|  | SWISS-MODEL Homology Modelling Report

## Model Building Report

This document lists the results for the homology modelling project "4_1_May_SF_Bin52_scaffold_5716_c1_3776-6595_1" submitted to SWISS-MODEL workspace on March 29, 2023, 8:37 p.m..The submitted primary amino acid sequence is given in Table T1.

If you use any results in your research, please cite the relevant publications:

- Waterhouse, A., Bertoni, M., Bienert, S., Studer, G., Tauriello, G., Gumienny, R., Heer, F.T., de Beer, T.A.P., Rempfer, C., Bordoli, L., Lepore, R., Schwede, T. SWISS-MODEL: homology modelling of protein structures and complexes. Nucleic Acids Res. 46(W1), W296-W303 (2018).
- Bienert, S., Waterhouse, A., de Beer, T.A.P., Tauriello, G., Studer, G., Bordoli, L., Schwede, T. The SWISS-MODEL Repository - new features and functionality. Nucleic Acids Res. 45, D313-D319 (2017).
- Studer, G., Tauriello, G., Bienert, S., Biasini, M., Johner, N., Schwede, T. ProMod3 - A versatile homology modelling toolbox. PLOS Comp. Biol. 17(1), e1008667 (2021).
- Studer, G., Rempfer, C., Waterhouse, A.M., Gumienny, G., Haas, J., Schwede, T. QMEANDisCo - distance constraints applied on model quality estimation. Bioinformatics 36, 1765-1771 (2020).
- Bertoni, M., Kiefer, F., Biasini, M., Bordoli, L., Schwede, T. Modeling protein quaternary structure of homo- and hetero-oligomers beyond binary interactions by homology. Scientific Reports 7 (2017).

## Results

The SWISS-MODEL template library (SMTL version 2023-03-23, PDB release 2023-03-17) was searched with for evolutionary related structures matching the target sequence in Table T1. For details on the template search, see Materials and Methods. Overall 411 templates were found (Table T2).

## Models

The following models were built (see Materials and Methods "Model Building"):

### Model #02 | File | Built with | Oligo-State | Ligands | GMQE | QMEANDisCo Global
--- | --- | --- | --- | --- | --- | ---
| PDB | ProMod3 3.2.1 | monomer | 1 x MO: MOLYBDENUM ATOM; | 0.68 | 0.69 ± 0.05

Template | Seq Identity | Oligo-state | QSQE | Found by | Method | Resolution | Seq Similarity | Range | Coverage | Description
--- | --- | --- | --- | --- | --- | --- | --- | --- | --- | ---
7b04.1.B | 39.66 | monomer | 0.00 | HHblits | X-ray | 2.97Å | 0.40 | 29 - 938 | 0.95 | Nitrite oxidoreductase subunit A

### Included Ligands

Ligand | Description
--- | ---
1 x MO | MOLYBDENUM ATOM

### Excluded ligands

Ligand Name.Number | Reason for Exclusion | Description
--- | --- | ---
CA.10 | Binding site not conserved. | CALCIUM ION
CA.11 | Binding site not conserved. | CALCIUM ION
F3S.4 | Binding site not conserved. | FE3-S4 CLUSTER
HEM.9 | Binding site not conserved. | PROTOPORPHYRIN IX CONTAINING FE
MD1.5 | Binding site not conserved. | PHOSPHORIC ACID 4-(2-AMINO-4-OXO-3,4,5,6,-TETRAHYDRO-PTERIDIN-6-YL)-2-HYDROXY-3,4-DIMERCAPTO-BUT-3-EN-YL ESTER GUANYLATE ESTER
MD1.6 | Binding site not conserved. | PHOSPHORIC ACID 4-(2-AMINO-4-OXO-3,4,5,6,-TETRAHYDRO-PTERIDIN-6-YL)-2-HYDROXY-3,4-DIMERCAPTO-BUT-3-EN-YL ESTER GUANYLATE ESTER
SF4.1 | Binding site not conserved. | IRON/SULFUR CLUSTER
SF4.2 | Binding site not conserved. | IRON/SULFUR CLUSTER
SF4.3 | Binding site not conserved. | IRON/SULFUR CLUSTER
SF4.8 | Binding site not conserved. | IRON/SULFUR CLUSTER

    Target    AQGVSRRQLLGRALALGSGAALADLLGPARFLSPAGAATAGAVVPGNPLRVMPDRTWEQIYRNQFEDDSTFVFTCAPNDT
    7b04.1.B  -MKLTRRAFLQVAGATGATLTLAKNAMAFRLLKP-------AVVVDNPLDTYPDRRWESVYRDQYQYDRTFTYCCSPNDT

    Target    HNCLLRAHVKNGVVVRISPTYGYGEATDLYGNRASHRWDPRTCQKGLILSRRFYSERRVKAPMIRKGFKDWVEAGYPRND
    7b04.1.B  HACRIRAFVRNNVMMRVEQNYDHQNYSDLYGNKATRNWNPRMCLKGYTFHRRVYGPYRLRYPLIRKGWKRWADDGFPELT

    Target    DGTP-QMDVTLRGSDDWIRISWDEATTIAAKTMEDVARTF-NGDEGARKLLAQGYHPEMVEVMHGAGVQALKLRGGMPLL
    7b04.1.B  PENKTKYMFDNRGNDELLRASWDEAFTYASKGIIHITKKYSGPEG-AQKLIDQGYPKEMVDRMQGAGTRTFKGRGGMGLL

    Target    GIGRIFGFYRFANMLALLDRKLRPDAPADEILGSRTFDNYAWHTDLPPGHPMVTGSQTVDFDLFSAEHTKLLLIIGMNWI
    7b04.1.B  GVIGKYGMYRFNNCLAIVDAHNRG-VGPDQALGGRNWSNYTWHGDQAPGHPFSHGLQTSDVDMNDVRFSKLLIQTGKNLI

    Target    CTKMPDGHWIGDARLKGTRVIVISADYMPTANKADEVIILRPGTDAAFFLGVARELIEKGLYDRAAVIERTDLPLLVRLD
    7b04.1.B  ENKMPEAHWVTEVMERGGKIVVITPEYSPSAQKADYWIPIRNNTDTALFLGITKILIDNKWYDADYVKKFTDFPLLIRTD

    Target    TGERLDARDVIPGYELAALTNYVTLKPDAEIKGNPPPPPFTAGGQVVPTELRDAWGDFVWWDRATGRPRPVSRDEVG---
    7b04.1.B  TLKRVSPKDIIPNYKLQDISD-----------G---PSYHIQG---LKDEQREIIGDFVVWDAKSKGPKAITRDDVGETL

    Target    ARFDGDPALLGEFEVELVDGSTVPVRPAFDLLKQYLDESFDLRTASEVCRVPPQAIQSIARQLAANKRETLLAAGMGPNH
    7b04.1.B  VKKGIDPVLEGSFKLKTIDGKEIEVMTLLEMYKIHLR-DYDIDSVVSMTNSPKDLIERLAKDIATIKPVA-IHYGEGVNH

