{"text_format":"3","workbook":"xls","n_sheets":18,"sheets":["Table S1","Table S2","Table S3","Table S4","Table S5","Table S6","Table S7","Table S8","Table S9","Table S10","Table S11","Table S12","Table S13","Table S14","Table S15","Table S16","Table S17","Table S18"],"read":"whole","date_system":"1900","formulas":"cached_only"}

{"sheet":"Table S1","index":0,"n_rows":16,"n_cols":8,"rows_kept":16,"flags":["formulas_cached_only"]}
["Supplementary table S1. Summary statistics of exposure."]
["Supplementary table S1. Summary statistics of exposure."]
["Exposure","SNPs(n)","Sample","Population","PMID","GWAS ID"]
["HDL cholesterol",290,{"v":403943,"d":"403,943"},"European",32203549,"ieu-b-109"]
["LDL cholesterol",140,{"v":440546,"d":"440,546"},"European",32203549,"ieu-b-110",null,"‘"]
["triglycerides",249,{"v":441016,"d":"441,016"},"European",32203549,"ieu-b-111"]
["apolipoprotein A-I",251,{"v":393193,"d":"393,193"},"European",32203549,"ieu-b-107"]
["apolipoprotein B",149,{"v":439214,"d":"439,214"},"European",32203549,"ieu-b-108"]
["circulating leptin levels",3,{"v":49909,"d":"49,909"},"European",32917775,"ebi-a-GCST90007310"]
["Atherosclerosis, excluding cerebral, coronary and PAD",27,{"v":213140,"d":"213,140"},"European","FinnGen","finn-b-I9_ATHSCLE"]
["Body mass index",138,{"v":315347,"d":"315,347"},"European",30108127,"ebi-a-GCST006368"]
[]
[]
[]
[]
[{"$nulls":5}," "]

{"sheet":"Table S2","index":1,"n_rows":292,"n_cols":10,"rows_kept":292,"flags":["formulas_cached_only"]}
["Supplementary table S2: The characteristics of SNPs adopted as instrumental variables of HDL cholesterol || id:ieu-b-109"]
["SNP","Chr","Pos","EA","NEA","Beta","SE","P value","R^2","F"]
["rs3768321","1",40035928,"T","G",-0.0452296,0.00239482,1.50003e-79,0.000279046623051947,112.749834422772]
["rs12045101","1",110267651,"T","C",-0.0145519,0.00222909,6.70039e-11,3.8581309995561e-05,15.5851742373555]
["rs2642438","1",220970028,"G","A",0.0276562,0.00207854,2.09991e-40,0.000183123760683516,73.9847433787008]
["rs1771582","1",161614490,"G","T",0.0129458,0.00197832,6.00067e-11,5.23061292205591e-05,21.1296953560576]
["rs4650994","1",178515312,"A","G",-0.018056,0.00190061,2.09991e-21,0.000111260770037132,44.9477876350327]
["rs61805075","1",182136401,"A","G",-0.0257183,0.00202534,6.00067e-37,0.000176161439478624,71.1713656746617]
["rs2298632","1",23710475,"T","C",0.0144252,0.00193744,9.70063e-14,6.86168267312947e-05,27.7190516000267]
["rs771481","1",93846653,"A","T",0.0288148,0.0024568,9.09913e-32,0.000102183372339133,41.2802717634214]
["rs3747973","1",205677148,"G","A",0.0141665,0.00193802,2.70023e-13,6.38734714206765e-05,25.8027620311227]
["rs2298214","1",935222,"A","C",-0.01241,0.00194099,1.6e-10,4.93881535104014e-05,19.9508854545386]
["rs57760538","1",25183636,"G","GT",0.0125354,0.0022762,3.59998e-08,2.72184000603637e-05,10.9949270031052]
["rs1168114","1",63156043,"G","A",0.0155365,0.00199819,7.50067e-15,6.78818946118436e-05,27.4221418583464]
["rs6693842","1",66078405,"C","T",0.013664,0.00199336,7.10068e-12,5.39115416334769e-05,21.7782561383308]
["rs2516331","1",212416989,"A","C",0.0126835,0.00196658,1.09999e-10,4.82967992365226e-05,19.5099996509364]
["rs2281718","1",230297778,"T","A",0.0596431,0.00195409,1e-200,0.00109468233875762,442.671663451941]
["rs12740374","1",109817590,"T","G",0.0288629,0.00229106,2.19989e-36,0.000135287572638948,54.6555916016684]
["rs140584594","1",110232983,"G","A",0.031071,0.00212905,3.10027e-48,0.000207958810461421,84.0205626728645]
["rs267738","1",150940625,"G","T",0.0214529,0.00229757,9.8992e-21,7.39169637172204e-05,29.8602994235668]
["rs12046972","1",219673143,"C","T",-0.0148213,0.00191599,1e-14,7.28522293945786e-05,29.4301464456555]
["rs557933","1",234853268,"C","A",0.0152472,0.00190783,1.29987e-15,7.89279520773429e-05,31.8847524882903]
["rs676210","2",21231524,"A","G",0.0592694,0.00235237,4.4978e-140,0.000512669295704473,207.194370167989]
["rs7583067","2",100796850,"T","C",0.0145946,0.00223535,6.59933e-11,3.85096137967248e-05,15.5562109703394]
["rs17713879","2",254215,"A","G",0.0138956,0.00197564,1.99986e-12,5.67493613514895e-05,22.9246947354674]
["rs13402475","2",3639909,"G","C",-0.0249227,0.00249807,1.9002e-23,7.42696613898195e-05,30.0027895884886]
["rs2362541","2",30478453,"G","T",-0.0108666,0.00190325,1.09999e-08,4.03410668862697e-05,16.2960682998879]
["rs13389219","2",165528876,"T","C",0.0277324,0.00194608,4.49987e-46,0.000239770614560277,96.8764099324386]
["rs2364723","2",178126546,"C","G",0.0120956,0.00204641,3.40001e-09,3.75863428542571e-05,15.1832356011904]
["rs12475332","2",227232047,"G","T",0.012897,0.0021638,2.5e-09,3.39296137121033e-05,13.7060271326868]
["rs907866","2",20371380,"A","G",-0.0183154,0.00191879,1.39991e-21,0.00011143833108734,45.0195277987954]
["rs2723065","2",65279414,"G","A",0.0149623,0.00196239,2.39994e-14,6.75868202246714e-05,27.3029330668028]
["rs4599108","2",85543222,"T","C",0.0136654,0.00192434,1.20005e-12,6.23829821816781e-05,25.2006162950465]
["rs1446585","2",136407479,"G","A",0.0167827,0.00217146,1.10002e-14,5.46005199500062e-05,22.0565929305678]
["rs1083470","2",147871114,"A","G",0.0115829,0.00195974,3.40001e-09,4.09241743261696e-05,16.5316284447316]
["rs12998038","2",42602387,"T","C",0.0131918,0.0021847,1.6e-09,3.46199967779211e-05,13.9849202763651]
["rs12986742","2",58975143,"C","T",-0.0106002,0.00191315,2.99999e-08,3.79114388803348e-05,15.3145651299612]
["rs6705285","2",66709468,"T","G",0.0115225,0.00191933,1.89998e-09,4.24884652003604e-05,17.1635623749215]
["rs2196808","2",111839021,"C","T",0.0128638,0.00215716,2.5e-09,3.45437658501115e-05,13.9541253492986]
["rs59037995","2",173916114,"A","AT",-0.01722,0.00254345,1.29987e-11,3.213990944026e-05,12.9830444330804]
["rs59104589","2",242237902,"T","C",0.0150155,0.0019816,3.50026e-14,6.53625325714433e-05,26.4043326234925]
["rs17326656","2",48962291,"T","G",-0.0223923,0.00223885,1.50003e-23,8.99959781950366e-05,36.3563373522249]
["rs11688682","2",121347612,"C","G",0.0147369,0.0022133,2.80027e-11,4.33484151403833e-05,17.5109612326386]
["rs72926946","2",203477868,"A","C",-0.0206565,0.00208041,3.10027e-23,0.000101790956487517,41.1217265744046]
["rs1047891","2",211540507,"A","C",-0.0189073,0.00204367,2.19989e-20,9.15337061168753e-05,36.9776014794634]
["rs78058190","2",219699999,"A","G",-0.0783702,0.00490443,1.80011e-57,6.05241021931156e-05,24.4496461568719]
["rs2943645","2",227099180,"T","C",-0.0434706,0.00198833,5.90201e-106,0.000540743587308745,218.546683118506]
["rs11456863","3",12271918,"A","AT",0.019019,0.00200148,1.99986e-21,0.000101906312905623,41.1683332544607]
["rs13097947","3",15846011,"C","T",0.0159634,0.00203024,3.80014e-15,6.9700929043851e-05,28.1570255497422]
["rs113851927","3",185537636,"G","GT",0.0113346,0.00206879,4.30002e-08,3.1981184159743e-05,12.9189246731799]
["rs4916426","3",196094062,"G","GA",0.014042,0.00220858,2e-10,3.80531412524861e-05,15.371808876285]
["rs7622114","3",36960660,"A","C",0.0115687,0.00193999,2.5e-09,4.28612947815949e-05,17.3141763833901]
["rs2159607","3",52501451,"T","G",-0.0239454,0.00243213,7.19946e-23,7.3601242290659e-05,29.7327477793044]
["rs72964564","3",123054770,"C","A",-0.0125748,0.00220598,1.2e-08,3.01850961677258e-05,12.1933659890123]
["rs6765484","3",50041313,"T","C",0.0225207,0.00190864,3.90032e-32,0.00017182290788615,69.4182448791349]
["rs4855582","3",108867705,"T","C",0.0111652,0.00192369,6.49995e-09,4.08716129762914e-05,16.5103950237316]
["rs1225053","3",131642852,"C","T",-0.0150376,0.00216684,3.90032e-12,4.63888086514479e-05,18.73921104515]
["rs62271373","3",150066540,"A","T",-0.0406667,0.00408672,2.49977e-23,2.76393183863687e-05,11.1649625002615]
["rs6762415","3",133478557,"G","T",-0.0108964,0.00191344,1.2e-08,3.99408395024264e-05,16.1343870704141]
["rs77320712","3",153238877,"T","G",-0.0127407,0.0022658,1.89998e-08,2.8181265006963e-05,11.3838891805755]
["rs10513801","3",185822353,"G","T",-0.0303325,0.00277034,6.70039e-28,7.02415287150101e-05,28.3754264840041]
["rs13087167","3",185878140,"C","G",0.0167458,0.00198206,2.90001e-17,8.210306704589e-05,33.1675181605511]
["rs830620","3",71679148,"T","C",0.0149538,0.00193085,9.60064e-15,7.21168980767194e-05,29.1330729128581]
["rs9647335","3",135880410,"T","A",0.0277595,0.00242471,2.39994e-30,0.000100647264816317,40.6596490796363]
["rs76247316","3",160082284,"C","T",-0.0113866,0.0019083,2.39999e-09,4.39986407772815e-05,17.7736369700842]
["rs2268840","3",185931174,"C","T",0.0173197,0.00226775,2.19989e-14,5.09059922930483e-05,20.5640642669433]
["rs2237035","4",55526251,"T","G",0.0139172,0.00195824,1.20005e-12,5.92638459475666e-05,23.9405160029583]
["rs1471251","4",87976359,"T","A",-0.0193662,0.00195327,3.59998e-23,0.000116630592533947,47.1173735059457]
["rs13137144","4",967445,"A","G",0.0164073,0.00192431,1.50003e-17,8.9451019179548e-05,36.1361665553334]
["rs73243877","4",26047616,"G","A",-0.0253693,0.00254909,2.49977e-23,6.85751101892184e-05,27.7021982662417]
["rs2098918","4",37151533,"T","C",0.0118698,0.00191595,5.80003e-10,4.71255822635923e-05,19.0368519478702]
["rs71269068","4",69361445,"C","T",0.0158824,0.00201914,3.69999e-15,6.92957083654995e-05,27.9933175496373]
["rs13111599","4",83917037,"G","A",0.0127921,0.00216664,3.50002e-09,3.3437594625121e-05,13.5072670609865]
["rs1395221","4",24626903,"T","G",-0.0111888,0.00195359,1e-08,3.89007971229086e-05,15.7142381870165]
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["rs13107325","4",103188709,"T","C",-0.080346,0.00362445,6.99842e-109,0.000168674117428939,68.1458861155601]
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["rs116843064","19",8429323,"A","G",0.206178,0.0069176,3.39625e-195,8.33628065060533e-05,33.6764627873128]
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["rs4803773","19",45444742,"G","A",0.0400846,0.00199508,8.69961e-90,0.000499668025089965,201.937303336416]
["rs7251640","19",18614935,"C","T",0.0141902,0.00242811,5.1e-09,2.64435216789464e-05,10.6819050577033]
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["rs2256609","22",21925017,"G","A",-0.0328881,0.00244058,2.19989e-41,0.000137944095700394,55.7289634427795]
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{"sheet":"Table S3","index":2,"n_rows":142,"n_cols":10,"rows_kept":142,"flags":["formulas_cached_only"]}
["Supplementary table S3: The characteristics of SNPs adopted as instrumental variables of LDL cholesterol || id:ieu-b-110"]
["SNP","Chr","Pos","EA","NEA","Beta","SE","P value","R2","F"]
["rs6667939","1",198994619,"T","C",0.0153061,0.00232969,5.00035e-11,3.96202414114724e-05,17.4551512096805]
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["rs1183851","1",62958658,"C","T",0.024377,0.00213943,4.49987e-30,0.000140916737280564,62.0887724557652]
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["rs472495","1",55521313,"T","G",0.0425743,0.00218093,7.29962e-85,0.000394117224134455,173.694434357406]
["rs4970834","1",109814880,"T","C",-0.105303,0.00268179,1e-200,0.00106258042160477,468.611366518855]
["rs556107","1",234853059,"T","C",0.0351712,0.00208846,1.20005e-63,0.000321183764135316,141.541040871515]
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["rs12471768","2",64928603,"C","T",0.0135999,0.00228112,2.5e-09,3.36183999954653e-05,14.8108823257686]
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["rs17050272","2",121306440,"A","G",-0.0205597,0.00211549,2.49977e-22,0.000103669473890054,45.675699881196]
["rs7569317","2",203527979,"C","T",0.017881,0.00208232,8.9002e-18,8.33745824777389e-05,36.7332346811776]
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["rs9929977","16",71639053,"A","T",0.0167269,0.00216129,1e-14,6.33740102357465e-05,27.9208094189586]
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["rs2611867","17",45664861,"G","A",-0.0265838,0.00209023,4.70002e-37,0.00018343700715785,80.8268995258948]
["rs55714927","17",7080316,"T","C",-0.0264314,0.00265551,2.39994e-23,6.93198824456902e-05,30.540575361248]
["rs35278712","17",29618023,"GAAAT","G",0.0181095,0.00231601,5.30029e-15,5.68995071440901e-05,25.0681628413967]
["rs77542162","17",67081278,"G","A",0.128484,0.0070401,2.09991e-74,3.32494265652164e-05,14.6483224250675]
["rs440677","19",11285390,"A","G",-0.0159238,0.00215434,1.50003e-13,5.82511365227914e-05,25.6636836270353]
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["rs5112","19",45430280,"G","C",0.0277824,0.00222587,9.3994e-36,0.000176026446366079,77.5610475834805]
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["rs1883711","20",39179822,"C","G",0.10277,0.0060919,7.50067e-64,3.93097777120362e-05,17.3183674935478]
["rs6074012","20",44700166,"C","T",0.0116537,0.00208962,2.39999e-08,3.52190131661672e-05,15.5160713969988]
["rs17569873","20",62896110,"T","C",0.0171196,0.00260335,4.79954e-11,3.15636112782812e-05,13.9055984778841]
["rs438568","20",12958687,"G","A",0.0124777,0.00213986,5.49997e-09,3.67479579224176e-05,16.1896873129217]
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["rs200571020","20",39911001,"C","CTTTTTTT",-0.0257721,0.00210448,1.80011e-34,0.000169062581848055,74.4920998844033]
["rs2256814","20",62373983,"A","G",0.0152618,0.00262512,6.1e-09,2.43550045287792e-05,10.7297124373215]
["rs5843957","21",40698345,"TG","T",0.0137065,0.00210922,8.10028e-11,4.69646069360482e-05,20.6909475402528]
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{"sheet":"Table S4","index":3,"n_rows":251,"n_cols":10,"rows_kept":251,"flags":["formulas_cached_only"]}
["Supplementary table S4: The characteristics of SNPs adopted as instrumental variables of Triglycerides || id:ieu-b-111"]
["SNP","Chr","Pos","EA","NEA","Beta","SE","P value","R^2","F"]
["rs11206374","1",40048009,"A","G",0.0250232,0.00237577,6.09958e-26,8.76764992595889e-05,38.6699540906695]
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["rs9425589","1",172355276,"A","G",-0.0137618,0.00200182,6.20012e-12,5.26258186112149e-05,23.2099442113204]
["rs213494","1",54877103,"T","C",0.0156106,0.00207578,5.50047e-14,5.84756633796702e-05,25.7900943025948]
["rs698927","1",93836218,"C","A",-0.0183059,0.00256302,9.20026e-13,3.47031154557246e-05,15.3050908939273]
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["rs10631642","1",178502677,"C","CTTT",0.0131387,0.00219147,2e-09,3.49030735986699e-05,15.3932813728765]
["rs880315","1",10796866,"C","T",-0.011772,0.00210497,2.19999e-08,3.18374119962183e-05,14.0411914492973]
["rs36043408","1",203511492,"A","G",-0.0128072,0.00198554,1.09999e-10,4.71692214195116e-05,20.8032682890726]
["rs61830291","1",221001142,"C","A",0.0287484,0.00337913,1.80011e-17,2.84306468002909e-05,12.5386697504745]
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["rs2131311","1",40435999,"G","A",-0.0124181,0.00222753,2.5e-08,2.87423918523719e-05,12.6761615435842]
["rs1938566","1",98478981,"T","C",-0.0212127,0.00267054,1.99986e-15,3.95108038640436e-05,17.4255061510531]
["rs11240358","1",205070573,"A","G",0.0135651,0.00202953,2.29985e-11,4.83737291944731e-05,21.33452383745]
["rs11118310","1",219637671,"T","A",0.0193178,0.00202011,1.10002e-21,0.000100053041380766,44.1292072528963]
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["rs1473886","2",20368519,"T","G",-0.0181218,0.00198519,6.90081e-20,9.42851974873809e-05,41.585012935857]
["rs954244","2",121309231,"G","C",0.015323,0.00227424,1.59993e-11,3.90736962753222e-05,17.2327204352492]
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["rs676210","2",21231524,"A","G",-0.0735169,0.00244968,7.09578e-198,0.0006663654753631,294.072463488706]
["rs4665972","2",27598097,"C","T",-0.10025,0.00203577,1e-200,0.00262903725432611,1162.49848751114]
["rs10210970","2",28646847,"T","C",0.0232557,0.00292788,1.99986e-15,3.26646300366157e-05,14.4060297185991]
["rs13389219","2",165528876,"T","C",-0.0376242,0.00202704,6.59933e-77,0.000372555921280991,164.363611704599]
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["rs6800707","3",52516293,"G","C",0.0298848,0.00253832,5.30029e-32,9.65317833262413e-05,42.5759778269055]
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["rs2137557","3",188439236,"C","T",0.0117624,0.00208003,1.6e-08,3.31801956396157e-05,14.6334163394265]
["rs6805924","3",69879670,"T","G",0.0109684,0.00200571,4.49997e-08,3.3250993736576e-05,14.6646413656405]
["rs684773","3",135956305,"C","A",0.0291133,0.00234718,2.49977e-35,0.000124761407958902,55.0283929893745]
["rs3103310","3",12473045,"G","A",0.0202549,0.00236652,1.10002e-17,6.09027950647664e-05,26.8606211495981]
["rs9831084","3",37025661,"C","T",-0.0118516,0.00199656,2.90001e-09,3.97172134602019e-05,17.5165428852104]
["rs9859117","3",127397553,"C","G",0.0147856,0.00247772,2.39999e-09,2.60941473771997e-05,11.5081846076735]
["rs11185542","3",196187927,"C","G",-0.0126395,0.00223848,1.6e-08,2.86361922615817e-05,12.6293233497808]
["rs6792725","3",24520283,"G","A",-0.0152543,0.00221886,6.20012e-12,4.56499877929738e-05,20.1332027969925]
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["rs3775228","4",87985166,"T","C",0.0338197,0.00203602,5.79963e-62,0.000300233905313871,132.447120634367]
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["rs373798","5",55794120,"ATTTTACAGAGAGCTGATTGGTCTG","A",0.0317126,0.00378401,5.30029e-17,2.42379874660128e-05,10.6895508975368]
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["rs6517522","21",40553845,"C","T",-0.0129031,0.00199242,9.3994e-11,4.75484075637698e-05,20.9705105277098]
["rs140288","22",24335977,"A","G",-0.0132623,0.00200841,4.00037e-11,4.85565588322203e-05,21.4151620834104]
["rs134551","22",28807625,"T","C",-0.0116536,0.00211111,3.40001e-08,3.08050489178544e-05,13.5858763570444]
["rs2267373","22",38600542,"T","C",0.0215638,0.00202145,1.39991e-26,0.000125654757491386,55.4224713174993]
["rs5755799","22",36012864,"G","C",0.0118859,0.00200343,2.99999e-09,3.95638958736666e-05,17.4489223221751]
["rs2071887","22",38879010,"A","T",0.016312,0.00209671,7.29962e-15,6.20093065982905e-05,27.3486682120907]
["rs4253750","22",46613852,"C","T",0.0177576,0.00243701,3.19963e-13,4.05636297711921e-05,17.8898542973389]

