{"text_format":"3","workbook":"xlsx","n_sheets":5,"sheets":["TableS1","TableS2-S5","TableS6","TableS7","TableS8"],"read":"whole","date_system":"1900"}

{"sheet":"TableS1","index":0,"n_rows":7,"n_cols":6,"rows_kept":7}
["Table-S1:Collected data"]
["year","Papers","data","cancertype","cellnumber"]
[2021,"This paper",null,"rectal carcinoma",9670,"Chromium"]
[2020,"A pan-cancer blueprint of the heterogeneous tumor microenvironment revealed by single-cell profiling","E-MTAB-8107","Colorectal Cancer",25432,"Chromium"]
[2020,"Lineage-dependent gene expression programs influence the immune landscape of colorectal cancer.","GSE144735","Colorectal Cancer",11866,"Chromium"]
[2020,"Lineage-dependent gene expression programs influence the immune landscape of colorectal cancer.","GSE132257","Colorectal Cancer",8837,"Chromium"]
[2020,"Lineage-dependent gene expression programs influence the immune landscape of colorectal cancer.","GSE132465","Colorectal Cancer",43884,"Chromium"]

{"sheet":"TableS2-S5","index":1,"n_rows":53,"n_cols":14,"rows_kept":53}
[]
["Table-S2:Patients cell number statistics",{"$nulls":3},"Table-S3:Samples cell number statistics",null,null,"Table-S4:Clinical stage cell number statistics",{"$nulls":3},"Table-S5:Cluster cell number statistics"]
[null,"V1",null,null,"Samples","cell number",null,"Stage","cell number","samples numbers",null,"Cluster","SingleR","cell number"]
["CC1",{"v":3911,"d":"3,911"},null,null,"CC1",{"v":3911,"d":"3,911"},null,"StageI",{"v":16796,"d":"16,796"},7,null,0,"Epithelial_cells",{"v":17586,"d":"17,586"}]
["CC2",{"v":5759,"d":"5,759"},null,null,"CC2",{"v":5759,"d":"5,759"},null,"StageII",{"v":28350,"d":"28,350"},18,null,1,"T_cells",{"v":17268,"d":"17,268"}]
["KUL01",{"v":4051,"d":"4,051"},null,null,"KUL01-B",{"v":2129,"d":"2,129"},null,"StageIII",{"v":54543,"d":"54,543"},24,null,2,"T_cells",{"v":12327,"d":"12,327"}]
["KUL19",{"v":6391,"d":"6,391"},null,null,"KUL01-T",{"v":1922,"d":"1,922"},{"$nulls":5},3,"Macrophage",{"v":11726,"d":"11,726"}]
["KUL28",834,null,null,"KUL19-B",{"v":3263,"d":"3,263"},{"$nulls":5},4,"Epithelial_cells",{"v":10625,"d":"10,625"}]
["KUL30",{"v":1318,"d":"1,318"},null,null,"KUL19-T",{"v":3128,"d":"3,128"},{"$nulls":5},5,"B_cell",{"v":5688,"d":"5,688"}]
["KUL31",{"v":1194,"d":"1,194"},null,null,"KUL28-B",406,{"$nulls":5},6,"Fibroblasts",{"v":4068,"d":"4,068"}]
["scrEXT001",{"v":2712,"d":"2,712"},null,null,"KUL28-T",428,{"$nulls":5},7,"Epithelial_cells",{"v":3717,"d":"3,717"}]
["scrEXT002",{"v":2901,"d":"2,901"},null,null,"KUL30-B",766,{"$nulls":5},8,"Endothelial_cells",{"v":3661,"d":"3,661"}]
["scrEXT009",{"v":4936,"d":"4,936"},null,null,"KUL30-T",552,{"$nulls":5},9,"B_cell",{"v":3608,"d":"3,608"}]
["scrEXT010",{"v":4461,"d":"4,461"},null,null,"KUL31-B",{"v":1119,"d":"1,119"},{"$nulls":5},10,"Epithelial_cells",{"v":2454,"d":"2,454"}]
["scrEXT018",{"v":3770,"d":"3,770"},null,null,"KUL31-T",75,{"$nulls":5},11,"T_cells",{"v":2104,"d":"2,104"}]
["scrEXT019",{"v":2271,"d":"2,271"},null,null,"scrEXT001",{"v":2712,"d":"2,712"},{"$nulls":5},12,"Tissue_stem_cells",{"v":1817,"d":"1,817"}]
["scrEXT021",709,null,null,"scrEXT002",{"v":2901,"d":"2,901"},{"$nulls":5},13,"B_cell",{"v":1769,"d":"1,769"}]
["scrEXT022",621,null,null,"scrEXT009",{"v":4936,"d":"4,936"},{"$nulls":5},14,"CMP",613]