    Target    YFQNDLFGRVQFLVAALTDNIGHLGGNVGSYAGNYRGSVFQA---MG-Q---WIAEDPFAIEPDLTKPA------TVKRY
    7b04.1.B  YFHATLMNRSYYLPVMLTGNVGYFGSGSHTWAGNYKAGNFQASKWSGPGFYGWVAEDVF--KPNL-DPYASAKDLNIKGR

    Target    YKAESAHYWNYGERPLRAVAKDDEGDLTKGEVLTGKSHMPTPTKLIWFGNSNSLLGNAKWSFDVVKNTLPRQDAVFCNEW
    7b04.1.B  ALDEEVAYWNHSERPLIV-NT---P-KYGRKVFTGKTHMPSPTKVLWFTNVNLINNAKH-VYQMLKNVNPNIEQIMSTDI

    Target    HWTSSCEYADLVFPADSWAEFKLPDATAS--CTNPFLLAFPTTPLKRLYDTRSDYEALALTAKALGELIDEPRMEQYWRG
    7b04.1.B  EITGSIEYADFAFPANSWVEFQ--EFEITNSCSNPFIQIWGKTGITPVYESKDDVKILAGMASKLGELLRDKRFEDNWKF

    Target    ILDGDPTPYLQRIFSGSNATRGITYDELHESSK--RGVPLLMNMRTYPRSGGWEQRQEDKPWYTATGRLEFYRPEPEFQA
    7b04.1.B  AIEGRASVYINRLLDGSTTMKGYTCEDILNGKYGEPGVAML-LFRTYPRHPFWEQVHESLPFYTPTGRLQAYNDEPEIIE

    Target    AGESLPVWREPVDATFYEPNAILSNAAHPSIAPRAPEDYGVPESQLDVETRQYRNVVRTWAELQQTLHPLQERDPAFRFV
    7b04.1.B  YGENFIVHREGPEATPYLPNAIVS--TNPYIR---PDDYGIPENAEYWEDRTVRNIKKSWEETKKTKNFLWE--KGYHFY

    Target    F
    7b04.1.B  -

### Model #01 | File | Built with | Oligo-State | Ligands | GMQE | QMEANDisCo Global
--- | --- | --- | --- | --- | --- | ---
| PDB | ProMod3 3.2.1 | monomer | 1 x MO: MOLYBDENUM ATOM; | 0.67 | 0.68 ± 0.05

Template | Seq Identity | Oligo-state | QSQE | Found by | Method | Resolution | Seq Similarity | Range | Coverage | Description
--- | --- | --- | --- | --- | --- | --- | --- | --- | --- | ---
7b04.1.B | 41.29 | monomer | 0.00 | BLAST | X-ray | 2.97Å | 0.41 | 47 - 938 | 0.91 | Nitrite oxidoreductase subunit A

### Included Ligands

Ligand | Description
--- | ---
1 x MO | MOLYBDENUM ATOM

### Excluded ligands

Ligand Name.Number | Reason for Exclusion | Description
--- | --- | ---
CA.10 | Binding site not conserved. | CALCIUM ION
CA.11 | Binding site not conserved. | CALCIUM ION
F3S.4 | Binding site not conserved. | FE3-S4 CLUSTER
HEM.9 | Binding site not conserved. | PROTOPORPHYRIN IX CONTAINING FE
MD1.5 | Binding site not conserved. | PHOSPHORIC ACID 4-(2-AMINO-4-OXO-3,4,5,6,-TETRAHYDRO-PTERIDIN-6-YL)-2-HYDROXY-3,4-DIMERCAPTO-BUT-3-EN-YL ESTER GUANYLATE ESTER
MD1.6 | Binding site not conserved. | PHOSPHORIC ACID 4-(2-AMINO-4-OXO-3,4,5,6,-TETRAHYDRO-PTERIDIN-6-YL)-2-HYDROXY-3,4-DIMERCAPTO-BUT-3-EN-YL ESTER GUANYLATE ESTER
SF4.1 | Binding site not conserved. | IRON/SULFUR CLUSTER
SF4.2 | Binding site not conserved. | IRON/SULFUR CLUSTER
SF4.3 | Binding site not conserved. | IRON/SULFUR CLUSTER
SF4.8 | Binding site not conserved. | IRON/SULFUR CLUSTER

    Target    AQGVSRRQLLGRALALGSGAALADLLGPARFLSPAGAATAGAVVPGNPLRVMPDRTWEQIYRNQFEDDSTFVFTCAPNDT
    7b04.1.B  ----------------------------------------------NPLDTYPDRRWESVYRDQYQYDRTFTYCCSPNDT

    Target    HNCLLRAHVKNGVVVRISPTYGYGEATDLYGNRASHRWDPRTCQKGLILSRRFYSERRVKAPMIRKGFKDWVEAGYPRND
    7b04.1.B  HACRIRAFVRNNVMMRVEQNYDHQNYSDLYGNKATRNWNPRMCLKGYTFHRRVYGPYRLRYPLIRKGWKRWADDGFP---

    Target    DGTPQMDVTL----RGSDDWIRISWDEATTIAAKTMEDVARTFNGDEGARKLLAQGYHPEMVEVMHGAGVQALKLRGGMP
    7b04.1.B  ELTPENKTKYMFDNRGNDELLRASWDEAFTYASKGIIHITKKYSGPEGAQKLIDQGYPKEMVDRMQGAGTRTFKGRGGMG

    Target    LLGIGRIFGFYRFANMLALLDRKLRPDAPADEILGSRTFDNYAWHTDLPPGHPMVTGSQTVDFDLFSAEHTKLLLIIGMN
    7b04.1.B  LLGVIGKYGMYRFNNCLAIVDAHNRGVGP-DQALGGRNWSNYTWHGDQAPGHPFSHGLQTSDVDMNDVRFSKLLIQTGKN

    Target    WICTKMPDGHWIGDARLKGTRVIVISADYMPTANKADEVIILRPGTDAAFFLGVARELIEKGLYDRAAVIERTDLPLLVR
    7b04.1.B  LIENKMPEAHWVTEVMERGGKIVVITPEYSPSAQKADYWIPIRNNTDTALFLGITKILIDNKWYDADYVKKFTDFPLLIR

    Target    LDTGERLDARDVIPGYELAALTNYVTLKPDAEIKGNPPPPPFTAGGQVVPTELRDAWGDFVWWDRATGRPRPVSRDEVG-
    7b04.1.B  TDTLKRVSPKDIIPNYKLQDISD----GPSYHIQG-------------LKDEQREIIGDFVVWDAKSKGPKAITRDDVGE

    Target    --ARFDGDPALLGEFEVELVDGSTVPVRPAFDLLKQYLDESFDLRTASEVCRVPPQAIQSIARQLAANKRETLLAAGMGP
    7b04.1.B  TLVKKGIDPVLEGSFKLKTIDGKEIEVMTLLEMYKIHLRD-YDIDSVVSMTNSPKDLIERLAKDIATIK-PVAIHYGEGV

    Target    NHYFQNDLFGRVQFLVAALTDNIGHLGGNVGSYAGNYRGSVFQA-------MGQWIAEDPFAIEPDL-----TKPATVKR
    7b04.1.B  NHYFHATLMNRSYYLPVMLTGNVGYFGSGSHTWAGNYKAGNFQASKWSGPGFYGWVAEDVF--KPNLDPYASAKDLNIKG