{"sheet":"Table S5","index":4,"n_rows":301,"n_cols":10,"rows_kept":301,"flags":["formulas_cached_only"]}
["Supplementary table S5: The characteristics of SNPs adopted as instrumental variables of Apolipoprotein A-I || id:ieu-b-107 "]
["SNP","Chr","Pos","EA","NEA","Beta","SE","P value","R2","F"]
["rs3768321",1,40035928,"T","G",-0.04228,0.002465,{"v":6.2e-66,"d":"6.20E-66"},0.000565,222.269]
["rs4660586",1,42407229,"T","C",0.012587,0.002236,{"v":1.8e-08,"d":"1.80E-08"},{"v":6.11e-05,"d":"6.11E-05"},24.01632]
["rs12740374",1,110000000,"T","G",0.044297,0.002359,{"v":1.1e-78,"d":"1.10E-78"},0.000675,265.7607]
["rs12045101",1,110000000,"T","C",-0.01488,0.002295,{"v":8.9e-11,"d":"8.90E-11"},{"v":8.1e-05,"d":"8.10E-05"},31.84281]
["rs10798615",1,179000000,"G","T",-0.01532,0.001964,{"v":6.2e-15,"d":"6.20E-15"},0.000117,45.93467]
["rs199717562",1,55491851,"G","A",0.015199,0.002618,{"v":6.4e-09,"d":"6.40E-09"},{"v":7.25e-05,"d":"7.25E-05"},28.5233]
["rs57274629",1,66110292,"G","A",0.015004,0.002061,{"v":3.3e-13,"d":"3.30E-13"},0.000103,40.67212]
["rs698927",1,93836218,"C","A",0.024554,0.002529,{"v":2.8e-22,"d":"2.80E-22"},0.000181,71.13034]
["rs140584594",1,110000000,"G","A",0.035674,0.002192,{"v":1.4e-59,"d":"1.40E-59"},0.000502,197.4852]
["rs2642438",1,221000000,"G","A",0.029129,0.002139,{"v":3.3e-42,"d":"3.30E-42"},0.000355,139.461]
["rs557933",1,235000000,"C","A",0.019042,0.001964,{"v":3.2e-22,"d":"3.20E-22"},0.000181,71.18171]
["rs72761606",1,244000000,"C","T",-0.01611,0.002901,{"v":2.8e-08,"d":"2.80E-08"},{"v":5.92e-05,"d":"5.92E-05"},23.28461]
["rs2999141",1,23832103,"C","A",-0.01213,0.002225,{"v":4.9e-08,"d":"4.90E-08"},{"v":5.88e-05,"d":"5.88E-05"},23.12476]
["rs1168124",1,63139730,"T","C",0.042611,0.002054,{"v":1.2e-95,"d":"1.20E-95"},0.000825,324.7894]
["rs9426827",1,155000000,"C","T",0.017073,0.001958,{"v":2.8e-18,"d":"2.80E-18"},0.000145,57.2021]
["rs3747973",1,206000000,"G","A",0.014847,0.001995,{"v":9.9e-14,"d":"9.90E-14"},0.000106,41.85692]
["rs2298214",1,935222,"A","C",-0.01315,0.001998,{"v":4.7e-11,"d":"4.70E-11"},{"v":8.44e-05,"d":"8.44E-05"},33.17502]
["rs472629",1,20917108,"A","G",-0.01827,0.002076,{"v":1.3e-18,"d":"1.30E-18"},0.000148,58.33323]
["rs75246752",1,146000000,"C","G",0.049676,0.008671,{"v":1e-08,"d":"1.00E-08"},{"v":6.27e-05,"d":"6.27E-05"},24.66466]
["rs1771591",1,162000000,"A","G",-0.01274,0.002042,{"v":4.5e-10,"d":"4.50E-10"},{"v":8.1e-05,"d":"8.10E-05"},31.86638]
["rs61805076",1,182000000,"C","T",-0.01535,0.002077,{"v":1.5e-13,"d":"1.50E-13"},0.000105,41.1747]
["rs12044156",1,220000000,"C","G",-0.01192,0.001972,{"v":1.5e-09,"d":"1.50E-09"},{"v":6.99e-05,"d":"6.99E-05"},27.47967]
["rs2281719",1,230000000,"T","C",0.053446,0.002012,"#######",0.001356,533.8882]
["rs10917383",1,23788994,"G","A",0.020392,0.002961,{"v":5.7e-12,"d":"5.70E-12"},{"v":9.08e-05,"d":"9.08E-05"},35.70721]
["rs34397747",1,27092322,"C","T",-0.03933,0.003559,{"v":2.2e-28,"d":"2.20E-28"},0.000239,93.93253]
["rs267738",1,151000000,"G","T",0.034376,0.002365,{"v":7.5e-48,"d":"7.50E-48"},0.000405,159.1637]
["rs10752898",1,183000000,"C","T",0.01254,0.001968,{"v":1.9e-10,"d":"1.90E-10"},{"v":7.76e-05,"d":"7.76E-05"},30.50482]
["rs76962725",1,224000000,"A","G",-0.02977,0.005235,{"v":1.3e-08,"d":"1.30E-08"},{"v":6.36e-05,"d":"6.36E-05"},25.00001]
["rs62135193",2,48755477,"T","C",-0.01083,0.001975,{"v":4.2e-08,"d":"4.20E-08"},{"v":5.82e-05,"d":"5.82E-05"},22.89725]
["rs1446585",2,136000000,"G","A",0.018595,0.002236,{"v":9.2e-17,"d":"9.20E-17"},0.000128,50.19256]
["rs72926946",2,203000000,"A","C",-0.01541,0.002142,{"v":6.2e-13,"d":"6.20E-13"},{"v":9.91e-05,"d":"9.91E-05"},38.9722]
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["rs17326656",2,48962291,"T","G",-0.01819,0.002306,{"v":3.1e-15,"d":"3.10E-15"},0.00012,47.28405]
["rs6705285",2,66709468,"T","G",0.011158,0.001977,{"v":1.7e-08,"d":"1.70E-08"},{"v":5.93e-05,"d":"5.93E-05"},23.31257]
["rs2943645",2,227000000,"T","C",-0.03387,0.002048,{"v":1.8e-61,"d":"1.80E-61"},0.000524,206.2455]
["rs10170658",2,239000000,"T","G",-0.01329,0.002358,{"v":1.7e-08,"d":"1.70E-08"},{"v":6.12e-05,"d":"6.12E-05"},24.05128]
["rs59104589",2,242000000,"T","C",0.017016,0.002041,{"v":7.6e-17,"d":"7.60E-17"},0.000133,52.35358]
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["rs1047891",2,212000000,"A","C",-0.02567,0.002105,{"v":3.3e-34,"d":"3.30E-34"},0.000285,111.9406]
["rs13402475",2,3639909,"G","C",-0.02401,0.002573,{"v":1e-20,"d":"1.00E-20"},0.000174,68.32239]
["rs35135293",2,20363666,"T","C",-0.0217,0.001967,{"v":2.7e-28,"d":"2.70E-28"},0.000235,92.46883]
["rs1260326",2,27730940,"C","T",-0.02581,0.002001,{"v":4.5e-38,"d":"4.50E-38"},0.000319,125.2753]
["rs4599108",2,85543222,"T","C",0.014046,0.001982,{"v":1.4e-12,"d":"1.40E-12"},{"v":9.86e-05,"d":"9.86E-05"},38.76796]
["rs11691486",2,101000000,"C","T",0.014133,0.002302,{"v":8.3e-10,"d":"8.30E-10"},{"v":7.29e-05,"d":"7.29E-05"},28.65536]
["rs13024140",2,112000000,"C","G",-0.01154,0.001987,{"v":6.3e-09,"d":"6.30E-09"},{"v":6.47e-05,"d":"6.47E-05"},25.44156]
["rs62114506",2,242793,"C","G",0.01405,0.002225,{"v":2.7e-10,"d":"2.70E-10"},{"v":7.64e-05,"d":"7.64E-05"},30.02533]
["rs676210",2,21231524,"A","G",0.060095,0.002423,"#######",0.001178,463.5342]
["rs113017476",2,31989359,"A","G",0.031294,0.005123,{"v":1e-09,"d":"1.00E-09"},{"v":7.28e-05,"d":"7.28E-05"},28.61997]
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["rs75265117",2,166000000,"G","C",0.03162,0.003019,{"v":1.2e-25,"d":"1.20E-25"},0.000211,83.00042]
["rs78058190",2,220000000,"A","G",-0.06623,0.005049,{"v":2.6e-39,"d":"2.60E-39"},0.00042,165.3026]
["rs13326165",3,52532118,"G","A",-0.01955,0.002427,{"v":8e-16,"d":"8.00E-16"},0.000124,48.89965]
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["rs9817452",3,157000000,"T","G",0.017489,0.002022,{"v":5.2e-18,"d":"5.20E-18"},0.000145,57.10594]
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["rs6765484",3,50041313,"T","C",0.020437,0.001965,{"v":2.5e-25,"d":"2.50E-25"},0.000208,81.88695]
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["rs79984435",16,56834234,"A","G",-0.08559,0.003372,"#######",0.001226,482.7383]
["rs9989419",16,56985139,"G","A",0.114993,0.001994,"#######",0.006317,2499.689]
["rs200561116",16,67972194,"A","AT",-0.05709,0.003103,{"v":1.4e-75,"d":"1.40E-75"},0.000659,259.2239]
["rs12943517",17,4083923,"A","G",-0.01186,0.002126,{"v":2.4e-08,"d":"2.40E-08"},{"v":6.03e-05,"d":"6.03E-05"},23.69694]
["rs3818716",17,16851834,"T","C",-0.01271,0.002046,{"v":5.2e-10,"d":"5.20E-10"},{"v":7.49e-05,"d":"7.49E-05"},29.45257]
["rs145947882",17,41809207,"C","A",-0.13643,0.006272,"#######",0.000945,372.0583]
["rs7216643",17,66827491,"T","C",-0.02236,0.002363,{"v":2.9e-21,"d":"2.90E-21"},0.000174,68.27382]
["rs78608249",17,7455707,"T","C",-0.01555,0.002171,{"v":8e-13,"d":"8.00E-13"},{"v":9.96e-05,"d":"9.96E-05"},39.15998]
["rs6505176",17,28661769,"G","T",-0.01744,0.002095,{"v":8.6e-17,"d":"8.60E-17"},0.000135,53.0135]
["rs7503353",17,8107979,"T","G",-0.01352,0.001972,{"v":7.3e-12,"d":"7.30E-12"},{"v":9.1e-05,"d":"9.10E-05"},35.76946]
["rs4795386",17,37746847,"G","A",0.025576,0.002208,{"v":5.1e-31,"d":"5.10E-31"},0.000262,102.9053]
["rs145773899",17,76386406,"C","T",0.030334,0.002054,{"v":2.3e-49,"d":"2.30E-49"},0.000457,179.6373]
["rs2071379",17,26695832,"G","A",-0.02143,0.001999,{"v":8.1e-27,"d":"8.10E-27"},0.000221,87.05785]
["rs34138141",17,40781561,"T","G",-0.01809,0.002186,{"v":1.3e-16,"d":"1.30E-16"},0.000132,51.96839]
["rs11870735",17,481604,"T","C",-0.01524,0.002549,{"v":2.2e-09,"d":"2.20E-09"},{"v":6.89e-05,"d":"6.89E-05"},27.07355]
["rs3760230",17,1994071,"G","C",-0.01363,0.001989,{"v":7.3e-12,"d":"7.30E-12"},{"v":9.05e-05,"d":"9.05E-05"},35.5873]
["rs2298624",18,47429022,"T","C",0.031959,0.00289,{"v":2e-28,"d":"2.00E-28"},0.000235,92.32661]
["rs8098618",18,21069269,"T","C",0.011536,0.001974,{"v":5.1e-09,"d":"5.10E-09"},{"v":6.64e-05,"d":"6.64E-05"},26.12108]
["rs78965095",18,46617871,"T","C",0.043694,0.006961,{"v":3.5e-10,"d":"3.50E-10"},{"v":7.59e-05,"d":"7.59E-05"},29.83239]
["rs77960347",18,47109955,"G","A",0.335992,0.008556,"#######",0.002961,1167.599]
["rs4632228",18,19641009,"T","G",-0.01986,0.002408,{"v":1.6e-16,"d":"1.60E-16"},0.000131,51.37225]
["rs150237291",18,46781014,"C","T",0.049471,0.006748,{"v":2.3e-13,"d":"2.30E-13"},0.000104,41.06732]
["rs681869",18,2981398,"T","C",-0.01653,0.00215,{"v":1.5e-14,"d":"1.50E-14"},0.000114,44.78439]
["rs8086351",18,47171888,"G","C",0.096182,0.002577,"#######",0.002683,1057.674]
["rs7238484",18,57735552,"T","G",-0.02137,0.002216,{"v":5.3e-22,"d":"5.30E-22"},0.000179,70.49452]
["rs76213248",19,11269893,"T","C",0.021302,0.002001,{"v":1.8e-26,"d":"1.80E-26"},0.00022,86.36269]
["rs429358",19,45411941,"C","T",-0.10254,0.002715,"#######",0.002747,1082.923]
["rs12462109",19,52343496,"T","C",-0.01341,0.00217,{"v":6.4e-10,"d":"6.40E-10"},{"v":7.36e-05,"d":"7.36E-05"},28.94247]
["rs4807462",19,3408665,"T","A",-0.01146,0.002056,{"v":2.5e-08,"d":"2.50E-08"},{"v":6.04e-05,"d":"6.04E-05"},23.76579]
["rs367070",19,54800500,"G","A",0.039058,0.002355,{"v":8.4e-62,"d":"8.40E-62"},0.000533,209.5552]
["rs10404380",19,8466254,"A","C",-0.02579,0.002015,{"v":1.6e-37,"d":"1.60E-37"},0.000318,125.0594]
["rs2965169",19,45251156,"C","A",0.018837,0.002012,{"v":7.6e-21,"d":"7.60E-21"},0.000169,66.31548]
["rs144311893",19,45423944,"T","C",0.122697,0.006902,{"v":1.1e-70,"d":"1.10E-70"},0.000647,254.7378]
["rs12977604",19,45442528,"G","C",0.037394,0.002093,{"v":2e-71,"d":"2.00E-71"},0.000699,275.086]
["rs737338",19,11347657,"T","C",-0.10808,0.005332,{"v":2.3e-91,"d":"2.30E-91"},0.000791,311.4246]
["rs7251640",19,18614935,"C","T",0.015159,0.002499,{"v":1.3e-09,"d":"1.30E-09"},{"v":7.19e-05,"d":"7.19E-05"},28.25725]
["rs8103728",19,33900257,"G","C",0.022849,0.002088,{"v":7.3e-28,"d":"7.30E-28"},0.000231,90.85284]
["rs2424993",20,33104592,"C","G",-0.01614,0.002142,{"v":4.9e-14,"d":"4.90E-14"},0.00011,43.17648]
["rs6062510",20,62372148,"C","G",-0.01524,0.002096,{"v":3.5e-13,"d":"3.50E-13"},0.000102,40.11897]
["rs11481448",20,22146056,"A","AT",0.011467,0.001971,{"v":5.9e-09,"d":"5.90E-09"},{"v":6.57e-05,"d":"6.57E-05"},25.85086]
["rs201877296",20,42819289,"A","T",-0.05786,0.005528,{"v":1.2e-25,"d":"1.20E-25"},0.000241,94.77459]
["rs1800961",20,43042364,"T","C",-0.149,0.005662,"#######",0.001336,526.1603]
["rs144033177",20,571467,"C","A",-0.04942,0.008064,{"v":8.9e-10,"d":"8.90E-10"},{"v":7.61e-05,"d":"7.61E-05"},29.91882]
["rs1132274",20,17596155,"A","C",-0.02877,0.002716,{"v":3.2e-26,"d":"3.20E-26"},0.000216,84.87155]
["rs6057911",20,30061695,"G","C",0.018581,0.002921,{"v":2e-10,"d":"2.00E-10"},{"v":7.88e-05,"d":"7.88E-05"},30.96741]
["rs2256720",20,46279531,"C","T",0.012175,0.001977,{"v":7.4e-10,"d":"7.40E-10"},{"v":7.32e-05,"d":"7.32E-05"},28.78499]
["rs4239651",20,46340596,"C","T",0.026423,0.002428,{"v":1.4e-27,"d":"1.40E-27"},0.000228,89.69366]
["rs9977268",21,46907287,"T","C",-0.01823,0.002467,{"v":1.5e-13,"d":"1.50E-13"},0.000106,41.61838]
["rs235314",21,46271452,"T","C",-0.02148,0.001975,{"v":1.5e-27,"d":"1.50E-27"},0.00023,90.30865]
["rs133015",22,38572526,"G","C",0.020034,0.001984,{"v":5.6e-24,"d":"5.60E-24"},0.000198,77.78805]
["rs11089620",22,21922456,"G","C",-0.03216,0.002513,{"v":1.7e-37,"d":"1.70E-37"},0.000317,124.5271]
["rs4820346",22,39125074,"G","C",0.013017,0.002138,{"v":1.1e-09,"d":"1.10E-09"},{"v":7.21e-05,"d":"7.21E-05"},28.35463]
["rs2294915",22,44340904,"T","C",-0.01999,0.002331,{"v":1e-17,"d":"1.00E-17"},0.000142,55.93663]
["rs9608972",22,30931307,"C","T",-0.0175,0.0023,{"v":2.8e-14,"d":"2.80E-14"},0.000112,44.09177]

