##Databases: Gene Ontology (GO) pathway and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway															
##GO_id: the id of GO term															
															
															
gene_id	FoldChange	log2FoldChange	p-value	Regulation	Expression_Ma1	Expression_Ma2	Expression_Ma3	Expression_Ea1	Expression_Ea2	Expression_Ea3	description	GO_id	GO_term	KEGG pathway	KEGG pathway description
4833420G17Rik	1.206133123	0.270389149	0.02614563	Up	7.272600335	7.263504708	7.856754093	8.403098312	9.881944739	8.933535929	RIKEN cDNA 4833420G17 gene				
Adipor2	1.325077432	0.406076668	1.51E-07	Up	14.19515922	13.48116199	14.62982234	17.69148257	19.03848356	19.71429999	adiponectin receptor 2	"GO:0001934,GO:0005515,GO:0005886,GO:0006629,GO:0006631,GO:0009755,GO:0010629,GO:0016020,GO:0016021,GO:0019395,GO:0030308,GO:0031226,GO:0033211,GO:0038023,GO:0042593,GO:0042802,GO:0046326,GO:0046872,GO:0055100,GO:0061042,GO:0061871,GO:0097003,GO:0120162"	positive regulation of protein phosphorylation|protein binding|plasma membrane|lipid metabolic process|fatty acid metabolic process|hormone-mediated signaling pathway|negative regulation of gene expression|membrane|integral component of membrane|fatty acid oxidation|negative regulation of cell growth|intrinsic component of plasma membrane|adiponectin-activated signaling pathway|signaling receptor activity|glucose homeostasis|identical protein binding|positive regulation of glucose import|metal ion binding|adiponectin binding|vascular wound healing|negative regulation of hepatic stellate cell migration|adipokinetic hormone receptor activity|positive regulation of cold-induced thermogenesis	"mmu04152,mmu04211,mmu04920,mmu04932"	AMPK signaling pathway|Longevity regulating pathway|Adipocytokine signaling pathway|Non-alcoholic fatty liver disease
Alas2	1.552871443	0.634938399	0.024626867	Up	1.720429888	1.591816133	2.892279231	3.622979858	2.908024224	2.913856112	"aminolevulinic acid synthase 2, erythroid"	"GO:0001666,GO:0003824,GO:0003870,GO:0005739,GO:0005743,GO:0005759,GO:0006778,GO:0006783,GO:0006879,GO:0009058,GO:0016740,GO:0016746,GO:0030170,GO:0030218,GO:0033014,GO:0042541,GO:0048821,GO:0120225"	response to hypoxia|catalytic activity|5-aminolevulinate synthase activity|mitochondrion|mitochondrial inner membrane|mitochondrial matrix|porphyrin-containing compound metabolic process|heme biosynthetic process|cellular iron ion homeostasis|biosynthetic process|transferase activity|acyltransferase activity|pyridoxal phosphate binding|erythrocyte differentiation|tetrapyrrole biosynthetic process|hemoglobin biosynthetic process|erythrocyte development|coenzyme A binding	"mmu00260,mmu00860"	"Glycine, serine and threonine metabolism|Porphyrin and chlorophyll metabolism"
Ankrd10	1.229480336	0.29804866	0.013922661	Up	2.980276409	2.977222558	3.844291023	3.451566185	4.496084483	4.168053503	ankyrin repeat domain 10				
Ano2	1.548575055	0.630941308	0.007139795	Up	1.309241352	1.018101243	1.124854887	1.851936685	1.973753763	1.555598316	anoctamin 2	"GO:0005229,GO:0005254,GO:0005515,GO:0005654,GO:0005886,GO:0006811,GO:0006821,GO:0016020,GO:0016021,GO:0017128,GO:0034707,GO:0042802,GO:0046983,GO:0055085,GO:0097730,GO:1902476"	intracellular calcium activated chloride channel activity|chloride channel activity|protein binding|nucleoplasm|plasma membrane|ion transport|chloride transport|membrane|integral component of membrane|phospholipid scramblase activity|chloride channel complex|identical protein binding|protein dimerization activity|transmembrane transport|non-motile cilium|chloride transmembrane transport	mmu04740	Olfactory transduction
Apln	0.748036553	-0.418819326	6.95E-05	Down	10.37368711	12.72612618	13.99133992	7.679616343	9.20034474	11.13272901	apelin	"GO:0001525,GO:0002026,GO:0005102,GO:0005179,GO:0005576,GO:0005615,GO:0007165,GO:0007186,GO:0007275,GO:0007369,GO:0007631,GO:0008284,GO:0010629,GO:0031652,GO:0031704,GO:0040037,GO:0042327,GO:0042756,GO:0042802,GO:0043576,GO:0045776,GO:0045823,GO:0045906,GO:0048471,GO:0050878,GO:0051461,GO:0051466,GO:0060183,GO:0060976,GO:1902895,GO:1904022,GO:1904706,GO:1905564"	angiogenesis|regulation of the force of heart contraction|signaling receptor binding|hormone activity|extracellular region|extracellular space|signal transduction|G protein-coupled receptor signaling pathway|multicellular organism development|gastrulation|feeding behavior|positive regulation of cell population proliferation|negative regulation of gene expression|positive regulation of heat generation|apelin receptor binding|negative regulation of fibroblast growth factor receptor signaling pathway|positive regulation of phosphorylation|drinking behavior|identical protein binding|regulation of respiratory gaseous exchange|negative regulation of blood pressure|positive regulation of heart contraction|negative regulation of vasoconstriction|perinuclear region of cytoplasm|regulation of body fluid levels|positive regulation of corticotropin secretion|positive regulation of corticotropin-releasing hormone secretion|apelin receptor signaling pathway|coronary vasculature development|positive regulation of pri-miRNA transcription by RNA polymerase II|positive regulation of G protein-coupled receptor internalization|negative regulation of vascular associated smooth muscle cell proliferation|positive regulation of vascular endothelial cell proliferation	"mmu04080,mmu04371"	Neuroactive ligand-receptor interaction|Apelin signaling pathway
Arhgef19	0.810461291	-0.303184812	0.020840296	Down	3.941142463	4.903434027	4.950945803	3.300457455	3.692101008	4.261462992	Rho guanine nucleotide exchange factor (GEF) 19	"GO:0005085,GO:0005096,GO:0032956,GO:0042060,GO:0043547,GO:0090630"	guanyl-nucleotide exchange factor activity|GTPase activator activity|regulation of actin cytoskeleton organization|wound healing|positive regulation of GTPase activity|activation of GTPase activity		
Arl4d	1.292011415	0.369618817	0.008601499	Up	10.50546413	12.87931859	14.91240843	11.2834742	18.36239804	21.11201303	ADP-ribosylation factor-like 4D	"GO:0000166,GO:0005525,GO:0005634,GO:0005737,GO:0005886,GO:0006886,GO:0016020,GO:0016192"	nucleotide binding|GTP binding|nucleus|cytoplasm|plasma membrane|intracellular protein transport|membrane|vesicle-mediated transport		
Arrdc2	1.313129571	0.393009279	0.03198995	Up	3.936166849	4.304490539	3.717899748	4.366282287	5.611489848	5.921268905	arrestin domain containing 2	"GO:0005737,GO:0005886,GO:0015031,GO:0031410"	cytoplasm|plasma membrane|protein transport|cytoplasmic vesicle		
Atp10a	1.353646721	0.436851269	0.009050078	Up	1.575384478	1.569084857	1.62539685	2.114102691	2.13788318	2.24755342	"ATPase, class V, type 10A"	"GO:0000166,GO:0000287,GO:0005524,GO:0005783,GO:0005886,GO:0005887,GO:0006869,GO:0015914,GO:0016020,GO:0016021,GO:0045332,GO:0046872,GO:0140326,GO:0140345,GO:0140351,GO:1903527,GO:1990531"	nucleotide binding|magnesium ion binding|ATP binding|endoplasmic reticulum|plasma membrane|integral component of plasma membrane|lipid transport|phospholipid transport|membrane|integral component of membrane|phospholipid translocation|metal ion binding|ATPase-coupled intramembrane lipid transporter activity|phosphatidylcholine flippase activity|glycosylceramide flippase activity|positive regulation of membrane tubulation|phospholipid-translocating ATPase complex		
B3galnt2	1.375967339	0.460446226	0.021796075	Up	2.797199372	2.759937281	3.003453705	3.305461974	4.247270434	4.37043383	"UDP-GalNAc:betaGlcNAc beta 1,3-galactosaminyltransferase, polypeptide 2"	"GO:0005783,GO:0005794,GO:0006486,GO:0006493,GO:0008376,GO:0016020,GO:0016021,GO:0016740,GO:0016757,GO:0019276"	endoplasmic reticulum|Golgi apparatus|protein glycosylation|protein O-linked glycosylation|acetylgalactosaminyltransferase activity|membrane|integral component of membrane|transferase activity|glycosyltransferase activity|UDP-N-acetylgalactosamine metabolic process	mmu00515	Mannose type O-glycan biosynthesis
Bfsp1	9.492244037	3.246749191	0.005534056	Up	0.236538109	0.144707594	4.68386072	4.368089819	4.19988823	5.064341057	"beaded filament structural protein 1, in lens-CP94"	"GO:0005212,GO:0005515,GO:0005737,GO:0005856,GO:0005882,GO:0005886,GO:0016020,GO:0045109,GO:0048469,GO:0070307"	structural constituent of eye lens|protein binding|cytoplasm|cytoskeleton|intermediate filament|plasma membrane|membrane|intermediate filament organization|cell maturation|lens fiber cell development		
Bfsp2	1.936375697	0.953358893	0.018687626	Up	2.120583226	2.382823943	6.480340381	6.267326921	5.393403653	7.233436184	"beaded filament structural protein 2, phakinin"	"GO:0005198,GO:0005212,GO:0005515,GO:0005737,GO:0005856,GO:0005882,GO:0005886,GO:0007010,GO:0007601,GO:0016020,GO:0045104,GO:0045109,GO:0048469,GO:0050896,GO:0070307"	structural molecule activity|structural constituent of eye lens|protein binding|cytoplasm|cytoskeleton|intermediate filament|plasma membrane|cytoskeleton organization|visual perception|membrane|intermediate filament cytoskeleton organization|intermediate filament organization|cell maturation|response to stimulus|lens fiber cell development		
Bhlhe40	1.249106777	0.320896807	1.01E-05	Up	36.33068148	31.46429842	34.16332743	39.64689578	43.22200099	45.2977437	"basic helix-loop-helix family, member e40"	"GO:0000122,GO:0000978,GO:0000981,GO:0001227,GO:0003677,GO:0005515,GO:0005634,GO:0005654,GO:0005737,GO:0006355,GO:0006357,GO:0007623,GO:0009416,GO:0009952,GO:0016604,GO:0019904,GO:0032922,GO:0042752,GO:0042803,GO:0043153,GO:0043425,GO:0043426,GO:0043433,GO:0045892,GO:0046982,GO:0046983,GO:0048511,GO:0050767,GO:0061629,GO:0070888,GO:1990837"	"negative regulation of transcription by RNA polymerase II|RNA polymerase II cis-regulatory region sequence-specific DNA binding|DNA-binding transcription factor activity, RNA polymerase II-specific|DNA-binding transcription repressor activity, RNA polymerase II-specific|DNA binding|protein binding|nucleus|nucleoplasm|cytoplasm|regulation of transcription, DNA-templated|regulation of transcription by RNA polymerase II|circadian rhythm|response to light stimulus|anterior/posterior pattern specification|nuclear body|protein domain specific binding|circadian regulation of gene expression|regulation of circadian rhythm|protein homodimerization activity|entrainment of circadian clock by photoperiod|bHLH transcription factor binding|MRF binding|negative regulation of DNA-binding transcription factor activity|negative regulation of transcription, DNA-templated|protein heterodimerization activity|protein dimerization activity|rhythmic process|regulation of neurogenesis|RNA polymerase II-specific DNA-binding transcription factor binding|E-box binding|sequence-specific double-stranded DNA binding"	mmu04710	Circadian rhythm
Caprin2	1.723654015	0.785470215	0.002349823	Up	0.897499573	0.973344055	1.897152247	1.853659767	2.342746828	2.043658072	caprin family member 2	"GO:0003723,GO:0005102,GO:0005654,GO:0005737,GO:0005739,GO:0005813,GO:0005829,GO:0005886,GO:0016020,GO:0017148,GO:0030154,GO:0030308,GO:0032092,GO:0033138,GO:0040008,GO:0043235,GO:0045944,GO:0046872,GO:0050775,GO:0061003,GO:0090263"	RNA binding|signaling receptor binding|nucleoplasm|cytoplasm|mitochondrion|centrosome|cytosol|plasma membrane|membrane|negative regulation of translation|cell differentiation|negative regulation of cell growth|positive regulation of protein binding|positive regulation of peptidyl-serine phosphorylation|regulation of growth|receptor complex|positive regulation of transcription by RNA polymerase II|metal ion binding|positive regulation of dendrite morphogenesis|positive regulation of dendritic spine morphogenesis|positive regulation of canonical Wnt signaling pathway		
Ccdc117	1.325226341	0.406238785	0.001862335	Up	5.056239632	5.185548813	5.98197853	6.296957437	6.868852065	8.576367434	coiled-coil domain containing 117				
Ccdc190	0.799332754	-0.323131887	0.032719009	Down	7.339456262	9.322771425	7.797344449	6.525369215	6.771799277	6.302094549	coiled-coil domain containing 190				
Ccl27b	1.888087038	0.916925272	0.026678935	Up	0.294697183	0.398272002	0.491919047	0.429639381	0.918162765	0.972575754	chemokine (C-C motif) ligand 27b	"GO:0031640,GO:0031728,GO:0061844"	killing of cells of other organism|CCR3 chemokine receptor binding|antimicrobial humoral immune response mediated by antimicrobial peptide	"mmu04060,mmu04061,mmu04062"	Cytokine-cytokine receptor interaction|Viral protein interaction with cytokine and cytokine receptor|Chemokine signaling pathway
Ccnl1	1.294478573	0.372371085	0.004005337	Up	2.153955632	2.077987093	2.74119821	2.573020475	3.144409272	3.356377288	cyclin L1	"GO:0000079,GO:0005515,GO:0005634,GO:0005737,GO:0006355,GO:0006357,GO:0006396,GO:0008023,GO:0016538,GO:0016607"	"regulation of cyclin-dependent protein serine/threonine kinase activity|protein binding|nucleus|cytoplasm|regulation of transcription, DNA-templated|regulation of transcription by RNA polymerase II|RNA processing|transcription elongation factor complex|cyclin-dependent protein serine/threonine kinase regulator activity|nuclear speck"		
Cebpd	1.39031019	0.475406796	0.041147729	Up	2.374137881	2.283504467	2.354028535	3.076674225	3.2282477	3.518680792	"CCAAT/enhancer binding protein (C/EBP), delta"	"GO:0000976,GO:0000978,GO:0000981,GO:0001228,GO:0002244,GO:0003677,GO:0003700,GO:0005515,GO:0005634,GO:0005654,GO:0006355,GO:0006357,GO:0042802,GO:0043565,GO:0045444,GO:0045595,GO:0045669,GO:0045892,GO:0045944,GO:0048839,GO:1990837"	"transcription cis-regulatory region binding|RNA polymerase II cis-regulatory region sequence-specific DNA binding|DNA-binding transcription factor activity, RNA polymerase II-specific|DNA-binding transcription activator activity, RNA polymerase II-specific|hematopoietic progenitor cell differentiation|DNA binding|DNA-binding transcription factor activity|protein binding|nucleus|nucleoplasm|regulation of transcription, DNA-templated|regulation of transcription by RNA polymerase II|identical protein binding|sequence-specific DNA binding|fat cell differentiation|regulation of cell differentiation|positive regulation of osteoblast differentiation|negative regulation of transcription, DNA-templated|positive regulation of transcription by RNA polymerase II|inner ear development|sequence-specific double-stranded DNA binding"		
Celsr3	1.218432674	0.285026535	0.001749346	Up	3.620515921	3.681896996	4.16194728	4.08965195	5.001065277	4.996612082	"cadherin, EGF LAG seven-pass G-type receptor 3"	"GO:0001764,GO:0001932,GO:0004888,GO:0004930,GO:0005509,GO:0005886,GO:0007155,GO:0007156,GO:0007165,GO:0007166,GO:0007186,GO:0007275,GO:0007413,GO:0016020,GO:0016021,GO:0032880,GO:0036514,GO:0036515,GO:0060271,GO:0098609,GO:1904938"	neuron migration|regulation of protein phosphorylation|transmembrane signaling receptor activity|G protein-coupled receptor activity|calcium ion binding|plasma membrane|cell adhesion|homophilic cell adhesion via plasma membrane adhesion molecules|signal transduction|cell surface receptor signaling pathway|G protein-coupled receptor signaling pathway|multicellular organism development|axonal fasciculation|membrane|integral component of membrane|regulation of protein localization|dopaminergic neuron axon guidance|serotonergic neuron axon guidance|cilium assembly|cell-cell adhesion|planar cell polarity pathway involved in axon guidance		
Cep164	1.310266742	0.389860543	0.045715103	Up	1.315744051	1.126179335	1.530941155	1.355545562	2.15546521	1.778938344	centrosomal protein 164	"GO:0005515,GO:0005634,GO:0005654,GO:0005737,GO:0005813,GO:0005814,GO:0005856,GO:0005929,GO:0006281,GO:0006974,GO:0007049,GO:0030030,GO:0045177,GO:0051301,GO:0060271,GO:0097539,GO:0097729"	protein binding|nucleus|nucleoplasm|cytoplasm|centrosome|centriole|cytoskeleton|cilium|DNA repair|cellular response to DNA damage stimulus|cell cycle|cell projection organization|apical part of cell|cell division|cilium assembly|ciliary transition fiber|9+2 motile cilium		
Chrng	24.31448121	4.603743905	0.044264543	Up	0	0	0.350088373	0.346533954	0.441029442	0.321176712	"cholinergic receptor, nicotinic, gamma polypeptide"	"GO:0003009,GO:0004888,GO:0005216,GO:0005230,GO:0005515,GO:0005886,GO:0005887,GO:0005892,GO:0006811,GO:0006812,GO:0007165,GO:0007268,GO:0015276,GO:0016020,GO:0016021,GO:0022848,GO:0030054,GO:0030594,GO:0034220,GO:0042391,GO:0043005,GO:0045202,GO:0045211,GO:0050877"	skeletal muscle contraction|transmembrane signaling receptor activity|ion channel activity|extracellular ligand-gated ion channel activity|protein binding|plasma membrane|integral component of plasma membrane|acetylcholine-gated channel complex|ion transport|cation transport|signal transduction|chemical synaptic transmission|ligand-gated ion channel activity|membrane|integral component of membrane|acetylcholine-gated cation-selective channel activity|cell junction|neurotransmitter receptor activity|ion transmembrane transport|regulation of membrane potential|neuron projection|synapse|postsynaptic membrane|nervous system process	mmu04080	Neuroactive ligand-receptor interaction
Ciart	1.956888124	0.968561279	3.17E-10	Up	4.790195864	4.329165169	4.072019595	8.600213942	8.893125353	8.452171625	circadian associated repressor of transcription	"GO:0000976,GO:0000978,GO:0005515,GO:0005634,GO:0032922,GO:0045475,GO:0045892,GO:0048511,GO:0070888"	"transcription cis-regulatory region binding|RNA polymerase II cis-regulatory region sequence-specific DNA binding|protein binding|nucleus|circadian regulation of gene expression|locomotor rhythm|negative regulation of transcription, DNA-templated|rhythmic process|E-box binding"		
Cldn5	0.68423968	-0.547426325	0.006592465	Down	27.23045677	30.7929511	33.92365459	24.91362261	19.07892276	19.5372602	claudin 5	"GO:0005198,GO:0005515,GO:0005886,GO:0005911,GO:0005923,GO:0007043,GO:0007155,GO:0007179,GO:0008284,GO:0010628,GO:0010629,GO:0016020,GO:0016021,GO:0016327,GO:0016328,GO:0016525,GO:0030054,GO:0030336,GO:0030864,GO:0032092,GO:0033270,GO:0035633,GO:0042552,GO:0043116,GO:0043220,GO:0070160,GO:0070830,GO:0098609,GO:0120192,GO:1903142,GO:1903348,GO:1990963"	structural molecule activity|protein binding|plasma membrane|cell-cell junction|bicellular tight junction|cell-cell junction assembly|cell adhesion|transforming growth factor beta receptor signaling pathway|positive regulation of cell population proliferation|positive regulation of gene expression|negative regulation of gene expression|membrane|integral component of membrane|apicolateral plasma membrane|lateral plasma membrane|negative regulation of angiogenesis|cell junction|negative regulation of cell migration|cortical actin cytoskeleton|positive regulation of protein binding|paranode region of axon|maintenance of blood-brain barrier|myelination|negative regulation of vascular permeability|Schmidt-Lanterman incisure|tight junction|bicellular tight junction assembly|cell-cell adhesion|tight junction assembly|positive regulation of establishment of endothelial barrier|positive regulation of bicellular tight junction assembly|establishment of blood-retinal barrier	"mmu04514,mmu04530,mmu04670,mmu05160"	Cell adhesion molecules|Tight junction|Leukocyte transendothelial migration|Hepatitis C
Clk1	1.598338028	0.676572552	0.016868402	Up	15.34985836	15.2801515	18.8542087	16.70710255	32.78996664	33.41731202	CDC-like kinase 1	"GO:0000166,GO:0004672,GO:0004674,GO:0004712,GO:0004713,GO:0005515,GO:0005524,GO:0005634,GO:0005737,GO:0006468,GO:0016301,GO:0016310,GO:0016740,GO:0018105,GO:0018107,GO:0018108,GO:0043484,GO:0046777"	nucleotide binding|protein kinase activity|protein serine/threonine kinase activity|protein serine/threonine/tyrosine kinase activity|protein tyrosine kinase activity|protein binding|ATP binding|nucleus|cytoplasm|protein phosphorylation|kinase activity|phosphorylation|transferase activity|peptidyl-serine phosphorylation|peptidyl-threonine phosphorylation|peptidyl-tyrosine phosphorylation|regulation of RNA splicing|protein autophosphorylation	mmu05134	Legionellosis
Clk4	1.471776788	0.557558886	0.028279464	Up	4.230516202	3.956790852	5.186513202	4.663936879	8.175651685	7.386232445	CDC like kinase 4	"GO:0000166,GO:0004672,GO:0004674,GO:0004712,GO:0004713,GO:0005524,GO:0005634,GO:0006468,GO:0016301,GO:0016310,GO:0016740,GO:0018108,GO:0043484,GO:0046777"	nucleotide binding|protein kinase activity|protein serine/threonine kinase activity|protein serine/threonine/tyrosine kinase activity|protein tyrosine kinase activity|ATP binding|nucleus|protein phosphorylation|kinase activity|phosphorylation|transferase activity|peptidyl-tyrosine phosphorylation|regulation of RNA splicing|protein autophosphorylation	mmu05134	Legionellosis