    Target    YYKAESAHYWNYGERPLRAVAKDDEGDLTKGEVLTGKSHMPTPTKLIWFGNSNSLLGNAKWSFDVVKNTLPRQDAVFCNE
    7b04.1.B  RALDEEVAYWNHSERPL-IVNTPKYGR----KVFTGKTHMPSPTKVLWFTNVN-LINNAKHVYQMLKNVNPNIEQIMSTD

    Target    WHWTSSCEYADLVFPADSWAEFKLPDATASCTNPFLLAFPTTPLKRLYDTRSDYEALALTAKALGELIDEPRMEQYWRGI
    7b04.1.B  IEITGSIEYADFAFPANSWVEFQEFEITNSCSNPFIQIWGKTGITPVYESKDDVKILAGMASKLGELLRDKRFEDNWKFA

    Target    LDGDPTPYLQRIFSGSNATRGITYDEL--HESSKRGVPLLMNMRTYPRSGGWEQRQEDKPWYTATGRLEFYRPEPEFQAA
    7b04.1.B  IEGRASVYINRLLDGSTTMKGYTCEDILNGKYGEPGVAMLL-FRTYPRHPFWEQVHESLPFYTPTGRLQAYNDEPEIIEY

    Target    GESLPVWREPVDATFYEPNAILSNAAHPSIAPRAPEDYGVPESQLDVETRQYRNVVRTWAELQQTLHPLQERDPAFRFVF
    7b04.1.B  GENFIVHREGPEATPYLPNAIVS--TNPYI---RPDDYGIPENAEYWEDRTVRNIKKSWEETKKTKNFLWEKGYHFYCV-

### Model #03 | File | Built with | Oligo-State | Ligands | GMQE | QMEANDisCo Global
--- | --- | --- | --- | --- | --- | ---
| PDB | ProMod3 3.2.1 | monomer | 1 x 6MO: MOLYBDENUM(VI) ION; | 0.40 | 0.54 ± 0.05

Template | Seq Identity | Oligo-state | QSQE | Found by | Method | Resolution | Seq Similarity | Range | Coverage | Description
--- | --- | --- | --- | --- | --- | --- | --- | --- | --- | ---
3ir5.1.A | 25.36 | monomer | 0.00 | HHblits | X-ray | 2.30Å | 0.33 | 54 - 767 | 0.67 | Respiratory nitrate reductase 1 alpha chain

### Included Ligands

Ligand | Description
--- | ---
1 x 6MO | MOLYBDENUM(VI) ION

### Excluded ligands

Ligand Name.Number | Reason for Exclusion | Description
--- | --- | ---
AGA.5 | Binding site not conserved. | (1S)-2-{[{[(2S)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PENTANOYLOXY)METHYL]ETHYL OCTANOATE
F3S.9 | Binding site not conserved. | FE3-S4 CLUSTER
HEM.10 | Binding site not conserved. | PROTOPORPHYRIN IX CONTAINING FE
HEM.11 | Binding site not conserved. | PROTOPORPHYRIN IX CONTAINING FE
MD1.1 | Binding site not conserved. | PHOSPHORIC ACID 4-(2-AMINO-4-OXO-3,4,5,6,-TETRAHYDRO-PTERIDIN-6-YL)-2-HYDROXY-3,4-DIMERCAPTO-BUT-3-EN-YL ESTER GUANYLATE ESTER
MD1.2 | Binding site not conserved. | PHOSPHORIC ACID 4-(2-AMINO-4-OXO-3,4,5,6,-TETRAHYDRO-PTERIDIN-6-YL)-2-HYDROXY-3,4-DIMERCAPTO-BUT-3-EN-YL ESTER GUANYLATE ESTER
SF4.4 | Binding site not conserved. | IRON/SULFUR CLUSTER
SF4.6 | Binding site not conserved. | IRON/SULFUR CLUSTER
SF4.7 | Binding site not conserved. | IRON/SULFUR CLUSTER
SF4.8 | Binding site not conserved. | IRON/SULFUR CLUSTER

    Target    AQGVSRRQLLGRALALGSGAALADLLGPARFLSPAGAATAGAVVPGNPLRVMPDRTWEQIYRNQFEDDSTFVFTCAPNDT
    3ir5.1.A  -----------------------------------------------------NRDWEDGYRQRWQHDKIVRSTCGVNCT

    Target    HNCLLRAHVKNGVVVRISPTYGYGEATDLYGNRASHRWDPRTCQKGLILSRRFYSERRVKAPMIRKGF-KDWVEAGY---
    3ir5.1.A  GSCSWKIYVKNGLVTWETQQTDYPR-----TRPDLPNHEPRGCPRGASYSWYLYSANRLKYPMMRKRLMKMWREAKALHS

    Target    -PR-------NDDGTPQMDVTLRGSDDWIRISWDEATTIAAKTMEDVARTFNGDEGARKLLAQGYHPEMVEVMHGAGVQA
    3ir5.1.A  DPVEAWASIIEDADKAKSFKQARGRGGFVRSSWQEVNELIAASNVYTIKNYG--------------PDRVAGFSPIPAMS

    Target    LKLRGGMPLLGIGRIFGFYRFANMLALLDRKLRPDAPADEILGSRTFDNYAWHTDLPPGHPMVTGSQTVDFDLFSAEHTK
    3ir5.1.A  MV-----------SYASGARYLS-----------------LIGGTCLSFYDWYCDLPPASPQTWGEQTDVPESADWYNSS

    Target    LLLIIGMNWICTKMPDGHWIGDARLKGTRVIVISADYMPTANKADEVIILRPGTDAAFFLGVARELIEKGL------YDR
    3ir5.1.A  YIIAWGSNVPQTRTPDAHFFTEVRYKGTKTVAVTPDYAEIAKLCDLWLAPKQGTDAAMALAMGHVMLREFHLDNPSQYFT

    Target    AAVIERTDLPLLVRLD-------TGERLDARDVIPGYELAALTNYVTLKPDAEIKGNPPPPPFTAGGQVVPTELRDAWGD
    3ir5.1.A  DYVRRYTDMPMLVMLEERDGYYAAGRMLRAADLVDALGQEN----------------------------------NPEWK

    Target    FVWWDRATGRPRPVSRDE--------------------------------------VG-ARFD-----------GDPALL
    3ir5.1.A  TVAFNT-NGEMVAPNGSIGFRWGEKGKWNLEQRDGKTGEETELQLSLLGSQDEIAEVGFPYFGGDGTEHFNKVELENVLL

    Target    G---EFEVELVDGSTVPVRPAFDLLK------------------QYLDESFDLRTASEVCRVPPQAIQSIARQLAAN---
    3ir5.1.A  HKLPVKRLQLADGSTALVTTVYDLTLANYGLERGLNDVNCATSYDDV-KAYTPAWAEQITGVSRSQIIRIAREFADNADK

    Target    --KRETLLAAGMGPNHYFQNDLFGRVQFLVAALTDNIGHLGGNVGSYAGNYRGSVFQAMGQWIAEDPFAIEP--------
    3ir5.1.A  THGR-SMIIVGAGLNHWYHLDMNYRGLINMLIFCGCVGQSGGGWAHYVGQEKLRPQTGWQPLAFALDWQRPARHMNSTSY

