{"text_format":"3","workbook":"xls","n_sheets":3,"sheets":["Supplement Table 1","Supplementary Table 2","Supplementary Table 3"],"not_rendered":{"external_links":1},"read":"whole","date_system":"1900","formulas":"cached_only"}

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["Supplement Table 1. The instrumental variables utilized in the Mendelian Randomization analysis."]
["SNP","chr","effect_allele","other_allele","exposure","outcome","P-value"]
["rs10043984",5,"T","C","Bipolar disorder","hyperthyroidism",{"v":3.71e-08,"d":"3.71E-08"}]
["rs10255167",7,"A","G","Bipolar disorder","hyperthyroidism",{"v":1.6e-08,"d":"1.60E-08"}]
["rs10737496",1,"T","C","Bipolar disorder","hyperthyroidism",{"v":7.17e-09,"d":"7.17E-09"}]
["rs10866641",5,"C","T","Bipolar disorder","hyperthyroidism",{"v":2.79e-11,"d":"2.79E-11"}]
["rs112481526",4,"G","A","Bipolar disorder","hyperthyroidism",{"v":1.86e-09,"d":"1.86E-09"}]
["rs113779084",7,"A","G","Bipolar disorder","hyperthyroidism",{"v":1.42e-13,"d":"1.42E-13"}]
["rs11764361",7,"G","A","Bipolar disorder","hyperthyroidism",{"v":3.47e-09,"d":"3.47E-09"}]
["rs12575685",11,"A","G","Bipolar disorder","hyperthyroidism",{"v":1.24e-10,"d":"1.24E-10"}]
["rs12668848",7,"A","G","Bipolar disorder","hyperthyroidism",{"v":1.9e-09,"d":"1.90E-09"}]
["rs13044225",20,"G","A","Bipolar disorder","hyperthyroidism",{"v":8.5e-09,"d":"8.50E-09"}]
["rs1487445",6,"T","C","Bipolar disorder","hyperthyroidism",{"v":1.48e-15,"d":"1.48E-15"}]
["rs2126180",1,"A","G","Bipolar disorder","hyperthyroidism",{"v":1.62e-09,"d":"1.62E-09"}]
["rs2273738",10,"T","C","Bipolar disorder","hyperthyroidism",{"v":1.63e-11,"d":"1.63E-11"}]
["rs228768",17,"T","G","Bipolar disorder","hyperthyroidism",{"v":2.83e-10,"d":"2.83E-10"}]
["rs2336147",3,"C","T","Bipolar disorder","hyperthyroidism",{"v":3.61e-13,"d":"3.61E-13"}]
["rs237460",20,"T","C","Bipolar disorder","hyperthyroidism",{"v":4.25e-09,"d":"4.25E-09"}]
["rs2693698",14,"G","A","Bipolar disorder","hyperthyroidism",{"v":1.96e-08,"d":"1.96E-08"}]
["rs28455634",16,"A","G","Bipolar disorder","hyperthyroidism",{"v":2.63e-10,"d":"2.63E-10"}]
["rs28565152",5,"A","G","Bipolar disorder","hyperthyroidism",{"v":1.96e-09,"d":"1.96E-09"}]
["rs35306827",13,"A","G","Bipolar disorder","hyperthyroidism",{"v":3.56e-09,"d":"3.56E-09"}]
["rs35958438",15,"A","G","Bipolar disorder","hyperthyroidism",{"v":3.83e-08,"d":"3.83E-08"}]
["rs41315395",6,"A","C","Bipolar disorder","hyperthyroidism",{"v":1.48e-08,"d":"1.48E-08"}]
["rs4447398",15,"C","A","Bipolar disorder","hyperthyroidism",{"v":2.61e-09,"d":"2.61E-09"}]
["rs4619651",2,"A","G","Bipolar disorder","hyperthyroidism",{"v":4.78e-11,"d":"4.78E-11"}]
["rs4790841",17,"T","C","Bipolar disorder","hyperthyroidism",{"v":3.14e-08,"d":"3.14E-08"}]
