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["PAM16"]
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["MET"]
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["ENSG00000199633"]
["ENSG00000228201"]
["ENSG00000260470"]
["ENSG00000260597"]
["ENSG00000262528"]
["ENSG00000270175"]
["ENSG00000273049"]
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["ENSG00000228779"]
["ENSG00000229021"]
["ENSG00000230051"]
["ENSG00000232034"]
["ENSG00000233776"]
["ENSG00000257808"]
["ENSG00000258344"]
["ENSG00000260022"]
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["ENSG00000259562"]
["ENSG00000287495"]
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["lnc-C2orf69-1"]
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["DOCK8"]
["DRD3"]
["FGF3"]
["FOXP2"]
["NUP62"]
["PAX1"]
["SLC16A2"]
["WNT11"]
["ABCD4"]
["C5AR1"]
["CLN3"]
["CLOCK"]
["CPM"]
["HCRTR1"]
["LOXL4"]
["NANS"]
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["RSPO1"]
["SF3B4"]
["SKIV2L"]
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["TRHR"]
["ARHGDIB"]
["CEBPE"]
["CRHR2"]
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["FAF1"]
["FGF12"]
["FGF4"]
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["SOD3"]
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["DGCR8"]
["FCGR1A"]
["FGF18"]
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["NUP133"]
["NUP153"]
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["VIL1"]
["WNT8A"]
["ALX4"]
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["FREM2"]
["NUP160"]
["RAB8B"]
["ALX1"]
["ANKK1"]
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["CD200R1"]
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["ETNK1"]
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["IPO11"]
["MBNL1"]
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["SLCO1C1"]
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["TBX22"]
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["TTC37"]
["VPS45"]
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["CLN6"]
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["CXXC4"]
["FCRL3"]
["MEMO1"]
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["MYO5C"]
["NECTIN1"]
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["LHX9"]
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["NUP54"]
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["PI15"]
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["RUFY2"]
["TBX10"]
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["ASPG"]
["CST9L"]
["DCTPP1"]
["DHRS11"]
["GRHL1"]
["HCST"]
["MRAP"]
["ZNF189"]
["ALX3"]
["CLEC5A"]
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["MAGEB2"]
["MYO7B"]
["NOL11"]
["NUFIP1"]
["WDR43"]
["MYO19"]
["NDC1"]
["NHLH1"]
["TMEM119"]
["ZMYM5"]
["ZNF236"]
["ZNF431"]
["ZSCAN5A"]
["CYLC1"]
["KDF1"]
["MAMDC4"]
["TBC1D30"]
["TREML4"]
["CEP43"]
["PKD1L3"]
["RGPD2"]
["ZNF714"]
["ZNF787"]
["TMEM185A"]
["MAGEB16"]
["TRMO"]
["ZSCAN5B"]
["RTL3"]
["CSKMT"]
["SOX2-OT"]
["MIR135A1"]
["MRGPRG-AS1"]
["FMR1-AS1"]
["MIR449C"]
["MIR1304"]
["SNHG22"]
["HCP5B"]
["ENSG00000237501"]
["OFC1"]
["GRDX"]
["MAP3K7"]
["STAT6"]
["AIFM1"]
["FANCC"]
["ABCC6"]
["FANCD2"]
["SLC34A2"]
["AGXT"]
["AKR1D1"]
["DHCR24"]
["DLL4"]
["FANCL"]
["GATM"]
["CDKN2C"]
["SLC29A3"]
["ATP6V0A4"]
["BAAT"]
["EBP"]
["MAD2L2"]
["PALB2"]
["PTDSS1"]
["SEMA3E"]
["AP2S1"]
["FANCG"]
["FANCM"]
["HHAT"]
["LEMD3"]
["LPIN2"]
["POLR1B"]
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["UBE2T"]
["XRCC2"]
["CEP164"]
["FANCE"]
["FANCF"]
["FANCI"]
["NAB2"]
["SIK3"]
["TBCE"]
["BMS1"]
["LEMD2"]
["LRRK1"]
["NPHP3"]
["RFWD3"]
["DDRGK1"]
["WDR72"]
["FAM111A"]
["CCDC141"]
["TMEM53"]
["ARL6IP6"]
["NDUFAF6"]
["RTL1"]
["RETREG1"]
["CREBBP"]
["BCHE"]
["ABCG2"]
["ACAT1"]
["GCK"]
["MME"]
["RARB"]
["ECE1"]
["EDNRB"]
["FGG"]
["MMP19"]
["PLA2G4A"]
["TBXA2R"]
["TNNI3"]
["BACE1"]
["CACNA1A"]
["CHAT"]
["CPT1A"]
["CYP2D6"]
["DGAT1"]
["FGA"]
["IDE"]
["LCAT"]
["MAPK7"]
["P2RY12"]
["PROS1"]
["ACACB"]
["ADRA1A"]
["CFB"]
["DLST"]
["HMGCS2"]
["KAT2A"]
["NCSTN"]
["OGG1"]
["PPP1CB"]
["PTGIS"]
["RORB"]
["RXRB"]
["ABL2"]
["FRK"]
["HPD"]
["HSPA1A"]
["KLF4"]
["KLF5"]
["LRAT"]
["MSR1"]
["PRKAB2"]
["SOX5"]
["TNKS"]
["A2M"]
["ADAMTS5"]
["APOA5"]
["BLMH"]
["C4B"]
["CPT1B"]
["CYP26A1"]
["GPNMB"]
["KLK4"]
["LTB4R"]
["MMP16"]
["PCSK2"]
["RNASEL"]
["AGTR2"]
["ALOX5AP"]
["EGR2"]
["ELAC2"]
["H6PD"]
["KDM6B"]
["LRPAP1"]
["NRF1"]
["OPCML"]
["PER2"]
["PSENEN"]
["S1PR1"]
["TRAF2"]
["USF1"]
["ADH1A"]
["CABIN1"]
["FGF13"]
["GPAM"]
["HOXD13"]
["IGSF3"]
["ITPKC"]
["MLYCD"]
["PEA15"]
["PLA2G2D"]
["PRKAG3"]
["PTBP1"]
["S100A6"]
["SRF"]
["TFB1M"]
["TLE4"]
["TNFAIP1"]
["TNFRSF6B"]
["TRAF1"]
["TRIB3"]
["TRIM25"]
["TTPA"]
["VAMP2"]
["APH1B"]
["BACE2"]
["CAPN10"]
["CREM"]
["DYNLL1"]
["GTF2B"]
["HMGCS1"]
["INSIG1"]
["ME1"]
["PARD6A"]
["PIP4K2B"]
["SCAP"]
["TRAF5"]
["UBQLN1"]
["VTI1B"]
["CLEC3B"]
["CTNNA3"]
["EGR3"]
["LCN1"]
["SENP3"]
["TFCP2"]
["ABCA8"]
["APBB2"]
["CEBPD"]
["CLEC12A"]
["NFRKB"]
["RGN"]
["TNFAIP2"]
["VGF"]
["BRD8"]
["CLEC11A"]
["IL20"]
["REG3A"]
["STOM"]
["TFB2M"]
["TMBIM6"]
["VTI1A"]
["CCNI"]
["HINT2"]
["PHF12"]
["UCN"]
["ADGRA2"]
["NIPSNAP3B"]
["ANKMY1"]
["PHACTR2"]
["S100G"]
["SAA2"]
["CFAP20"]
["CCN4"]
["KMT5C"]
["IGF2-AS"]
["MIR143"]
["TNXA"]
["MIR138-2"]
["MIR378A"]
["MIR9-1HG"]
["MIR96"]
["DGCR5"]
["HOTAIRM1"]
["MIR103A1"]
["MIR488"]
["IL6-AS1"]
["MMADHC-DT"]
["RPL28P1"]
["LOC109363676"]
["LOC109433677"]
["AKT2"]
["IKBKB"]
["ITK"]
["NTRK3"]
["ADA"]
["DNMT1"]
["TLR3"]
["CPT2"]
["DLD"]
["MAPK10"]
["PCNA"]
["PRKAG2"]
["AHCY"]
["EEF2"]
["NRXN1"]
["RAB27A"]
["ARSA"]
["CAPN3"]
["CPS1"]
["CTSC"]
["GABRA1"]
["GABRA5"]
["GDNF"]
["PCYT1A"]
["PTK6"]
["RRM1"]
["SIRT2"]
["SLC29A1"]
["SLCO1B1"]
["TLR8"]
["TUBB1"]
["XIAP"]
["ABCC3"]
["AK1"]
["AKR1B1"]
["APRT"]
["ATRX"]
["BCKDK"]
["BUB3"]
["CAPN2"]
["CD55"]
["CD79B"]
["CR1"]
["CR2"]
["CRKL"]
["DCTN1"]
["DRD4"]
["ECHS1"]
["FTL"]
["GFAP"]
["HYAL1"]
["LIMK2"]
["MAG"]
["MAN1B1"]
["MAX"]
["OGDH"]
["PAX2"]
["PDHX"]
["PDP1"]
["PIN1"]
["PSAT1"]
["RAB7A"]
["RAG1"]
["SGPL1"]
["SLC18A2"]
["TPH2"]
["UBE3A"]
["YWHAB"]
["ACADM"]
["ACADVL"]
["ADARB1"]
["AMT"]
["ANXA5"]
["ARRB2"]
["BLNK"]
["BMX"]
["CD59"]
["CFL1"]
["CHRNA7"]
["CTPS1"]
["CTSZ"]
["CYP2E1"]
["DDX3X"]
["DOT1L"]
["EHMT1"]
["EHMT2"]
["EIF4A1"]
["EYA1"]
["FDXR"]
["HMGCL"]
["IGFBP7"]
["LAMA4"]
["MPZ"]
["NEFH"]
["NTN1"]
["PARK7"]
["PITX1"]
["PML"]
["POLR2A"]
["PON3"]
["PSPH"]
["SAG"]
["SH2D1A"]
["SPTA1"]
["SSTR3"]
["TEC"]
["TLL1"]
["TXK"]
["UGDH"]
["XPA"]
["YWHAQ"]
["ALS2"]
["APOL1"]
["BCKDHA"]
["COL4A4"]
["COL6A3"]
["DDB1"]
["ENPP2"]
["FUS"]
["FZD9"]
["GAL"]
["GALM"]
["HNMT"]
["IL1RAP"]
["IREB2"]
["KCNH5"]
["MMAB"]
["NEK1"]
["NKX2-5"]
["PARP2"]
["PLN"]
["SLC6A19"]
["SMARCC2"]
["STEAP3"]
["TCF3"]
["TRPM8"]
["VAPB"]
["ALAS1"]
["APEX1"]
["B3GAT1"]
["BSG"]
["CANX"]
["CUL5"]
["FBLN2"]
["FCGRT"]
["GCSH"]
["GYS2"]
["HBA1"]
["IGLL1"]
["IL12RB2"]
["LAMP2"]
["LOXL1"]
["MANBA"]
["MGAM"]
["MIPEP"]
["MTHFS"]
["NCK1"]
["NDUFS4"]
["NID1"]
["NR2C2"]
["NSDHL"]
["PANK2"]
["PHKG1"]
["PLCE1"]
["PNKD"]
["POLR1A"]
["POLRMT"]
["PPOX"]
["PRPF31"]
["RAD17"]
["RARS2"]
["SALL4"]
["SNRNP200"]
["STK38L"]
["TACC3"]
["THBS4"]
["AHI1"]
["ALG8"]
["ARHGEF6"]
["ATXN2"]
["BBS4"]
["BMI1"]
["CAV3"]
["CCBE1"]
["COL9A3"]
["ERF"]
["ESD"]
["EXOSC3"]
["FXYD2"]
["GALE"]
["GMPR"]
["GTF2H1"]
["HIBCH"]
["HLCS"]
["IQGAP1"]
["MEOX1"]
["MNX1"]
["MR1"]
["MUS81"]
["NCK2"]
["NSUN2"]
["PGF"]
["PHKA1"]
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["RAB10"]
["RAB23"]
["RAB2A"]
["RAB3A"]
["RABGEF1"]
["RGMA"]
["RNF13"]
["RNMT"]
["RPS12"]
["SLC35A3"]
["SLC39A4"]
["SLC46A1"]
["SMARCA5"]
["TMLHE"]
["TRIM27"]
["UAP1"]
["UGP2"]
["UNC119"]
["ALG11"]
["ALG6"]
["ARL1"]
["CACNG3"]
["CHST14"]
["CLP1"]
["COG4"]
["CSGALNACT1"]
["ELP3"]
["FCN1"]
["FMO4"]
["FSCN2"]
["GALK2"]
["HIP1"]
["IMMT"]
["LRRC8A"]
["MCEE"]
["MCPH1"]
["MDC1"]
["MICU1"]
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["NINJ1"]
["NMB"]
["NTS"]
["ORC4"]
["PCLO"]
["PECAM1"]
["PLA2G12A"]
["PNPLA3"]
["RAB1B"]
["RAB33B"]
["RBM10"]
["REEP2"]
["RNF135"]
["RPGR"]
["SH3BP2"]
["SIGLEC8"]
["SLC25A6"]
["SNRPE"]
["STK25"]
["STX11"]
["TBC1D1"]
["TBCD"]
["TFEB"]
["TRAPPC6B"]
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["UBR5"]
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["CD58"]
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["CLC"]
["CLDN3"]
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["CNN1"]
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["FKRP"]
["GK2"]
["HMGN1"]
["HPR"]
["INF2"]
["KIF3A"]
["MKS1"]
["MMAA"]
["NES"]
["ORMDL3"]
["PANK1"]
["PLEK"]
["POGLUT1"]
["PPY"]
["RAB1A"]
["RAB35"]
["RAB4A"]
["RAD9A"]
["RAI1"]
["REEP1"]
["SCARA5"]
["SETMAR"]
["SETX"]
["SGMS1"]
["SLC35C1"]
["SLCO3A1"]
["SLCO4A1"]
["SMARCA1"]
["SSR2"]
["TRAPPC3"]
["TRAPPC4"]
["AKTIP"]
["BBS9"]
["CC2D2A"]
["CCDC8"]
["CD68"]
["CEP120"]
["CERS3"]
["CNTN3"]
["CORO1C"]
["DOLK"]
["DYNC2LI1"]
["EME1"]
["ERGIC1"]
["FMO2"]
["FUZ"]
["GOLM1"]
["GTPBP1"]
["GYG2"]
["HOOK1"]
["IBTK"]
["IFT172"]
["INTS8"]
["KANSL1"]
["KIF17"]
["LDB1"]
["LDB2"]
["MID2"]
["NIF3L1"]
["NIPA1"]
["NSUN4"]
["NYX"]
["PDLIM5"]
["PHC2"]
["PMM1"]
["RAB38"]
["RAB3D"]
["RAB9A"]
["RBMS1"]
["RNF41"]
["RPGRIP1L"]
["RUNX1T1"]
["SH3PXD2A"]
["SLC25A17"]
["SPG11"]
["SUN1"]
["TCTN2"]
["TELO2"]
["TEX14"]
["THEM4"]
["TMEM106B"]
["TOE1"]
["TRAPPC9"]
["UGT3A1"]
["UNC13A"]
["VPREB1"]
["ABHD11"]
["BBS1"]
["CFDP1"]
["EVC"]
["EYA3"]
["FOXI1"]
["FUT4"]
["GPM6B"]
["HAO2"]
["HNRNPH2"]
["IFIT3"]
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["PNOC"]
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["RAB32"]
["RAB39B"]
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["SLC8B1"]
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["TRAPPC12"]
["TRAPPC6A"]
["TRO"]
["TTC21B"]
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["YTHDF2"]
["ACKR1"]
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["CORT"]
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["KIAA0586"]
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["SUPT20H"]
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["TRMT112"]
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["ZNF141"]
["ABHD14A"]
["C4orf19"]
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["MTERF4"]
["OR51B5"]
["PPP1R3E"]
["RAB19"]
["SNX22"]
["TEX12"]
["TRIM50"]
["ZBTB47"]
["ZNF506"]
["ZNF771"]
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["COPRS"]
["CSH2"]
["KATNBL1"]
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["NKX1-1"]
["RAB7B"]
["SNURF"]
["TMEM129"]
["URB1"]
["DYNC2I2"]
["EID1"]
["ELOA"]
["FAM193A"]
["FAM219B"]
["FAM53A"]
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["GTF2IRD2B"]
["H4C1"]
["IFT22"]
["OR51B6"]
["PGBD2"]
["RERGL"]
["RFX8"]
["ZNF215"]
["ZNF672"]
["ATP5IF1"]
["DCAF12L1"]
["DYNC2I1"]
["DYNLT2B"]
["DZANK1"]
["FAM221A"]
["POM121C"]
["PRORP"]
["SPDYE1"]
["TRIM74"]
["C4orf48"]
["H2AC4"]
["PLPP5"]
["REC114"]
["SPDYE2"]
["SSC4D"]
["TRIM73"]
["CCDC152"]
["GRAPL"]
["TAFA1"]
["CAVIN4"]
["FAM234B"]
["H2BC3"]
["IFTAP"]
["PSME3IP1"]
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["C1orf220"]
["CARMIL3"]
["NSUN5P2"]
["PHAF1"]
["TRAPPC3L"]
["CFAP161"]
["ETFRF1"]
["GASK1A"]
["MEI4"]
["RCC1L"]
["DNAI7"]
["SPATA31A3"]
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["COLCA1"]
["COLCA2"]
["MIR122"]
["MIR150"]
["MIR223"]
["MIR326"]
["CENPBD1P"]
["GOLGA8F"]
["GOLGA8G"]
["MIR139"]
["MIR328"]
["MIR346"]
["MEG8"]
["MIR181A1"]
["MIR197"]
["MIR425"]
["NSUN5P1"]
["STAG3L2"]
["MIR451A"]
["CLRN1-AS1"]
["LINC00243"]
["MIR296"]
["MIR299"]
["MIR494"]
["MIR519D"]
["STAG3L3"]
["TRAPPC2B"]
["WHAMMP3"]
["ABHD11-AS1"]
["MIR361"]
["MIR500A"]
["RNU11"]
["RNU6ATAC"]
["LINC00851"]
["MIR506"]
["MIR548AA1"]
["SNORD28"]
["LBX1-AS1"]
["SNORD64"]
["SPDYE7P"]
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["HLX-AS1"]
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["SNORD109A"]
["SNORD109B"]
["SNORD115-2"]
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["MIR4260"]
["PWARSN"]
["SNORD115-10"]
["SNORD115-11"]
["SNORD115-12"]
["SNORD115-13"]
["SNORD115-14"]
["SNORD115-15"]
["SNORD115-16"]
["SNORD115-17"]
["SNORD115-18"]
["SNORD115-19"]
["SNORD115-20"]
["SNORD115-21"]
["SNORD115-22"]
["SNORD115-23"]
["SNORD115-25"]
["SNORD115-26"]
["SNORD115-29"]
["SNORD115-3"]
["SNORD115-30"]
["SNORD115-31"]
["SNORD115-32"]
["SNORD115-33"]
["SNORD115-34"]
["SNORD115-35"]
["SNORD115-36"]
["SNORD115-37"]
["SNORD115-38"]
["SNORD115-39"]
["SNORD115-4"]
["SNORD115-40"]
["SNORD115-41"]
["SNORD115-42"]
["SNORD115-43"]
["SNORD115-44"]
["SNORD115-48"]
["SNORD115-5"]
["SNORD115-6"]
["SNORD115-7"]
["SNORD115-8"]
["GOLGA8EP"]
["LOC124902337"]
["SPDYE14"]
["SPDYE8"]
["SPDYE10"]
["SPDYE12"]
["WHSC1L2P"]
["GTF2IP4"]
["LOC124902571"]
["SPDYE13"]
["SPDYE15"]
["SPDYE9"]
["EIF4HP1"]
["NPAP1L"]
["RNU12-2P"]
["ENSG00000266919"]
["GK6P"]
["ANCR"]
["AZF1"]
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["AFD1"]
["AGMX2"]
["EGID-105180392"]
["HBB-HS-111"]
["LOC106029311"]
["LOC106029313"]
["LOC106728418"]
["LOC107133509"]
["LOC108228208"]
["LOC108228209"]
["WHCR"]
["DEL17Q11.2"]
["DYRK1A"]
["CSNK1D"]
["CD247"]
["ATP1B1"]
["IKBKG"]
["SCNN1A"]
["C5"]
["GNB3"]
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["POU2F1"]
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["NME7"]
["UCK2"]
["MPZL1"]
["SCGB1A1"]
["BLZF1"]
["CREG1"]
["GPA33"]
["GPR161"]
["LIN7C"]
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["DPT"]
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["POGK"]
["XCL1"]
["MAEL"]
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["FAM78B"]
["RPL37AP7"]
["FRA1H"]
["LOC284685"]
["CTSB"]
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["CASP7"]
["BCL2A1"]
["IRAK1"]
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["FOSL2"]
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["METTL3"]
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["CTNNBIP1"]
["NFIC"]
["SLC10A7"]
["DCSTAMP"]
["THNSL2"]
["MIR22HG"]
["MIR449A"]
["MIR486-1"]
["LOC106627981"]
["ERBB2"]
["JAK1"]
["CDK2"]
["FGFR4"]
["ABCC1"]
["BRD4"]
["CSF2RB"]
["HSP90AA1"]
["MAPKAPK2"]
["PLK4"]
["ROR2"]
["TNNT2"]
["FHL2"]
["FKBP5"]
["GCGR"]
["PDX1"]
["PINK1"]
["SLC20A2"]
["BECN1"]
["CCNA2"]
["CRAT"]
["EPHA3"]
["MUTYH"]
["PTS"]
["PXN"]
["UGT1A9"]
["CYP4F2"]
["FABP4"]
["FADS1"]
["FADS2"]
["TXN2"]
["FABP3"]
["GATAD2B"]
["NRCAM"]
["PPP3R1"]
["SETD7"]
["SLC14A1"]
["SORT1"]
["UBE2D2"]
["CD47"]
["ELK1"]
["FMOD"]
["GPR68"]
["PPP2R2C"]
["STC2"]
["WNT7B"]
["GPR55"]
["JUNB"]
["LTBR"]
["RPN2"]
["SHOC2"]
["WWP1"]
["CDAN1"]
["CYP4F11"]
["FBXO32"]
["OSTF1"]
["SLA2"]
["BCL2L14"]
["HSPB7"]
["SLA"]
["THRAP3"]
["GPR182"]
["GREB1"]
["RHOU"]
["GPR173"]
["GPX6"]
["ZNF516"]
["DCHS2"]
["FABP12"]
["FAM9B"]
["CDIN1"]
["LINC00311"]
["MIR106A"]
["MIR450B"]
["MIR19B2"]
["PTCSC2"]
["LINC01435"]
["LOC100420587"]
["ST2"]
["HDLC3"]
["MUC1"]
["PRMT7"]
["HOXD9"]
["LUZP2"]
["CDK5"]
["LCK"]
["EPHB2"]
["NFKB2"]
["ZAP70"]
["ACVRL1"]
["CDH1"]
["CTH"]
["NFKBIA"]
["PLG"]
["PPP2CA"]
["SLC1A3"]
["ADAM9"]
["ITPR1"]
["KIF11"]
["CA1"]
["FGR"]
["GLUL"]
["LYN"]
["MVK"]
["PDE2A"]
["PIK3CB"]
["PKD2"]
["PTPN12"]
["TBP"]
["BCL2L1"]
["DES"]
["DHCR7"]
["DVL1"]
["EPHA1"]
["F13A1"]
["GALNT2"]
["HTR1A"]
["NPY1R"]
["PDE10A"]
["PPIA"]
["PPP1CA"]
["SCN4A"]
["TGFBI"]
["XDH"]
["ALPI"]
["ATF2"]
["CCNB1"]
["CD81"]
["CNTN2"]
["CTSS"]
["DVL2"]
["GLO1"]
["GRM8"]
["HTRA2"]
["PAK2"]
["PTPRS"]
["SFN"]
["TAT"]
["ACSS2"]
["ANGPTL4"]
["CD151"]
["E2F4"]
["FDFT1"]
["GCLC"]
["IDO1"]
["PDE1C"]
["PDE4B"]
["RORC"]
["UBE2D1"]
["ZBTB16"]
["ACTR2"]
["ARRB1"]
["ATP6AP1"]
["BCL2L11"]
["CD209"]
["CDKN3"]
["CEACAM5"]
["CLCNKB"]
["COX5A"]
["CRLF1"]
["EEF1A1"]
["FGF5"]
["GDF2"]
["GNE"]
["HRH2"]
["HTR1B"]
["ITIH4"]
["MB"]
["OPRD1"]
["PDE4C"]
["PDE7A"]
["PDGFA"]
["PROX1"]
["SIRPA"]
["SKP2"]
["TPH1"]
["ULK1"]
["AKR1C1"]
["ANP32A"]
["BMP5"]
["CD37"]
["CD63"]
["CD82"]
["DIO1"]
["GABARAP"]
["LHX3"]
["LTB4R2"]
["MACF1"]
["MYF6"]
["PPBP"]
["QKI"]
["RAMP2"]
["SLC23A2"]
["SPTB"]
["SULF1"]
["SULT1A1"]
["USP11"]
["VANGL2"]
["ARR3"]
["CHRDL1"]
["ETS2"]
["FGF7"]
["FLVCR2"]
["FZR1"]
["GLYAT"]
["GPX7"]
["IL22"]
["MAP1LC3A"]
["MAP1LC3B"]
["MARCO"]
["NADSYN1"]
["NMBR"]
["PDE1A"]
["PDE8A"]
["PSMC4"]
["PTPN4"]
["PTPRE"]
["SASH1"]
["SLC26A9"]
["SLC41A1"]
["SLC6A14"]
["SOX11"]
["TGFB1I1"]
["TLN1"]
["TRPV2"]
["TUBGCP6"]
["AFM"]
["ARFGAP3"]
["CST6"]
["DHRS2"]
["FGFBP1"]
["INPP5J"]
["PEMT"]
["PVALB"]
["ASIC2"]
["CD53"]
["DBF4"]
["DUSP19"]
["FBXL4"]
["ITPK1"]
["KLF11"]
["MYF5"]
["MYOG"]
["NUCB2"]
["TAOK3"]
["UGT1A3"]
["ZFYVE16"]
["CCN2"]
["CST7"]
["DOCK5"]
["NACA"]
["PDE7B"]
["TET1"]
["TSLP"]
["TXNIP"]
["ABO"]
["CST8"]
["FBXO15"]
["MBIP"]
["POMGNT2"]
["RNF185"]
["SERPINB4"]
["TSPAN4"]
["TWSG1"]
["CAPNS2"]
["ST6GALNAC3"]
["TRIM3"]
["TSPAN32"]
["CD24"]
["GIMAP1"]
["LRRC17"]
["TRIM16"]
["PRDM11"]
["TSPAN17"]
["UQCC1"]
["C10orf88"]
["MAP1LC3C"]
["METTL21C"]
["PVT1"]
["FAM227B"]
["PART1"]
["SERHL"]
["IZUMO3"]
["MIR141"]
["MIR146A"]
["MIR149"]
["MIR185"]
["MIR499A"]
["MIR99A"]
["MIR125B1"]
["MIR130A"]
["MIR431"]
["MIR101-1"]
["MIR148A"]
["MIR335"]
["MIR337"]
["SNHG16"]
["MIR7-1"]
["MIR7-3"]
["MIR765"]
["MIR101-2"]
["MIR1249"]
["MIR1271"]
["MIR1301"]
["MIR502"]
["MIR7-2"]
["MIR1179"]
["LINC00314"]
["MCF2L-AS1"]
["GULOP"]
["LINC00609"]
["MIR920"]
["SEMA3B-AS1"]
["LINC01512"]
["MIR664A"]
["DVL1P1"]
["MIR4485"]
["LINC02381"]
["REG1CP"]
["NM"]
["GH-LCR"]
["PDB4"]
["ATP2B1"]
["MPPED2"]
["MDS2"]

{"sheet":"S3( common Targets)","index":2,"n_rows":92,"n_cols":1,"rows_kept":92,"flags":["formulas_cached_only"]}
["91 common elements in \"Resveratrol\" and \"Osteoporosis\":"]
["PTGS1"]
["PTGS2"]
["NCOA2"]
["RELA"]
["STAT3"]
["AKT1"]
["VEGFA"]
["CCND1"]
["BCL2"]
["BCL2L1"]
["CDKN1A"]
["EIF6"]
["BAX"]
["CASP9"]
["PLAU"]
["MMP2"]
["MMP9"]
["MAPK3"]
["MAPK1"]
["IL10"]
["IL6"]
["CASP3"]
["MAPK8"]
["NFKBIA"]
["ODC1"]
["XDH"]
["CAT"]
["STAT1"]
["RUNX1T1"]
["EDN1"]
["FOXO1"]
["PPARG"]
["CTNNB1"]
["MYC"]
["CYP1A1"]
["IL1B"]
["SELE"]
["VCAM1"]
["PRKCD"]
["CXCL8"]
["BRCA1"]
["XRCC6"]
["PRKCB"]
["PECAM1"]
["BIRC5"]
["NOS3"]
["PTPN1"]
["BCL2A1"]
["HGF"]
["CYP1B1"]
["CCNB1"]
["DDIT3"]
["PLAT"]
["IL1A"]
["MPO"]
["NFE2L2"]
["AHR"]
["PRKAG2"]
["SLC2A4"]
["PPARA"]
["CRP"]
["PON1"]
["CD80"]
["CCNE1"]
["NTRK1"]
["KLF10"]
["SREBF1"]
["ADIPOR1"]
["ADIPOR2"]
["JAK1"]
["AGTR1"]
["IRS1"]
["CFLAR"]
["MTOR"]
["CCR2"]
["EIF2S1"]
["PTGES"]
["BCL2L11"]
["TNFSF10"]
["TNFRSF10A"]
["TRAF2"]
["CDC42"]
["BSG"]
["CD28"]
["NR1H3"]
["PAPPA"]
["SPARC"]
["BRCA2"]
["AAGAB"]
["TGFA"]
["CD320"]

{"sheet":"S4(GO)","index":3,"n_rows":1892,"n_cols":11,"rows_kept":1892,"flags":["formulas_cached_only"]}
["id","Term","Category","ListHits","ListTotal","PopHits","PopTotal","p-value","q-value","Enrichment_score","geneID"]
["GO:0019221","cytokine-mediated signaling pathway","biological_process",26,91,283,18684,{"v":2.58843333199102e-26,"d":"2.59E-26"},{"v":4.89472743079502e-23,"d":"4.89E-23"},18.8632004038364,"PTGS2;RELA;STAT3;AKT1;VEGFA;CCND1;BCL2;BCL2L1;CDKN1A;MMP2;MMP9;IL10;IL6;CASP3;STAT1;FOXO1;MYC;IL1B;VCAM1;CXCL8;BIRC5;HGF;IL1A;CD80;JAK1;CCR2"]
["GO:0043066","negative regulation of apoptotic process","biological_process",23,91,475,18684,{"v":5.26271044787926e-17,"d":"5.26E-17"},{"v":4.97589272846984e-14,"d":"4.98E-14"},9.94174667437825,"RELA;AKT1;VEGFA;BCL2;BCL2L1;CDKN1A;MMP9;IL10;IL6;CASP3;MAPK8;NFKBIA;CAT;FOXO1;CTNNB1;MYC;BIRC5;BCL2A1;HGF;MPO;NTRK1;CFLAR;CD28"]
["GO:0007568","aging","biological_process",14,91,153,18684,{"v":2.07142592138648e-14,"d":"2.07E-14"},{"v":1.30568880578061e-11,"d":"1.31E-11"},18.7873303167421,"RELA;AKT1;MAPK3;MAPK1;IL10;CAT;CYP1A1;VCAM1;BCL2A1;MPO;NFE2L2;NTRK1;SREBF1;EIF2S1"]
["GO:0097192","extrinsic apoptotic signaling pathway in absence of ligand","biological_process",8,91,30,18684,{"v":1.23970787496452e-12,"d":"1.24E-12"},{"v":5.7906904912828e-10,"d":"5.79E-10"},54.7516483516484,"BCL2;BCL2L1;BAX;CASP9;CASP3;BCL2A1;IL1A;BCL2L11"]
["GO:0042493","response to drug","biological_process",15,91,255,18684,{"v":1.53111858574373e-12,"d":"1.53E-12"},{"v":5.7906904912828e-10,"d":"5.79E-10"},12.0775694893342,"RELA;CCND1;BCL2;CDKN1A;IL10;CASP3;CAT;PPARG;CTNNB1;MYC;CYP1A1;CCNB1;NTRK1;SREBF1;ADIPOR2"]
["GO:0045893","positive regulation of transcription, DNA-templated","biological_process",21,91,632,18684,{"v":2.25369873368901e-12,"d":"2.25E-12"},{"v":7.10290717567652e-10,"d":"7.10E-10"},6.82229795520935,"RELA;STAT3;AKT1;MAPK1;IL10;IL6;STAT1;FOXO1;PPARG;CTNNB1;MYC;IL1B;BRCA1;XRCC6;PRKCB;DDIT3;AHR;PPARA;CD80;NR1H3;BRCA2"]
["GO:0010628","positive regulation of gene expression","biological_process",17,91,382,18684,{"v":3.87179390890788e-12,"d":"3.87E-12"},{"v":1.04593746882069e-09,"d":"1.05E-09"},9.13721880214027,"STAT3;AKT1;VEGFA;MAPK3;MAPK1;IL6;MAPK8;MYC;IL1B;CXCL8;BRCA1;NOS3;IL1A;NFE2L2;CRP;MTOR;CD28"]
["GO:1902042","negative regulation of extrinsic apoptotic signaling pathway via death domain receptors","biological_process",8,91,38,18684,{"v":1.00353989761521e-11,"d":"1.00E-11"},{"v":1.89769394639036e-09,"d":"1.90E-09"},43.224985540775,"BCL2L1;BRCA1;NOS3;HGF;CFLAR;TNFSF10;TNFRSF10A;TRAF2"]
["GO:0006915","apoptotic process","biological_process",19,91,553,18684,{"v":1.6595632134189e-11,"d":"1.66E-11"},{"v":2.85294003325013e-09,"d":"2.85E-09"},7.05434890606681,"BCL2;BAX;CASP9;MAPK3;MAPK1;CASP3;NFKBIA;FOXO1;IL1B;PRKCD;BRCA1;PRKCB;BIRC5;IL1A;AHR;CFLAR;BCL2L11;TNFSF10;TNFRSF10A"]
["GO:0045944","positive regulation of transcription by RNA polymerase II","biological_process",25,91,1110,18684,{"v":6.20600121708832e-11,"d":"6.21E-11"},{"v":7.94575244366026e-09,"d":"7.95E-09"},4.62429462429462,"NCOA2;RELA;STAT3;AKT1;VEGFA;MAPK3;IL6;NFKBIA;STAT1;EDN1;FOXO1;PPARG;CTNNB1;MYC;BRCA1;XRCC6;HGF;DDIT3;IL1A;NFE2L2;PPARA;KLF10;SREBF1;CD28;NR1H3"]
["GO:0032496","response to lipopolysaccharide","biological_process",11,91,137,18684,{"v":6.30281790877334e-11,"d":"6.30E-11"},{"v":7.94575244366026e-09,"d":"7.95E-09"},16.4854415657335,"CASP3;EDN1;CYP1A1;IL1B;SELE;VCAM1;NOS3;MPO;ADIPOR2;PTGES;SPARC"]
["GO:0071456","cellular response to hypoxia","biological_process",10,91,111,18684,{"v":1.55891917681298e-10,"d":"1.56E-10"},{"v":1.73406833138432e-08,"d":"1.73E-08"},18.4971784971785,"PTGS2;AKT1;VEGFA;BCL2;EDN1;MYC;CCNB1;SLC2A4;CFLAR;MTOR"]
["GO:0071356","cellular response to tumor necrosis factor","biological_process",10,91,125,18684,{"v":5.07554607140473e-10,"d":"5.08E-10"},{"v":5.33214312279242e-08,"d":"5.33E-08"},16.4254945054945,"RELA;AKT1;MAPK3;MAPK1;EDN1;VCAM1;CXCL8;BRCA1;NFE2L2;SLC2A4"]
["GO:0032868","response to insulin","biological_process",8,91,62,18684,{"v":6.30956705877675e-10,"d":"6.31E-10"},{"v":6.06521358960861e-08,"d":"6.07E-08"},26.4927330733782,"RELA;EIF6;IL10;CAT;PPARA;IRS1;MTOR;TNFSF10"]
["GO:0045766","positive regulation of angiogenesis","biological_process",10,91,128,18684,{"v":6.41482135336712e-10,"d":"6.41E-10"},{"v":6.06521358960861e-08,"d":"6.07E-08"},16.040521978022,"VEGFA;IL1B;CXCL8;BRCA1;PRKCB;NOS3;HGF;CYP1B1;IL1A;NFE2L2"]
["GO:0008630","intrinsic apoptotic signaling pathway in response to DNA damage","biological_process",7,91,42,18684,{"v":1.20750067174378e-09,"d":"1.21E-09"},{"v":1.08732560488928e-07,"d":"1.09E-07"},34.2197802197802,"BCL2;BCL2L1;BAX;CASP9;BRCA1;BCL2A1;BCL2L11"]
["GO:0009636","response to toxic substance","biological_process",8,91,75,18684,{"v":2.99047348853034e-09,"d":"2.99E-09"},{"v":2.41762761050506e-07,"d":"2.42E-07"},21.9006593406593,"BCL2;CDKN1A;BAX;MAPK3;MAPK1;CYP1B1;AHR;PON1"]
["GO:0010745","negative regulation of macrophage derived foam cell differentiation","biological_process",5,91,13,18684,{"v":3.06044577162666e-09,"d":"3.06E-09"},{"v":2.41762761050506e-07,"d":"2.42E-07"},78.9687235841082,"NFKBIA;PPARG;PPARA;CRP;NR1H3"]
["GO:0010575","positive regulation of vascular endothelial growth factor production","biological_process",6,91,27,18684,{"v":3.07877673866601e-09,"d":"3.08E-09"},{"v":2.41762761050506e-07,"d":"2.42E-07"},45.6263736263736,"PTGS2;IL6;IL1B;BRCA1;CYP1B1;IL1A"]
["GO:0051091","positive regulation of DNA-binding transcription factor activity","biological_process",9,91,110,18684,{"v":3.19622899326423e-09,"d":"3.20E-09"},{"v":2.41762761050506e-07,"d":"2.42E-07"},16.7988011988012,"AKT1;IL10;IL6;EDN1;PPARG;CTNNB1;IL1B;DDIT3;TRAF2"]
["GO:0006954","inflammatory response","biological_process",14,91,388,18684,{"v":5.50297523873504e-09,"d":"5.50E-09"},{"v":3.85412080609184e-07,"d":"3.85E-07"},7.40840602696273,"PTGS1;PTGS2;RELA;STAT3;AKT1;IL6;IL1B;SELE;CXCL8;IL1A;NFE2L2;CRP;AGTR1;CCR2"]
["GO:0032743","positive regulation of interleukin-2 production","biological_process",6,91,30,18684,{"v":6.1038749448255e-09,"d":"6.10E-09"},{"v":4.12229554309465e-07,"d":"4.12E-07"},41.0637362637363,"IL1B;IL1A;CD80;CCR2;TRAF2;CD28"]
["GO:0043065","positive regulation of apoptotic process","biological_process",13,91,335,18684,{"v":8.5608072972969e-09,"d":"8.56E-09"},{"v":5.58223675834084e-07,"d":"5.58E-07"},7.96759061833689,"AKT1;BAX;CASP9;MMP9;IL6;CASP3;MAPK8;FOXO1;CTNNB1;CYP1B1;BCL2L11;TNFSF10;TNFRSF10A"]
["GO:0006919","activation of cysteine-type endopeptidase activity involved in apoptotic process","biological_process",8,91,86,18684,{"v":9.00455822105355e-09,"d":"9.00E-09"},{"v":5.67587319867076e-07,"d":"5.68E-07"},19.0994122156913,"BAX;CASP9;XDH;PPARG;CFLAR;TNFSF10;TNFRSF10A;TRAF2"]
["GO:0034614","cellular response to reactive oxygen species","biological_process",6,91,35,18684,{"v":1.63631207901155e-08,"d":"1.64E-08"},{"v":9.53983836301069e-07,"d":"9.54E-07"},35.1974882260597,"AKT1;MMP2;MMP9;MAPK3;MAPK1;MAPK8"]
["GO:0001934","positive regulation of protein phosphorylation","biological_process",10,91,179,18684,{"v":1.66480521406321e-08,"d":"1.66E-08"},{"v":9.53983836301069e-07,"d":"9.54E-07"},11.4703173921051,"AKT1;VEGFA;CCND1;MMP9;MAPK3;IL1B;PECAM1;HGF;NTRK1;ADIPOR2"]
["GO:0046627","negative regulation of insulin receptor signaling pathway","biological_process",6,91,36,18684,{"v":1.95592315098945e-08,"d":"1.96E-08"},{"v":1.0567573367203e-06,"d":"1.06E-06"},34.2197802197802,"RELA;IL1B;PRKCD;PRKCB;PTPN1;IRS1"]
["GO:0006974","cellular response to DNA damage stimulus","biological_process",11,91,243,18684,{"v":2.72092119030143e-08,"d":"2.72E-08"},{"v":1.42923943635e-06,"d":"1.43E-06"},9.29426129426129,"AKT1;CCND1;BCL2;CDKN1A;CASP9;MAPK1;CASP3;FOXO1;MYC;BRCA1;DDIT3"]
["GO:0045471","response to ethanol","biological_process",8,91,102,18684,{"v":3.49320350376968e-08,"d":"3.49E-08"},{"v":1.78531022314283e-06,"d":"1.79E-06"},16.1034259857789,"CCND1;CAT;VCAM1;SLC2A4;PPARA;SREBF1;ADIPOR2;SPARC"]
["GO:0042593","glucose homeostasis","biological_process",8,91,103,18684,{"v":3.77241102176125e-08,"d":"3.77E-08"},{"v":1.8772708531975e-06,"d":"1.88E-06"},15.9470820441694,"STAT3;AKT1;IL6;PPARG;SLC2A4;ADIPOR1;ADIPOR2;IRS1"]
["GO:0071222","cellular response to lipopolysaccharide","biological_process",9,91,150,18684,{"v":4.87267852688517e-08,"d":"4.87E-08"},{"v":2.36262438316406e-06,"d":"2.36E-06"},12.3191208791209,"RELA;IL10;IL6;MAPK8;IL1B;CXCL8;IL1A;CD80;NR1H3"]
["GO:0034097","response to cytokine","biological_process",6,91,42,18684,{"v":5.1457363796689e-08,"d":"5.15E-08"},{"v":2.43264687348847e-06,"d":"2.43E-06"},29.331240188383,"RELA;BCL2;BCL2L1;STAT1;PTGES;SPARC"]
["GO:0034198","cellular response to amino acid starvation","biological_process",6,91,45,18684,{"v":7.89670630585899e-08,"d":"7.90E-08"},{"v":3.64211503033643e-06,"d":"3.64E-06"},27.3758241758242,"CDKN1A;MAPK3;MAPK1;MAPK8;MTOR;EIF2S1"]
["GO:0051092","positive regulation of NF-kappaB transcription factor activity","biological_process",9,91,160,18684,{"v":8.50309333818476e-08,"d":"8.50E-08"},{"v":3.82841654821604e-06,"d":"3.83E-06"},11.5491758241758,"RELA;STAT3;IL6;CAT;IL1B;PRKCB;NTRK1;CFLAR;TRAF2"]
["GO:0071398","cellular response to fatty acid","biological_process",5,91,24,18684,{"v":9.6891824432295e-08,"d":"9.69E-08"},{"v":4.15586701307098e-06,"d":"4.16E-06"},42.7747252747253,"EDN1;CCNB1;SREBF1;ADIPOR2;IRS1"]
["GO:0010507","negative regulation of autophagy","biological_process",6,91,47,18684,{"v":1.03292305454435e-07,"d":"1.03E-07"},{"v":4.15586701307098e-06,"d":"4.16E-06"},26.2108954874912,"STAT3;AKT1;BCL2;IL10;HGF;MTOR"]
["GO:0043525","positive regulation of neuron apoptotic process","biological_process",6,91,47,18684,{"v":1.03292305454435e-07,"d":"1.03E-07"},{"v":4.15586701307098e-06,"d":"4.16E-06"},26.2108954874912,"BAX;CASP3;CTNNB1;DDIT3;BCL2L11;CDC42"]
["GO:0042304","regulation of fatty acid biosynthetic process","biological_process",4,91,10,18684,{"v":1.08121396138221e-07,"d":"1.08E-07"},{"v":4.25953250202865e-06,"d":"4.26E-06"},82.1274725274725,"EIF6;PRKAG2;ADIPOR1;ADIPOR2"]
["GO:0051384","response to glucocorticoid","biological_process",6,91,51,18684,{"v":1.70562515292339e-07,"d":"1.71E-07"},{"v":6.58232074322066e-06,"d":"6.58E-06"},24.1551389786684,"BCL2;IL10;IL6;CASP3;PAPPA;SPARC"]
["GO:0035094","response to nicotine","biological_process",5,91,29,18684,{"v":2.65566491520768e-07,"d":"2.66E-07"},{"v":9.65742760511099e-06,"d":"9.66E-06"},35.3997726411519,"BCL2;MAPK1;CASP3;EDN1;VCAM1"]
["GO:0045840","positive regulation of mitotic nuclear division","biological_process",5,91,29,18684,{"v":2.65566491520768e-07,"d":"2.66E-07"},{"v":9.65742760511099e-06,"d":"9.66E-06"},35.3997726411519,"EDN1;IL1B;IL1A;CD28;TGFA"]
["GO:0008285","negative regulation of cell population proliferation","biological_process",12,91,385,18684,{"v":3.60097047315664e-07,"d":"3.60E-07"},{"v":1.27478363440513e-05,"d":"1.27E-05"},6.39954331382903,"CDKN1A;IL10;IL6;CTNNB1;IL1B;CXCL8;NOS3;CYP1B1;IL1A;NTRK1;KLF10;PTGES"]
["GO:0036499","PERK-mediated unfolded protein response","biological_process",4,91,13,18684,{"v":3.64031286398081e-07,"d":"3.64E-07"},{"v":1.27478363440513e-05,"d":"1.27E-05"},63.1749788672866,"CXCL8;DDIT3;NFE2L2;EIF2S1"]
["GO:0006468","protein phosphorylation","biological_process",13,91,468,18684,{"v":4.19335588742433e-07,"d":"4.19E-07"},{"v":1.4417519969308e-05,"d":"1.44E-05"},5.7032967032967,"AKT1;CCND1;MAPK3;MAPK1;MAPK8;PRKCD;PRKCB;BIRC5;PRKAG2;CCNE1;NTRK1;JAK1;MTOR"]
["GO:2001240","negative regulation of extrinsic apoptotic signaling pathway in absence of ligand","biological_process",5,91,32,18684,{"v":4.45173028167171e-07,"d":"4.45E-07"},{"v":1.50325392190022e-05,"d":"1.50E-05"},32.081043956044,"AKT1;BCL2;BCL2L1;IL1B;IL1A"]
["GO:0070301","cellular response to hydrogen peroxide","biological_process",6,91,62,18684,{"v":5.57752249425726e-07,"d":"5.58E-07"},{"v":1.81846466148974e-05,"d":"1.82E-05"},19.8695498050337,"RELA;IL6;FOXO1;PRKCD;CYP1B1;NFE2L2"]
["GO:0031663","lipopolysaccharide-mediated signaling pathway","biological_process",5,91,34,18684,{"v":6.1042560065549e-07,"d":"6.10E-07"},{"v":1.93532297211087e-05,"d":"1.94E-05"},30.1939237233355,"AKT1;MAPK3;MAPK1;NFKBIA;IL1B"]
["GO:0042752","regulation of circadian rhythm","biological_process",6,91,63,18684,{"v":6.14063343874417e-07,"d":"6.14E-07"},{"v":1.93532297211087e-05,"d":"1.94E-05"},19.5541601255887,"MAPK8;PPARG;PPARA;KLF10;MTOR;NR1H3"]
["GO:0032270","positive regulation of cellular protein metabolic process","biological_process",4,91,15,18684,{"v":6.89805170637407e-07,"d":"6.90E-07"},{"v":2.06391308063145e-05,"d":"2.06E-05"},54.7516483516484,"AKT1;NFKBIA;AGTR1;NR1H3"]
["GO:0030522","intracellular receptor signaling pathway","biological_process",5,91,35,18684,{"v":7.09436013966389e-07,"d":"7.09E-07"},{"v":2.06391308063145e-05,"d":"2.06E-05"},29.331240188383,"STAT3;AHR;PPARA;SREBF1;NR1H3"]
["GO:0045429","positive regulation of nitric oxide biosynthetic process","biological_process",5,91,35,18684,{"v":7.09436013966389e-07,"d":"7.09E-07"},{"v":2.06391308063145e-05,"d":"2.06E-05"},29.331240188383,"PTGS2;AKT1;EDN1;IL1B;MTOR"]
["GO:2001244","positive regulation of intrinsic apoptotic signaling pathway","biological_process",5,91,35,18684,{"v":7.09436013966389e-07,"d":"7.09E-07"},{"v":2.06391308063145e-05,"d":"2.06E-05"},29.331240188383,"BCL2;BCL2L1;BAX;DDIT3;BCL2L11"]
["GO:0018107","peptidyl-threonine phosphorylation","biological_process",6,91,65,18684,{"v":7.40694288978185e-07,"d":"7.41E-07"},{"v":2.12220136432992e-05,"d":"2.12E-05"},18.952493660186,"AKT1;BCL2;MAPK1;MAPK8;PRKCD;MTOR"]
["GO:0001666","response to hypoxia","biological_process",8,91,153,18684,{"v":8.04943820049568e-07,"d":"8.05E-07"},{"v":2.27186382643841e-05,"d":"2.27E-05"},10.7356173238526,"VEGFA;PLAU;MMP2;CASP3;CAT;CYP1A1;VCAM1;PPARA"]
["GO:0001516","prostaglandin biosynthetic process","biological_process",4,91,16,18684,{"v":9.16317581524677e-07,"d":"9.16E-07"},{"v":2.54817139215171e-05,"d":"2.55E-05"},51.3296703296703,"PTGS1;PTGS2;EDN1;PTGES"]
["GO:0071276","cellular response to cadmium ion","biological_process",5,91,37,18684,{"v":9.45308421624923e-07,"d":"9.45E-07"},{"v":2.59069308013439e-05,"d":"2.59E-05"},27.7457677457677,"AKT1;MMP9;MAPK3;MAPK1;MAPK8"]
["GO:1902041","regulation of extrinsic apoptotic signaling pathway via death domain receptors","biological_process",4,91,17,18684,{"v":1.19380284510671e-06,"d":"1.19E-06"},{"v":3.22497311442398e-05,"d":"3.22E-05"},48.3102779573368,"CFLAR;TNFSF10;TNFRSF10A;TRAF2"]
["GO:0071407","cellular response to organic cyclic compound","biological_process",5,91,39,18684,{"v":1.23907349942828e-06,"d":"1.24E-06"},{"v":3.29506208798513e-05,"d":"3.30E-05"},26.3229078613694,"AKT1;CYP1A1;IL1B;CYP1B1;CCNB1"]
["GO:0045727","positive regulation of translation","biological_process",6,91,71,18684,{"v":1.25459793937033e-06,"d":"1.25E-06"},{"v":3.29506208798513e-05,"d":"3.30E-05"},17.350874477635,"EIF6;MAPK3;MAPK1;IL6;MTOR;CD28"]
["GO:0051591","response to cAMP","biological_process",5,91,40,18684,{"v":1.41066302456982e-06,"d":"1.41E-06"},{"v":3.63848081955289e-05,"d":"3.64E-05"},25.6648351648352,"RELA;STAT1;SREBF1;BSG;SPARC"]
["GO:0018105","peptidyl-serine phosphorylation","biological_process",8,91,165,18684,{"v":1.4238370208721e-06,"d":"1.42E-06"},{"v":3.63848081955289e-05,"d":"3.64E-05"},9.95484515484516,"AKT1;BCL2;MAPK3;MAPK1;MAPK8;PRKCD;PRKCB;MTOR"]
["GO:0032091","negative regulation of protein binding","biological_process",6,91,73,18684,{"v":1.47963555922274e-06,"d":"1.48E-06"},{"v":3.73065445665361e-05,"d":"3.73E-05"},16.8755080535902,"AKT1;CDKN1A;BAX;MAPK8;PRKCD;PPARA"]
["GO:0070102","interleukin-6-mediated signaling pathway","biological_process",4,91,18,18684,{"v":1.52917885378138e-06,"d":"1.53E-06"},{"v":3.80483843750078e-05,"d":"3.80E-05"},45.6263736263736,"STAT3;IL6;STAT1;JAK1"]
["GO:0007166","cell surface receptor signaling pathway","biological_process",9,91,227,18684,{"v":1.62605729582127e-06,"d":"1.63E-06"},{"v":3.99334330701042e-05,"d":"3.99E-05"},8.14038824611512,"MAPK3;MAPK1;EDN1;PECAM1;CD80;TNFSF10;TNFRSF10A;BSG;CD28"]
["GO:0035556","intracellular signal transduction","biological_process",11,91,372,18684,{"v":1.91532594866393e-06,"d":"1.92E-06"},{"v":4.58465996066266e-05,"d":"4.58E-05"},6.07125132931585,"AKT1;MAPK3;MAPK1;MAPK8;PRKCD;CXCL8;PRKCB;PRKAG2;CD80;JAK1;TGFA"]
["GO:0010165","response to X-ray","biological_process",4,91,20,18684,{"v":2.40322039210702e-06,"d":"2.40E-06"},{"v":5.47528886924623e-05,"d":"5.48E-05"},41.0637362637363,"CCND1;CDKN1A;CASP3;BRCA2"]
["GO:0014823","response to activity","biological_process",5,91,45,18684,{"v":2.56951229462756e-06,"d":"2.57E-06"},{"v":5.78446160611989e-05,"d":"5.78E-05"},22.8131868131868,"IL10;IL6;CAT;EDN1;MTOR"]
["GO:0043434","response to peptide hormone","biological_process",5,91,46,18684,{"v":2.87183594122549e-06,"d":"2.87E-06"},{"v":6.28416028339015e-05,"d":"6.28E-05"},22.3172479694219,"STAT3;STAT1;IRS1;BSG;SPARC"]
["GO:0050727","regulation of inflammatory response","biological_process",6,91,82,18684,{"v":2.93866942280301e-06,"d":"2.94E-06"},{"v":6.28416028339015e-05,"d":"6.28E-05"},15.0233181452694,"PTGS2;RELA;SELE;AGTR1;CCR2;PTGES"]
["GO:0001782","B cell homeostasis","biological_process",4,91,21,18684,{"v":2.95764286209267e-06,"d":"2.96E-06"},{"v":6.28416028339015e-05,"d":"6.28E-05"},39.1083202511774,"BCL2;BAX;CASP3;BCL2L11"]
["GO:0032094","response to food","biological_process",4,91,21,18684,{"v":2.95764286209267e-06,"d":"2.96E-06"},{"v":6.28416028339015e-05,"d":"6.28E-05"},39.1083202511774,"AKT1;CYP1A1;MPO;SREBF1"]
["GO:0050999","regulation of nitric-oxide synthase activity","biological_process",4,91,21,18684,{"v":2.95764286209267e-06,"d":"2.96E-06"},{"v":6.28416028339015e-05,"d":"6.28E-05"},39.1083202511774,"AKT1;IL1B;NOS3;IL1A"]
["GO:0051781","positive regulation of cell division","biological_process",5,91,47,18684,{"v":3.20142446929349e-06,"d":"3.20E-06"},{"v":6.72654852381553e-05,"d":"6.73E-05"},21.8424129062427,"VEGFA;CAT;IL1B;IL1A;TGFA"]
["GO:0019233","sensory perception of pain","biological_process",5,91,48,18684,{"v":3.56001003970405e-06,"d":"3.56E-06"},{"v":7.3977791044839e-05,"d":"7.40E-05"},21.3873626373626,"MAPK3;MAPK1;EDN1;CCR2;PTGES"]
["GO:0050731","positive regulation of peptidyl-tyrosine phosphorylation","biological_process",6,91,85,18684,{"v":3.62774990059469e-06,"d":"3.63E-06"},{"v":7.45660332828756e-05,"d":"7.46E-05"},14.493083387201,"VEGFA;IL6;PECAM1;HGF;CD80;MTOR"]
["GO:0019217","regulation of fatty acid metabolic process","biological_process",3,91,7,18684,{"v":3.85705279105128e-06,"d":"3.86E-06"},{"v":7.75924130625317e-05,"d":"7.76E-05"},87.9937205651491,"PRKAG2;PPARA;SREBF1"]
["GO:1903896","positive regulation of IRE1-mediated unfolded protein response","biological_process",3,91,7,18684,{"v":3.85705279105128e-06,"d":"3.86E-06"},{"v":7.75924130625317e-05,"d":"7.76E-05"},87.9937205651491,"BAX;PTPN1;BCL2L11"]
["GO:0042060","wound healing","biological_process",6,91,88,18684,{"v":4.44295793601552e-06,"d":"4.44E-06"},{"v":8.84382469158457e-05,"d":"8.84E-05"},13.999000999001,"CDKN1A;CASP3;PPARA;CFLAR;MTOR;SPARC"]
["GO:0050728","negative regulation of inflammatory response","biological_process",6,91,90,18684,{"v":5.06481109176785e-06,"d":"5.06E-06"},{"v":9.87377090158041e-05,"d":"9.87E-05"},13.6879120879121,"IL10;PPARG;PRKCD;HGF;PPARA;NR1H3"]
["GO:0034644","cellular response to UV","biological_process",5,91,52,18684,{"v":5.32122744867281e-06,"d":"5.32E-06"},0.000102677970463676,19.7421808960271,"BAX;CASP9;MYC;PRKCD;EIF2S1"]
["GO:0033129","positive regulation of histone phosphorylation","biological_process",3,91,8,18684,{"v":6.14949822291614e-06,"d":"6.15E-06"},0.00011418060503532,76.9945054945055,"MAPK3;IL1B;CCNB1"]
["GO:0038114","interleukin-21-mediated signaling pathway","biological_process",3,91,8,18684,{"v":6.14949822291614e-06,"d":"6.15E-06"},0.00011418060503532,76.9945054945055,"STAT3;STAT1;JAK1"]
["GO:0044321","response to leptin","biological_process",3,91,8,18684,{"v":6.14949822291614e-06,"d":"6.15E-06"},0.00011418060503532,76.9945054945055,"STAT3;CCND1;EDN1"]
["GO:0097194","execution phase of apoptosis","biological_process",4,91,25,18684,{"v":6.1588692298269e-06,"d":"6.16E-06"},0.00011418060503532,32.850989010989,"AKT1;CASP9;CASP3;CFLAR"]
["GO:0048661","positive regulation of smooth muscle cell proliferation","biological_process",5,91,54,18684,{"v":6.42563076823001e-06,"d":"6.43E-06"},0.000117969590123524,19.010989010989,"AKT1;IL6;STAT1;EDN1;MTOR"]
["GO:0010629","negative regulation of gene expression","biological_process",8,91,203,18684,{"v":6.64475373928002e-06,"d":"6.64E-06"},0.000120819512701716,8.09137660369188,"AKT1;VEGFA;CDKN1A;XDH;CXCL8;CCNB1;ADIPOR2;CD28"]
["GO:0010332","response to gamma radiation","biological_process",4,91,26,18684,{"v":7.25160824555292e-06,"d":"7.25E-06"},0.000130598011355625,31.5874894336433,"BCL2;BAX;MYC;BRCA2"]
["GO:0032869","cellular response to insulin stimulus","biological_process",6,91,97,18684,{"v":7.82230141060262e-06,"d":"7.82E-06"},0.000139546905353298,12.7001246176504,"AKT1;FOXO1;PPARG;SLC2A4;IRS1;CFLAR"]
["GO:0042981","regulation of apoptotic process","biological_process",8,91,209,18684,{"v":8.22508947619258e-06,"d":"8.23E-06"},0.000144484640759318,7.85908828014091,"AKT1;BAX;STAT1;BRCA1;BIRC5;BCL2L11;TNFRSF10A;TRAF2"]
["GO:0032757","positive regulation of interleukin-8 production","biological_process",5,91,57,18684,{"v":8.41019631586189e-06,"d":"8.41E-06"},0.000144484640759318,18.0104106419896,"RELA;STAT3;IL6;IL1B;DDIT3"]
["GO:0043200","response to amino acid","biological_process",4,91,27,18684,{"v":8.48111852156756e-06,"d":"8.48E-06"},0.000144484640759318,30.4175824175824,"RELA;CASP3;EDN1;MTOR"]
["GO:0090200","positive regulation of release of cytochrome c from mitochondria","biological_process",4,91,27,18684,{"v":8.48111852156756e-06,"d":"8.48E-06"},0.000144484640759318,30.4175824175824,"BAX;MMP9;BCL2L11;TNFSF10"]
["GO:2000379","positive regulation of reactive oxygen species metabolic process","biological_process",4,91,27,18684,{"v":8.48111852156756e-06,"d":"8.48E-06"},0.000144484640759318,30.4175824175824,"CDKN1A;XDH;NFE2L2;AGTR1"]
["GO:0010887","negative regulation of cholesterol storage","biological_process",3,91,9,18684,{"v":9.19168967629688e-06,"d":"9.19E-06"},0.000147300721846419,68.4395604395604,"PPARG;PPARA;NR1H3"]
["GO:0010888","negative regulation of lipid storage","biological_process",3,91,9,18684,{"v":9.19168967629688e-06,"d":"9.19E-06"},0.000147300721846419,68.4395604395604,"IL6;NFKBIA;CRP"]
["GO:0032308","positive regulation of prostaglandin secretion","biological_process",3,91,9,18684,{"v":9.19168967629688e-06,"d":"9.19E-06"},0.000147300721846419,68.4395604395604,"EDN1;IL1B;PTGES"]
["GO:0038113","interleukin-9-mediated signaling pathway","biological_process",3,91,9,18684,{"v":9.19168967629688e-06,"d":"9.19E-06"},0.000147300721846419,68.4395604395604,"STAT3;STAT1;JAK1"]
["GO:1904385","cellular response to angiotensin","biological_process",3,91,9,18684,{"v":9.19168967629688e-06,"d":"9.19E-06"},0.000147300721846419,68.4395604395604,"RELA;PRKCD;NFE2L2"]
["GO:0007165","signal transduction","biological_process",17,91,1038,18684,{"v":9.35956749423954e-06,"d":"9.36E-06"},0.000148730606147958,3.36263736263736,"STAT3;AKT1;PLAU;MAPK1;PPARG;IL1B;PRKCD;CXCL8;PRKCB;PECAM1;IRS1;PTGES;TNFSF10;TNFRSF10A;TRAF2;TGFA;CD320"]
["GO:0035924","cellular response to vascular endothelial growth factor stimulus","biological_process",4,91,28,18684,{"v":9.85786754626556e-06,"d":"9.86E-06"},0.000154252319039386,29.331240188383,"RELA;AKT1;VEGFA;VCAM1"]
["GO:0042102","positive regulation of T cell proliferation","biological_process",5,91,59,18684,{"v":9.97905244601788e-06,"d":"9.98E-06"},0.000154675312913277,17.3998882473459,"IL6;IL1B;VCAM1;CD80;CD28"]
["GO:0042127","regulation of cell population proliferation","biological_process",7,91,159,18684,{"v":1.25905183421585e-05,"d":"1.26E-05"},0.00019356642426847,9.03918722786647,"PTGS1;STAT3;PLAU;NFKBIA;STAT1;BRCA1;AGTR1"]
["GO:0006367","transcription initiation from RNA polymerase II promoter","biological_process",7,91,160,18684,{"v":1.31148935366556e-05,"d":"1.31E-05"},0.000198402109422526,8.98269230769231,"CCND1;CDKN1A;BAX;PPARG;CCNB1;PPARA;NR1H3"]
["GO:0000122","negative regulation of transcription by RNA polymerase II","biological_process",15,91,852,18684,{"v":1.45464585980127e-05,"d":"1.45E-05"},0.000218312327054301,3.61476551617397,"NCOA2;RELA;STAT3;VEGFA;CCND1;STAT1;EDN1;PPARG;MYC;DDIT3;PPARA;CCNE1;KLF10;SREBF1;NR1H3"]
["GO:0046427","positive regulation of receptor signaling pathway via JAK-STAT","biological_process",4,91,31,18684,{"v":1.49808720305208e-05,"d":"1.50E-05"},0.000221318976638396,26.4927330733782,"IL10;IL6;CYP1B1;ADIPOR1"]
["GO:0030335","positive regulation of cell migration","biological_process",8,91,228,18684,{"v":1.54806906820433e-05,"d":"1.55E-05"},0.00022662087971057,7.20416425679584,"STAT3;VEGFA;PLAU;MMP9;EDN1;IL1B;PECAM1;HGF"]
["GO:0016032","viral process","biological_process",11,91,464,18684,{"v":1.5579436468733e-05,"d":"1.56E-05"},0.00022662087971057,4.86746873815839,"RELA;STAT3;BAX;MAPK3;MAPK1;NFKBIA;STAT1;CTNNB1;NFE2L2;CFLAR;CCR2"]
["GO:1904707","positive regulation of vascular associated smooth muscle cell proliferation","biological_process",4,91,32,18684,{"v":1.70574004594284e-05,"d":"1.71E-05"},0.000246225528769306,25.6648351648352,"MMP2;MMP9;IL10;EDN1"]
["GO:0019371","cyclooxygenase pathway","biological_process",3,91,11,18684,{"v":1.79279131680685e-05,"d":"1.79E-05"},0.000251123583709759,55.996003996004,"PTGS1;PTGS2;PTGES"]
["GO:0070106","interleukin-27-mediated signaling pathway","biological_process",3,91,11,18684,{"v":1.79279131680685e-05,"d":"1.79E-05"},0.000251123583709759,55.996003996004,"STAT3;STAT1;JAK1"]
["GO:0070757","interleukin-35-mediated signaling pathway","biological_process",3,91,11,18684,{"v":1.79279131680685e-05,"d":"1.79E-05"},0.000251123583709759,55.996003996004,"STAT3;STAT1;JAK1"]
["GO:0150077","regulation of neuroinflammatory response","biological_process",3,91,11,18684,{"v":1.79279131680685e-05,"d":"1.79E-05"},0.000251123583709759,55.996003996004,"PTGS2;MMP9;IL6"]
["GO:0007566","embryo implantation","biological_process",4,91,33,18684,{"v":1.93380544875542e-05,"d":"1.93E-05"},0.000264987398811341,24.8871128871129,"MMP2;MMP9;IL1B;BSG"]
["GO:0070059","intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress","biological_process",4,91,33,18684,{"v":1.93380544875542e-05,"d":"1.93E-05"},0.000264987398811341,24.8871128871129,"BCL2;BAX;DDIT3;TRAF2"]
["GO:0009267","cellular response to starvation","biological_process",5,91,69,18684,{"v":2.15598065478809e-05,"d":"2.16E-05"},0.000293306432964336,14.8781653129479,"FOXO1;PPARA;KLF10;SREBF1;MTOR"]
["GO:0008284","positive regulation of cell population proliferation","biological_process",11,91,484,18684,{"v":2.30069883537158e-05,"d":"2.30E-05"},0.000310198514530535,4.66633366633367,"RELA;AKT1;VEGFA;BCL2;IL6;EDN1;MYC;IL1B;BIRC5;IRS1;TGFA"]
["GO:0060326","cell chemotaxis","biological_process",5,91,70,18684,{"v":2.31295560808067e-05,"d":"2.31E-05"},0.000310198514530535,14.6656200941915,"VCAM1;PRKCD;HGF;AGTR1;CCR2"]
["GO:0034976","response to endoplasmic reticulum stress","biological_process",5,91,74,18684,{"v":3.03171374117795e-05,"d":"3.03E-05"},0.000391604812417065,13.8728838728839,"CXCL8;DDIT3;EIF2S1;BCL2L11;TRAF2"]
["GO:0071260","cellular response to mechanical stimulus","biological_process",5,91,74,18684,{"v":3.03171374117795e-05,"d":"3.03E-05"},0.000391604812417065,13.8728838728839,"AKT1;MAPK3;MAPK8;IL1B;TNFRSF10A"]
["GO:0032733","positive regulation of interleukin-10 production","biological_process",4,91,37,18684,{"v":3.07506959072649e-05,"d":"3.08E-05"},0.000391604812417065,22.1966141966142,"STAT3;IL6;HGF;CD28"]
["GO:0046326","positive regulation of glucose import","biological_process",4,91,37,18684,{"v":3.07506959072649e-05,"d":"3.08E-05"},0.000391604812417065,22.1966141966142,"AKT1;NFE2L2;ADIPOR2;IRS1"]
["GO:0019395","fatty acid oxidation","biological_process",3,91,13,18684,{"v":3.08562226600437e-05,"d":"3.09E-05"},0.000391604812417065,47.3812341504649,"PPARG;ADIPOR1;ADIPOR2"]
["GO:0055093","response to hyperoxia","biological_process",3,91,13,18684,{"v":3.08562226600437e-05,"d":"3.09E-05"},0.000391604812417065,47.3812341504649,"CDKN1A;CAT;CYP1A1"]
["GO:0043536","positive regulation of blood vessel endothelial cell migration","biological_process",4,91,38,18684,{"v":3.42408519754764e-05,"d":"3.42E-05"},0.000428804311825336,21.6124927703875,"AKT1;VEGFA;NOS3;NFE2L2"]
["GO:0019722","calcium-mediated signaling","biological_process",5,91,77,18684,{"v":3.67604064515889e-05,"d":"3.68E-05"},0.000454339402614082,13.3323819038105,"EDN1;SELE;CXCL8;AGTR1;CCR2"]
["GO:0007050","cell cycle arrest","biological_process",6,91,128,18684,{"v":3.80530436161322e-05,"d":"3.81E-05"},0.000467261723883805,9.62431318681319,"CDKN1A;MYC;CXCL8;DDIT3;PRKAG2;MTOR"]
["GO:0006978","DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator","biological_process",3,91,14,18684,{"v":3.91330797056778e-05,"d":"3.91E-05"},0.000474363164893825,43.9968602825746,"CDKN1A;BRCA1;BRCA2"]
["GO:0008631","intrinsic apoptotic signaling pathway in response to oxidative stress","biological_process",3,91,14,18684,{"v":3.91330797056778e-05,"d":"3.91E-05"},0.000474363164893825,43.9968602825746,"BCL2;PRKCD;CYP1B1"]
["GO:0007507","heart development","biological_process",7,91,191,18684,{"v":4.09957276190142e-05,"d":"4.10E-05"},0.000493776566417553,7.52476842529199,"CDKN1A;CASP3;EDN1;PPARG;PPARA;ADIPOR2;SPARC"]
["GO:0000165","MAPK cascade","biological_process",8,91,262,18684,{"v":4.18245028567217e-05,"d":"4.18E-05"},0.000497325350627305,6.2692727120208,"MAPK3;MAPK1;MYC;IL1B;HGF;JAK1;IRS1;TGFA"]
["GO:1902895","positive regulation of pri-miRNA transcription by RNA polymerase II","biological_process",4,91,40,18684,{"v":4.20793527765039e-05,"d":"4.21E-05"},0.000497325350627305,20.5318681318681,"RELA;STAT3;IL10;PPARG"]
["GO:0032570","response to progesterone","biological_process",4,91,41,18684,{"v":4.64554516053517e-05,"d":"4.65E-05"},0.00054226703077605,20.0310908603592,"NCOA2;RELA;SREBF1;NR1H3"]
["GO:0008637","apoptotic mitochondrial changes","biological_process",3,91,15,18684,{"v":4.87438983394379e-05,"d":"4.87E-05"},0.000555269347951067,41.0637362637363,"AKT1;BCL2L1;BAX"]
["GO:0035729","cellular response to hepatocyte growth factor stimulus","biological_process",3,91,15,18684,{"v":4.87438983394379e-05,"d":"4.87E-05"},0.000555269347951067,41.0637362637363,"RELA;IL10;HGF"]
["GO:0060252","positive regulation of glial cell proliferation","biological_process",3,91,15,18684,{"v":4.87438983394379e-05,"d":"4.87E-05"},0.000555269347951067,41.0637362637363,"IL6;IL1B;MTOR"]
["GO:0071732","cellular response to nitric oxide","biological_process",3,91,15,18684,{"v":4.87438983394379e-05,"d":"4.87E-05"},0.000555269347951067,41.0637362637363,"FOXO1;CFLAR;TRAF2"]
["GO:0008286","insulin receptor signaling pathway","biological_process",5,91,83,18684,{"v":5.2794450903078e-05,"d":"5.28E-05"},0.000597810219507309,12.3685952601615,"AKT1;FOXO1;PTPN1;SREBF1;IRS1"]
["GO:0010718","positive regulation of epithelial to mesenchymal transition","biological_process",4,91,43,18684,{"v":5.61924287439303e-05,"d":"5.62E-05"},0.000625058133851601,19.0994122156913,"IL6;CTNNB1;IL1B;MTOR"]
["GO:0045454","cell redox homeostasis","biological_process",4,91,43,18684,{"v":5.61924287439303e-05,"d":"5.62E-05"},0.000625058133851601,19.0994122156913,"NOS3;DDIT3;MPO;NFE2L2"]
["GO:0048538","thymus development","biological_process",4,91,43,18684,{"v":5.61924287439303e-05,"d":"5.62E-05"},0.000625058133851601,19.0994122156913,"BCL2;MAPK3;MAPK1;BCL2L11"]
["GO:0006809","nitric oxide biosynthetic process","biological_process",3,91,16,18684,{"v":5.97810323604948e-05,"d":"5.98E-05"},0.000657243791823812,38.4972527472527,"AKT1;NOS3;CYP1B1"]
["GO:0035994","response to muscle stretch","biological_process",3,91,16,18684,{"v":5.97810323604948e-05,"d":"5.98E-05"},0.000657243791823812,38.4972527472527,"RELA;NFKBIA;EDN1"]
["GO:0016525","negative regulation of angiogenesis","biological_process",5,91,87,18684,{"v":6.61678059427019e-05,"d":"6.62E-05"},0.000714990405929425,11.7999242137173,"STAT1;PPARG;CTNNB1;CCR2;SPARC"]
["GO:0045892","negative regulation of transcription, DNA-templated","biological_process",11,91,548,18684,{"v":7.09073157634567e-05,"d":"7.09E-05"},0.000758081187257579,4.12136039143338,"RELA;RUNX1T1;FOXO1;PPARG;CTNNB1;BRCA1;XRCC6;BIRC5;DDIT3;AHR;KLF10"]
["GO:0035066","positive regulation of histone acetylation","biological_process",3,91,17,18684,{"v":7.23354386852207e-05,"d":"7.23E-05"},0.000758081187257579,36.2327084680026,"MAPK3;IL1B;BRCA1"]
["GO:0046889","positive regulation of lipid biosynthetic process","biological_process",3,91,17,18684,{"v":7.23354386852207e-05,"d":"7.23E-05"},0.000758081187257579,36.2327084680026,"AKT1;PPARA;MTOR"]
["GO:0070542","response to fatty acid","biological_process",3,91,17,18684,{"v":7.23354386852207e-05,"d":"7.23E-05"},0.000758081187257579,36.2327084680026,"CAT;FOXO1;PON1"]
["GO:0090201","negative regulation of release of cytochrome c from mitochondria","biological_process",3,91,17,18684,{"v":7.23354386852207e-05,"d":"7.23E-05"},0.000758081187257579,36.2327084680026,"AKT1;BCL2L1;HGF"]
["GO:0009755","hormone-mediated signaling pathway","biological_process",4,91,46,18684,{"v":7.34795484254908e-05,"d":"7.35E-05"},0.000758081187257579,17.8537983755375,"PPARG;PPARA;ADIPOR1;ADIPOR2"]
["GO:0045599","negative regulation of fat cell differentiation","biological_process",4,91,46,18684,{"v":7.34795484254908e-05,"d":"7.35E-05"},0.000758081187257579,17.8537983755375,"IL6;RUNX1T1;FOXO1;DDIT3"]
["GO:0051898","negative regulation of protein kinase B signaling","biological_process",4,91,46,18684,{"v":7.34795484254908e-05,"d":"7.35E-05"},0.000758081187257579,17.8537983755375,"AKT1;XDH;DDIT3;PPARA"]
["GO:0032355","response to estradiol","biological_process",5,91,89,18684,{"v":7.37635845877284e-05,"d":"7.38E-05"},0.000758081187257579,11.534757377454,"STAT3;CCND1;CASP3;CAT;CTNNB1"]
["GO:0019216","regulation of lipid metabolic process","biological_process",5,91,91,18684,{"v":8.20141915346433e-05,"d":"8.20E-05"},0.000838318033470327,11.2812462263012,"NCOA2;PPARG;CYP1A1;PPARA;ADIPOR1"]
["GO:0033189","response to vitamin A","biological_process",3,91,18,18684,{"v":8.64966906515086e-05,"d":"8.65E-05"},0.000870027883095759,34.2197802197802,"CAT;PPARG;CYP1A1"]
["GO:0030968","endoplasmic reticulum unfolded protein response","biological_process",4,91,48,18684,{"v":8.69676881728191e-05,"d":"8.70E-05"},0.00087013702822646,17.1098901098901,"CCND1;PTPN1;DDIT3;NFE2L2"]
["GO:0070498","interleukin-1-mediated signaling pathway","biological_process",5,91,95,18684,0.00010063272231317,0.000996316638189549,10.8062463851938,"RELA;MAPK3;NFKBIA;IL1B;IL1A"]
["GO:0002053","positive regulation of mesenchymal cell proliferation","biological_process",3,91,19,18684,0.000102352991219836,0.00100284718340265,32.4187391555813,"VEGFA;STAT1;MYC"]
["GO:1904706","negative regulation of vascular associated smooth muscle cell proliferation","biological_process",3,91,19,18684,0.000102352991219836,0.00100284718340265,32.4187391555813,"CDKN1A;IL10;PPARG"]
["GO:0006979","response to oxidative stress","biological_process",5,91,98,18684,0.000116605547151352,0.00113660355496498,10.4754429244225,"PTGS1;PTGS2;AKT1;MAPK8;MPO"]
["GO:0009612","response to mechanical stimulus","biological_process",4,91,52,18684,0.000119216772392769,0.00114021775307413,15.7937447168216,"MAPK8;PPARG;CCNB1;MPO"]
["GO:0031295","T cell costimulation","biological_process",4,91,52,18684,0.000119216772392769,0.00114021775307413,15.7937447168216,"AKT1;CD80;CDC42;CD28"]
["GO:0046697","decidualization","biological_process",3,91,20,18684,0.000119991186071789,0.00114021775307413,30.7978021978022,"MAPK3;MAPK1;BSG"]
["GO:0010875","positive regulation of cholesterol efflux","biological_process",3,91,21,18684,0.000139496776606738,0.00130588319090763,29.331240188383,"NFKBIA;PON1;NR1H3"]
["GO:1903672","positive regulation of sprouting angiogenesis","biological_process",3,91,21,18684,0.000139496776606738,0.00130588319090763,29.331240188383,"VEGFA;IL10;JAK1"]
["GO:0030168","platelet activation","biological_process",5,91,102,18684,0.000140846942048698,0.00131202742568516,10.0646412411118,"MAPK3;MAPK1;IL6;PRKCD;PRKCB"]
["GO:0000079","regulation of cyclin-dependent protein serine/threonine kinase activity","biological_process",4,91,55,18684,0.000148524259366199,0.00137676163951707,14.9322677322677,"CCND1;CDKN1A;CCNB1;CCNE1"]
["GO:0051897","positive regulation of protein kinase B signaling","biological_process",6,91,164,18684,0.000150278338794755,0.0013862260422482,7.51165907263468,"HGF;CD80;IRS1;MTOR;CD28;TGFA"]
["GO:0010468","regulation of gene expression","biological_process",7,91,236,18684,0.000154333426271202,0.00141672091785846,6.08996088657106,"BCL2;MAPK3;MAPK1;IL10;MAPK8;MYC;AHR"]
["GO:0001836","release of cytochrome c from mitochondria","biological_process",3,91,22,18684,0.00016095393283739,0.00144935184283573,27.998001998002,"BCL2;BCL2L1;BAX"]
["GO:0007569","cell aging","biological_process",3,91,22,18684,0.00016095393283739,0.00144935184283573,27.998001998002,"BCL2;MTOR;BRCA2"]
["GO:0030225","macrophage differentiation","biological_process",3,91,22,18684,0.00016095393283739,0.00144935184283573,27.998001998002,"VEGFA;MMP9;CDC42"]
["GO:2001243","negative regulation of intrinsic apoptotic signaling pathway","biological_process",3,91,22,18684,0.00016095393283739,0.00144935184283573,27.998001998002,"BCL2;BCL2L1;MMP9"]
["GO:0007611","learning or memory","biological_process",4,91,58,18684,0.00018271786768742,0.00161457704577996,14.1599090564608,"MAPK1;CASP3;SLC2A4;NTRK1"]
["GO:0043627","response to estrogen","biological_process",4,91,58,18684,0.00018271786768742,0.00161457704577996,14.1599090564608,"CCND1;MAPK1;PPARG;BRCA1"]
["GO:0031018","endocrine pancreas development","biological_process",3,91,23,18684,0.000184445506184883,0.00161475209349822,26.7806975633063,"AKT1;IL6;FOXO1"]
["GO:0044772","mitotic cell cycle phase transition","biological_process",3,91,23,18684,0.000184445506184883,0.00161475209349822,26.7806975633063,"CCND1;CCNB1;CCNE1"]
["GO:0035690","cellular response to drug","biological_process",4,91,60,18684,0.00020845469547834,0.00181653377488268,13.6879120879121,"EDN1;MYC;IL1B;NFE2L2"]
["GO:0006508","proteolysis","biological_process",9,91,421,18684,0.000210791083340501,0.00182846760824261,4.38923546762027,"CASP9;PLAU;MMP2;MMP9;CASP3;HGF;PLAT;CFLAR;PAPPA"]
["GO:0010595","positive regulation of endothelial cell migration","biological_process",4,91,61,18684,0.000222257289085289,0.0018621040664892,13.4635200864709,"AKT1;VEGFA;EDN1;SPARC"]
["GO:0003100","regulation of systemic arterial blood pressure by endothelin","biological_process",2,91,5,18684,0.000232393738599392,0.0018621040664892,82.1274725274725,"EDN1;NOS3"]
["GO:0010829","negative regulation of glucose transmembrane transport","biological_process",2,91,5,18684,0.000232393738599392,0.0018621040664892,82.1274725274725,"IL1B;PRKCB"]
["GO:0010891","negative regulation of sequestering of triglyceride","biological_process",2,91,5,18684,0.000232393738599392,0.0018621040664892,82.1274725274725,"PPARG;PPARA"]
["GO:0014042","positive regulation of neuron maturation","biological_process",2,91,5,18684,0.000232393738599392,0.0018621040664892,82.1274725274725,"BCL2;MTOR"]
["GO:0031622","positive regulation of fever generation","biological_process",2,91,5,18684,0.000232393738599392,0.0018621040664892,82.1274725274725,"PTGS2;IL1B"]
["GO:0033591","response to L-ascorbic acid","biological_process",2,91,5,18684,0.000232393738599392,0.0018621040664892,82.1274725274725,"CAT;SPARC"]
["GO:0035696","monocyte extravasation","biological_process",2,91,5,18684,0.000232393738599392,0.0018621040664892,82.1274725274725,"PECAM1;CCR2"]
["GO:0045923","positive regulation of fatty acid metabolic process","biological_process",2,91,5,18684,0.000232393738599392,0.0018621040664892,82.1274725274725,"PPARG;PPARA"]
["GO:0060137","maternal process involved in parturition","biological_process",2,91,5,18684,0.000232393738599392,0.0018621040664892,82.1274725274725,"EDN1;CYP1A1"]
["GO:0060440","trachea formation","biological_process",2,91,5,18684,0.000232393738599392,0.0018621040664892,82.1274725274725,"MAPK3;MAPK1"]
["GO:0070242","thymocyte apoptotic process","biological_process",2,91,5,18684,0.000232393738599392,0.0018621040664892,82.1274725274725,"BAX;BCL2L11"]
["GO:0071681","cellular response to indole-3-methanol","biological_process",2,91,5,18684,0.000232393738599392,0.0018621040664892,82.1274725274725,"CTNNB1;BRCA1"]
["GO:0072584","caveolin-mediated endocytosis","biological_process",2,91,5,18684,0.000232393738599392,0.0018621040664892,82.1274725274725,"MAPK3;MAPK1"]
["GO:0072655","establishment of protein localization to mitochondrion","biological_process",2,91,5,18684,0.000232393738599392,0.0018621040664892,82.1274725274725,"AKT1;DDIT3"]
["GO:0120041","positive regulation of macrophage proliferation","biological_process",2,91,5,18684,0.000232393738599392,0.0018621040664892,82.1274725274725,"MAPK3;MAPK1"]
["GO:0030163","protein catabolic process","biological_process",3,91,25,18684,0.000237856793030193,0.00187411331508373,24.6382417582418,"AKT1;MTOR;TRAF2"]
["GO:0043029","T cell homeostasis","biological_process",3,91,25,18684,0.000237856793030193,0.00187411331508373,24.6382417582418,"BCL2;CASP3;BCL2L11"]
["GO:0048873","homeostasis of number of cells within a tissue","biological_process",3,91,25,18684,0.000237856793030193,0.00187411331508373,24.6382417582418,"BCL2;BAX;NOS3"]
["GO:0097190","apoptotic signaling pathway","biological_process",4,91,63,18684,0.000251818443568332,0.00197588662567517,13.0361067503925,"BAX;CASP3;CFLAR;CD28"]
["GO:0007249","I-kappaB kinase/NF-kappaB signaling","biological_process",4,91,64,18684,0.000267612377743483,0.00205961977952376,12.8324175824176,"RELA;AKT1;NFKBIA;TRAF2"]
["GO:0007584","response to nutrient","biological_process",4,91,64,18684,0.000267612377743483,0.00205961977952376,12.8324175824176,"PPARG;VCAM1;ADIPOR2;MTOR"]
["GO:0046677","response to antibiotic","biological_process",3,91,26,18684,0.000267935730176015,0.00205961977952376,23.6906170752325,"CASP3;CYP1A1;JAK1"]
["GO:0051403","stress-activated MAPK cascade","biological_process",3,91,26,18684,0.000267935730176015,0.00205961977952376,23.6906170752325,"MAPK3;MAPK1;MAPK8"]
["GO:1900745","positive regulation of p38MAPK cascade","biological_process",3,91,26,18684,0.000267935730176015,0.00205961977952376,23.6906170752325,"VEGFA;XDH;IL1B"]
["GO:0030308","negative regulation of cell growth","biological_process",5,91,120,18684,0.00030087783541957,0.00229419349507422,8.55494505494505,"BCL2;CDKN1A;PPARG;ADIPOR1;ADIPOR2"]
["GO:0008217","regulation of blood pressure","biological_process",4,91,67,18684,0.000319261984114611,0.0024245960319708,12.2578317205183,"PTGS1;PTGS2;PPARG;NOS3"]
["GO:0001569","branching involved in blood vessel morphogenesis","biological_process",3,91,28,18684,0.000335228719323208,0.00251554566761979,21.9984301412873,"VEGFA;EDN1;CTNNB1"]
["GO:0045737","positive regulation of cyclin-dependent protein serine/threonine kinase activity","biological_process",3,91,28,18684,0.000335228719323208,0.00251554566761979,21.9984301412873,"AKT1;CCND1;CCNB1"]
["GO:0051090","regulation of DNA-binding transcription factor activity","biological_process",3,91,28,18684,0.000335228719323208,0.00251554566761979,21.9984301412873,"MAPK3;MAPK1;MAPK8"]