    Target    ----------------DLTKPA-TVKRYYK--------AESAHYW----NYGERPLRAVAKDD-----EGDLTKGEVLTG
    3ir5.1.A  FYNHSSQWRYETVTAEELLSPMADKSRYTGHLIDFNVRAERMGWLPSAPQLGTNPLTIAGEAEKAGMNPVDYTVKSLKEG

    Target    KS--------HMPTPTKLIWFGNSNSLLGNAKWSFDVV------------------------------KNTLPRQDAVFC
    3ir5.1.A  SIRFAAEQPENGKNHPRNLFIWRSNLLGSSGKGHEFMLKYLLGTEHGIQGKDLGQQGGVKPEEVDWQDNGLEGKLDLVVT

    Target    NEWHWTSSCEYADLVFPADSWAEFKLPDATASCTNPFLLAFPTTPLKRLYDTRSDYEALALTAKALGELIDEPRMEQYWR
    3ir5.1.A  LDFRLSSTCLYSDIILPTATWYEK--DDMNTSDMHPFIHPL-SAAVDPAWEAKSDWEIYKAIAKKFSE------------

    Target    GILDGDPTPYLQRIFSGSNATRGITYDELHESSKRGVPLLMNMRTYPRSGGWEQRQEDKPWYTATGRLEFYRPEPEFQAA
    3ir5.1.A  --------------------------------------------------------------------------------

    Target    GESLPVWREPVDATFYEPNAILSNAAHPSIAPRAPEDYGVPESQLDVETRQYRNVVRTWAELQQTLHPLQERDPAFRFVF
    3ir5.1.A  --------------------------------------------------------------------------------

### Model #04 | File | Built with | Oligo-State | Ligands | GMQE | QMEANDisCo Global
--- | --- | --- | --- | --- | --- | ---
| PDB | ProMod3 3.2.1 | monomer | None | 0.37 | 0.48 ± 0.05

Template | Seq Identity | Oligo-state | QSQE | Found by | Method | Resolution | Seq Similarity | Range | Coverage | Description
--- | --- | --- | --- | --- | --- | --- | --- | --- | --- | ---
6sdv.1.A | 18.11 | monomer | 0.00 | HHblits | X-ray | 1.90Å | 0.29 | 54 - 767 | 0.64 | Formate dehydrogenase, alpha subunit, selenocysteine-containing,Formate dehydrogenase, alpha subunit, selenocysteine-containing,W-formate dehydrogenase - alpha subunit

### Excluded ligands

Ligand Name.Number | Reason for Exclusion | Description
--- | --- | ---
GOL.6 | Not biologically relevant. | GLYCEROL
GOL.7 | Not biologically relevant. | GLYCEROL
GOL.8 | Not biologically relevant. | GLYCEROL
GOL.9 | Not biologically relevant. | GLYCEROL
GOL.10 | Not biologically relevant. | GLYCEROL
GOL.11 | Not biologically relevant. | GLYCEROL
GOL.12 | Not biologically relevant. | GLYCEROL
GOL.13 | Not biologically relevant. | GLYCEROL
GOL.14 | Not biologically relevant. | GLYCEROL
GOL.15 | Not biologically relevant. | GLYCEROL
H2S.5 | Binding site not conserved. | HYDROSULFURIC ACID
MGD.1 | Binding site not conserved. | 2-AMINO-5,6-DIMERCAPTO-7-METHYL-3,7,8A,9-TETRAHYDRO-8-OXA-1,3,9,10-TETRAAZA-ANTHRACEN-4-ONE GUANOSINE DINUCLEOTIDE
MGD.2 | Binding site not conserved. | 2-AMINO-5,6-DIMERCAPTO-7-METHYL-3,7,8A,9-TETRAHYDRO-8-OXA-1,3,9,10-TETRAAZA-ANTHRACEN-4-ONE GUANOSINE DINUCLEOTIDE
NO3.16 | Not biologically relevant. | NITRATE ION
NO3.17 | Not biologically relevant. | NITRATE ION
PEG.18 | Not biologically relevant. | DI(HYDROXYETHYL)ETHER
SF4.3 | Binding site not conserved. | IRON/SULFUR CLUSTER
SF4.19 | Binding site not conserved. | IRON/SULFUR CLUSTER
SF4.20 | Binding site not conserved. | IRON/SULFUR CLUSTER
SF4.21 | Binding site not conserved. | IRON/SULFUR CLUSTER
W.4 | Not in contact with model. | TUNGSTEN ION

    Target    AQGVSRRQLLGRALALGSGAALADLLGPARFLSPAGAATAGAVVPGNPLRVMPDRTWEQIYRNQFEDDSTFVFTCAPNDT
    6sdv.1.A  -MTVTRRHFLKLSAGAAVAGAFT-----------------GLGLSLAPTVARAELQ-----KL--QWA-KQTTSICCYCA

    Target    HNCLLRAHVK---NGVVVRISPTYGYGEATDLYGNRASHRWDPRTCQKGLILSRRFYSERRVKAPMIRKGFKDWVEAGYP
    6sdv.1.A  VGCGLIVHTAKDGQGRAVNVEGD------------PDHPINEGSLCPKGASIFQLGENDQRGTQPLYRAP----------

    Target    RNDDGTPQMDVTLRGSDDWIRISWDEATTIAAKTMEDVARTFNGDEGARKLLAQGYHPEMVEVMHGAGVQALKLRGGMPL
    6sdv.1.A  --------------FSDTWKPVTWDFALTEIAKRIKKTRDASFTEKNAAGDL--VNRTEAIASFG---------------

    Target    LGIGRIFGFYRFANMLALLDRKLRPDAPADEILGSRTFDNYAWHTD--LPPGHPMVTGSQTVDFDLFSAEHTKLLLIIGM
    6sdv.1.A  --------SAAMDNEECWAYGNIL------RSLGLVYIEHQARIUHSPTVPALAESFGRGAMTNHWNDLANSDCILIMGS

    Target    NWICTKMPDGHWIGDARLKGTRVIVISADYMPTANKADEVIILRPGTDAAFFLGVARELIEKGLYDRAAVIERTDLPLLV
    6sdv.1.A  NAAENHPIAFKWVLRAKDKGATLIHVDPRFTRTSARCDVYAPIRSGADIPFLGGLIKYILDNKLYFTDYVREYTNASLIV

    Target    RLDTGERLDARDVIPGYELAALTNYVTLKPDAEIKGNPPPPPFTAGGQVVPTELRDAWGDFVWWDRATGRPRPVSRDEVG
    6sdv.1.A  GEKFS---FKDGLFSGYDAA-N---------------------------------KKYDKS-MWAFE------LD--A--

    Target    ARFDGDPALLGEFEVELVDGSTVPVRPAFDLLKQYLDESFDLRTASEVCRVPPQAIQSIARQLAANK---RETLLAAGMG
    6sdv.1.A  ---------NG---VPKRDPALKHPRCVINLLKKHYE-RYNLDKVAAITGTSKEQLQQVYKAYAATGKPDKAGTIMYAMG

