{"text_format":"3","workbook":"xlsx","n_sheets":1,"sheets":["Table S6"],"read":"whole","date_system":"1900"}

{"sheet":"Table S6","index":0,"n_rows":151,"n_cols":9,"rows_kept":151}
["ID","Description","GeneRatio","BgRatio","pvalue","p.adjust","qvalue","geneID","Count"]
["hsa05215","Prostate cancer","19/118","97/8081",{"v":8.18847555289785e-17,"d":"8.19E-17"},{"v":1.84240699940202e-14,"d":"1.84E-14"},{"v":6.46458596281409e-15,"d":"6.46E-15"},"BCL2/CASP9/PLAU/AR/GSK3B/RELA/GSTP1/EGFR/CCND1/NFKBIA/RAF1/ERBB2/MTOR/CCNE1/MDM2/MAPK1/PIK3CA/IGF1R/FGFR1",19]
["hsa04151","PI3K-Akt signaling pathway","31/118","354/8081",{"v":1.79406710877002e-16,"d":"1.79E-16"},{"v":2.01832549736628e-14,"d":"2.02E-14"},{"v":7.08184385040799e-15,"d":"7.08E-15"},"BCL2/CASP9/GSK3B/RELA/EGFR/VEGFA/CCND1/IL6/RAF1/ERBB2/MYC/NOS3/IGF2/MTOR/MCL1/F2R/JAK2/CCNE1/MET/KDR/MDM2/BCL2L1/MAPK1/JAK3/PIK3CA/NTRK1/CSF1R/FLT1/IGF1R/FGFR1/JAK1",31]
["hsa05167","Kaposi sarcoma-associated herpesvirus infection","24/118","193/8081",{"v":2.81170103781486e-16,"d":"2.81E-16"},{"v":2.10877577836114e-14,"d":"2.11E-14"},{"v":7.39921325740752e-15,"d":"7.40E-15"},"CASP9/CASP3/CASP8/GSK3B/RELA/MAPK8/ICAM1/VEGFA/CCND1/FOS/IL6/NFKBIA/RAF1/HIF1A/MYC/MTOR/PTGS2/JAK2/MAPK14/MAPK1/PIK3CA/JAK1/SRC/TYK2",24]
["hsa01521","EGFR tyrosine kinase inhibitor resistance","17/118","79/8081",{"v":7.21489096108933e-16,"d":"7.21E-16"},{"v":4.05837616561275e-14,"d":"4.06E-14"},{"v":1.4239916370571e-14,"d":"1.42E-14"},"BCL2/GSK3B/EGFR/VEGFA/IL6/RAF1/ERBB2/MTOR/JAK2/MET/KDR/BCL2L1/MAPK1/PIK3CA/IGF1R/JAK1/SRC",17]
["hsa05161","Hepatitis B","21/118","162/8081",{"v":1.07886389652774e-14,"d":"1.08E-14"},{"v":4.64943608396226e-13,"d":"4.65E-13"},{"v":1.63138108209202e-13,"d":"1.63E-13"},"BCL2/CASP9/CASP3/CASP8/RELA/MAPK8/FOS/IL6/NFKBIA/RAF1/MYC/BIRC5/JAK2/CCNE1/MAPK14/MAPK1/JAK3/PIK3CA/JAK1/SRC/TYK2",21]
["hsa05205","Proteoglycans in cancer","23/118","205/8081",{"v":1.23984962238994e-14,"d":"1.24E-14"},{"v":4.64943608396226e-13,"d":"4.65E-13"},{"v":1.63138108209202e-13,"d":"1.63E-13"},"CASP3/PLAU/ESR1/EGFR/VEGFA/CCND1/RAF1/HIF1A/ERBB2/MYC/IGF2/MTOR/ROCK2/MET/KDR/MDM2/MAPK14/MAPK1/PIK3CA/IGF1R/FGFR1/SRC/MMP2",23]
["hsa01522","Endocrine resistance","17/118","98/8081",{"v":3.28776781839343e-14,"d":"3.29E-14"},{"v":1.05678251305503e-12,"d":"1.06E-12"},{"v":3.70800881773695e-13,"d":"3.71E-13"},"BCL2/ESR2/ESR1/MAPK8/EGFR/CCND1/FOS/RAF1/ERBB2/MTOR/MDM2/MAPK14/MAPK1/PIK3CA/IGF1R/SRC/MMP2",17]