["GO:0001844","protein insertion into mitochondrial membrane involved in apoptotic signaling pathway","biological_process",2,91,6,18684,0.000347484687870826,0.00253704071337348,68.4395604395605,"BAX;BCL2L11"]
["GO:0035234","ectopic germ cell programmed cell death","biological_process",2,91,6,18684,0.000347484687870826,0.00253704071337348,68.4395604395605,"BAX;IL1A"]
["GO:0042473","outer ear morphogenesis","biological_process",2,91,6,18684,0.000347484687870826,0.00253704071337348,68.4395604395605,"MAPK3;MAPK1"]
["GO:0046321","positive regulation of fatty acid oxidation","biological_process",2,91,6,18684,0.000347484687870826,0.00253704071337348,68.4395604395605,"PPARG;PPARA"]
["GO:0061419","positive regulation of transcription from RNA polymerase II promoter in response to hypoxia","biological_process",2,91,6,18684,0.000347484687870826,0.00253704071337348,68.4395604395605,"VEGFA;NFE2L2"]
["GO:1903038","negative regulation of leukocyte cell-cell adhesion","biological_process",2,91,6,18684,0.000347484687870826,0.00253704071337348,68.4395604395605,"AKT1;PPARA"]
["GO:1903721","positive regulation of I-kappaB phosphorylation","biological_process",2,91,6,18684,0.000347484687870826,0.00253704071337348,68.4395604395605,"AKT1;TRAF2"]
["GO:0000187","activation of MAPK activity","biological_process",5,91,124,18684,0.000350079315201287,0.00254615378863705,8.2789790854307,"MAPK3;MAPK1;IL1B;HGF;TGFA"]
["GO:0007159","leukocyte cell-cell adhesion","biological_process",3,91,29,18684,0.000372594421277998,0.00265877754957243,21.2398635846912,"SELE;VCAM1;PECAM1"]
["GO:0051881","regulation of mitochondrial membrane potential","biological_process",3,91,29,18684,0.000372594421277998,0.00265877754957243,21.2398635846912,"BCL2;BCL2L1;BAX"]
["GO:0070371","ERK1 and ERK2 cascade","biological_process",3,91,29,18684,0.000372594421277998,0.00265877754957243,21.2398635846912,"MAPK3;MAPK1;MYC"]
["GO:0001938","positive regulation of endothelial cell proliferation","biological_process",4,91,70,18684,0.000377692836161525,0.00267497061116646,11.7324960753532,"AKT1;VEGFA;IL10;MTOR"]
["GO:0060333","interferon-gamma-mediated signaling pathway","biological_process",4,91,70,18684,0.000377692836161525,0.00267497061116646,11.7324960753532,"STAT1;VCAM1;PRKCD;JAK1"]
["GO:0038096","Fc-gamma receptor signaling pathway involved in phagocytosis","biological_process",4,91,71,18684,0.00039876185623807,0.00281365175427683,11.5672496517567,"MAPK3;MAPK1;PRKCD;CDC42"]
["GO:0001937","negative regulation of endothelial cell proliferation","biological_process",3,91,30,18684,0.000412538633747385,0.00285754782570075,20.5318681318681,"XDH;STAT1;SPARC"]
["GO:0008625","extrinsic apoptotic signaling pathway via death domain receptors","biological_process",3,91,30,18684,0.000412538633747385,0.00285754782570075,20.5318681318681,"BCL2;BAX;TNFRSF10A"]
["GO:0038111","interleukin-7-mediated signaling pathway","biological_process",3,91,30,18684,0.000412538633747385,0.00285754782570075,20.5318681318681,"STAT3;JAK1;IRS1"]
["GO:0043542","endothelial cell migration","biological_process",3,91,30,18684,0.000412538633747385,0.00285754782570075,20.5318681318681,"STAT1;NOS3;CYP1B1"]
["GO:1900087","positive regulation of G1/S transition of mitotic cell cycle","biological_process",3,91,30,18684,0.000412538633747385,0.00285754782570075,20.5318681318681,"AKT1;CCND1;CYP1A1"]
["GO:0016241","regulation of macroautophagy","biological_process",4,91,72,18684,0.000420657567396309,0.00290315131367306,11.4065934065934,"CASP3;MAPK8;PRKAG2;MTOR"]
["GO:0006606","protein import into nucleus","biological_process",4,91,73,18684,0.000443398466631379,0.00303792210289833,11.2503387023935,"STAT3;AKT1;CDKN1A;NFKBIA"]
["GO:0050900","leukocyte migration","biological_process",5,91,131,18684,0.000450553261276459,0.00304119646161993,7.836590890026,"MMP9;SELE;PECAM1;TNFRSF10A;BSG"]
["GO:0007259","receptor signaling pathway via JAK-STAT","biological_process",3,91,31,18684,0.00045513410821705,0.00304119646161993,19.8695498050337,"STAT3;STAT1;CCR2"]
["GO:0007281","germ cell development","biological_process",3,91,31,18684,0.00045513410821705,0.00304119646161993,19.8695498050337,"AKT1;BAX;MTOR"]
["GO:0097421","liver regeneration","biological_process",3,91,31,18684,0.00045513410821705,0.00304119646161993,19.8695498050337,"CCND1;IL10;IL6"]
["GO:0008635","activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c","biological_process",2,91,7,18684,0.000484935741902735,0.00305671162646024,58.6624803767661,"BAX;CASP9"]
["GO:0010573","vascular endothelial growth factor production","biological_process",2,91,7,18684,0.000484935741902735,0.00305671162646024,58.6624803767661,"IL6;IL1B"]
["GO:0010742","macrophage derived foam cell differentiation","biological_process",2,91,7,18684,0.000484935741902735,0.00305671162646024,58.6624803767661,"STAT1;PPARG"]
["GO:0014909","smooth muscle cell migration","biological_process",2,91,7,18684,0.000484935741902735,0.00305671162646024,58.6624803767661,"PLAU;PLAT"]
["GO:0030641","regulation of cellular pH","biological_process",2,91,7,18684,0.000484935741902735,0.00305671162646024,58.6624803767661,"MAPK3;MAPK1"]
["GO:0031394","positive regulation of prostaglandin biosynthetic process","biological_process",2,91,7,18684,0.000484935741902735,0.00305671162646024,58.6624803767661,"PTGS2;IL1B"]
["GO:0033211","adiponectin-activated signaling pathway","biological_process",2,91,7,18684,0.000484935741902735,0.00305671162646024,58.6624803767661,"ADIPOR1;ADIPOR2"]
["GO:0033598","mammary gland epithelial cell proliferation","biological_process",2,91,7,18684,0.000484935741902735,0.00305671162646024,58.6624803767661,"CCND1;MAPK1"]
["GO:0034351","negative regulation of glial cell apoptotic process","biological_process",2,91,7,18684,0.000484935741902735,0.00305671162646024,58.6624803767661,"PRKCD;TRAF2"]
["GO:0060020","Bergmann glial cell differentiation","biological_process",2,91,7,18684,0.000484935741902735,0.00305671162646024,58.6624803767661,"MAPK3;MAPK1"]
["GO:0060336","negative regulation of interferon-gamma-mediated signaling pathway","biological_process",2,91,7,18684,0.000484935741902735,0.00305671162646024,58.6624803767661,"PPARG;NR1H3"]
["GO:0071455","cellular response to hyperoxia","biological_process",2,91,7,18684,0.000484935741902735,0.00305671162646024,58.6624803767661,"FOXO1;PPARG"]
["GO:0072540","T-helper 17 cell lineage commitment","biological_process",2,91,7,18684,0.000484935741902735,0.00305671162646024,58.6624803767661,"STAT3;IL6"]
["GO:0150078","positive regulation of neuroinflammatory response","biological_process",2,91,7,18684,0.000484935741902735,0.00305671162646024,58.6624803767661,"IL6;IL1B"]
["GO:0070555","response to interleukin-1","biological_process",3,91,32,18684,0.000500452388329907,0.00314403809412576,19.2486263736264,"RELA;IL1B;SELE"]
["GO:0043330","response to exogenous dsRNA","biological_process",3,91,33,18684,0.000548563821714142,0.00340109569462768,18.6653346653347,"MAPK3;MAPK1;NFKBIA"]
["GO:0051973","positive regulation of telomerase activity","biological_process",3,91,33,18684,0.000548563821714142,0.00340109569462768,18.6653346653347,"MAPK3;MAPK1;MYC"]
["GO:0098869","cellular oxidant detoxification","biological_process",4,91,79,18684,0.000598636092776719,0.00366901471883193,10.3958825984142,"PTGS1;PTGS2;CAT;PTGES"]
["GO:0001974","blood vessel remodeling","biological_process",3,91,34,18684,0.000599537571718174,0.00366901471883193,18.1163542340013,"BAX;NOS3;CCR2"]
["GO:0042100","B cell proliferation","biological_process",3,91,34,18684,0.000599537571718174,0.00366901471883193,18.1163542340013,"BCL2;IL10;PRKCD"]
["GO:0045787","positive regulation of cell cycle","biological_process",3,91,34,18684,0.000599537571718174,0.00366901471883193,18.1163542340013,"CCND1;IL10;BCL2L11"]
["GO:0031647","regulation of protein stability","biological_process",4,91,80,18684,0.000627816026970571,0.00373867612537091,10.2659340659341,"BCL2;MAPK1;CASP3;SREBF1"]
["GO:0032088","negative regulation of NF-kappaB transcription factor activity","biological_process",4,91,80,18684,0.000627816026970571,0.00373867612537091,10.2659340659341,"NFKBIA;CAT;CYP1B1;DDIT3"]
["GO:0001783","B cell apoptotic process","biological_process",2,91,8,18684,0.000644531156462674,0.00373867612537091,51.3296703296703,"BAX;BCL2L11"]
["GO:0001955","blood vessel maturation","biological_process",2,91,8,18684,0.000644531156462674,0.00373867612537091,51.3296703296703,"MMP2;DDIT3"]
["GO:0002237","response to molecule of bacterial origin","biological_process",2,91,8,18684,0.000644531156462674,0.00373867612537091,51.3296703296703,"IL10;CXCL8"]
["GO:0007253","cytoplasmic sequestering of NF-kappaB","biological_process",2,91,8,18684,0.000644531156462674,0.00373867612537091,51.3296703296703,"IL10;NFKBIA"]
["GO:0009308","amine metabolic process","biological_process",2,91,8,18684,0.000644531156462674,0.00373867612537091,51.3296703296703,"CYP1A1;VCAM1"]
["GO:0010224","response to UV-B","biological_process",2,91,8,18684,0.000644531156462674,0.00373867612537091,51.3296703296703,"RELA;BCL2"]
["GO:0010827","regulation of glucose transmembrane transport","biological_process",2,91,8,18684,0.000644531156462674,0.00373867612537091,51.3296703296703,"EDN1;PRKCB"]
["GO:0032873","negative regulation of stress-activated MAPK cascade","biological_process",2,91,8,18684,0.000644531156462674,0.00373867612537091,51.3296703296703,"FOXO1;MYC"]
["GO:0033210","leptin-mediated signaling pathway","biological_process",2,91,8,18684,0.000644531156462674,0.00373867612537091,51.3296703296703,"STAT3;ADIPOR1"]
["GO:0034405","response to fluid shear stress","biological_process",2,91,8,18684,0.000644531156462674,0.00373867612537091,51.3296703296703,"AKT1;NOS3"]
["GO:0061042","vascular wound healing","biological_process",2,91,8,18684,0.000644531156462674,0.00373867612537091,51.3296703296703,"VEGFA;ADIPOR2"]
["GO:0061051","positive regulation of cell growth involved in cardiac muscle cell development","biological_process",2,91,8,18684,0.000644531156462674,0.00373867612537091,51.3296703296703,"EDN1;MTOR"]
["GO:0070431","nucleotide-binding oligomerization domain containing 2 signaling pathway","biological_process",2,91,8,18684,0.000644531156462674,0.00373867612537091,51.3296703296703,"RELA;NFKBIA"]
["GO:2000641","regulation of early endosome to late endosome transport","biological_process",2,91,8,18684,0.000644531156462674,0.00373867612537091,51.3296703296703,"MAPK3;MAPK1"]
["GO:0050729","positive regulation of inflammatory response","biological_process",4,91,81,18684,0.000657991067750383,0.00378194865992697,10.1391941391941,"NFKBIA;IL1B;AGTR1;CCR2"]
["GO:0071392","cellular response to estradiol stimulus","biological_process",3,91,36,18684,0.00071034282334397,0.00407047963316196,17.1098901098901,"IL10;CFLAR;BCL2L11"]
["GO:0032755","positive regulation of interleukin-6 production","biological_process",4,91,83,18684,0.000721402201075401,0.00409661129799875,9.89487620812922,"STAT3;IL6;IL1B;IL1A"]
["GO:0032760","positive regulation of tumor necrosis factor production","biological_process",4,91,83,18684,0.000721402201075401,0.00409661129799875,9.89487620812922,"STAT3;IL6;IL1A;CCR2"]
["GO:0014065","phosphatidylinositol 3-kinase signaling","biological_process",3,91,37,18684,0.000770306834588385,0.00436122821618753,16.6474606474606,"AKT1;EDN1;IRS1"]
["GO:0048013","ephrin receptor signaling pathway","biological_process",4,91,85,18684,0.00078902122752844,0.00445185312079058,9.66205559146736,"MMP2;MMP9;NTRK1;CDC42"]
["GO:0002544","chronic inflammatory response","biological_process",2,91,9,18684,0.00082605671840164,0.00445185312079058,45.6263736263736,"VCAM1;PTGES"]
["GO:0032872","regulation of stress-activated MAPK cascade","biological_process",2,91,9,18684,0.00082605671840164,0.00445185312079058,45.6263736263736,"MAPK3;MAPK1"]
["GO:0033197","response to vitamin E","biological_process",2,91,9,18684,0.00082605671840164,0.00445185312079058,45.6263736263736,"CCND1;CAT"]
["GO:0035148","tube formation","biological_process",2,91,9,18684,0.00082605671840164,0.00445185312079058,45.6263736263736,"VEGFA;BCL2L11"]
["GO:0043583","ear development","biological_process",2,91,9,18684,0.00082605671840164,0.00445185312079058,45.6263736263736,"BCL2;BCL2L11"]
["GO:0046641","positive regulation of alpha-beta T cell proliferation","biological_process",2,91,9,18684,0.00082605671840164,0.00445185312079058,45.6263736263736,"CCR2;CD28"]
["GO:0046902","regulation of mitochondrial membrane permeability","biological_process",2,91,9,18684,0.00082605671840164,0.00445185312079058,45.6263736263736,"BCL2;BCL2L1"]
["GO:0048660","regulation of smooth muscle cell proliferation","biological_process",2,91,9,18684,0.00082605671840164,0.00445185312079058,45.6263736263736,"CTNNB1;XRCC6"]
["GO:0070417","cellular response to cold","biological_process",2,91,9,18684,0.00082605671840164,0.00445185312079058,45.6263736263736,"NFKBIA;FOXO1"]
["GO:0071316","cellular response to nicotine","biological_process",2,91,9,18684,0.00082605671840164,0.00445185312079058,45.6263736263736,"RELA;NTRK1"]
["GO:0097011","cellular response to granulocyte macrophage colony-stimulating factor stimulus","biological_process",2,91,9,18684,0.00082605671840164,0.00445185312079058,45.6263736263736,"AKT1;MAPK1"]
["GO:1903589","positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis","biological_process",2,91,9,18684,0.00082605671840164,0.00445185312079058,45.6263736263736,"VEGFA;AGTR1"]
["GO:0001541","ovarian follicle development","biological_process",3,91,38,18684,0.000833398204526635,0.00445185312079058,16.2093695777906,"VEGFA;BCL2;BAX"]
["GO:0050853","B cell receptor signaling pathway","biological_process",3,91,38,18684,0.000833398204526635,0.00445185312079058,16.2093695777906,"BCL2;MAPK1;PRKCB"]
["GO:0051402","neuron apoptotic process","biological_process",3,91,38,18684,0.000833398204526635,0.00445185312079058,16.2093695777906,"BCL2;BAX;CASP3"]
["GO:1904646","cellular response to amyloid-beta","biological_process",3,91,38,18684,0.000833398204526635,0.00445185312079058,16.2093695777906,"VCAM1;NTRK1;BCL2L11"]
["GO:0014068","positive regulation of phosphatidylinositol 3-kinase signaling","biological_process",4,91,88,18684,0.000898672336465155,0.00476553371965686,9.33266733266733,"CAT;HGF;NTRK1;CD28"]
["GO:0033138","positive regulation of peptidyl-serine phosphorylation","biological_process",4,91,88,18684,0.000898672336465155,0.00476553371965686,9.33266733266733,"AKT1;VEGFA;BCL2;IL6"]
["GO:0043407","negative regulation of MAP kinase activity","biological_process",3,91,39,18684,0.000899680347920412,0.00476553371965686,15.7937447168216,"IL1B;PRKCD;PTPN1"]
["GO:0030890","positive regulation of B cell proliferation","biological_process",3,91,40,18684,0.000969215563742891,0.00511951572915589,15.3989010989011,"BCL2;CDKN1A;CD320"]
["GO:0002262","myeloid cell homeostasis","biological_process",2,91,10,18684,0.00102929973612439,0.00527481246886509,41.0637362637363,"BAX;BCL2L11"]
["GO:0010907","positive regulation of glucose metabolic process","biological_process",2,91,10,18684,0.00102929973612439,0.00527481246886509,41.0637362637363,"AKT1;IRS1"]
["GO:0031639","plasminogen activation","biological_process",2,91,10,18684,0.00102929973612439,0.00527481246886509,41.0637362637363,"PLAU;PLAT"]
["GO:0032000","positive regulation of fatty acid beta-oxidation","biological_process",2,91,10,18684,0.00102929973612439,0.00527481246886509,41.0637362637363,"PPARA;IRS1"]
["GO:0032966","negative regulation of collagen biosynthetic process","biological_process",2,91,10,18684,0.00102929973612439,0.00527481246886509,41.0637362637363,"IL6;PPARG"]
["GO:0043068","positive regulation of programmed cell death","biological_process",2,91,10,18684,0.00102929973612439,0.00527481246886509,41.0637362637363,"CDKN1A;NTRK1"]
["GO:0045792","negative regulation of cell size","biological_process",2,91,10,18684,0.00102929973612439,0.00527481246886509,41.0637362637363,"AKT1;MTOR"]
["GO:0097267","omega-hydroxylase P450 pathway","biological_process",2,91,10,18684,0.00102929973612439,0.00527481246886509,41.0637362637363,"CYP1A1;CYP1B1"]
["GO:1902237","positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway","biological_process",2,91,10,18684,0.00102929973612439,0.00527481246886509,41.0637362637363,"DDIT3;BCL2L11"]
["GO:0031100","animal organ regeneration","biological_process",3,91,41,18684,0.00104206504628006,0.00532579730409621,15.0233181452694,"CDKN1A;PPARG;HGF"]
["GO:0000186","activation of MAPKK activity","biological_process",3,91,42,18684,0.00111828889614406,0.00566939491315931,14.6656200941915,"MAPK3;MAPK1;NTRK1"]
["GO:0007595","lactation","biological_process",3,91,42,18684,0.00111828889614406,0.00566939491315931,14.6656200941915,"VEGFA;CCND1;XDH"]
["GO:0031667","response to nutrient levels","biological_process",3,91,42,18684,0.00111828889614406,0.00566939491315931,14.6656200941915,"PON1;NTRK1;MTOR"]
["GO:0048146","positive regulation of fibroblast proliferation","biological_process",3,91,43,18684,0.00119794613119907,0.00604084302425986,14.3245591617685,"CDKN1A;MYC;CCNB1"]
["GO:0030212","hyaluronan metabolic process","biological_process",2,91,11,18684,0.00125404903011468,0.00615949796349834,37.3306693306693,"AKT1;HGF"]
["GO:0033234","negative regulation of protein sumoylation","biological_process",2,91,11,18684,0.00125404903011468,0.00615949796349834,37.3306693306693,"RELA;CTNNB1"]
["GO:0033993","response to lipid","biological_process",2,91,11,18684,0.00125404903011468,0.00615949796349834,37.3306693306693,"PPARG;PPARA"]
["GO:0042953","lipoprotein transport","biological_process",2,91,11,18684,0.00125404903011468,0.00615949796349834,37.3306693306693,"PPARG;PRKCB"]
["GO:0043276","anoikis","biological_process",2,91,11,18684,0.00125404903011468,0.00615949796349834,37.3306693306693,"AKT1;MTOR"]
["GO:0046685","response to arsenic-containing substance","biological_process",2,91,11,18684,0.00125404903011468,0.00615949796349834,37.3306693306693,"CDKN1A;CYP1A1"]
["GO:0070166","enamel mineralization","biological_process",2,91,11,18684,0.00125404903011468,0.00615949796349834,37.3306693306693,"FOXO1;PPARA"]
["GO:0071492","cellular response to UV-A","biological_process",2,91,11,18684,0.00125404903011468,0.00615949796349834,37.3306693306693,"MMP2;MMP9"]
["GO:1903427","negative regulation of reactive oxygen species biosynthetic process","biological_process",2,91,11,18684,0.00125404903011468,0.00615949796349834,37.3306693306693,"PPARA;CFLAR"]
["GO:0034599","cellular response to oxidative stress","biological_process",4,91,97,18684,0.00129162986700194,0.00627884853085004,8.46674974510026,"CAT;FOXO1;NFE2L2;EIF2S1"]
["GO:0120162","positive regulation of cold-induced thermogenesis","biological_process",4,91,97,18684,0.00129162986700194,0.00627884853085004,8.46674974510026,"VEGFA;ADIPOR1;ADIPOR2;CCR2"]
["GO:0000082","G1/S transition of mitotic cell cycle","biological_process",4,91,98,18684,0.0013416309018892,0.00648855252038995,8.38035433953801,"CCND1;CDKN1A;MYC;CCNE1"]
["GO:0016310","phosphorylation","biological_process",4,91,98,18684,0.0013416309018892,0.00648855252038995,8.38035433953801,"STAT3;AKT1;MAPK3;MTOR"]
["GO:0030198","extracellular matrix organization","biological_process",6,91,251,18684,0.00142399802874517,0.00685185819938199,4.90801628650234,"MMP2;MMP9;VCAM1;PECAM1;BSG;SPARC"]
["GO:0034605","cellular response to heat","biological_process",3,91,46,18684,0.0014580923119515,0.0069868953211014,13.3903487816531,"CDKN1A;IL1A;EIF2S1"]
["GO:0005979","regulation of glycogen biosynthetic process","biological_process",2,91,12,18684,0.00150009492351516,0.0069868953211014,34.2197802197802,"AKT1;MTOR"]
["GO:0007077","mitotic nuclear envelope disassembly","biological_process",2,91,12,18684,0.00150009492351516,0.0069868953211014,34.2197802197802,"PRKCB;CCNB1"]
["GO:0030278","regulation of ossification","biological_process",2,91,12,18684,0.00150009492351516,0.0069868953211014,34.2197802197802,"MAPK3;MAPK1"]
["GO:0030949","positive regulation of vascular endothelial growth factor receptor signaling pathway","biological_process",2,91,12,18684,0.00150009492351516,0.0069868953211014,34.2197802197802,"IL1B;PRKCB"]
["GO:0032495","response to muramyl dipeptide","biological_process",2,91,12,18684,0.00150009492351516,0.0069868953211014,34.2197802197802,"RELA;NFKBIA"]
["GO:0042119","neutrophil activation","biological_process",2,91,12,18684,0.00150009492351516,0.0069868953211014,34.2197802197802,"PRKCD;CXCL8"]
["GO:0048009","insulin-like growth factor receptor signaling pathway","biological_process",2,91,12,18684,0.00150009492351516,0.0069868953211014,34.2197802197802,"AKT1;IRS1"]
["GO:0051549","positive regulation of keratinocyte migration","biological_process",2,91,12,18684,0.00150009492351516,0.0069868953211014,34.2197802197802,"MMP9;MTOR"]
["GO:0060425","lung morphogenesis","biological_process",2,91,12,18684,0.00150009492351516,0.0069868953211014,34.2197802197802,"MAPK3;MAPK1"]
["GO:1904996","positive regulation of leukocyte adhesion to vascular endothelial cell","biological_process",2,91,12,18684,0.00150009492351516,0.0069868953211014,34.2197802197802,"RELA;IL6"]
["GO:2001022","positive regulation of response to DNA damage stimulus","biological_process",2,91,12,18684,0.00150009492351516,0.0069868953211014,34.2197802197802,"MYC;PRKCD"]
["GO:0035722","interleukin-12-mediated signaling pathway","biological_process",3,91,47,18684,0.00155205198901671,0.00717586873161516,13.1054477437456,"IL10;JAK1;CDC42"]
["GO:0042542","response to hydrogen peroxide","biological_process",3,91,47,18684,0.00155205198901671,0.00717586873161516,13.1054477437456,"BCL2;CASP3;CAT"]
["GO:0042149","cellular response to glucose starvation","biological_process",3,91,48,18684,0.00164972427573964,0.00758943356782364,12.8324175824176,"BCL2;NFE2L2;PRKAG2"]
["GO:0001822","kidney development","biological_process",4,91,105,18684,0.00173014882116353,0.00790030846135244,7.82166405023548,"VEGFA;BAX;AGTR1;BCL2L11"]
["GO:0002526","acute inflammatory response","biological_process",2,91,13,18684,0.00176722923276154,0.00790030846135244,31.5874894336433,"VCAM1;PTGES"]
["GO:0010867","positive regulation of triglyceride biosynthetic process","biological_process",2,91,13,18684,0.00176722923276154,0.00790030846135244,31.5874894336433,"SREBF1;NR1H3"]
["GO:0019430","removal of superoxide radicals","biological_process",2,91,13,18684,0.00176722923276154,0.00790030846135244,31.5874894336433,"NOS3;MPO"]
["GO:0032725","positive regulation of granulocyte macrophage colony-stimulating factor production","biological_process",2,91,13,18684,0.00176722923276154,0.00790030846135244,31.5874894336433,"IL1B;CD80"]
["GO:0035723","interleukin-15-mediated signaling pathway","biological_process",2,91,13,18684,0.00176722923276154,0.00790030846135244,31.5874894336433,"STAT3;JAK1"]
["GO:0060334","regulation of interferon-gamma-mediated signaling pathway","biological_process",2,91,13,18684,0.00176722923276154,0.00790030846135244,31.5874894336433,"STAT1;JAK1"]
["GO:1904645","response to amyloid-beta","biological_process",2,91,13,18684,0.00176722923276154,0.00790030846135244,31.5874894336433,"MMP2;MMP9"]
["GO:2000273","positive regulation of signaling receptor activity","biological_process",2,91,13,18684,0.00176722923276154,0.00790030846135244,31.5874894336433,"IL10;EDN1"]
["GO:0043280","positive regulation of cysteine-type endopeptidase activity involved in apoptotic process","biological_process",3,91,50,18684,0.00185641665350431,0.00827944314098266,12.3191208791209,"MYC;BCL2L11;TNFSF10"]
["GO:0043123","positive regulation of I-kappaB kinase/NF-kappaB signaling","biological_process",5,91,182,18684,0.0019634318129951,0.00871560929195712,5.64062311315059,"RELA;PRKCB;CFLAR;TNFSF10;TRAF2"]
["GO:0038095","Fc-epsilon receptor signaling pathway","biological_process",4,91,110,18684,0.00205137104189842,0.00885300406239223,7.46613386613387,"RELA;MAPK3;MAPK1;MAPK8"]
["GO:0010039","response to iron ion","biological_process",2,91,14,18684,0.00205524525827086,0.00885300406239223,29.331240188383,"CCND1;BCL2"]
["GO:0010243","response to organonitrogen compound","biological_process",2,91,14,18684,0.00205524525827086,0.00885300406239223,29.331240188383,"CCND1;CDKN1A"]
["GO:0050930","induction of positive chemotaxis","biological_process",2,91,14,18684,0.00205524525827086,0.00885300406239223,29.331240188383,"VEGFA;CXCL8"]
["GO:0051146","striated muscle cell differentiation","biological_process",2,91,14,18684,0.00205524525827086,0.00885300406239223,29.331240188383,"AKT1;CASP3"]
["GO:0060397","growth hormone receptor signaling pathway via JAK-STAT","biological_process",2,91,14,18684,0.00205524525827086,0.00885300406239223,29.331240188383,"STAT3;PTPN1"]
["GO:0060749","mammary gland alveolus development","biological_process",2,91,14,18684,0.00205524525827086,0.00885300406239223,29.331240188383,"VEGFA;CCND1"]
["GO:1901222","regulation of NIK/NF-kappaB signaling","biological_process",2,91,14,18684,0.00205524525827086,0.00885300406239223,29.331240188383,"RELA;NFKBIA"]
["GO:1902176","negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway","biological_process",2,91,14,18684,0.00205524525827086,0.00885300406239223,29.331240188383,"AKT1;NFE2L2"]
["GO:1902894","negative regulation of pri-miRNA transcription by RNA polymerase II","biological_process",2,91,14,18684,0.00205524525827086,0.00885300406239223,29.331240188383,"RELA;PPARA"]
["GO:2000573","positive regulation of DNA biosynthetic process","biological_process",2,91,14,18684,0.00205524525827086,0.00885300406239223,29.331240188383,"MYC;HGF"]
["GO:0032481","positive regulation of type I interferon production","biological_process",3,91,52,18684,0.00207857937071213,0.00889274567877066,11.8453085376162,"RELA;CTNNB1;XRCC6"]
["GO:0042475","odontogenesis of dentin-containing tooth","biological_process",3,91,52,18684,0.00207857937071213,0.00889274567877066,11.8453085376162,"BAX;BCL2L11;BSG"]
["GO:0006935","chemotaxis","biological_process",4,91,112,18684,0.00219066907126366,0.00928826150110825,7.33281004709576,"PLAU;MAPK1;CXCL8;CCR2"]
["GO:0031334","positive regulation of protein-containing complex assembly","biological_process",3,91,53,18684,0.00219558587572469,0.00928826150110825,11.621812150114,"VEGFA;BAX;BCL2L11"]
["GO:0045860","positive regulation of protein kinase activity","biological_process",3,91,53,18684,0.00219558587572469,0.00928826150110825,11.621812150114,"CDKN1A;XRCC6;PRKAG2"]
["GO:1901215","negative regulation of neuron death","biological_process",3,91,53,18684,0.00219558587572469,0.00928826150110825,11.621812150114,"AKT1;PPARA;TRAF2"]
["GO:0010976","positive regulation of neuron projection development","biological_process",4,91,113,18684,0.002262708350016,0.00955085153991127,7.26791792278518,"NFE2L2;NTRK1;CFLAR;MTOR"]
["GO:0006112","energy reserve metabolic process","biological_process",2,91,15,18684,0.00236393777518338,0.00978163311350497,27.3758241758242,"MYC;MTOR"]
["GO:0010469","regulation of signaling receptor activity","biological_process",2,91,15,18684,0.00236393777518338,0.00978163311350497,27.3758241758242,"PLAU;PRKCD"]
["GO:0016242","negative regulation of macroautophagy","biological_process",2,91,15,18684,0.00236393777518338,0.00978163311350497,27.3758241758242,"AKT1;MTOR"]
["GO:0030224","monocyte differentiation","biological_process",2,91,15,18684,0.00236393777518338,0.00978163311350497,27.3758241758242,"VEGFA;PPARG"]
["GO:0060324","face development","biological_process",2,91,15,18684,0.00236393777518338,0.00978163311350497,27.3758241758242,"MAPK3;MAPK1"]
["GO:0071380","cellular response to prostaglandin E stimulus","biological_process",2,91,15,18684,0.00236393777518338,0.00978163311350497,27.3758241758242,"AKT1;PPARG"]
["GO:1903351","cellular response to dopamine","biological_process",2,91,15,18684,0.00236393777518338,0.00978163311350497,27.3758241758242,"MAPK3;MAPK1"]
["GO:0051592","response to calcium ion","biological_process",3,91,55,18684,0.0024416882102458,0.0100812934619537,11.1992007992008,"CCND1;PTGES;SPARC"]
["GO:0043312","neutrophil degranulation","biological_process",8,91,483,18684,0.00245251223096197,0.0101039229384512,3.40072350010238,"PLAU;MMP9;MAPK1;CAT;PRKCD;XRCC6;PECAM1;MPO"]
["GO:0006977","DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest","biological_process",3,91,56,18684,0.00257087678358983,0.0105685391255834,10.9992150706436,"CDKN1A;BAX;CCNB1"]
["GO:0019372","lipoxygenase pathway","biological_process",2,91,16,18684,0.00269310302415808,0.0109266554738009,25.6648351648352,"PTGS2;PON1"]
["GO:0034116","positive regulation of heterotypic cell-cell adhesion","biological_process",2,91,16,18684,0.00269310302415808,0.0109266554738009,25.6648351648352,"IL10;IL1B"]
["GO:0045725","positive regulation of glycogen biosynthetic process","biological_process",2,91,16,18684,0.00269310302415808,0.0109266554738009,25.6648351648352,"AKT1;IRS1"]
["GO:0051571","positive regulation of histone H3-K4 methylation","biological_process",2,91,16,18684,0.00269310302415808,0.0109266554738009,25.6648351648352,"CTNNB1;BRCA1"]
["GO:0006959","humoral immune response","biological_process",3,91,57,18684,0.00270421721932248,0.0109266554738009,10.8062463851938,"BCL2;IL6;CD28"]
["GO:0050679","positive regulation of epithelial cell proliferation","biological_process",3,91,57,18684,0.00270421721932248,0.0109266554738009,10.8062463851938,"VEGFA;MYC;TGFA"]
["GO:0051607","defense response to virus","biological_process",5,91,200,18684,0.00295363533692841,0.0119090072966559,5.13296703296703,"RELA;BCL2;BCL2L1;IL6;STAT1"]
["GO:0043154","negative regulation of cysteine-type endopeptidase activity involved in apoptotic process","biological_process",3,91,59,18684,0.00298352887921739,0.0119614151474016,10.4399329484075,"AKT1;VEGFA;HGF"]
["GO:0033209","tumor necrosis factor-mediated signaling pathway","biological_process",4,91,122,18684,0.00298605649391429,0.0119614151474016,6.73176004323545,"RELA;NFKBIA;STAT1;TRAF2"]
["GO:0010759","positive regulation of macrophage chemotaxis","biological_process",2,91,17,18684,0.00304253870222112,0.0119614151474016,24.1551389786684,"MAPK3;MAPK1"]
["GO:0019229","regulation of vasoconstriction","biological_process",2,91,17,18684,0.00304253870222112,0.0119614151474016,24.1551389786684,"EDN1;AGTR1"]
["GO:0030889","negative regulation of B cell proliferation","biological_process",2,91,17,18684,0.00304253870222112,0.0119614151474016,24.1551389786684,"IL10;CASP3"]
["GO:0032469","endoplasmic reticulum calcium ion homeostasis","biological_process",2,91,17,18684,0.00304253870222112,0.0119614151474016,24.1551389786684,"BCL2;BAX"]
["GO:0034374","low-density lipoprotein particle remodeling","biological_process",2,91,17,18684,0.00304253870222112,0.0119614151474016,24.1551389786684,"MPO;AGTR1"]
["GO:0042310","vasoconstriction","biological_process",2,91,17,18684,0.00304253870222112,0.0119614151474016,24.1551389786684,"EDN1;CRP"]
["GO:1904355","positive regulation of telomere capping","biological_process",2,91,17,18684,0.00304253870222112,0.0119614151474016,24.1551389786684,"MAPK3;MAPK1"]
["GO:2000377","regulation of reactive oxygen species metabolic process","biological_process",2,91,17,18684,0.00304253870222112,0.0119614151474016,24.1551389786684,"EIF6;CYP1B1"]
["GO:0002576","platelet degranulation","biological_process",4,91,124,18684,0.00316592588930535,0.0123949603657897,6.62318326834456,"VEGFA;PECAM1;HGF;SPARC"]
["GO:0043524","negative regulation of neuron apoptotic process","biological_process",4,91,126,18684,0.00335305815236175,0.0129822436949395,6.51805337519623,"BCL2;BAX;IL10;NTRK1"]
["GO:0001556","oocyte maturation","biological_process",2,91,18,18684,0.00341204395366733,0.0129822436949395,22.8131868131868,"CCNB1;BRCA2"]
["GO:0001659","temperature homeostasis","biological_process",2,91,18,18684,0.00341204395366733,0.0129822436949395,22.8131868131868,"STAT3;FOXO1"]
["GO:0007250","activation of NF-kappaB-inducing kinase activity","biological_process",2,91,18,18684,0.00341204395366733,0.0129822436949395,22.8131868131868,"TNFRSF10A;TRAF2"]
["GO:0030220","platelet formation","biological_process",2,91,18,18684,0.00341204395366733,0.0129822436949395,22.8131868131868,"CASP9;CASP3"]
["GO:0031929","TOR signaling","biological_process",2,91,18,18684,0.00341204395366733,0.0129822436949395,22.8131868131868,"AKT1;MTOR"]
["GO:0032930","positive regulation of superoxide anion generation","biological_process",2,91,18,18684,0.00341204395366733,0.0129822436949395,22.8131868131868,"PRKCD;CRP"]
["GO:0051412","response to corticosterone","biological_process",2,91,18,18684,0.00341204395366733,0.0129822436949395,22.8131868131868,"CCND1;CDKN1A"]
["GO:0060716","labyrinthine layer blood vessel development","biological_process",2,91,18,18684,0.00341204395366733,0.0129822436949395,22.8131868131868,"AKT1;MAPK1"]
["GO:1902004","positive regulation of amyloid-beta formation","biological_process",2,91,18,18684,0.00341204395366733,0.0129822436949395,22.8131868131868,"RELA;CASP3"]
["GO:1902236","negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway","biological_process",2,91,18,18684,0.00341204395366733,0.0129822436949395,22.8131868131868,"BCL2L1;PTPN1"]
["GO:0045444","fat cell differentiation","biological_process",3,91,62,18684,0.00343470641191787,0.0130422285641299,9.93477490251684,"CCND1;FOXO1;SREBF1"]
["GO:0032147","activation of protein kinase activity","biological_process",3,91,64,18684,0.00375743630702019,0.0142106241131504,9.62431318681319,"VEGFA;PRKCD;PRKAG2"]
["GO:0010288","response to lead ion","biological_process",2,91,19,18684,0.0038014193610141,0.0142346218053023,21.6124927703875,"CAT;SPARC"]
["GO:0010667","negative regulation of cardiac muscle cell apoptotic process","biological_process",2,91,19,18684,0.0038014193610141,0.0142346218053023,21.6124927703875,"NFE2L2;CFLAR"]
["GO:0019373","epoxygenase P450 pathway","biological_process",2,91,19,18684,0.0038014193610141,0.0142346218053023,21.6124927703875,"CYP1A1;CYP1B1"]
["GO:0031641","regulation of myelination","biological_process",2,91,19,18684,0.0038014193610141,0.0142346218053023,21.6124927703875,"AKT1;MTOR"]
["GO:0042730","fibrinolysis","biological_process",2,91,19,18684,0.0038014193610141,0.0142346218053023,21.6124927703875,"PLAU;PLAT"]
["GO:0022617","extracellular matrix disassembly","biological_process",3,91,65,18684,0.00392550069423136,0.0146412659029418,9.47624683009298,"MMP2;MMP9;BSG"]
["GO:0048511","rhythmic process","biological_process",3,91,65,18684,0.00392550069423136,0.0146412659029418,9.47624683009298,"MAPK8;PPARG;MTOR"]
["GO:0055114","oxidation-reduction process","biological_process",8,91,523,18684,0.00397808064785671,0.0148081702856241,3.14062992456874,"PTGS1;PTGS2;CYP1A1;VCAM1;NOS3;CYP1B1;MPO;PTGES"]
["GO:0002042","cell migration involved in sprouting angiogenesis","biological_process",2,91,20,18684,0.00421046693600769,0.015460180535904,20.5318681318681,"AKT1;VEGFA"]
["GO:0002639","positive regulation of immunoglobulin production","biological_process",2,91,20,18684,0.00421046693600769,0.015460180535904,20.5318681318681,"IL10;IL6"]
["GO:0048011","neurotrophin TRK receptor signaling pathway","biological_process",2,91,20,18684,0.00421046693600769,0.015460180535904,20.5318681318681,"CASP3;NTRK1"]
["GO:0050901","leukocyte tethering or rolling","biological_process",2,91,20,18684,0.00421046693600769,0.015460180535904,20.5318681318681,"SELE;VCAM1"]
["GO:0090050","positive regulation of cell migration involved in sprouting angiogenesis","biological_process",2,91,20,18684,0.00421046693600769,0.015460180535904,20.5318681318681,"PTGS2;VEGFA"]
["GO:0097746","blood vessel diameter maintenance","biological_process",2,91,20,18684,0.00421046693600769,0.015460180535904,20.5318681318681,"NOS3;AGTR1"]
["GO:1900017","positive regulation of cytokine production involved in inflammatory response","biological_process",2,91,20,18684,0.00421046693600769,0.015460180535904,20.5318681318681,"STAT3;IL6"]
["GO:0006631","fatty acid metabolic process","biological_process",3,91,67,18684,0.00427521304715597,0.0155171360310402,9.19337379038872,"PPARG;CYP1A1;PPARA"]
["GO:0032922","circadian regulation of gene expression","biological_process",3,91,67,18684,0.00427521304715597,0.0155171360310402,9.19337379038872,"NCOA2;AHR;PPARA"]
["GO:0042531","positive regulation of tyrosine phosphorylation of STAT protein","biological_process",3,91,67,18684,0.00427521304715597,0.0155171360310402,9.19337379038872,"STAT3;VEGFA;IL6"]
["GO:1901224","positive regulation of NIK/NF-kappaB signaling","biological_process",3,91,67,18684,0.00427521304715597,0.0155171360310402,9.19337379038872,"RELA;EDN1;IL1B"]
["GO:0002052","positive regulation of neuroblast proliferation","biological_process",2,91,21,18684,0.00463899011068146,0.0166142619304899,19.5541601255887,"VEGFA;CTNNB1"]
["GO:0014066","regulation of phosphatidylinositol 3-kinase signaling","biological_process",2,91,21,18684,0.00463899011068146,0.0166142619304899,19.5541601255887,"MAPK3;MAPK1"]
["GO:0046686","response to cadmium ion","biological_process",2,91,21,18684,0.00463899011068146,0.0166142619304899,19.5541601255887,"CAT;SPARC"]
["GO:0050768","negative regulation of neurogenesis","biological_process",2,91,21,18684,0.00463899011068146,0.0166142619304899,19.5541601255887,"IL6;IL1B"]
["GO:0050807","regulation of synapse organization","biological_process",2,91,21,18684,0.00463899011068146,0.0166142619304899,19.5541601255887,"IL10;SPARC"]
["GO:0007623","circadian rhythm","biological_process",3,91,71,18684,0.00502995358110486,0.0178794181050725,8.67543723881752,"NTRK1;KLF10;SREBF1"]
["GO:0001525","angiogenesis","biological_process",5,91,227,18684,0.00505351484435562,0.0178794181050725,4.5224379145084,"VEGFA;MMP2;CXCL8;CYP1B1;BSG"]
["GO:0030878","thyroid gland development","biological_process",2,91,22,18684,0.00508679372846588,0.0178794181050725,18.6653346653347,"MAPK3;MAPK1"]
["GO:0042246","tissue regeneration","biological_process",2,91,22,18684,0.00508679372846588,0.0178794181050725,18.6653346653347,"CDKN1A;CCNB1"]
["GO:0045861","negative regulation of proteolysis","biological_process",2,91,22,18684,0.00508679372846588,0.0178794181050725,18.6653346653347,"AKT1;PLAT"]
["GO:0048714","positive regulation of oligodendrocyte differentiation","biological_process",2,91,22,18684,0.00508679372846588,0.0178794181050725,18.6653346653347,"PPARG;MTOR"]
["GO:0060045","positive regulation of cardiac muscle cell proliferation","biological_process",2,91,22,18684,0.00508679372846588,0.0178794181050725,18.6653346653347,"MAPK1;CCNB1"]
["GO:2000378","negative regulation of reactive oxygen species metabolic process","biological_process",2,91,22,18684,0.00508679372846588,0.0178794181050725,18.6653346653347,"BCL2;BRCA1"]
["GO:0006952","defense response","biological_process",3,91,72,18684,0.00523035775561393,0.0183499193244266,8.55494505494505,"STAT3;STAT1;MPO"]
["GO:0001933","negative regulation of protein phosphorylation","biological_process",3,91,73,18684,0.00543551315371317,0.0189991781398736,8.43775402679512,"XDH;CCNB1;MTOR"]
["GO:0010906","regulation of glucose metabolic process","biological_process",2,91,23,18684,0.00555368403534978,0.0191992989229368,17.8537983755375,"NCOA2;ADIPOR1"]
["GO:0035902","response to immobilization stress","biological_process",2,91,23,18684,0.00555368403534978,0.0191992989229368,17.8537983755375,"PPARG;CYP1A1"]
["GO:0045776","negative regulation of blood pressure","biological_process",2,91,23,18684,0.00555368403534978,0.0191992989229368,17.8537983755375,"NOS3;PPARA"]
["GO:0046628","positive regulation of insulin receptor signaling pathway","biological_process",2,91,23,18684,0.00555368403534978,0.0191992989229368,17.8537983755375,"ADIPOR1;IRS1"]
["GO:0071385","cellular response to glucocorticoid stimulus","biological_process",2,91,23,18684,0.00555368403534978,0.0191992989229368,17.8537983755375,"EDN1;BCL2L11"]
["GO:0030183","B cell differentiation","biological_process",3,91,74,18684,0.00564545019764406,0.0194809239484396,8.32373032373032,"IL10;VCAM1;NTRK1"]
["GO:0008203","cholesterol metabolic process","biological_process",3,91,75,18684,0.00586019853384989,0.0201851282832607,8.21274725274725,"CAT;PON1;SREBF1"]
["GO:0002092","positive regulation of receptor internalization","biological_process",2,91,24,18684,0.00603946867109302,0.0206148650849042,17.1098901098901,"VEGFA;SELE"]
["GO:0090023","positive regulation of neutrophil chemotaxis","biological_process",2,91,24,18684,0.00603946867109302,0.0206148650849042,17.1098901098901,"EDN1;CXCL8"]
["GO:0090398","cellular senescence","biological_process",2,91,24,18684,0.00603946867109302,0.0206148650849042,17.1098901098901,"CDKN1A;PRKCD"]
["GO:0001503","ossification","biological_process",3,91,76,18684,0.00607978704133678,0.0207150942255276,8.10468478889532,"BCL2;MMP9;SPARC"]
["GO:1900034","regulation of cellular response to heat","biological_process",3,91,77,18684,0.00630424383996591,0.0214412321967186,7.99942914228629,"MAPK3;MAPK1;MTOR"]
["GO:0030307","positive regulation of cell growth","biological_process",3,91,78,18684,0.0065335962986776,0.0218632898321311,7.89687235841082,"AKT1;BCL2;CDC42"]
["GO:0030593","neutrophil chemotaxis","biological_process",3,91,78,18684,0.0065335962986776,0.0218632898321311,7.89687235841082,"EDN1;CXCL8;BSG"]
["GO:0071347","cellular response to interleukin-1","biological_process",3,91,78,18684,0.0065335962986776,0.0218632898321311,7.89687235841082,"RELA;EDN1;CXCL8"]
["GO:0009314","response to radiation","biological_process",2,91,25,18684,0.00654395666048979,0.0218632898321311,16.4254945054945,"BCL2;NTRK1"]
["GO:0033137","negative regulation of peptidyl-serine phosphorylation","biological_process",2,91,25,18684,0.00654395666048979,0.0218632898321311,16.4254945054945,"BAX;HGF"]
["GO:0042759","long-chain fatty acid biosynthetic process","biological_process",2,91,25,18684,0.00654395666048979,0.0218632898321311,16.4254945054945,"PTGS2;CYP1A1"]
["GO:0043278","response to morphine","biological_process",2,91,25,18684,0.00654395666048979,0.0218632898321311,16.4254945054945,"RELA;MTOR"]
["GO:0045742","positive regulation of epidermal growth factor receptor signaling pathway","biological_process",2,91,25,18684,0.00654395666048979,0.0218632898321311,16.4254945054945,"AKT1;MMP9"]
["GO:0051149","positive regulation of muscle cell differentiation","biological_process",2,91,25,18684,0.00654395666048979,0.0218632898321311,16.4254945054945,"CTNNB1;CDC42"]
["GO:1901223","negative regulation of NIK/NF-kappaB signaling","biological_process",2,91,25,18684,0.00654395666048979,0.0218632898321311,16.4254945054945,"RELA;ADIPOR1"]
["GO:0030324","lung development","biological_process",3,91,79,18684,0.00676787104364737,0.0225317678583401,7.79691194881068,"VEGFA;SREBF1;SPARC"]
["GO:0007565","female pregnancy","biological_process",3,91,80,18684,0.00700709396637503,0.0231204469606484,7.69945054945055,"BCL2;ADIPOR2;PAPPA"]
["GO:0008210","estrogen metabolic process","biological_process",2,91,26,18684,0.0070669584046826,0.0231204469606484,15.7937447168216,"CYP1A1;CYP1B1"]
["GO:0034620","cellular response to unfolded protein","biological_process",2,91,26,18684,0.0070669584046826,0.0231204469606484,15.7937447168216,"BAX;PTPN1"]
["GO:0048678","response to axon injury","biological_process",2,91,26,18684,0.0070669584046826,0.0231204469606484,15.7937447168216,"BAX;NTRK1"]
["GO:0051493","regulation of cytoskeleton organization","biological_process",2,91,26,18684,0.0070669584046826,0.0231204469606484,15.7937447168216,"MAPK3;MAPK1"]
["GO:0097193","intrinsic apoptotic signaling pathway","biological_process",2,91,26,18684,0.0070669584046826,0.0231204469606484,15.7937447168216,"CDKN1A;BAX"]
["GO:1900740","positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway","biological_process",2,91,26,18684,0.0070669584046826,0.0231204469606484,15.7937447168216,"BCL2;MAPK8"]
["GO:2001234","negative regulation of apoptotic signaling pathway","biological_process",2,91,26,18684,0.0070669584046826,0.0231204469606484,15.7937447168216,"BCL2;BAX"]
["GO:2001238","positive regulation of extrinsic apoptotic signaling pathway","biological_process",2,91,26,18684,0.0070669584046826,0.0231204469606484,15.7937447168216,"TNFSF10;TRAF2"]
["GO:0010971","positive regulation of G2/M transition of mitotic cell cycle","biological_process",2,91,27,18684,0.00760828567252658,0.0246357332307325,15.2087912087912,"CCND1;CCNB1"]
["GO:0032870","cellular response to hormone stimulus","biological_process",2,91,27,18684,0.00760828567252658,0.0246357332307325,15.2087912087912,"NCOA2;STAT3"]
["GO:0048565","digestive tract development","biological_process",2,91,27,18684,0.00760828567252658,0.0246357332307325,15.2087912087912,"CYP1A1;CCNB1"]
["GO:0051968","positive regulation of synaptic transmission, glutamatergic","biological_process",2,91,27,18684,0.00760828567252658,0.0246357332307325,15.2087912087912,"NTRK1;CCR2"]
["GO:0071280","cellular response to copper ion","biological_process",2,91,27,18684,0.00760828567252658,0.0246357332307325,15.2087912087912,"CYP1A1;NFE2L2"]
["GO:0046330","positive regulation of JNK cascade","biological_process",3,91,84,18684,0.00801395999859427,0.0259049544569945,7.33281004709576,"IL1B;TRAF2;CDC42"]
["GO:0035987","endodermal cell differentiation","biological_process",2,91,28,18684,0.00816775159200376,0.0261340410498801,14.6656200941915,"MMP2;MMP9"]
["GO:0042744","hydrogen peroxide catabolic process","biological_process",2,91,28,18684,0.00816775159200376,0.0261340410498801,14.6656200941915,"CAT;MPO"]
["GO:0042771","intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator","biological_process",2,91,28,18684,0.00816775159200376,0.0261340410498801,14.6656200941915,"CDKN1A;BRCA2"]
["GO:0045931","positive regulation of mitotic cell cycle","biological_process",2,91,28,18684,0.00816775159200376,0.0261340410498801,14.6656200941915,"CCNB1;BRCA2"]
["GO:0071480","cellular response to gamma radiation","biological_process",2,91,28,18684,0.00816775159200376,0.0261340410498801,14.6656200941915,"CDKN1A;XRCC6"]
["GO:0010592","positive regulation of lamellipodium assembly","biological_process",2,91,29,18684,0.00874517064168716,0.0276078759322711,14.1599090564608,"MTOR;CDC42"]
["GO:0043122","regulation of I-kappaB kinase/NF-kappaB signaling","biological_process",2,91,29,18684,0.00874517064168716,0.0276078759322711,14.1599090564608,"IL1B;TRAF2"]
["GO:0045070","positive regulation of viral genome replication","biological_process",2,91,29,18684,0.00874517064168716,0.0276078759322711,14.1599090564608,"PPARA;CD28"]
["GO:0045736","negative regulation of cyclin-dependent protein serine/threonine kinase activity","biological_process",2,91,29,18684,0.00874517064168716,0.0276078759322711,14.1599090564608,"CDKN1A;CASP3"]
["GO:0046676","negative regulation of insulin secretion","biological_process",2,91,29,18684,0.00874517064168716,0.0276078759322711,14.1599090564608,"SREBF1;IRS1"]
["GO:0048147","negative regulation of fibroblast proliferation","biological_process",2,91,29,18684,0.00874517064168716,0.0276078759322711,14.1599090564608,"BAX;MYC"]
["GO:0071549","cellular response to dexamethasone stimulus","biological_process",2,91,29,18684,0.00874517064168716,0.0276078759322711,14.1599090564608,"FOXO1;CFLAR"]
["GO:1904837","beta-catenin-TCF complex assembly","biological_process",2,91,29,18684,0.00874517064168716,0.0276078759322711,14.1599090564608,"CTNNB1;MYC"]
["GO:0010800","positive regulation of peptidyl-threonine phosphorylation","biological_process",2,91,30,18684,0.00934035864225428,0.0290982177800706,13.6879120879121,"MAPK1;PRKAG2"]
["GO:0019369","arachidonic acid metabolic process","biological_process",2,91,30,18684,0.00934035864225428,0.0290982177800706,13.6879120879121,"MAPK3;CYP1B1"]
["GO:0021510","spinal cord development","biological_process",2,91,30,18684,0.00934035864225428,0.0290982177800706,13.6879120879121,"AKT1;MTOR"]
["GO:0034612","response to tumor necrosis factor","biological_process",2,91,30,18684,0.00934035864225428,0.0290982177800706,13.6879120879121,"CASP3;SELE"]
["GO:0035633","maintenance of blood-brain barrier","biological_process",2,91,30,18684,0.00934035864225428,0.0290982177800706,13.6879120879121,"IL6;PECAM1"]
["GO:0046777","protein autophosphorylation","biological_process",4,91,170,18684,0.00957467451574567,0.0297302290792694,4.83102779573368,"AKT1;NTRK1;MTOR;EIF2S1"]
["GO:0043388","positive regulation of DNA binding","biological_process",2,91,31,18684,0.00995313274804995,0.0305619287640403,13.2463665366891,"MMP9;PPARG"]
["GO:0043507","positive regulation of JUN kinase activity","biological_process",2,91,31,18684,0.00995313274804995,0.0305619287640403,13.2463665366891,"EDN1;TRAF2"]
["GO:0043552","positive regulation of phosphatidylinositol 3-kinase activity","biological_process",2,91,31,18684,0.00995313274804995,0.0305619287640403,13.2463665366891,"IRS1;CDC42"]
["GO:0045648","positive regulation of erythrocyte differentiation","biological_process",2,91,31,18684,0.00995313274804995,0.0305619287640403,13.2463665366891,"STAT3;STAT1"]
["GO:0045765","regulation of angiogenesis","biological_process",2,91,31,18684,0.00995313274804995,0.0305619287640403,13.2463665366891,"IL6;CTNNB1"]
["GO:2000352","negative regulation of endothelial cell apoptotic process","biological_process",2,91,31,18684,0.00995313274804995,0.0305619287640403,13.2463665366891,"IL10;NFE2L2"]
["GO:0071346","cellular response to interferon-gamma","biological_process",3,91,91,18684,0.00997181916838333,0.0305619287640403,6.7687477357807,"STAT1;EDN1;CDC42"]
["GO:0006357","regulation of transcription by RNA polymerase II","biological_process",15,91,1603,18684,0.0103139976799431,0.031508513106256,1.92126027434823,"RELA;STAT3;VEGFA;CDKN1A;FOXO1;PPARG;MYC;BRCA1;PRKCB;DDIT3;NFE2L2;AHR;KLF10;SREBF1;TGFA"]
["GO:0001701","in utero embryonic development","biological_process",4,91,175,18684,0.0105679070913405,0.0320208670889245,4.69299843014129,"VEGFA;EDN1;CCNB1;BCL2L11"]
["GO:0006805","xenobiotic metabolic process","biological_process",3,91,93,18684,0.0105777684894498,0.0320208670889245,6.62318326834456,"PTGS1;CYP1B1;AHR"]
["GO:0002040","sprouting angiogenesis","biological_process",2,91,32,18684,0.010583311438698,0.0320208670889245,12.8324175824176,"VEGFA;CDC42"]
["GO:0007616","long-term memory","biological_process",2,91,32,18684,0.010583311438698,0.0320208670889245,12.8324175824176,"SLC2A4;MTOR"]
["GO:0033574","response to testosterone","biological_process",2,91,32,18684,0.010583311438698,0.0320208670889245,12.8324175824176,"EDN1;CFLAR"]
["GO:0051482","positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway","biological_process",2,91,32,18684,0.010583311438698,0.0320208670889245,12.8324175824176,"EDN1;AGTR1"]
["GO:0032148","activation of protein kinase B activity","biological_process",2,91,33,18684,0.0112307145107614,0.033763563020429,12.4435564435564,"AKT1;MTOR"]
["GO:0032212","positive regulation of telomere maintenance via telomerase","biological_process",2,91,33,18684,0.0112307145107614,0.033763563020429,12.4435564435564,"MAPK3;MAPK1"]
["GO:0048536","spleen development","biological_process",2,91,33,18684,0.0112307145107614,0.033763563020429,12.4435564435564,"BCL2;BCL2L11"]
["GO:0006874","cellular calcium ion homeostasis","biological_process",3,91,96,18684,0.0115260146060192,0.0345415112836486,6.41620879120879,"EDN1;PRKCB;CCR2"]
["GO:0008584","male gonad development","biological_process",3,91,96,18684,0.0115260146060192,0.0345415112836486,6.41620879120879,"BCL2;BCL2L11;TNFSF10"]
["GO:0048469","cell maturation","biological_process",2,91,34,18684,0.0118951630694516,0.0351464896317704,12.0775694893342,"VEGFA;PPARG"]
["GO:0050767","regulation of neurogenesis","biological_process",2,91,34,18684,0.0118951630694516,0.0351464896317704,12.0775694893342,"CTNNB1;IL1B"]
["GO:0098586","cellular response to virus","biological_process",2,91,34,18684,0.0118951630694516,0.0351464896317704,12.0775694893342,"BAX;IL6"]
["GO:1990090","cellular response to nerve growth factor stimulus","biological_process",2,91,34,18684,0.0118951630694516,0.0351464896317704,12.0775694893342,"AKT1;NTRK1"]
["GO:2001237","negative regulation of extrinsic apoptotic signaling pathway","biological_process",2,91,34,18684,0.0118951630694516,0.0351464896317704,12.0775694893342,"RELA;CFLAR"]
["GO:0038083","peptidyl-tyrosine autophosphorylation","biological_process",2,91,35,18684,0.0125764795203849,0.0368715081752679,11.7324960753532,"MAPK3;NTRK1"]
["GO:0097009","energy homeostasis","biological_process",2,91,35,18684,0.0125764795203849,0.0368715081752679,11.7324960753532,"STAT3;FOXO1"]
["GO:0006953","acute-phase response","biological_process",2,91,36,18684,0.0132744875613873,0.0387377407076904,11.4065934065934,"IL6;CRP"]
["GO:0042059","negative regulation of epidermal growth factor receptor signaling pathway","biological_process",2,91,36,18684,0.0132744875613873,0.0387377407076904,11.4065934065934,"CDC42;TGFA"]
["GO:0016055","Wnt signaling pathway","biological_process",4,91,188,18684,0.0134556769609955,0.0392059863378159,4.36848258124854,"CCND1;CTNNB1;DDIT3;CCNE1"]
["GO:0006955","immune response","biological_process",5,91,291,18684,0.0138828519721322,0.0403263795380983,3.52781239379178,"IL1B;IL1A;CD80;CCR2;TNFSF10"]
["GO:0001658","branching involved in ureteric bud morphogenesis","biological_process",2,91,37,18684,0.0139890121743472,0.0403865985063978,11.0983070983071,"BCL2;MYC"]
["GO:0042594","response to starvation","biological_process",2,91,37,18684,0.0139890121743472,0.0403865985063978,11.0983070983071,"PPARG;DDIT3"]
["GO:0045746","negative regulation of Notch signaling pathway","biological_process",2,91,37,18684,0.0139890121743472,0.0403865985063978,11.0983070983071,"AKT1;NFKBIA"]
["GO:0042307","positive regulation of protein import into nucleus","biological_process",2,91,38,18684,0.014719879617115,0.0422386833929658,10.8062463851938,"MAPK1;PRKCD"]
["GO:0043491","protein kinase B signaling","biological_process",2,91,38,18684,0.014719879617115,0.0422386833929658,10.8062463851938,"AKT1;IL1B"]
["GO:1901216","positive regulation of neuron death","biological_process",2,91,38,18684,0.014719879617115,0.0422386833929658,10.8062463851938,"MTOR;EIF2S1"]
["GO:0003007","heart morphogenesis","biological_process",2,91,39,18684,0.0154669174154499,0.0441145412256647,10.5291631445478,"VEGFA;MTOR"]
["GO:0032689","negative regulation of interferon-gamma production","biological_process",2,91,39,18684,0.0154669174154499,0.0441145412256647,10.5291631445478,"IL10;DDIT3"]
["GO:2000134","negative regulation of G1/S transition of mitotic cell cycle","biological_process",2,91,40,18684,0.0162299543550134,0.0459443767744466,10.2659340659341,"BCL2;CDKN1A"]
["GO:0009408","response to heat","biological_process",2,91,41,18684,0.01700882047341,0.0479339486068826,10.0155454301796,"AKT1;NOS3"]
["GO:0042130","negative regulation of T cell proliferation","biological_process",2,91,41,18684,0.01700882047341,0.0479339486068826,10.0155454301796,"IL10;CD80"]
["GO:0009411","response to UV","biological_process",2,91,42,18684,0.0178033470522733,0.0497284036570883,9.77708006279435,"CASP3;MAPK8"]
["GO:0032465","regulation of cytokinesis","biological_process",2,91,42,18684,0.0178033470522733,0.0497284036570883,9.77708006279435,"BCL2L1;BRCA2"]
["GO:0032526","response to retinoic acid","biological_process",2,91,42,18684,0.0178033470522733,0.0497284036570883,9.77708006279435,"SREBF1;PTGES"]
["GO:0071364","cellular response to epidermal growth factor stimulus","biological_process",2,91,42,18684,0.0178033470522733,0.0497284036570883,9.77708006279435,"AKT1;CFLAR"]
["GO:0097191","extrinsic apoptotic signaling pathway","biological_process",2,91,42,18684,0.0178033470522733,0.0497284036570883,9.77708006279435,"BAX;TNFRSF10A"]
["GO:2000272","negative regulation of signaling receptor activity","biological_process",2,91,42,18684,0.0178033470522733,0.0497284036570883,9.77708006279435,"PPARG;PPARA"]
["GO:0001819","positive regulation of cytokine production","biological_process",2,91,43,18684,0.0186133666093988,0.0514588834186742,9.54970610784564,"IL10;IL1A"]
["GO:0001837","epithelial to mesenchymal transition","biological_process",2,91,43,18684,0.0186133666093988,0.0514588834186742,9.54970610784564,"CTNNB1;HGF"]
["GO:0006110","regulation of glycolytic process","biological_process",2,91,43,18684,0.0186133666093988,0.0514588834186742,9.54970610784564,"EIF6;PRKAG2"]
["GO:0006633","fatty acid biosynthetic process","biological_process",2,91,43,18684,0.0186133666093988,0.0514588834186742,9.54970610784564,"BRCA1;PRKAG2"]
["GO:0030574","collagen catabolic process","biological_process",2,91,43,18684,0.0186133666093988,0.0514588834186742,9.54970610784564,"MMP2;MMP9"]
["GO:0051726","regulation of cell cycle","biological_process",3,91,115,18684,0.0186486045899972,0.0514810383645031,5.35613951266125,"STAT3;BIRC5;CCNB1"]
["GO:0000723","telomere maintenance","biological_process",2,91,44,18684,0.0194387128909226,0.0533506619401082,9.33266733266733,"XRCC6;CCNE1"]
["GO:0008202","steroid metabolic process","biological_process",2,91,44,18684,0.0194387128909226,0.0533506619401082,9.33266733266733,"CYP1A1;CYP1B1"]
["GO:0032715","negative regulation of interleukin-6 production","biological_process",2,91,44,18684,0.0194387128909226,0.0533506619401082,9.33266733266733,"IL10;HGF"]
["GO:0071230","cellular response to amino acid stimulus","biological_process",2,91,44,18684,0.0194387128909226,0.0533506619401082,9.33266733266733,"MMP2;MTOR"]
["GO:0050918","positive chemotaxis","biological_process",2,91,45,18684,0.0202792208635447,0.0554963916830144,9.12527472527473,"VEGFA;HGF"]
["GO:0055088","lipid homeostasis","biological_process",2,91,45,18684,0.0202792208635447,0.0554963916830144,9.12527472527473,"PPARG;NR1H3"]
["GO:0007411","axon guidance","biological_process",4,91,217,18684,0.0215854773330348,0.0583979561038176,3.78467615333975,"MAPK3;MAPK1;NTRK1;BSG"]
["GO:0007157","heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules","biological_process",2,91,47,18684,0.022005067805367,0.0583979561038176,8.73696516249708,"SELE;VCAM1"]
["GO:0042572","retinol metabolic process","biological_process",2,91,47,18684,0.022005067805367,0.0583979561038176,8.73696516249708,"CYP1A1;CYP1B1"]
["GO:0120163","negative regulation of cold-induced thermogenesis","biological_process",2,91,47,18684,0.022005067805367,0.0583979561038176,8.73696516249708,"DDIT3;NR1H3"]
["GO:0018108","peptidyl-tyrosine phosphorylation","biological_process",3,91,123,18684,0.0222337901720856,0.0583979561038176,5.00777271508979,"PRKCD;NTRK1;JAK1"]
["GO:0042742","defense response to bacterium","biological_process",3,91,123,18684,0.0222337901720856,0.0583979561038176,5.00777271508979,"IL10;PRKCD;MPO"]
["GO:0065003","protein-containing complex assembly","biological_process",3,91,123,18684,0.0222337901720856,0.0583979561038176,5.00777271508979,"MAPK3;CCNB1;TRAF2"]
["GO:0007420","brain development","biological_process",4,91,219,18684,0.0222360154643182,0.0583979561038176,3.75011290079783,"XRCC6;MTOR;BCL2L11;BRCA2"]
["GO:0010212","response to ionizing radiation","biological_process",2,91,48,18684,0.0228900827414378,0.0583979561038176,8.55494505494506,"VCAM1;BRCA1"]
["GO:0045600","positive regulation of fat cell differentiation","biological_process",2,91,48,18684,0.0228900827414378,0.0583979561038176,8.55494505494506,"AKT1;PPARG"]
["GO:0007173","epidermal growth factor receptor signaling pathway","biological_process",2,91,49,18684,0.0237896112871107,0.0583979561038176,8.38035433953801,"AKT1;TGFA"]
["GO:0000054","ribosomal subunit export from nucleus","biological_process",1,91,5,18684,0.0241188808657227,0.0583979561038176,41.0637362637363,"EIF6"]
["GO:0002248","connective tissue replacement involved in inflammatory response wound healing","biological_process",1,91,5,18684,0.0241188808657227,0.0583979561038176,41.0637362637363,"IL1A"]
["GO:0002326","B cell lineage commitment","biological_process",1,91,5,18684,0.0241188808657227,0.0583979561038176,41.0637362637363,"BCL2"]
["GO:0002829","negative regulation of type 2 immune response","biological_process",1,91,5,18684,0.0241188808657227,0.0583979561038176,41.0637362637363,"CCR2"]
["GO:0003081","regulation of systemic arterial blood pressure by renin-angiotensin","biological_process",1,91,5,18684,0.0241188808657227,0.0583979561038176,41.0637362637363,"AGTR1"]
["GO:0006595","polyamine metabolic process","biological_process",1,91,5,18684,0.0241188808657227,0.0583979561038176,41.0637362637363,"ODC1"]
["GO:0006924","activation-induced cell death of T cells","biological_process",1,91,5,18684,0.0241188808657227,0.0583979561038176,41.0637362637363,"AKT1"]
["GO:0009642","response to light intensity","biological_process",1,91,5,18684,0.0241188808657227,0.0583979561038176,41.0637362637363,"CAT"]
["GO:0009750","response to fructose","biological_process",1,91,5,18684,0.0241188808657227,0.0583979561038176,41.0637362637363,"ADIPOR2"]
["GO:0009812","flavonoid metabolic process","biological_process",1,91,5,18684,0.0241188808657227,0.0583979561038176,41.0637362637363,"CYP1A1"]
["GO:0014031","mesenchymal cell development","biological_process",1,91,5,18684,0.0241188808657227,0.0583979561038176,41.0637362637363,"BCL2"]
["GO:0014910","regulation of smooth muscle cell migration","biological_process",1,91,5,18684,0.0241188808657227,0.0583979561038176,41.0637362637363,"PLAU"]
["GO:0020027","hemoglobin metabolic process","biological_process",1,91,5,18684,0.0241188808657227,0.0583979561038176,41.0637362637363,"CAT"]
["GO:0022614","membrane to membrane docking","biological_process",1,91,5,18684,0.0241188808657227,0.0583979561038176,41.0637362637363,"VCAM1"]
["GO:0031999","negative regulation of fatty acid beta-oxidation","biological_process",1,91,5,18684,0.0241188808657227,0.0583979561038176,41.0637362637363,"AKT1"]
["GO:0032025","response to cobalt ion","biological_process",1,91,5,18684,0.0241188808657227,0.0583979561038176,41.0637362637363,"CASP3"]
["GO:0032354","response to follicle-stimulating hormone","biological_process",1,91,5,18684,0.0241188808657227,0.0583979561038176,41.0637362637363,"PAPPA"]