    Target    PNHYFQNDLFGRVQFLVAALTDNIGHLGGNVGSYAGNY--RGSVFQAMGQWIAEDPFAI-EPDLT-------KPATVKRY
    6sdv.1.A  WTQHSVGVQNIRAMAMIQLLLGNIGVAGGGVNALRGESNVQGST--DQGLLAHIWPGYNPVPNSKAATLELYNAATPQSK

    Target    YKAESAHYWNYGER--------------PL---RAVAKDDE-G---DLTKGEVLTGKSHMPTPTKLIWFGNSNSLLGNAK
    6sdv.1.A  DP-MSVNWWQNRPKYVASYLKALYPDEEPAAAYDYLPRIDAGRKLTDYFWLNIFEK--MDKGEFKGLFAWGMNPACGGAN

    Target    WSFDVVKNTLPRQDAVFCNEWHWTSSCEY--------AD-----LVFPADSWAEFKLPDATASCTNPFLLAFPTTPLKRL
    6sdv.1.A  --ANKNRKAMGKLEWLVNVNLFENETSSFWKGPGMNPAEIGTEVFFLPCCVSIEKE--GSV-ANSGRWMQW-RYRGPKPY

    Target    YDTRSDYEALALTAKALGELIDEPRMEQYWRGILDGDPTPYLQRIFSGSNATRGITYDELHESSKRGVPLLMNMRTYPRS
    6sdv.1.A  AETKPDGDIMLDMFKKVRE-------------------------------------------------------------

    Target    GGWEQRQEDKPWYTATGRLEFYRPEPEFQAAGESLPVWREPVDATFYEPNAILSNAAHPSIAPRAPEDYGVPESQLDVET
    6sdv.1.A  --------------------------------------------------------------------------------

    Target    RQYRNVVRTWAELQQTLHPLQERDPAFRFVF
    6sdv.1.A  -------------------------------

### Model #05 | File | Built with | Oligo-State | Ligands | GMQE | QMEANDisCo Global
--- | --- | --- | --- | --- | --- | ---
| PDB | ProMod3 3.2.1 | monomer | 1 x 6MO: MOLYBDENUM(VI) ION; | 0.26 | 0.45 ± 0.05

Template | Seq Identity | Oligo-state | QSQE | Found by | Method | Resolution | Seq Similarity | Range | Coverage | Description
--- | --- | --- | --- | --- | --- | --- | --- | --- | --- | ---
3ir7.1.A | 31.57 | monomer | 0.00 | BLAST | X-ray | 2.50Å | 0.36 | 54 - 630 | 0.54 | Respiratory nitrate reductase 1 alpha chain

### Included Ligands

Ligand | Description
--- | ---
1 x 6MO | MOLYBDENUM(VI) ION

### Excluded ligands

Ligand Name.Number | Reason for Exclusion | Description
--- | --- | ---
AGA.5 | Binding site not conserved. | (1S)-2-{[{[(2S)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PENTANOYLOXY)METHYL]ETHYL OCTANOATE
F3S.9 | Binding site not conserved. | FE3-S4 CLUSTER
HEM.10 | Binding site not conserved. | PROTOPORPHYRIN IX CONTAINING FE
HEM.11 | Binding site not conserved. | PROTOPORPHYRIN IX CONTAINING FE
MD1.1 | Binding site not conserved. | PHOSPHORIC ACID 4-(2-AMINO-4-OXO-3,4,5,6,-TETRAHYDRO-PTERIDIN-6-YL)-2-HYDROXY-3,4-DIMERCAPTO-BUT-3-EN-YL ESTER GUANYLATE ESTER
MD1.2 | Binding site not conserved. | PHOSPHORIC ACID 4-(2-AMINO-4-OXO-3,4,5,6,-TETRAHYDRO-PTERIDIN-6-YL)-2-HYDROXY-3,4-DIMERCAPTO-BUT-3-EN-YL ESTER GUANYLATE ESTER
SF4.3 | Binding site not conserved. | IRON/SULFUR CLUSTER
SF4.6 | Binding site not conserved. | IRON/SULFUR CLUSTER
SF4.7 | Binding site not conserved. | IRON/SULFUR CLUSTER
SF4.8 | Binding site not conserved. | IRON/SULFUR CLUSTER

    Target    AQGVSRRQLLGRALALGSGAALADLLGPARFLSPAGAATAGAVVPGNPLRVMPDRTWEQIYRNQFEDDSTFVFTCAPNDT
    3ir7.1.A  -----------------------------------------------------NRDWEDGYRQRWQHDKIVRSTHGVNCT

    Target    HNCLLRAHVKNGVVVRISPTYGYGEATDLYGNRASHRWDPRTCQKGLILSRRFYSERRVKAPMIRKGF-KDWVEAGYPRN
    3ir7.1.A  GSCSWKIYVKNGLVTWETQQTDYPRTRPDLPNH-----EPRGCPSGASYSWYLYSANRLKYPMMRKRLMKMWREAKALHS

    Target    DDGTPQMDVT-----------LRGSDDWIRISWDEATTIAAKTMEDVARTFNGDEGARKLLAQGYHP--EMVEVMHGAGV
    3ir7.1.A  DPVEAWASIIEDADKAKSFKQARGRGGFVRSSWQEVNELIAASNVYTIKNYGPDRVA------GFSPIPAMSMVSYASGA

    Target    QALKLRGGMPLLGIGRIFGFYRFANMLALLDRKLRPDAPADEILGSRTFDNYAWHTDLPPGHPMVTGSQTVDFDLFSAEH
    3ir7.1.A  RYLSLIGGTCL------------------------------------SF--YDWYCDLPPASPQTWGEQTDVPESADWYN

    Target    TKLLLIIGMNWICTKMPDGHWIGDARLKGTRVIVISADYMPTANKADEVIILRPGTDAAFFLGVARELIEKGLYDRAA--
    3ir7.1.A  SSYIIAWGSNVPQTRTPDAHFFTEVRYKGTKTVAVTPDYAEIAKLCDLWLAPKQGTDAAMALAMGHVMLREFHLDNPSQY

    Target    ----VIERTDLPLLVRLDTGERLDARDVIPGYELAALTNYVTLKPDAEIKGNPP---PPPFTAGGQVVP--TELRDAWGD
    3ir7.1.A  FTDYVRRYTDMPMLVMLE------ERD---GYYAAGRMLRAADLVDALGQENNPEWKTVAFNTNGEMVAPNGSIGFRWGE

    Target    FVWW-----DRATGRPRPV------SRDEVGA----RFDGD-----------PALLGEFEV---ELVDGSTVPVRPAFDL
    3ir7.1.A  KGKWNLEQRDGKTGEETELQLSLLGSQDEIAEVGFPYFGGDGTEHFNKVELENVLLHKLPVKRLQLADGSTALVTTVYDL

    Target    ------LKQYLDE-----SFDLRTA------SEVCRVPPQAIQSIARQLAANKRET----LLAAGMGPNHYFQNDLFGRV
    3ir7.1.A  TLANYGLERGLNDVNCATSYDDVKAYTPAWAEQITGVSRSQIIRIAREFADNADKTHGRSMIIVGAGLNHWYHLDMNYRG