Col4a5	1.499558054	0.584537376	0.026617832	Up	0.586177934	0.57073562	0.654415279	0.803860464	0.968433601	0.965985949	"collagen, type IV, alpha 5"	"GO:0005201,GO:0005587,GO:0005604,GO:0005615,GO:0007528,GO:0030020,GO:0030198,GO:0031012,GO:0031594,GO:0038063,GO:0062023"	extracellular matrix structural constituent|collagen type IV trimer|basement membrane|extracellular space|neuromuscular junction development|extracellular matrix structural constituent conferring tensile strength|extracellular matrix organization|extracellular matrix|neuromuscular junction|collagen-activated tyrosine kinase receptor signaling pathway|collagen-containing extracellular matrix	"mmu04151,mmu04510,mmu04512,mmu04926,mmu04933,mmu04974,mmu05146,mmu05165,mmu05200,mmu05222"	PI3K-Akt signaling pathway|Focal adhesion|ECM-receptor interaction|Relaxin signaling pathway|AGE-RAGE signaling pathway in diabetic complications|Protein digestion and absorption|Amoebiasis|Human papillomavirus infection|Pathways in cancer|Small cell lung cancer
Col5a1	1.491097241	0.576374345	0.018498387	Up	0.432441727	0.51330757	0.667253669	0.636461674	0.769898079	1.01940559	"collagen, type V, alpha 1"	"GO:0001568,GO:0003007,GO:0005201,GO:0005515,GO:0005576,GO:0005581,GO:0005588,GO:0005604,GO:0005615,GO:0007155,GO:0008201,GO:0016477,GO:0030020,GO:0030198,GO:0030199,GO:0031012,GO:0032964,GO:0035313,GO:0035989,GO:0043394,GO:0043588,GO:0045112,GO:0048407,GO:0048592,GO:0051128,GO:0062023,GO:0097435,GO:1903225"	"blood vessel development|heart morphogenesis|extracellular matrix structural constituent|protein binding|extracellular region|collagen trimer|collagen type V trimer|basement membrane|extracellular space|cell adhesion|heparin binding|cell migration|extracellular matrix structural constituent conferring tensile strength|extracellular matrix organization|collagen fibril organization|extracellular matrix|collagen biosynthetic process|wound healing, spreading of epidermal cells|tendon development|proteoglycan binding|skin development|integrin biosynthetic process|platelet-derived growth factor binding|eye morphogenesis|regulation of cellular component organization|collagen-containing extracellular matrix|supramolecular fiber organization|negative regulation of endodermal cell differentiation"	mmu04974	Protein digestion and absorption
Col6a1	1.27186315	0.346943448	0.036861501	Up	3.585395922	3.085984741	4.546786962	3.973407871	5.425128012	4.915628079	"collagen, type VI, alpha 1"	"GO:0005518,GO:0005576,GO:0005581,GO:0005615,GO:0007155,GO:0030020,GO:0031012,GO:0032991,GO:0042383,GO:0048407,GO:0062023,GO:0071230"	collagen binding|extracellular region|collagen trimer|extracellular space|cell adhesion|extracellular matrix structural constituent conferring tensile strength|extracellular matrix|protein-containing complex|sarcolemma|platelet-derived growth factor binding|collagen-containing extracellular matrix|cellular response to amino acid stimulus	"mmu04151,mmu04510,mmu04512,mmu04974,mmu05165"	PI3K-Akt signaling pathway|Focal adhesion|ECM-receptor interaction|Protein digestion and absorption|Human papillomavirus infection
Cpeb1	1.215321001	0.281337421	0.002124008	Up	10.33307001	10.73672435	11.45214251	12.7511525	13.59352638	13.4153275	cytoplasmic polyadenylation element binding protein 1	"GO:0000900,GO:0003676,GO:0003723,GO:0003729,GO:0003730,GO:0005515,GO:0005634,GO:0005654,GO:0005737,GO:0005813,GO:0005829,GO:0006397,GO:0006417,GO:0007130,GO:0008135,GO:0008285,GO:0010976,GO:0014069,GO:0016020,GO:0017148,GO:0030054,GO:0030335,GO:0030426,GO:0032869,GO:0035925,GO:0043005,GO:0043022,GO:0043025,GO:0045182,GO:0045202,GO:0045727,GO:0046872,GO:0048168,GO:0048471,GO:0051028,GO:0051770,GO:0071230,GO:0071456,GO:0072687,GO:1900365,GO:1990124,GO:2000766"	"translation repressor activity, mRNA regulatory element binding|nucleic acid binding|RNA binding|mRNA binding|mRNA 3'-UTR binding|protein binding|nucleus|nucleoplasm|cytoplasm|centrosome|cytosol|mRNA processing|regulation of translation|synaptonemal complex assembly|translation factor activity, RNA binding|negative regulation of cell population proliferation|positive regulation of neuron projection development|postsynaptic density|membrane|negative regulation of translation|cell junction|positive regulation of cell migration|growth cone|cellular response to insulin stimulus|mRNA 3'-UTR AU-rich region binding|neuron projection|ribosome binding|neuronal cell body|translation regulator activity|synapse|positive regulation of translation|metal ion binding|regulation of neuronal synaptic plasticity|perinuclear region of cytoplasm|mRNA transport|positive regulation of nitric-oxide synthase biosynthetic process|cellular response to amino acid stimulus|cellular response to hypoxia|meiotic spindle|positive regulation of mRNA polyadenylation|messenger ribonucleoprotein complex|negative regulation of cytoplasmic translation"	"mmu04114,mmu04914"	Oocyte meiosis|Progesterone-mediated oocyte maturation
Cryaa	1153.451714	10.1717419	1.75E-06	Up	0.043982815	0.088060885	249.231443	251.9163212	248.4284553	301.8276946	"crystallin, alpha A"	"GO:0001666,GO:0001934,GO:0002088,GO:0002089,GO:0005198,GO:0005212,GO:0005515,GO:0005634,GO:0005654,GO:0005737,GO:0005829,GO:0006457,GO:0006915,GO:0007005,GO:0007015,GO:0007017,GO:0007021,GO:0010629,GO:0030307,GO:0032991,GO:0042542,GO:0042802,GO:0043010,GO:0043066,GO:0043154,GO:0046872,GO:0048596,GO:0051082,GO:0060561,GO:0070141,GO:0070309"	response to hypoxia|positive regulation of protein phosphorylation|lens development in camera-type eye|lens morphogenesis in camera-type eye|structural molecule activity|structural constituent of eye lens|protein binding|nucleus|nucleoplasm|cytoplasm|cytosol|protein folding|apoptotic process|mitochondrion organization|actin filament organization|microtubule-based process|tubulin complex assembly|negative regulation of gene expression|positive regulation of cell growth|protein-containing complex|response to hydrogen peroxide|identical protein binding|camera-type eye development|negative regulation of apoptotic process|negative regulation of cysteine-type endopeptidase activity involved in apoptotic process|metal ion binding|embryonic camera-type eye morphogenesis|unfolded protein binding|apoptotic process involved in morphogenesis|response to UV-A|lens fiber cell morphogenesis	mmu04141	Protein processing in endoplasmic reticulum
Cryba1	627.4410824	9.293336184	7.95E-06	Up	0.065672219	0.065743332	143.089486	145.211138	145.4046127	171.3605156	"crystallin, beta A1"	"GO:0001818,GO:0002088,GO:0005212,GO:0005634,GO:0005737,GO:0007601,GO:0014067,GO:0032007,GO:0042802,GO:0043010,GO:0051898,GO:0070373,GO:2000210"	negative regulation of cytokine production|lens development in camera-type eye|structural constituent of eye lens|nucleus|cytoplasm|visual perception|negative regulation of phosphatidylinositol 3-kinase signaling|negative regulation of TOR signaling|identical protein binding|camera-type eye development|negative regulation of protein kinase B signaling|negative regulation of ERK1 and ERK2 cascade|positive regulation of anoikis		
Cryba2	57.71199111	5.850799201	0.000546357	Up	0.066001816	0.264293145	28.06160534	29.70118068	26.93170912	35.27324061	"crystallin, beta A2"	"GO:0002088,GO:0005212,GO:0007601,GO:0042802"	lens development in camera-type eye|structural constituent of eye lens|visual perception|identical protein binding		
Cryba4	14.62883159	3.87074264	0.00208628	Up	0.862351593	1.015629877	34.06907032	35.35016485	34.66780614	40.66457005	"crystallin, beta A4"	"GO:0002088,GO:0005212,GO:0007601,GO:0042802,GO:0043010"	lens development in camera-type eye|structural constituent of eye lens|visual perception|identical protein binding|camera-type eye development		
Crybb1	9.241344209	3.208102715	0.003458472	Up	4.885769088	6.304032466	109.8060782	119.8241622	114.5754893	134.6579842	"crystallin, beta B1"	"GO:0002088,GO:0005212,GO:0005515,GO:0007601"	lens development in camera-type eye|structural constituent of eye lens|protein binding|visual perception		
Crybb3	63.25661252	5.983144394	0.000183513	Up	0.459641771	0.409012886	76.92563188	79.91709621	83.51154746	93.84335627	"crystallin, beta B3"	"GO:0002088,GO:0005212,GO:0007601"	lens development in camera-type eye|structural constituent of eye lens|visual perception		
Cryga	120.22131	6.909548836	6.59E-05	Up	0.427670302	0.513760089	173.9353761	176.159831	172.2736298	204.519443	"crystallin, gamma A"	"GO:0001654,GO:0002088,GO:0005212,GO:0007601"	eye development|lens development in camera-type eye|structural constituent of eye lens|visual perception		
Crygb	1187.864577	10.21415466	0.001133294	Up	0	0	54.42583006	52.74247617	53.03544513	65.99865461	"crystallin, gamma B"	"GO:0001654,GO:0002088,GO:0005212,GO:0005634,GO:0005737,GO:0007601,GO:0070307,GO:0070309"	eye development|lens development in camera-type eye|structural constituent of eye lens|nucleus|cytoplasm|visual perception|lens fiber cell development|lens fiber cell morphogenesis		
Crygc	916.3364093	9.839733534	0.001531933	Up	0	0	39.41608895	44.13673754	38.41154339	44.96149027	"crystallin, gamma C"	"GO:0001654,GO:0002088,GO:0005212,GO:0005634,GO:0005737,GO:0007601,GO:0043010"	eye development|lens development in camera-type eye|structural constituent of eye lens|nucleus|cytoplasm|visual perception|camera-type eye development		
Crygd	2086.248211	11.0266951	0.000669938	Up	0	0	90.12576674	89.7743328	93.66449591	105.4769151	"crystallin, gamma D"	"GO:0001654,GO:0002088,GO:0005212,GO:0005634,GO:0005737,GO:0007601,GO:0034614,GO:0070306"	eye development|lens development in camera-type eye|structural constituent of eye lens|nucleus|cytoplasm|visual perception|cellular response to reactive oxygen species|lens fiber cell differentiation		
Cryge	2537.251006	11.30905053	0.000519256	Up	0	0	80.26378793	82.80426895	74.68617746	100.2296739	"crystallin, gamma E"	"GO:0001654,GO:0002088,GO:0005212,GO:0007601"	eye development|lens development in camera-type eye|structural constituent of eye lens|visual perception		
Crygf	1308.496935	10.35369483	0.000988151	Up	0	0	55.42887508	58.2800015	58.9201136	71.58225382	"crystallin, gamma F"	"GO:0001654,GO:0002088,GO:0005212,GO:0007601"	eye development|lens development in camera-type eye|structural constituent of eye lens|visual perception		
Crygn	5.068342216	2.341513939	0.00211102	Up	0.950144366	1.297054412	8.481362872	10.82987544	9.20205396	14.34522191	"crystallin, gamma N"	"GO:0002088,GO:0005212,GO:0007601"	lens development in camera-type eye|structural constituent of eye lens|visual perception		
Crygs	80.2814417	6.32699462	0.01295376	Up	0	0	2.328107437	2.947578356	2.161286971	2.935091162	"crystallin, gamma S"	"GO:0002009,GO:0002088,GO:0005212,GO:0007601"	morphogenesis of an epithelium|lens development in camera-type eye|structural constituent of eye lens|visual perception		
Cxcl12	0.792917844	-0.334756702	1.17E-05	Down	11.9222727	11.36894184	12.70911085	9.895565109	9.575523034	9.235835497	chemokine (C-X-C motif) ligand 12	"GO:0001569,GO:0001667,GO:0001764,GO:0001938,GO:0005125,GO:0005178,GO:0005576,GO:0005615,GO:0005634,GO:0005737,GO:0005886,GO:0006935,GO:0006952,GO:0006955,GO:0007281,GO:0007411,GO:0007420,GO:0008009,GO:0008045,GO:0008083,GO:0008284,GO:0008285,GO:0008344,GO:0008354,GO:0009897,GO:0010818,GO:0022029,GO:0030334,GO:0030335,GO:0031100,GO:0031640,GO:0033603,GO:0033622,GO:0038146,GO:0042098,GO:0042379,GO:0045236,GO:0045666,GO:0045785,GO:0048842,GO:0050921,GO:0050930,GO:0050965,GO:0050966,GO:0051897,GO:0051924,GO:0060326,GO:0061844,GO:0070098,GO:0070374,GO:0071542,GO:0090026,GO:0090280,GO:0098609,GO:1901741,GO:1902230,GO:1903237,GO:1990869,GO:2000406,GO:2000669"	branching involved in blood vessel morphogenesis|ameboidal-type cell migration|neuron migration|positive regulation of endothelial cell proliferation|cytokine activity|integrin binding|extracellular region|extracellular space|nucleus|cytoplasm|plasma membrane|chemotaxis|defense response|immune response|germ cell development|axon guidance|brain development|chemokine activity|motor neuron axon guidance|growth factor activity|positive regulation of cell population proliferation|negative regulation of cell population proliferation|adult locomotory behavior|germ cell migration|external side of plasma membrane|T cell chemotaxis|telencephalon cell migration|regulation of cell migration|positive regulation of cell migration|animal organ regeneration|killing of cells of other organism|positive regulation of dopamine secretion|integrin activation|chemokine (C-X-C motif) ligand 12 signaling pathway|T cell proliferation|chemokine receptor binding|CXCR chemokine receptor binding|positive regulation of neuron differentiation|positive regulation of cell adhesion|positive regulation of axon extension involved in axon guidance|positive regulation of chemotaxis|induction of positive chemotaxis|detection of temperature stimulus involved in sensory perception of pain|detection of mechanical stimulus involved in sensory perception of pain|positive regulation of protein kinase B signaling|regulation of calcium ion transport|cell chemotaxis|antimicrobial humoral immune response mediated by antimicrobial peptide|chemokine-mediated signaling pathway|positive regulation of ERK1 and ERK2 cascade|dopaminergic neuron differentiation|positive regulation of monocyte chemotaxis|positive regulation of calcium ion import|cell-cell adhesion|positive regulation of myoblast fusion|negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage|negative regulation of leukocyte tethering or rolling|cellular response to chemokine|positive regulation of T cell migration|negative regulation of dendritic cell apoptotic process	"mmu04060,mmu04061,mmu04062,mmu04064,mmu04360,mmu04670,mmu04672,mmu04810,mmu05163,mmu05200,mmu05323"	Cytokine-cytokine receptor interaction|Viral protein interaction with cytokine and cytokine receptor|Chemokine signaling pathway|NF-kappa B signaling pathway|Axon guidance|Leukocyte transendothelial migration|Intestinal immune network for IgA production|Regulation of actin cytoskeleton|Human cytomegalovirus infection|Pathways in cancer|Rheumatoid arthritis
Dbp	1.33961249	0.421815733	2.08E-10	Up	37.25282414	38.37566293	35.35036147	53.62058799	51.03580348	45.21204488	D site albumin promoter binding protein	"GO:0000977,GO:0000978,GO:0000981,GO:0001228,GO:0003677,GO:0003700,GO:0005634,GO:0005654,GO:0006355,GO:0006357,GO:0007623,GO:0045944,GO:0048511,GO:1990837"	"RNA polymerase II transcription regulatory region sequence-specific DNA binding|RNA polymerase II cis-regulatory region sequence-specific DNA binding|DNA-binding transcription factor activity, RNA polymerase II-specific|DNA-binding transcription activator activity, RNA polymerase II-specific|DNA binding|DNA-binding transcription factor activity|nucleus|nucleoplasm|regulation of transcription, DNA-templated|regulation of transcription by RNA polymerase II|circadian rhythm|positive regulation of transcription by RNA polymerase II|rhythmic process|sequence-specific double-stranded DNA binding"		
Ddit4	1.279263309	0.355313242	0.000108133	Up	22.41500004	24.9707222	26.1782676	26.70138637	33.289838	35.09651369	DNA-damage-inducible transcript 4	"GO:0001666,GO:0001764,GO:0005737,GO:0005739,GO:0005829,GO:0006915,GO:0007420,GO:0009968,GO:0010801,GO:0030182,GO:0032006,GO:0032007,GO:0032984,GO:0033137,GO:0042771,GO:0045820,GO:0048011,GO:0051607,GO:0071549,GO:0071889,GO:0072593,GO:1901216,GO:1902532"	response to hypoxia|neuron migration|cytoplasm|mitochondrion|cytosol|apoptotic process|brain development|negative regulation of signal transduction|negative regulation of peptidyl-threonine phosphorylation|neuron differentiation|regulation of TOR signaling|negative regulation of TOR signaling|protein-containing complex disassembly|negative regulation of peptidyl-serine phosphorylation|intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator|negative regulation of glycolytic process|neurotrophin TRK receptor signaling pathway|defense response to virus|cellular response to dexamethasone stimulus|14-3-3 protein binding|reactive oxygen species metabolic process|positive regulation of neuron death|negative regulation of intracellular signal transduction	"mmu04140,mmu04150,mmu04151,mmu05206"	Autophagy - animal|mTOR signaling pathway|PI3K-Akt signaling pathway|MicroRNAs in cancer
Dusp1	1.20740697	0.271912034	0.014414927	Up	14.81672791	20.20185623	23.96395541	14.53251889	29.34713692	29.70215528	dual specificity phosphatase 1	"GO:0000188,GO:0001706,GO:0004721,GO:0004722,GO:0004725,GO:0005634,GO:0005737,GO:0006470,GO:0007049,GO:0007162,GO:0008138,GO:0008285,GO:0008330,GO:0016311,GO:0016787,GO:0016791,GO:0017017,GO:0019838,GO:0035335,GO:0035556,GO:0035970,GO:0043065,GO:0043066,GO:0043407,GO:0043409,GO:0051019,GO:0070262,GO:0070373,GO:0090027,GO:0106306,GO:0106307,GO:1903753,GO:1990869,GO:2000279"	inactivation of MAPK activity|endoderm formation|phosphoprotein phosphatase activity|protein serine/threonine phosphatase activity|protein tyrosine phosphatase activity|nucleus|cytoplasm|protein dephosphorylation|cell cycle|negative regulation of cell adhesion|protein tyrosine/serine/threonine phosphatase activity|negative regulation of cell population proliferation|protein tyrosine/threonine phosphatase activity|dephosphorylation|hydrolase activity|phosphatase activity|MAP kinase tyrosine/serine/threonine phosphatase activity|growth factor binding|peptidyl-tyrosine dephosphorylation|intracellular signal transduction|peptidyl-threonine dephosphorylation|positive regulation of apoptotic process|negative regulation of apoptotic process|negative regulation of MAP kinase activity|negative regulation of MAPK cascade|mitogen-activated protein kinase binding|peptidyl-serine dephosphorylation|negative regulation of ERK1 and ERK2 cascade|negative regulation of monocyte chemotaxis|protein serine phosphatase activity|protein threonine phosphatase activity|negative regulation of p38MAPK cascade|cellular response to chemokine|negative regulation of DNA biosynthetic process	"mmu04010,mmu04726,mmu05012,mmu05418"	MAPK signaling pathway|Serotonergic synapse|Parkinson disease|Fluid shear stress and atherosclerosis
Egr2	1.449434928	0.535490565	0.010599296	Up	0.856367835	1.784860411	3.184279817	0.996070805	3.174643977	4.543492919	early growth response 2	"GO:0000976,GO:0000978,GO:0000981,GO:0001228,GO:0003677,GO:0003682,GO:0003700,GO:0005515,GO:0005634,GO:0005654,GO:0005737,GO:0006355,GO:0006357,GO:0006611,GO:0007622,GO:0008045,GO:0010467,GO:0014037,GO:0014040,GO:0016740,GO:0016925,GO:0021569,GO:0021612,GO:0021659,GO:0021660,GO:0021665,GO:0021666,GO:0030278,GO:0031625,GO:0031643,GO:0032868,GO:0035284,GO:0035914,GO:0042552,GO:0043231,GO:0043565,GO:0045444,GO:0045893,GO:0045944,GO:0046872,GO:0061629,GO:0061665,GO:0071310,GO:0071837,GO:1990837"	"transcription cis-regulatory region binding|RNA polymerase II cis-regulatory region sequence-specific DNA binding|DNA-binding transcription factor activity, RNA polymerase II-specific|DNA-binding transcription activator activity, RNA polymerase II-specific|DNA binding|chromatin binding|DNA-binding transcription factor activity|protein binding|nucleus|nucleoplasm|cytoplasm|regulation of transcription, DNA-templated|regulation of transcription by RNA polymerase II|protein export from nucleus|rhythmic behavior|motor neuron axon guidance|gene expression|Schwann cell differentiation|positive regulation of Schwann cell differentiation|transferase activity|protein sumoylation|rhombomere 3 development|facial nerve structural organization|rhombomere 3 structural organization|rhombomere 3 formation|rhombomere 5 structural organization|rhombomere 5 formation|regulation of ossification|ubiquitin protein ligase binding|positive regulation of myelination|response to insulin|brain segmentation|skeletal muscle cell differentiation|myelination|intracellular membrane-bounded organelle|sequence-specific DNA binding|fat cell differentiation|positive regulation of transcription, DNA-templated|positive regulation of transcription by RNA polymerase II|metal ion binding|RNA polymerase II-specific DNA-binding transcription factor binding|SUMO ligase activity|cellular response to organic substance|HMG box domain binding|sequence-specific double-stranded DNA binding"	"mmu04625,mmu05161,mmu05166,mmu05203"	C-type lectin receptor signaling pathway|Hepatitis B|Human T-cell leukemia virus 1 infection|Viral carcinogenesis
