|  | SWISS-MODEL Homology Modelling Report

## Model Building Report

This document lists the results for the homology modelling project "4_1_Oct_SF_Bin14_scaffold_2633_c1_666-4172_1" submitted to SWISS-MODEL workspace on March 29, 2023, 10:15 p.m..The submitted primary amino acid sequence is given in Table T1.

If you use any results in your research, please cite the relevant publications:

- Waterhouse, A., Bertoni, M., Bienert, S., Studer, G., Tauriello, G., Gumienny, R., Heer, F.T., de Beer, T.A.P., Rempfer, C., Bordoli, L., Lepore, R., Schwede, T. SWISS-MODEL: homology modelling of protein structures and complexes. Nucleic Acids Res. 46(W1), W296-W303 (2018).
- Bienert, S., Waterhouse, A., de Beer, T.A.P., Tauriello, G., Studer, G., Bordoli, L., Schwede, T. The SWISS-MODEL Repository - new features and functionality. Nucleic Acids Res. 45, D313-D319 (2017).
- Studer, G., Tauriello, G., Bienert, S., Biasini, M., Johner, N., Schwede, T. ProMod3 - A versatile homology modelling toolbox. PLOS Comp. Biol. 17(1), e1008667 (2021).
- Studer, G., Rempfer, C., Waterhouse, A.M., Gumienny, G., Haas, J., Schwede, T. QMEANDisCo - distance constraints applied on model quality estimation. Bioinformatics 36, 1765-1771 (2020).
- Bertoni, M., Kiefer, F., Biasini, M., Bordoli, L., Schwede, T. Modeling protein quaternary structure of homo- and hetero-oligomers beyond binary interactions by homology. Scientific Reports 7 (2017).

## Results

The SWISS-MODEL template library (SMTL version 2023-03-23, PDB release 2023-03-17) was searched with for evolutionary related structures matching the target sequence in Table T1. For details on the template search, see Materials and Methods. Overall 513 templates were found (Table T2).

## Models

The following models were built (see Materials and Methods "Model Building"):

### Model #01 | File | Built with | Oligo-State | Ligands | GMQE | QMEANDisCo Global
--- | --- | --- | --- | --- | --- | ---
| PDB | ProMod3 3.2.1 | monomer | 1 x MO: MOLYBDENUM ATOM; | 0.70 | 0.71 ± 0.05

Template | Seq Identity | Oligo-state | QSQE | Found by | Method | Resolution | Seq Similarity | Range | Coverage | Description
--- | --- | --- | --- | --- | --- | --- | --- | --- | --- | ---
7b04.1.B | 40.77 | monomer | 0.00 | BLAST | X-ray | 2.97Å | 0.41 | 28 - 1160 | 0.96 | Nitrite oxidoreductase subunit A

### Included Ligands

Ligand | Description
--- | ---
1 x MO | MOLYBDENUM ATOM

### Excluded ligands

Ligand Name.Number | Reason for Exclusion | Description
--- | --- | ---
CA.10 | Binding site not conserved. | CALCIUM ION
CA.11 | Binding site not conserved. | CALCIUM ION
F3S.4 | Binding site not conserved. | FE3-S4 CLUSTER
HEM.9 | Binding site not conserved. | PROTOPORPHYRIN IX CONTAINING FE
MD1.5 | Binding site not conserved. | PHOSPHORIC ACID 4-(2-AMINO-4-OXO-3,4,5,6,-TETRAHYDRO-PTERIDIN-6-YL)-2-HYDROXY-3,4-DIMERCAPTO-BUT-3-EN-YL ESTER GUANYLATE ESTER
MD1.6 | Binding site not conserved. | PHOSPHORIC ACID 4-(2-AMINO-4-OXO-3,4,5,6,-TETRAHYDRO-PTERIDIN-6-YL)-2-HYDROXY-3,4-DIMERCAPTO-BUT-3-EN-YL ESTER GUANYLATE ESTER
SF4.1 | Binding site not conserved. | IRON/SULFUR CLUSTER
SF4.2 | Binding site not conserved. | IRON/SULFUR CLUSTER
SF4.3 | Binding site not conserved. | IRON/SULFUR CLUSTER
SF4.8 | Binding site not conserved. | IRON/SULFUR CLUSTER

    Target    SDLSRRELLKRAVVVGTGAGLAELFLPAQFLSSASAQSEPQAVAIANPLAQMPDRSWERIYRDQFAEEDSFVFTCAPNDT
    7b04.1.B  --LTRRAFLQVAGATGATLTLAKNAMAFRLLKPA--------VVVDNPLDTYPDRRWESVYRDQYQYDRTFTYCCSPNDT

    Target    HNCLLRAHVKNGVIVRISPTYGYGKATDLAGNQASHRWDPRICQKGLILGRRIYGDRRVKAPMIRKGFKEWADAGFPRHD
    7b04.1.B  HACRIRAFVRNNVMMRVEQNYDHQNYSDLYGNKATRNWNPRMCLKGYTFHRRVYGPYRLRYPLIRKGWKRWADDGFPELT

    Target    -DGTPRADMEKRGYDEWLQIPWDEALAIAAKTLQNVAETYKGEDGAGKLLEQGYEPAMVEAMHGAGVQAIKMRGGMPLLG
    7b04.1.B  PENKTKYMFDNRGNDELLRASWDEAFTYASKGIIHITKKYSGPEGAQKLIDQGYPKEMVDRMQGAGTRTFKGRGGMGLLG

    Target    AGRVFGFYRFANMLALLDGKLRPEAPPEEIVGSRAFDNYAWHTDLPPGHPMVSGSQTVDFDLFAAEHSKLLVLIGMNWIC
    7b04.1.B  VIGKYGMYRFNNCLAIVDAHNRGVGP-DQALGGRNWSNYTWHGDQAPGHPFSHGLQTSDVDMNDVRFSKLLIQTGKNLIE

    Target    TKMPDAHWIGDARLKGTRVVVISADYMPTANKADEIVILRPGTDTAFLLGVARELITKKLYDRDAVIQRTDLPLLVRLDT
    7b04.1.B  NKMPEAHWVTEVMERGGKIVVITPEYSPSAQKADYWIPIRNNTDTALFLGITKILIDNKWYDADYVKKFTDFPLLIRTDT

    Target    GERLSARDVFEGYRQAPLENYVALKTEEELAAPPSPPFTADKQVVPTELREEWGDFVYWDRATNGPAAVNRDEIG---AK
    7b04.1.B  LKRVSPKDIIPNYKL------------QDISDGPSYHI----QGLKDEQREIIGDFVVWDAKSKGPKAITRDDVGETLVK

    Target    FAGDPALLGAFDVTLVDGTNVKARTAFSLLKEYLDENFDVQTTSEVCNVDPAAVRSLARQLAANKGNALLAAGMGPNHYF
    7b04.1.B  KGIDPVLEGSFKLKTIDGKEIEVMTLLEMYKIHL-RDYDIDSVVSMTNSPKDLIERLAKDIATIKPVAIHYGE-GVNHYF

    Target    NADLFGRVHFLVAALTDNIGHFSGNVGSYAGNYRGSLFQA-------MGQWIAENPFDQEADLTKPAR---VKRYFKSES
    7b04.1.B  HATLMNRSYYLPVMLTGNVGYFGSGSHTWAGNYKAGNFQASKWSGPGFYGWVAEDVFKPNLDPYASAKDLNIKGRALDEE

    Target    AHYWNYGDRPLVSPS-----EIITGKSHMPTPTKLIWFGNSNSLLGNAKWSFDVVKNTLPKQDAVFCNEWHWTSSCEYSD
    7b04.1.B  VAYWNHSERPLIVNTPKYGRKVFTGKTHMPSPTKVLWFTNVN-LINNAKHVYQMLKNVNPNIEQIMSTDIEITGSIEYAD

    Target    LVFPADSWAEFKLPDMTASCTNPFLLAFPKTPLARIHNTRSDYEILAGVAAALADLVDEPRMKTYWKGILDGDPTPYLQR
    7b04.1.B  FAFPANSWVEFQEFEITNSCSNPFIQIWGKTGITPVYESKDDVKILAGMASKLGELLRDKRFEDNWKFAIEGRASVYINR

    Target    VLSGSNATRGILYEDLHASS--AKGVPLLMNARTYPRHAGWEQRQEDKPWYTPTGRLEFYRPEPEWQAAGESLPIWREPV
    7b04.1.B  LLDGSTTMKGYTCEDILNGKYGEPGVAMLL-FRTYPRHPFWEQVHESLPFYTPTGRLQAYNDEPEIIEYGENFIVHREGP

    Target    DATFYEPNAILANSKHPSINPRAPEDYGVPESQMDVETRQYRNVVRTWQELKLSKHPLTEKDPAYRFVFQTPKYRWGAHS
    7b04.1.B  EATPYLPNAIV--STNPYIR---PDDYGIPENAEYWEDRTVRNIKKSWEETKKTKNFLWEK--GYHFYCVTPKSRHTVHS

    Target    TAVDSDWIAMLFGPFGDPYRRDSRTPWTGEAYAEINPRDAKELGLKDGDYIWLDADPEDRPYRGADSSDEFYDVARAMMR
    7b04.1.B  QWAVTDWNFIWNNNFGDPYRMDKRMPGVGEHQIHIHPQAARDLGIEDGDYVYVDANPADRPYEGWKPNDSFYKVSRLMLR