["GO:0032376","positive regulation of cholesterol transport","biological_process",1,91,5,18684,0.0241188808657227,0.0583979561038176,41.0637362637363,"NR1H3"]
["GO:0032692","negative regulation of interleukin-1 production","biological_process",1,91,5,18684,0.0241188808657227,0.0583979561038176,41.0637362637363,"IL10"]
["GO:0032792","negative regulation of CREB transcription factor activity","biological_process",1,91,5,18684,0.0241188808657227,0.0583979561038176,41.0637362637363,"DDIT3"]
["GO:0033599","regulation of mammary gland epithelial cell proliferation","biological_process",1,91,5,18684,0.0241188808657227,0.0583979561038176,41.0637362637363,"BAX"]
["GO:0034112","positive regulation of homotypic cell-cell adhesion","biological_process",1,91,5,18684,0.0241188808657227,0.0583979561038176,41.0637362637363,"JAK1"]
["GO:0035791","platelet-derived growth factor receptor-beta signaling pathway","biological_process",1,91,5,18684,0.0241188808657227,0.0583979561038176,41.0637362637363,"PTPN1"]
["GO:0036091","positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress","biological_process",1,91,5,18684,0.0241188808657227,0.0583979561038176,41.0637362637363,"NFE2L2"]
["GO:0036324","vascular endothelial growth factor receptor-2 signaling pathway","biological_process",1,91,5,18684,0.0241188808657227,0.0583979561038176,41.0637362637363,"VEGFA"]
["GO:0036336","dendritic cell migration","biological_process",1,91,5,18684,0.0241188808657227,0.0583979561038176,41.0637362637363,"CDC42"]
["GO:0038033","positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway","biological_process",1,91,5,18684,0.0241188808657227,0.0583979561038176,41.0637362637363,"VEGFA"]
["GO:0042092","type 2 immune response","biological_process",1,91,5,18684,0.0241188808657227,0.0583979561038176,41.0637362637363,"IL10"]
["GO:0042256","mature ribosome assembly","biological_process",1,91,5,18684,0.0241188808657227,0.0583979561038176,41.0637362637363,"EIF6"]
["GO:0044381","glucose import in response to insulin stimulus","biological_process",1,91,5,18684,0.0241188808657227,0.0583979561038176,41.0637362637363,"SLC2A4"]
["GO:0045321","leukocyte activation","biological_process",1,91,5,18684,0.0241188808657227,0.0583979561038176,41.0637362637363,"EDN1"]
["GO:0045602","negative regulation of endothelial cell differentiation","biological_process",1,91,5,18684,0.0241188808657227,0.0583979561038176,41.0637362637363,"XDH"]
["GO:0045833","negative regulation of lipid metabolic process","biological_process",1,91,5,18684,0.0241188808657227,0.0583979561038176,41.0637362637363,"IL1B"]
["GO:0048066","developmental pigmentation","biological_process",1,91,5,18684,0.0241188808657227,0.0583979561038176,41.0637362637363,"BCL2L11"]
["GO:0048549","positive regulation of pinocytosis","biological_process",1,91,5,18684,0.0241188808657227,0.0583979561038176,41.0637362637363,"CDC42"]
["GO:0050904","diapedesis","biological_process",1,91,5,18684,0.0241188808657227,0.0583979561038176,41.0637362637363,"PECAM1"]
["GO:0051647","nucleus localization","biological_process",1,91,5,18684,0.0241188808657227,0.0583979561038176,41.0637362637363,"MTOR"]
["GO:0060019","radial glial cell differentiation","biological_process",1,91,5,18684,0.0241188808657227,0.0583979561038176,41.0637362637363,"STAT3"]
["GO:0060354","negative regulation of cell adhesion molecule production","biological_process",1,91,5,18684,0.0241188808657227,0.0583979561038176,41.0637362637363,"CXCL8"]
["GO:0060385","axonogenesis involved in innervation","biological_process",1,91,5,18684,0.0241188808657227,0.0583979561038176,41.0637362637363,"NTRK1"]
["GO:0060501","positive regulation of epithelial cell proliferation involved in lung morphogenesis","biological_process",1,91,5,18684,0.0241188808657227,0.0583979561038176,41.0637362637363,"CDC42"]
["GO:0060965","negative regulation of gene silencing by miRNA","biological_process",1,91,5,18684,0.0241188808657227,0.0583979561038176,41.0637362637363,"PPARG"]
["GO:0061041","regulation of wound healing","biological_process",1,91,5,18684,0.0241188808657227,0.0583979561038176,41.0637362637363,"PLAU"]
["GO:0061304","retinal blood vessel morphogenesis","biological_process",1,91,5,18684,0.0241188808657227,0.0583979561038176,41.0637362637363,"CYP1B1"]
["GO:0070200","establishment of protein localization to telomere","biological_process",1,91,5,18684,0.0241188808657227,0.0583979561038176,41.0637362637363,"BRCA2"]
["GO:0071224","cellular response to peptidoglycan","biological_process",1,91,5,18684,0.0241188808657227,0.0583979561038176,41.0637362637363,"RELA"]
["GO:0072126","positive regulation of glomerular mesangial cell proliferation","biological_process",1,91,5,18684,0.0241188808657227,0.0583979561038176,41.0637362637363,"CFLAR"]
["GO:0072162","metanephric mesenchymal cell differentiation","biological_process",1,91,5,18684,0.0241188808657227,0.0583979561038176,41.0637362637363,"STAT1"]
["GO:0072656","maintenance of protein location in mitochondrion","biological_process",1,91,5,18684,0.0241188808657227,0.0583979561038176,41.0637362637363,"AKT1"]
["GO:0072734","cellular response to staurosporine","biological_process",1,91,5,18684,0.0241188808657227,0.0583979561038176,41.0637362637363,"CASP3"]
["GO:0090335","regulation of brown fat cell differentiation","biological_process",1,91,5,18684,0.0241188808657227,0.0583979561038176,41.0637362637363,"MTOR"]
["GO:1900103","positive regulation of endoplasmic reticulum unfolded protein response","biological_process",1,91,5,18684,0.0241188808657227,0.0583979561038176,41.0637362637363,"BAX"]
["GO:1902037","negative regulation of hematopoietic stem cell differentiation","biological_process",1,91,5,18684,0.0241188808657227,0.0583979561038176,41.0637362637363,"NFE2L2"]
["GO:1902262","apoptotic process involved in blood vessel morphogenesis","biological_process",1,91,5,18684,0.0241188808657227,0.0583979561038176,41.0637362637363,"BAX"]
["GO:1902462","positive regulation of mesenchymal stem cell proliferation","biological_process",1,91,5,18684,0.0241188808657227,0.0583979561038176,41.0637362637363,"CCNE1"]
["GO:1904894","positive regulation of receptor signaling pathway via STAT","biological_process",1,91,5,18684,0.0241188808657227,0.0583979561038176,41.0637362637363,"IL6"]
["GO:1905563","negative regulation of vascular endothelial cell proliferation","biological_process",1,91,5,18684,0.0241188808657227,0.0583979561038176,41.0637362637363,"PPARG"]
["GO:1905599","positive regulation of low-density lipoprotein receptor activity","biological_process",1,91,5,18684,0.0241188808657227,0.0583979561038176,41.0637362637363,"PPARG"]
["GO:2000402","negative regulation of lymphocyte migration","biological_process",1,91,5,18684,0.0241188808657227,0.0583979561038176,41.0637362637363,"AKT1"]
["GO:2000535","regulation of entry of bacterium into host cell","biological_process",1,91,5,18684,0.0241188808657227,0.0583979561038176,41.0637362637363,"CXCL8"]
["GO:2000556","positive regulation of T-helper 1 cell cytokine production","biological_process",1,91,5,18684,0.0241188808657227,0.0583979561038176,41.0637362637363,"IL1B"]
["GO:2000660","negative regulation of interleukin-1-mediated signaling pathway","biological_process",1,91,5,18684,0.0241188808657227,0.0583979561038176,41.0637362637363,"IL6"]
["GO:0007267","cell-cell signaling","biological_process",4,91,228,18684,0.0253114842792638,0.0610510418011326,3.60208212839792,"EDN1;IL1B;KLF10;TNFSF10"]
["GO:1901796","regulation of signal transduction by p53 class mediator","biological_process",3,91,131,18684,0.0261690156557458,0.0629587895738109,4.7019545340156,"AKT1;BRCA1;PRKAG2"]
["GO:0006968","cellular defense response","biological_process",2,91,52,18684,0.0265736939931172,0.0632666810562526,7.89687235841082,"RELA;CCR2"]
["GO:0045747","positive regulation of Notch signaling pathway","biological_process",2,91,52,18684,0.0265736939931172,0.0632666810562526,7.89687235841082,"STAT3;NOS3"]
["GO:0051496","positive regulation of stress fiber assembly","biological_process",2,91,52,18684,0.0265736939931172,0.0632666810562526,7.89687235841082,"MTOR;CDC42"]
["GO:0030097","hemopoiesis","biological_process",2,91,53,18684,0.027529698233015,0.0632666810562526,7.74787476674269,"IL10;BRCA2"]
["GO:0031397","negative regulation of protein ubiquitination","biological_process",2,91,53,18684,0.027529698233015,0.0632666810562526,7.74787476674269,"AKT1;MTOR"]
["GO:0048015","phosphatidylinositol-mediated signaling","biological_process",2,91,53,18684,0.027529698233015,0.0632666810562526,7.74787476674269,"NTRK1;IRS1"]
["GO:0071345","cellular response to cytokine stimulus","biological_process",2,91,53,18684,0.027529698233015,0.0632666810562526,7.74787476674269,"STAT3;MAPK8"]
["GO:0032731","positive regulation of interleukin-1 beta production","biological_process",2,91,54,18684,0.0284994325288926,0.0632666810562526,7.60439560439561,"STAT3;IL6"]
["GO:0001957","intramembranous ossification","biological_process",1,91,6,18684,0.0288731601012935,0.0632666810562526,34.2197802197802,"MMP2"]
["GO:0002314","germinal center B cell differentiation","biological_process",1,91,6,18684,0.0288731601012935,0.0632666810562526,34.2197802197802,"IL6"]
["GO:0002719","negative regulation of cytokine production involved in immune response","biological_process",1,91,6,18684,0.0288731601012935,0.0632666810562526,34.2197802197802,"IL10"]
["GO:0003179","heart valve morphogenesis","biological_process",1,91,6,18684,0.0288731601012935,0.0632666810562526,34.2197802197802,"MTOR"]
["GO:0006207","'de novo' pyrimidine nucleobase biosynthetic process","biological_process",1,91,6,18684,0.0288731601012935,0.0632666810562526,34.2197802197802,"MTOR"]
["GO:0007127","meiosis I","biological_process",1,91,6,18684,0.0288731601012935,0.0632666810562526,34.2197802197802,"BCL2L11"]
["GO:0009635","response to herbicide","biological_process",1,91,6,18684,0.0288731601012935,0.0632666810562526,34.2197802197802,"CYP1A1"]
["GO:0014842","regulation of skeletal muscle satellite cell proliferation","biological_process",1,91,6,18684,0.0288731601012935,0.0632666810562526,34.2197802197802,"CFLAR"]
["GO:0031998","regulation of fatty acid beta-oxidation","biological_process",1,91,6,18684,0.0288731601012935,0.0632666810562526,34.2197802197802,"MTOR"]
["GO:0032411","positive regulation of transporter activity","biological_process",1,91,6,18684,0.0288731601012935,0.0632666810562526,34.2197802197802,"PON1"]
["GO:0032687","negative regulation of interferon-alpha production","biological_process",1,91,6,18684,0.0288731601012935,0.0632666810562526,34.2197802197802,"IL10"]
["GO:0033864","positive regulation of NAD(P)H oxidase activity","biological_process",1,91,6,18684,0.0288731601012935,0.0632666810562526,34.2197802197802,"AGTR1"]
["GO:0034392","negative regulation of smooth muscle cell apoptotic process","biological_process",1,91,6,18684,0.0288731601012935,0.0632666810562526,34.2197802197802,"EDN1"]
["GO:0035095","behavioral response to nicotine","biological_process",1,91,6,18684,0.0288731601012935,0.0632666810562526,34.2197802197802,"PPARA"]
["GO:0035315","hair cell differentiation","biological_process",1,91,6,18684,0.0288731601012935,0.0632666810562526,34.2197802197802,"CTNNB1"]
["GO:0036462","TRAIL-activated apoptotic signaling pathway","biological_process",1,91,6,18684,0.0288731601012935,0.0632666810562526,34.2197802197802,"TNFRSF10A"]
["GO:0043620","regulation of DNA-templated transcription in response to stress","biological_process",1,91,6,18684,0.0288731601012935,0.0632666810562526,34.2197802197802,"RELA"]
["GO:0045347","negative regulation of MHC class II biosynthetic process","biological_process",1,91,6,18684,0.0288731601012935,0.0632666810562526,34.2197802197802,"IL10"]
["GO:0045542","positive regulation of cholesterol biosynthetic process","biological_process",1,91,6,18684,0.0288731601012935,0.0632666810562526,34.2197802197802,"SREBF1"]
["GO:0045627","positive regulation of T-helper 1 cell differentiation","biological_process",1,91,6,18684,0.0288731601012935,0.0632666810562526,34.2197802197802,"CD80"]
["GO:0046323","glucose import","biological_process",1,91,6,18684,0.0288731601012935,0.0632666810562526,34.2197802197802,"SLC2A4"]
["GO:0046689","response to mercury ion","biological_process",1,91,6,18684,0.0288731601012935,0.0632666810562526,34.2197802197802,"BSG"]
["GO:0048515","spermatid differentiation","biological_process",1,91,6,18684,0.0288731601012935,0.0632666810562526,34.2197802197802,"BAX"]
["GO:0048664","neuron fate determination","biological_process",1,91,6,18684,0.0288731601012935,0.0632666810562526,34.2197802197802,"CDC42"]
["GO:0048708","astrocyte differentiation","biological_process",1,91,6,18684,0.0288731601012935,0.0632666810562526,34.2197802197802,"STAT3"]
["GO:0050882","voluntary musculoskeletal movement","biological_process",1,91,6,18684,0.0288731601012935,0.0632666810562526,34.2197802197802,"MTOR"]
["GO:0051572","negative regulation of histone H3-K4 methylation","biological_process",1,91,6,18684,0.0288731601012935,0.0632666810562526,34.2197802197802,"BRCA1"]
["GO:0051573","negative regulation of histone H3-K9 methylation","biological_process",1,91,6,18684,0.0288731601012935,0.0632666810562526,34.2197802197802,"BRCA1"]
["GO:0051902","negative regulation of mitochondrial depolarization","biological_process",1,91,6,18684,0.0288731601012935,0.0632666810562526,34.2197802197802,"BCL2"]
["GO:0060544","regulation of necroptotic process","biological_process",1,91,6,18684,0.0288731601012935,0.0632666810562526,34.2197802197802,"CFLAR"]
["GO:0060754","positive regulation of mast cell chemotaxis","biological_process",1,91,6,18684,0.0288731601012935,0.0632666810562526,34.2197802197802,"VEGFA"]
["GO:0061470","T follicular helper cell differentiation","biological_process",1,91,6,18684,0.0288731601012935,0.0632666810562526,34.2197802197802,"IL6"]
["GO:0071447","cellular response to hydroperoxide","biological_process",1,91,6,18684,0.0288731601012935,0.0632666810562526,34.2197802197802,"PRKCD"]
["GO:0072384","organelle transport along microtubule","biological_process",1,91,6,18684,0.0288731601012935,0.0632666810562526,34.2197802197802,"CDC42"]
["GO:0072574","hepatocyte proliferation","biological_process",1,91,6,18684,0.0288731601012935,0.0632666810562526,34.2197802197802,"IL6"]
["GO:0072672","neutrophil extravasation","biological_process",1,91,6,18684,0.0288731601012935,0.0632666810562526,34.2197802197802,"PECAM1"]
["GO:0090266","regulation of mitotic cell cycle spindle assembly checkpoint","biological_process",1,91,6,18684,0.0288731601012935,0.0632666810562526,34.2197802197802,"CCNB1"]
["GO:0090559","regulation of membrane permeability","biological_process",1,91,6,18684,0.0288731601012935,0.0632666810562526,34.2197802197802,"MTOR"]
["GO:0097300","programmed necrotic cell death","biological_process",1,91,6,18684,0.0288731601012935,0.0632666810562526,34.2197802197802,"TRAF2"]
["GO:0097680","double-strand break repair via classical nonhomologous end joining","biological_process",1,91,6,18684,0.0288731601012935,0.0632666810562526,34.2197802197802,"XRCC6"]
["GO:1901727","positive regulation of histone deacetylase activity","biological_process",1,91,6,18684,0.0288731601012935,0.0632666810562526,34.2197802197802,"VEGFA"]
["GO:1903243","negative regulation of cardiac muscle hypertrophy in response to stress","biological_process",1,91,6,18684,0.0288731601012935,0.0632666810562526,34.2197802197802,"FOXO1"]
["GO:1903573","negative regulation of response to endoplasmic reticulum stress","biological_process",1,91,6,18684,0.0288731601012935,0.0632666810562526,34.2197802197802,"NR1H3"]
["GO:1903898","negative regulation of PERK-mediated unfolded protein response","biological_process",1,91,6,18684,0.0288731601012935,0.0632666810562526,34.2197802197802,"PTPN1"]
["GO:1904058","positive regulation of sensory perception of pain","biological_process",1,91,6,18684,0.0288731601012935,0.0632666810562526,34.2197802197802,"MTOR"]
["GO:1904753","negative regulation of vascular associated smooth muscle cell migration","biological_process",1,91,6,18684,0.0288731601012935,0.0632666810562526,34.2197802197802,"NFE2L2"]
["GO:1904783","positive regulation of NMDA glutamate receptor activity","biological_process",1,91,6,18684,0.0288731601012935,0.0632666810562526,34.2197802197802,"CCR2"]
["GO:2000121","regulation of removal of superoxide radicals","biological_process",1,91,6,18684,0.0288731601012935,0.0632666810562526,34.2197802197802,"NFE2L2"]
["GO:2001268","negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway","biological_process",1,91,6,18684,0.0288731601012935,0.0632666810562526,34.2197802197802,"MMP9"]
["GO:0045165","cell fate commitment","biological_process",2,91,55,18684,0.0294827436352566,0.0644530268373066,7.46613386613387,"CASP3;PPARG"]
["GO:0071363","cellular response to growth factor stimulus","biological_process",2,91,55,18684,0.0294827436352566,0.0644530268373066,7.46613386613387,"CAT;CTNNB1"]
["GO:0007605","sensory perception of sound","biological_process",3,91,139,18684,0.0304536507887847,0.0664986762604986,4.43133844572694,"CASP3;BIRC5;DDIT3"]
["GO:0006355","regulation of transcription, DNA-templated","biological_process",6,91,485,18684,0.031093940147799,0.0673872405042206,2.54002492353008,"NCOA2;RELA;STAT3;DDIT3;AHR;BRCA2"]
["GO:0043406","positive regulation of MAP kinase activity","biological_process",2,91,57,18684,0.0314894889800414,0.0673872405042206,7.20416425679584,"VEGFA;EDN1"]
["GO:0051216","cartilage development","biological_process",2,91,57,18684,0.0314894889800414,0.0673872405042206,7.20416425679584,"MAPK3;EDN1"]
["GO:0007049","cell cycle","biological_process",4,91,245,18684,0.0317920447963769,0.0673872405042206,3.35214173581521,"MAPK3;MAPK1;PRKCD;AHR"]
["GO:0009791","post-embryonic development","biological_process",2,91,58,18684,0.0325126223883431,0.0673872405042206,7.07995452823039,"BCL2;MTOR"]
["GO:0045669","positive regulation of osteoblast differentiation","biological_process",2,91,59,18684,0.033548730932523,0.0673872405042206,6.95995529893835,"IL6;HGF"]
["GO:0002320","lymphoid progenitor cell differentiation","biological_process",1,91,7,18684,0.0336045308278583,0.0673872405042206,29.331240188383,"BCL2"]
["GO:0002637","regulation of immunoglobulin production","biological_process",1,91,7,18684,0.0336045308278583,0.0673872405042206,29.331240188383,"TRAF2"]
["GO:0002933","lipid hydroxylation","biological_process",1,91,7,18684,0.0336045308278583,0.0673872405042206,29.331240188383,"CYP1A1"]
["GO:0003014","renal system process","biological_process",1,91,7,18684,0.0336045308278583,0.0673872405042206,29.331240188383,"BCL2"]
["GO:0006266","DNA ligation","biological_process",1,91,7,18684,0.0336045308278583,0.0673872405042206,29.331240188383,"XRCC6"]
["GO:0006527","arginine catabolic process","biological_process",1,91,7,18684,0.0336045308278583,0.0673872405042206,29.331240188383,"NOS3"]
["GO:0007589","body fluid secretion","biological_process",1,91,7,18684,0.0336045308278583,0.0673872405042206,29.331240188383,"EDN1"]
["GO:0008228","opsonization","biological_process",1,91,7,18684,0.0336045308278583,0.0673872405042206,29.331240188383,"CRP"]
["GO:0009404","toxin metabolic process","biological_process",1,91,7,18684,0.0336045308278583,0.0673872405042206,29.331240188383,"CYP1B1"]
["GO:0009410","response to xenobiotic stimulus","biological_process",1,91,7,18684,0.0336045308278583,0.0673872405042206,29.331240188383,"AHR"]
["GO:0009804","coumarin metabolic process","biological_process",1,91,7,18684,0.0336045308278583,0.0673872405042206,29.331240188383,"CYP1A1"]
["GO:0010226","response to lithium ion","biological_process",1,91,7,18684,0.0336045308278583,0.0673872405042206,29.331240188383,"NFE2L2"]
["GO:0010883","regulation of lipid storage","biological_process",1,91,7,18684,0.0336045308278583,0.0673872405042206,29.331240188383,"SREBF1"]
["GO:0030213","hyaluronan biosynthetic process","biological_process",1,91,7,18684,0.0336045308278583,0.0673872405042206,29.331240188383,"IL1B"]
["GO:0031442","positive regulation of mRNA 3'-end processing","biological_process",1,91,7,18684,0.0336045308278583,0.0673872405042206,29.331240188383,"CCNB1"]
["GO:0031571","mitotic G1 DNA damage checkpoint","biological_process",1,91,7,18684,0.0336045308278583,0.0673872405042206,29.331240188383,"CCND1"]
["GO:0032488","Cdc42 protein signal transduction","biological_process",1,91,7,18684,0.0336045308278583,0.0673872405042206,29.331240188383,"CDC42"]
["GO:0032494","response to peptidoglycan","biological_process",1,91,7,18684,0.0336045308278583,0.0673872405042206,29.331240188383,"IL6"]
["GO:0032713","negative regulation of interleukin-4 production","biological_process",1,91,7,18684,0.0336045308278583,0.0673872405042206,29.331240188383,"DDIT3"]
["GO:0033157","regulation of intracellular protein transport","biological_process",1,91,7,18684,0.0336045308278583,0.0673872405042206,29.331240188383,"PTPN1"]
["GO:0035265","organ growth","biological_process",1,91,7,18684,0.0336045308278583,0.0673872405042206,29.331240188383,"BCL2"]
["GO:0035357","peroxisome proliferator activated receptor signaling pathway","biological_process",1,91,7,18684,0.0336045308278583,0.0673872405042206,29.331240188383,"PPARG"]
["GO:0035655","interleukin-18-mediated signaling pathway","biological_process",1,91,7,18684,0.0336045308278583,0.0673872405042206,29.331240188383,"AKT1"]
["GO:0035995","detection of muscle stretch","biological_process",1,91,7,18684,0.0336045308278583,0.0673872405042206,29.331240188383,"CTNNB1"]
["GO:0036003","positive regulation of transcription from RNA polymerase II promoter in response to stress","biological_process",1,91,7,18684,0.0336045308278583,0.0673872405042206,29.331240188383,"NFE2L2"]
["GO:0038166","angiotensin-activated signaling pathway","biological_process",1,91,7,18684,0.0336045308278583,0.0673872405042206,29.331240188383,"AGTR1"]
["GO:0042045","epithelial fluid transport","biological_process",1,91,7,18684,0.0336045308278583,0.0673872405042206,29.331240188383,"EDN1"]
["GO:0044818","mitotic G2/M transition checkpoint","biological_process",1,91,7,18684,0.0336045308278583,0.0673872405042206,29.331240188383,"BRCA1"]
["GO:0045656","negative regulation of monocyte differentiation","biological_process",1,91,7,18684,0.0336045308278583,0.0673872405042206,29.331240188383,"MYC"]
["GO:0046600","negative regulation of centriole replication","biological_process",1,91,7,18684,0.0336045308278583,0.0673872405042206,29.331240188383,"BRCA1"]
["GO:0046887","positive regulation of hormone secretion","biological_process",1,91,7,18684,0.0336045308278583,0.0673872405042206,29.331240188383,"EDN1"]
["GO:0048842","positive regulation of axon extension involved in axon guidance","biological_process",1,91,7,18684,0.0336045308278583,0.0673872405042206,29.331240188383,"VEGFA"]
["GO:0050805","negative regulation of synaptic transmission","biological_process",1,91,7,18684,0.0336045308278583,0.0673872405042206,29.331240188383,"IL1B"]
["GO:0050861","positive regulation of B cell receptor signaling pathway","biological_process",1,91,7,18684,0.0336045308278583,0.0673872405042206,29.331240188383,"PRKCB"]
["GO:0050996","positive regulation of lipid catabolic process","biological_process",1,91,7,18684,0.0336045308278583,0.0673872405042206,29.331240188383,"IL1B"]
["GO:0051099","positive regulation of binding","biological_process",1,91,7,18684,0.0336045308278583,0.0673872405042206,29.331240188383,"PON1"]
["GO:0051574","positive regulation of histone H3-K9 methylation","biological_process",1,91,7,18684,0.0336045308278583,0.0673872405042206,29.331240188383,"BRCA1"]
["GO:0051988","regulation of attachment of spindle microtubules to kinetochore","biological_process",1,91,7,18684,0.0336045308278583,0.0673872405042206,29.331240188383,"CDC42"]
["GO:0055015","ventricular cardiac muscle cell development","biological_process",1,91,7,18684,0.0336045308278583,0.0673872405042206,29.331240188383,"CCNB1"]
["GO:0060009","Sertoli cell development","biological_process",1,91,7,18684,0.0336045308278583,0.0673872405042206,29.331240188383,"NTRK1"]
["GO:0060346","bone trabecula formation","biological_process",1,91,7,18684,0.0336045308278583,0.0673872405042206,29.331240188383,"MMP2"]
["GO:0061154","endothelial tube morphogenesis","biological_process",1,91,7,18684,0.0336045308278583,0.0673872405042206,29.331240188383,"CTNNB1"]
["GO:0071499","cellular response to laminar fluid shear stress","biological_process",1,91,7,18684,0.0336045308278583,0.0673872405042206,29.331240188383,"NFE2L2"]
["GO:0086100","endothelin receptor signaling pathway","biological_process",1,91,7,18684,0.0336045308278583,0.0673872405042206,29.331240188383,"EDN1"]
["GO:0099527","postsynapse to nucleus signaling pathway","biological_process",1,91,7,18684,0.0336045308278583,0.0673872405042206,29.331240188383,"RELA"]
["GO:1900122","positive regulation of receptor binding","biological_process",1,91,7,18684,0.0336045308278583,0.0673872405042206,29.331240188383,"MMP9"]
["GO:1901165","positive regulation of trophoblast cell migration","biological_process",1,91,7,18684,0.0336045308278583,0.0673872405042206,29.331240188383,"VEGFA"]
["GO:1903026","negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding","biological_process",1,91,7,18684,0.0336045308278583,0.0673872405042206,29.331240188383,"DDIT3"]
["GO:1903071","positive regulation of ER-associated ubiquitin-dependent protein catabolic process","biological_process",1,91,7,18684,0.0336045308278583,0.0673872405042206,29.331240188383,"NFE2L2"]
["GO:1903214","regulation of protein targeting to mitochondrion","biological_process",1,91,7,18684,0.0336045308278583,0.0673872405042206,29.331240188383,"SREBF1"]
["GO:1903659","regulation of complement-dependent cytotoxicity","biological_process",1,91,7,18684,0.0336045308278583,0.0673872405042206,29.331240188383,"IL10"]
["GO:1904417","positive regulation of xenophagy","biological_process",1,91,7,18684,0.0336045308278583,0.0673872405042206,29.331240188383,"MAPK3"]
["GO:1904798","positive regulation of core promoter binding","biological_process",1,91,7,18684,0.0336045308278583,0.0673872405042206,29.331240188383,"CTNNB1"]
["GO:1904948","midbrain dopaminergic neuron differentiation","biological_process",1,91,7,18684,0.0336045308278583,0.0673872405042206,29.331240188383,"CTNNB1"]
["GO:1905461","positive regulation of vascular associated smooth muscle cell apoptotic process","biological_process",1,91,7,18684,0.0336045308278583,0.0673872405042206,29.331240188383,"PPARG"]
["GO:1905618","positive regulation of miRNA mediated inhibition of translation","biological_process",1,91,7,18684,0.0336045308278583,0.0673872405042206,29.331240188383,"STAT3"]
["GO:2000144","positive regulation of DNA-templated transcription, initiation","biological_process",1,91,7,18684,0.0336045308278583,0.0673872405042206,29.331240188383,"CTNNB1"]
["GO:2000553","positive regulation of T-helper 2 cell cytokine production","biological_process",1,91,7,18684,0.0336045308278583,0.0673872405042206,29.331240188383,"IL6"]
["GO:0007204","positive regulation of cytosolic calcium ion concentration","biological_process",3,91,146,18684,0.0344876129312427,0.0690848263273093,4.21887701339756,"EDN1;AGTR1;CCR2"]
["GO:0006302","double-strand break repair","biological_process",2,91,60,18684,0.0345976669848443,0.0692319452575033,6.84395604395604,"BRCA1;BRCA2"]
["GO:0035019","somatic stem cell population maintenance","biological_process",2,91,61,18684,0.0356592840197133,0.0712643066459148,6.73176004323545,"STAT3;KLF10"]
["GO:0098609","cell-cell adhesion","biological_process",3,91,148,18684,0.0356886823869282,0.0712643066459148,4.16186516186516,"BCL2;CTNNB1;PECAM1"]
["GO:0009611","response to wounding","biological_process",2,91,62,18684,0.0367334366066398,0.0720896281374512,6.62318326834456,"CYP1A1;CCR2"]
["GO:0009749","response to glucose","biological_process",2,91,62,18684,0.0367334366066398,0.0720896281374512,6.62318326834456,"CASP3;SREBF1"]
["GO:0038061","NIK/NF-kappaB signaling","biological_process",2,91,62,18684,0.0367334366066398,0.0720896281374512,6.62318326834456,"RELA;AKT1"]
["GO:0001893","maternal placenta development","biological_process",1,91,8,18684,0.0383131022094862,0.0720896281374512,25.6648351648352,"AKT1"]
["GO:0002446","neutrophil mediated immunity","biological_process",1,91,8,18684,0.0383131022094862,0.0720896281374512,25.6648351648352,"IL6"]
["GO:0002674","negative regulation of acute inflammatory response","biological_process",1,91,8,18684,0.0383131022094862,0.0720896281374512,25.6648351648352,"PPARG"]
["GO:0006975","DNA damage induced protein phosphorylation","biological_process",1,91,8,18684,0.0383131022094862,0.0720896281374512,25.6648351648352,"MAPK3"]
["GO:0007614","short-term memory","biological_process",1,91,8,18684,0.0383131022094862,0.0720896281374512,25.6648351648352,"SLC2A4"]
["GO:0009629","response to gravity","biological_process",1,91,8,18684,0.0383131022094862,0.0720896281374512,25.6648351648352,"SPARC"]
["GO:0010544","negative regulation of platelet activation","biological_process",1,91,8,18684,0.0383131022094862,0.0720896281374512,25.6648351648352,"NOS3"]
["GO:0014732","skeletal muscle atrophy","biological_process",1,91,8,18684,0.0383131022094862,0.0720896281374512,25.6648351648352,"CFLAR"]
["GO:0015889","cobalamin transport","biological_process",1,91,8,18684,0.0383131022094862,0.0720896281374512,25.6648351648352,"CD320"]
["GO:0019953","sexual reproduction","biological_process",1,91,8,18684,0.0383131022094862,0.0720896281374512,25.6648351648352,"STAT3"]
["GO:0022612","gland morphogenesis","biological_process",1,91,8,18684,0.0383131022094862,0.0720896281374512,25.6648351648352,"BCL2"]
["GO:0022898","regulation of transmembrane transporter activity","biological_process",1,91,8,18684,0.0383131022094862,0.0720896281374512,25.6648351648352,"BCL2"]
["GO:0032287","peripheral nervous system myelin maintenance","biological_process",1,91,8,18684,0.0383131022094862,0.0720896281374512,25.6648351648352,"AKT1"]
["GO:0032471","negative regulation of endoplasmic reticulum calcium ion concentration","biological_process",1,91,8,18684,0.0383131022094862,0.0720896281374512,25.6648351648352,"BAX"]
["GO:0032682","negative regulation of chemokine production","biological_process",1,91,8,18684,0.0383131022094862,0.0720896281374512,25.6648351648352,"IL6"]
["GO:0032835","glomerulus development","biological_process",1,91,8,18684,0.0383131022094862,0.0720896281374512,25.6648351648352,"BCL2"]
["GO:0033601","positive regulation of mammary gland epithelial cell proliferation","biological_process",1,91,8,18684,0.0383131022094862,0.0720896281374512,25.6648351648352,"CCND1"]
["GO:0035635","entry of bacterium into host cell","biological_process",1,91,8,18684,0.0383131022094862,0.0720896281374512,25.6648351648352,"CTNNB1"]
["GO:0038202","TORC1 signaling","biological_process",1,91,8,18684,0.0383131022094862,0.0720896281374512,25.6648351648352,"MTOR"]
["GO:0042994","cytoplasmic sequestering of transcription factor","biological_process",1,91,8,18684,0.0383131022094862,0.0720896281374512,25.6648351648352,"NFKBIA"]
["GO:0046620","regulation of organ growth","biological_process",1,91,8,18684,0.0383131022094862,0.0720896281374512,25.6648351648352,"BCL2L11"]
["GO:0048739","cardiac muscle fiber development","biological_process",1,91,8,18684,0.0383131022094862,0.0720896281374512,25.6648351648352,"VEGFA"]
["GO:0048743","positive regulation of skeletal muscle fiber development","biological_process",1,91,8,18684,0.0383131022094862,0.0720896281374512,25.6648351648352,"BCL2"]
["GO:0050871","positive regulation of B cell activation","biological_process",1,91,8,18684,0.0383131022094862,0.0720896281374512,25.6648351648352,"IL6"]
["GO:0051045","negative regulation of membrane protein ectodomain proteolysis","biological_process",1,91,8,18684,0.0383131022094862,0.0720896281374512,25.6648351648352,"IL10"]
["GO:0051683","establishment of Golgi localization","biological_process",1,91,8,18684,0.0383131022094862,0.0720896281374512,25.6648351648352,"CDC42"]
["GO:0060982","coronary artery morphogenesis","biological_process",1,91,8,18684,0.0383131022094862,0.0720896281374512,25.6648351648352,"VEGFA"]
["GO:0071493","cellular response to UV-B","biological_process",1,91,8,18684,0.0383131022094862,0.0720896281374512,25.6648351648352,"CDKN1A"]
["GO:0071550","death-inducing signaling complex assembly","biological_process",1,91,8,18684,0.0383131022094862,0.0720896281374512,25.6648351648352,"TRAF2"]
["GO:0072577","endothelial cell apoptotic process","biological_process",1,91,8,18684,0.0383131022094862,0.0720896281374512,25.6648351648352,"IL10"]
["GO:0075713","establishment of integrated proviral latency","biological_process",1,91,8,18684,0.0383131022094862,0.0720896281374512,25.6648351648352,"XRCC6"]
["GO:0090091","positive regulation of extracellular matrix disassembly","biological_process",1,91,8,18684,0.0383131022094862,0.0720896281374512,25.6648351648352,"IL6"]
["GO:0090279","regulation of calcium ion import","biological_process",1,91,8,18684,0.0383131022094862,0.0720896281374512,25.6648351648352,"CTNNB1"]
["GO:0150105","protein localization to cell-cell junction","biological_process",1,91,8,18684,0.0383131022094862,0.0720896281374512,25.6648351648352,"JAK1"]
["GO:1901522","positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus","biological_process",1,91,8,18684,0.0383131022094862,0.0720896281374512,25.6648351648352,"RELA"]
["GO:1903206","negative regulation of hydrogen peroxide-induced cell death","biological_process",1,91,8,18684,0.0383131022094862,0.0720896281374512,25.6648351648352,"NFE2L2"]
["GO:1903238","positive regulation of leukocyte tethering or rolling","biological_process",1,91,8,18684,0.0383131022094862,0.0720896281374512,25.6648351648352,"SELE"]
["GO:1990264","peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity","biological_process",1,91,8,18684,0.0383131022094862,0.0720896281374512,25.6648351648352,"PTPN1"]
["GO:2000271","positive regulation of fibroblast apoptotic process","biological_process",1,91,8,18684,0.0383131022094862,0.0720896281374512,25.6648351648352,"BCL2L11"]
["GO:2000617","positive regulation of histone H3-K9 acetylation","biological_process",1,91,8,18684,0.0383131022094862,0.0720896281374512,25.6648351648352,"BRCA1"]
["GO:0021987","cerebral cortex development","biological_process",2,91,64,18684,0.0389187721482793,0.0730113076710279,6.41620879120879,"BAX;BCL2A1"]
["GO:0048010","vascular endothelial growth factor receptor signaling pathway","biological_process",2,91,64,18684,0.0389187721482793,0.0730113076710279,6.41620879120879,"VEGFA;CDC42"]
["GO:0016579","protein deubiquitination","biological_process",4,91,263,18684,0.0396271136851215,0.0742664737151285,3.12271758659591,"NFKBIA;MYC;BRCA1;TRAF2"]
["GO:0032729","positive regulation of interferon-gamma production","biological_process",2,91,65,18684,0.040029669654757,0.0748725077320925,6.31749788672866,"IL1B;CCR2"]
["GO:0060337","type I interferon signaling pathway","biological_process",2,91,66,18684,0.0411525318030305,0.0764920758759111,6.22177822177822,"STAT1;JAK1"]
["GO:0030855","epithelial cell differentiation","biological_process",2,91,67,18684,0.0422872185339805,0.0764920758759111,6.12891586025914,"VEGFA;PPARG"]
["GO:0051865","protein autoubiquitination","biological_process",2,91,67,18684,0.0422872185339805,0.0764920758759111,6.12891586025914,"BRCA1;TRAF2"]
["GO:0008037","cell recognition","biological_process",1,91,9,18684,0.0429989828958718,0.0764920758759111,22.8131868131868,"PECAM1"]
["GO:0010225","response to UV-C","biological_process",1,91,9,18684,0.0429989828958718,0.0764920758759111,22.8131868131868,"BRCA2"]
["GO:0010831","positive regulation of myotube differentiation","biological_process",1,91,9,18684,0.0429989828958718,0.0764920758759111,22.8131868131868,"MTOR"]
["GO:0010873","positive regulation of cholesterol esterification","biological_process",1,91,9,18684,0.0429989828958718,0.0764920758759111,22.8131868131868,"AGTR1"]
["GO:0014824","artery smooth muscle contraction","biological_process",1,91,9,18684,0.0429989828958718,0.0764920758759111,22.8131868131868,"EDN1"]
["GO:0031000","response to caffeine","biological_process",1,91,9,18684,0.0429989828958718,0.0764920758759111,22.8131868131868,"PPARG"]
["GO:0032933","SREBP signaling pathway","biological_process",1,91,9,18684,0.0429989828958718,0.0764920758759111,22.8131868131868,"SREBF1"]
["GO:0033554","cellular response to stress","biological_process",1,91,9,18684,0.0429989828958718,0.0764920758759111,22.8131868131868,"RELA"]
["GO:0035767","endothelial cell chemotaxis","biological_process",1,91,9,18684,0.0429989828958718,0.0764920758759111,22.8131868131868,"VEGFA"]
["GO:0036500","ATF6-mediated unfolded protein response","biological_process",1,91,9,18684,0.0429989828958718,0.0764920758759111,22.8131868131868,"DDIT3"]
["GO:0038155","interleukin-23-mediated signaling pathway","biological_process",1,91,9,18684,0.0429989828958718,0.0764920758759111,22.8131868131868,"STAT3"]
["GO:0039694","viral RNA genome replication","biological_process",1,91,9,18684,0.0429989828958718,0.0764920758759111,22.8131868131868,"CDC42"]
["GO:0043117","positive regulation of vascular permeability","biological_process",1,91,9,18684,0.0429989828958718,0.0764920758759111,22.8131868131868,"VEGFA"]
["GO:0043653","mitochondrial fragmentation involved in apoptotic process","biological_process",1,91,9,18684,0.0429989828958718,0.0764920758759111,22.8131868131868,"BAX"]
["GO:0045793","positive regulation of cell size","biological_process",1,91,9,18684,0.0429989828958718,0.0764920758759111,22.8131868131868,"EDN1"]
["GO:0046324","regulation of glucose import","biological_process",1,91,9,18684,0.0429989828958718,0.0764920758759111,22.8131868131868,"PRKAG2"]
["GO:0046888","negative regulation of hormone secretion","biological_process",1,91,9,18684,0.0429989828958718,0.0764920758759111,22.8131868131868,"EDN1"]
["GO:0048304","positive regulation of isotype switching to IgG isotypes","biological_process",1,91,9,18684,0.0429989828958718,0.0764920758759111,22.8131868131868,"CD28"]
["GO:0048478","replication fork protection","biological_process",1,91,9,18684,0.0429989828958718,0.0764920758759111,22.8131868131868,"BRCA2"]
["GO:0048771","tissue remodeling","biological_process",1,91,9,18684,0.0429989828958718,0.0764920758759111,22.8131868131868,"MMP2"]
["GO:0050665","hydrogen peroxide biosynthetic process","biological_process",1,91,9,18684,0.0429989828958718,0.0764920758759111,22.8131868131868,"CYP1A1"]
["GO:0051006","positive regulation of lipoprotein lipase activity","biological_process",1,91,9,18684,0.0429989828958718,0.0764920758759111,22.8131868131868,"NR1H3"]
["GO:0051782","negative regulation of cell division","biological_process",1,91,9,18684,0.0429989828958718,0.0764920758759111,22.8131868131868,"MYC"]
["GO:0060259","regulation of feeding behavior","biological_process",1,91,9,18684,0.0429989828958718,0.0764920758759111,22.8131868131868,"STAT3"]
["GO:0060338","regulation of type I interferon-mediated signaling pathway","biological_process",1,91,9,18684,0.0429989828958718,0.0764920758759111,22.8131868131868,"PTPN1"]
["GO:0060670","branching involved in labyrinthine layer morphogenesis","biological_process",1,91,9,18684,0.0429989828958718,0.0764920758759111,22.8131868131868,"IL10"]
["GO:0061549","sympathetic ganglion development","biological_process",1,91,9,18684,0.0429989828958718,0.0764920758759111,22.8131868131868,"CTNNB1"]
["GO:0070168","negative regulation of biomineral tissue development","biological_process",1,91,9,18684,0.0429989828958718,0.0764920758759111,22.8131868131868,"NOS3"]
["GO:0071548","response to dexamethasone","biological_process",1,91,9,18684,0.0429989828958718,0.0764920758759111,22.8131868131868,"EDN1"]
["GO:0071636","positive regulation of transforming growth factor beta production","biological_process",1,91,9,18684,0.0429989828958718,0.0764920758759111,22.8131868131868,"PTGS2"]
["GO:0085020","protein K6-linked ubiquitination","biological_process",1,91,9,18684,0.0429989828958718,0.0764920758759111,22.8131868131868,"BRCA1"]
["GO:0090037","positive regulation of protein kinase C signaling","biological_process",1,91,9,18684,0.0429989828958718,0.0764920758759111,22.8131868131868,"VEGFA"]
["GO:1900744","regulation of p38MAPK cascade","biological_process",1,91,9,18684,0.0429989828958718,0.0764920758759111,22.8131868131868,"HGF"]
["GO:1902806","regulation of cell cycle G1/S phase transition","biological_process",1,91,9,18684,0.0429989828958718,0.0764920758759111,22.8131868131868,"CDKN1A"]
["GO:2000347","positive regulation of hepatocyte proliferation","biological_process",1,91,9,18684,0.0429989828958718,0.0764920758759111,22.8131868131868,"CFLAR"]
["GO:2000480","negative regulation of cAMP-dependent protein kinase activity","biological_process",1,91,9,18684,0.0429989828958718,0.0764920758759111,22.8131868131868,"PRKAG2"]
["GO:0001558","regulation of cell growth","biological_process",2,91,69,18684,0.0445915107693195,0.0792505139706609,5.95126612517917,"AGTR1;MTOR"]
["GO:0070098","chemokine-mediated signaling pathway","biological_process",2,91,70,18684,0.0457608413971314,0.0804008683476973,5.86624803767661,"CXCL8;CCR2"]
["GO:0006303","double-strand break repair via nonhomologous end joining","biological_process",2,91,71,18684,0.0469414468410742,0.0804008683476973,5.78362482587835,"BRCA1;XRCC6"]
["GO:0050796","regulation of insulin secretion","biological_process",2,91,71,18684,0.0469414468410742,0.0804008683476973,5.78362482587835,"IL6;IL1B"]
["GO:0002377","immunoglobulin production","biological_process",1,91,10,18684,0.0476622810247322,0.0804008683476973,20.5318681318681,"IL6"]
["GO:0002726","positive regulation of T cell cytokine production","biological_process",1,91,10,18684,0.0476622810247322,0.0804008683476973,20.5318681318681,"TRAF2"]
["GO:0002827","positive regulation of T-helper 1 type immune response","biological_process",1,91,10,18684,0.0476622810247322,0.0804008683476973,20.5318681318681,"CCR2"]
["GO:0006301","postreplication repair","biological_process",1,91,10,18684,0.0476622810247322,0.0804008683476973,20.5318681318681,"BRCA1"]
["GO:0006359","regulation of transcription by RNA polymerase III","biological_process",1,91,10,18684,0.0476622810247322,0.0804008683476973,20.5318681318681,"BRCA1"]
["GO:0009048","dosage compensation by inactivation of X chromosome","biological_process",1,91,10,18684,0.0476622810247322,0.0804008683476973,20.5318681318681,"BRCA1"]
["GO:0009651","response to salt stress","biological_process",1,91,10,18684,0.0476622810247322,0.0804008683476973,20.5318681318681,"BAX"]
["GO:0009967","positive regulation of signal transduction","biological_process",1,91,10,18684,0.0476622810247322,0.0804008683476973,20.5318681318681,"CD80"]
["GO:0010591","regulation of lamellipodium assembly","biological_process",1,91,10,18684,0.0476622810247322,0.0804008683476973,20.5318681318681,"CDC42"]
["GO:0010761","fibroblast migration","biological_process",1,91,10,18684,0.0476622810247322,0.0804008683476973,20.5318681318681,"AKT1"]
["GO:0014075","response to amine","biological_process",1,91,10,18684,0.0476622810247322,0.0804008683476973,20.5318681318681,"ADIPOR2"]
["GO:0030857","negative regulation of epithelial cell differentiation","biological_process",1,91,10,18684,0.0476622810247322,0.0804008683476973,20.5318681318681,"CCND1"]
["GO:0031284","positive regulation of guanylate cyclase activity","biological_process",1,91,10,18684,0.0476622810247322,0.0804008683476973,20.5318681318681,"NOS3"]
["GO:0032099","negative regulation of appetite","biological_process",1,91,10,18684,0.0476622810247322,0.0804008683476973,20.5318681318681,"PPARA"]
["GO:0033327","Leydig cell differentiation","biological_process",1,91,10,18684,0.0476622810247322,0.0804008683476973,20.5318681318681,"CCND1"]
["GO:0033629","negative regulation of cell adhesion mediated by integrin","biological_process",1,91,10,18684,0.0476622810247322,0.0804008683476973,20.5318681318681,"CYP1B1"]
["GO:0033689","negative regulation of osteoblast proliferation","biological_process",1,91,10,18684,0.0476622810247322,0.0804008683476973,20.5318681318681,"BCL2"]
["GO:0033762","response to glucagon","biological_process",1,91,10,18684,0.0476622810247322,0.0804008683476973,20.5318681318681,"SREBF1"]
["GO:0034115","negative regulation of heterotypic cell-cell adhesion","biological_process",1,91,10,18684,0.0476622810247322,0.0804008683476973,20.5318681318681,"IL10"]
["GO:0035067","negative regulation of histone acetylation","biological_process",1,91,10,18684,0.0476622810247322,0.0804008683476973,20.5318681318681,"BRCA1"]
["GO:0035456","response to interferon-beta","biological_process",1,91,10,18684,0.0476622810247322,0.0804008683476973,20.5318681318681,"STAT1"]
["GO:0042789","mRNA transcription by RNA polymerase II","biological_process",1,91,10,18684,0.0476622810247322,0.0804008683476973,20.5318681318681,"SREBF1"]
["GO:0043031","negative regulation of macrophage activation","biological_process",1,91,10,18684,0.0476622810247322,0.0804008683476973,20.5318681318681,"NR1H3"]
["GO:0044320","cellular response to leptin stimulus","biological_process",1,91,10,18684,0.0476622810247322,0.0804008683476973,20.5318681318681,"STAT3"]
["GO:0045670","regulation of osteoclast differentiation","biological_process",1,91,10,18684,0.0476622810247322,0.0804008683476973,20.5318681318681,"MTOR"]
["GO:0046622","positive regulation of organ growth","biological_process",1,91,10,18684,0.0476622810247322,0.0804008683476973,20.5318681318681,"AKT1"]
["GO:0051247","positive regulation of protein metabolic process","biological_process",1,91,10,18684,0.0476622810247322,0.0804008683476973,20.5318681318681,"MAPK8"]
["GO:0051272","positive regulation of cellular component movement","biological_process",1,91,10,18684,0.0476622810247322,0.0804008683476973,20.5318681318681,"VEGFA"]
["GO:0055013","cardiac muscle cell development","biological_process",1,91,10,18684,0.0476622810247322,0.0804008683476973,20.5318681318681,"MTOR"]
["GO:0060068","vagina development","biological_process",1,91,10,18684,0.0476622810247322,0.0804008683476973,20.5318681318681,"BAX"]
["GO:0060644","mammary gland epithelial cell differentiation","biological_process",1,91,10,18684,0.0476622810247322,0.0804008683476973,20.5318681318681,"AKT1"]
["GO:0061052","negative regulation of cell growth involved in cardiac muscle cell development","biological_process",1,91,10,18684,0.0476622810247322,0.0804008683476973,20.5318681318681,"PPARA"]
["GO:0071223","cellular response to lipoteichoic acid","biological_process",1,91,10,18684,0.0476622810247322,0.0804008683476973,20.5318681318681,"RELA"]
["GO:0071233","cellular response to leucine","biological_process",1,91,10,18684,0.0476622810247322,0.0804008683476973,20.5318681318681,"MTOR"]
["GO:0071470","cellular response to osmotic stress","biological_process",1,91,10,18684,0.0476622810247322,0.0804008683476973,20.5318681318681,"SLC2A4"]
["GO:0071481","cellular response to X-ray","biological_process",1,91,10,18684,0.0476622810247322,0.0804008683476973,20.5318681318681,"XRCC6"]
["GO:0071498","cellular response to fluid shear stress","biological_process",1,91,10,18684,0.0476622810247322,0.0804008683476973,20.5318681318681,"NFE2L2"]
["GO:0090331","negative regulation of platelet aggregation","biological_process",1,91,10,18684,0.0476622810247322,0.0804008683476973,20.5318681318681,"PRKCD"]
["GO:0140052","cellular response to oxidised low-density lipoprotein particle stimulus","biological_process",1,91,10,18684,0.0476622810247322,0.0804008683476973,20.5318681318681,"AKT1"]
["GO:1901030","positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway","biological_process",1,91,10,18684,0.0476622810247322,0.0804008683476973,20.5318681318681,"BAX"]
["GO:1901838","positive regulation of transcription of nucleolar large rRNA by RNA polymerase I","biological_process",1,91,10,18684,0.0476622810247322,0.0804008683476973,20.5318681318681,"MTOR"]
["GO:1903140","regulation of establishment of endothelial barrier","biological_process",1,91,10,18684,0.0476622810247322,0.0804008683476973,20.5318681318681,"IL1B"]
["GO:1904322","cellular response to forskolin","biological_process",1,91,10,18684,0.0476622810247322,0.0804008683476973,20.5318681318681,"AHR"]
["GO:1990253","cellular response to leucine starvation","biological_process",1,91,10,18684,0.0476622810247322,0.0804008683476973,20.5318681318681,"MTOR"]
["GO:2000008","regulation of protein localization to cell surface","biological_process",1,91,10,18684,0.0476622810247322,0.0804008683476973,20.5318681318681,"CTNNB1"]
["GO:2000048","negative regulation of cell-cell adhesion mediated by cadherin","biological_process",1,91,10,18684,0.0476622810247322,0.0804008683476973,20.5318681318681,"VEGFA"]
["GO:2001171","positive regulation of ATP biosynthetic process","biological_process",1,91,10,18684,0.0476622810247322,0.0804008683476973,20.5318681318681,"PPARA"]
["GO:0032956","regulation of actin cytoskeleton organization","biological_process",2,91,72,18684,0.0481331922435159,0.0811228756974052,5.7032967032967,"PRKCD;MTOR"]
["GO:0050852","T cell receptor signaling pathway","biological_process",3,91,168,18684,0.0488650465069587,0.0822829946078887,3.66640502354788,"RELA;MAPK1;CD28"]
["GO:0001889","liver development","biological_process",2,91,73,18684,0.0493359437671724,0.082928239701087,5.62516935119675,"RELA;HGF"]
["GO:0007059","chromosome segregation","biological_process",2,91,73,18684,0.0493359437671724,0.082928239701087,5.62516935119675,"BRCA1;BIRC5"]
["GO:0000722","telomere maintenance via recombination","biological_process",1,91,11,18684,0.052303104224194,0.0854103368635155,18.6653346653347,"BRCA2"]
["GO:0002675","positive regulation of acute inflammatory response","biological_process",1,91,11,18684,0.052303104224194,0.0854103368635155,18.6653346653347,"IL6"]
["GO:0006853","carnitine shuttle","biological_process",1,91,11,18684,0.052303104224194,0.0854103368635155,18.6653346653347,"PRKAG2"]
["GO:0006885","regulation of pH","biological_process",1,91,11,18684,0.052303104224194,0.0854103368635155,18.6653346653347,"EDN1"]
["GO:0006983","ER overload response","biological_process",1,91,11,18684,0.052303104224194,0.0854103368635155,18.6653346653347,"DDIT3"]
["GO:0010917","negative regulation of mitochondrial membrane potential","biological_process",1,91,11,18684,0.052303104224194,0.0854103368635155,18.6653346653347,"BAX"]
["GO:0010918","positive regulation of mitochondrial membrane potential","biological_process",1,91,11,18684,0.052303104224194,0.0854103368635155,18.6653346653347,"AKT1"]
["GO:0031065","positive regulation of histone deacetylation","biological_process",1,91,11,18684,0.052303104224194,0.0854103368635155,18.6653346653347,"SREBF1"]
["GO:0034145","positive regulation of toll-like receptor 4 signaling pathway","biological_process",1,91,11,18684,0.052303104224194,0.0854103368635155,18.6653346653347,"NR1H3"]
["GO:0034333","adherens junction assembly","biological_process",1,91,11,18684,0.052303104224194,0.0854103368635155,18.6653346653347,"CTNNB1"]
["GO:0038110","interleukin-2-mediated signaling pathway","biological_process",1,91,11,18684,0.052303104224194,0.0854103368635155,18.6653346653347,"JAK1"]
["GO:0042770","signal transduction in response to DNA damage","biological_process",1,91,11,18684,0.052303104224194,0.0854103368635155,18.6653346653347,"CASP9"]
["GO:0043129","surfactant homeostasis","biological_process",1,91,11,18684,0.052303104224194,0.0854103368635155,18.6653346653347,"VEGFA"]
["GO:0045060","negative thymic T cell selection","biological_process",1,91,11,18684,0.052303104224194,0.0854103368635155,18.6653346653347,"CD28"]
["GO:0045348","positive regulation of MHC class II biosynthetic process","biological_process",1,91,11,18684,0.052303104224194,0.0854103368635155,18.6653346653347,"IL10"]
["GO:0045637","regulation of myeloid cell differentiation","biological_process",1,91,11,18684,0.052303104224194,0.0854103368635155,18.6653346653347,"PRKCB"]
["GO:0045945","positive regulation of transcription by RNA polymerase III","biological_process",1,91,11,18684,0.052303104224194,0.0854103368635155,18.6653346653347,"MTOR"]
["GO:0046688","response to copper ion","biological_process",1,91,11,18684,0.052303104224194,0.0854103368635155,18.6653346653347,"IL1A"]
["GO:0051974","negative regulation of telomerase activity","biological_process",1,91,11,18684,0.052303104224194,0.0854103368635155,18.6653346653347,"PPARG"]
["GO:0071310","cellular response to organic substance","biological_process",1,91,11,18684,0.052303104224194,0.0854103368635155,18.6653346653347,"IL1B"]
["GO:0071639","positive regulation of monocyte chemotactic protein-1 production","biological_process",1,91,11,18684,0.052303104224194,0.0854103368635155,18.6653346653347,"IL1B"]
["GO:0072425","signal transduction involved in G2 DNA damage checkpoint","biological_process",1,91,11,18684,0.052303104224194,0.0854103368635155,18.6653346653347,"BRCA1"]
["GO:1900747","negative regulation of vascular endothelial growth factor signaling pathway","biological_process",1,91,11,18684,0.052303104224194,0.0854103368635155,18.6653346653347,"XDH"]
["GO:1903265","positive regulation of tumor necrosis factor-mediated signaling pathway","biological_process",1,91,11,18684,0.052303104224194,0.0854103368635155,18.6653346653347,"TRAF2"]
["GO:1990440","positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress","biological_process",1,91,11,18684,0.052303104224194,0.0854103368635155,18.6653346653347,"DDIT3"]
["GO:2000304","positive regulation of ceramide biosynthetic process","biological_process",1,91,11,18684,0.052303104224194,0.0854103368635155,18.6653346653347,"PRKCD"]
["GO:2000637","positive regulation of gene silencing by miRNA","biological_process",1,91,11,18684,0.052303104224194,0.0854103368635155,18.6653346653347,"STAT3"]
["GO:2001020","regulation of response to DNA damage stimulus","biological_process",1,91,11,18684,0.052303104224194,0.0854103368635155,18.6653346653347,"CASP9"]
["GO:0006469","negative regulation of protein kinase activity","biological_process",2,91,76,18684,0.0530089118603376,0.0864882246142351,5.40312319259688,"AKT1;PRKAG2"]
["GO:0043161","proteasome-mediated ubiquitin-dependent protein catabolic process","biological_process",3,91,174,18684,0.0532225684679141,0.0867619629076082,3.5399772641152,"CTNNB1;DDIT3;NFE2L2"]
["GO:0002687","positive regulation of leukocyte migration","biological_process",1,91,12,18684,0.0569215596151652,0.0897737024456025,17.1098901098901,"VEGFA"]
["GO:0009650","UV protection","biological_process",1,91,12,18684,0.0569215596151652,0.0897737024456025,17.1098901098901,"CAT"]
["GO:0019725","cellular homeostasis","biological_process",1,91,12,18684,0.0569215596151652,0.0897737024456025,17.1098901098901,"CCR2"]
["GO:0021854","hypothalamus development","biological_process",1,91,12,18684,0.0569215596151652,0.0897737024456025,17.1098901098901,"BAX"]
["GO:0030595","leukocyte chemotaxis","biological_process",1,91,12,18684,0.0569215596151652,0.0897737024456025,17.1098901098901,"IL10"]
["GO:0031668","cellular response to extracellular stimulus","biological_process",1,91,12,18684,0.0569215596151652,0.0897737024456025,17.1098901098901,"CDKN1A"]
["GO:0032026","response to magnesium ion","biological_process",1,91,12,18684,0.0569215596151652,0.0897737024456025,17.1098901098901,"CCND1"]
["GO:0032204","regulation of telomere maintenance","biological_process",1,91,12,18684,0.0569215596151652,0.0897737024456025,17.1098901098901,"MYC"]
["GO:0035195","gene silencing by miRNA","biological_process",1,91,12,18684,0.0569215596151652,0.0897737024456025,17.1098901098901,"EIF6"]
["GO:0035278","miRNA mediated inhibition of translation","biological_process",1,91,12,18684,0.0569215596151652,0.0897737024456025,17.1098901098901,"EIF6"]
["GO:0038180","nerve growth factor signaling pathway","biological_process",1,91,12,18684,0.0569215596151652,0.0897737024456025,17.1098901098901,"NTRK1"]
["GO:0042359","vitamin D metabolic process","biological_process",1,91,12,18684,0.0569215596151652,0.0897737024456025,17.1098901098901,"CYP1A1"]
["GO:0044030","regulation of DNA methylation","biological_process",1,91,12,18684,0.0569215596151652,0.0897737024456025,17.1098901098901,"BRCA1"]
["GO:0045475","locomotor rhythm","biological_process",1,91,12,18684,0.0569215596151652,0.0897737024456025,17.1098901098901,"NCOA2"]
["GO:0045717","negative regulation of fatty acid biosynthetic process","biological_process",1,91,12,18684,0.0569215596151652,0.0897737024456025,17.1098901098901,"BRCA1"]
["GO:0045723","positive regulation of fatty acid biosynthetic process","biological_process",1,91,12,18684,0.0569215596151652,0.0897737024456025,17.1098901098901,"NR1H3"]
["GO:0048012","hepatocyte growth factor receptor signaling pathway","biological_process",1,91,12,18684,0.0569215596151652,0.0897737024456025,17.1098901098901,"HGF"]
["GO:0048016","inositol phosphate-mediated signaling","biological_process",1,91,12,18684,0.0569215596151652,0.0897737024456025,17.1098901098901,"EDN1"]
["GO:0048546","digestive tract morphogenesis","biological_process",1,91,12,18684,0.0569215596151652,0.0897737024456025,17.1098901098901,"BCL2"]
["GO:0050673","epithelial cell proliferation","biological_process",1,91,12,18684,0.0569215596151652,0.0897737024456025,17.1098901098901,"HGF"]
["GO:0050732","negative regulation of peptidyl-tyrosine phosphorylation","biological_process",1,91,12,18684,0.0569215596151652,0.0897737024456025,17.1098901098901,"PRKCD"]
["GO:0050927","positive regulation of positive chemotaxis","biological_process",1,91,12,18684,0.0569215596151652,0.0897737024456025,17.1098901098901,"VEGFA"]
["GO:0051276","chromosome organization","biological_process",1,91,12,18684,0.0569215596151652,0.0897737024456025,17.1098901098901,"MYC"]
["GO:0060100","positive regulation of phagocytosis, engulfment","biological_process",1,91,12,18684,0.0569215596151652,0.0897737024456025,17.1098901098901,"PPARG"]
["GO:0060396","growth hormone receptor signaling pathway","biological_process",1,91,12,18684,0.0569215596151652,0.0897737024456025,17.1098901098901,"STAT3"]
["GO:0071679","commissural neuron axon guidance","biological_process",1,91,12,18684,0.0569215596151652,0.0897737024456025,17.1098901098901,"VEGFA"]
["GO:1903800","positive regulation of production of miRNAs involved in gene silencing by miRNA","biological_process",1,91,12,18684,0.0569215596151652,0.0897737024456025,17.1098901098901,"IL6"]
["GO:0000724","double-strand break repair via homologous recombination","biological_process",2,91,80,18684,0.0580523447554905,0.0914046494026915,5.13296703296703,"BRCA1;BRCA2"]
["GO:0008543","fibroblast growth factor receptor signaling pathway","biological_process",2,91,80,18684,0.0580523447554905,0.0914046494026915,5.13296703296703,"MAPK3;MAPK1"]
["GO:0000460","maturation of 5.8S rRNA","biological_process",1,91,13,18684,0.0615177538136986,0.09450046503794,15.7937447168216,"EIF6"]
["GO:0000470","maturation of LSU-rRNA","biological_process",1,91,13,18684,0.0615177538136986,0.09450046503794,15.7937447168216,"EIF6"]
["GO:0001833","inner cell mass cell proliferation","biological_process",1,91,13,18684,0.0615177538136986,0.09450046503794,15.7937447168216,"BRCA2"]
["GO:0001952","regulation of cell-matrix adhesion","biological_process",1,91,13,18684,0.0615177538136986,0.09450046503794,15.7937447168216,"BCL2"]
["GO:0002523","leukocyte migration involved in inflammatory response","biological_process",1,91,13,18684,0.0615177538136986,0.09450046503794,15.7937447168216,"SELE"]
["GO:0002690","positive regulation of leukocyte chemotaxis","biological_process",1,91,13,18684,0.0615177538136986,0.09450046503794,15.7937447168216,"IL6"]
["GO:0006195","purine nucleotide catabolic process","biological_process",1,91,13,18684,0.0615177538136986,0.09450046503794,15.7937447168216,"XDH"]
["GO:0007097","nuclear migration","biological_process",1,91,13,18684,0.0615177538136986,0.09450046503794,15.7937447168216,"CDC42"]
["GO:0010248","establishment or maintenance of transmembrane electrochemical gradient","biological_process",1,91,13,18684,0.0615177538136986,0.09450046503794,15.7937447168216,"BAX"]
["GO:0010259","multicellular organism aging","biological_process",1,91,13,18684,0.0615177538136986,0.09450046503794,15.7937447168216,"EDN1"]
["GO:0010763","positive regulation of fibroblast migration","biological_process",1,91,13,18684,0.0615177538136986,0.09450046503794,15.7937447168216,"AKT1"]
["GO:0016572","histone phosphorylation","biological_process",1,91,13,18684,0.0615177538136986,0.09450046503794,15.7937447168216,"PRKCD"]
["GO:0030195","negative regulation of blood coagulation","biological_process",1,91,13,18684,0.0615177538136986,0.09450046503794,15.7937447168216,"EDN1"]
["GO:0030948","negative regulation of vascular endothelial growth factor receptor signaling pathway","biological_process",1,91,13,18684,0.0615177538136986,0.09450046503794,15.7937447168216,"PTPN1"]
["GO:0031274","positive regulation of pseudopodium assembly","biological_process",1,91,13,18684,0.0615177538136986,0.09450046503794,15.7937447168216,"CDC42"]
["GO:0031669","cellular response to nutrient levels","biological_process",1,91,13,18684,0.0615177538136986,0.09450046503794,15.7937447168216,"MTOR"]
["GO:0033628","regulation of cell adhesion mediated by integrin","biological_process",1,91,13,18684,0.0615177538136986,0.09450046503794,15.7937447168216,"PLAU"]
["GO:0035810","positive regulation of urine volume","biological_process",1,91,13,18684,0.0615177538136986,0.09450046503794,15.7937447168216,"EDN1"]
["GO:0035815","positive regulation of renal sodium excretion","biological_process",1,91,13,18684,0.0615177538136986,0.09450046503794,15.7937447168216,"EDN1"]
["GO:0045580","regulation of T cell differentiation","biological_process",1,91,13,18684,0.0615177538136986,0.09450046503794,15.7937447168216,"CCR2"]
["GO:0045722","positive regulation of gluconeogenesis","biological_process",1,91,13,18684,0.0615177538136986,0.09450046503794,15.7937447168216,"PPARA"]
