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["ENSAPLG00000013511","TAPBPL","ENSAPLT00000025992;ENSAPLT00000039689;ENSAPLT00000020082;ENSAPLT00000044654;ENSAPLT00000014139;ENSAPLT00000037890;ENSAPLT00000023369;ENSAPLT00000012874","GO:0002502(peptide antigen assembly with MHC class I protein complex);GO:0002590(negative regulation of antigen processing and presentation of peptide antigen via MHC class I);GO:0006006(glucose metabolic process);GO:0016620(oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor);GO:0023024(MHC class I protein complex binding);GO:0044877(protein-containing complex binding);GO:0050661(NADP binding);GO:0051287(NAD binding);GO:0055114(oxidation-reduction process);GO:0055114(oxidation-reduction process)","00010(Glycolysis / Gluconeogenesis);00010(Glycolysis / Gluconeogenesis)","K00134","EC:1.2.1.12","TAP binding protein like [Source:HGNC Symbol;Acc:HGNC:30683]","NA",{"v":3136.2087444298,"d":"3136.21"},{"v":3151.87579830388,"d":"3151.88"},{"v":3260.69354420208,"d":"3260.69"},{"v":2448.05987994212,"d":"2448.06"},{"v":3064.32459373496,"d":"3064.32"},{"v":4054.00905353542,"d":"4054.01"},{"v":3445.52404590327,"d":"3445.52"},{"v":3154.63373431175,"d":"3154.63"},{"v":14726.0267731574,"d":"14726.03"},{"v":14010.8406222244,"d":"14010.84"},{"v":19175.4907577819,"d":"19175.49"},{"v":15842.4978038576,"d":"15842.50"},{"v":14047.2099783455,"d":"14047.21"},{"v":15965.1681229292,"d":"15965.17"},{"v":15454.6885109477,"d":"15454.69"},{"v":17068.9270954836,"d":"17068.93"},{"v":0.203619893781944,"d":"0.20"},{"v":-2.29604957444392,"d":"-2.30"},{"v":4.76073989045687e-91,"d":"0.00"},{"v":3.08704227271813e-88,"d":"0.00"},"down","yes"]
["ENSAPLG00000001185","GJA5","ENSAPLT00000001171","GO:0001501(skeletal system development);GO:0001525(angiogenesis);GO:0001568(blood vessel development);GO:0003071(renal system process involved in regulation of systemic arterial blood pressure);GO:0003073(regulation of systemic arterial blood pressure);GO:0003151(outflow tract morphogenesis);GO:0003161(cardiac conduction system development);GO:0003174(mitral valve development);GO:0003193(pulmonary valve formation);GO:0003281(ventricular septum development);GO:0003283(atrial septum development);GO:0003284(septum primum development);GO:0003294(atrial ventricular junction remodeling);GO:0005887(integral component of plasma membrane);GO:0005921(gap junction);GO:0005922(connexin complex);GO:0007154(cell communication);GO:0014704(intercalated disc);GO:0016264(gap junction assembly);GO:0030326(embryonic limb morphogenesis);GO:0035050(embryonic heart tube development);GO:0035922(foramen ovale closure);GO:0048844(artery morphogenesis);GO:0055077(gap junction hemi-channel activity);GO:0055117(regulation of cardiac muscle contraction);GO:0060307(regulation of ventricular cardiac muscle cell membrane repolarization);GO:0060371(regulation of atrial cardiac muscle cell membrane depolarization);GO:0060373(regulation of ventricular cardiac muscle cell membrane depolarization);GO:0060412(ventricular septum morphogenesis);GO:0060413(atrial septum morphogenesis);GO:0061337(cardiac conduction);GO:0086005(ventricular cardiac muscle cell action potential);GO:0086015(SA node cell action potential);GO:0086044(atrial cardiac muscle cell to AV node cell communication by electrical coupling);GO:0086053(AV node cell to bundle of His cell communication by electrical coupling);GO:0086054(bundle of His cell to Purkinje myocyte communication by electrical coupling);GO:0086064(cell communication by electrical coupling involved in cardiac conduction);GO:0086065(cell communication involved in cardiac conduction);GO:0086067(AV node cell to bundle of His cell communication);GO:0086075(gap junction channel activity involved in cardiac conduction electrical coupling);GO:0086076(gap junction channel activity involved in atrial cardiac muscle cell-AV node cell electrical coupling);GO:0086077(gap junction channel activity involved in AV node cell-bundle of His cell electrical coupling);GO:0086078(gap junction channel activity involved in bundle of His cell-Purkinje myocyte electrical coupling);GO:0086091(regulation of heart rate by cardiac conduction);GO:0097746(regulation of blood vessel diameter);GO:0098904(regulation of AV node cell action potential);GO:0098905(regulation of bundle of His cell action potential);GO:0098906(regulation of Purkinje myocyte action potential);GO:0098910(regulation of atrial cardiac muscle cell action potential);GO:1900133(regulation of renin secretion into blood stream);GO:1900825(regulation of membrane depolarization during cardiac muscle cell action potential)","NA","NA","NA","gap junction protein alpha 5 [Source:HGNC Symbol;Acc:HGNC:4279]","NA",{"v":237.52565,"d":"237.53"},{"v":160.960434,"d":"160.96"},{"v":270.986359,"d":"270.99"},{"v":176.884354,"d":"176.88"},{"v":164.631973,"d":"164.63"},{"v":228.192841,"d":"228.19"},{"v":228.273209,"d":"228.27"},{"v":216.695251,"d":"216.70"},{"v":19.584146,"d":"19.58"},{"v":24.657114,"d":"24.66"},{"v":15.942528,"d":"15.94"},{"v":20.040228,"d":"20.04"},{"v":16.111887,"d":"16.11"},{"v":13.532496,"d":"13.53"},{"v":15.833944,"d":"15.83"},{"v":16.832047,"d":"16.83"},{"v":11.8157454562369,"d":"11.82"},{"v":3.56263874680512,"d":"3.56"},{"v":5.38564299934657e-91,"d":"0.00"},{"v":3.28682624224827e-88,"d":"0.00"},"up","yes"]
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["ENSAPLG00000013543","ASB11","ENSAPLT00000014107","GO:0005515(protein binding);GO:0005783(endoplasmic reticulum);GO:0035556(intracellular signal transduction)","NA","NA","NA","ankyrin repeat and SOCS box containing 11 [Source:HGNC Symbol;Acc:HGNC:17186]","NA",{"v":0.108421,"d":"0.11"},{"v":0.0001,"d":"0.00"},{"v":0.0001,"d":"0.00"},{"v":0.405487,"d":"0.41"},{"v":0.399466,"d":"0.40"},{"v":0.0001,"d":"0.00"},{"v":0.258826,"d":"0.26"},{"v":0.227158,"d":"0.23"},{"v":16.029818,"d":"16.03"},{"v":21.217785,"d":"21.22"},{"v":27.081711,"d":"27.08"},{"v":22.280027,"d":"22.28"},{"v":34.874447,"d":"34.87"},{"v":15.212088,"d":"15.21"},{"v":23.827534,"d":"23.83"},{"v":19.068291,"d":"19.07"},{"v":0.00779355611760701,"d":"0.01"},{"v":-7.00350251958616,"d":"-7.00"},{"v":1.34988568484623e-82,"d":"0.00"},{"v":6.36593817285438e-80,"d":"0.00"},"down","yes"]
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["ENSAPLG00000031131","FHL1","ENSAPLT00000036703;ENSAPLT00000017799;ENSAPLT00000035577;ENSAPLT00000043879","NA","04630(Jak-STAT signaling pathway);04630(Jak-STAT signaling pathway)","K14365","NA","four and a half LIM domains 1 [Source:HGNC Symbol;Acc:HGNC:3702]","NA",{"v":89.5169397782875,"d":"89.52"},{"v":167.014133642202,"d":"167.01"},{"v":217.774251285933,"d":"217.77"},{"v":164.980634409786,"d":"164.98"},{"v":201.359180287462,"d":"201.36"},{"v":274.959778368502,"d":"274.96"},{"v":97.320008941896,"d":"97.32"},{"v":119.20587962844,"d":"119.21"},{"v":844.769664637615,"d":"844.77"},{"v":859.928382311927,"d":"859.93"},{"v":952.192945053517,"d":"952.19"},{"v":965.829763669725,"d":"965.83"},{"v":1152.5037718685,"d":"1152.50"},{"v":1385.1633560948,"d":"1385.16"},{"v":1118.14616602446,"d":"1118.15"},{"v":778.016613561162,"d":"778.02"},{"v":0.165347536685111,"d":"0.17"},{"v":-2.59642654218353,"d":"-2.60"},{"v":5.44058267068059e-50,"d":"0.00"},{"v":5.94168896929591e-48,"d":"0.00"},"down","yes"]
["ENSAPLG00000004563","CD36","ENSAPLT00000004725","GO:0000122(negative regulation of transcription by RNA polymerase II);GO:0001540(amyloid-beta binding);GO:0001954(positive regulation of cell-matrix adhesion);GO:0005041(low-density lipoprotein particle receptor activity);GO:0005044(scavenger receptor activity);GO:0005623(cell);GO:0005794(Golgi apparatus);GO:0005886(plasma membrane);GO:0006898(receptor-mediated endocytosis);GO:0006910(phagocytosis, recognition);GO:0006955(immune response);GO:0007166(cell surface receptor signaling pathway);GO:0007204(positive regulation of cytosolic calcium ion concentration);GO:0007263(nitric oxide mediated signal transduction);GO:0008035(high-density lipoprotein particle binding);GO:0008289(lipid binding);GO:0009617(response to bacterium);GO:0009897(external side of plasma membrane);GO:0009986(cell surface);GO:0010628(positive regulation of gene expression);GO:0010629(negative regulation of gene expression);GO:0010744(positive regulation of macrophage derived foam cell differentiation);GO:0010886(positive regulation of cholesterol storage);GO:0010942(positive regulation of cell death);GO:0016020(membrane);GO:0019915(lipid storage);GO:0019934(cGMP-mediated signaling);GO:0030169(low-density lipoprotein particle binding);GO:0030194(positive regulation of blood coagulation);GO:0030299(intestinal cholesterol absorption);GO:0030301(cholesterol transport);GO:0031526(brush border membrane);GO:0031623(receptor internalization);GO:0032735(positive regulation of interleukin-12 production);GO:0032755(positive regulation of interleukin-6 production);GO:0032760(positive regulation of tumor necrosis factor production);GO:0033993(response to lipid);GO:0034121(regulation of toll-like receptor signaling pathway);GO:0034197(triglyceride transport);GO:0034381(plasma lipoprotein particle clearance);GO:0034383(low-density lipoprotein particle clearance);GO:0035325(Toll-like receptor binding);GO:0035634(response to stilbenoid);GO:0042308(negative regulation of protein import into nucleus);GO:0042953(lipoprotein transport);GO:0043123(positive regulation of I-kappaB kinase/NF-kappaB signaling);GO:0043235(receptor complex);GO:0043277(apoptotic cell clearance);GO:0043410(positive regulation of MAPK cascade);GO:0043497(regulation of protein heterodimerization activity);GO:0044130(negative regulation of growth of symbiont in host);GO:0044539(long-chain fatty acid import into cell);GO:0044877(protein-containing complex binding);GO:0045121(membrane raft);GO:0045177(apical part of cell);GO:0045429(positive regulation of nitric oxide biosynthetic process);GO:0050702(interleukin-1 beta secretion);GO:0050731(positive regulation of peptidyl-tyrosine phosphorylation);GO:0050830(defense response to Gram-positive bacterium);GO:0050892(intestinal absorption);GO:0050909(sensory perception of taste);GO:0051092(positive regulation of NF-kappaB transcription factor activity);GO:0055096(low-density lipoprotein particle mediated signaling);GO:0060100(positive regulation of phagocytosis, engulfment);GO:0060907(positive regulation of macrophage cytokine production);GO:0070374(positive regulation of ERK1 and ERK2 cascade);GO:0070508(cholesterol import);GO:0070542(response to fatty acid);GO:0070543(response to linoleic acid);GO:0070892(lipoteichoic acid receptor activity);GO:0071221(cellular response to bacterial lipopeptide);GO:0071222(cellular response to lipopolysaccharide);GO:0071223(cellular response to lipoteichoic acid);GO:0071404(cellular response to low-density lipoprotein particle stimulus);GO:0071447(cellular response to hydroperoxide);GO:0071726(cellular response to diacyl bacterial lipopeptide);GO:0071813(lipoprotein particle binding);GO:0097009(energy homeostasis);GO:0098900(regulation of action potential);GO:0120162(positive regulation of cold-induced thermogenesis);GO:0140052(cellular response to oxidised low-density lipoprotein particle stimulus);GO:0150024(oxidised low-density lipoprotein particle clearance);GO:0150025(oxidised low-density lipoprotein particle receptor activity);GO:0150094(amyloid-beta clearance by cellular catabolic process);GO:1900227(positive regulation of NLRP3 inflammasome complex assembly);GO:1903428(positive regulation of reactive oxygen species biosynthetic process);GO:1904646(cellular response to amyloid-beta);GO:1990000(amyloid fibril formation);GO:2000121(regulation of removal of superoxide radicals);GO:2000334(positive regulation of blood microparticle formation);GO:2000379(positive regulation of reactive oxygen species metabolic process)","04512(ECM-receptor interaction);04145(Phagosome);04920(Adipocytokine signaling pathway);03320(PPAR signaling pathway)","K06259","NA","CD36 molecule [Source:HGNC Symbol;Acc:HGNC:1663]","NA",{"v":28.067501,"d":"28.07"},{"v":14.441532,"d":"14.44"},{"v":15.253199,"d":"15.25"},{"v":21.515118,"d":"21.52"},{"v":30.019709,"d":"30.02"},{"v":14.757607,"d":"14.76"},{"v":23.47076,"d":"23.47"},{"v":19.004581,"d":"19.00"},{"v":100.680397,"d":"100.68"},{"v":67.989296,"d":"67.99"},{"v":154.11084,"d":"154.11"},{"v":150.386963,"d":"150.39"},{"v":128.588623,"d":"128.59"},{"v":100.154442,"d":"100.15"},{"v":120.312584,"d":"120.31"},{"v":80.290138,"d":"80.29"},{"v":0.18451806764156,"d":"0.18"},{"v":-2.43816600586095,"d":"-2.44"},{"v":6.50120684220871e-50,"d":"0.00"},{"v":7.02604385290785e-48,"d":"0.00"},"down","yes"]
["ENSAPLG00000003050","DUSP26","ENSAPLT00000003089","GO:0000122(negative regulation of transcription by RNA polymerase II);GO:0001102(RNA polymerase II activating transcription factor binding);GO:0002039(p53 binding);GO:0004647(phosphoserine phosphatase activity);GO:0004721(phosphoprotein phosphatase activity);GO:0004725(protein tyrosine phosphatase activity);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005794(Golgi apparatus);GO:0006470(protein dephosphorylation);GO:0008138(protein tyrosine/serine/threonine phosphatase activity);GO:0016311(dephosphorylation);GO:0016791(phosphatase activity);GO:0044387(negative regulation of protein kinase activity by regulation of protein phosphorylation);GO:0045785(positive regulation of cell adhesion);GO:0070373(negative regulation of ERK1 and ERK2 cascade);GO:1902310(positive regulation of peptidyl-serine dephosphorylation)","NA","NA","NA","dual specificity phosphatase 26 [Source:HGNC Symbol;Acc:HGNC:28161]","NA",{"v":106.794884,"d":"106.79"},{"v":95.77597,"d":"95.78"},{"v":93.238724,"d":"93.24"},{"v":74.666763,"d":"74.67"},{"v":95.664375,"d":"95.66"},{"v":107.946297,"d":"107.95"},{"v":103.13623,"d":"103.14"},{"v":103.363503,"d":"103.36"},{"v":225.619659,"d":"225.62"},{"v":289.612823,"d":"289.61"},{"v":281.046234,"d":"281.05"},{"v":328.383911,"d":"328.38"},{"v":247.399918,"d":"247.40"},{"v":304.882294,"d":"304.88"},{"v":233.378052,"d":"233.38"},{"v":291.74176,"d":"291.74"},{"v":0.354479486170181,"d":"0.35"},{"v":-1.49622595418385,"d":"-1.50"},{"v":8.78230535947054e-50,"d":"0.00"},{"v":9.39344516541308e-48,"d":"0.00"},"down","yes"]
["ENSAPLG00000017697","ENSAPLG00000017697","ENSAPLT00000026122","NA","NA","NA","NA",null,"NA",{"v":4.285644,"d":"4.29"},{"v":6.240268,"d":"6.24"},{"v":24.712473,"d":"24.71"},{"v":46.934158,"d":"46.93"},{"v":8.111968,"d":"8.11"},{"v":7.091892,"d":"7.09"},{"v":10.870636,"d":"10.87"},{"v":27.661823,"d":"27.66"},{"v":0.05315,"d":"0.05"},{"v":0.0001,"d":"0.00"},{"v":0.0001,"d":"0.00"},{"v":0.0001,"d":"0.00"},{"v":0.0001,"d":"0.00"},{"v":0.0001,"d":"0.00"},{"v":0.0001,"d":"0.00"},{"v":0.0001,"d":"0.00"},{"v":2523.84144846797,"d":"2523.84"},{"v":11.3014055655476,"d":"11.30"},{"v":1.29133305709081e-49,"d":"0.00"},{"v":1.36710004768542e-47,"d":"0.00"},"up","yes"]
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["ENSAPLG00000028023","LHFPL5","ENSAPLT00000041681","GO:0005886(plasma membrane);GO:0007605(sensory perception of sound);GO:0016324(apical plasma membrane);GO:0032421(stereocilium bundle);GO:0032426(stereocilium tip);GO:0050910(detection of mechanical stimulus involved in sensory perception of sound);GO:0060088(auditory receptor cell stereocilium organization)","NA","NA","NA","LHFPL tetraspan subfamily member 5 [Source:HGNC Symbol;Acc:HGNC:21253]","NA",{"v":2.092003,"d":"2.09"},{"v":2.906174,"d":"2.91"},{"v":1.724621,"d":"1.72"},{"v":1.614385,"d":"1.61"},{"v":3.291388,"d":"3.29"},{"v":2.535699,"d":"2.54"},{"v":1.274232,"d":"1.27"},{"v":2.334095,"d":"2.33"},{"v":12.792041,"d":"12.79"},{"v":32.232533,"d":"32.23"},{"v":12.892811,"d":"12.89"},{"v":17.858162,"d":"17.86"},{"v":16.173618,"d":"16.17"},{"v":20.698587,"d":"20.70"},{"v":21.730272,"d":"21.73"},{"v":30.940582,"d":"30.94"},{"v":0.107505122563155,"d":"0.11"},{"v":-3.21752268976671,"d":"-3.22"},{"v":3.28284426059981e-49,"d":"0.00"},{"v":3.4059509203723e-47,"d":"0.00"},"down","yes"]