Eif2s3y	1.251512466	0.323672662	0.025293741	Up	1.872726513	2.059345609	3.049639439	2.352215608	3.347347762	2.999753834	"eukaryotic translation initiation factor 2, subunit 3, structural gene Y-linked"	"GO:0000049,GO:0000166,GO:0001731,GO:0003743,GO:0003924,GO:0005525,GO:0005829,GO:0005850,GO:0006412,GO:0006413,GO:0016787,GO:0045903"	tRNA binding|nucleotide binding|formation of translation preinitiation complex|translation initiation factor activity|GTPase activity|GTP binding|cytosol|eukaryotic translation initiation factor 2 complex|translation|translational initiation|hydrolase activity|positive regulation of translational fidelity	mmu03013	RNA transport
Eln	1.377749311	0.462313406	0.041336796	Up	1.826692428	2.067192709	1.29973578	2.341502195	2.235000486	2.536556891	elastin	"GO:0005201,GO:0005515,GO:0005576,GO:0005739,GO:0007519,GO:0030023,GO:0030198,GO:0030833,GO:0043149,GO:0050840,GO:0062023,GO:0071953"	extracellular matrix structural constituent|protein binding|extracellular region|mitochondrion|skeletal muscle tissue development|extracellular matrix constituent conferring elasticity|extracellular matrix organization|regulation of actin filament polymerization|stress fiber assembly|extracellular matrix binding|collagen-containing extracellular matrix|elastic fiber	mmu04974	Protein digestion and absorption
Fabp7	1.299574747	0.378039615	0.006713583	Up	27.06109094	20.59422824	18.16614432	35.29245071	30.25016312	21.09244331	"fatty acid binding protein 7, brain"	"GO:0001964,GO:0005504,GO:0005634,GO:0005737,GO:0005829,GO:0005911,GO:0008289,GO:0021846,GO:0022008,GO:0042995,GO:0043025,GO:0044297,GO:0050673,GO:0060134,GO:0071944"	startle response|fatty acid binding|nucleus|cytoplasm|cytosol|cell-cell junction|lipid binding|cell proliferation in forebrain|neurogenesis|cell projection|neuronal cell body|cell body|epithelial cell proliferation|prepulse inhibition|cell periphery	mmu03320	PPAR signaling pathway
Fam53a	1.229642046	0.298238402	0.035031644	Up	2.703257162	3.085226514	2.740797701	3.500331158	3.354055114	3.693439322	"family with sequence similarity 53, member A"	"GO:0005634,GO:0006606"	nucleus|protein import into nucleus		
Fgf15	12.28725614	3.619090879	0.016576585	Up	0	0.029110232	0.342630182	0.565252475	0.584504194	0.588186428	fibroblast growth factor 15	"GO:0001755,GO:0001934,GO:0005104,GO:0005515,GO:0005576,GO:0005615,GO:0005737,GO:0007507,GO:0008083,GO:0008284,GO:0008543,GO:0009617,GO:0009887,GO:0010628,GO:0010629,GO:0030154,GO:0030334,GO:0046326,GO:0046330,GO:0070374,GO:0070858"	neural crest cell migration|positive regulation of protein phosphorylation|fibroblast growth factor receptor binding|protein binding|extracellular region|extracellular space|cytoplasm|heart development|growth factor activity|positive regulation of cell population proliferation|fibroblast growth factor receptor signaling pathway|response to bacterium|animal organ morphogenesis|positive regulation of gene expression|negative regulation of gene expression|cell differentiation|regulation of cell migration|positive regulation of glucose import|positive regulation of JNK cascade|positive regulation of ERK1 and ERK2 cascade|negative regulation of bile acid biosynthetic process	"mmu04010,mmu04014,mmu04015,mmu04020,mmu04151,mmu04810,mmu05200,mmu05218,mmu05224,mmu05226"	MAPK signaling pathway|Ras signaling pathway|Rap1 signaling pathway|Calcium signaling pathway|PI3K-Akt signaling pathway|Regulation of actin cytoskeleton|Pathways in cancer|Melanoma|Breast cancer|Gastric cancer
Fos	1.227056176	0.295201298	0.009703016	Up	7.482709414	14.8068386	19.76422969	10.61814312	18.37484134	21.58807563	FBJ osteosarcoma oncogene	"GO:0000976,GO:0000978,GO:0000979,GO:0000981,GO:0001228,GO:0003677,GO:0003682,GO:0003690,GO:0003700,GO:0005515,GO:0005634,GO:0005654,GO:0005667,GO:0005737,GO:0005783,GO:0006355,GO:0006357,GO:0006366,GO:0007179,GO:0007399,GO:0008134,GO:0010468,GO:0016020,GO:0031668,GO:0032993,GO:0034614,GO:0035914,GO:0035976,GO:0035994,GO:0042493,GO:0042802,GO:0043005,GO:0043565,GO:0044877,GO:0045672,GO:0045893,GO:0045944,GO:0060395,GO:0061629,GO:0070412,GO:0071276,GO:0071277,GO:1901216,GO:1902895,GO:1990837"	"transcription cis-regulatory region binding|RNA polymerase II cis-regulatory region sequence-specific DNA binding|RNA polymerase II core promoter sequence-specific DNA binding|DNA-binding transcription factor activity, RNA polymerase II-specific|DNA-binding transcription activator activity, RNA polymerase II-specific|DNA binding|chromatin binding|double-stranded DNA binding|DNA-binding transcription factor activity|protein binding|nucleus|nucleoplasm|transcription regulator complex|cytoplasm|endoplasmic reticulum|regulation of transcription, DNA-templated|regulation of transcription by RNA polymerase II|transcription by RNA polymerase II|transforming growth factor beta receptor signaling pathway|nervous system development|transcription factor binding|regulation of gene expression|membrane|cellular response to extracellular stimulus|protein-DNA complex|cellular response to reactive oxygen species|skeletal muscle cell differentiation|transcription factor AP-1 complex|response to muscle stretch|response to drug|identical protein binding|neuron projection|sequence-specific DNA binding|protein-containing complex binding|positive regulation of osteoclast differentiation|positive regulation of transcription, DNA-templated|positive regulation of transcription by RNA polymerase II|SMAD protein signal transduction|RNA polymerase II-specific DNA-binding transcription factor binding|R-SMAD binding|cellular response to cadmium ion|cellular response to calcium ion|positive regulation of neuron death|positive regulation of pri-miRNA transcription by RNA polymerase II|sequence-specific double-stranded DNA binding"	"mmu01522,mmu04010,mmu04024,mmu04210,mmu04380,mmu04620,mmu04657,mmu04658,mmu04659,mmu04660,mmu04662,mmu04668,mmu04713,mmu04725,mmu04728,mmu04915,mmu04917,mmu04921,mmu04926,mmu04928,mmu04932,mmu04935,mmu05031,mmu05132,mmu05133,mmu05135,mmu05140,mmu05142,mmu05161,mmu05162,mmu05166,mmu05167,mmu05170,mmu05171,mmu05200,mmu05210,mmu05224,mmu05231,mmu05235,mmu05323,mmu05417,mmu05418"	"Endocrine resistance|MAPK signaling pathway|cAMP signaling pathway|Apoptosis|Osteoclast differentiation|Toll-like receptor signaling pathway|IL-17 signaling pathway|Th1 and Th2 cell differentiation|Th17 cell differentiation|T cell receptor signaling pathway|B cell receptor signaling pathway|TNF signaling pathway|Circadian entrainment|Cholinergic synapse|Dopaminergic synapse|Estrogen signaling pathway|Prolactin signaling pathway|Oxytocin signaling pathway|Relaxin signaling pathway|Parathyroid hormone synthesis, secretion and action|Non-alcoholic fatty liver disease|Growth hormone synthesis, secretion and action|Amphetamine addiction|Salmonella infection|Pertussis|Yersinia infection|Leishmaniasis|Chagas disease|Hepatitis B|Measles|Human T-cell leukemia virus 1 infection|Kaposi sarcoma-associated herpesvirus infection|Human immunodeficiency virus 1 infection|Coronavirus disease - COVID-19|Pathways in cancer|Colorectal cancer|Breast cancer|Choline metabolism in cancer|PD-L1 expression and PD-1 checkpoint pathway in cancer|Rheumatoid arthritis|Lipid and atherosclerosis|Fluid shear stress and atherosclerosis"
Foxe3	8.396335737	3.069759856	0.041948077	Up	0	0	0.222498769	0.188776934	0.227740819	0.275699886	forkhead box E3	"GO:0000978,GO:0000981,GO:0001654,GO:0002088,GO:0002930,GO:0003677,GO:0003700,GO:0005634,GO:0005667,GO:0006355,GO:0006357,GO:0006366,GO:0009653,GO:0030154,GO:0043010,GO:0043066,GO:0043565,GO:0048468,GO:0050679,GO:0051726,GO:0061072,GO:0061073,GO:0061303,GO:1902747,GO:2001111"	"RNA polymerase II cis-regulatory region sequence-specific DNA binding|DNA-binding transcription factor activity, RNA polymerase II-specific|eye development|lens development in camera-type eye|trabecular meshwork development|DNA binding|DNA-binding transcription factor activity|nucleus|transcription regulator complex|regulation of transcription, DNA-templated|regulation of transcription by RNA polymerase II|transcription by RNA polymerase II|anatomical structure morphogenesis|cell differentiation|camera-type eye development|negative regulation of apoptotic process|sequence-specific DNA binding|cell development|positive regulation of epithelial cell proliferation|regulation of cell cycle|iris morphogenesis|ciliary body morphogenesis|cornea development in camera-type eye|negative regulation of lens fiber cell differentiation|positive regulation of lens epithelial cell proliferation"		
Fzd4	1.330765781	0.412256675	0.00846086	Up	1.953675699	1.890111692	1.932636498	2.203509405	3.05517248	2.537763771	frizzled class receptor 4	"GO:0001540,GO:0001553,GO:0001568,GO:0001570,GO:0004888,GO:0004896,GO:0004930,GO:0005515,GO:0005615,GO:0005886,GO:0005911,GO:0007165,GO:0007166,GO:0007186,GO:0007223,GO:0007275,GO:0007605,GO:0009986,GO:0010812,GO:0016020,GO:0016021,GO:0016055,GO:0017147,GO:0019955,GO:0030165,GO:0030425,GO:0030947,GO:0031625,GO:0031987,GO:0034446,GO:0035426,GO:0035567,GO:0038023,GO:0042701,GO:0042803,GO:0042813,GO:0043507,GO:0044877,GO:0045202,GO:0045893,GO:0046982,GO:0051091,GO:0060070,GO:0061299,GO:0061301,GO:0061304,GO:0090090,GO:0098978,GO:0110135,GO:0150012,GO:1990830"	"amyloid-beta binding|luteinization|blood vessel development|vasculogenesis|transmembrane signaling receptor activity|cytokine receptor activity|G protein-coupled receptor activity|protein binding|extracellular space|plasma membrane|cell-cell junction|signal transduction|cell surface receptor signaling pathway|G protein-coupled receptor signaling pathway|Wnt signaling pathway, calcium modulating pathway|multicellular organism development|sensory perception of sound|cell surface|negative regulation of cell-substrate adhesion|membrane|integral component of membrane|Wnt signaling pathway|Wnt-protein binding|cytokine binding|PDZ domain binding|dendrite|regulation of vascular endothelial growth factor receptor signaling pathway|ubiquitin protein ligase binding|locomotion involved in locomotory behavior|substrate adhesion-dependent cell spreading|extracellular matrix-cell signaling|non-canonical Wnt signaling pathway|signaling receptor activity|progesterone secretion|protein homodimerization activity|Wnt-activated receptor activity|positive regulation of JUN kinase activity|protein-containing complex binding|synapse|positive regulation of transcription, DNA-templated|protein heterodimerization activity|positive regulation of DNA-binding transcription factor activity|canonical Wnt signaling pathway|retina vasculature morphogenesis in camera-type eye|cerebellum vasculature morphogenesis|retinal blood vessel morphogenesis|negative regulation of canonical Wnt signaling pathway|glutamatergic synapse|Norrin signaling pathway|positive regulation of neuron projection arborization|cellular response to leukemia inhibitory factor"	"mmu04150,mmu04310,mmu04390,mmu04550,mmu04916,mmu04934,mmu05010,mmu05022,mmu05165,mmu05200,mmu05205,mmu05217,mmu05224,mmu05225,mmu05226"	mTOR signaling pathway|Wnt signaling pathway|Hippo signaling pathway|Signaling pathways regulating pluripotency of stem cells|Melanogenesis|Cushing syndrome|Alzheimer disease|Pathways of neurodegeneration - multiple diseases|Human papillomavirus infection|Pathways in cancer|Proteoglycans in cancer|Basal cell carcinoma|Breast cancer|Hepatocellular carcinoma|Gastric cancer
Fzd7	1.26911355	0.343821155	0.048796128	Up	2.034568762	2.102474226	2.051452793	2.615359379	2.704434908	2.585223901	frizzled class receptor 7	"GO:0004888,GO:0004930,GO:0005109,GO:0005515,GO:0005546,GO:0005768,GO:0005886,GO:0006355,GO:0007165,GO:0007166,GO:0007186,GO:0007275,GO:0010812,GO:0014834,GO:0016020,GO:0016021,GO:0017147,GO:0019827,GO:0030165,GO:0033077,GO:0034446,GO:0035567,GO:0038031,GO:0042327,GO:0042666,GO:0042813,GO:0043231,GO:0045893,GO:0048103,GO:0055038,GO:0060054,GO:0060070,GO:0060231,GO:0060828,GO:2000726"	"transmembrane signaling receptor activity|G protein-coupled receptor activity|frizzled binding|protein binding|phosphatidylinositol-4,5-bisphosphate binding|endosome|plasma membrane|regulation of transcription, DNA-templated|signal transduction|cell surface receptor signaling pathway|G protein-coupled receptor signaling pathway|multicellular organism development|negative regulation of cell-substrate adhesion|skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration|membrane|integral component of membrane|Wnt-protein binding|stem cell population maintenance|PDZ domain binding|T cell differentiation in thymus|substrate adhesion-dependent cell spreading|non-canonical Wnt signaling pathway|non-canonical Wnt signaling pathway via JNK cascade|positive regulation of phosphorylation|negative regulation of ectodermal cell fate specification|Wnt-activated receptor activity|intracellular membrane-bounded organelle|positive regulation of transcription, DNA-templated|somatic stem cell division|recycling endosome membrane|positive regulation of epithelial cell proliferation involved in wound healing|canonical Wnt signaling pathway|mesenchymal to epithelial transition|regulation of canonical Wnt signaling pathway|negative regulation of cardiac muscle cell differentiation"	"mmu04150,mmu04310,mmu04390,mmu04550,mmu04916,mmu04934,mmu05010,mmu05022,mmu05165,mmu05200,mmu05205,mmu05217,mmu05224,mmu05225,mmu05226"	mTOR signaling pathway|Wnt signaling pathway|Hippo signaling pathway|Signaling pathways regulating pluripotency of stem cells|Melanogenesis|Cushing syndrome|Alzheimer disease|Pathways of neurodegeneration - multiple diseases|Human papillomavirus infection|Pathways in cancer|Proteoglycans in cancer|Basal cell carcinoma|Breast cancer|Hepatocellular carcinoma|Gastric cancer
Gja3	7.419113535	2.891246818	0.004736232	Up	0.107317471	0.071622454	1.159129205	1.529814214	1.402154213	1.656624932	"gap junction protein, alpha 3"	"GO:0005243,GO:0005886,GO:0005887,GO:0005921,GO:0005922,GO:0007154,GO:0007267,GO:0007601,GO:0009268,GO:0016020,GO:0016021,GO:0030054,GO:0042542,GO:0042802,GO:0045121,GO:0055077,GO:1990349"	gap junction channel activity|plasma membrane|integral component of plasma membrane|gap junction|connexin complex|cell communication|cell-cell signaling|visual perception|response to pH|membrane|integral component of membrane|cell junction|response to hydrogen peroxide|identical protein binding|membrane raft|gap junction hemi-channel activity|gap junction-mediated intercellular transport		
Gja8	825.536469	9.689188139	0.00161112	Up	0	0	3.200896278	3.549779058	3.177716457	3.920348761	"gap junction protein, alpha 8"	"GO:0002088,GO:0005243,GO:0005886,GO:0005887,GO:0005921,GO:0005922,GO:0007154,GO:0007267,GO:0016020,GO:0016021,GO:0030054,GO:0042802,GO:0043010,GO:1990349"	lens development in camera-type eye|gap junction channel activity|plasma membrane|integral component of plasma membrane|gap junction|connexin complex|cell communication|cell-cell signaling|membrane|integral component of membrane|cell junction|identical protein binding|camera-type eye development|gap junction-mediated intercellular transport		
Gje1	12.11180624	3.598342126	0.03253298	Up	0	0.028342524	0.472591764	0.742966272	0.512180451	0.482252223	"gap junction protein, epsilon 1"	"GO:0000902,GO:0002088,GO:0005243,GO:0005886,GO:0005922,GO:0007154,GO:0007267,GO:0007275,GO:0016020,GO:0016021,GO:0035265"	cell morphogenesis|lens development in camera-type eye|gap junction channel activity|plasma membrane|connexin complex|cell communication|cell-cell signaling|multicellular organism development|membrane|integral component of membrane|organ growth		
Gm6710	2.853487374	1.51272618	0.007166108	Up	0.179345611	0.207161326	0.094823105	0.657022616	0.402093818	0.323114048	predicted gene 6710			mmu05168	Herpes simplex virus 1 infection
Gpr4	0.693503419	-0.528025099	0.047326231	Down	2.006372812	2.191140463	1.952154469	1.560049793	1.246550449	1.495186731	G protein-coupled receptor 4	"GO:0004930,GO:0005886,GO:0005887,GO:0007165,GO:0007186,GO:0007189,GO:0007200,GO:0010447,GO:0016020,GO:0016021,GO:0016525,GO:0030155,GO:0035025,GO:0043114,GO:0050729,GO:0051482,GO:0060055,GO:0072144"	G protein-coupled receptor activity|plasma membrane|integral component of plasma membrane|signal transduction|G protein-coupled receptor signaling pathway|adenylate cyclase-activating G protein-coupled receptor signaling pathway|phospholipase C-activating G protein-coupled receptor signaling pathway|response to acidic pH|membrane|integral component of membrane|negative regulation of angiogenesis|regulation of cell adhesion|positive regulation of Rho protein signal transduction|regulation of vascular permeability|positive regulation of inflammatory response|positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway|angiogenesis involved in wound healing|glomerular mesangial cell development		
H1f2	0.725871124	-0.46221467	0.005086977	Down	22.41995197	21.1367987	18.30956617	16.43118777	14.58438741	14.13556097	"H1.2 linker histone, cluster member"	"GO:0000122,GO:0000786,GO:0000791,GO:0003677,GO:0003690,GO:0005515,GO:0005634,GO:0005694,GO:0006334,GO:0006357,GO:0016584,GO:0030261,GO:0031490,GO:0031492,GO:0031936,GO:0035327,GO:0045910,GO:0080182,GO:0098532"	negative regulation of transcription by RNA polymerase II|nucleosome|euchromatin|DNA binding|double-stranded DNA binding|protein binding|nucleus|chromosome|nucleosome assembly|regulation of transcription by RNA polymerase II|nucleosome positioning|chromosome condensation|chromatin DNA binding|nucleosomal DNA binding|negative regulation of chromatin silencing|transcriptionally active chromatin|negative regulation of DNA recombination|histone H3-K4 trimethylation|histone H3-K27 trimethylation		
Hbb-bt	1.313852695	0.393803535	0.022718617	Up	17.36748732	15.38018299	27.79342613	29.54009436	20.14034452	29.06746567	"hemoglobin, beta adult t chain"	"GO:0004601,GO:0005344,GO:0005615,GO:0005833,GO:0019825,GO:0020037,GO:0030492,GO:0031720,GO:0031721,GO:0031722,GO:0031838,GO:0042744,GO:0043177,GO:0044877"	peroxidase activity|oxygen carrier activity|extracellular space|hemoglobin complex|oxygen binding|heme binding|hemoglobin binding|haptoglobin binding|hemoglobin alpha binding|hemoglobin beta binding|haptoglobin-hemoglobin complex|hydrogen peroxide catabolic process|organic acid binding|protein-containing complex binding	"mmu05143,mmu05144"	African trypanosomiasis|Malaria
Hexdc	1.25450307	0.327116001	0.03527685	Up	2.853691081	3.580172169	3.126749702	4.094928456	4.037447411	3.898593777	"hexosaminidase (glycosyl hydrolase family 20, catalytic domain) containing"	"GO:0004553,GO:0004563,GO:0005634,GO:0005737,GO:0005975,GO:0008152,GO:0015929,GO:0016787,GO:0016798,GO:0102148,GO:1903561"	"hydrolase activity, hydrolyzing O-glycosyl compounds|beta-N-acetylhexosaminidase activity|nucleus|cytoplasm|carbohydrate metabolic process|metabolic process|hexosaminidase activity|hydrolase activity|hydrolase activity, acting on glycosyl bonds|N-acetyl-beta-D-galactosaminidase activity|extracellular vesicle"	"mmu00511,mmu00513"	Other glycan degradation|Various types of N-glycan biosynthesis
Hif3a	2.535536714	1.342291165	2.90E-06	Up	0.278703225	0.372006694	0.364879499	0.736241157	1.07733469	0.791218597	"hypoxia inducible factor 3, alpha subunit"	"GO:0000785,GO:0000977,GO:0000978,GO:0000981,GO:0001525,GO:0001666,GO:0003677,GO:0003700,GO:0005515,GO:0005634,GO:0005654,GO:0005737,GO:0005739,GO:0005829,GO:0005886,GO:0006355,GO:0006357,GO:0006366,GO:0006915,GO:0007275,GO:0016607,GO:0045944,GO:0046983,GO:0071456"	"chromatin|RNA polymerase II transcription regulatory region sequence-specific DNA binding|RNA polymerase II cis-regulatory region sequence-specific DNA binding|DNA-binding transcription factor activity, RNA polymerase II-specific|angiogenesis|response to hypoxia|DNA binding|DNA-binding transcription factor activity|protein binding|nucleus|nucleoplasm|cytoplasm|mitochondrion|cytosol|plasma membrane|regulation of transcription, DNA-templated|regulation of transcription by RNA polymerase II|transcription by RNA polymerase II|apoptotic process|multicellular organism development|nuclear speck|positive regulation of transcription by RNA polymerase II|protein dimerization activity|cellular response to hypoxia"		