{"sheet":"Table S6","index":5,"n_rows":151,"n_cols":10,"rows_kept":151,"flags":["formulas_cached_only"]}
["Supplementary table S6: The characteristics of SNPs adopted as instrumental variables of apolipoprotein B"]
["SNP","Chr","Pos","EA","NEA","Beta","SE","P value","R2","F"]
["rs34596921","1",25773708,"T","TA",0.0292255,0.00212054,3.29989e-43,0.00021071290895749,92.5671432610674]
["rs472495","1",55521313,"T","G",0.0407634,0.00217172,1.29987e-78,0.000365450009939595,160.56870960211]
["rs1556562","1",93034023,"T","G",0.0159957,0.00247804,1.09999e-10,3.14747834709378e-05,13.8245377221689]
["rs6657811","1",109807283,"T","A",-0.127721,0.00308568,1e-200,0.000881988757041065,387.722012413326]
["rs5776986","1",110106663,"G","GT",-0.0201193,0.00273998,2.09991e-13,3.77090199851892e-05,16.5628786556571]
["rs57754494","1",110241316,"A","G",0.0264394,0.00351614,5.50047e-14,2.6314238182961e-05,11.5578333163934]
["rs6667939","1",198994619,"T","C",0.0141028,0.00231955,1.2e-09,3.40287678212966e-05,14.9463517782618]
["rs556107","1",234853059,"T","C",0.0358479,0.00207937,1.29987e-66,0.000337612329111664,148.333465500565]
["rs11591147","1",55505647,"T","G",-0.345954,0.00790085,1e-200,0.000149706921740292,65.7629216759657]
["rs12046278","1",10799577,"C","T",-0.0156231,0.00217266,6.4003e-13,5.32131177268479e-05,23.3730836176945]
["rs12078100","1",16512586,"G","C",0.0152136,0.00213952,1.20005e-12,5.40720820913172e-05,23.7503915526133]
["rs76186504","1",109840169,"T","C",-0.11643,0.0066216,3.29989e-69,3.43472109930893e-05,15.0862254044638]
["rs144926613","1",182125704,"T","TTGGAGGGCAGACTAGCCCAGGCCC",-0.0145634,0.00220815,4.19952e-11,4.36720437923336e-05,19.1821234206525]
["rs2807854","1",221029841,"C","T",0.0162948,0.00220437,1.39991e-13,5.49005035381539e-05,24.1142838463253]
["rs6426328","1",246891260,"T","G",0.0122017,0.00207321,4e-09,3.94154586087643e-05,17.3124247836351]
["rs10127775","1",230295789,"T","A",-0.0233243,0.00212188,4.19952e-28,0.000131348442484367,57.6973905828325]
["rs478975","1",234773373,"A","G",0.0141364,0.00217403,7.89951e-11,4.42185303091673e-05,19.4221679538723]
["rs1260326","2",27730940,"C","T",-0.0495555,0.00211469,1.90108e-121,0.000597829611913821,262.731007884374]
["rs11901691","2",43850522,"A","C",0.0142576,0.00211213,1.50003e-11,5.06408836961856e-05,22.2432102257911]
["rs13389219","2",165528876,"T","C",-0.0161286,0.00211805,2.60016e-14,6.29634452141058e-05,27.6560420190643]
["rs7603427","2",204317553,"T","C",0.0135724,0.00207851,6.59933e-11,4.83232311315338e-05,21.2251686604742]
["rs148150904","2",109064447,"TTAAAG","T",0.0159241,0.00263918,1.6e-09,2.54787069159361e-05,11.1908389500679]
["rs75331444","2",44069772,"A","G",-0.0903607,0.00418412,1.99986e-103,0.000130192056323818,57.1893590423505]
["rs150474434","2",118845121,"A","G",-0.0343097,0.00345194,2.80027e-23,4.0988474473087e-05,18.0033677808542]
["rs374929797","2",242396694,"C","T",-0.0121985,0.00211702,8.30004e-09,3.73063277450749e-05,16.3859981229862]
["rs7590687","2",44077225,"C","T",-0.0430516,0.00398578,3.40017e-27,3.77269468075594e-05,16.5707529251559]
["rs12471768","2",64928603,"C","T",0.0139101,0.00226938,8.79995e-10,3.56475249172475e-05,15.6573788607572]
["rs17050272","2",121306440,"A","G",-0.0244302,0.00210465,3.80014e-31,0.000148335048101772,65.1601986880821]
["rs12469941","2",135629927,"T","C",0.0134202,0.00209668,1.5e-10,4.48088714432163e-05,19.6814759490435]
["rs2287622","2",169830328,"G","A",-0.0203449,0.00211842,7.70016e-22,0.000100561700671244,44.1723477216278]
["rs1250258","2",216300185,"T","C",0.0141509,0.00235577,1.89998e-09,3.18679580991604e-05,13.9972356759685]
["rs62122481","2",21216815,"A","C",0.0841137,0.00214492,1e-200,0.00164456755512487,723.503655659617]
["rs4671050","2",62988169,"T","G",-0.0196981,0.00222973,1e-18,7.68321729244437e-05,33.7482052824349]
["rs7569317","2",203527979,"C","T",0.0180783,0.0020715,2.60016e-18,8.63787242391938e-05,37.9418495991084]
["rs5849920","3",69820400,"G","GT",-0.0146084,0.00224287,7.39946e-11,4.471232066558e-05,19.6390658923825]
["rs12054451","3",122064369,"G","T",0.0159506,0.00238162,2.09991e-11,3.92484125164725e-05,17.239050363545]
["rs13076933","3",12327431,"G","T",-0.0182624,0.00238248,1.80011e-14,5.14032739079688e-05,22.5780953276852]
["rs9834932","3",32535382,"G","A",-0.0317059,0.00365151,3.90032e-18,2.77947506122925e-05,12.2081273277807]
["rs71637095","3",135980425,"G","T",0.0152202,0.0021958,4.19952e-12,4.91987694930311e-05,21.6097531198357]
["rs11709868","3",142648844,"T","G",-0.015551,0.00228244,9.49948e-12,4.41380408441565e-05,19.3868128911829]
["rs13108218","4",3443931,"G","A",-0.0229367,0.00215262,1.59993e-26,0.000122427913554983,53.7783927447292]
["rs2137234","4",26080549,"C","T",0.0152817,0.00262327,5.69994e-09,2.42837314068202e-05,10.6659652480876]
["rs9884390","4",69373407,"C","T",0.023248,0.00248318,7.8001e-21,7.15568438531965e-05,31.4308735965643]
["rs4689088","4",7222253,"A","G",0.0124572,0.00214057,5.89997e-09,3.63822655432471e-05,15.9801090063499]
["rs278981","4",40428010,"C","T",0.0148256,0.00239561,6.1e-10,3.1977621035559e-05,14.0454040288773]
["rs11099097","4",81167309,"T","C",-0.0161746,0.00229432,1.80011e-12,4.67320722760372e-05,20.5262461625221]
["rs116734477","5",52095024,"T","C",-0.0633493,0.00526644,2.49977e-33,2.57937907074064e-05,11.3292346280883]
["rs7707394","5",74472939,"A","G",0.0352503,0.00216546,1.39991e-59,0.000277099033953456,121.738954647493]
["rs6874202","5",156391628,"C","T",0.0312135,0.00215543,1.59993e-47,0.000221527827784985,97.319239216764]
["rs12916","5",74656539,"C","T",0.0549288,0.00212005,5.19996e-148,0.000733919022543443,322.582791376287]
["rs7734476","5",122848876,"A","G",0.019942,0.00208686,1.20005e-21,0.000102915228562359,45.2062557794766]
["rs28590710","5",71932487,"A","G",-0.0177486,0.00273845,9.09913e-11,3.02352007359637e-05,13.2800645110604]
["rs1003533","5",131755651,"T","C",-0.0200281,0.00266165,5.30029e-14,3.94116954659172e-05,17.3107718358443]
["rs7746081","6",16126934,"A","G",-0.0227685,0.00225861,6.70039e-24,9.79344710252238e-05,43.0182078533612]
["rs3823376","6",29944184,"T","C",0.0164137,0.00207374,2.49977e-15,7.13164815703181e-05,31.3252885128235]
["rs9496567","6",100602753,"A","G",-0.0190492,0.00242335,3.80014e-15,5.18381416614309e-05,22.769114183967]
["rs3127580","6",160710851,"T","C",0.0404476,0.00286539,2.99985e-45,0.000118918844038053,52.2367952669508]
["rs79220007","6",26098474,"C","T",-0.0537922,0.00390806,4.19952e-43,6.06524278364983e-05,26.6408899695805]
["rs6940814","6",42924932,"G","A",-0.0199476,0.00210823,2.99985e-21,9.87965871468483e-05,43.3969341029235]
["rs1358980","6",43764551,"T","C",0.0149035,0.00209447,1.10002e-12,5.7574265339107e-05,25.2887642101406]
["rs4052908","6",139842576,"AATT","A",-0.012576,0.00217168,7.00003e-09,3.53444689873003e-05,15.5242636097038]
["rs72848251","6",32601288,"A","G",0.0348659,0.0026847,1.50003e-38,0.000120784620772247,53.0564632634149]
["rs3822855","6",116316882,"T","G",0.0148392,0.00211668,2.39994e-12,5.37851611985799e-05,23.6243588603002]
["rs4935356","6",32412388,"A","T",0.0245813,0.00255516,6.59933e-22,7.77204380497863e-05,34.1384022883029]
["rs118039278","6",160985526,"A","G",0.0868026,0.00387054,2.19786e-111,0.000166066584037752,72.9505511572235]
["rs9482772","6",127446790,"C","T",0.0177235,0.00208937,2.19989e-17,8.10313119532132e-05,35.5928087175811]
["rs12208357","6",160543148,"T","C",0.0629791,0.0040818,1e-53,7.06452489216457e-05,31.030433222053]
["rs28406917","7",21449451,"T","C",0.0134005,0.00210735,2e-10,4.50663466475844e-05,19.7945723128364]
["rs13247874","7",73010442,"T","C",-0.0215939,0.00261336,1.39991e-16,4.92102253918349e-05,21.6147851832492]
["rs10953298","7",100216773,"T","C",-0.0170824,0.00245825,3.69999e-12,3.96759759380561e-05,17.4268561712316]
["rs4470903","7",21604916,"G","C",0.0345326,0.00253303,2.60016e-42,0.000142833811797836,62.7432860100567]
["rs112758337","7",97977268,"A","G",-0.0212571,0.00267849,2.09991e-15,4.3342905758105e-05,19.0375494665412]
["rs2073547","7",44582331,"G","A",0.0312042,0.00266416,1.10002e-31,9.37737679674994e-05,41.1904267580627]
["rs45537841","7",87110640,"T","C",-0.0158986,0.00270418,4.09996e-09,2.33032496162856e-05,10.2353053863444]
["rs13230111","7",130437124,"G","A",-0.0138317,0.00207813,2.80027e-11,5.04194176061377e-05,22.1459298305114]
["rs7012637","8",9173209,"A","G",0.0200133,0.00209504,1.29987e-21,0.00010359846362987,45.5064028012178]
["rs13702","8",19824492,"C","T",-0.0295019,0.00229451,7.8001e-38,0.000154335708302957,67.7965585450419]
["rs59328596","8",21928227,"A","G",-0.0210021,0.00292183,6.59933e-13,2.96840219607057e-05,13.0379656726648]
["rs10087526","8",55433151,"G","T",0.0187619,0.00260759,6.20012e-13,3.75428313954662e-05,16.4898811396929]
["rs9297994","8",59392324,"A","G",-0.0291083,0.00220081,6.20012e-40,0.000177577312537182,78.0079390342511]
["rs2737263","8",116667539,"T","G",-0.0185263,0.00231348,1.20005e-15,5.8901972745395e-05,25.8719771639442]
["rs3860846","8",126631687,"T","C",0.0138403,0.00235387,4.09996e-09,3.14081529445708e-05,13.7952709550709]
["rs28814720","8",141988687,"G","A",0.0117382,0.00214286,4.30002e-08,3.41060034029305e-05,14.9802768839823]
["rs55831924","8",145031968,"T","C",0.0182553,0.00217539,4.79954e-17,7.40025907082945e-05,32.5052313415023]
["rs28601761","8",126500031,"G","C",-0.07256,0.00212854,1e-200,0.00128803950180609,566.45201824263]
["rs581080","9",15305378,"C","G",0.0185579,0.00270151,6.4003e-12,3.18548637274099e-05,13.9914841042626]
["rs6560499","9",78730766,"A","G",-0.0121606,0.00211507,8.99995e-09,3.67631922875423e-05,16.1474288420275]
["rs2519093","9",136141870,"T","C",0.0410869,0.00267778,3.90032e-53,0.000161327879451638,70.8685736664221]
["rs10448340","9",139320069,"G","T",-0.0170557,0.00223016,1.99986e-14,5.79310624130835e-05,25.4454918689528]
["rs6475606","9",22081850,"T","C",-0.017332,0.00207721,7.19946e-17,7.91792468571662e-05,34.7792291638012]
["rs2761311","10",95052021,"T","C",0.012077,0.00211012,1e-08,3.65193013118391e-05,16.0403011483662]
["rs10794579","10",124686656,"C","T",0.0137267,0.00210335,6.79986e-11,4.73929987728088e-05,20.8165603362214]
["rs2068888","10",94839642,"A","G",-0.0241729,0.00208746,5.19996e-31,0.000151178295019601,66.4093609661131]
["rs72823013","10",115786233,"A","G",-0.0228563,0.00313773,3.19963e-13,2.66434959912881e-05,11.7024549556373]
["rs174564","11",61588305,"G","A",-0.0450573,0.00218206,1e-94,0.000440832078915485,193.704130038967]
["rs964184","11",116648917,"C","G",-0.0765255,0.00305668,2.50035e-138,0.000329588554066016,144.806974729863]
["rs11601507","11",5701074,"A","C",0.0414121,0.004036,1.10002e-24,3.09776544660015e-05,13.606179060835]
["rs546240","11",30533622,"T","C",-0.0118734,0.00214585,3.09999e-08,3.28469599431662e-05,14.4272528619548]
["rs10832963","11",18664241,"G","T",0.0219536,0.00238777,3.80014e-20,7.32776700566464e-05,32.1867905939411]
["rs77498041","11",66183801,"A","G",-0.0162677,0.00265126,8.50002e-10,2.65017388512888e-05,11.6401902096334]
["rs4307732","11",126244955,"A","G",0.0481874,0.00338596,5.79963e-46,8.73200367456396e-05,38.3553571703233]
["rs11047939","12",9061971,"A","G",0.0152893,0.00250351,1e-09,2.96003377394532e-05,13.0012083793798]
["rs11065384","12",121423285,"C","T",-0.0216973,0.00224856,4.90004e-22,9.0625948668542e-05,39.8076117691885]
["rs2160994","12",50650057,"C","T",0.0172687,0.00217691,2.09991e-15,6.54080042143349e-05,28.7298595097584]
["rs35882350","12",623129,"G","A",0.0135528,0.0023664,1e-08,2.88124173516831e-05,12.6551240745839]
["rs11057397","12",124419728,"T","C",-0.0183422,0.00220085,7.8001e-17,7.06779297383036e-05,31.0447890576395]
["rs597808","12",111973358,"G","A",0.0216847,0.00208463,2.39994e-25,0.000123056112289695,54.0543729119645]
["rs2238162","13",32959199,"T","C",-0.0226439,0.00208185,1.50003e-27,0.000134393330262092,59.0350972944018]
["rs6602909","13",114551993,"C","T",0.021441,0.0022203,4.60045e-22,9.35339032963298e-05,41.0850555802032]
["rs11621792","14",24871926,"T","C",0.0210752,0.00210348,1.29987e-23,0.000113263588462367,49.7523623468272]
["rs8016418","14",70798289,"A","T",0.0197194,0.00214984,4.60045e-20,8.97757595472428e-05,39.434131131338]
["rs13379043","14",74250126,"C","T",-0.0143675,0.00235876,1.09999e-09,3.40947004241258e-05,14.9753121414624]
["rs35980001","15",58722590,"G","GC",-0.0244043,0.00255807,1.39991e-21,6.95856604215587e-05,30.5649839696689]
["rs2043085","15",58680954,"C","T",-0.0193562,0.00213525,1.20005e-19,8.88334114050141e-05,39.0201665845303]
["rs71140104","15",75157721,"C","CA",-0.0128734,0.00212438,1.40001e-09,4.11925167477286e-05,18.092992961719]
["rs183130","16",56991363,"T","C",-0.0478017,0.00222241,1.30017e-102,0.000461340632268184,202.719864690323]
["rs4782568","16",83980529,"G","C",-0.0182854,0.00210073,3.19963e-18,8.54168282698632e-05,37.5193007577328]
["rs12597418","16",71855220,"A","G",0.0182198,0.00215637,2.90001e-17,7.56139186986153e-05,33.2130518284569]
["rs34042070","16",72101525,"G","C",0.0494204,0.00267088,1.9002e-76,0.00023790358016342,104.514971736693]
["rs1561139","16",56852822,"T","G",-0.0131421,0.0021042,4.20001e-10,4.33898085991165e-05,19.0581515439829]
["rs55714927","17",7080316,"T","C",-0.0321831,0.00264686,5.10035e-34,0.000103747320056266,45.5717958882462]
["rs12603290","17",45650196,"C","T",-0.0288448,0.00207989,9.79941e-44,0.000218761747011472,96.1038082653932]
["rs77542162","17",67081278,"G","A",0.115967,0.00701839,2.49977e-61,2.73228658511314e-05,12.0008584540528]
["rs35278712","17",29618023,"GAAAT","G",0.0199983,0.00230836,4.60045e-18,7.00547111994805e-05,30.7710254706489]
["rs72631343","17",67191270,"G","C",-0.0278921,0.00310009,2.29985e-19,4.13868847346489e-05,18.1783687641273]
["rs2199048","17",73868288,"G","A",-0.0132194,0.00224306,3.79997e-09,3.40538428149344e-05,14.9573657662157]
["rs62119267","19",45134682,"C","A",-0.33464,0.00708026,1e-200,0.000221935089405459,97.4981927580772]
["rs200046586","19",45241248,"C","CA",0.412271,0.00778939,1e-200,0.000234726213205299,103.118774233712]
["rs148933445","19",45302504,"A","G",-0.573249,0.00759178,1e-200,0.000547617169392341,240.651817270131]
["rs12691088","19",45418486,"A","G",0.246111,0.00769582,1e-200,9.53416615028248e-05,41.8791946639803]
["rs143020224","19",11187324,"G","C",-0.165274,0.0031786,1e-200,0.0012866209438037,565.827363306118]
["rs2738447","19",11227480,"C","A",0.0436273,0.00209036,9.8992e-97,0.00047882372027364,210.405871150818]
["rs7249565","19",11302807,"A","G",0.0145524,0.00208362,2.90001e-12,5.3922713991144e-05,23.6847802051073]
["rs8107974","19",19388500,"T","A",-0.0908575,0.00388309,4.4978e-121,0.000174553841706031,76.6795266293425]
["rs148601586","19",45346666,"G","C",0.183504,0.00917667,5.90065e-89,2.39111935377453e-05,10.5023342594473]
["rs138692741","19",45467132,"T","C",0.0714986,0.00568647,2.99985e-36,2.48365661672374e-05,10.9087888363004]
["rs454715","19",49114236,"G","T",-0.0235286,0.0020918,2.39994e-29,0.000140088449533999,61.5371487404824]
["rs35081008","19",58662235,"T","C",-0.0311143,0.00290126,7.8001e-27,6.60904538296642e-05,29.0296389894498]
["rs2618566","20",17844684,"T","G",-0.0303008,0.00219303,1.99986e-43,0.000195099881913444,85.7069307470353]
["rs6073958","20",44551855,"C","T",0.0423193,0.00260555,2.49977e-59,0.000191218366811973,84.0014639469659]
["rs3746337","20",25208272,"T","C",0.0156368,0.00207666,5.10035e-14,6.45140574926816e-05,28.3371763657009]
["rs969075","20",17792323,"C","T",0.0138101,0.00221388,4.39997e-10,3.94777794077108e-05,17.3397989859788]
["rs6072279","20",39755154,"A","G",0.0292319,0.00208189,8.69961e-45,0.000223813492249507,98.3235777011864]
["rs17569873","20",62896110,"T","C",0.0183445,0.00259488,1.59993e-12,3.65881734666126e-05,16.0705528367927]
["rs224391","20",34107160,"C","G",-0.0174615,0.00248326,1.99986e-12,3.95677764886144e-05,17.3793299085587]
["rs6129620","20",39144286,"A","T",-0.0253099,0.00223276,8.69961e-30,0.000130981689589825,57.5362660454657]
["rs1888488","21",40686521,"T","C",0.0173586,0.00210255,1.50003e-16,7.62713988735473e-05,33.5018688764526]
["rs138354","22",41272143,"C","T",-0.0120708,0.00208392,6.90001e-09,3.80118860492846e-05,16.6959111385501]
["rs9616822","22",50840573,"A","G",0.0159299,0.00218001,2.70023e-13,5.54150918037274e-05,24.3403221224837]