["ENSAPLG00000017296","FOXO6","ENSAPLT00000029206","GO:0000981(DNA-binding transcription factor activity, RNA polymerase II-specific);GO:0003700(DNA-binding transcription factor activity);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0006355(regulation of transcription, DNA-templated);GO:0006357(regulation of transcription by RNA polymerase II);GO:0007613(memory);GO:0043565(sequence-specific DNA binding);GO:0060999(positive regulation of dendritic spine development)","04068(FoxO signaling pathway)","K17847","NA","forkhead box O6 [Source:HGNC Symbol;Acc:HGNC:24814]","NA",{"v":2.510847,"d":"2.51"},{"v":1.208951,"d":"1.21"},{"v":2.020605,"d":"2.02"},{"v":2.267314,"d":"2.27"},{"v":3.692213,"d":"3.69"},{"v":3.590223,"d":"3.59"},{"v":1.849707,"d":"1.85"},{"v":3.288916,"d":"3.29"},{"v":10.817435,"d":"10.82"},{"v":13.358768,"d":"13.36"},{"v":11.317954,"d":"11.32"},{"v":17.334785,"d":"17.33"},{"v":13.606813,"d":"13.61"},{"v":13.498752,"d":"13.50"},{"v":15.433778,"d":"15.43"},{"v":11.47527,"d":"11.48"},{"v":0.191202698188019,"d":"0.19"},{"v":-2.38682521259899,"d":"-2.39"},{"v":4.17307710794016e-49,"d":"0.00"},{"v":4.28670049454249e-47,"d":"0.00"},"down","yes"]
["ENSAPLG00000016359","CTNND2","ENSAPLT00000017073","GO:0005515(protein binding);GO:0008013(beta-catenin binding);GO:0043204(perikaryon);GO:0050808(synapse organization);GO:0060828(regulation of canonical Wnt signaling pathway);GO:0060997(dendritic spine morphogenesis);GO:0098609(cell-cell adhesion)","04520(Adherens junction)","K05690","NA","catenin delta 2 [Source:HGNC Symbol;Acc:HGNC:2516]","NA",{"v":15.697272,"d":"15.70"},{"v":16.091522,"d":"16.09"},{"v":18.935398,"d":"18.94"},{"v":20.093435,"d":"20.09"},{"v":17.696918,"d":"17.70"},{"v":18.443989,"d":"18.44"},{"v":17.532663,"d":"17.53"},{"v":16.788336,"d":"16.79"},{"v":3.398824,"d":"3.40"},{"v":2.698426,"d":"2.70"},{"v":1.81175,"d":"1.81"},{"v":3.848162,"d":"3.85"},{"v":2.968521,"d":"2.97"},{"v":2.160461,"d":"2.16"},{"v":2.715701,"d":"2.72"},{"v":2.97279,"d":"2.97"},{"v":6.25833077699817,"d":"6.26"},{"v":2.64577791260943,"d":"2.65"},{"v":2.40501814272784e-48,"d":"0.00"},{"v":2.44628070890209e-46,"d":"0.00"},"up","yes"]
["ENSAPLG00000008932","SHCBP1","ENSAPLT00000009311","NA","NA","NA","NA","SHC binding and spindle associated 1 [Source:HGNC Symbol;Acc:HGNC:29547]","NA",{"v":7.485532,"d":"7.49"},{"v":6.881591,"d":"6.88"},{"v":8.570168,"d":"8.57"},{"v":10.140914,"d":"10.14"},{"v":7.705386,"d":"7.71"},{"v":7.70704,"d":"7.71"},{"v":6.130343,"d":"6.13"},{"v":6.140595,"d":"6.14"},{"v":0.923598,"d":"0.92"},{"v":1.23276,"d":"1.23"},{"v":0.921207,"d":"0.92"},{"v":1.217527,"d":"1.22"},{"v":1.260315,"d":"1.26"},{"v":0.624624,"d":"0.62"},{"v":1.101023,"d":"1.10"},{"v":0.949095,"d":"0.95"},{"v":7.38280303309211,"d":"7.38"},{"v":2.88416866915358,"d":"2.88"},{"v":3.45191396510696e-48,"d":"0.00"},{"v":3.47704926096939e-46,"d":"0.00"},"up","yes"]
["ENSAPLG00000012518","KIF23","ENSAPLT00000004873;ENSAPLT00000013039;ENSAPLT00000004867","GO:0000281(mitotic cytokinesis);GO:0000915(actomyosin contractile ring assembly);GO:0003777(microtubule motor activity);GO:0005524(ATP binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005813(centrosome);GO:0005819(spindle);GO:0007018(microtubule-based movement);GO:0008017(microtubule binding);GO:0030496(midbody);GO:0032467(positive regulation of cytokinesis);GO:0045171(intercellular bridge);GO:0051256(mitotic spindle midzone assembly);GO:0072383(plus-end-directed vesicle transport along microtubule);GO:0072686(mitotic spindle);GO:0097149(centralspindlin complex);GO:0097149(centralspindlin complex)","NA","NA","NA","kinesin family member 23 [Source:HGNC Symbol;Acc:HGNC:6392]","NA",{"v":21.0318641783894,"d":"21.03"},{"v":22.2847140214067,"d":"22.28"},{"v":25.9618067849133,"d":"25.96"},{"v":30.3817735127421,"d":"30.38"},{"v":21.4861896381244,"d":"21.49"},{"v":23.0297918623853,"d":"23.03"},{"v":22.4685541172273,"d":"22.47"},{"v":18.0017202803262,"d":"18.00"},{"v":2.61334203465851,"d":"2.61"},{"v":2.98244860550459,"d":"2.98"},{"v":2.40643428134557,"d":"2.41"},{"v":3.331661,"d":"3.33"},{"v":3.56117983078491,"d":"3.56"},{"v":1.807846,"d":"1.81"},{"v":3.20530548318043,"d":"3.21"},{"v":1.036057,"d":"1.04"},{"v":8.81608082092303,"d":"8.82"},{"v":3.140137449795,"d":"3.14"},{"v":1.08291612367097e-47,"d":"0.00"},{"v":1.08031295991215e-45,"d":"0.00"},"up","yes"]
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["ENSAPLG00000021961","ENSAPLG00000021961","ENSAPLT00000036980","GO:0004672(protein kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation)","NA","NA","NA",null,"NA",{"v":2.683235,"d":"2.68"},{"v":4.574618,"d":"4.57"},{"v":3.260497,"d":"3.26"},{"v":3.670273,"d":"3.67"},{"v":3.272621,"d":"3.27"},{"v":4.542118,"d":"4.54"},{"v":3.136008,"d":"3.14"},{"v":2.898361,"d":"2.90"},{"v":0.636562,"d":"0.64"},{"v":0.342718,"d":"0.34"},{"v":0.261986,"d":"0.26"},{"v":0.616628,"d":"0.62"},{"v":0.540363,"d":"0.54"},{"v":0.362442,"d":"0.36"},{"v":0.564403,"d":"0.56"},{"v":0.534142,"d":"0.53"},{"v":7.26508378324874,"d":"7.27"},{"v":2.8609794355705,"d":"2.86"},{"v":4.71704501568267e-21,"d":"0.00"},{"v":9.53983275588845e-20,"d":"0.00"},"up","yes"]
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ion transport);GO:0006874(cellular calcium ion homeostasis);GO:0006940(regulation of smooth muscle contraction);GO:0007519(skeletal muscle tissue development);GO:0007595(lactation);GO:0008104(protein localization);GO:0008285(negative regulation of cell population proliferation);GO:0009617(response to bacterium);GO:0009968(negative regulation of signal transduction);GO:0010524(positive regulation of calcium ion transport into cytosol);GO:0010608(posttranscriptional regulation of gene expression);GO:0010628(positive regulation of gene expression);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016504(peptidase activator activity);GO:0019065(receptor-mediated endocytosis of virus by host cell);GO:0019217(regulation of fatty acid metabolic process);GO:0019899(enzyme binding);GO:0019901(protein kinase binding);GO:0019915(lipid storage);GO:0030193(regulation of blood coagulation);GO:0030335(positive regulation of cell migration);GO:0030512(negative regulation of transforming growth factor beta receptor signaling pathway);GO:0030674(protein binding, bridging);GO:0030857(negative regulation of epithelial cell differentiation);GO:0030879(mammary gland development);GO:0031295(T cell costimulation);GO:0031397(negative regulation of protein ubiquitination);GO:0031398(positive regulation of protein ubiquitination);GO:0031410(cytoplasmic vesicle);GO:0031623(receptor internalization);GO:0032091(negative regulation of protein binding);GO:0032092(positive regulation of protein binding);GO:0032570(response to progesterone);GO:0032947(protein-containing complex scaffold activity);GO:0032991(protein-containing complex);GO:0033137(negative regulation of peptidyl-serine phosphorylation);GO:0033138(positive regulation of peptidyl-serine phosphorylation);GO:0033484(nitric oxide homeostasis);GO:0034098(VCP-NPL4-UFD1 AAA ATPase complex);GO:0034141(positive regulation of toll-like receptor 3 signaling pathway);GO:0042310(vasoconstriction);GO:0042532(negative regulation of tyrosine phosphorylation of STAT protein);GO:0042632(cholesterol homeostasis);GO:0042802(identical protein binding);GO:0043085(positive regulation of catalytic activity);GO:0043407(negative regulation of MAP kinase activity);GO:0043409(negative regulation of MAPK cascade);GO:0043627(response to estrogen);GO:0044325(ion channel binding);GO:0045019(negative regulation of nitric oxide biosynthetic process);GO:0045121(membrane raft);GO:0045907(positive regulation of vasoconstriction);GO:0046426(negative regulation of receptor signaling pathway via JAK-STAT);GO:0046982(protein heterodimerization activity);GO:0048365(Rac GTPase binding);GO:0048471(perinuclear region of cytoplasm);GO:0048550(negative regulation of pinocytosis);GO:0050998(nitric-oxide synthase binding);GO:0051001(negative regulation of nitric-oxide synthase activity);GO:0051092(positive regulation of NF-kappaB transcription factor activity);GO:0051117(ATPase binding);GO:0051259(protein complex oligomerization);GO:0051260(protein homooligomerization);GO:0051480(regulation of cytosolic calcium ion concentration);GO:0051592(response to calcium ion);GO:0051899(membrane depolarization);GO:0052547(regulation of peptidase activity);GO:0055074(calcium ion homeostasis);GO:0060056(mammary gland involution);GO:0060355(positive regulation of cell adhesion molecule production);GO:0060546(negative regulation of necroptotic process);GO:0061099(negative regulation of protein tyrosine kinase activity);GO:0070320(inward rectifier potassium channel inhibitor activity);GO:0070836(caveola assembly);GO:0071360(cellular response to exogenous dsRNA);GO:0071375(cellular response to peptide hormone stimulus);GO:0071455(cellular response to hyperoxia);GO:0071560(cellular response to transforming growth factor beta stimulus);GO:0072584(caveolin-mediated endocytosis);GO:0086091(regulation of heart rate by cardiac conduction);GO:0086098(angiotensin-activated signaling pathway involved in heart process);GO:0090090(negative regulation of canonical Wnt signaling pathway);GO:0090263(positive regulation of canonical Wnt signaling pathway);GO:0097190(apoptotic signaling pathway);GO:0098903(regulation of membrane repolarization during action potential);GO:0098911(regulation of ventricular cardiac muscle cell action potential);GO:0120162(positive regulation of cold-induced thermogenesis);GO:1900027(regulation of ruffle assembly);GO:1900085(negative regulation of peptidyl-tyrosine autophosphorylation);GO:1901380(negative regulation of potassium ion transmembrane transport);GO:1901844(regulation of cell communication by electrical coupling involved in cardiac conduction);GO:1903598(positive regulation of gap junction assembly);GO:1903609(negative regulation of inward rectifier potassium channel activity);GO:2000286(receptor internalization involved in canonical Wnt signaling pathway);GO:2000535(regulation of entry of bacterium into host cell);GO:2000811(negative regulation of anoikis);GO:2001238(positive regulation of extrinsic apoptotic signaling pathway);GO:2001244(positive regulation of intrinsic apoptotic signaling pathway)","04144(Endocytosis);04510(Focal adhesion)","K06278","NA","caveolin 1 [Source:HGNC Symbol;Acc:HGNC:1527]","NA",{"v":210.458008,"d":"210.46"},{"v":168.875839,"d":"168.88"},{"v":226.032455,"d":"226.03"},{"v":166.359055,"d":"166.36"},{"v":249.0811,"d":"249.08"},{"v":205.654984,"d":"205.65"},{"v":224.170868,"d":"224.17"},{"v":220.983688,"d":"220.98"},{"v":245.763992,"d":"245.76"},{"v":356.489868,"d":"356.49"},{"v":352.574646,"d":"352.57"},{"v":400.044983,"d":"400.04"},{"v":350.287811,"d":"350.29"},{"v":391.557556,"d":"391.56"},{"v":368.085175,"d":"368.09"},{"v":253.812347,"d":"253.81"},{"v":0.614877483460816,"d":"0.61"},{"v":-0.70162911795056,"d":"-0.70"},{"v":8.25947289548101e-19,"d":"0.00"},{"v":1.42582414793037e-17,"d":"0.00"},"down","no"]
["ENSAPLG00000013621","SLC20A2","ENSAPLT00000033376;ENSAPLT00000034266;ENSAPLT00000045431;ENSAPLT00000034498;ENSAPLT00000038790;ENSAPLT00000029143;ENSAPLT00000014229","GO:0005315(inorganic phosphate transmembrane transporter activity);GO:0006817(phosphate ion transport);GO:0016020(membrane);GO:0016020(membrane)","NA","NA","NA","solute carrier family 20 member 2 [Source:HGNC Symbol;Acc:HGNC:10947]","NA",{"v":33.6747685493145,"d":"33.67"},{"v":34.7801264428789,"d":"34.78"},{"v":42.3994976064356,"d":"42.40"},{"v":33.2152749339299,"d":"33.22"},{"v":38.155178237243,"d":"38.16"},{"v":36.2920983156893,"d":"36.29"},{"v":39.3487572376238,"d":"39.35"},{"v":36.5461009053694,"d":"36.55"},{"v":44.5148071839299,"d":"44.51"},{"v":49.0993233143564,"d":"49.10"},{"v":51.7236832983625,"d":"51.72"},{"v":52.4252565790175,"d":"52.43"},{"v":55.3095185769231,"d":"55.31"},{"v":70.9169611384235,"d":"70.92"},{"v":52.5818189586824,"d":"52.58"},{"v":53.5442889362148,"d":"53.54"},{"v":0.684494499937802,"d":"0.68"},{"v":-0.546889145726081,"d":"-0.55"},{"v":9.65313620005386e-19,"d":"0.00"},{"v":1.66364265906244e-17,"d":"0.00"},"down","no"]
["ENSAPLG00000006447","C1orf112","ENSAPLT00000006702;ENSAPLT00000020831","NA","NA","NA","NA","chromosome 1 open reading frame 112 [Source:HGNC Symbol;Acc:HGNC:25565]","NA",{"v":15.280682084922,"d":"15.28"},{"v":14.4544648242634,"d":"14.45"},{"v":15.0570366488735,"d":"15.06"},{"v":13.6519920093588,"d":"13.65"},{"v":13.4334662693241,"d":"13.43"},{"v":14.1606105722704,"d":"14.16"},{"v":15.9123489566724,"d":"15.91"},{"v":16.7796819265165,"d":"16.78"},{"v":4.87037739306759,"d":"4.87"},{"v":5.57566427105719,"d":"5.58"},{"v":2.65594636013865,"d":"2.66"},{"v":3.27299633968804,"d":"3.27"},{"v":5.86461809012132,"d":"5.86"},{"v":4.2749927407279,"d":"4.27"},{"v":4.4316426322357,"d":"4.43"},{"v":3.13802147729636,"d":"3.14"},{"v":3.48343445671147,"d":"3.48"},{"v":1.8005104182174,"d":"1.80"},{"v":1.1129284325707e-18,"d":"0.00"},{"v":1.91486442585756e-17,"d":"0.00"},"up","yes"]
["ENSAPLG00000005106","ORC1","ENSAPLT00000005367","GO:0000784(nuclear chromosome, telomeric region);GO:0000808(origin recognition complex);GO:0003682(chromatin binding);GO:0005524(ATP binding);GO:0005634(nucleus);GO:0005664(nuclear origin of replication recognition complex);GO:0005730(nucleolus);GO:0005829(cytosol);GO:0005886(plasma membrane)","04110(Cell cycle)","K02603","NA","origin recognition complex subunit 1 [Source:HGNC Symbol;Acc:HGNC:8487]","NA",{"v":4.975372,"d":"4.98"},{"v":7.081862,"d":"7.08"},{"v":5.348667,"d":"5.35"},{"v":8.513131,"d":"8.51"},{"v":5.705562,"d":"5.71"},{"v":4.973055,"d":"4.97"},{"v":5.482824,"d":"5.48"},{"v":6.933398,"d":"6.93"},{"v":1.382841,"d":"1.38"},{"v":1.473546,"d":"1.47"},{"v":1.545425,"d":"1.55"},{"v":1.466654,"d":"1.47"},{"v":1.630567,"d":"1.63"},{"v":1.602769,"d":"1.60"},{"v":1.801108,"d":"1.80"},{"v":1.496653,"d":"1.50"},{"v":3.95287083907715,"d":"3.95"},{"v":1.98290081555035,"d":"1.98"},{"v":1.12281075132709e-18,"d":"0.00"},{"v":1.92866912996996e-17,"d":"0.00"},"up","yes"]
["ENSAPLG00000007797","ENSAPLG00000007797","ENSAPLT00000008093","GO:0022857(transmembrane transporter activity);GO:0055085(transmembrane transport)","NA","NA","NA",null,"NA",{"v":5.806714,"d":"5.81"},{"v":6.735832,"d":"6.74"},{"v":6.706396,"d":"6.71"},{"v":3.555519,"d":"3.56"},{"v":4.88032,"d":"4.88"},{"v":7.484871,"d":"7.48"},{"v":7.497273,"d":"7.50"},{"v":8.089798,"d":"8.09"},{"v":10.263713,"d":"10.26"},{"v":13.505019,"d":"13.51"},{"v":13.088309,"d":"13.09"},{"v":15.724483,"d":"15.72"},{"v":14.135741,"d":"14.14"},{"v":11.711694,"d":"11.71"},{"v":14.104193,"d":"14.10"},{"v":12.07497,"d":"12.07"},{"v":0.48520824224337,"d":"0.49"},{"v":-1.04332403712754,"d":"-1.04"},{"v":1.20766165443292e-18,"d":"0.00"},{"v":2.07099002723e-17,"d":"0.00"},"down","yes"]
["ENSAPLG00000012845","ACTR3","ENSAPLT00000039461;ENSAPLT00000031477;ENSAPLT00000019658;ENSAPLT00000013405","GO:0005200(structural constituent of cytoskeleton);GO:0005524(ATP binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005885(Arp2/3 protein complex);GO:0005903(brush border);GO:0005911(cell-cell junction);GO:0007015(actin filament organization);GO:0007163(establishment or maintenance of cell polarity);GO:0008356(asymmetric cell division);GO:0016344(meiotic chromosome movement towards spindle pole);GO:0030027(lamellipodium);GO:0033206(meiotic cytokinesis);GO:0034314(Arp2/3 complex-mediated actin nucleation);GO:0045944(positive regulation of transcription by RNA polymerase II);GO:0051015(actin filament binding);GO:0051321(meiotic cell cycle);GO:0051653(spindle localization);GO:0060271(cilium assembly);GO:0071346(cellular response to interferon-gamma);GO:0071346(cellular response to interferon-gamma)","04530(Tight junction);04530(Tight junction)","K18584","NA","ARP3 actin related protein 3 homolog [Source:HGNC Symbol;Acc:HGNC:170]","NA",{"v":24.5910732240702,"d":"24.59"},{"v":25.2581808400363,"d":"25.26"},{"v":27.8576617949803,"d":"27.86"},{"v":31.5292942679165,"d":"31.53"},{"v":26.9426665430904,"d":"26.94"},{"v":26.6956201802238,"d":"26.70"},{"v":24.6679266985183,"d":"24.67"},{"v":25.4250295022679,"d":"25.43"},{"v":10.265555140006,"d":"10.27"},{"v":10.210645907469,"d":"10.21"},{"v":10.1215792633807,"d":"10.12"},{"v":9.48346388146356,"d":"9.48"},{"v":13.4766929156335,"d":"13.48"},{"v":8.47654877532507,"d":"8.48"},{"v":9.6864898070759,"d":"9.69"},{"v":9.03974409192622,"d":"9.04"},{"v":2.63701776835614,"d":"2.64"},{"v":1.39890729218576,"d":"1.40"},{"v":1.30652685156578e-18,"d":"0.00"},{"v":2.23683433745792e-17,"d":"0.00"},"up","yes"]