["GO:0045741","positive regulation of epidermal growth factor-activated receptor activity","biological_process",1,91,13,18684,0.0615177538136986,0.09450046503794,15.7937447168216,"TGFA"]
["GO:0045744","negative regulation of G protein-coupled receptor signaling pathway","biological_process",1,91,13,18684,0.0615177538136986,0.09450046503794,15.7937447168216,"CXCL8"]
["GO:0045820","negative regulation of glycolytic process","biological_process",1,91,13,18684,0.0615177538136986,0.09450046503794,15.7937447168216,"PPARA"]
["GO:0048599","oocyte development","biological_process",1,91,13,18684,0.0615177538136986,0.09450046503794,15.7937447168216,"BCL2"]
["GO:0050872","white fat cell differentiation","biological_process",1,91,13,18684,0.0615177538136986,0.09450046503794,15.7937447168216,"PPARG"]
["GO:0051492","regulation of stress fiber assembly","biological_process",1,91,13,18684,0.0615177538136986,0.09450046503794,15.7937447168216,"CDC42"]
["GO:0007596","blood coagulation","biological_process",3,91,185,18684,0.0616798915934059,0.0946726258142293,3.32949212949213,"PLAU;PLAT;CDC42"]
["GO:0003376","sphingosine-1-phosphate receptor signaling pathway","biological_process",1,91,14,18684,0.066091792933347,0.0998239460359099,14.6656200941915,"AKT1"]
["GO:0006349","regulation of gene expression by genetic imprinting","biological_process",1,91,14,18684,0.066091792933347,0.0998239460359099,14.6656200941915,"BRCA1"]
["GO:0008610","lipid biosynthetic process","biological_process",1,91,14,18684,0.066091792933347,0.0998239460359099,14.6656200941915,"SREBF1"]
["GO:0016064","immunoglobulin mediated immune response","biological_process",1,91,14,18684,0.066091792933347,0.0998239460359099,14.6656200941915,"PRKCD"]
["GO:0031529","ruffle organization","biological_process",1,91,14,18684,0.066091792933347,0.0998239460359099,14.6656200941915,"MTOR"]
["GO:0032700","negative regulation of interleukin-17 production","biological_process",1,91,14,18684,0.066091792933347,0.0998239460359099,14.6656200941915,"DDIT3"]
["GO:0033147","negative regulation of intracellular estrogen receptor signaling pathway","biological_process",1,91,14,18684,0.066091792933347,0.0998239460359099,14.6656200941915,"BRCA1"]
["GO:0034356","NAD biosynthesis via nicotinamide riboside salvage pathway","biological_process",1,91,14,18684,0.066091792933347,0.0998239460359099,14.6656200941915,"PTGS2"]
["GO:0038084","vascular endothelial growth factor signaling pathway","biological_process",1,91,14,18684,0.066091792933347,0.0998239460359099,14.6656200941915,"VEGFA"]
["GO:0045019","negative regulation of nitric oxide biosynthetic process","biological_process",1,91,14,18684,0.066091792933347,0.0998239460359099,14.6656200941915,"IL10"]
["GO:0046007","negative regulation of activated T cell proliferation","biological_process",1,91,14,18684,0.066091792933347,0.0998239460359099,14.6656200941915,"CASP3"]
["GO:0050862","positive regulation of T cell receptor signaling pathway","biological_process",1,91,14,18684,0.066091792933347,0.0998239460359099,14.6656200941915,"RELA"]
["GO:0050966","detection of mechanical stimulus involved in sensory perception of pain","biological_process",1,91,14,18684,0.066091792933347,0.0998239460359099,14.6656200941915,"NTRK1"]
["GO:0051489","regulation of filopodium assembly","biological_process",1,91,14,18684,0.066091792933347,0.0998239460359099,14.6656200941915,"CDC42"]
["GO:0060416","response to growth hormone","biological_process",1,91,14,18684,0.066091792933347,0.0998239460359099,14.6656200941915,"AKT1"]
["GO:0070365","hepatocyte differentiation","biological_process",1,91,14,18684,0.066091792933347,0.0998239460359099,14.6656200941915,"CYP1A1"]
["GO:2000279","negative regulation of DNA biosynthetic process","biological_process",1,91,14,18684,0.066091792933347,0.0998239460359099,14.6656200941915,"CDKN1A"]
["GO:0006351","transcription, DNA-templated","biological_process",2,91,87,18684,0.0672575318874276,0.101503585633779,4.71996968548693,"RELA;RUNX1T1"]
["GO:0000302","response to reactive oxygen species","biological_process",1,91,15,18684,0.0706437825875019,0.10347590462662,13.6879120879121,"CAT"]
["GO:0000729","DNA double-strand break processing","biological_process",1,91,15,18684,0.0706437825875019,0.10347590462662,13.6879120879121,"BRCA1"]
["GO:0003184","pulmonary valve morphogenesis","biological_process",1,91,15,18684,0.0706437825875019,0.10347590462662,13.6879120879121,"NOS3"]
["GO:0010820","positive regulation of T cell chemotaxis","biological_process",1,91,15,18684,0.0706437825875019,0.10347590462662,13.6879120879121,"CCR2"]
["GO:0015671","oxygen transport","biological_process",1,91,15,18684,0.0706437825875019,0.10347590462662,13.6879120879121,"MYC"]
["GO:0030194","positive regulation of blood coagulation","biological_process",1,91,15,18684,0.0706437825875019,0.10347590462662,13.6879120879121,"NFE2L2"]
["GO:0032516","positive regulation of phosphoprotein phosphatase activity","biological_process",1,91,15,18684,0.0706437825875019,0.10347590462662,13.6879120879121,"MTOR"]
["GO:0042462","eye photoreceptor cell development","biological_process",1,91,15,18684,0.0706437825875019,0.10347590462662,13.6879120879121,"VEGFA"]
["GO:0042574","retinal metabolic process","biological_process",1,91,15,18684,0.0706437825875019,0.10347590462662,13.6879120879121,"CYP1B1"]
["GO:0043403","skeletal muscle tissue regeneration","biological_process",1,91,15,18684,0.0706437825875019,0.10347590462662,13.6879120879121,"CFLAR"]
["GO:0045589","regulation of regulatory T cell differentiation","biological_process",1,91,15,18684,0.0706437825875019,0.10347590462662,13.6879120879121,"CD28"]
["GO:0045987","positive regulation of smooth muscle contraction","biological_process",1,91,15,18684,0.0706437825875019,0.10347590462662,13.6879120879121,"EDN1"]
["GO:0046426","negative regulation of receptor signaling pathway via JAK-STAT","biological_process",1,91,15,18684,0.0706437825875019,0.10347590462662,13.6879120879121,"ADIPOR1"]
["GO:0048485","sympathetic nervous system development","biological_process",1,91,15,18684,0.0706437825875019,0.10347590462662,13.6879120879121,"NTRK1"]
["GO:0048566","embryonic digestive tract development","biological_process",1,91,15,18684,0.0706437825875019,0.10347590462662,13.6879120879121,"CXCL8"]
["GO:0048593","camera-type eye morphogenesis","biological_process",1,91,15,18684,0.0706437825875019,0.10347590462662,13.6879120879121,"VEGFA"]
["GO:0050965","detection of temperature stimulus involved in sensory perception of pain","biological_process",1,91,15,18684,0.0706437825875019,0.10347590462662,13.6879120879121,"NTRK1"]
["GO:0051044","positive regulation of membrane protein ectodomain proteolysis","biological_process",1,91,15,18684,0.0706437825875019,0.10347590462662,13.6879120879121,"IL1B"]
["GO:0070848","response to growth factor","biological_process",1,91,15,18684,0.0706437825875019,0.10347590462662,13.6879120879121,"MYC"]
["GO:0070885","negative regulation of calcineurin-NFAT signaling cascade","biological_process",1,91,15,18684,0.0706437825875019,0.10347590462662,13.6879120879121,"MTOR"]
["GO:0071354","cellular response to interleukin-6","biological_process",1,91,15,18684,0.0706437825875019,0.10347590462662,13.6879120879121,"RELA"]
["GO:1900118","negative regulation of execution phase of apoptosis","biological_process",1,91,15,18684,0.0706437825875019,0.10347590462662,13.6879120879121,"BCL2L1"]
["GO:1901653","cellular response to peptide","biological_process",1,91,15,18684,0.0706437825875019,0.10347590462662,13.6879120879121,"KLF10"]
["GO:1902166","negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator","biological_process",1,91,15,18684,0.0706437825875019,0.10347590462662,13.6879120879121,"BCL2"]
["GO:1902230","negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage","biological_process",1,91,15,18684,0.0706437825875019,0.10347590462662,13.6879120879121,"BCL2L1"]
["GO:1903827","regulation of cellular protein localization","biological_process",1,91,15,18684,0.0706437825875019,0.10347590462662,13.6879120879121,"CCNE1"]
["GO:0007160","cell-matrix adhesion","biological_process",2,91,92,18684,0.0741086291463057,0.107692203441857,4.46344959388438,"VCAM1;BCL2L11"]
["GO:0046718","viral entry into host cell","biological_process",2,91,92,18684,0.0741086291463057,0.107692203441857,4.46344959388438,"CD80;BSG"]
["GO:0006309","apoptotic DNA fragmentation","biological_process",1,91,16,18684,0.0751738278917243,0.107692203441857,12.8324175824176,"CASP3"]
["GO:0006473","protein acetylation","biological_process",1,91,16,18684,0.0751738278917243,0.107692203441857,12.8324175824176,"FOXO1"]
["GO:0007093","mitotic cell cycle checkpoint","biological_process",1,91,16,18684,0.0751738278917243,0.107692203441857,12.8324175824176,"BCL2L1"]
["GO:0007413","axonal fasciculation","biological_process",1,91,16,18684,0.0751738278917243,0.107692203441857,12.8324175824176,"CASP3"]
["GO:0010633","negative regulation of epithelial cell migration","biological_process",1,91,16,18684,0.0751738278917243,0.107692203441857,12.8324175824176,"ADIPOR1"]
["GO:0010765","positive regulation of sodium ion transport","biological_process",1,91,16,18684,0.0751738278917243,0.107692203441857,12.8324175824176,"AKT1"]
["GO:0015909","long-chain fatty acid transport","biological_process",1,91,16,18684,0.0751738278917243,0.107692203441857,12.8324175824176,"PPARG"]
["GO:0031103","axon regeneration","biological_process",1,91,16,18684,0.0751738278917243,0.107692203441857,12.8324175824176,"BCL2"]
["GO:0042554","superoxide anion generation","biological_process",1,91,16,18684,0.0751738278917243,0.107692203441857,12.8324175824176,"EDN1"]
["GO:0045779","negative regulation of bone resorption","biological_process",1,91,16,18684,0.0751738278917243,0.107692203441857,12.8324175824176,"IL6"]
["GO:0050995","negative regulation of lipid catabolic process","biological_process",1,91,16,18684,0.0751738278917243,0.107692203441857,12.8324175824176,"IL1B"]
["GO:0051896","regulation of protein kinase B signaling","biological_process",1,91,16,18684,0.0751738278917243,0.107692203441857,12.8324175824176,"NTRK1"]
["GO:0060047","heart contraction","biological_process",1,91,16,18684,0.0751738278917243,0.107692203441857,12.8324175824176,"CDC42"]
["GO:0070050","neuron cellular homeostasis","biological_process",1,91,16,18684,0.0751738278917243,0.107692203441857,12.8324175824176,"IL6"]
["GO:0071375","cellular response to peptide hormone stimulus","biological_process",1,91,16,18684,0.0751738278917243,0.107692203441857,12.8324175824176,"EDN1"]
["GO:0090336","positive regulation of brown fat cell differentiation","biological_process",1,91,16,18684,0.0751738278917243,0.107692203441857,12.8324175824176,"PTGS2"]
["GO:0090399","replicative senescence","biological_process",1,91,16,18684,0.0751738278917243,0.107692203441857,12.8324175824176,"CDKN1A"]
["GO:1903146","regulation of autophagy of mitochondrion","biological_process",1,91,16,18684,0.0751738278917243,0.107692203441857,12.8324175824176,"SREBF1"]
["GO:2000010","positive regulation of protein localization to cell surface","biological_process",1,91,16,18684,0.0751738278917243,0.107692203441857,12.8324175824176,"AKT1"]
["GO:0070374","positive regulation of ERK1 and ERK2 cascade","biological_process",3,91,202,18684,0.0758969221863097,0.108645783387064,3.04928734631705,"MAPK3;NTRK1;CFLAR"]
["GO:0002407","dendritic cell chemotaxis","biological_process",1,91,17,18684,0.0796820334660687,0.112028792032964,12.0775694893342,"CCR2"]
["GO:0003203","endocardial cushion morphogenesis","biological_process",1,91,17,18684,0.0796820334660687,0.112028792032964,12.0775694893342,"NOS3"]
["GO:0016126","sterol biosynthetic process","biological_process",1,91,17,18684,0.0796820334660687,0.112028792032964,12.0775694893342,"PRKAG2"]
["GO:0031643","positive regulation of myelination","biological_process",1,91,17,18684,0.0796820334660687,0.112028792032964,12.0775694893342,"HGF"]
["GO:0032695","negative regulation of interleukin-12 production","biological_process",1,91,17,18684,0.0796820334660687,0.112028792032964,12.0775694893342,"IL10"]
["GO:0042176","regulation of protein catabolic process","biological_process",1,91,17,18684,0.0796820334660687,0.112028792032964,12.0775694893342,"ODC1"]
["GO:0042474","middle ear morphogenesis","biological_process",1,91,17,18684,0.0796820334660687,0.112028792032964,12.0775694893342,"EDN1"]
["GO:0045198","establishment of epithelial cell apical/basal polarity","biological_process",1,91,17,18684,0.0796820334660687,0.112028792032964,12.0775694893342,"CDC42"]
["GO:0048384","retinoic acid receptor signaling pathway","biological_process",1,91,17,18684,0.0796820334660687,0.112028792032964,12.0775694893342,"PPARG"]
["GO:0050870","positive regulation of T cell activation","biological_process",1,91,17,18684,0.0796820334660687,0.112028792032964,12.0775694893342,"CCR2"]
["GO:0051298","centrosome duplication","biological_process",1,91,17,18684,0.0796820334660687,0.112028792032964,12.0775694893342,"BRCA2"]
["GO:0060384","innervation","biological_process",1,91,17,18684,0.0796820334660687,0.112028792032964,12.0775694893342,"VCAM1"]
["GO:0070593","dendrite self-avoidance","biological_process",1,91,17,18684,0.0796820334660687,0.112028792032964,12.0775694893342,"BSG"]
["GO:0071404","cellular response to low-density lipoprotein particle stimulus","biological_process",1,91,17,18684,0.0796820334660687,0.112028792032964,12.0775694893342,"PPARG"]
["GO:0071850","mitotic cell cycle arrest","biological_process",1,91,17,18684,0.0796820334660687,0.112028792032964,12.0775694893342,"CDKN1A"]
["GO:0090190","positive regulation of branching involved in ureteric bud morphogenesis","biological_process",1,91,17,18684,0.0796820334660687,0.112028792032964,12.0775694893342,"VEGFA"]
["GO:2000811","negative regulation of anoikis","biological_process",1,91,17,18684,0.0796820334660687,0.112028792032964,12.0775694893342,"BCL2"]
["GO:0050830","defense response to Gram-positive bacterium","biological_process",2,91,99,18684,0.084055503064238,0.116346959064399,4.14785214785215,"IL6;CRP"]
["GO:0007221","positive regulation of transcription of Notch receptor target","biological_process",1,91,18,18684,0.0841685034373864,0.116346959064399,11.4065934065934,"STAT1"]
["GO:0007263","nitric oxide mediated signal transduction","biological_process",1,91,18,18684,0.0841685034373864,0.116346959064399,11.4065934065934,"NOS3"]
["GO:0008053","mitochondrial fusion","biological_process",1,91,18,18684,0.0841685034373864,0.116346959064399,11.4065934065934,"BAX"]
["GO:0009948","anterior/posterior axis specification","biological_process",1,91,18,18684,0.0841685034373864,0.116346959064399,11.4065934065934,"DDIT3"]
["GO:0010744","positive regulation of macrophage derived foam cell differentiation","biological_process",1,91,18,18684,0.0841685034373864,0.116346959064399,11.4065934065934,"AGTR1"]
["GO:0030279","negative regulation of ossification","biological_process",1,91,18,18684,0.0841685034373864,0.116346959064399,11.4065934065934,"BCL2"]
["GO:0030837","negative regulation of actin filament polymerization","biological_process",1,91,18,18684,0.0841685034373864,0.116346959064399,11.4065934065934,"PRKCD"]
["GO:0032717","negative regulation of interleukin-8 production","biological_process",1,91,18,18684,0.0841685034373864,0.116346959064399,11.4065934065934,"IL10"]
["GO:0032740","positive regulation of interleukin-17 production","biological_process",1,91,18,18684,0.0841685034373864,0.116346959064399,11.4065934065934,"IL6"]
["GO:0034329","cell junction assembly","biological_process",1,91,18,18684,0.0841685034373864,0.116346959064399,11.4065934065934,"CDC42"]
["GO:0042326","negative regulation of phosphorylation","biological_process",1,91,18,18684,0.0841685034373864,0.116346959064399,11.4065934065934,"CDKN1A"]
["GO:0043032","positive regulation of macrophage activation","biological_process",1,91,18,18684,0.0841685034373864,0.116346959064399,11.4065934065934,"IL10"]
["GO:0045638","negative regulation of myeloid cell differentiation","biological_process",1,91,18,18684,0.0841685034373864,0.116346959064399,11.4065934065934,"NFKBIA"]
["GO:0046470","phosphatidylcholine metabolic process","biological_process",1,91,18,18684,0.0841685034373864,0.116346959064399,11.4065934065934,"PON1"]
["GO:0061028","establishment of endothelial barrier","biological_process",1,91,18,18684,0.0841685034373864,0.116346959064399,11.4065934065934,"PECAM1"]
["GO:1903077","negative regulation of protein localization to plasma membrane","biological_process",1,91,18,18684,0.0841685034373864,0.116346959064399,11.4065934065934,"BCL2L1"]
["GO:0001649","osteoblast differentiation","biological_process",2,91,101,18684,0.0869689109623721,0.119954931166919,4.06571646175607,"AKT1;CAT"]
["GO:0005978","glycogen biosynthetic process","biological_process",1,91,19,18684,0.0886333414416292,0.120753349183084,10.8062463851938,"AKT1"]
["GO:0006883","cellular sodium ion homeostasis","biological_process",1,91,19,18684,0.0886333414416292,0.120753349183084,10.8062463851938,"IL1A"]
["GO:0007194","negative regulation of adenylate cyclase activity","biological_process",1,91,19,18684,0.0886333414416292,0.120753349183084,10.8062463851938,"CCR2"]
["GO:0008585","female gonad development","biological_process",1,91,19,18684,0.0886333414416292,0.120753349183084,10.8062463851938,"BRCA2"]
["GO:0010460","positive regulation of heart rate","biological_process",1,91,19,18684,0.0886333414416292,0.120753349183084,10.8062463851938,"EDN1"]
["GO:0010613","positive regulation of cardiac muscle hypertrophy","biological_process",1,91,19,18684,0.0886333414416292,0.120753349183084,10.8062463851938,"EDN1"]
["GO:0014911","positive regulation of smooth muscle cell migration","biological_process",1,91,19,18684,0.0886333414416292,0.120753349183084,10.8062463851938,"BCL2"]
["GO:0032793","positive regulation of CREB transcription factor activity","biological_process",1,91,19,18684,0.0886333414416292,0.120753349183084,10.8062463851938,"VEGFA"]
["GO:0034142","toll-like receptor 4 signaling pathway","biological_process",1,91,19,18684,0.0886333414416292,0.120753349183084,10.8062463851938,"NFKBIA"]
["GO:0043277","apoptotic cell clearance","biological_process",1,91,19,18684,0.0886333414416292,0.120753349183084,10.8062463851938,"NR1H3"]
["GO:0046827","positive regulation of protein export from nucleus","biological_process",1,91,19,18684,0.0886333414416292,0.120753349183084,10.8062463851938,"IL1B"]
["GO:0048514","blood vessel morphogenesis","biological_process",1,91,19,18684,0.0886333414416292,0.120753349183084,10.8062463851938,"CYP1B1"]
["GO:0060997","dendritic spine morphogenesis","biological_process",1,91,19,18684,0.0886333414416292,0.120753349183084,10.8062463851938,"CDC42"]
["GO:0070584","mitochondrion morphogenesis","biological_process",1,91,19,18684,0.0886333414416292,0.120753349183084,10.8062463851938,"BAX"]
["GO:1900016","negative regulation of cytokine production involved in inflammatory response","biological_process",1,91,19,18684,0.0886333414416292,0.120753349183084,10.8062463851938,"PPARA"]
["GO:2000251","positive regulation of actin cytoskeleton reorganization","biological_process",1,91,19,18684,0.0886333414416292,0.120753349183084,10.8062463851938,"CDC42"]
["GO:0051301","cell division","biological_process",4,91,349,18684,0.0908370360466648,0.123666547994416,2.35322270852357,"CCND1;BIRC5;CCNB1;CCNE1"]
["GO:0001678","cellular glucose homeostasis","biological_process",1,91,20,18684,0.0930766506261355,0.125809825828465,10.2659340659341,"FOXO1"]
["GO:0006693","prostaglandin metabolic process","biological_process",1,91,20,18684,0.0930766506261355,0.125809825828465,10.2659340659341,"PTGES"]
["GO:0030318","melanocyte differentiation","biological_process",1,91,20,18684,0.0930766506261355,0.125809825828465,10.2659340659341,"BCL2"]
["GO:0034063","stress granule assembly","biological_process",1,91,20,18684,0.0930766506261355,0.125809825828465,10.2659340659341,"EIF2S1"]
["GO:0042157","lipoprotein metabolic process","biological_process",1,91,20,18684,0.0930766506261355,0.125809825828465,10.2659340659341,"PPARA"]
["GO:0046847","filopodium assembly","biological_process",1,91,20,18684,0.0930766506261355,0.125809825828465,10.2659340659341,"CDC42"]
["GO:0090026","positive regulation of monocyte chemotaxis","biological_process",1,91,20,18684,0.0930766506261355,0.125809825828465,10.2659340659341,"CCR2"]
["GO:0044267","cellular protein metabolic process","biological_process",3,91,221,18684,0.0933315836941906,0.126064303404082,2.78713142061558,"MMP2;IL6;PAPPA"]
["GO:0043410","positive regulation of MAPK cascade","biological_process",2,91,108,18684,0.0973978510580251,0.129655223020927,3.8021978021978,"IL6;NTRK1"]
["GO:0006090","pyruvate metabolic process","biological_process",1,91,21,18684,0.0974985336519083,0.129655223020927,9.77708006279435,"BSG"]
["GO:0007095","mitotic G2 DNA damage checkpoint","biological_process",1,91,21,18684,0.0974985336519083,0.129655223020927,9.77708006279435,"CDKN1A"]
["GO:0009235","cobalamin metabolic process","biological_process",1,91,21,18684,0.0974985336519083,0.129655223020927,9.77708006279435,"CD320"]
["GO:0030879","mammary gland development","biological_process",1,91,21,18684,0.0974985336519083,0.129655223020927,9.77708006279435,"BCL2L11"]
["GO:0031293","membrane protein intracellular domain proteolysis","biological_process",1,91,21,18684,0.0974985336519083,0.129655223020927,9.77708006279435,"RELA"]
["GO:0042755","eating behavior","biological_process",1,91,21,18684,0.0974985336519083,0.129655223020927,9.77708006279435,"STAT3"]
["GO:0043254","regulation of protein-containing complex assembly","biological_process",1,91,21,18684,0.0974985336519083,0.129655223020927,9.77708006279435,"TRAF2"]
["GO:0043537","negative regulation of blood vessel endothelial cell migration","biological_process",1,91,21,18684,0.0974985336519083,0.129655223020927,9.77708006279435,"PPARG"]
["GO:0045995","regulation of embryonic development","biological_process",1,91,21,18684,0.0974985336519083,0.129655223020927,9.77708006279435,"NFE2L2"]
["GO:0048754","branching morphogenesis of an epithelial tube","biological_process",1,91,21,18684,0.0974985336519083,0.129655223020927,9.77708006279435,"VEGFA"]
["GO:0048844","artery morphogenesis","biological_process",1,91,21,18684,0.0974985336519083,0.129655223020927,9.77708006279435,"VEGFA"]
["GO:0051899","membrane depolarization","biological_process",1,91,21,18684,0.0974985336519083,0.129655223020927,9.77708006279435,"EDN1"]
["GO:0071542","dopaminergic neuron differentiation","biological_process",1,91,21,18684,0.0974985336519083,0.129655223020927,9.77708006279435,"VEGFA"]
["GO:1904886","beta-catenin destruction complex disassembly","biological_process",1,91,21,18684,0.0974985336519083,0.129655223020927,9.77708006279435,"CTNNB1"]
["GO:1990138","neuron projection extension","biological_process",1,91,21,18684,0.0974985336519083,0.129655223020927,9.77708006279435,"CTNNB1"]
["GO:2001235","positive regulation of apoptotic signaling pathway","biological_process",1,91,21,18684,0.0974985336519083,0.129655223020927,9.77708006279435,"PRKCD"]
["GO:0009615","response to virus","biological_process",2,91,109,18684,0.0989157770244372,0.131447459137885,3.76731525355379,"ODC1;CYP1A1"]
["GO:0007088","regulation of mitotic nuclear division","biological_process",1,91,22,18684,0.101899092695881,0.133720460990917,9.33266733266733,"CDC42"]
["GO:0008361","regulation of cell size","biological_process",1,91,22,18684,0.101899092695881,0.133720460990917,9.33266733266733,"MTOR"]
["GO:0010499","proteasomal ubiquitin-independent protein catabolic process","biological_process",1,91,22,18684,0.101899092695881,0.133720460990917,9.33266733266733,"NFE2L2"]
["GO:0014032","neural crest cell development","biological_process",1,91,22,18684,0.101899092695881,0.133720460990917,9.33266733266733,"EDN1"]
["GO:0030031","cell projection assembly","biological_process",1,91,22,18684,0.101899092695881,0.133720460990917,9.33266733266733,"CDC42"]
["GO:0032727","positive regulation of interferon-alpha production","biological_process",1,91,22,18684,0.101899092695881,0.133720460990917,9.33266733266733,"STAT1"]
["GO:0034622","cellular protein-containing complex assembly","biological_process",1,91,22,18684,0.101899092695881,0.133720460990917,9.33266733266733,"TRAF2"]
["GO:0035458","cellular response to interferon-beta","biological_process",1,91,22,18684,0.101899092695881,0.133720460990917,9.33266733266733,"STAT1"]
["GO:0035584","calcium-mediated signaling using intracellular calcium source","biological_process",1,91,22,18684,0.101899092695881,0.133720460990917,9.33266733266733,"VCAM1"]
["GO:0043401","steroid hormone mediated signaling pathway","biological_process",1,91,22,18684,0.101899092695881,0.133720460990917,9.33266733266733,"PPARA"]
["GO:0071901","negative regulation of protein serine/threonine kinase activity","biological_process",1,91,22,18684,0.101899092695881,0.133720460990917,9.33266733266733,"AKT1"]
["GO:0002223","stimulatory C-type lectin receptor signaling pathway","biological_process",2,91,113,18684,0.105053634536376,0.137566462366296,3.63395896139259,"RELA;PRKCD"]
["GO:0043488","regulation of mRNA stability","biological_process",2,91,113,18684,0.105053634536376,0.137566462366296,3.63395896139259,"AKT1;PRKCD"]
["GO:0001816","cytokine production","biological_process",1,91,23,18684,0.106278429453178,0.137652404175315,8.92689918776875,"CD28"]
["GO:0007141","male meiosis I","biological_process",1,91,23,18684,0.106278429453178,0.137652404175315,8.92689918776875,"BRCA2"]
["GO:0008643","carbohydrate transport","biological_process",1,91,23,18684,0.106278429453178,0.137652404175315,8.92689918776875,"AKT1"]
["GO:0016125","sterol metabolic process","biological_process",1,91,23,18684,0.106278429453178,0.137652404175315,8.92689918776875,"CYP1B1"]
["GO:0043393","regulation of protein binding","biological_process",1,91,23,18684,0.106278429453178,0.137652404175315,8.92689918776875,"CDC42"]
["GO:0045662","negative regulation of myoblast differentiation","biological_process",1,91,23,18684,0.106278429453178,0.137652404175315,8.92689918776875,"DDIT3"]
["GO:0045672","positive regulation of osteoclast differentiation","biological_process",1,91,23,18684,0.106278429453178,0.137652404175315,8.92689918776875,"KLF10"]
["GO:0051000","positive regulation of nitric-oxide synthase activity","biological_process",1,91,23,18684,0.106278429453178,0.137652404175315,8.92689918776875,"AKT1"]
["GO:0060135","maternal process involved in female pregnancy","biological_process",1,91,23,18684,0.106278429453178,0.137652404175315,8.92689918776875,"MTOR"]
["GO:0060999","positive regulation of dendritic spine development","biological_process",1,91,23,18684,0.106278429453178,0.137652404175315,8.92689918776875,"MTOR"]
["GO:0071157","negative regulation of cell cycle arrest","biological_process",1,91,23,18684,0.106278429453178,0.137652404175315,8.92689918776875,"CCND1"]
["GO:0090316","positive regulation of intracellular protein transport","biological_process",1,91,23,18684,0.106278429453178,0.137652404175315,8.92689918776875,"CDC42"]
["GO:0030336","negative regulation of cell migration","biological_process",2,91,116,18684,0.109723744553523,0.1416297617411,3.5399772641152,"BCL2;CYP1B1"]
["GO:0001656","metanephros development","biological_process",1,91,24,18684,0.110636645139356,0.141743831950219,8.55494505494506,"BCL2"]
["GO:0022604","regulation of cell morphogenesis","biological_process",1,91,24,18684,0.110636645139356,0.141743831950219,8.55494505494506,"SPARC"]
["GO:0031954","positive regulation of protein autophosphorylation","biological_process",1,91,24,18684,0.110636645139356,0.141743831950219,8.55494505494506,"VEGFA"]
["GO:0032753","positive regulation of interleukin-4 production","biological_process",1,91,24,18684,0.110636645139356,0.141743831950219,8.55494505494506,"CD28"]
["GO:0042311","vasodilation","biological_process",1,91,24,18684,0.110636645139356,0.141743831950219,8.55494505494506,"NOS3"]
["GO:0042832","defense response to protozoan","biological_process",1,91,24,18684,0.110636645139356,0.141743831950219,8.55494505494506,"IL10"]
["GO:0051602","response to electrical stimulus","biological_process",1,91,24,18684,0.110636645139356,0.141743831950219,8.55494505494506,"NTRK1"]
["GO:0072332","intrinsic apoptotic signaling pathway by p53 class mediator","biological_process",1,91,24,18684,0.110636645139356,0.141743831950219,8.55494505494506,"BAX"]
["GO:1904659","glucose transmembrane transport","biological_process",1,91,24,18684,0.110636645139356,0.141743831950219,8.55494505494506,"SLC2A4"]
["GO:0006911","phagocytosis, engulfment","biological_process",1,91,25,18684,0.114973840492642,0.146506423430988,8.21274725274725,"CDC42"]
["GO:0009060","aerobic respiration","biological_process",1,91,25,18684,0.114973840492642,0.146506423430988,8.21274725274725,"CAT"]
["GO:0048662","negative regulation of smooth muscle cell proliferation","biological_process",1,91,25,18684,0.114973840492642,0.146506423430988,8.21274725274725,"PPARG"]
["GO:0051894","positive regulation of focal adhesion assembly","biological_process",1,91,25,18684,0.114973840492642,0.146506423430988,8.21274725274725,"VEGFA"]
["GO:0051924","regulation of calcium ion transport","biological_process",1,91,25,18684,0.114973840492642,0.146506423430988,8.21274725274725,"BCL2"]
["GO:0071158","positive regulation of cell cycle arrest","biological_process",1,91,25,18684,0.114973840492642,0.146506423430988,8.21274725274725,"BRCA1"]
["GO:0001662","behavioral fear response","biological_process",1,91,26,18684,0.119290115776161,0.15058585376016,7.89687235841082,"BCL2"]
["GO:0006306","DNA methylation","biological_process",1,91,26,18684,0.119290115776161,0.15058585376016,7.89687235841082,"CYP1A1"]
["GO:0006694","steroid biosynthetic process","biological_process",1,91,26,18684,0.119290115776161,0.15058585376016,7.89687235841082,"CYP1A1"]
["GO:0007129","homologous chromosome pairing at meiosis","biological_process",1,91,26,18684,0.119290115776161,0.15058585376016,7.89687235841082,"CCNE1"]
["GO:0007498","mesoderm development","biological_process",1,91,26,18684,0.119290115776161,0.15058585376016,7.89687235841082,"VEGFA"]
["GO:0010033","response to organic substance","biological_process",1,91,26,18684,0.119290115776161,0.15058585376016,7.89687235841082,"RELA"]
["GO:0017144","drug metabolic process","biological_process",1,91,26,18684,0.119290115776161,0.15058585376016,7.89687235841082,"CYP1A1"]
["GO:0046329","negative regulation of JNK cascade","biological_process",1,91,26,18684,0.119290115776161,0.15058585376016,7.89687235841082,"AKT1"]
["GO:0050873","brown fat cell differentiation","biological_process",1,91,26,18684,0.119290115776161,0.15058585376016,7.89687235841082,"SLC2A4"]
["GO:0005977","glycogen metabolic process","biological_process",1,91,27,18684,0.123585570780147,0.154461542858729,7.60439560439561,"PRKAG2"]
["GO:0006754","ATP biosynthetic process","biological_process",1,91,27,18684,0.123585570780147,0.154461542858729,7.60439560439561,"PRKAG2"]
["GO:0009966","regulation of signal transduction","biological_process",1,91,27,18684,0.123585570780147,0.154461542858729,7.60439560439561,"PTPN1"]
["GO:0031069","hair follicle morphogenesis","biological_process",1,91,27,18684,0.123585570780147,0.154461542858729,7.60439560439561,"BCL2"]
["GO:0034113","heterotypic cell-cell adhesion","biological_process",1,91,27,18684,0.123585570780147,0.154461542858729,7.60439560439561,"VCAM1"]
["GO:0035307","positive regulation of protein dephosphorylation","biological_process",1,91,27,18684,0.123585570780147,0.154461542858729,7.60439560439561,"PRKCD"]
["GO:0035329","hippo signaling","biological_process",1,91,27,18684,0.123585570780147,0.154461542858729,7.60439560439561,"CASP3"]
["GO:0048255","mRNA stabilization","biological_process",1,91,27,18684,0.123585570780147,0.154461542858729,7.60439560439561,"MTOR"]
["GO:0050690","regulation of defense response to virus by virus","biological_process",1,91,27,18684,0.123585570780147,0.154461542858729,7.60439560439561,"CD28"]
["GO:0060828","regulation of canonical Wnt signaling pathway","biological_process",1,91,27,18684,0.123585570780147,0.154461542858729,7.60439560439561,"CTNNB1"]
["GO:0007015","actin filament organization","biological_process",2,91,127,18684,0.127293139810062,0.158028651256517,3.23336506013671,"BCL2;CDC42"]
["GO:0007205","protein kinase C-activating G protein-coupled receptor signaling pathway","biological_process",1,91,28,18684,0.127860304824152,0.158028651256517,7.33281004709576,"EDN1"]
["GO:0007585","respiratory gaseous exchange by respiratory system","biological_process",1,91,28,18684,0.127860304824152,0.158028651256517,7.33281004709576,"EDN1"]
["GO:0043085","positive regulation of catalytic activity","biological_process",1,91,28,18684,0.127860304824152,0.158028651256517,7.33281004709576,"BCL2"]
["GO:0044344","cellular response to fibroblast growth factor stimulus","biological_process",1,91,28,18684,0.127860304824152,0.158028651256517,7.33281004709576,"CXCL8"]
["GO:0045740","positive regulation of DNA replication","biological_process",1,91,28,18684,0.127860304824152,0.158028651256517,7.33281004709576,"CDC42"]
["GO:0045930","negative regulation of mitotic cell cycle","biological_process",1,91,28,18684,0.127860304824152,0.158028651256517,7.33281004709576,"IL10"]
["GO:0048041","focal adhesion assembly","biological_process",1,91,28,18684,0.127860304824152,0.158028651256517,7.33281004709576,"BCL2"]
["GO:0050832","defense response to fungus","biological_process",1,91,28,18684,0.127860304824152,0.158028651256517,7.33281004709576,"MPO"]
["GO:0051930","regulation of sensory perception of pain","biological_process",1,91,28,18684,0.127860304824152,0.158028651256517,7.33281004709576,"EDN1"]
["GO:0000083","regulation of transcription involved in G1/S transition of mitotic cell cycle","biological_process",1,91,29,18684,0.13211441675924,0.161800535330827,7.07995452823039,"CCNE1"]
["GO:0002218","activation of innate immune response","biological_process",1,91,29,18684,0.13211441675924,0.161800535330827,7.07995452823039,"XRCC6"]
["GO:0010803","regulation of tumor necrosis factor-mediated signaling pathway","biological_process",1,91,29,18684,0.13211441675924,0.161800535330827,7.07995452823039,"TRAF2"]
["GO:0034394","protein localization to cell surface","biological_process",1,91,29,18684,0.13211441675924,0.161800535330827,7.07995452823039,"CTNNB1"]
["GO:0040018","positive regulation of multicellular organism growth","biological_process",1,91,29,18684,0.13211441675924,0.161800535330827,7.07995452823039,"BCL2"]
["GO:0048008","platelet-derived growth factor receptor signaling pathway","biological_process",1,91,29,18684,0.13211441675924,0.161800535330827,7.07995452823039,"PLAT"]
["GO:0051281","positive regulation of release of sequestered calcium ion into cytosol","biological_process",1,91,29,18684,0.13211441675924,0.161800535330827,7.07995452823039,"BAX"]
["GO:0060325","face morphogenesis","biological_process",1,91,29,18684,0.13211441675924,0.161800535330827,7.07995452823039,"MMP2"]
["GO:0070328","triglyceride homeostasis","biological_process",1,91,29,18684,0.13211441675924,0.161800535330827,7.07995452823039,"NR1H3"]
["GO:0072593","reactive oxygen species metabolic process","biological_process",1,91,29,18684,0.13211441675924,0.161800535330827,7.07995452823039,"BCL2"]
["GO:0006413","translational initiation","biological_process",2,91,130,18684,0.132195572229576,0.161800535330827,3.15874894336433,"EIF6;EIF2S1"]
["GO:0008283","cell population proliferation","biological_process",2,91,130,18684,0.132195572229576,0.161800535330827,3.15874894336433,"AKT1;CYP1A1"]
["GO:0001818","negative regulation of cytokine production","biological_process",1,91,30,18684,0.13634800497017,0.165490421950316,6.84395604395604,"IL10"]
["GO:0006641","triglyceride metabolic process","biological_process",1,91,30,18684,0.13634800497017,0.165490421950316,6.84395604395604,"CAT"]
["GO:0019933","cAMP-mediated signaling","biological_process",1,91,30,18684,0.13634800497017,0.165490421950316,6.84395604395604,"AHR"]
["GO:0033077","T cell differentiation in thymus","biological_process",1,91,30,18684,0.13634800497017,0.165490421950316,6.84395604395604,"BCL2"]
["GO:0036151","phosphatidylcholine acyl-chain remodeling","biological_process",1,91,30,18684,0.13634800497017,0.165490421950316,6.84395604395604,"NR1H3"]
["GO:0042220","response to cocaine","biological_process",1,91,30,18684,0.13634800497017,0.165490421950316,6.84395604395604,"MTOR"]
["GO:0043392","negative regulation of DNA binding","biological_process",1,91,30,18684,0.13634800497017,0.165490421950316,6.84395604395604,"NFKBIA"]
["GO:0045907","positive regulation of vasoconstriction","biological_process",1,91,30,18684,0.13634800497017,0.165490421950316,6.84395604395604,"AKT1"]
["GO:0046579","positive regulation of Ras protein signal transduction","biological_process",1,91,30,18684,0.13634800497017,0.165490421950316,6.84395604395604,"NTRK1"]
["GO:0051491","positive regulation of filopodium assembly","biological_process",1,91,30,18684,0.13634800497017,0.165490421950316,6.84395604395604,"CDC42"]
["GO:0070372","regulation of ERK1 and ERK2 cascade","biological_process",1,91,30,18684,0.13634800497017,0.165490421950316,6.84395604395604,"IL1B"]
["GO:0000086","G2/M transition of mitotic cell cycle","biological_process",2,91,133,18684,0.137141052449352,0.1663462028106,3.08749896719822,"CDKN1A;CCNB1"]
["GO:0006629","lipid metabolic process","biological_process",2,91,135,18684,0.14046084122369,0.16940800988591,3.04175824175824,"PPARG;SREBF1"]
["GO:0002230","positive regulation of defense response to virus by host","biological_process",1,91,31,18684,0.140561167377574,0.16940800988591,6.62318326834456,"STAT1"]
["GO:0003180","aortic valve morphogenesis","biological_process",1,91,31,18684,0.140561167377574,0.16940800988591,6.62318326834456,"NOS3"]
["GO:0006270","DNA replication initiation","biological_process",1,91,31,18684,0.140561167377574,0.16940800988591,6.62318326834456,"CCNE1"]
["GO:0009953","dorsal/ventral pattern formation","biological_process",1,91,31,18684,0.140561167377574,0.16940800988591,6.62318326834456,"EDN1"]
["GO:0045739","positive regulation of DNA repair","biological_process",1,91,31,18684,0.140561167377574,0.16940800988591,6.62318326834456,"BRCA1"]
["GO:0071479","cellular response to ionizing radiation","biological_process",1,91,31,18684,0.140561167377574,0.16940800988591,6.62318326834456,"CDKN1A"]
["GO:0001657","ureteric bud development","biological_process",1,91,32,18684,0.144754001440119,0.173576294688183,6.41620879120879,"CAT"]
["GO:0006361","transcription initiation from RNA polymerase I promoter","biological_process",1,91,32,18684,0.144754001440119,0.173576294688183,6.41620879120879,"MAPK3"]
["GO:0007202","activation of phospholipase C activity","biological_process",1,91,32,18684,0.144754001440119,0.173576294688183,6.41620879120879,"SELE"]
["GO:0010043","response to zinc ion","biological_process",1,91,32,18684,0.144754001440119,0.173576294688183,6.41620879120879,"VCAM1"]
["GO:0010719","negative regulation of epithelial to mesenchymal transition","biological_process",1,91,32,18684,0.144754001440119,0.173576294688183,6.41620879120879,"ADIPOR1"]
["GO:0010975","regulation of neuron projection development","biological_process",1,91,32,18684,0.144754001440119,0.173576294688183,6.41620879120879,"AKT1"]
["GO:0015721","bile acid and bile salt transport","biological_process",1,91,32,18684,0.144754001440119,0.173576294688183,6.41620879120879,"NCOA2"]
["GO:0042113","B cell activation","biological_process",1,91,32,18684,0.144754001440119,0.173576294688183,6.41620879120879,"PRKCB"]
["GO:0042177","negative regulation of protein catabolic process","biological_process",1,91,33,18684,0.148926604156661,0.177790535644095,6.22177822177822,"RELA"]
["GO:1900182","positive regulation of protein localization to nucleus","biological_process",1,91,33,18684,0.148926604156661,0.177790535644095,6.22177822177822,"AKT1"]
["GO:0006958","complement activation, classical pathway","biological_process",1,91,34,18684,0.153079072068395,0.182172766067548,6.0387847446671,"CRP"]
["GO:0008015","blood circulation","biological_process",1,91,34,18684,0.153079072068395,0.182172766067548,6.0387847446671,"STAT1"]
["GO:0030100","regulation of endocytosis","biological_process",1,91,34,18684,0.153079072068395,0.182172766067548,6.0387847446671,"PTPN1"]
["GO:0001890","placenta development","biological_process",1,91,35,18684,0.157211501260983,0.186385853505059,5.86624803767661,"PPARG"]
["GO:0001942","hair follicle development","biological_process",1,91,35,18684,0.157211501260983,0.186385853505059,5.86624803767661,"RELA"]
["GO:0009409","response to cold","biological_process",1,91,35,18684,0.157211501260983,0.186385853505059,5.86624803767661,"PPARG"]
["GO:0043967","histone H4 acetylation","biological_process",1,91,35,18684,0.157211501260983,0.186385853505059,5.86624803767661,"BRCA2"]
["GO:0045540","regulation of cholesterol biosynthetic process","biological_process",1,91,35,18684,0.157211501260983,0.186385853505059,5.86624803767661,"SREBF1"]
["GO:0051209","release of sequestered calcium ion into cytosol","biological_process",1,91,35,18684,0.157211501260983,0.186385853505059,5.86624803767661,"DDIT3"]
["GO:0031333","negative regulation of protein-containing complex assembly","biological_process",1,91,36,18684,0.161323987366686,0.190545696508684,5.7032967032967,"CDC42"]
["GO:0001568","blood vessel development","biological_process",1,91,37,18684,0.165416625566473,0.19477138166015,5.54915354915355,"AHR"]
["GO:0006289","nucleotide-excision repair","biological_process",1,91,37,18684,0.165416625566473,0.19477138166015,5.54915354915355,"BRCA2"]
["GO:0007223","Wnt signaling pathway, calcium modulating pathway","biological_process",1,91,37,18684,0.165416625566473,0.19477138166015,5.54915354915355,"CTNNB1"]
["GO:0032722","positive regulation of chemokine production","biological_process",1,91,37,18684,0.165416625566473,0.19477138166015,5.54915354915355,"IL6"]
["GO:0098742","cell-cell adhesion via plasma-membrane adhesion molecules","biological_process",1,91,37,18684,0.165416625566473,0.19477138166015,5.54915354915355,"PECAM1"]
["GO:0006470","protein dephosphorylation","biological_process",2,91,150,18684,0.165872998343791,0.195187205891791,2.73758241758242,"BCL2;PTPN1"]
["GO:0006687","glycosphingolipid metabolic process","biological_process",1,91,39,18684,0.17354273672836,0.202698774029233,5.26458157227388,"BAX"]
["GO:0007257","activation of JUN kinase activity","biological_process",1,91,39,18684,0.17354273672836,0.202698774029233,5.26458157227388,"PTPN1"]
["GO:0009968","negative regulation of signal transduction","biological_process",1,91,39,18684,0.17354273672836,0.202698774029233,5.26458157227388,"PTPN1"]
["GO:0030030","cell projection organization","biological_process",1,91,39,18684,0.17354273672836,0.202698774029233,5.26458157227388,"AKT1"]
["GO:0032467","positive regulation of cytokinesis","biological_process",1,91,39,18684,0.17354273672836,0.202698774029233,5.26458157227388,"CDC42"]
["GO:0043010","camera-type eye development","biological_process",1,91,39,18684,0.17354273672836,0.202698774029233,5.26458157227388,"CYP1A1"]
["GO:0070317","negative regulation of G0 to G1 transition","biological_process",1,91,39,18684,0.17354273672836,0.202698774029233,5.26458157227388,"BRCA1"]
["GO:0032735","positive regulation of interleukin-12 production","biological_process",1,91,40,18684,0.177576397814856,0.207154206210915,5.13296703296703,"RELA"]
["GO:0061098","positive regulation of protein tyrosine kinase activity","biological_process",1,91,40,18684,0.177576397814856,0.207154206210915,5.13296703296703,"PTPN1"]
["GO:0003151","outflow tract morphogenesis","biological_process",1,91,41,18684,0.181590587248392,0.210280343225174,5.00777271508979,"VEGFA"]
["GO:0007098","centrosome cycle","biological_process",1,91,41,18684,0.181590587248392,0.210280343225174,5.00777271508979,"BRCA1"]
["GO:0009566","fertilization","biological_process",1,91,41,18684,0.181590587248392,0.210280343225174,5.00777271508979,"BAX"]
["GO:0009725","response to hormone","biological_process",1,91,41,18684,0.181590587248392,0.210280343225174,5.00777271508979,"NOS3"]
["GO:0030282","bone mineralization","biological_process",1,91,41,18684,0.181590587248392,0.210280343225174,5.00777271508979,"KLF10"]
["GO:0043966","histone H3 acetylation","biological_process",1,91,41,18684,0.181590587248392,0.210280343225174,5.00777271508979,"BRCA2"]
["GO:0048839","inner ear development","biological_process",1,91,41,18684,0.181590587248392,0.210280343225174,5.00777271508979,"SPARC"]
["GO:1900026","positive regulation of substrate adhesion-dependent cell spreading","biological_process",1,91,41,18684,0.181590587248392,0.210280343225174,5.00777271508979,"CDC42"]
["GO:0008542","visual learning","biological_process",1,91,42,18684,0.185585397984883,0.213989016822814,4.88854003139718,"MTOR"]
["GO:0031623","receptor internalization","biological_process",1,91,42,18684,0.185585397984883,0.213989016822814,4.88854003139718,"CXCL8"]
["GO:0060291","long-term synaptic potentiation","biological_process",1,91,42,18684,0.185585397984883,0.213989016822814,4.88854003139718,"MAPK1"]
["GO:2000300","regulation of synaptic vesicle exocytosis","biological_process",1,91,42,18684,0.185585397984883,0.213989016822814,4.88854003139718,"PRKCB"]
["GO:0007040","lysosome organization","biological_process",1,91,43,18684,0.189560922541442,0.217248305773253,4.77485305392282,"MTOR"]
["GO:0007080","mitotic metaphase plate congression","biological_process",1,91,43,18684,0.189560922541442,0.217248305773253,4.77485305392282,"CCNB1"]
["GO:0014070","response to organic cyclic compound","biological_process",1,91,43,18684,0.189560922541442,0.217248305773253,4.77485305392282,"PTGES"]
["GO:0021762","substantia nigra development","biological_process",1,91,43,18684,0.189560922541442,0.217248305773253,4.77485305392282,"CDC42"]
["GO:0034332","adherens junction organization","biological_process",1,91,43,18684,0.189560922541442,0.217248305773253,4.77485305392282,"CDC42"]
["GO:0042110","T cell activation","biological_process",1,91,43,18684,0.189560922541442,0.217248305773253,4.77485305392282,"CD28"]
["GO:0045596","negative regulation of cell differentiation","biological_process",1,91,43,18684,0.189560922541442,0.217248305773253,4.77485305392282,"MAPK1"]
["GO:0050766","positive regulation of phagocytosis","biological_process",1,91,43,18684,0.189560922541442,0.217248305773253,4.77485305392282,"IL1B"]
["GO:0060048","cardiac muscle contraction","biological_process",1,91,43,18684,0.189560922541442,0.217248305773253,4.77485305392282,"MTOR"]
["GO:0007156","homophilic cell adhesion via plasma membrane adhesion molecules","biological_process",2,91,165,18684,0.192013959911843,0.2196602529905,2.48871128871129,"PECAM1;BSG"]
["GO:0002548","monocyte chemotaxis","biological_process",1,91,44,18684,0.193517252998431,0.220712379626075,4.66633366633367,"IL6"]
["GO:0019827","stem cell population maintenance","biological_process",1,91,44,18684,0.193517252998431,0.220712379626075,4.66633366633367,"CTNNB1"]
["GO:0043124","negative regulation of I-kappaB kinase/NF-kappaB signaling","biological_process",1,91,44,18684,0.193517252998431,0.220712379626075,4.66633366633367,"STAT1"]
["GO:0070534","protein K63-linked ubiquitination","biological_process",1,91,44,18684,0.193517252998431,0.220712379626075,4.66633366633367,"TRAF2"]
["GO:0045087","innate immune response","biological_process",4,91,470,18684,0.196218789102103,0.223658667987991,1.74739303249942,"RELA;PPARG;XRCC6;CRP"]
["GO:0007519","skeletal muscle tissue development","biological_process",1,91,45,18684,0.197454481001497,0.224660904677395,4.56263736263736,"CFLAR"]
["GO:0045668","negative regulation of osteoblast differentiation","biological_process",1,91,45,18684,0.197454481001497,0.224660904677395,4.56263736263736,"PPARG"]
["GO:0030199","collagen fibril organization","biological_process",1,91,46,18684,0.201372697763601,0.228843612662842,4.46344959388438,"CYP1B1"]
["GO:0050714","positive regulation of protein secretion","biological_process",1,91,46,18684,0.201372697763601,0.228843612662842,4.46344959388438,"IL1A"]
["GO:0006986","response to unfolded protein","biological_process",1,91,47,18684,0.205271994067041,0.232855033461772,4.36848258124854,"DDIT3"]
["GO:0030218","erythrocyte differentiation","biological_process",1,91,47,18684,0.205271994067041,0.232855033461772,4.36848258124854,"CASP3"]
["GO:0030514","negative regulation of BMP signaling pathway","biological_process",1,91,47,18684,0.205271994067041,0.232855033461772,4.36848258124854,"PPARG"]
["GO:0030838","positive regulation of actin filament polymerization","biological_process",1,91,48,18684,0.209152460265458,0.236547429642333,4.27747252747253,"MTOR"]
["GO:0045785","positive regulation of cell adhesion","biological_process",1,91,48,18684,0.209152460265458,0.236547429642333,4.27747252747253,"VEGFA"]
["GO:0002931","response to ischemia","biological_process",1,91,49,18684,0.21301418628584,0.240339991805802,4.19017716976901,"BCL2"]
["GO:0007163","establishment or maintenance of cell polarity","biological_process",1,91,49,18684,0.21301418628584,0.240339991805802,4.19017716976901,"CDC42"]
["GO:0048856","anatomical structure development","biological_process",1,91,49,18684,0.21301418628584,0.240339991805802,4.19017716976901,"SPARC"]
["GO:0007052","mitotic spindle organization","biological_process",1,91,50,18684,0.216857261630514,0.243803259062605,4.10637362637363,"CCNB1"]
["GO:0007254","JNK cascade","biological_process",1,91,50,18684,0.216857261630514,0.243803259062605,4.10637362637363,"MAPK8"]
["GO:0030155","regulation of cell adhesion","biological_process",1,91,50,18684,0.216857261630514,0.243803259062605,4.10637362637363,"CXCL8"]
["GO:0035176","social behavior","biological_process",1,91,50,18684,0.216857261630514,0.243803259062605,4.10637362637363,"MTOR"]
["GO:0016567","protein ubiquitination","biological_process",4,91,494,18684,0.220523029607688,0.247661268392834,1.66249944387596,"AKT1;BRCA1;NFE2L2;CDC42"]
["GO:0006521","regulation of cellular amino acid metabolic process","biological_process",1,91,51,18684,0.220681775379125,0.247661268392834,4.02585649644473,"ODC1"]
["GO:0060041","retina development in camera-type eye","biological_process",1,91,52,18684,0.224487816190615,0.251038711068275,3.94843617920541,"BAX"]
["GO:0006897","endocytosis","biological_process",2,91,184,18684,0.22582111442418,0.252380453531989,2.23172479694219,"BCL2L1;CDC42"]
["GO:0050821","protein stabilization","biological_process",2,91,185,18684,0.227615007569872,0.254235073428605,2.21966141966142,"CDKN1A;PRKCD"]
["GO:0030216","keratinocyte differentiation","biological_process",1,91,53,18684,0.228275472305184,0.254371784401358,3.87393738337135,"CASP3"]
["GO:0071320","cellular response to cAMP","biological_process",1,91,53,18684,0.228275472305184,0.254371784401358,3.87393738337135,"AHR"]
["GO:0006006","glucose metabolic process","biological_process",1,91,54,18684,0.232044831546247,0.257509845336826,3.8021978021978,"AKT1"]
["GO:0007266","Rho protein signal transduction","biological_process",1,91,54,18684,0.232044831546247,0.257509845336826,3.8021978021978,"AGTR1"]
["GO:0051965","positive regulation of synapse assembly","biological_process",1,91,54,18684,0.232044831546247,0.257509845336826,3.8021978021978,"NTRK1"]
["GO:0071560","cellular response to transforming growth factor beta stimulus","biological_process",1,91,54,18684,0.232044831546247,0.257509845336826,3.8021978021978,"EDN1"]
["GO:1903078","positive regulation of protein localization to plasma membrane","biological_process",1,91,54,18684,0.232044831546247,0.257509845336826,3.8021978021978,"AKT1"]
["GO:0031532","actin cytoskeleton reorganization","biological_process",1,91,56,18684,0.239529008629245,0.264573221564195,3.66640502354788,"PTPN1"]
["GO:0032720","negative regulation of tumor necrosis factor production","biological_process",1,91,56,18684,0.239529008629245,0.264573221564195,3.66640502354788,"IL10"]
["GO:0036498","IRE1-mediated unfolded protein response","biological_process",1,91,56,18684,0.239529008629245,0.264573221564195,3.66640502354788,"PTPN1"]
["GO:0070830","bicellular tight junction assembly","biological_process",1,91,57,18684,0.243244000051553,0.268519792234376,3.60208212839792,"PECAM1"]
["GO:0006310","DNA recombination","biological_process",1,91,58,18684,0.246941041764942,0.271807630953146,3.5399772641152,"XRCC6"]
["GO:0021766","hippocampus development","biological_process",1,91,58,18684,0.246941041764942,0.271807630953146,3.5399772641152,"CASP3"]
["GO:0001570","vasculogenesis","biological_process",1,91,59,18684,0.250620219537915,0.275216512860742,3.47997764946917,"VEGFA"]
["GO:0010508","positive regulation of autophagy","biological_process",1,91,59,18684,0.250620219537915,0.275216512860742,3.47997764946917,"FOXO1"]
["GO:0060079","excitatory postsynaptic potential","biological_process",1,91,59,18684,0.250620219537915,0.275216512860742,3.47997764946917,"AKT1"]
["GO:0006879","cellular iron ion homeostasis","biological_process",1,91,60,18684,0.25428161873373,0.277945977471377,3.42197802197802,"MYC"]
["GO:0006909","phagocytosis","biological_process",1,91,60,18684,0.25428161873373,0.277945977471377,3.42197802197802,"PECAM1"]
["GO:0007193","adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway","biological_process",1,91,60,18684,0.25428161873373,0.277945977471377,3.42197802197802,"EDN1"]
["GO:0007200","phospholipase C-activating G protein-coupled receptor signaling pathway","biological_process",1,91,60,18684,0.25428161873373,0.277945977471377,3.42197802197802,"AGTR1"]
["GO:0032880","regulation of protein localization","biological_process",1,91,60,18684,0.25428161873373,0.277945977471377,3.42197802197802,"MAPK8"]
["GO:0034613","cellular protein localization","biological_process",1,91,60,18684,0.25428161873373,0.277945977471377,3.42197802197802,"CDC42"]
["GO:0022900","electron transport chain","biological_process",1,91,61,18684,0.257925324312297,0.281603226486463,3.36588002161773,"XDH"]
["GO:0006417","regulation of translation","biological_process",1,91,63,18684,0.265159992451881,0.289168134790373,3.25902668759812,"AKT1"]
["GO:0048208","COPII vesicle coating","biological_process",1,91,64,18684,0.26875112293289,0.292746758909041,3.2081043956044,"TGFA"]
["GO:0071300","cellular response to retinoic acid","biological_process",1,91,64,18684,0.26875112293289,0.292746758909041,3.2081043956044,"PPARG"]
["GO:0006625","protein targeting to peroxisome","biological_process",1,91,65,18684,0.272324895640361,0.296468841482972,3.15874894336433,"CAT"]
["GO:0016485","protein processing","biological_process",1,91,66,18684,0.275881393545551,0.299478596552605,3.11088911088911,"CASP3"]
["GO:0060070","canonical Wnt signaling pathway","biological_process",1,91,68,18684,0.282942894875087,0.306265033891694,3.01939237233355,"CTNNB1"]
["GO:0010506","regulation of autophagy","biological_process",1,91,69,18684,0.286448062288407,0.309527591878501,2.97563306258958,"DDIT3"]
["GO:0043087","regulation of GTPase activity","biological_process",1,91,69,18684,0.286448062288407,0.309527591878501,2.97563306258958,"MTOR"]
["GO:0061844","antimicrobial humoral immune response mediated by antimicrobial peptide","biological_process",1,91,69,18684,0.286448062288407,0.309527591878501,2.97563306258958,"CXCL8"]
["GO:0032508","DNA duplex unwinding","biological_process",1,91,70,18684,0.289936282881034,0.312760702183705,2.9331240188383,"XRCC6"]
["GO:0045652","regulation of megakaryocyte differentiation","biological_process",1,91,70,18684,0.289936282881034,0.312760702183705,2.9331240188383,"EIF6"]
["GO:0070373","negative regulation of ERK1 and ERK2 cascade","biological_process",1,91,70,18684,0.289936282881034,0.312760702183705,2.9331240188383,"PTPN1"]
["GO:0007265","Ras protein signal transduction","biological_process",1,91,71,18684,0.293407637681605,0.315425720782214,2.89181241293917,"CDKN1A"]
["GO:0031398","positive regulation of protein ubiquitination","biological_process",1,91,71,18684,0.293407637681605,0.315425720782214,2.89181241293917,"BRCA1"]
["GO:0033674","positive regulation of kinase activity","biological_process",1,91,71,18684,0.293407637681605,0.315425720782214,2.89181241293917,"NTRK1"]
["GO:0043433","negative regulation of DNA-binding transcription factor activity","biological_process",1,91,71,18684,0.293407637681605,0.315425720782214,2.89181241293917,"DDIT3"]
["GO:0061418","regulation of transcription from RNA polymerase II promoter in response to hypoxia","biological_process",1,91,71,18684,0.293407637681605,0.315425720782214,2.89181241293917,"VEGFA"]
["GO:0045732","positive regulation of protein catabolic process","biological_process",1,91,72,18684,0.296862207335662,0.318777077837443,2.85164835164835,"FOXO1"]
["GO:0035264","multicellular organism growth","biological_process",1,91,73,18684,0.300300072107447,0.321920315394094,2.81258467559837,"MTOR"]
["GO:0007409","axonogenesis","biological_process",1,91,74,18684,0.303721311881678,0.325035088154077,2.77457677457677,"BCL2"]
["GO:0006816","calcium ion transport","biological_process",1,91,75,18684,0.307126006165331,0.328121625795842,2.73758241758242,"PRKCB"]
["GO:0032436","positive regulation of proteasomal ubiquitin-dependent protein catabolic process","biological_process",1,91,75,18684,0.307126006165331,0.328121625795842,2.73758241758242,"AKT1"]
["GO:0030512","negative regulation of transforming growth factor beta receptor signaling pathway","biological_process",1,91,76,18684,0.310514234089397,0.331554159606466,2.70156159629844,"PPARA"]
["GO:0000902","cell morphogenesis","biological_process",1,91,77,18684,0.31388607441065,0.334776405364094,2.6664763807621,"HGF"]
["GO:0008544","epidermis development","biological_process",1,91,77,18684,0.31388607441065,0.334776405364094,2.6664763807621,"PPARA"]
["GO:0007283","spermatogenesis","biological_process",3,91,404,18684,0.314430662454353,0.335168197689504,1.52464367315852,"CCNB1;BCL2L11;BRCA2"]
["GO:0042632","cholesterol homeostasis","biological_process",1,91,79,18684,0.320580905411177,0.341339241065617,2.59897064960356,"NR1H3"]
["GO:1901990","regulation of mitotic cell cycle phase transition","biological_process",1,91,79,18684,0.320580905411177,0.341339241065617,2.59897064960356,"CCNB1"]
["GO:0006464","cellular protein modification process","biological_process",1,91,81,18684,0.327211121802927,0.34761586029738,2.53479853479854,"PLAT"]
["GO:0031145","anaphase-promoting complex-dependent catabolic process","biological_process",1,91,82,18684,0.330502192485932,0.350521394274199,2.50388635754489,"CCNB1"]
["GO:0050829","defense response to Gram-negative bacterium","biological_process",1,91,82,18684,0.330502192485932,0.350521394274199,2.50388635754489,"IL6"]
["GO:0071277","cellular response to calcium ion","biological_process",1,91,82,18684,0.330502192485932,0.350521394274199,2.50388635754489,"EDN1"]
["GO:0030509","BMP signaling pathway","biological_process",1,91,83,18684,0.333777340345505,0.353598291648936,2.47371905203231,"MAPK3"]
["GO:0150104","transport across blood-brain barrier","biological_process",1,91,84,18684,0.337036641567405,0.356641225982085,2.44427001569859,"SLC2A4"]
["GO:0030154","cell differentiation","biological_process",4,91,602,18684,0.337215500822828,0.356641225982085,1.36424372969223,"AKT1;PPARG;PPARA;NR1H3"]
["GO:0007005","mitochondrion organization","biological_process",1,91,87,18684,0.346720221868022,0.366079251564729,2.35998484274346,"NOS3"]
["GO:0060071","Wnt signaling pathway, planar cell polarity pathway","biological_process",1,91,89,18684,0.353098089476125,0.371982444122201,2.3069514754908,"CDC42"]
["GO:0016311","dephosphorylation","biological_process",1,91,90,18684,0.356263890705363,0.375108584256036,2.28131868131868,"PON1"]
["GO:0006338","chromatin remodeling","biological_process",1,91,91,18684,0.359414368598543,0.37800476697433,2.25624924526023,"MYC"]
["GO:0016236","macroautophagy","biological_process",1,91,94,18684,0.368774594016928,0.387418198492228,2.18424129062427,"PRKAG2"]
["GO:0001764","neuron migration","biological_process",1,91,95,18684,0.37186450859167,0.390230735708572,2.16124927703875,"BAX"]
["GO:0007229","integrin-mediated signaling pathway","biological_process",1,91,95,18684,0.37186450859167,0.390230735708572,2.16124927703875,"CDC42"]
["GO:0000209","protein polyubiquitination","biological_process",2,91,266,18684,0.37259283231018,0.390778172988658,1.54374948359911,"BCL2;CTNNB1"]
["GO:0030334","regulation of cell migration","biological_process",1,91,96,18684,0.374939463119517,0.39302135518792,2.13873626373626,"AKT1"]
["GO:0006898","receptor-mediated endocytosis","biological_process",1,91,99,18684,0.384075281019964,0.40148499525083,2.07392607392607,"SPARC"]
["GO:0035335","peptidyl-tyrosine dephosphorylation","biological_process",1,91,101,18684,0.390092330242275,0.407549500822178,2.03285823087803,"PTPN1"]
["GO:0007219","Notch signaling pathway","biological_process",1,91,102,18684,0.393079016888563,0.410216567845625,2.01292824822237,"MYC"]
["GO:0055085","transmembrane transport","biological_process",2,91,290,18684,0.413898180273873,0.43051785417926,1.41599090564608,"BCL2;EIF2S1"]
["GO:0007155","cell adhesion","biological_process",3,91,485,18684,0.421845341450456,0.438301945430117,1.27001246176504,"CTNNB1;VCAM1;CYP1B1"]
["GO:0031175","neuron projection development","biological_process",1,91,114,18684,0.427810515181087,0.444011901321314,1.80104106419896,"IL6"]
["GO:0007030","Golgi organization","biological_process",1,91,115,18684,0.430614459344712,0.446431986085992,1.78537983755375,"CDC42"]
["GO:0007186","G protein-coupled receptor signaling pathway","biological_process",6,91,1102,18684,0.450250952120262,0.465768353643006,1.11788755708901,"AKT1;EDN1;PPARG;CXCL8;AGTR1;CCR2"]