["rs5758064",22,"C","T","Bipolar disorder","hyperthyroidism",{"v":2.01e-08,"d":"2.01E-08"}]
["rs6104027",20,"G","A","Bipolar disorder","hyperthyroidism",{"v":1.93e-10,"d":"1.93E-10"}]
["rs61554907",17,"T","G","Bipolar disorder","hyperthyroidism",{"v":1.64e-08,"d":"1.64E-08"}]
["rs62581014",9,"T","C","Bipolar disorder","hyperthyroidism",{"v":2.77e-08,"d":"2.77E-08"}]
["rs6806239",3,"G","T","Bipolar disorder","hyperthyroidism",{"v":2.64e-08,"d":"2.64E-08"}]
["rs6887473",5,"A","G","Bipolar disorder","hyperthyroidism",{"v":8.81e-09,"d":"8.81E-09"}]
["rs6946056",7,"C","A","Bipolar disorder","hyperthyroidism",{"v":3.66e-08,"d":"3.66E-08"}]
["rs6954854",7,"A","G","Bipolar disorder","hyperthyroidism",{"v":5.94e-10,"d":"5.94E-10"}]
["rs696366",3,"A","C","Bipolar disorder","hyperthyroidism",{"v":4.46e-08,"d":"4.46E-08"}]
["rs6992333",8,"G","A","Bipolar disorder","hyperthyroidism",{"v":1.62e-09,"d":"1.62E-09"}]
["rs7108878",11,"G","T","Bipolar disorder","hyperthyroidism",{"v":3.61e-08,"d":"3.61E-08"}]
["rs7201930",16,"C","T","Bipolar disorder","hyperthyroidism",{"v":1.89e-08,"d":"1.89E-08"}]
["rs748455",15,"C","T","Bipolar disorder","hyperthyroidism",{"v":5.01e-11,"d":"5.01E-11"}]
["rs7707252",5,"G","A","Bipolar disorder","hyperthyroidism",{"v":3.64e-08,"d":"3.64E-08"}]
["rs10043984",5,"T","C","Bipolar disorder","hypothyroidism",{"v":3.71e-08,"d":"3.71E-08"}]
["rs10255167",7,"A","G","Bipolar disorder","hypothyroidism",{"v":1.6e-08,"d":"1.60E-08"}]
["rs10737496",1,"T","C","Bipolar disorder","hypothyroidism",{"v":7.17e-09,"d":"7.17E-09"}]
["rs10866641",5,"C","T","Bipolar disorder","hypothyroidism",{"v":2.79e-11,"d":"2.79E-11"}]
["rs10994415",10,"C","T","Bipolar disorder","hypothyroidism",{"v":1.14e-11,"d":"1.14E-11"}]
["rs112481526",4,"G","A","Bipolar disorder","hypothyroidism",{"v":1.86e-09,"d":"1.86E-09"}]
["rs113779084",7,"A","G","Bipolar disorder","hypothyroidism",{"v":1.42e-13,"d":"1.42E-13"}]
["rs11764361",7,"G","A","Bipolar disorder","hypothyroidism",{"v":3.47e-09,"d":"3.47E-09"}]
["rs12575685",11,"A","G","Bipolar disorder","hypothyroidism",{"v":1.24e-10,"d":"1.24E-10"}]
["rs12668848",7,"A","G","Bipolar disorder","hypothyroidism",{"v":1.9e-09,"d":"1.90E-09"}]
["rs13044225",20,"G","A","Bipolar disorder","hypothyroidism",{"v":8.5e-09,"d":"8.50E-09"}]
["rs1487445",6,"T","C","Bipolar disorder","hypothyroidism",{"v":1.48e-15,"d":"1.48E-15"}]
["rs17183814",2,"A","G","Bipolar disorder","hypothyroidism",{"v":2.68e-08,"d":"2.68E-08"}]
["rs2126180",1,"A","G","Bipolar disorder","hypothyroidism",{"v":1.62e-09,"d":"1.62E-09"}]
["rs2273738",10,"T","C","Bipolar disorder","hypothyroidism",{"v":1.63e-11,"d":"1.63E-11"}]
["rs228768",17,"T","G","Bipolar disorder","hypothyroidism",{"v":2.83e-10,"d":"2.83E-10"}]