    Target    VRIYSGMPRRVIRTWFNMYAATPGTVQAQKDVPGGPAQNQDTGYVALFRHGSHQSGTRAYLRPTQMTDSMNRKAYFGQTI
    7b04.1.B  AKYNPAYPYNCTMMKHSAWISSDKTVQAHETRPDGRALSP-SGYQSSFRYGSQQSITRDWSMPMHQLDSLFHKAKIGMKF

    Target    GKGFEADVHSPSGAPKEGYVKVEKAEDGGDEGVGEWRPVTLGLRPDDPSEAMQAYLAGEFVTRKRKGS
    7b04.1.B  IFGFEADNHCINTVPKETLVKITKAENGGMGGKGVWDPVKTGYTAGNENDFMKKFLNGELI-------

### Model #02 | File | Built with | Oligo-State | Ligands | GMQE | QMEANDisCo Global
--- | --- | --- | --- | --- | --- | ---
| PDB | ProMod3 3.2.1 | monomer | None | 0.41 | 0.51 ± 0.05

Template | Seq Identity | Oligo-state | QSQE | Found by | Method | Resolution | Seq Similarity | Range | Coverage | Description
--- | --- | --- | --- | --- | --- | --- | --- | --- | --- | ---
3ir5.1.A | 24.12 | monomer | 0.00 | HHblits | X-ray | 2.30Å | 0.32 | 54 - 1130 | 0.78 | Respiratory nitrate reductase 1 alpha chain

### Excluded ligands

Ligand Name.Number | Reason for Exclusion | Description
--- | --- | ---
6MO.3 | Clashing with protein. | MOLYBDENUM(VI) ION
AGA.5 | Binding site not conserved. | (1S)-2-{[{[(2S)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PENTANOYLOXY)METHYL]ETHYL OCTANOATE
F3S.9 | Binding site not conserved. | FE3-S4 CLUSTER
HEM.10 | Binding site not conserved. | PROTOPORPHYRIN IX CONTAINING FE
HEM.11 | Binding site not conserved. | PROTOPORPHYRIN IX CONTAINING FE
MD1.1 | Binding site not conserved. | PHOSPHORIC ACID 4-(2-AMINO-4-OXO-3,4,5,6,-TETRAHYDRO-PTERIDIN-6-YL)-2-HYDROXY-3,4-DIMERCAPTO-BUT-3-EN-YL ESTER GUANYLATE ESTER
MD1.2 | Binding site not conserved. | PHOSPHORIC ACID 4-(2-AMINO-4-OXO-3,4,5,6,-TETRAHYDRO-PTERIDIN-6-YL)-2-HYDROXY-3,4-DIMERCAPTO-BUT-3-EN-YL ESTER GUANYLATE ESTER
SF4.4 | Binding site not conserved. | IRON/SULFUR CLUSTER
SF4.6 | Binding site not conserved. | IRON/SULFUR CLUSTER
SF4.7 | Binding site not conserved. | IRON/SULFUR CLUSTER
SF4.8 | Binding site not conserved. | IRON/SULFUR CLUSTER

    Target    SDLSRRELLKRAVVVGTGAGLAELFLPAQFLSSASAQSEPQAVAIANPLAQMPDRSWERIYRDQFAEEDSFVFTCAPNDT
    3ir5.1.A  -----------------------------------------------------NRDWEDGYRQRWQHDKIVRSTCGVNCT

    Target    HNCLLRAHVKNGVIVRISPTYGYGKATDLAGNQASHRWDPRICQKGLILGRRIYGDRRVKAPMIRKGFKE-WADAGFP--
    3ir5.1.A  GSCSWKIYVKNGLVTWETQQTDYPR-----TRPDLPNHEPRGCPRGASYSWYLYSANRLKYPMMRKRLMKMWREAKALHS

    Target    -------R-HD-DGTPRADMEKRGYDEWLQIPWDEALAIAAKTLQNVAETYKGEDGAGKLLEQGYEPAMVEAMHGAGVQA
    3ir5.1.A  DPVEAWASIIEDADKAKSFKQARGRGGFVRSSWQEVNELIAASNVYTIKNYGPDR----VAG----------FSPIPAMS

    Target    IKMRGGMPLLGAGRVFGFYRFANMLALLDGKLRPEAPPEEIVGSRAFDNYAWHTDLPPGHPMVSGSQTVDFDLFAAEHSK
    3ir5.1.A  M-----------VSYASGARYLS-----------------LIGGTCLSFYDWYCDLPPASPQTWGEQTDVPESADWYNSS

    Target    LLVLIGMNWICTKMPDAHWIGDARLKGTRVVVISADYMPTANKADEIVILRPGTDTAFLLGVARELITKKL------YDR
    3ir5.1.A  YIIAWGSNVPQTRTPDAHFFTEVRYKGTKTVAVTPDYAEIAKLCDLWLAPKQGTDAAMALAMGHVMLREFHLDNPSQYFT

    Target    DAVIQRTDLPLLVRLD-------TGERLSARDVFEGYRQAPL--ENYVALKTEEELAAPPSPPFTADKQVVPT-ELREEW
    3ir5.1.A  DYVRRYTDMPMLVMLEERDGYYAAGRMLRAADLVDALGQENNPEWKTVAFNT-------------NGEMVAPNGSIGFRW

    Target    GDFVYWDR-----ATNGPAAVNR------DE----IGAKFA-----------GDPALLG---AFDVTLVDGTNVKARTAF
    3ir5.1.A  GEKGKWNLEQRDGKTGEETELQLSLLGSQDEIAEVGFPYFGGDGTEHFNKVELENVLLHKLPVKRLQLADGSTALVTTVY

    Target    SLLK------------------EYLDENFDVQTTSEVCNVDPAAVRSLARQLAANK----GNALLAAGMGPNHYFNADLF
    3ir5.1.A  DLTLANYGLERGLNDVNCATSYDDV-KAYTPAWAEQITGVSRSQIIRIAREFADNADKTHGRSMIIVGAGLNHWYHLDMN

    Target    GRVHFLVAALTDNIGHFSGNVGSYAGNYRGSLFQAMGQ--------------------------WIAENPFDQEADLTKP
    3ir5.1.A  YRGLINMLIFCGCVGQSGGGWAHYVGQEKLRPQTGWQPLAFALDWQRPARHMNSTSYFYNHSSQWRYETVTAEE--LLSP

    Target    A-RVKRYFK--------SESAHYW----NYGDRPL----------V-----SPSEIITGKS--------HMPTPTKLIWF
    3ir5.1.A  MADKSRYTGHLIDFNVRAERMGWLPSAPQLGTNPLTIAGEAEKAGMNPVDYTVKSLKEGSIRFAAEQPENGKNHPRNLFI

    Target    GNSNSLLGNAKWSFDV------------------------------VKNTLPKQDAVFCNEWHWTSSCEYSDLVFPADSW
    3ir5.1.A  WRSNLLGSSGKGHEFMLKYLLGTEHGIQGKDLGQQGGVKPEEVDWQDNGLEGKLDLVVTLDFRLSSTCLYSDIILPTATW

    Target    AEFKLPDMTASCTNPFLLAFPKTPLARIHNTRSDYEILAGVAAALADLVDEP------------------------RMKT
    3ir5.1.A  YEK--DDMNTSDMHPFIHPLSA-AVDPAWEAKSDWEIYKAIAKKFSEVCVGHLGKETDIVTLPIQHDSAAELAQPLDVKD

    Target    YWKGILD---G------------------------------------------DPTPYLQ--------------------
    3ir5.1.A  WKKGECDLIPGKTAPHIMVVERDYPATYERFTSIGPLMEKIGNGGKGIAWNTQSEMDLLRKLNYTKAEGPAKGQPMLNTA

    Target    -----RVLSGSNATRGI----LYEDLHASSA-----------KGVPLLMNA------------------RTYPRHAGWEQ
    3ir5.1.A  IDAAEMILTLAPETNGQVAVKAWAALSEFTGRDHTHLALNKEDEKIRFRDIQAQPRKIISSPTWSGLEDEHVSYNAGYTN

    Target    RQEDKPWYTPTGRLEFYRPEPEWQAAGESLPIWREPVDATFYEPNAILANSKHPSINPRAPEDYGVPESQMDVETRQYRN
    3ir5.1.A  VHELIPWRTLSGRQQLYQDHQWMRDFGESLLVYRPPIDTRSVKE-------------------V----------------

    Target    VVRTWQELKLSKHPLTEKDPAYRFVFQTPKYRWGAHSTAVDSDWIAMLFGPFGDPYRRDSRTPWTGEAYAEINPRDAKEL
    3ir5.1.A  -----I------GQKSNGNQEKALNFLTPHQKWGIHSTYSDNLLMLTLG---------------RGGPVVWLSEADAKDL

    Target    GLKDGDYIWLDADPEDRPYRGADSSDEFYDVARAMMRVRIYSGMPRRVIRTWFNMYAATPGTVQAQKDVPGGPAQNQDTG
    3ir5.1.A  GIADNDWIEVFNS-----------------NGALTARAVVSQRVPAGMTMMYHAQERIVN--------LPGSEI------

    Target    YVALFRHGSHQSGTRAYLRPTQMTDSMNRKAYFGQTIGKGFEADVHSPSGAPKEGYVKVEKAEDGGDEGVGEWRPVTLGL
    3ir5.1.A  --TQQRGGIHNSVTRITPKPTHMIGGYAHLAY-------G--FNYYGTVGSNRDEFVVVRKMKNIDWL------------