["scrEXT024",530,null,null,"scrEXT010",{"v":4461,"d":"4,461"},{"$nulls":5},15,"Monocyte",392]
["scrEXT025",720,null,null,"scrEXT018",{"v":3770,"d":"3,770"},{"$nulls":5},16,"T_cells",266]
["scrEXT027",747,null,null,"scrEXT019",{"v":2271,"d":"2,271"}]
["scrEXT028",{"v":1054,"d":"1,054"},null,null,"scrEXT021",709]
["SMC01",{"v":2791,"d":"2,791"},null,null,"scrEXT022",621]
["SMC02",{"v":1689,"d":"1,689"},null,null,"scrEXT024",530]
["SMC03",{"v":2123,"d":"2,123"},null,null,"scrEXT025",720]
["SMC04",{"v":1841,"d":"1,841"},null,null,"scrEXT027",747]
["SMC05",660,null,null,"scrEXT028",{"v":1054,"d":"1,054"}]
["SMC06",{"v":1541,"d":"1,541"},null,null,"SMC01-T",{"v":2791,"d":"2,791"}]
["SMC07",{"v":4070,"d":"4,070"},null,null,"SMC02-T",{"v":1689,"d":"1,689"}]
["SMC08",{"v":2089,"d":"2,089"},null,null,"SMC03-T",{"v":2123,"d":"2,123"}]
["SMC09",{"v":3789,"d":"3,789"},null,null,"SMC04-T",{"v":1841,"d":"1,841"}]
["SMC10",{"v":2200,"d":"2,200"},null,null,"SMC05-T",660]
["SMC11",{"v":1698,"d":"1,698"},null,null,"SMC06-T",{"v":1541,"d":"1,541"}]
["SMC13T.A1",{"v":2411,"d":"2,411"},null,null,"SMC07-T",{"v":4070,"d":"4,070"}]
["SMC14",{"v":1749,"d":"1,749"},null,null,"SMC08-T",{"v":2089,"d":"2,089"}]
["SMC15",{"v":2027,"d":"2,027"},null,null,"SMC09-T",{"v":3789,"d":"3,789"}]
["SMC16",{"v":2956,"d":"2,956"},null,null,"SMC10-T",{"v":2200,"d":"2,200"}]
["SMC17",{"v":1343,"d":"1,343"},null,null,"SMC11-T",{"v":1698,"d":"1,698"}]
["SMC171",{"v":5083,"d":"5,083"},null,null,"SMC13T.A1",{"v":2411,"d":"2,411"}]
["SMC18",{"v":1936,"d":"1,936"},null,null,"SMC14-T",{"v":1749,"d":"1,749"}]
["SMC19",{"v":1540,"d":"1,540"},null,null,"SMC15-T",{"v":2027,"d":"2,027"}]
["SMC20",{"v":1681,"d":"1,681"},null,null,"SMC16-T",{"v":2956,"d":"2,956"}]
["SMC22",{"v":2363,"d":"2,363"},null,null,"SMC17-T",{"v":1343,"d":"1,343"}]
["SMC23",{"v":1639,"d":"1,639"},null,null,"SMC171.T.BEL",{"v":1652,"d":"1,652"}]
["SMC24",{"v":1580,"d":"1,580"},null,null,"SMC171.T.SGI",{"v":1660,"d":"1,660"}]
[" ",{"$nulls":3},"SMC171.T.SING",{"v":1771,"d":"1,771"}]
[{"$nulls":4},"SMC18-T",{"v":1936,"d":"1,936"}]
[{"$nulls":4},"SMC19-T",{"v":1540,"d":"1,540"}]
[{"$nulls":4},"SMC20-T",{"v":1681,"d":"1,681"}]
[{"$nulls":4},"SMC22-T",{"v":2363,"d":"2,363"}]
[{"$nulls":4},"SMC23-T",{"v":1639,"d":"1,639"}]
[{"$nulls":4},"SMC24-T",{"v":1580,"d":"1,580"}]
[{"$nulls":4}," "]

{"sheet":"TableS6","index":2,"n_rows":163,"n_cols":7,"rows_kept":163}
["Table-S6:Marker genes first annotation"]
["p_val","avg_log2FC","pct.1","pct.2","p_val_adj","cluster","gene"]
[0,"Inf",0.519,0.326,0,0,"IFI6"]
[0,"Inf",0.982,0.681,0,0,"S100A11"]
[0,"Inf",0.986,0.94,0,0,"RPL37A"]
[0,"Inf",0.996,0.96,0,0,"PTMA"]
[0,"Inf",0.671,0.162,0,0,"CXCL1"]
[0,"Inf",0.736,0.203,0,0,"CXCL3"]
[0,"Inf",0.613,0.2,0,0,"CXCL2"]
[0,"Inf",0.988,0.96,0,0,"RPS14"]
[0,"Inf",0.947,0.588,0,0,"SEC61G"]
[0,"Inf",0.988,0.942,0,0,"RPL30"]
[0,"Inf",0.989,0.957,0,0,"RPS6"]
[0,"Inf",0.267,0.07,0,0,"SPINK4"]
[0,"Inf",0.992,0.957,0,0,"RPL12"]
[0,"Inf",0.989,0.951,0,0,"RPS24"]
[0,"Inf",0.991,0.964,0,0,"RPLP2"]
[0,"Inf",0.974,0.723,0,0,"NEAT1"]
[0,"Inf",0.328,0.03,0,0,"GAL"]
[0,"Inf",0.989,0.954,0,0,"RPS3"]
[0,"Inf",0.994,0.903,0,0,"GAPDH"]
[0,"Inf",0.995,0.362,0,0,"KRT8"]
[0,"Inf",0.995,0.978,0,0,"RPL41"]