["hsa04917","Prolactin signaling pathway","15/118","70/8081",{"v":4.35097715922071e-14,"d":"4.35E-14"},{"v":1.22371232603082e-12,"d":"1.22E-12"},{"v":4.29372745975728e-13,"d":"4.29E-13"},"ESR2/ESR1/GSK3B/RELA/MAPK8/CCND1/FOS/RAF1/TH/CYP17A1/JAK2/MAPK14/MAPK1/PIK3CA/SRC",15]
["hsa05163","Human cytomegalovirus infection","23/118","225/8081",{"v":9.41709440752233e-14,"d":"9.42E-14"},{"v":2.35427360188058e-12,"d":"2.35E-12"},{"v":8.26060912940555e-13,"d":"8.26E-13"},"CASP9/CASP3/CASP8/GSK3B/RELA/EGFR/VEGFA/CCND1/IL6/NFKBIA/RAF1/MYC/PTGER3/MTOR/PTGS2/PTGER2/ROCK2/MDM2/MAPK14/MAPK1/PIK3CA/JAK1/SRC",23]
["hsa04933","AGE-RAGE signaling pathway in diabetic complications","16/118","100/8081",{"v":7.33772402357305e-13,"d":"7.34E-13"},{"v":1.65098790530394e-11,"d":"1.65E-11"},{"v":5.7929400186103e-12,"d":"5.79E-12"},"BCL2/CASP3/RELA/MAPK8/ICAM1/SELE/VCAM1/VEGFA/CCND1/IL6/NOS3/JAK2/MAPK14/MAPK1/PIK3CA/MMP2",16]
["hsa04210","Apoptosis","17/118","136/8081",{"v":8.41363568284497e-12,"d":"8.41E-12"},{"v":1.72097093512738e-10,"d":"1.72E-10"},{"v":6.03849450921887e-11,"d":"6.04E-11"},"BCL2/CASP9/CASP3/CASP8/CTSD/RELA/MAPK8/FOS/NFKBIA/RAF1/BIRC5/MCL1/CTSB/BCL2L1/MAPK1/PIK3CA/NTRK1",17]
["hsa05162","Measles","17/118","139/8081",{"v":1.20398920260619e-11,"d":"1.20E-11"},{"v":2.08382746604918e-10,"d":"2.08E-10"},{"v":7.31167531947079e-11,"d":"7.31E-11"},"BCL2/CASP9/CASP3/CASP8/GSK3B/RELA/MAPK8/CCND1/FOS/IL6/NFKBIA/CCNE1/BCL2L1/JAK3/PIK3CA/JAK1/TYK2",17]
["hsa05418","Fluid shear stress and atherosclerosis","17/118","139/8081",{"v":1.20398920260619e-11,"d":"1.20E-11"},{"v":2.08382746604918e-10,"d":"2.08E-10"},{"v":7.31167531947079e-11,"d":"7.31E-11"},"BCL2/RELA/MAPK8/ICAM1/SELE/VCAM1/GSTP1/GSTM1/VEGFA/FOS/NOS3/NFE2L2/KDR/MAPK14/PIK3CA/SRC/MMP2",17]
["hsa05210","Colorectal cancer","14/118","86/8081",{"v":1.72111642898314e-11,"d":"1.72E-11"},{"v":2.76607997515147e-10,"d":"2.77E-10"},{"v":9.7055437724613e-11,"d":"9.71E-11"},"BCL2/CASP9/CASP3/GSK3B/MAPK8/EGFR/CCND1/FOS/RAF1/MYC/BIRC5/MTOR/MAPK1/PIK3CA",14]
["hsa01524","Platinum drug resistance","13/118","73/8081",{"v":2.89997902501892e-11,"d":"2.90E-11"},{"v":4.08656486136286e-10,"d":"4.09E-10"},{"v":1.43388240749574e-10,"d":"1.43E-10"},"BCL2/CASP9/CASP3/CASP8/GSTP1/GSTM1/ERBB2/BIRC5/TOP2A/MDM2/BCL2L1/MAPK1/PIK3CA",13]
["hsa04659","Th17 cell differentiation","15/118","107/8081",{"v":2.90600167919137e-11,"d":"2.91E-11"},{"v":4.08656486136286e-10,"d":"4.09E-10"},{"v":1.43388240749574e-10,"d":"1.43E-10"},"RELA/MAPK8/AHR/FOS/IL6/NFKBIA/HIF1A/MTOR/RORC/JAK2/MAPK14/MAPK1/JAK3/JAK1/TYK2",15]