["GO:0007169","transmembrane receptor protein tyrosine kinase signaling pathway","biological_process",1,91,123,18684,0.452562201309915,0.467647608020245,1.6692575716966,"NTRK1"]
["GO:0001501","skeletal system development","biological_process",1,91,126,18684,0.460575076225524,0.475148646558901,1.62951334379906,"MMP9"]
["GO:0007399","nervous system development","biological_process",2,91,321,18684,0.465211976969879,0.479409181716643,1.27924412036562,"STAT3;VEGFA"]
["GO:0006914","autophagy","biological_process",1,91,128,18684,0.46585243718966,0.479546520808736,1.6040521978022,"FOXO1"]
["GO:0006260","DNA replication","biological_process",1,91,129,18684,0.468471936446814,0.481980648433583,1.59161768464094,"BRCA1"]
["GO:0006325","chromatin organization","biological_process",1,91,131,18684,0.473672878699845,0.487066565318873,1.5673181780052,"RELA"]
["GO:0000278","mitotic cell cycle","biological_process",1,91,132,18684,0.476254443300627,0.489454974066025,1.55544455544456,"HGF"]
["GO:0061024","membrane organization","biological_process",1,91,133,18684,0.47882348414041,0.491827924231133,1.54374948359911,"TGFA"]
["GO:0009887","animal organ morphogenesis","biological_process",1,91,134,18684,0.481380061303001,0.493917360783491,1.53222896506479,"RELA"]
["GO:0005975","carbohydrate metabolic process","biological_process",1,91,135,18684,0.483924234587175,0.496258529069603,1.52087912087912,"SLC2A4"]
["GO:0050776","regulation of immune response","biological_process",1,91,139,18684,0.493978075013708,0.506019794068755,1.47711281524231,"VCAM1"]
["GO:0051056","regulation of small GTPase mediated signal transduction","biological_process",1,91,141,18684,0.498932105998196,0.510817873547693,1.45616086041618,"CDC42"]
["GO:0010951","negative regulation of endopeptidase activity","biological_process",1,91,143,18684,0.503838164082507,0.515282838442413,1.43579497425651,"AKT1"]
["GO:0008360","regulation of cell shape","biological_process",1,91,145,18684,0.508696708705248,0.519689614349878,1.41599090564608,"VEGFA"]
["GO:0030182","neuron differentiation","biological_process",1,91,145,18684,0.508696708705248,0.519689614349878,1.41599090564608,"CASP3"]
["GO:0030036","actin cytoskeleton organization","biological_process",1,91,148,18684,0.515896432223135,0.525908438454959,1.38728838728839,"CDC42"]
["GO:0072659","protein localization to plasma membrane","biological_process",1,91,148,18684,0.515896432223135,0.525908438454959,1.38728838728839,"BSG"]
["GO:0006412","translation","biological_process",1,91,168,18684,0.561298538865594,0.569734587758904,1.22213500784929,"AKT1"]
["GO:0090090","negative regulation of canonical Wnt signaling pathway","biological_process",1,91,173,18684,0.571974597492178,0.580259637262719,1.18681318681319,"DDIT3"]
["GO:0002250","adaptive immune response","biological_process",1,91,178,18684,0.582393634105389,0.59019633552695,1.1534757377454,"PRKCB"]
["GO:0006888","endoplasmic reticulum to Golgi vesicle-mediated transport","biological_process",1,91,187,18684,0.600519649359137,0.607913627911204,1.09796086266674,"TGFA"]
["GO:0007601","visual perception","biological_process",1,91,204,18684,0.632660453879844,0.639081687119009,1.00646412411118,"CYP1B1"]
["GO:0050790","regulation of catalytic activity","biological_process",1,91,227,18684,0.67210892604112,0.678568061475578,0.90448758290168,"PRKAG2"]
["GO:0016477","cell migration","biological_process",1,91,231,18684,0.67852828608899,0.68468355869492,0.888825460254032,"CDC42"]
["GO:0007268","chemical synaptic transmission","biological_process",1,91,242,18684,0.695547627603138,0.701109042535999,0.848424302969758,"MAPK1"]
["GO:0043547","positive regulation of GTPase activity","biological_process",1,91,310,18684,0.782645075723057,0.787224382017181,0.662318326834456,"NTRK1"]
["GO:0015031","protein transport","biological_process",1,91,325,18684,0.798250097811802,0.801641494934742,0.631749788672866,"AAGAB"]
["GO:0043687","post-translational protein modification","biological_process",1,91,342,18684,0.81459946804969,0.817626111508473,0.600347021399653,"IL6"]
["GO:0007275","multicellular organism development","biological_process",1,91,481,18684,0.907374704759391,0.908816507786021,0.426857965319504,"NTRK1"]
["GO:0032991","protein-containing complex","cellular_component",20,91,635,18684,{"v":2.14876535841122e-11,"d":"2.15E-11"},{"v":3.12562714827355e-09,"d":"3.13E-09"},6.46673012027343,"NCOA2;AKT1;BCL2;CDKN1A;CASP9;MAPK3;MAPK1;CAT;STAT1;CTNNB1;MYC;BRCA1;XRCC6;PECAM1;PTPN1;AHR;NTRK1;SREBF1;CDC42;BRCA2"]
["GO:0005829","cytosol","cellular_component",52,91,5198,18684,{"v":3.99094008679387e-09,"d":"3.99E-09"},{"v":2.90264142466431e-07,"d":"2.90E-07"},2.05397680426538,"RELA;STAT3;AKT1;CCND1;BCL2;BCL2L1;CDKN1A;EIF6;BAX;CASP9;MAPK3;MAPK1;CASP3;MAPK8;NFKBIA;ODC1;XDH;CAT;STAT1;FOXO1;PPARG;CTNNB1;IL1B;PRKCD;XRCC6;PRKCB;BIRC5;NOS3;PTPN1;CCNB1;DDIT3;IL1A;NFE2L2;AHR;PRKAG2;SLC2A4;CCNE1;SREBF1;JAK1;IRS1;CFLAR;MTOR;CCR2;EIF2S1;BCL2L11;TNFRSF10A;TRAF2;CDC42;CD28;NR1H3;BRCA2;AAGAB"]
["GO:0005737","cytoplasm","cellular_component",46,91,4631,18684,{"v":1.01503541437976e-07,"d":"1.02E-07"},{"v":4.15586701307098e-06,"d":"4.16E-06"},2.03944274253063,"PTGS1;PTGS2;NCOA2;RELA;STAT3;AKT1;VEGFA;CCND1;BCL2;BCL2L1;EIF6;BAX;CASP9;MAPK3;MAPK1;CASP3;MAPK8;NFKBIA;ODC1;CAT;STAT1;EDN1;FOXO1;CTNNB1;PRKCD;BRCA1;PRKCB;BIRC5;NOS3;CCNB1;DDIT3;PLAT;NFE2L2;AHR;PRKAG2;CCNE1;SREBF1;JAK1;IRS1;CFLAR;MTOR;CCR2;CDC42;NR1H3;SPARC;AAGAB"]
["GO:0005615","extracellular space","cellular_component",23,91,1487,18684,{"v":4.74037181177519e-07,"d":"4.74E-07"},{"v":1.57263913966086e-05,"d":"1.57E-05"},3.17574288522506,"VEGFA;PLAU;MMP2;MMP9;IL10;IL6;XDH;EDN1;IL1B;SELE;VCAM1;CXCL8;PECAM1;HGF;PLAT;IL1A;MPO;PRKAG2;CRP;PON1;PAPPA;SPARC;TGFA"]
["GO:0097136","Bcl-2 family protein complex","cellular_component",3,91,6,18684,{"v":2.21184005652551e-06,"d":"2.21E-06"},{"v":5.1636907986293e-05,"d":"5.16E-05"},102.659340659341,"BCL2L1;BAX;BCL2L11"]
["GO:0005654","nucleoplasm","cellular_component",38,91,3787,18684,{"v":2.39491867743074e-06,"d":"2.39E-06"},{"v":5.47528886924623e-05,"d":"5.48E-05"},2.06023498550565,"NCOA2;RELA;STAT3;AKT1;CCND1;BCL2;CDKN1A;EIF6;MAPK3;MAPK1;CASP3;MAPK8;NFKBIA;STAT1;RUNX1T1;FOXO1;PPARG;CTNNB1;MYC;PRKCD;BRCA1;XRCC6;PRKCB;BIRC5;CCNB1;DDIT3;MPO;NFE2L2;AHR;PRKAG2;PPARA;CCNE1;SREBF1;IRS1;MTOR;TRAF2;NR1H3;BRCA2"]
["GO:0005576","extracellular region","cellular_component",23,91,1777,18684,{"v":9.87019069474656e-06,"d":"9.87E-06"},0.000154252319039386,2.6574730840347,"VEGFA;PLAU;MMP2;MMP9;MAPK1;IL10;IL6;CAT;EDN1;IL1B;PRKCD;CXCL8;XRCC6;HGF;PLAT;IL1A;MPO;CRP;PON1;TNFSF10;PAPPA;SPARC;TGFA"]
["GO:0000307","cyclin-dependent protein kinase holoenzyme complex","cellular_component",4,91,30,18684,{"v":1.30965090535153e-05,"d":"1.31E-05"},0.000198402109422526,27.3758241758242,"CCND1;CDKN1A;CCNB1;CCNE1"]
["GO:0045121","membrane raft","cellular_component",8,91,233,18684,{"v":1.81027859775298e-05,"d":"1.81E-05"},0.000251708590319918,7.04956845729378,"CASP3;SELE;PECAM1;SLC2A4;CFLAR;TNFRSF10A;TRAF2;BSG"]
["GO:0005901","caveola","cellular_component",5,91,75,18684,{"v":3.23586032884325e-05,"d":"3.24E-05"},0.000407934125456173,13.6879120879121,"MAPK3;MAPK1;SELE;NOS3;IRS1"]
["GO:0032993","protein-DNA complex","cellular_component",4,91,41,18684,{"v":4.64554516053517e-05,"d":"4.65E-05"},0.00054226703077605,20.0310908603592,"CTNNB1;XRCC6;DDIT3;NFE2L2"]
["GO:0005634","nucleus","cellular_component",43,91,5302,18684,{"v":9.89958658580871e-05,"d":"9.90E-05"},0.000985269380724435,1.66516471080786,"NCOA2;RELA;STAT3;AKT1;CCND1;BCL2;CDKN1A;EIF6;BAX;MMP2;MAPK3;MAPK1;CASP3;MAPK8;NFKBIA;STAT1;RUNX1T1;FOXO1;PPARG;CTNNB1;MYC;PRKCD;BRCA1;XRCC6;PRKCB;BIRC5;NOS3;CCNB1;DDIT3;MPO;NFE2L2;AHR;PRKAG2;PPARA;CCNE1;KLF10;SREBF1;JAK1;IRS1;MTOR;EIF2S1;NR1H3;BRCA2"]
["GO:0005741","mitochondrial outer membrane","cellular_component",6,91,169,18684,0.000176980047339866,0.00158611028208382,7.28942063853306,"BCL2;BCL2L1;BAX;BCL2A1;MTOR;BCL2L11"]
["GO:0000785","chromatin","cellular_component",14,91,943,18684,0.00017925992559715,0.00159896471369911,3.04820947875031,"NCOA2;RELA;STAT3;STAT1;FOXO1;PPARG;MYC;DDIT3;NFE2L2;AHR;PPARA;KLF10;SREBF1;NR1H3"]
["GO:0098636","protein complex involved in cell adhesion","cellular_component",2,91,5,18684,0.000232393738599392,0.0018621040664892,82.1274725274725,"CD80;CD28"]
["GO:0005667","transcription regulator complex","cellular_component",6,91,193,18684,0.000361743861104315,0.00262091050325004,6.38296418607299,"RELA;STAT3;CTNNB1;XRCC6;DDIT3;AHR"]
["GO:0012506","vesicle membrane","cellular_component",3,91,29,18684,0.000372594421277998,0.00265877754957243,21.2398635846912,"NOS3;SLC2A4;TRAF2"]
["GO:0009986","cell surface","cellular_component",10,91,572,18684,0.000464033632691353,0.00305671162646024,3.58948743564128,"VEGFA;PLAU;VCAM1;PLAT;CD80;NTRK1;TNFRSF10A;CD28;SPARC;TGFA"]
["GO:0031264","death-inducing signaling complex","cellular_component",2,91,7,18684,0.000484935741902735,0.00305671162646024,58.6624803767661,"CASP3;CFLAR"]
["GO:0048471","perinuclear region of cytoplasm","cellular_component",11,91,692,18684,0.000532159375946629,0.00333216350965257,3.26373626373626,"CDKN1A;ODC1;STAT1;PPARG;CTNNB1;SELE;PRKCD;SLC2A4;CCR2;PTGES;TGFA"]
["GO:0030141","secretory granule","cellular_component",4,91,83,18684,0.000721402201075401,0.00409661129799875,9.89487620812922,"VEGFA;MPO;CDC42;BRCA2"]
["GO:0005925","focal adhesion","cellular_component",8,91,419,18684,0.00100302076821399,0.00526864520192403,3.92016575310131,"PLAU;MAPK3;MAPK1;CAT;CTNNB1;JAK1;CDC42;BSG"]
["GO:0005739","mitochondrion","cellular_component",15,91,1281,18684,0.00126434767288541,0.00619399339229615,2.40420001544123,"AKT1;BCL2;BCL2L1;BAX;MMP2;MAPK3;MAPK1;MAPK8;CAT;FOXO1;PRKCD;CYP1B1;BCL2L11;BSG;SPARC"]
["GO:0005911","cell-cell junction","cellular_component",5,91,175,18684,0.00165354131673365,0.00758943356782364,5.86624803767661,"AKT1;CTNNB1;PRKCD;PECAM1;CDC42"]
["GO:0046930","pore complex","cellular_component",2,91,13,18684,0.00176722923276154,0.00790030846135244,31.5874894336433,"BCL2;BAX"]
["GO:0000800","lateral element","cellular_component",2,91,14,18684,0.00205524525827086,0.00885300406239223,29.331240188383,"BRCA1;BRCA2"]
["GO:0005789","endoplasmic reticulum membrane","cellular_component",12,91,958,18684,0.00231984569563273,0.00974850713431444,2.57184151964945,"PTGS1;PTGS2;BCL2;BAX;CYP1A1;CYP1B1;SREBF1;MTOR;PTGES;CDC42;BSG;TGFA"]
["GO:0031092","platelet alpha granule membrane","cellular_component",2,91,17,18684,0.00304253870222112,0.0119614151474016,24.1551389786684,"PECAM1;SPARC"]
["GO:1904813","ficolin-1-rich granule lumen","cellular_component",4,91,124,18684,0.00316592588930535,0.0123949603657897,6.62318326834456,"MMP9;MAPK1;CAT;XRCC6"]
["GO:0031143","pseudopodium","cellular_component",2,91,18,18684,0.00341204395366733,0.0129822436949395,22.8131868131868,"MAPK3;MAPK1"]
["GO:0031093","platelet alpha granule lumen","cellular_component",3,91,67,18684,0.00427521304715597,0.0155171360310402,9.19337379038872,"VEGFA;HGF;SPARC"]
["GO:0090575","RNA polymerase II transcription regulator complex","cellular_component",3,91,67,18684,0.00427521304715597,0.0155171360310402,9.19337379038872,"STAT3;PPARG;NR1H3"]
["GO:0005770","late endosome","cellular_component",4,91,136,18684,0.00440251229916445,0.0159485646699616,6.0387847446671,"MAPK3;MAPK1;DDIT3;NTRK1"]
["GO:0005886","plasma membrane","cellular_component",33,91,4445,18684,0.00501817249343676,0.0178794181050725,1.52430067120731,"STAT3;AKT1;PLAU;MMP2;MAPK3;MAPK1;NFKBIA;CAT;CTNNB1;SELE;VCAM1;PRKCD;BRCA1;PRKCB;PECAM1;NOS3;PTPN1;NFE2L2;SLC2A4;CD80;NTRK1;ADIPOR1;ADIPOR2;AGTR1;IRS1;CCR2;TNFRSF10A;CDC42;BSG;CD28;SPARC;TGFA;CD320"]
["GO:0070062","extracellular exosome","cellular_component",19,91,2094,18684,0.00527342709135581,0.0184667604254701,1.86296797758116,"PTGS1;EIF6;BAX;PLAU;MMP9;CAT;CTNNB1;VCAM1;PRKCD;PRKCB;PECAM1;PLAT;MPO;SLC2A4;PON1;EIF2S1;TNFSF10;CDC42;BSG"]
["GO:0043231","intracellular membrane-bounded organelle","cellular_component",10,91,868,18684,0.00954028798050274,0.0296721785709386,2.36542259583734,"PTGS1;CAT;PPARG;CYP1A1;CYP1B1;MPO;PON1;IRS1;BSG;SPARC"]
["GO:0035578","azurophil granule lumen","cellular_component",3,91,91,18684,0.00997181916838333,0.0305619287640403,6.7687477357807,"MAPK1;PRKCD;MPO"]
["GO:0005769","early endosome","cellular_component",5,91,269,18684,0.0101498957025302,0.0310573669473861,3.81633236651824,"MAPK3;MAPK1;VCAM1;PTPN1;NTRK1"]
["GO:0005635","nuclear envelope","cellular_component",4,91,178,18684,0.0111947020588923,0.033763563020429,4.6139029509816,"BAX;MAPK3;SREBF1;MTOR"]
["GO:0042383","sarcolemma","cellular_component",3,91,97,18684,0.0118526439062006,0.0351464896317704,6.3500623088252,"VCAM1;SLC2A4;BSG"]
["GO:0009897","external side of plasma membrane","cellular_component",5,91,283,18684,0.0124328982254218,0.036678019569848,3.62753853919932,"VCAM1;SLC2A4;CD80;CCR2;CD28"]
["GO:0005813","centrosome","cellular_component",7,91,520,18684,0.0134911713252173,0.0392489307322862,2.76390532544379,"BCL2L1;CTNNB1;CCNB1;NFE2L2;CCNE1;CDC42;BRCA2"]
["GO:0031226","intrinsic component of plasma membrane","cellular_component",2,91,37,18684,0.0139890121743472,0.0403865985063978,11.0983070983071,"ADIPOR1;ADIPOR2"]
["GO:0030424","axon","cellular_component",5,91,301,18684,0.0158506101361197,0.0451408189268108,3.41060932423059,"MAPK1;MAPK8;STAT1;NTRK1;BSG"]
["GO:0016363","nuclear matrix","cellular_component",3,91,109,18684,0.0161888118549765,0.0459443767744466,5.65097288033068,"RUNX1T1;PRKCD;SPARC"]
["GO:0016529","sarcoplasmic reticulum","cellular_component",2,91,43,18684,0.0186133666093988,0.0514588834186742,9.54970610784564,"XDH;SLC2A4"]
["GO:0043025","neuronal cell body","cellular_component",5,91,328,18684,0.0220725719955367,0.0583979561038176,3.12985794693112,"CASP3;NTRK1;MTOR;CCR2;CDC42"]
["GO:0071944","cell periphery","cellular_component",2,91,49,18684,0.0237896112871107,0.0583979561038176,8.38035433953801,"BAX;CTNNB1"]
["GO:0005850","eukaryotic translation initiation factor 2 complex","cellular_component",1,91,5,18684,0.0241188808657227,0.0583979561038176,41.0637362637363,"EIF2S1"]
["GO:0033093","Weibel-Palade body","cellular_component",1,91,5,18684,0.0241188808657227,0.0583979561038176,41.0637362637363,"EDN1"]
["GO:0097443","sorting endosome","cellular_component",1,91,5,18684,0.0241188808657227,0.0583979561038176,41.0637362637363,"PTPN1"]
["GO:0012505","endomembrane system","cellular_component",3,91,127,18684,0.0241576477906576,0.058417022982268,4.85004759020507,"SLC2A4;MTOR;BCL2L11"]
["GO:0016020","membrane","cellular_component",17,91,2109,18684,0.0249264583547837,0.0601991478274535,1.65501070764229,"VEGFA;BCL2;BAX;CAT;CTNNB1;XRCC6;HGF;CCNB1;SLC2A4;ADIPOR1;JAK1;MTOR;EIF2S1;PTGES;CDC42;BSG;CD320"]
["GO:0012507","ER to Golgi transport vesicle membrane","cellular_component",2,91,54,18684,0.0284994325288926,0.0632666810562526,7.60439560439561,"SREBF1;TGFA"]
["GO:0005851","eukaryotic translation initiation factor 2B complex","cellular_component",1,91,6,18684,0.0288731601012935,0.0632666810562526,34.2197802197802,"EIF2S1"]
["GO:0031265","CD95 death-inducing signaling complex","cellular_component",1,91,6,18684,0.0288731601012935,0.0632666810562526,34.2197802197802,"CFLAR"]
["GO:0032133","chromosome passenger complex","cellular_component",1,91,6,18684,0.0288731601012935,0.0632666810562526,34.2197802197802,"BIRC5"]
["GO:0097342","ripoptosome","cellular_component",1,91,6,18684,0.0288731601012935,0.0632666810562526,34.2197802197802,"CFLAR"]
["GO:0098802","plasma membrane signaling receptor complex","cellular_component",1,91,6,18684,0.0288731601012935,0.0632666810562526,34.2197802197802,"TRAF2"]
["GO:0000139","Golgi membrane","cellular_component",7,91,622,18684,0.0320695182212099,0.0673872405042206,2.31066040069256,"NOS3;NTRK1;SREBF1;MTOR;CDC42;BSG;TGFA"]
["GO:0005905","clathrin-coated pit","cellular_component",2,91,59,18684,0.033548730932523,0.0673872405042206,6.95995529893835,"SELE;SLC2A4"]
["GO:0097441","basal dendrite","cellular_component",1,91,7,18684,0.0336045308278583,0.0673872405042206,29.331240188383,"MAPK8"]
["GO:0001750","photoreceptor outer segment","cellular_component",2,91,63,18684,0.0378199804032399,0.0720896281374512,6.51805337519623,"PTGS1;BSG"]
["GO:0045335","phagocytic vesicle","cellular_component",2,91,63,18684,0.0378199804032399,0.0720896281374512,6.51805337519623,"MTOR;CDC42"]
["GO:0008274","gamma-tubulin ring complex","cellular_component",1,91,8,18684,0.0383131022094862,0.0720896281374512,25.6648351648352,"BRCA1"]
["GO:0030061","mitochondrial crista","cellular_component",1,91,8,18684,0.0383131022094862,0.0720896281374512,25.6648351648352,"PTPN1"]
["GO:0031931","TORC1 complex","cellular_component",1,91,8,18684,0.0383131022094862,0.0720896281374512,25.6648351648352,"MTOR"]
["GO:0034366","spherical high-density lipoprotein particle","cellular_component",1,91,8,18684,0.0383131022094862,0.0720896281374512,25.6648351648352,"PON1"]
["GO:0034751","aryl hydrocarbon receptor complex","cellular_component",1,91,8,18684,0.0383131022094862,0.0720896281374512,25.6648351648352,"AHR"]
["GO:0070419","nonhomologous end joining complex","cellular_component",1,91,8,18684,0.0383131022094862,0.0720896281374512,25.6648351648352,"XRCC6"]
["GO:0070531","BRCA1-A complex","cellular_component",1,91,8,18684,0.0383131022094862,0.0720896281374512,25.6648351648352,"BRCA1"]
["GO:0045177","apical part of cell","cellular_component",2,91,64,18684,0.0389187721482793,0.0730113076710279,6.41620879120879,"VCAM1;CDC42"]
["GO:0005764","lysosome","cellular_component",4,91,269,18684,0.0424632391809136,0.0764920758759111,3.05306589321459,"CAT;IL1B;MPO;MTOR"]
["GO:0000783","nuclear telomere cap complex","cellular_component",1,91,9,18684,0.0429989828958718,0.0764920758759111,22.8131868131868,"XRCC6"]
["GO:0008091","spectrin","cellular_component",1,91,9,18684,0.0429989828958718,0.0764920758759111,22.8131868131868,"PRKCB"]
["GO:0031256","leading edge membrane","cellular_component",1,91,9,18684,0.0429989828958718,0.0764920758759111,22.8131868131868,"CDC42"]
["GO:0031588","nucleotide-activated protein kinase complex","cellular_component",1,91,9,18684,0.0429989828958718,0.0764920758759111,22.8131868131868,"PRKAG2"]
["GO:0030175","filopodium","cellular_component",2,91,70,18684,0.0457608413971314,0.0804008683476973,5.86624803767661,"VCAM1;CDC42"]
["GO:0005641","nuclear envelope lumen","cellular_component",1,91,10,18684,0.0476622810247322,0.0804008683476973,20.5318681318681,"PTGES"]
["GO:0032593","insulin-responsive compartment","cellular_component",1,91,10,18684,0.0476622810247322,0.0804008683476973,20.5318681318681,"SLC2A4"]
["GO:0035631","CD40 receptor complex","cellular_component",1,91,11,18684,0.052303104224194,0.0854103368635155,18.6653346653347,"TRAF2"]
["GO:0042582","azurophil granule","cellular_component",1,91,11,18684,0.052303104224194,0.0854103368635155,18.6653346653347,"MPO"]
["GO:0099523","presynaptic cytosol","cellular_component",1,91,11,18684,0.052303104224194,0.0854103368635155,18.6653346653347,"PRKCB"]
["GO:0030877","beta-catenin destruction complex","cellular_component",1,91,12,18684,0.0569215596151652,0.0897737024456025,17.1098901098901,"CTNNB1"]
["GO:0031932","TORC2 complex","cellular_component",1,91,12,18684,0.0569215596151652,0.0897737024456025,17.1098901098901,"MTOR"]
["GO:1990909","Wnt signalosome","cellular_component",1,91,12,18684,0.0569215596151652,0.0897737024456025,17.1098901098901,"CTNNB1"]
["GO:0017119","Golgi transport complex","cellular_component",1,91,13,18684,0.0615177538136986,0.09450046503794,15.7937447168216,"CDC42"]
["GO:1990907","beta-catenin-TCF complex","cellular_component",1,91,13,18684,0.0615177538136986,0.09450046503794,15.7937447168216,"CTNNB1"]
["GO:0031091","platelet alpha granule","cellular_component",1,91,15,18684,0.0706437825875019,0.10347590462662,13.6879120879121,"SPARC"]
["GO:0033290","eukaryotic 48S preinitiation complex","cellular_component",1,91,15,18684,0.0706437825875019,0.10347590462662,13.6879120879121,"EIF2S1"]
["GO:0045178","basal part of cell","cellular_component",1,91,15,18684,0.0706437825875019,0.10347590462662,13.6879120879121,"EDN1"]
["GO:0005887","integral component of plasma membrane","cellular_component",11,91,1392,18684,0.0751358957402802,0.107692203441857,1.62248957938613,"SELE;VCAM1;PECAM1;SLC2A4;NTRK1;AGTR1;CCR2;TNFSF10;BSG;CD28;CD320"]
["GO:0044305","calyx of Held","cellular_component",1,91,16,18684,0.0751738278917243,0.107692203441857,12.8324175824176,"PRKCB"]
["GO:0071682","endocytic vesicle lumen","cellular_component",1,91,16,18684,0.0751738278917243,0.107692203441857,12.8324175824176,"SPARC"]
["GO:0099524","postsynaptic cytosol","cellular_component",1,91,16,18684,0.0751738278917243,0.107692203441857,12.8324175824176,"MTOR"]
["GO:0030140","trans-Golgi network transport vesicle","cellular_component",1,91,17,18684,0.0796820334660687,0.112028792032964,12.0775694893342,"SLC2A4"]
["GO:0043235","receptor complex","cellular_component",3,91,209,18684,0.0821373090029937,0.115309317984158,2.94715810505284,"PPARG;NTRK1;NR1H3"]
["GO:0030863","cortical cytoskeleton","cellular_component",1,91,18,18684,0.0841685034373864,0.116346959064399,11.4065934065934,"SELE"]
["GO:0016323","basolateral plasma membrane","cellular_component",3,91,212,18684,0.0848780351371499,0.117242048534953,2.90545303752851,"CTNNB1;BSG;TGFA"]
["GO:0002080","acrosomal membrane","cellular_component",1,91,20,18684,0.0930766506261355,0.125809825828465,10.2659340659341,"BSG"]
["GO:0000151","ubiquitin ligase complex","cellular_component",2,91,106,18684,0.0943825451417215,0.127392857147034,3.87393738337135,"BRCA1;TRAF2"]
["GO:0005777","peroxisome","cellular_component",2,91,108,18684,0.0973978510580251,0.129655223020927,3.8021978021978,"XDH;CAT"]
["GO:0030687","preribosome, large subunit precursor","cellular_component",1,91,22,18684,0.101899092695881,0.133720460990917,9.33266733266733,"EIF6"]
["GO:0031965","nuclear membrane","cellular_component",3,91,233,18684,0.105120855695028,0.137566462366296,2.64358817148517,"CCND1;BCL2;BCL2L1"]
["GO:0034364","high-density lipoprotein particle","cellular_component",1,91,23,18684,0.106278429453178,0.137652404175315,8.92689918776875,"PON1"]
["GO:0072686","mitotic spindle","cellular_component",2,91,114,18684,0.106604145294106,0.137979766427895,3.60208212839792,"MAPK1;CDC42"]
["GO:0034774","secretory granule lumen","cellular_component",2,91,115,18684,0.108160880527807,0.139803298071143,3.5707596751075,"CAT;XRCC6"]
["GO:0005794","Golgi apparatus","cellular_component",8,91,990,18684,0.109124306243388,0.140952228897709,1.65914085914086,"PTGS1;MAPK3;MAPK1;CAT;VCAM1;NOS3;NFE2L2;TNFRSF10A"]
["GO:0062023","collagen-containing extracellular matrix","cellular_component",4,91,375,18684,0.110558329275658,0.141743831950219,2.19006593406593,"MMP2;MMP9;PLAT;SPARC"]
["GO:0051233","spindle midzone","cellular_component",1,91,25,18684,0.114973840492642,0.146506423430988,8.21274725274725,"CDC42"]
["GO:0000922","spindle pole","cellular_component",2,91,120,18684,0.116034601586386,0.147758539797883,3.42197802197802,"CTNNB1;CCNB1"]
["GO:0005640","nuclear outer membrane","cellular_component",1,91,26,18684,0.119290115776161,0.15058585376016,7.89687235841082,"PTGS2"]
["GO:0002102","podosome","cellular_component",1,91,27,18684,0.123585570780147,0.154461542858729,7.60439560439561,"VCAM1"]
["GO:0043209","myelin sheath","cellular_component",1,91,28,18684,0.127860304824152,0.158028651256517,7.33281004709576,"BCL2"]
["GO:0005783","endoplasmic reticulum","cellular_component",8,91,1032,18684,0.129630714128643,0.160112136131459,1.59161768464094,"PTGS2;BCL2;BAX;CAT;VCAM1;PRKCD;PTPN1;CD320"]
["GO:0030425","dendrite","cellular_component",4,91,402,18684,0.132889185809288,0.162544275786135,2.04297195341971,"STAT1;NTRK1;MTOR;CCR2"]
["GO:0005856","cytoskeleton","cellular_component",4,91,403,18684,0.133750177985884,0.163491652599423,2.03790254410602,"MAPK3;MAPK1;NOS3;JAK1"]
["GO:0016342","catenin complex","cellular_component",1,91,31,18684,0.140561167377574,0.16940800988591,6.62318326834456,"CTNNB1"]
["GO:0032839","dendrite cytoplasm","cellular_component",1,91,31,18684,0.140561167377574,0.16940800988591,6.62318326834456,"MAPK1"]
["GO:0005938","cell cortex","cellular_component",2,91,145,18684,0.157309266099457,0.186385853505059,2.83198181129216,"CTNNB1;TRAF2"]
["GO:0000791","euchromatin","cellular_component",1,91,36,18684,0.161323987366686,0.190545696508684,5.7032967032967,"CTNNB1"]
["GO:0043204","perikaryon","cellular_component",2,91,151,18684,0.16759571690856,0.19709172927493,2.71945273269777,"MAPK1;CCR2"]
["GO:0005844","polysome","cellular_component",1,91,39,18684,0.17354273672836,0.202698774029233,5.26458157227388,"EIF2S1"]
["GO:0000781","chromosome, telomeric region","cellular_component",2,91,159,18684,0.181485260406006,0.210280343225174,2.58262492224756,"XRCC6;BRCA2"]
["GO:0001772","immunological synapse","cellular_component",1,91,41,18684,0.181590587248392,0.210280343225174,5.00777271508979,"CD28"]
["GO:0005771","multivesicular body","cellular_component",1,91,41,18684,0.181590587248392,0.210280343225174,5.00777271508979,"SLC2A4"]
["GO:0098978","glutamatergic synapse","cellular_component",3,91,303,18684,0.183682997557999,0.212573163024587,2.03285823087803,"RELA;MTOR;SPARC"]
["GO:0005876","spindle microtubule","cellular_component",1,91,42,18684,0.185585397984883,0.213989016822814,4.88854003139718,"BIRC5"]
["GO:0030315","T-tubule","cellular_component",1,91,42,18684,0.185585397984883,0.213989016822814,4.88854003139718,"SLC2A4"]
["GO:0005912","adherens junction","cellular_component",2,91,163,18684,0.188494823803227,0.21721128081164,2.5192476235421,"VEGFA;CTNNB1"]
["GO:0030017","sarcomere","cellular_component",1,91,44,18684,0.193517252998431,0.220712379626075,4.66633366633367,"MMP2"]
["GO:0030496","midbody","cellular_component",2,91,168,18684,0.197309179383188,0.224660904677395,2.44427001569859,"BIRC5;CDC42"]
["GO:0016604","nuclear body","cellular_component",3,91,321,18684,0.20596740480057,0.233503814435178,1.91886618054842,"NCOA2;CDKN1A;BRCA1"]
["GO:0005637","nuclear inner membrane","cellular_component",1,91,48,18684,0.209152460265458,0.236547429642333,4.27747252747253,"PTGS2"]
["GO:0005782","peroxisomal matrix","cellular_component",1,91,51,18684,0.220681775379125,0.247661268392834,4.02585649644473,"CAT"]
["GO:0000228","nuclear chromosome","cellular_component",1,91,52,18684,0.224487816190615,0.251038711068275,3.94843617920541,"BIRC5"]
["GO:0017053","transcription repressor complex","cellular_component",1,91,52,18684,0.224487816190615,0.251038711068275,3.94843617920541,"CCND1"]
["GO:0009898","cytoplasmic side of plasma membrane","cellular_component",1,91,53,18684,0.228275472305184,0.254371784401358,3.87393738337135,"TRAF2"]
["GO:0005730","nucleolus","cellular_component",6,91,847,18684,0.231046120130232,0.257307546034316,1.45444166223387,"RELA;CDKN1A;EIF6;STAT1;MYC;XRCC6"]
["GO:1904724","tertiary granule lumen","cellular_component",1,91,55,18684,0.235795981322376,0.261519179284817,3.73306693306693,"MMP9"]
["GO:0000775","chromosome, centromeric region","cellular_component",1,91,56,18684,0.239529008629245,0.264573221564195,3.66640502354788,"BIRC5"]
["GO:0030665","clathrin-coated vesicle membrane","cellular_component",1,91,56,18684,0.239529008629245,0.264573221564195,3.66640502354788,"TGFA"]
["GO:0005778","peroxisomal membrane","cellular_component",1,91,58,18684,0.246941041764942,0.271807630953146,3.5399772641152,"CAT"]
["GO:0001917","photoreceptor inner segment","cellular_component",1,91,59,18684,0.250620219537915,0.275216512860742,3.47997764946917,"BSG"]
["GO:0030136","clathrin-coated vesicle","cellular_component",1,91,61,18684,0.257925324312297,0.281603226486463,3.36588002161773,"SLC2A4"]
["GO:0016328","lateral plasma membrane","cellular_component",1,91,62,18684,0.261551420832061,0.285397424577858,3.31159163417228,"CTNNB1"]
["GO:0005759","mitochondrial matrix","cellular_component",3,91,373,18684,0.27320831822251,0.297259453255907,1.65135668620923,"BCL2L1;PTPN1;CCNB1"]
["GO:0031234","extrinsic component of cytoplasmic side of plasma membrane","cellular_component",1,91,66,18684,0.275881393545551,0.299478596552605,3.11088911088911,"AKT1"]
["GO:0019898","extrinsic component of membrane","cellular_component",1,91,67,18684,0.279420699227544,0.302972787981242,3.06445793012957,"BCL2L11"]
["GO:0098685","Schaffer collateral - CA1 synapse","cellular_component",1,91,67,18684,0.279420699227544,0.302972787981242,3.06445793012957,"CDC42"]
["GO:0005902","microvillus","cellular_component",1,91,68,18684,0.282942894875087,0.306265033891694,3.01939237233355,"VCAM1"]
["GO:0030666","endocytic vesicle membrane","cellular_component",1,91,68,18684,0.282942894875087,0.306265033891694,3.01939237233355,"NOS3"]
["GO:0030672","synaptic vesicle membrane","cellular_component",1,91,71,18684,0.293407637681605,0.315425720782214,2.89181241293917,"BCL2L1"]
["GO:0033116","endoplasmic reticulum-Golgi intermediate compartment membrane","cellular_component",1,91,72,18684,0.296862207335662,0.318777077837443,2.85164835164835,"TGFA"]
["GO:0045202","synapse","cellular_component",3,91,392,18684,0.29842430035305,0.320272617461758,1.57131643866338,"MAPK8;CTNNB1;EIF2S1"]
["GO:0070821","tertiary granule membrane","cellular_component",1,91,73,18684,0.300300072107447,0.321920315394094,2.81258467559837,"PLAU"]
["GO:0010008","endosome membrane","cellular_component",2,91,226,18684,0.301537388048452,0.323063569858143,1.81697948069629,"NTRK1;CD320"]
["GO:0010494","cytoplasmic stress granule","cellular_component",1,91,74,18684,0.303721311881678,0.325035088154077,2.77457677457677,"EIF2S1"]
["GO:0005758","mitochondrial intermembrane space","cellular_component",1,91,81,18684,0.327211121802927,0.34761586029738,2.53479853479854,"CAT"]
["GO:0036464","cytoplasmic ribonucleoprotein granule","cellular_component",1,91,81,18684,0.327211121802927,0.34761586029738,2.53479853479854,"CDC42"]
["GO:0005604","basement membrane","cellular_component",1,91,83,18684,0.333777340345505,0.353598291648936,2.47371905203231,"SPARC"]
["GO:0055038","recycling endosome membrane","cellular_component",1,91,84,18684,0.337036641567405,0.356641225982085,2.44427001569859,"NTRK1"]
["GO:0000777","condensed chromosome kinetochore","cellular_component",1,91,86,18684,0.343508007040659,0.362890302409992,2.38742652696141,"BIRC5"]
["GO:0098794","postsynapse","cellular_component",1,91,89,18684,0.353098089476125,0.371982444122201,2.3069514754908,"AKT1"]
["GO:0035579","specific granule membrane","cellular_component",1,91,91,18684,0.359414368598543,0.37800476697433,2.25624924526023,"PLAU"]
["GO:0030133","transport vesicle","cellular_component",1,91,92,18684,0.362549596504612,0.381090209555432,2.23172479694219,"EDN1"]
["GO:0005815","microtubule organizing center","cellular_component",1,91,97,18684,0.377999529229703,0.395790204747158,2.11668743627507,"MAPK1"]
["GO:0030667","secretory granule membrane","cellular_component",1,91,97,18684,0.377999529229703,0.395790204747158,2.11668743627507,"PECAM1"]
["GO:0042470","melanosome","cellular_component",1,91,99,18684,0.384075281019964,0.40148499525083,2.07392607392607,"BSG"]
["GO:0016605","PML body","cellular_component",1,91,103,18684,0.396051237826198,0.412862674051455,1.99338525552118,"MTOR"]
["GO:0098793","presynapse","cellular_component",1,91,106,18684,0.404881797632052,0.421835525797361,1.93696869168567,"SLC2A4"]
["GO:0005768","endosome","cellular_component",2,91,289,18684,0.41220253167086,0.428990086620581,1.42089052815696,"JAK1;BSG"]
["GO:0072562","blood microparticle","cellular_component",1,91,112,18684,0.422161594375246,0.438389662253482,1.83320251177394,"PON1"]
["GO:0005788","endoplasmic reticulum lumen","cellular_component",2,91,299,18684,0.429050543487628,0.445054623003349,1.37336910581058,"PTGS2;IL6"]
["GO:0005923","bicellular tight junction","cellular_component",1,91,117,18684,0.436181642446146,0.451955882666116,1.75486052409129,"CCND1"]
["GO:0031902","late endosome membrane","cellular_component",1,91,121,18684,0.447155000892289,0.462818887075708,1.69684860593952,"NTRK1"]
["GO:0042995","cell projection","cellular_component",1,91,121,18684,0.447155000892289,0.462818887075708,1.69684860593952,"CTNNB1"]
["GO:0005819","spindle","cellular_component",1,91,125,18684,0.457917091166856,0.472922566573744,1.64254945054945,"AKT1"]
["GO:0043005","neuron projection","cellular_component",2,91,318,18684,0.460357913369431,0.475148646558901,1.29131246112378,"PTGS2;CDC42"]
["GO:0030659","cytoplasmic vesicle membrane","cellular_component",1,91,143,18684,0.503838164082507,0.515282838442413,1.43579497425651,"SLC2A4"]
["GO:0043197","dendritic spine","cellular_component",1,91,150,18684,0.52063817478198,0.530456243810735,1.36879120879121,"CDC42"]
["GO:1990904","ribonucleoprotein complex","cellular_component",1,91,151,18684,0.522991791167803,0.532567300537596,1.35972636634888,"BRCA1"]
["GO:0036064","ciliary basal body","cellular_component",1,91,153,18684,0.527664789917351,0.537036661858833,1.34195216548158,"AKT1"]
["GO:0031901","early endosome membrane","cellular_component",1,91,157,18684,0.536875379175003,0.545823302161253,1.30776230139287,"NTRK1"]
["GO:0031982","vesicle","cellular_component",1,91,157,18684,0.536875379175003,0.545823302161253,1.30776230139287,"AKT1"]
["GO:0015630","microtubule cytoskeleton","cellular_component",1,91,165,18684,0.554766931802875,0.563709977452572,1.24435564435564,"AKT1"]
["GO:0005743","mitochondrial inner membrane","cellular_component",2,91,382,18684,0.558101096773332,0.566793326529738,1.07496691789886,"BCL2L1;CYP1A1"]
["GO:0005802","trans-Golgi network","cellular_component",1,91,177,18684,0.580330092657929,0.588420485370587,1.15999254982306,"SLC2A4"]
["GO:0030027","lamellipodium","cellular_component",1,91,179,18684,0.584447139957351,0.59196011872488,1.14703173921051,"AKT1"]
["GO:0005694","chromosome","cellular_component",1,91,190,18684,0.606386996448079,0.613196689991079,1.08062463851938,"BRCA1"]
["GO:0030054","cell junction","cellular_component",1,91,195,18684,0.615977084665241,0.622561553769092,1.05291631445478,"CTNNB1"]
["GO:0014069","postsynaptic density","cellular_component",1,91,236,18684,0.686377938174759,0.69223502991385,0.869994412367294,"MAPK1"]
["GO:0031012","extracellular matrix","cellular_component",1,91,244,18684,0.698544868611052,0.703755112702983,0.841470005404432,"VEGFA"]
["GO:0031410","cytoplasmic vesicle","cellular_component",1,91,283,18684,0.751489992023642,0.756691999423167,0.725507707839863,"TGFA"]
["GO:0005765","lysosomal membrane","cellular_component",1,91,318,18684,0.791110713448124,0.794893920898194,0.645656230561891,"MTOR"]
["GO:0005575","cellular_component","cellular_component",1,91,393,18684,0.85618673345219,0.858456581632074,0.5224393926684,"ODC1"]
["GO:0016607","nuclear speck","cellular_component",1,91,410,18684,0.86788268298938,0.869722391909336,0.500777271508979,"AAGAB"]
["GO:0016021","integral component of membrane","cellular_component",10,91,3533,18684,0.985642734867454,0.985642734867454,0.581145432546508,"BCL2L1;CD80;SREBF1;ADIPOR1;ADIPOR2;AGTR1;CCR2;PTGES;TNFRSF10A;TGFA"]
["GO:0019901","protein kinase binding","molecular_function",18,91,453,18684,{"v":5.56141853902389e-12,"d":"5.56E-12"},{"v":1.31458030716177e-09,"d":"1.31E-09"},8.1583581980933,"RELA;STAT3;CCND1;BCL2L1;CDKN1A;CASP9;PRKCD;PTPN1;CCNB1;PRKAG2;CCNE1;SREBF1;ADIPOR1;MTOR;BCL2L11;TRAF2;CDC42;CD28"]
["GO:0005515","protein binding","molecular_function",87,91,12317,18684,{"v":6.52067221661944e-12,"d":"6.52E-12"},{"v":1.37006568462526e-09,"d":"1.37E-09"},1.45024967725301,"PTGS1;PTGS2;NCOA2;RELA;STAT3;AKT1;VEGFA;CCND1;BCL2;BCL2L1;CDKN1A;EIF6;BAX;CASP9;PLAU;MMP2;MMP9;MAPK3;MAPK1;IL10;IL6;CASP3;MAPK8;NFKBIA;ODC1;XDH;STAT1;RUNX1T1;EDN1;FOXO1;PPARG;CTNNB1;MYC;CYP1A1;IL1B;SELE;PRKCD;CXCL8;BRCA1;XRCC6;PRKCB;PECAM1;BIRC5;NOS3;PTPN1;BCL2A1;HGF;CCNB1;DDIT3;PLAT;IL1A;MPO;NFE2L2;AHR;PRKAG2;SLC2A4;PPARA;CRP;CD80;CCNE1;NTRK1;KLF10;SREBF1;ADIPOR1;ADIPOR2;JAK1;AGTR1;IRS1;CFLAR;MTOR;CCR2;EIF2S1;PTGES;BCL2L11;TNFSF10;TNFRSF10A;TRAF2;CDC42;BSG;CD28;NR1H3;PAPPA;SPARC;BRCA2;AAGAB;TGFA;CD320"]
["GO:0019899","enzyme binding","molecular_function",16,91,360,18684,{"v":1.81718709644793e-11,"d":"1.82E-11"},{"v":2.86358399948587e-09,"d":"2.86E-09"},9.12527472527473,"PTGS2;RELA;AKT1;CCND1;MAPK8;NFKBIA;CAT;STAT1;PPARG;CTNNB1;CYP1A1;PRKCD;BRCA1;BIRC5;PTPN1;TRAF2"]
["GO:0042802","identical protein binding","molecular_function",28,91,1459,18684,{"v":1.36774360868662e-10,"d":"1.37E-10"},{"v":1.6165019775165e-08,"d":"1.62E-08"},3.94031739336743,"RELA;STAT3;AKT1;VEGFA;BCL2;BCL2L1;BAX;MMP9;MAPK3;MAPK1;NFKBIA;CAT;STAT1;PPARG;BRCA1;BIRC5;HGF;CRP;NTRK1;ADIPOR1;MTOR;CCR2;TNFSF10;TNFRSF10A;TRAF2;CDC42;CD28;BRCA2"]
["GO:0008134","transcription factor binding","molecular_function",12,91,285,18684,{"v":1.36001587499835e-08,"d":"1.36E-08"},{"v":8.29609683748994e-07,"d":"8.30E-07"},8.644997108155,"RELA;STAT3;CCND1;MAPK1;NFKBIA;PPARG;CTNNB1;MYC;DDIT3;AHR;PPARA;TNFRSF10A"]
["GO:0042803","protein homodimerization activity","molecular_function",17,91,666,18684,{"v":1.93967835370006e-08,"d":"1.94E-08"},{"v":1.0567573367203e-06,"d":"1.06E-06"},5.24086724086724,"RELA;STAT3;AKT1;VEGFA;BCL2;BCL2L1;BAX;ODC1;XDH;CAT;STAT1;PECAM1;BCL2A1;DDIT3;AHR;PON1;NTRK1"]
["GO:0044877","protein-containing complex binding","molecular_function",12,91,340,18684,{"v":9.45550345536848e-08,"d":"9.46E-08"},{"v":4.15586701307098e-06,"d":"4.16E-06"},7.24654169360052,"RELA;CCND1;CDKN1A;CASP3;MYC;XRCC6;BCL2A1;HGF;PPARA;SREBF1;CFLAR;TRAF2"]
["GO:0004879","nuclear receptor activity","molecular_function",6,91,52,18684,{"v":1.92058941322992e-07,"d":"1.92E-07"},{"v":7.26366916083557e-06,"d":"7.26E-06"},23.6906170752325,"STAT3;PPARG;AHR;PPARA;SREBF1;NR1H3"]
["GO:0000976","transcription regulatory region sequence-specific DNA binding","molecular_function",9,91,203,18684,{"v":6.41681789238816e-07,"d":"6.42E-07"},{"v":1.98921354664033e-05,"d":"1.99E-05"},9.10279867915336,"RELA;STAT3;PPARG;BRCA1;XRCC6;DDIT3;NFE2L2;AHR;NR1H3"]
["GO:0003700","DNA-binding transcription factor activity","molecular_function",12,91,447,18684,{"v":1.73276681631475e-06,"d":"1.73E-06"},{"v":4.20084878160409e-05,"d":"4.20E-05"},5.51191090788406,"RELA;STAT3;STAT1;FOXO1;PPARG;MYC;DDIT3;NFE2L2;AHR;PPARA;KLF10;SREBF1"]
["GO:0051434","BH3 domain binding","molecular_function",3,91,6,18684,{"v":2.21184005652551e-06,"d":"2.21E-06"},{"v":5.1636907986293e-05,"d":"5.16E-05"},102.659340659341,"BCL2;BCL2L1;BAX"]
["GO:0020037","heme binding","molecular_function",7,91,136,18684,{"v":4.51149143645758e-06,"d":"4.51E-06"},{"v":8.88669823577217e-05,"d":"8.89E-05"},10.5678733031674,"PTGS1;PTGS2;CAT;CYP1A1;NOS3;CYP1B1;MPO"]
["GO:0002020","protease binding","molecular_function",6,91,99,18684,{"v":8.80120677638042e-06,"d":"8.80E-06"},0.000147300721846419,12.4435564435564,"BCL2;CASP3;CFLAR;TNFRSF10A;CD28;BRCA2"]
["GO:0097199","cysteine-type endopeptidase activity involved in apoptotic signaling pathway","molecular_function",3,91,9,18684,{"v":9.19168967629688e-06,"d":"9.19E-06"},0.000147300721846419,68.4395604395604,"CASP9;CASP3;CFLAR"]
["GO:0051721","protein phosphatase 2A binding","molecular_function",4,91,31,18684,{"v":1.49808720305208e-05,"d":"1.50E-05"},0.000221318976638396,26.4927330733782,"AKT1;BCL2;FOXO1;PTPN1"]
["GO:0097200","cysteine-type endopeptidase activity involved in execution phase of apoptosis","molecular_function",3,91,12,18684,{"v":2.38195631122793e-05,"d":"2.38E-05"},0.000317202773558593,51.3296703296703,"CASP9;CASP3;CFLAR"]
["GO:0097153","cysteine-type endopeptidase activity involved in apoptotic process","molecular_function",3,91,13,18684,{"v":3.08562226600437e-05,"d":"3.09E-05"},0.000391604812417065,47.3812341504649,"CASP9;CASP3;CFLAR"]
["GO:0005125","cytokine activity","molecular_function",7,91,187,18684,{"v":3.58241076916768e-05,"d":"3.58E-05"},0.000445680181874742,7.68572603866722,"VEGFA;IL10;IL6;EDN1;IL1B;IL1A;TNFSF10"]
["GO:0070491","repressing transcription factor binding","molecular_function",4,91,40,18684,{"v":4.20793527765039e-05,"d":"4.21E-05"},0.000497325350627305,20.5318681318681,"RELA;BCL2;STAT1;MYC"]
["GO:0019903","protein phosphatase binding","molecular_function",5,91,86,18684,{"v":6.26039200445367e-05,"d":"6.26E-05"},0.000684300652047508,11.9371326348071,"STAT3;PPARG;CTNNB1;JAK1;TRAF2"]
["GO:0016301","kinase activity","molecular_function",5,91,87,18684,{"v":6.61678059427019e-05,"d":"6.62E-05"},0.000714990405929425,11.7999242137173,"AKT1;MAPK1;MAPK8;CCNE1;MTOR"]
["GO:0031625","ubiquitin protein ligase binding","molecular_function",8,91,290,18684,{"v":8.52567071620025e-05,"d":"8.53E-05"},0.000866776522813692,5.66396362258431,"RELA;BCL2;CDKN1A;NFKBIA;FOXO1;BRCA1;JAK1;TRAF2"]
["GO:0031435","mitogen-activated protein kinase kinase kinase binding","molecular_function",3,91,18,18684,{"v":8.64966906515086e-05,"d":"8.65E-05"},0.000870027883095759,34.2197802197802,"MAPK1;TRAF2;CDC42"]
["GO:0001223","transcription coactivator binding","molecular_function",3,91,20,18684,0.000119991186071789,0.00114021775307413,30.7978021978022,"FOXO1;AHR;PPARA"]
["GO:0004707","MAP kinase activity","molecular_function",3,91,20,18684,0.000119991186071789,0.00114021775307413,30.7978021978022,"MAPK3;MAPK1;MAPK8"]
["GO:0008083","growth factor activity","molecular_function",6,91,161,18684,0.00013585974846486,0.00128455392173525,7.65162787523036,"VEGFA;IL10;IL6;HGF;TGFA;CD320"]
["GO:0045569","TRAIL binding","molecular_function",2,91,5,18684,0.000232393738599392,0.0018621040664892,82.1274725274725,"TNFSF10;TNFRSF10A"]
["GO:0035257","nuclear hormone receptor binding","molecular_function",3,91,25,18684,0.000237856793030193,0.00187411331508373,24.6382417582418,"NCOA2;STAT1;CTNNB1"]
["GO:0001228","DNA-binding transcription activator activity, RNA polymerase II-specific","molecular_function",9,91,441,18684,0.000296861557861295,0.0022727336271891,4.19017716976901,"RELA;STAT3;FOXO1;MYC;DDIT3;NFE2L2;PPARA;KLF10;SREBF1"]
["GO:0003677","DNA binding","molecular_function",13,91,905,18684,0.000427402280779141,0.00293897350164856,2.94932912391476,"RELA;STAT3;RUNX1T1;PPARG;MYC;BRCA1;XRCC6;DDIT3;NFE2L2;AHR;PPARA;SREBF1;NR1H3"]
["GO:0005164","tumor necrosis factor receptor binding","molecular_function",3,91,31,18684,0.00045513410821705,0.00304119646161993,19.8695498050337,"STAT1;TNFSF10;TRAF2"]
["GO:0016538","cyclin-dependent protein serine/threonine kinase regulator activity","molecular_function",3,91,31,18684,0.00045513410821705,0.00304119646161993,19.8695498050337,"CCND1;CCNB1;CCNE1"]
["GO:0033613","activating transcription factor binding","molecular_function",3,91,31,18684,0.00045513410821705,0.00304119646161993,19.8695498050337,"RELA;PPARG;MYC"]
["GO:0106256","hydroperoxy icosatetraenoate dehydratase activity","molecular_function",2,91,7,18684,0.000484935741902735,0.00305671162646024,58.6624803767661,"CYP1A1;CYP1B1"]
["GO:0004601","peroxidase activity","molecular_function",3,91,33,18684,0.000548563821714142,0.00340109569462768,18.6653346653347,"PTGS1;PTGS2;MPO"]
["GO:0101020","estrogen 16-alpha-hydroxylase activity","molecular_function",2,91,8,18684,0.000644531156462674,0.00373867612537091,51.3296703296703,"CYP1A1;CYP1B1"]
["GO:0046983","protein dimerization activity","molecular_function",5,91,142,18684,0.00065052692461322,0.0037619156405003,7.22953103234793,"NCOA2;STAT3;IL10;MYC;SREBF1"]
["GO:0001103","RNA polymerase II repressing transcription factor binding","molecular_function",3,91,35,18684,0.000653441629053202,0.0037672503674988,17.5987441130298,"STAT3;PPARG;PPARA"]
["GO:0004674","protein serine/threonine kinase activity","molecular_function",7,91,310,18684,0.00079622915408622,0.00445185312079058,4.63622828784119,"AKT1;MAPK3;MAPK1;MAPK8;PRKCD;PRKCB;MTOR"]
["GO:0003682","chromatin binding","molecular_function",8,91,406,18684,0.000818685680369233,0.00445185312079058,4.04568830184594,"NCOA2;RELA;FOXO1;PPARG;CTNNB1;PRKCB;MPO;SREBF1"]
["GO:0004697","protein kinase C activity","molecular_function",2,91,9,18684,0.00082605671840164,0.00445185312079058,45.6263736263736,"PRKCD;PRKCB"]
["GO:0046982","protein heterodimerization activity","molecular_function",7,91,321,18684,0.000975816214735519,0.00514002357121133,4.47735442127966,"BCL2;BCL2L1;BAX;BCL2A1;DDIT3;AHR;AGTR1"]
["GO:0004252","serine-type endopeptidase activity","molecular_function",5,91,162,18684,0.00117548135577597,0.00594340974270685,6.33699633699634,"PLAU;MMP2;MMP9;HGF;PLAT"]
["GO:0031996","thioesterase binding","molecular_function",2,91,11,18684,0.00125404903011468,0.00615949796349834,37.3306693306693,"TRAF2;CDC42"]
["GO:0001784","phosphotyrosine residue binding","molecular_function",3,91,44,18684,0.00128109469740045,0.00625981930952002,13.999000999001,"MAPK3;MAPK1;IRS1"]
["GO:0003690","double-stranded DNA binding","molecular_function",4,91,99,18684,0.00139296947373398,0.00671965631334428,8.2957042957043,"MAPK1;STAT1;PPARG;XRCC6"]
["GO:0004861","cyclin-dependent protein serine/threonine kinase inhibitor activity","molecular_function",2,91,12,18684,0.00150009492351516,0.0069868953211014,34.2197802197802,"CDKN1A;CASP3"]
["GO:0070888","E-box binding","molecular_function",3,91,47,18684,0.00155205198901671,0.00717586873161516,13.1054477437456,"PPARG;MYC;AHR"]
["GO:0019902","phosphatase binding","molecular_function",3,91,48,18684,0.00164972427573964,0.00758943356782364,12.8324175824176,"MAPK3;MAPK1;PPARA"]
["GO:0015267","channel activity","molecular_function",2,91,13,18684,0.00176722923276154,0.00790030846135244,31.5874894336433,"BCL2;BAX"]
["GO:0008270","zinc ion binding","molecular_function",11,91,812,18684,0.00194081037211411,0.00863546450274773,2.78141070751908,"MMP2;MMP9;PPARG;BRCA1;PRKCB;PTPN1;PPARA;TNFSF10;TRAF2;NR1H3;PAPPA"]
["GO:0005149","interleukin-1 receptor binding","molecular_function",2,91,14,18684,0.00205524525827086,0.00885300406239223,29.331240188383,"IL1B;IL1A"]
["GO:0008047","enzyme activator activity","molecular_function",3,91,52,18684,0.00207857937071213,0.00889274567877066,11.8453085376162,"CASP9;PRKCD;CFLAR"]
["GO:0043022","ribosome binding","molecular_function",3,91,53,18684,0.00219558587572469,0.00928826150110825,11.621812150114,"EIF6;MTOR;EIF2S1"]
["GO:0005080","protein kinase C binding","molecular_function",3,91,54,18684,0.00231660654019782,0.00974850713431444,11.4065934065934,"AKT1;PRKCB;IRS1"]
["GO:0004698","calcium-dependent protein kinase C activity","molecular_function",2,91,16,18684,0.00269310302415808,0.0109266554738009,25.6648351648352,"PRKCD;PRKCB"]
["GO:0005123","death receptor binding","molecular_function",2,91,16,18684,0.00269310302415808,0.0109266554738009,25.6648351648352,"CASP3;CFLAR"]
["GO:0001046","core promoter sequence-specific DNA binding","molecular_function",2,91,17,18684,0.00304253870222112,0.0119614151474016,24.1551389786684,"MYC;KLF10"]
["GO:0000979","RNA polymerase II core promoter sequence-specific DNA binding","molecular_function",2,91,18,18684,0.00341204395366733,0.0129822436949395,22.8131868131868,"RELA;STAT1"]
["GO:0004708","MAP kinase kinase activity","molecular_function",2,91,18,18684,0.00341204395366733,0.0129822436949395,22.8131868131868,"MAPK3;MAPK1"]
["GO:0008237","metallopeptidase activity","molecular_function",3,91,63,18684,0.00359385081033534,0.0136191821289462,9.77708006279435,"MMP2;MMP9;PAPPA"]
["GO:0000978","RNA polymerase II cis-regulatory region sequence-specific DNA binding","molecular_function",13,91,1179,18684,0.00456647888547762,0.0165109207886007,2.2639040348964,"NCOA2;RELA;STAT3;STAT1;FOXO1;PPARG;MYC;DDIT3;NFE2L2;PPARA;KLF10;SREBF1;NR1H3"]
["GO:0005158","insulin receptor binding","molecular_function",2,91,22,18684,0.00508679372846588,0.0178794181050725,18.6653346653347,"PTPN1;IRS1"]
["GO:0044389","ubiquitin-like protein ligase binding","molecular_function",2,91,23,18684,0.00555368403534978,0.0191992989229368,17.8537983755375,"STAT1;CCNB1"]
["GO:0051213","dioxygenase activity","molecular_function",2,91,24,18684,0.00603946867109302,0.0206148650849042,17.1098901098901,"PTGS1;PTGS2"]
["GO:0070330","aromatase activity","molecular_function",2,91,24,18684,0.00603946867109302,0.0206148650849042,17.1098901098901,"CYP1A1;CYP1B1"]
["GO:0019904","protein domain specific binding","molecular_function",5,91,242,18684,0.00659392182333815,0.0219913689028791,4.24212151484879,"NCOA2;IL1B;NFE2L2;PPARA;MTOR"]
["GO:0043565","sequence-specific DNA binding","molecular_function",5,91,246,18684,0.00705479098145312,0.0231204469606484,4.17314392924149,"BCL2;FOXO1;PPARG;NFE2L2;PPARA"]
["GO:0000981","DNA-binding transcription factor activity, RNA polymerase II-specific","molecular_function",13,91,1245,18684,0.00715224027605706,0.0233590438031501,2.14388984509466,"RELA;STAT3;STAT1;FOXO1;PPARG;MYC;DDIT3;NFE2L2;AHR;PPARA;KLF10;SREBF1;NR1H3"]
["GO:0050840","extracellular matrix binding","molecular_function",2,91,28,18684,0.00816775159200376,0.0261340410498801,14.6656200941915,"VEGFA;SPARC"]
["GO:0008233","peptidase activity","molecular_function",3,91,87,18684,0.00882222768249442,0.0278047209126616,7.07995452823039,"CASP9;MMP9;CASP3"]
["GO:0030332","cyclin binding","molecular_function",2,91,30,18684,0.00934035864225428,0.0290982177800706,13.6879120879121,"CDKN1A;XRCC6"]
["GO:0051059","NF-kappaB binding","molecular_function",2,91,30,18684,0.00934035864225428,0.0290982177800706,13.6879120879121,"RELA;NFKBIA"]
["GO:0019900","kinase binding","molecular_function",3,91,97,18684,0.0118526439062006,0.0351464896317704,6.3500623088252,"CTNNB1;PRKCD;NTRK1"]
["GO:0019825","oxygen binding","molecular_function",2,91,34,18684,0.0118951630694516,0.0351464896317704,12.0775694893342,"CYP1A1;CYP1B1"]
["GO:0051219","phosphoprotein binding","molecular_function",2,91,34,18684,0.0118951630694516,0.0351464896317704,12.0775694893342,"PLAT;MTOR"]
["GO:0004497","monooxygenase activity","molecular_function",2,91,35,18684,0.0125764795203849,0.0368715081752679,11.7324960753532,"CYP1A1;CYP1B1"]
["GO:0042056","chemoattractant activity","molecular_function",2,91,35,18684,0.0125764795203849,0.0368715081752679,11.7324960753532,"VEGFA;HGF"]
["GO:0008022","protein C-terminus binding","molecular_function",4,91,185,18684,0.0127492661718518,0.0373202203265817,4.43932283932284,"PPARG;CTNNB1;XRCC6;BRCA2"]
["GO:0050661","NADP binding","molecular_function",2,91,38,18684,0.014719879617115,0.0422386833929658,10.8062463851938,"CAT;NOS3"]
["GO:0004222","metalloendopeptidase activity","molecular_function",3,91,107,18684,0.0154123132536382,0.0441145412256647,5.75659854164527,"MMP2;MMP9;PAPPA"]
["GO:0030544","Hsp70 protein binding","molecular_function",2,91,39,18684,0.0154669174154499,0.0441145412256647,10.5291631445478,"BAX;CYP1A1"]
["GO:0015026","coreceptor activity","molecular_function",2,91,40,18684,0.0162299543550134,0.0459443767744466,10.2659340659341,"CD80;CD28"]
["GO:0051879","Hsp90 protein binding","molecular_function",2,91,40,18684,0.0162299543550134,0.0459443767744466,10.2659340659341,"CYP1A1;AHR"]
["GO:0030331","estrogen receptor binding","molecular_function",2,91,41,18684,0.01700882047341,0.0479339486068826,10.0155454301796,"PPARG;CTNNB1"]
["GO:0042826","histone deacetylase binding","molecular_function",3,91,114,18684,0.0182250321035156,0.0508311736102478,5.40312319259688,"RELA;CCND1;MAPK8"]
["GO:0004715","non-membrane spanning protein tyrosine kinase activity","molecular_function",2,91,46,18684,0.0211347267067989,0.057754000292712,8.92689918776875,"PRKCD;JAK1"]
["GO:0004672","protein kinase activity","molecular_function",4,91,216,18684,0.0212646587073966,0.0580252086806451,3.8021978021978,"AKT1;CCND1;PRKCD;MTOR"]
["GO:0005506","iron ion binding","molecular_function",3,91,123,18684,0.0222337901720856,0.0583979561038176,5.00777271508979,"XDH;CYP1A1;CYP1B1"]
["GO:0001102","RNA polymerase II activating transcription factor binding","molecular_function",2,91,48,18684,0.0228900827414378,0.0583979561038176,8.55494505494506,"CTNNB1;NFE2L2"]
["GO:0016684","oxidoreductase activity, acting on peroxide as acceptor","molecular_function",1,91,5,18684,0.0241188808657227,0.0583979561038176,41.0637362637363,"CAT"]
["GO:0043120","tumor necrosis factor binding","molecular_function",1,91,5,18684,0.0241188808657227,0.0583979561038176,41.0637362637363,"TRAF2"]
["GO:0046870","cadmium ion binding","molecular_function",1,91,5,18684,0.0241188808657227,0.0583979561038176,41.0637362637363,"NOS3"]
["GO:0048406","nerve growth factor binding","molecular_function",1,91,5,18684,0.0241188808657227,0.0583979561038176,41.0637362637363,"NTRK1"]
["GO:0051525","NFAT protein binding","molecular_function",1,91,5,18684,0.0241188808657227,0.0583979561038176,41.0637362637363,"PPARA"]
["GO:0051575","5'-deoxyribose-5-phosphate lyase activity","molecular_function",1,91,5,18684,0.0241188808657227,0.0583979561038176,41.0637362637363,"XRCC6"]
["GO:0071532","ankyrin repeat binding","molecular_function",1,91,5,18684,0.0241188808657227,0.0583979561038176,41.0637362637363,"RELA"]
["GO:0101021","estrogen 2-hydroxylase activity","molecular_function",1,91,5,18684,0.0241188808657227,0.0583979561038176,41.0637362637363,"CYP1A1"]
["GO:0003743","translation initiation factor activity","molecular_function",2,91,51,18684,0.0256315741999478,0.0617443398880271,8.05171299288947,"EIF6;EIF2S1"]
["GO:0030374","nuclear receptor coactivator activity","molecular_function",2,91,54,18684,0.0284994325288926,0.0632666810562526,7.60439560439561,"NCOA2;PRKCB"]
["GO:0001006","RNA polymerase III type 3 promoter sequence-specific DNA binding","molecular_function",1,91,6,18684,0.0288731601012935,0.0632666810562526,34.2197802197802,"MTOR"]
["GO:0001225","RNA polymerase II transcription coactivator binding","molecular_function",1,91,6,18684,0.0288731601012935,0.0632666810562526,34.2197802197802,"RELA"]
["GO:0004046","aminoacylase activity","molecular_function",1,91,6,18684,0.0288731601012935,0.0632666810562526,34.2197802197802,"CAT"]
["GO:0004064","arylesterase activity","molecular_function",1,91,6,18684,0.0288731601012935,0.0632666810562526,34.2197802197802,"PON1"]
["GO:0005004","GPI-linked ephrin receptor activity","molecular_function",1,91,6,18684,0.0288731601012935,0.0632666810562526,34.2197802197802,"NTRK1"]
["GO:0005172","vascular endothelial growth factor receptor binding","molecular_function",1,91,6,18684,0.0288731601012935,0.0632666810562526,34.2197802197802,"VEGFA"]
["GO:0008131","primary amine oxidase activity","molecular_function",1,91,6,18684,0.0288731601012935,0.0632666810562526,34.2197802197802,"VCAM1"]
["GO:0031727","CCR2 chemokine receptor binding","molecular_function",1,91,6,18684,0.0288731601012935,0.0632666810562526,34.2197802197802,"CCR2"]
["GO:0031730","CCR5 chemokine receptor binding","molecular_function",1,91,6,18684,0.0288731601012935,0.0632666810562526,34.2197802197802,"JAK1"]
["GO:0032451","demethylase activity","molecular_function",1,91,6,18684,0.0288731601012935,0.0632666810562526,34.2197802197802,"CYP1A1"]
["GO:0043546","molybdopterin cofactor binding","molecular_function",1,91,6,18684,0.0288731601012935,0.0632666810562526,34.2197802197802,"XDH"]
["GO:0050544","arachidonic acid binding","molecular_function",1,91,6,18684,0.0288731601012935,0.0632666810562526,34.2197802197802,"PPARG"]
["GO:0055056","D-glucose transmembrane transporter activity","molecular_function",1,91,6,18684,0.0288731601012935,0.0632666810562526,34.2197802197802,"SLC2A4"]
["GO:0003684","damaged DNA binding","molecular_function",2,91,57,18684,0.0314894889800414,0.0673872405042206,7.20416425679584,"BRCA1;XRCC6"]
["GO:0050660","flavin adenine dinucleotide binding","molecular_function",2,91,58,18684,0.0325126223883431,0.0673872405042206,7.07995452823039,"XDH;NOS3"]
["GO:0042277","peptide binding","molecular_function",2,91,59,18684,0.033548730932523,0.0673872405042206,6.95995529893835,"RELA;PPARG"]
["GO:0001162","RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding","molecular_function",1,91,7,18684,0.0336045308278583,0.0673872405042206,29.331240188383,"NCOA2"]
["GO:0001221","transcription coregulator binding","molecular_function",1,91,7,18684,0.0336045308278583,0.0673872405042206,29.331240188383,"NFE2L2"]
["GO:0005138","interleukin-6 receptor binding","molecular_function",1,91,7,18684,0.0336045308278583,0.0673872405042206,29.331240188383,"IL6"]
["GO:0008391","arachidonic acid monooxygenase activity","molecular_function",1,91,7,18684,0.0336045308278583,0.0673872405042206,29.331240188383,"CYP1A1"]
["GO:0008603","cAMP-dependent protein kinase regulator activity","molecular_function",1,91,7,18684,0.0336045308278583,0.0673872405042206,29.331240188383,"PRKAG2"]
["GO:0010485","H4 histone acetyltransferase activity","molecular_function",1,91,7,18684,0.0336045308278583,0.0673872405042206,29.331240188383,"BRCA2"]
["GO:0050693","LBD domain binding","molecular_function",1,91,7,18684,0.0336045308278583,0.0673872405042206,29.331240188383,"PPARG"]
["GO:0001849","complement component C1q complex binding","molecular_function",1,91,8,18684,0.0383131022094862,0.0720896281374512,25.6648351648352,"CRP"]
["GO:0004862","cAMP-dependent protein kinase inhibitor activity","molecular_function",1,91,8,18684,0.0383131022094862,0.0720896281374512,25.6648351648352,"PRKAG2"]
["GO:0005113","patched binding","molecular_function",1,91,8,18684,0.0383131022094862,0.0720896281374512,25.6648351648352,"CCNB1"]
["GO:0030235","nitric-oxide synthase regulator activity","molecular_function",1,91,8,18684,0.0383131022094862,0.0720896281374512,25.6648351648352,"AKT1"]
["GO:0070878","primary miRNA binding","molecular_function",1,91,8,18684,0.0383131022094862,0.0720896281374512,25.6648351648352,"STAT3"]
["GO:0097371","MDM2/MDM4 family protein binding","molecular_function",1,91,8,18684,0.0383131022094862,0.0720896281374512,25.6648351648352,"PPARA"]
["GO:0005518","collagen binding","molecular_function",2,91,65,18684,0.040029669654757,0.0748725077320925,6.31749788672866,"MMP9;SPARC"]
["GO:0031490","chromatin DNA binding","molecular_function",2,91,66,18684,0.0411525318030305,0.0764920758759111,6.22177822177822,"RELA;STAT3"]
["GO:0003691","double-stranded telomeric DNA binding","molecular_function",1,91,9,18684,0.0429989828958718,0.0764920758759111,22.8131868131868,"XRCC6"]
["GO:0005131","growth hormone receptor binding","molecular_function",1,91,9,18684,0.0429989828958718,0.0764920758759111,22.8131868131868,"JAK1"]
["GO:0008140","cAMP response element binding protein binding","molecular_function",1,91,9,18684,0.0429989828958718,0.0764920758759111,22.8131868131868,"DDIT3"]
["GO:0017162","aryl hydrocarbon receptor binding","molecular_function",1,91,9,18684,0.0429989828958718,0.0764920758759111,22.8131868131868,"NCOA2"]
["GO:0034618","arginine binding","molecular_function",1,91,9,18684,0.0429989828958718,0.0764920758759111,22.8131868131868,"NOS3"]
["GO:0043184","vascular endothelial growth factor receptor 2 binding","molecular_function",1,91,9,18684,0.0429989828958718,0.0764920758759111,22.8131868131868,"VEGFA"]
["GO:0061575","cyclin-dependent protein serine/threonine kinase activator activity","molecular_function",1,91,9,18684,0.0429989828958718,0.0764920758759111,22.8131868131868,"CCNB1"]
["GO:0001094","TFIID-class transcription factor complex binding","molecular_function",1,91,10,18684,0.0476622810247322,0.0804008683476973,20.5318681318681,"AHR"]
["GO:0031419","cobalamin binding","molecular_function",1,91,10,18684,0.0476622810247322,0.0804008683476973,20.5318681318681,"CD320"]
["GO:0043560","insulin receptor substrate binding","molecular_function",1,91,10,18684,0.0476622810247322,0.0804008683476973,20.5318681318681,"PRKCD"]
["GO:0045294","alpha-catenin binding","molecular_function",1,91,10,18684,0.0476622810247322,0.0804008683476973,20.5318681318681,"CTNNB1"]
["GO:0043522","leucine zipper domain binding","molecular_function",1,91,11,18684,0.052303104224194,0.0854103368635155,18.6653346653347,"DDIT3"]
["GO:0070492","oligosaccharide binding","molecular_function",1,91,11,18684,0.052303104224194,0.0854103368635155,18.6653346653347,"SELE"]
["GO:0001618","virus receptor activity","molecular_function",2,91,78,18684,0.0555101794998862,0.0897737024456025,5.26458157227388,"CD80;BSG"]
["GO:0004175","endopeptidase activity","molecular_function",2,91,79,18684,0.0567762134857625,0.0897737024456025,5.19794129920712,"MMP2;MMP9"]
["GO:0008353","RNA polymerase II CTD heptapeptide repeat kinase activity","molecular_function",1,91,12,18684,0.0569215596151652,0.0897737024456025,17.1098901098901,"MAPK1"]
["GO:0019887","protein kinase regulator activity","molecular_function",1,91,12,18684,0.0569215596151652,0.0897737024456025,17.1098901098901,"PRKAG2"]
["GO:0042301","phosphate ion binding","molecular_function",1,91,12,18684,0.0569215596151652,0.0897737024456025,17.1098901098901,"RELA"]
["GO:0042805","actinin binding","molecular_function",1,91,12,18684,0.0569215596151652,0.0897737024456025,17.1098901098901,"RELA"]
["GO:0043023","ribosomal large subunit binding","molecular_function",1,91,12,18684,0.0569215596151652,0.0897737024456025,17.1098901098901,"EIF6"]
["GO:0043295","glutathione binding","molecular_function",1,91,12,18684,0.0569215596151652,0.0897737024456025,17.1098901098901,"PTGES"]
["GO:0046790","virion binding","molecular_function",1,91,12,18684,0.0569215596151652,0.0897737024456025,17.1098901098901,"CRP"]
["GO:0005068","transmembrane receptor protein tyrosine kinase adaptor activity","molecular_function",1,91,13,18684,0.0615177538136986,0.09450046503794,15.7937447168216,"IRS1"]
["GO:0001227","DNA-binding transcription repressor activity, RNA polymerase II-specific","molecular_function",4,91,305,18684,0.0618329315001839,0.094830554312123,2.69270401729418,"RELA;PPARG;MYC;PPARA"]
["GO:0008013","beta-catenin binding","molecular_function",2,91,85,18684,0.0645800871663965,0.0989634885183596,4.83102779573368,"FOXO1;CTNNB1"]
["GO:0070411","I-SMAD binding","molecular_function",1,91,14,18684,0.066091792933347,0.0998239460359099,14.6656200941915,"CTNNB1"]
["GO:0045296","cadherin binding","molecular_function",4,91,316,18684,0.0685462070145224,0.103365930992394,2.59897064960356,"STAT1;CTNNB1;PTPN1;BSG"]
["GO:0004713","protein tyrosine kinase activity","molecular_function",2,91,89,18684,0.069971444065,0.10347590462662,4.6139029509816,"NTRK1;JAK1"]