[0,"Inf",0.693,0.122,0,0,"CKB"]
[0,"Inf",0.862,0.301,0,0,"PHGR1"]
[0,"Inf",0.971,0.927,0,0,"RPS17"]
[0,"Inf",0.983,0.241,0,0,"KRT19"]
[0,"Inf",0.99,0.907,0,0,"EIF1"]
[0,"Inf",0.991,0.945,0,0,"RPL36"]
[0,"Inf",0.989,0.958,0,0,"RPL18A"]
[0,"Inf",0.994,0.972,0,0,"RPL28"]
[0,"Inf",0.985,0.894,0,0,"RPS21"]
[0,"Inf",0.623,0.108,0,0,"TFF1"]
[0,"Inf",0.989,0.719,0,0,"SAT1"]
[0,"Inf",0.993,0.936,0,0,"MT-ND3"]
[{"v":5.17776588212932e-52,"d":"5.18E-52"},"Inf",0.683,0.634,{"v":1.85488284961401e-47,"d":"1.85E-47"},0,"S100A4"]
[0,159.065909884965,0.42,0.069,0,1,"TNFRSF4"]
[0,33.9935155042224,0.545,0.233,0,1,"CD69"]
[0,30.5154864911136,0.643,0.156,0,1,"CD7"]
[0,16.6314407052123,0.391,0.245,0,1,"DUSP4"]
[0,15.0278789242483,0.829,0.647,0,1,"SARAF"]
[0,13.9760337136775,0.407,0.08,0,1,"TNFRSF18"]
[0,10.9018314040153,0.523,0.12,0,1,"TRBC1"]
[0,6.95517493906056,0.571,0.351,0,1,"LEPROTL1"]
[{"v":6.42703552236053e-73,"d":"6.43E-73"},119.043111407879,0.357,0.438,{"v":2.30242120553044e-68,"d":"2.30E-68"},1,"HSPA1A"]
[0.0029724206665158,26.7807264965958,0.253,0.255,1,1,"CLEC2B"]
[0,"Inf",0.324,0.146,0,2,"CCL4L2"]
[0,72.0745461109432,0.365,0.024,0,2,"IFNG"]
[0,47.4611018812548,0.364,0.04,0,2,"LAG3"]
[0,40.3311768315189,0.842,0.064,0,2,"NKG7"]
[0,14.1832022820558,0.393,0.123,0,2,"KLRB1"]
[0,10.9329994499335,0.435,0.094,0,2,"APOBEC3G"]
[0,6.7391179679074,0.339,0.107,0,2,"TBC1D10C"]
[{"v":1.06189666269943e-293,"d":"1.06E-293"},44.659285982471,0.445,0.278,{"v":3.80413860445443e-289,"d":"3.80E-289"},2,"RGS2"]
[{"v":2.61911149877283e-180,"d":"2.62E-180"},44.6633398856567,0.697,0.553,{"v":9.38270503320379e-176,"d":"9.38E-176"},2,"SRSF7"]
[{"v":2.98761641786308e-60,"d":"2.99E-60"},20.5530903833349,0.307,0.25,{"v":1.07028370553527e-55,"d":"1.07E-55"},2,"CMC1"]
[0,"Inf",0.39,0.083,0,3,"SPP1"]
[0,"Inf",0.884,0.637,0,3,"CD74"]
[0,"Inf",0.896,0.393,0,3,"HLA-DRA"]
[0,"Inf",0.837,0.23,0,3,"LYZ"]
[0,"Inf",0.667,0.16,0,3,"CCL3"]
[0,"Inf",0.475,0.126,0,3,"APOE"]
[0,"Inf",0.443,0.094,0,3,"APOC1"]
[0,"Inf",0.531,0.099,0,3,"CCL3L3"]
[0,698.286195555138,0.501,0.053,0,3,"C1QB"]
[0,498.194279912461,0.799,0.336,0,3,"HLA-DPB1"]
[0,0.828865780415801,0.156,0.508,0,4,"DDX24"]
[{"v":1.21645062356874e-287,"d":"1.22E-287"},3.06737866549017,0.173,0.329,{"v":4.35781271387264e-283,"d":"4.36E-283"},4,"CYB5A"]
[{"v":2.4060344919068e-274,"d":"2.41E-274"},28.1900059028273,0.118,0.274,{"v":8.6193779638069e-270,"d":"8.62E-270"},4,"THUMPD3-AS1"]
[0,23.950158204515,0.573,0.203,0,5,"SMIM14"]
[0,13.806032824514,0.316,0.037,0,5,"LY9"]
[0,10.4719710042984,0.888,0.282,0,5,"CD37"]
[0,7.21935530733726,0.343,0.016,0,5,"TNFRSF13B"]
[0,5.83619589654169,0.64,0.075,0,5,"CD79B"]
[0,3.58732173779844,0.599,0.018,0,5,"BANK1"]
[0,3.13372056028299,0.445,0.015,0,5,"TNFRSF13C"]
[{"v":1.98696975818064e-114,"d":"1.99E-114"},2.14771968689225,0.189,0.325,{"v":7.11812046170632e-110,"d":"7.12E-110"},5,"BUB3"]
[{"v":1.034255877064e-71,"d":"1.03E-71"},24.6474437642094,0.362,0.244,{"v":3.70511825399408e-67,"d":"3.71E-67"},5,"LCP1"]
[{"v":3.72430747834602e-19,"d":"3.72E-19"},11.0038952043264,0.277,0.226,{"v":1.33419591104268e-14,"d":"1.33E-14"},5,"CCDC50"]
[0,"Inf",0.97,0.101,0,6,"COL3A1"]
[0,"Inf",0.975,0.138,0,6,"SPARC"]
[0,"Inf",0.987,0.108,0,6,"COL1A2"]
[0,"Inf",0.659,0.116,0,6,"MGP"]