["ENSAPLG00000021853","KCNJ11","ENSAPLT00000024349","GO:0005242(inward rectifier potassium channel activity);GO:0005249(voltage-gated potassium channel activity);GO:0005524(ATP binding);GO:0005886(plasma membrane);GO:0006006(glucose metabolic process);GO:0006813(potassium ion transport);GO:0008282(inward rectifying potassium channel);GO:0015272(ATP-activated inward rectifier potassium channel activity);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0030315(T-tubule);GO:0030506(ankyrin binding);GO:0033198(response to ATP);GO:0042391(regulation of membrane potential);GO:0042493(response to drug);GO:0044325(ion channel binding);GO:0046676(negative regulation of insulin secretion);GO:0050796(regulation of insulin secretion);GO:0050877(nervous system process);GO:0071805(potassium ion transmembrane transport);GO:1990573(potassium ion import across plasma membrane)","NA","NA","NA","potassium voltage-gated channel subfamily J member 11 [Source:HGNC Symbol;Acc:HGNC:6257]","NA",{"v":61.032345,"d":"61.03"},{"v":50.489285,"d":"50.49"},{"v":61.112194,"d":"61.11"},{"v":42.953972,"d":"42.95"},{"v":59.672924,"d":"59.67"},{"v":62.957172,"d":"62.96"},{"v":46.963036,"d":"46.96"},{"v":60.638412,"d":"60.64"},{"v":100.114548,"d":"100.11"},{"v":106.774811,"d":"106.77"},{"v":66.404709,"d":"66.40"},{"v":79.799347,"d":"79.80"},{"v":107.617004,"d":"107.62"},{"v":75.602303,"d":"75.60"},{"v":92.776703,"d":"92.78"},{"v":75.955673,"d":"75.96"},{"v":0.632327408934059,"d":"0.63"},{"v":-0.661256338800696,"d":"-0.66"},{"v":1.36878749359146e-18,"d":"0.00"},{"v":2.33956676211062e-17,"d":"0.00"},"down","no"]
["ENSAPLG00000010112","MOGAT1","ENSAPLT00000010541","GO:0003846(2-acylglycerol O-acyltransferase activity);GO:0004144(diacylglycerol O-acyltransferase activity);GO:0005783(endoplasmic reticulum);GO:0006651(diacylglycerol biosynthetic process);GO:0016020(membrane);GO:0016747(transferase activity, transferring acyl groups other than amino-acyl groups)","00561(Glycerolipid metabolism)","K14458","EC:2.3.1.22","monoacylglycerol O-acyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:18210]","NA",{"v":4.930304,"d":"4.93"},{"v":4.930197,"d":"4.93"},{"v":9.116052,"d":"9.12"},{"v":11.366441,"d":"11.37"},{"v":6.335367,"d":"6.34"},{"v":10.683306,"d":"10.68"},{"v":9.214791,"d":"9.21"},{"v":5.158054,"d":"5.16"},{"v":1.063306,"d":"1.06"},{"v":0.208979,"d":"0.21"},{"v":0.230743,"d":"0.23"},{"v":0.076439,"d":"0.08"},{"v":0.087074,"d":"0.09"},{"v":0.654605,"d":"0.65"},{"v":0.079478,"d":"0.08"},{"v":0.097393,"d":"0.10"},{"v":24.713407474809,"d":"24.71"},{"v":4.62722203748805,"d":"4.63"},{"v":1.41579965557759e-18,"d":"0.00"},{"v":2.41594102411471e-17,"d":"0.00"},"up","yes"]
["ENSAPLG00000009387","SPRED2","ENSAPLT00000009778;ENSAPLT00000022119;ENSAPLT00000032972","GO:0000188(inactivation of MAPK activity);GO:0005173(stem cell factor receptor binding);GO:0005886(plasma membrane);GO:0007275(multicellular organism development);GO:0009966(regulation of signal transduction);GO:0010801(negative regulation of peptidyl-threonine phosphorylation);GO:0016020(membrane);GO:0019901(protein kinase binding);GO:0030291(protein serine/threonine kinase inhibitor activity);GO:0031410(cytoplasmic vesicle);GO:0043517(positive regulation of DNA damage response, signal transduction by p53 class mediator);GO:0090311(regulation of protein deacetylation);GO:0090311(regulation of protein deacetylation)","NA","NA","NA","sprouty related EVH1 domain containing 2 [Source:HGNC Symbol;Acc:HGNC:17722]","NA",{"v":24.4377575333333,"d":"24.44"},{"v":14.8476773205479,"d":"14.85"},{"v":28.6253223378995,"d":"28.63"},{"v":30.3128933835616,"d":"30.31"},{"v":30.7679813643836,"d":"30.77"},{"v":27.1836279178082,"d":"27.18"},{"v":30.6697568219178,"d":"30.67"},{"v":26.7373847415525,"d":"26.74"},{"v":9.88606550319635,"d":"9.89"},{"v":9.10603095525114,"d":"9.11"},{"v":7.37217562739726,"d":"7.37"},{"v":8.01290782648402,"d":"8.01"},{"v":8.89271802739726,"d":"8.89"},{"v":6.29061592146119,"d":"6.29"},{"v":6.05818703378996,"d":"6.06"},{"v":6.16353112328767,"d":"6.16"},{"v":3.45701983311096,"d":"3.46"},{"v":1.78952888044403,"d":"1.79"},{"v":1.46076712886263e-18,"d":"0.00"},{"v":2.48858111033659e-17,"d":"0.00"},"up","yes"]
["ENSAPLG00000013579","GPSM2","ENSAPLT00000014192","GO:0000132(establishment of mitotic spindle orientation);GO:0001965(G-protein alpha-subunit binding);GO:0005092(GDP-dissociation inhibitor activity);GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0005813(centrosome);GO:0005829(cytosol);GO:0005938(cell cortex);GO:0007052(mitotic spindle organization);GO:0008022(protein C-terminus binding);GO:0019904(protein domain specific binding);GO:0030695(GTPase regulator activity);GO:0031291(Ran protein signal transduction);GO:0032991(protein-containing complex);GO:0042802(identical protein binding);GO:0043621(protein self-association);GO:0051661(maintenance of centrosome location);GO:0060236(regulation of mitotic spindle organization);GO:0070840(dynein complex binding);GO:0097431(mitotic spindle pole);GO:0097575(lateral cell cortex);GO:0099738(cell cortex region);GO:1904778(positive regulation of protein localization to cell cortex);GO:1905832(positive regulation of spindle assembly)","NA","NA","NA","G protein signaling modulator 2 [Source:HGNC Symbol;Acc:HGNC:29501]","NA",{"v":90.313133,"d":"90.31"},{"v":89.64534,"d":"89.65"},{"v":89.856079,"d":"89.86"},{"v":101.286263,"d":"101.29"},{"v":98.815926,"d":"98.82"},{"v":83.871826,"d":"83.87"},{"v":95.333328,"d":"95.33"},{"v":75.398682,"d":"75.40"},{"v":41.86747,"d":"41.87"},{"v":36.480991,"d":"36.48"},{"v":28.881577,"d":"28.88"},{"v":24.255184,"d":"24.26"},{"v":28.882385,"d":"28.88"},{"v":35.375202,"d":"35.38"},{"v":33.310539,"d":"33.31"},{"v":26.588541,"d":"26.59"},{"v":2.83412307675445,"d":"2.83"},{"v":1.50290241117328,"d":"1.50"},{"v":1.49947217009691e-18,"d":"0.00"},{"v":2.550331764714e-17,"d":"0.00"},"up","yes"]
["ENSAPLG00000015224","ACACB","ENSAPLT00000046874;ENSAPLT00000015957","GO:0003989(acetyl-CoA carboxylase activity);GO:0005524(ATP binding);GO:0005634(nucleus);GO:0005739(mitochondrion);GO:0006084(acetyl-CoA metabolic process);GO:0006633(fatty acid biosynthetic process);GO:0010629(negative regulation of gene expression);GO:0010884(positive regulation of lipid storage);GO:0010906(regulation of glucose metabolic process);GO:0016874(ligase activity);GO:0031667(response to nutrient levels);GO:0031999(negative regulation of fatty acid beta-oxidation);GO:0042802(identical protein binding);GO:0043086(negative regulation of catalytic activity);GO:0046322(negative regulation of fatty acid oxidation);GO:0046872(metal ion binding);GO:0050995(negative regulation of lipid catabolic process);GO:0051289(protein homotetramerization);GO:0060421(positive regulation of heart growth);GO:0097009(energy homeostasis);GO:2001295(malonyl-CoA biosynthetic process);GO:2001295(malonyl-CoA biosynthetic process)","00620(Pyruvate metabolism);00640(Propanoate metabolism);00061(Fatty acid biosynthesis);00254(Aflatoxin biosynthesis);04910(Insulin signaling pathway);04920(Adipocytokine signaling pathway);04920(Adipocytokine signaling pathway)","K01946","EC:6.4.1.2;EC:6.3.4.14","acetyl-CoA carboxylase beta [Source:HGNC Symbol;Acc:HGNC:85]","NA",{"v":26.9419637309176,"d":"26.94"},{"v":12.2721873788923,"d":"12.27"},{"v":28.8234877073574,"d":"28.82"},{"v":18.8418775890052,"d":"18.84"},{"v":24.6723689072747,"d":"24.67"},{"v":29.9216337805181,"d":"29.92"},{"v":25.8609379509507,"d":"25.86"},{"v":25.9557447361532,"d":"25.96"},{"v":57.8593715821163,"d":"57.86"},{"v":49.6382646880683,"d":"49.64"},{"v":53.1379735235602,"d":"53.14"},{"v":41.5712680971342,"d":"41.57"},{"v":39.4064876446679,"d":"39.41"},{"v":90.0609205621383,"d":"90.06"},{"v":53.0498061872417,"d":"53.05"},{"v":44.5744706457702,"d":"44.57"},{"v":0.450246561417613,"d":"0.45"},{"v":-1.15121283673405,"d":"-1.15"},{"v":1.61372265076882e-18,"d":"0.00"},{"v":2.74015916558536e-17,"d":"0.00"},"down","yes"]
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["ENSAPLG00000018085","ENSAPLG00000018085","ENSAPLT00000028840;ENSAPLT00000023768;ENSAPLT00000040076;ENSAPLT00000033115","NA","NA","NA","NA",null,"NA",{"v":8.37962304007239,"d":"8.38"},{"v":11.9609112885212,"d":"11.96"},{"v":10.0586103831437,"d":"10.06"},{"v":17.5945777854188,"d":"17.59"},{"v":10.6230668790072,"d":"10.62"},{"v":6.85212548810755,"d":"6.85"},{"v":7.73897346535677,"d":"7.74"},{"v":7.01072739193382,"d":"7.01"},{"v":2.72434004317477,"d":"2.72"},{"v":2.03684220708376,"d":"2.04"},{"v":1.36721671897622,"d":"1.37"},{"v":2.40371188495346,"d":"2.40"},{"v":3.42964565305067,"d":"3.43"},{"v":1.39900960186143,"d":"1.40"},{"v":2.44299921096174,"d":"2.44"},{"v":2.22850993665977,"d":"2.23"},{"v":4.44861308844865,"d":"4.45"},{"v":2.15335562770008,"d":"2.15"},{"v":1.17966504268149e-17,"d":"0.00"},{"v":1.90639015853901e-16,"d":"0.00"},"up","yes"]
["ENSAPLG00000005590","CD47","ENSAPLT00000046671;ENSAPLT00000029556;ENSAPLT00000017831;ENSAPLT00000005797","GO:0005887(integral component of plasma membrane);GO:0008228(opsonization);GO:0008284(positive regulation of cell population proliferation);GO:0009617(response to bacterium);GO:0009986(cell surface);GO:0022409(positive regulation of cell-cell adhesion);GO:0032649(regulation of interferon-gamma production);GO:0032653(regulation of interleukin-10 production);GO:0032655(regulation of interleukin-12 production);GO:0032675(regulation of interleukin-6 production);GO:0032680(regulation of tumor necrosis factor production);GO:0045428(regulation of nitric oxide biosynthetic process);GO:0050729(positive regulation of inflammatory response);GO:0050766(positive regulation of phagocytosis);GO:0050870(positive regulation of T cell activation);GO:0070053(thrombospondin receptor activity);GO:0070062(extracellular exosome);GO:0071349(cellular response to interleukin-12);GO:0098632(cell-cell adhesion mediator activity);GO:0098632(cell-cell adhesion mediator activity)","04512(ECM-receptor interaction);04512(ECM-receptor interaction)","K06266","NA","CD47 molecule [Source:HGNC Symbol;Acc:HGNC:1682]","NA",{"v":39.81808112827,"d":"39.82"},{"v":34.1114190042194,"d":"34.11"},{"v":35.9565032447257,"d":"35.96"},{"v":49.3498181189873,"d":"49.35"},{"v":40.4108442379747,"d":"40.41"},{"v":37.2470972075949,"d":"37.25"},{"v":38.969496021097,"d":"38.97"},{"v":32.6055287341772,"d":"32.61"},{"v":11.499148464135,"d":"11.50"},{"v":16.6793563949367,"d":"16.68"},{"v":12.3900717704641,"d":"12.39"},{"v":14.5251606582278,"d":"14.53"},{"v":13.0940982751055,"d":"13.09"},{"v":8.92569996624473,"d":"8.93"},{"v":11.9182501417722,"d":"11.92"},{"v":10.8180273966245,"d":"10.82"},{"v":3.08932764339262,"d":"3.09"},{"v":1.62729288632033,"d":"1.63"},{"v":1.26524202958442e-17,"d":"0.00"},{"v":2.04150638521592e-16,"d":"0.00"},"up","yes"]
["ENSAPLG00000009561","SCARB2","ENSAPLT00000024405;ENSAPLT00000010020","GO:0001786(phosphatidylserine binding);GO:0005044(scavenger receptor activity);GO:0005548(phospholipid transporter activity);GO:0005764(lysosome);GO:0005765(lysosomal membrane);GO:0005886(plasma membrane);GO:0006622(protein targeting to lysosome);GO:0006898(receptor-mediated endocytosis);GO:0008565(protein transporter activity);GO:0015485(cholesterol binding);GO:0015917(aminophospholipid transport);GO:0016020(membrane);GO:0019899(enzyme binding);GO:0030666(endocytic vesicle membrane);GO:0031210(phosphatidylcholine binding);GO:0042803(protein homodimerization activity);GO:0043202(lysosomal lumen);GO:0043471(regulation of cellular carbohydrate catabolic process);GO:0051087(chaperone binding);GO:1905123(regulation of glucosylceramidase activity);GO:1905123(regulation of glucosylceramidase activity)","04142(Lysosome);04142(Lysosome)","K12384","NA","scavenger receptor class B member 2 [Source:HGNC Symbol;Acc:HGNC:1665]","NA",{"v":56.9073173075644,"d":"56.91"},{"v":28.2341532730673,"d":"28.23"},{"v":39.0588308998338,"d":"39.06"},{"v":40.5057392680798,"d":"40.51"},{"v":61.1003896300914,"d":"61.10"},{"v":54.68536340399,"d":"54.69"},{"v":47.9081257003325,"d":"47.91"},{"v":58.7296434102244,"d":"58.73"},{"v":88.783918638404,"d":"88.78"},{"v":92.6813685320033,"d":"92.68"},{"v":75.2414930361596,"d":"75.24"},{"v":107.161619376559,"d":"107.16"},{"v":73.2207887963425,"d":"73.22"},{"v":77.6050226359102,"d":"77.61"},{"v":76.3243893586866,"d":"76.32"},{"v":93.7464683798836,"d":"93.75"},{"v":0.565346540818203,"d":"0.57"},{"v":-0.822792626544661,"d":"-0.82"},{"v":1.33160854030508e-17,"d":"0.00"},{"v":2.14525444187348e-16,"d":"0.00"},"down","no"]
["ENSAPLG00000010339","ECT2","ENSAPLT00000010847;ENSAPLT00000019315","GO:0000281(mitotic cytokinesis);GO:0000902(cell morphogenesis);GO:0005085(guanyl-nucleotide exchange factor activity);GO:0005089(Rho guanyl-nucleotide exchange factor activity);GO:0005096(GTPase activator activity);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005911(cell-cell junction);GO:0005923(bicellular tight junction);GO:0017048(Rho GTPase binding);GO:0030496(midbody);GO:0032147(activation of protein kinase activity);GO:0032154(cleavage furrow);GO:0032467(positive regulation of cytokinesis);GO:0035023(regulation of Rho protein signal transduction);GO:0035556(intracellular signal transduction);GO:0042307(positive regulation of protein import into nucleus);GO:0042803(protein homodimerization activity);GO:0043065(positive regulation of apoptotic process);GO:0043547(positive regulation of GTPase activity);GO:0045666(positive regulation of neuron differentiation);GO:0045859(regulation of protein kinase activity);GO:0051260(protein homooligomerization);GO:0051988(regulation of attachment of spindle microtubules to kinetochore);GO:0070301(cellular response to hydrogen peroxide);GO:0070830(bicellular tight junction assembly);GO:0071277(cellular response to calcium ion);GO:0071479(cellular response to ionizing radiation);GO:0072686(mitotic spindle);GO:0090630(activation of GTPase activity);GO:0097149(centralspindlin complex);GO:2000431(regulation of cytokinesis, actomyosin contractile ring assembly);GO:2000431(regulation of cytokinesis, actomyosin contractile ring assembly)","NA","NA","NA","epithelial cell transforming 2 [Source:HGNC Symbol;Acc:HGNC:3155]","NA",{"v":3.80941986597938,"d":"3.81"},{"v":6.86072092268041,"d":"6.86"},{"v":6.16680988530928,"d":"6.17"},{"v":11.0262656662371,"d":"11.03"},{"v":4.279091,"d":"4.28"},{"v":5.97249539561856,"d":"5.97"},{"v":5.12746,"d":"5.13"},{"v":5.12796492525773,"d":"5.13"},{"v":0.636234,"d":"0.64"},{"v":0.473865,"d":"0.47"},{"v":1.173355,"d":"1.17"},{"v":0.936609896907216,"d":"0.94"},{"v":1.21988657603093,"d":"1.22"},{"v":1.153226,"d":"1.15"},{"v":1.51038,"d":"1.51"},{"v":0.526314,"d":"0.53"},{"v":6.3395869998899,"d":"6.34"},{"v":2.66438885730184,"d":"2.66"},{"v":1.33394917012805e-17,"d":"0.00"},{"v":2.14569343257031e-16,"d":"0.00"},"up","yes"]
