Column Name	Description
Variable	Variable Code
Variable_Name	Name of the Variable
Outcome	Outcome Code
Outcome_Name	Name of the Outcome
Variable_type_df	Type of variable assigned in the discovery female cohort
Weight_df	Weight used in the discovery female cohort
Converged_df	Whether linear regression converged in the discovery female cohort
N_df	Number of observations in the discovery female cohort
Beta_df	Beta coefficient in the discovery female cohort
SE_df	Standard error in the discovery female cohort
Beta_pvalue_df	P-value associated with the beta coefficient in the discovery female cohort
LRT_pvalue_df	Likelihood ration test in the discovery female cohort (for categorical variables only)
pvalue_df	P-value used in the discovery female cohort. If present, this is equal to the LRT_pvalue. If not, this is equal to the Beta_pvalue.
Variable_type_dm	Type of variable assigned in the discovery male cohort
Weight_dm	Weight used in the discovery male cohort
Converged_dm	Whether linear regression converged in the discovery male cohort
N_dm	Number of observations in the discovery male cohort
Beta_dm	Beta coefficient in the discovery male cohort
SE_dm	Standard error in the discovery male cohort
Beta_pvalue_dm	P-value associated with the beta coefficient in the discovery male cohort
LRT_pvalue_dm	Likelihood ration test in the discovery male cohort (for categorical variables only)
pvalue_dm	P-value used in the discovery male cohort. If present, this is equal to the LRT_pvalue. If not, this is equal to the Beta_pvalue.
Variable_type_rf	Type of variable assigned in the replication female cohort
Weight_rf	Weight used in the replication female cohort
Converged_rf	Whether linear regression converged in the replication female cohort
N_rf	Number of observations in the replication female cohort
Beta_rf	Beta coefficient in the replication female cohort
SE_rf	Standard error in the replication female cohort
Beta_pvalue_rf	P-value associated with the beta coefficient in the replication female cohort
LRT_pvalue_rf	Likelihood ration test in the replication female cohort (for categorical variables only)
pvalue_rf	P-value used in the replication female cohort. If present, this is equal to the LRT_pvalue. If not, this is equal to the Beta_pvalue.
Variable_type_rm	Type of variable assigned in the replication male cohort
Weight_rm	Weight used in the replication male cohort
Converged_rm	Whether linear regression converged in the replication male cohort
N_rm	Number of observations in the replication male cohort
Beta_rm	Beta coefficient in the replication male cohort
SE_rm	Standard error in the replication male cohort
Beta_pvalue_rm	P-value associated with the beta coefficient in the replication male cohort
LRT_pvalue_rm	Likelihood ration test in the replication male cohort (for categorical variables only)
pvalue_rm	P-value used in the replication male cohort. If present, this is equal to the LRT_pvalue. If not, this is equal to the Beta_pvalue.
SE_female	Standard error in the female cohort (meta-analysis of the female replication and discovery cohorts).
Beta_female	Beta coefficient in the female cohort (meta-analysis of the female replication and discovery cohorts).
pvalue_female	P-value in the female cohort (meta-analysis of the female replication and discovery cohorts).
N_female	Number of observations in the female cohort (meta-analysis of the female replication and discovery cohorts).
SE_male	Standard error in the male cohort (meta-analysis of the female replication and discovery cohorts).
Beta_male	Beta coefficient in the male cohort (meta-analysis of the female replication and discovery cohorts).
pvalue_male	P-value in the male cohort (meta-analysis of the female replication and discovery cohorts).
N_male	Number of observations in the male cohort (meta-analysis of the female replication and discovery cohorts).
SE_total	Standard error in all cohorts (meta-analysis of the female and male cohorts).
Beta_total	Beta coefficient in all cohorts (meta-analysis of the female and male cohorts).
pvalue_total	P-value in all cohorts (meta-analysis of the female and male cohorts).
N_total	Number of observations in all cohort (meta-analysis of the female and male cohorts).
SE_SD	Square root of the sum of square SE of male and female cohorts. This is the denominator of the sex difference test.
Beta_SD	Difference between beta coefficients in the male and female cohorts. This is the numerator of the sex difference test.
pvalue_SD	P-value of the sex difference test.
pvalue_bonferroni_SD	Bonferroni-corrected p-value of the sex difference test. This is a corrected p-value taking all tests into consideration, and does not reflect the dual strategy employed in the paper.
difference_type	Type of sex difference.
Variable_Category	Category of the variable (exposure).