    Target    RPDDPSEAMQAYLAGEFVTRKRKGS
    3ir5.1.A  -------------------------

### Model #03 | File | Built with | Oligo-State | Ligands | GMQE | QMEANDisCo Global
--- | --- | --- | --- | --- | --- | ---
| PDB | ProMod3 3.2.1 | monomer | None | 0.27 | 0.47 ± 0.05

Template | Seq Identity | Oligo-state | QSQE | Found by | Method | Resolution | Seq Similarity | Range | Coverage | Description
--- | --- | --- | --- | --- | --- | --- | --- | --- | --- | ---
1h0h.1.A | 17.09 | monomer | 0.00 | HHblits | X-ray | 1.80Å | 0.28 | 69 - 756 | 0.47 | FORMATE DEHYDROGENASE SUBUNIT ALPHA

### Excluded ligands

Ligand Name.Number | Reason for Exclusion | Description
--- | --- | ---
2MD.2 | Binding site not conserved. | GUANYLATE-O'-PHOSPHORIC ACID MONO-(2-AMINO-5,6-DIMERCAPTO-4-OXO-3,5,6,7,8A,9,10,10A-OCTAHYDRO-4H-8-OXA-1,3,9,10-TETRAAZA-ANTHRACEN-7-YLMETHYL) ESTER
CA.6 | Binding site not conserved. | CALCIUM ION
EPE.7 | Not biologically relevant. | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID
MGD.3 | Binding site not conserved. | 2-AMINO-5,6-DIMERCAPTO-7-METHYL-3,7,8A,9-TETRAHYDRO-8-OXA-1,3,9,10-TETRAAZA-ANTHRACEN-4-ONE GUANOSINE DINUCLEOTIDE
SF4.5 | Binding site not conserved. | IRON/SULFUR CLUSTER
SF4.8 | Binding site not conserved. | IRON/SULFUR CLUSTER
SF4.9 | Binding site not conserved. | IRON/SULFUR CLUSTER
SF4.10 | Binding site not conserved. | IRON/SULFUR CLUSTER
UNX.4 | Not biologically relevant. | UNKNOWN ATOM OR ION
W.1 | Not in contact with model. | TUNGSTEN ION

    Target    SDLSRRELLKRAVVVGTGAGLAELFLPAQFLSSASAQSEPQAVAIANPLAQMPDRSWERIYRDQFAEEDSFVFTCAPNDT
    1h0h.1.A  --------------------------------------------------------------------AKQTTSVCCYCS

    Target    HNCLLRAHV--KNGVIVRISPTYGYGKATDLAGNQASHRWDPRICQKGLILGRRIYGDRRVKAPMIRKGFKEWADAGFPR
    1h0h.1.A  VGCGLIVHTDKKTNRAINVEGD------------PDHPINEGSLCAKGASTWQLAENERRPANPLYRA------------

    Target    HDDGTPRADMEKRGYDEWLQIPWDEALAIAAKTLQNVAETYKGEDGAG-KLLEQGYEPAMVEAMHGAGVQAIKMRGGMPL
    1h0h.1.A  ------------PGSDQWEEKSWDWMLDTIAERVAKTREATFVTKNAKGQVVNRC--------------DGIA-------

    Target    LGAGRVFGFYRFANMLALLDGKLRPEAPPEEIVGSRAFDNYAWHTDLP--PGHPMVSGSQTVDFDLFAAEHSKLLVLIGM
    1h0h.1.A  -----SVGSAAMDNEECWIYQAWLR------SLGLFYIEHQARIUHSATVAALAESYGRGAMTNHWIDLKNSDVILMMGS

    Target    NWICTKMPDAHWIGDARLKGTRVVVISADYMPTANKADEIVILRPGTDTAFLLGVARELITKKLYDRDAVIQRTDLPLLV
    1h0h.1.A  NPAENHPISFKWVMRAKDKGATLIHVDPRYTRTSTKCDLYAPLRSGSDIAFLNGMTKYILEKELYFKDYVVNYTNASFIV

    Target    RLDTGERLSARDVFEGYRQAPLENYVALKTEEELAAPPSPPFTADKQVVPTELREEWGDFVYWDRATNGPAAVNRDEIGA
    1h0h.1.A  GEGF---AFEEGLF----------------------------------------------AGYNKETRKYDKSKW-----

    Target    KFAGDPALLGAFDVTLVDGTNVKARTAFSLLKEYLDENFDVQTTSEVCNVDPAAVRSLARQLAANK---GNALLAAGMGP
    1h0h.1.A  --GFERDENGNP---KRDETLKHPRCVFQIMKKHYE-RYDLDKISAICGTPKELILKVYDAYCATGKPDKAGTIMYAMGW

    Target    NHYFNADLFGRVHFLVAALTDNIGHFSGNVGSYAGNY--RGSLFQAMGQWIAENPFDQE---------A----DL----T
    1h0h.1.A  TQHTVGVQNIRAMSINQLLLGNIGVAGGGVNALRGEANVQGST--DHGLLMHIYPGYLGTARASIPTYEEYTKKFTPVSK

    Target    KPARVKRYFKS------ESAHYWNYGDR-------------PLVSPSEIITGKSHMPTPTKLIWFGNSNSLLGNAKWSFD
    1h0h.1.A  DPQSANWWSNFPKYSASYIKSMWPDADLNEAYGYLPKGEDGKDYSWLTLFDDM--FQGKIKGFFAWGQNPACSGAN--SN

    Target    VVKNTLPKQDAVFCNEWHWTSSCEYS-------------DLVFPADSWAEFKLPDMTASCTNPFLLAFPKTPLARIHNTR
    1h0h.1.A  KTREALTKLDWMVNVNIFDNETGSFWRGPDMDPKKIKTEVFFLPCAVAIEKE--GSI-SNSGRWMQWRYV-GPEPRKNAI

    Target    SDYEILAGVAAALADLVDEPRMKTYWKGILDGDPTPYLQRVLSGSNATRGILYEDLHASSAKGVPLLMNARTYPRHAGWE
    1h0h.1.A  PDGDLIVELAKRVQK-----------------------------------------------------------------

    Target    QRQEDKPWYTPTGRLEFYRPEPEWQAAGESLPIWREPVDATFYEPNAILANSKHPSINPRAPEDYGVPESQMDVETRQYR
    1h0h.1.A  --------------------------------------------------------------------------------

    Target    NVVRTWQELKLSKHPLTEKDPAYRFVFQTPKYRWGAHSTAVDSDWIAMLFGPFGDPYRRDSRTPWTGEAYAEINPRDAKE
    1h0h.1.A  --------------------------------------------------------------------------------

    Target    LGLKDGDYIWLDADPEDRPYRGADSSDEFYDVARAMMRVRIYSGMPRRVIRTWFNMYAATPGTVQAQKDVPGGPAQNQDT
    1h0h.1.A  --------------------------------------------------------------------------------

    Target    GYVALFRHGSHQSGTRAYLRPTQMTDSMNRKAYFGQTIGKGFEADVHSPSGAPKEGYVKVEKAEDGGDEGVGEWRPVTLG
    1h0h.1.A  --------------------------------------------------------------------------------

    Target    LRPDDPSEAMQAYLAGEFVTRKRKGS
    1h0h.1.A  --------------------------

### Model #04 | File | Built with | Oligo-State | Ligands | GMQE | QMEANDisCo Global
--- | --- | --- | --- | --- | --- | ---
| PDB | ProMod3 3.2.1 | monomer | None | 0.14 | 0.44 ± 0.05

Template | Seq Identity | Oligo-state | QSQE | Found by | Method | Resolution | Seq Similarity | Range | Coverage | Description
--- | --- | --- | --- | --- | --- | --- | --- | --- | --- | ---
3ir7.1.A | 30.59 | monomer | 0.00 | BLAST | X-ray | 2.50Å | 0.35 | 54 - 432 | 0.29 | Respiratory nitrate reductase 1 alpha chain

### Excluded ligands

Ligand Name.Number | Reason for Exclusion | Description
--- | --- | ---
6MO.4 | Binding site not conserved. | MOLYBDENUM(VI) ION
AGA.5 | Binding site not conserved. | (1S)-2-{[{[(2S)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PENTANOYLOXY)METHYL]ETHYL OCTANOATE
F3S.9 | Binding site not conserved. | FE3-S4 CLUSTER
HEM.10 | Binding site not conserved. | PROTOPORPHYRIN IX CONTAINING FE
HEM.11 | Binding site not conserved. | PROTOPORPHYRIN IX CONTAINING FE
MD1.1 | Binding site not conserved. | PHOSPHORIC ACID 4-(2-AMINO-4-OXO-3,4,5,6,-TETRAHYDRO-PTERIDIN-6-YL)-2-HYDROXY-3,4-DIMERCAPTO-BUT-3-EN-YL ESTER GUANYLATE ESTER
MD1.2 | Binding site not conserved. | PHOSPHORIC ACID 4-(2-AMINO-4-OXO-3,4,5,6,-TETRAHYDRO-PTERIDIN-6-YL)-2-HYDROXY-3,4-DIMERCAPTO-BUT-3-EN-YL ESTER GUANYLATE ESTER
SF4.3 | Binding site not conserved. | IRON/SULFUR CLUSTER
SF4.6 | Binding site not conserved. | IRON/SULFUR CLUSTER
SF4.7 | Binding site not conserved. | IRON/SULFUR CLUSTER
SF4.8 | Binding site not conserved. | IRON/SULFUR CLUSTER