["rs2336147",3,"C","T","Bipolar disorder","hypothyroidism",{"v":3.61e-13,"d":"3.61E-13"}]
["rs237460",20,"T","C","Bipolar disorder","hypothyroidism",{"v":4.25e-09,"d":"4.25E-09"}]
["rs28455634",16,"A","G","Bipolar disorder","hypothyroidism",{"v":2.63e-10,"d":"2.63E-10"}]
["rs28565152",5,"A","G","Bipolar disorder","hypothyroidism",{"v":1.96e-09,"d":"1.96E-09"}]
["rs2953928",8,"A","G","Bipolar disorder","hypothyroidism",{"v":6.25e-09,"d":"6.25E-09"}]
["rs35306827",13,"A","G","Bipolar disorder","hypothyroidism",{"v":3.56e-09,"d":"3.56E-09"}]
["rs35958438",15,"A","G","Bipolar disorder","hypothyroidism",{"v":3.83e-08,"d":"3.83E-08"}]
["rs41315395",6,"A","C","Bipolar disorder","hypothyroidism",{"v":1.48e-08,"d":"1.48E-08"}]
["rs4447398",15,"C","A","Bipolar disorder","hypothyroidism",{"v":2.61e-09,"d":"2.61E-09"}]
["rs4619651",2,"A","G","Bipolar disorder","hypothyroidism",{"v":4.78e-11,"d":"4.78E-11"}]
["rs4790841",17,"T","C","Bipolar disorder","hypothyroidism",{"v":3.14e-08,"d":"3.14E-08"}]
["rs5758064",22,"C","T","Bipolar disorder","hypothyroidism",{"v":2.01e-08,"d":"2.01E-08"}]
["rs6104027",20,"G","A","Bipolar disorder","hypothyroidism",{"v":1.93e-10,"d":"1.93E-10"}]
["rs61554907",17,"T","G","Bipolar disorder","hypothyroidism",{"v":1.64e-08,"d":"1.64E-08"}]
["rs62581014",9,"T","C","Bipolar disorder","hypothyroidism",{"v":2.77e-08,"d":"2.77E-08"}]
["rs6806239",3,"G","T","Bipolar disorder","hypothyroidism",{"v":2.64e-08,"d":"2.64E-08"}]
["rs6887473",5,"A","G","Bipolar disorder","hypothyroidism",{"v":8.81e-09,"d":"8.81E-09"}]
["rs6946056",7,"C","A","Bipolar disorder","hypothyroidism",{"v":3.66e-08,"d":"3.66E-08"}]
["rs6954854",7,"A","G","Bipolar disorder","hypothyroidism",{"v":5.94e-10,"d":"5.94E-10"}]
["rs696366",3,"A","C","Bipolar disorder","hypothyroidism",{"v":4.46e-08,"d":"4.46E-08"}]
["rs6992333",8,"G","A","Bipolar disorder","hypothyroidism",{"v":1.62e-09,"d":"1.62E-09"}]
["rs7108878",11,"G","T","Bipolar disorder","hypothyroidism",{"v":3.61e-08,"d":"3.61E-08"}]
["rs7201930",16,"C","T","Bipolar disorder","hypothyroidism",{"v":1.89e-08,"d":"1.89E-08"}]
["rs748455",15,"C","T","Bipolar disorder","hypothyroidism",{"v":5.01e-11,"d":"5.01E-11"}]
["rs7707252",5,"G","A","Bipolar disorder","hypothyroidism",{"v":3.64e-08,"d":"3.64E-08"}]
["rs10087240",8,"T","C","hyperthyroidism","Bipolar disorder",{"v":3.3e-09,"d":"3.30E-09"}]
["rs12741781",1,"G","T","hyperthyroidism","Bipolar disorder",{"v":4.3e-09,"d":"4.30E-09"}]
["rs1559810",3,"A","C","hyperthyroidism","Bipolar disorder",{"v":2.9e-08,"d":"2.90E-08"}]
["rs1794279",6,"T","G","hyperthyroidism","Bipolar disorder",{"v":6.5e-134,"d":"6.50E-134"}]
["rs185774696",6,"T","C","hyperthyroidism","Bipolar disorder",{"v":3.2e-40,"d":"3.20E-40"}]
["rs3087243",2,"A","G","hyperthyroidism","Bipolar disorder",{"v":7.5e-24,"d":"7.50E-24"}]
