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["Additional Table 5 Impact of SNP3 (rs4149117) on Biochemical Parameters in Han Population"]
[null,"rs4149117(SNP3)",{"$nulls":7},"Pvalue"]
[null,"GG","GT","TT","GG+GT","GT+TT","GG+TT","G","T","Genotypes      (GG、GT、TT）","Dominantmodel（GG+GTvsTT)","Recessivemodel(GT+TTvsGG)","Additivemodel(GG+TTvsGT）","Alleles（GvsT）"]
["At baseline"]
["LDL-C(mmol/L)","3.47±0.72","3.65±0.79","3.58±0.66","3.54±0.75","3.64±0.77","3.48±0.72","3.52±0.74","3.64±0.76",0.066,0.819,0.022,0.025,0.05]
["TG (mmol/L)","2±1.12","2.27±1.5","2.86±1.87","2.11±1.29","2.35±1.56","2.08±1.23","2.07±1.23","2.41±1.6",0.005,0.009,0.009,0.162,0.002]
["TC (mmol/L)","5.04±0.9","5.3±1","5.24±0.98","5.14±0.95","5.29±0.99","5.05±0.91","5.1±0.93","5.28±0.99",0.027,0.639,0.007,0.012,0.018]
["HDL-C (mmol/L)","1.12±0.3","1.13±0.38","1.03±0.35","1.12±0.33","1.12±0.37","1.11±0.3","1.12±0.32","1.11±0.37",0.391,0.186,0.98,0.545,0.6]
["ApoAI (g/L)","1.24±0.3","1.25±0.24","1.19±0.28","1.24±0.28","1.24±0.25","1.24±0.3","1.24±0.29","1.23±0.25",0.643,0.349,0.856,0.793,0.613]
["ApoB (g/L)","1.09±0.25","1.12±0.25","1.05±0.27","1.1±0.25","1.11±0.25","1.08±0.26","1.09±0.25","1.1±0.25",0.288,0.327,0.364,0.161,0.715]
["Lp(a) (mg/dL)","159.5(84.7,282.6)","178(99.1,280)","121.8(93.8,236.2)","164.4(90.1,280.7)","172.9(96.8,275.3)","154.1(87.5,277.8)","161.1(87.2,281.3)","154.7(96.2,270.5)",0.45,0.498,0.405,0.239,0.675]
["ALT (U/L)","21.5(15.5,29.5)","20(13.5,29.9)","22.1(15.2,37.1)","20.4(14.6,29.8)","20.2(14,31.7)","21.5(15.4,30.5)","20.7(14.9,29.6)","20.4(14.4,32.1)",0.354,0.374,0.398,0.2,0.721]
["AST (U/L)","20.5(16.6,26.9)","19.7(16.3,25.7)","20.5(17,32.2)","20.2(16.5,26.4)","19.8(16.3,26.3)","20.5(16.7,27.1)","20.3(16.5,26.5)","19.8(16.3,26.5)",0.487,0.593,0.377,0.248,0.602]
["Tbil","11.6(8.6,15.3)","12(9.5,15.9)","13(8.9,20.5)","11.8(8.7,15.4)","12.1(9.4,16.1)","11.7(8.6,15.3)","11.7(8.7,15.3)","12.3(9.4,16.3)",0.287,0.218,0.196,0.457,0.129]
["After treatment"]
["LDL-C(mmol/L)","2.26±0.75","2.4±0.78","2.22±0.72","2.32±0.76","2.38±0.77","2.26±0.74","2.3±0.76","2.36±0.77",0.202,0.571,0.142,0.076,0.327]
["TG (mmol/L)","1.77±1.11","2.05±1.5","2.08±2.16","1.88±1.29","2.05±1.6","1.79±1.24","1.84±1.22","2.05±1.66",0.109,0.492,0.035,0.069,0.048]
["TC (mmol/L)","3.79±0.97","3.98±1.08","3.98±1.1","3.87±1.02","3.98±1.08","3.81±0.98","3.84±1","3.98±1.08",0.177,0.602,0.063,0.098,0.086]
["HDL-C (mmol/L)","1.1±0.27","1.07±0.29","1.07±0.35","1.09±0.28","1.07±0.3","1.09±0.28","1.09±0.28","1.07±0.31",0.661,0.748,0.363,0.438,0.388]