    Target    SDLSRRELLKRAVVVGTGAGLAELFLPAQFLSSASAQSEPQAVAIANPLAQMPDRSWERIYRDQFAEEDSFVFTCAPNDT
    3ir7.1.A  -----------------------------------------------------NRDWEDGYRQRWQHDKIVRSTHGVNCT

    Target    HNCLLRAHVKNGVIVRISPTYGYGKAT-DLAGNQASHRWDPRICQKGLILGRRIYGDRRVKAPMIRKGF-KEWADAGFPR
    3ir7.1.A  GSCSWKIYVKNGLVTWETQQTDYPRTRPDLPNHE------PRGCPSGASYSWYLYSANRLKYPMMRKRLMKMWREAKALH

    Target    HDDGTPRADMEKRGYDEWLQIPWDEALAIAAKTLQNVAETYKGEDGAGKLLEQGYEPAMVEAMHGAGVQAIKMRGGMPLL
    3ir7.1.A  SDP-----------VEAWASIIED----------ADKAKSFKQARGRGGFVRSSWQ-EVNELIAASNVYTIKN------Y

    Target    GAGRVFGFYRF--ANMLALLDGKLRPEAPPEEIVGSRAFDNYAWHTDLPPGHPMVSGSQTVDFDLFAAEHSKLLVLIGMN
    3ir7.1.A  GPDRVAGFSPIPAMSMVSYASG-----ARYLSLIGGTCLSFYDWYCDLPPASPQTWGEQTDVPESADWYNSSYIIAWGSN

    Target    WICTKMPDAHWIGDARLKGTRVVVISADYMPTANKADEIVILRPGTDTAFLLGVARELITK------KLYDRDAVIQRTD
    3ir7.1.A  VPQTRTPDAHFFTEVRYKGTKTVAVTPDYAEIAKLCDLWLAPKQGTDAAMALAMGHVMLREFHLDNPSQYFTDYVRRYTD

    Target    LPLLVRLD-------TGERLSARDVFE--GYRQAPLENYVALKTEEELAAPPSPPFTADKQVVPTELREEWGDFVYWDRA
    3ir7.1.A  MPMLVMLEERDGYYAAGRMLRAADLVDALGQENNPEWKTVAFNTNGEMVAP-----------------------------

    Target    TNGPAAVNRDEIGAKFAGDPALLGAFDVTLVDGTNVKARTAFSLLKEYLDENFDVQTTSEVCNVDPAAVRSLARQLAANK
    3ir7.1.A  --------------------------------------------------------------------------------

    Target    GNALLAAGMGPNHYFNADLFGRVHFLVAALTDNIGHFSGNVGSYAGNYRGSLFQAMGQWIAENPFDQEADLTKPARVKRY
    3ir7.1.A  --------------------------------------------------------------------------------

    Target    FKSESAHYWNYGDRPLVSPSEIITGKSHMPTPTKLIWFGNSNSLLGNAKWSFDVVKNTLPKQDAVFCNEWHWTSSCEYSD
    3ir7.1.A  --------------------------------------------------------------------------------

    Target    LVFPADSWAEFKLPDMTASCTNPFLLAFPKTPLARIHNTRSDYEILAGVAAALADLVDEPRMKTYWKGILDGDPTPYLQR
    3ir7.1.A  --------------------------------------------------------------------------------

    Target    VLSGSNATRGILYEDLHASSAKGVPLLMNARTYPRHAGWEQRQEDKPWYTPTGRLEFYRPEPEWQAAGESLPIWREPVDA
    3ir7.1.A  --------------------------------------------------------------------------------

    Target    TFYEPNAILANSKHPSINPRAPEDYGVPESQMDVETRQYRNVVRTWQELKLSKHPLTEKDPAYRFVFQTPKYRWGAHSTA
    3ir7.1.A  --------------------------------------------------------------------------------

    Target    VDSDWIAMLFGPFGDPYRRDSRTPWTGEAYAEINPRDAKELGLKDGDYIWLDADPEDRPYRGADSSDEFYDVARAMMRVR
    3ir7.1.A  --------------------------------------------------------------------------------

    Target    IYSGMPRRVIRTWFNMYAATPGTVQAQKDVPGGPAQNQDTGYVALFRHGSHQSGTRAYLRPTQMTDSMNRKAYFGQTIGK
    3ir7.1.A  --------------------------------------------------------------------------------

    Target    GFEADVHSPSGAPKEGYVKVEKAEDGGDEGVGEWRPVTLGLRPDDPSEAMQAYLAGEFVTRKRKGS
    3ir7.1.A  ------------------------------------------------------------------

### Model #05 | File | Built with | Oligo-State | Ligands | GMQE | QMEANDisCo Global
--- | --- | --- | --- | --- | --- | ---
| PDB | ProMod3 3.2.1 | monomer | None | 0.11 | 0.38 ± 0.05

Template | Seq Identity | Oligo-state | QSQE | Found by | Method | Resolution | Seq Similarity | Range | Coverage | Description
--- | --- | --- | --- | --- | --- | --- | --- | --- | --- | ---
6sdv.1.A | 26.79 | monomer | 0.00 | BLAST | X-ray | 1.90Å | 0.33 | 76 - 415 | 0.24 | Formate dehydrogenase, alpha subunit, selenocysteine-containing,Formate dehydrogenase, alpha subunit, selenocysteine-containing,W-formate dehydrogenase - alpha subunit

### Excluded ligands

Ligand Name.Number | Reason for Exclusion | Description
--- | --- | ---
GOL.6 | Not biologically relevant. | GLYCEROL
GOL.7 | Not biologically relevant. | GLYCEROL
GOL.8 | Not biologically relevant. | GLYCEROL
GOL.9 | Not biologically relevant. | GLYCEROL
GOL.10 | Not biologically relevant. | GLYCEROL
GOL.11 | Not biologically relevant. | GLYCEROL
GOL.12 | Not biologically relevant. | GLYCEROL
GOL.13 | Not biologically relevant. | GLYCEROL
GOL.14 | Not biologically relevant. | GLYCEROL
GOL.15 | Not biologically relevant. | GLYCEROL
H2S.5 | Binding site not conserved. | HYDROSULFURIC ACID
MGD.1 | Binding site not conserved. | 2-AMINO-5,6-DIMERCAPTO-7-METHYL-3,7,8A,9-TETRAHYDRO-8-OXA-1,3,9,10-TETRAAZA-ANTHRACEN-4-ONE GUANOSINE DINUCLEOTIDE
MGD.2 | Binding site not conserved. | 2-AMINO-5,6-DIMERCAPTO-7-METHYL-3,7,8A,9-TETRAHYDRO-8-OXA-1,3,9,10-TETRAAZA-ANTHRACEN-4-ONE GUANOSINE DINUCLEOTIDE
NO3.16 | Not biologically relevant. | NITRATE ION
NO3.17 | Not biologically relevant. | NITRATE ION
PEG.18 | Not biologically relevant. | DI(HYDROXYETHYL)ETHER
SF4.3 | Binding site not conserved. | IRON/SULFUR CLUSTER
SF4.19 | Binding site not conserved. | IRON/SULFUR CLUSTER
SF4.20 | Binding site not conserved. | IRON/SULFUR CLUSTER
SF4.21 | Binding site not conserved. | IRON/SULFUR CLUSTER
W.4 | Not in contact with model. | TUNGSTEN ION

    Target    SDLSRRELLKRAVVVGTGAGLAELFLPAQFLSSASAQSEPQAVAIANPLAQMPDRSWERIYRDQFAEEDSFVFTCAPNDT
    6sdv.1.A  ---------------------------------------------------------------------------AKQTT

    Target    HNCLLRAHVKNGVIVRISPTYGYGKATDLAGNQASHRWDPRICQKGLILGRRIYGDRRVKAPMIRKGFKEWADAGFPRHD
    6sdv.1.A  SICCYCA-VGCGLIVHTAKD-GQGRAVNVEGDPDHPINEGSLCPKGASIFQLGENDQRGTQPLYRAPFS-----------

    Target    DGTPRADMEKRGYDEWLQIPWDEALAIAAKTLQNVAE-TYKGEDGAGKLLEQGYEPAMVEAMHGAGVQAIKMRGGMPLLG
    6sdv.1.A  -------------DTWKPVTWDFALTEIAKRIKKTRDASFTEKNAAGDLVNR------TEAIASFGSAAMDNEECWAYGN

    Target    AGRVFGFYRFANMLALLDGKLRPEAPPEEIVGSRAFDNYAWHTDLPPGHPMVSGSQTVDFDLFAAEHSKLLVLIGMNWIC
    6sdv.1.A  ILRSLG-------LVYIEHQARIUHSPTVPALAESFGR---------------GAMTNHWNDLA--NSDCILIMGSNAAE

    Target    TKMPDAHWIGDARLKGTRVVVISADYMPTANKADEIVILRPGTDTAFLLGVARELITKKLYDRDAVIQRTDLPLLVRLDT
    6sdv.1.A  NHPIAFKWVLRAKDKGATLIHVDPRFTRTSARCDVYAPIRSGADIPFLGGLIKYILDNKLYFTDYVREYTNASLIV----