Hmga2	15.72676152	3.975149715	0.02448997	Up	0	0	0.013531962	0.053578293	0.055403096	0.132044499	high mobility group AT-hook 2	"GO:0000122,GO:0000228,GO:0000785,GO:0001228,GO:0003677,GO:0003680,GO:0003712,GO:0005515,GO:0005634,GO:0006355,GO:0007049,GO:0007165,GO:0007283,GO:0008284,GO:0008584,GO:0010564,GO:0010628,GO:0019899,GO:0021846,GO:0021983,GO:0030178,GO:0030261,GO:0030325,GO:0033144,GO:0035019,GO:0040008,GO:0040018,GO:0045766,GO:0045944,GO:0046426,GO:0048712,GO:0051091,GO:0051301,GO:0051321,GO:0060123,GO:0060428,GO:0060441,GO:0060501,GO:0060612,GO:0060613,GO:0071864,GO:0090276,GO:2000648,GO:2000773"	"negative regulation of transcription by RNA polymerase II|nuclear chromosome|chromatin|DNA-binding transcription activator activity, RNA polymerase II-specific|DNA binding|minor groove of adenine-thymine-rich DNA binding|transcription coregulator activity|protein binding|nucleus|regulation of transcription, DNA-templated|cell cycle|signal transduction|spermatogenesis|positive regulation of cell population proliferation|male gonad development|regulation of cell cycle process|positive regulation of gene expression|enzyme binding|cell proliferation in forebrain|pituitary gland development|negative regulation of Wnt signaling pathway|chromosome condensation|adrenal gland development|negative regulation of intracellular steroid hormone receptor signaling pathway|somatic stem cell population maintenance|regulation of growth|positive regulation of multicellular organism growth|positive regulation of angiogenesis|positive regulation of transcription by RNA polymerase II|negative regulation of receptor signaling pathway via JAK-STAT|negative regulation of astrocyte differentiation|positive regulation of DNA-binding transcription factor activity|cell division|meiotic cell cycle|regulation of growth hormone secretion|lung epithelium development|epithelial tube branching involved in lung morphogenesis|positive regulation of epithelial cell proliferation involved in lung morphogenesis|adipose tissue development|fat pad development|positive regulation of cell proliferation in bone marrow|regulation of peptide hormone secretion|positive regulation of stem cell proliferation|negative regulation of cellular senescence"	"mmu05202,mmu05206"	Transcriptional misregulation in cancer|MicroRNAs in cancer
Hmx1	8.756541314	3.130361142	0.026640826	Up	0	0	0.146321529	0.248290181	0.106977751	0.1813081	H6 homeobox 1	"GO:0000122,GO:0000977,GO:0000981,GO:0001227,GO:0003677,GO:0005634,GO:0006355,GO:0006357,GO:0007275,GO:0043565,GO:0045892,GO:1990837"	"negative regulation of transcription by RNA polymerase II|RNA polymerase II transcription regulatory region sequence-specific DNA binding|DNA-binding transcription factor activity, RNA polymerase II-specific|DNA-binding transcription repressor activity, RNA polymerase II-specific|DNA binding|nucleus|regulation of transcription, DNA-templated|regulation of transcription by RNA polymerase II|multicellular organism development|sequence-specific DNA binding|negative regulation of transcription, DNA-templated|sequence-specific double-stranded DNA binding"		
Hook1	1.303836202	0.382762638	0.000129626	Up	6.065162274	5.964423993	6.727237293	7.249298207	8.914641794	8.50150725	hook microtubule tethering protein 1	"GO:0003779,GO:0005515,GO:0005737,GO:0005813,GO:0005856,GO:0005874,GO:0007030,GO:0007032,GO:0007040,GO:0007275,GO:0007283,GO:0007286,GO:0008017,GO:0008333,GO:0015031,GO:0015630,GO:0030154,GO:0030705,GO:0030897,GO:0031122,GO:0042802,GO:0042803,GO:0045022,GO:0051959,GO:0070695,GO:1905198,GO:1905719"	actin binding|protein binding|cytoplasm|centrosome|cytoskeleton|microtubule|Golgi organization|endosome organization|lysosome organization|multicellular organism development|spermatogenesis|spermatid development|microtubule binding|endosome to lysosome transport|protein transport|microtubule cytoskeleton|cell differentiation|cytoskeleton-dependent intracellular transport|HOPS complex|cytoplasmic microtubule organization|identical protein binding|protein homodimerization activity|early endosome to late endosome transport|dynein light intermediate chain binding|FHF complex|manchette assembly|protein localization to perinuclear region of cytoplasm		
Hspe1	0.827408906	-0.273327608	0.001125081	Down	81.85041586	92.8413984	81.71428694	71.69775006	71.73030904	69.7831682	heat shock protein 1 (chaperonin 10)	"GO:0005524,GO:0005739,GO:0005759,GO:0006457,GO:0046872,GO:0051082,GO:0051085,GO:0051087"	ATP binding|mitochondrion|mitochondrial matrix|protein folding|metal ion binding|unfolded protein binding|chaperone cofactor-dependent protein refolding|chaperone binding		
Ifit3	0.669150773	-0.579596778	0.00424895	Down	4.419632418	3.382221946	3.876755593	2.882819285	2.645394393	2.321198981	interferon-induced protein with tetratricopeptide repeats 3	"GO:0002376,GO:0003723,GO:0005515,GO:0005737,GO:0005739,GO:0005829,GO:0009617,GO:0035457,GO:0035458,GO:0035634,GO:0042802,GO:0045087,GO:0051607"	immune system process|RNA binding|protein binding|cytoplasm|mitochondrion|cytosol|response to bacterium|cellular response to interferon-alpha|cellular response to interferon-beta|response to stilbenoid|identical protein binding|innate immune response|defense response to virus		
Ifit3b	0.687082423	-0.541444919	0.036523731	Down	2.757438763	2.713237926	2.892669125	1.992856862	2.155477059	1.655959498	interferon-induced protein with tetratricopeptide repeats 3B	"GO:0003723,GO:0005737,GO:0005739,GO:0005829,GO:0042802,GO:0051607"	RNA binding|cytoplasm|mitochondrion|cytosol|identical protein binding|defense response to virus		
Ifrd2	1.429676474	0.515688712	0.041039734	Up	2.391065781	2.526635792	1.930409592	3.072789536	3.52456029	3.224331055	interferon-related developmental regulator 2				
Igf2bp1	14.83573118	3.891004127	0.012427554	Up	0	0	0.012324386	0.0426974	0.025229494	0.080174001	insulin-like growth factor 2 mRNA binding protein 1	"GO:0003676,GO:0003723,GO:0003729,GO:0003730,GO:0005634,GO:0005654,GO:0005737,GO:0005829,GO:0006403,GO:0006417,GO:0007399,GO:0010468,GO:0010494,GO:0010610,GO:0017148,GO:0022013,GO:0030054,GO:0030424,GO:0030425,GO:0042995,GO:0043025,GO:0043197,GO:0045182,GO:0045202,GO:0048027,GO:0051028,GO:0051252,GO:0070934,GO:0070937,GO:0097150,GO:0140059,GO:1990904"	nucleic acid binding|RNA binding|mRNA binding|mRNA 3'-UTR binding|nucleus|nucleoplasm|cytoplasm|cytosol|RNA localization|regulation of translation|nervous system development|regulation of gene expression|cytoplasmic stress granule|regulation of mRNA stability involved in response to stress|negative regulation of translation|pallium cell proliferation in forebrain|cell junction|axon|dendrite|cell projection|neuronal cell body|dendritic spine|translation regulator activity|synapse|mRNA 5'-UTR binding|mRNA transport|regulation of RNA metabolic process|CRD-mediated mRNA stabilization|CRD-mediated mRNA stability complex|neuronal stem cell population maintenance|dendrite arborization|ribonucleoprotein complex	mmu05206	MicroRNAs in cancer
Inhba	0.762687399	-0.390836232	0.039842648	Down	0.906447154	0.793472543	0.902462689	0.651535364	0.644064876	0.700187556	inhibin beta-A	"GO:0000082,GO:0001541,GO:0001707,GO:0001942,GO:0002244,GO:0005102,GO:0005125,GO:0005179,GO:0005576,GO:0005615,GO:0006357,GO:0008083,GO:0008285,GO:0008584,GO:0010628,GO:0010862,GO:0017046,GO:0021773,GO:0030308,GO:0032270,GO:0032924,GO:0034711,GO:0035987,GO:0042476,GO:0042493,GO:0042541,GO:0042701,GO:0042802,GO:0043509,GO:0043512,GO:0044877,GO:0045648,GO:0045786,GO:0045893,GO:0045944,GO:0046880,GO:0048333,GO:0048471,GO:0051726,GO:0051799,GO:0060021,GO:0060279,GO:0060395,GO:0061029,GO:0070699,GO:0071372,GO:0071397,GO:0097154,GO:0097191,GO:2001241"	"G1/S transition of mitotic cell cycle|ovarian follicle development|mesoderm formation|hair follicle development|hematopoietic progenitor cell differentiation|signaling receptor binding|cytokine activity|hormone activity|extracellular region|extracellular space|regulation of transcription by RNA polymerase II|growth factor activity|negative regulation of cell population proliferation|male gonad development|positive regulation of gene expression|positive regulation of pathway-restricted SMAD protein phosphorylation|peptide hormone binding|striatal medium spiny neuron differentiation|negative regulation of cell growth|positive regulation of cellular protein metabolic process|activin receptor signaling pathway|inhibin binding|endodermal cell differentiation|odontogenesis|response to drug|hemoglobin biosynthetic process|progesterone secretion|identical protein binding|activin A complex|inhibin A complex|protein-containing complex binding|positive regulation of erythrocyte differentiation|negative regulation of cell cycle|positive regulation of transcription, DNA-templated|positive regulation of transcription by RNA polymerase II|regulation of follicle-stimulating hormone secretion|mesodermal cell differentiation|perinuclear region of cytoplasm|regulation of cell cycle|negative regulation of hair follicle development|roof of mouth development|positive regulation of ovulation|SMAD protein signal transduction|eyelid development in camera-type eye|type II activin receptor binding|cellular response to follicle-stimulating hormone stimulus|cellular response to cholesterol|GABAergic neuron differentiation|extrinsic apoptotic signaling pathway|positive regulation of extrinsic apoptotic signaling pathway in absence of ligand"	"mmu04060,mmu04350,mmu04550"	Cytokine-cytokine receptor interaction|TGF-beta signaling pathway|Signaling pathways regulating pluripotency of stem cells
Ints6l	1.250356021	0.32233894	0.021882457	Up	4.658272703	4.702286164	5.669688567	5.18333313	7.576848281	6.28532324	integrator complex subunit 6 like	"GO:0032039,GO:0034472"	integrator complex|snRNA 3'-end processing		
Jph1	1.234318303	0.303714481	0.013422543	Up	5.044613928	4.439268127	4.717960119	5.792567576	5.321881632	6.565217747	junctophilin 1	"GO:0005654,GO:0005783,GO:0005789,GO:0005886,GO:0007517,GO:0008307,GO:0014701,GO:0016020,GO:0016021,GO:0016529,GO:0030018,GO:0030314"	nucleoplasm|endoplasmic reticulum|endoplasmic reticulum membrane|plasma membrane|muscle organ development|structural constituent of muscle|junctional sarcoplasmic reticulum membrane|membrane|integral component of membrane|sarcoplasmic reticulum|Z disc|junctional membrane complex		
Junb	1.232116009	0.301138098	9.01E-05	Up	28.76036297	36.28989064	45.36349121	36.73370012	47.84015938	51.52750334	jun B proto-oncogene	"GO:0000977,GO:0000978,GO:0000981,GO:0001228,GO:0001570,GO:0001649,GO:0001701,GO:0001829,GO:0003677,GO:0003690,GO:0003700,GO:0005515,GO:0005634,GO:0005654,GO:0005667,GO:0006355,GO:0006357,GO:0006366,GO:0008134,GO:0009987,GO:0030316,GO:0033687,GO:0035976,GO:0042127,GO:0043565,GO:0045597,GO:0045944,GO:0046697,GO:0051726,GO:0060136,GO:0060716,GO:0071277,GO:1990837"	"RNA polymerase II transcription regulatory region sequence-specific DNA binding|RNA polymerase II cis-regulatory region sequence-specific DNA binding|DNA-binding transcription factor activity, RNA polymerase II-specific|DNA-binding transcription activator activity, RNA polymerase II-specific|vasculogenesis|osteoblast differentiation|in utero embryonic development|trophectodermal cell differentiation|DNA binding|double-stranded DNA binding|DNA-binding transcription factor activity|protein binding|nucleus|nucleoplasm|transcription regulator complex|regulation of transcription, DNA-templated|regulation of transcription by RNA polymerase II|transcription by RNA polymerase II|transcription factor binding|cellular process|osteoclast differentiation|osteoblast proliferation|transcription factor AP-1 complex|regulation of cell population proliferation|sequence-specific DNA binding|positive regulation of cell differentiation|positive regulation of transcription by RNA polymerase II|decidualization|regulation of cell cycle|embryonic process involved in female pregnancy|labyrinthine layer blood vessel development|cellular response to calcium ion|sequence-specific double-stranded DNA binding"	"mmu04380,mmu04668,mmu04935"	"Osteoclast differentiation|TNF signaling pathway|Growth hormone synthesis, secretion and action"
Kcna5	1.366196091	0.45016457	0.021694981	Up	2.800849101	2.611115129	2.217318964	3.521899129	3.765004503	3.18677645	"potassium voltage-gated channel, shaker-related subfamily, member 5"	"GO:0005102,GO:0005216,GO:0005244,GO:0005249,GO:0005251,GO:0005267,GO:0005515,GO:0005783,GO:0005794,GO:0005886,GO:0005887,GO:0006811,GO:0006813,GO:0007219,GO:0008076,GO:0009986,GO:0014704,GO:0015271,GO:0016020,GO:0016021,GO:0019229,GO:0019870,GO:0019901,GO:0030018,GO:0034705,GO:0034765,GO:0042391,GO:0043266,GO:0043267,GO:0045121,GO:0046691,GO:0048471,GO:0051259,GO:0051260,GO:0051393,GO:0051481,GO:0055075,GO:0055085,GO:0060081,GO:0060372,GO:0071805,GO:0086014,GO:0086050,GO:0086052,GO:0086087,GO:0086089,GO:0086090,GO:0086091,GO:0097110,GO:0097623,GO:0098914,GO:1900087,GO:2000288"	signaling receptor binding|ion channel activity|voltage-gated ion channel activity|voltage-gated potassium channel activity|delayed rectifier potassium channel activity|potassium channel activity|protein binding|endoplasmic reticulum|Golgi apparatus|plasma membrane|integral component of plasma membrane|ion transport|potassium ion transport|Notch signaling pathway|voltage-gated potassium channel complex|cell surface|intercalated disc|outward rectifier potassium channel activity|membrane|integral component of membrane|regulation of vasoconstriction|potassium channel inhibitor activity|protein kinase binding|Z disc|potassium channel complex|regulation of ion transmembrane transport|regulation of membrane potential|regulation of potassium ion transport|negative regulation of potassium ion transport|membrane raft|intracellular canaliculus|perinuclear region of cytoplasm|protein complex oligomerization|protein homooligomerization|alpha-actinin binding|negative regulation of cytosolic calcium ion concentration|potassium ion homeostasis|transmembrane transport|membrane hyperpolarization|regulation of atrial cardiac muscle cell membrane repolarization|potassium ion transmembrane transport|atrial cardiac muscle cell action potential|membrane repolarization during bundle of His cell action potential|membrane repolarization during SA node cell action potential|voltage-gated potassium channel activity involved in bundle of His cell action potential repolarization|voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization|voltage-gated potassium channel activity involved in SA node cell action potential repolarization|regulation of heart rate by cardiac conduction|scaffold protein binding|potassium ion export across plasma membrane|membrane repolarization during atrial cardiac muscle cell action potential|positive regulation of G1/S transition of mitotic cell cycle|positive regulation of myoblast proliferation		
Kcnj10	0.798431869	-0.324758789	2.13E-05	Down	23.92451103	25.46066711	25.30205282	18.17292439	19.98646225	21.99828719	"potassium inwardly-rectifying channel, subfamily J, member 10"	"GO:0000166,GO:0005102,GO:0005242,GO:0005244,GO:0005267,GO:0005515,GO:0005524,GO:0005886,GO:0005887,GO:0005902,GO:0006811,GO:0006813,GO:0007601,GO:0007628,GO:0014003,GO:0016020,GO:0016021,GO:0016323,GO:0016324,GO:0022010,GO:0034765,GO:0042391,GO:0042802,GO:0044297,GO:0048169,GO:0051930,GO:0051935,GO:0051938,GO:0055075,GO:0060075,GO:0060081,GO:0071805,GO:0097449,GO:0097546,GO:1905515,GO:1990573"	nucleotide binding|signaling receptor binding|inward rectifier potassium channel activity|voltage-gated ion channel activity|potassium channel activity|protein binding|ATP binding|plasma membrane|integral component of plasma membrane|microvillus|ion transport|potassium ion transport|visual perception|adult walking behavior|oligodendrocyte development|membrane|integral component of membrane|basolateral plasma membrane|apical plasma membrane|central nervous system myelination|regulation of ion transmembrane transport|regulation of membrane potential|identical protein binding|cell body|regulation of long-term neuronal synaptic plasticity|regulation of sensory perception of pain|glutamate reuptake|L-glutamate import|potassium ion homeostasis|regulation of resting membrane potential|membrane hyperpolarization|potassium ion transmembrane transport|astrocyte projection|ciliary base|non-motile cilium assembly|potassium ion import across plasma membrane	"mmu04971,mmu05016"	Gastric acid secretion|Huntington disease
Kdr	0.824176898	-0.278974069	0.046957254	Down	2.575509845	2.41044076	2.74622918	2.320699064	2.022251856	2.070693155	kinase insert domain protein receptor	"GO:0000166,GO:0001525,GO:0001541,GO:0001569,GO:0001570,GO:0001666,GO:0001934,GO:0001936,GO:0001938,GO:0001945,GO:0002042,GO:0002053,GO:0002244,GO:0003157,GO:0003158,GO:0003416,GO:0004672,GO:0004713,GO:0004714,GO:0005021,GO:0005178,GO:0005515,GO:0005524,GO:0005576,GO:0005634,GO:0005737,GO:0005768,GO:0005769,GO:0005783,GO:0005794,GO:0005886,GO:0005887,GO:0006468,GO:0007169,GO:0007204,GO:0007275,GO:0008284,GO:0008360,GO:0008584,GO:0009897,GO:0009986,GO:0010595,GO:0010629,GO:0014068,GO:0016020,GO:0016021,GO:0016239,GO:0016301,GO:0016310,GO:0016477,GO:0016740,GO:0018108,GO:0019838,GO:0030054,GO:0030097,GO:0030154,GO:0030324,GO:0030335,GO:0030513,GO:0030949,GO:0031410,GO:0032008,GO:0033674,GO:0035162,GO:0035584,GO:0035924,GO:0036324,GO:0038033,GO:0038083,GO:0038084,GO:0038085,GO:0042493,GO:0042802,GO:0043005,GO:0043025,GO:0043066,GO:0043129,GO:0043235,GO:0043410,GO:0043491,GO:0043524,GO:0043536,GO:0045121,GO:0045165,GO:0045296,GO:0045446,GO:0045766,GO:0046777,GO:0048010,GO:0048170,GO:0048286,GO:0048469,GO:0048597,GO:0048754,GO:0048812,GO:0050679,GO:0050850,GO:0050927,GO:0051770,GO:0051894,GO:0051901,GO:0055074,GO:0060837,GO:0061042,GO:0070371,GO:0070374,GO:0071944,GO:0090050,GO:0090141,GO:0097443,GO:1901532,GO:1903010,GO:1904881,GO:2000352,GO:2001214"	nucleotide binding|angiogenesis|ovarian follicle development|branching involved in blood vessel morphogenesis|vasculogenesis|response to hypoxia|positive regulation of protein phosphorylation|regulation of endothelial cell proliferation|positive regulation of endothelial cell proliferation|lymph vessel development|cell migration involved in sprouting angiogenesis|positive regulation of mesenchymal cell proliferation|hematopoietic progenitor cell differentiation|endocardium development|endothelium development|endochondral bone growth|protein kinase activity|protein tyrosine kinase activity|transmembrane receptor protein tyrosine kinase activity|vascular endothelial growth factor-activated receptor activity|integrin binding|protein binding|ATP binding|extracellular region|nucleus|cytoplasm|endosome|early endosome|endoplasmic reticulum|Golgi apparatus|plasma membrane|integral component of plasma membrane|protein phosphorylation|transmembrane receptor protein tyrosine kinase signaling pathway|positive regulation of cytosolic calcium ion concentration|multicellular organism development|positive regulation of cell population proliferation|regulation of cell shape|male gonad development|external side of plasma membrane|cell surface|positive regulation of endothelial cell migration|negative regulation of gene expression|positive regulation of phosphatidylinositol 3-kinase signaling|membrane|integral component of membrane|positive regulation of macroautophagy|kinase activity|phosphorylation|cell migration|transferase activity|peptidyl-tyrosine phosphorylation|growth factor binding|cell junction|hemopoiesis|cell differentiation|lung development|positive regulation of cell migration|positive regulation of BMP signaling pathway|positive regulation of vascular endothelial growth factor receptor signaling pathway|cytoplasmic vesicle|positive regulation of TOR signaling|positive regulation of kinase activity|embryonic hemopoiesis|calcium-mediated signaling using intracellular calcium source|cellular response to vascular endothelial growth factor stimulus|vascular endothelial growth factor receptor-2 signaling pathway|positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway|peptidyl-tyrosine autophosphorylation|vascular endothelial growth factor signaling pathway|vascular endothelial growth factor binding|response to drug|identical protein binding|neuron projection|neuronal cell body|negative regulation of apoptotic process|surfactant homeostasis|receptor complex|positive regulation of MAPK cascade|protein kinase B signaling|negative regulation of neuron apoptotic process|positive regulation of blood vessel endothelial cell migration|membrane raft|cell fate commitment|cadherin binding|endothelial cell differentiation|positive regulation of angiogenesis|protein autophosphorylation|vascular endothelial growth factor receptor signaling pathway|positive regulation of long-term neuronal synaptic plasticity|lung alveolus development|cell maturation|post-embryonic camera-type eye morphogenesis|branching morphogenesis of an epithelial tube|neuron projection morphogenesis|positive regulation of epithelial cell proliferation|positive regulation of calcium-mediated signaling|positive regulation of positive chemotaxis|positive regulation of nitric-oxide synthase biosynthetic process|positive regulation of focal adhesion assembly|positive regulation of mitochondrial depolarization|calcium ion homeostasis|blood vessel endothelial cell differentiation|vascular wound healing|ERK1 and ERK2 cascade|positive regulation of ERK1 and ERK2 cascade|cell periphery|positive regulation of cell migration involved in sprouting angiogenesis|positive regulation of mitochondrial fission|sorting endosome|regulation of hematopoietic progenitor cell differentiation|regulation of bone development|cellular response to hydrogen sulfide|negative regulation of endothelial cell apoptotic process|positive regulation of vasculogenesis	"mmu01521,mmu04010,mmu04014,mmu04015,mmu04020,mmu04151,mmu04370,mmu04510,mmu05205,mmu05418"	EGFR tyrosine kinase inhibitor resistance|MAPK signaling pathway|Ras signaling pathway|Rap1 signaling pathway|Calcium signaling pathway|PI3K-Akt signaling pathway|VEGF signaling pathway|Focal adhesion|Proteoglycans in cancer|Fluid shear stress and atherosclerosis