["ENSAPLG00000021120","IMPA2","ENSAPLT00000029183","GO:0005737(cytoplasm);GO:0008934(inositol monophosphate 1-phosphatase activity);GO:0042803(protein homodimerization activity);GO:0046854(phosphatidylinositol phosphorylation);GO:0046855(inositol phosphate dephosphorylation)","00562(Inositol phosphate metabolism);04070(Phosphatidylinositol signaling system)","K01092","EC:3.1.3.25","inositol monophosphatase 2 [Source:HGNC Symbol;Acc:HGNC:6051]","NA",{"v":86.12088,"d":"86.12"},{"v":47.297703,"d":"47.30"},{"v":67.879364,"d":"67.88"},{"v":70.1744,"d":"70.17"},{"v":72.716072,"d":"72.72"},{"v":75.101784,"d":"75.10"},{"v":67.192322,"d":"67.19"},{"v":79.398567,"d":"79.40"},{"v":113.231331,"d":"113.23"},{"v":98.218193,"d":"98.22"},{"v":87.983902,"d":"87.98"},{"v":133.972763,"d":"133.97"},{"v":117.159447,"d":"117.16"},{"v":107.288124,"d":"107.29"},{"v":107.085365,"d":"107.09"},{"v":89.749985,"d":"89.75"},{"v":0.662089975616982,"d":"0.66"},{"v":-0.594900807528818,"d":"-0.59"},{"v":1.35064050621106e-17,"d":"0.00"},{"v":2.16917883156962e-16,"d":"0.00"},"down","no"]
["ENSAPLG00000007779","PHACTR2","ENSAPLT00000038921;ENSAPLT00000008090;ENSAPLT00000035843;ENSAPLT00000045219;ENSAPLT00000036586;ENSAPLT00000031798;ENSAPLT00000036709","NA","NA","NA","NA","phosphatase and actin regulator 2 [Source:HGNC Symbol;Acc:HGNC:20956]","NA",{"v":29.3515860433222,"d":"29.35"},{"v":27.1935740171751,"d":"27.19"},{"v":30.9435404165599,"d":"30.94"},{"v":43.3903755298641,"d":"43.39"},{"v":33.5497627418611,"d":"33.55"},{"v":33.2826481402205,"d":"33.28"},{"v":31.5010307690336,"d":"31.50"},{"v":31.7926674029736,"d":"31.79"},{"v":13.0723476734171,"d":"13.07"},{"v":11.7613019364266,"d":"11.76"},{"v":13.1587745788259,"d":"13.16"},{"v":13.3342581058703,"d":"13.33"},{"v":13.5981336444501,"d":"13.60"},{"v":11.7823826208664,"d":"11.78"},{"v":12.5791801622661,"d":"12.58"},{"v":8.88856991540631,"d":"8.89"},{"v":2.658572158002,"d":"2.66"},{"v":1.4106516240581,"d":"1.41"},{"v":1.38259425092063e-17,"d":"0.00"},{"v":2.21706574239591e-16,"d":"0.00"},"up","yes"]
["ENSAPLG00000016177","PANX1","ENSAPLT00000016873;ENSAPLT00000030737","GO:0002931(response to ischemia);GO:0003779(actin binding);GO:0005102(signaling receptor binding);GO:0005262(calcium channel activity);GO:0005783(endoplasmic reticulum);GO:0005886(plasma membrane);GO:0006812(cation transport);GO:0006816(calcium ion transport);GO:0015267(channel activity);GO:0022840(leak channel activity);GO:0032059(bleb);GO:0033198(response to ATP);GO:0034214(protein hexamerization);GO:0050715(positive regulation of cytokine secretion);GO:0050716(positive regulation of interleukin-1 secretion);GO:0050717(positive regulation of interleukin-1 alpha secretion);GO:0050718(positive regulation of interleukin-1 beta secretion);GO:0051015(actin filament binding);GO:0055077(gap junction hemi-channel activity);GO:0055085(transmembrane transport);GO:0055085(transmembrane transport)","04621(NOD-like receptor signaling pathway);04621(NOD-like receptor signaling pathway)","K03443","NA","pannexin 1 [Source:HGNC Symbol;Acc:HGNC:8599]","NA",{"v":6.157456,"d":"6.16"},{"v":3.893707,"d":"3.89"},{"v":5.106594,"d":"5.11"},{"v":6.218308,"d":"6.22"},{"v":4.800905,"d":"4.80"},{"v":5.049464,"d":"5.05"},{"v":4.86482,"d":"4.86"},{"v":4.051857,"d":"4.05"},{"v":1.021285,"d":"1.02"},{"v":0.454563,"d":"0.45"},{"v":0.861932,"d":"0.86"},{"v":0.715935,"d":"0.72"},{"v":0.864323,"d":"0.86"},{"v":0.728227,"d":"0.73"},{"v":1.430295,"d":"1.43"},{"v":0.324743,"d":"0.32"},{"v":6.27108434017262,"d":"6.27"},{"v":2.64871492260199,"d":"2.65"},{"v":1.58341606772843e-17,"d":"0.00"},{"v":2.53517618868557e-16,"d":"0.00"},"up","yes"]
["ENSAPLG00000010959","SESN2","ENSAPLT00000013868;ENSAPLT00000024063;ENSAPLT00000011406","GO:0001932(regulation of protein phosphorylation);GO:0005092(GDP-dissociation inhibitor activity);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0006111(regulation of gluconeogenesis);GO:0006635(fatty acid beta-oxidation);GO:0007005(mitochondrion organization);GO:0009749(response to glucose);GO:0016239(positive regulation of macroautophagy);GO:0016684(oxidoreductase activity, acting on peroxide as acceptor);GO:0030308(negative regulation of cell growth);GO:0030330(DNA damage response, signal transduction by p53 class mediator);GO:0031588(nucleotide-activated protein kinase complex);GO:0031932(TORC2 complex);GO:0032042(mitochondrial DNA metabolic process);GO:0032542(sulfiredoxin activity);GO:0032868(response to insulin);GO:0034198(cellular response to amino acid starvation);GO:0034599(cellular response to oxidative stress);GO:0036091(positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress);GO:0042149(cellular response to glucose starvation);GO:0042593(glucose homeostasis);GO:0043491(protein kinase B signaling);GO:0046323(glucose import);GO:0061700(GATOR2 complex);GO:0070328(triglyceride homeostasis);GO:0070728(leucine binding);GO:0071230(cellular response to amino acid stimulus);GO:0071233(cellular response to leucine);GO:0072593(reactive oxygen species metabolic process);GO:0098869(cellular oxidant detoxification);GO:1900182(positive regulation of protein localization to nucleus);GO:1901031(regulation of response to reactive oxygen species);GO:1902010(negative regulation of translation in response to endoplasmic reticulum stress);GO:1904262(negative regulation of TORC1 signaling);GO:1904504(positive regulation of lipophagy);GO:1990253(cellular response to leucine starvation);GO:1990316(Atg1/ULK1 kinase complex);GO:2000479(regulation of cAMP-dependent protein kinase activity);GO:2000479(regulation of cAMP-dependent protein kinase activity)","04150(mTOR signaling pathway);04115(p53 signaling pathway);04115(p53 signaling pathway)","K20394","NA","sestrin 2 [Source:HGNC Symbol;Acc:HGNC:20746]","NA",{"v":3.09139220496894,"d":"3.09"},{"v":0.700709751552795,"d":"0.70"},{"v":4.30837564022934,"d":"4.31"},{"v":5.76481968944099,"d":"5.76"},{"v":3.27487369565217,"d":"3.27"},{"v":3.96059250358337,"d":"3.96"},{"v":2.25239357142857,"d":"2.25"},{"v":2.79568125895843,"d":"2.80"},{"v":8.22704380076445,"d":"8.23"},{"v":10.4583616340182,"d":"10.46"},{"v":10.8133143311037,"d":"10.81"},{"v":11.7822016722408,"d":"11.78"},{"v":11.9554481820354,"d":"11.96"},{"v":20.6347010272336,"d":"20.63"},{"v":7.69486587434305,"d":"7.69"},{"v":10.9870754419494,"d":"10.99"},{"v":0.282528226375535,"d":"0.28"},{"v":-1.82353308570381,"d":"-1.82"},{"v":1.65342996314909e-17,"d":"0.00"},{"v":2.6431950489479e-16,"d":"0.00"},"down","yes"]
["ENSAPLG00000003145","SREBF2","ENSAPLT00000003287","GO:0000122(negative regulation of transcription by RNA polymerase II);GO:0000978(RNA polymerase II proximal promoter sequence-specific DNA binding);GO:0001227(DNA-binding transcription repressor activity, RNA polymerase II-specific);GO:0003677(DNA binding);GO:0003700(DNA-binding transcription factor activity);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0005739(mitochondrion);GO:0005783(endoplasmic reticulum);GO:0006355(regulation of transcription, DNA-templated);GO:0008022(protein C-terminus binding);GO:0009267(cellular response to starvation);GO:0010886(positive regulation of cholesterol storage);GO:0016020(membrane);GO:0032937(SREBP-SCAP-Insig complex);GO:0042632(cholesterol homeostasis);GO:0043231(intracellular membrane-bounded organelle);GO:0044212(transcription regulatory region DNA binding);GO:0045944(positive regulation of transcription by RNA polymerase II);GO:0046983(protein dimerization activity);GO:0070888(E-box binding);GO:0071404(cellular response to low-density lipoprotein particle stimulus);GO:0072368(regulation of lipid transport by negative regulation of transcription from RNA polymerase II promoter);GO:0090370(negative regulation of cholesterol efflux);GO:1902895(positive regulation of pri-miRNA transcription by RNA polymerase II)","NA","NA","NA","sterol regulatory element binding transcription factor 2 [Source:HGNC Symbol;Acc:HGNC:11290]","NA",{"v":26.940252,"d":"26.94"},{"v":27.059071,"d":"27.06"},{"v":28.054054,"d":"28.05"},{"v":19.929947,"d":"19.93"},{"v":22.414663,"d":"22.41"},{"v":23.580065,"d":"23.58"},{"v":28.111692,"d":"28.11"},{"v":26.32922,"d":"26.33"},{"v":8.622509,"d":"8.62"},{"v":10.04899,"d":"10.05"},{"v":6.644236,"d":"6.64"},{"v":7.602758,"d":"7.60"},{"v":7.010623,"d":"7.01"},{"v":8.651113,"d":"8.65"},{"v":10.364152,"d":"10.36"},{"v":9.517533,"d":"9.52"},{"v":2.95666527815743,"d":"2.96"},{"v":1.56397092628685,"d":"1.56"},{"v":1.67848793059202e-17,"d":"0.00"},{"v":2.67912496613726e-16,"d":"0.00"},"up","yes"]
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["ENSAPLG00000010161","ARRDC4","ENSAPLT00000010597","GO:0005768(endosome);GO:0005886(plasma membrane);GO:0015031(protein transport);GO:0016567(protein ubiquitination);GO:0051443(positive regulation of ubiquitin-protein transferase activity);GO:0140112(extracellular vesicle biogenesis);GO:1903561(extracellular vesicle);GO:1990756(protein binding, bridging involved in substrate recognition for ubiquitination)","04621(NOD-like receptor signaling pathway)","K20910","NA","arrestin domain containing 4 [Source:HGNC Symbol;Acc:HGNC:28087]","NA",{"v":3.078101,"d":"3.08"},{"v":4.092447,"d":"4.09"},{"v":3.260338,"d":"3.26"},{"v":5.088269,"d":"5.09"},{"v":3.972587,"d":"3.97"},{"v":4.444304,"d":"4.44"},{"v":3.700215,"d":"3.70"},{"v":3.498926,"d":"3.50"},{"v":4.672422,"d":"4.67"},{"v":7.952511,"d":"7.95"},{"v":7.247261,"d":"7.25"},{"v":6.030211,"d":"6.03"},{"v":11.064376,"d":"11.06"},{"v":5.797225,"d":"5.80"},{"v":9.013359,"d":"9.01"},{"v":6.486492,"d":"6.49"},{"v":0.534382524658469,"d":"0.53"},{"v":-0.904055265220596,"d":"-0.90"},{"v":2.5081453402785e-15,"d":"0.00"},{"v":3.36201652524411e-14,"d":"0.00"},"down","no"]
["ENSAPLG00000012736","SNX7","ENSAPLT00000013273;ENSAPLT00000046166","GO:0035091(phosphatidylinositol binding);GO:0035091(phosphatidylinositol binding)","NA","NA","NA","sorting nexin 7 [Source:HGNC Symbol;Acc:HGNC:14971]","NA",{"v":26.735897854192,"d":"26.74"},{"v":27.3013612454435,"d":"27.30"},{"v":20.9429742345079,"d":"20.94"},{"v":37.1536137144593,"d":"37.15"},{"v":19.6728508040705,"d":"19.67"},{"v":19.5424797861482,"d":"19.54"},{"v":19.7072406312272,"d":"19.71"},{"v":21.5267192718712,"d":"21.53"},{"v":8.16923833900364,"d":"8.17"},{"v":6.00317405710814,"d":"6.00"},{"v":7.34946491798299,"d":"7.35"},{"v":7.66890354586877,"d":"7.67"},{"v":10.8541156130012,"d":"10.85"},{"v":7.30111034204131,"d":"7.30"},{"v":8.07722529890644,"d":"8.08"},{"v":8.47648476427703,"d":"8.48"},{"v":3.01383397220736,"d":"3.01"},{"v":1.59159994312334,"d":"1.59"},{"v":2.52329367132412e-15,"d":"0.00"},{"v":3.37795765677261e-14,"d":"0.00"},"up","yes"]
["ENSAPLG00000006008","MDGA1","ENSAPLT00000047551;ENSAPLT00000006289","GO:0005515(protein binding);GO:0016020(membrane);GO:0046658(anchored component of plasma membrane);GO:0098982(GABA-ergic synapse);GO:0099179(regulation of synaptic membrane adhesion);GO:1905606(regulation of presynapse assembly);GO:1905606(regulation of presynapse assembly)","04512(ECM-receptor interaction);04512(ECM-receptor interaction)","K06255","NA","MAM domain containing glycosylphosphatidylinositol anchor 1 [Source:HGNC Symbol;Acc:HGNC:19267]","NA",{"v":2.281486354808,"d":"2.28"},{"v":1.6712919301809,"d":"1.67"},{"v":2.5345519136782,"d":"2.53"},{"v":2.50251324658838,"d":"2.50"},{"v":1.16577444620755,"d":"1.17"},{"v":1.75815553157728,"d":"1.76"},{"v":1.87784205395113,"d":"1.88"},{"v":1.52176384893685,"d":"1.52"},{"v":0.0708542456363059,"d":"0.07"},{"v":0.0755717423040305,"d":"0.08"},{"v":0.207661649000317,"d":"0.21"},{"v":0.123707569660425,"d":"0.12"},{"v":0.218867699143129,"d":"0.22"},{"v":0.0418069184385909,"d":"0.04"},{"v":0.102309212313551,"d":"0.10"},{"v":0.440771638210092,"d":"0.44"},{"v":11.9491016845167,"d":"11.95"},{"v":3.57883025752794,"d":"3.58"},{"v":2.53048002822369e-15,"d":"0.00"},{"v":3.38321266660061e-14,"d":"0.00"},"up","yes"]
["ENSAPLG00000019694","ENSAPLG00000019694","ENSAPLT00000030541","GO:0000785(chromatin);GO:0005634(nucleus);GO:0031492(nucleosomal DNA binding)","NA","NA","NA",null,"NA",{"v":203.943451,"d":"203.94"},{"v":252.491089,"d":"252.49"},{"v":197.66217,"d":"197.66"},{"v":244.875397,"d":"244.88"},{"v":171.578476,"d":"171.58"},{"v":145.813828,"d":"145.81"},{"v":159.968552,"d":"159.97"},{"v":181.074753,"d":"181.07"},{"v":75.148582,"d":"75.15"},{"v":56.082245,"d":"56.08"},{"v":59.475777,"d":"59.48"},{"v":72.962059,"d":"72.96"},{"v":70.879173,"d":"70.88"},{"v":51.217392,"d":"51.22"},{"v":72.575043,"d":"72.58"},{"v":55.259487,"d":"55.26"},{"v":3.03233732442686,"d":"3.03"},{"v":1.60043025126903,"d":"1.60"},{"v":2.57638719083735e-15,"d":"0.00"},{"v":3.4401566415621e-14,"d":"0.00"},"up","yes"]
["ENSAPLG00000003162","SFRP2","ENSAPLT00000003219;ENSAPLT00000023710","GO:0001569(branching involved in blood vessel morphogenesis);GO:0001756(somitogenesis);GO:0001843(neural tube closure);GO:0002063(chondrocyte development);GO:0003151(outflow tract morphogenesis);GO:0003214(cardiac left ventricle morphogenesis);GO:0005515(protein binding);GO:0005615(extracellular space);GO:0006915(apoptotic process);GO:0008047(enzyme activator activity);GO:0008284(positive regulation of cell population proliferation);GO:0008285(negative regulation of cell population proliferation);GO:0008584(male gonad development);GO:0009952(anterior/posterior pattern specification);GO:0010629(negative regulation of gene expression);GO:0010667(negative regulation of cardiac muscle cell apoptotic process);GO:0010719(negative regulation of epithelial to mesenchymal transition);GO:0010950(positive regulation of endopeptidase activity);GO:0010975(regulation of neuron projection development);GO:0017147(Wnt-protein binding);GO:0021915(neural tube development);GO:0030111(regulation of Wnt signaling pathway);GO:0030178(negative regulation of Wnt signaling pathway);GO:0030199(collagen fibril organization);GO:0030307(positive regulation of cell growth);GO:0030308(negative regulation of cell growth);GO:0030336(negative regulation of cell migration);GO:0030514(negative regulation of BMP signaling pathway);GO:0031668(cellular response to extracellular stimulus);GO:0033138(positive regulation of peptidyl-serine phosphorylation);GO:0036342(post-anal tail morphogenesis);GO:0042127(regulation of cell population proliferation);GO:0042493(response to drug);GO:0042662(negative regulation of mesodermal cell fate specification);GO:0042733(embryonic digit morphogenesis);GO:0042981(regulation of apoptotic process);GO:0043065(positive regulation of apoptotic process);GO:0043154(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process);GO:0043508(negative regulation of JUN kinase activity);GO:0045600(positive regulation of fat cell differentiation);GO:0045669(positive regulation of osteoblast differentiation);GO:0045766(positive regulation of angiogenesis);GO:0045892(negative regulation of transcription, DNA-templated);GO:0045944(positive regulation of transcription by RNA polymerase II);GO:0046546(development of primary male sexual characteristics);GO:0048018(receptor ligand activity);GO:0048546(digestive tract morphogenesis);GO:0050680(negative regulation of epithelial cell proliferation);GO:0050732(negative regulation of peptidyl-tyrosine phosphorylation);GO:0051216(cartilage development);GO:0060028(convergent extension involved in axis elongation);GO:0060349(bone morphogenesis);GO:0061056(sclerotome development);GO:0061133(endopeptidase activator activity);GO:0061185(negative regulation of dermatome development);GO:0071425(hematopoietic stem cell proliferation);GO:0071481(cellular response to X-ray);GO:0090090(negative regulation of canonical Wnt signaling pathway);GO:0090175(regulation of establishment of planar polarity);GO:0090179(planar cell polarity pathway involved in neural tube closure);GO:0090244(Wnt signaling pathway involved in somitogenesis);GO:0090263(positive regulation of canonical Wnt signaling pathway);GO:1902042(negative regulation of extrinsic apoptotic signaling pathway via death domain receptors);GO:1904956(regulation of midbrain dopaminergic neuron differentiation);GO:2000035(regulation of stem cell division);GO:2000041(negative regulation of planar cell polarity pathway involved in axis elongation);GO:2000041(negative regulation of planar cell polarity pathway involved in axis elongation)","04310(Wnt signaling pathway);04310(Wnt signaling pathway)","K02176","NA","secreted frizzled related protein 2 [Source:HGNC Symbol;Acc:HGNC:10777]","NA",{"v":55.2152503466667,"d":"55.22"},{"v":45.7891995377778,"d":"45.79"},{"v":53.0895897822222,"d":"53.09"},{"v":56.1842665333333,"d":"56.18"},{"v":58.2999445111111,"d":"58.30"},{"v":74.18444912,"d":"74.18"},{"v":52.0856660088889,"d":"52.09"},{"v":40.6071963955556,"d":"40.61"},{"v":78.6664965466667,"d":"78.67"},{"v":134.72294052,"d":"134.72"},{"v":52.5358056488889,"d":"52.54"},{"v":83.3335700133333,"d":"83.33"},{"v":84.1282598311111,"d":"84.13"},{"v":120.1461308,"d":"120.15"},{"v":102.235014871111,"d":"102.24"},{"v":83.0491592133333,"d":"83.05"},{"v":0.589395398009977,"d":"0.59"},{"v":-0.762692298921724,"d":"-0.76"},{"v":2.86057888656512e-15,"d":"0.00"},{"v":3.81471798818935e-14,"d":"0.00"},"down","no"]