    Target    GERLSARD-VFEGYRQAPLENYVALKTEEELAAPPSPPFTADKQVVPTELREEWGDFVYWDRATNGPAAVNRDEIGAKFA
    6sdv.1.A  GEKFSFKDGLFSGYDAA---------------------------------------------------------------

    Target    GDPALLGAFDVTLVDGTNVKARTAFSLLKEYLDENFDVQTTSEVCNVDPAAVRSLARQLAANKGNALLAAGMGPNHYFNA
    6sdv.1.A  --------------------------------------------------------------------------------

    Target    DLFGRVHFLVAALTDNIGHFSGNVGSYAGNYRGSLFQAMGQWIAENPFDQEADLTKPARVKRYFKSESAHYWNYGDRPLV
    6sdv.1.A  --------------------------------------------------------------------------------

    Target    SPSEIITGKSHMPTPTKLIWFGNSNSLLGNAKWSFDVVKNTLPKQDAVFCNEWHWTSSCEYSDLVFPADSWAEFKLPDMT
    6sdv.1.A  --------------------------------------------------------------------------------

    Target    ASCTNPFLLAFPKTPLARIHNTRSDYEILAGVAAALADLVDEPRMKTYWKGILDGDPTPYLQRVLSGSNATRGILYEDLH
    6sdv.1.A  --------------------------------------------------------------------------------

    Target    ASSAKGVPLLMNARTYPRHAGWEQRQEDKPWYTPTGRLEFYRPEPEWQAAGESLPIWREPVDATFYEPNAILANSKHPSI
    6sdv.1.A  --------------------------------------------------------------------------------

    Target    NPRAPEDYGVPESQMDVETRQYRNVVRTWQELKLSKHPLTEKDPAYRFVFQTPKYRWGAHSTAVDSDWIAMLFGPFGDPY
    6sdv.1.A  --------------------------------------------------------------------------------

    Target    RRDSRTPWTGEAYAEINPRDAKELGLKDGDYIWLDADPEDRPYRGADSSDEFYDVARAMMRVRIYSGMPRRVIRTWFNMY
    6sdv.1.A  --------------------------------------------------------------------------------

    Target    AATPGTVQAQKDVPGGPAQNQDTGYVALFRHGSHQSGTRAYLRPTQMTDSMNRKAYFGQTIGKGFEADVHSPSGAPKEGY
    6sdv.1.A  --------------------------------------------------------------------------------

    Target    VKVEKAEDGGDEGVGEWRPVTLGLRPDDPSEAMQAYLAGEFVTRKRKGS
    6sdv.1.A  -------------------------------------------------

### Model #06 | File | Built with | Oligo-State | Ligands | GMQE | QMEANDisCo Global
--- | --- | --- | --- | --- | --- | ---
| PDB | ProMod3 3.2.1 | monomer | None | 0.08 | 0.40 ± 0.05

Template | Seq Identity | Oligo-state | QSQE | Found by | Method | Resolution | Seq Similarity | Range | Coverage | Description
--- | --- | --- | --- | --- | --- | --- | --- | --- | --- | ---
7l5i.1.A | 24.11 | monomer | 0.00 | BLAST | X-ray | 1.73Å | 0.34 | 128 - 389 | 0.19 | Trimethylamine-N-oxide reductase

### Excluded ligands

Ligand Name.Number | Reason for Exclusion | Description
--- | --- | ---
CL.6 | Not biologically relevant. | CHLORIDE ION
EPE.1 | Not biologically relevant. | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID
EPE.2 | Not biologically relevant. | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID
EPE.7 | Not biologically relevant. | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID
MGD.3 | Binding site not conserved. | 2-AMINO-5,6-DIMERCAPTO-7-METHYL-3,7,8A,9-TETRAHYDRO-8-OXA-1,3,9,10-TETRAAZA-ANTHRACEN-4-ONE GUANOSINE DINUCLEOTIDE
MGD.4 | Binding site not conserved. | 2-AMINO-5,6-DIMERCAPTO-7-METHYL-3,7,8A,9-TETRAHYDRO-8-OXA-1,3,9,10-TETRAAZA-ANTHRACEN-4-ONE GUANOSINE DINUCLEOTIDE
MO.5 | Binding site not conserved. | MOLYBDENUM ATOM
O.8 | Binding site not conserved. | OXYGEN ATOM

    Target    SDLSRRELLKRAVVVGTGAGLAELFLPAQFLSSASAQSEPQAVAIANPLAQMPDRSWERIYRDQFAEEDSFVFTCAPNDT
    7l5i.1.A  --------------------------------------------------------------------------------

    Target    HNCLLRAHVKNGVIVRISPTYGYGKATDLAGNQASHRWDPRICQKGLILGRRIYGDRRVKAPMIRKGFKEWADAGFPRHD
    7l5i.1.A  -----------------------------------------------VVADQLYSEARVKCPMVRKGF--LANPG-----

    Target    DGTPRADMEKRGYDEWLQIPWDEALAIAAKTLQNVAETYKGEDGAGKLLEQGYEPAMVEAMHGAGVQAIKMRGGMPLLGA
    7l5i.1.A  ----KSDTTMRGRDEWVRVSWDEALDLVHNQLKRV----RDEHGSTGIFAGSYGWFSCGSLH-----------------A

    Target    GRVFGFYRFANMLALLDG-KLRPEAPPEEIVGSRAFDNYAWHTDLPPGHPMVSGSQTVDFDLFAAEHSKLLVLIGMNWIC
    7l5i.1.A  SRTL-LQRYMNATGGFVGHKGDYSTGAAQVIMPHVLGTIEVYEQQTSWESILESS-----DIIVLWSANPLTTMRIAWMS

    Target    TKMPDAHWIGDARLKGTRVVVISADYMPTANKAD-EIVILRPGTDTAFLLGVARELITKKLYDRDAVIQRTDLPLLVRLD
    7l5i.1.A  TDQKGIEYFKKFQASGKRIICIDPQKSETCQMLNAEWIPVNTATDVPLMLGIAHTLVEQGKHDKDFLKKYT---------

    Target    TGERLSARDVFEGYRQAPLENYVALKTEEELAAPPSPPFTADKQVVPTELREEWGDFVYWDRATNGPAAVNRDEIGAKFA
    7l5i.1.A  --------------------------------------------------------------------------------

    Target    GDPALLGAFDVTLVDGTNVKARTAFSLLKEYLDENFDVQTTSEVCNVDPAAVRSLARQLAANKGNALLAAGMGPNHYFNA
    7l5i.1.A  --------------------------------------------------------------------------------

    Target    DLFGRVHFLVAALTDNIGHFSGNVGSYAGNYRGSLFQAMGQWIAENPFDQEADLTKPARVKRYFKSESAHYWNYGDRPLV
    7l5i.1.A  --------------------------------------------------------------------------------

    Target    SPSEIITGKSHMPTPTKLIWFGNSNSLLGNAKWSFDVVKNTLPKQDAVFCNEWHWTSSCEYSDLVFPADSWAEFKLPDMT
    7l5i.1.A  --------------------------------------------------------------------------------

    Target    ASCTNPFLLAFPKTPLARIHNTRSDYEILAGVAAALADLVDEPRMKTYWKGILDGDPTPYLQRVLSGSNATRGILYEDLH
    7l5i.1.A  --------------------------------------------------------------------------------

    Target    ASSAKGVPLLMNARTYPRHAGWEQRQEDKPWYTPTGRLEFYRPEPEWQAAGESLPIWREPVDATFYEPNAILANSKHPSI
    7l5i.1.A  --------------------------------------------------------------------------------

    Target    NPRAPEDYGVPESQMDVETRQYRNVVRTWQELKLSKHPLTEKDPAYRFVFQTPKYRWGAHSTAVDSDWIAMLFGPFGDPY
    7l5i.1.A  --------------------------------------------------------------------------------

    Target    RRDSRTPWTGEAYAEINPRDAKELGLKDGDYIWLDADPEDRPYRGADSSDEFYDVARAMMRVRIYSGMPRRVIRTWFNMY
    7l5i.1.A  --------------------------------------------------------------------------------

    Target    AATPGTVQAQKDVPGGPAQNQDTGYVALFRHGSHQSGTRAYLRPTQMTDSMNRKAYFGQTIGKGFEADVHSPSGAPKEGY
    7l5i.1.A  --------------------------------------------------------------------------------

    Target    VKVEKAEDGGDEGVGEWRPVTLGLRPDDPSEAMQAYLAGEFVTRKRKGS
    7l5i.1.A  -------------------------------------------------

### Model #07 | File | Built with | Oligo-State | Ligands | GMQE | QMEANDisCo Global
--- | --- | --- | --- | --- | --- | ---
| PDB | ProMod3 3.2.1 | monomer | None | 0.07 | 0.36 ± 0.05

Template | Seq Identity | Oligo-state | QSQE | Found by | Method | Resolution | Seq Similarity | Range | Coverage | Description
--- | --- | --- | --- | --- | --- | --- | --- | --- | --- | ---
1eu1.1.A | 33.04 | monomer | 0.00 | BLAST | X-ray | 1.30Å | 0.36 | 133 - 401 | 0.19 | DIMETHYL SULFOXIDE REDUCTASE