["GO:0005161","platelet-derived growth factor receptor binding","molecular_function",1,91,15,18684,0.0706437825875019,0.10347590462662,13.6879120879121,"VEGFA"]
["GO:0005355","glucose transmembrane transporter activity","molecular_function",1,91,15,18684,0.0706437825875019,0.10347590462662,13.6879120879121,"SLC2A4"]
["GO:0016208","AMP binding","molecular_function",1,91,15,18684,0.0706437825875019,0.10347590462662,13.6879120879121,"PRKAG2"]
["GO:0032794","GTPase activating protein binding","molecular_function",1,91,15,18684,0.0706437825875019,0.10347590462662,13.6879120879121,"AKT1"]
["GO:0043274","phospholipase binding","molecular_function",1,91,15,18684,0.0706437825875019,0.10347590462662,13.6879120879121,"SELE"]
["GO:0045236","CXCR chemokine receptor binding","molecular_function",1,91,15,18684,0.0706437825875019,0.10347590462662,13.6879120879121,"CXCL8"]
["GO:0051393","alpha-actinin binding","molecular_function",1,91,15,18684,0.0706437825875019,0.10347590462662,13.6879120879121,"PPARG"]
["GO:0004197","cysteine-type endopeptidase activity","molecular_function",2,91,90,18684,0.071341780073981,0.104417419597444,4.56263736263736,"CASP9;CASP3"]
["GO:0005159","insulin-like growth factor receptor binding","molecular_function",1,91,16,18684,0.0751738278917243,0.107692203441857,12.8324175824176,"IRS1"]
["GO:0010181","FMN binding","molecular_function",1,91,16,18684,0.0751738278917243,0.107692203441857,12.8324175824176,"NOS3"]
["GO:0016709","oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen","molecular_function",1,91,16,18684,0.0751738278917243,0.107692203441857,12.8324175824176,"NOS3"]
["GO:0004950","chemokine receptor activity","molecular_function",1,91,17,18684,0.0796820334660687,0.112028792032964,12.0775694893342,"CCR2"]
["GO:0030169","low-density lipoprotein particle binding","molecular_function",1,91,17,18684,0.0796820334660687,0.112028792032964,12.0775694893342,"CRP"]
["GO:0045182","translation regulator activity","molecular_function",1,91,17,18684,0.0796820334660687,0.112028792032964,12.0775694893342,"MTOR"]
["GO:0046965","retinoid X receptor binding","molecular_function",1,91,17,18684,0.0796820334660687,0.112028792032964,12.0775694893342,"PPARG"]
["GO:0070063","RNA polymerase binding","molecular_function",1,91,17,18684,0.0796820334660687,0.112028792032964,12.0775694893342,"BRCA1"]
["GO:0070064","proline-rich region binding","molecular_function",1,91,17,18684,0.0796820334660687,0.112028792032964,12.0775694893342,"CCND1"]
["GO:0038023","signaling receptor activity","molecular_function",3,91,209,18684,0.0821373090029937,0.115309317984158,2.94715810505284,"ADIPOR1;ADIPOR2;TNFRSF10A"]
["GO:0004190","aspartic-type endopeptidase activity","molecular_function",1,91,18,18684,0.0841685034373864,0.116346959064399,11.4065934065934,"CASP3"]
["GO:0016209","antioxidant activity","molecular_function",1,91,18,18684,0.0841685034373864,0.116346959064399,11.4065934065934,"CAT"]
["GO:0140416","transcription regulator inhibitor activity","molecular_function",1,91,18,18684,0.0841685034373864,0.116346959064399,11.4065934065934,"DDIT3"]
["GO:0051087","chaperone binding","molecular_function",2,91,100,18684,0.0855083833448953,0.118026534967297,4.10637362637363,"BAX;BIRC5"]
["GO:0005537","mannose binding","molecular_function",1,91,19,18684,0.0886333414416292,0.120753349183084,10.8062463851938,"BSG"]
["GO:0016712","oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen","molecular_function",1,91,20,18684,0.0930766506261355,0.125809825828465,10.2659340659341,"CYP1B1"]
["GO:0016922","nuclear receptor binding","molecular_function",1,91,20,18684,0.0930766506261355,0.125809825828465,10.2659340659341,"NCOA2"]
["GO:0005524","ATP binding","molecular_function",11,91,1459,18684,0.0969220922776638,0.129655223020927,1.54798183310863,"AKT1;MAPK3;MAPK1;MAPK8;PRKCD;XRCC6;PRKCB;PRKAG2;NTRK1;JAK1;MTOR"]
["GO:0043027","cysteine-type endopeptidase inhibitor activity involved in apoptotic process","molecular_function",1,91,21,18684,0.0974985336519083,0.129655223020927,9.77708006279435,"BIRC5"]
["GO:0051537","2 iron, 2 sulfur cluster binding","molecular_function",1,91,21,18684,0.0974985336519083,0.129655223020927,9.77708006279435,"XDH"]
["GO:0003707","steroid hormone receptor activity","molecular_function",1,91,22,18684,0.101899092695881,0.133720460990917,9.33266733266733,"PPARA"]
["GO:0004602","glutathione peroxidase activity","molecular_function",1,91,22,18684,0.101899092695881,0.133720460990917,9.33266733266733,"PTGES"]
["GO:0030742","GTP-dependent protein binding","molecular_function",1,91,22,18684,0.101899092695881,0.133720460990917,9.33266733266733,"CDC42"]
["GO:0033691","sialic acid binding","molecular_function",1,91,22,18684,0.101899092695881,0.133720460990917,9.33266733266733,"SELE"]
["GO:0043548","phosphatidylinositol 3-kinase binding","molecular_function",1,91,22,18684,0.101899092695881,0.133720460990917,9.33266733266733,"IRS1"]
["GO:0098632","cell-cell adhesion mediator activity","molecular_function",1,91,22,18684,0.101899092695881,0.133720460990917,9.33266733266733,"BSG"]
["GO:0003713","transcription coactivator activity","molecular_function",3,91,231,18684,0.103116284895907,0.135223921455035,2.6664763807621,"NCOA2;CTNNB1;BRCA1"]
["GO:0016493","C-C chemokine receptor activity","molecular_function",1,91,23,18684,0.106278429453178,0.137652404175315,8.92689918776875,"CCR2"]
["GO:0050750","low-density lipoprotein particle receptor binding","molecular_function",1,91,23,18684,0.106278429453178,0.137652404175315,8.92689918776875,"CRP"]
["GO:0016491","oxidoreductase activity","molecular_function",2,91,115,18684,0.108160880527807,0.139803298071143,3.5707596751075,"CYP1A1;NOS3"]
["GO:0019957","C-C chemokine binding","molecular_function",1,91,24,18684,0.110636645139356,0.141743831950219,8.55494505494506,"CCR2"]
["GO:0008144","drug binding","molecular_function",1,91,25,18684,0.114973840492642,0.146506423430988,8.21274725274725,"PPARA"]
["GO:0008139","nuclear localization sequence binding","molecular_function",1,91,26,18684,0.119290115776161,0.15058585376016,7.89687235841082,"NFKBIA"]
["GO:0017025","TBP-class protein binding","molecular_function",1,91,26,18684,0.119290115776161,0.15058585376016,7.89687235841082,"AHR"]
["GO:0042162","telomeric DNA binding","molecular_function",1,91,26,18684,0.119290115776161,0.15058585376016,7.89687235841082,"XRCC6"]
["GO:0106310","protein serine kinase activity","molecular_function",3,91,248,18684,0.120635037883136,0.15218202577519,2.48369372562921,"AKT1;PRKCD;MTOR"]
["GO:0004364","glutathione transferase activity","molecular_function",1,91,27,18684,0.123585570780147,0.154461542858729,7.60439560439561,"PTGES"]
["GO:0035035","histone acetyltransferase binding","molecular_function",1,91,27,18684,0.123585570780147,0.154461542858729,7.60439560439561,"STAT1"]
["GO:0046875","ephrin receptor binding","molecular_function",1,91,27,18684,0.123585570780147,0.154461542858729,7.60439560439561,"PTPN1"]
["GO:0001968","fibronectin binding","molecular_function",1,91,28,18684,0.127860304824152,0.158028651256517,7.33281004709576,"VEGFA"]
["GO:0003785","actin monomer binding","molecular_function",1,91,28,18684,0.127860304824152,0.158028651256517,7.33281004709576,"NOS3"]
["GO:0004712","protein serine/threonine/tyrosine kinase activity","molecular_function",1,91,28,18684,0.127860304824152,0.158028651256517,7.33281004709576,"AKT1"]
["GO:0030159","signaling receptor complex adaptor activity","molecular_function",1,91,28,18684,0.127860304824152,0.158028651256517,7.33281004709576,"IRS1"]
["GO:0043015","gamma-tubulin binding","molecular_function",1,91,28,18684,0.127860304824152,0.158028651256517,7.33281004709576,"BRCA2"]
["GO:0050681","androgen receptor binding","molecular_function",1,91,28,18684,0.127860304824152,0.158028651256517,7.33281004709576,"PRKCB"]
["GO:0030295","protein kinase activator activity","molecular_function",1,91,29,18684,0.13211441675924,0.161800535330827,7.07995452823039,"PRKAG2"]
["GO:0043325","phosphatidylinositol-3,4-bisphosphate binding","molecular_function",1,91,29,18684,0.13211441675924,0.161800535330827,7.07995452823039,"AKT1"]
["GO:0071889","14-3-3 protein binding","molecular_function",1,91,31,18684,0.140561167377574,0.16940800988591,6.62318326834456,"AKT1"]
["GO:0008289","lipid binding","molecular_function",2,91,138,18684,0.145473094556905,0.174328023958876,2.97563306258958,"BAX;PPARA"]
["GO:0005178","integrin binding","molecular_function",2,91,140,18684,0.148835377297256,0.177790535644095,2.9331240188383,"IL1B;VCAM1"]
["GO:0005154","epidermal growth factor receptor binding","molecular_function",1,91,33,18684,0.148926604156661,0.177790535644095,6.22177822177822,"TGFA"]
["GO:0031624","ubiquitin conjugating enzyme binding","molecular_function",1,91,33,18684,0.148926604156661,0.177790535644095,6.22177822177822,"PPARA"]
["GO:0071949","FAD binding","molecular_function",1,91,33,18684,0.148926604156661,0.177790535644095,6.22177822177822,"XDH"]
["GO:0004860","protein kinase inhibitor activity","molecular_function",1,91,34,18684,0.153079072068395,0.182172766067548,6.0387847446671,"CDKN1A"]
["GO:0005246","calcium channel regulator activity","molecular_function",1,91,34,18684,0.153079072068395,0.182172766067548,6.0387847446671,"PRKCB"]
["GO:0004402","histone acetyltransferase activity","molecular_function",1,91,36,18684,0.161323987366686,0.190545696508684,5.7032967032967,"BRCA2"]
["GO:0008094","DNA-dependent ATPase activity","molecular_function",1,91,36,18684,0.161323987366686,0.190545696508684,5.7032967032967,"XRCC6"]
["GO:0048018","receptor ligand activity","molecular_function",1,91,36,18684,0.161323987366686,0.190545696508684,5.7032967032967,"VEGFA"]
["GO:0042169","SH2 domain binding","molecular_function",1,91,38,18684,0.169489510592132,0.199194943772356,5.40312319259688,"IRS1"]
["GO:0005547","phosphatidylinositol-3,4,5-trisphosphate binding","molecular_function",1,91,39,18684,0.17354273672836,0.202698774029233,5.26458157227388,"AKT1"]
["GO:0043531","ADP binding","molecular_function",1,91,39,18684,0.17354273672836,0.202698774029233,5.26458157227388,"PRKAG2"]
["GO:0004888","transmembrane signaling receptor activity","molecular_function",2,91,157,18684,0.177995872871009,0.207515533661577,2.61552460278575,"SELE;PECAM1"]
["GO:0008201","heparin binding","molecular_function",2,91,164,18684,0.190253248994166,0.217777780779641,2.50388635754489,"VEGFA;MPO"]
["GO:0042393","histone binding","molecular_function",2,91,164,18684,0.190253248994166,0.217777780779641,2.50388635754489,"STAT1;PRKCB"]
["GO:0046332","SMAD binding","molecular_function",1,91,48,18684,0.209152460265458,0.236547429642333,4.27747252747253,"CTNNB1"]
["GO:0008009","chemokine activity","molecular_function",1,91,49,18684,0.21301418628584,0.240339991805802,4.19017716976901,"CXCL8"]
["GO:0000987","cis-regulatory region sequence-specific DNA binding","molecular_function",1,91,50,18684,0.216857261630514,0.243803259062605,4.10637362637363,"AHR"]
["GO:0015485","cholesterol binding","molecular_function",1,91,50,18684,0.216857261630514,0.243803259062605,4.10637362637363,"NR1H3"]
["GO:0003714","transcription corepressor activity","molecular_function",2,91,183,18684,0.224028346028178,0.251038711068275,2.24392001441182,"CCND1;RUNX1T1"]
["GO:0003678","DNA helicase activity","molecular_function",1,91,52,18684,0.224487816190615,0.251038711068275,3.94843617920541,"XRCC6"]
["GO:0005507","copper ion binding","molecular_function",1,91,52,18684,0.224487816190615,0.251038711068275,3.94843617920541,"IL1A"]
["GO:0001085","RNA polymerase II transcription factor binding","molecular_function",1,91,53,18684,0.228275472305184,0.254371784401358,3.87393738337135,"CTNNB1"]
["GO:0004714","transmembrane receptor protein tyrosine kinase activity","molecular_function",1,91,54,18684,0.232044831546247,0.257509845336826,3.8021978021978,"NTRK1"]
["GO:0015631","tubulin binding","molecular_function",1,91,56,18684,0.239529008629245,0.264573221564195,3.66640502354788,"BRCA1"]
["GO:0043621","protein self-association","molecular_function",1,91,56,18684,0.239529008629245,0.264573221564195,3.66640502354788,"PPARG"]
["GO:0097110","scaffold protein binding","molecular_function",1,91,58,18684,0.246941041764942,0.271807630953146,3.5399772641152,"MAPK3"]
["GO:1990841","promoter-specific chromatin binding","molecular_function",1,91,58,18684,0.246941041764942,0.271807630953146,3.5399772641152,"STAT1"]
["GO:0005516","calmodulin binding","molecular_function",2,91,198,18684,0.251014595148386,0.275489610809982,2.07392607392607,"AKT1;NOS3"]
["GO:0030971","receptor tyrosine kinase binding","molecular_function",1,91,60,18684,0.25428161873373,0.277945977471377,3.42197802197802,"PTPN1"]
["GO:0009055","electron transfer activity","molecular_function",1,91,66,18684,0.275881393545551,0.299478596552605,3.11088911088911,"XDH"]
["GO:0050839","cell adhesion molecule binding","molecular_function",1,91,66,18684,0.275881393545551,0.299478596552605,3.11088911088911,"VCAM1"]
["GO:0004842","ubiquitin-protein transferase activity","molecular_function",2,91,229,18684,0.306931978121074,0.328121625795842,1.79317625605835,"BRCA1;TRAF2"]
["GO:0046872","metal ion binding","molecular_function",13,91,2294,18684,0.323710628746714,0.344477658390566,1.16353219579026,"PTGS1;PTGS2;CDKN1A;CAT;RUNX1T1;SELE;PRKCD;BIRC5;MPO;KLF10;ADIPOR1;ADIPOR2;JAK1"]
["GO:0106311","protein threonine kinase activity","molecular_function",2,91,247,18684,0.339112897310707,0.35844745042736,1.66249944387596,"AKT1;MTOR"]
["GO:0008017","microtubule binding","molecular_function",2,91,253,18684,0.349748520787687,0.369070565183881,1.62307257959432,"BIRC5;BCL2L11"]
["GO:0030674","protein-macromolecule adaptor activity","molecular_function",1,91,89,18684,0.353098089476125,0.371982444122201,2.3069514754908,"TRAF2"]
["GO:0005179","hormone activity","molecular_function",1,91,98,18684,0.38104477821233,0.398757983176268,2.0950885848845,"EDN1"]
["GO:0004725","protein tyrosine phosphatase activity","molecular_function",1,91,102,18684,0.393079016888563,0.410216567845625,2.01292824822237,"PTPN1"]
["GO:0047485","protein N-terminus binding","molecular_function",1,91,103,18684,0.396051237826198,0.412862674051455,1.99338525552118,"RELA"]
["GO:0003697","single-stranded DNA binding","molecular_function",1,91,107,18684,0.407796845345233,0.424638675411804,1.91886618054842,"BRCA2"]
["GO:0005543","phospholipid binding","molecular_function",1,91,110,18684,0.416457523618129,0.432941823618407,1.86653346653347,"PON1"]
["GO:0005509","calcium ion binding","molecular_function",4,91,705,18684,0.451015539198803,0.466304201544525,1.16492868833294,"CRP;PON1;SPARC;CD320"]
["GO:0017124","SH3 domain binding","molecular_function",1,91,127,18684,0.46322017095898,0.477616872019319,1.61668253006836,"CASP9"]
["GO:0044325","ion channel binding","molecular_function",1,91,128,18684,0.46585243718966,0.479546520808736,1.6040521978022,"CTNNB1"]
["GO:0000977","RNA polymerase II transcription regulatory region sequence-specific DNA binding","molecular_function",2,91,331,18684,0.481208201380982,0.493917360783491,1.2405962617443,"RELA;SREBF1"]
["GO:0005201","extracellular matrix structural constituent","molecular_function",1,91,137,18684,0.488975607298217,0.501166869051994,1.49867650597578,"SPARC"]
["GO:1990837","sequence-specific double-stranded DNA binding","molecular_function",3,91,555,18684,0.510142675852092,0.52088542118591,1.10983070983071,"AHR;KLF10;SREBF1"]
["GO:0005102","signaling receptor binding","molecular_function",2,91,350,18684,0.510792479035121,0.521267446225264,1.17324960753532,"PLAT;TNFSF10"]
["GO:0031267","small GTPase binding","molecular_function",1,91,190,18684,0.606386996448079,0.613196689991079,1.08062463851938,"BIRC5"]
["GO:0061630","ubiquitin protein ligase activity","molecular_function",1,91,287,18684,0.756369949461127,0.761200412150607,0.715396102155684,"CDC42"]
["GO:0003924","GTPase activity","molecular_function",1,91,317,18684,0.790070610303222,0.794270879363845,0.647693001005304,"CDC42"]
["GO:0005525","GTP binding","molecular_function",1,91,372,18684,0.84031694035939,0.842991689241171,0.551931939028713,"CDC42"]
["GO:0003723","RNA binding","molecular_function",4,91,1382,18684,0.912088186785139,0.913053870413286,0.594265358375344,"BRCA1;XRCC6;PTPN1;EIF2S1"]
["GO:0004930","G protein-coupled receptor activity","molecular_function",1,91,675,18684,0.965148870448997,0.965659531227012,0.304175824175824,"AGTR1"]

{"sheet":"S5(KEGG)","index":4,"n_rows":220,"n_cols":13,"rows_kept":220,"flags":["formulas_cached_only"]}
["id","Term","Classification_level1","Classification_level2","ListHits","ListTotal","PopHits","PopTotal","p-value","q-value","Enrichment_score","geneID","hyperlink_only_excel"]
["hsa00140","Steroid hormone biosynthesis","Metabolism","Lipid metabolism",2,83,61,7820,0.136627120816014,0.169047115585915,3.08907762196326,"CYP1A1;CYP1B1","hsa00140"]
["hsa00220","Arginine biosynthesis","Metabolism","Amino acid metabolism",1,83,22,7820,0.209483962333463,0.249331455168632,4.28258488499452,"NOS3","hsa00220"]
["hsa00230","Purine metabolism","Metabolism","Nucleotide metabolism",1,83,130,7820,0.753107463064167,0.770703431827348,0.724745134383689,"XDH","hsa00230"]
["hsa00232","Caffeine metabolism","Metabolism","Biosynthesis of other secondary metabolites",1,83,6,7820,0.0620361039054931,0.0838636219463147,15.7028112449799,"XDH","hsa00232"]
["hsa00330","Arginine and proline metabolism","Metabolism","Amino acid metabolism",2,83,51,7820,0.101714292765187,0.129508314625442,3.69477911646586,"ODC1;NOS3","hsa00330"]
["hsa00380","Tryptophan metabolism","Metabolism","Amino acid metabolism",3,83,42,7820,0.00982704500424927,0.0153723061137899,6.72977624784854,"CAT;CYP1A1;CYP1B1","hsa00380"]
["hsa00480","Glutathione metabolism","Metabolism","Metabolism of other amino acids",1,83,55,7820,0.445077253726068,0.492282417000045,1.71303395399781,"ODC1","hsa00480"]
["hsa00590","Arachidonic acid metabolism","Metabolism","Lipid metabolism",3,83,61,7820,0.0266951785996243,0.0384621323244587,4.63361643294489,"PTGS1;PTGS2;PTGES","hsa00590"]
["hsa00630","Glyoxylate and dicarboxylate metabolism","Metabolism","Carbohydrate metabolism",1,83,30,7820,0.274369557936103,0.319611346744715,3.14056224899598,"CAT","hsa00630"]
["hsa00830","Retinol metabolism","Metabolism","Metabolism of cofactors and vitamins",1,83,67,7820,0.512261860628189,0.560926737387867,1.40622190253552,"CYP1A1","hsa00830"]
["hsa00980","Metabolism of xenobiotics by cytochrome P450","Metabolism","Xenobiotics biodegradation and metabolism",2,83,75,7820,0.189010455100802,0.228692208105391,2.51244979919679,"CYP1A1;CYP1B1","hsa00980"]
["hsa00983","Drug metabolism - other enzymes","Metabolism","Xenobiotics biodegradation and metabolism",2,83,79,7820,0.204465579781472,0.244688316787663,2.38523715113619,"XDH;MPO","hsa00983"]
["hsa01521","EGFR tyrosine kinase inhibitor resistance","Human Diseases","Drug resistance: antineoplastic",15,83,79,7820,{"v":2.05358420234689e-15,"d":"2.05E-15"},{"v":3.21239243081406e-14,"d":"3.21E-14"},17.8892786335214,"STAT3;AKT1;VEGFA;BCL2;BCL2L1;BAX;MAPK3;MAPK1;IL6;PRKCB;HGF;JAK1;MTOR;BCL2L11;TGFA","hsa01521"]
["hsa01522","Endocrine resistance","Human Diseases","Drug resistance: antineoplastic",11,83,97,7820,{"v":4.64306344951905e-09,"d":"4.64E-09"},{"v":2.00783620752934e-08,"d":"2.01E-08"},10.6843870326668,"AKT1;CCND1;BCL2;CDKN1A;BAX;MMP2;MMP9;MAPK3;MAPK1;MAPK8;MTOR","hsa01522"]
["hsa01523","Antifolate resistance","Human Diseases","Drug resistance: antineoplastic",3,83,31,7820,0.00418305562690631,0.00710146652939909,9.11776136805286,"RELA;IL6;IL1B","hsa01523"]
["hsa01524","Platinum drug resistance","Human Diseases","Drug resistance: antineoplastic",11,83,72,7820,{"v":1.74575824995875e-10,"d":"1.75E-10"},{"v":1.15854865679081e-09,"d":"1.16E-09"},14.3942436412316,"AKT1;BCL2;BCL2L1;CDKN1A;BAX;CASP9;MAPK3;MAPK1;CASP3;BRCA1;BIRC5","hsa01524"]
["hsa03008","Ribosome biogenesis in eukaryotes","Genetic Information Processing","Translation",1,83,80,7820,0.575994076179645,0.615330256991914,1.17771084337349,"EIF6","hsa03008"]
["hsa03013","RNA transport","Genetic Information Processing","Translation",1,83,166,7820,0.833101166110923,0.840779517872314,0.567571490782407,"EIF2S1","hsa03013"]
["hsa03320","PPAR signaling pathway","Organismal Systems","Endocrine system",3,83,76,7820,0.0466107605586642,0.0641997268072167,3.71908687381103,"PPARG;PPARA;NR1H3","hsa03320"]
["hsa03440","Homologous recombination","Genetic Information Processing","Replication and repair",2,83,41,7820,0.0699402517353007,0.0931796418876896,4.59594475462827,"BRCA1;BRCA2","hsa03440"]
["hsa03450","Non-homologous end-joining","Genetic Information Processing","Replication and repair",1,83,13,7820,0.129618905858934,0.161287161267651,7.24745134383689,"XRCC6","hsa03450"]
["hsa03460","Fanconi anemia pathway","Genetic Information Processing","Replication and repair",2,83,54,7820,0.111904773252307,0.140845662886524,3.48951360999554,"BRCA1;BRCA2","hsa03460"]
["hsa04010","MAPK signaling pathway","Environmental Information Processing","Signal transduction",17,83,294,7820,{"v":8.16052996892687e-09,"d":"8.16E-09"},{"v":3.13536151437717e-08,"d":"3.14E-08"},5.4479141054012,"RELA;AKT1;VEGFA;MAPK3;MAPK1;CASP3;MAPK8;MYC;IL1B;PRKCB;HGF;DDIT3;IL1A;NTRK1;TRAF2;CDC42;TGFA","hsa04010"]
["hsa04012","ErbB signaling pathway","Environmental Information Processing","Signal transduction",9,83,85,7820,{"v":2.3517951851382e-07,"d":"2.35E-07"},{"v":6.77688349401664e-07,"d":"6.78E-07"},9.97590361445783,"AKT1;CDKN1A;MAPK3;MAPK1;MAPK8;MYC;PRKCB;MTOR;TGFA","hsa04012"]
["hsa04014","Ras signaling pathway","Environmental Information Processing","Signal transduction",12,83,232,7820,{"v":5.25412237550754e-06,"d":"5.25E-06"},{"v":1.2785031113735e-05,"d":"1.28E-05"},4.87328624844204,"RELA;AKT1;VEGFA;BCL2L1;MAPK3;MAPK1;MAPK8;PRKCB;HGF;NTRK1;CDC42;TGFA","hsa04014"]
["hsa04015","Rap1 signaling pathway","Environmental Information Processing","Signal transduction",8,83,210,7820,0.00165825601157232,0.00307761073334184,3.58921399885255,"AKT1;VEGFA;MAPK3;MAPK1;CTNNB1;PRKCB;HGF;CDC42","hsa04015"]
["hsa04020","Calcium signaling pathway","Environmental Information Processing","Signal transduction",6,83,240,7820,0.04170197007863,0.0578020977672149,2.35542168674699,"VEGFA;PRKCB;NOS3;HGF;NTRK1;AGTR1","hsa04020"]
["hsa04022","cGMP-PKG signaling pathway","Environmental Information Processing","Signal transduction",6,83,167,7820,0.00843978920225711,0.0132972218366497,3.38503715460645,"AKT1;MAPK3;MAPK1;NOS3;AGTR1;IRS1","hsa04022"]
["hsa04024","cAMP signaling pathway","Environmental Information Processing","Signal transduction",8,83,216,7820,0.0019811170109396,0.00361553854496477,3.48951360999554,"RELA;AKT1;MAPK3;MAPK1;MAPK8;NFKBIA;EDN1;PPARA","hsa04024"]
["hsa04060","Cytokine-cytokine receptor interaction","Environmental Information Processing","Signaling molecules and interaction",8,83,295,7820,0.0126681500053513,0.0194008730851184,2.55503369409843,"IL10;IL6;IL1B;CXCL8;IL1A;CCR2;TNFSF10;TNFRSF10A","hsa04060"]
["hsa04061","Viral protein interaction with cytokine and cytokine receptor","Environmental Information Processing","Signaling molecules and interaction",6,83,100,7820,0.000641282049204064,0.00125393543549723,5.65301204819277,"IL10;IL6;CXCL8;CCR2;TNFSF10;TNFRSF10A","hsa04061"]
["hsa04062","Chemokine signaling pathway","Organismal Systems","Immune system",12,83,192,7820,{"v":7.17430393657061e-07,"d":"7.17E-07"},{"v":1.91606410013288e-06,"d":"1.92E-06"},5.88855421686747,"RELA;STAT3;AKT1;MAPK3;MAPK1;NFKBIA;STAT1;PRKCD;CXCL8;PRKCB;CCR2;CDC42","hsa04062"]
["hsa04064","NF-kappa B signaling pathway","Environmental Information Processing","Signal transduction",13,83,104,7820,{"v":4.63810606665752e-11,"d":"4.64E-11"},{"v":3.76201936517777e-10,"d":"3.76E-10"},11.7771084337349,"PTGS2;RELA;BCL2;BCL2L1;PLAU;NFKBIA;IL1B;VCAM1;CXCL8;PRKCB;BCL2A1;CFLAR;TRAF2","hsa04064"]
["hsa04066","HIF-1 signaling pathway","Environmental Information Processing","Signal transduction",13,83,109,7820,{"v":8.49953786400114e-11,"d":"8.50E-11"},{"v":6.20466264072083e-10,"d":"6.20E-10"},11.2368741019122,"RELA;STAT3;AKT1;VEGFA;BCL2;CDKN1A;MAPK3;MAPK1;IL6;EDN1;PRKCB;NOS3;MTOR","hsa04066"]
["hsa04068","FoxO signaling pathway","Environmental Information Processing","Signal transduction",17,83,131,7820,{"v":1.80083047157444e-14,"d":"1.80E-14"},{"v":2.46488670796752e-13,"d":"2.46E-13"},12.226616389221,"STAT3;AKT1;CCND1;CDKN1A;MAPK3;MAPK1;IL10;IL6;MAPK8;CAT;FOXO1;CCNB1;PRKAG2;SLC2A4;IRS1;BCL2L11;TNFSF10","hsa04068"]
["hsa04070","Phosphatidylinositol signaling system","Environmental Information Processing","Signal transduction",1,83,97,7820,0.647069040784806,0.668434527980531,0.971307912060614,"PRKCB","hsa04070"]
["hsa04071","Sphingolipid signaling pathway","Environmental Information Processing","Signal transduction",10,83,119,7820,{"v":4.3477193255119e-07,"d":"4.35E-07"},{"v":1.22070581062449e-06,"d":"1.22E-06"},7.91738382099828,"RELA;AKT1;BCL2;BAX;MAPK3;MAPK1;MAPK8;PRKCB;NOS3;TRAF2","hsa04071"]
["hsa04072","Phospholipase D signaling pathway","Environmental Information Processing","Signal transduction",6,83,148,7820,0.00473642628218724,0.00779907786315042,3.81960273526539,"AKT1;MAPK3;MAPK1;CXCL8;AGTR1;MTOR","hsa04072"]
["hsa04080","Neuroactive ligand-receptor interaction","Environmental Information Processing","Signaling molecules and interaction",2,83,341,7820,0.8831076815666,0.887158634234336,0.55259159806381,"EDN1;AGTR1","hsa04080"]
["hsa04110","Cell cycle","Cellular Processes","Cell growth and death",5,83,124,7820,0.0100302831738495,0.0154692395427679,3.79906723668869,"CCND1;CDKN1A;MYC;CCNB1;CCNE1","hsa04110"]
["hsa04114","Oocyte meiosis","Cellular Processes","Cell growth and death",4,83,129,7820,0.0478938794340228,0.0655547474753188,2.92145325487999,"MAPK3;MAPK1;CCNB1;CCNE1","hsa04114"]
["hsa04115","p53 signaling pathway","Cellular Processes","Cell growth and death",10,83,73,7820,{"v":3.7647536324303e-09,"d":"3.76E-09"},{"v":1.7923500989179e-08,"d":"1.79E-08"},12.9064202013534,"CCND1;BCL2;BCL2L1;CDKN1A;BAX;CASP9;CASP3;CCNB1;CCNE1;TNFRSF10A","hsa04115"]
["hsa04120","Ubiquitin mediated proteolysis","Genetic Information Processing","Folding, sorting and degradation",1,83,139,7820,0.776092082531722,0.790531004997428,0.677819190430788,"BRCA1","hsa04120"]
["hsa04136","Autophagy - other","Cellular Processes","Transport and catabolism",1,83,32,7820,0.289750892997652,0.330497112325447,2.94427710843374,"MTOR","hsa04136"]
["hsa04137","Mitophagy - animal","Cellular Processes","Transport and catabolism",3,83,68,7820,0.0352732507468911,0.0494655538428584,4.1566265060241,"RELA;BCL2L1;MAPK8","hsa04137"]
["hsa04140","Autophagy - animal","Cellular Processes","Transport and catabolism",11,83,137,7820,{"v":1.75636231209606e-07,"d":"1.76E-07"},{"v":5.19788305877076e-07,"d":"5.20E-07"},7.56485797203412,"AKT1;BCL2;BCL2L1;MAPK3;MAPK1;MAPK8;PRKCD;IRS1;CFLAR;MTOR;EIF2S1","hsa04140"]
["hsa04141","Protein processing in endoplasmic reticulum","Genetic Information Processing","Folding, sorting and degradation",7,83,170,7820,0.00210145688316518,0.0038034632844064,3.87951807228916,"BCL2;BAX;MAPK8;DDIT3;NFE2L2;EIF2S1;TRAF2","hsa04141"]
["hsa04144","Endocytosis","Cellular Processes","Transport and catabolism",1,83,251,7820,0.934276143231454,0.934276143231454,0.375366005856094,"CDC42","hsa04144"]
["hsa04145","Phagosome","Cellular Processes","Transport and catabolism",1,83,151,7820,0.803479919288052,0.814639362611497,0.623952764701189,"MPO","hsa04145"]
["hsa04146","Peroxisome","Cellular Processes","Transport and catabolism",2,83,82,7820,0.216149713982465,0.255874526281945,2.29797237731413,"XDH;CAT","hsa04146"]
["hsa04150","mTOR signaling pathway","Environmental Information Processing","Signal transduction",6,83,155,7820,0.00592210184443833,0.00953632576420583,3.64710454722114,"AKT1;MAPK3;MAPK1;PRKCB;IRS1;MTOR","hsa04150"]
["hsa04151","PI3K-Akt signaling pathway","Environmental Information Processing","Signal transduction",22,83,354,7820,{"v":7.73081046494009e-12,"d":"7.73E-12"},{"v":7.07754162770211e-11,"d":"7.08E-11"},5.85528554897556,"RELA;AKT1;VEGFA;CCND1;BCL2;BCL2L1;CDKN1A;CASP9;MAPK3;MAPK1;IL6;MYC;BRCA1;NOS3;HGF;CCNE1;NTRK1;JAK1;IRS1;MTOR;BCL2L11;TGFA","hsa04151"]
["hsa04152","AMPK signaling pathway","Environmental Information Processing","Signal transduction",11,83,120,7820,{"v":4.4524666348523e-08,"d":"4.45E-08"},{"v":1.50013875851177e-07,"d":"1.50E-07"},8.63654618473896,"AKT1;CCND1;FOXO1;PPARG;PRKAG2;SLC2A4;SREBF1;ADIPOR1;ADIPOR2;IRS1;MTOR","hsa04152"]
["hsa04210","Apoptosis","Cellular Processes","Cell growth and death",21,83,135,7820,{"v":1.94607909189797e-19,"d":"1.95E-19"},{"v":1.06547830281414e-17,"d":"1.07E-17"},14.6559571619813,"RELA;AKT1;BCL2;BCL2L1;BAX;CASP9;MAPK3;MAPK1;CASP3;MAPK8;NFKBIA;BIRC5;BCL2A1;DDIT3;NTRK1;CFLAR;EIF2S1;BCL2L11;TNFSF10;TNFRSF10A;TRAF2","hsa04210"]
["hsa04211","Longevity regulating pathway","Organismal Systems","Aging",11,83,89,7820,{"v":1.82502475729705e-09,"d":"1.83E-09"},{"v":9.08364595109214e-09,"d":"9.08E-09"},11.6447813726817,"RELA;AKT1;BAX;CAT;FOXO1;PPARG;PRKAG2;ADIPOR1;ADIPOR2;IRS1;MTOR","hsa04211"]
["hsa04213","Longevity regulating pathway - multiple species","Organismal Systems","Aging",6,83,62,7820,{"v":4.55612841514272e-05,"d":"4.56E-05"},0.000105030749780659,9.11776136805286,"AKT1;CAT;FOXO1;PRKAG2;IRS1;MTOR","hsa04213"]
["hsa04215","Apoptosis - multiple species","Cellular Processes","Cell growth and death",8,83,32,7820,{"v":9.77243494538004e-10,"d":"9.77E-10"},{"v":5.30471494217196e-09,"d":"5.30E-09"},23.5542168674699,"BCL2;BCL2L1;BAX;CASP9;CASP3;MAPK8;BIRC5;BCL2L11","hsa04215"]
["hsa04217","Necroptosis","Cellular Processes","Cell growth and death",12,83,159,7820,{"v":9.17405872653018e-08,"d":"9.17E-08"},{"v":2.91176646537697e-07,"d":"2.91E-07"},7.11070697885883,"STAT3;BCL2;BAX;MAPK8;STAT1;IL1B;IL1A;JAK1;CFLAR;TNFSF10;TNFRSF10A;TRAF2","hsa04217"]
["hsa04218","Cellular senescence","Cellular Processes","Cell growth and death",14,83,156,7820,{"v":7.10368978605172e-10,"d":"7.10E-10"},{"v":3.98920461282924e-09,"d":"3.99E-09"},8.45535990114303,"RELA;AKT1;CCND1;CDKN1A;MAPK3;MAPK1;IL6;FOXO1;MYC;CXCL8;CCNB1;IL1A;CCNE1;MTOR","hsa04218"]
["hsa04261","Adrenergic signaling in cardiomyocytes","Organismal Systems","Circulatory system",5,83,150,7820,0.021312659735669,0.0313253186718893,3.14056224899598,"AKT1;BCL2;MAPK3;MAPK1;AGTR1","hsa04261"]
["hsa04270","Vascular smooth muscle contraction","Organismal Systems","Circulatory system",6,83,133,7820,0.00279553494015351,0.00497741586905382,4.25038499864118,"MAPK3;MAPK1;EDN1;PRKCD;PRKCB;AGTR1","hsa04270"]
["hsa04310","Wnt signaling pathway","Environmental Information Processing","Signal transduction",5,83,160,7820,0.0272453019314901,0.0389981772744859,2.94427710843373,"CCND1;MAPK8;CTNNB1;MYC;PRKCB","hsa04310"]
["hsa04340","Hedgehog signaling pathway","Environmental Information Processing","Signal transduction",2,83,50,7820,0.0983785941193848,0.125993638082721,3.76867469879518,"CCND1;BCL2","hsa04340"]
["hsa04350","TGF-beta signaling pathway","Environmental Information Processing","Signal transduction",3,83,94,7820,0.0777696985481947,0.102599783024426,3.0069213022302,"MAPK3;MAPK1;MYC","hsa04350"]
["hsa04360","Axon guidance","Organismal Systems","Development and regeneration",3,83,182,7820,0.30447967280614,0.345497659816293,1.55302528796505,"MAPK3;MAPK1;CDC42","hsa04360"]
["hsa04370","VEGF signaling pathway","Environmental Information Processing","Signal transduction",9,83,59,7820,{"v":8.97040299389632e-09,"d":"8.97E-09"},{"v":3.38710044079878e-08,"d":"3.39E-08"},14.3720645293037,"PTGS2;AKT1;VEGFA;CASP9;MAPK3;MAPK1;PRKCB;NOS3;CDC42","hsa04370"]
["hsa04371","Apelin signaling pathway","Environmental Information Processing","Signal transduction",9,83,137,7820,{"v":1.30960969722579e-05,"d":"1.31E-05"},{"v":3.08391960959621e-05,"d":"3.08E-05"},6.1894292498461,"AKT1;CCND1;MAPK3;MAPK1;NOS3;PLAT;PRKAG2;AGTR1;MTOR","hsa04371"]
["hsa04380","Osteoclast differentiation","Organismal Systems","Development and regeneration",12,83,127,7820,{"v":7.26977211231923e-09,"d":"7.27E-09"},{"v":2.94829646777391e-08,"d":"2.95E-08"},8.90238117825633,"RELA;AKT1;MAPK3;MAPK1;MAPK8;NFKBIA;STAT1;PPARG;IL1B;IL1A;JAK1;TRAF2","hsa04380"]
["hsa04390","Hippo signaling pathway","Environmental Information Processing","Signal transduction",4,83,157,7820,0.0851969045730246,0.111060250604121,2.40042974445553,"CCND1;CTNNB1;MYC;BIRC5","hsa04390"]
["hsa04510","Focal adhesion","Cellular Processes","Cellular community - eukaryotes",11,83,201,7820,{"v":7.87100264032418e-06,"d":"7.87E-06"},{"v":1.89423030574835e-05,"d":"1.89E-05"},5.15614697596356,"AKT1;VEGFA;CCND1;BCL2;MAPK3;MAPK1;MAPK8;CTNNB1;PRKCB;HGF;CDC42","hsa04510"]
["hsa04514","Cell adhesion molecules","Environmental Information Processing","Signaling molecules and interaction",5,83,149,7820,0.0207707532528764,0.0307351010971617,3.16163984798253,"SELE;VCAM1;PECAM1;CD80;CD28","hsa04514"]
["hsa04520","Adherens junction","Cellular Processes","Cellular community - eukaryotes",5,83,71,7820,0.000897281015341587,0.00170873515095485,6.63499066689292,"MAPK3;MAPK1;CTNNB1;PTPN1;CDC42","hsa04520"]
["hsa04530","Tight junction","Cellular Processes","Cellular community - eukaryotes",4,83,169,7820,0.104534378813368,0.132329647168368,2.22998502887289,"CCND1;MAPK8;PRKAG2;CDC42","hsa04530"]
["hsa04540","Gap junction","Cellular Processes","Cellular community - eukaryotes",3,83,88,7820,0.0665538750323994,0.0894190100128557,3.21193866374589,"MAPK3;MAPK1;PRKCB","hsa04540"]
["hsa04550","Signaling pathways regulating pluripotency of stem cells","Cellular Processes","Cellular community - eukaryotes",7,83,143,7820,0.000768919692681706,0.00149020719201145,4.61201449153256,"STAT3;AKT1;MAPK3;MAPK1;CTNNB1;MYC;JAK1","hsa04550"]
["hsa04610","Complement and coagulation cascades","Organismal Systems","Immune system",2,83,85,7820,0.227895329521129,0.266893460776081,2.21686746987952,"PLAU;PLAT","hsa04610"]
["hsa04611","Platelet activation","Organismal Systems","Immune system",5,83,124,7820,0.0100302831738495,0.0154692395427679,3.79906723668869,"PTGS1;AKT1;MAPK3;MAPK1;NOS3","hsa04611"]
["hsa04614","Renin-angiotensin system","Organismal Systems","Endocrine system",1,83,23,7820,0.217898021210908,0.256557347554779,4.09638554216868,"AGTR1","hsa04614"]
["hsa04620","Toll-like receptor signaling pathway","Organismal Systems","Immune system",11,83,104,7820,{"v":9.80802809607189e-09,"d":"9.81E-09"},{"v":3.64060703905041e-08,"d":"3.64E-08"},9.96524559777572,"RELA;AKT1;MAPK3;MAPK1;IL6;MAPK8;NFKBIA;STAT1;IL1B;CXCL8;CD80","hsa04620"]
["hsa04621","NOD-like receptor signaling pathway","Organismal Systems","Immune system",14,83,180,7820,{"v":4.67578294904092e-09,"d":"4.68E-09"},{"v":2.00783620752934e-08,"d":"2.01E-08"},7.32797858099063,"RELA;BCL2;BCL2L1;MAPK3;MAPK1;IL6;MAPK8;NFKBIA;STAT1;IL1B;PRKCD;CXCL8;JAK1;TRAF2","hsa04621"]
["hsa04622","RIG-I-like receptor signaling pathway","Organismal Systems","Immune system",5,83,70,7820,0.000841020281398842,0.00161564422479251,6.72977624784854,"RELA;MAPK8;NFKBIA;CXCL8;TRAF2","hsa04622"]
["hsa04623","Cytosolic DNA-sensing pathway","Organismal Systems","Immune system",4,83,63,7820,0.00436963163876684,0.0073049567090835,5.98202333142092,"RELA;IL6;NFKBIA;IL1B","hsa04623"]
["hsa04625","C-type lectin receptor signaling pathway","Organismal Systems","Immune system",12,83,104,7820,{"v":7.10406300914797e-10,"d":"7.10E-10"},{"v":3.98920461282924e-09,"d":"3.99E-09"},10.8711770157553,"PTGS2;RELA;AKT1;MAPK3;MAPK1;IL10;IL6;MAPK8;NFKBIA;STAT1;IL1B;PRKCD","hsa04625"]
["hsa04630","JAK-STAT signaling pathway","Environmental Information Processing","Signal transduction",12,83,162,7820,{"v":1.1282281802433e-07,"d":"1.13E-07"},{"v":3.48002776722934e-07,"d":"3.48E-07"},6.97902721999107,"STAT3;AKT1;CCND1;BCL2;BCL2L1;CDKN1A;IL10;IL6;STAT1;MYC;JAK1;MTOR","hsa04630"]
["hsa04640","Hematopoietic cell lineage","Organismal Systems","Immune system",3,83,99,7820,0.0877084724153696,0.113657724609266,2.85505658999635,"IL6;IL1B;IL1A","hsa04640"]
["hsa04650","Natural killer cell mediated cytotoxicity","Organismal Systems","Immune system",6,83,132,7820,0.00269189878326315,0.0048321789633986,4.28258488499452,"MAPK3;MAPK1;CASP3;PRKCB;TNFSF10;TNFRSF10A","hsa04650"]
["hsa04657","IL-17 signaling pathway","Organismal Systems","Immune system",12,83,94,7820,{"v":2.13620086629923e-10,"d":"2.14E-10"},{"v":1.37596467564568e-09,"d":"1.38E-09"},12.0276852089208,"PTGS2;RELA;MMP9;MAPK3;MAPK1;IL6;CASP3;MAPK8;NFKBIA;IL1B;CXCL8;TRAF2","hsa04657"]
["hsa04658","Th1 and Th2 cell differentiation","Organismal Systems","Immune system",7,83,92,7820,{"v":4.97491236412079e-05,"d":"4.97E-05"},0.000113490188306506,7.16867469879518,"RELA;MAPK3;MAPK1;MAPK8;NFKBIA;STAT1;JAK1","hsa04658"]
["hsa04659","Th17 cell differentiation","Organismal Systems","Immune system",12,83,107,7820,{"v":9.93120148991097e-10,"d":"9.93E-10"},{"v":5.30471494217196e-09,"d":"5.30E-09"},10.5663776601734,"RELA;STAT3;MAPK3;MAPK1;IL6;MAPK8;NFKBIA;STAT1;IL1B;AHR;JAK1;MTOR","hsa04659"]
["hsa04660","T cell receptor signaling pathway","Organismal Systems","Immune system",9,83,104,7820,{"v":1.33327645054303e-06,"d":"1.33E-06"},{"v":3.47604217463003e-06,"d":"3.48E-06"},8.1533827618165,"RELA;AKT1;MAPK3;MAPK1;IL10;MAPK8;NFKBIA;CDC42;CD28","hsa04660"]
["hsa04662","B cell receptor signaling pathway","Organismal Systems","Immune system",6,83,82,7820,0.000219215502580264,0.000452907500613941,6.8939171319424,"RELA;AKT1;MAPK3;MAPK1;NFKBIA;PRKCB","hsa04662"]
["hsa04664","Fc epsilon RI signaling pathway","Organismal Systems","Immune system",4,83,68,7820,0.00574010419362825,0.00931172458077472,5.5421686746988,"AKT1;MAPK3;MAPK1;MAPK8","hsa04664"]
["hsa04666","Fc gamma R-mediated phagocytosis","Organismal Systems","Immune system",6,83,97,7820,0.000545196354049541,0.00109539450951238,5.82784747236368,"AKT1;MAPK3;MAPK1;PRKCD;PRKCB;CDC42","hsa04666"]
["hsa04668","TNF signaling pathway","Environmental Information Processing","Signal transduction",16,83,112,7820,{"v":2.44478874459298e-14,"d":"2.44E-14"},{"v":3.14946314744625e-13,"d":"3.15E-13"},13.4595524956971,"PTGS2;RELA;AKT1;MMP9;MAPK3;MAPK1;IL6;CASP3;MAPK8;NFKBIA;EDN1;IL1B;SELE;VCAM1;CFLAR;TRAF2","hsa04668"]
["hsa04670","Leukocyte transendothelial migration","Organismal Systems","Immune system",7,83,114,7820,0.000193731465139877,0.000411914474423621,5.7852462481505,"MMP2;MMP9;CTNNB1;VCAM1;PRKCB;PECAM1;CDC42","hsa04670"]
["hsa04672","Intestinal immune network for IgA production","Organismal Systems","Immune system",4,83,49,7820,0.00173877108174307,0.00319992325127506,7.69117285468404,"IL10;IL6;CD80;CD28","hsa04672"]
["hsa04710","Circadian rhythm","Organismal Systems","Environmental adaptation",1,83,31,7820,0.282100922081328,0.323456031077543,3.03925378935095,"PRKAG2","hsa04710"]
["hsa04713","Circadian entrainment","Organismal Systems","Environmental adaptation",3,83,97,7820,0.0836702697352603,0.109723287856419,2.91392373618184,"MAPK3;MAPK1;PRKCB","hsa04713"]
["hsa04714","Thermogenesis","Organismal Systems","Environmental adaptation",3,83,218,7820,0.409195878271391,0.457213761946095,1.29656239637449,"PPARG;PRKAG2;MTOR","hsa04714"]
["hsa04720","Long-term potentiation","Organismal Systems","Nervous system",3,83,67,7820,0.0339703178107178,0.0479967716164335,4.21866570760655,"MAPK3;MAPK1;PRKCB","hsa04720"]
["hsa04722","Neurotrophin signaling pathway","Organismal Systems","Nervous system",12,83,119,7820,{"v":3.43356791290394e-09,"d":"3.43E-09"},{"v":1.67100305094658e-08,"d":"1.67E-08"},9.50086058519793,"RELA;AKT1;BCL2;BAX;MAPK3;MAPK1;MAPK8;NFKBIA;PRKCD;NTRK1;IRS1;CDC42","hsa04722"]
["hsa04723","Retrograde endocannabinoid signaling","Organismal Systems","Nervous system",5,83,141,7820,0.0167593973944651,0.0253124691681921,3.34102366914466,"PTGS2;MAPK3;MAPK1;MAPK8;PRKCB","hsa04723"]
["hsa04724","Glutamatergic synapse","Organismal Systems","Nervous system",3,83,114,7820,0.120466310587577,0.150754982963882,2.47939124920736,"MAPK3;MAPK1;PRKCB","hsa04724"]
["hsa04725","Cholinergic synapse","Organismal Systems","Nervous system",5,83,113,7820,0.00684335324913178,0.0109393749018968,4.16888794114511,"AKT1;BCL2;MAPK3;MAPK1;PRKCB","hsa04725"]
["hsa04726","Serotonergic synapse","Organismal Systems","Nervous system",6,83,114,7820,0.00127536240399137,0.00238721680747103,4.95878249841471,"PTGS1;PTGS2;MAPK3;MAPK1;CASP3;PRKCB","hsa04726"]
["hsa04727","GABAergic synapse","Organismal Systems","Nervous system",1,83,89,7820,0.615222924248119,0.647758751972779,1.05861648842561,"PRKCB","hsa04727"]
["hsa04728","Dopaminergic synapse","Organismal Systems","Nervous system",3,83,132,7820,0.164702424193655,0.202639499429272,2.14129244249726,"AKT1;MAPK8;PRKCB","hsa04728"]
["hsa04730","Long-term depression","Organismal Systems","Nervous system",3,83,60,7820,0.0255736084842957,0.0373374683870717,4.71084337349398,"MAPK3;MAPK1;PRKCB","hsa04730"]
["hsa04750","Inflammatory mediator regulation of TRP channels","Organismal Systems","Sensory system",5,83,98,7820,0.00374541718498693,0.00646540593358384,4.80698303417753,"MAPK8;IL1B;PRKCD;PRKCB;NTRK1","hsa04750"]
["hsa04810","Regulation of actin cytoskeleton","Cellular Processes","Cell motility",3,83,218,7820,0.409195878271391,0.457213761946095,1.29656239637449,"MAPK3;MAPK1;CDC42","hsa04810"]
["hsa04910","Insulin signaling pathway","Organismal Systems","Endocrine system",11,83,137,7820,{"v":1.75636231209606e-07,"d":"1.76E-07"},{"v":5.19788305877076e-07,"d":"5.20E-07"},7.56485797203412,"AKT1;MAPK3;MAPK1;MAPK8;FOXO1;PTPN1;PRKAG2;SLC2A4;SREBF1;IRS1;MTOR","hsa04910"]
["hsa04911","Insulin secretion","Organismal Systems","Endocrine system",1,83,86,7820,0.602562433520575,0.637493589086985,1.09554497057999,"PRKCB","hsa04911"]
["hsa04912","GnRH signaling pathway","Organismal Systems","Endocrine system",7,83,93,7820,{"v":5.33418971323744e-05,"d":"5.33E-05"},0.000119202810938673,7.09159217515222,"MMP2;MAPK3;MAPK1;MAPK8;PRKCD;PRKCB;CDC42","hsa04912"]
["hsa04913","Ovarian steroidogenesis","Organismal Systems","Endocrine system",3,83,51,7820,0.0166539772972327,0.0253124691681921,5.54216867469879,"PTGS2;CYP1A1;CYP1B1","hsa04913"]
["hsa04914","Progesterone-mediated oocyte maturation","Organismal Systems","Endocrine system",5,83,100,7820,0.00408446557972693,0.00698826532781404,4.71084337349398,"AKT1;MAPK3;MAPK1;MAPK8;CCNB1","hsa04914"]
["hsa04915","Estrogen signaling pathway","Organismal Systems","Endocrine system",10,83,138,7820,{"v":1.71647786091738e-06,"d":"1.72E-06"},{"v":4.42245472401065e-06,"d":"4.42E-06"},6.82730923694779,"NCOA2;AKT1;BCL2;MMP2;MMP9;MAPK3;MAPK1;PRKCD;NOS3;TGFA","hsa04915"]
["hsa04916","Melanogenesis","Organismal Systems","Endocrine system",5,83,101,7820,0.00426198614684329,0.00717980743198985,4.66420135989503,"MAPK3;MAPK1;EDN1;CTNNB1;PRKCB","hsa04916"]
["hsa04917","Prolactin signaling pathway","Organismal Systems","Endocrine system",8,83,70,7820,{"v":6.3326507913592e-07,"d":"6.33E-07"},{"v":1.712161139886e-06,"d":"1.71E-06"},10.7676419965577,"RELA;STAT3;AKT1;CCND1;MAPK3;MAPK1;MAPK8;STAT1","hsa04917"]
["hsa04918","Thyroid hormone synthesis","Organismal Systems","Endocrine system",1,83,75,7820,0.552519233686453,0.59901837711551,1.25622489959839,"PRKCB","hsa04918"]
["hsa04919","Thyroid hormone signaling pathway","Organismal Systems","Endocrine system",12,83,121,7820,{"v":4.1637920635717e-09,"d":"4.16E-09"},{"v":1.91461787652851e-08,"d":"1.91E-08"},9.34382156726078,"NCOA2;AKT1;CCND1;CASP9;MAPK3;MAPK1;STAT1;FOXO1;CTNNB1;MYC;PRKCB;MTOR","hsa04919"]
["hsa04920","Adipocytokine signaling pathway","Organismal Systems","Endocrine system",13,83,69,7820,{"v":1.96671972415354e-13,"d":"1.97E-13"},{"v":2.15355809794813e-12,"d":"2.15E-12"},17.7510040160643,"RELA;STAT3;AKT1;MAPK8;NFKBIA;PRKAG2;SLC2A4;PPARA;ADIPOR1;ADIPOR2;IRS1;MTOR;TRAF2","hsa04920"]
["hsa04921","Oxytocin signaling pathway","Organismal Systems","Endocrine system",8,83,154,7820,0.000213022227404571,0.000444303502872392,4.89438272570803,"PTGS2;CCND1;CDKN1A;MAPK3;MAPK1;PRKCB;NOS3;PRKAG2","hsa04921"]
["hsa04922","Glucagon signaling pathway","Organismal Systems","Endocrine system",4,83,107,7820,0.0266887882064503,0.0384621323244587,3.52212588672447,"AKT1;FOXO1;PRKAG2;PPARA","hsa04922"]
["hsa04923","Regulation of lipolysis in adipocytes","Organismal Systems","Endocrine system",4,83,57,7820,0.0030402317326122,0.00536944152775865,6.61170999788628,"PTGS1;PTGS2;AKT1;IRS1","hsa04923"]
["hsa04924","Renin secretion","Organismal Systems","Endocrine system",2,83,69,7820,0.166177381014465,0.203311991297028,2.73092369477912,"EDN1;AGTR1","hsa04924"]
["hsa04925","Aldosterone synthesis and secretion","Organismal Systems","Endocrine system",2,83,98,7820,0.279148912254245,0.323456031077543,1.92279321367101,"PRKCB;AGTR1","hsa04925"]
["hsa04926","Relaxin signaling pathway","Organismal Systems","Endocrine system",11,83,129,7820,{"v":9.45013490544395e-08,"d":"9.45E-08"},{"v":2.95654220613175e-07,"d":"2.96E-07"},8.03399645091996,"RELA;AKT1;VEGFA;MMP2;MMP9;MAPK3;MAPK1;MAPK8;NFKBIA;EDN1;NOS3","hsa04926"]
["hsa04927","Cortisol synthesis and secretion","Organismal Systems","Endocrine system",1,83,65,7820,0.501650830205765,0.552067999070666,1.44949026876738,"AGTR1","hsa04927"]
["hsa04928","Parathyroid hormone synthesis, secretion and action","Organismal Systems","Endocrine system",5,83,106,7820,0.00523319480459549,0.00855275867318219,4.44419186178677,"BCL2;CDKN1A;MAPK3;MAPK1;PRKCB","hsa04928"]
["hsa04929","GnRH secretion","Organismal Systems","Endocrine system",4,83,64,7820,0.00462382103515854,0.00767133944469485,5.88855421686747,"AKT1;MAPK3;MAPK1;PRKCB","hsa04929"]
["hsa04930","Type II diabetes mellitus","Human Diseases","Endocrine and metabolic disease",7,83,46,7820,{"v":4.50033205699125e-07,"d":"4.50E-07"},{"v":1.24756040567226e-06,"d":"1.25E-06"},14.3373493975904,"MAPK3;MAPK1;MAPK8;PRKCD;SLC2A4;IRS1;MTOR","hsa04930"]
["hsa04931","Insulin resistance","Human Diseases","Endocrine and metabolic disease",18,83,108,7820,{"v":2.77509497775037e-17,"d":"2.78E-17"},{"v":7.59682250159163e-16,"d":"7.60E-16"},15.7028112449799,"RELA;STAT3;AKT1;IL6;MAPK8;NFKBIA;FOXO1;PRKCD;PRKCB;NOS3;PTPN1;PRKAG2;SLC2A4;PPARA;SREBF1;IRS1;MTOR;NR1H3","hsa04931"]
["hsa04932","Non-alcoholic fatty liver disease","Human Diseases","Endocrine and metabolic disease",21,83,146,7820,{"v":1.0548206514132e-18,"d":"1.05E-18"},{"v":4.62011445318982e-17,"d":"4.62E-17"},13.551741211421,"RELA;AKT1;BAX;IL6;CASP3;MAPK8;IL1B;CXCL8;DDIT3;IL1A;PRKAG2;PPARA;SREBF1;ADIPOR1;ADIPOR2;IRS1;EIF2S1;BCL2L11;TRAF2;CDC42;NR1H3","hsa04932"]
["hsa04933","AGE-RAGE signaling pathway in diabetic complications","Human Diseases","Endocrine and metabolic disease",26,83,100,7820,{"v":2.51077089241341e-30,"d":"2.51E-30"},{"v":5.49858825438536e-28,"d":"5.50E-28"},24.4963855421687,"RELA;STAT3;AKT1;VEGFA;CCND1;BCL2;BAX;MMP2;MAPK3;MAPK1;IL6;CASP3;MAPK8;STAT1;EDN1;FOXO1;IL1B;SELE;VCAM1;PRKCD;CXCL8;PRKCB;NOS3;IL1A;AGTR1;CDC42","hsa04933"]
["hsa04934","Cushing syndrome","Human Diseases","Endocrine and metabolic disease",8,83,155,7820,0.000222700602152818,0.000455807774499693,4.86280606296152,"CCND1;CDKN1A;MAPK3;MAPK1;CTNNB1;AHR;CCNE1;AGTR1","hsa04934"]
["hsa04935","Growth hormone synthesis, secretion and action","Organismal Systems","Endocrine system",9,83,119,7820,{"v":4.12677954560615e-06,"d":"4.13E-06"},{"v":1.02700536419062e-05,"d":"1.03E-05"},7.12564543889845,"STAT3;AKT1;MAPK3;MAPK1;MAPK8;STAT1;PRKCB;IRS1;MTOR","hsa04935"]
["hsa04940","Type I diabetes mellitus","Human Diseases","Endocrine and metabolic disease",4,83,43,7820,0.00106278987015152,0.00200647397899296,8.76435976463996,"IL1B;IL1A;CD80;CD28","hsa04940"]
["hsa04960","Aldosterone-regulated sodium reabsorption","Organismal Systems","Excretory system",4,83,37,7820,0.000596907320023304,0.00117768200977571,10.185607294041,"MAPK3;MAPK1;PRKCB;IRS1","hsa04960"]
["hsa04961","Endocrine and other factor-regulated calcium reabsorption","Organismal Systems","Excretory system",1,83,53,7820,0.433023538866568,0.481381497521718,1.77767674471471,"PRKCB","hsa04961"]
["hsa04970","Salivary secretion","Organismal Systems","Digestive system",1,83,92,7820,0.627484817048407,0.654377023493338,1.02409638554217,"PRKCB","hsa04970"]
["hsa04971","Gastric acid secretion","Organismal Systems","Digestive system",1,83,76,7820,0.557314702195687,0.601240984142146,1.23969562460368,"PRKCB","hsa04971"]
["hsa04972","Pancreatic secretion","Organismal Systems","Digestive system",1,83,101,7820,0.662001023794929,0.680648939958166,0.932840271979005,"PRKCB","hsa04972"]
["hsa04973","Carbohydrate digestion and absorption","Organismal Systems","Digestive system",2,83,47,7820,0.088569395753937,0.114098221588895,4.0092284029736,"AKT1;PRKCB","hsa04973"]
["hsa05010","Alzheimer disease","Human Diseases","Neurodegenerative disease",17,83,355,7820,{"v":1.32060285238834e-07,"d":"1.32E-07"},{"v":4.01683367601452e-07,"d":"4.02E-07"},4.51179365348719,"PTGS2;RELA;AKT1;CASP9;MAPK3;MAPK1;IL6;CASP3;MAPK8;CTNNB1;IL1B;DDIT3;IL1A;IRS1;MTOR;EIF2S1;TRAF2","hsa05010"]
["hsa05012","Parkinson disease","Human Diseases","Neurodegenerative disease",8,83,236,7820,0.0034299119884257,0.00600920580372183,3.19379211762303,"BCL2L1;BAX;CASP9;CASP3;MAPK8;DDIT3;NFE2L2;EIF2S1","hsa05012"]
["hsa05014","Amyotrophic lateral sclerosis","Human Diseases","Neurodegenerative disease",10,83,350,7820,0.00374934499344816,0.00646540593358384,2.69191049913941,"BCL2;BCL2L1;BAX;CASP9;CASP3;CAT;DDIT3;MTOR;EIF2S1;TRAF2","hsa05014"]
["hsa05016","Huntington disease","Human Diseases","Neurodegenerative disease",7,83,293,7820,0.0354616070928254,0.0494655538428584,2.25091492248859,"BAX;CASP9;CASP3;MAPK8;PPARG;MTOR;TRAF2","hsa05016"]
["hsa05017","Spinocerebellar ataxia","Human Diseases","Neurodegenerative disease",5,83,142,7820,0.0172298756935999,0.0258448135403998,3.31749533344646,"AKT1;MAPK8;PRKCB;MTOR;TRAF2","hsa05017"]
["hsa05020","Prion disease","Human Diseases","Neurodegenerative disease",12,83,259,7820,{"v":1.61177297010816e-05,"d":"1.61E-05"},{"v":3.75508808993285e-05,"d":"3.76E-05"},4.36526026887473,"BAX;CASP9;MAPK3;MAPK1;IL6;CASP3;MAPK8;IL1B;PRKCD;DDIT3;IL1A;EIF2S1","hsa05020"]
["hsa05022","Pathways of neurodegeneration - multiple diseases","Human Diseases","Neurodegenerative disease",20,83,461,7820,{"v":4.34803987287716e-08,"d":"4.35E-08"},{"v":1.48784489400015e-07,"d":"1.49E-07"},4.08749967331365,"PTGS2;RELA;BCL2;BCL2L1;BAX;CASP9;MAPK3;MAPK1;IL6;CASP3;MAPK8;CAT;CTNNB1;IL1B;PRKCB;DDIT3;IL1A;MTOR;EIF2S1;TRAF2","hsa05022"]
["hsa05030","Cocaine addiction","Human Diseases","Substance dependence",1,83,49,7820,0.408134824708713,0.457213761946095,1.92279321367101,"RELA","hsa05030"]
["hsa05031","Amphetamine addiction","Human Diseases","Substance dependence",1,83,69,7820,0.522649621902056,0.569454065654479,1.36546184738956,"PRKCB","hsa05031"]
["hsa05032","Morphine addiction","Human Diseases","Substance dependence",1,83,91,7820,0.623441034654347,0.65327074923111,1.0353501919767,"PRKCB","hsa05032"]
["hsa05034","Alcoholism","Human Diseases","Substance dependence",2,83,187,7820,0.594525296250824,0.632043882907429,1.00766703176342,"MAPK3;MAPK1","hsa05034"]
["hsa05100","Bacterial invasion of epithelial cells","Human Diseases","Infectious disease: bacterial",2,83,77,7820,0.196718258684633,0.236710432153487,2.44719136285401,"CTNNB1;CDC42","hsa05100"]
["hsa05120","Epithelial cell signaling in Helicobacter pylori infection","Human Diseases","Infectious disease: bacterial",6,83,70,7820,{"v":9.08282737942112e-05,"d":"9.08E-05"},0.000196944474860715,8.07573149741824,"RELA;CASP3;MAPK8;NFKBIA;CXCL8;CDC42","hsa05120"]
["hsa05130","Pathogenic Escherichia coli infection","Human Diseases","Infectious disease: bacterial",15,83,197,7820,{"v":1.65628936048959e-09,"d":"1.66E-09"},{"v":8.4355202313307e-09,"d":"8.44E-09"},7.17387315760504,"RELA;BAX;CASP9;MAPK3;MAPK1;IL6;CASP3;MAPK8;NFKBIA;IL1B;CXCL8;TNFSF10;TNFRSF10A;TRAF2;CDC42","hsa05130"]
["hsa05131","Shigellosis","Human Diseases","Infectious disease: bacterial",16,83,245,7820,{"v":4.1964227430762e-09,"d":"4.20E-09"},{"v":1.91461787652851e-08,"d":"1.91E-08"},6.15293828374723,"RELA;AKT1;BCL2;BCL2L1;BAX;MAPK3;MAPK1;MAPK8;NFKBIA;FOXO1;IL1B;PRKCD;CXCL8;MTOR;TRAF2;CDC42","hsa05131"]
["hsa05132","Salmonella infection","Human Diseases","Infectious disease: bacterial",18,83,249,7820,{"v":7.21763665564457e-11,"d":"7.22E-11"},{"v":5.64522295566486e-10,"d":"5.65E-10"},6.81085788938888,"RELA;AKT1;BCL2;BAX;MAPK3;MAPK1;IL6;CASP3;MAPK8;NFKBIA;CTNNB1;MYC;IL1B;CXCL8;TNFSF10;TNFRSF10A;TRAF2;CDC42","hsa05132"]
["hsa05133","Pertussis","Human Diseases","Infectious disease: bacterial",10,83,76,7820,{"v":5.6371201684146e-09,"d":"5.64E-09"},{"v":2.32930059789207e-08,"d":"2.33E-08"},12.3969562460368,"RELA;MAPK3;MAPK1;IL10;IL6;CASP3;MAPK8;IL1B;CXCL8;IL1A","hsa05133"]
["hsa05134","Legionellosis","Human Diseases","Infectious disease: bacterial",7,83,57,7820,{"v":2.02369277685532e-06,"d":"2.02E-06"},{"v":5.15335718757344e-06,"d":"5.15E-06"},11.570492496301,"RELA;CASP9;IL6;CASP3;NFKBIA;IL1B;CXCL8","hsa05134"]
["hsa05135","Yersinia infection","Human Diseases","Infectious disease: bacterial",12,83,137,7820,{"v":1.72635819554525e-08,"d":"1.73E-08"},{"v":6.30120741374018e-08,"d":"6.30E-08"},8.25257233312813,"RELA;AKT1;MAPK3;MAPK1;IL10;IL6;MAPK8;NFKBIA;IL1B;CXCL8;TRAF2;CDC42","hsa05135"]
["hsa05140","Leishmaniasis","Human Diseases","Infectious disease: parasitic",11,83,76,7820,{"v":3.19735946969431e-10,"d":"3.20E-10"},{"v":1.94506034406404e-09,"d":"1.95E-09"},13.6366518706405,"PTGS2;RELA;MAPK3;MAPK1;IL10;NFKBIA;STAT1;IL1B;PRKCB;IL1A;JAK1","hsa05140"]
["hsa05142","Chagas disease","Human Diseases","Infectious disease: parasitic",11,83,102,7820,{"v":7.96877082179337e-09,"d":"7.97E-09"},{"v":3.11635858923705e-08,"d":"3.12E-08"},10.1606425702811,"RELA;AKT1;MAPK3;MAPK1;IL10;IL6;MAPK8;NFKBIA;IL1B;CXCL8;CFLAR","hsa05142"]
["hsa05143","African trypanosomiasis","Human Diseases","Infectious disease: parasitic",6,83,37,7820,{"v":2.12855719473752e-06,"d":"2.13E-06"},{"v":5.35809224882203e-06,"d":"5.36E-06"},15.2784109410615,"IL10;IL6;IL1B;SELE;VCAM1;PRKCB","hsa05143"]
["hsa05144","Malaria","Human Diseases","Infectious disease: parasitic",8,83,50,7820,{"v":4.27489634588791e-08,"d":"4.27E-08"},{"v":1.4860353964277e-07,"d":"1.49E-07"},15.0746987951807,"IL10;IL6;IL1B;SELE;VCAM1;CXCL8;PECAM1;HGF","hsa05144"]
["hsa05145","Toxoplasmosis","Human Diseases","Infectious disease: parasitic",14,83,112,7820,{"v":7.75621000296122e-12,"d":"7.76E-12"},{"v":7.07754162770211e-11,"d":"7.08E-11"},11.7771084337349,"RELA;STAT3;AKT1;BCL2;BCL2L1;CASP9;MAPK3;MAPK1;IL10;CASP3;MAPK8;NFKBIA;STAT1;JAK1","hsa05145"]
["hsa05146","Amoebiasis","Human Diseases","Infectious disease: parasitic",7,83,102,7820,{"v":9.63035594984341e-05,"d":"9.63E-05"},0.000206769407158403,6.46586345381526,"RELA;IL10;IL6;CASP3;IL1B;CXCL8;PRKCB","hsa05146"]
["hsa05150","Staphylococcus aureus infection","Human Diseases","Infectious disease: bacterial",1,83,95,7820,0.639360512954788,0.663601669844069,0.991756499682942,"IL10","hsa05150"]
["hsa05152","Tuberculosis","Human Diseases","Infectious disease: bacterial",15,83,179,7820,{"v":4.31972723174938e-10,"d":"4.32E-10"},{"v":2.55681152365707e-09,"d":"2.56E-09"},7.89526822373292,"RELA;AKT1;BCL2;BAX;CASP9;MAPK3;MAPK1;IL10;IL6;CASP3;MAPK8;STAT1;IL1B;IL1A;JAK1","hsa05152"]
["hsa05160","Hepatitis C","Human Diseases","Infectious disease: viral",20,83,157,7820,{"v":9.23892279614394e-17,"d":"9.24E-17"},{"v":2.09575903065124e-15,"d":"2.10E-15"},12.0021487222776,"RELA;STAT3;AKT1;CCND1;CDKN1A;BAX;CASP9;MAPK3;MAPK1;CASP3;NFKBIA;STAT1;CTNNB1;MYC;PPARA;JAK1;CFLAR;EIF2S1;TRAF2;NR1H3","hsa05160"]
["hsa05161","Hepatitis B","Human Diseases","Infectious disease: viral",21,83,161,7820,{"v":8.48714309685203e-18,"d":"8.49E-18"},{"v":3.09780723035099e-16,"d":"3.10E-16"},12.289156626506,"RELA;STAT3;AKT1;BCL2;CDKN1A;BAX;CASP9;MMP9;MAPK3;MAPK1;IL6;CASP3;MAPK8;NFKBIA;STAT1;MYC;CXCL8;PRKCB;BIRC5;CCNE1;JAK1","hsa05161"]
["hsa05162","Measles","Human Diseases","Infectious disease: viral",19,83,139,7820,{"v":1.5613153258624e-16,"d":"1.56E-16"},{"v":3.10843687603514e-15,"d":"3.11E-15"},12.878564618185,"RELA;STAT3;AKT1;CCND1;BCL2;BCL2L1;BAX;CASP9;IL6;CASP3;MAPK8;NFKBIA;STAT1;IL1B;IL1A;CCNE1;JAK1;EIF2S1;CD28","hsa05162"]
["hsa05163","Human cytomegalovirus infection","Human Diseases","Infectious disease: viral",22,83,225,7820,{"v":6.60481954168761e-16,"d":"6.60E-16"},{"v":1.11265806125353e-14,"d":"1.11E-14"},9.21231593038822,"PTGS2;RELA;STAT3;AKT1;VEGFA;CCND1;CDKN1A;BAX;CASP9;MAPK3;MAPK1;IL6;CASP3;NFKBIA;CTNNB1;MYC;IL1B;CXCL8;PRKCB;JAK1;MTOR;TRAF2","hsa05163"]
["hsa05164","Influenza A","Human Diseases","Infectious disease: viral",18,83,171,7820,{"v":1.16161775675958e-13,"d":"1.16E-13"},{"v":1.3389173091071e-12,"d":"1.34E-12"},9.91756499682942,"RELA;AKT1;BAX;CASP9;MAPK3;MAPK1;IL6;CASP3;NFKBIA;STAT1;IL1B;CXCL8;PRKCB;IL1A;JAK1;EIF2S1;TNFSF10;TNFRSF10A","hsa05164"]
["hsa05165","Human papillomavirus infection","Human Diseases","Infectious disease: viral",17,83,331,7820,{"v":4.76077794563539e-08,"d":"4.76E-08"},{"v":1.57971268196084e-07,"d":"1.58E-07"},4.83893277035635,"PTGS2;RELA;AKT1;VEGFA;CCND1;CDKN1A;BAX;MAPK3;MAPK1;CASP3;STAT1;FOXO1;CTNNB1;CCNE1;JAK1;MTOR;CDC42","hsa05165"]
["hsa05166","Human T-cell leukemia virus 1 infection","Human Diseases","Infectious disease: viral",14,83,219,7820,{"v":5.7656102123084e-08,"d":"5.77E-08"},{"v":1.88458005447095e-07,"d":"1.88E-07"},6.0229960939649,"RELA;AKT1;CCND1;BCL2L1;CDKN1A;BAX;MAPK3;MAPK1;IL6;MAPK8;NFKBIA;MYC;CCNE1;JAK1","hsa05166"]
["hsa05167","Kaposi sarcoma-associated herpesvirus infection","Human Diseases","Infectious disease: viral",22,83,193,7820,{"v":2.40527923861569e-17,"d":"2.41E-17"},{"v":7.5250879036691e-16,"d":"7.53E-16"},10.7397465509707,"PTGS2;RELA;STAT3;AKT1;VEGFA;CCND1;CDKN1A;BAX;CASP9;MAPK3;MAPK1;IL6;CASP3;MAPK8;NFKBIA;STAT1;CTNNB1;MYC;CXCL8;JAK1;MTOR;TRAF2","hsa05167"]
["hsa05168","Herpes simplex virus 1 infection","Human Diseases","Infectious disease: viral",15,83,498,7820,0.000201294961510509,0.000423880736257707,2.83785745391203,"RELA;AKT1;BCL2;BCL2L1;BAX;CASP9;IL6;CASP3;NFKBIA;STAT1;IL1B;JAK1;MTOR;EIF2S1;TRAF2","hsa05168"]
["hsa05169","Epstein-Barr virus infection","Human Diseases","Infectious disease: viral",18,83,202,7820,{"v":2.10216590364553e-12,"d":"2.10E-12"},{"v":2.09261060408351e-11,"d":"2.09E-11"},8.39556244781105,"RELA;STAT3;AKT1;CCND1;BCL2;CDKN1A;BAX;CASP9;IL6;CASP3;MAPK8;NFKBIA;STAT1;MYC;CCNE1;JAK1;BCL2L11;TRAF2","hsa05169"]
["hsa05170","Human immunodeficiency virus 1 infection","Human Diseases","Infectious disease: viral",15,83,212,7820,{"v":4.5717252287185e-09,"d":"4.57E-09"},{"v":2.00783620752934e-08,"d":"2.01E-08"},6.66628779268015,"RELA;AKT1;BCL2;BCL2L1;BAX;CASP9;MAPK3;MAPK1;CASP3;MAPK8;NFKBIA;PRKCB;CCNB1;MTOR;TRAF2","hsa05170"]
["hsa05171","Coronavirus disease - COVID-19","Human Diseases","Infectious disease: viral",13,83,232,7820,{"v":8.26350410201581e-07,"d":"8.26E-07"},{"v":2.18037035944754e-06,"d":"2.18E-06"},5.27939343581221,"RELA;STAT3;MAPK3;MAPK1;IL6;MAPK8;NFKBIA;STAT1;IL1B;CXCL8;PRKCB;JAK1;AGTR1","hsa05171"]
["hsa05200","Pathways in cancer","Human Diseases","Cancer: overview",41,83,529,7820,{"v":1.45861178797506e-26,"d":"1.46E-26"},{"v":1.5971799078327e-24,"d":"1.60E-24"},7.30225248821372,"PTGS2;RELA;STAT3;AKT1;VEGFA;CCND1;BCL2;BCL2L1;CDKN1A;BAX;CASP9;MMP2;MMP9;MAPK3;MAPK1;IL6;CASP3;MAPK8;NFKBIA;STAT1;RUNX1T1;EDN1;FOXO1;PPARG;CTNNB1;MYC;CXCL8;PRKCB;BIRC5;HGF;NFE2L2;CCNE1;NTRK1;JAK1;AGTR1;MTOR;BCL2L11;TRAF2;CDC42;BRCA2;TGFA","hsa05200"]
["hsa05202","Transcriptional misregulation in cancer","Human Diseases","Cancer: overview",17,83,192,7820,{"v":1.03947640129366e-11,"d":"1.04E-11"},{"v":9.10581327533242e-11,"d":"9.11E-11"},8.34211847389558,"RELA;BCL2L1;CDKN1A;BAX;PLAU;MMP9;IL6;RUNX1T1;FOXO1;PPARG;MYC;CXCL8;BCL2A1;DDIT3;PLAT;MPO;NTRK1","hsa05202"]
["hsa05203","Viral carcinogenesis","Human Diseases","Cancer: overview",13,83,204,7820,{"v":1.87639364677751e-07,"d":"1.88E-07"},{"v":5.47906944859031e-07,"d":"5.48E-07"},6.00401606425703,"RELA;STAT3;CCND1;CDKN1A;BAX;MAPK3;MAPK1;CASP3;NFKBIA;CCNE1;JAK1;TRAF2;CDC42","hsa05203"]
["hsa05204","Chemical carcinogenesis","Human Diseases","Cancer: overview",3,83,82,7820,0.0561545200289506,0.0763840986729204,3.4469585659712,"PTGS2;CYP1A1;CYP1B1","hsa05204"]
["hsa05205","Proteoglycans in cancer","Human Diseases","Cancer: overview",17,83,202,7820,{"v":2.35706604864873e-11,"d":"2.36E-11"},{"v":1.98537486405412e-10,"d":"1.99E-10"},7.92914231182154,"STAT3;AKT1;VEGFA;CCND1;CDKN1A;PLAU;MMP2;MMP9;MAPK3;MAPK1;CASP3;CTNNB1;MYC;PRKCB;HGF;MTOR;CDC42","hsa05205"]
["hsa05206","MicroRNAs in cancer","Human Diseases","Cancer: overview",19,83,161,7820,{"v":2.56924550005691e-15,"d":"2.57E-15"},{"v":3.75109843008308e-14,"d":"3.75E-14"},11.118760757315,"PTGS2;STAT3;VEGFA;CCND1;BCL2;CDKN1A;PLAU;MMP9;MAPK3;MAPK1;CASP3;MYC;BRCA1;PRKCB;CYP1B1;CCNE1;IRS1;MTOR;BCL2L11","hsa05206"]
["hsa05210","Colorectal cancer","Human Diseases","Cancer: specific types",16,83,86,7820,{"v":3.07156247691572e-16,"d":"3.07E-16"},{"v":5.60560152037119e-15,"d":"5.61E-15"},17.5287195292799,"AKT1;CCND1;BCL2;CDKN1A;BAX;CASP9;MAPK3;MAPK1;CASP3;MAPK8;CTNNB1;MYC;BIRC5;MTOR;BCL2L11;TGFA","hsa05210"]
["hsa05211","Renal cell carcinoma","Human Diseases","Cancer: specific types",8,83,69,7820,{"v":5.65720184967426e-07,"d":"5.66E-07"},{"v":1.54865900634833e-06,"d":"1.55E-06"},10.9236947791165,"AKT1;VEGFA;CDKN1A;MAPK3;MAPK1;HGF;CDC42;TGFA","hsa05211"]
["hsa05212","Pancreatic cancer","Human Diseases","Cancer: specific types",18,83,76,7820,{"v":3.22330435448665e-20,"d":"3.22E-20"},{"v":2.35301217877525e-18,"d":"2.35E-18"},22.3145212428662,"RELA;STAT3;AKT1;VEGFA;CCND1;BCL2L1;CDKN1A;BAX;CASP9;MAPK3;MAPK1;MAPK8;STAT1;JAK1;MTOR;CDC42;BRCA2;TGFA","hsa05212"]
["hsa05213","Endometrial cancer","Human Diseases","Cancer: specific types",9,83,58,7820,{"v":7.66749601587204e-09,"d":"7.67E-09"},{"v":3.05305750450177e-08,"d":"3.05E-08"},14.6198587453261,"AKT1;CCND1;CDKN1A;BAX;CASP9;MAPK3;MAPK1;CTNNB1;MYC","hsa05213"]
["hsa05214","Glioma","Human Diseases","Cancer: specific types",9,83,75,7820,{"v":7.81649550949895e-08,"d":"7.82E-08"},{"v":2.51737134791216e-07,"d":"2.52E-07"},11.3060240963855,"AKT1;CCND1;CDKN1A;BAX;MAPK3;MAPK1;PRKCB;MTOR;TGFA","hsa05214"]