    Target    QFLVAALTDNIGHLGGNVGSYAGNYRGSVFQAMGQWIAEDPFAIEPDLTKPATVKRYYKAESAHYWNYGERPLRAVAKDD
    3ir7.1.A  LINMLIFCGCVGQSGGGWAHYVGQEK---LRPQTGW---QPLAFALDWQRPA---RHMNSTSYFY---------------

    Target    EGDLTKGEVLTGKSHMPTPTKLIWFGNSNSLLGNAKWSFDVVKNTLPRQDAVFCNEWHWTSSCEYADLVFPADSWAEFKL
    3ir7.1.A  --------------------------------------------------------------------------------

    Target    PDATASCTNPFLLAFPTTPLKRLYDTRSDYEALALTAKALGELIDEPRMEQYWRGILDGDPTPYLQRIFSGSNATRGITY
    3ir7.1.A  --------------------------------------------------------------------------------

    Target    DELHESSKRGVPLLMNMRTYPRSGGWEQRQEDKPWYTATGRLEFYRPEPEFQAAGESLPVWREPVDATFYEPNAILSNAA
    3ir7.1.A  --------------------------------------------------------------------------------

    Target    HPSIAPRAPEDYGVPESQLDVETRQYRNVVRTWAELQQTLHPLQERDPAFRFVF
    3ir7.1.A  ------------------------------------------------------

## Materials and Methods

## Template Search

Template search with has been performed against the SWISS-MODEL template library (SMTL, last update: 2023-03-23, last included PDB release: 2023-03-17).

## Template Selection

For each identified template, the template's quality has been predicted from features of the target-template alignment. The templates with the highest quality have then been selected for model building.

## Model Building

Models are built based on the target-template alignment using ProMod3 (Studer et al.). Coordinates which are conserved between the target and the template are copied from the template to the model. Insertions and deletions are remodelled using a fragment library. Side chains are then rebuilt. Finally, the geometry of the resulting model is regularized by using a force field.

## Model Quality Estimation

The global and per-residue model quality has been assessed using the QMEAN scoring function (Studer et al.).

## Ligand Modelling

Ligands present in the template structure are transferred by homology to the model when the following criteria are met: (a) The ligands are annotated as biologically relevant in the template library, (b) the ligand is in contact with the model, (c) the ligand is not clashing with the protein, (d) the residues in contact with the ligand are conserved between the target and the template. If any of these four criteria is not satisfied, a certain ligand will not be included in the model. The model summary includes information on why and which ligand has not been included.

## Oligomeric State Conservation

The quaternary structure annotation of the template is used to model the target sequence in its oligomeric form. The method (Bertoni et al.) is based on a supervised machine learning algorithm, Support Vector Machines (SVM), which combines interface conservation, structural clustering, and other template features to provide a quaternary structure quality estimate (QSQE). The QSQE score is a number between 0 and 1, reflecting the expected accuracy of the interchain contacts for a model built based a given alignment and template. Higher numbers indicate higher reliability. This complements the GMQE score which estimates the accuracy of the tertiary structure of the resulting model.

## References

- BLAST
  Camacho, C., Coulouris, G., Avagyan, V., Ma, N., Papadopoulos, J., Bealer, K., Madden, T.L. BLAST+: architecture and applications. BMC Bioinformatics 10, 421-430 (2009).
- HHblits
  Steinegger, M., Meier, M., Mirdita, M., Vöhringer, H., Haunsberger, S. J., Söding, J. HH-suite3 for fast remote homology detection and deep protein annotation. BMC Bioinformatics 20, 473 (2019).

## Table T1:

Primary amino acid sequence for which templates were searched and models were built.

AQGVSRRQLLGRALALGSGAALADLLGPARFLSPAGAATAGAVVPGNPLRVMPDRTWEQIYRNQFEDDSTFVFTCAPNDTHNCLLRAHVKNGVVVRISPT
YGYGEATDLYGNRASHRWDPRTCQKGLILSRRFYSERRVKAPMIRKGFKDWVEAGYPRNDDGTPQMDVTLRGSDDWIRISWDEATTIAAKTMEDVARTFN
GDEGARKLLAQGYHPEMVEVMHGAGVQALKLRGGMPLLGIGRIFGFYRFANMLALLDRKLRPDAPADEILGSRTFDNYAWHTDLPPGHPMVTGSQTVDFD
LFSAEHTKLLLIIGMNWICTKMPDGHWIGDARLKGTRVIVISADYMPTANKADEVIILRPGTDAAFFLGVARELIEKGLYDRAAVIERTDLPLLVRLDTG
ERLDARDVIPGYELAALTNYVTLKPDAEIKGNPPPPPFTAGGQVVPTELRDAWGDFVWWDRATGRPRPVSRDEVGARFDGDPALLGEFEVELVDGSTVPV
RPAFDLLKQYLDESFDLRTASEVCRVPPQAIQSIARQLAANKRETLLAAGMGPNHYFQNDLFGRVQFLVAALTDNIGHLGGNVGSYAGNYRGSVFQAMGQ
WIAEDPFAIEPDLTKPATVKRYYKAESAHYWNYGERPLRAVAKDDEGDLTKGEVLTGKSHMPTPTKLIWFGNSNSLLGNAKWSFDVVKNTLPRQDAVFCN
EWHWTSSCEYADLVFPADSWAEFKLPDATASCTNPFLLAFPTTPLKRLYDTRSDYEALALTAKALGELIDEPRMEQYWRGILDGDPTPYLQRIFSGSNAT
RGITYDELHESSKRGVPLLMNMRTYPRSGGWEQRQEDKPWYTATGRLEFYRPEPEFQAAGESLPVWREPVDATFYEPNAILSNAAHPSIAPRAPEDYGVP
ESQLDVETRQYRNVVRTWAELQQTLHPLQERDPAFRFVF