{"sheet":"Table S7","index":6,"n_rows":12,"n_cols":10,"rows_kept":12,"flags":["formulas_cached_only"]}
["Supplementary table S7: The characteristics of SNPs adopted as instrumental variables of circulating leptin levels ebi-a-GCST90007310"]
["SNP","Chr","Pos","EA","NEA","Beta","SE","P value","R2","F"]
["rs780094",2,27741237,"C","T",0.039157,0.00738,{"v":1.12e-07,"d":"1.12E-07"},0.000757,37.81851]
["rs713586",2,25158008,"C","T",0.031133,0.006606,{"v":2.45e-06,"d":"2.45E-06"},0.000482,24.08879]
["rs10195252",2,166000000,"C","T",0.054764,0.007223,{"v":3.4e-14,"d":"3.40E-14"},0.001416,70.78147]
["rs900399",3,157000000,"G","A",-0.03305,0.00701,{"v":2.43e-06,"d":"2.43E-06"},0.000522,26.08971]
["rs10938397",4,45182527,"G","A",0.031978,0.006671,{"v":1.64e-06,"d":"1.64E-06"},0.000504,25.14969]
["rs675209",6,7102084,"C","T",0.035898,0.007204,{"v":6.25e-07,"d":"6.25E-07"},0.000516,25.77128]
["rs1167827",7,75163169,"G","A",0.033838,0.007402,{"v":4.84e-06,"d":"4.84E-06"},0.000568,28.34731]
["rs972283",7,130000000,"G","A",-0.04137,0.006415,{"v":1.12e-10,"d":"1.12E-10"},0.000854,42.67247]
["rs62621812",7,127000000,"A","G",-0.09769,0.018216,{"v":8.18e-08,"d":"8.18E-08"},0.000581,29.01637]
["rs1121980",16,53809247,"A","G",0.054863,0.006582,{"v":7.71e-17,"d":"7.71E-17"},0.001477,73.81601]