["hsa05212","Pancreatic cancer","13/118","76/8081",{"v":4.9493727975758e-11,"d":"4.95E-11"},{"v":6.55064046737974e-10,"d":"6.55E-10"},{"v":2.29847033943149e-10,"d":"2.30E-10"},"CASP9/RELA/MAPK8/EGFR/VEGFA/CCND1/RAF1/ERBB2/MTOR/BCL2L1/MAPK1/PIK3CA/JAK1",13]
["hsa05145","Toxoplasmosis","15/118","112/8081",{"v":5.69359881776825e-11,"d":"5.69E-11"},{"v":7.11699852221031e-10,"d":"7.12E-10"},{"v":2.49719246393344e-10,"d":"2.50E-10"},"BCL2/CASP9/CASP3/CASP8/RELA/MAPK8/ALOX5/NFKBIA/NOS2/JAK2/BCL2L1/MAPK14/MAPK1/JAK1/TYK2",15]
["hsa05219","Bladder cancer","10/118","41/8081",{"v":2.29708897313e-10,"d":"2.30E-10"},{"v":2.72023694186448e-9,"d":"2.72E-09"},{"v":9.54469102408589e-10,"d":"9.54E-10"},"EGFR/VEGFA/CCND1/RAF1/ERBB2/MYC/MDM2/MAPK1/SRC/MMP2",10]
["hsa05224","Breast cancer","16/118","147/8081",{"v":3.01305171180752e-10,"d":"3.01E-10"},{"v":3.38968317578346e-9,"d":"3.39E-09"},{"v":1.18936251781876e-9,"d":"1.19E-09"},"PGR/NCOA1/ESR2/ESR1/GSK3B/EGFR/CCND1/FOS/RAF1/ERBB2/MYC/MTOR/MAPK1/PIK3CA/IGF1R/FGFR1",16]
["hsa04926","Relaxin signaling pathway","15/118","129/8081",{"v":4.41412714574186e-10,"d":"4.41E-10"},{"v":4.70092870001414e-9,"d":"4.70E-09"},{"v":1.64944866667163e-9,"d":"1.65E-09"},"RELA/MAPK8/EGFR/VEGFA/FOS/NFKBIA/RAF1/NOS3/NOS2/MAPK14/MAPK1/PIK3CA/SRC/MMP2/MMP13",15]
["hsa04066","HIF-1 signaling pathway","14/118","109/8081",{"v":4.59646361779161e-10,"d":"4.60E-10"},{"v":4.70092870001414e-9,"d":"4.70E-09"},{"v":1.64944866667163e-9,"d":"1.65E-09"},"BCL2/RELA/EGFR/VEGFA/IL6/HIF1A/ERBB2/NOS3/MTOR/NOS2/MAPK1/PIK3CA/FLT1/IGF1R",14]
["hsa05169","Epstein-Barr virus infection","18/118","202/8081",{"v":5.94252159866357e-10,"d":"5.94E-10"},{"v":5.81333634651871e-9,"d":"5.81E-09"},{"v":2.03976713912937e-9,"d":"2.04E-09"},"BCL2/CASP9/CASP3/CASP8/RELA/MAPK8/ICAM1/CCND1/IL6/NFKBIA/MYC/CCNE1/MDM2/MAPK14/JAK3/PIK3CA/JAK1/TYK2",18]
["hsa04668","TNF signaling pathway","14/118","112/8081",{"v":6.6409270770312e-10,"d":"6.64E-10"},{"v":6.22586913471675e-9,"d":"6.23E-09"},{"v":2.18451548586553e-9,"d":"2.18E-09"},"CASP3/CASP8/RELA/MAPK8/ICAM1/SELE/VCAM1/FOS/IL6/NFKBIA/PTGS2/MAPK14/MAPK1/PIK3CA",14]
["hsa04015","Rap1 signaling pathway","18/118","210/8081",{"v":1.11992674610417e-9,"d":"1.12E-09"},{"v":1.00793407149375e-8,"d":"1.01E-08"},{"v":3.53661077717106e-9,"d":"3.54E-09"},"EGFR/VEGFA/RAF1/CNR1/F2R/MET/KDR/DRD2/ADORA2A/MAPK14/MAPK1/PIK3CA/CSF1R/FLT1/IGF1R/FGFR1/SRC/FPR1",18]