["ENSAPLG00000004747","MFSD4A","ENSAPLT00000017170;ENSAPLT00000004894","NA","NA","NA","NA","major facilitator superfamily domain containing 4A [Source:HGNC Symbol;Acc:HGNC:25433]","NA",{"v":12.2400679259259,"d":"12.24"},{"v":9.69895833744856,"d":"9.70"},{"v":13.1862103550852,"d":"13.19"},{"v":11.4343572621987,"d":"11.43"},{"v":15.4908184444444,"d":"15.49"},{"v":13.9689584879483,"d":"13.97"},{"v":11.9097954320988,"d":"11.91"},{"v":13.5592169053498,"d":"13.56"},{"v":12.4413809588477,"d":"12.44"},{"v":37.2209261557907,"d":"37.22"},{"v":18.6212904609053,"d":"18.62"},{"v":31.5042728424456,"d":"31.50"},{"v":20.5085597283951,"d":"20.51"},{"v":32.0228220452675,"d":"32.02"},{"v":24.5264334767784,"d":"24.53"},{"v":22.0443441234568,"d":"22.04"},{"v":0.510273859663525,"d":"0.51"},{"v":-0.970656357730366,"d":"-0.97"},{"v":2.94562213064139e-15,"d":"0.00"},{"v":3.92308467335102e-14,"d":"0.00"},"down","no"]
["ENSAPLG00000005043","DUSP23","ENSAPLT00000005197","GO:0004725(protein tyrosine phosphatase activity);GO:0005654(nucleoplasm);GO:0008138(protein tyrosine/serine/threonine phosphatase activity);GO:0016311(dephosphorylation);GO:0016791(phosphatase activity)","NA","NA","NA","dual specificity phosphatase 23 [Source:HGNC Symbol;Acc:HGNC:21480]","NA",{"v":3.131635,"d":"3.13"},{"v":5.310932,"d":"5.31"},{"v":5.312111,"d":"5.31"},{"v":2.688436,"d":"2.69"},{"v":3.466231,"d":"3.47"},{"v":3.913657,"d":"3.91"},{"v":5.478771,"d":"5.48"},{"v":4.708639,"d":"4.71"},{"v":7.9542,"d":"7.95"},{"v":12.067486,"d":"12.07"},{"v":9.859114,"d":"9.86"},{"v":12.823818,"d":"12.82"},{"v":13.655955,"d":"13.66"},{"v":14.050944,"d":"14.05"},{"v":15.6265,"d":"15.63"},{"v":11.184269,"d":"11.18"},{"v":0.349821151088754,"d":"0.35"},{"v":-1.51531057392871,"d":"-1.52"},{"v":3.0360339578175e-15,"d":"0.00"},{"v":4.03831439902008e-14,"d":"0.00"},"down","yes"]
["ENSAPLG00000002417","DEPDC1","ENSAPLT00000002470;ENSAPLT00000020308","GO:0005634(nucleus);GO:0007165(signal transduction);GO:0017053(transcriptional repressor complex);GO:0035556(intracellular signal transduction);GO:0045892(negative regulation of transcription, DNA-templated);GO:0045892(negative regulation of transcription, DNA-templated)","NA","NA","NA","DEP domain containing 1 [Source:HGNC Symbol;Acc:HGNC:22949]","NA",{"v":3.996834,"d":"4.00"},{"v":5.213472799508,"d":"5.21"},{"v":4.71356753259533,"d":"4.71"},{"v":10.432473698647,"d":"10.43"},{"v":4.174598,"d":"4.17"},{"v":3.66264772324723,"d":"3.66"},{"v":4.6629380295203,"d":"4.66"},{"v":2.983114,"d":"2.98"},{"v":0.433806,"d":"0.43"},{"v":0.036351,"d":"0.04"},{"v":0.283853,"d":"0.28"},{"v":0.559482574415744,"d":"0.56"},{"v":0.701178,"d":"0.70"},{"v":0.252768,"d":"0.25"},{"v":0.352717,"d":"0.35"},{"v":0.0001,"d":"0.00"},{"v":15.2044885134539,"d":"15.20"},{"v":3.92642537909459,"d":"3.93"},{"v":3.04415998158989e-15,"d":"0.00"},{"v":4.04393851587645e-14,"d":"0.00"},"up","yes"]
["ENSAPLG00000010331","DCX","ENSAPLT00000010765","GO:0001764(neuron migration);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0007420(brain development);GO:0021766(hippocampus development);GO:0021819(layer formation in cerebral cortex);GO:0021860(pyramidal neuron development);GO:0021952(central nervous system projection neuron axonogenesis);GO:0035556(intracellular signal transduction);GO:0043005(neuron projection);GO:0048675(axon extension);GO:0048813(dendrite morphogenesis)","NA","NA","NA","doublecortin [Source:HGNC Symbol;Acc:HGNC:2714]","NA",{"v":2.814356,"d":"2.81"},{"v":3.69084,"d":"3.69"},{"v":3.801649,"d":"3.80"},{"v":5.349796,"d":"5.35"},{"v":2.558682,"d":"2.56"},{"v":4.441126,"d":"4.44"},{"v":2.201142,"d":"2.20"},{"v":3.728605,"d":"3.73"},{"v":0.096566,"d":"0.10"},{"v":0.30789,"d":"0.31"},{"v":0.0001,"d":"0.00"},{"v":0.298548,"d":"0.30"},{"v":0.246338,"d":"0.25"},{"v":0.345448,"d":"0.35"},{"v":0.521295,"d":"0.52"},{"v":0.436658,"d":"0.44"},{"v":12.688942815811,"d":"12.69"},{"v":3.66549997037677,"d":"3.67"},{"v":3.05389618838584e-15,"d":"0.00"},{"v":4.0516845210362e-14,"d":"0.00"},"up","yes"]
["ENSAPLG00000016313","BHLHE40","ENSAPLT00000017021","GO:0000122(negative regulation of transcription by RNA polymerase II);GO:0000978(RNA polymerase II proximal promoter sequence-specific DNA binding);GO:0000980(RNA polymerase II distal enhancer sequence-specific DNA binding);GO:0000981(DNA-binding transcription factor activity, RNA polymerase II-specific);GO:0001102(RNA polymerase II activating transcription factor binding);GO:0001227(DNA-binding transcription repressor activity, RNA polymerase II-specific);GO:0003677(DNA binding);GO:0003714(transcription corepressor activity);GO:0005634(nucleus);GO:0006355(regulation of transcription, DNA-templated);GO:0007623(circadian rhythm);GO:0009416(response to light stimulus);GO:0016604(nuclear body);GO:0019904(protein domain specific binding);GO:0032922(circadian regulation of gene expression);GO:0042752(regulation of circadian rhythm);GO:0042803(protein homodimerization activity);GO:0043153(entrainment of circadian clock by photoperiod);GO:0043425(bHLH transcription factor binding);GO:0043426(MRF binding);GO:0043433(negative regulation of DNA-binding transcription factor activity);GO:0045892(negative regulation of transcription, DNA-templated);GO:0046982(protein heterodimerization activity);GO:0046983(protein dimerization activity);GO:0070888(E-box binding)","NA","NA","NA","basic helix-loop-helix family member e40 [Source:HGNC Symbol;Acc:HGNC:1046]","NA",{"v":27.89151,"d":"27.89"},{"v":22.389128,"d":"22.39"},{"v":19.047644,"d":"19.05"},{"v":23.019739,"d":"23.02"},{"v":30.585623,"d":"30.59"},{"v":29.195194,"d":"29.20"},{"v":22.157452,"d":"22.16"},{"v":28.772835,"d":"28.77"},{"v":35.18716,"d":"35.19"},{"v":33.318665,"d":"33.32"},{"v":50.384102,"d":"50.38"},{"v":43.618885,"d":"43.62"},{"v":34.647713,"d":"34.65"},{"v":54.672169,"d":"54.67"},{"v":40.936245,"d":"40.94"},{"v":43.57077,"d":"43.57"},{"v":0.603739417392638,"d":"0.60"},{"v":-0.728002098904114,"d":"-0.73"},{"v":3.11313167733686e-15,"d":"0.00"},{"v":4.12499887003447e-14,"d":"0.00"},"down","no"]
["ENSAPLG00000028301","JUN","ENSAPLT00000023785","GO:0000980(RNA polymerase II distal enhancer sequence-specific DNA binding);GO:0000981(DNA-binding transcription factor activity, RNA polymerase II-specific);GO:0001102(RNA polymerase II activating transcription factor binding);GO:0001228(DNA-binding transcription activator activity, RNA polymerase II-specific);GO:0001525(angiogenesis);GO:0001774(microglial cell activation);GO:0001889(liver development);GO:0001938(positive regulation of endothelial cell proliferation);GO:0003151(outflow tract morphogenesis);GO:0003677(DNA binding);GO:0003682(chromatin binding);GO:0003700(DNA-binding transcription factor activity);GO:0003713(transcription coactivator activity);GO:0005096(GTPase activator activity);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005667(transcription factor complex);GO:0005719(nuclear euchromatin);GO:0006355(regulation of transcription, DNA-templated);GO:0007179(transforming growth factor beta receptor signaling pathway);GO:0007265(Ras protein signal transduction);GO:0008134(transcription factor binding);GO:0008285(negative regulation of cell population proliferation);GO:0009987(cellular process);GO:0010634(positive regulation of epithelial cell migration);GO:0017053(transcriptional repressor complex);GO:0019899(enzyme binding);GO:0030224(monocyte differentiation);GO:0031103(axon regeneration);GO:0031625(ubiquitin protein ligase binding);GO:0031953(negative regulation of protein autophosphorylation);GO:0034614(cellular response to reactive oxygen species);GO:0035026(leading edge cell differentiation);GO:0035497(cAMP response element binding);GO:0035976(transcription factor AP-1 complex);GO:0035994(response to muscle stretch);GO:0042493(response to drug);GO:0042802(identical protein binding);GO:0042803(protein homodimerization activity);GO:0043065(positive regulation of apoptotic process);GO:0043066(negative regulation of apoptotic process);GO:0043392(negative regulation of DNA binding);GO:0043524(negative regulation of neuron apoptotic process);GO:0043922(negative regulation by host of viral transcription);GO:0043923(positive regulation by host of viral transcription);GO:0044212(transcription regulatory region DNA binding);GO:0044389(ubiquitin-like protein ligase binding);GO:0045892(negative regulation of transcription, DNA-templated);GO:0045893(positive regulation of transcription, DNA-templated);GO:0045944(positive regulation of transcription by RNA polymerase II);GO:0046982(protein heterodimerization activity);GO:0048146(positive regulation of fibroblast proliferation);GO:0051726(regulation of cell cycle);GO:0060395(SMAD protein signal transduction);GO:0061029(eyelid development in camera-type eye);GO:0070374(positive regulation of ERK1 and ERK2 cascade);GO:0070412(R-SMAD binding);GO:0071276(cellular response to cadmium ion);GO:0071277(cellular response to calcium ion);GO:1902895(positive regulation of pri-miRNA transcription by RNA polymerase II);GO:1904707(positive regulation of vascular smooth muscle cell proliferation);GO:1990441(negative regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress);GO:2000144(positive regulation of DNA-templated transcription, initiation)","04010(MAPK signaling pathway);04012(ErbB signaling pathway);04310(Wnt signaling pathway);04137(Mitophagy - animal);04210(Apoptosis);04510(Focal adhesion);04530(Tight junction);04620(Toll-like receptor signaling pathway);04621(NOD-like receptor signaling pathway);04625(C-type lectin receptor signaling pathway);04912(GnRH signaling pathway);04933(AGE-RAGE signaling pathway in diabetic complications);05132(Salmonella infection);05164(Influenza A);05168(Herpes simplex infection)","K04448","NA","Jun proto-oncogene, AP-1 transcription factor subunit [Source:HGNC Symbol;Acc:HGNC:6204]","NA",{"v":81.124359,"d":"81.12"},{"v":92.764084,"d":"92.76"},{"v":182.067139,"d":"182.07"},{"v":98.693581,"d":"98.69"},{"v":92.917976,"d":"92.92"},{"v":73.298447,"d":"73.30"},{"v":73.045723,"d":"73.05"},{"v":75.30439,"d":"75.30"},{"v":123.791992,"d":"123.79"},{"v":203.085159,"d":"203.09"},{"v":144.413193,"d":"144.41"},{"v":147.691803,"d":"147.69"},{"v":224.99379,"d":"224.99"},{"v":168.366684,"d":"168.37"},{"v":183.123474,"d":"183.12"},{"v":198.424515,"d":"198.42"},{"v":0.551847966749701,"d":"0.55"},{"v":-0.857657233367736,"d":"-0.86"},{"v":3.13408230097418e-15,"d":"0.00"},{"v":4.14746222864887e-14,"d":"0.00"},"down","no"]
["ENSAPLG00000011392","GHITM","ENSAPLT00000011919","GO:0005739(mitochondrion)","NA","NA","NA","growth hormone inducible transmembrane protein [Source:HGNC Symbol;Acc:HGNC:17281]","NA",{"v":100.95034,"d":"100.95"},{"v":96.215965,"d":"96.22"},{"v":98.671722,"d":"98.67"},{"v":75.329491,"d":"75.33"},{"v":122.929482,"d":"122.93"},{"v":97.375473,"d":"97.38"},{"v":108.618073,"d":"108.62"},{"v":89.101578,"d":"89.10"},{"v":133.965836,"d":"133.97"},{"v":151.485855,"d":"151.49"},{"v":118.998894,"d":"119.00"},{"v":113.780136,"d":"113.78"},{"v":152.778839,"d":"152.78"},{"v":135.761032,"d":"135.76"},{"v":131.706635,"d":"131.71"},{"v":136.654373,"d":"136.65"},{"v":0.734042347932104,"d":"0.73"},{"v":-0.446064798318503,"d":"-0.45"},{"v":3.14021921251917e-15,"d":"0.00"},{"v":4.1502897235524e-14,"d":"0.00"},"down","no"]
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["ENSAPLG00000001269","DCBLD1","ENSAPLT00000001345","NA","NA","NA","NA","discoidin, CUB and LCCL domain containing 1 [Source:HGNC Symbol;Acc:HGNC:21479]","NA",{"v":21.760902,"d":"21.76"},{"v":14.77025,"d":"14.77"},{"v":20.358223,"d":"20.36"},{"v":22.960514,"d":"22.96"},{"v":19.438274,"d":"19.44"},{"v":20.033827,"d":"20.03"},{"v":18.433489,"d":"18.43"},{"v":20.080051,"d":"20.08"},{"v":6.974947,"d":"6.97"},{"v":7.285422,"d":"7.29"},{"v":5.923116,"d":"5.92"},{"v":7.324806,"d":"7.32"},{"v":5.771096,"d":"5.77"},{"v":6.446408,"d":"6.45"},{"v":5.491711,"d":"5.49"},{"v":7.9513,"d":"7.95"},{"v":2.96857390402937,"d":"2.97"},{"v":1.56977003011836,"d":"1.57"},{"v":2.1710680822689e-14,"d":"0.00"},{"v":2.60402674607397e-13,"d":"0.00"},"up","yes"]
["ENSAPLG00000009404","WWTR1","ENSAPLT00000035730;ENSAPLT00000017293;ENSAPLT00000048197;ENSAPLT00000009789","GO:0000122(negative regulation of transcription by RNA polymerase II);GO:0001649(osteoblast differentiation);GO:0001894(tissue homeostasis);GO:0001933(negative regulation of protein phosphorylation);GO:0003015(heart process);GO:0003713(transcription coactivator activity);GO:0003714(transcription corepressor activity);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005667(transcription factor complex);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0006355(regulation of transcription, DNA-templated);GO:0006469(negative regulation of protein kinase activity);GO:0008284(positive regulation of cell population proliferation);GO:0010718(positive regulation of epithelial to mesenchymal transition);GO:0016567(protein ubiquitination);GO:0016604(nuclear body);GO:0017145(stem cell division);GO:0031146(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process);GO:0032835(glomerulus development);GO:0035264(multicellular organism growth);GO:0035329(hippo signaling);GO:0042803(protein homodimerization activity);GO:0045599(negative regulation of fat cell differentiation);GO:0045944(positive regulation of transcription by RNA polymerase II);GO:0048762(mesenchymal cell differentiation);GO:0060271(cilium assembly);GO:0060390(regulation of SMAD protein signal transduction);GO:0060828(regulation of canonical Wnt signaling pathway);GO:0060993(kidney morphogenesis);GO:0072307(regulation of metanephric nephron tubule epithelial cell differentiation);GO:0090090(negative regulation of canonical Wnt signaling pathway);GO:0090090(negative regulation of canonical Wnt signaling pathway)","04390(Hippo signaling pathway);04392(Hippo signaling pathway - multiple species);04392(Hippo signaling pathway - multiple species)","K16820","NA","WW domain containing transcription regulator 1 [Source:HGNC Symbol;Acc:HGNC:24042]","NA",{"v":37.3308745257235,"d":"37.33"},{"v":33.2963852009646,"d":"33.30"},{"v":49.6018101800643,"d":"49.60"},{"v":75.5047852524116,"d":"75.50"},{"v":62.7104224780279,"d":"62.71"},{"v":52.2006415434084,"d":"52.20"},{"v":64.3859471913183,"d":"64.39"},{"v":60.1076580836013,"d":"60.11"},{"v":17.1446263263666,"d":"17.14"},{"v":10.1389589726688,"d":"10.14"},{"v":16.6814045241158,"d":"16.68"},{"v":18.1184568167203,"d":"18.12"},{"v":15.6895106237942,"d":"15.69"},{"v":9.94019679581994,"d":"9.94"},{"v":11.920757437299,"d":"11.92"},{"v":5.21196480868167,"d":"5.21"},{"v":4.15026837286144,"d":"4.15"},{"v":2.05320462987588,"d":"2.05"},{"v":2.22085882252423e-14,"d":"0.00"},{"v":2.66067093345137e-13,"d":"0.00"},"up","yes"]