Klf15	1.247966988	0.319579771	0.003057784	Up	3.843174223	3.819854857	3.847750351	4.809214519	5.248904855	4.427518964	Kruppel-like factor 15	"GO:0000976,GO:0000977,GO:0000978,GO:0000981,GO:0001228,GO:0001678,GO:0003677,GO:0003700,GO:0005515,GO:0005634,GO:0005654,GO:0006357,GO:0010001,GO:0010468,GO:0014898,GO:0016607,GO:0030111,GO:0032868,GO:0043231,GO:0045893,GO:0045944,GO:0046326,GO:0046872,GO:0072112,GO:1990837,GO:2000757"	"transcription cis-regulatory region binding|RNA polymerase II transcription regulatory region sequence-specific DNA binding|RNA polymerase II cis-regulatory region sequence-specific DNA binding|DNA-binding transcription factor activity, RNA polymerase II-specific|DNA-binding transcription activator activity, RNA polymerase II-specific|cellular glucose homeostasis|DNA binding|DNA-binding transcription factor activity|protein binding|nucleus|nucleoplasm|regulation of transcription by RNA polymerase II|glial cell differentiation|regulation of gene expression|cardiac muscle hypertrophy in response to stress|nuclear speck|regulation of Wnt signaling pathway|response to insulin|intracellular membrane-bounded organelle|positive regulation of transcription, DNA-templated|positive regulation of transcription by RNA polymerase II|positive regulation of glucose import|metal ion binding|glomerular visceral epithelial cell differentiation|sequence-specific double-stranded DNA binding|negative regulation of peptidyl-lysine acetylation"		
Klf2	1.348832297	0.431710987	0.016563309	Up	3.649798648	5.915596621	5.60316381	4.786125929	7.773052843	8.110355096	Kruppel-like factor 2 (lung)	"GO:0000122,GO:0000785,GO:0000902,GO:0000978,GO:0000981,GO:0001701,GO:0003677,GO:0003700,GO:0005515,GO:0005634,GO:0006357,GO:0032715,GO:0034101,GO:0035264,GO:0036003,GO:0040029,GO:0042311,GO:0043249,GO:0045429,GO:0045893,GO:0045944,GO:0046872,GO:0048386,GO:0051247,GO:0060509,GO:0071498,GO:0071499,GO:0097533,GO:1903671,GO:1990837"	"negative regulation of transcription by RNA polymerase II|chromatin|cell morphogenesis|RNA polymerase II cis-regulatory region sequence-specific DNA binding|DNA-binding transcription factor activity, RNA polymerase II-specific|in utero embryonic development|DNA binding|DNA-binding transcription factor activity|protein binding|nucleus|regulation of transcription by RNA polymerase II|negative regulation of interleukin-6 production|erythrocyte homeostasis|multicellular organism growth|positive regulation of transcription from RNA polymerase II promoter in response to stress|regulation of gene expression, epigenetic|vasodilation|erythrocyte maturation|positive regulation of nitric oxide biosynthetic process|positive regulation of transcription, DNA-templated|positive regulation of transcription by RNA polymerase II|metal ion binding|positive regulation of retinoic acid receptor signaling pathway|positive regulation of protein metabolic process|type I pneumocyte differentiation|cellular response to fluid shear stress|cellular response to laminar fluid shear stress|cellular stress response to acid chemical|negative regulation of sprouting angiogenesis|sequence-specific double-stranded DNA binding"	"mmu04068,mmu04371,mmu05418"	FoxO signaling pathway|Apelin signaling pathway|Fluid shear stress and atherosclerosis
Lctl	3.444941008	1.784479278	0.022459492	Up	0.071699383	0.095702697	0.258140163	0.371664417	0.528443842	0.432542558	lactase-like	"GO:0002089,GO:0004553,GO:0005783,GO:0005903,GO:0005975,GO:0007601,GO:0008422,GO:0016020,GO:0016021,GO:0050896"	"lens morphogenesis in camera-type eye|hydrolase activity, hydrolyzing O-glycosyl compounds|endoplasmic reticulum|brush border|carbohydrate metabolic process|visual perception|beta-glucosidase activity|membrane|integral component of membrane|response to stimulus"		
Lim2	274.61435	8.101263205	0.004378685	Up	0	0	8.756497118	8.901852385	9.38671555	11.29011561	lens intrinsic membrane protein 2	"GO:0002088,GO:0005212,GO:0005886,GO:0005923,GO:0016020,GO:0016021,GO:0031982,GO:0043010"	lens development in camera-type eye|structural constituent of eye lens|plasma membrane|bicellular tight junction|membrane|integral component of membrane|vesicle|camera-type eye development		
Lime1	1.35900085	0.442546358	0.004251934	Up	6.256561099	6.505267489	8.516301412	7.255400724	10.63305325	11.43471963	Lck interacting transmembrane adaptor 1	"GO:0002250,GO:0002376,GO:0005515,GO:0005886,GO:0006357,GO:0014066,GO:0016020,GO:0016021,GO:0019815,GO:0019901,GO:0043122,GO:0043405,GO:0050852,GO:0050853,GO:0051279,GO:1901222"	adaptive immune response|immune system process|protein binding|plasma membrane|regulation of transcription by RNA polymerase II|regulation of phosphatidylinositol 3-kinase signaling|membrane|integral component of membrane|B cell receptor complex|protein kinase binding|regulation of I-kappaB kinase/NF-kappaB signaling|regulation of MAP kinase activity|T cell receptor signaling pathway|B cell receptor signaling pathway|regulation of release of sequestered calcium ion into cytosol|regulation of NIK/NF-kappaB signaling		
LOC118567843	0.110846456	-3.173365456	0.009385886	Down	0.218674838	0.535117321	0.095430023	0.047230565	0.048839173	0					
Med12	1.217202429	0.283569118	0.0211728	Up	2.434941144	2.506154194	2.629353019	2.862923152	3.229560394	3.188912092	mediator complex subunit 12	"GO:0000151,GO:0000978,GO:0001756,GO:0001843,GO:0003682,GO:0003712,GO:0003713,GO:0005515,GO:0005634,GO:0005654,GO:0006357,GO:0007492,GO:0007507,GO:0008013,GO:0008022,GO:0008134,GO:0014003,GO:0014044,GO:0016567,GO:0016592,GO:0019827,GO:0019904,GO:0021510,GO:0021915,GO:0036342,GO:0045893,GO:0045944,GO:0046966,GO:0048568,GO:0048702,GO:0060070,GO:0060071,GO:0060261,GO:0061630,GO:0090245,GO:1990403"	"ubiquitin ligase complex|RNA polymerase II cis-regulatory region sequence-specific DNA binding|somitogenesis|neural tube closure|chromatin binding|transcription coregulator activity|transcription coactivator activity|protein binding|nucleus|nucleoplasm|regulation of transcription by RNA polymerase II|endoderm development|heart development|beta-catenin binding|protein C-terminus binding|transcription factor binding|oligodendrocyte development|Schwann cell development|protein ubiquitination|mediator complex|stem cell population maintenance|protein domain specific binding|spinal cord development|neural tube development|post-anal tail morphogenesis|positive regulation of transcription, DNA-templated|positive regulation of transcription by RNA polymerase II|thyroid hormone receptor binding|embryonic organ development|embryonic neurocranium morphogenesis|canonical Wnt signaling pathway|Wnt signaling pathway, planar cell polarity pathway|positive regulation of transcription initiation from RNA polymerase II promoter|ubiquitin protein ligase activity|axis elongation involved in somitogenesis|embryonic brain development"	mmu04919	Thyroid hormone signaling pathway
Mgarp	14.59377305	3.867281018	0.020824522	Up	0.085464577	0	1.426605196	1.495186929	1.932638665	1.819708834	mitochondria localized glutamic acid rich protein	"GO:0005515,GO:0005739,GO:0005741,GO:0006626,GO:0008089,GO:0008090,GO:0010822,GO:0016020,GO:0016021,GO:0019896,GO:0031307,GO:0071383,GO:0071456,GO:0097211"	protein binding|mitochondrion|mitochondrial outer membrane|protein targeting to mitochondrion|anterograde axonal transport|retrograde axonal transport|positive regulation of mitochondrion organization|membrane|integral component of membrane|axonal transport of mitochondrion|integral component of mitochondrial outer membrane|cellular response to steroid hormone stimulus|cellular response to hypoxia|cellular response to gonadotropin-releasing hormone		
Mgp	1.265135352	0.339291741	0.003130873	Up	43.73673971	35.50523533	38.34098371	57.59047819	45.41370228	46.92511484	matrix Gla protein	"GO:0001503,GO:0005509,GO:0005576,GO:0005615,GO:0005783,GO:0007275,GO:0030154,GO:0030324,GO:0030500,GO:0031012,GO:0032991,GO:0048306,GO:0048754,GO:0051216,GO:0062023,GO:0065003"	ossification|calcium ion binding|extracellular region|extracellular space|endoplasmic reticulum|multicellular organism development|cell differentiation|lung development|regulation of bone mineralization|extracellular matrix|protein-containing complex|calcium-dependent protein binding|branching morphogenesis of an epithelial tube|cartilage development|collagen-containing extracellular matrix|protein-containing complex assembly		
Mip	243.7721926	7.929389755	0.000516026	Up	0.024218898	0	9.702491692	10.09830574	9.736354393	11.80879606	major intrinsic protein of lens fiber	"GO:0002088,GO:0005212,GO:0005515,GO:0005783,GO:0005886,GO:0005921,GO:0006833,GO:0007154,GO:0007601,GO:0015250,GO:0015267,GO:0015722,GO:0016020,GO:0016021,GO:0016324,GO:0030054,GO:0043231,GO:0045785,GO:0046691,GO:0050896,GO:0051289,GO:0055085,GO:1990349"	lens development in camera-type eye|structural constituent of eye lens|protein binding|endoplasmic reticulum|plasma membrane|gap junction|water transport|cell communication|visual perception|water channel activity|channel activity|canalicular bile acid transport|membrane|integral component of membrane|apical plasma membrane|cell junction|intracellular membrane-bounded organelle|positive regulation of cell adhesion|intracellular canaliculus|response to stimulus|protein homotetramerization|transmembrane transport|gap junction-mediated intercellular transport		
Mphosph9	1.290047828	0.367424554	0.012556176	Up	1.971150906	1.80884493	2.322575563	2.209589295	2.859357867	2.867927947	M-phase phosphoprotein 9	"GO:0005737,GO:0005794,GO:0005814,GO:0005856,GO:0016020"	cytoplasm|Golgi apparatus|centriole|cytoskeleton|membrane		
Mtf2	1.208317681	0.272999806	0.01610252	Up	3.953666231	4.064697103	4.445911109	4.400772133	5.36680668	5.431616636	metal response element binding transcription factor 2	"GO:0000122,GO:0000977,GO:0001222,GO:0003677,GO:0003682,GO:0005515,GO:0005634,GO:0005654,GO:0005737,GO:0005925,GO:0006325,GO:0006355,GO:0007379,GO:0019827,GO:0035064,GO:0035098,GO:0045944,GO:0046872,GO:0048863,GO:0061086,GO:0061087,GO:1990830"	"negative regulation of transcription by RNA polymerase II|RNA polymerase II transcription regulatory region sequence-specific DNA binding|transcription corepressor binding|DNA binding|chromatin binding|protein binding|nucleus|nucleoplasm|cytoplasm|focal adhesion|chromatin organization|regulation of transcription, DNA-templated|segment specification|stem cell population maintenance|methylated histone binding|ESC/E(Z) complex|positive regulation of transcription by RNA polymerase II|metal ion binding|stem cell differentiation|negative regulation of histone H3-K27 methylation|positive regulation of histone H3-K27 methylation|cellular response to leukemia inhibitory factor"		
Nat8f3	0.551090396	-0.85963911	0.039664399	Down	1.346602406	1.434107003	1.35036601	0.751868918	0.691090253	0.854053977	N-acetyltransferase 8 (GCN5-related) family member 3	"GO:0001702,GO:0003401,GO:0005615,GO:0005634,GO:0005783,GO:0005794,GO:0007162,GO:0008080,GO:0010485,GO:0016021,GO:0016573,GO:0031965"	gastrulation with mouth forming second|axis elongation|extracellular space|nucleus|endoplasmic reticulum|Golgi apparatus|negative regulation of cell adhesion|N-acetyltransferase activity|H4 histone acetyltransferase activity|integral component of membrane|histone acetylation|nuclear membrane	mmu00480	Glutathione metabolism
Nfkbia	1.367387	0.451421614	0.001688251	Up	8.728374389	9.571587981	10.56582297	10.52330784	13.92859798	15.60524213	"nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha"	"GO:0005515,GO:0005634,GO:0005737,GO:0005829,GO:0005886,GO:0006606,GO:0007249,GO:0007253,GO:0008139,GO:0010468,GO:0010745,GO:0010875,GO:0010888,GO:0019899,GO:0031072,GO:0031625,GO:0031663,GO:0032088,GO:0032270,GO:0032495,GO:0032496,GO:0032991,GO:0033209,GO:0034142,GO:0035994,GO:0042127,GO:0042802,GO:0042994,GO:0043330,GO:0044877,GO:0045638,GO:0045746,GO:0045893,GO:0045944,GO:0050729,GO:0051059,GO:0070427,GO:0070431,GO:0071216,GO:0071345,GO:0071356,GO:0071407"	"protein binding|nucleus|cytoplasm|cytosol|plasma membrane|protein import into nucleus|I-kappaB kinase/NF-kappaB signaling|cytoplasmic sequestering of NF-kappaB|nuclear localization sequence binding|regulation of gene expression|negative regulation of macrophage derived foam cell differentiation|positive regulation of cholesterol efflux|negative regulation of lipid storage|enzyme binding|heat shock protein binding|ubiquitin protein ligase binding|lipopolysaccharide-mediated signaling pathway|negative regulation of NF-kappaB transcription factor activity|positive regulation of cellular protein metabolic process|response to muramyl dipeptide|response to lipopolysaccharide|protein-containing complex|tumor necrosis factor-mediated signaling pathway|toll-like receptor 4 signaling pathway|response to muscle stretch|regulation of cell population proliferation|identical protein binding|cytoplasmic sequestering of transcription factor|response to exogenous dsRNA|protein-containing complex binding|negative regulation of myeloid cell differentiation|negative regulation of Notch signaling pathway|positive regulation of transcription, DNA-templated|positive regulation of transcription by RNA polymerase II|positive regulation of inflammatory response|NF-kappaB binding|nucleotide-binding oligomerization domain containing 1 signaling pathway|nucleotide-binding oligomerization domain containing 2 signaling pathway|cellular response to biotic stimulus|cellular response to cytokine stimulus|cellular response to tumor necrosis factor|cellular response to organic cyclic compound"	"mmu04024,mmu04062,mmu04064,mmu04210,mmu04380,mmu04620,mmu04621,mmu04622,mmu04623,mmu04625,mmu04657,mmu04658,mmu04659,mmu04660,mmu04662,mmu04668,mmu04722,mmu04920,mmu04926,mmu04931,mmu05132,mmu05134,mmu05135,mmu05140,mmu05142,mmu05145,mmu05160,mmu05161,mmu05162,mmu05163,mmu05164,mmu05166,mmu05167,mmu05168,mmu05169,mmu05170,mmu05171,mmu05200,mmu05203,mmu05215,mmu05220,mmu05222,mmu05235,mmu05417"	cAMP signaling pathway|Chemokine signaling pathway|NF-kappa B signaling pathway|Apoptosis|Osteoclast differentiation|Toll-like receptor signaling pathway|NOD-like receptor signaling pathway|RIG-I-like receptor signaling pathway|Cytosolic DNA-sensing pathway|C-type lectin receptor signaling pathway|IL-17 signaling pathway|Th1 and Th2 cell differentiation|Th17 cell differentiation|T cell receptor signaling pathway|B cell receptor signaling pathway|TNF signaling pathway|Neurotrophin signaling pathway|Adipocytokine signaling pathway|Relaxin signaling pathway|Insulin resistance|Salmonella infection|Legionellosis|Yersinia infection|Leishmaniasis|Chagas disease|Toxoplasmosis|Hepatitis C|Hepatitis B|Measles|Human cytomegalovirus infection|Influenza A|Human T-cell leukemia virus 1 infection|Kaposi sarcoma-associated herpesvirus infection|Herpes simplex virus 1 infection|Epstein-Barr virus infection|Human immunodeficiency virus 1 infection|Coronavirus disease - COVID-19|Pathways in cancer|Viral carcinogenesis|Prostate cancer|Chronic myeloid leukemia|Small cell lung cancer|PD-L1 expression and PD-1 checkpoint pathway in cancer|Lipid and atherosclerosis
Nlrc5	2.238924078	1.162805607	0.049403274	Up	0.086442272	0.053252847	0.097936101	0.187420744	0.167072445	0.169894697	"NLR family, CARD domain containing 5"	"GO:0000166,GO:0000978,GO:0002376,GO:0005524,GO:0005634,GO:0005737,GO:0005813,GO:0005829,GO:0009617,GO:0032088,GO:0035556,GO:0043549,GO:0045087,GO:0045345,GO:0045944,GO:0060335,GO:0060339,GO:0060340"	nucleotide binding|RNA polymerase II cis-regulatory region sequence-specific DNA binding|immune system process|ATP binding|nucleus|cytoplasm|centrosome|cytosol|response to bacterium|negative regulation of NF-kappaB transcription factor activity|intracellular signal transduction|regulation of kinase activity|innate immune response|positive regulation of MHC class I biosynthetic process|positive regulation of transcription by RNA polymerase II|positive regulation of interferon-gamma-mediated signaling pathway|negative regulation of type I interferon-mediated signaling pathway|positive regulation of type I interferon-mediated signaling pathway		
Nms	10.76471308	3.428237962	0.048303741	Up	0	0.105215603	0	0.255380052	0.42252471	0.167836781	neuromedin S	"GO:0001664,GO:0005576,GO:0007218,GO:0045475"	G protein-coupled receptor binding|extracellular region|neuropeptide signaling pathway|locomotor rhythm		
Npr3	1.221558188	0.288722586	0.048217799	Up	2.038947063	2.034212245	1.818187274	2.433339247	2.425603786	2.377389015	natriuretic peptide receptor 3	"GO:0001501,GO:0002158,GO:0007193,GO:0007194,GO:0007200,GO:0008217,GO:0008528,GO:0016020,GO:0016021,GO:0016941,GO:0017046,GO:0030157,GO:0031404,GO:0032991,GO:0033688,GO:0035810,GO:0042277,GO:0042562,GO:0042802,GO:0042803,GO:0048015,GO:0048662,GO:0051000,GO:0120163"	skeletal system development|osteoclast proliferation|adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway|negative regulation of adenylate cyclase activity|phospholipase C-activating G protein-coupled receptor signaling pathway|regulation of blood pressure|G protein-coupled peptide receptor activity|membrane|integral component of membrane|natriuretic peptide receptor activity|peptide hormone binding|pancreatic juice secretion|chloride ion binding|protein-containing complex|regulation of osteoblast proliferation|positive regulation of urine volume|peptide binding|hormone binding|identical protein binding|protein homodimerization activity|phosphatidylinositol-mediated signaling|negative regulation of smooth muscle cell proliferation|positive regulation of nitric-oxide synthase activity|negative regulation of cold-induced thermogenesis		
Nr1d1	1.361233899	0.444914984	4.99E-12	Up	40.2340134	36.61424824	33.89161823	53.86868378	48.07959961	49.61005933	"nuclear receptor subfamily 1, group D, member 1"	"GO:0000122,GO:0000785,GO:0000976,GO:0000977,GO:0000978,GO:0001222,GO:0001227,GO:0001678,GO:0003677,GO:0003700,GO:0004879,GO:0005515,GO:0005634,GO:0005654,GO:0005737,GO:0005978,GO:0006355,GO:0007623,GO:0008270,GO:0009755,GO:0010498,GO:0016604,GO:0019216,GO:0020037,GO:0030054,GO:0030154,GO:0030425,GO:0031648,GO:0032922,GO:0034144,GO:0042632,GO:0042749,GO:0042752,GO:0042753,GO:0042995,GO:0043025,GO:0043124,GO:0043197,GO:0043565,GO:0044321,GO:0045202,GO:0045598,GO:0045892,GO:0045893,GO:0045944,GO:0046872,GO:0048511,GO:0050728,GO:0060086,GO:0061178,GO:0061469,GO:0061889,GO:0070859,GO:0070888,GO:0071222,GO:0071347,GO:0071356,GO:0120163,GO:0150079,GO:1903979,GO:1990837,GO:2000489"	"negative regulation of transcription by RNA polymerase II|chromatin|transcription cis-regulatory region binding|RNA polymerase II transcription regulatory region sequence-specific DNA binding|RNA polymerase II cis-regulatory region sequence-specific DNA binding|transcription corepressor binding|DNA-binding transcription repressor activity, RNA polymerase II-specific|cellular glucose homeostasis|DNA binding|DNA-binding transcription factor activity|nuclear receptor activity|protein binding|nucleus|nucleoplasm|cytoplasm|glycogen biosynthetic process|regulation of transcription, DNA-templated|circadian rhythm|zinc ion binding|hormone-mediated signaling pathway|proteasomal protein catabolic process|nuclear body|regulation of lipid metabolic process|heme binding|cell junction|cell differentiation|dendrite|protein destabilization|circadian regulation of gene expression|negative regulation of toll-like receptor 4 signaling pathway|cholesterol homeostasis|regulation of circadian sleep/wake cycle|regulation of circadian rhythm|positive regulation of circadian rhythm|cell projection|neuronal cell body|negative regulation of I-kappaB kinase/NF-kappaB signaling|dendritic spine|sequence-specific DNA binding|response to leptin|synapse|regulation of fat cell differentiation|negative regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|positive regulation of transcription by RNA polymerase II|metal ion binding|rhythmic process|negative regulation of inflammatory response|circadian temperature homeostasis|regulation of insulin secretion involved in cellular response to glucose stimulus|regulation of type B pancreatic cell proliferation|negative regulation of astrocyte activation|positive regulation of bile acid biosynthetic process|E-box binding|cellular response to lipopolysaccharide|cellular response to interleukin-1|cellular response to tumor necrosis factor|negative regulation of cold-induced thermogenesis|negative regulation of neuroinflammatory response|negative regulation of microglial cell activation|sequence-specific double-stranded DNA binding|regulation of hepatic stellate cell activation"	mmu04710	Circadian rhythm