["hsa05225","Hepatocellular carcinoma","16/118","168/8081",{"v":2.20818631599695e-9,"d":"2.21E-09"},{"v":1.91093046576659e-8,"d":"1.91E-08"},{"v":6.7050191781284e-9,"d":"6.71E-09"},"GSK3B/GSTP1/GSTM1/EGFR/CCND1/RAF1/MYC/NFE2L2/IGF2/MTOR/TERT/MET/BCL2L1/MAPK1/PIK3CA/IGF1R",16]
["hsa04913","Ovarian steroidogenesis","10/118","51/8081",{"v":2.31642708547915e-9,"d":"2.32E-09"},{"v":1.93035590456596e-8,"d":"1.93E-08"},{"v":6.77317861251214e-9,"d":"6.77E-09"},"CYP1A1/CYP1B1/ALOX5/AKR1C3/PTGS2/CYP19A1/CYP17A1/HSD17B2/HSD17B1/IGF1R",10]
["hsa05230","Central carbon metabolism in cancer","11/118","70/8081",{"v":4.21204748825048e-9,"d":"4.21E-09"},{"v":3.38468101734414e-8,"d":"3.38E-08"},{"v":1.18760737450672e-8,"d":"1.19E-08"},"EGFR/RAF1/HIF1A/ERBB2/MYC/MTOR/MET/MAPK1/PIK3CA/NTRK1/FGFR1",11]
["hsa05235","PD-L1 expression and PD-1 checkpoint pathway in cancer","12/118","89/8081",{"v":4.92261482908043e-9,"d":"4.92E-09"},{"v":3.81927012601068e-8,"d":"3.82E-08"},{"v":1.34009478105638e-8,"d":"1.34E-08"},"RELA/EGFR/FOS/NFKBIA/RAF1/HIF1A/MTOR/JAK2/MAPK14/MAPK1/PIK3CA/JAK1",12]
["hsa05152","Tuberculosis","16/118","180/8081",{"v":6.05817090584318e-9,"d":"6.06E-09"},{"v":4.54362817938238e-8,"d":"4.54E-08"},{"v":1.59425550153768e-8,"d":"1.59E-08"},"BCL2/CASP9/CASP3/CASP8/CTSD/RELA/MAPK8/IL6/RAF1/NOS2/JAK2/VDR/MAPK14/MAPK1/JAK1/SRC",16]
["hsa04218","Cellular senescence","15/118","156/8081",{"v":6.40031603370471e-9,"d":"6.40E-09"},{"v":4.64539066962439e-8,"d":"4.65E-08"},{"v":1.6299616384647e-8,"d":"1.63E-08"},"RELA/CCND1/IL6/RAF1/MYC/CCNB1/IGFBP3/MTOR/CDC25A/CDK1/CCNE1/MDM2/MAPK14/MAPK1/PIK3CA",15]
["hsa04115","p53 signaling pathway","11/118","73/8081",{"v":6.67697368921148e-9,"d":"6.68E-09"},{"v":4.69474712522682e-8,"d":"4.69E-08"},{"v":1.64727969306204e-8,"d":"1.65E-08"},"BCL2/CASP9/CASP3/CASP8/CCND1/CCNB1/IGFBP3/CDK1/CCNE1/MDM2/BCL2L1",11]
["hsa05222","Small cell lung cancer","12/118","92/8081",{"v":7.25295150709907e-9,"d":"7.25E-09"},{"v":4.94519420938573e-8,"d":"4.95E-08"},{"v":1.73515586294236e-8,"d":"1.74E-08"},"BCL2/CASP9/CASP3/RELA/CCND1/NFKBIA/MYC/PTGS2/NOS2/CCNE1/BCL2L1/PIK3CA",12]
["hsa04657","IL-17 signaling pathway","12/118","94/8081",{"v":9.31533488558625e-9,"d":"9.32E-09"},{"v":6.02594734551007e-8,"d":"6.03E-08"},{"v":2.11436748965266e-8,"d":"2.11E-08"},"CASP3/CASP8/GSK3B/RELA/MAPK8/FOS/IL6/NFKBIA/PTGS2/MAPK14/MAPK1/MMP13",12]
["hsa05170","Human immunodeficiency virus 1 infection","17/118","212/8081",{"v":9.37369587079344e-9,"d":"9.37E-09"},{"v":6.02594734551007e-8,"d":"6.03E-08"},{"v":2.11436748965266e-8,"d":"2.11E-08"},"BCL2/CASP9/CASP3/CASP8/RELA/MAPK8/FOS/NFKBIA/RAF1/CCNB1/MTOR/CDK1/BCL2L1/LIMK1/MAPK14/MAPK1/PIK3CA",17]