{"sheet":"Table S8","index":7,"n_rows":29,"n_cols":10,"rows_kept":29,"flags":["formulas_cached_only"]}
["Supplementary table S8: The characteristics of SNPs adopted as instrumental variables of Atherosclerosis, excluding cerebral, coronary and PAD finn-b-I9_ATHSCLE"]
["SNP","Chr","Pos","EA","NEA","Beta","SE","P value","R2","F"]
["rs115727599","1",229176589,"T","G",0.3625,0.0784,3.77503e-06,3.05540087455676e-06,26.5126816807863]
["rs1012570","2",59691884,"T","C",-0.1141,0.0248,4.01597e-06,2.95451579072265e-05,25.6499450227286]
["rs17020710","3",28017987,"A","G",0.387,0.0835,3.59402e-06,2.69615202935787e-06,26.5382535226852]
["rs13115229","4",108825053,"G","T",0.451,0.0982,4.38601e-06,2.01566556050145e-06,27.4445352505238]
["rs13179238","5",159136348,"A","G",0.1425,0.0286,6.30899e-07,2.73555945684658e-05,31.6130101755997]
["rs117913648","6",69960612,"T","C",0.4194,0.0872,1.521e-06,2.64340590425997e-06,28.3839503398821]
["rs118039278","6",160985526,"A","G",0.2278,0.0458,6.71707e-07,1.01406506414109e-05,30.045656724496]
["rs1980496","6",32340070,"T","C",0.1266,0.022,9.19009e-09,6.49034289480627e-05,44.4674281499126]
["rs117733303","6",160922870,"G","A",0.4339,0.092,2.399e-06,2.32782913055356e-06,27.8205578515763]
["rs2596546","6",31329386,"G","A",0.1133,0.0209,5.53898e-08,6.26525421367408e-05,38.7064549306083]
["rs143447746","7",52431950,"T","C",0.6649,0.1214,4.26403e-08,1.93877160060079e-06,40.4229942604862]
["rs2107595","7",19049388,"A","G",0.1242,0.0241,2.65901e-07,3.89987448159381e-05,32.0035331444477]
["rs12543983","8",131477594,"T","A",-0.1287,0.028,4.18004e-06,2.35395627603192e-05,26.0517898915057]
["rs28601761","8",126500031,"G","C",-0.0917,0.0195,2.45799e-06,5.02809539101393e-05,26.9933995798093]
["rs7002081","8",24297795,"G","T",-0.1205,0.0244,7.72805e-07,3.584059356449e-05,30.1401885788445]
["rs117972249","8",110877178,"T","G",0.7997,0.1479,6.39897e-08,1.3197298937633e-06,40.8425936176467]
["rs7872477","9",27069285,"G","T",-0.1074,0.0225,1.87802e-06,3.88858071894321e-05,27.7967277338095]
["rs9632884","9",22072301,"C","G",0.1542,0.0192,1.10892e-15,0.000148769841043446,78.0252612414574]
["rs117772502","13",98393867,"A","G",-0.2006,0.0415,1.36499e-06,1.19786974111786e-05,29.1360785956022]
["rs191113889","15",69459332,"G","A",0.4024,0.0807,6.05703e-07,3.37924536210276e-06,31.0899591569024]
["rs146009840","15",78906177,"T","A",0.1093,0.0204,8.02398e-08,5.97029768973158e-05,35.1215569642961]
["rs7199607","16",12711091,"G","C",0.2271,0.0488,3.30301e-06,7.93056450100671e-06,26.6628719501785]
["rs7198696","16",81541175,"A","G",-0.0935,0.0202,3.81804e-06,4.50362025428329e-05,25.9406184049245]
["rs4783580","16",69552512,"T","C",-0.1354,0.0278,1.083e-06,2.72154660501447e-05,29.7076391217118]
["rs145947882","17",41809207,"C","A",0.3107,0.0574,6.16297e-08,7.98757046883528e-06,37.21284290912]
["rs3752075","18",74637067,"C","T",0.1,0.0197,3.86198e-07,5.74515193354012e-05,31.5002651969813]
["rs11699116","20",23736452,"G","A",-0.1636,0.0355,4.07596e-06,1.47510366051023e-05,26.2430859654214]