[0,"Inf",0.944,0.076,0,6,"LUM"]
[0,"Inf",0.501,0.154,0,6,"CFD"]
[0,"Inf",0.988,0.511,0,6,"CST3"]
[0,846.897073079006,0.373,0.008,0,6,"CCL11"]
[0,822.563024093137,0.555,0.022,0,6,"SFRP2"]
[0,725.459761312687,0.947,0.062,0,6,"DCN"]
[0,"Inf",0.997,0.963,0,7,"RPL34"]
[0,245.620400081087,0.829,0.077,0,7,"UBE2C"]
[0,210.541223185168,0.809,0.32,0,7,"HIST1H4C"]
[0,149.402600464317,0.999,0.787,0,7,"HMGB1"]
[0,138.859895558259,0.939,0.727,0,7,"SUB1"]
[0,128.76217645957,0.923,0.591,0,7,"CSTB"]
[0,108.56444591717,0.666,0.259,0,7,"NCOA7"]
[{"v":6.76399529162233e-281,"d":"6.76E-281"},94.1374955002071,0.339,0.134,{"v":2.42313367327078e-276,"d":"2.42E-276"},7,"EREG"]
[{"v":8.10190343142651e-40,"d":"8.10E-40"},114.776101470299,0.261,0.165,{"v":2.90242588527423e-35,"d":"2.90E-35"},7,"S100A9"]
[{"v":3.78097736369149e-6,"d":"3.78E-06"},"Inf",0.241,0.255,0.135449733076884,7,"CCL4"]
[0,294.504005130172,0.911,0.778,0,8,"SRP14"]
[0,240.872371619912,0.638,0.009,0,8,"CLDN5"]
[0,221.560096626007,0.353,0.007,0,8,"ACKR1"]
[0,177.716157997937,0.256,0.002,0,8,"SELE"]
[0,165.286578115836,0.927,0.555,0,8,"FKBP1A"]
[0,154.713896660948,0.705,0.106,0,8,"SPRY1"]
[0,152.86810585533,0.625,0.112,0,8,"SLC9A3R2"]
[0,148.982565809126,0.802,0.016,0,8,"PLVAP"]
[0,122.797366309143,0.29,0.05,0,8,"PGF"]
[0,113.257836042595,0.869,0.021,0,8,"RAMP2"]
[0,784.232997206102,0.331,0.007,0,9,"IGLV6-57"]
[0,485.152428980169,0.276,0.008,0,9,"IGKV1-12"]
[0,339.440229409032,0.997,0.694,0,9,"SSR4"]
[0,212.482583120939,0.834,0.499,0,9,"HSPA5"]
[0,202.358013357353,0.987,0.413,0,9,"XBP1"]
[0,167.307576132215,0.961,0.045,0,9,"DERL3"]
[0,141.791008335891,0.996,0.499,0,9,"HERPUD1"]
[0,140.348313766383,0.991,0.556,0,9,"HSP90B1"]
[0,134.760652014908,0.996,0.07,0,9,"MZB1"]
[0,131.692143602227,0.394,0.007,0,9,"IGLV3-1"]
[{"v":2.85169544550849e-73,"d":"2.85E-73"},5.308267655037,0.159,0.316,{"v":1.02159137639896e-68,"d":"1.02E-68"},10,"CYB5A"]
[0,3.96040624896787,0.255,0.029,0,11,"IGLC1"]
[0,2.6232997590382,0.481,0.121,0,11,"SIK3"]
[0,2.46397629579717,0.595,0.06,0,11,"RACK1"]
[0,2.30676323777426,0.342,0.021,0,11,"BICDL1"]
[0,2.09258005086363,0.441,0.116,0,11,"DENND4A"]
[0,1.91008640746878,0.329,0.045,0,11,"CDC14A"]
[0,1.89013902850411,0.354,0.101,0,11,"PDE3B"]
[0,1.78025858881353,0.356,0.058,0,11,"CAMK4"]
[0,1.75903749692867,0.394,0.103,0,11,"STAT4"]
[0,1.75530143912583,0.545,0.062,0,11,"ATP5F1E"]
[0,"Inf",0.917,0.097,0,12,"ACTA2"]
[0,409.705877305413,0.997,0.116,0,12,"CALD1"]
[0,285.634103788963,0.834,0.021,0,12,"RGS5"]
[0,109.612152594506,0.636,0.015,0,12,"MYH11"]
[0,104.844662156841,0.953,0.506,0,12,"DSTN"]
[0,97.6410622967058,0.414,0.017,0,12,"ACTG2"]
[0,96.381476803701,0.972,0.135,0,12,"MYL9"]
[0,81.2000193580445,0.846,0.033,0,12,"PPP1R14A"]
[0,63.0163724430901,0.833,0.236,0,12,"ADIRF"]
[{"v":2.64352372328197e-248,"d":"2.64E-248"},109.625308712808,0.675,0.361,{"v":9.47015938628532e-244,"d":"9.47E-244"},12,"GADD45B"]
[{"v":4.51567007130473e-34,"d":"4.52E-34"},0.454107988071296,0.187,0.321,{"v":1.61769364634421e-29,"d":"1.62E-29"},13,"PABPC4"]
[0,"Inf",0.843,0.024,0,14,"TPSB2"]
[0,"Inf",0.896,0.01,0,14,"TPSAB1"]
[0,94.546264494276,0.883,0.004,0,14,"CPA3"]
[0,63.6717080655109,0.525,0.002,0,14,"CTSG"]
[0,43.4754351076652,0.804,0.001,0,14,"MS4A2"]
[0,28.5111261799966,0.294,0.001,0,14,"ADCYAP1"]