["hsa04370","VEGF signaling pathway","10/118","59/8081",{"v":1.0327280457459e-8,"d":"1.03E-08"},{"v":6.4515769214239e-8,"d":"6.45E-08"},{"v":2.26371120049961e-8,"d":"2.26E-08"},"CASP9/VEGFA/RAF1/NOS3/PTGS2/KDR/MAPK14/MAPK1/PIK3CA/SRC",10]
["hsa04915","Estrogen signaling pathway","14/118","138/8081",{"v":1.06092598263415e-8,"d":"1.06E-08"},{"v":6.4515769214239e-8,"d":"6.45E-08"},{"v":2.26371120049961e-8,"d":"2.26E-08"},"BCL2/CTSD/PGR/NCOA1/ESR2/ESR1/EGFR/FOS/RAF1/NOS3/MAPK1/PIK3CA/SRC/MMP2",14]
["hsa00140","Steroid hormone biosynthesis","10/118","61/8081",{"v":1.44641540981125e-8,"d":"1.45E-08"},{"v":8.56430176861922e-8,"d":"8.56E-08"},{"v":3.0050181644278e-8,"d":"3.01E-08"},"CYP3A4/CYP1A1/CYP1B1/AKR1C3/CYP19A1/CYP17A1/HSD17B2/STS/AKR1C1/HSD17B1",10]
["hsa05206","MicroRNAs in cancer","20/118","310/8081",{"v":1.73985432816572e-8,"d":"1.74E-08"},{"v":1.0037621124033e-7,"d":"1.00E-07"},{"v":3.52197232422211e-8,"d":"3.52E-08"},"BCL2/CASP3/PLAU/CYP1B1/EGFR/VEGFA/CCND1/RAF1/ERBB2/MYC/MTOR/CDC25A/PTGS2/MCL1/CCNE1/MET/MDM2/ABCB1/MAPK1/PIK3CA",20]
["hsa04919","Thyroid hormone signaling pathway","13/118","121/8081",{"v":1.83590957386107e-8,"d":"1.84E-08"},{"v":1.03269913529685e-7,"d":"1.03E-07"},{"v":3.62350573788369e-8,"d":"3.62E-08"},"CASP9/NCOA1/ESR1/GSK3B/CCND1/RAF1/HIF1A/MYC/MTOR/MDM2/MAPK1/PIK3CA/SRC",13]
["hsa04914","Progesterone-mediated oocyte maturation","12/118","100/8081",{"v":1.90397444549455e-8,"d":"1.90E-08"},{"v":1.04486402496652e-7,"d":"1.04E-07"},{"v":3.66618956128603e-8,"d":"3.67E-08"},"PGR/MAPK8/RAF1/CCNB1/CDC25A/CDK1/PLK1/MAPK14/MAPK1/PIK3CA/IGF1R/AURKA",12]
["hsa05226","Gastric cancer","14/118","149/8081",{"v":2.85961006650669e-8,"d":"2.86E-08"},{"v":1.52566506378229e-7,"d":"1.53E-07"},{"v":5.35321075011332e-8,"d":"5.35E-08"},"BCL2/GSK3B/EGFR/CCND1/RAF1/ERBB2/MYC/MTOR/TERT/CCNE1/MET/ABCB1/MAPK1/PIK3CA",14]
["hsa04510","Focal adhesion","16/118","201/8081",{"v":2.95509440203742e-8,"d":"2.96E-08"},{"v":1.52566506378229e-7,"d":"1.53E-07"},{"v":5.35321075011332e-8,"d":"5.35E-08"},"BCL2/GSK3B/MAPK8/EGFR/VEGFA/CCND1/RAF1/ERBB2/ROCK2/MET/KDR/MAPK1/PIK3CA/FLT1/IGF1R/SRC",16]
["hsa04625","C-type lectin receptor signaling pathway","12/118","104/8081",{"v":2.98352279139649e-8,"d":"2.98E-08"},{"v":1.52566506378229e-7,"d":"1.53E-07"},{"v":5.35321075011332e-8,"d":"5.35E-08"},"CASP8/RELA/MAPK8/IL6/NFKBIA/RAF1/PTGS2/MDM2/MAPK14/MAPK1/PIK3CA/SRC",12]