{"sheet":"Table S9","index":8,"n_rows":140,"n_cols":10,"rows_kept":140,"flags":["formulas_cached_only"]}
["Supplementary table S9: The characteristics of SNPs adopted as instrumental variables of Body mass index ebi-a-GCST006368"]
["SNP","Chr","Pos","EA","NEA","Beta","SE","P value","R2","F"]
["rs201468966","1",39976059,"CA","C",0.032,0.00538,2.90001e-09,5.39347296074253e-05,17.0089646819646]
["rs3127553","1",49438005,"A","G",-0.0213,0.0026,2.90001e-16,9.96551479507603e-05,31.4288846806853]
["rs11165643","1",96924097,"T","C",0.0186,0.00254,2.60016e-13,8.29225612289504e-05,26.151383610452]
["rs1074657","1",243746634,"C","T",-0.0172,0.00297,7.69999e-09,5.16258604276498e-05,16.2807974667349]
["rs10909880","1",2727804,"T","C",-0.0151,0.00264,1e-08,5.15443094550962e-05,16.2550781218943]
["rs3101336","1",72751185,"C","T",0.032,0.00256,7.39946e-36,0.000225505514560151,71.1280762624081]
["rs10920678","1",190239907,"G","A",-0.0165,0.00253,6.79986e-11,6.48053490306112e-05,20.4373672407754]
["rs2820311","1",201841476,"G","A",0.0282,0.00306,2.60016e-20,0.000110860211977396,34.9630895615322]
["rs543874","1",177889480,"G","A",0.0482,0.00317,4.19952e-52,0.000270325626549142,85.2688850689204]
["rs4130548","1",78463868,"C","T",0.0222,0.00271,2.39994e-16,0.000101317216160594,31.9531149308148]
["rs4926726","1",47679486,"A","G",-0.016,0.0028,1e-08,5.14662597463902e-05,16.23046300095]
["rs2481665","1",62594677,"C","T",-0.0182,0.00257,1.39991e-12,7.62462588816793e-05,24.0457099024654]
["rs197374","1",112289983,"T","C",0.0163,0.00288,1.6e-08,5.01746693635268e-05,15.8231250305081]
["rs6676190","1",151079317,"T","C",-0.0152,0.00274,2.69998e-08,4.36275328230772e-05,13.7583245798505]
["rs13021737","2",632348,"G","A",0.0578,0.00329,3.80014e-69,0.00023186516616939,73.1344781636183]
["rs1396141","2",41673745,"T","C",0.0168,0.00295,1.2e-08,4.842620224734e-05,15.2717002981347]
["rs972540","2",207244783,"G","A",0.0179,0.0028,1.7e-10,5.2277073127348e-05,16.4861754743444]
["rs4671328","2",58935282,"G","T",-0.0243,0.00281,4.90004e-18,0.00011745149720769,37.0420930362457]
["rs6545714","2",59307725,"A","G",-0.0179,0.00254,1.69981e-12,7.39481024514218e-05,23.3208889030255]
["rs144839874","2",194880111,"G","A",-0.139,0.0249,2e-08,4.00859226603396e-05,12.6414020235886]
["rs17203016","2",208255518,"G","A",0.0197,0.00324,1.09999e-09,3.62007833441893e-05,11.4161492972207]
["rs77165542","2",430975,"T","C",-0.0614,0.00795,1.10002e-14,8.14746515767773e-05,25.6947174696321]
["rs935166","2",26949366,"A","G",-0.0172,0.00277,5.39995e-10,6.10739052155885e-05,19.2605269558074]
["rs7580766","2",42939351,"G","A",0.0155,0.00282,4.30002e-08,4.4752138088564e-05,14.1129945722202]
["rs10182181","2",25150296,"G","A",0.0312,0.00252,3.19963e-35,0.000242964234129819,76.6361762615398]
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["rs10733682","9",129460914,"G","A",-0.0189,0.00264,7.50067e-13,8.03299161959512e-05,25.3336724745991]
["rs2270204","9",131042734,"G","T",0.0177,0.00302,4.49997e-09,4.57327875414556e-05,14.4222654576624]
["rs10883521","10",102439754,"T","A",0.0226,0.00344,4.90004e-11,4.67743641479557e-05,14.7507518192741]
["rs7903146","10",114758349,"T","C",-0.0212,0.00279,3.29989e-14,7.01016464924197e-05,22.1077535030729]
["rs946711","10",21806832,"C","A",0.0183,0.00309,3.50002e-09,4.59507479282444e-05,14.4910044779262]
["rs118067556","10",63136165,"T","C",-0.0435,0.00747,5.60003e-09,4.65412546007939e-05,14.6772350290197]
["rs1561589","10",126695673,"A","G",0.0167,0.0027,6.59994e-10,5.47379847533818e-05,17.2622947052796]
["rs4757142","11",13325695,"A","G",0.0193,0.00299,1.2e-10,5.98845534649707e-05,18.8854254576817]
["rs12286929","11",115022404,"G","A",0.0206,0.00254,5.50047e-16,0.000103487389161271,32.6376083159342]
["rs10840100","11",8669437,"G","A",0.0176,0.00255,5.10035e-12,6.45093689418473e-05,20.3440193288155]
["rs10742752","11",45438374,"C","T",0.015,0.00255,3.89996e-09,5.07204745279608e-05,15.9952593271631]
["rs3817334","11",47650993,"T","C",0.0232,0.00254,6.29941e-20,0.000129853589204602,40.9539981113722]
["rs592483","11",69445173,"T","C",-0.0162,0.00267,1.2e-09,5.59975794835108e-05,17.6595455940358]
["rs6265","11",27679916,"T","C",-0.0416,0.00316,1.59993e-39,0.000165099025390691,52.0717491568636]
["rs2862996","11",43653833,"T","G",-0.0179,0.00271,4.30031e-11,5.5365528808115e-05,17.4602093757202]
["rs7138803","12",50247468,"A","G",0.0274,0.00255,6.09958e-27,0.000177933680002679,56.1204820443384]
["rs2372716","12",99573426,"T","C",-0.0167,0.00301,3.09999e-08,3.37948192318289e-05,10.6573874351429]
["rs17630235","12",112591686,"A","G",-0.0159,0.00256,5e-10,5.54068293527243e-05,17.4732347387703]
["rs11170468","12",39430048,"C","A",-0.017,0.00298,1.2e-08,3.27877258789463e-05,10.339784435314]
["rs11611246","12",939480,"T","G",0.0224,0.00318,1.80011e-12,4.66292662357692e-05,14.704991644089]
["rs9513140","13",97059779,"T","C",0.0189,0.00285,3.10027e-11,6.76230079404153e-05,21.3260195685609]
["rs9512699","13",28029896,"A","G",-0.0245,0.00348,1.9002e-12,7.40912445792104e-05,23.3660347404259]
["rs12429545","13",54102206,"A","G",0.0324,0.00374,4.60045e-18,4.78919708374909e-05,15.1032168665703]
["rs9527895","13",59367767,"C","T",0.0236,0.00385,8e-10,3.8144034299786e-05,12.0289893304476]
["rs1441264","13",79580919,"A","G",0.0183,0.0026,2.09991e-12,7.7061084263277e-05,24.3027004094472]
["rs9563576","13",58670147,"T","C",-0.0218,0.0032,9.70063e-12,4.72888566996733e-05,14.9130097351388]
["rs7144011","14",79940383,"T","G",0.0288,0.00312,2.99985e-20,0.000101648868852895,32.0577211795121]
["rs11851122","14",94076978,"G","A",0.0185,0.00298,5.39995e-10,5.95584387456005e-05,18.7825745270458]
["rs10132280","14",25928179,"A","C",-0.0218,0.00279,6.20012e-15,8.4547784405215e-05,26.6639754533105]
["rs7143963","14",103304425,"T","C",0.0209,0.00321,8.19974e-11,3.55283383476556e-05,11.2040819186547]
["rs12887636","14",29702590,"G","T",-0.017,0.00268,2.19999e-10,5.57943735058851e-05,17.5954584407936]
["rs7161194","14",101529005,"G","A",-0.0185,0.00307,1.5e-09,5.26136830084704e-05,16.5923348521524]
["rs4776970","15",68080886,"T","A",-0.0258,0.00254,3.50026e-24,0.000151663076112955,47.8334473045992]
["rs8036171","15",95266810,"C","A",-0.0156,0.00255,1e-09,5.68270744809121e-05,17.9211522088346]
["rs2759315","15",81009646,"A","C",0.0185,0.00282,5.19996e-11,6.82134055390229e-05,21.5122237917487]
["rs758747","16",3627358,"T","C",0.0182,0.00301,1.5e-09,4.64685371572009e-05,14.6543018138059]
["rs889398","16",69556715,"T","C",-0.0163,0.00255,1.7e-10,6.34418644447752e-05,20.0073440465465]
["rs879620","16",4015729,"T","C",0.0246,0.00326,4.00037e-14,8.81771848803499e-05,27.808686457781]
["rs1558902","16",53803574,"A","T",0.079,0.00255,1e-200,0.00149084612617779,470.83281093179]
["rs4788099","16",28855727,"G","A",0.0289,0.00255,8.99912e-30,0.000187551967155758,59.1546696573931]
["rs749671","16",31088347,"A","G",-0.018,0.00256,1.80011e-12,7.43125300016728e-05,23.4358263489262]
["rs756717","16",72996162,"A","G",-0.0149,0.00266,2.39999e-08,4.74841312584456e-05,14.9745944273019]
["rs7193901","16",20263764,"C","T",-0.0207,0.00371,2.69998e-08,4.47982452782541e-05,14.1275355460736]
["rs11074452","16",20370168,"G","C",-0.0173,0.00288,2e-09,5.6961455640872e-05,17.963533458085]
["rs1106908","17",34942595,"A","G",-0.0179,0.00253,1.59993e-12,7.85261446464518e-05,24.7647717655852]
["rs12939549","17",78611724,"G","A",-0.0169,0.00253,2.60016e-11,6.98856316461239e-05,22.0396247645449]
["rs3026101","17",5280440,"C","T",0.0197,0.00269,2.70023e-13,6.38289271347058e-05,20.1294178664401]
["rs4986044","17",21261560,"T","C",-0.015,0.00272,3.2e-08,4.77754729746107e-05,15.0664763332115]
["rs3764400","17",46123932,"C","T",0.027,0.00374,6.00067e-13,4.37701318341536e-05,13.8032963953441]
["rs11655589","17",61608163,"G","A",0.0149,0.00271,4.20001e-08,4.13336117588368e-05,13.0348865790316]
["rs11081818","18",31251088,"A","G",0.0164,0.00283,6.4e-09,5.24257494275504e-05,16.5330647115387]
["rs17066856","18",58049656,"C","T",-0.0354,0.00432,2.70023e-16,4.72169887897741e-05,14.8903444071363]
["rs891389","18",21087531,"T","C",0.0208,0.00296,1.9002e-12,6.82813202749606e-05,21.5336432877015]
["rs6567160","18",57829135,"C","T",0.0522,0.00296,6.79986e-70,0.000384270327850295,121.224309441084]
["rs7239883","18",40147671,"A","G",-0.0158,0.00255,6.80002e-10,5.41944342574276e-05,17.0908701009446]
["rs29941","19",34309532,"G","A",0.0161,0.00269,2.5e-09,5.08350404747871e-05,16.0313907949217]
["rs2287019","19",46202172,"T","C",-0.0314,0.00347,1.29987e-19,7.13762940353583e-05,22.5097641061216]
["rs6142096","20",32686658,"A","G",0.0161,0.00282,1.09999e-08,5.14120601611624e-05,16.2133696742589]
["rs2145272","20",6626218,"A","G",0.0175,0.00268,6.29941e-11,6.16829975519166e-05,19.4526247592145]
["rs6091540","20",51087862,"T","C",-0.0229,0.00282,4.40048e-16,8.39637971269552e-05,26.479786948459]
["rs2836754","21",40291740,"C","T",0.0169,0.00259,7.39946e-11,6.28456295950872e-05,19.8193006210884]
["rs4820408","22",40604945,"G","T",-0.0163,0.0026,3.29997e-10,5.71844423334881e-05,18.0338592238366]