["rs4409785",11,"C","T","hyperthyroidism","Bipolar disorder",{"v":9.2e-10,"d":"9.20E-10"}]
["rs6679677",1,"A","C","hyperthyroidism","Bipolar disorder",{"v":1.4e-16,"d":"1.40E-16"}]
["rs7090530",10,"A","C","hyperthyroidism","Bipolar disorder",{"v":4.5e-09,"d":"4.50E-09"}]
["rs71542456",6,"G","A","hyperthyroidism","Bipolar disorder",{"v":2.9e-51,"d":"2.90E-51"}]
["rs9368644",6,"T","C","hyperthyroidism","Bipolar disorder",{"v":2.8e-14,"d":"2.80E-14"}]
["rs10036386",5,"T","C","hypothyroidism","Bipolar disorder",{"v":9.7e-13,"d":"9.70E-13"}]
["rs10277273",7,"G","T","hypothyroidism","Bipolar disorder",{"v":3.1e-09,"d":"3.10E-09"}]
["rs1032129",8,"C","A","hypothyroidism","Bipolar disorder",{"v":3.2e-10,"d":"3.20E-10"}]
["rs10424978",19,"A","C","hypothyroidism","Bipolar disorder",{"v":1.6e-22,"d":"1.60E-22"}]
["rs1050976",6,"T","C","hypothyroidism","Bipolar disorder",{"v":2.9e-13,"d":"2.90E-13"}]
["rs10742340",11,"C","T","hypothyroidism","Bipolar disorder",{"v":4.6e-19,"d":"4.60E-19"}]
["rs1079418",6,"G","A","hypothyroidism","Bipolar disorder",{"v":1.2e-09,"d":"1.20E-09"}]
["rs11052877",12,"G","A","hypothyroidism","Bipolar disorder",{"v":5e-31,"d":"5.00E-31"}]
["rs11073337",15,"C","A","hypothyroidism","Bipolar disorder",{"v":6.5e-17,"d":"6.50E-17"}]
["rs11177053",12,"C","T","hypothyroidism","Bipolar disorder",{"v":2.1e-08,"d":"2.10E-08"}]
["rs11258303",10,"A","C","hypothyroidism","Bipolar disorder",{"v":4.2e-13,"d":"4.20E-13"}]
["rs113473633",4,"G","A","hypothyroidism","Bipolar disorder",{"v":1e-11,"d":"1.00E-11"}]
["rs11675342",2,"T","C","hypothyroidism","Bipolar disorder",{"v":2.7e-29,"d":"2.70E-29"}]
["rs11782370",8,"T","C","hypothyroidism","Bipolar disorder",{"v":4.4e-08,"d":"4.40E-08"}]
["rs11901769",2,"T","A","hypothyroidism","Bipolar disorder",{"v":1.6e-08,"d":"1.60E-08"}]
["rs12271161",11,"A","G","hypothyroidism","Bipolar disorder",{"v":1.7e-10,"d":"1.70E-10"}]
["rs12482947",21,"C","T","hypothyroidism","Bipolar disorder",{"v":5.5e-09,"d":"5.50E-09"}]
["rs1257926",14,"A","G","hypothyroidism","Bipolar disorder",{"v":4.8e-10,"d":"4.80E-10"}]
["rs12582330",12,"T","G","hypothyroidism","Bipolar disorder",{"v":1.6e-15,"d":"1.60E-15"}]
["rs12697352",5,"A","G","hypothyroidism","Bipolar disorder",{"v":2.6e-08,"d":"2.60E-08"}]
["rs12981033",19,"G","A","hypothyroidism","Bipolar disorder",{"v":3.8e-11,"d":"3.80E-11"}]
["rs13090803",3,"T","G","hypothyroidism","Bipolar disorder",{"v":7.5e-19,"d":"7.50E-19"}]
["rs13360007",5,"G","A","hypothyroidism","Bipolar disorder",{"v":2.7e-08,"d":"2.70E-08"}]
["rs13398375",2,"C","T","hypothyroidism","Bipolar disorder",{"v":3.5e-09,"d":"3.50E-09"}]
["rs138453996",16,"A","G","hypothyroidism","Bipolar disorder",{"v":3.4e-11,"d":"3.40E-11"}]