[0,20.3602094560942,0.532,0.001,0,14,"HDC"]
[{"v":5.57323414211057e-249,"d":"5.57E-249"},26.3252540201054,0.768,0.27,{"v":1.99655539906969e-244,"d":"2.00E-244"},14,"SAMSN1"]
[{"v":1.39110671264458e-37,"d":"1.39E-37"},29.2797874110776,0.465,0.268,{"v":4.98350068737793e-33,"d":"4.98E-33"},14,"NSMCE1"]
[{"v":4.26116063212646e-36,"d":"4.26E-36"},22.2821432353981,0.295,0.133,{"v":1.52651818485298e-31,"d":"1.53E-31"},14,"ALAS1"]
[0,32.5105683616889,0.895,0.153,0,15,"GZMB"]
[0,18.1625239787833,0.753,0.016,0,15,"PLD4"]
[0,17.0432737065391,0.847,0.043,0,15,"IRF4"]
[0,16.6647691265192,0.809,0.167,0,15,"LDLRAD4"]
[0,15.1461080241922,0.783,0.002,0,15,"LILRA4"]
[0,14.2507481562068,0.707,0.071,0,15,"SLC15A4"]
[0,14.1829165548569,0.87,0.2,0,15,"IRF7"]
[{"v":1.11262830850493e-220,"d":"1.11E-220"},22.3064767654648,0.796,0.229,{"v":3.98587965238807e-216,"d":"3.99E-216"},15,"NR3C1"]
[{"v":2.93789526954234e-137,"d":"2.94E-137"},20.6792069062083,0.538,0.132,{"v":1.05247160136085e-132,"d":"1.05E-132"},15,"ATF5"]
[{"v":1.29260336213275e-94,"d":"1.29E-94"},51.2620322316055,0.686,0.26,{"v":4.63062228450436e-90,"d":"4.63E-90"},15,"LTB"]
[{"v":1.11783086236877e-8,"d":"1.12E-08"},0.478688584033168,0.301,0.171,0.000400451728134987,16,"SEPT1"]
[0.00131570902485909,2.58604660433715,0.282,0.205,1,16,"DNTTIP2"]

{"sheet":"TableS7","index":3,"n_rows":113,"n_cols":8,"rows_kept":113}
["Table-S6:Marker genes for immune cells"]
["p_val","avg_log2FC","pct.1","pct.2","p_val_adj","cluster","gene","annotation"]
[{"v":2.45683104061594e-154,"d":"2.46E-154"},4.97053526778087,0.474,0.196,{"v":8.80135151990256e-150,"d":"8.80E-150"},0,"RORA","Th"]
[{"v":1.83419917100142e-123,"d":"1.83E-123"},12.9532058763142,0.859,0.718,{"v":6.57083511019549e-119,"d":"6.57E-119"},0,"SARAF","Th"]
[{"v":9.58081453634695e-100,"d":"9.58E-100"},8.93328723915875,0.465,0.232,{"v":3.43223099950093e-95,"d":"3.43E-95"},0,"CD3G","Th"]
[{"v":4.44789531502979e-60,"d":"4.45E-60"},65.1556919991502,0.613,0.435,{"v":1.59341401765627e-55,"d":"1.59E-55"},0,"CD69","Th"]
[{"v":4.04470290304593e-45,"d":"4.04E-45"},12.508876202984,0.391,0.244,{"v":1.44897436798717e-40,"d":"1.45E-40"},0,"ITM2A","Th"]
[{"v":5.26908444192344e-26,"d":"5.27E-26"},4.30803728706783,0.403,0.299,{"v":1.88759681047465e-21,"d":"1.89E-21"},0,"NR3C1","Th"]
[{"v":3.93834657457098e-16,"d":"3.94E-16"},6.8658730613674,0.108,0.181,{"v":1.41087327687431e-11,"d":"1.41E-11"},0,"FKBP4","Th"]
[{"v":1.19192126017882e-7,"d":"1.19E-07"},3.93720189010264,0.175,0.131,0.00426993872246459,0,"SH2D1A","Th"]
[{"v":1.20253462225785e-5,"d":"1.20E-05"},6.64664343322058,0.381,0.348,0.430796003077653,0,"FAM177A1","Th"]
[0.00633603131360017,4.92925477553059,0.137,0.161,1,0,"CTD-3252C9.4","Th"]
[0,"Inf",0.428,0.044,0,1,"SPP1","TAM"]
[0,"Inf",0.942,0.764,0,1,"CD74","TAM"]
[0,"Inf",0.997,0.969,0,1,"FTH1","TAM"]
[0,"Inf",0.276,0.016,0,1,"MMP12","TAM"]
[0,"Inf",0.518,0.07,0,1,"APOE","TAM"]
[0,"Inf",0.996,0.946,0,1,"FTL","TAM"]
[0,"Inf",0.894,0.141,0,1,"CST3","TAM"]
[0,"Inf",0.387,0.024,0,1,"MMP9","TAM"]
[{"v":3.62915686681729e-301,"d":"3.63E-301"},"Inf",0.984,0.95,{"v":1.30010915596862e-296,"d":"1.30E-296"},1,"ACTB","TAM"]
[{"v":1.50066584453497e-294,"d":"1.50E-294"},"Inf",0.233,0.017,{"v":5.37598532146209e-290,"d":"5.38E-290"},1,"CCL18","TAM"]