["hsa05215","Prostate cancer","Human Diseases","Cancer: specific types",17,83,97,7820,{"v":9.56967593904676e-17,"d":"9.57E-17"},{"v":2.09575903065124e-15,"d":"2.10E-15"},16.5122345050304,"RELA;AKT1;CCND1;BCL2;CDKN1A;CASP9;PLAU;MMP9;MAPK3;MAPK1;NFKBIA;FOXO1;CTNNB1;PLAT;CCNE1;MTOR;TGFA","hsa05215"]
["hsa05216","Thyroid cancer","Human Diseases","Cancer: specific types",9,83,37,7820,{"v":1.07240434961153e-10,"d":"1.07E-10"},{"v":7.57601782467502e-10,"d":"7.58E-10"},22.9176164115923,"CCND1;CDKN1A;BAX;MAPK3;MAPK1;PPARG;CTNNB1;MYC;NTRK1","hsa05216"]
["hsa05217","Basal cell carcinoma","Human Diseases","Cancer: specific types",3,83,63,7820,0.0290164709863969,0.0412636827663697,4.48651749856569,"CDKN1A;BAX;CTNNB1","hsa05217"]
["hsa05218","Melanoma","Human Diseases","Cancer: specific types",7,83,72,7820,{"v":9.92095003744027e-06,"d":"9.92E-06"},{"v":2.36161745456459e-05,"d":"2.36E-05"},9.15997322623829,"AKT1;CCND1;CDKN1A;BAX;MAPK3;MAPK1;HGF","hsa05218"]
["hsa05219","Bladder cancer","Human Diseases","Cancer: specific types",9,83,41,7820,{"v":2.91831504934375e-10,"d":"2.92E-10"},{"v":1.82603141658937e-09,"d":"1.83E-09"},20.6817513958272,"VEGFA;CCND1;CDKN1A;MMP2;MMP9;MAPK3;MAPK1;MYC;CXCL8","hsa05219"]
["hsa05220","Chronic myeloid leukemia","Human Diseases","Cancer: specific types",10,83,76,7820,{"v":5.6371201684146e-09,"d":"5.64E-09"},{"v":2.32930059789207e-08,"d":"2.33E-08"},12.3969562460368,"RELA;AKT1;CCND1;BCL2L1;CDKN1A;BAX;MAPK3;MAPK1;NFKBIA;MYC","hsa05220"]
["hsa05221","Acute myeloid leukemia","Human Diseases","Cancer: specific types",11,83,67,7820,{"v":7.74576520696451e-11,"d":"7.75E-11"},{"v":5.84938820801803e-10,"d":"5.85E-10"},15.4684409278907,"RELA;STAT3;AKT1;CCND1;MAPK3;MAPK1;RUNX1T1;MYC;BCL2A1;MPO;MTOR","hsa05221"]
["hsa05222","Small cell lung cancer","Human Diseases","Cancer: specific types",14,83,92,7820,{"v":4.80601677081135e-13,"d":"4.81E-13"},{"v":5.01198891813184e-12,"d":"5.01E-12"},14.3373493975904,"PTGS2;RELA;AKT1;CCND1;BCL2;BCL2L1;CDKN1A;BAX;CASP9;CASP3;NFKBIA;MYC;CCNE1;TRAF2","hsa05222"]
["hsa05223","Non-small cell lung cancer","Human Diseases","Cancer: specific types",11,83,72,7820,{"v":1.74575824995875e-10,"d":"1.75E-10"},{"v":1.15854865679081e-09,"d":"1.16E-09"},14.3942436412316,"STAT3;AKT1;CCND1;CDKN1A;BAX;CASP9;MAPK3;MAPK1;PRKCB;HGF;TGFA","hsa05223"]
["hsa05224","Breast cancer","Human Diseases","Cancer: specific types",11,83,147,7820,{"v":3.60198283795437e-07,"d":"3.60E-07"},{"v":1.0244600539117e-06,"d":"1.02E-06"},7.05024178346037,"AKT1;CCND1;CDKN1A;BAX;MAPK3;MAPK1;CTNNB1;MYC;BRCA1;MTOR;BRCA2","hsa05224"]
["hsa05225","Hepatocellular carcinoma","Human Diseases","Cancer: specific types",14,83,166,7820,{"v":1.61816237516712e-09,"d":"1.62E-09"},{"v":8.4355202313307e-09,"d":"8.44E-09"},7.94600087095369,"AKT1;CCND1;BCL2L1;CDKN1A;BAX;MAPK3;MAPK1;CTNNB1;MYC;PRKCB;HGF;NFE2L2;MTOR;TGFA","hsa05225"]
["hsa05226","Gastric cancer","Human Diseases","Cancer: specific types",12,83,148,7820,{"v":4.12534840163761e-08,"d":"4.13E-08"},{"v":1.45717951606232e-07,"d":"1.46E-07"},7.63920547053077,"AKT1;CCND1;BCL2;CDKN1A;BAX;MAPK3;MAPK1;CTNNB1;MYC;HGF;CCNE1;MTOR","hsa05226"]
["hsa05230","Central carbon metabolism in cancer","Human Diseases","Cancer: overview",6,83,70,7820,{"v":9.08282737942112e-05,"d":"9.08E-05"},0.000196944474860715,8.07573149741824,"AKT1;MAPK3;MAPK1;MYC;NTRK1;MTOR","hsa05230"]
["hsa05231","Choline metabolism in cancer","Human Diseases","Cancer: overview",6,83,98,7820,0.000575884399888629,0.001146533487051,5.76837964101303,"AKT1;MAPK3;MAPK1;MAPK8;PRKCB;MTOR","hsa05231"]
["hsa05235","PD-L1 expression and PD-1 checkpoint pathway in cancer","Human Diseases","Cancer: overview",10,83,89,7820,{"v":2.68680670873333e-08,"d":"2.69E-08"},{"v":9.64607654446884e-08,"d":"9.65E-08"},10.5861648842561,"RELA;STAT3;AKT1;MAPK3;MAPK1;NFKBIA;STAT1;JAK1;MTOR;CD28","hsa05235"]
["hsa05310","Asthma","Human Diseases","Immune disease",1,83,31,7820,0.282100922081328,0.323456031077543,3.03925378935095,"IL10","hsa05310"]
["hsa05320","Autoimmune thyroid disease","Human Diseases","Immune disease",3,83,53,7820,0.0184536389869243,0.0274921560417444,5.33303023414412,"IL10;CD80;CD28","hsa05320"]
["hsa05321","Inflammatory bowel disease","Human Diseases","Immune disease",7,83,65,7820,{"v":4.97718159837437e-06,"d":"4.98E-06"},{"v":1.22472221353257e-05,"d":"1.22E-05"},10.1464318813716,"RELA;STAT3;IL10;IL6;STAT1;IL1B;IL1A","hsa05321"]
["hsa05322","Systemic lupus erythematosus","Human Diseases","Immune disease",3,83,136,7820,0.175129479773844,0.213074200391511,2.07831325301205,"IL10;CD80;CD28","hsa05322"]
["hsa05323","Rheumatoid arthritis","Human Diseases","Immune disease",7,83,93,7820,{"v":5.33418971323744e-05,"d":"5.33E-05"},0.000119202810938673,7.09159217515222,"VEGFA;IL6;IL1B;CXCL8;IL1A;CD80;CD28","hsa05323"]
["hsa05330","Allograft rejection","Human Diseases","Immune disease",3,83,38,7820,0.00744372274677938,0.0118128643590195,7.43817374762207,"IL10;CD80;CD28","hsa05330"]
["hsa05332","Graft-versus-host disease","Human Diseases","Immune disease",5,83,42,7820,{"v":7.45584684166521e-05,"d":"7.46E-05"},0.000164932369527745,11.2162937464142,"IL6;IL1B;IL1A;CD80;CD28","hsa05332"]
["hsa05410","Hypertrophic cardiomyopathy","Human Diseases","Cardiovascular disease",3,83,90,7820,0.0702038397783962,0.0931796418876896,3.14056224899598,"IL6;EDN1;PRKAG2","hsa05410"]
["hsa05412","Arrhythmogenic right ventricular cardiomyopathy","Human Diseases","Cardiovascular disease",1,83,77,7820,0.562059392241886,0.603387288730259,1.22359568142701,"CTNNB1","hsa05412"]
["hsa05416","Viral myocarditis","Human Diseases","Cardiovascular disease",5,83,60,7820,0.00041227082723964,0.000835993621902604,7.85140562248996,"CCND1;CASP9;CASP3;CD80;CD28","hsa05416"]
["hsa05418","Fluid shear stress and atherosclerosis","Human Diseases","Cardiovascular disease",17,83,137,7820,{"v":3.85931776318508e-14,"d":"3.86E-14"},{"v":4.69550327854185e-13,"d":"4.70E-13"},11.6911441385982,"RELA;AKT1;VEGFA;BCL2;MMP2;MMP9;MAPK8;EDN1;CTNNB1;IL1B;SELE;VCAM1;PECAM1;NOS3;PLAT;IL1A;NFE2L2","hsa05418"]

{"sheet":"S6(Reactome)","index":5,"n_rows":792,"n_cols":10,"rows_kept":792,"flags":["formulas_cached_only"]}
["id","Pathway","ListHits","ListTotal","PopHits","PopTotal","Enrichment_score","p-value","q-value","geneID"]
["R-HSA-6785807","Interleukin-4 and Interleukin-13 signaling",22,87,108,11092,25.9710515112814,{"v":7.98567589876076e-26,"d":"7.99E-26"},{"v":6.31666963591976e-23,"d":"6.32E-23"},"PTGS2;STAT3;AKT1;VEGFA;CCND1;BCL2;BCL2L1;CDKN1A;MMP2;MMP9;IL10;IL6;STAT1;FOXO1;MYC;IL1B;VCAM1;CXCL8;BIRC5;HGF;IL1A;JAK1"]
["R-HSA-449147","Signaling by Interleukins",32,87,462,11092,8.83077076180524,{"v":1.78319318778016e-22,"d":"1.78E-22"},{"v":7.05252905767054e-20,"d":"7.05E-20"},"PTGS2;RELA;STAT3;AKT1;VEGFA;CCND1;BCL2;BCL2L1;CDKN1A;MMP2;MMP9;MAPK3;MAPK1;IL10;IL6;CASP3;MAPK8;NFKBIA;STAT1;FOXO1;MYC;IL1B;VCAM1;CXCL8;BIRC5;HGF;IL1A;CD80;JAK1;IRS1;CCR2;CDC42"]
["R-HSA-1280215","Cytokine Signaling in Immune system",36,87,715,11092,6.41929105377381,{"v":9.26341031928895e-21,"d":"9.26E-21"},{"v":2.44245252085252e-18,"d":"2.44E-18"},"PTGS2;RELA;STAT3;AKT1;VEGFA;CCND1;BCL2;BCL2L1;CDKN1A;MMP2;MMP9;MAPK3;MAPK1;IL10;IL6;CASP3;MAPK8;NFKBIA;STAT1;FOXO1;MYC;IL1B;VCAM1;PRKCD;CXCL8;BIRC5;PTPN1;HGF;IL1A;CD80;JAK1;IRS1;CCR2;BCL2L11;TRAF2;CDC42"]
["R-HSA-168256","Immune System",49,87,2018,11092,3.0957474681886,{"v":1.50906652657219e-15,"d":"1.51E-15"},{"v":2.98417905629651e-13,"d":"2.98E-13"},"PTGS2;RELA;STAT3;AKT1;VEGFA;CCND1;BCL2;BCL2L1;CDKN1A;CASP9;PLAU;MMP2;MMP9;MAPK3;MAPK1;IL10;IL6;CASP3;MAPK8;NFKBIA;XDH;CAT;STAT1;FOXO1;CTNNB1;MYC;IL1B;VCAM1;PRKCD;CXCL8;XRCC6;PRKCB;PECAM1;BIRC5;NOS3;PTPN1;HGF;IL1A;MPO;CRP;CD80;JAK1;IRS1;MTOR;CCR2;BCL2L11;TRAF2;CDC42;CD28"]
["R-HSA-5357801","Programmed Cell Death",19,87,215,11092,11.266933974873,{"v":2.84979011950846e-15,"d":"2.85E-15"},{"v":4.50836796906238e-13,"d":"4.51E-13"},"STAT3;AKT1;BCL2;BCL2L1;BAX;CASP9;MAPK3;MAPK1;CASP3;MAPK8;CTNNB1;IL1B;PRKCD;IL1A;CFLAR;BCL2L11;TNFSF10;TNFRSF10A;TRAF2"]
["R-HSA-109581","Apoptosis",17,87,182,11092,11.9088038398383,{"v":3.88619394093056e-14,"d":"3.89E-14"},{"v":5.12329901212679e-12,"d":"5.12E-12"},"STAT3;AKT1;BCL2;BCL2L1;BAX;CASP9;MAPK3;MAPK1;CASP3;MAPK8;CTNNB1;PRKCD;CFLAR;BCL2L11;TNFSF10;TNFRSF10A;TRAF2"]
["R-HSA-162582","Signal Transduction",53,87,2581,11092,2.61805323607084,{"v":5.3082849952336e-14,"d":"5.31E-14"},{"v":5.99836204461397e-12,"d":"6.00E-12"},"NCOA2;RELA;STAT3;AKT1;VEGFA;CCND1;BCL2;BCL2L1;CDKN1A;BAX;CASP9;MMP2;MMP9;MAPK3;MAPK1;IL6;CASP3;MAPK8;NFKBIA;STAT1;EDN1;FOXO1;PPARG;CTNNB1;MYC;PRKCD;CXCL8;PRKCB;BIRC5;NOS3;PTPN1;HGF;PLAT;PRKAG2;CD80;CCNE1;NTRK1;SREBF1;JAK1;AGTR1;IRS1;CFLAR;MTOR;CCR2;BCL2L11;TNFSF10;TNFRSF10A;TRAF2;CDC42;CD28;NR1H3;SPARC;TGFA"]
["R-HSA-109606","Intrinsic Pathway for Apoptosis",11,87,55,11092,25.4988505747126,{"v":3.2564827825942e-13,"d":"3.26E-13"},{"v":3.21984735129001e-11,"d":"3.22E-11"},"STAT3;AKT1;BCL2;BCL2L1;BAX;CASP9;MAPK3;MAPK1;CASP3;MAPK8;BCL2L11"]
["R-HSA-6783783","Interleukin-10 signaling",10,87,47,11092,27.1264367816092,{"v":2.11768210605064e-12,"d":"2.12E-12"},{"v":1.86120727320673e-10,"d":"1.86E-10"},"PTGS2;STAT3;IL10;IL6;IL1B;CXCL8;IL1A;CD80;JAK1;CCR2"]
["R-HSA-9006934","Signaling by Receptor Tyrosine Kinases",22,87,521,11092,5.38363447834624,{"v":5.09106260744357e-11,"d":"5.09E-11"},{"v":4.02703052248787e-09,"d":"4.03E-09"},"STAT3;AKT1;VEGFA;BAX;MMP9;MAPK3;MAPK1;STAT1;CTNNB1;MYC;PRKCD;PRKCB;NOS3;PTPN1;HGF;PLAT;NTRK1;IRS1;MTOR;CDC42;SPARC;TGFA"]
["R-HSA-5663202","Diseases of signal transduction by growth factor receptors and second messengers",19,87,433,11092,5.59443603833187,{"v":7.03936947785019e-10,"d":"7.04E-10"},{"v":5.06194659725409e-08,"d":"5.06E-08"},"STAT3;AKT1;BCL2L1;CDKN1A;CASP9;MAPK3;MAPK1;STAT1;FOXO1;CTNNB1;MYC;BCL2A1;HGF;CD80;IRS1;MTOR;BCL2L11;CD28;TGFA"]
["R-HSA-1643685","Disease",39,87,1884,11092,2.63921224101325,{"v":1.12818210687068e-09,"d":"1.13E-09"},{"v":7.43660038778921e-08,"d":"7.44E-08"},"RELA;STAT3;AKT1;VEGFA;CCND1;BCL2L1;CDKN1A;CASP9;MAPK3;MAPK1;IL10;IL6;MAPK8;NFKBIA;STAT1;FOXO1;CTNNB1;MYC;IL1B;BRCA1;XRCC6;BCL2A1;HGF;CYP1B1;IL1A;NFE2L2;CD80;CCNE1;JAK1;IRS1;MTOR;BCL2L11;TRAF2;CDC42;BSG;CD28;BRCA2;TGFA;CD320"]
["R-HSA-212436","Generic Transcription Pathway",30,87,1243,11092,3.07709379421311,{"v":7.37344331560152e-09,"d":"7.37E-09"},{"v":4.05657868719696e-07,"d":"4.06E-07"},"RELA;AKT1;VEGFA;CCND1;CDKN1A;BAX;MAPK3;MAPK1;IL6;CAT;STAT1;FOXO1;PPARG;CTNNB1;MYC;BRCA1;PRKCB;BIRC5;PTPN1;CCNB1;DDIT3;PRKAG2;PPARA;CCNE1;SREBF1;MTOR;BCL2L11;TNFRSF10A;NR1H3;TGFA"]
["R-HSA-2219528","PI3K/AKT Signaling in Cancer",10,87,104,11092,12.2590627763042,{"v":7.4337212074551e-09,"d":"7.43E-09"},{"v":4.05657868719696e-07,"d":"4.06E-07"},"AKT1;CDKN1A;CASP9;FOXO1;HGF;CD80;IRS1;MTOR;CD28;TGFA"]
["R-HSA-9009391","Extra-nuclear estrogen signaling",9,87,77,11092,14.9019256605464,{"v":7.69262709329385e-09,"d":"7.69E-09"},{"v":4.05657868719696e-07,"d":"4.06E-07"},"AKT1;CCND1;BCL2;MMP2;MMP9;MAPK3;MAPK1;NOS3;TGFA"]
["R-HSA-5218859","Regulated Necrosis",8,87,60,11092,16.9992337164751,{"v":1.89529495242429e-08,"d":"1.90E-08"},{"v":9.36986442104759e-07,"d":"9.37E-07"},"BAX;CASP3;IL1B;IL1A;CFLAR;TNFSF10;TNFRSF10A;TRAF2"]
["R-HSA-9634638","Estrogen-dependent nuclear events downstream of ESR-membrane signaling",6,87,24,11092,31.8735632183908,{"v":2.35006081725242e-08,"d":"2.35E-08"},{"v":1.03272117024815e-06,"d":"1.03E-06"},"AKT1;CCND1;BCL2;MAPK3;MAPK1;TGFA"]
["R-HSA-982772","Growth hormone receptor signaling",6,87,24,11092,31.8735632183908,{"v":2.35006081725242e-08,"d":"2.35E-08"},{"v":1.03272117024815e-06,"d":"1.03E-06"},"STAT3;MAPK3;MAPK1;STAT1;PTPN1;IRS1"]
["R-HSA-73857","RNA Polymerase II Transcription",30,87,1366,11092,2.8000201948806,{"v":6.50786625318417e-08,"d":"6.51E-08"},{"v":2.70932747698351e-06,"d":"2.71E-06"},"RELA;AKT1;VEGFA;CCND1;CDKN1A;BAX;MAPK3;MAPK1;IL6;CAT;STAT1;FOXO1;PPARG;CTNNB1;MYC;BRCA1;PRKCB;BIRC5;PTPN1;CCNB1;DDIT3;PRKAG2;PPARA;CCNE1;SREBF1;MTOR;BCL2L11;TNFRSF10A;NR1H3;TGFA"]
["R-HSA-5357769","Caspase activation via extrinsic apoptotic signalling pathway",6,87,29,11092,26.3781212841855,{"v":8.03769673198017e-08,"d":"8.04E-08"},{"v":3.17890905749816e-06,"d":"3.18E-06"},"CASP9;CASP3;CFLAR;TNFSF10;TNFRSF10A;TRAF2"]
["R-HSA-9006925","Intracellular signaling by second messengers",14,87,309,11092,5.77643864152066,{"v":1.09479762801807e-07,"d":"1.09E-07"},{"v":4.12373773220138e-06,"d":"4.12E-06"},"AKT1;CDKN1A;CASP9;MAPK3;MAPK1;FOXO1;PPARG;PRKCD;HGF;CD80;IRS1;MTOR;CD28;TGFA"]
["R-HSA-1257604","PIP3 activates AKT signaling",13,87,267,11092,6.20758534590383,{"v":1.4223728157056e-07,"d":"1.42E-07"},{"v":5.1140768055597e-06,"d":"5.11E-06"},"AKT1;CDKN1A;CASP9;MAPK3;MAPK1;FOXO1;PPARG;HGF;CD80;IRS1;MTOR;CD28;TGFA"]
["R-HSA-111471","Apoptotic factor-mediated response",5,87,20,11092,31.8735632183908,{"v":3.73537005402969e-07,"d":"3.74E-07"},{"v":1.28464248379891e-05,"d":"1.28E-05"},"BAX;CASP9;MAPK3;MAPK1;CASP3"]
["R-HSA-111453","BH3-only proteins associate with and inactivate anti-apoptotic BCL-2 members",4,87,9,11092,56.6641123882503,{"v":4.31761307738455e-07,"d":"4.32E-07"},{"v":1.42301331008799e-05,"d":"1.42E-05"},"STAT3;BCL2;BCL2L1;BCL2L11"]
["R-HSA-9006931","Signaling by Nuclear Receptors",13,87,299,11092,5.5432283858071,{"v":5.22988149889859e-07,"d":"5.23E-07"},{"v":1.65473450625151e-05,"d":"1.65E-05"},"NCOA2;AKT1;CCND1;BCL2;MMP2;MMP9;MAPK3;MAPK1;MYC;NOS3;SREBF1;NR1H3;TGFA"]
["R-HSA-74160","Gene expression (Transcription)",30,87,1508,11092,2.53635781578707,{"v":5.85790410220223e-07,"d":"5.86E-07"},{"v":1.78215467109306e-05,"d":"1.78E-05"},"RELA;AKT1;VEGFA;CCND1;CDKN1A;BAX;MAPK3;MAPK1;IL6;CAT;STAT1;FOXO1;PPARG;CTNNB1;MYC;BRCA1;PRKCB;BIRC5;PTPN1;CCNB1;DDIT3;PRKAG2;PPARA;CCNE1;SREBF1;MTOR;BCL2L11;TNFRSF10A;NR1H3;TGFA"]
["R-HSA-9614085","FOXO-mediated transcription",7,87,65,11092,13.7301503094607,{"v":6.88829786752494e-07,"d":"6.89E-07"},{"v":2.01801615304156e-05,"d":"2.02E-05"},"AKT1;CDKN1A;CAT;FOXO1;DDIT3;SREBF1;BCL2L11"]
["R-HSA-4420097","VEGFA-VEGFR2 Pathway",8,87,99,11092,10.3025658887728,{"v":9.89799305944733e-07,"d":"9.90E-07"},{"v":2.79618303929387e-05,"d":"2.80E-05"},"AKT1;VEGFA;CTNNB1;PRKCD;PRKCB;NOS3;MTOR;CDC42"]
["R-HSA-1059683","Interleukin-6 signaling",4,87,11,11092,46.3615464994775,{"v":1.11731354293171e-06,"d":"1.12E-06"},{"v":2.8509516530935e-05,"d":"2.85E-05"},"STAT3;IL6;STAT1;JAK1"]
["R-HSA-3371378","Regulation by c-FLIP",4,87,11,11092,46.3615464994775,{"v":1.11731354293171e-06,"d":"1.12E-06"},{"v":2.8509516530935e-05,"d":"2.85E-05"},"CFLAR;TNFSF10;TNFRSF10A;TRAF2"]
["R-HSA-69416","Dimerization of procaspase-8",4,87,11,11092,46.3615464994775,{"v":1.11731354293171e-06,"d":"1.12E-06"},{"v":2.8509516530935e-05,"d":"2.85E-05"},"CFLAR;TNFSF10;TNFRSF10A;TRAF2"]
["R-HSA-5674400","Constitutive Signaling by AKT1 E17K in Cancer",5,87,25,11092,25.4988505747126,{"v":1.24116088887157e-06,"d":"1.24E-06"},{"v":2.97573190430212e-05,"d":"2.98E-05"},"AKT1;CDKN1A;CASP9;FOXO1;MTOR"]
["R-HSA-8939211","ESR-mediated signaling",11,87,223,11092,6.28895417761971,{"v":1.24145578814121e-06,"d":"1.24E-06"},{"v":2.97573190430212e-05,"d":"2.98E-05"},"NCOA2;AKT1;CCND1;BCL2;MMP2;MMP9;MAPK3;MAPK1;MYC;NOS3;TGFA"]
["R-HSA-6811558","PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling",8,87,106,11092,9.62220776404251,{"v":1.66773959020595e-06,"d":"1.67E-06"},{"v":3.77402752424638e-05,"d":"3.77E-05"},"AKT1;MAPK3;MAPK1;HGF;CD80;IRS1;CD28;TGFA"]
["R-HSA-73887","Death Receptor Signalling",9,87,143,11092,8.02411381721727,{"v":1.66992368329486e-06,"d":"1.67E-06"},{"v":3.77402752424638e-05,"d":"3.77E-05"},"RELA;CASP3;MAPK8;NFKBIA;CFLAR;BCL2L11;TNFSF10;TNFRSF10A;TRAF2"]
["R-HSA-194138","Signaling by VEGF",8,87,108,11092,9.44401873137505,{"v":1.92212780849592e-06,"d":"1.92E-06"},{"v":4.22334193477854e-05,"d":"4.22E-05"},"AKT1;VEGFA;CTNNB1;PRKCD;PRKCB;NOS3;MTOR;CDC42"]
["R-HSA-111461","Cytochrome c-mediated apoptotic response",4,87,13,11092,39.2290008841733,{"v":2.39197689245431e-06,"d":"2.39E-06"},{"v":4.97908874192464e-05,"d":"4.98E-05"},"CASP9;MAPK3;MAPK1;CASP3"]
["R-HSA-5218900","CASP8 activity is inhibited",4,87,13,11092,39.2290008841733,{"v":2.39197689245431e-06,"d":"2.39E-06"},{"v":4.97908874192464e-05,"d":"4.98E-05"},"CFLAR;TNFSF10;TNFRSF10A;TRAF2"]
["R-HSA-2559582","Senescence-Associated Secretory Phenotype (SASP)",8,87,112,11092,9.10673234811166,{"v":2.53112753591486e-06,"d":"2.53E-06"},{"v":5.13364584848372e-05,"d":"5.13E-05"},"RELA;STAT3;CDKN1A;MAPK3;MAPK1;IL6;CXCL8;IL1A"]
["R-HSA-199418","Negative regulation of the PI3K/AKT network",8,87,113,11092,9.02614179635846,{"v":2.70672519077006e-06,"d":"2.71E-06"},{"v":5.35254906474779e-05,"d":"5.35E-05"},"AKT1;MAPK3;MAPK1;HGF;CD80;IRS1;CD28;TGFA"]
["R-HSA-2559583","Cellular Senescence",10,87,199,11092,6.40674637555594,{"v":3.32003966693503e-06,"d":"3.32E-06"},{"v":6.40524725986734e-05,"d":"6.41E-05"},"RELA;STAT3;CDKN1A;MAPK3;MAPK1;IL6;MAPK8;CXCL8;IL1A;CCNE1"]
["R-HSA-8878166","Transcriptional regulation by RUNX2",8,87,121,11092,8.4293720908141,{"v":4.52338181580113e-06,"d":"4.52E-06"},{"v":8.51903575309212e-05,"d":"8.52E-05"},"AKT1;CCND1;CDKN1A;BAX;MAPK3;MAPK1;STAT1;CCNB1"]
["R-HSA-2262752","Cellular responses to stress",19,87,759,11092,3.19155573728287,{"v":4.92137274614583e-06,"d":"4.92E-06"},{"v":9.05303684232873e-05,"d":"9.05E-05"},"NCOA2;RELA;STAT3;VEGFA;CDKN1A;MAPK3;MAPK1;IL6;MAPK8;CAT;PRKCD;CXCL8;DDIT3;IL1A;NFE2L2;PPARA;CCNE1;MTOR;EIF2S1"]
["R-HSA-389356","CD28 co-stimulation",5,87,33,11092,19.317311041449,{"v":5.27744975352867e-06,"d":"5.28E-06"},{"v":9.41558930037023e-05,"d":"9.42E-05"},"AKT1;CD80;MTOR;CDC42;CD28"]
["R-HSA-109582","Hemostasis",17,87,622,11092,3.48456961229996,{"v":5.35652994332061e-06,"d":"5.36E-06"},{"v":9.41558930037023e-05,"d":"9.42E-05"},"AKT1;VEGFA;PLAU;MAPK3;MAPK1;SELE;PRKCD;PRKCB;PECAM1;NOS3;PTPN1;HGF;PLAT;TNFRSF10A;CDC42;BSG;SPARC"]
["R-HSA-76002","Platelet activation, signaling and aggregation",11,87,263,11092,5.33245924566234,{"v":6.14413246321577e-06,"d":"6.14E-06"},0.000105652364747906,"AKT1;VEGFA;MAPK3;MAPK1;PRKCD;PRKCB;PECAM1;PTPN1;HGF;CDC42;SPARC"]
["R-HSA-2142753","Arachidonic acid metabolism",6,87,59,11092,12.9655172413793,{"v":6.31694802308638e-06,"d":"6.32E-06"},0.000105731232760823,"PTGS1;PTGS2;CYP1A1;CYP1B1;PON1;PTGES"]
["R-HSA-8953897","Cellular responses to stimuli",19,87,773,11092,3.13375265795304,{"v":6.41605457967066e-06,"d":"6.42E-06"},0.000105731232760823,"NCOA2;RELA;STAT3;VEGFA;CDKN1A;MAPK3;MAPK1;IL6;MAPK8;CAT;PRKCD;CXCL8;DDIT3;IL1A;NFE2L2;PPARA;CCNE1;MTOR;EIF2S1"]
["R-HSA-140534","Caspase activation via Death Receptors in the presence of ligand",4,87,19,11092,26.8408953418028,{"v":1.25087940613651e-05,"d":"1.25E-05"},0.000197889122050796,"CFLAR;TNFSF10;TNFRSF10A;TRAF2"]
["R-HSA-9725371","Nuclear events stimulated by ALK signaling in cancer",4,87,19,11092,26.8408953418028,{"v":1.25087940613651e-05,"d":"1.25E-05"},0.000197889122050796,"STAT3;MAPK3;MAPK1;BCL2A1"]
["R-HSA-168249","Innate Immune System",22,87,1067,11092,2.62874748192914,{"v":1.74404115262184e-05,"d":"1.74E-05"},0.000270497363083113,"RELA;BCL2;BCL2L1;CASP9;PLAU;MMP9;MAPK3;MAPK1;MAPK8;NFKBIA;CAT;CTNNB1;IL1B;PRKCD;XRCC6;PECAM1;NOS3;MPO;CRP;CCR2;TRAF2;CDC42"]
["R-HSA-389357","CD28 dependent PI3K/Akt signaling",4,87,22,11092,23.1807732497388,{"v":2.31869047254223e-05,"d":"2.32E-05"},0.00035270849303479,"AKT1;CD80;MTOR;CD28"]
["R-HSA-163680","AMPK inhibits chREBP transcriptional activation activity",3,87,8,11092,47.8103448275862,{"v":2.53716229116511e-05,"d":"2.54E-05"},0.000364890067693019,"PRKAG2;ADIPOR1;ADIPOR2"]
["R-HSA-75158","TRAIL  signaling",3,87,8,11092,47.8103448275862,{"v":2.53716229116511e-05,"d":"2.54E-05"},0.000364890067693019,"CFLAR;TNFSF10;TNFRSF10A"]
["R-HSA-8951430","RUNX3 regulates WNT signaling",3,87,8,11092,47.8103448275862,{"v":2.53716229116511e-05,"d":"2.54E-05"},0.000364890067693019,"CCND1;CTNNB1;MYC"]
["R-HSA-112409","RAF-independent MAPK1/3 activation",4,87,23,11092,22.1729135432284,{"v":2.79008152253338e-05,"d":"2.79E-05"},0.00039409901505784,"MAPK3;MAPK1;IL6;JAK1"]
["R-HSA-5668599","RHO GTPases Activate NADPH Oxidases",4,87,24,11092,21.2490421455939,{"v":3.32811633927232e-05,"d":"3.33E-05"},0.000453886211097311,"MAPK3;MAPK1;PRKCD;PRKCB"]
["R-HSA-6783589","Interleukin-6 family signaling",4,87,24,11092,21.2490421455939,{"v":3.32811633927232e-05,"d":"3.33E-05"},0.000453886211097311,"STAT3;IL6;STAT1;JAK1"]
["R-HSA-1989781","PPARA activates gene expression",7,87,117,11092,7.6278612830337,{"v":3.53249015867705e-05,"d":"3.53E-05"},0.000473593172120941,"NCOA2;PPARG;CYP1A1;AHR;PPARA;SREBF1;NR1H3"]
["R-HSA-112411","MAPK1 (ERK2) activation",3,87,9,11092,42.4980842911877,{"v":3.78415537136074e-05,"d":"3.78E-05"},0.000482784983668766,"MAPK1;IL6;JAK1"]
["R-HSA-448706","Interleukin-1 processing",3,87,9,11092,42.4980842911877,{"v":3.78415537136074e-05,"d":"3.78E-05"},0.000482784983668766,"RELA;IL1B;IL1A"]
["R-HSA-8985947","Interleukin-9 signaling",3,87,9,11092,42.4980842911877,{"v":3.78415537136074e-05,"d":"3.78E-05"},0.000482784983668766,"STAT3;STAT1;JAK1"]
["R-HSA-400206","Regulation of lipid metabolism by PPARalpha",7,87,119,11092,7.49966193373901,{"v":3.93989069836336e-05,"d":"3.94E-05"},0.000494675165461178,"NCOA2;PPARG;CYP1A1;AHR;PPARA;SREBF1;NR1H3"]
["R-HSA-5683057","MAPK family signaling cascades",11,87,325,11092,4.31519009725906,{"v":4.42655760801722e-05,"d":"4.43E-05"},0.000547094854365878,"BCL2L1;MAPK3;MAPK1;IL6;FOXO1;MYC;HGF;JAK1;IRS1;CDC42;TGFA"]
["R-HSA-381340","Transcriptional regulation of white adipocyte differentiation",6,87,84,11092,9.10673234811166,{"v":4.87341336001633e-05,"d":"4.87E-05"},0.00059305691811891,"NCOA2;RELA;PPARG;SLC2A4;PPARA;SREBF1"]
["R-HSA-110056","MAPK3 (ERK1) activation",3,87,10,11092,38.248275862069,{"v":5.37528067267996e-05,"d":"5.38E-05"},0.000616209711897079,"MAPK3;IL6;JAK1"]
["R-HSA-450341","Activation of the AP-1 family of transcription factors",3,87,10,11092,38.248275862069,{"v":5.37528067267996e-05,"d":"5.38E-05"},0.000616209711897079,"MAPK3;MAPK1;MAPK8"]
["R-HSA-74749","Signal attenuation",3,87,10,11092,38.248275862069,{"v":5.37528067267996e-05,"d":"5.38E-05"},0.000616209711897079,"MAPK3;MAPK1;IRS1"]
["R-HSA-9020958","Interleukin-21 signaling",3,87,10,11092,38.248275862069,{"v":5.37528067267996e-05,"d":"5.38E-05"},0.000616209711897079,"STAT3;STAT1;JAK1"]
["R-HSA-8848021","Signaling by PTK6",5,87,54,11092,11.8050234142188,{"v":6.17922216462903e-05,"d":"6.18E-05"},0.000687864421458145,"STAT3;AKT1;CCND1;PTPN1;CCNE1"]
["R-HSA-9006927","Signaling by Non-Receptor Tyrosine Kinases",5,87,54,11092,11.8050234142188,{"v":6.17922216462903e-05,"d":"6.18E-05"},0.000687864421458145,"STAT3;AKT1;CCND1;PTPN1;CCNE1"]
["R-HSA-5620971","Pyroptosis",4,87,28,11092,18.2134646962233,{"v":6.26121850126251e-05,"d":"6.26E-05"},0.000687864421458145,"BAX;CASP3;IL1B;IL1A"]
["R-HSA-9700206","Signaling by ALK in cancer",5,87,55,11092,11.5903866248694,{"v":6.7554703278237e-05,"d":"6.76E-05"},0.000722105003960614,"STAT3;MAPK3;MAPK1;BCL2A1;IRS1"]
["R-HSA-9725370","Signaling by ALK fusions and activated point mutants",5,87,55,11092,11.5903866248694,{"v":6.7554703278237e-05,"d":"6.76E-05"},0.000722105003960614,"STAT3;MAPK3;MAPK1;BCL2A1;IRS1"]
["R-HSA-5218920","VEGFR2 mediated vascular permeability",4,87,29,11092,17.585414189457,{"v":7.21970787053316e-05,"d":"7.22E-05"},0.000745275298545682,"AKT1;CTNNB1;NOS3;MTOR"]
["R-HSA-111458","Formation of apoptosome",3,87,11,11092,34.7711598746082,{"v":7.34911166707499e-05,"d":"7.35E-05"},0.000745275298545682,"CASP9;MAPK3;MAPK1"]
["R-HSA-9020956","Interleukin-27 signaling",3,87,11,11092,34.7711598746082,{"v":7.34911166707499e-05,"d":"7.35E-05"},0.000745275298545682,"STAT3;STAT1;JAK1"]
["R-HSA-9627069","Regulation of the apoptosome activity",3,87,11,11092,34.7711598746082,{"v":7.34911166707499e-05,"d":"7.35E-05"},0.000745275298545682,"CASP9;MAPK3;MAPK1"]
["R-HSA-447115","Interleukin-12 family signaling",5,87,57,11092,11.1837063924178,{"v":8.03163693376021e-05,"d":"8.03E-05"},0.000804180356279029,"STAT3;IL10;STAT1;JAK1;CDC42"]
["R-HSA-114452","Activation of BH3-only proteins",4,87,30,11092,16.9992337164751,{"v":8.28077137731308e-05,"d":"8.28E-05"},0.000818761269931831,"AKT1;BCL2;MAPK8;BCL2L11"]
["R-HSA-3108232","SUMO E3 ligases SUMOylate target proteins",8,87,182,11092,5.60414298345333,{"v":8.71821018370993e-05,"d":"8.72E-05"},0.000851370895717846,"NCOA2;RELA;NFKBIA;PPARG;BRCA1;BIRC5;PPARA;NR1H3"]
["R-HSA-5675482","Regulation of necroptotic cell death",4,87,31,11092,16.4508713385243,{"v":9.45088490319114e-05,"d":"9.45E-05"},0.000906698547574119,"CFLAR;TNFSF10;TNFRSF10A;TRAF2"]
["R-HSA-170968","Frs2-mediated activation",3,87,12,11092,31.8735632183908,{"v":9.74328401312265e-05,"d":"9.74E-05"},0.000906698547574119,"MAPK3;MAPK1;NTRK1"]
["R-HSA-389359","CD28 dependent Vav1 pathway",3,87,12,11092,31.8735632183908,{"v":9.74328401312265e-05,"d":"9.74E-05"},0.000906698547574119,"CD80;CDC42;CD28"]
["R-HSA-8984722","Interleukin-35 Signalling",3,87,12,11092,31.8735632183908,{"v":9.74328401312265e-05,"d":"9.74E-05"},0.000906698547574119,"STAT3;STAT1;JAK1"]
["R-HSA-5213460","RIPK1-mediated regulated necrosis",4,87,32,11092,15.9367816091954,0.000107366466365005,0.000987521801101382,"CFLAR;TNFSF10;TNFRSF10A;TRAF2"]
["R-HSA-2990846","SUMOylation",8,87,188,11092,5.42528735632184,0.000109338864882124,0.000994103932434024,"NCOA2;RELA;NFKBIA;PPARG;BRCA1;BIRC5;PPARA;NR1H3"]
["R-HSA-162658","Golgi Cisternae Pericentriolar Stack Reorganization",3,87,14,11092,27.320197044335,0.000159385922742259,0.0013854314822981,"MAPK3;MAPK1;CCNB1"]
["R-HSA-169893","Prolonged ERK activation events",3,87,14,11092,27.320197044335,0.000159385922742259,0.0013854314822981,"MAPK3;MAPK1;NTRK1"]
["R-HSA-198323","AKT phosphorylates targets in the cytosol",3,87,14,11092,27.320197044335,0.000159385922742259,0.0013854314822981,"AKT1;CDKN1A;CASP9"]
["R-HSA-877312","Regulation of IFNG signaling",3,87,14,11092,27.320197044335,0.000159385922742259,0.0013854314822981,"STAT1;PTPN1;JAK1"]
["R-HSA-9658195","Leishmania infection",9,87,254,11092,4.51751289709476,0.000162418081688021,0.00139644241973071,"RELA;MAPK3;MAPK1;IL10;IL6;MAPK8;IL1B;IL1A;CDC42"]
["R-HSA-1266695","Interleukin-7 signaling",4,87,36,11092,14.1660280970626,0.000171720838608005,0.00146055035848314,"STAT3;HGF;JAK1;IRS1"]
["R-HSA-2162123","Synthesis of Prostaglandins (PG) and Thromboxanes (TX)",3,87,15,11092,25.4988505747126,0.000198104387351409,0.00166702734462729,"PTGS1;PTGS2;PTGES"]
["R-HSA-388841","Costimulation by the CD28 family",5,87,69,11092,9.23871397634516,0.000200253371983709,0.0016673728130433,"AKT1;CD80;MTOR;CDC42;CD28"]
["R-HSA-8864260","Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors",4,87,38,11092,13.4204476709014,0.000212632358779987,0.00175200203953094,"VEGFA;CDKN1A;MYC;TGFA"]
["R-HSA-9614657","FOXO-mediated transcription of cell death genes",3,87,16,11092,23.9051724137931,0.000242440754610845,0.00197701687522864,"FOXO1;DDIT3;BCL2L11"]
["R-HSA-8853884","Transcriptional Regulation by VENTX",4,87,41,11092,12.4384636949818,0.000286543200498896,0.00231281297545537,"RELA;CCND1;IL6;CTNNB1"]
["R-HSA-9659787","Aberrant regulation of mitotic G1/S transition in cancer due to RB1 defects",3,87,17,11092,22.498985801217,0.000292726608082001,0.00231546746992863,"CCND1;CDKN1A;CCNE1"]
["R-HSA-9661069","Defective binding of RB1 mutants to E2F1,(E2F2, E2F3)",3,87,17,11092,22.498985801217,0.000292726608082001,0.00231546746992863,"CCND1;CDKN1A;CCNE1"]
["R-HSA-1368082","RORA activates gene expression",3,87,18,11092,21.2490421455939,0.000349284987997877,0.00273548936144872,"NCOA2;PPARA;SREBF1"]
["R-HSA-2219530","Constitutive Signaling by Aberrant PI3K in Cancer",5,87,78,11092,8.1727085175361,0.000355956844968082,0.00276041043499758,"HGF;CD80;IRS1;CD28;TGFA"]
["R-HSA-8978868","Fatty acid metabolism",7,87,177,11092,5.04214559386973,0.000467211173533921,0.00358800037150807,"PTGS1;PTGS2;CYP1A1;CYP1B1;PRKAG2;PON1;PTGES"]
["R-HSA-69202","Cyclin E associated events during G1/S transition ",5,87,83,11092,7.68037667913031,0.000474773270211093,0.00361101593016322,"AKT1;CCND1;CDKN1A;MYC;CCNE1"]
["R-HSA-6791312","TP53 Regulates Transcription of Cell Cycle Genes",4,87,48,11092,10.6245210727969,0.00052805888823139,0.00384498274782627,"CDKN1A;BAX;CCNB1;CCNE1"]
["R-HSA-168142","Toll Like Receptor 10 (TLR10) Cascade",5,87,85,11092,7.49966193373901,0.000529839594833202,0.00384498274782627,"RELA;MAPK3;MAPK1;MAPK8;NFKBIA"]
["R-HSA-168176","Toll Like Receptor 5 (TLR5) Cascade",5,87,85,11092,7.49966193373901,0.000529839594833202,0.00384498274782627,"RELA;MAPK3;MAPK1;MAPK8;NFKBIA"]
["R-HSA-69656","Cyclin A:Cdk2-associated events at S phase entry",5,87,85,11092,7.49966193373901,0.000529839594833202,0.00384498274782627,"AKT1;CCND1;CDKN1A;MYC;CCNE1"]
["R-HSA-975871","MyD88 cascade initiated on plasma membrane",5,87,85,11092,7.49966193373901,0.000529839594833202,0.00384498274782627,"RELA;MAPK3;MAPK1;MAPK8;NFKBIA"]
["R-HSA-3700989","Transcriptional Regulation by TP53",10,87,365,11092,3.49299322941269,0.000552063810405858,0.0039528835253593,"AKT1;CDKN1A;BAX;BRCA1;BIRC5;CCNB1;PRKAG2;CCNE1;MTOR;TNFRSF10A"]
["R-HSA-69206","G1/S Transition",6,87,131,11092,5.83943142932351,0.00055876716785868,0.0039528835253593,"AKT1;CCND1;CDKN1A;MYC;CCNB1;CCNE1"]
["R-HSA-5218921","VEGFR2 mediated cell proliferation",3,87,21,11092,18.2134646962233,0.000559700322174768,0.0039528835253593,"VEGFA;PRKCD;PRKCB"]
["R-HSA-8866911","TFAP2 (AP-2) family regulates transcription of cell cycle factors",2,87,5,11092,50.9977011494253,0.000598916892812399,0.00419241824968679,"CDKN1A;MYC"]
["R-HSA-166520","Signaling by NTRKs",6,87,134,11092,5.70869788986104,0.000629882478672886,0.00437050035640573,"STAT3;BAX;MAPK3;MAPK1;NTRK1;IRS1"]
["R-HSA-877300","Interferon gamma signaling",5,87,91,11092,7.00517872931666,0.000724075935873786,0.00493744883858763,"STAT1;VCAM1;PRKCD;PTPN1;JAK1"]
["R-HSA-975138","TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation",5,87,91,11092,7.00517872931666,0.000724075935873786,0.00493744883858763,"RELA;MAPK3;MAPK1;MAPK8;NFKBIA"]
["R-HSA-975155","MyD88 dependent cascade initiated on endosome",5,87,92,11092,6.92903548225887,0.000761015855551093,0.00514498753624713,"RELA;MAPK3;MAPK1;MAPK8;NFKBIA"]
["R-HSA-168181","Toll Like Receptor 7/8 (TLR7/8) Cascade",5,87,93,11092,6.85452972438512,0.000799346975343847,0.00535833438556765,"RELA;MAPK3;MAPK1;MAPK8;NFKBIA"]
["R-HSA-446652","Interleukin-1 family signaling",6,87,141,11092,5.42528735632184,0.000823175033170633,0.00547169286754597,"RELA;STAT3;MAPK8;NFKBIA;IL1B;IL1A"]
["R-HSA-622312","Inflammasomes",3,87,24,11092,15.9367816091954,0.000837405307865806,0.00548537078658921,"RELA;BCL2;BCL2L1"]
["R-HSA-168164","Toll Like Receptor 3 (TLR3) Cascade",5,87,94,11092,6.7816091954023,0.000839102231576857,0.00548537078658921,"RELA;MAPK3;MAPK1;MAPK8;NFKBIA"]
["R-HSA-111459","Activation of caspases through apoptosome-mediated cleavage",2,87,6,11092,42.4980842911877,0.000893792826992296,0.00565592100920725,"CASP9;CASP3"]
["R-HSA-5660668","CLEC7A/inflammasome pathway",2,87,6,11092,42.4980842911877,0.000893792826992296,0.00565592100920725,"RELA;IL1B"]
["R-HSA-5674499","Negative feedback regulation of MAPK pathway",2,87,6,11092,42.4980842911877,0.000893792826992296,0.00565592100920725,"MAPK3;MAPK1"]
["R-HSA-8849470","PTK6 Regulates Cell Cycle",2,87,6,11092,42.4980842911877,0.000893792826992296,0.00565592100920725,"CCND1;CCNE1"]
["R-HSA-168138","Toll Like Receptor 9 (TLR9) Cascade",5,87,96,11092,6.64032567049808,0.000923018103314675,0.00579450253747546,"RELA;MAPK3;MAPK1;MAPK8;NFKBIA"]
["R-HSA-8854691","Interleukin-20 family signaling",3,87,25,11092,15.2993103448276,0.000946226392436711,0.00580205485594913,"STAT3;STAT1;JAK1"]
["R-HSA-933542","TRAF6 mediated NF-kB activation",3,87,25,11092,15.2993103448276,0.000946226392436711,0.00580205485594913,"RELA;NFKBIA;TRAF2"]
["R-HSA-9705462","Inactivation of CSF3 (G-CSF) signaling",3,87,25,11092,15.2993103448276,0.000946226392436711,0.00580205485594913,"STAT3;STAT1;JAK1"]
["R-HSA-193704","p75 NTR receptor-mediated signalling",5,87,97,11092,6.57186870482285,0.000967245773741763,0.00584039242007431,"RELA;CASP3;MAPK8;NFKBIA;BCL2L11"]
["R-HSA-8878159","Transcriptional regulation by RUNX3",5,87,97,11092,6.57186870482285,0.000967245773741763,0.00584039242007431,"CCND1;CDKN1A;CTNNB1;MYC;BCL2L11"]
["R-HSA-166166","MyD88-independent TLR4 cascade ",5,87,99,11092,6.43910368048299,0.00106040988221889,0.00618615735860742,"RELA;MAPK3;MAPK1;MAPK8;NFKBIA"]
["R-HSA-937061","TRIF(TICAM1)-mediated TLR4 signaling ",5,87,99,11092,6.43910368048299,0.00106040988221889,0.00618615735860742,"RELA;MAPK3;MAPK1;MAPK8;NFKBIA"]
["R-HSA-912694","Regulation of IFNA/IFNB signaling",3,87,26,11092,14.710875331565,0.00106361239035475,0.00618615735860742,"STAT1;PTPN1;JAK1"]
["R-HSA-9660826","Purinergic signaling in leishmaniasis infection",3,87,26,11092,14.710875331565,0.00106361239035475,0.00618615735860742,"RELA;IL1B;IL1A"]
["R-HSA-9664424","Cell recruitment (pro-inflammatory response)",3,87,26,11092,14.710875331565,0.00106361239035475,0.00618615735860742,"RELA;IL1B;IL1A"]
["R-HSA-453279","Mitotic G1 phase and G1/S transition",6,87,149,11092,5.13399676000926,0.00109702342888728,0.00633390899452434,"AKT1;CCND1;CDKN1A;MYC;CCNB1;CCNE1"]
["R-HSA-201556","Signaling by ALK",3,87,27,11092,14.1660280970626,0.00118981524428245,0.00669891365017889,"STAT3;MYC;IRS1"]
["R-HSA-211976","Endogenous sterols",3,87,27,11092,14.1660280970626,0.00118981524428245,0.00669891365017889,"NCOA2;CYP1B1;AHR"]
["R-HSA-166058","MyD88:MAL(TIRAP) cascade initiated on plasma membrane",5,87,102,11092,6.24971827811584,0.00121244209834962,0.00669891365017889,"RELA;MAPK3;MAPK1;MAPK8;NFKBIA"]
["R-HSA-168188","Toll Like Receptor TLR6:TLR2 Cascade",5,87,102,11092,6.24971827811584,0.00121244209834962,0.00669891365017889,"RELA;MAPK3;MAPK1;MAPK8;NFKBIA"]
["R-HSA-168643","Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways",4,87,60,11092,8.49961685823755,0.00123215527190082,0.00669891365017889,"RELA;BCL2;BCL2L1;CASP9"]
["R-HSA-111463","SMAC (DIABLO) binds to IAPs ",2,87,7,11092,36.4269293924466,0.00124493085534298,0.00669891365017889,"CASP9;CASP3"]
["R-HSA-111464","SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes ",2,87,7,11092,36.4269293924466,0.00124493085534298,0.00669891365017889,"CASP9;CASP3"]
["R-HSA-444257","RSK activation",2,87,7,11092,36.4269293924466,0.00124493085534298,0.00669891365017889,"MAPK3;MAPK1"]
["R-HSA-5603029","IkBA variant leads to EDA-ID",2,87,7,11092,36.4269293924466,0.00124493085534298,0.00669891365017889,"RELA;NFKBIA"]
["R-HSA-9635465","Suppression of apoptosis",2,87,7,11092,36.4269293924466,0.00124493085534298,0.00669891365017889,"MAPK3;MAPK1"]
["R-HSA-8943724","Regulation of PTEN gene transcription",4,87,61,11092,8.36027887695496,0.00131080869561507,0.00700574106913187,"MAPK3;MAPK1;PPARG;MTOR"]
["R-HSA-168179","Toll Like Receptor TLR1:TLR2 Cascade",5,87,105,11092,6.07115489874111,0.00138005052769171,0.00727746644936094,"RELA;MAPK3;MAPK1;MAPK8;NFKBIA"]
["R-HSA-181438","Toll Like Receptor 2 (TLR2) Cascade",5,87,105,11092,6.07115489874111,0.00138005052769171,0.00727746644936094,"RELA;MAPK3;MAPK1;MAPK8;NFKBIA"]
["R-HSA-211945","Phase I - Functionalization of compounds",5,87,106,11092,6.01387985252657,0.00143954519802479,0.0075409288187921,"PTGS1;NCOA2;CYP1A1;CYP1B1;AHR"]
["R-HSA-9615017","FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes",3,87,29,11092,13.1890606420927,0.00146964298055131,0.00764794472115847,"CAT;FOXO1;SREBF1"]
["R-HSA-1834949","Cytosolic sensors of pathogen-associated DNA ",4,87,64,11092,7.9683908045977,0.00156776185687245,0.00810522633193535,"RELA;NFKBIA;CTNNB1;XRCC6"]
["R-HSA-9711123","Cellular response to chemical stress",6,87,160,11092,4.78103448275862,0.00158193163625003,0.00812537613164786,"NCOA2;STAT3;CAT;PRKCD;NFE2L2;PPARA"]
["R-HSA-4090294","SUMOylation of intracellular receptors",3,87,30,11092,12.7494252873563,0.00162373578797111,0.00821570707040265,"PPARG;PPARA;NR1H3"]
["R-HSA-9674555","Signaling by CSF3 (G-CSF)",3,87,30,11092,12.7494252873563,0.00162373578797111,0.00821570707040265,"STAT3;STAT1;JAK1"]
["R-HSA-111469","SMAC, XIAP-regulated apoptotic response",2,87,8,11092,31.8735632183908,0.00165145059948675,0.00821570707040265,"CASP9;CASP3"]
["R-HSA-2142670","Synthesis of epoxy (EET) and dihydroxyeicosatrienoic acids (DHET)",2,87,8,11092,31.8735632183908,0.00165145059948675,0.00821570707040265,"CYP1A1;CYP1B1"]
["R-HSA-4411364","Binding of TCF/LEF:CTNNB1 to target gene promoters",2,87,8,11092,31.8735632183908,0.00165145059948675,0.00821570707040265,"CTNNB1;MYC"]
["R-HSA-211897","Cytochrome P450 - arranged by substrate type",4,87,66,11092,7.72692441657959,0.00175735042339447,0.00868790115565642,"NCOA2;CYP1A1;CYP1B1;AHR"]
["R-HSA-5684996","MAPK1/MAPK3 signaling",8,87,286,11092,3.56627280765212,0.00177563907070433,0.00872379195606909,"BCL2L1;MAPK3;MAPK1;IL6;HGF;JAK1;IRS1;TGFA"]
["R-HSA-450282","MAPK targets/ Nuclear events mediated by MAP kinases",3,87,31,11092,12.3381535038932,0.00178758153142888,0.00872825303308794,"MAPK3;MAPK1;MAPK8"]
["R-HSA-2173796","SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription",3,87,32,11092,11.9525862068966,0.00196139688298721,0.00940281778450233,"MAPK3;MAPK1;MYC"]
["R-HSA-2871796","FCERI mediated MAPK activation",3,87,32,11092,11.9525862068966,0.00196139688298721,0.00940281778450233,"MAPK3;MAPK1;MAPK8"]
["R-HSA-381042","PERK regulates gene expression",3,87,32,11092,11.9525862068966,0.00196139688298721,0.00940281778450233,"CXCL8;DDIT3;EIF2S1"]
["R-HSA-187037","Signaling by NTRK1 (TRKA)",5,87,115,11092,5.5432283858071,0.0020635254590043,0.009771772330636,"STAT3;MAPK3;MAPK1;NTRK1;IRS1"]
["R-HSA-198203","PI3K/AKT activation",2,87,9,11092,28.3320561941252,0.00211248175542194,0.009771772330636,"NTRK1;IRS1"]
["R-HSA-198693","AKT phosphorylates targets in the nucleus",2,87,9,11092,28.3320561941252,0.00211248175542194,0.009771772330636,"AKT1;FOXO1"]
["R-HSA-2142816","Synthesis of (16-20)-hydroxyeicosatetraenoic acids (HETE)",2,87,9,11092,28.3320561941252,0.00211248175542194,0.009771772330636,"CYP1A1;CYP1B1"]
["R-HSA-9029558","NR1H2 & NR1H3 regulate gene expression linked to lipogenesis",2,87,9,11092,28.3320561941252,0.00211248175542194,0.009771772330636,"SREBF1;NR1H3"]
["R-HSA-9662834","CD163 mediating an anti-inflammatory response",2,87,9,11092,28.3320561941252,0.00211248175542194,0.009771772330636,"IL10;IL6"]
["R-HSA-187687","Signalling to ERKs",3,87,34,11092,11.2494929006085,0.00233976963637961,0.0107602196649783,"MAPK3;MAPK1;NTRK1"]
["R-HSA-1266738","Developmental Biology",18,87,1128,11092,2.03448275862069,0.00252977303690258,0.011566765735202,"NCOA2;RELA;STAT3;AKT1;CDKN1A;MMP2;MMP9;MAPK3;MAPK1;MAPK8;FOXO1;PPARG;CTNNB1;MYC;SLC2A4;PPARA;SREBF1;CDC42"]
["R-HSA-418889","Caspase activation via Dependence Receptors in the absence of ligand",2,87,10,11092,25.4988505747126,0.00262716399259573,0.0118747812465327,"CASP9;CASP3"]
["R-HSA-9702518","STAT5 activation downstream of FLT3 ITD mutants",2,87,10,11092,25.4988505747126,0.00262716399259573,0.0118747812465327,"BCL2L1;CDKN1A"]
["R-HSA-5663213","RHO GTPases Activate WASPs and WAVEs",3,87,36,11092,10.6245210727969,0.00276045510363268,0.0123362711128443,"MAPK3;MAPK1;CDC42"]
["R-HSA-9687139","Aberrant regulation of mitotic cell cycle due to RB1 defects",3,87,36,11092,10.6245210727969,0.00276045510363268,0.0123362711128443,"CCND1;CDKN1A;CCNE1"]
["R-HSA-9707564","Cytoprotection by HMOX1",5,87,124,11092,5.14089729328884,0.00286548547897696,0.0127337023251167,"NCOA2;STAT3;PRKCD;NFE2L2;PPARA"]
["R-HSA-2586552","Signaling by Leptin",2,87,11,11092,23.1807732497388,0.00319464685391239,0.0138637886634645,"STAT3;IRS1"]
["R-HSA-351906","Apoptotic cleavage of cell adhesion  proteins",2,87,11,11092,23.1807732497388,0.00319464685391239,0.0138637886634645,"CASP3;CTNNB1"]
["R-HSA-4755510","SUMOylation of immune response proteins",2,87,11,11092,23.1807732497388,0.00319464685391239,0.0138637886634645,"RELA;NFKBIA"]
["R-HSA-9614399","Regulation of localization of FOXO transcription factors",2,87,11,11092,23.1807732497388,0.00319464685391239,0.0138637886634645,"AKT1;FOXO1"]
["R-HSA-111465","Apoptotic cleavage of cellular proteins",3,87,38,11092,10.065335753176,0.00322495210376419,0.0138637886634645,"CASP3;CTNNB1;PRKCD"]
["R-HSA-9675126","Diseases of mitotic cell cycle",3,87,38,11092,10.065335753176,0.00322495210376419,0.0138637886634645,"CCND1;CDKN1A;CCNE1"]
["R-HSA-1474151","Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation",2,87,12,11092,21.2490421455939,0.00381408965666862,0.0161333952856945,"AKT1;NOS3"]
["R-HSA-9673767","Signaling by PDGFRA transmembrane, juxtamembrane and kinase domain mutants",2,87,12,11092,21.2490421455939,0.00381408965666862,0.0161333952856945,"STAT3;STAT1"]
["R-HSA-9673770","Signaling by PDGFRA extracellular domain mutants",2,87,12,11092,21.2490421455939,0.00381408965666862,0.0161333952856945,"STAT3;STAT1"]
["R-HSA-2454202","Fc epsilon receptor (FCERI) signaling",5,87,134,11092,4.75724824155087,0.0039979084164926,0.0166812756532624,"RELA;MAPK3;MAPK1;MAPK8;NFKBIA"]
["R-HSA-76005","Response to elevated platelet cytosolic Ca2+",5,87,134,11092,4.75724824155087,0.0039979084164926,0.0166812756532624,"VEGFA;PRKCB;PECAM1;HGF;SPARC"]
["R-HSA-165159","MTOR signalling",3,87,41,11092,9.32884777123633,0.00400688037183293,0.0166812756532624,"AKT1;PRKAG2;MTOR"]
["R-HSA-195258","RHO GTPase Effectors",8,87,327,11092,3.11912545256424,0.0040515626485619,0.0167789845812171,"NCOA2;MAPK3;MAPK1;CTNNB1;PRKCD;PRKCB;BIRC5;CDC42"]
["R-HSA-166016","Toll Like Receptor 4 (TLR4) Cascade",5,87,136,11092,4.68728870858688,0.00425798284852832,0.0175420022561766,"RELA;MAPK3;MAPK1;MAPK8;NFKBIA"]
["R-HSA-2426168","Activation of gene expression by SREBF (SREBP)",3,87,42,11092,9.10673234811166,0.00429088486678306,0.0175859581845876,"NCOA2;PPARA;SREBF1"]
["R-HSA-202670","ERKs are inactivated",2,87,13,11092,19.6145004420866,0.00448466139440785,0.0179159957726091,"MAPK3;MAPK1"]
["R-HSA-203615","eNOS activation",2,87,13,11092,19.6145004420866,0.00448466139440785,0.0179159957726091,"AKT1;NOS3"]
["R-HSA-209560","NF-kB is activated and signals survival",2,87,13,11092,19.6145004420866,0.00448466139440785,0.0179159957726091,"RELA;NFKBIA"]
["R-HSA-75205","Dissolution of Fibrin Clot",2,87,13,11092,19.6145004420866,0.00448466139440785,0.0179159957726091,"PLAU;PLAT"]
["R-HSA-879415","Advanced glycosylation endproduct receptor signaling",2,87,13,11092,19.6145004420866,0.00448466139440785,0.0179159957726091,"MAPK3;MAPK1"]
["R-HSA-1433557","Signaling by SCF-KIT",3,87,43,11092,8.89494787489976,0.00458682269087394,0.0181904971801529,"STAT3;MMP9;STAT1"]
["R-HSA-2029480","Fcgamma receptor (FCGR) dependent phagocytosis",4,87,86,11092,5.92996524993317,0.00459936717576559,0.0181904971801529,"MAPK3;MAPK1;PRKCD;CDC42"]
["R-HSA-913531","Interferon Signaling",6,87,199,11092,3.84404782533356,0.00468421004812955,0.018433881333684,"MAPK3;STAT1;VCAM1;PRKCD;PTPN1;JAK1"]
["R-HSA-6807070","PTEN Regulation",5,87,140,11092,4.55336617405583,0.00481407506224112,0.0188511553179838,"AKT1;MAPK3;MAPK1;PPARG;MTOR"]
["R-HSA-451927","Interleukin-2 family signaling",3,87,44,11092,8.69278996865204,0.00489483689008352,0.018979490098314,"STAT3;STAT1;JAK1"]
["R-HSA-5633008","TP53 Regulates Transcription of Cell Death Genes",3,87,44,11092,8.69278996865204,0.00489483689008352,0.018979490098314,"BAX;BIRC5;TNFRSF10A"]
["R-HSA-556833","Metabolism of lipids",13,87,742,11092,2.23372680236701,0.00496546726273167,0.0191594370966866,"PTGS1;PTGS2;NCOA2;PPARG;CYP1A1;CYP1B1;AHR;PRKAG2;PPARA;PON1;SREBF1;PTGES;NR1H3"]
["R-HSA-6804116","TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest",2,87,14,11092,18.2134646962233,0.00520554063968544,0.0198917036038221,"CDKN1A;CCNE1"]
["R-HSA-8983432","Interleukin-15 signaling",2,87,14,11092,18.2134646962233,0.00520554063968544,0.0198917036038221,"STAT3;JAK1"]
["R-HSA-2173793","Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer",3,87,46,11092,8.31484257871064,0.00554763926121207,0.0210970319981671,"MAPK3;MAPK1;MYC"]
["R-HSA-69231","Cyclin D associated events in G1",3,87,47,11092,8.13793103448276,0.00589268646898815,0.021783175664331,"CCND1;CDKN1A;CCNE1"]
["R-HSA-69236","G1 Phase",3,87,47,11092,8.13793103448276,0.00589268646898815,0.021783175664331,"CCND1;CDKN1A;CCNE1"]
["R-HSA-9020591","Interleukin-12 signaling",3,87,47,11092,8.13793103448276,0.00589268646898815,0.021783175664331,"IL10;JAK1;CDC42"]
["R-HSA-9707616","Heme signaling",3,87,47,11092,8.13793103448276,0.00589268646898815,0.021783175664331,"NCOA2;NFE2L2;PPARA"]
["R-HSA-111447","Activation of BAD and translocation to mitochondria ",2,87,15,11092,16.9992337164751,0.00597591544773683,0.021783175664331,"AKT1;BCL2"]
["R-HSA-1502540","Signaling by Activin",2,87,15,11092,16.9992337164751,0.00597591544773683,0.021783175664331,"MAPK3;MAPK1"]
["R-HSA-4419969","Depolymerisation of the Nuclear Lamina",2,87,15,11092,16.9992337164751,0.00597591544773683,0.021783175664331,"PRKCB;CCNB1"]
["R-HSA-8866910","TFAP2 (AP-2) family regulates transcription of growth factors and their receptors",2,87,15,11092,16.9992337164751,0.00597591544773683,0.021783175664331,"VEGFA;TGFA"]
["R-HSA-9648895","Response of EIF2AK1 (HRI) to heme deficiency",2,87,15,11092,16.9992337164751,0.00597591544773683,0.021783175664331,"DDIT3;EIF2S1"]
["R-HSA-5673001","RAF/MAP kinase cascade",7,87,280,11092,3.18735632183908,0.0063415967727852,0.0230101057214362,"BCL2L1;MAPK3;MAPK1;HGF;JAK1;IRS1;TGFA"]
["R-HSA-9018519","Estrogen-dependent gene expression",5,87,150,11092,4.24980842911877,0.00642753008851779,0.0232154168950574,"NCOA2;CCND1;BCL2;MYC;TGFA"]
["R-HSA-1295596","Spry regulation of FGF signaling",2,87,16,11092,15.9367816091954,0.00679498326104055,0.0242109538715454,"MAPK3;MAPK1"]
["R-HSA-193639","p75NTR signals via NF-kB",2,87,16,11092,15.9367816091954,0.00679498326104055,0.0242109538715454,"RELA;NFKBIA"]
["R-HSA-9703648","Signaling by FLT3 ITD and TKD mutants",2,87,16,11092,15.9367816091954,0.00679498326104055,0.0242109538715454,"BCL2L1;CDKN1A"]
["R-HSA-1640170","Cell Cycle",12,87,692,11092,2.21088299780745,0.00753423629406568,0.0265815925196569,"AKT1;CCND1;CDKN1A;MAPK3;MAPK1;MYC;BRCA1;PRKCB;BIRC5;CCNB1;CCNE1;BRCA2"]
["R-HSA-1810476","RIP-mediated NFkB activation via ZBP1",2,87,17,11092,14.999323867478,0.00766195081476836,0.0265815925196569,"RELA;NFKBIA"]
["R-HSA-202131","Metabolism of nitric oxide: NOS3 activation and regulation",2,87,17,11092,14.999323867478,0.00766195081476836,0.0265815925196569,"AKT1;NOS3"]
["R-HSA-9018677","Biosynthesis of DHA-derived SPMs",2,87,17,11092,14.999323867478,0.00766195081476836,0.0265815925196569,"PTGS2;CYP1A1"]
["R-HSA-9034015","Signaling by NTRK3 (TRKC)",2,87,17,11092,14.999323867478,0.00766195081476836,0.0265815925196569,"BAX;IRS1"]
["R-HSA-9617828","FOXO-mediated transcription of cell cycle genes",2,87,17,11092,14.999323867478,0.00766195081476836,0.0265815925196569,"CDKN1A;FOXO1"]
["R-HSA-383280","Nuclear Receptor transcription pathway",3,87,52,11092,7.35543766578249,0.00780909791064647,0.0268565062927016,"PPARG;PPARA;NR1H3"]
["R-HSA-75153","Apoptotic execution phase",3,87,52,11092,7.35543766578249,0.00780909791064647,0.0268565062927016,"CASP3;CTNNB1;PRKCD"]
["R-HSA-168898","Toll-like Receptor Cascades",5,87,158,11092,4.03462825549251,0.00796670968329346,0.0272799452791564,"RELA;MAPK3;MAPK1;MAPK8;NFKBIA"]
["R-HSA-5607764","CLEC7A (Dectin-1) signaling",4,87,101,11092,5.04927734152726,0.00809388869551079,0.0275959739575389,"RELA;NFKBIA;IL1B;PRKCD"]
["R-HSA-1839117","Signaling by cytosolic FGFR1 fusion mutants",2,87,18,11092,14.1660280970626,0.00857603404311467,0.0288665656515051,"STAT3;STAT1"]
["R-HSA-6804114","TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest",2,87,18,11092,14.1660280970626,0.00857603404311467,0.0288665656515051,"BAX;CCNB1"]
["R-HSA-881907","Gastrin-CREB signalling pathway via PKC and MAPK",2,87,18,11092,14.1660280970626,0.00857603404311467,0.0288665656515051,"MAPK3;MAPK1"]
["R-HSA-9020702","Interleukin-1 signaling",4,87,103,11092,4.95123312130343,0.00866196527162913,0.0289260550589472,"RELA;NFKBIA;IL1B;IL1A"]
["R-HSA-74751","Insulin receptor signalling cascade",3,87,54,11092,7.08301404853129,0.00866684582676422,0.0289260550589472,"MAPK3;MAPK1;IRS1"]
["R-HSA-69242","S Phase",5,87,163,11092,3.91086665256329,0.00904946246378505,0.0300761546590503,"AKT1;CCND1;CDKN1A;MYC;CCNE1"]
["R-HSA-1655829","Regulation of cholesterol biosynthesis by SREBP (SREBF)",3,87,55,11092,6.95423197492163,0.00911563773758072,0.0301693282444617,"NCOA2;PPARA;SREBF1"]
["R-HSA-1474244","Extracellular matrix organization",7,87,301,11092,2.96498262496659,0.00927490156736471,0.0305685297491062,"MMP2;MMP9;CASP3;VCAM1;PECAM1;BSG;SPARC"]
["R-HSA-9018678","Biosynthesis of specialized proresolving mediators (SPMs)",2,87,19,11092,13.4204476709014,0.00953645798649745,0.031300158785558,"PTGS2;CYP1A1"]
["R-HSA-8978934","Metabolism of cofactors",2,87,20,11092,12.7494252873563,0.010542456699623,0.0338993981119595,"AKT1;NOS3"]
["R-HSA-9669938","Signaling by KIT in disease",2,87,20,11092,12.7494252873563,0.010542456699623,0.0338993981119595,"STAT3;STAT1"]
["R-HSA-9670439","Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants",2,87,20,11092,12.7494252873563,0.010542456699623,0.0338993981119595,"STAT3;STAT1"]
["R-HSA-9671555","Signaling by PDGFR in disease",2,87,20,11092,12.7494252873563,0.010542456699623,0.0338993981119595,"STAT3;STAT1"]
["R-HSA-186797","Signaling by PDGF",3,87,58,11092,6.59453032104637,0.0105426699564375,0.0338993981119595,"STAT3;STAT1;PLAT"]
["R-HSA-9664407","Parasite infection",3,87,59,11092,6.48275862068965,0.0110454807706486,0.0350882541750323,"MAPK3;MAPK1;CDC42"]
["R-HSA-9664417","Leishmania phagocytosis",3,87,59,11092,6.48275862068965,0.0110454807706486,0.0350882541750323,"MAPK3;MAPK1;CDC42"]
["R-HSA-9664422","FCGR3A-mediated phagocytosis",3,87,59,11092,6.48275862068965,0.0110454807706486,0.0350882541750323,"MAPK3;MAPK1;CDC42"]
["R-HSA-187577","SCF(Skp2)-mediated degradation of p27/p21",3,87,60,11092,6.37471264367816,0.0115619715863722,0.0359618787054195,"CCND1;CDKN1A;CCNE1"]
["R-HSA-1606322","ZBP1(DAI) mediated induction of type I IFNs",2,87,21,11092,12.1423097974822,0.0115932731604071,0.0359618787054195,"RELA;NFKBIA"]
["R-HSA-210745","Regulation of gene expression in beta cells",2,87,21,11092,12.1423097974822,0.0115932731604071,0.0359618787054195,"AKT1;FOXO1"]
["R-HSA-389513","CTLA4 inhibitory signaling",2,87,21,11092,12.1423097974822,0.0115932731604071,0.0359618787054195,"AKT1;CD80"]
["R-HSA-445144","Signal transduction by L1",2,87,21,11092,12.1423097974822,0.0115932731604071,0.0359618787054195,"MAPK3;MAPK1"]
["R-HSA-6807004","Negative regulation of MET activity",2,87,21,11092,12.1423097974822,0.0115932731604071,0.0359618787054195,"PTPN1;HGF"]
["R-HSA-2029482","Regulation of actin dynamics for phagocytic cup formation",3,87,61,11092,6.27020915771622,0.0120922041496872,0.037363021415635,"MAPK3;MAPK1;CDC42"]
["R-HSA-69278","Cell Cycle, Mitotic",10,87,561,11092,2.27262482840576,0.0121683628582697,0.0374520428828457,"AKT1;CCND1;CDKN1A;MAPK3;MAPK1;MYC;PRKCB;BIRC5;CCNB1;CCNE1"]
["R-HSA-1181150","Signaling by NODAL",2,87,22,11092,11.5903866248694,0.0126881591797442,0.0387503239813811,"MAPK3;MAPK1"]
["R-HSA-198753","ERK/MAPK targets",2,87,22,11092,11.5903866248694,0.0126881591797442,0.0387503239813811,"MAPK3;MAPK1"]
["R-HSA-450294","MAP kinase activation",3,87,64,11092,5.97629310344828,0.0137659095071888,0.0418801323853321,"MAPK3;MAPK1;MAPK8"]
["R-HSA-449836","Other interleukin signaling",2,87,24,11092,10.6245210727969,0.0150071907670514,0.0444595052312272,"CASP3;JAK1"]
["R-HSA-8940973","RUNX2 regulates osteoblast differentiation",2,87,24,11092,10.6245210727969,0.0150071907670514,0.0444595052312272,"MAPK3;MAPK1"]
["R-HSA-9675136","Diseases of DNA Double-Strand Break Repair",2,87,24,11092,10.6245210727969,0.0150071907670514,0.0444595052312272,"BRCA1;BRCA2"]
["R-HSA-9701192","Defective HDR through Homologous Recombination (HRR) due to BRCA1 loss-of-function",2,87,24,11092,10.6245210727969,0.0150071907670514,0.0444595052312272,"BRCA1;BRCA2"]
["R-HSA-9701193","Defective HDR through Homologous Recombination (HRR) due to PALB2 loss of function",2,87,24,11092,10.6245210727969,0.0150071907670514,0.0444595052312272,"BRCA1;BRCA2"]
["R-HSA-9704331","Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA1 binding function",2,87,24,11092,10.6245210727969,0.0150071907670514,0.0444595052312272,"BRCA1;BRCA2"]
["R-HSA-9704646","Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA2/RAD51/RAD51C binding function",2,87,24,11092,10.6245210727969,0.0150071907670514,0.0444595052312272,"BRCA1;BRCA2"]
["R-HSA-1169091","Activation of NF-kappaB in B cells",3,87,67,11092,5.70869788986104,0.0155651332416146,0.0457695925431865,"RELA;NFKBIA;PRKCB"]
["R-HSA-6802952","Signaling by BRAF and RAF1 fusions",3,87,67,11092,5.70869788986104,0.0155651332416146,0.0457695925431865,"MAPK3;MAPK1;BCL2L11"]
["R-HSA-211981","Xenobiotics",2,87,25,11092,10.1995402298851,0.0162298833213657,0.0475475470637047,"CYP1A1;AHR"]
["R-HSA-400253","Circadian Clock",3,87,70,11092,5.464039408867,0.0174909182646128,0.0506869880320003,"NCOA2;PPARA;SREBF1"]
["R-HSA-5693554","Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)",2,87,26,11092,9.80725022104332,0.0174937392322833,0.0506869880320003,"BRCA1;BRCA2"]
["R-HSA-9637690","Response of Mtb to phagocytosis",2,87,26,11092,9.80725022104332,0.0174937392322833,0.0506869880320003,"MAPK3;MAPK1"]
["R-HSA-114608","Platelet degranulation ",4,87,129,11092,3.95331016662212,0.0185149740720539,0.0528608785072252,"VEGFA;PECAM1;HGF;SPARC"]
["R-HSA-1368108","BMAL1:CLOCK,NPAS2 activates circadian gene expression",2,87,27,11092,9.44401873137505,0.0187980531513233,0.0528608785072252,"NCOA2;PPARA"]
["R-HSA-1538133","G0 and Early G1",2,87,27,11092,9.44401873137505,0.0187980531513233,0.0528608785072252,"MYC;CCNE1"]
["R-HSA-354192","Integrin signaling",2,87,27,11092,9.44401873137505,0.0187980531513233,0.0528608785072252,"AKT1;PTPN1"]
["R-HSA-380994","ATF4 activates genes in response to endoplasmic reticulum  stress",2,87,27,11092,9.44401873137505,0.0187980531513233,0.0528608785072252,"CXCL8;DDIT3"]
["R-HSA-1169408","ISG15 antiviral mechanism",3,87,72,11092,5.31226053639847,0.018845471225079,0.0528608785072252,"MAPK3;STAT1;JAK1"]
["R-HSA-1445148","Translocation of SLC2A4 (GLUT4) to the plasma membrane",3,87,72,11092,5.31226053639847,0.018845471225079,0.0528608785072252,"AKT1;PRKAG2;SLC2A4"]
["R-HSA-448424","Interleukin-17 signaling",3,87,72,11092,5.31226053639847,0.018845471225079,0.0528608785072252,"MAPK3;MAPK1;MAPK8"]
["R-HSA-909733","Interferon alpha/beta signaling",3,87,72,11092,5.31226053639847,0.018845471225079,0.0528608785072252,"STAT1;PTPN1;JAK1"]
["R-HSA-9682385","FLT3 signaling in disease",2,87,28,11092,9.10673234811166,0.0201421280390102,0.0562983154729931,"BCL2L1;CDKN1A"]
["R-HSA-5663205","Infectious disease",15,87,1088,11092,1.75773326572008,0.021268250763102,0.0591197659325646,"RELA;VEGFA;MAPK3;MAPK1;IL10;IL6;MAPK8;CTNNB1;IL1B;XRCC6;IL1A;NFE2L2;JAK1;CDC42;CD28"]
["R-HSA-186763","Downstream signal transduction",2,87,29,11092,8.7927070947285,0.0215252750803775,0.0591197659325646,"STAT3;STAT1"]
["R-HSA-380972","Energy dependent regulation of mTOR by LKB1-AMPK",2,87,29,11092,8.7927070947285,0.0215252750803775,0.0591197659325646,"PRKAG2;MTOR"]
["R-HSA-442742","CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling",2,87,29,11092,8.7927070947285,0.0215252750803775,0.0591197659325646,"MAPK3;MAPK1"]
["R-HSA-5654732","Negative regulation of FGFR3 signaling",2,87,29,11092,8.7927070947285,0.0215252750803775,0.0591197659325646,"MAPK3;MAPK1"]
["R-HSA-204998","Cell death signalling via NRAGE, NRIF and NADE",3,87,76,11092,5.03266787658802,0.0217249234027696,0.0594616415625977,"CASP3;MAPK8;BCL2L11"]
["R-HSA-525793","Myogenesis",2,87,30,11092,8.49961685823755,0.0229468136012637,0.062589412271033,"CTNNB1;CDC42"]
["R-HSA-202733","Cell surface interactions at the vascular wall",4,87,138,11092,3.69548559053806,0.0230760970564811,0.0627257483562769,"SELE;PECAM1;TNFRSF10A;BSG"]
["R-HSA-74752","Signaling by Insulin receptor",3,87,78,11092,4.90362511052166,0.0232499828336744,0.0629819740460151,"MAPK3;MAPK1;IRS1"]
["R-HSA-6806834","Signaling by MET",3,87,79,11092,4.84155390659101,0.0240338570754219,0.0648832114220434,"STAT3;PTPN1;HGF"]
["R-HSA-1474228","Degradation of the extracellular matrix",4,87,140,11092,3.64269293924466,0.0241746070955419,0.0650006806378574,"MMP2;MMP9;CASP3;BSG"]
["R-HSA-182971","EGFR downregulation",2,87,31,11092,8.22543566926214,0.0244060709853902,0.0650006806378574,"CDC42;TGFA"]
["R-HSA-1839124","FGFR1 mutant receptor activation",2,87,31,11092,8.22543566926214,0.0244060709853902,0.0650006806378574,"STAT3;STAT1"]
["R-HSA-5654733","Negative regulation of FGFR4 signaling",2,87,31,11092,8.22543566926214,0.0244060709853902,0.0650006806378574,"MAPK3;MAPK1"]
["R-HSA-1169410","Antiviral mechanism by IFN-stimulated genes",3,87,80,11092,4.78103448275862,0.024831957508625,0.0656925698639544,"MAPK3;STAT1;JAK1"]
["R-HSA-438064","Post NMDA receptor activation events",3,87,80,11092,4.78103448275862,0.024831957508625,0.0656925698639544,"MAPK3;MAPK1;PRKAG2"]
["R-HSA-68875","Mitotic Prophase",4,87,142,11092,3.59138740488911,0.0253044323692675,0.0667193533469686,"MAPK3;MAPK1;PRKCB;CCNB1"]
["R-HSA-5621481","C-type lectin receptors (CLRs)",4,87,143,11092,3.56627280765212,0.0258811428373656,0.0667387121512824,"RELA;NFKBIA;IL1B;PRKCD"]
["R-HSA-397795","G-protein beta:gamma signalling",2,87,32,11092,7.9683908045977,0.0259023825922171,0.0667387121512824,"AKT1;CDC42"]
["R-HSA-456926","Thrombin signalling through proteinase activated receptors (PARs)",2,87,32,11092,7.9683908045977,0.0259023825922171,0.0667387121512824,"MAPK3;MAPK1"]
["R-HSA-5260271","Diseases of Immune System",2,87,32,11092,7.9683908045977,0.0259023825922171,0.0667387121512824,"RELA;NFKBIA"]
["R-HSA-5602358","Diseases associated with the TLR signaling cascade",2,87,32,11092,7.9683908045977,0.0259023825922171,0.0667387121512824,"RELA;NFKBIA"]
["R-HSA-5626467","RHO GTPases activate IQGAPs",2,87,32,11092,7.9683908045977,0.0259023825922171,0.0667387121512824,"CTNNB1;CDC42"]
["R-HSA-8941326","RUNX2 regulates bone development",2,87,32,11092,7.9683908045977,0.0259023825922171,0.0667387121512824,"MAPK3;MAPK1"]
["R-HSA-388396","GPCR downstream signalling",10,87,633,11092,2.01412721759184,0.0259898889881931,0.0667467603560413,"AKT1;MAPK3;MAPK1;EDN1;PRKCD;CXCL8;PRKCB;AGTR1;CCR2;CDC42"]
["R-HSA-168928","DDX58/IFIH1-mediated induction of interferon-alpha/beta",3,87,82,11092,4.66442388561817,0.0264708097253885,0.0677618462549588,"RELA;NFKBIA;TRAF2"]
["R-HSA-416476","G alpha (q) signalling events",5,87,216,11092,2.9512558535547,0.0272682163924555,0.0688925635408699,"MAPK3;MAPK1;EDN1;PRKCD;AGTR1"]
["R-HSA-1168372","Downstream signaling events of B Cell Receptor (BCR)",3,87,83,11092,4.60822600747819,0.027311541119863,0.0688925635408699,"RELA;NFKBIA;PRKCB"]
["R-HSA-1592389","Activation of Matrix Metalloproteinases",2,87,33,11092,7.72692441657959,0.0274350916755676,0.0688925635408699,"MMP2;MMP9"]
["R-HSA-445989","TAK1-dependent IKK and NF-kB activation  ",2,87,33,11092,7.72692441657959,0.0274350916755676,0.0688925635408699,"RELA;NFKBIA"]
["R-HSA-5654726","Negative regulation of FGFR1 signaling",2,87,33,11092,7.72692441657959,0.0274350916755676,0.0688925635408699,"MAPK3;MAPK1"]
["R-HSA-5693568","Resolution of D-loop Structures through Holliday Junction Intermediates",2,87,33,11092,7.72692441657959,0.0274350916755676,0.0688925635408699,"BRCA1;BRCA2"]
["R-HSA-6802957","Oncogenic MAPK signaling",3,87,84,11092,4.55336617405583,0.0281664580399414,0.0705052794607395,"MAPK3;MAPK1;BCL2L11"]
["R-HSA-5654727","Negative regulation of FGFR2 signaling",2,87,34,11092,7.49966193373901,0.0290035493030169,0.0717722347449205,"MAPK3;MAPK1"]
["R-HSA-5693537","Resolution of D-Loop Structures",2,87,34,11092,7.49966193373901,0.0290035493030169,0.0717722347449205,"BRCA1;BRCA2"]
["R-HSA-9675135","Diseases of DNA repair",2,87,34,11092,7.49966193373901,0.0290035493030169,0.0717722347449205,"BRCA1;BRCA2"]
["R-HSA-216083","Integrin cell surface interactions",3,87,85,11092,4.49979716024341,0.0290355437653282,0.0717722347449205,"VCAM1;PECAM1;BSG"]
["R-HSA-211859","Biological oxidations",5,87,222,11092,2.87149218183701,0.0302031188564277,0.0744257539421629,"PTGS1;NCOA2;CYP1A1;CYP1B1;AHR"]
["R-HSA-2559585","Oncogene Induced Senescence",2,87,35,11092,7.28538587848933,0.0306071142760353,0.0751870415911302,"MAPK3;MAPK1"]
["R-HSA-5628897","TP53 Regulates Metabolic Genes",3,87,87,11092,4.39635354736425,0.0308161422443505,0.0754661563940597,"AKT1;PRKAG2;MTOR"]
["R-HSA-9679191","Potential therapeutics for SARS",3,87,88,11092,4.34639498432602,0.0317276092103801,0.0774584533500329,"VEGFA;NFE2L2;JAK1"]
["R-HSA-1222556","ROS and RNS production in phagocytes",2,87,36,11092,7.08301404853129,0.0322451530508825,0.0779997433126852,"NOS3;MPO"]
["R-HSA-6802948","Signaling by high-kinase activity BRAF mutants",2,87,36,11092,7.08301404853129,0.0322451530508825,0.0779997433126852,"MAPK3;MAPK1"]
["R-HSA-6804757","Regulation of TP53 Degradation",2,87,36,11092,7.08301404853129,0.0322451530508825,0.0779997433126852,"AKT1;MTOR"]
["R-HSA-170834","Signaling by TGF-beta Receptor Complex",3,87,89,11092,4.29755908562573,0.0326531535110528,0.0782686194764931,"MAPK3;MAPK1;MYC"]
["R-HSA-3371556","Cellular response to heat stress",3,87,89,11092,4.29755908562573,0.0326531535110528,0.0782686194764931,"MAPK3;MAPK1;MTOR"]
["R-HSA-5687128","MAPK6/MAPK4 signaling",3,87,89,11092,4.29755908562573,0.0326531535110528,0.0782686194764931,"FOXO1;MYC;CDC42"]
["R-HSA-9616222","Transcriptional regulation of granulopoiesis",3,87,90,11092,4.24980842911877,0.0335927463927172,0.0802775298992125,"STAT3;CDKN1A;MYC"]
["R-HSA-5357905","Regulation of TNFR1 signaling",2,87,37,11092,6.89158123640882,0.0339170396602441,0.0805657008145738,"CFLAR;TRAF2"]