Olfml2b	1.349432235	0.432352531	0.015290065	Up	2.716844705	3.020131196	3.142296571	3.887991361	4.238183239	3.921527313	olfactomedin-like 2B	"GO:0005576,GO:0030198,GO:0031012,GO:0042802,GO:0050840"	extracellular region|extracellular matrix organization|extracellular matrix|identical protein binding|extracellular matrix binding		
Olig2	0.8259469	-0.275879062	0.009580282	Down	14.60118038	16.7359646	15.39538	13.75326244	14.08379624	11.12102104	oligodendrocyte transcription factor 2	"GO:0000122,GO:0000978,GO:0000981,GO:0003677,GO:0003700,GO:0005515,GO:0005634,GO:0005667,GO:0005737,GO:0006355,GO:0006357,GO:0007275,GO:0007399,GO:0021522,GO:0021529,GO:0021530,GO:0021778,GO:0021794,GO:0030182,GO:0042552,GO:0042802,GO:0045665,GO:0046983,GO:0048663,GO:0048709,GO:0048714,GO:0071837,GO:1990837"	"negative regulation of transcription by RNA polymerase II|RNA polymerase II cis-regulatory region sequence-specific DNA binding|DNA-binding transcription factor activity, RNA polymerase II-specific|DNA binding|DNA-binding transcription factor activity|protein binding|nucleus|transcription regulator complex|cytoplasm|regulation of transcription, DNA-templated|regulation of transcription by RNA polymerase II|multicellular organism development|nervous system development|spinal cord motor neuron differentiation|spinal cord oligodendrocyte cell differentiation|spinal cord oligodendrocyte cell fate specification|oligodendrocyte cell fate specification|thalamus development|neuron differentiation|myelination|identical protein binding|negative regulation of neuron differentiation|protein dimerization activity|neuron fate commitment|oligodendrocyte differentiation|positive regulation of oligodendrocyte differentiation|HMG box domain binding|sequence-specific double-stranded DNA binding"		
Oxt	1.883952035	0.913762235	0.028574981	Up	6.725008488	4.959374291	0.681480208	7.908648487	15.63442349	1.24844196	oxytocin	"GO:0002027,GO:0005179,GO:0005184,GO:0005185,GO:0005576,GO:0005615,GO:0005737,GO:0007204,GO:0007625,GO:0010701,GO:0014070,GO:0030141,GO:0030431,GO:0031855,GO:0032308,GO:0032570,GO:0035176,GO:0035811,GO:0035815,GO:0042711,GO:0042713,GO:0042755,GO:0042756,GO:0043195,GO:0044058,GO:0045776,GO:0045777,GO:0045778,GO:0045925,GO:0050806,GO:0051930,GO:0051965,GO:0060406,GO:0060450,GO:0060455,GO:0070474,GO:0120162"	regulation of heart rate|hormone activity|neuropeptide hormone activity|neurohypophyseal hormone activity|extracellular region|extracellular space|cytoplasm|positive regulation of cytosolic calcium ion concentration|grooming behavior|positive regulation of norepinephrine secretion|response to organic cyclic compound|secretory granule|sleep|oxytocin receptor binding|positive regulation of prostaglandin secretion|response to progesterone|social behavior|negative regulation of urine volume|positive regulation of renal sodium excretion|maternal behavior|sperm ejaculation|eating behavior|drinking behavior|terminal bouton|regulation of digestive system process|negative regulation of blood pressure|positive regulation of blood pressure|positive regulation of ossification|positive regulation of female receptivity|positive regulation of synaptic transmission|regulation of sensory perception of pain|positive regulation of synapse assembly|positive regulation of penile erection|positive regulation of hindgut contraction|negative regulation of gastric acid secretion|positive regulation of uterine smooth muscle contraction|positive regulation of cold-induced thermogenesis	"mmu04024,mmu04080,mmu04921"	cAMP signaling pathway|Neuroactive ligand-receptor interaction|Oxytocin signaling pathway
Papss2	0.812807252	-0.29901482	0.02645921	Down	5.53576261	5.528039823	5.556673471	4.501420995	4.558333379	4.536722778	3'-phosphoadenosine 5'-phosphosulfate synthase 2	"GO:0000103,GO:0000166,GO:0003824,GO:0004020,GO:0004781,GO:0005524,GO:0007596,GO:0008152,GO:0016301,GO:0016310,GO:0016740,GO:0016779,GO:0050428,GO:0060348"	sulfate assimilation|nucleotide binding|catalytic activity|adenylylsulfate kinase activity|sulfate adenylyltransferase (ATP) activity|ATP binding|blood coagulation|metabolic process|kinase activity|phosphorylation|transferase activity|nucleotidyltransferase activity|3'-phosphoadenosine 5'-phosphosulfate biosynthetic process|bone development	"mmu00230,mmu00450,mmu00920"	Purine metabolism|Selenocompound metabolism|Sulfur metabolism
Pcf11	1.218485159	0.285088679	0.025284651	Up	4.753962131	4.383605597	4.259587342	4.699792626	5.318802422	6.536840667	PCF11 cleavage and polyadenylation factor subunit	"GO:0000993,GO:0003729,GO:0005654,GO:0005737,GO:0005739,GO:0005849,GO:0006369,GO:0006378"	RNA polymerase II complex binding|mRNA binding|nucleoplasm|cytoplasm|mitochondrion|mRNA cleavage factor complex|termination of RNA polymerase II transcription|mRNA polyadenylation	mmu03015	mRNA surveillance pathway
Per1	1.57123639	0.651900248	0.000917365	Up	8.485828687	6.419424432	7.131491017	10.27489121	10.99293468	13.59395403	period circadian clock 1	"GO:0000122,GO:0000976,GO:0000978,GO:0001222,GO:0002028,GO:0005515,GO:0005634,GO:0005654,GO:0005737,GO:0005829,GO:0007623,GO:0008134,GO:0009416,GO:0010608,GO:0019900,GO:0031490,GO:0031625,GO:0032922,GO:0042634,GO:0042752,GO:0043124,GO:0043153,GO:0043966,GO:0043967,GO:0045892,GO:0045944,GO:0046329,GO:0048511,GO:0051591,GO:0070888,GO:0070932,GO:0097167,GO:1900015,GO:1900744,GO:2000323"	"negative regulation of transcription by RNA polymerase II|transcription cis-regulatory region binding|RNA polymerase II cis-regulatory region sequence-specific DNA binding|transcription corepressor binding|regulation of sodium ion transport|protein binding|nucleus|nucleoplasm|cytoplasm|cytosol|circadian rhythm|transcription factor binding|response to light stimulus|posttranscriptional regulation of gene expression|kinase binding|chromatin DNA binding|ubiquitin protein ligase binding|circadian regulation of gene expression|regulation of hair cycle|regulation of circadian rhythm|negative regulation of I-kappaB kinase/NF-kappaB signaling|entrainment of circadian clock by photoperiod|histone H3 acetylation|histone H4 acetylation|negative regulation of transcription, DNA-templated|positive regulation of transcription by RNA polymerase II|negative regulation of JNK cascade|rhythmic process|response to cAMP|E-box binding|histone H3 deacetylation|circadian regulation of translation|regulation of cytokine production involved in inflammatory response|regulation of p38MAPK cascade|negative regulation of glucocorticoid receptor signaling pathway"	"mmu04710,mmu04713"	Circadian rhythm|Circadian entrainment
Per2	1.288159479	0.365311216	0.000661347	Up	5.464394907	4.838456395	5.255141097	6.210209869	6.586826184	7.400597905	period circadian clock 2	"GO:0000122,GO:0000976,GO:0000978,GO:0001222,GO:0002931,GO:0003713,GO:0005515,GO:0005634,GO:0005654,GO:0005737,GO:0005829,GO:0005978,GO:0006094,GO:0006631,GO:0007623,GO:0008134,GO:0016922,GO:0019229,GO:0019249,GO:0019900,GO:0031397,GO:0032922,GO:0036002,GO:0042752,GO:0042754,GO:0042802,GO:0042826,GO:0043153,GO:0045892,GO:0048471,GO:0050767,GO:0050796,GO:0050872,GO:0051726,GO:0051946,GO:0060567,GO:0070063,GO:0070345,GO:0070932,GO:0097167,GO:0120162,GO:1990226,GO:2000678"	"negative regulation of transcription by RNA polymerase II|transcription cis-regulatory region binding|RNA polymerase II cis-regulatory region sequence-specific DNA binding|transcription corepressor binding|response to ischemia|transcription coactivator activity|protein binding|nucleus|nucleoplasm|cytoplasm|cytosol|glycogen biosynthetic process|gluconeogenesis|fatty acid metabolic process|circadian rhythm|transcription factor binding|nuclear receptor binding|regulation of vasoconstriction|lactate biosynthetic process|kinase binding|negative regulation of protein ubiquitination|circadian regulation of gene expression|pre-mRNA binding|regulation of circadian rhythm|negative regulation of circadian rhythm|identical protein binding|histone deacetylase binding|entrainment of circadian clock by photoperiod|negative regulation of transcription, DNA-templated|perinuclear region of cytoplasm|regulation of neurogenesis|regulation of insulin secretion|white fat cell differentiation|regulation of cell cycle|regulation of glutamate uptake involved in transmission of nerve impulse|negative regulation of DNA-templated transcription, termination|RNA polymerase binding|negative regulation of fat cell proliferation|histone H3 deacetylation|circadian regulation of translation|positive regulation of cold-induced thermogenesis|histone methyltransferase binding|negative regulation of transcription regulatory region DNA binding"	"mmu04710,mmu04713,mmu05202,mmu05221"	Circadian rhythm|Circadian entrainment|Transcriptional misregulation in cancer|Acute myeloid leukemia
Pla2g4e	1.555771245	0.637629948	0.005766591	Up	1.108249513	1.153388185	0.937355129	1.589056294	1.775513788	1.63542251	"phospholipase A2, group IVE"	"GO:0004620,GO:0004623,GO:0005509,GO:0005544,GO:0005546,GO:0005547,GO:0005737,GO:0005764,GO:0005765,GO:0005768,GO:0005829,GO:0005886,GO:0006629,GO:0009395,GO:0010314,GO:0016020,GO:0016042,GO:0016410,GO:0016740,GO:0016787,GO:0031901,GO:0032266,GO:0043325,GO:0046475,GO:0046872,GO:0047498,GO:0070273,GO:0070292,GO:0080025,GO:0102567,GO:0102568,GO:2001137"	"phospholipase activity|phospholipase A2 activity|calcium ion binding|calcium-dependent phospholipid binding|phosphatidylinositol-4,5-bisphosphate binding|phosphatidylinositol-3,4,5-trisphosphate binding|cytoplasm|lysosome|lysosomal membrane|endosome|cytosol|plasma membrane|lipid metabolic process|phospholipid catabolic process|phosphatidylinositol-5-phosphate binding|membrane|lipid catabolic process|N-acyltransferase activity|transferase activity|hydrolase activity|early endosome membrane|phosphatidylinositol-3-phosphate binding|phosphatidylinositol-3,4-bisphosphate binding|glycerophospholipid catabolic process|metal ion binding|calcium-dependent phospholipase A2 activity|phosphatidylinositol-4-phosphate binding|N-acylphosphatidylethanolamine metabolic process|phosphatidylinositol-3,5-bisphosphate binding|phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine)|phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine)|positive regulation of endocytic recycling"	"mmu00564,mmu00565,mmu00590,mmu00591,mmu00592,mmu04010,mmu04014,mmu04072,mmu04217,mmu04270,mmu04370,mmu04611,mmu04664,mmu04666,mmu04724,mmu04726,mmu04730,mmu04750,mmu04912,mmu04913,mmu04921,mmu05231"	Glycerophospholipid metabolism|Ether lipid metabolism|Arachidonic acid metabolism|Linoleic acid metabolism|alpha-Linolenic acid metabolism|MAPK signaling pathway|Ras signaling pathway|Phospholipase D signaling pathway|Necroptosis|Vascular smooth muscle contraction|VEGF signaling pathway|Platelet activation|Fc epsilon RI signaling pathway|Fc gamma R-mediated phagocytosis|Glutamatergic synapse|Serotonergic synapse|Long-term depression|Inflammatory mediator regulation of TRP channels|GnRH signaling pathway|Ovarian steroidogenesis|Oxytocin signaling pathway|Choline metabolism in cancer
Plekhf1	1.708079467	0.772375097	0.00832505	Up	1.543557137	1.496173711	1.659969023	1.738368564	3.201160953	3.416954661	"pleckstrin homology domain containing, family F (with FYVE domain) member 1"	"GO:0005634,GO:0005737,GO:0005764,GO:0005768,GO:0006915,GO:0007032,GO:0010314,GO:0010508,GO:0016050,GO:0032266,GO:0035091,GO:0046872,GO:0046902,GO:0070273,GO:0072659,GO:2001244"	nucleus|cytoplasm|lysosome|endosome|apoptotic process|endosome organization|phosphatidylinositol-5-phosphate binding|positive regulation of autophagy|vesicle organization|phosphatidylinositol-3-phosphate binding|phosphatidylinositol binding|metal ion binding|regulation of mitochondrial membrane permeability|phosphatidylinositol-4-phosphate binding|protein localization to plasma membrane|positive regulation of intrinsic apoptotic signaling pathway		
Plekho2	0.732255469	-0.449581032	0.000455563	Down	4.118290226	4.940034932	4.729599318	2.935906151	3.382337992	3.872498239	"pleckstrin homology domain containing, family O member 2"	GO:0071888	macrophage apoptotic process		
Plin4	1.546911212	0.629390393	0.011749044	Up	0.977253016	0.721705013	0.542706486	1.261243794	1.01437779	1.151242244	perilipin 4	"GO:0005737,GO:0005811,GO:0005829,GO:0005886,GO:0016020"	cytoplasm|lipid droplet|cytosol|plasma membrane|membrane	mmu03320	PPAR signaling pathway
Ppp1r3g	1.379182229	0.46381309	0.027235704	Up	1.679668412	2.027213601	2.157925988	2.425904726	2.650519824	3.05827565	"protein phosphatase 1, regulatory subunit 3G"	"GO:0000164,GO:0005737,GO:0005979,GO:0008157,GO:0019903,GO:0042593,GO:0045725,GO:2000467,GO:2001069"	protein phosphatase type 1 complex|cytoplasm|regulation of glycogen biosynthetic process|protein phosphatase 1 binding|protein phosphatase binding|glucose homeostasis|positive regulation of glycogen biosynthetic process|positive regulation of glycogen (starch) synthase activity|glycogen binding		
Pprc1	1.25437439	0.326968011	0.011567645	Up	2.956159849	2.732341475	2.95833071	3.605266446	3.581539325	3.724813704	"peroxisome proliferative activated receptor, gamma, coactivator-related 1"	"GO:0003676,GO:0003712,GO:0003723,GO:0005634,GO:0005654,GO:0008134,GO:0030374,GO:0045944,GO:0051091"	nucleic acid binding|transcription coregulator activity|RNA binding|nucleus|nucleoplasm|transcription factor binding|nuclear receptor coactivator activity|positive regulation of transcription by RNA polymerase II|positive regulation of DNA-binding transcription factor activity		
Prg4	1.34877987	0.431654909	0.041245728	Up	2.032155511	1.250026002	2.03144135	2.760410529	2.214641095	2.137363848	"proteoglycan 4 (megakaryocyte stimulating factor, articular superficial zone protein)"	"GO:0005044,GO:0005576,GO:0005615,GO:0006955,GO:0030247,GO:0032715,GO:0042127,GO:0071425"	scavenger receptor activity|extracellular region|extracellular space|immune response|polysaccharide binding|negative regulation of interleukin-6 production|regulation of cell population proliferation|hematopoietic stem cell proliferation		
Prpf39	1.216151196	0.2823226	0.022439047	Up	3.385035211	3.232820484	3.815696388	3.461112927	4.803744334	4.591117192	pre-mRNA processing factor 39	"GO:0000243,GO:0000395,GO:0005634,GO:0005685,GO:0006396,GO:0006397,GO:0008380,GO:0071004"	commitment complex|mRNA 5'-splice site recognition|nucleus|U1 snRNP|RNA processing|mRNA processing|RNA splicing|U2-type prespliceosome		
Prss12	1.259517546	0.33287122	0.017477075	Up	6.900797443	5.938688257	7.350481956	9.315445354	8.334834749	7.905088795	"protease, serine 12 neurotrypsin (motopsin)"	"GO:0004252,GO:0005044,GO:0005576,GO:0005886,GO:0006508,GO:0006887,GO:0008233,GO:0008236,GO:0016020,GO:0016787,GO:0030424,GO:0030425,GO:0031410,GO:0031638,GO:0043083,GO:0043195,GO:0045202"	serine-type endopeptidase activity|scavenger receptor activity|extracellular region|plasma membrane|proteolysis|exocytosis|peptidase activity|serine-type peptidase activity|membrane|hydrolase activity|axon|dendrite|cytoplasmic vesicle|zymogen activation|synaptic cleft|terminal bouton|synapse		
Ptp4a1	0.831977174	-0.265384148	0.005858191	Down	11.94626982	11.3606588	9.899774885	9.594162412	8.919407644	9.235823297	protein tyrosine phosphatase 4a1	"GO:0004721,GO:0004725,GO:0004727,GO:0005634,GO:0005737,GO:0005768,GO:0005783,GO:0005856,GO:0005886,GO:0007049,GO:0007275,GO:0009898,GO:0016020,GO:0016311,GO:0016787,GO:0016791,GO:0030335"	phosphoprotein phosphatase activity|protein tyrosine phosphatase activity|prenylated protein tyrosine phosphatase activity|nucleus|cytoplasm|endosome|endoplasmic reticulum|cytoskeleton|plasma membrane|cell cycle|multicellular organism development|cytoplasmic side of plasma membrane|membrane|dephosphorylation|hydrolase activity|phosphatase activity|positive regulation of cell migration		
Ptpn12	1.209643699	0.274582164	0.016198366	Up	2.48050588	2.650598107	2.862534115	3.061015557	3.109247051	3.566485659	"protein tyrosine phosphatase, non-receptor type 12"	"GO:0002102,GO:0004721,GO:0004725,GO:0004726,GO:0005515,GO:0005634,GO:0005737,GO:0005829,GO:0006470,GO:0016311,GO:0016787,GO:0016791,GO:0017124,GO:0030054,GO:0035335,GO:0042058,GO:0042995,GO:0071364"	podosome|phosphoprotein phosphatase activity|protein tyrosine phosphatase activity|non-membrane spanning protein tyrosine phosphatase activity|protein binding|nucleus|cytoplasm|cytosol|protein dephosphorylation|dephosphorylation|hydrolase activity|phosphatase activity|SH3 domain binding|cell junction|peptidyl-tyrosine dephosphorylation|regulation of epidermal growth factor receptor signaling pathway|cell projection|cellular response to epidermal growth factor stimulus		
Ret	0.798582313	-0.324486975	0.015458714	Down	2.622648368	3.350008319	3.595411585	2.312245291	2.412602569	2.944638904	ret proto-oncogene	"GO:0000165,GO:0000166,GO:0000187,GO:0001657,GO:0001755,GO:0001838,GO:0004672,GO:0004713,GO:0004714,GO:0005509,GO:0005515,GO:0005524,GO:0005768,GO:0005769,GO:0005886,GO:0005887,GO:0006468,GO:0006919,GO:0007155,GO:0007156,GO:0007158,GO:0007169,GO:0007275,GO:0007399,GO:0009653,GO:0010008,GO:0010628,GO:0010976,GO:0014042,GO:0016020,GO:0016021,GO:0016301,GO:0016310,GO:0016740,GO:0030155,GO:0030182,GO:0030335,GO:0030424,GO:0030425,GO:0033139,GO:0033141,GO:0033619,GO:0033630,GO:0033674,GO:0035799,GO:0035860,GO:0042551,GO:0043025,GO:0043235,GO:0043410,GO:0045121,GO:0045793,GO:0045893,GO:0048265,GO:0048484,GO:0050770,GO:0051897,GO:0060384,GO:0061146,GO:0071300,GO:0072300,GO:0098797,GO:2001241"	"MAPK cascade|nucleotide binding|activation of MAPK activity|ureteric bud development|neural crest cell migration|embryonic epithelial tube formation|protein kinase activity|protein tyrosine kinase activity|transmembrane receptor protein tyrosine kinase activity|calcium ion binding|protein binding|ATP binding|endosome|early endosome|plasma membrane|integral component of plasma membrane|protein phosphorylation|activation of cysteine-type endopeptidase activity involved in apoptotic process|cell adhesion|homophilic cell adhesion via plasma membrane adhesion molecules|neuron cell-cell adhesion|transmembrane receptor protein tyrosine kinase signaling pathway|multicellular organism development|nervous system development|anatomical structure morphogenesis|endosome membrane|positive regulation of gene expression|positive regulation of neuron projection development|positive regulation of neuron maturation|membrane|integral component of membrane|kinase activity|phosphorylation|transferase activity|regulation of cell adhesion|neuron differentiation|positive regulation of cell migration|axon|dendrite|regulation of peptidyl-serine phosphorylation of STAT protein|positive regulation of peptidyl-serine phosphorylation of STAT protein|membrane protein proteolysis|positive regulation of cell adhesion mediated by integrin|positive regulation of kinase activity|ureter maturation|glial cell-derived neurotrophic factor receptor signaling pathway|neuron maturation|neuronal cell body|receptor complex|positive regulation of MAPK cascade|membrane raft|positive regulation of cell size|positive regulation of transcription, DNA-templated|response to pain|enteric nervous system development|regulation of axonogenesis|positive regulation of protein kinase B signaling|innervation|Peyer's patch morphogenesis|cellular response to retinoic acid|positive regulation of metanephric glomerulus development|plasma membrane protein complex|positive regulation of extrinsic apoptotic signaling pathway in absence of ligand"	"mmu04020,mmu05200,mmu05216,mmu05223,mmu05230"	Calcium signaling pathway|Pathways in cancer|Thyroid cancer|Non-small cell lung cancer|Central carbon metabolism in cancer
Rsrp1	1.513558854	0.597944775	2.47E-07	Up	54.53657739	62.03880002	78.11604931	74.46849827	111.6401358	112.2801182	arginine/serine rich protein 1				