["rs150332089",3,"A","C","hypothyroidism","Bipolar disorder",{"v":1.7e-08,"d":"1.70E-08"}]
["rs1534430",2,"T","C","hypothyroidism","Bipolar disorder",{"v":2.2e-17,"d":"2.20E-17"}]
["rs1549142",19,"T","C","hypothyroidism","Bipolar disorder",{"v":2.1e-13,"d":"2.10E-13"}]
["rs1599795",3,"A","T","hypothyroidism","Bipolar disorder",{"v":2.8e-12,"d":"2.80E-12"}]
["rs17020110",1,"C","T","hypothyroidism","Bipolar disorder",{"v":9.2e-21,"d":"9.20E-21"}]
["rs17129794",1,"C","A","hypothyroidism","Bipolar disorder",{"v":1e-08,"d":"1.00E-08"}]
["rs1723022",1,"T","G","hypothyroidism","Bipolar disorder",{"v":3.5e-09,"d":"3.50E-09"}]
["rs1810396",8,"G","A","hypothyroidism","Bipolar disorder",{"v":4.7e-16,"d":"4.70E-16"}]
["rs1872691",16,"A","G","hypothyroidism","Bipolar disorder",{"v":2.1e-10,"d":"2.10E-10"}]
["rs1921309",2,"A","T","hypothyroidism","Bipolar disorder",{"v":2.6e-09,"d":"2.60E-09"}]
["rs1995311",1,"G","T","hypothyroidism","Bipolar disorder",{"v":4e-09,"d":"4.00E-09"}]
["rs2029751",1,"C","A","hypothyroidism","Bipolar disorder",{"v":1.2e-10,"d":"1.20E-10"}]
["rs2111485",2,"G","A","hypothyroidism","Bipolar disorder",{"v":9.2e-17,"d":"9.20E-17"}]
["rs221781",7,"G","A","hypothyroidism","Bipolar disorder",{"v":2.7e-10,"d":"2.70E-10"}]
["rs2234167",1,"A","G","hypothyroidism","Bipolar disorder",{"v":5.9e-11,"d":"5.90E-11"}]
["rs2254911",3,"C","T","hypothyroidism","Bipolar disorder",{"v":8.5e-10,"d":"8.50E-10"}]
["rs2274780",9,"C","T","hypothyroidism","Bipolar disorder",{"v":3.7e-08,"d":"3.70E-08"}]
["rs229540",22,"G","T","hypothyroidism","Bipolar disorder",{"v":1.3e-29,"d":"1.30E-29"}]
["rs2412974",22,"T","C","hypothyroidism","Bipolar disorder",{"v":3.7e-08,"d":"3.70E-08"}]
["rs244672",5,"T","C","hypothyroidism","Bipolar disorder",{"v":2.9e-13,"d":"2.90E-13"}]
["rs2473808",1,"C","T","hypothyroidism","Bipolar disorder",{"v":4.4e-11,"d":"4.40E-11"}]
["rs2523483",6,"G","T","hypothyroidism","Bipolar disorder",{"v":7.7e-14,"d":"7.70E-14"}]
["rs2736191",6,"G","C","hypothyroidism","Bipolar disorder",{"v":1.1e-10,"d":"1.10E-10"}]
["rs28157",5,"T","G","hypothyroidism","Bipolar disorder",{"v":4.7e-12,"d":"4.70E-12"}]
["rs2823272",21,"A","T","hypothyroidism","Bipolar disorder",{"v":4e-12,"d":"4.00E-12"}]
["rs28418426",6,"C","T","hypothyroidism","Bipolar disorder",{"v":5.8e-79,"d":"5.80E-79"}]
["rs28450181",4,"G","A","hypothyroidism","Bipolar disorder",{"v":3.5e-09,"d":"3.50E-09"}]
["rs2921053",8,"C","G","hypothyroidism","Bipolar disorder",{"v":3.1e-25,"d":"3.10E-25"}]
["rs3087243",2,"A","G","hypothyroidism","Bipolar disorder",{"v":1.7e-82,"d":"1.70E-82"}]
["rs3184504",12,"C","T","hypothyroidism","Bipolar disorder",{"v":3e-116,"d":"3.00E-116"}]
["rs34477738",9,"G","A","hypothyroidism","Bipolar disorder",{"v":4.3e-12,"d":"4.30E-12"}]