[{"v":2.5810269850211e-241,"d":"2.58E-241"},"Inf",0.986,0.993,{"v":9.24627107113959e-237,"d":"9.25E-237"},1,"MT-CO1","TAM"]
[0,1.38576305207301,0.498,0.08,0,2,"GZMK","Teff"]
[{"v":1.27923986614474e-27,"d":"1.28E-27"},1.19159456369447,0.115,0.043,{"v":4.58274889647691e-23,"d":"4.58E-23"},2,"KLRG1","Teff"]
[{"v":1.92063006053237e-27,"d":"1.92E-27"},0.987460706247139,0.232,0.123,{"v":6.88046512885116e-23,"d":"6.88E-23"},2,"LYAR","Teff"]
[{"v":9.34516264262392e-21,"d":"9.35E-21"},17.7211917006473,0.527,0.624,{"v":3.34781106509359e-16,"d":"3.35E-16"},2,"SOD1","Teff"]
[{"v":4.54684697515574e-19,"d":"4.55E-19"},4.87836829764782,0.089,0.192,{"v":1.62886246037979e-14,"d":"1.63E-14"},2,"SELL","Teff"]
[{"v":1.67853150237224e-12,"d":"1.68E-12"},8.54526968078524,0.379,0.287,{"v":6.0131712540983e-8,"d":"6.01E-08"},2,"TUBA4A","Teff"]
[{"v":4.04067288357104e-10,"d":"4.04E-10"},0.845959289283436,0.163,0.104,{"v":1.44753065381049e-5,"d":"1.45E-05"},2,"PYHIN1","Teff"]
[{"v":7.08892729693593e-7,"d":"7.09E-07"},9.87814890825642,0.074,0.122,0.0253953731485433,2,"AQP3","Teff"]
[{"v":3.97933811458599e-6,"d":"3.98E-06"},7.53872044206962,0.078,0.122,0.142555808616928,2,"FABP1","Teff"]
[{"v":7.90357644697532e-5,"d":"7.90E-05"},0.97195606745689,0.139,0.185,1,2,"INTS6","Teff"]
[0,43.4580172754415,0.789,0.01,0,3,"MS4A1","B"]
[0,26.0236023650528,0.642,0.114,0,3,"CD79B","B"]
[0,25.2642481995429,0.558,0.083,0,3,"SMIM14","B"]
[{"v":3.54503106598136e-55,"d":"3.55E-55"},17.1397271925163,0.587,0.368,{"v":1.26997192907716e-50,"d":"1.27E-50"},3,"LIMD2","B"]
[{"v":1.50377903069867e-49,"d":"1.50E-49"},21.9549270501978,0.169,0.404,{"v":5.38713799957492e-45,"d":"5.39E-45"},3,"ABRACL","B"]
[{"v":5.22873481148904e-22,"d":"5.23E-22"},26.1451309381869,0.77,0.644,{"v":1.87314195886783e-17,"d":"1.87E-17"},3,"CORO1A","B"]
[{"v":4.07342347965221e-17,"d":"4.07E-17"},33.8003884421228,0.518,0.391,{"v":1.45926322735061e-12,"d":"1.46E-12"},3,"RPL22L1","B"]
[{"v":5.55159141587894e-12,"d":"5.55E-12"},27.5784981582551,0.66,0.576,{"v":1.98880210882447e-7,"d":"1.99E-07"},3,"HMGN1","B"]
[{"v":1.1311317658694e-9,"d":"1.13E-09"},16.850548949196,0.625,0.531,{"v":4.05216643805055e-5,"d":"4.05E-05"},3,"EIF3H","B"]
[{"v":9.28898819394942e-8,"d":"9.29E-08"},21.1182334528316,0.285,0.365,0.00332768713060044,3,"PRDX6","B"]
[0,317.685476759157,0.55,0.1,0,4,"GNLY","Tex"]
[0,130.13362918626,0.898,0.198,0,4,"GZMA","Tex"]
[0,49.3441991538121,0.808,0.138,0,4,"GZMB","Tex"]
[0,46.4534205420574,0.479,0.07,0,4,"IFNG","Tex"]
[0,43.5730419774618,0.965,0.189,0,4,"NKG7","Tex"]
[0,39.69406899031,0.979,0.278,0,4,"CCL5","Tex"]
[{"v":3.42867312848883e-219,"d":"3.43E-219"},55.0168920962415,0.238,0.023,{"v":1.22828786154984e-214,"d":"1.23E-214"},4,"XCL2","Tex"]
[{"v":1.59481394593172e-51,"d":"1.59E-51"},46.4588090720315,0.939,0.825,{"v":5.71326147990578e-47,"d":"5.71E-47"},4,"UBB","Tex"]
[{"v":3.33696556301267e-6,"d":"3.34E-06"},24.80666653818,0.451,0.376,0.119543454329366,4,"DDIT4","Tex"]
[0.000562409457931778,28.5272877137162,0.076,0.112,1,4,"MYC","Tex"]
[0,"Inf",0.688,0.14,0,5,"IGHA2","Plasma"]
[0,"Inf",0.544,0.047,0,5,"IGHG2","Plasma"]
[0,"Inf",0.437,0.022,0,5,"IGHGP","Plasma"]
[0,888.869721431572,0.325,0.006,0,5,"IGLV6-57","Plasma"]
[0,647.198348388072,0.213,0.006,0,5,"IGLL5","Plasma"]