## Table T2:

Template | Seq Identity | Oligo-state | QSQE | Found by | Method | Resolution | Seq Similarity | Coverage | Description
--- | --- | --- | --- | --- | --- | --- | --- | --- | ---
7b04.1.B | 41.29 | monomer | - | BLAST | X-ray | 2.97Å | 0.41 | 0.91 | Nitrite oxidoreductase subunit A
7b04.2.B | 41.29 | monomer | - | BLAST | X-ray | 2.97Å | 0.41 | 0.91 | Nitrite oxidoreductase subunit A
7b04.1.B | 39.66 | monomer | - | HHblits | X-ray | 2.97Å | 0.40 | 0.95 | Nitrite oxidoreductase subunit A
7b04.2.B | 39.66 | monomer | - | HHblits | X-ray | 2.97Å | 0.40 | 0.95 | Nitrite oxidoreductase subunit A
5e7o.1.A | 26.60 | monomer | - | HHblits | X-ray | 2.40Å | 0.33 | 0.75 | DMSO reductase family type II enzyme, molybdopterin subunit
4ydd.1.A | 26.60 | monomer | - | HHblits | X-ray | 1.86Å | 0.34 | 0.75 | DMSO reductase family type II enzyme, molybdopterin subunit
2ivf.1.A | 25.73 | monomer | - | HHblits | X-ray | 1.88Å | 0.32 | 0.80 | ETHYLBENZENE DEHYDROGENASE ALPHA-SUBUNIT
4ydd.1.A | 30.14 | monomer | - | BLAST | X-ray | 1.86Å | 0.36 | 0.75 | DMSO reductase family type II enzyme, molybdopterin subunit
5e7o.1.A | 30.14 | monomer | - | BLAST | X-ray | 2.40Å | 0.36 | 0.75 | DMSO reductase family type II enzyme, molybdopterin subunit
3ir5.1.A | 25.36 | monomer | - | HHblits | X-ray | 2.30Å | 0.33 | 0.67 | Respiratory nitrate reductase 1 alpha chain
1q16.1.A | 25.56 | monomer | - | HHblits | X-ray | 1.90Å | 0.33 | 0.67 | Respiratory nitrate reductase 1 alpha chain
1r27.4.A | 24.16 | homo-dimer | 0.19 | HHblits | X-ray | 2.00Å | 0.32 | 0.70 | Respiratory nitrate reductase 1 alpha chain
3ir7.1.A | 24.01 | monomer | - | HHblits | X-ray | 2.50Å | 0.32 | 0.70 | Respiratory nitrate reductase 1 alpha chain
3egw.1.A | 24.84 | homo-dimer | 0.17 | HHblits | X-ray | 1.90Å | 0.32 | 0.67 | Respiratory nitrate reductase 1 alpha chain
3ir6.1.A | 24.20 | monomer | - | HHblits | X-ray | 2.80Å | 0.32 | 0.70 | Respiratory nitrate reductase 1 alpha chain
2iv2.1.A | 20.18 | monomer | - | HHblits | X-ray | 2.27Å | 0.31 | 0.59 | Formate dehydrogenase H
1aa6.1.A | 20.18 | monomer | - | HHblits | X-ray | 2.30Å | 0.31 | 0.59 | FORMATE DEHYDROGENASE H
1e60.1.A | 21.31 | monomer | - | HHblits | X-ray | 2.00Å | 0.30 | 0.65 | Dimethyl sulfoxide/trimethylamine N-oxide reductase
1fdo.1.A | 20.18 | monomer | - | HHblits | X-ray | 2.80Å | 0.31 | 0.59 | FORMATE DEHYDROGENASE H
7z0t.1.G | 20.18 | monomer | - | HHblits | EM | NA | 0.31 | 0.59 | Formate dehydrogenase H
4dmr.1.A | 21.02 | monomer | - | HHblits | X-ray | 1.90Å | 0.30 | 0.65 | DMSO REDUCTASE
1e5v.2.A | 21.55 | monomer | - | HHblits | X-ray | 2.40Å | 0.30 | 0.65 | Dimethyl sulfoxide/trimethylamine N-oxide reductase
6sdv.1.A | 18.11 | monomer | - | HHblits | X-ray | 1.90Å | 0.29 | 0.64 | Formate dehydrogenase, alpha subunit, selenocysteine-containing,Formate dehydrogenase, alpha subunit, selenocysteine-containing,W-formate dehydrogenase - alpha subunit
6sdr.1.A | 18.18 | monomer | - | HHblits | X-ray | 2.10Å | 0.29 | 0.64 | Formate dehydrogenase, alpha subunit, selenocysteine-containing
1e18.1.A | 21.88 | monomer | - | HHblits | X-ray | 2.00Å | 0.30 | 0.65 | DMSO REDUCTASE.
8bqg.1.A | 18.52 | monomer | - | HHblits | X-ray | 1.95Å | 0.29 | 0.60 | Formate dehydrogenase, alpha subunit, selenocysteine-containing
7l5s.1.A | 22.85 | monomer | - | HHblits | X-ray | 2.09Å | 0.31 | 0.55 | Trimethylamine-N-oxide reductase
7l5i.1.A | 22.85 | monomer | - | HHblits | X-ray | 1.73Å | 0.31 | 0.55 | Trimethylamine-N-oxide reductase
2ivf.1.A | 35.66 | monomer | - | BLAST | X-ray | 1.88Å | 0.38 | 0.44 | ETHYLBENZENE DEHYDROGENASE ALPHA-SUBUNIT
3egw.1.A | 31.94 | homo-dimer | 0.09 | BLAST | X-ray | 1.90Å | 0.36 | 0.54 | Respiratory nitrate reductase 1 alpha chain
3ir7.1.A | 31.57 | monomer | - | BLAST | X-ray | 2.50Å | 0.36 | 0.54 | Respiratory nitrate reductase 1 alpha chain
3ir5.1.A | 31.76 | monomer | - | BLAST | X-ray | 2.30Å | 0.36 | 0.54 | Respiratory nitrate reductase 1 alpha chain
1q16.1.A | 31.57 | monomer | - | BLAST | X-ray | 1.90Å | 0.36 | 0.54 | Respiratory nitrate reductase 1 alpha chain
1r27.4.A | 31.57 | homo-dimer | 0.09 | BLAST | X-ray | 2.00Å | 0.36 | 0.54 | Respiratory nitrate reductase 1 alpha chain
3ir6.1.A | 31.57 | monomer | - | BLAST | X-ray | 2.80Å | 0.36 | 0.54 | Respiratory nitrate reductase 1 alpha chain
7nz1.1.E | 18.31 | monomer | - | HHblits | EM | NA | 0.27 | 0.47 | NADH-quinone oxidoreductase subunit G
7p63.1.C | 18.76 | monomer | - | HHblits | EM | NA | 0.28 | 0.47 | NADH-quinone oxidoreductase
7p61.1.C | 18.54 | monomer | - | HHblits | EM | NA | 0.27 | 0.47 | NADH-quinone oxidoreductase
6yj4.1.G | 17.23 | monomer | - | HHblits | EM | NA | 0.29 | 0.44 | Subunit NUAM of NADH:Ubiquinone Oxidoreductase (Complex I)
6rfs.1.A | 17.23 | monomer | - | HHblits | EM | 4.04Å | 0.29 | 0.44 | Subunit NUAM of NADH:Ubiquinone Oxidoreductase (Complex I)
6rfq.1.A | 17.23 | monomer | - | HHblits | EM | 3.30Å | 0.29 | 0.44 | Subunit NUAM of NADH:Ubiquinone Oxidoreductase (Complex I)
6gcs.1.A | 17.23 | monomer | - | HHblits | EM | 4.32Å | 0.29 | 0.44 | 75-KDA PROTEIN (NUAM)
6zk9.1.C | 13.37 | monomer | - | HHblits | EM | NA | 0.27 | 0.45 | NADH:ubiquinone oxidoreductase core subunit S1
7zd6.1.4 | 13.37 | monomer | - | HHblits | EM | NA | 0.27 | 0.45 | NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial
6qc5.1.C | 13.40 | monomer | - | HHblits | EM | NA | 0.27 | 0.45 | NADH:ubiquinone oxidoreductase core subunit S1
6qcf.1.C | 13.40 | monomer | - | HHblits | EM | NA | 0.27 | 0.45 | NADH:ubiquinone oxidoreductase core subunit S1
7qsd.1.G | 13.40 | monomer | - | HHblits | EM | NA | 0.27 | 0.45 | NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial
7vxu.1.L | 13.16 | monomer | - | HHblits | EM | NA | 0.27 | 0.45 | NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial
5o31.1.8 | 13.60 | monomer | - | HHblits | EM | 4.13Å | 0.27 | 0.45 | NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial
7dgr.10.A | 13.60 | monomer | - | HHblits | EM | NA | 0.27 | 0.45 | NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial

The table above shows the top 50 filtered templates. A further 281 templates were found which were considered to be less suitable for modelling than the filtered list.
1aa6.1.A, 1be3.1.E, 1bgy.1.P, 1dms.1.A, 1e18.1.A, 1e5v.2.A, 1e60.1.A, 1eu1.1.A, 1fdo.1.A, 1g8j.1.A, 1g8k.1.A, 1h0h.1.A, 1ici.1.A, 1jeo.1.A, 1kb9.1.E, 1kqf.1.A, 1kqf.1.B, 1l0l.1.E, 1l0n.1.E, 1m2g.1.A, 1m2h.1.A, 1m2j.1.A, 1m2k.1.A, 1m2n.1.A, 1m2n.1.B, 1ma3.1.A, 1ntk.1.E, 1ntm.1.E, 1ogy.1.A, 1q16.1.A, 1q90.1.E, 1r27.4.A, 1s5p.1.A, 1s7g.1.A, 1s7g.1.B, 1s7g.1.C, 1s7g.1.D, 1s7g.1.E, 1sqb.1.E, 1sqp.1.P, 1sqq.1.P, 1sqv.1.E, 1tmo.1.A, 1vf5.1.D, 1vf5.1.L, 1x94.1.A, 1x94.1.B, 1yc5.1.A, 2a3n.1.A, 2b4y.1.A, 2b4y.3.A, 2d2c.1.D, 2d2c.1.L, 2e75.1.D, 2e76.1.D, 2e7z.1.A, 2fug.2.C, 2fyn.1.C, 2fyn.2.C, 2fyu.1.E, 2h2i.1.A, 2h4h.1.A, 2h59.1.B, 2i2w.1.A, 2i2w.2.B, 2iv2.1.A, 2ivf.1.A, 2nya.1.A, 2nyr.1.A, 2nyr.1.B, 2pq4.1.B, 2qjk.1.C, 2qjp.1.C, 2qjy.3.F, 2v3v.1.A, 2v45.1.A, 2vpx.1.D, 2vpz.1.A, 2x3y.1.A, 2ybb.1.b, 3cf4.1.B, 3cwb.1.E, 3egw.1.A, 3etn.1.A, 3eua.1.A, 3fj1.1.A, 3fxa.1.A, 3h1h.1.E, 3h1h.1.O, 3h1i.1.E, 3ir5.1.A, 3ir6.1.A, 3ir7.1.A, 3jr3.1.A, 3jwp.1.A, 3k35.1.A, 3l75.1.E, 3l75.1.O, 3m9s.1.C, 3o5a.1.A, 3pki.1.A, 3riy.2.A, 3sho.1.A, 3sho.1.C, 3u31.1.A, 3zg6.1.A, 4aay.1.A, 4bv2.3.A, 4dmr.1.A, 4g1c.1.A, 4g1c.2.A, 4h44.1.D, 4hda.1.A, 4hda.2.A, 4ivn.1.A, 4nvs.1.A, 4ogq.1.L, 4pv1.1.L, 4twi.1.A, 4twj.1.A, 4u3f.1.E, 4utn.1.A, 4utn.2.A, 4v4c.1.A, 4wd3.1.A, 4ydd.1.A, 5bwl.1.A, 5e7o.1.A, 5gpn.24.A, 5j8k.55.A, 5kkz.1.C, 5kli.1.C, 5klv.1.P, 5lu5.1.A, 5lu6.1.A, 5lu7.1.A, 5mf6.1.A, 5nqd.1.A, 5o31.1.8, 5oj7.1.A, 5ojn.1.A, 5okd.1.E, 5t5i.1.B, 5x16.1.A, 5xhs.1.A, 5xtb.1.L, 5xte.1.C, 5y2f.1.A, 6aco.1.A, 6acp.1.A, 6adq.1.L, 6btm.1.B, 6cz7.1.A, 6enx.1.A, 6eo0.1.A, 6eqs.3.A, 6f0k.1.B, 6fky.1.A, 6fky.2.A, 6flg.1.A, 6g72.1.G, 6gcs.1.A, 6giq.1.E, 6hu9.1.E, 6ljk.1.A, 6ljm.1.A, 6lod.1.B, 6nhg.1.E, 6nin.1.C, 6q8o.1.C, 6q9e.1.E, 6q9e.1.O, 6qbx.15.A, 6qbx.5.A, 6qc2.33.A, 6qc2.43.A, 6qc3.15.A, 6qc3.5.A, 6qc4.15.A, 6qc4.5.A, 6qc5.1.C, 6qcf.1.C, 6rfq.1.A, 6rfs.1.A, 6rxj.1.A, 6rxm.1.A, 6rxm.2.A, 6rxm.3.A, 6rxm.4.A, 6rxm.5.A, 6rxm.6.A, 6rxo.1.A, 6rxo.2.A, 6rxp.2.A, 6rxq.4.A, 6rxs.1.A, 6s6y.1.B, 6sdr.1.A, 6sdv.1.A, 6t0b.1.E, 6t0b.1.O, 6t15.1.E, 6t15.1.O, 6tg9.1.A, 6x89.1.H, 6xvg.3.A, 6yj4.1.G, 6ymx.1.Q, 6ymx.1.Z, 6ziy.1.C, 6zjl.1.C, 6zjn.1.C, 6zjy.1.C, 6zk9.1.C, 6zr2.1.G, 7a23.1.O, 7ak5.1.G, 7ak6.1.G, 7aqr.1.F, 7ar7.1.G, 7ar8.1.G, 7arc.1.F, 7b04.1.B, 7b04.2.B, 7bkb.1.F, 7bkb.1.L, 7cl0.1.A, 7dgr.10.A, 7dgr.60.A, 7dgs.50.A, 7dgs.60.A, 7e1v.1.P, 7e5z.1.A, 7en5.1.A, 7en6.1.A, 7en6.1.B, 7en6.1.C, 7en6.1.D, 7l5i.1.A, 7l5s.1.A, 7nz1.1.E, 7o37.1.E, 7o37.1.O, 7o3c.1.E, 7o3c.1.O, 7o3h.1.E, 7o3h.1.O, 7p61.1.C, 7p63.1.C, 7q5y.1.A, 7qsd.1.G, 7qv7.1.L, 7qv7.1.O, 7r0w.1.L, 7r0w.1.Q, 7rh5.1.V, 7rja.1.H, 7rjb.1.I, 7t2r.1.A, 7t30.1.A, 7tce.2.F, 7tgh.58.A, 7tlj.1.C, 7tz6.1.E, 7tz6.1.P, 7v2c.1.L, 7vw6.1.A, 7vxu.1.L, 7z0t.1.G, 7zd6.1.4, 7zm7.1.I, 7zxy.1.D, 7zxy.1.L, 8asi.1.A, 8asi.1.E, 8asj.1.E, 8b9z.1.G, 8ba0.1.G, 8bqg.1.A, 8e73.55.A, 8e9g.1.G