### Excluded ligands

Ligand Name.Number | Reason for Exclusion | Description
--- | --- | ---
6MO.8 | Binding site not conserved. | MOLYBDENUM(VI) ION
CD.5 | Binding site not conserved. | CADMIUM ION
EPE.11 | Not biologically relevant. | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID
GLC.1 | Not in contact with model. | alpha-D-glucopyranose
GLC.2 | Binding site not conserved. | alpha-D-glucopyranose
GLC.3 | Binding site not conserved. | alpha-D-glucopyranose
MGD.6 | Binding site not conserved. | 2-AMINO-5,6-DIMERCAPTO-7-METHYL-3,7,8A,9-TETRAHYDRO-8-OXA-1,3,9,10-TETRAAZA-ANTHRACEN-4-ONE GUANOSINE DINUCLEOTIDE
MGD.7 | Binding site not conserved. | 2-AMINO-5,6-DIMERCAPTO-7-METHYL-3,7,8A,9-TETRAHYDRO-8-OXA-1,3,9,10-TETRAAZA-ANTHRACEN-4-ONE GUANOSINE DINUCLEOTIDE
O.9 | Binding site not conserved. | OXYGEN ATOM
O.10 | Binding site not conserved. | OXYGEN ATOM
SO4.4 | Not biologically relevant. | SULFATE ION

    Target    SDLSRRELLKRAVVVGTGAGLAELFLPAQFLSSASAQSEPQAVAIANPLAQMPDRSWERIYRDQFAEEDSFVFTCAPNDT
    1eu1.1.A  --------------------------------------------------------------------------------

    Target    HNCLLRAHVKNGVIVRISPTYGYGKATDLAGNQASHRWDPRICQKGLILGRRIYGDRRVKAPMIRKGFKEWADAGFPRHD
    1eu1.1.A  ----------------------------------------------------IYSPTRIKYPMVRREFLEKG--------

    Target    DGTPRADMEKRGYDEWLQIPWDEALAIAAKTLQNVAETYKGEDGAGKLLEQGYEPAMVEAMHGAGVQAIKMRGGMPLLGA
    1eu1.1.A  ---VNADRSTRGNGDFVRVTWDEALDLVARELKRVQESY----GPTGTFGGSYGWKSPGRLHNCQVL---MRRALNLAG-

    Target    GRVFGFYRFANMLALLDGKLRPEAPPEEIVGSRAFDNYAWHTDLPPGHPMVSGSQTVDFDLFAAEHSKLLVL-----IGM
    1eu1.1.A  GFVNSSGDYSTAAAQI---IMP-----HVMGT--LEVYEQQTAWP----------------VVVENTDLMVFWAADPMKT

    Target    NWICTKMPD-AHWIGDARLK--GTRVVVISADYMPTANK-ADEIVILRPGTDTAFLLGVARELITKKLYDRDAVIQ-RTD
    1eu1.1.A  NEIGWVIPDHGAYAGMKALKEKGTRVICINPVRTETADYFGADVVSPRPQTDVALMLGMAHTLYSEDLHDKDFLENCTTG

    Target    LPLLVRLDTGERLSARDVFEGYRQAPLENYVALKTEEELAAPPSPPFTADKQVVPTELREEWGDFVYWDRATNGPAAVNR
    1eu1.1.A  FDLFAAYLTGE---------------------------------------------------------------------

    Target    DEIGAKFAGDPALLGAFDVTLVDGTNVKARTAFSLLKEYLDENFDVQTTSEVCNVDPAAVRSLARQLAANKGNALLAAGM
    1eu1.1.A  --------------------------------------------------------------------------------

    Target    GPNHYFNADLFGRVHFLVAALTDNIGHFSGNVGSYAGNYRGSLFQAMGQWIAENPFDQEADLTKPARVKRYFKSESAHYW
    1eu1.1.A  --------------------------------------------------------------------------------

    Target    NYGDRPLVSPSEIITGKSHMPTPTKLIWFGNSNSLLGNAKWSFDVVKNTLPKQDAVFCNEWHWTSSCEYSDLVFPADSWA
    1eu1.1.A  --------------------------------------------------------------------------------

    Target    EFKLPDMTASCTNPFLLAFPKTPLARIHNTRSDYEILAGVAAALADLVDEPRMKTYWKGILDGDPTPYLQRVLSGSNATR
    1eu1.1.A  --------------------------------------------------------------------------------

    Target    GILYEDLHASSAKGVPLLMNARTYPRHAGWEQRQEDKPWYTPTGRLEFYRPEPEWQAAGESLPIWREPVDATFYEPNAIL
    1eu1.1.A  --------------------------------------------------------------------------------

    Target    ANSKHPSINPRAPEDYGVPESQMDVETRQYRNVVRTWQELKLSKHPLTEKDPAYRFVFQTPKYRWGAHSTAVDSDWIAML
    1eu1.1.A  --------------------------------------------------------------------------------

    Target    FGPFGDPYRRDSRTPWTGEAYAEINPRDAKELGLKDGDYIWLDADPEDRPYRGADSSDEFYDVARAMMRVRIYSGMPRRV
    1eu1.1.A  --------------------------------------------------------------------------------

    Target    IRTWFNMYAATPGTVQAQKDVPGGPAQNQDTGYVALFRHGSHQSGTRAYLRPTQMTDSMNRKAYFGQTIGKGFEADVHSP
    1eu1.1.A  --------------------------------------------------------------------------------

    Target    SGAPKEGYVKVEKAEDGGDEGVGEWRPVTLGLRPDDPSEAMQAYLAGEFVTRKRKGS
    1eu1.1.A  ---------------------------------------------------------

## Materials and Methods

## Template Search

Template search with has been performed against the SWISS-MODEL template library (SMTL, last update: 2023-03-23, last included PDB release: 2023-03-17).

## Template Selection

For each identified template, the template's quality has been predicted from features of the target-template alignment. The templates with the highest quality have then been selected for model building.

## Model Building

Models are built based on the target-template alignment using ProMod3 (Studer et al.). Coordinates which are conserved between the target and the template are copied from the template to the model. Insertions and deletions are remodelled using a fragment library. Side chains are then rebuilt. Finally, the geometry of the resulting model is regularized by using a force field.

## Model Quality Estimation

The global and per-residue model quality has been assessed using the QMEAN scoring function (Studer et al.).

## Ligand Modelling

Ligands present in the template structure are transferred by homology to the model when the following criteria are met: (a) The ligands are annotated as biologically relevant in the template library, (b) the ligand is in contact with the model, (c) the ligand is not clashing with the protein, (d) the residues in contact with the ligand are conserved between the target and the template. If any of these four criteria is not satisfied, a certain ligand will not be included in the model. The model summary includes information on why and which ligand has not been included.

## Oligomeric State Conservation

The quaternary structure annotation of the template is used to model the target sequence in its oligomeric form. The method (Bertoni et al.) is based on a supervised machine learning algorithm, Support Vector Machines (SVM), which combines interface conservation, structural clustering, and other template features to provide a quaternary structure quality estimate (QSQE). The QSQE score is a number between 0 and 1, reflecting the expected accuracy of the interchain contacts for a model built based a given alignment and template. Higher numbers indicate higher reliability. This complements the GMQE score which estimates the accuracy of the tertiary structure of the resulting model.

## References

- BLAST
  Camacho, C., Coulouris, G., Avagyan, V., Ma, N., Papadopoulos, J., Bealer, K., Madden, T.L. BLAST+: architecture and applications. BMC Bioinformatics 10, 421-430 (2009).
- HHblits
  Steinegger, M., Meier, M., Mirdita, M., Vöhringer, H., Haunsberger, S. J., Söding, J. HH-suite3 for fast remote homology detection and deep protein annotation. BMC Bioinformatics 20, 473 (2019).

## Table T1:

Primary amino acid sequence for which templates were searched and models were built.

SDLSRRELLKRAVVVGTGAGLAELFLPAQFLSSASAQSEPQAVAIANPLAQMPDRSWERIYRDQFAEEDSFVFTCAPNDTHNCLLRAHVKNGVIVRISPT
YGYGKATDLAGNQASHRWDPRICQKGLILGRRIYGDRRVKAPMIRKGFKEWADAGFPRHDDGTPRADMEKRGYDEWLQIPWDEALAIAAKTLQNVAETYK
GEDGAGKLLEQGYEPAMVEAMHGAGVQAIKMRGGMPLLGAGRVFGFYRFANMLALLDGKLRPEAPPEEIVGSRAFDNYAWHTDLPPGHPMVSGSQTVDFD
LFAAEHSKLLVLIGMNWICTKMPDAHWIGDARLKGTRVVVISADYMPTANKADEIVILRPGTDTAFLLGVARELITKKLYDRDAVIQRTDLPLLVRLDTG
ERLSARDVFEGYRQAPLENYVALKTEEELAAPPSPPFTADKQVVPTELREEWGDFVYWDRATNGPAAVNRDEIGAKFAGDPALLGAFDVTLVDGTNVKAR
TAFSLLKEYLDENFDVQTTSEVCNVDPAAVRSLARQLAANKGNALLAAGMGPNHYFNADLFGRVHFLVAALTDNIGHFSGNVGSYAGNYRGSLFQAMGQW
IAENPFDQEADLTKPARVKRYFKSESAHYWNYGDRPLVSPSEIITGKSHMPTPTKLIWFGNSNSLLGNAKWSFDVVKNTLPKQDAVFCNEWHWTSSCEYS
DLVFPADSWAEFKLPDMTASCTNPFLLAFPKTPLARIHNTRSDYEILAGVAAALADLVDEPRMKTYWKGILDGDPTPYLQRVLSGSNATRGILYEDLHAS
SAKGVPLLMNARTYPRHAGWEQRQEDKPWYTPTGRLEFYRPEPEWQAAGESLPIWREPVDATFYEPNAILANSKHPSINPRAPEDYGVPESQMDVETRQY
RNVVRTWQELKLSKHPLTEKDPAYRFVFQTPKYRWGAHSTAVDSDWIAMLFGPFGDPYRRDSRTPWTGEAYAEINPRDAKELGLKDGDYIWLDADPEDRP
YRGADSSDEFYDVARAMMRVRIYSGMPRRVIRTWFNMYAATPGTVQAQKDVPGGPAQNQDTGYVALFRHGSHQSGTRAYLRPTQMTDSMNRKAYFGQTIG
KGFEADVHSPSGAPKEGYVKVEKAEDGGDEGVGEWRPVTLGLRPDDPSEAMQAYLAGEFVTRKRKGS