Sap30	1.432125254	0.518157677	0.048915832	Up	2.845833152	3.694686355	3.667562123	4.019289125	5.318123515	5.396598046	sin3 associated polypeptide	"GO:0000118,GO:0000122,GO:0003677,GO:0003712,GO:0003714,GO:0005515,GO:0005634,GO:0005654,GO:0006355,GO:0016580,GO:0035914,GO:0046872,GO:0052472"	"histone deacetylase complex|negative regulation of transcription by RNA polymerase II|DNA binding|transcription coregulator activity|transcription corepressor activity|protein binding|nucleus|nucleoplasm|regulation of transcription, DNA-templated|Sin3 complex|skeletal muscle cell differentiation|metal ion binding|modulation by host of symbiont transcription"	mmu05169	Epstein-Barr virus infection
Sctr	3.687271051	1.882553473	0.035785952	Up	0.04943933	0.037119649	0.048544643	0.228245921	0.124220875	0.157899077	secretin receptor	"GO:0002024,GO:0004888,GO:0004930,GO:0005881,GO:0005886,GO:0007165,GO:0007166,GO:0007186,GO:0007188,GO:0007420,GO:0008528,GO:0009992,GO:0015055,GO:0016020,GO:0016021,GO:0017046,GO:0031667,GO:0032098,GO:0042277,GO:0043950,GO:0048167,GO:0050996,GO:0070295"	diet induced thermogenesis|transmembrane signaling receptor activity|G protein-coupled receptor activity|cytoplasmic microtubule|plasma membrane|signal transduction|cell surface receptor signaling pathway|G protein-coupled receptor signaling pathway|adenylate cyclase-modulating G protein-coupled receptor signaling pathway|brain development|G protein-coupled peptide receptor activity|cellular water homeostasis|secretin receptor activity|membrane|integral component of membrane|peptide hormone binding|response to nutrient levels|regulation of appetite|peptide binding|positive regulation of cAMP-mediated signaling|regulation of synaptic plasticity|positive regulation of lipid catabolic process|renal water absorption	"mmu04080,mmu04972,mmu04976"	Neuroactive ligand-receptor interaction|Pancreatic secretion|Bile secretion
Sfrp5	0.66418963	-0.590332896	0.01099258	Down	3.654555278	4.711720817	3.751529992	2.502536334	3.339057117	2.299010564	secreted frizzled-related sequence protein 5	"GO:0005576,GO:0005615,GO:0007275,GO:0008285,GO:0016055,GO:0017147,GO:0030111,GO:0030154,GO:0030178,GO:0030510,GO:0035567,GO:0036342,GO:0043433,GO:0043508,GO:0048546,GO:0051898,GO:0060028,GO:0060070,GO:0090090,GO:0090175,GO:0090179,GO:2000041,GO:2000057"	extracellular region|extracellular space|multicellular organism development|negative regulation of cell population proliferation|Wnt signaling pathway|Wnt-protein binding|regulation of Wnt signaling pathway|cell differentiation|negative regulation of Wnt signaling pathway|regulation of BMP signaling pathway|non-canonical Wnt signaling pathway|post-anal tail morphogenesis|negative regulation of DNA-binding transcription factor activity|negative regulation of JUN kinase activity|digestive tract morphogenesis|negative regulation of protein kinase B signaling|convergent extension involved in axis elongation|canonical Wnt signaling pathway|negative regulation of canonical Wnt signaling pathway|regulation of establishment of planar polarity|planar cell polarity pathway involved in neural tube closure|negative regulation of planar cell polarity pathway involved in axis elongation|negative regulation of Wnt signaling pathway involved in digestive tract morphogenesis	mmu04310	Wnt signaling pathway
Sgk1	1.775668172	0.828362003	0.003710549	Up	13.63793075	15.75506228	14.21099468	16.57511122	30.80811538	34.00766881	serum/glucocorticoid regulated kinase 1	"GO:0000166,GO:0004672,GO:0004674,GO:0004712,GO:0005515,GO:0005524,GO:0005634,GO:0005737,GO:0005739,GO:0005783,GO:0005829,GO:0005886,GO:0006468,GO:0006883,GO:0006915,GO:0006974,GO:0007019,GO:0007616,GO:0008542,GO:0010765,GO:0015459,GO:0016020,GO:0016301,GO:0016310,GO:0016607,GO:0016740,GO:0018105,GO:0030307,GO:0031115,GO:0032869,GO:0032880,GO:0035556,GO:0043005,GO:0043066,GO:0043402,GO:0043423,GO:0048156,GO:0048471,GO:0048812,GO:0050775,GO:0051726,GO:0106310,GO:0106311,GO:1904045"	nucleotide binding|protein kinase activity|protein serine/threonine kinase activity|protein serine/threonine/tyrosine kinase activity|protein binding|ATP binding|nucleus|cytoplasm|mitochondrion|endoplasmic reticulum|cytosol|plasma membrane|protein phosphorylation|cellular sodium ion homeostasis|apoptotic process|cellular response to DNA damage stimulus|microtubule depolymerization|long-term memory|visual learning|positive regulation of sodium ion transport|potassium channel regulator activity|membrane|kinase activity|phosphorylation|nuclear speck|transferase activity|peptidyl-serine phosphorylation|positive regulation of cell growth|negative regulation of microtubule polymerization|cellular response to insulin stimulus|regulation of protein localization|intracellular signal transduction|neuron projection|negative regulation of apoptotic process|glucocorticoid mediated signaling pathway|3-phosphoinositide-dependent protein kinase binding|tau protein binding|perinuclear region of cytoplasm|neuron projection morphogenesis|positive regulation of dendrite morphogenesis|regulation of cell cycle|protein serine kinase activity|protein threonine kinase activity|cellular response to aldosterone	"mmu04068,mmu04150,mmu04151,mmu04960"	FoxO signaling pathway|mTOR signaling pathway|PI3K-Akt signaling pathway|Aldosterone-regulated sodium reabsorption
Sik1	1.408846738	0.494514676	0.04976331	Up	2.892086188	2.825453614	3.352956716	2.867361436	5.007848414	5.391183742	salt inducible kinase 1	"GO:0000122,GO:0000166,GO:0000287,GO:0002028,GO:0004672,GO:0004674,GO:0005515,GO:0005524,GO:0005634,GO:0005737,GO:0005829,GO:0006468,GO:0007049,GO:0007275,GO:0007346,GO:0008140,GO:0010830,GO:0010868,GO:0016301,GO:0016310,GO:0016740,GO:0019901,GO:0030154,GO:0032792,GO:0035556,GO:0042149,GO:0042826,GO:0043153,GO:0043276,GO:0045595,GO:0045721,GO:0046872,GO:0048511,GO:0055007,GO:0106310,GO:0106311"	negative regulation of transcription by RNA polymerase II|nucleotide binding|magnesium ion binding|regulation of sodium ion transport|protein kinase activity|protein serine/threonine kinase activity|protein binding|ATP binding|nucleus|cytoplasm|cytosol|protein phosphorylation|cell cycle|multicellular organism development|regulation of mitotic cell cycle|cAMP response element binding protein binding|regulation of myotube differentiation|negative regulation of triglyceride biosynthetic process|kinase activity|phosphorylation|transferase activity|protein kinase binding|cell differentiation|negative regulation of CREB transcription factor activity|intracellular signal transduction|cellular response to glucose starvation|histone deacetylase binding|entrainment of circadian clock by photoperiod|anoikis|regulation of cell differentiation|negative regulation of gluconeogenesis|metal ion binding|rhythmic process|cardiac muscle cell differentiation|protein serine kinase activity|protein threonine kinase activity	mmu04922	Glucagon signaling pathway
Sirt7	1.241399186	0.311967106	0.022056206	Up	8.101493469	9.26485273	10.13695212	10.60818691	10.96948711	12.75756993	sirtuin 7	"GO:0000122,GO:0000785,GO:0001649,GO:0003682,GO:0003714,GO:0004407,GO:0005515,GO:0005634,GO:0005654,GO:0005694,GO:0005730,GO:0005731,GO:0005737,GO:0006111,GO:0006281,GO:0006282,GO:0006325,GO:0006476,GO:0006974,GO:0007072,GO:0007129,GO:0009303,GO:0010529,GO:0010821,GO:0016570,GO:0016607,GO:0016740,GO:0019213,GO:0031397,GO:0034979,GO:0035861,GO:0036049,GO:0036055,GO:0045944,GO:0046825,GO:0046872,GO:0061697,GO:0061698,GO:0062176,GO:0070403,GO:0070932,GO:0097372,GO:0106230,GO:0106231,GO:1901836,GO:1990258,GO:2000234,GO:2001032"	negative regulation of transcription by RNA polymerase II|chromatin|osteoblast differentiation|chromatin binding|transcription corepressor activity|histone deacetylase activity|protein binding|nucleus|nucleoplasm|chromosome|nucleolus|nucleolus organizer region|cytoplasm|regulation of gluconeogenesis|DNA repair|regulation of DNA repair|chromatin organization|protein deacetylation|cellular response to DNA damage stimulus|positive regulation of transcription involved in exit from mitosis|homologous chromosome pairing at meiosis|rRNA transcription|negative regulation of transposition|regulation of mitochondrion organization|histone modification|nuclear speck|transferase activity|deacetylase activity|negative regulation of protein ubiquitination|NAD-dependent protein deacetylase activity|site of double-strand break|peptidyl-lysine desuccinylation|protein-succinyllysine desuccinylase activity|positive regulation of transcription by RNA polymerase II|regulation of protein export from nucleus|metal ion binding|protein-glutaryllysine deglutarylase activity|protein deglutarylation|R-loop disassembly|NAD+ binding|histone H3 deacetylation|NAD-dependent histone deacetylase activity (H3-K18 specific)|protein depropionylation|protein-propionyllysine depropionylase activity|regulation of transcription of nucleolar large rRNA by RNA polymerase I|histone glutamine methylation|positive regulation of rRNA processing|regulation of double-strand break repair via nonhomologous end joining	mmu00760	Nicotinate and nicotinamide metabolism
Skp2	1.547860162	0.63027514	0.034227776	Up	0.749008558	0.951694141	0.777884035	1.217978236	1.38974995	1.242093288	S-phase kinase-associated protein 2	"GO:0000082,GO:0000086,GO:0000209,GO:0005515,GO:0005634,GO:0005654,GO:0005730,GO:0005737,GO:0005829,GO:0006511,GO:0019005,GO:0031146,GO:0033148,GO:0042802,GO:0042981,GO:0043161,GO:0045087,GO:0048661,GO:0051607,GO:0051726,GO:0070936,GO:1902916"	G1/S transition of mitotic cell cycle|G2/M transition of mitotic cell cycle|protein polyubiquitination|protein binding|nucleus|nucleoplasm|nucleolus|cytoplasm|cytosol|ubiquitin-dependent protein catabolic process|SCF ubiquitin ligase complex|SCF-dependent proteasomal ubiquitin-dependent protein catabolic process|positive regulation of intracellular estrogen receptor signaling pathway|identical protein binding|regulation of apoptotic process|proteasome-mediated ubiquitin-dependent protein catabolic process|innate immune response|positive regulation of smooth muscle cell proliferation|defense response to virus|regulation of cell cycle|protein K48-linked ubiquitination|positive regulation of protein polyubiquitination	"mmu04068,mmu04110,mmu04120,mmu04150,mmu05169,mmu05200,mmu05203,mmu05222"	FoxO signaling pathway|Cell cycle|Ubiquitin mediated proteolysis|mTOR signaling pathway|Epstein-Barr virus infection|Pathways in cancer|Viral carcinogenesis|Small cell lung cancer
Sntb2	1.342768092	0.42521016	0.030855314	Up	1.846353947	1.612894266	1.997699415	2.034567713	2.422987457	2.967217713	"syntrophin, basic 2"	"GO:0003779,GO:0005198,GO:0005515,GO:0005516,GO:0005622,GO:0005654,GO:0005737,GO:0005794,GO:0005856,GO:0005874,GO:0005886,GO:0016010,GO:0016020,GO:0030054,GO:0031410,GO:0032991,GO:0045202"	actin binding|structural molecule activity|protein binding|calmodulin binding|intracellular anatomical structure|nucleoplasm|cytoplasm|Golgi apparatus|cytoskeleton|microtubule|plasma membrane|dystrophin-associated glycoprotein complex|membrane|cell junction|cytoplasmic vesicle|protein-containing complex|synapse		
Sox18	0.641387551	-0.640731742	0.005144936	Down	5.685981011	6.375194682	5.168340323	4.610595808	3.036912665	3.562790954	SRY (sex determining region Y)-box 18	"GO:0000122,GO:0000785,GO:0000976,GO:0000978,GO:0000981,GO:0001228,GO:0001525,GO:0001568,GO:0001570,GO:0001701,GO:0001942,GO:0001944,GO:0001945,GO:0001946,GO:0003677,GO:0003700,GO:0005515,GO:0005634,GO:0005667,GO:0006355,GO:0007507,GO:0009653,GO:0022405,GO:0030154,GO:0035050,GO:0043565,GO:0045892,GO:0045893,GO:0045944,GO:0048469,GO:0048866,GO:0060214,GO:0060836,GO:0060956,GO:0061028,GO:0072091,GO:1990837"	"negative regulation of transcription by RNA polymerase II|chromatin|transcription cis-regulatory region binding|RNA polymerase II cis-regulatory region sequence-specific DNA binding|DNA-binding transcription factor activity, RNA polymerase II-specific|DNA-binding transcription activator activity, RNA polymerase II-specific|angiogenesis|blood vessel development|vasculogenesis|in utero embryonic development|hair follicle development|vasculature development|lymph vessel development|lymphangiogenesis|DNA binding|DNA-binding transcription factor activity|protein binding|nucleus|transcription regulator complex|regulation of transcription, DNA-templated|heart development|anatomical structure morphogenesis|hair cycle process|cell differentiation|embryonic heart tube development|sequence-specific DNA binding|negative regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|positive regulation of transcription by RNA polymerase II|cell maturation|stem cell fate specification|endocardium formation|lymphatic endothelial cell differentiation|endocardial cell differentiation|establishment of endothelial barrier|regulation of stem cell proliferation|sequence-specific double-stranded DNA binding"		
Sp2	0.80144582	-0.319323102	0.024599583	Down	5.599767995	5.906912214	5.231243659	4.802299158	4.231775355	4.467315828	Sp2 transcription factor	"GO:0000122,GO:0000978,GO:0000981,GO:0001227,GO:0001701,GO:0003677,GO:0005634,GO:0005654,GO:0006357,GO:0035264,GO:0042826,GO:0046872,GO:0048144,GO:0048568,GO:0072359,GO:1990837"	"negative regulation of transcription by RNA polymerase II|RNA polymerase II cis-regulatory region sequence-specific DNA binding|DNA-binding transcription factor activity, RNA polymerase II-specific|DNA-binding transcription repressor activity, RNA polymerase II-specific|in utero embryonic development|DNA binding|nucleus|nucleoplasm|regulation of transcription by RNA polymerase II|multicellular organism growth|histone deacetylase binding|metal ion binding|fibroblast proliferation|embryonic organ development|circulatory system development|sequence-specific double-stranded DNA binding"		
Syt9	0.827816858	-0.272616467	0.01916779	Down	7.374189033	7.706072172	7.214266387	5.935563848	6.503545385	6.14265988	synaptotagmin IX	"GO:0000149,GO:0001786,GO:0005509,GO:0005515,GO:0005544,GO:0005546,GO:0005886,GO:0014059,GO:0016020,GO:0016021,GO:0016192,GO:0017156,GO:0017158,GO:0019905,GO:0030054,GO:0030141,GO:0030276,GO:0030285,GO:0030667,GO:0031045,GO:0031410,GO:0042802,GO:0045202,GO:0045956,GO:0046872,GO:0050796,GO:0070382,GO:0071277,GO:0098686,GO:0099502"	"SNARE binding|phosphatidylserine binding|calcium ion binding|protein binding|calcium-dependent phospholipid binding|phosphatidylinositol-4,5-bisphosphate binding|plasma membrane|regulation of dopamine secretion|membrane|integral component of membrane|vesicle-mediated transport|calcium-ion regulated exocytosis|regulation of calcium ion-dependent exocytosis|syntaxin binding|cell junction|secretory granule|clathrin binding|integral component of synaptic vesicle membrane|secretory granule membrane|dense core granule|cytoplasmic vesicle|identical protein binding|synapse|positive regulation of calcium ion-dependent exocytosis|metal ion binding|regulation of insulin secretion|exocytic vesicle|cellular response to calcium ion|hippocampal mossy fiber to CA3 synapse|calcium-dependent activation of synaptic vesicle fusion"		
Tarbp2	1.311142569	0.390824568	0.037481324	Up	2.198126755	1.922281986	2.741350018	2.836300902	3.161439165	2.985672848	"TARBP2, RISC loading complex RNA binding subunit"	"GO:0003723,GO:0003725,GO:0005515,GO:0005634,GO:0005654,GO:0005737,GO:0006417,GO:0007286,GO:0007338,GO:0016442,GO:0016604,GO:0019899,GO:0030422,GO:0030423,GO:0031047,GO:0031054,GO:0035087,GO:0035196,GO:0035197,GO:0035264,GO:0035280,GO:0042802,GO:0042803,GO:0043403,GO:0045070,GO:0045727,GO:0046782,GO:0047485,GO:0050689,GO:0051149,GO:0061351,GO:0070578,GO:0070883,GO:0090065,GO:1903798"	RNA binding|double-stranded RNA binding|protein binding|nucleus|nucleoplasm|cytoplasm|regulation of translation|spermatid development|single fertilization|RISC complex|nuclear body|enzyme binding|production of siRNA involved in RNA interference|targeting of mRNA for destruction involved in RNA interference|gene silencing by RNA|pre-miRNA processing|siRNA loading onto RISC involved in RNA interference|production of miRNAs involved in gene silencing by miRNA|siRNA binding|multicellular organism growth|miRNA loading onto RISC involved in gene silencing by miRNA|identical protein binding|protein homodimerization activity|skeletal muscle tissue regeneration|positive regulation of viral genome replication|positive regulation of translation|regulation of viral transcription|protein N-terminus binding|negative regulation of defense response to virus by host|positive regulation of muscle cell differentiation|neural precursor cell proliferation|RISC-loading complex|pre-miRNA binding|regulation of production of siRNA involved in RNA interference|regulation of production of miRNAs involved in gene silencing by miRNA		
Tcf7l2	0.759245341	-0.397361945	0.000154359	Down	7.104271891	6.784881508	5.881640774	4.92624419	5.237163164	4.91429339	"transcription factor 7 like 2, T cell specific, HMG box"	"GO:0000122,GO:0000785,GO:0000976,GO:0000978,GO:0000981,GO:0001228,GO:0001568,GO:0001678,GO:0001701,GO:0003677,GO:0003682,GO:0003700,GO:0005515,GO:0005634,GO:0005654,GO:0005667,GO:0005829,GO:0005977,GO:0006006,GO:0006111,GO:0006355,GO:0006357,GO:0008013,GO:0008134,GO:0009267,GO:0009749,GO:0009791,GO:0010867,GO:0010909,GO:0014003,GO:0016055,GO:0016922,GO:0019901,GO:0021915,GO:0021983,GO:0030282,GO:0030514,GO:0030538,GO:0031641,GO:0032024,GO:0032092,GO:0032252,GO:0032350,GO:0032993,GO:0035019,GO:0035264,GO:0040037,GO:0042475,GO:0042593,GO:0043065,GO:0043433,GO:0043565,GO:0043570,GO:0043588,GO:0044334,GO:0045295,GO:0045444,GO:0045599,GO:0045722,GO:0045892,GO:0045893,GO:0045944,GO:0046621,GO:0046827,GO:0046889,GO:0048557,GO:0048619,GO:0048625,GO:0048641,GO:0048660,GO:0048713,GO:0050679,GO:0051726,GO:0051897,GO:0060070,GO:0060325,GO:0061178,GO:0061629,GO:0070016,GO:0070369,GO:0071664,GO:0090090,GO:1901142,GO:1990907,GO:2000675,GO:2001237"	"negative regulation of transcription by RNA polymerase II|chromatin|transcription cis-regulatory region binding|RNA polymerase II cis-regulatory region sequence-specific DNA binding|DNA-binding transcription factor activity, RNA polymerase II-specific|DNA-binding transcription activator activity, RNA polymerase II-specific|blood vessel development|cellular glucose homeostasis|in utero embryonic development|DNA binding|chromatin binding|DNA-binding transcription factor activity|protein binding|nucleus|nucleoplasm|transcription regulator complex|cytosol|glycogen metabolic process|glucose metabolic process|regulation of gluconeogenesis|regulation of transcription, DNA-templated|regulation of transcription by RNA polymerase II|beta-catenin binding|transcription factor binding|cellular response to starvation|response to glucose|post-embryonic development|positive regulation of triglyceride biosynthetic process|positive regulation of heparan sulfate proteoglycan biosynthetic process|oligodendrocyte development|Wnt signaling pathway|nuclear receptor binding|protein kinase binding|neural tube development|pituitary gland development|bone mineralization|negative regulation of BMP signaling pathway|embryonic genitalia morphogenesis|regulation of myelination|positive regulation of insulin secretion|positive regulation of protein binding|secretory granule localization|regulation of hormone metabolic process|protein-DNA complex|somatic stem cell population maintenance|multicellular organism growth|negative regulation of fibroblast growth factor receptor signaling pathway|odontogenesis of dentin-containing tooth|glucose homeostasis|positive regulation of apoptotic process|negative regulation of DNA-binding transcription factor activity|sequence-specific DNA binding|maintenance of DNA repeat elements|skin development|canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition|gamma-catenin binding|fat cell differentiation|negative regulation of fat cell differentiation|positive regulation of gluconeogenesis|negative regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|positive regulation of transcription by RNA polymerase II|negative regulation of organ growth|positive regulation of protein export from nucleus|positive regulation of lipid biosynthetic process|embryonic digestive tract morphogenesis|embryonic hindgut morphogenesis|myoblast fate commitment|regulation of skeletal muscle tissue development|regulation of smooth muscle cell proliferation|regulation of oligodendrocyte differentiation|positive regulation of epithelial cell proliferation|regulation of cell cycle|positive regulation of protein kinase B signaling|canonical Wnt signaling pathway|face morphogenesis|regulation of insulin secretion involved in cellular response to glucose stimulus|RNA polymerase II-specific DNA-binding transcription factor binding|armadillo repeat domain binding|beta-catenin-TCF7L2 complex|catenin-TCF7L2 complex|negative regulation of canonical Wnt signaling pathway|insulin metabolic process|beta-catenin-TCF complex|negative regulation of type B pancreatic cell apoptotic process|negative regulation of extrinsic apoptotic signaling pathway"	"mmu04310,mmu04390,mmu04520,mmu04916,mmu04934,mmu05132,mmu05165,mmu05167,mmu05200,mmu05210,mmu05213,mmu05215,mmu05216,mmu05217,mmu05221,mmu05224,mmu05225,mmu05226,mmu05412"	Wnt signaling pathway|Hippo signaling pathway|Adherens junction|Melanogenesis|Cushing syndrome|Salmonella infection|Human papillomavirus infection|Kaposi sarcoma-associated herpesvirus infection|Pathways in cancer|Colorectal cancer|Endometrial cancer|Prostate cancer|Thyroid cancer|Basal cell carcinoma|Acute myeloid leukemia|Breast cancer|Hepatocellular carcinoma|Gastric cancer|Arrhythmogenic right ventricular cardiomyopathy