{"sheet":"Table S10","index":9,"n_rows":11,"n_cols":21,"rows_kept":11,"merged":[[1,1,1,3],[1,4,1,6],[1,7,1,9],[1,10,1,12],[1,13,1,17],[1,18,1,19],[2,18,2,19],[3,18,3,19],[4,18,4,19],[5,18,5,19],[6,18,6,19],[7,18,7,19],[8,18,8,19],[9,18,9,19],[10,18,10,19]],"flags":["formulas_cached_only"]}
["Supplementary table S10. MR results of IVW, weighted median, MR-Egger, contamination-mixture and MR-PRESSO methods from multiple exposures to Cervical disc disorders finn-b-M13_CERVICDISC"]
[null,"IVW",null,null,"Weighted median",null,null,"Simple mode",null,null,"Weighted mode",null,null,"MR-Egger",{"$nulls":4},"Leave one out",null,"nSNP"]
[null,"OR","95%CI","P","OR","95%CI","P","OR","95%CI","P","OR","95%CI","P","OR","95%CI","P","Pheterogeneity","Ppleiotropy","Cross the 0 axis"]
["HDL cholesterol",{"v":0.8705242,"d":"0.87"},"0.79-0.96",{"v":0.00340395,"d":"3.40E-03"},{"v":0.916881,"d":"0.92"},"0.79-1.06",{"v":0.237037091,"d":"2.37E-01"},{"v":1.0452646,"d":"1.05"},"0.79-1.39",{"v":0.761554216,"d":"7.62E-01"},{"v":0.929376,"d":"0.93"},"0.82-1.06",{"v":0.271535505,"d":"2.72E-01"},{"v":0.9432548,"d":"0.94"},"0.82-1.08",{"v":0.414041737,"d":"4.14E-01"},{"v":0.01482458,"d":"1.48E-02"},{"v":0.1352747,"d":"1.35E-01"},"No",null,258]
["LDL cholesterol",{"v":0.9214231,"d":"0.92"},"0.82-1.03",{"v":0.1518872,"d":"1.52E-01"},{"v":0.9809865,"d":"0.98"},"0.83-1.16",{"v":0.8194154,"d":"8.19E-01"},{"v":1.072241,"d":"1.07"},"0.80-1.44",{"v":0.6442754,"d":"6.44E-01"},{"v":1.005545,"d":"1.01"},"0.88-1.15",{"v":0.9365504,"d":"9.37E-01"},{"v":0.9605766,"d":"0.96"},"0.82-1.13",{"v":0.628889,"d":"6.29E-01"},{"v":0.03773775,"d":"3.77E-02"},{"v":0.4902076,"d":"4.90E-01"},"No",null,124]
["triglycerides",{"v":1.0449049,"d":"1.04"},"0.94-1.16",{"v":0.3990998,"d":"3.99E-01"},{"v":1.0306009,"d":"1.03"},"0.89-1.20",{"v":0.6919586,"d":"6.92E-01"},{"v":1.0706036,"d":"1.07"},"0.80-1.44",{"v":0.6488876,"d":"6.49E-01"},{"v":1.0070494,"d":"1.01"},"0.88-1.15",{"v":0.9160325,"d":"9.16E-01"},{"v":0.9606641,"d":"0.96"},"0.83-1.12",{"v":0.6000094,"d":"6.00E-01"},{"v":0.0008192278,"d":"8.19E-04"},{"v":0.1350966,"d":"1.35E-01"},"No",null,225]
["apolipoprotein A-I",{"v":0.8622576,"d":"0.86"},"0.78-0.95",{"v":0.003488732,"d":"3.49E-03"},{"v":0.8949216,"d":"0.89"},"0.77-1.04",{"v":0.161262205,"d":"1.61E-01"},{"v":0.9930714,"d":"0.99"},"0.71-1.39",{"v":0.967772066,"d":"9.68E-01"},{"v":0.9031639,"d":"0.90"},"0.78-1.05",{"v":0.186250395,"d":"1.86E-01"},{"v":0.9067943,"d":"0.91"},"0.77-1.06",{"v":0.232852805,"d":"2.33E-01"},{"v":0.004418425,"d":"4.42E-03"},{"v":0.4332136,"d":"4.33E-01"},"No",null,269]
["apolipoprotein B",{"v":0.9262314,"d":"0.93"},"0.84-1.02",{"v":0.10926087,"d":"1.09E-01"},{"v":0.8611136,"d":"0.86"},"0.75-0.99",{"v":0.04250925,"d":"4.25E-02"},{"v":1.264269,"d":"1.26"},"0.95-1.69",{"v":0.11230562,"d":"1.12E-01"},{"v":0.9207781,"d":"0.92"},"0.81-1.04",{"v":0.19561485,"d":"1.96E-01"},{"v":0.8861374,"d":"0.89"},"0.78-1.01",{"v":0.06273563,"d":"6.27E-02"},{"v":0.03047012,"d":"3.05E-02"},{"v":0.3086016,"d":"3.09E-01"},"No",null,184]
["circulating leptin levels",{"v":1.3024435,"d":"1.30"},"0.98-1.74",{"v":0.07327179,"d":"7.33E-02"},{"v":1.1876448,"d":"1.19"},"0.82-1.72",{"v":0.36293887,"d":"3.63E-01"},{"v":1.4412054,"d":"1.44"},"0.77-2.70",{"v":0.28331876,"d":"2.83E-01"},{"v":1.1246436,"d":"1.12"},"0.69-1.84",{"v":0.65089311,"d":"6.51E-01"},{"v":0.7615149,"d":"0.76"},"0.27-2.14",{"v":0.61955666,"d":"6.20E-01"},{"v":0.3938271,"d":"3.94E-01"},{"v":0.320579,"d":"3.21E-01"},"No",null,10]
["atherosclerosis",{"v":1.0422012,"d":"1.04"},"0.96-1.13",{"v":0.3005228,"d":"3.01E-01"},{"v":0.9135792,"d":"0.91"},"0.75-1.12",{"v":0.3875603,"d":"3.88E-01"},{"v":1.0543,"d":"1.05"},"0.96-1.12",{"v":0.3005228,"d":"3.01E-01"},{"v":0.9188608,"d":"0.92"},"0.74-1.14",{"v":0.4533678,"d":"4.53E-01"},{"v":0.9374365,"d":"0.94"},"0.80-1.11",{"v":0.4490334,"d":"4.49E-01"},{"v":0.2513905,"d":"2.51E-01"},{"v":0.1666283,"d":"1.67E-01"},"No",null,26]
["BMI",{"v":1.2750805,"d":"1.28"},"1.06-1.53",{"v":0.009600032,"d":"9.60E-03"},{"v":1.1045217,"d":"1.10"},"0.86-1.41",{"v":0.428711278,"d":"4.29E-01"},{"v":0.8249739,"d":"0.82"},"0.42-1.63",{"v":0.581289154,"d":"5.81E-01"},{"v":0.8570092,"d":"0.86"},"0.47-1.55",{"v":0.611726721,"d":"6.12E-01"},{"v":1.070966,"d":"1.07"},"0.63-1.83",{"v":0.802756539,"d":"8.03E-01"},{"v":0.004332773,"d":"4.33E-03"},{"v":0.4989502,"d":"4.99E-01"},"No",null,131]

{"sheet":"Table S11","index":10,"n_rows":11,"n_cols":21,"rows_kept":11,"merged":[[1,1,1,3],[1,4,1,6],[1,7,1,9],[1,10,1,12],[1,13,1,17],[1,18,1,19],[2,18,2,19],[3,18,3,19],[4,18,4,19],[5,18,5,19],[6,18,6,19],[7,18,7,19],[8,18,8,19],[9,18,9,19],[10,18,10,19]],"flags":["formulas_cached_only"]}
["Supplementary table S11. MR results of IVW, weighted median, MR-Egger, contamination-mixture and MR-PRESSO methods from multiple exposures to Other intervertebral disc disorders finn-b-M13_INTERVERTEB."]
[null,"IVW",null,null,"Weighted median",null,null,"Simple mode",null,null,"Weighted mode",null,null,"MR-Egger",{"$nulls":4},"Leave one out",null,"nSNP"]
[null,"OR","95%CI","P","OR","95%CI","P","OR","95%CI","P","OR","95%CI","P","OR","95%CI","P","Pheterogeneity","Ppleiotropy","Cross the 0 axis"]
["HDL cholesterol",{"v":0.9293722,"d":"0.93"},"0.87-0.99",{"v":0.02155398,"d":"2.16E-02"},{"v":0.9720434,"d":"0.97"},"0.88-1.07",{"v":0.57013178,"d":"5.70E-01"},{"v":0.9235914,"d":"0.92"},"0.77-1.11",{"v":0.39889864,"d":"3.99E-01"},{"v":0.9625817,"d":"0.96"},"0.89-1.05",{"v":0.356836029,"d":"3.57E-01"},{"v":0.974986,"d":"0.97"},"0.89-1.07",{"v":0.59921075,"d":"5.99E-01"},{"v":0.0009556259,"d":"9.56E-04"},{"v":0.1858652,"d":"1.86E-01"},"No",null,258]
["LDL cholesterol",{"v":0.9922363,"d":"0.99"},"0.92-1.07",{"v":0.8435611,"d":"8.44E-01"},{"v":1.0516144,"d":"1.05"},"0.94-1.17",{"v":0.35654,"d":"3.57E-01"},{"v":1.1358209,"d":"1.14"},"0.90-1.43",{"v":0.27522,"d":"2.75E-01"},{"v":1.0561439,"d":"1.06"},"0.96-1.16",{"v":0.2698055,"d":"2.70E-01"},{"v":1.0105549,"d":"1.01"},"0.90-1.13",{"v":0.8553497,"d":"8.55E-01"},{"v":0.00178839,"d":"1.79E-03"},{"v":0.6611317,"d":"6.61E-01"},"YES",null,124]
["triglycerides",{"v":1.078971,"d":"1.08"},"1.01-1.15",{"v":0.01975618,"d":"1.98E-02"},{"v":1.0396339,"d":"1.04"},"0.95-1.14",{"v":0.41838787,"d":"4.18E-01"},{"v":1.022974,"d":"1.02"},"0.85-1.24",{"v":0.8142313,"d":"8.14E-01"},{"v":1.022974,"d":"1.02"},"0.94-1.11",{"v":0.58288658,"d":"5.83E-01"},{"v":0.9637031,"d":"0.96"},"0.87-1.06",{"v":0.45784204,"d":"4.58E-01"},{"v":4.051428e-05,"d":"4.05E-05"},{"v":0.0006722566,"d":"6.72E-04"},"No",null,225]
["apolipoprotein A-I",{"v":0.9317395,"d":"0.93"},"0.87-0.99",{"v":0.0299988,"d":"3.00E-02"},{"v":0.9404003,"d":"0.94"},"0.86-1.03",{"v":0.19996293,"d":"2.00E-01"},{"v":1.0431296,"d":"1.04"},"0.85-1.27",{"v":0.68000456,"d":"6.80E-01"},{"v":0.9599793,"d":"0.96"},"0.87-1.06",{"v":0.398883,"d":"3.99E-01"},{"v":0.9111346,"d":"0.91"},"0.82-1.01",{"v":0.07780172,"d":"7.78E-02"},{"v":0.008622439,"d":"8.62E-03"},{"v":0.6122058,"d":"6.12E-01"},"No",null,268]
["apolipoprotein B",{"v":1.032768,"d":"1.03"},"0.97-1.10",{"v":0.32583177,"d":"3.26E-01"},{"v":1.065709,"d":"1.07"},"0.97-1.17",{"v":0.18991199,"d":"1.90E-01"},{"v":1.264269,"d":"1.26"},"1.03-1.55",{"v":0.02444496,"d":"2.44E-02"},{"v":1.052152,"d":"1.05"},"0.97-1.14",{"v":0.21346809,"d":"2.13E-01"},{"v":1.016405,"d":"1.02"},"0.93-1.11",{"v":0.71430008,"d":"7.14E-01"},{"v":0.001154699,"d":"1.15E-03"},{"v":0.5927431,"d":"5.93E-01"},"No",null,184]
["circulating leptin levels",{"v":1.0244256,"d":"1.02"},"0.77-1.36",{"v":0.8675403,"d":"8.68E-01"},{"v":0.9175124,"d":"0.92"},"0.71-1.19",{"v":0.5140596,"d":"5.14E-01"},{"v":0.8825769,"d":"0.88"},"0.59-1.32",{"v":0.5570404,"d":"5.57E-01"},{"v":0.8577915,"d":"0.86"},"0.59-1.24",{"v":0.4345172,"d":"4.35E-01"},{"v":0.7333808,"d":"0.73"},"0.26-2.11",{"v":0.5801933,"d":"5.80E-01"},{"v":0.009474588,"d":"9.47E-03"},{"v":0.5358899,"d":"5.36E-01"},"No",null,10]
["atherosclerosis",{"v":1.065088,"d":"1.07"},"1.02-1.12",{"v":0.008261699,"d":"8.26E-03"},{"v":1.077458,"d":"1.08"},"1.01-1.15",{"v":0.023836065,"d":"2.38E-02"},{"v":1.117336,"d":"1.12"},"0.99-1.26",{"v":0.086683106,"d":"8.67E-02"},{"v":1.110142,"d":"1.11"},"0.98-1.25",{"v":0.10128006,"d":"1.01E-01"},{"v":1.073477,"d":"1.07"},"0.97-1.19",{"v":0.178591343,"d":"1.79E-01"},{"v":0.9259856,"d":"9.26E-01"},{"v":0.8638296,"d":"8.64E-01"},"No",null,26]
["BMI",{"v":1.259614,"d":"1.26"},"1.12-1.42",{"v":0.0001590563,"d":"1.59E-04"},{"v":1.244082,"d":"1.24"},"1.06-1.47",{"v":0.0089855304,"d":"8.99E-03"},{"v":1.197101,"d":"1.20"},"0.80-1.78",{"v":0.3788513876,"d":"3.79E-01"},{"v":1.263886,"d":"1.26"},"0.88-1.82",{"v":0.213105676,"d":"2.13E-01"},{"v":1.251465,"d":"1.25"},"0.88-1.78",{"v":0.2119809066,"d":"2.12E-01"},{"v":0.003238404,"d":"3.24E-03"},{"v":0.9692377,"d":"9.69E-01"},"No",null,131]

{"sheet":"Table S12","index":11,"n_rows":9,"n_cols":8,"rows_kept":9,"flags":["formulas_cached_only"]}
["Supplementary table S12. Multivariate Mendelian randomization results for Cervical disc disorders"]
[null,"beta","se","P","or","or_lci95","or_uci95","nSNP"]
["Body mass index",{"v":0.1176882,"d":"0.12"},{"v":0.09689064,"d":"0.10"},{"v":0.23439532,"d":"2.34E-01"},{"v":1.1196304,"d":"1.12"},{"v":0.9293632,"d":"0.93"},{"v":1.348851,"d":"1.35"},372]
["Apolipoprotein A-I",{"v":-0.3073907,"d":"-0.31"},{"v":0.17718866,"d":"0.18"},{"v":0.07608926,"d":"7.61E-02"},{"v":0.7333519,"d":"0.73"},{"v":0.520583,"d":"0.52"},{"v":1.033082,"d":"1.03"},372]
["HDL cholesterol",{"v":0.1782105,"d":"0.18"},{"v":0.17025203,"d":"0.17"},{"v":0.29151979,"d":"2.92E-01"},{"v":1.194027,"d":"1.19"},{"v":0.858831,"d":"0.86"},{"v":1.660048,"d":"1.66"},372]
[]
["Atherosclerosis",{"v":0.0770678,"d":"0.08"},{"v":0.0429296,"d":"0.04"},{"v":0.07612367,"d":"7.61E-02"},{"v":1.0781332,"d":"1.08"},{"v":0.9921262,"d":"0.99"},{"v":1.171596,"d":"1.17"},335]
["Apolipoprotein A-I",{"v":-0.3427285,"d":"-0.34"},{"v":0.1715825,"d":"0.17"},{"v":0.03369938,"d":"3.37E-02"},{"v":0.6936214,"d":"0.69"},{"v":0.4948667,"d":"0.49"},{"v":0.9722025,"d":"0.97"},335]
["HDL cholesterol",{"v":0.2098054,"d":"0.21"},{"v":0.1644666,"d":"0.16"},{"v":0.16787924,"d":"1.68E-01"},{"v":1.2559759,"d":"1.26"},{"v":0.9084528,"d":"0.91"},{"v":1.736442,"d":"1.74"},335]