## Table T2:

Template | Seq Identity | Oligo-state | QSQE | Found by | Method | Resolution | Seq Similarity | Coverage | Description
--- | --- | --- | --- | --- | --- | --- | --- | --- | ---
7b04.1.B | 40.77 | monomer | - | BLAST | X-ray | 2.97Å | 0.41 | 0.96 | Nitrite oxidoreductase subunit A
7b04.1.B | 39.64 | monomer | - | HHblits | X-ray | 2.97Å | 0.40 | 0.96 | Nitrite oxidoreductase subunit A
7b04.2.B | 40.77 | monomer | - | BLAST | X-ray | 2.97Å | 0.41 | 0.96 | Nitrite oxidoreductase subunit A
7b04.2.B | 39.64 | monomer | - | HHblits | X-ray | 2.97Å | 0.40 | 0.96 | Nitrite oxidoreductase subunit A
4ydd.1.A | 25.48 | monomer | - | HHblits | X-ray | 1.86Å | 0.33 | 0.71 | DMSO reductase family type II enzyme, molybdopterin subunit
5e7o.1.A | 25.82 | monomer | - | HHblits | X-ray | 2.40Å | 0.33 | 0.71 | DMSO reductase family type II enzyme, molybdopterin subunit
3ir5.1.A | 24.12 | monomer | - | HHblits | X-ray | 2.30Å | 0.32 | 0.78 | Respiratory nitrate reductase 1 alpha chain
1r27.4.A | 23.96 | homo-dimer | 0.14 | HHblits | X-ray | 2.00Å | 0.32 | 0.80 | Respiratory nitrate reductase 1 alpha chain
2ivf.1.A | 24.43 | monomer | - | HHblits | X-ray | 1.88Å | 0.32 | 0.75 | ETHYLBENZENE DEHYDROGENASE ALPHA-SUBUNIT
3egw.1.A | 24.12 | homo-dimer | 0.12 | HHblits | X-ray | 1.90Å | 0.32 | 0.78 | Respiratory nitrate reductase 1 alpha chain
3ir7.1.A | 23.85 | monomer | - | HHblits | X-ray | 2.50Å | 0.32 | 0.80 | Respiratory nitrate reductase 1 alpha chain
1q16.1.A | 24.04 | monomer | - | HHblits | X-ray | 1.90Å | 0.32 | 0.78 | Respiratory nitrate reductase 1 alpha chain
3ir6.1.A | 23.85 | monomer | - | HHblits | X-ray | 2.80Å | 0.32 | 0.80 | Respiratory nitrate reductase 1 alpha chain
5e7o.1.A | 28.33 | monomer | - | BLAST | X-ray | 2.40Å | 0.34 | 0.60 | DMSO reductase family type II enzyme, molybdopterin subunit
4ydd.1.A | 28.33 | monomer | - | BLAST | X-ray | 1.86Å | 0.35 | 0.60 | DMSO reductase family type II enzyme, molybdopterin subunit
1e60.1.A | 20.00 | monomer | - | HHblits | X-ray | 2.00Å | 0.30 | 0.63 | Dimethyl sulfoxide/trimethylamine N-oxide reductase
1e18.1.A | 19.86 | monomer | - | HHblits | X-ray | 2.00Å | 0.30 | 0.63 | DMSO REDUCTASE.
1e5v.2.A | 19.84 | monomer | - | HHblits | X-ray | 2.40Å | 0.30 | 0.63 | Dimethyl sulfoxide/trimethylamine N-oxide reductase
4dmr.1.A | 20.06 | monomer | - | HHblits | X-ray | 1.90Å | 0.30 | 0.59 | DMSO REDUCTASE
1dms.1.A | 20.64 | monomer | - | HHblits | X-ray | 1.88Å | 0.30 | 0.59 | DMSO REDUCTASE
1h0h.1.A | 17.09 | monomer | - | HHblits | X-ray | 1.80Å | 0.28 | 0.47 | FORMATE DEHYDROGENASE SUBUNIT ALPHA
2ivf.1.A | 36.10 | monomer | - | BLAST | X-ray | 1.88Å | 0.38 | 0.38 | ETHYLBENZENE DEHYDROGENASE ALPHA-SUBUNIT
6q8o.1.C | 17.17 | monomer | - | HHblits | X-ray | 3.61Å | 0.27 | 0.42 | NADH-quinone oxidoreductase subunit 3
3m9s.1.C | 17.17 | monomer | - | HHblits | X-ray | 4.50Å | 0.27 | 0.42 | NADH-quinone oxidoreductase subunit 3
6ziy.1.C | 17.17 | monomer | - | HHblits | EM | NA | 0.27 | 0.42 | NADH-quinone oxidoreductase subunit 3
6zjl.1.C | 17.17 | monomer | - | HHblits | EM | NA | 0.27 | 0.42 | NADH-quinone oxidoreductase subunit 3
6zjn.1.C | 17.17 | monomer | - | HHblits | EM | NA | 0.27 | 0.42 | NADH-quinone oxidoreductase subunit 3
2fug.2.C | 17.17 | monomer | - | HHblits | X-ray | 3.30Å | 0.27 | 0.42 | NADH-quinone oxidoreductase chain 3
6zjy.1.C | 17.17 | monomer | - | HHblits | EM | NA | 0.27 | 0.42 | NADH-quinone oxidoreductase subunit 3
6zk9.1.C | 14.65 | monomer | - | HHblits | EM | NA | 0.27 | 0.33 | NADH:ubiquinone oxidoreductase core subunit S1
7zd6.1.4 | 14.40 | monomer | - | HHblits | EM | NA | 0.27 | 0.33 | NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial
6qcf.1.C | 14.40 | monomer | - | HHblits | EM | NA | 0.27 | 0.33 | NADH:ubiquinone oxidoreductase core subunit S1
6qc5.1.C | 14.40 | monomer | - | HHblits | EM | NA | 0.27 | 0.33 | NADH:ubiquinone oxidoreductase core subunit S1
7qsd.1.G | 14.65 | monomer | - | HHblits | EM | NA | 0.27 | 0.33 | NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial
5o31.1.8 | 14.91 | monomer | - | HHblits | EM | 4.13Å | 0.27 | 0.33 | NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial
7dgr.10.A | 14.91 | monomer | - | HHblits | EM | NA | 0.27 | 0.33 | NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial
3ir7.1.A | 30.59 | monomer | - | BLAST | X-ray | 2.50Å | 0.35 | 0.29 | Respiratory nitrate reductase 1 alpha chain
3ir5.1.A | 30.88 | monomer | - | BLAST | X-ray | 2.30Å | 0.36 | 0.29 | Respiratory nitrate reductase 1 alpha chain
1r27.4.A | 30.59 | homo-dimer | - | BLAST | X-ray | 2.00Å | 0.36 | 0.29 | Respiratory nitrate reductase 1 alpha chain
1q16.1.A | 30.59 | monomer | - | BLAST | X-ray | 1.90Å | 0.36 | 0.29 | Respiratory nitrate reductase 1 alpha chain
3egw.1.A | 30.59 | homo-dimer | - | BLAST | X-ray | 1.90Å | 0.35 | 0.29 | Respiratory nitrate reductase 1 alpha chain
3ir6.1.A | 30.59 | monomer | - | BLAST | X-ray | 2.80Å | 0.36 | 0.29 | Respiratory nitrate reductase 1 alpha chain
6sdv.1.A | 26.79 | monomer | - | BLAST | X-ray | 1.90Å | 0.33 | 0.24 | Formate dehydrogenase, alpha subunit, selenocysteine-containing,Formate dehydrogenase, alpha subunit, selenocysteine-containing,W-formate dehydrogenase - alpha subunit
6sdr.1.A | 26.79 | monomer | - | BLAST | X-ray | 2.10Å | 0.33 | 0.24 | Formate dehydrogenase, alpha subunit, selenocysteine-containing
8bqg.1.A | 26.79 | monomer | - | BLAST | X-ray | 1.95Å | 0.33 | 0.24 | Formate dehydrogenase, alpha subunit, selenocysteine-containing
7l5i.1.A | 24.11 | monomer | - | BLAST | X-ray | 1.73Å | 0.34 | 0.19 | Trimethylamine-N-oxide reductase
7l5s.1.A | 24.11 | monomer | - | BLAST | X-ray | 2.09Å | 0.34 | 0.19 | Trimethylamine-N-oxide reductase
4dmr.1.A | 29.09 | monomer | - | BLAST | X-ray | 1.90Å | 0.35 | 0.19 | DMSO REDUCTASE
1e18.1.A | 29.09 | monomer | - | BLAST | X-ray | 2.00Å | 0.35 | 0.19 | DMSO REDUCTASE.
1eu1.1.A | 33.04 | monomer | - | BLAST | X-ray | 1.30Å | 0.36 | 0.19 | DIMETHYL SULFOXIDE REDUCTASE