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["ENSAPLG00000008518","PTPRM","ENSAPLT00000029550;ENSAPLT00000038143;ENSAPLT00000033580;ENSAPLT00000009028;ENSAPLT00000020518;ENSAPLT00000044365;ENSAPLT00000045800","GO:0001937(negative regulation of endothelial cell proliferation);GO:0004725(protein tyrosine phosphatase activity);GO:0005001(transmembrane receptor protein tyrosine phosphatase activity);GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0005886(plasma membrane);GO:0005911(cell-cell junction);GO:0005913(cell-cell adherens junction);GO:0006470(protein dephosphorylation);GO:0007156(homophilic cell adhesion via plasma membrane adhesion molecules);GO:0007165(signal transduction);GO:0010596(negative regulation of endothelial cell migration);GO:0010842(retina layer formation);GO:0016020(membrane);GO:0016311(dephosphorylation);GO:0016525(negative regulation of angiogenesis);GO:0016791(phosphatase activity);GO:0030027(lamellipodium);GO:0031175(neuron projection development);GO:0031290(retinal ganglion cell axon guidance);GO:0042493(response to drug);GO:0042802(identical protein binding);GO:0045296(cadherin binding);GO:0048471(perinuclear region of cytoplasm);GO:0097755(positive regulation of blood vessel diameter);GO:0097755(positive regulation of blood vessel diameter)","04514(Cell adhesion molecules (CAMs));04520(Adherens junction);04520(Adherens junction)","K05693","EC:3.1.3.48","protein tyrosine phosphatase, receptor type M [Source:HGNC Symbol;Acc:HGNC:9675]","NA",{"v":26.6703298125417,"d":"26.67"},{"v":25.0273343775851,"d":"25.03"},{"v":32.2206695496998,"d":"32.22"},{"v":40.4039908165444,"d":"40.40"},{"v":39.8215745403602,"d":"39.82"},{"v":32.4509729452969,"d":"32.45"},{"v":30.3246885403602,"d":"30.32"},{"v":31.7742656711141,"d":"31.77"},{"v":36.528306406938,"d":"36.53"},{"v":40.816028868579,"d":"40.82"},{"v":45.245664418946,"d":"45.25"},{"v":49.4493707631755,"d":"49.45"},{"v":43.7482808599066,"d":"43.75"},{"v":42.6889747891928,"d":"42.69"},{"v":43.0469117444963,"d":"43.05"},{"v":34.7276899452969,"d":"34.73"},{"v":0.769346859931886,"d":"0.77"},{"v":-0.378293911159212,"d":"-0.38"},{"v":2.90763713388153e-14,"d":"0.00"},{"v":3.44369124018503e-13,"d":"0.00"},"down","no"]
["ENSAPLG00000010396","ST7","ENSAPLT00000024222;ENSAPLT00000010858;ENSAPLT00000039925;ENSAPLT00000035573;ENSAPLT00000028075;ENSAPLT00000034889","NA","NA","NA","NA","suppression of tumorigenicity 7 [Source:HGNC Symbol;Acc:HGNC:11351]","NA",{"v":19.6679081320755,"d":"19.67"},{"v":18.7229473940325,"d":"18.72"},{"v":17.2818810342255,"d":"17.28"},{"v":14.527576794208,"d":"14.53"},{"v":14.7787569609478,"d":"14.78"},{"v":18.3355464971479,"d":"18.34"},{"v":21.5967793979816,"d":"21.60"},{"v":18.4476317112769,"d":"18.45"},{"v":34.2489848240456,"d":"34.25"},{"v":25.4221891790259,"d":"25.42"},{"v":34.1126649464677,"d":"34.11"},{"v":31.5720089039052,"d":"31.57"},{"v":21.5601319640193,"d":"21.56"},{"v":28.9447825353225,"d":"28.94"},{"v":22.6707344480035,"d":"22.67"},{"v":27.7309768433523,"d":"27.73"},{"v":0.633596131134701,"d":"0.63"},{"v":-0.658364568828775,"d":"-0.66"},{"v":3.00905036051875e-14,"d":"0.00"},{"v":3.55973745614391e-13,"d":"0.00"},"down","no"]
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["ENSAPLG00000002229","MYADML2","ENSAPLT00000002226","GO:0005737(cytoplasm);GO:0016020(membrane)","00330(Arginine and proline metabolism)","K00286","EC:1.5.1.2","myeloid associated differentiation marker like 2 [Source:HGNC Symbol;Acc:HGNC:34548]","NA",{"v":79.298859,"d":"79.30"},{"v":64.940399,"d":"64.94"},{"v":76.383263,"d":"76.38"},{"v":82.076385,"d":"82.08"},{"v":87.351036,"d":"87.35"},{"v":78.919662,"d":"78.92"},{"v":96.283356,"d":"96.28"},{"v":88.097733,"d":"88.10"},{"v":32.760178,"d":"32.76"},{"v":37.407696,"d":"37.41"},{"v":26.638569,"d":"26.64"},{"v":19.072836,"d":"19.07"},{"v":30.140404,"d":"30.14"},{"v":22.718111,"d":"22.72"},{"v":27.175806,"d":"27.18"},{"v":34.830578,"d":"34.83"},{"v":2.83149372895554,"d":"2.83"},{"v":1.50156333462339,"d":"1.50"},{"v":3.545771040929e-14,"d":"0.00"},{"v":4.16618058319801e-13,"d":"0.00"},"up","yes"]
["ENSAPLG00000006151","BRI3","ENSAPLT00000006367","GO:0042802(identical protein binding)","NA","NA","NA","brain protein I3 [Source:HGNC Symbol;Acc:HGNC:1109]","NA",{"v":56.594269,"d":"56.59"},{"v":91.832169,"d":"91.83"},{"v":59.622189,"d":"59.62"},{"v":52.228218,"d":"52.23"},{"v":88.925423,"d":"88.93"},{"v":66.881203,"d":"66.88"},{"v":60.819897,"d":"60.82"},{"v":88.012367,"d":"88.01"},{"v":99.851387,"d":"99.85"},{"v":105.089874,"d":"105.09"},{"v":141.823212,"d":"141.82"},{"v":107.126877,"d":"107.13"},{"v":103.105682,"d":"103.11"},{"v":132.827133,"d":"132.83"},{"v":136.886536,"d":"136.89"},{"v":123.438751,"d":"123.44"},{"v":0.594554608026022,"d":"0.59"},{"v":-0.75011877169482,"d":"-0.75"},{"v":3.55308774786457e-14,"d":"0.00"},{"v":4.17005490770304e-13,"d":"0.00"},"down","no"]
["ENSAPLG00000028961","ENSAPLG00000028961","ENSAPLT00000018352","NA","NA","NA","NA",null,"NA",{"v":367.469574,"d":"367.47"},{"v":292.27298,"d":"292.27"},{"v":381.364441,"d":"381.36"},{"v":321.855347,"d":"321.86"},{"v":359.926239,"d":"359.93"},{"v":388.467133,"d":"388.47"},{"v":328.632935,"d":"328.63"},{"v":310.92981,"d":"310.93"},{"v":408.981018,"d":"408.98"},{"v":414.805145,"d":"414.81"},{"v":421.916718,"d":"421.92"},{"v":400.766632,"d":"400.77"},{"v":435.112274,"d":"435.11"},{"v":497.450867,"d":"497.45"},{"v":448.731354,"d":"448.73"},{"v":479.245789,"d":"479.25"},{"v":0.784405695516795,"d":"0.78"},{"v":-0.350328084007983,"d":"-0.35"},{"v":3.61888322597051e-14,"d":"0.00"},{"v":4.24247609824226e-13,"d":"0.00"},"down","no"]
["ENSAPLG00000001340","NOC4L","ENSAPLT00000001526","GO:0005634(nucleus);GO:0005730(nucleolus);GO:0042254(ribosome biogenesis)","NA","NA","NA","nucleolar complex associated 4 homolog [Source:HGNC Symbol;Acc:HGNC:28461]","NA",{"v":22.840054,"d":"22.84"},{"v":30.51827,"d":"30.52"},{"v":27.42326,"d":"27.42"},{"v":23.121872,"d":"23.12"},{"v":24.413237,"d":"24.41"},{"v":16.562729,"d":"16.56"},{"v":25.931868,"d":"25.93"},{"v":23.687178,"d":"23.69"},{"v":7.231018,"d":"7.23"},{"v":7.256869,"d":"7.26"},{"v":6.924261,"d":"6.92"},{"v":10.911638,"d":"10.91"},{"v":6.436183,"d":"6.44"},{"v":6.392859,"d":"6.39"},{"v":4.976002,"d":"4.98"},{"v":5.464743,"d":"5.46"},{"v":3.49857829789066,"d":"3.50"},{"v":1.80676877940872,"d":"1.81"},{"v":3.97008128910111e-14,"d":"0.00"},{"v":4.64893830411106e-13,"d":"0.00"},"up","yes"]
["ENSAPLG00000022802","SH3BGRL","ENSAPLT00000023744","NA","NA","NA","NA","SH3 domain binding glutamate rich protein like [Source:HGNC Symbol;Acc:HGNC:10823]","NA",{"v":70.900253,"d":"70.90"},{"v":62.299973,"d":"62.30"},{"v":77.457336,"d":"77.46"},{"v":59.705383,"d":"59.71"},{"v":77.172935,"d":"77.17"},{"v":73.562775,"d":"73.56"},{"v":67.328362,"d":"67.33"},{"v":70.34362,"d":"70.34"},{"v":23.393938,"d":"23.39"},{"v":23.819946,"d":"23.82"},{"v":13.541741,"d":"13.54"},{"v":24.274759,"d":"24.27"},{"v":21.290684,"d":"21.29"},{"v":23.290157,"d":"23.29"},{"v":29.919144,"d":"29.92"},{"v":23.625832,"d":"23.63"},{"v":3.05078743689382,"d":"3.05"},{"v":1.60918166388173,"d":"1.61"},{"v":4.20900611108128e-14,"d":"0.00"},{"v":4.91961987118731e-13,"d":"0.00"},"up","yes"]
["ENSAPLG00000006111","SFRP1","ENSAPLT00000006335","GO:0001649(osteoblast differentiation);GO:0001657(ureteric bud development);GO:0001756(somitogenesis);GO:0001843(neural tube closure);GO:0002244(hematopoietic progenitor cell differentiation);GO:0004197(cysteine-type endopeptidase activity);GO:0005109(frizzled binding);GO:0005515(protein binding);GO:0005615(extracellular space);GO:0005829(cytosol);GO:0008144(drug binding);GO:0008201(heparin binding);GO:0008284(positive regulation of cell population proliferation);GO:0008285(negative regulation of cell population proliferation);GO:0008584(male gonad development);GO:0008585(female gonad development);GO:0009267(cellular response to starvation);GO:0009950(dorsal/ventral axis specification);GO:0009952(anterior/posterior pattern specification);GO:0009986(cell surface);GO:0010564(regulation of cell cycle process);GO:0010629(negative regulation of gene expression);GO:0010719(negative regulation of epithelial to mesenchymal transition);GO:0010975(regulation of neuron projection development);GO:0014034(neural crest cell fate commitment);GO:0014070(response to organic cyclic compound);GO:0017147(Wnt-protein binding);GO:0021915(neural tube development);GO:0030097(hemopoiesis);GO:0030177(positive regulation of Wnt signaling pathway);GO:0030178(negative regulation of Wnt signaling pathway);GO:0030279(negative regulation of ossification);GO:0030307(positive regulation of cell growth);GO:0030308(negative regulation of cell growth);GO:0030336(negative regulation of cell migration);GO:0030514(negative regulation of BMP signaling pathway);GO:0033689(negative regulation of osteoblast proliferation);GO:0035019(somatic stem cell population maintenance);GO:0042493(response to drug);GO:0042802(identical protein binding);GO:0043065(positive regulation of apoptotic process);GO:0043066(negative regulation of apoptotic process);GO:0043508(negative regulation of JUN kinase activity);GO:0044344(cellular response to fibroblast growth factor stimulus);GO:0044345(stromal-epithelial cell signaling involved in prostate gland development);GO:0045578(negative regulation of B cell differentiation);GO:0045600(positive regulation of fat cell differentiation);GO:0045668(negative regulation of osteoblast differentiation);GO:0045671(negative regulation of osteoclast differentiation);GO:0045880(positive regulation of smoothened signaling pathway);GO:0045892(negative regulation of transcription, DNA-templated);GO:0045893(positive regulation of transcription, DNA-templated);GO:0046546(development of primary male sexual characteristics);GO:0046676(negative regulation of insulin secretion);GO:0046851(negative regulation of bone remodeling);GO:0048147(negative regulation of fibroblast proliferation);GO:0048546(digestive tract morphogenesis);GO:0050679(positive regulation of epithelial cell proliferation);GO:0050680(negative regulation of epithelial cell proliferation);GO:0050732(negative regulation of peptidyl-tyrosine phosphorylation);GO:0060070(canonical Wnt signaling pathway);GO:0060071(Wnt signaling pathway, planar cell polarity pathway);GO:0060218(hematopoietic stem cell differentiation);GO:0060346(bone trabecula formation);GO:0060527(prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis);GO:0060687(regulation of branching involved in prostate gland morphogenesis);GO:0060766(negative regulation of androgen receptor signaling pathway);GO:0062023(collagen-containing extracellular matrix);GO:0071305(cellular response to vitamin D);GO:0071347(cellular response to interleukin-1);GO:0071356(cellular response to tumor necrosis factor);GO:0071363(cellular response to growth factor stimulus);GO:0071380(cellular response to prostaglandin E stimulus);GO:0071391(cellular response to estrogen stimulus);GO:0071392(cellular response to estradiol stimulus);GO:0071456(cellular response to hypoxia);GO:0071481(cellular response to X-ray);GO:0071504(cellular response to 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specification);GO:2000080(negative regulation of canonical Wnt signaling pathway involved in controlling type B pancreatic cell proliferation);GO:2000270(negative regulation of fibroblast apoptotic process);GO:2000271(positive regulation of fibroblast apoptotic process);GO:2001238(positive regulation of extrinsic apoptotic signaling pathway)","04310(Wnt signaling pathway)","K02166","NA","secreted frizzled related protein 1 [Source:HGNC 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["ENSAPLG00000013903","TMEM30A","ENSAPLT00000014516","GO:0005783(endoplasmic reticulum);GO:0005886(plasma membrane);GO:0006855(drug transmembrane transport);GO:0010976(positive regulation of neuron projection development);GO:0015247(aminophospholipid transmembrane transporter activity);GO:0015914(phospholipid transport);GO:0015917(aminophospholipid transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0036010(protein localization to endosome);GO:0045332(phospholipid translocation);GO:0070863(positive regulation of protein exit from endoplasmic reticulum)","NA","NA","NA","transmembrane protein 30A [Source:HGNC Symbol;Acc:HGNC:16667]","NA",{"v":37.574615,"d":"37.57"},{"v":36.399853,"d":"36.40"},{"v":39.748974,"d":"39.75"},{"v":40.886814,"d":"40.89"},{"v":45.369823,"d":"45.37"},{"v":39.572216,"d":"39.57"},{"v":32.228371,"d":"32.23"},{"v":36.447319,"d":"36.45"},{"v":45.769669,"d":"45.77"},{"v":47.78347,"d":"47.78"},{"v":39.649246,"d":"39.65"},{"v":41.197792,"d":"41.20"},{"v":50.6339,"d":"50.63"},{"v":44.786205,"d":"44.79"},{"v":62.091785,"d":"62.09"},{"v":54.128262,"d":"54.13"},{"v":0.798434675979151,"d":"0.80"},{"v":-0.324753716676102,"d":"-0.32"},{"v":3.06473515623636e-13,"d":"0.00"},{"v":3.31214867145336e-12,"d":"0.00"},"down","no"]
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["ENSAPLG00000031009","EDN1","ENSAPLT00000023282","GO:0000122(negative regulation of transcription by RNA polymerase II);GO:0001501(skeletal system development);GO:0001516(prostaglandin biosynthetic process);GO:0001569(branching involved in blood vessel morphogenesis);GO:0001666(response to hypoxia);GO:0001701(in utero embryonic development);GO:0003100(regulation of systemic arterial blood pressure by endothelin);GO:0005102(signaling receptor binding);GO:0005125(cytokine activity);GO:0005179(hormone activity);GO:0005576(extracellular region);GO:0005615(extracellular space);GO:0005737(cytoplasm);GO:0006885(regulation of pH);GO:0007166(cell surface receptor signaling pathway);GO:0007186(G protein-coupled receptor signaling pathway);GO:0007193(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway);GO:0007204(positive regulation of cytosolic calcium ion concentration);GO:0007205(protein kinase C-activating G protein-coupled receptor signaling pathway);GO:0007267(cell-cell signaling);GO:0007507(heart development);GO:0007585(respiratory gaseous exchange);GO:0007589(body fluid secretion);GO:0008217(regulation of blood pressure);GO:0008284(positive regulation of cell population proliferation);GO:0009953(dorsal/ventral pattern formation);GO:0010460(positive regulation of heart rate);GO:0010613(positive regulation of cardiac muscle hypertrophy);GO:0010827(regulation of glucose transmembrane transport);GO:0010870(positive regulation of receptor biosynthetic process);GO:0014032(neural crest cell development);GO:0014065(phosphatidylinositol 3-kinase signaling);GO:0014824(artery smooth muscle contraction);GO:0014826(vein smooth muscle contraction);GO:0019229(regulation of vasoconstriction);GO:0019722(calcium-mediated signaling);GO:0030072(peptide hormone secretion);GO:0030185(nitric oxide transport);GO:0030335(positive regulation of cell migration);GO:0031583(phospholipase D-activating G protein-coupled receptor signaling pathway);GO:0031707(endothelin A receptor binding);GO:0031708(endothelin B receptor binding);GO:0032269(negative regulation of cellular protein metabolic process);GO:0035810(positive regulation of urine volume);GO:0035815(positive regulation of renal sodium excretion);GO:0042310(vasoconstriction);GO:0042313(protein kinase C deactivation);GO:0042474(middle ear morphogenesis);GO:0043179(rhythmic excitation);GO:0043406(positive regulation of MAP kinase activity);GO:0043507(positive regulation of JUN kinase activity);GO:0045793(positive regulation of cell size);GO:0045840(positive regulation of mitotic nuclear division);GO:0045944(positive regulation of transcription by RNA polymerase II);GO:0045987(positive regulation of smooth muscle contraction);GO:0046887(positive regulation of hormone secretion);GO:0048016(inositol phosphate-mediated signaling);GO:0048514(blood vessel morphogenesis);GO:0048661(positive regulation of smooth muscle cell proliferation);GO:0051091(positive regulation of DNA-binding transcription factor activity);GO:0051216(cartilage development);GO:0051482(positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway);GO:0051771(negative regulation of nitric-oxide synthase biosynthetic process);GO:0060298(positive regulation of sarcomere organization);GO:0060585(positive regulation of prostaglandin-endoperoxide synthase activity);GO:0061051(positive regulation of cell growth involved in cardiac muscle cell development)","04916(Melanogenesis);04270(Vascular smooth muscle contraction);04933(AGE-RAGE signaling pathway in diabetic complications)","K16366","NA","endothelin 1 [Source:HGNC Symbol;Acc:HGNC:3176]","NA",{"v":1.773956,"d":"1.77"},{"v":2.502507,"d":"2.50"},{"v":2.421482,"d":"2.42"},{"v":2.443816,"d":"2.44"},{"v":1.809543,"d":"1.81"},{"v":2.022024,"d":"2.02"},{"v":2.932452,"d":"2.93"},{"v":0.740732,"d":"0.74"},{"v":5.479897,"d":"5.48"},{"v":3.646119,"d":"3.65"},{"v":4.652798,"d":"4.65"},7.72,{"v":4.316686,"d":"4.32"},{"v":6.353886,"d":"6.35"},{"v":3.774908,"d":"3.77"},{"v":5.714056,"d":"5.71"},{"v":0.399596047371055,"d":"0.40"},{"v":-1.32338578219342,"d":"-1.32"},{"v":3.15044628693716e-13,"d":"0.00"},{"v":3.39770064729449e-12,"d":"0.00"},"down","yes"]