{"sheet":"Table S13","index":12,"n_rows":10,"n_cols":7,"rows_kept":10,"flags":["formulas_cached_only"]}
["Supplementary table S13. Multivariate Mendelian randomization results for Other intervertebral disc disorders"]
[null,"beta","se","P","or","or_lci95","or_uci95"]
["BMI",{"v":0.2098022,"d":"0.21"},{"v":0.06284712,"d":"0.06"},{"v":0.0008429442,"d":"8.43E-04"},{"v":1.233434,"d":"1.23"},{"v":1.0902429,"d":"1.09"},{"v":1.394826,"d":"1.39"}]
["ApoA-1",{"v":0.1388446,"d":"0.14"},{"v":0.11581201,"d":"0.12"},{"v":0.2305748259,"d":"2.31E-01"},{"v":1.1489456,"d":"1.15"},{"v":0.9156338,"d":"0.92"},{"v":1.441752,"d":"1.44"}]
["HDL",{"v":-0.2085792,"d":"-0.21"},{"v":0.11135921,"d":"0.11"},{"v":0.061064148,"d":"6.11E-02"},{"v":0.8117367,"d":"0.81"},{"v":0.6525502,"d":"0.65"},{"v":1.009722,"d":"1.01"}]
[]
[null,"beta","se","P","or","or_lci95","or_uci95"]
["AS",{"v":0.07071796,"d":"0.07"},{"v":0.02764426,"d":"0.03"},{"v":0.01052328,"d":"1.05E-02"},{"v":1.0732785,"d":"1.07"},{"v":1.0166761,"d":"1.02"},{"v":1.133047,"d":"1.13"}]
["ApoA-1",{"v":0.07144063,"d":"0.07"},{"v":0.11239776,"d":"0.11"},{"v":0.52503364,"d":"5.25E-01"},{"v":1.0740544,"d":"1.07"},{"v":0.8617151,"d":"0.86"},{"v":1.338784,"d":"1.34"}]
["HDL",{"v":-0.1342183,"d":"-0.13"},{"v":0.10782467,"d":"0.11"},{"v":0.21321161,"d":"2.13E-01"},{"v":0.8743992,"d":"0.87"},{"v":0.7078182,"d":"0.71"},{"v":1.080147,"d":"1.08"}]

{"sheet":"Table S14","index":13,"n_rows":8,"n_cols":6,"rows_kept":8,"flags":["formulas_cached_only"]}
["Supplementary table S14. Multivariate Mendelian effect ofAA1\\HDL  on Cervical disc disorders/Other intervertebral disc disorders."]
["expose","nsnp","b","se","p","outcome"]
["apolipoprotein A-I",561,{"v":-0.3133138,"d":"-0.31"},{"v":0.1700642,"d":"0.17"},{"v":0.06542732,"d":"6.54E-02"},"CDD"]
["HDL cholesterol",561,{"v":0.157398,"d":"0.16"},{"v":0.1606752,"d":"0.16"},{"v":0.32728198,"d":"3.27E-01"},"CDD"]
[]
["expose","nsnp","b","se","p","outcome"]
["apolipoprotein A-I",344,{"v":0.1201474,"d":"0.12"},{"v":0.1115427,"d":"0.11"},{"v":0.28141659,"d":"2.81E-01"},"NCDD"]
["HDL cholesterol",344,{"v":-0.200475,"d":"-0.20"},{"v":0.1053852,"d":"0.11"},{"v":0.05713103,"d":"5.71E-02"},"NCDD"]

{"sheet":"Table S15","index":14,"n_rows":6,"n_cols":6,"rows_kept":6,"flags":["formulas_cached_only"]}
["Supplementary table S15. Multivariate Mendelian effect of AA1\\HDL\\BMI\\AS on Cervical disc disorders."]
["expose","nsnp","b","se","p","or"]
["apolipoprotein A-I",238,{"v":-0.42683142,"d":"-0.43"},{"v":0.21175512,"d":"0.21"},{"v":0.04383302,"d":"4.38E-02"},{"v":0.6525736,"d":"0.65"}]
["HDL cholesterol",238,{"v":0.26327064,"d":"0.26"},{"v":0.19732518,"d":"0.20"},{"v":0.18213933,"d":"1.82E-01"},{"v":1.3011788,"d":"1.30"}]
["BMI",238,{"v":0.03506515,"d":"0.04"},{"v":0.10877087,"d":"0.11"},{"v":0.74716764,"d":"7.47E-01"},{"v":1.0356872,"d":"1.04"}]
["Atherosclerosis",238,{"v":0.08251549,"d":"0.08"},{"v":0.05176017,"d":"0.05"},{"v":0.11089372,"d":"1.11E-01"},{"v":1.0860155,"d":"1.09"}]

{"sheet":"Table S16","index":15,"n_rows":6,"n_cols":8,"rows_kept":6,"flags":["formulas_cached_only"]}
["Supplementary table S16. Multivariate Mendelian effect of AA1\\HDL\\BMI\\AS on Other intervertebral disc disorders"]
[null,"beta","se","P","or","or_lci95","or_uci95","nSNP"]
["HDL",{"v":-0.13752851,"d":"-0.14"},{"v":0.11453827,"d":"0.11"},{"v":0.229859429,"d":"2.30E-01"},{"v":0.8715095,"d":"0.87"},{"v":0.696266,"d":"0.70"},{"v":1.09086,"d":"1.09"},366]
["ApoA-1",{"v":0.08542644,"d":"0.09"},{"v":0.11723458,"d":"0.12"},{"v":0.466197686,"d":"4.66E-01"},{"v":1.0891814,"d":"1.09"},{"v":0.8655819,"d":"0.87"},{"v":1.370542,"d":"1.37"},366]
["AS",{"v":0.07017896,"d":"0.07"},{"v":0.02817377,"d":"0.03"},{"v":0.012740814,"d":"1.27E-02"},{"v":1.0727001,"d":"1.07"},{"v":1.0150708,"d":"1.02"},{"v":1.133601,"d":"1.13"},366]
["BMI",{"v":0.19575467,"d":"0.20"},{"v":0.06301298,"d":"0.06"},{"v":0.001892669,"d":"1.89E-03"},{"v":1.2162285,"d":"1.22"},{"v":1.0749232,"d":"1.07"},{"v":1.376109,"d":"1.38"},366]

{"sheet":"Table S17","index":16,"n_rows":42,"n_cols":13,"rows_kept":42,"flags":["formulas_cached_only"]}
["Supplementary table S17. BMI BetaXY、BetaXZ、BetaZY、BetaXY'、Mediator"]
[null,"BetaXY","BetaZY","BetaXZ","BetaXY'","BMI Mediator","Cl95% Mediator"]
["HDL-ODD",{"v":-0.08316602,"d":"-0.08"},{"v":0.2215237,"d":"0.22"},{"v":-0.045973403,"d":"-0.05"},{"v":-0.0642768,"d":"-0.06"},{"v":0.1549,"d":"15.49%"},"3.23%-27.71%"]
["AA1-ODD",{"v":-0.07211076,"d":"-0.07"},{"v":0.22415142,"d":"0.22"},{"v":-0.07070198,"d":"-0.07"},{"v":-0.06644961,"d":"-0.07"},{"v":0.1765,"d":"17.65%"},"2.78%-32.03%"]
[]
[]
[null,"BetaXZ","SeXZ","PXZ","  ORXZ","or_lci95XZ","or_uci95XZ"]
["HDL-BMI",{"v":-0.045973403,"d":"-0.05"},{"v":0.0183552,"d":"0.02"},{"v":0.01225714,"d":"0.01"},{"v":0.9550674,"d":"0.96"},{"v":0.9213184,"d":"0.92"},{"v":0.9900526,"d":"0.99"}]
["AA1-BMI",{"v":-0.07070198,"d":"-0.07"},{"v":0.03257996,"d":"0.03"},{"v":0.0299988,"d":"0.03"},{"v":0.9317395,"d":"0.93"},{"v":0.8741016,"d":"0.87"},{"v":0.9931781,"d":"0.99"}]
[]
[]
[]
[null,"BetaZY","SeZY","PZY","ORZY","or_lci95ZY","or_uci95ZY","BetaXY'","SeXY'","PXY'","ORXY'","or_lci95XY'","or_uci95XY'"]
["HDL/BMI-ODD",{"v":0.2215237,"d":"0.22"},{"v":0.06255313,"d":"0.06"},{"v":0.0003980558,"d":"3.98E-04"},{"v":1.2512605,"d":"1.25"},{"v":1.1080677,"d":"1.11"},{"v":1.412958,"d":"1.41"},{"v":-0.0642768,"d":"-0.06"},{"v":0.03597194,"d":"0.04"},{"v":0.0739602316,"d":"7.40E-02"},{"v":0.9377454,"d":"0.94"},0.87,1.01]
["AA1/BMI-ODD",{"v":0.22415142,"d":"0.22"},{"v":0.06200702,"d":"0.06"},{"v":-0.06644961,"d":"-6.64E-02"},{"v":1.2479769,"d":"1.25"},{"v":1.1039775,"d":"1.10"},{"v":1.410759,"d":"1.41"},{"v":-0.06644961,"d":"-0.07"},{"v":0.03577145,"d":"0.04"},{"v":0.0632235557,"d":"6.32E-02"},{"v":0.9357101,"d":"0.94"},0.87,{"v":1,"d":"1.00"}]
{"$rows_empty":18}
[null,"betaXY1","se","P","OR","95%Cl","betaZY","se","P","OR","95%Cl"]
["HDL adjusted for BMI",{"v":-0.07325362,"d":"-0.07"},{"v":0.04114168,"d":"0.04"},{"v":0.07499073,"d":"0.07"},{"v":0.9293651,"d":"0.93"},"0.86-1.01"]
["BMI adjusted for HDL",{"$nulls":5},{"v":0.17060944,"d":"0.17"},{"v":0.07570749,"d":"0.08"},{"v":0.02422548,"d":"0.02"},{"v":1.1860274,"d":"1.19"},"1.02-1.38"]
[]
["AA adjusted for BMI",{"v":-0.04363033,"d":"-0.04"},{"v":0.0466104,"d":"0.05"},{"v":0.349240174,"d":"0.35"},{"v":0.9573078,"d":"0.96"},"0.87-1.05"]
["BMI adjusted for AA",{"$nulls":5},{"v":0.21425844,"d":"0.21"},{"v":0.07636259,"d":"0.08"},{"v":0.005019124,"d":"0.01"},{"v":1.2389428,"d":"1.24"},"1.07-1.44"]
[]
["TRI adjusted for BMI",{"v":0.1121255,"d":"0.11"},{"v":0.03945104,"d":"0.04"},{"v":0.004703655,"d":"4.70E-03"},{"v":1.11797,"d":"1.12"},"1.03-1.21"]
["BMI adjusted for TRI",{"$nulls":5},{"v":0.289169,"d":"0.29"},{"v":0.07254111,"d":"0.07"},{"v":6.958099e-05,"d":"6.96E-05"},1.33,"1.16-1.54"]

{"sheet":"Table S18","index":17,"n_rows":13,"n_cols":9,"rows_kept":13,"flags":["formulas_cached_only"]}
["Supplementary table S18. AS BetaXY、BetaXZ、BetaZY、BetaXY'、Mediator"]
[null,"BetaXY","BetaZY","BetaXZ","BetaXY'","AS Mediator","Cl95% Mediator"]
["HDL-ODD",{"v":-0.08316602,"d":"-0.08"},{"v":0.1032814,"d":"0.10"},{"v":-0.2940313,"d":"-0.29"},{"v":-0.0565053,"d":"-0.06"},{"v":0.3258,"d":"32.58%"},"14.29%-46.43%"]
["AA1-ODD",{"v":-0.07211076,"d":"-0.07"},{"v":0.08319393,"d":"0.08"},{"v":-0.17685875,"d":"-0.18"},{"v":-0.06127801,"d":"-0.06"},{"v":0.1935,"d":"19.35%"},"1.64%-38.78%"]
[]
[]
[null,"BetaXZ","SeXZ","PXZ"]
["HDL-AS",{"v":-0.2940313,"d":"-0.29"},{"v":0.05809922,"d":"0.06"},{"v":4.173955e-07,"d":"4.17E-07"}]
["AA1-AS",{"v":-0.17685875,"d":"-0.18"},{"v":0.1017246,"d":"0.10"},{"v":0.08210441,"d":"8.21E-02"}]
[]
[null,"BetaZY","SeZY","PZY","BetaXY'","SeXY'","PXY'","ORXY'","or_lci95XY'—or_uci95XY'"]
["HDL/AS-ODD",{"v":0.1032814,"d":"0.10"},{"v":0.02904242,"d":"0.03"},{"v":0.000376222,"d":"3.76E-04"},{"v":-0.0565053,"d":"-0.06"},{"v":0.03311885,"d":"0.03"},{"v":0.087982571,"d":"8.80E-02"},{"v":0.9450615,"d":"0.95"},"0.8856635-1.008443"]
["AA1/AS-ODD",{"v":0.08319393,"d":"0.08"},{"v":0.03080171,"d":"0.03"},{"v":0.006914139,"d":"6.91E-03"},{"v":-0.06127801,"d":"-0.06"},{"v":0.03275353,"d":"0.03"},{"v":0.061361295,"d":"6.14E-02"},{"v":0.9405617,"d":"0.94"},"0.8820779-1.002923"]