["ApoAI (g/L)","1.18±0.23","1.19±0.26","1.14±0.31","1.18±0.25","1.18±0.27","1.17±0.24","1.18±0.24","1.18±0.27",0.749,0.505,0.865,0.626,0.911]
["ApoB (g/L)","0.82±0.25","0.85±0.26","0.78±0.2","0.83±0.25","0.84±0.25","0.81±0.25","0.83±0.25","0.84±0.25",0.293,0.375,0.32,0.151,0.633]
["Lp(a) (mg/dL)","159.9(82.2,304.8)","174.1(86.7,304.5)","111.8(53.9,241.1)","165.2(86.1,303.9)","168.7(83.4,299.1)","155(75.2,296.5)","161(85.7,303.4)","152(80.3,294)",0.223,0.132,0.684,0.261,0.815]
["ALT (U/L)","23(15.7,31.1)","19.9(14,28.2)","17.3(14.9,25)","21.5(14.7,29.9)","19.8(14.1,27.9)","22.6(15.6,30.8)","22(15,30)","19.1(14.1,27.3)",0.045,0.373,0.013,0.034,0.018]
["AST (U/L)","20.5(16.5,25.6)","19.6(15.5,23.5)","17.4(15.6,21.7)","20.2(16,24.9)","19.2(15.6,23.5)","20.3(16.4,25.4)","20.4(16.2,25.2)","19(15.7,23.3)",0.022,0.087,0.01,0.069,0.006]
["Tbil","10.8(8.2,14.7)","11.4(8.4,15.7)","11.6(8.2,17.9)","11.1(8.3,14.8)","11.4(8.3,15.9)","10.8(8.2,14.8)","11(8.2,14.8)","11.4(8.3,16)",0.421,0.279,0.308,0.595,0.215]
["Changes [%] "]
["LDL-C","-34.37±17.21","-33.72±17.55","-37.19±18.99","-34.11±17.32","-34.18±17.73","-34.62±17.36","-34.21±17.27","-34.53±17.85",0.671,0.411,0.915,0.616,0.821]
["TG ","-2.8±50.6","-1.7±54.8","-3.5±107.4","-2.37±52.28","-1.94±63.79","-2.87±57.78","-2.53±51.62","-2.12±69.88",0.979,0.926,0.88,0.843,0.93]
["TC ","-23.5±20.9","-23.8±18.9","-21.6±25.9","-23.62±20.1","-23.55±19.87","-23.31±21.36","-23.57±20.39","-23.32±20.6",0.887,0.646,0.972,0.798,0.884]
["HDL-C ","1±23.7","-2.1±24.8","6±24.9","-0.23±24.19","-0.99±24.92","1.44±23.84","0.22±24.01","-0.18±24.96",0.238,0.23,0.419,0.161,0.84]
["ApoAI ","-2.8±20.2","-2.5±23.6","-2.8±16.8","-2.68±21.64","-2.51±22.83","-2.83±19.93","-2.74±21.11","-2.54±22.2",0.986,0.977,0.88,0.867,0.911]
["ApoB ","-22.6±25","-21.7±25.6","-21±28.8","-22.2±25.18","-21.57±25.94","-22.43±25.26","-22.34±25.08","-21.51±26.2",0.922,0.828,0.7,0.77,0.692]
["Lp(a)","90.6±843.3","28.2±118.2","0.9±89.7","65.59±657.04","24.72±115.13","82.58±805.39","74.96±731.79","22.01±112.59",0.587,0.645,0.31,0.412,0.316]
["ALT ","19±72.5","13.1±71.3","-5.7±53.5","16.6±72.01","10.77±69.56","16.86±71.35","17.48±72.15","8.98±68.07",0.277,0.163,0.257,0.607,0.149]
["AST ","15.7±114","6.4±88.8","-13.5±44.9","11.98±104.72","3.95±84.81","13.19±110.13","13.36±108.23","2.04±81.51",0.375,0.268,0.26,0.523,0.183]
["Tbil","5.8±47.5","48.5±556.2","7.4±44.4","22.69±351.79","43.46±521.14","5.9±47.16","16.32±279.25","39.51±492",0.485,0.842,0.277,0.229,0.413]

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