[0,387.441394489399,1,0.626,0,5,"SSR4","Plasma"]
[0,358.364391926627,0.997,0.083,0,5,"MZB1","Plasma"]
[0,305.279542065545,0.983,0.411,0,5,"HSP90B1","Plasma"]
[{"v":2.32245849108576e-164,"d":"2.32E-164"},"Inf",0.248,0.029,{"v":8.31997529846562e-160,"d":"8.32E-160"},5,"IGLC7","Plasma"]
[{"v":8.79016819519275e-139,"d":"8.79E-139"},253.664576879262,0.113,0.005,{"v":3.14898985424585e-134,"d":"3.15E-134"},5,"IGKV1-5","Plasma"]
[0,83.1730034913003,0.781,0.149,0,6,"TNFRSF4","Treg"]
[0,13.971639926721,0.593,0.083,0,6,"IL2RA","Treg"]
[0,13.6413423719523,0.601,0.077,0,6,"AC133644.2","Treg"]
[{"v":3.72376518739957e-284,"d":"3.72E-284"},15.4143410340956,0.983,0.565,{"v":1.33400164073402e-279,"d":"1.33E-279"},6,"IL32","Treg"]
[{"v":2.52832680562264e-201,"d":"2.53E-201"},17.9442639612748,0.153,0.005,{"v":9.05747794846254e-197,"d":"9.06E-197"},6,"CD177","Treg"]
[{"v":1.5063057908967e-196,"d":"1.51E-196"},16.92067575903,0.598,0.148,{"v":5.39618986530833e-192,"d":"5.40E-192"},6,"ICOS","Treg"]
[{"v":2.7018077330385e-192,"d":"2.70E-192"},13.871441858895,0.895,0.408,{"v":9.67895602283711e-188,"d":"9.68E-188"},6,"CD2","Treg"]
[{"v":9.49253058787778e-165,"d":"9.49E-165"},14.4838976315439,0.947,0.472,{"v":3.40060415780133e-160,"d":"3.40E-160"},6,"CD3D","Treg"]
[{"v":3.12192512334397e-71,"d":"3.12E-71"},21.037827066336,0.923,0.649,{"v":1.11839845618674e-66,"d":"1.12E-66"},6,"RGS1","Treg"]
[0.000760083524808592,18.5304640158433,0.169,0.124,1,6,"GPR171","Treg"]
[0,3.33555257484785,0.832,0.092,0,7,"SIK3","unknown"]
[0,2.94772001079963,0.707,0.008,0,7,"BICDL1","unknown"]
[0,2.7493953590283,0.768,0.031,0,7,"RACK1","unknown"]
[0,2.71749989180653,0.368,0.003,0,7,"AL136456.1","unknown"]
[{"v":9.90113044480506e-284,"d":"9.90E-284"},2.85385579125606,0.709,0.112,{"v":3.54698097054697e-279,"d":"3.55E-279"},7,"PDE3B","unknown"]
[{"v":3.1442942562955e-143,"d":"3.14E-143"},5.59618079067535,0.547,0.111,{"v":1.1264119743753e-138,"d":"1.13E-138"},7,"SMARCA2","unknown"]
[{"v":3.56222207899416e-58,"d":"3.56E-58"},5.14756046030879,0.741,0.358,{"v":1.27613043757887e-53,"d":"1.28E-53"},7,"PPP1CB","unknown"]
[{"v":1.36694860758895e-32,"d":"1.37E-32"},3.43634040309443,0.453,0.194,{"v":4.89695669182665e-28,"d":"4.90E-28"},7,"VPS37B","unknown"]
[{"v":1.17930533143611e-30,"d":"1.18E-30"},8.8390581233116,0.232,0.069,{"v":4.22474341933671e-26,"d":"4.22E-26"},7,"ICA1","unknown"]
[0.000234561144323687,6.15666088267473,0.285,0.188,1,7,"C12orf75","unknown"]
[0,1.84128484182957,0.42,0.017,0,8,"TXNDC5","unknown"]
[{"v":6.28299612014608e-294,"d":"6.28E-294"},6.98821011347783,0.392,0.017,{"v":2.25082053008113e-289,"d":"2.25E-289"},8,"IGLC1","unknown"]
[{"v":1.82274186991968e-153,"d":"1.82E-153"},1.61463158927131,0.314,0.024,{"v":6.52979047480028e-149,"d":"6.53E-149"},8,"TEX14","unknown"]
[{"v":5.22952224751288e-114,"d":"5.23E-114"},1.71985918426923,0.345,0.039,{"v":1.87342404994902e-109,"d":"1.87E-109"},8,"CYTOR","unknown"]
[{"v":8.91443322292091e-92,"d":"8.91E-92"},1.67382832979482,0.408,0.07,{"v":3.19350655777919e-87,"d":"3.19E-87"},8,"EIF2AK3","unknown"]
[{"v":1.85539840009776e-72,"d":"1.86E-72"},2.05549260995217,0.412,0.08,{"v":6.6467792285102e-68,"d":"6.65E-68"},8,"TP53INP1","unknown"]