Thoc1	1.278683343	0.354659035	0.022005363	Up	7.137509793	6.168722735	6.821455436	7.538412557	9.49287948	8.940996562	THO complex 1	"GO:0000018,GO:0000346,GO:0000347,GO:0000445,GO:0000781,GO:0003677,GO:0003723,GO:0005515,GO:0005634,GO:0005737,GO:0006397,GO:0006406,GO:0006915,GO:0007165,GO:0008380,GO:0016607,GO:0031297,GO:0032784,GO:0032786,GO:0042981,GO:0046784,GO:0048297,GO:0051028,GO:2000002"	"regulation of DNA recombination|transcription export complex|THO complex|THO complex part of transcription export complex|chromosome, telomeric region|DNA binding|RNA binding|protein binding|nucleus|cytoplasm|mRNA processing|mRNA export from nucleus|apoptotic process|signal transduction|RNA splicing|nuclear speck|replication fork processing|regulation of DNA-templated transcription, elongation|positive regulation of DNA-templated transcription, elongation|regulation of apoptotic process|viral mRNA export from host cell nucleus|negative regulation of isotype switching to IgA isotypes|mRNA transport|negative regulation of DNA damage checkpoint"	"mmu03013,mmu03040"	RNA transport|Spliceosome
Tia1	1.241752057	0.312377137	0.003031387	Up	6.828466631	6.723797584	8.307840114	7.951490471	10.29429118	9.096898397	cytotoxic granule-associated RNA binding protein 1	"GO:0001818,GO:0003676,GO:0003723,GO:0005515,GO:0005634,GO:0005654,GO:0005737,GO:0005829,GO:0006915,GO:0010494,GO:0017148,GO:0035925,GO:0048024,GO:0097165,GO:1903608,GO:1904037,GO:1990904"	"negative regulation of cytokine production|nucleic acid binding|RNA binding|protein binding|nucleus|nucleoplasm|cytoplasm|cytosol|apoptotic process|cytoplasmic stress granule|negative regulation of translation|mRNA 3'-UTR AU-rich region binding|regulation of mRNA splicing, via spliceosome|nuclear stress granule|protein localization to cytoplasmic stress granule|positive regulation of epithelial cell apoptotic process|ribonucleoprotein complex"		
Tll2	0.601626232	-0.733060622	0.024214623	Down	0.339760679	0.352883413	0.300250928	0.218774066	0.179272807	0.203461107	tolloid-like 2	"GO:0004222,GO:0005509,GO:0005576,GO:0006508,GO:0007275,GO:0008233,GO:0008237,GO:0008270,GO:0016787,GO:0030154,GO:0046872,GO:0048632"	metalloendopeptidase activity|calcium ion binding|extracellular region|proteolysis|multicellular organism development|peptidase activity|metallopeptidase activity|zinc ion binding|hydrolase activity|cell differentiation|metal ion binding|negative regulation of skeletal muscle tissue growth		
Tmem40	1.762962537	0.818001818	0.032834871	Up	0.964915303	0.872480151	1.742092008	2.238700824	2.095966327	1.789398299	transmembrane protein 40	"GO:0016020,GO:0016021"	membrane|integral component of membrane		
Tnip2	1.359964862	0.443569377	0.02920763	Up	3.531869292	3.401766002	3.80949516	4.498975558	4.921118005	5.298212779	TNFAIP3 interacting protein 2	"GO:0005515,GO:0005654,GO:0005737,GO:0005829,GO:0006915,GO:0006954,GO:0007249,GO:0019901,GO:0023035,GO:0031593,GO:0034134,GO:0034138,GO:0034162,GO:0043032,GO:0043123,GO:0045944,GO:0046872,GO:0050821,GO:0050871,GO:0070498,GO:0070530,GO:0071222,GO:2000352"	protein binding|nucleoplasm|cytoplasm|cytosol|apoptotic process|inflammatory response|I-kappaB kinase/NF-kappaB signaling|protein kinase binding|CD40 signaling pathway|polyubiquitin modification-dependent protein binding|toll-like receptor 2 signaling pathway|toll-like receptor 3 signaling pathway|toll-like receptor 9 signaling pathway|positive regulation of macrophage activation|positive regulation of I-kappaB kinase/NF-kappaB signaling|positive regulation of transcription by RNA polymerase II|metal ion binding|protein stabilization|positive regulation of B cell activation|interleukin-1-mediated signaling pathway|K63-linked polyubiquitin modification-dependent protein binding|cellular response to lipopolysaccharide|negative regulation of endothelial cell apoptotic process		
Tnxb	1.476368563	0.562052923	0.023288294	Up	0.292089919	0.304102459	0.409173798	0.401234261	0.497096865	0.597040177	tenascin XB	"GO:0005201,GO:0005518,GO:0005576,GO:0005615,GO:0006629,GO:0006631,GO:0006641,GO:0006644,GO:0007160,GO:0008201,GO:0030198,GO:0030199,GO:0031012,GO:0032963,GO:0043506,GO:0045785,GO:0048251,GO:0062023,GO:0098609,GO:0098633"	extracellular matrix structural constituent|collagen binding|extracellular region|extracellular space|lipid metabolic process|fatty acid metabolic process|triglyceride metabolic process|phospholipid metabolic process|cell-matrix adhesion|heparin binding|extracellular matrix organization|collagen fibril organization|extracellular matrix|collagen metabolic process|regulation of JUN kinase activity|positive regulation of cell adhesion|elastic fiber assembly|collagen-containing extracellular matrix|cell-cell adhesion|collagen fibril binding	"mmu04151,mmu04510,mmu04512,mmu05165,mmu05206"	PI3K-Akt signaling pathway|Focal adhesion|ECM-receptor interaction|Human papillomavirus infection|MicroRNAs in cancer
Trib1	1.256648298	0.329580935	0.025722868	Up	3.35794484	4.054825343	5.247258683	3.466888869	6.224447011	6.607235768	tribbles pseudokinase 1	"GO:0004672,GO:0004860,GO:0005524,GO:0005634,GO:0005737,GO:0006468,GO:0006469,GO:0007254,GO:0008134,GO:0014912,GO:0031434,GO:0031625,GO:0031665,GO:0032436,GO:0032496,GO:0043405,GO:0043433,GO:0045645,GO:0045651,GO:0045659,GO:0048662,GO:0051443,GO:0055106"	protein kinase activity|protein kinase inhibitor activity|ATP binding|nucleus|cytoplasm|protein phosphorylation|negative regulation of protein kinase activity|JNK cascade|transcription factor binding|negative regulation of smooth muscle cell migration|mitogen-activated protein kinase kinase binding|ubiquitin protein ligase binding|negative regulation of lipopolysaccharide-mediated signaling pathway|positive regulation of proteasomal ubiquitin-dependent protein catabolic process|response to lipopolysaccharide|regulation of MAP kinase activity|negative regulation of DNA-binding transcription factor activity|positive regulation of eosinophil differentiation|positive regulation of macrophage differentiation|negative regulation of neutrophil differentiation|negative regulation of smooth muscle cell proliferation|positive regulation of ubiquitin-protein transferase activity|ubiquitin-protein transferase regulator activity		
Tsc22d3	1.200976544	0.264207975	0.000433672	Up	15.98821642	18.49701763	18.25778805	18.36370455	21.96193067	23.6102601	"TSC22 domain family, member 3"	"GO:0000122,GO:0005515,GO:0005634,GO:0005737,GO:0006357,GO:0006970,GO:0043426,GO:0048642,GO:0070236"	negative regulation of transcription by RNA polymerase II|protein binding|nucleus|cytoplasm|regulation of transcription by RNA polymerase II|response to osmotic stress|MRF binding|negative regulation of skeletal muscle tissue development|negative regulation of activation-induced cell death of T cells		
Tspoap1	1.273623168	0.348938485	1.80E-07	Up	10.42327564	10.43943851	12.14766757	12.11901307	14.9940669	15.30708743	TSPO associated protein 1	"GO:0005737,GO:0005739,GO:0007274,GO:0030156,GO:0044305,GO:0098978,GO:0099626"	cytoplasm|mitochondrion|neuromuscular synaptic transmission|benzodiazepine receptor binding|calyx of Held|glutamatergic synapse|voltage-gated calcium channel activity involved in regulation of presynaptic cytosolic calcium levels		
Ubap1l	1.610612714	0.687609627	0.032615289	Up	0.150651784	0.301629837	0.306052735	0.252454505	0.496000238	0.475620421	ubiquitin-associated protein 1-like	"GO:0000813,GO:0043130,GO:0043162"	ESCRT I complex|ubiquitin binding|ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway		
Vav3	0.810205294	-0.303640582	0.048072241	Down	3.150372807	2.929904464	3.513447682	2.334268085	2.755802223	2.732792309	vav 3 oncogene	"GO:0001525,GO:0001772,GO:0005085,GO:0005154,GO:0005515,GO:0005737,GO:0005886,GO:0006906,GO:0006974,GO:0007229,GO:0007264,GO:0016477,GO:0030031,GO:0030032,GO:0030593,GO:0030890,GO:0035556,GO:0042493,GO:0043087,GO:0043552,GO:0045785,GO:0046872,GO:0050853"	angiogenesis|immunological synapse|guanyl-nucleotide exchange factor activity|epidermal growth factor receptor binding|protein binding|cytoplasm|plasma membrane|vesicle fusion|cellular response to DNA damage stimulus|integrin-mediated signaling pathway|small GTPase mediated signal transduction|cell migration|cell projection assembly|lamellipodium assembly|neutrophil chemotaxis|positive regulation of B cell proliferation|intracellular signal transduction|response to drug|regulation of GTPase activity|positive regulation of phosphatidylinositol 3-kinase activity|positive regulation of cell adhesion|metal ion binding|B cell receptor signaling pathway	"mmu04015,mmu04024,mmu04062,mmu04510,mmu04650,mmu04660,mmu04662,mmu04664,mmu04666,mmu04670,mmu04810,mmu05135,mmu05205,mmu05417"	Rap1 signaling pathway|cAMP signaling pathway|Chemokine signaling pathway|Focal adhesion|Natural killer cell mediated cytotoxicity|T cell receptor signaling pathway|B cell receptor signaling pathway|Fc epsilon RI signaling pathway|Fc gamma R-mediated phagocytosis|Leukocyte transendothelial migration|Regulation of actin cytoskeleton|Yersinia infection|Proteoglycans in cancer|Lipid and atherosclerosis
Vipr1	1.307559624	0.386876734	0.006740351	Up	2.923010752	3.06602995	3.144463119	3.686999284	4.168989598	4.175804264	vasoactive intestinal peptide receptor 1	"GO:0004888,GO:0004930,GO:0004999,GO:0005886,GO:0007165,GO:0007166,GO:0007186,GO:0007187,GO:0007188,GO:0008528,GO:0016020,GO:0016021,GO:0017046,GO:0043235"	"transmembrane signaling receptor activity|G protein-coupled receptor activity|vasoactive intestinal polypeptide receptor activity|plasma membrane|signal transduction|cell surface receptor signaling pathway|G protein-coupled receptor signaling pathway|G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger|adenylate cyclase-modulating G protein-coupled receptor signaling pathway|G protein-coupled peptide receptor activity|membrane|integral component of membrane|peptide hormone binding|receptor complex"	mmu04080	Neuroactive ligand-receptor interaction
Xdh	1.570819822	0.651517708	0.007093075	Up	1.037475876	0.970120238	1.0075065	1.473754333	1.501031853	1.8084589	xanthine dehydrogenase	"GO:0000255,GO:0001933,GO:0001937,GO:0004854,GO:0004855,GO:0005506,GO:0005515,GO:0005576,GO:0005615,GO:0005737,GO:0005777,GO:0005829,GO:0006147,GO:0006148,GO:0006149,GO:0006154,GO:0006157,GO:0006161,GO:0006196,GO:0006204,GO:0006919,GO:0007595,GO:0009055,GO:0009114,GO:0009115,GO:0010044,GO:0010629,GO:0016226,GO:0016491,GO:0016529,GO:0019428,GO:0030151,GO:0030856,GO:0042802,GO:0042803,GO:0043546,GO:0045602,GO:0046038,GO:0046055,GO:0046059,GO:0046872,GO:0050421,GO:0050660,GO:0051536,GO:0051537,GO:0051898,GO:0070674,GO:0070675,GO:0071949,GO:1900745,GO:1900747,GO:2000379,GO:2001213"	"allantoin metabolic process|negative regulation of protein phosphorylation|negative regulation of endothelial cell proliferation|xanthine dehydrogenase activity|xanthine oxidase activity|iron ion binding|protein binding|extracellular region|extracellular space|cytoplasm|peroxisome|cytosol|guanine catabolic process|inosine catabolic process|deoxyinosine catabolic process|adenosine catabolic process|deoxyadenosine catabolic process|deoxyguanosine catabolic process|AMP catabolic process|IMP catabolic process|activation of cysteine-type endopeptidase activity involved in apoptotic process|lactation|electron transfer activity|hypoxanthine catabolic process|xanthine catabolic process|response to aluminum ion|negative regulation of gene expression|iron-sulfur cluster assembly|oxidoreductase activity|sarcoplasmic reticulum|allantoin biosynthetic process|molybdenum ion binding|regulation of epithelial cell differentiation|identical protein binding|protein homodimerization activity|molybdopterin cofactor binding|negative regulation of endothelial cell differentiation|GMP catabolic process|dGMP catabolic process|dAMP catabolic process|metal ion binding|nitrite reductase (NO-forming) activity|flavin adenine dinucleotide binding|iron-sulfur cluster binding|2 iron, 2 sulfur cluster binding|negative regulation of protein kinase B signaling|hypoxanthine dehydrogenase activity|hypoxanthine oxidase activity|FAD binding|positive regulation of p38MAPK cascade|negative regulation of vascular endothelial growth factor signaling pathway|positive regulation of reactive oxygen species metabolic process|negative regulation of vasculogenesis"	"mmu00230,mmu00232,mmu00983,mmu04146"	Purine metabolism|Caffeine metabolism|Drug metabolism - other enzymes|Peroxisome
Xlr3b	2.212690946	1.145801959	0.022110312	Up	0.469673636	1.234228339	0.461174106	1.711844411	0.973581107	1.812549823	X-linked lymphocyte-regulated 3B	"GO:0000795,GO:0007286,GO:0051321,GO:0051965,GO:0061003"	synaptonemal complex|spermatid development|meiotic cell cycle|positive regulation of synapse assembly|positive regulation of dendritic spine morphogenesis		
Zbed6	1.279064481	0.355088996	0.042058226	Up	2.836614887	2.187610366	3.332022062	2.716158374	3.864556819	4.205428161	"zinc finger, BED type containing 6"	"GO:0000122,GO:0000976,GO:0001835,GO:0003309,GO:0005634,GO:0005730,GO:0005737,GO:0006357,GO:0045787,GO:0045892,GO:0051148,GO:0060548,GO:0061178"	"negative regulation of transcription by RNA polymerase II|transcription cis-regulatory region binding|blastocyst hatching|type B pancreatic cell differentiation|nucleus|nucleolus|cytoplasm|regulation of transcription by RNA polymerase II|positive regulation of cell cycle|negative regulation of transcription, DNA-templated|negative regulation of muscle cell differentiation|negative regulation of cell death|regulation of insulin secretion involved in cellular response to glucose stimulus"		
Zbtb16	1.263247721	0.337137577	0.002161329	Up	3.758763571	3.33903338	3.53328758	4.563471191	3.983986574	5.005380851	zinc finger and BTB domain containing 16	"GO:0000122,GO:0000978,GO:0000981,GO:0001222,GO:0001227,GO:0001501,GO:0001823,GO:0003677,GO:0003690,GO:0003700,GO:0005515,GO:0005634,GO:0005829,GO:0005886,GO:0006355,GO:0006357,GO:0007417,GO:0008022,GO:0008285,GO:0009880,GO:0009952,GO:0016604,GO:0016605,GO:0016607,GO:0017053,GO:0019904,GO:0030097,GO:0030326,GO:0032332,GO:0032991,GO:0034504,GO:0035116,GO:0035136,GO:0035137,GO:0042733,GO:0042802,GO:0042803,GO:0043065,GO:0045600,GO:0045638,GO:0045778,GO:0045892,GO:0045893,GO:0048133,GO:0051138,GO:0051216,GO:0061036"	"negative regulation of transcription by RNA polymerase II|RNA polymerase II cis-regulatory region sequence-specific DNA binding|DNA-binding transcription factor activity, RNA polymerase II-specific|transcription corepressor binding|DNA-binding transcription repressor activity, RNA polymerase II-specific|skeletal system development|mesonephros development|DNA binding|double-stranded DNA binding|DNA-binding transcription factor activity|protein binding|nucleus|cytosol|plasma membrane|regulation of transcription, DNA-templated|regulation of transcription by RNA polymerase II|central nervous system development|protein C-terminus binding|negative regulation of cell population proliferation|embryonic pattern specification|anterior/posterior pattern specification|nuclear body|PML body|nuclear speck|transcription repressor complex|protein domain specific binding|hemopoiesis|embryonic limb morphogenesis|positive regulation of chondrocyte differentiation|protein-containing complex|protein localization to nucleus|embryonic hindlimb morphogenesis|forelimb morphogenesis|hindlimb morphogenesis|embryonic digit morphogenesis|identical protein binding|protein homodimerization activity|positive regulation of apoptotic process|positive regulation of fat cell differentiation|negative regulation of myeloid cell differentiation|positive regulation of ossification|negative regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|male germ-line stem cell asymmetric division|positive regulation of NK T cell differentiation|cartilage development|positive regulation of cartilage development"	"mmu05200,mmu05202,mmu05221"	Pathways in cancer|Transcriptional misregulation in cancer|Acute myeloid leukemia
Zfp189	1.481853613	0.567402936	0.001993574	Up	2.79844486	2.563441335	3.466182016	3.839864625	4.264766972	5.043254067	zinc finger protein 189	"GO:0000978,GO:0000981,GO:0005634,GO:0006357"	"RNA polymerase II cis-regulatory region sequence-specific DNA binding|DNA-binding transcription factor activity, RNA polymerase II-specific|nucleus|regulation of transcription by RNA polymerase II"	mmu05168	Herpes simplex virus 1 infection
Zfp276	1.275037955	0.350540193	0.035636259	Up	3.094320422	3.995812458	4.314778968	4.057422798	5.060498155	5.496844449	zinc finger protein (C2H2 type) 276	"GO:0000775,GO:0000776,GO:0003677,GO:0005634,GO:0005694,GO:0006357,GO:0008270,GO:0043035,GO:0046872,GO:1990837"	"chromosome, centromeric region|kinetochore|DNA binding|nucleus|chromosome|regulation of transcription by RNA polymerase II|zinc ion binding|chromatin insulator sequence binding|metal ion binding|sequence-specific double-stranded DNA binding"		
Zfp40	1.329068813	0.410415803	0.009603345	Up	1.033710924	1.000479071	1.183469624	1.254831458	1.616573029	1.442962039	zinc finger protein 40	"GO:0000978,GO:0001228,GO:0005634,GO:0006357"	"RNA polymerase II cis-regulatory region sequence-specific DNA binding|DNA-binding transcription activator activity, RNA polymerase II-specific|nucleus|regulation of transcription by RNA polymerase II"	mmu05168	Herpes simplex virus 1 infection
Zfp536	0.816103952	-0.293175166	0.035908766	Down	1.036154003	1.008395934	0.970191785	0.845848237	0.727269764	0.911135141	zinc finger protein 536	"GO:0000122,GO:0000978,GO:0000981,GO:0001227,GO:0003677,GO:0005634,GO:0006355,GO:0044323,GO:0045665,GO:0046872,GO:0048387"	"negative regulation of transcription by RNA polymerase II|RNA polymerase II cis-regulatory region sequence-specific DNA binding|DNA-binding transcription factor activity, RNA polymerase II-specific|DNA-binding transcription repressor activity, RNA polymerase II-specific|DNA binding|nucleus|regulation of transcription, DNA-templated|retinoic acid-responsive element binding|negative regulation of neuron differentiation|metal ion binding|negative regulation of retinoic acid receptor signaling pathway"		
Zfp568	1.664225306	0.734850761	0.012108745	Up	0.555695628	0.32510885	0.474777129	0.680385153	0.638279542	0.93732855	zinc finger protein 568	"GO:0000122,GO:0000976,GO:0000978,GO:0000981,GO:0001222,GO:0001701,GO:0003677,GO:0005515,GO:0005634,GO:0006355,GO:0006357,GO:0007275,GO:0010646,GO:0022007,GO:0045892,GO:0046872,GO:0060028,GO:0060669"	"negative regulation of transcription by RNA polymerase II|transcription cis-regulatory region binding|RNA polymerase II cis-regulatory region sequence-specific DNA binding|DNA-binding transcription factor activity, RNA polymerase II-specific|transcription corepressor binding|in utero embryonic development|DNA binding|protein binding|nucleus|regulation of transcription, DNA-templated|regulation of transcription by RNA polymerase II|multicellular organism development|regulation of cell communication|convergent extension involved in neural plate elongation|negative regulation of transcription, DNA-templated|metal ion binding|convergent extension involved in axis elongation|embryonic placenta morphogenesis"	mmu05168	Herpes simplex virus 1 infection
Zkscan2	1.252038929	0.32427942	0.022984629	Up	0.934485163	1.063370777	1.181624191	1.097750721	1.560815567	1.367025883	zinc finger with KRAB and SCAN domains 2	"GO:0000978,GO:0000981,GO:0006357"	"RNA polymerase II cis-regulatory region sequence-specific DNA binding|DNA-binding transcription factor activity, RNA polymerase II-specific|regulation of transcription by RNA polymerase II"