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["Table 1 Demographic characteristics of healthy children in Hainan provice "]
["Variable","Haikou\n（N=764）","Wanning（N=645）","Baisha (N=450)","Qiongzhong (N=474)","Total  (N=2333)","P Value"]
["Mean age (months) ± SD","30.0±17.2","32.5±18.4","30.0±17.1","29.9±17.2","30.7±17.5",0.1107]
["Age group <12 months",148,109,88,98,443,0.5802]
["Age group 12–23 months",156,125,91,95,467]
["Age group 24–35 months",151,118,93,93,455]
["Age group 36–47 months",152,126,88,94,460]
["Age group ≥48 monthsa",157,167,90,94,508]
["Gender "]
["male",430,355,232,242,1259,0.2019]
["female",334,290,218,232,1074]
["Number of swabs positive for pneumococcus n (%)","213 (27.9)","221 (34.3)","145 (32.2)","131 (27.6)","710 (30.4)",0.0261]
["PCV13 immunization   n (%)","233（30.5）","42（6.5）","30（6.7）","22（4.6）","327（14.0）","-"]
["1 dose",41,16,7,11,75]
["2 doses",29,12,10,6,57]
["3 doses",63,4,9,4,80]
["4 doses",100,10,4,1,115]
["aSixty children aged ≥60 months"]
["Abbreviations: SD, standard deviation;  PCV13,13-valent pneumococcal conjugate vaccine."]

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