[{"v":8.96212373507738e-62,"d":"8.96E-62"},1.50183381777902,0.4,0.089,{"v":3.21059120685412e-57,"d":"3.21E-57"},8,"HIPK2","unknown"]
[{"v":8.94345062616974e-58,"d":"8.94E-58"},1.64650378452179,0.447,0.123,{"v":3.20390175231905e-53,"d":"3.20E-53"},8,"FNDC3A","unknown"]
[{"v":2.85636191461957e-41,"d":"2.86E-41"},1.86638344411407,0.42,0.136,{"v":1.02326309229332e-36,"d":"1.02E-36"},8,"UBE2H","unknown"]
[{"v":1.65592666927882e-30,"d":"1.66E-30"},3.28689887878689,0.31,0.089,{"v":5.93219170002444e-26,"d":"5.93E-26"},8,"TMEM156","unknown"]
[0,4.8603073187489,0.752,0.047,0,9,"DOCK4","MDSC"]
[0,4.75983656493492,0.54,0.015,0,9,"AZIN1-AS1","MDSC"]
[0,4.00092668526475,0.733,0.035,0,9,"LUCAT1","MDSC"]
[0,3.9418213003719,0.822,0.069,0,9,"AQP9","MDSC"]
[{"v":6.67023045924395e-302,"d":"6.67E-302"},4.32817858725639,0.802,0.082,{"v":2.38954335971955e-297,"d":"2.39E-297"},9,"ARHGAP26","MDSC"]
[{"v":3.8948311997572e-245,"d":"3.89E-245"},4.29308418256589,0.312,0.011,{"v":1.39528432900102e-240,"d":"1.40E-240"},9,"CCL3L1","MDSC"]
[{"v":7.41608906282331e-224,"d":"7.42E-224"},9.34989867954937,0.351,0.016,{"v":2.65673974586582e-219,"d":"2.66E-219"},9,"HCAR2","MDSC"]
[{"v":5.69177887140324e-173,"d":"5.69E-173"},36.3164462034704,0.332,0.02,{"v":2.03902286289149e-168,"d":"2.04E-168"},9,"HCAR3","MDSC"]
[{"v":1.78188665818311e-12,"d":"1.78E-12"},9.35239061395482,0.188,0.069,{"v":6.38343076427516e-8,"d":"6.38E-08"},9,"NSMAF","MDSC"]
[{"v":3.56681203022152e-6,"d":"3.57E-06"},28.5408778129746,0.198,0.408,0.127777474170656,9,"RHOH","MDSC"]
[{"v":2.70172847290817e-88,"d":"2.70E-88"},19.2235776505641,0.646,0.086,{"v":9.67867208134622e-84,"d":"9.68E-84"},10,"DNAJB4","unknown"]
[{"v":2.09662316135215e-79,"d":"2.10E-79"},110.562851947239,1,0.35,{"v":7.51094281322794e-75,"d":"7.51E-75"},10,"HSPA1B","unknown"]
[{"v":8.17529620890046e-73,"d":"8.18E-73"},93.2505355518309,1,0.427,{"v":2.9287181138765e-68,"d":"2.93E-68"},10,"HSPA1A","unknown"]
[{"v":5.20964565550602e-64,"d":"5.21E-64"},19.6000436412005,0.948,0.359,{"v":1.86630345962848e-59,"d":"1.87E-59"},10,"CACYBP","unknown"]
[{"v":1.37044981742749e-35,"d":"1.37E-35"},18.2111507807471,0.458,0.095,{"v":4.90949942595224e-31,"d":"4.91E-31"},10,"GADD45G","unknown"]
[{"v":1.46062420989937e-33,"d":"1.46E-33"},16.0507620194526,0.698,0.25,{"v":5.23254016954351e-29,"d":"5.23E-29"},10,"MRPL18","unknown"]
[{"v":4.05626686102158e-8,"d":"4.06E-08"},88.8601060139615,0.26,0.097,0.00145311704029237,10,"MAGEH1","unknown"]
[{"v":4.98495617354271e-8,"d":"4.98E-08"},14.3600453220287,0.156,0.043,0.00178581069960994,10,"TNFSF9","unknown"]
[{"v":2.2359722042036e-5,"d":"2.24E-05"},26.8865636709342,0.656,0.54,0.801014682433896,10,"SAP18","unknown"]
[0.000431054849565541,15.0909143738816,0.51,0.374,1,10,"STK17A","unknown"]

{"sheet":"TableS8","index":4,"n_rows":28,"n_cols":2,"rows_kept":28}
["Table-S8:Marker genes for T cells state"]
["Pro inflammatory","Anti-inflammatory"]
["IL1A","TIGIT"]
["IL1B","IDO1"]
["TNF","LGALS3"]
["IFNG","PDCD1"]
["TBX21","FOXP3"]
["CCL3","ENTPD1"]
["CCL4","CD274"]
["PRF1","CSF2"]
["GZMA","CTLA4"]
["GZMB","CXCL12"]
["GZMK","CXCL5"]
["GZMH","IL8"]
["CD8A","MIF"]
["FASLG","PTGS2"]
["CCL2","VEGFA"]
["CCL20"]
["IL2"]
["IL6"]
["IL12a"]
["IL17a"]
["IL23a"]
["PTGS2"]
["TLR4"]
["TNF"]
["Pro_inflammatory",29961579]
["Anti_inflammatory",29961579]