["rs34678053",14,"A","G","hypothyroidism","Bipolar disorder",{"v":4.1e-14,"d":"4.10E-14"}]
["rs35074907",19,"A","G","hypothyroidism","Bipolar disorder",{"v":1e-08,"d":"1.00E-08"}]
["rs3775291",4,"T","C","hypothyroidism","Bipolar disorder",{"v":9.2e-17,"d":"9.20E-17"}]
["rs3784099",14,"A","G","hypothyroidism","Bipolar disorder",{"v":5.9e-11,"d":"5.90E-11"}]
["rs3807307",7,"C","T","hypothyroidism","Bipolar disorder",{"v":3e-09,"d":"3.00E-09"}]
["rs3850765",10,"C","T","hypothyroidism","Bipolar disorder",{"v":3.3e-12,"d":"3.30E-12"}]
["rs4409785",11,"C","T","hypothyroidism","Bipolar disorder",{"v":4.3e-31,"d":"4.30E-31"}]
["rs4444866",4,"T","C","hypothyroidism","Bipolar disorder",{"v":2.9e-11,"d":"2.90E-11"}]
["rs4794063",17,"T","C","hypothyroidism","Bipolar disorder",{"v":3.9e-15,"d":"3.90E-15"}]
["rs479777",11,"C","T","hypothyroidism","Bipolar disorder",{"v":1.6e-10,"d":"1.60E-10"}]
["rs4824117",22,"G","A","hypothyroidism","Bipolar disorder",{"v":6.1e-09,"d":"6.10E-09"}]
["rs4835536",4,"T","G","hypothyroidism","Bipolar disorder",{"v":4.3e-32,"d":"4.30E-32"}]
["rs56249713",18,"C","T","hypothyroidism","Bipolar disorder",{"v":8.2e-11,"d":"8.20E-11"}]
["rs56400413",7,"A","T","hypothyroidism","Bipolar disorder",{"v":2.3e-08,"d":"2.30E-08"}]
["rs57938373",3,"T","C","hypothyroidism","Bipolar disorder",{"v":4e-11,"d":"4.00E-11"}]
["rs5865",2,"T","C","hypothyroidism","Bipolar disorder",{"v":4.8e-11,"d":"4.80E-11"}]
["rs60600003",7,"G","T","hypothyroidism","Bipolar disorder",{"v":2e-09,"d":"2.00E-09"}]
["rs6111715",20,"C","G","hypothyroidism","Bipolar disorder",{"v":4.8e-11,"d":"4.80E-11"}]
["rs61759532",17,"T","C","hypothyroidism","Bipolar disorder",{"v":2.7e-14,"d":"2.70E-14"}]
["rs61776678",1,"A","G","hypothyroidism","Bipolar disorder",{"v":1.6e-10,"d":"1.60E-10"}]
["rs61778693",1,"T","G","hypothyroidism","Bipolar disorder",{"v":4.2e-09,"d":"4.20E-09"}]
["rs6452444",5,"C","T","hypothyroidism","Bipolar disorder",{"v":1.1e-08,"d":"1.10E-08"}]
["rs6505765",18,"G","C","hypothyroidism","Bipolar disorder",{"v":8e-13,"d":"8.00E-13"}]
["rs6584277",10,"G","A","hypothyroidism","Bipolar disorder",{"v":6.2e-11,"d":"6.20E-11"}]
["rs66749983",13,"T","A","hypothyroidism","Bipolar disorder",{"v":1e-14,"d":"1.00E-14"}]
["rs6679677",1,"A","C","hypothyroidism","Bipolar disorder",{"v":5.11e-167,"d":"5.11E-167"}]
["rs6739788",2,"T","A","hypothyroidism","Bipolar disorder",{"v":9.9e-09,"d":"9.90E-09"}]
["rs6798068",3,"A","G","hypothyroidism","Bipolar disorder",{"v":3.2e-09,"d":"3.20E-09"}]
["rs6833591",4,"G","A","hypothyroidism","Bipolar disorder",{"v":7.3e-10,"d":"7.30E-10"}]
["rs6992869",8,"C","T","hypothyroidism","Bipolar disorder",{"v":2.5e-10,"d":"2.50E-10"}]
["rs7005834",8,"T","C","hypothyroidism","Bipolar disorder",{"v":1.2e-11,"d":"1.20E-11"}]
