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[null,"cHCC-CCA (n=19)","HCC (n=742)","iCCA (n=121)","Statistical analysis"]
["Sex","Male: 12\nFemale: 7","Male: 583\nFemale: 159","Male: 72\nFemale: 49","p<0.0001"]
["Age","64.1 ± 10.6","66.7 ± 9.7","66.7 ± 10.0","NS"]
["Platelet number (×104/μL)","17.2 ± 10.7","13.6 ± 7.8","19.1 ± 9.0","HCC vs. iCCA: p<0.0001"]
["Total bilirubin (mg/dL)","1.19 ± 0.71","1.05 ± 1.21","0.89 ± 0.72","NS"]
["Albumin (g/dL)","3.91 ± 0.50","3.82 ± 0.54","3.99 ± 0.47","HCC vs. iCCA: p=0.0032"]
["Prothrombin time (%)","83.6 ± 12.0","83.7 ± 15.7","91.6 ± 16.0","HCC vs. iCCA: p<0.0001"]
["HBsAg","Positive: 3 (15.8%)\nNegative: 16 (84.2%)\nMissing data: 0","Positive: 147 (19.8%)\nNegative: 588 (79.2%)\nMissing data: 7","Positive: 7 (5.8%)\nNegative: 109 (90.1%)\nMissing data: 5","p<0.0001"]
["HCV-Ab","Positive: 8 (42.1%)\nNegative: 11 (57.9%)\nMissing data: 0","Positive: 336 (45.3%)\nNegative: 400 (53.9%)\nMissing data: 6","Positive: 16 (13.2%)\nNegative: 102 (84.3%)\nMissing data: 3","p<0.0001"]
["AFP (ng/mL)","110.7 ± 343.5","7416 ± 108118.1","12.6 ± 49.3","NS"]
["DCP (mAU/mL)","1613.3 ± 5099.2","7895.5 ± 35673.2","693.1 ± 3890.6","NS"]
["CEA (ng/mL)","2.88 ± 3.01","3.65 ± 2.61","7.36 ± 18.9","HCC vs. iCCA: p=0.0015"]
["CA19-9 (U/mL)","37.2 ± 31.6","48.3 ± 55.1","308.7 ± 760.4","HCC vs. iCCA: p<0.0001\ncHCC-CCA vs. iCCA: p=0.0294"]
["Tumor number","1.21 ± 0.42","1.68 ± 1.56","1.48 ± 1.70","NS"]
["Tumor size (cm)","4.07 ± 2.39","4.68 ± 4.19","4.63 ± 2.75","NS"]
["Major portal vein invasion","Presence: 3 (15.8%)\nAbsence: 16 (84.2%)\nMissing data: 0","Presence: 67 (9.0%)\nAbsence: 618 (83.3%)\nMissing data: 57","Presence: 14 (11.6%)\nAbsence: 94 (77.7%)\nMissing data: 13","NS"]
["Major hepatic vein invasion","Presence: 0 (0%)\nAbsence: 19 (100%)\nMissing data: 0","Presence: 25 (3.4%)\nAbsence: 658 (88.7%)\nMissing data: 59","Presence: 9 (7.4%)\nAbsence: 99 (81.8%)\nMissing data: 13","NS"]
["Major biliary tract invasion","Presence: 7 (36.8%)\nAbsence: 12 (63.2%)\nMissing data: 0","Presence: 37 (5.0%)\nAbsence: 646 (87.1%)\nMissing data: 59","Presence: 22 (18.2%)\nAbsence: 80 (66.1%)\nMissing data: 19","p<0.0001"]
["Surgical procedure","AR: 13 (68.4%)\nNAR: 6 (31.6%)","AR: 471 (63.5%)\nNAR: 271 (36.5%) ","AR: 95 (78.5%)\nNAR: 26 (21.5%)","p=0.0053"]
["Resection of \nextrahepatic bile duct","Presence: 1 (5.3%)\nAbsence: 18 (94.7%)","Presence: 3 (0.4%)\nAbsence: 739 (99.6%)","Presence: 29 (24.0%)\nAbsence: 92 (76.0%)","p<0.0001"]
["Lymph node dissection","Presence: 1 (5.3%)\nAbsence: 18 (94.7%)","Presence: 9 (1.2%)\nAbsence: 733 (98.8%)","Presence: 93 (76.9%)\nAbsence: 28 (23.1%)","p<0.0001"]