The table above shows the top 50 filtered templates. A further 372 templates were found which were considered to be less suitable for modelling than the filtered list.
1aa6.1.A, 1be3.1.E, 1bgy.1.P, 1cz4.1.A, 1cz5.1.A, 1dms.1.A, 1e18.1.A, 1e5v.2.A, 1e60.1.A, 1eu1.1.A, 1fdo.1.A, 1g8j.1.A, 1g8k.1.A, 1h0h.1.A, 1ici.1.A, 1jeo.1.A, 1kb9.1.E, 1kqf.1.A, 1l0l.1.E, 1l0n.1.E, 1m2g.1.A, 1m2h.1.A, 1m2j.1.A, 1m2k.1.A, 1m2n.1.A, 1m2n.1.B, 1ma3.1.A, 1ntk.1.E, 1ntm.1.E, 1ogy.1.A, 1q16.1.A, 1q90.1.E, 1r27.4.A, 1s5p.1.A, 1s7g.1.A, 1s7g.1.B, 1s7g.1.C, 1s7g.1.D, 1s7g.1.E, 1sqb.1.E, 1sqp.1.P, 1sqq.1.P, 1sqv.1.E, 1tmo.1.A, 1uhd.1.B, 1uhe.1.B, 1vf5.1.D, 1vf5.1.L, 1wlf.1.A, 1x94.1.A, 1x94.1.B, 1yc5.1.A, 1zrt.1.C, 1zrt.1.F, 2a3n.1.A, 2b4y.1.A, 2b4y.3.A, 2d2c.1.D, 2d2c.1.L, 2e75.1.D, 2e76.1.D, 2e7z.1.A, 2fyn.1.C, 2fyn.2.C, 2fyu.1.E, 2h2i.1.A, 2h4h.1.A, 2h59.1.B, 2i2w.1.A, 2i2w.2.B, 2iv2.1.A, 2ivf.1.A, 2ki8.1.A, 2nya.1.A, 2nyr.1.A, 2nyr.1.B, 2pjh.1.B, 2pq4.1.B, 2qjk.1.C, 2qjp.1.C, 2qjy.3.F, 2v3v.1.A, 2v45.1.A, 2vpx.1.D, 2vpz.1.A, 2x3y.1.A, 2ybb.1.b, 3cwb.1.E, 3egw.1.A, 3etn.1.A, 3eua.1.A, 3fj1.1.A, 3h1h.1.E, 3h1h.1.O, 3h1i.1.E, 3ir5.1.A, 3ir6.1.A, 3ir7.1.A, 3jr3.1.A, 3k35.1.A, 3l75.1.E, 3l75.1.O, 3o27.1.A, 3o27.1.B, 3o5a.1.A, 3pki.1.A, 3plx.1.B, 3qc8.1.A, 3qq7.1.A, 3qq8.1.A, 3qwz.1.A, 3riy.2.A, 3sho.1.A, 3sho.1.C, 3tiw.1.A, 3tiw.2.A, 3zg6.1.A, 4aay.1.A, 4aok.1.B, 4aok.1.D, 4bv2.3.A, 4dmr.1.A, 4g1c.1.A, 4g1c.2.A, 4ga5.1.A, 4ga6.1.A, 4h44.1.D, 4hda.1.A, 4hda.2.A, 4ivn.1.A, 4kdi.1.A, 4kdi.2.A, 4kdl.1.A, 4ogq.1.L, 4pv1.1.L, 4rv0.1.A, 4twi.1.A, 4twj.1.A, 4u3f.1.E, 4utn.1.A, 4utn.2.A, 4v4c.1.A, 4wd3.1.A, 4ydd.1.A, 5b6c.1.A, 5bwl.1.A, 5cuo.1.A, 5cup.1.A, 5e7o.1.A, 5e7p.1.A, 5epp.1.A, 5g4f.1.A, 5g4f.1.B, 5g4f.1.C, 5g4f.1.D, 5g4f.1.E, 5g4f.1.F, 5glf.1.A, 5glf.2.A, 5glf.3.A, 5glf.4.A, 5gpn.24.A, 5j8k.55.A, 5kkz.1.C, 5kli.1.C, 5klv.1.P, 5ls7.1.L, 5ltz.1.A, 5lu5.1.A, 5lu6.1.A, 5lu7.1.A, 5mf6.1.A, 5nqd.1.A, 5o31.1.8, 5oj7.1.A, 5ojn.1.A, 5okd.1.E, 5t5i.1.B, 5t5i.1.D, 5x16.1.A, 5x4l.1.A, 5x4l.2.A, 5xhs.1.A, 5xtb.1.L, 5xte.1.C, 5y2f.1.A, 6aco.1.A, 6acp.1.A, 6adq.1.L, 6btm.1.B, 6cz7.1.A, 6enx.1.A, 6eo0.1.A, 6eqs.3.A, 6f0k.1.B, 6fky.1.A, 6fky.2.A, 6flg.1.A, 6g72.1.G, 6gcs.1.A, 6giq.1.E, 6hd3.1.A, 6hu9.1.E, 6hwh.1.A, 6ljk.1.A, 6ljm.1.A, 6lod.1.B, 6nhg.1.E, 6nin.1.C, 6q9e.1.E, 6q9e.1.O, 6qbx.15.A, 6qbx.5.A, 6qc2.33.A, 6qc2.43.A, 6qc3.15.A, 6qc3.5.A, 6qc4.15.A, 6qc4.5.A, 6qc5.1.C, 6qcf.1.C, 6rfq.1.A, 6rfs.1.A, 6rqf.1.D, 6rqf.1.L, 6rxj.1.A, 6rxm.1.A, 6rxm.2.A, 6rxm.3.A, 6rxm.4.A, 6rxm.5.A, 6rxm.6.A, 6rxo.1.A, 6rxo.2.A, 6rxp.2.A, 6rxq.4.A, 6rxs.1.A, 6s6y.1.B, 6sdr.1.A, 6sdv.1.A, 6t0b.1.E, 6t0b.1.O, 6t15.1.E, 6t15.1.O, 6tg9.1.A, 6x89.1.H, 6xvg.3.A, 6yj4.1.G, 6ymx.1.Q, 6ymx.1.Z, 6zk9.1.C, 6zr2.1.G, 7a23.1.O, 7ak5.1.G, 7ak6.1.G, 7aqr.1.F, 7ar7.1.G, 7ar8.1.G, 7arc.1.F, 7b04.1.B, 7b04.2.B, 7bkb.1.F, 7bkb.1.J, 7bkb.1.L, 7cl0.1.A, 7dbo.1.A, 7dbo.2.A, 7dg7.1.A, 7dg9.1.A, 7dgr.10.A, 7dgr.60.A, 7dgs.50.A, 7dgs.60.A, 7di0.1.A, 7di0.2.A, 7di0.3.A, 7di1.1.A, 7du6.1.A, 7du7.1.A, 7dvc.1.A, 7dvc.5.A, 7dvf.1.A, 7dvh.1.A, 7dvh.2.A, 7dvh.4.A, 7dww.1.A, 7dww.2.A, 7dxr.1.A, 7dxr.1.B, 7dxr.2.B, 7dxs.1.A, 7dxs.1.B, 7dxs.2.A, 7dxs.2.B, 7dxt.1.A, 7dxu.1.A, 7dxu.1.B, 7dxu.2.B, 7dxv.1.A, 7dxv.1.B, 7dxw.1.A, 7dxx.1.A, 7dxx.1.B, 7dxy.1.A, 7dxz.1.A, 7dxz.2.A, 7dxz.2.B, 7dxz.3.A, 7dyc.1.A, 7dyc.2.A, 7dyc.3.A, 7e1v.1.P, 7e5z.1.A, 7en5.1.A, 7en6.1.A, 7en6.1.B, 7en6.1.C, 7en6.1.D, 7jrg.1.E, 7l5i.1.A, 7l5s.1.A, 7nz1.1.E, 7o37.1.E, 7o37.1.O, 7o3c.1.E, 7o3c.1.O, 7o3h.1.E, 7o3h.1.O, 7p61.1.C, 7p63.1.C, 7q5y.1.A, 7qrm.1.D, 7qsd.1.G, 7qv7.1.L, 7qv7.1.O, 7r0w.1.L, 7r0w.1.Q, 7rh5.1.V, 7rja.1.H, 7rjb.1.I, 7t2r.1.A, 7t30.1.A, 7tce.2.F, 7tgh.58.A, 7tlj.1.C, 7tz6.1.E, 7tz6.1.P, 7v2c.1.L, 7vw6.1.A, 7vxu.1.L, 7wbb.1.A, 7wbb.1.B, 7wbb.1.C, 7wbb.1.D, 7wbb.1.E, 7wbb.1.G, 7z0t.1.G, 7zd6.1.4, 7zm7.1.I, 7zxy.1.D, 7zxy.1.L, 8asi.1.A, 8asi.1.E, 8asj.1.E, 8b9z.1.G, 8ba0.1.G, 8bel.1.B, 8bel.1.I, 8bpx.51.A, 8bqg.1.A, 8e73.55.A, 8e9g.1.G