["rs7090530",10,"A","C","hypothyroidism","Bipolar disorder",{"v":3.7e-20,"d":"3.70E-20"}]
["rs71508903",10,"T","C","hypothyroidism","Bipolar disorder",{"v":1e-31,"d":"1.00E-31"}]
["rs731151",17,"A","G","hypothyroidism","Bipolar disorder",{"v":2.4e-12,"d":"2.40E-12"}]
["rs7441808",4,"G","A","hypothyroidism","Bipolar disorder",{"v":4.8e-16,"d":"4.80E-16"}]
["rs7582694",2,"G","C","hypothyroidism","Bipolar disorder",{"v":1.6e-37,"d":"1.60E-37"}]
["rs7583027",2,"C","A","hypothyroidism","Bipolar disorder",{"v":3.3e-10,"d":"3.30E-10"}]
["rs761357",6,"T","A","hypothyroidism","Bipolar disorder",{"v":3.4e-10,"d":"3.40E-10"}]
["rs7649344",3,"C","T","hypothyroidism","Bipolar disorder",{"v":4e-09,"d":"4.00E-09"}]
["rs76518703",6,"G","A","hypothyroidism","Bipolar disorder",{"v":5.6e-21,"d":"5.60E-21"}]
["rs7705526",5,"A","C","hypothyroidism","Bipolar disorder",{"v":1.4e-09,"d":"1.40E-09"}]
["rs772920",12,"G","C","hypothyroidism","Bipolar disorder",{"v":1.9e-14,"d":"1.90E-14"}]
["rs7754251",6,"C","G","hypothyroidism","Bipolar disorder",{"v":4.2e-38,"d":"4.20E-38"}]
["rs7768019",6,"G","C","hypothyroidism","Bipolar disorder",{"v":1.2e-53,"d":"1.20E-53"}]
["rs7850258",9,"G","A","hypothyroidism","Bipolar disorder",{"v":1.9e-98,"d":"1.90E-98"}]
["rs7936397",11,"A","G","hypothyroidism","Bipolar disorder",{"v":3.6e-09,"d":"3.60E-09"}]
["rs79490353",13,"C","T","hypothyroidism","Bipolar disorder",{"v":2.3e-13,"d":"2.30E-13"}]
["rs8054578",16,"G","A","hypothyroidism","Bipolar disorder",{"v":1.2e-10,"d":"1.20E-10"}]
["rs8093850",18,"G","A","hypothyroidism","Bipolar disorder",{"v":4.9e-09,"d":"4.90E-09"}]
["rs897586",8,"A","G","hypothyroidism","Bipolar disorder",{"v":5.1e-14,"d":"5.10E-14"}]
["rs9272426",6,"G","A","hypothyroidism","Bipolar disorder",{"v":2.6e-168,"d":"2.60E-168"}]
["rs9277569",6,"T","C","hypothyroidism","Bipolar disorder",{"v":7.6e-32,"d":"7.60E-32"}]
["rs9291444",4,"T","C","hypothyroidism","Bipolar disorder",{"v":3.3e-17,"d":"3.30E-17"}]
["rs9347170",6,"T","C","hypothyroidism","Bipolar disorder",{"v":4.3e-33,"d":"4.30E-33"}]
["rs9497965",6,"T","C","hypothyroidism","Bipolar disorder",{"v":5.8e-18,"d":"5.80E-18"}]
["rs9511151",13,"A","G","hypothyroidism","Bipolar disorder",{"v":1.1e-40,"d":"1.10E-40"}]
["rs9557168",13,"A","G","hypothyroidism","Bipolar disorder",{"v":2.8e-08,"d":"2.80E-08"}]
["rs9697210",9,"A","G","hypothyroidism","Bipolar disorder",{"v":5e-09,"d":"5.00E-09"}]
["rs970987",9,"A","C","hypothyroidism","Bipolar disorder",{"v":1e-16,"d":"1.00E-16"}]

{"sheet":"Supplementary Table 2","index":1,"n_rows":11,"n_cols":10,"rows_kept":11,"flags":["formulas_cached_only"]}
["Supplementary Table 2. The effects of Genetic predicted bipolar disorder on thyroid dysfunction in the MR analysis."]