["R-HSA-6806003","Regulation of TP53 Expression and Degradation",2,87,37,11092,6.89158123640882,0.0339170396602441,0.0805657008145738,"AKT1;MTOR"]
["R-HSA-6798695","Neutrophil degranulation",8,87,481,11092,2.12048653427964,0.0346333921744328,0.0820209976346598,"PLAU;MMP9;MAPK1;CAT;PRKCD;XRCC6;PECAM1;MPO"]
["R-HSA-2682334","EPH-Ephrin signaling",3,87,92,11092,4.15742128935532,0.0355139516718308,0.0833642754667539,"MMP2;MMP9;CDC42"]
["R-HSA-5655302","Signaling by FGFR1 in disease",2,87,38,11092,6.7102238354507,0.0356221556356041,0.0833642754667539,"STAT3;STAT1"]
["R-HSA-8950505","Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation",2,87,38,11092,6.7102238354507,0.0356221556356041,0.0833642754667539,"IL10;CDC42"]
["R-HSA-9607240","FLT3 Signaling",2,87,38,11092,6.7102238354507,0.0356221556356041,0.0833642754667539,"AKT1;BCL2L11"]
["R-HSA-442755","Activation of NMDA receptors and postsynaptic events",3,87,93,11092,4.11271783463107,0.036495495497735,0.0843745953042598,"MAPK3;MAPK1;PRKAG2"]
["R-HSA-5633007","Regulation of TP53 Activity",4,87,160,11092,3.18735632183908,0.0369060001339467,0.0843745953042598,"AKT1;BRCA1;PRKAG2;MTOR"]
["R-HSA-111996","Ca-dependent events",2,87,39,11092,6.53816681402888,0.0373598899303476,0.0843745953042598,"MAPK1;PRKCD"]
["R-HSA-390471","Association of TriC/CCT with target proteins during biosynthesis",2,87,39,11092,6.53816681402888,0.0373598899303476,0.0843745953042598,"STAT3;CCNE1"]
["R-HSA-5693616","Presynaptic phase of homologous DNA pairing and strand exchange",2,87,39,11092,6.53816681402888,0.0373598899303476,0.0843745953042598,"BRCA1;BRCA2"]
["R-HSA-76009","Platelet Aggregation (Plug Formation)",2,87,39,11092,6.53816681402888,0.0373598899303476,0.0843745953042598,"AKT1;PTPN1"]
["R-HSA-381119","Unfolded Protein Response (UPR)",3,87,94,11092,4.06896551724138,0.0374909508587681,0.0843745953042598,"CXCL8;DDIT3;EIF2S1"]
["R-HSA-1592230","Mitochondrial biogenesis",3,87,95,11092,4.02613430127042,0.0385002782287342,0.0843745953042598,"NCOA2;PRKAG2;PPARA"]
["R-HSA-114516","Disinhibition of SNARE formation",1,87,5,11092,25.4988505747126,0.0386139108724931,0.0843745953042598,"PRKCB"]
["R-HSA-187024","NGF-independant TRKA activation",1,87,5,11092,25.4988505747126,0.0386139108724931,0.0843745953042598,"NTRK1"]
["R-HSA-187706","Signalling to p38 via RIT and RIN",1,87,5,11092,25.4988505747126,0.0386139108724931,0.0843745953042598,"NTRK1"]
["R-HSA-203641","NOSTRIN mediated eNOS trafficking",1,87,5,11092,25.4988505747126,0.0386139108724931,0.0843745953042598,"NOS3"]
["R-HSA-3134973","LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production",1,87,5,11092,25.4988505747126,0.0386139108724931,0.0843745953042598,"CTNNB1"]
["R-HSA-69478","G2/M DNA replication checkpoint",1,87,5,11092,25.4988505747126,0.0386139108724931,0.0843745953042598,"CCNB1"]
["R-HSA-74713","IRS activation",1,87,5,11092,25.4988505747126,0.0386139108724931,0.0843745953042598,"IRS1"]
["R-HSA-8865999","MET activates PTPN11",1,87,5,11092,25.4988505747126,0.0386139108724931,0.0843745953042598,"HGF"]
["R-HSA-8875513","MET interacts with TNS proteins",1,87,5,11092,25.4988505747126,0.0386139108724931,0.0843745953042598,"HGF"]
["R-HSA-8952158","RUNX3 regulates BCL2L11 (BIM) transcription",1,87,5,11092,25.4988505747126,0.0386139108724931,0.0843745953042598,"BCL2L11"]
["R-HSA-9022707","MECP2 regulates transcription factors",1,87,5,11092,25.4988505747126,0.0386139108724931,0.0843745953042598,"PPARG"]
["R-HSA-9031525","NR1H2 & NR1H3 regulate gene expression to limit cholesterol uptake ",1,87,5,11092,25.4988505747126,0.0386139108724931,0.0843745953042598,"NR1H3"]
["R-HSA-9031528","NR1H2 & NR1H3 regulate gene expression linked to triglyceride lipolysis in adipose",1,87,5,11092,25.4988505747126,0.0386139108724931,0.0843745953042598,"NR1H3"]
["R-HSA-9632974","NR1H2 & NR1H3 regulate gene expression linked to gluconeogenesis ",1,87,5,11092,25.4988505747126,0.0386139108724931,0.0843745953042598,"NR1H3"]
["R-HSA-9693928","Defective RIPK1-mediated regulated necrosis",1,87,5,11092,25.4988505747126,0.0386139108724931,0.0843745953042598,"TRAF2"]
["R-HSA-9754119","Drug-mediated inhibition of CDK4/CDK6 activity",1,87,5,11092,25.4988505747126,0.0386139108724931,0.0843745953042598,"CCND1"]
["R-HSA-5654741","Signaling by FGFR3",2,87,40,11092,6.37471264367816,0.0391296388435865,0.0850317151793321,"MAPK3;MAPK1"]
["R-HSA-5674135","MAP2K and MAPK activation",2,87,40,11092,6.37471264367816,0.0391296388435865,0.0850317151793321,"MAPK3;MAPK1"]
["R-HSA-186712","Regulation of beta-cell development",2,87,41,11092,6.21923184749089,0.040930805944702,0.0884597472739326,"AKT1;FOXO1"]
["R-HSA-5654743","Signaling by FGFR4",2,87,41,11092,6.21923184749089,0.040930805944702,0.0884597472739326,"MAPK3;MAPK1"]
["R-HSA-5693532","DNA Double-Strand Break Repair",4,87,167,11092,3.05375455984583,0.0421238132209305,0.0907900170511063,"MAPK8;BRCA1;XRCC6;BRCA2"]
["R-HSA-3769402","Deactivation of the beta-catenin transactivating complex",2,87,42,11092,6.07115489874111,0.042762801998598,0.0916676866690813,"AKT1;CTNNB1"]
["R-HSA-5693579","Homologous DNA Pairing and Strand Exchange",2,87,42,11092,6.07115489874111,0.042762801998598,0.0916676866690813,"BRCA1;BRCA2"]
["R-HSA-5675221","Negative regulation of MAPK pathway",2,87,43,11092,5.92996524993317,0.0446250448916577,0.0951439636369305,"MAPK3;MAPK1"]
["R-HSA-9656223","Signaling by RAF1 mutants",2,87,43,11092,5.92996524993317,0.0446250448916577,0.0951439636369305,"MAPK3;MAPK1"]
["R-HSA-173623","Classical antibody-mediated complement activation",1,87,6,11092,21.2490421455939,0.0461579344815929,0.0955783407720942,"CRP"]
["R-HSA-176417","Phosphorylation of Emi1",1,87,6,11092,21.2490421455939,0.0461579344815929,0.0955783407720942,"CCNB1"]
["R-HSA-187015","Activation of TRKA receptors",1,87,6,11092,21.2490421455939,0.0461579344815929,0.0955783407720942,"NTRK1"]
["R-HSA-205025","NADE modulates death signalling",1,87,6,11092,21.2490421455939,0.0461579344815929,0.0955783407720942,"CASP3"]
["R-HSA-2142770","Synthesis of 15-eicosatetraenoic acid derivatives",1,87,6,11092,21.2490421455939,0.0461579344815929,0.0955783407720942,"PTGS2"]
["R-HSA-433692","Proton-coupled monocarboxylate transport",1,87,6,11092,21.2490421455939,0.0461579344815929,0.0955783407720942,"BSG"]
["R-HSA-6806942","MET Receptor Activation",1,87,6,11092,21.2490421455939,0.0461579344815929,0.0955783407720942,"HGF"]
["R-HSA-8851907","MET activates PI3K/AKT signaling",1,87,6,11092,21.2490421455939,0.0461579344815929,0.0955783407720942,"HGF"]
["R-HSA-9018679","Biosynthesis of EPA-derived SPMs",1,87,6,11092,21.2490421455939,0.0461579344815929,0.0955783407720942,"PTGS2"]
["R-HSA-9603381","Activated NTRK3 signals through PI3K",1,87,6,11092,21.2490421455939,0.0461579344815929,0.0955783407720942,"IRS1"]
["R-HSA-9634635","Estrogen-stimulated signaling through PRKCZ",1,87,6,11092,21.2490421455939,0.0461579344815929,0.0955783407720942,"MAPK1"]
["R-HSA-372790","Signaling by GPCR",10,87,708,11092,1.8007662835249,0.0498603705771283,0.102975334533965,"AKT1;MAPK3;MAPK1;EDN1;PRKCD;CXCL8;PRKCB;AGTR1;CCR2;CDC42"]
["R-HSA-75893","TNF signaling",2,87,46,11092,5.5432283858071,0.0503875387564413,0.103793081136315,"CFLAR;TRAF2"]
["R-HSA-6802946","Signaling by moderate kinase activity BRAF mutants",2,87,47,11092,5.42528735632184,0.0523650877469948,0.106345757275691,"MAPK3;MAPK1"]
["R-HSA-6802949","Signaling by RAS mutants",2,87,47,11092,5.42528735632184,0.0523650877469948,0.106345757275691,"MAPK3;MAPK1"]
["R-HSA-6802955","Paradoxical activation of RAF signaling by kinase inactive BRAF",2,87,47,11092,5.42528735632184,0.0523650877469948,0.106345757275691,"MAPK3;MAPK1"]
["R-HSA-9024446","NR1H2 and NR1H3-mediated signaling",2,87,47,11092,5.42528735632184,0.0523650877469948,0.106345757275691,"SREBF1;NR1H3"]
["R-HSA-9649948","Signaling downstream of RAS mutants",2,87,47,11092,5.42528735632184,0.0523650877469948,0.106345757275691,"MAPK3;MAPK1"]
["R-HSA-163685","Integration of energy metabolism",3,87,108,11092,3.54150702426564,0.0528624385767882,0.106345757275691,"PRKAG2;ADIPOR1;ADIPOR2"]
["R-HSA-111457","Release of apoptotic factors from the mitochondria",1,87,7,11092,18.2134646962233,0.053643435085968,0.106345757275691,"BAX"]
["R-HSA-112412","SOS-mediated signalling",1,87,7,11092,18.2134646962233,0.053643435085968,0.106345757275691,"IRS1"]
["R-HSA-170984","ARMS-mediated activation",1,87,7,11092,18.2134646962233,0.053643435085968,0.106345757275691,"NTRK1"]
["R-HSA-2980767","Activation of NIMA Kinases NEK9, NEK6, NEK7",1,87,7,11092,18.2134646962233,0.053643435085968,0.106345757275691,"CCNB1"]
["R-HSA-3134963","DEx/H-box helicases activate type I IFN and inflammatory cytokines production ",1,87,7,11092,18.2134646962233,0.053643435085968,0.106345757275691,"RELA"]
["R-HSA-8937144","Aryl hydrocarbon receptor signalling",1,87,7,11092,18.2134646962233,0.053643435085968,0.106345757275691,"AHR"]
["R-HSA-8939246","RUNX1 regulates transcription of genes involved in differentiation of myeloid cells",1,87,7,11092,18.2134646962233,0.053643435085968,0.106345757275691,"PRKCB"]
["R-HSA-8941855","RUNX3 regulates CDKN1A transcription",1,87,7,11092,18.2134646962233,0.053643435085968,0.106345757275691,"CDKN1A"]
["R-HSA-9652817","Signaling by MAPK mutants",1,87,7,11092,18.2134646962233,0.053643435085968,0.106345757275691,"MAPK1"]
["R-HSA-418597","G alpha (z) signalling events",2,87,48,11092,5.31226053639847,0.0543700772878335,0.107516827836691,"PRKCD;PRKCB"]
["R-HSA-983705","Signaling by the B Cell Receptor (BCR)",3,87,112,11092,3.41502463054187,0.0577339064789286,0.113884089837488,"RELA;NFKBIA;PRKCB"]
["R-HSA-1227986","Signaling by ERBB2",2,87,50,11092,5.09977011494253,0.0584602210387997,0.114177863806643,"AKT1;PRKCD"]
["R-HSA-177929","Signaling by EGFR",2,87,50,11092,5.09977011494253,0.0584602210387997,0.114177863806643,"CDC42;TGFA"]
["R-HSA-373752","Netrin-1 signaling",2,87,50,11092,5.09977011494253,0.0584602210387997,0.114177863806643,"MAPK8;CDC42"]
["R-HSA-5654736","Signaling by FGFR1",2,87,50,11092,5.09977011494253,0.0584602210387997,0.114177863806643,"MAPK3;MAPK1"]
["R-HSA-112043","PLC beta mediated events",2,87,51,11092,4.99977462249268,0.0605443132454575,0.116402533493911,"MAPK1;PRKCD"]
["R-HSA-3928665","EPH-ephrin mediated repulsion of cells",2,87,51,11092,4.99977462249268,0.0605443132454575,0.116402533493911,"MMP2;MMP9"]
["R-HSA-194313","VEGF ligand-receptor interactions",1,87,8,11092,15.9367816091954,0.0610708614411797,0.116402533493911,"VEGFA"]
["R-HSA-195399","VEGF binds to VEGFR leading to receptor dimerization",1,87,8,11092,15.9367816091954,0.0610708614411797,0.116402533493911,"VEGFA"]
["R-HSA-428543","Inactivation of CDC42 and RAC1",1,87,8,11092,15.9367816091954,0.0610708614411797,0.116402533493911,"CDC42"]
["R-HSA-450520","HuR (ELAVL1) binds and stabilizes mRNA",1,87,8,11092,15.9367816091954,0.0610708614411797,0.116402533493911,"PRKCD"]
["R-HSA-5638302","Signaling by Overexpressed Wild-Type EGFR in Cancer",1,87,8,11092,15.9367816091954,0.0610708614411797,0.116402533493911,"TGFA"]
["R-HSA-5638303","Inhibition of Signaling by Overexpressed EGFR",1,87,8,11092,15.9367816091954,0.0610708614411797,0.116402533493911,"TGFA"]
["R-HSA-72731","Recycling of eIF2:GDP",1,87,8,11092,15.9367816091954,0.0610708614411797,0.116402533493911,"EIF2S1"]
["R-HSA-8941332","RUNX2 regulates genes involved in cell migration",1,87,8,11092,15.9367816091954,0.0610708614411797,0.116402533493911,"AKT1"]
["R-HSA-196854","Metabolism of vitamins and cofactors",4,87,190,11092,2.68408953418028,0.0620627255095531,0.118008692014559,"PTGS2;AKT1;NOS3;CD320"]
["R-HSA-2980766","Nuclear Envelope Breakdown",2,87,52,11092,4.90362511052166,0.06265372185885,0.118846748178298,"PRKCB;CCNB1"]
["R-HSA-9006936","Signaling by TGFB family members",3,87,118,11092,3.24137931034483,0.0654253928244066,0.123807382115085,"MAPK3;MAPK1;MYC"]
["R-HSA-113507","E2F-enabled inhibition of pre-replication complex formation",1,87,9,11092,14.1660280970626,0.0684406589018993,0.12738014397977,"CCNB1"]
["R-HSA-212718","EGFR interacts with phospholipase C-gamma",1,87,9,11092,14.1660280970626,0.0684406589018993,0.12738014397977,"TGFA"]
["R-HSA-2142688","Synthesis of 5-eicosatetraenoic acids",1,87,9,11092,14.1660280970626,0.0684406589018993,0.12738014397977,"PON1"]
["R-HSA-8849469","PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1",1,87,9,11092,14.1660280970626,0.0684406589018993,0.12738014397977,"AKT1"]
["R-HSA-9020933","Interleukin-23 signaling",1,87,9,11092,14.1660280970626,0.0684406589018993,0.12738014397977,"STAT3"]
["R-HSA-9613354","Lipophagy",1,87,9,11092,14.1660280970626,0.0684406589018993,0.12738014397977,"PRKAG2"]
["R-HSA-9623433","NR1H2 & NR1H3 regulate gene expression to control bile acid homeostasis",1,87,9,11092,14.1660280970626,0.0684406589018993,0.12738014397977,"NR1H3"]
["R-HSA-112040","G-protein mediated events",2,87,56,11092,4.55336617405583,0.071334318846665,0.132143902125789,"MAPK1;PRKCD"]
["R-HSA-2151201","Transcriptional activation of mitochondrial biogenesis",2,87,56,11092,4.55336617405583,0.071334318846665,0.132143902125789,"NCOA2;PPARA"]
["R-HSA-375276","Peptide ligand-binding receptors",4,87,201,11092,2.53719906216046,0.0730907040817862,0.135081184412834,"EDN1;CXCL8;AGTR1;CCR2"]
["R-HSA-8932339","ROS sensing by NFE2L2",2,87,57,11092,4.47348255696713,0.0735627132311444,0.135636611109173,"PRKCD;NFE2L2"]
["R-HSA-381426","Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)",3,87,125,11092,3.05986206896552,0.074962482797291,0.136214611243789,"MMP2;IL6;PAPPA"]
["R-HSA-2151209","Activation of PPARGC1A (PGC-1alpha) by phosphorylation",1,87,10,11092,12.7494252873563,0.0757532694473777,0.136214611243789,"PRKAG2"]
["R-HSA-2465910","MASTL Facilitates Mitotic Progression",1,87,10,11092,12.7494252873563,0.0757532694473777,0.136214611243789,"CCNB1"]
["R-HSA-381183","ATF6 (ATF6-alpha) activates chaperone genes",1,87,10,11092,12.7494252873563,0.0757532694473777,0.136214611243789,"DDIT3"]
["R-HSA-8875656","MET receptor recycling",1,87,10,11092,12.7494252873563,0.0757532694473777,0.136214611243789,"HGF"]
["R-HSA-8876493","InlA-mediated entry of Listeria monocytogenes into host cells",1,87,10,11092,12.7494252873563,0.0757532694473777,0.136214611243789,"CTNNB1"]
["R-HSA-8951936","RUNX3 regulates p14-ARF",1,87,10,11092,12.7494252873563,0.0757532694473777,0.136214611243789,"CCND1"]
["R-HSA-9617629","Regulation of FOXO transcriptional activity by acetylation",1,87,10,11092,12.7494252873563,0.0757532694473777,0.136214611243789,"FOXO1"]
["R-HSA-9701898","STAT3 nuclear events downstream of ALK signaling",1,87,10,11092,12.7494252873563,0.0757532694473777,0.136214611243789,"STAT3"]
["R-HSA-9706019","RHOBTB3 ATPase cycle",1,87,10,11092,12.7494252873563,0.0757532694473777,0.136214611243789,"CCNE1"]
["R-HSA-1280218","Adaptive Immune System",10,87,765,11092,1.66659154083089,0.0757704537892123,0.136214611243789,"RELA;AKT1;NFKBIA;XDH;VCAM1;PRKCB;CD80;MTOR;CDC42;CD28"]
["R-HSA-112314","Neurotransmitter receptors and postsynaptic signal transmission",4,87,205,11092,2.48769273899636,0.0773340236007511,0.138710232807696,"MAPK3;MAPK1;PRKCB;PRKAG2"]
["R-HSA-2559580","Oxidative Stress Induced Senescence",3,87,127,11092,3.01167526472984,0.0777952936812323,0.139112650953581,"MAPK3;MAPK1;MAPK8"]
["R-HSA-193648","NRAGE signals death through JNK",2,87,59,11092,4.32183908045977,0.0780859886515677,0.139112650953581,"MAPK8;BCL2L11"]
["R-HSA-380108","Chemokine receptors bind chemokines",2,87,59,11092,4.32183908045977,0.0780859886515677,0.139112650953581,"CXCL8;CCR2"]
["R-HSA-69620","Cell Cycle Checkpoints",5,87,294,11092,2.16826960669325,0.0809830681975494,0.143949678526431,"CDKN1A;BRCA1;BIRC5;CCNB1;CCNE1"]
["R-HSA-198725","Nuclear Events (kinase and transcription factor activation)",2,87,61,11092,4.18013943847748,0.082694758109245,0.144626042246738,"MAPK3;MAPK1"]
["R-HSA-1234158","Regulation of gene expression by Hypoxia-inducible Factor",1,87,11,11092,11.5903866248694,0.0830091317067242,0.144626042246738,"VEGFA"]
["R-HSA-164843","2-LTR circle formation",1,87,11,11092,11.5903866248694,0.0830091317067242,0.144626042246738,"XRCC6"]
["R-HSA-193692","Regulated proteolysis of p75NTR",1,87,11,11092,11.5903866248694,0.0830091317067242,0.144626042246738,"RELA"]
["R-HSA-2514853","Condensation of Prometaphase Chromosomes",1,87,11,11092,11.5903866248694,0.0830091317067242,0.144626042246738,"CCNB1"]
["R-HSA-376172","DSCAM interactions",1,87,11,11092,11.5903866248694,0.0830091317067242,0.144626042246738,"MAPK8"]
["R-HSA-5625970","RHO GTPases activate KTN1",1,87,11,11092,11.5903866248694,0.0830091317067242,0.144626042246738,"CDC42"]
["R-HSA-8851805","MET activates RAS signaling",1,87,11,11092,11.5903866248694,0.0830091317067242,0.144626042246738,"HGF"]
["R-HSA-8875555","MET activates RAP1 and RAC1",1,87,11,11092,11.5903866248694,0.0830091317067242,0.144626042246738,"HGF"]
["R-HSA-8986944","Transcriptional Regulation by MECP2",2,87,62,11092,4.11271783463107,0.0850300421742778,0.147821457933744,"PPARG;PTPN1"]
["R-HSA-1226099","Signaling by FGFR in disease",2,87,63,11092,4.04743659916074,0.0873853182673335,0.151251174506479,"STAT3;STAT1"]
["R-HSA-375165","NCAM signaling for neurite out-growth",2,87,63,11092,4.04743659916074,0.0873853182673335,0.151251174506479,"MAPK3;MAPK1"]
["R-HSA-1442490","Collagen degradation",2,87,64,11092,3.98419540229885,0.0897601379047576,0.152794575285537,"MMP2;MMP9"]
["R-HSA-210990","PECAM1 interactions",1,87,12,11092,10.6245210727969,0.0902086809840023,0.152794575285537,"PECAM1"]
["R-HSA-264870","Caspase-mediated cleavage of cytoskeletal proteins",1,87,12,11092,10.6245210727969,0.0902086809840023,0.152794575285537,"CASP3"]
["R-HSA-381033","ATF6 (ATF6-alpha) activates chaperones",1,87,12,11092,10.6245210727969,0.0902086809840023,0.152794575285537,"DDIT3"]
["R-HSA-6803211","TP53 Regulates Transcription of Death Receptors and Ligands",1,87,12,11092,10.6245210727969,0.0902086809840023,0.152794575285537,"TNFRSF10A"]
["R-HSA-8851680","Butyrophilin (BTN) family interactions",1,87,12,11092,10.6245210727969,0.0902086809840023,0.152794575285537,"XDH"]
["R-HSA-8866427","VLDLR internalisation and degradation",1,87,12,11092,10.6245210727969,0.0902086809840023,0.152794575285537,"NR1H3"]
["R-HSA-9020558","Interleukin-2 signaling",1,87,12,11092,10.6245210727969,0.0902086809840023,0.152794575285537,"JAK1"]
["R-HSA-9664420","Killing mechanisms",1,87,12,11092,10.6245210727969,0.0902086809840023,0.152794575285537,"MAPK8"]
["R-HSA-9673324","WNT5:FZD7-mediated leishmania damping",1,87,12,11092,10.6245210727969,0.0902086809840023,0.152794575285537,"MAPK8"]
["R-HSA-9707587","Regulation of HMOX1 expression and activity",2,87,65,11092,3.92290008841733,0.0921540582614674,0.155756111292352,"PRKCD;NFE2L2"]
["R-HSA-69563","p53-Dependent G1 DNA Damage Response",2,87,66,11092,3.86346220828979,0.0945666421114815,0.159153646617408,"CDKN1A;CCNE1"]
["R-HSA-69580","p53-Dependent G1/S DNA damage checkpoint",2,87,66,11092,3.86346220828979,0.0945666421114815,0.159153646617408,"CDKN1A;CCNE1"]
["R-HSA-5685942","HDR through Homologous Recombination (HRR)",2,87,67,11092,3.80579859324069,0.0969974577690159,0.160763482845427,"BRCA1;BRCA2"]
["R-HSA-1358803","Downregulation of ERBB2:ERBB3 signaling",1,87,13,11092,9.80725022104332,0.0973523492831346,0.160763482845427,"AKT1"]
["R-HSA-140342","Apoptosis induced DNA fragmentation",1,87,13,11092,9.80725022104332,0.0973523492831346,0.160763482845427,"CASP3"]
["R-HSA-162592","Integration of provirus",1,87,13,11092,9.80725022104332,0.0973523492831346,0.160763482845427,"XRCC6"]
["R-HSA-179812","GRB2 events in EGFR signaling",1,87,13,11092,9.80725022104332,0.0973523492831346,0.160763482845427,"TGFA"]
["R-HSA-2892247","POU5F1 (OCT4), SOX2, NANOG activate genes related to proliferation",1,87,13,11092,9.80725022104332,0.0973523492831346,0.160763482845427,"STAT3"]
["R-HSA-3270619","IRF3-mediated induction of type I IFN",1,87,13,11092,9.80725022104332,0.0973523492831346,0.160763482845427,"XRCC6"]
["R-HSA-5357786","TNFR1-induced proapoptotic signaling",1,87,13,11092,9.80725022104332,0.0973523492831346,0.160763482845427,"TRAF2"]
["R-HSA-75035","Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex",1,87,13,11092,9.80725022104332,0.0973523492831346,0.160763482845427,"CCNB1"]
["R-HSA-69615","G1/S DNA Damage Checkpoints",2,87,68,11092,3.74983096686951,0.0994460790301436,0.163878851068424,"CDKN1A;CCNE1"]
["R-HSA-3371453","Regulation of HSF1-mediated heat shock response",2,87,69,11092,3.69548559053806,0.101912085115012,0.167245766236461,"MAPK3;MAPK1"]
["R-HSA-5693571","Nonhomologous End-Joining (NHEJ)",2,87,69,11092,3.69548559053806,0.101912085115012,0.167245766236461,"BRCA1;XRCC6"]
["R-HSA-166786","Creation of C4 and C2 activators",1,87,14,11092,9.10673234811166,0.104440565332631,0.16859691260839,"CRP"]
["R-HSA-177504","Retrograde neurotrophin signalling",1,87,14,11092,9.10673234811166,0.104440565332631,0.16859691260839,"NTRK1"]
["R-HSA-180336","SHC1 events in EGFR signaling",1,87,14,11092,9.10673234811166,0.104440565332631,0.16859691260839,"TGFA"]
["R-HSA-200425","Carnitine metabolism",1,87,14,11092,9.10673234811166,0.104440565332631,0.16859691260839,"PRKAG2"]
["R-HSA-3296469","Defects in cobalamin (B12) metabolism",1,87,14,11092,9.10673234811166,0.104440565332631,0.16859691260839,"CD320"]
["R-HSA-418885","DCC mediated attractive signaling",1,87,14,11092,9.10673234811166,0.104440565332631,0.16859691260839,"CDC42"]
["R-HSA-6803205","TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain",1,87,14,11092,9.10673234811166,0.104440565332631,0.16859691260839,"BIRC5"]
["R-HSA-6804759","Regulation of TP53 Activity through Association with Co-factors",1,87,14,11092,9.10673234811166,0.104440565332631,0.16859691260839,"AKT1"]
["R-HSA-193807","Synthesis of bile acids and bile salts via 27-hydroxycholesterol",1,87,15,11092,8.49961685823755,0.111473754610124,0.177059718667887,"NCOA2"]
["R-HSA-4839743","Signaling by CTNNB1 phospho-site mutants",1,87,15,11092,8.49961685823755,0.111473754610124,0.177059718667887,"CTNNB1"]
["R-HSA-5099900","WNT5A-dependent internalization of FZD4",1,87,15,11092,8.49961685823755,0.111473754610124,0.177059718667887,"PRKCB"]
["R-HSA-5339716","Signaling by GSK3beta mutants",1,87,15,11092,8.49961685823755,0.111473754610124,0.177059718667887,"CTNNB1"]
["R-HSA-5358747","CTNNB1 S33 mutants aren't phosphorylated",1,87,15,11092,8.49961685823755,0.111473754610124,0.177059718667887,"CTNNB1"]
["R-HSA-5358749","CTNNB1 S37 mutants aren't phosphorylated",1,87,15,11092,8.49961685823755,0.111473754610124,0.177059718667887,"CTNNB1"]
["R-HSA-5358751","CTNNB1 S45 mutants aren't phosphorylated",1,87,15,11092,8.49961685823755,0.111473754610124,0.177059718667887,"CTNNB1"]
["R-HSA-5358752","CTNNB1 T41 mutants aren't phosphorylated",1,87,15,11092,8.49961685823755,0.111473754610124,0.177059718667887,"CTNNB1"]
["R-HSA-5654738","Signaling by FGFR2",2,87,73,11092,3.49299322941269,0.111941728747836,0.177446708295668,"MAPK3;MAPK1"]
["R-HSA-9716542","Signaling by Rho GTPases, Miro GTPases and RHOBTB3",9,87,723,11092,1.58706538846759,0.112611723972016,0.178151747323729,"NCOA2;MAPK3;MAPK1;CTNNB1;PRKCD;PRKCB;BIRC5;CCNE1;CDC42"]
["R-HSA-157118","Signaling by NOTCH",4,87,236,11092,2.16091954022989,0.114219623143473,0.180334774264445,"AKT1;CCND1;STAT1;MYC"]
["R-HSA-156711","Polo-like kinase mediated events",1,87,16,11092,7.9683908045977,0.118452339366729,0.185423301997729,"CCNB1"]
["R-HSA-1834941","STING mediated induction of host immune responses",1,87,16,11092,7.9683908045977,0.118452339366729,0.185423301997729,"XRCC6"]
["R-HSA-205043","NRIF signals cell death from the nucleus",1,87,16,11092,7.9683908045977,0.118452339366729,0.185423301997729,"MAPK8"]
["R-HSA-844456","The NLRP3 inflammasome",1,87,16,11092,7.9683908045977,0.118452339366729,0.185423301997729,"RELA"]
["R-HSA-8957322","Metabolism of steroids",3,87,153,11092,2.49988731124634,0.118614653363907,0.185423301997729,"NCOA2;PPARA;SREBF1"]
["R-HSA-5693565","Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks",2,87,77,11092,3.31153903567697,0.12221723898664,0.189928950959591,"MAPK8;BRCA1"]
["R-HSA-8852276","The role of GTSE1 in G2/M progression after G2 checkpoint",2,87,77,11092,3.31153903567697,0.12221723898664,0.189928950959591,"CDKN1A;CCNB1"]
["R-HSA-9635486","Infection with Mycobacterium tuberculosis",2,87,77,11092,3.31153903567697,0.12221723898664,0.189928950959591,"MAPK3;MAPK1"]
["R-HSA-9711097","Cellular response to starvation",3,87,156,11092,2.45181255526083,0.123759852269067,0.190717308217538,"DDIT3;MTOR;EIF2S1"]
["R-HSA-5693606","DNA Double Strand Break Response",2,87,78,11092,3.26908340701444,0.124821640464349,0.190717308217538,"MAPK8;BRCA1"]
["R-HSA-180292","GAB1 signalosome",1,87,17,11092,7.49966193373901,0.125376738651226,0.190717308217538,"TGFA"]
["R-HSA-196299","Beta-catenin phosphorylation cascade",1,87,17,11092,7.49966193373901,0.125376738651226,0.190717308217538,"CTNNB1"]
["R-HSA-416993","Trafficking of GluR2-containing AMPA receptors",1,87,17,11092,7.49966193373901,0.125376738651226,0.190717308217538,"PRKCB"]
["R-HSA-432142","Platelet sensitization by LDL",1,87,17,11092,7.49966193373901,0.125376738651226,0.190717308217538,"PECAM1"]
["R-HSA-450385","Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA",1,87,17,11092,7.49966193373901,0.125376738651226,0.190717308217538,"AKT1"]
["R-HSA-450604","KSRP (KHSRP) binds and destabilizes mRNA",1,87,17,11092,7.49966193373901,0.125376738651226,0.190717308217538,"AKT1"]
["R-HSA-6788467","IL-6-type cytokine receptor ligand interactions",1,87,17,11092,7.49966193373901,0.125376738651226,0.190717308217538,"JAK1"]
["R-HSA-8934593","Regulation of RUNX1 Expression and Activity",1,87,17,11092,7.49966193373901,0.125376738651226,0.190717308217538,"CCND1"]
["R-HSA-9022699","MECP2 regulates neuronal receptors and channels",1,87,17,11092,7.49966193373901,0.125376738651226,0.190717308217538,"PTPN1"]
["R-HSA-2559586","DNA Damage/Telomere Stress Induced Senescence",2,87,80,11092,3.18735632183908,0.130070467723325,0.19747742796382,"CDKN1A;CCNE1"]
["R-HSA-159418","Recycling of bile acids and salts",1,87,18,11092,7.08301404853129,0.132247368334056,0.199632954870684,"NCOA2"]
["R-HSA-5676594","TNF receptor superfamily (TNFSF) members mediating non-canonical NF-kB pathway",1,87,18,11092,7.08301404853129,0.132247368334056,0.199632954870684,"TRAF2"]
["R-HSA-74259","Purine catabolism",1,87,18,11092,7.08301404853129,0.132247368334056,0.199632954870684,"XDH"]
["R-HSA-2871837","FCERI mediated NF-kB activation",2,87,82,11092,3.10961592374544,0.135370252703793,0.203957847407047,"RELA;NFKBIA"]
["R-HSA-1362277","Transcription of E2F targets under negative control by DREAM complex",1,87,19,11092,6.7102238354507,0.139064641131143,0.207939756398363,"MYC"]
["R-HSA-197264","Nicotinamide salvaging",1,87,19,11092,6.7102238354507,0.139064641131143,0.207939756398363,"PTGS2"]
["R-HSA-2995383","Initiation of Nuclear Envelope (NE) Reformation",1,87,19,11092,6.7102238354507,0.139064641131143,0.207939756398363,"CCNB1"]
["R-HSA-9703465","Signaling by FLT3 fusion proteins",1,87,19,11092,6.7102238354507,0.139064641131143,0.207939756398363,"CDKN1A"]
["R-HSA-1430728","Metabolism",21,87,2117,11092,1.26470444513218,0.143516661574154,0.214191847745577,"PTGS1;PTGS2;NCOA2;AKT1;ODC1;XDH;PPARG;CYP1A1;NOS3;CYP1B1;AHR;PRKAG2;PPARA;PON1;SREBF1;ADIPOR1;ADIPOR2;PTGES;BSG;NR1H3;CD320"]
["R-HSA-162594","Early Phase of HIV Life Cycle",1,87,20,11092,6.37471264367816,0.145828966627538,0.215206553362655,"XRCC6"]
["R-HSA-167044","Signalling to RAS",1,87,20,11092,6.37471264367816,0.145828966627538,0.215206553362655,"NTRK1"]
["R-HSA-176412","Phosphorylation of the APC/C",1,87,20,11092,6.37471264367816,0.145828966627538,0.215206553362655,"CCNB1"]
["R-HSA-2028269","Signaling by Hippo",1,87,20,11092,6.37471264367816,0.145828966627538,0.215206553362655,"CASP3"]
["R-HSA-6803204","TP53 Regulates Transcription of Genes Involved in Cytochrome C Release",1,87,20,11092,6.37471264367816,0.145828966627538,0.215206553362655,"BAX"]
["R-HSA-8964616","G beta:gamma signalling through CDC42",1,87,20,11092,6.37471264367816,0.145828966627538,0.215206553362655,"CDC42"]
["R-HSA-912446","Meiotic recombination",2,87,86,11092,2.96498262496659,0.146111475131193,0.215221930779839,"BRCA1;BRCA2"]
["R-HSA-190236","Signaling by FGFR",2,87,87,11092,2.9309023649095,0.148824306493236,0.218810458059758,"MAPK3;MAPK1"]
["R-HSA-418346","Platelet homeostasis",2,87,88,11092,2.89759665621735,0.151547485499814,0.221394007851392,"PECAM1;NOS3"]
["R-HSA-450531","Regulation of mRNA stability by proteins that bind AU-rich elements",2,87,88,11092,2.89759665621735,0.151547485499814,0.221394007851392,"AKT1;PRKCD"]
["R-HSA-189200","Cellular hexose transport",1,87,21,11092,6.07115489874111,0.152540751300896,0.221394007851392,"SLC2A4"]
["R-HSA-196741","Cobalamin (Cbl, vitamin B12) transport and metabolism",1,87,21,11092,6.07115489874111,0.152540751300896,0.221394007851392,"CD320"]
["R-HSA-381771","Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)",1,87,21,11092,6.07115489874111,0.152540751300896,0.221394007851392,"CTNNB1"]
["R-HSA-5621575","CD209 (DC-SIGN) signaling",1,87,21,11092,6.07115489874111,0.152540751300896,0.221394007851392,"RELA"]
["R-HSA-9008059","Interleukin-37 signaling",1,87,21,11092,6.07115489874111,0.152540751300896,0.221394007851392,"STAT3"]
["R-HSA-113510","E2F mediated regulation of DNA replication",1,87,22,11092,5.79519331243469,0.15920039854476,0.227621184670517,"CCNB1"]
["R-HSA-1250196","SHC1 events in ERBB2 signaling",1,87,22,11092,5.79519331243469,0.15920039854476,0.227621184670517,"PRKCD"]
["R-HSA-164938","Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters",1,87,22,11092,5.79519331243469,0.15920039854476,0.227621184670517,"CD28"]
["R-HSA-3296482","Defects in vitamin and cofactor metabolism",1,87,22,11092,5.79519331243469,0.15920039854476,0.227621184670517,"CD320"]
["R-HSA-392154","Nitric oxide stimulates guanylate cyclase",1,87,22,11092,5.79519331243469,0.15920039854476,0.227621184670517,"NOS3"]
["R-HSA-8862803","Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models",1,87,22,11092,5.79519331243469,0.15920039854476,0.227621184670517,"BCL2L11"]
["R-HSA-8863678","Neurodegenerative Diseases",1,87,22,11092,5.79519331243469,0.15920039854476,0.227621184670517,"BCL2L11"]
["R-HSA-8876384","Listeria monocytogenes entry into host cells",1,87,22,11092,5.79519331243469,0.15920039854476,0.227621184670517,"CTNNB1"]
["R-HSA-201722","Formation of the beta-catenin:TCF transactivating complex",2,87,91,11092,2.80207149172666,0.159775893825949,0.227621184670517,"CTNNB1;MYC"]
["R-HSA-390466","Chaperonin-mediated protein folding",2,87,91,11092,2.80207149172666,0.159775893825949,0.227621184670517,"STAT3;CCNE1"]
["R-HSA-9679506","SARS-CoV Infections",3,87,176,11092,2.17319749216301,0.159996686064232,0.227621184670517,"VEGFA;NFE2L2;JAK1"]
["R-HSA-112315","Transmission across Chemical Synapses",4,87,270,11092,1.88880374627501,0.161945954884004,0.229980700741916,"MAPK3;MAPK1;PRKCB;PRKAG2"]
["R-HSA-111885","Opioid Signalling",2,87,92,11092,2.77161419290355,0.162537270318262,0.229994598965556,"MAPK1;PRKCD"]
["R-HSA-6804756","Regulation of TP53 Activity through Phosphorylation",2,87,92,11092,2.77161419290355,0.162537270318262,0.229994598965556,"BRCA1;PRKAG2"]
["R-HSA-166663","Initial triggering of complement",1,87,23,11092,5.5432283858071,0.165808308691698,0.233786759670469,"CRP"]
["R-HSA-450321","JNK (c-Jun kinases) phosphorylation and  activation mediated by activated human TAK1",1,87,23,11092,5.5432283858071,0.165808308691698,0.233786759670469,"MAPK8"]
["R-HSA-69473","G2/M DNA damage checkpoint",2,87,95,11092,2.68408953418028,0.170872828627445,0.239194068978372,"BRCA1;CCNB1"]
["R-HSA-9748784","Drug ADME",2,87,95,11092,2.68408953418028,0.170872828627445,0.239194068978372,"XDH;BSG"]
["R-HSA-166208","mTORC1-mediated signalling",1,87,24,11092,5.31226053639847,0.172364879036248,0.239194068978372,"MTOR"]
["R-HSA-174048","APC/C:Cdc20 mediated degradation of Cyclin B",1,87,24,11092,5.31226053639847,0.172364879036248,0.239194068978372,"CCNB1"]
["R-HSA-193368","Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol",1,87,24,11092,5.31226053639847,0.172364879036248,0.239194068978372,"NCOA2"]
["R-HSA-3371571","HSF1-dependent transactivation",1,87,24,11092,5.31226053639847,0.172364879036248,0.239194068978372,"MTOR"]
["R-HSA-400508","Incretin synthesis, secretion, and inactivation",1,87,24,11092,5.31226053639847,0.172364879036248,0.239194068978372,"CTNNB1"]
["R-HSA-5627123","RHO GTPases activate PAKs",1,87,24,11092,5.31226053639847,0.172364879036248,0.239194068978372,"CDC42"]
["R-HSA-9748787","Azathioprine ADME",1,87,24,11092,5.31226053639847,0.172364879036248,0.239194068978372,"XDH"]
["R-HSA-391251","Protein folding",2,87,97,11092,2.62874748192914,0.176469751620991,0.244363676254648,"STAT3;CCNE1"]
["R-HSA-1643713","Signaling by EGFR in Cancer",1,87,25,11092,5.09977011494253,0.178870503857701,0.244363676254648,"TGFA"]
["R-HSA-2029485","Role of phospholipids in phagocytosis",1,87,25,11092,5.09977011494253,0.178870503857701,0.244363676254648,"PRKCD"]
["R-HSA-210991","Basigin interactions",1,87,25,11092,5.09977011494253,0.178870503857701,0.244363676254648,"BSG"]
["R-HSA-392451","G beta:gamma signalling through PI3Kgamma",1,87,25,11092,5.09977011494253,0.178870503857701,0.244363676254648,"AKT1"]
["R-HSA-452723","Transcriptional regulation of pluripotent stem cells",1,87,25,11092,5.09977011494253,0.178870503857701,0.244363676254648,"STAT3"]
["R-HSA-69273","Cyclin A/B1/B2 associated events during G2/M transition",1,87,25,11092,5.09977011494253,0.178870503857701,0.244363676254648,"CCNB1"]
["R-HSA-9013508","NOTCH3 Intracellular Domain Regulates Transcription",1,87,25,11092,5.09977011494253,0.178870503857701,0.244363676254648,"STAT1"]
["R-HSA-9734009","Defective Intrinsic Pathway for Apoptosis",1,87,25,11092,5.09977011494253,0.178870503857701,0.244363676254648,"BCL2L11"]
["R-HSA-202424","Downstream TCR signaling",2,87,98,11092,2.6019235280319,0.179279307545598,0.244499883221669,"RELA;NFKBIA"]
["R-HSA-9633012","Response of EIF2AK4 (GCN2) to amino acid deficiency",2,87,101,11092,2.52463867076363,0.187748976285759,0.255610052051697,"DDIT3;EIF2S1"]
["R-HSA-194315","Signaling by Rho GTPases",8,87,707,11092,1.44265066900779,0.189278356727718,0.25724945046671,"NCOA2;MAPK3;MAPK1;CTNNB1;PRKCD;PRKCB;BIRC5;CDC42"]
["R-HSA-114508","Effects of PIP2 hydrolysis",1,87,27,11092,4.72200936568753,0.191730479107771,0.258803428283698,"PRKCD"]
["R-HSA-191273","Cholesterol biosynthesis",1,87,27,11092,4.72200936568753,0.191730479107771,0.258803428283698,"SREBF1"]
["R-HSA-912526","Interleukin receptor SHC signaling",1,87,27,11092,4.72200936568753,0.191730479107771,0.258803428283698,"JAK1"]
["R-HSA-9648002","RAS processing",1,87,27,11092,4.72200936568753,0.191730479107771,0.258803428283698,"BCL2L1"]
["R-HSA-9645723","Diseases of programmed cell death",2,87,103,11092,2.47561656065171,0.193426852631477,0.260648450479554,"BCL2L11;TRAF2"]
["R-HSA-69205","G1/S-Specific Transcription",1,87,28,11092,4.55336617405583,0.198085603221429,0.266472299571685,"CCNE1"]
["R-HSA-8856825","Cargo recognition for clathrin-mediated endocytosis",2,87,106,11092,2.40555194101063,0.201985508142269,0.271257278337071,"AGTR1;TGFA"]
["R-HSA-164952","The role of Nef in HIV-1 replication and disease pathogenesis",1,87,29,11092,4.39635354736425,0.204391329226467,0.273097198341445,"CD28"]
["R-HSA-8863795","Downregulation of ERBB2 signaling",1,87,29,11092,4.39635354736425,0.204391329226467,0.273097198341445,"AKT1"]
["R-HSA-9619483","Activation of AMPK downstream of NMDARs",1,87,29,11092,4.39635354736425,0.204391329226467,0.273097198341445,"PRKAG2"]
["R-HSA-5688426","Deubiquitination",4,87,298,11092,1.71133225333642,0.205844172781347,0.274574604839874,"NFKBIA;MYC;BRCA1;TRAF2"]
["R-HSA-5357956","TNFR1-induced NFkappaB signaling pathway",1,87,30,11092,4.24980842911877,0.210648036661819,0.279099827469847,"TRAF2"]
["R-HSA-6804758","Regulation of TP53 Activity through Acetylation",1,87,30,11092,4.24980842911877,0.210648036661819,0.279099827469847,"AKT1"]
["R-HSA-8874081","MET activates PTK2 signaling",1,87,30,11092,4.24980842911877,0.210648036661819,0.279099827469847,"HGF"]
["R-HSA-933541","TRAF6 mediated IRF7 activation",1,87,30,11092,4.24980842911877,0.210648036661819,0.279099827469847,"TRAF2"]
["R-HSA-196807","Nicotinate metabolism",1,87,31,11092,4.11271783463107,0.216856102184366,0.284938831939923,"PTGS2"]
["R-HSA-399719","Trafficking of AMPA receptors",1,87,31,11092,4.11271783463107,0.216856102184366,0.284938831939923,"PRKCB"]
["R-HSA-399721","Glutamate binding, activation of AMPA receptors and synaptic plasticity",1,87,31,11092,4.11271783463107,0.216856102184366,0.284938831939923,"PRKCB"]
["R-HSA-4641262","Disassembly of the destruction complex and recruitment of AXIN to the membrane",1,87,31,11092,4.11271783463107,0.216856102184366,0.284938831939923,"CTNNB1"]
["R-HSA-70268","Pyruvate metabolism",1,87,31,11092,4.11271783463107,0.216856102184366,0.284938831939923,"BSG"]
["R-HSA-1251985","Nuclear signaling by ERBB4",1,87,32,11092,3.98419540229885,0.223015899590565,0.29254656148613,"SPARC"]
["R-HSA-418990","Adherens junctions interactions",1,87,33,11092,3.86346220828979,0.229127799837909,0.299076055564003,"CTNNB1"]
["R-HSA-5694530","Cargo concentration in the ER",1,87,33,11092,3.86346220828979,0.229127799837909,0.299076055564003,"TGFA"]
["R-HSA-8964043","Plasma lipoprotein clearance",1,87,33,11092,3.86346220828979,0.229127799837909,0.299076055564003,"NR1H3"]
["R-HSA-68886","M Phase",5,87,418,11092,1.52505087169334,0.230400911608131,0.300242374105489,"MAPK3;MAPK1;PRKCB;BIRC5;CCNB1"]
["R-HSA-192105","Synthesis of bile acids and bile salts",1,87,34,11092,3.74983096686951,0.235192171066238,0.304978700513762,"NCOA2"]
["R-HSA-4791275","Signaling by WNT in cancer",1,87,34,11092,3.74983096686951,0.235192171066238,0.304978700513762,"CTNNB1"]
["R-HSA-5579029","Metabolic disorders of biological oxidation enzymes",1,87,34,11092,3.74983096686951,0.235192171066238,0.304978700513762,"CYP1B1"]
["R-HSA-1500620","Meiosis",2,87,118,11092,2.16091954022989,0.236596102835295,0.306297082393974,"BRCA1;BRCA2"]
["R-HSA-418594","G alpha (i) signalling events",4,87,318,11092,1.60370129400708,0.239135471796983,0.309044131434597,"MAPK1;PRKCD;CXCL8;CCR2"]
["R-HSA-373760","L1CAM interactions",2,87,119,11092,2.14276055249686,0.239499434348177,0.309044131434597,"MAPK3;MAPK1"]
["R-HSA-114604","GPVI-mediated activation cascade",1,87,35,11092,3.64269293924466,0.241209378618891,0.309734770271985,"CDC42"]
["R-HSA-3301854","Nuclear Pore Complex (NPC) Disassembly",1,87,35,11092,3.64269293924466,0.241209378618891,0.309734770271985,"CCNB1"]
["R-HSA-8953750","Transcriptional Regulation by E2F6",1,87,35,11092,3.64269293924466,0.241209378618891,0.309734770271985,"BRCA1"]
["R-HSA-202403","TCR signaling",2,87,120,11092,2.12490421455939,0.242404689734633,0.310765169497723,"RELA;NFKBIA"]
["R-HSA-8956319","Nucleotide catabolism",1,87,36,11092,3.54150702426564,0.247179785063692,0.316374126189936,"XDH"]
["R-HSA-5689880","Ub-specific processing proteases",3,87,220,11092,1.73855799373041,0.248486411770571,0.317532716818291,"NFKBIA;MYC;TRAF2"]
["R-HSA-196849","Metabolism of water-soluble vitamins and cofactors",2,87,123,11092,2.07307728249696,0.251129953426237,0.319306326027282,"PTGS2;CD320"]
["R-HSA-111933","Calmodulin induced events",1,87,37,11092,3.44579061820441,0.253103750213788,0.319306326027282,"PRKCD"]
["R-HSA-111997","CaM pathway",1,87,37,11092,3.44579061820441,0.253103750213788,0.319306326027282,"PRKCD"]
["R-HSA-168638","NOD1/2 Signaling Pathway",1,87,37,11092,3.44579061820441,0.253103750213788,0.319306326027282,"CASP9"]
["R-HSA-3299685","Detoxification of Reactive Oxygen Species",1,87,37,11092,3.44579061820441,0.253103750213788,0.319306326027282,"CAT"]
["R-HSA-5685938","HDR through Single Strand Annealing (SSA)",1,87,37,11092,3.44579061820441,0.253103750213788,0.319306326027282,"BRCA1"]
["R-HSA-5689901","Metalloprotease DUBs",1,87,37,11092,3.44579061820441,0.253103750213788,0.319306326027282,"BRCA1"]
["R-HSA-9029569","NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux",1,87,37,11092,3.44579061820441,0.253103750213788,0.319306326027282,"NR1H3"]
["R-HSA-9013424","RHOV GTPase cycle",1,87,38,11092,3.35511191772535,0.258981631148333,0.326201385729827,"CDC42"]
["R-HSA-2500257","Resolution of Sister Chromatid Cohesion",2,87,126,11092,2.02371829958037,0.259865293471112,0.326794033601986,"BIRC5;CCNB1"]
["R-HSA-195721","Signaling by WNT",4,87,332,11092,1.53607533582606,0.263167000850416,0.330420789956634,"AKT1;CTNNB1;MYC;PRKCB"]
["R-HSA-422475","Axon guidance",6,87,552,11092,1.38580709645177,0.264851946708131,0.332009334146008,"MMP2;MMP9;MAPK3;MAPK1;MAPK8;CDC42"]
["R-HSA-373076","Class A/1 (Rhodopsin-like receptors)",4,87,335,11092,1.52231943729628,0.268379900889691,0.335368880890593,"EDN1;CXCL8;AGTR1;CCR2"]
["R-HSA-73894","DNA Repair",4,87,335,11092,1.52231943729628,0.268379900889691,0.335368880890593,"MAPK8;BRCA1;XRCC6;BRCA2"]
["R-HSA-1461957","Beta defensins",1,87,40,11092,3.18735632183908,0.270600555140438,0.336548803641645,"CCR2"]
["R-HSA-9013420","RHOU GTPase cycle",1,87,40,11092,3.18735632183908,0.270600555140438,0.336548803641645,"CDC42"]
["R-HSA-9664323","FCGR3A-mediated IL10 synthesis",1,87,40,11092,3.18735632183908,0.270600555140438,0.336548803641645,"IL10"]
["R-HSA-392499","Metabolism of proteins",18,87,1966,11092,1.16729224401024,0.272405133548424,0.33826131968101,"NCOA2;RELA;STAT3;MMP2;IL6;NFKBIA;PPARG;CTNNB1;MYC;BRCA1;BIRC5;PPARA;CCNE1;EIF2S1;TRAF2;NR1H3;PAPPA;TGFA"]
["R-HSA-201681","TCF dependent signaling in response to WNT",3,87,233,11092,1.64155690395146,0.27604892895875,0.342076304235418,"AKT1;CTNNB1;MYC"]
["R-HSA-8875878","MET promotes cell motility",1,87,41,11092,3.10961592374544,0.276342298870331,0.342076304235418,"HGF"]
["R-HSA-5693567","HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA)",2,87,132,11092,1.9317311041449,0.277345777875173,0.342782047342597,"BRCA1;BRCA2"]
["R-HSA-2173782","Binding and Uptake of Ligands by Scavenger Receptors",1,87,42,11092,3.03557744937055,0.282039359769642,0.347497092800291,"SPARC"]
["R-HSA-3928662","EPHB-mediated forward signaling",1,87,42,11092,3.03557744937055,0.282039359769642,0.347497092800291,"CDC42"]
["R-HSA-1489509","DAG and IP3 signaling",1,87,43,11092,2.96498262496659,0.287692081552451,0.353910476684275,"PRKCD"]
["R-HSA-1632852","Macroautophagy",2,87,136,11092,1.87491548343475,0.288991276412044,0.354956676462619,"PRKAG2;MTOR"]
["R-HSA-109704","PI3K Cascade",1,87,44,11092,2.89759665621735,0.293300805319755,0.35913457741165,"IRS1"]
["R-HSA-9749641","Aspirin ADME",1,87,44,11092,2.89759665621735,0.293300805319755,0.35913457741165,"BSG"]
["R-HSA-5693538","Homology Directed Repair",2,87,138,11092,1.84774279526903,0.294807549859905,0.360421594960101,"BRCA1;BRCA2"]
["R-HSA-9675108","Nervous system development",6,87,577,11092,1.32576346142353,0.2988562580282,0.363138099596104,"MMP2;MMP9;MAPK3;MAPK1;MAPK8;CDC42"]
["R-HSA-194068","Bile acid and bile salt metabolism",1,87,45,11092,2.83320561941252,0.298865869579094,0.363138099596104,"NCOA2"]
["R-HSA-3899300","SUMOylation of transcription cofactors",1,87,45,11092,2.83320561941252,0.298865869579094,0.363138099596104,"NCOA2"]
["R-HSA-4615885","SUMOylation of DNA replication proteins",1,87,45,11092,2.83320561941252,0.298865869579094,0.363138099596104,"BIRC5"]
["R-HSA-5663220","RHO GTPases Activate Formins",2,87,140,11092,1.82134646962233,0.300617812073062,0.36470657875735,"BIRC5;CDC42"]
["R-HSA-1474165","Reproduction",2,87,143,11092,1.78313640382606,0.309319274585486,0.374688432154853,"BRCA1;BRCA2"]
["R-HSA-437239","Recycling pathway of L1",1,87,47,11092,2.71264367816092,0.309866360753543,0.374777203908337,"MAPK1"]
["R-HSA-112399","IRS-mediated signalling",1,87,48,11092,2.65613026819923,0.315302451891111,0.379610714529481,"IRS1"]
["R-HSA-2122947","NOTCH1 Intracellular Domain Regulates Transcription",1,87,48,11092,2.65613026819923,0.315302451891111,0.379610714529481,"MYC"]
["R-HSA-512988","Interleukin-3, Interleukin-5 and GM-CSF signaling",1,87,48,11092,2.65613026819923,0.315302451891111,0.379610714529481,"JAK1"]
["R-HSA-3858494","Beta-catenin independent WNT signaling",2,87,146,11092,1.74649661470635,0.318000516732552,0.381697130099315,"CTNNB1;PRKCB"]
["R-HSA-8856828","Clathrin-mediated endocytosis",2,87,146,11092,1.74649661470635,0.318000516732552,0.381697130099315,"AGTR1;TGFA"]
["R-HSA-9012852","Signaling by NOTCH3",1,87,49,11092,2.6019235280319,0.320696212003885,0.384349551053141,"STAT1"]
["R-HSA-1461973","Defensins",1,87,51,11092,2.49988731124634,0.331358039995062,0.395330632935285,"CCR2"]
["R-HSA-350562","Regulation of ornithine decarboxylase (ODC)",1,87,51,11092,2.49988731124634,0.331358039995062,0.395330632935285,"ODC1"]
["R-HSA-72695","Formation of the ternary complex, and subsequently, the 43S complex",1,87,51,11092,2.49988731124634,0.331358039995062,0.395330632935285,"EIF2S1"]
["R-HSA-9612973","Autophagy",2,87,151,11092,1.68866560097435,0.33241416808591,0.395993383969812,"PRKAG2;MTOR"]
["R-HSA-2428928","IRS-related events triggered by IGF1R",1,87,52,11092,2.45181255526083,0.33662675211538,0.399807448833732,"IRS1"]
["R-HSA-75815","Ubiquitin-dependent degradation of Cyclin D",1,87,52,11092,2.45181255526083,0.33662675211538,0.399807448833732,"CCND1"]
["R-HSA-2428924","IGF1R signaling cascade",1,87,53,11092,2.40555194101063,0.341854421731861,0.405407567601053,"IRS1"]
["R-HSA-2404192","Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R)",1,87,54,11092,2.36100468284376,0.347041364870672,0.410328429914352,"IRS1"]
["R-HSA-9604323","Negative regulation of NOTCH4 signaling",1,87,54,11092,2.36100468284376,0.347041364870672,0.410328429914352,"AKT1"]
["R-HSA-71406","Pyruvate metabolism and Citric Acid (TCA) cycle",1,87,55,11092,2.31807732497388,0.352187895152992,0.414554501586334,"BSG"]
["R-HSA-9013409","RHOJ GTPase cycle",1,87,55,11092,2.31807732497388,0.352187895152992,0.414554501586334,"CDC42"]
["R-HSA-9639288","Amino acids regulate mTORC1",1,87,55,11092,2.31807732497388,0.352187895152992,0.414554501586334,"MTOR"]
["R-HSA-3247509","Chromatin modifying enzymes",3,87,274,11092,1.39592247671785,0.364237771619767,0.425481690361888,"NCOA2;RELA;CCND1"]
["R-HSA-4839726","Chromatin organization",3,87,274,11092,1.39592247671785,0.364237771619767,0.425481690361888,"NCOA2;RELA;CCND1"]
["R-HSA-1236394","Signaling by ERBB4",1,87,58,11092,2.19817677368212,0.367388109376953,0.425481690361888,"SPARC"]
["R-HSA-166658","Complement cascade",1,87,58,11092,2.19817677368212,0.367388109376953,0.425481690361888,"CRP"]
["R-HSA-2644602","Signaling by NOTCH1 PEST Domain Mutants in Cancer",1,87,58,11092,2.19817677368212,0.367388109376953,0.425481690361888,"MYC"]
["R-HSA-2644603","Signaling by NOTCH1 in Cancer",1,87,58,11092,2.19817677368212,0.367388109376953,0.425481690361888,"MYC"]
["R-HSA-2644606","Constitutive Signaling by NOTCH1 PEST Domain Mutants",1,87,58,11092,2.19817677368212,0.367388109376953,0.425481690361888,"MYC"]
["R-HSA-2894858","Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer",1,87,58,11092,2.19817677368212,0.367388109376953,0.425481690361888,"MYC"]
["R-HSA-2894862","Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants",1,87,58,11092,2.19817677368212,0.367388109376953,0.425481690361888,"MYC"]
["R-HSA-72649","Translation initiation complex formation",1,87,58,11092,2.19817677368212,0.367388109376953,0.425481690361888,"EIF2S1"]
["R-HSA-72702","Ribosomal scanning and start codon recognition",1,87,58,11092,2.19817677368212,0.367388109376953,0.425481690361888,"EIF2S1"]
["R-HSA-351202","Metabolism of polyamines",1,87,59,11092,2.16091954022989,0.372376076975666,0.429372415288268,"ODC1"]
["R-HSA-72662","Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S",1,87,59,11092,2.16091954022989,0.372376076975666,0.429372415288268,"EIF2S1"]
["R-HSA-9013406","RHOQ GTPase cycle",1,87,59,11092,2.16091954022989,0.372376076975666,0.429372415288268,"CDC42"]
["R-HSA-5607761","Dectin-1 mediated noncanonical NF-kB signaling",1,87,60,11092,2.12490421455939,0.377325164377381,0.43444571327876,"RELA"]
["R-HSA-69481","G2/M Checkpoints",2,87,168,11092,1.51778872468528,0.380713445196642,0.437709789463,"BRCA1;CCNB1"]
["R-HSA-2022090","Assembly of collagen fibrils and other multimeric structures",1,87,61,11092,2.09006971923874,0.382235671148516,0.438822084003594,"MMP9"]
["R-HSA-9662851","Anti-inflammatory response favouring Leishmania parasite infection",2,87,169,11092,1.50880772631436,0.383512947992657,0.439014098208671,"IL10;IL6"]
["R-HSA-9664433","Leishmania parasite growth and survival",2,87,169,11092,1.50880772631436,0.383512947992657,0.439014098208671,"IL10;IL6"]
["R-HSA-4086398","Ca2+ pathway",1,87,62,11092,2.05635891731554,0.387107894574323,0.442488937295217,"CTNNB1"]
["R-HSA-73728","RNA Polymerase I Promoter Opening",1,87,63,11092,2.02371829958037,0.391942129676049,0.446723666532788,"MAPK3"]
["R-HSA-9033241","Peroxisomal protein import",1,87,63,11092,2.02371829958037,0.391942129676049,0.446723666532788,"CAT"]
["R-HSA-421270","Cell-cell junction organization",1,87,64,11092,1.99209770114943,0.396738669227974,0.451539981811982,"CTNNB1"]
["R-HSA-6796648","TP53 Regulates Transcription of DNA Repair Genes",1,87,65,11092,1.96145004420866,0.401497803774326,0.456271345359963,"BRCA1"]
["R-HSA-112316","Neuronal System",4,87,410,11092,1.24384636949818,0.402049466138931,0.456271345359963,"MAPK3;MAPK1;PRKCB;PRKAG2"]
["R-HSA-5625886","Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3",1,87,67,11092,1.90289929662035,0.410905008977532,0.465269752539091,"NCOA2"]
["R-HSA-1852241","Organelle biogenesis and maintenance",3,87,296,11092,1.29217148182665,0.411154939348703,0.465269752539091,"NCOA2;PRKAG2;PPARA"]
["R-HSA-204005","COPII-mediated vesicle transport",1,87,68,11092,1.87491548343475,0.415553649723016,0.469575624187008,"TGFA"]
["R-HSA-8948751","Regulation of PTEN stability and activity",1,87,69,11092,1.84774279526903,0.420166025673134,0.474110308569827,"AKT1"]
["R-HSA-174824","Plasma lipoprotein assembly, remodeling, and clearance",1,87,70,11092,1.82134646962233,0.424742416471141,0.47859152625167,"NR1H3"]
["R-HSA-3214841","PKMTs methylate histone lysines",1,87,71,11092,1.79569370244455,0.429283099629099,0.483019817648104,"RELA"]
["R-HSA-5653656","Vesicle-mediated transport",6,87,673,11092,1.1366500999129,0.434456126277211,0.488146016882491,"AKT1;PRKAG2;SLC2A4;AGTR1;SPARC;TGFA"]
["R-HSA-69017","CDK-mediated phosphorylation and removal of Cdc6",1,87,73,11092,1.74649661470635,0.438258442513312,0.491023269161516,"CCNE1"]
["R-HSA-8939902","Regulation of RUNX2 expression and activity",1,87,73,11092,1.74649661470635,0.438258442513312,0.491023269161516,"STAT1"]
["R-HSA-1980143","Signaling by NOTCH1",1,87,74,11092,1.72289530910221,0.442693646751568,0.493893758223541,"MYC"]
["R-HSA-2299718","Condensation of Prophase Chromosomes",1,87,74,11092,1.72289530910221,0.442693646751568,0.493893758223541,"CCNB1"]
["R-HSA-9013408","RHOG GTPase cycle",1,87,74,11092,1.72289530910221,0.442693646751568,0.493893758223541,"CDC42"]
["R-HSA-1234174","Cellular response to hypoxia",1,87,75,11092,1.69992337164751,0.447094232405282,0.497400193857353,"VEGFA"]
["R-HSA-2995410","Nuclear Envelope (NE) Reassembly",1,87,75,11092,1.69992337164751,0.447094232405282,0.497400193857353,"CCNB1"]
["R-HSA-176409","APC/C:Cdc20 mediated degradation of mitotic proteins",1,87,76,11092,1.67755595886267,0.451460466568914,0.500848848605907,"CCNB1"]
["R-HSA-3000178","ECM proteoglycans",1,87,76,11092,1.67755595886267,0.451460466568914,0.500848848605907,"SPARC"]
["R-HSA-597592","Post-translational protein modification",12,87,1435,11092,1.06615403099844,0.453250481778233,0.502130435695493,"NCOA2;RELA;IL6;NFKBIA;PPARG;MYC;BRCA1;BIRC5;PPARA;TRAF2;NR1H3;TGFA"]
["R-HSA-176814","Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins",1,87,77,11092,1.65576951783848,0.45579261430026,0.503536254066348,"CCNB1"]
["R-HSA-3108214","SUMOylation of DNA damage response and repair proteins",1,87,77,11092,1.65576951783848,0.45579261430026,0.503536254066348,"BRCA1"]
["R-HSA-69275","G2/M Transition",2,87,196,11092,1.30096176401595,0.45685323410981,0.504004056040251,"CDKN1A;CCNB1"]
["R-HSA-453274","Mitotic G2-G2/M phases",2,87,198,11092,1.2878207360966,0.462093415276949,0.509075057777252,"CDKN1A;CCNB1"]
["R-HSA-1221632","Meiotic synapsis",1,87,79,11092,1.613851302197,0.464355700605892,0.510146332193417,"BRCA1"]
["R-HSA-3214858","RMTs methylate histone arginines",1,87,79,11092,1.613851302197,0.464355700605892,0.510146332193417,"CCND1"]
["R-HSA-176408","Regulation of APC/C activators between G1/S and early anaphase",1,87,81,11092,1.57400312189584,0.472785571631491,0.517968680277713,"CCNB1"]
["R-HSA-9663891","Selective autophagy",1,87,81,11092,1.57400312189584,0.472785571631491,0.517968680277713,"PRKAG2"]
["R-HSA-9013694","Signaling by NOTCH4",1,87,82,11092,1.55480796187272,0.47695119285282,0.52180967295516,"AKT1"]
["R-HSA-68877","Mitotic Prometaphase",2,87,204,11092,1.24994365562317,0.477638771094423,0.521840149082443,"BIRC5;CCNB1"]
["R-HSA-195253","Degradation of beta-catenin by the destruction complex",1,87,83,11092,1.53607533582606,0.48108427607006,0.524879534305403,"CTNNB1"]
["R-HSA-425366","Transport of bile salts and organic acids, metal ions and amine compounds",1,87,85,11092,1.4999323867478,0.489253831473157,0.533057549167035,"BSG"]
["R-HSA-174143","APC/C-mediated degradation of cell cycle proteins",1,87,88,11092,1.44879832810867,0.501270348158015,0.542771513060822,"CCNB1"]
["R-HSA-2565942","Regulation of PLK1 Activity at G2/M Transition",1,87,88,11092,1.44879832810867,0.501270348158015,0.542771513060822,"CCNB1"]
["R-HSA-453276","Regulation of mitotic cell cycle",1,87,88,11092,1.44879832810867,0.501270348158015,0.542771513060822,"CCNB1"]
["R-HSA-9013404","RAC2 GTPase cycle",1,87,88,11092,1.44879832810867,0.501270348158015,0.542771513060822,"CDC42"]
["R-HSA-500792","GPCR ligand binding",4,87,467,11092,1.09202786187206,0.501600475407662,0.542771513060822,"EDN1;CXCL8;AGTR1;CCR2"]
["R-HSA-1474290","Collagen formation",1,87,90,11092,1.41660280970626,0.509125657597339,0.549411180299448,"MMP9"]
["R-HSA-8876198","RAB GEFs exchange GTP for GDP on RABs",1,87,90,11092,1.41660280970626,0.509125657597339,0.549411180299448,"AKT1"]
["R-HSA-2980736","Peptide hormone metabolism",1,87,91,11092,1.40103574586333,0.513007321639243,0.552093593764138,"CTNNB1"]
["R-HSA-446728","Cell junction organization",1,87,91,11092,1.40103574586333,0.513007321639243,0.552093593764138,"CTNNB1"]
["R-HSA-4086400","PCP/CE pathway",1,87,92,11092,1.38580709645177,0.516858640884529,0.554728880515146,"PRKCB"]
["R-HSA-69052","Switching of origins to a post-replicative state",1,87,92,11092,1.38580709645177,0.516858640884529,0.554728880515146,"CCNE1"]
["R-HSA-1912408","Pre-NOTCH Transcription and Translation",1,87,93,11092,1.37090594487702,0.520679849815715,0.558072847160204,"CCND1"]
["R-HSA-9013423","RAC3 GTPase cycle",1,87,94,11092,1.35632183908046,0.524471181124564,0.561375783855927,"CDC42"]
["R-HSA-5625740","RHO GTPases activate PKNs",1,87,95,11092,1.34204476709014,0.528232865725597,0.564638103768848,"NCOA2"]
["R-HSA-141424","Amplification of signal from the kinetochores",1,87,96,11092,1.32806513409962,0.531965132769507,0.566331655478708,"BIRC5"]
["R-HSA-141444","Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal",1,87,96,11092,1.32806513409962,0.531965132769507,0.566331655478708,"BIRC5"]
["R-HSA-6803157","Antimicrobial peptides",1,87,96,11092,1.32806513409962,0.531965132769507,0.566331655478708,"CCR2"]
["R-HSA-5619102","SLC transporter disorders",1,87,98,11092,1.30096176401595,0.539342322049366,0.572643995625568,"BSG"]
["R-HSA-5693607","Processing of DNA double-strand break ends",1,87,98,11092,1.30096176401595,0.539342322049366,0.572643995625568,"BRCA1"]
["R-HSA-15869","Metabolism of nucleotides",1,87,99,11092,1.2878207360966,0.542987693886887,0.575741643250037,"XDH"]
["R-HSA-5668541","TNFR2 non-canonical NF-kB pathway",1,87,102,11092,1.24994365562317,0.553753579864072,0.58637092593371,"TRAF2"]
["R-HSA-68882","Mitotic Anaphase",2,87,236,11092,1.08045977011494,0.555805643714283,0.58775703767112,"BIRC5;CCNB1"]
["R-HSA-382556","ABC-family proteins mediated transport",1,87,103,11092,1.23780828032586,0.557286194836941,0.588535888005367,"EIF2S1"]
["R-HSA-2555396","Mitotic Metaphase and Anaphase",2,87,237,11092,1.07590086813134,0.558113776667122,0.588623996458258,"BIRC5;CCNB1"]
["R-HSA-199991","Membrane Trafficking",5,87,634,11092,1.00547518039088,0.560436767110555,0.590286927808853,"AKT1;PRKAG2;SLC2A4;AGTR1;TGFA"]
["R-HSA-8878171","Transcriptional regulation by RUNX1",2,87,239,11092,1.0668975135863,0.56270491993037,0.591887754873568,"CCND1;PRKCB"]
["R-HSA-162906","HIV Infection",2,87,241,11092,1.05804359231173,0.567262489082226,0.595889281359948,"XRCC6;CD28"]
["R-HSA-8957275","Post-translational protein phosphorylation",1,87,108,11092,1.18050234142188,0.574538828434716,0.602732378371168,"IL6"]
["R-HSA-5668914","Diseases of metabolism",2,87,245,11092,1.04076941121276,0.576276583118586,0.603754671850068,"CYP1B1;CD320"]
["R-HSA-1912422","Pre-NOTCH Expression and Processing",1,87,109,11092,1.16967204471159,0.577908741210224,0.604663775525512,"CCND1"]
["R-HSA-156827","L13a-mediated translational silencing of Ceruloplasmin expression",1,87,111,11092,1.1485968727348,0.58456960888404,0.610019209270812,"EIF2S1"]
["R-HSA-73854","RNA Polymerase I Promoter Clearance",1,87,111,11092,1.1485968727348,0.58456960888404,0.610019209270812,"MAPK3"]
["R-HSA-425407","SLC-mediated transmembrane transport",2,87,250,11092,1.01995402298851,0.587354087532407,0.611839510287331,"SLC2A4;BSG"]
["R-HSA-72706","GTP hydrolysis and joining of the 60S ribosomal subunit",1,87,112,11092,1.13834154351396,0.587860970693264,0.611839510287331,"EIF2S1"]
["R-HSA-69618","Mitotic Spindle Checkpoint",1,87,113,11092,1.12826772454481,0.591126553165913,0.614429833842625,"BIRC5"]
["R-HSA-73864","RNA Polymerase I Transcription",1,87,114,11092,1.11837063924178,0.594366555886977,0.616986805389238,"MAPK3"]
["R-HSA-9648025","EML4 and NUDC in mitotic spindle formation",1,87,117,11092,1.08969446900481,0.603935058552395,0.626097812994685,"BIRC5"]
["R-HSA-72613","Eukaryotic Translation Initiation",1,87,119,11092,1.07138027624843,0.610189752436375,0.630928227682579,"EIF2S1"]
["R-HSA-72737","Cap-dependent Translation Initiation",1,87,119,11092,1.07138027624843,0.610189752436375,0.630928227682579,"EIF2S1"]
["R-HSA-69239","Synthesis of DNA",1,87,121,11092,1.05367151135176,0.616346789217957,0.636462546046219,"CCNE1"]
["R-HSA-9007101","Rab regulation of trafficking",1,87,124,11092,1.02817945865777,0.625402528254811,0.644971838135014,"AKT1"]
["R-HSA-1500931","Cell-Cell communication",1,87,129,11092,0.988327541655529,0.640028168558484,0.659195678814792,"CTNNB1"]
["R-HSA-198933","Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell",1,87,133,11092,0.958603405064385,0.651321029418946,0.669954400871764,"VCAM1"]
["R-HSA-9660821","ADORA2B mediated anti-inflammatory cytokines production",1,87,134,11092,0.951449648310173,0.654089080376201,0.67192787347737,"IL6"]
["R-HSA-162909","Host Interactions of HIV factors",1,87,136,11092,0.937457741717377,0.659560178600957,0.676669392053641,"CD28"]
["R-HSA-3214847","HATs acetylate histones",1,87,142,11092,0.897846851222276,0.675465416096424,0.692089564938176,"NCOA2"]
["R-HSA-199977","ER to Golgi Anterograde Transport",1,87,154,11092,0.827884758919242,0.705104646855166,0.721523642512854,"TGFA"]
["R-HSA-9013148","CDC42 GTPase cycle",1,87,155,11092,0.822543566926214,0.707450221523625,0.722988533882671,"CDC42"]
["R-HSA-162587","HIV Life Cycle",1,87,159,11092,0.801850647003542,0.716649510623336,0.731444855358786,"XRCC6"]
["R-HSA-9609507","Protein localization",1,87,163,11092,0.782173330512658,0.725562747485371,0.73958780059398,"CAT"]
["R-HSA-983231","Factors involved in megakaryocyte development and platelet production",1,87,168,11092,0.758894362342638,0.736315405006726,0.749582349241082,"CDC42"]
["R-HSA-5619115","Disorders of transmembrane transporters",1,87,176,11092,0.724399164054337,0.752659706006901,0.765236282071283,"BSG"]
["R-HSA-1428517","The citric acid (TCA) cycle and respiratory electron transport",1,87,178,11092,0.716259847604288,0.756586754802417,0.768241493002197,"BSG"]
["R-HSA-9013149","RAC1 GTPase cycle",1,87,185,11092,0.689158123640882,0.769852214563944,0.779709477234417,"CDC42"]
["R-HSA-948021","Transport to the Golgi and subsequent modification",1,87,185,11092,0.689158123640882,0.769852214563944,0.779709477234417,"TGFA"]
["R-HSA-69306","DNA Replication",1,87,188,11092,0.67816091954023,0.775316240227757,0.784239317161325,"CCNE1"]
["R-HSA-2467813","Separation of Sister Chromatids",1,87,191,11092,0.667509177348498,0.780651998400262,0.788628008601031,"BIRC5"]
["R-HSA-376176","Signaling by ROBO receptors",1,87,218,11092,0.584836022355795,0.823371130877149,0.830722658831409,"CDC42"]
["R-HSA-382551","Transport of small molecules",4,87,729,11092,0.699556943064819,0.832231924644871,0.838592932986105,"SLC2A4;EIF2S1;BSG;NR1H3"]
["R-HSA-8951664","Neddylation",1,87,234,11092,0.544847234502407,0.844688147987307,0.850061482262036,"BIRC5"]
["R-HSA-72766","Translation",1,87,291,11092,0.438124580321523,0.901929153706478,0.906513291717692,"EIF2S1"]
["R-HSA-446203","Asparagine N-linked glycosylation",1,87,304,11092,0.419388989715668,0.911721646697149,0.915192668194727,"TGFA"]
["R-HSA-71291","Metabolism of amino acids and derivatives",1,87,374,11092,0.340893724260864,0.950008033309578,0.952416165206434,"ODC1"]
["R-HSA-8953854","Metabolism of RNA",2,87,675,11092,0.377760749255002,0.97224952375823,0.97292907261552,"AKT1;PRKCD"]
["R-HSA-9012999","RHO GTPase cycle",1,87,449,11092,0.283951565419963,0.97292907261552,0.97292907261552,"CDC42"]

{"sheet":"S7(Grayscale value)","index":6,"n_rows":16,"n_cols":9,"rows_kept":16,"flags":["formulas_cached_only"]}
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