:0019841","retinol binding",0.0163207399655725,2]
["MF","GO:0030280","structural constituent of epidermis",0.018491513951181,2]
["MF","GO:0043395","heparan sulfate proteoglycan binding",0.018491513951181,2]
["MF","GO:0016705","oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen",0.0192171916658856,6]
["MF","GO:0042834","peptidoglycan binding",0.0207766236335071,2]
["MF","GO:0008083","growth factor activity",0.0214216180250603,6]
["MF","GO:0038024","cargo receptor activity",0.0262459661471168,4]
["MF","GO:0061134","peptidase regulator activity",0.0267397198211115,7]
["MF","GO:0005125","cytokine activity",0.0273201436504342,7]
["MF","GO:0004866","endopeptidase inhibitor activity",0.0290442585233123,6]
["MF","GO:0050661","NADP binding",0.031380567822593,3]
["MF","GO:0070851","growth factor receptor binding",0.03279012244203,5]
["MF","GO:0005539","glycosaminoglycan binding",0.0329332102718253,7]
["MF","GO:0020037","heme binding",0.0336989358464749,5]
["MF","GO:0008236","serine-type peptidase activity",0.0342236360465954,6]
["MF","GO:0030414","peptidase inhibitor activity",0.0342236360465954,6]
["MF","GO:0061135","endopeptidase regulator activity",0.0342236360465954,6]
["MF","GO:0004867","serine-type endopeptidase inhibitor activity",0.0361061635054884,4]
["MF","GO:0030159","receptor signaling complex scaffold activity",0.0367040090896738,2]
["MF","GO:0017171","serine hydrolase activity",0.0374352221541139,6]
["MF","GO:0019865","immunoglobulin binding",0.0396986984965145,2]
["MF","GO:0023023","MHC protein complex binding",0.0427825701618968,2]
["MF","GO:0046906","tetrapyrrole binding",0.0436495499302068,5]
["MF","GO:0005112","Notch binding",0.0459527641743335,2]
["MF","GO:0004620","phospholipase activity",0.0464397650510091,4]
["MF","GO:0031210","phosphatidylcholine binding",0.0492064800884413,2]
["MF","GO:0050997","quaternary ammonium group binding",0.0492064800884413,2]

{"sheet":"Supplementary table 2","index":1,"n_rows":28,"n_cols":4,"rows_kept":28,"flags":["formulas_cached_only"]}
["ID","Description","pvalue","Count"]
["hsa05340","Primary immunodeficiency",{"v":3.15554856533318e-10,"d":"3.16E-10"},9]
["hsa04640","Hematopoietic cell lineage",{"v":1.15770062633292e-09,"d":"1.16E-09"},12]
["hsa04514","Cell adhesion molecules",{"v":1.3291218695584e-09,"d":"1.33E-09"},14]
["hsa04060","Cytokine-cytokine receptor interaction",{"v":3.59494905920163e-08,"d":"3.59E-08"},17]
["hsa04660","T cell receptor signaling pathway",{"v":2.84268556996909e-06,"d":"2.84E-06"},9]
["hsa04659","Th17 cell differentiation",{"v":3.27974930849834e-05,"d":"3.28E-05"},8]
["hsa04061","Viral protein interaction with cytokine and cytokine receptor",0.000149231789963778,7]
["hsa04658","Th1 and Th2 cell differentiation",0.000660031538514737,6]
["hsa05144","Malaria",0.00259114734930951,4]
["hsa04630","JAK-STAT signaling pathway",0.00265775462097134,7]
["hsa00592","alpha-Linolenic acid metabolism",0.00288106172729391,3]
["hsa05235","PD-L1 expression and PD-1 checkpoint pathway in cancer",0.00362145104448674,5]
["hsa05166","Human T-cell leukemia virus 1 infection",0.00409344617636734,8]
["hsa00591","Linoleic acid metabolism",0.0044266734046041,3]
["hsa05150","Staphylococcus aureus infection",0.00500588990528228,5]
["hsa00590","Arachidonic acid metabolism",0.00533061466888515,4]
["hsa05162","Measles",0.00538564107298152,6]
["hsa05146","Amoebiasis",0.0064616848005369,5]
["hsa04064","NF-kappa B signaling pathway",0.00700681342716186,5]
["hsa04650","Natural killer cell mediated cytotoxicity",0.0177886244019104,5]
["hsa00565","Ether lipid metabolism",0.0189044187038495,3]
["hsa04915","Estrogen signaling pathway",0.0217614949690854,5]
["hsa04062","Chemokine signaling pathway",0.0237331197476202,6]
["hsa00220","Arginine biosynthesis",0.0264015899313051,2]
["hsa05142","Chagas disease",0.0303750474805107,4]
["hsa05145","Toxoplasmosis",0.0407241959426074,4]
["hsa04670","Leukocyte transendothelial migration",0.0430071228372657,4]