["Exposure","Outcome","NSNP","Methods","OR (95%CI)","P-values","Egger_intercept","P-Egger_intercept","Q","P-Q"]
["Bipolar disorder","Hyperthyroidism",39,"MR Egger","0.994 (0.986-1.003)",0.179,0.0003,0.25]
[{"$nulls":3},"Weighted median","0.999 (0.997-1.000)",0.056]
[{"$nulls":3},"IVW","0.999 (0.998-1.000)",0.105]
[{"$nulls":3},"IVW (MRE)","0.999 (0.998-1.000)",0.105,null,null,51.554,0.104]
["Bipolar disorder","Hypothyroidism",41,"MR Egger","0.990 (0.974-1.006)",0.234,0.0004,0.476]
[{"$nulls":3},"Weighted median","0.995 (0.992-0.999)",0.009]
[{"$nulls":3},"IVW","0.996 (0.993-0.999)",0.003]
[{"$nulls":3},"IVW (MRE)","0.996 (0.993-0.999)",0.003,null,null,111.77,"4.97*10-8"]
["SNP, Single nucleotide polymorphisms; IVW, inverse-variance weighted; MRE, multiplicative random effects; OR, odds ratio; CI, confidence interval."]

{"sheet":"Supplementary Table 3","index":2,"n_rows":11,"n_cols":10,"rows_kept":11,"flags":["formulas_cached_only"]}
["Supplementary Table 3. The effects of Genetic predicted thyroid dysfunction on bipolar disorder in the MR analysis."]
["Exposure","Outcome","nSNP","Methods","OR (95%CI)","P-values","Egger_intercept","P-Egger_intercept","Q","P-Q"]
["Hyperthyroidism","Bipolar disorder",11,"MR Egger","3.33*10-5 (1.06*10-8 -0.104)",0.033,0.0039,0.182]
[{"$nulls":3},"Weighted median","2.16*10-5 (3.25*10-7-0.001)","5.30-10-7"]
[{"$nulls":3},"IVW","1.68*10-5 (1.72*10-7-0.002)","2.52*10-6",null,null,20.318,0.026]
[{"$nulls":3},"IVW (MRE)","1.68*10-5 (1.72*10-7-0.002)","2.52*10-6",null,null,20.318,0.026]
["Hypothyroidism","Bipolar disorder",99,"MR Egger","0.370 (0.107-1.272)",0.118,-0.0019,0.84]
[{"$nulls":3},"Weighted median","0.714 (0.318-1.604)",0.415]
[{"$nulls":3},"IVW","0.782 (0.439-1.394)",0.405,null,null,171.44,"1.16*10-5"]
[{"$nulls":3},"IVW (MRE)","0.782 (0.439-1.394)",0.405,null,null,171.44,"1.16*10-5"]
["SNP, Single nucleotide polymorphisms; IVW, inverse-variance weighted; MRE, multiplicative random effects; OR, odds ratio; CI, confidence interval."]