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["ENSAPLG00000030755","ENSAPLG00000030755","ENSAPLT00000025511","GO:0005515(protein binding)","NA","NA","NA",null,"NA",{"v":2.74607,"d":"2.75"},{"v":3.607394,"d":"3.61"},{"v":2.786452,"d":"2.79"},{"v":1.94718,"d":"1.95"},{"v":1.946999,"d":"1.95"},{"v":2.0873,"d":"2.09"},{"v":0.701045,"d":"0.70"},{"v":2.521421,"d":"2.52"},{"v":0.0001,"d":"0.00"},{"v":0.0001,"d":"0.00"},{"v":0.0001,"d":"0.00"},{"v":0.0001,"d":"0.00"},{"v":0.086655,"d":"0.09"},{"v":0.0001,"d":"0.00"},{"v":0.291206,"d":"0.29"},{"v":0.093105,"d":"0.09"},{"v":38.9081312332172,"d":"38.91"},{"v":5.28199978387674,"d":"5.28"},{"v":3.19524268338034e-13,"d":"0.00"},{"v":3.4388633651526e-12,"d":"0.00"},"up","yes"]
["ENSAPLG00000005618","CHCHD3","ENSAPLT00000017919;ENSAPLT00000005804;ENSAPLT00000042299","GO:0005739(mitochondrion);GO:0005743(mitochondrial inner membrane);GO:0032947(protein-containing complex scaffold activity);GO:0061617(MICOS complex);GO:0061617(MICOS complex)","NA","NA","NA","coiled-coil-helix-coiled-coil-helix domain containing 3 [Source:HGNC Symbol;Acc:HGNC:21906]","NA",{"v":88.3418413837696,"d":"88.34"},{"v":90.4084014643979,"d":"90.41"},{"v":94.8070486743456,"d":"94.81"},{"v":85.8684057062827,"d":"85.87"},{"v":85.5093662874346,"d":"85.51"},{"v":96.598371339267,"d":"96.60"},{"v":89.1965440790576,"d":"89.20"},{"v":90.9033270549738,"d":"90.90"},{"v":107.541932825654,"d":"107.54"},{"v":107.712789777487,"d":"107.71"},{"v":112.289661204188,"d":"112.29"},{"v":88.6577320366492,"d":"88.66"},{"v":118.480245895288,"d":"118.48"},{"v":107.366477679581,"d":"107.37"},{"v":121.672390005236,"d":"121.67"},{"v":131.815831613089,"d":"131.82"},{"v":0.805810655288531,"d":"0.81"},{"v":-0.311487212421095,"d":"-0.31"},{"v":3.20692457776417e-13,"d":"0.00"},{"v":3.44785932583454e-12,"d":"0.00"},"down","no"]
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["ENSAPLG00000009855","KIF14","ENSAPLT00000028113;ENSAPLT00000010271;ENSAPLT00000036953","GO:0001558(regulation of cell growth);GO:0003777(microtubule motor activity);GO:0005515(protein binding);GO:0005524(ATP binding);GO:0005829(cytosol);GO:0005874(microtubule);GO:0005886(plasma membrane);GO:0007018(microtubule-based movement);GO:0007080(mitotic metaphase plate congression);GO:0008017(microtubule binding);GO:0008284(positive regulation of cell population proliferation);GO:0008574(ATP-dependent microtubule motor activity, plus-end-directed);GO:0010389(regulation of G2/M transition of mitotic cell cycle);GO:0015631(tubulin binding);GO:0016887(ATPase activity);GO:0019901(protein kinase binding);GO:0021685(cerebellar granular layer structural organization);GO:0021693(cerebellar Purkinje cell layer structural organization);GO:0021695(cerebellar cortex development);GO:0021766(hippocampus development);GO:0021772(olfactory bulb development);GO:0021846(cell proliferation in forebrain);GO:0021987(cerebral cortex development);GO:0030155(regulation of cell adhesion);GO:0030165(PDZ domain binding);GO:0030334(regulation of cell migration);GO:0030496(midbody);GO:0031146(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process);GO:0031641(regulation of myelination);GO:0032147(activation of protein kinase activity);GO:0032467(positive regulation of cytokinesis);GO:0032487(regulation of Rap protein signal transduction);GO:0033624(negative regulation of integrin activation);GO:0034446(substrate adhesion-dependent cell spreading);GO:0043066(negative regulation of apoptotic process);GO:0043161(proteasome-mediated ubiquitin-dependent protein catabolic process);GO:0043523(regulation of neuron apoptotic process);GO:0043524(negative regulation of neuron apoptotic process);GO:0045184(establishment of protein localization);GO:0051233(spindle midzone);GO:0051301(cell division);GO:0090543(Flemming body);GO:1903429(regulation of cell maturation);GO:2000045(regulation of G1/S transition of mitotic cell cycle);GO:2000045(regulation of G1/S transition of mitotic cell cycle)","NA","NA","NA","kinesin family member 14 [Source:HGNC Symbol;Acc:HGNC:19181]","NA",{"v":0.235851,"d":"0.24"},{"v":0.575319,"d":"0.58"},{"v":0.160988,"d":"0.16"},{"v":0.776734,"d":"0.78"},{"v":0.497555,"d":"0.50"},{"v":0.578853,"d":"0.58"},{"v":0.466762,"d":"0.47"},{"v":0.363766,"d":"0.36"},{"v":0.021319,"d":"0.02"},{"v":0.033161,"d":"0.03"},{"v":0.037524,"d":"0.04"},{"v":0.065143,"d":"0.07"},{"v":0.053486,"d":"0.05"},{"v":0.039033,"d":"0.04"},{"v":0.039336,"d":"0.04"},{"v":0.049836,"d":"0.05"},{"v":10.7893093454689,"d":"10.79"},{"v":3.43153061163567,"d":"3.43"},{"v":3.3547001586439e-13,"d":"0.00"},{"v":3.5992775745533e-12,"d":"0.00"},"up","yes"]
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["ENSAPLG00000008998","PRKCB","ENSAPLT00000036133;ENSAPLT00000009388","GO:0003682(chromatin binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0004697(protein kinase C activity);GO:0005080(protein kinase C binding);GO:0005246(calcium channel regulator activity);GO:0005524(ATP binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0006357(regulation of transcription by RNA polymerase II);GO:0006468(protein phosphorylation);GO:0006816(calcium ion transport);GO:0006874(cellular calcium ion homeostasis);GO:0008270(zinc ion binding);GO:0010829(negative regulation of glucose transmembrane transport);GO:0030374(nuclear receptor transcription coactivator activity);GO:0030949(positive regulation of vascular endothelial growth factor receptor signaling pathway);GO:0035403(histone kinase activity (H3-T6 specific));GO:0035408(histone H3-T6 phosphorylation);GO:0035556(intracellular signal transduction);GO:0042113(B cell activation);GO:0042393(histone binding);GO:0043123(positive regulation of I-kappaB kinase/NF-kappaB signaling);GO:0044305(calyx of Held);GO:0045766(positive regulation of angiogenesis);GO:0050681(androgen receptor binding);GO:0050853(B cell receptor signaling pathway);GO:0050861(positive regulation of B cell receptor signaling pathway);GO:0051092(positive regulation of NF-kappaB transcription factor activity);GO:0071322(cellular response to carbohydrate stimulus);GO:0099171(presynaptic modulation of chemical synaptic transmission);GO:0099523(presynaptic cytosol);GO:2000300(regulation of synaptic vesicle exocytosis);GO:2000300(regulation of synaptic vesicle exocytosis)","04014(Ras signaling pathway);04015(Rap1 signaling pathway);04010(MAPK signaling pathway);04012(ErbB signaling pathway);04310(Wnt signaling pathway);04370(VEGF signaling pathway);04064(NF-kappa B signaling pathway);04066(HIF-1 signaling pathway);04020(Calcium signaling pathway);04070(Phosphatidylinositol signaling system);04071(Sphingolipid signaling pathway);04150(mTOR signaling pathway);04510(Focal adhesion);04540(Gap junction);04650(Natural killer cell mediated cytotoxicity);04662(B cell receptor signaling pathway);04666(Fc gamma R-mediated phagocytosis);04670(Leukocyte transendothelial migration);04062(Chemokine signaling pathway);04911(Insulin secretion);04912(GnRH signaling pathway);04921(Oxytocin signaling pathway);04918(Thyroid hormone synthesis);04919(Thyroid hormone signaling pathway);04928(Parathyroid hormone synthesis, secretion and action);04916(Melanogenesis);04925(Aldosterone synthesis and secretion);04270(Vascular smooth muscle contraction);04970(Salivary secretion);04971(Gastric acid secretion);04972(Pancreatic secretion);04973(Carbohydrate digestion and absorption);04960(Aldosterone-regulated sodium reabsorption);04961(Endocrine and other factor-regulated calcium reabsorption);04724(Glutamatergic synapse);04727(GABAergic synapse);04725(Cholinergic synapse);04728(Dopaminergic synapse);04726(Serotonergic synapse);04720(Long-term potentiation);04730(Long-term depression);04723(Retrograde endocannabinoid signaling);04750(Inflammatory mediator regulation of TRP channels);04713(Circadian entrainment);05200(Pathways in cancer);05231(Choline metabolism in cancer);05206(MicroRNAs in cancer);05205(Proteoglycans in cancer);05225(Hepatocellular carcinoma);05214(Glioma);05223(Non-small cell lung cancer);05031(Amphetamine addiction);05032(Morphine addiction);04931(Insulin resistance);04933(AGE-RAGE signaling pathway in diabetic complications);05161(Hepatitis B);05163(Human cytomegalovirus infection);05146(Amoebiasis);05140(Leishmaniasis);05143(African trypanosomiasis);01521(EGFR tyrosine kinase inhibitor resistance);01521(EGFR tyrosine kinase inhibitor resistance)","K19662","EC:2.7.11.13","protein kinase C beta [Source:HGNC Symbol;Acc:HGNC:9395]","NA",{"v":5.40858623237653,"d":"5.41"},{"v":4.99880260953989,"d":"5.00"},{"v":5.57020472140144,"d":"5.57"},{"v":4.15140503060363,"d":"4.15"},{"v":6.5574220156184,"d":"6.56"},{"v":4.78955009202195,"d":"4.79"},{"v":5.16128672963276,"d":"5.16"},{"v":5.69110172140144,"d":"5.69"},{"v":1.92450144174757,"d":"1.92"},{"v":2.06063045799916,"d":"2.06"},{"v":1.60244046433094,"d":"1.60"},{"v":2.57327057513719,"d":"2.57"},{"v":1.90426296686366,"d":"1.90"},{"v":2.40144455888561,"d":"2.40"},{"v":1.24689602152807,"d":"1.25"},{"v":2.26529126086957,"d":"2.27"},{"v":2.64904273553052,"d":"2.65"},{"v":1.40547111809056,"d":"1.41"},{"v":3.30325767802911e-08,"d":"0.00"},{"v":1.91566788203197e-07,"d":"0.00"},"up","yes"]
["ENSAPLG00000002405","PLPP2","ENSAPLT00000002432","GO:0008195(phosphatidate phosphatase activity)","00561(Glycerolipid metabolism);00564(Glycerophospholipid metabolism);00565(Ether lipid metabolism);00600(Sphingolipid metabolism)","K01080","EC:3.1.3.4","phospholipid phosphatase 2 [Source:HGNC Symbol;Acc:HGNC:9230]","NA",{"v":17.621258,"d":"17.62"},{"v":18.47583,"d":"18.48"},{"v":16.829277,"d":"16.83"},{"v":15.366379,"d":"15.37"},{"v":16.6171,"d":"16.62"},{"v":21.371651,"d":"21.37"},{"v":16.300869,"d":"16.30"},{"v":17.622675,"d":"17.62"},{"v":17.904743,"d":"17.90"},{"v":19.94315,"d":"19.94"},{"v":19.743597,"d":"19.74"},{"v":25.099939,"d":"25.10"},{"v":20.179562,"d":"20.18"},{"v":25.691082,"d":"25.69"},{"v":18.973843,"d":"18.97"},{"v":18.394583,"d":"18.39"},{"v":0.844962438159124,"d":"0.84"},{"v":-0.243040885428664,"d":"-0.24"},{"v":4.28417003184953e-08,"d":"0.00"},{"v":2.45842168586498e-07,"d":"0.00"},"down","no"]
["ENSAPLG00000005511","COL6A3","ENSAPLT00000005838;ENSAPLT00000040566;ENSAPLT00000026823;ENSAPLT00000033606;ENSAPLT00000034921;ENSAPLT00000036619","GO:0004867(serine-type endopeptidase inhibitor activity);GO:0005515(protein binding);GO:0005581(collagen trimer);GO:0005615(extracellular space);GO:0031012(extracellular matrix);GO:0042383(sarcolemma);GO:0042383(sarcolemma)","04512(ECM-receptor interaction);04510(Focal adhesion);04510(Focal adhesion)","K06238","NA","collagen type VI alpha 3 chain [Source:HGNC Symbol;Acc:HGNC:2213]","NA",{"v":112.577601904067,"d":"112.58"},{"v":57.6765160514395,"d":"57.68"},{"v":127.465468647775,"d":"127.47"},{"v":87.0602067148178,"d":"87.06"},{"v":103.113404226696,"d":"103.11"},{"v":125.165147277733,"d":"125.17"},{"v":112.079924276928,"d":"112.08"},{"v":111.535359750352,"d":"111.54"},{"v":118.470875970405,"d":"118.47"},{"v":123.70113098178,"d":"123.70"},{"v":108.100379939098,"d":"108.10"},{"v":155.766281070566,"d":"155.77"},{"v":159.303501364908,"d":"159.30"},{"v":122.689670546507,"d":"122.69"},{"v":158.322018726696,"d":"158.32"},{"v":101.442752904067,"d":"101.44"},{"v":0.798507668056715,"d":"0.80"},{"v":-0.324621833006298,"d":"-0.32"},{"v":4.85618241759911e-08,"d":"0.00"},{"v":2.76981267633814e-07,"d":"0.00"},"down","no"]
["ENSAPLG00000016414","CELSR1","ENSAPLT00000017137","GO:0001736(establishment of planar polarity);GO:0001764(neuron migration);GO:0001843(neural tube closure);GO:0001942(hair follicle development);GO:0004888(transmembrane signaling receptor activity);GO:0004930(G protein-coupled receptor activity);GO:0005509(calcium ion binding);GO:0005654(nucleoplasm);GO:0005886(plasma membrane);GO:0007155(cell adhesion);GO:0007156(homophilic cell adhesion via plasma membrane adhesion molecules);GO:0007166(cell surface receptor signaling pathway);GO:0007186(G protein-coupled receptor signaling pathway);GO:0007266(Rho protein signal transduction);GO:0007626(locomotory behavior);GO:0009952(anterior/posterior pattern specification);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0032956(regulation of actin cytoskeleton organization);GO:0042060(wound healing);GO:0042249(establishment of planar polarity of embryonic epithelium);GO:0042472(inner ear morphogenesis);GO:0045176(apical protein localization);GO:0048105(establishment of body hair planar orientation);GO:0060488(orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis);GO:0060489(planar dichotomous subdivision of terminal units involved in lung branching morphogenesis);GO:0060490(lateral sprouting involved in lung morphogenesis);GO:0090179(planar cell polarity pathway involved in neural tube closure);GO:0090251(protein localization involved in establishment of planar polarity)","NA","NA","NA","cadherin EGF LAG seven-pass G-type receptor 1 [Source:HGNC Symbol;Acc:HGNC:1850]","NA",{"v":17.730642,"d":"17.73"},{"v":9.55678,"d":"9.56"},{"v":15.52031,"d":"15.52"},{"v":14.195693,"d":"14.20"},{"v":19.932173,"d":"19.93"},{"v":17.985075,"d":"17.99"},{"v":16.969,"d":"16.97"},{"v":15.569818,"d":"15.57"},{"v":7.230691,"d":"7.23"},{"v":7.428059,"d":"7.43"},{"v":2.784523,"d":"2.78"},{"v":5.011029,"d":"5.01"},{"v":6.004023,"d":"6.00"},{"v":7.400342,"d":"7.40"},{"v":5.938964,"d":"5.94"},{"v":7.323844,"d":"7.32"},{"v":2.59478142706423,"d":"2.59"},{"v":1.37561301743814,"d":"1.38"},{"v":5.43251540607861e-08,"d":"0.00"},{"v":3.07319233031982e-07,"d":"0.00"},"up","yes"]
["ENSAPLG00000010005","DYNC2LI1","ENSAPLT00000010442","GO:0005737(cytoplasm);GO:0005813(centrosome);GO:0005868(cytoplasmic dynein complex);GO:0005930(axoneme);GO:0007368(determination of left/right symmetry);GO:0008569(ATP-dependent microtubule motor activity, minus-end-directed);GO:0030990(intraciliary transport particle);GO:0031514(motile cilium);GO:0035721(intraciliary retrograde transport);GO:0035735(intraciliary transport involved in cilium assembly);GO:0035869(ciliary transition zone);GO:0036064(ciliary basal body);GO:0045177(apical part of cell);GO:0060271(cilium assembly);GO:1902017(regulation of cilium assembly)","NA","NA","NA","dynein cytoplasmic 2 light intermediate chain 1 [Source:HGNC Symbol;Acc:HGNC:24595]","NA",{"v":26.237423,"d":"26.24"},{"v":19.939493,"d":"19.94"},{"v":32.185844,"d":"32.19"},{"v":29.228983,"d":"29.23"},{"v":26.379942,"d":"26.38"},{"v":24.765659,"d":"24.77"},{"v":33.349884,"d":"33.35"},{"v":31.575233,"d":"31.58"},{"v":8.106785,"d":"8.11"},{"v":9.182699,"d":"9.18"},{"v":12.211493,"d":"12.21"},{"v":11.594914,"d":"11.59"},{"v":10.115522,"d":"10.12"},{"v":9.551211,"d":"9.55"},{"v":16.035444,"d":"16.04"},{"v":9.789001,"d":"9.79"},{"v":2.58309310596944,"d":"2.58"},{"v":1.36909964543019,"d":"1.37"},{"v":6.33008662559119e-08,"d":"0.00"},{"v":3.54423360715103e-07,"d":"0.00"},"up","yes"]
["ENSAPLG00000005956","KIAA1841","ENSAPLT00000006183;ENSAPLT00000006180","NA","NA","NA","NA","KIAA1841 [Source:HGNC Symbol;Acc:HGNC:29387]","NA",{"v":0.565809021246459,"d":"0.57"},{"v":0.743788923512748,"d":"0.74"},{"v":0.788029617563739,"d":"0.79"},{"v":1.79014568271955,"d":"1.79"},{"v":1.50861910623229,"d":"1.51"},{"v":0.670033461756374,"d":"0.67"},{"v":0.741920538243626,"d":"0.74"},{"v":1.20607986827195,"d":"1.21"},{"v":0.121914371104816,"d":"0.12"},{"v":0.0718376373937677,"d":"0.07"},{"v":0.0629994447592068,"d":"0.06"},{"v":0.224790201133144,"d":"0.22"},{"v":0.287562604815864,"d":"0.29"},{"v":0.16227021388102,"d":"0.16"},{"v":0.193214045325779,"d":"0.19"},{"v":0.154830589235127,"d":"0.15"},{"v":6.26411327737272,"d":"6.26"},{"v":2.64711030190517,"d":"2.65"},{"v":8.32368254924044e-08,"d":"0.00"},{"v":4.57405754493483e-07,"d":"0.00"},"up","yes"]
["ENSAPLG00000025438","ENSAPLG00000025438","ENSAPLT00000020172","GO:0015018(galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity);GO:0016020(membrane)","00515(Mannose type O-glycan biosyntheis)","K00735","EC:2.4.1.135",null,"NA",{"v":4.596461,"d":"4.60"},{"v":2.861467,"d":"2.86"},{"v":8.161313,"d":"8.16"},{"v":3.821177,"d":"3.82"},{"v":4.694901,"d":"4.69"},{"v":5.064617,"d":"5.06"},{"v":4.884457,"d":"4.88"},{"v":3.112567,"d":"3.11"},{"v":6.159077,"d":"6.16"},{"v":11.43674,"d":"11.44"},{"v":5.82383,"d":"5.82"},{"v":3.640087,"d":"3.64"},{"v":9.439651,"d":"9.44"},{"v":9.156816,"d":"9.16"},{"v":5.511663,"d":"5.51"},{"v":11.018778,"d":"11.02"},{"v":0.598150323022748,"d":"0.60"},{"v":-0.74141999670814,"d":"-0.74"},{"v":8.90284944358574e-08,"d":"0.00"},{"v":4.86654704832466e-07,"d":"0.00"},"down","no"]
["ENSAPLG00000011673","SYTL2","ENSAPLT00000027392;ENSAPLT00000046695;ENSAPLT00000046608;ENSAPLT00000012246","GO:0001786(phosphatidylserine binding);GO:0005546(phosphatidylinositol-4,5-bisphosphate binding);GO:0005737(cytoplasm);GO:0005886(plasma membrane);GO:0006886(intracellular protein transport);GO:0006887(exocytosis);GO:0006904(vesicle docking involved in exocytosis);GO:0010923(negative regulation of phosphatase activity);GO:0016020(membrane);GO:0017137(Rab GTPase binding);GO:0019897(extrinsic component of plasma membrane);GO:0019902(phosphatase binding);GO:0042043(neurexin family protein binding);GO:0042470(melanosome);GO:0070257(positive regulation of mucus secretion);GO:0070382(exocytic vesicle);GO:0072659(protein localization to plasma membrane);GO:0072659(protein localization to plasma membrane)","NA","NA","NA","synaptotagmin like 2 [Source:HGNC Symbol;Acc:HGNC:15585]","NA",{"v":0.294681,"d":"0.29"},{"v":0.233952,"d":"0.23"},{"v":0.456579,"d":"0.46"},{"v":1.15251069380654,"d":"1.15"},{"v":0.734852,"d":"0.73"},{"v":0.306081,"d":"0.31"},{"v":0.321304,"d":"0.32"},{"v":0.312196,"d":"0.31"},{"v":1.18063306680585,"d":"1.18"},{"v":0.882375749478079,"d":"0.88"},{"v":0.917927801670146,"d":"0.92"},{"v":2.27112304384134,"d":"2.27"},{"v":1.631302,"d":"1.63"},{"v":1.186917,"d":"1.19"},{"v":0.960303909533751,"d":"0.96"},{"v":0.500021,"d":"0.50"},{"v":0.39999100427119,"d":"0.40"},{"v":-1.32196054048556,"d":"-1.32"},{"v":1.03380297361412e-07,"d":"0.00"},{"v":5.59504739240818e-07,"d":"0.00"},"down","yes"]
["ENSAPLG00000010621","HECTD2","ENSAPLT00000028271;ENSAPLT00000039584;ENSAPLT00000032346;ENSAPLT00000011065","GO:0004842(ubiquitin-protein transferase activity);GO:0004842(ubiquitin-protein transferase activity)","NA","NA","NA","HECT domain E3 ubiquitin protein ligase 2 [Source:HGNC Symbol;Acc:HGNC:26736]","NA",{"v":0.944736668885191,"d":"0.94"},{"v":0.489509916805324,"d":"0.49"},{"v":0.959266961730449,"d":"0.96"},{"v":2.07541201996672,"d":"2.08"},{"v":1.01781374542429,"d":"1.02"},{"v":1.39424274542429,"d":"1.39"},{"v":1.13668875124792,"d":"1.14"},{"v":0.733203632279534,"d":"0.73"},{"v":2.51859059816972,"d":"2.52"},{"v":0.952117975873544,"d":"0.95"},{"v":3.79602878369384,"d":"3.80"},{"v":2.46830980033278,"d":"2.47"},{"v":4.02235417138103,"d":"4.02"},{"v":2.66248194342762,"d":"2.66"},{"v":2.0033106921797,"d":"2.00"},{"v":0.899301160565724,"d":"0.90"},{"v":0.452885322773817,"d":"0.45"},{"v":-1.14278230998055,"d":"-1.14"},{"v":1.27272993133016e-07,"d":"0.00"},{"v":6.81702273492537e-07,"d":"0.00"},"down","yes"]
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["ENSAPLG00000009408","RNF150","ENSAPLT00000009815","NA","NA","NA","NA","ring finger protein 150 [Source:HGNC Symbol;Acc:HGNC:23138]","NA",{"v":9.177194,"d":"9.18"},{"v":6.315767,"d":"6.32"},{"v":10.712891,"d":"10.71"},{"v":12.35193,"d":"12.35"},{"v":11.11795,"d":"11.12"},{"v":17.854786,"d":"17.85"},{"v":10.328199,"d":"10.33"},{"v":6.587453,"d":"6.59"},{"v":15.251204,"d":"15.25"},{"v":12.841702,"d":"12.84"},{"v":11.686627,"d":"11.69"},{"v":11.673628,"d":"11.67"},{"v":13.462032,"d":"13.46"},{"v":12.988363,"d":"12.99"},{"v":16.338257,"d":"16.34"},{"v":15.030145,"d":"15.03"},{"v":0.772807329031296,"d":"0.77"},{"v":-0.371819318639443,"d":"-0.37"},{"v":3.36650699433743e-06,"d":"0.00"},{"v":1.46446583087005e-05,"d":"0.00"},"down","no"]
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["ENSAPLG00000013360","MT4","ENSAPLT00000013914","GO:0006875(cellular metal ion homeostasis);GO:0046872(metal ion binding)","NA","NA","NA","metallothionein 4 [Source:HGNC Symbol;Acc:HGNC:18705]","NA",{"v":41.605244,"d":"41.61"},{"v":13.643873,"d":"13.64"},{"v":4.896884,"d":"4.90"},{"v":6.270225,"d":"6.27"},{"v":3.43169,"d":"3.43"},{"v":5.403085,"d":"5.40"},{"v":18.25366,"d":"18.25"},{"v":6.538217,"d":"6.54"},{"v":13.433075,"d":"13.43"},{"v":11.910501,"d":"11.91"},{"v":47.294487,"d":"47.29"},{"v":55.049362,"d":"55.05"},{"v":22.765373,"d":"22.77"},{"v":13.084106,"d":"13.08"},{"v":30.838747,"d":"30.84"},{"v":24.226572,"d":"24.23"},{"v":0.457648035903093,"d":"0.46"},{"v":-1.1276896058785,"d":"-1.13"},{"v":0.000960007313156218,"d":"0.00"},{"v":0.00264263090315621,"d":"0.00"},"down","yes"]
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proliferation);GO:0009898(cytoplasmic side of plasma membrane);GO:0010719(negative regulation of epithelial to mesenchymal transition);GO:0010975(regulation of neuron projection development);GO:0010997(anaphase-promoting complex binding);GO:0016311(dephosphorylation);GO:0016314(phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity);GO:0016324(apical plasma membrane);GO:0016477(cell migration);GO:0019899(enzyme binding);GO:0019901(protein kinase binding);GO:0021542(dentate gyrus development);GO:0021955(central nervous system neuron axonogenesis);GO:0030165(PDZ domain binding);GO:0030336(negative regulation of cell migration);GO:0030534(adult behavior);GO:0031642(negative regulation of myelination);GO:0031647(regulation of protein stability);GO:0032228(regulation of synaptic transmission, GABAergic);GO:0032286(central nervous system myelin maintenance);GO:0032535(regulation of cellular component size);GO:0033032(regulation of myeloid cell apoptotic process);GO:0033555(multicellular organismal response to stress);GO:0035176(social behavior);GO:0035749(myelin sheath adaxonal region);GO:0036294(cellular response to decreased oxygen levels);GO:0042711(maternal behavior);GO:0042802(identical protein binding);GO:0042995(cell projection);GO:0043005(neuron projection);GO:0043066(negative regulation of apoptotic process);GO:0043220(Schmidt-Lanterman incisure);GO:0043491(protein kinase B signaling);GO:0043542(endothelial cell migration);GO:0045475(locomotor rhythm);GO:0045736(negative regulation of cyclin-dependent protein serine/threonine kinase activity);GO:0045792(negative regulation of cell size);GO:0046621(negative regulation of organ growth);GO:0046855(inositol phosphate dephosphorylation);GO:0046856(phosphatidylinositol dephosphorylation);GO:0048679(regulation of axon regeneration);GO:0048681(negative regulation of axon regeneration);GO:0048738(cardiac muscle tissue development);GO:0048853(forebrain morphogenesis);GO:0048854(brain morphogenesis);GO:0050680(negative regulation of epithelial cell proliferation);GO:0050771(negative regulation of axonogenesis);GO:0050821(protein stabilization);GO:0051091(positive regulation of DNA-binding transcription factor activity);GO:0051548(negative regulation of keratinocyte migration);GO:0051717(inositol-1,3,4,5-tetrakisphosphate 3-phosphatase activity);GO:0051726(regulation of cell cycle);GO:0051800(phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity);GO:0051895(negative regulation of focal adhesion assembly);GO:0051898(negative regulation of protein kinase B signaling);GO:0060024(rhythmic synaptic transmission);GO:0060044(negative regulation of cardiac muscle cell proliferation);GO:0060070(canonical Wnt signaling pathway);GO:0060074(synapse maturation);GO:0060134(prepulse inhibition);GO:0060179(male mating behavior);GO:0060291(long-term synaptic potentiation);GO:0060341(regulation of cellular localization);GO:0060736(prostate gland growth);GO:0060997(dendritic spine morphogenesis);GO:0061002(negative regulation of dendritic spine morphogenesis);GO:0070373(negative regulation of ERK1 and ERK2 cascade);GO:0070374(positive regulation of ERK1 and ERK2 cascade);GO:0071257(cellular response to electrical stimulus);GO:0071456(cellular response to hypoxia);GO:0090071(negative regulation of ribosome biogenesis);GO:0090344(negative regulation of cell aging);GO:0090394(negative regulation of excitatory postsynaptic potential);GO:0097105(presynaptic membrane assembly);GO:0097107(postsynaptic density assembly);GO:1903690(negative regulation of wound healing, spreading of epidermal cells);GO:1903984(positive regulation of TRAIL-activated apoptotic signaling pathway);GO:1904668(positive regulation of ubiquitin protein ligase activity);GO:1904706(negative regulation of vascular smooth muscle cell proliferation);GO:1990381(ubiquitin-specific protease binding);GO:2000060(positive regulation of ubiquitin-dependent protein catabolic process);GO:2000134(negative regulation of G1/S transition of mitotic cell cycle);GO:2000463(positive regulation of excitatory postsynaptic potential);GO:2000808(negative regulation of synaptic vesicle clustering);GO:2001235(positive regulation of apoptotic signaling pathway);GO:2001235(positive regulation of apoptotic signaling pathway)","00562(Inositol phosphate metabolism);04068(FoxO signaling pathway);04070(Phosphatidylinositol signaling system);04150(mTOR signaling pathway);04140(Autophagy - animal);04115(p53 signaling pathway);04218(Cellular senescence);04510(Focal adhesion);04510(Focal adhesion)","K01110","EC:3.1.3.16;EC:3.1.3.48","phosphatase and tensin homolog [Source:HGNC 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apparatus);GO:0005829(cytosol);GO:0006511(ubiquitin-dependent protein catabolic process);GO:0006513(protein monoubiquitination);GO:0007612(learning);GO:0007626(locomotory behavior);GO:0008013(beta-catenin binding);GO:0008344(adult locomotory behavior);GO:0010498(proteasomal protein catabolic process);GO:0010506(regulation of autophagy);GO:0010628(positive regulation of gene expression);GO:0010629(negative regulation of gene expression);GO:0010636(positive regulation of mitochondrial fusion);GO:0010821(regulation of mitochondrion organization);GO:0010994(free ubiquitin chain polymerization);GO:0015631(tubulin binding);GO:0016235(aggresome);GO:0016567(protein ubiquitination);GO:0016607(nuclear speck);GO:0019538(protein metabolic process);GO:0019899(enzyme binding);GO:0019900(kinase binding);GO:0019901(protein kinase binding);GO:0030165(PDZ domain binding);GO:0030544(Hsp70 protein binding);GO:0031072(heat shock protein binding);GO:0031396(regulation of protein ubiquitination);GO:0031624(ubiquitin conjugating enzyme binding);GO:0031625(ubiquitin protein ligase binding);GO:0031647(regulation of protein stability);GO:0031648(protein destabilization);GO:0032092(positive regulation of protein binding);GO:0032232(negative regulation of actin filament bundle assembly);GO:0032436(positive regulation of proteasomal ubiquitin-dependent protein catabolic process);GO:0032991(protein-containing complex);GO:0033132(negative regulation of glucokinase activity);GO:0034976(response to endoplasmic reticulum stress);GO:0035249(synaptic transmission, glutamatergic);GO:0042053(regulation of dopamine metabolic process);GO:0042415(norepinephrine metabolic process);GO:0042417(dopamine metabolic process);GO:0042802(identical protein binding);GO:0042826(histone deacetylase binding);GO:0043005(neuron projection);GO:0043123(positive regulation of I-kappaB kinase/NF-kappaB signaling);GO:0043130(ubiquitin binding);GO:0043161(proteasome-mediated ubiquitin-dependent protein catabolic process);GO:0043274(phospholipase binding);GO:0043388(positive regulation of DNA binding);GO:0043524(negative regulation of neuron apoptotic process);GO:0044257(cellular protein catabolic process);GO:0044828(negative regulation by host of viral genome replication);GO:0045944(positive regulation of transcription by RNA polymerase II);GO:0046676(negative regulation of insulin secretion);GO:0046928(regulation of neurotransmitter secretion);GO:0048471(perinuclear region of cytoplasm);GO:0050804(modulation of chemical synaptic transmission);GO:0050821(protein stabilization);GO:0051087(chaperone binding);GO:0051582(positive regulation of neurotransmitter uptake);GO:0051583(dopamine uptake involved in synaptic transmission);GO:0051865(protein autoubiquitination);GO:0051881(regulation of mitochondrial membrane potential);GO:0060548(negative regulation of cell death);GO:0061630(ubiquitin protein ligase activity);GO:0061734(parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization);GO:0070534(protein K63-linked ubiquitination);GO:0070585(protein localization to mitochondrion);GO:0070842(aggresome assembly);GO:0070936(protein K48-linked ubiquitination);GO:0070979(protein K11-linked ubiquitination);GO:0071797(LUBAC complex);GO:0085020(protein K6-linked ubiquitination);GO:0090090(negative regulation of canonical Wnt signaling pathway);GO:0090201(negative regulation of release of cytochrome c from mitochondria);GO:0097237(cellular response to toxic substance);GO:0097602(cullin family protein binding);GO:0098779(positive regulation of mitophagy in response to mitochondrial depolarization);GO:0099073(mitochondrion-derived vesicle);GO:0099074(mitochondrion to lysosome transport);GO:1900407(regulation of cellular response to oxidative stress);GO:1901215(negative regulation of neuron death);GO:1901800(positive regulation of proteasomal protein catabolic process);GO:1902236(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway);GO:1902254(negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator);GO:1902283(negative regulation of primary amine oxidase activity);GO:1902530(positive regulation of protein linear polyubiquitination);GO:1903265(positive regulation of tumor necrosis factor-mediated signaling pathway);GO:1903377(negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway);GO:1903382(negative regulation of endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway);GO:1903542(negative regulation of exosomal secretion);GO:1903599(positive regulation of autophagy of mitochondrion);GO:1903861(positive regulation of dendrite extension);GO:1904049(negative regulation of spontaneous neurotransmitter secretion);GO:1905366(negative regulation of intralumenal vesicle formation);GO:1905477(positive regulation of protein localization to membrane);GO:1990381(ubiquitin-specific protease binding);GO:1990444(F-box domain binding);GO:1990452(Parkin-FBXW7-Cul1 ubiquitin ligase complex);GO:2000377(regulation of reactive oxygen species metabolic process);GO:2000378(negative regulation of reactive oxygen species metabolic process);GO:2000378(negative regulation of reactive oxygen species metabolic process)","04141(Protein processing in endoplasmic reticulum);04120(Ubiquitin mediated proteolysis);04137(Mitophagy - animal);04137(Mitophagy - animal)","K04556","EC:2.3.2.31","parkin RBR E3 ubiquitin protein ligase [Source:HGNC 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