["hsa04010","MAPK signaling pathway","19/118","294/8081",{"v":4.03103963113873e-8,"d":"4.03E-08"},{"v":2.01551981556936e-7,"d":"2.02E-07"},{"v":7.07199935287496e-8,"d":"7.07E-08"},"CASP3/RELA/MAPK8/EGFR/VEGFA/FOS/RAF1/ERBB2/MYC/IGF2/MET/KDR/MAPK14/MAPK1/NTRK1/CSF1R/FLT1/IGF1R/FGFR1",19]
["hsa05160","Hepatitis C","14/118","157/8081",{"v":5.5754281105067e-8,"d":"5.58E-08"},{"v":2.72711157579132e-7,"d":"2.73E-07"},{"v":9.56881254663622e-8,"d":"9.57E-08"},"CASP9/CASP3/CASP8/GSK3B/RELA/EGFR/CCND1/NFKBIA/RAF1/MYC/MAPK1/PIK3CA/JAK1/TYK2",14]
["hsa04630","JAK-STAT signaling pathway","14/118","162/8081",{"v":8.29149690510016e-8,"d":"8.29E-08"},{"v":3.96933362478199e-7,"d":"3.97E-07"},{"v":1.39274864027438e-7,"d":"1.39E-07"},"BCL2/EGFR/CCND1/IL6/RAF1/MYC/MTOR/MCL1/JAK2/BCL2L1/JAK3/PIK3CA/JAK1/TYK2",14]
["hsa05202","Transcriptional misregulation in cancer","15/118","192/8081",{"v":1.0635304977278e-7,"d":"1.06E-07"},{"v":4.98529920809905e-7,"d":"4.99E-07"},{"v":1.74922779231546e-7,"d":"1.75E-07"},"PLAU/PPARG/RELA/IL6/MYC/IGFBP3/MET/MDM2/BCL2L1/NTRK1/CSF1R/FLT1/MPO/IGF1R/ELANE",15]
["hsa05213","Endometrial cancer","9/118","58/8081",{"v":1.29744249200387e-7,"d":"1.30E-07"},{"v":5.95764409593613e-7,"d":"5.96E-07"},{"v":2.09040143717057e-7,"d":"2.09E-07"},"CASP9/GSK3B/EGFR/CCND1/RAF1/ERBB2/MYC/MAPK1/PIK3CA",9]
["hsa04014","Ras signaling pathway","16/118","232/8081",{"v":2.18870640988816e-7,"d":"2.19E-07"},{"v":9.84917884449673e-7,"d":"9.85E-07"},{"v":3.4558522261392e-7,"d":"3.46E-07"},"RELA/MAPK8/EGFR/VEGFA/RAF1/IGF2/MET/KDR/BCL2L1/MAPK1/PIK3CA/NTRK1/CSF1R/FLT1/IGF1R/FGFR1",16]
["hsa04215","Apoptosis - multiple species","7/118","32/8081",{"v":2.94532390390427e-7,"d":"2.95E-07"},{"v":1.29940760466365e-6,"d":"1.30E-06"},{"v":4.55932492864438e-7,"d":"4.56E-07"},"BCL2/CASP9/CASP3/CASP8/MAPK8/BIRC5/BCL2L1",7]
["hsa04012","ErbB signaling pathway","10/118","85/8081",{"v":3.74130089789897e-7,"d":"3.74E-07"},{"v":1.61883211928321e-6,"d":"1.62E-06"},{"v":5.68011269923933e-7,"d":"5.68E-07"},"GSK3B/MAPK8/EGFR/RAF1/ERBB2/MYC/MTOR/MAPK1/PIK3CA/SRC",10]
["hsa04068","FoxO signaling pathway","12/118","131/8081",{"v":3.93432763965549e-7,"d":"3.93E-07"},{"v":1.67023343192922e-6,"d":"1.67E-06"},{"v":5.86046818220778e-7,"d":"5.86E-07"},"MAPK8/EGFR/CCND1/IL6/RAF1/CCNB1/MDM2/PLK1/MAPK14/MAPK1/PIK3CA/IGF1R",12]
["hsa05221","Acute myeloid leukemia","9/118","67/8081",{"v":4.66718394413265e-7,"d":"4.67E-07"},{"v":1.94465997672194e-6,"d":"1.94E-06"},{"v":6.82336833937522e-7,"d":"6.82E-07"},"RELA/CCND1/RAF1/MYC/MTOR/MAPK1/PIK3CA/CSF1R/MPO",9]
["hsa05166","Human T-cell leukemia virus 1 infection","15/118","219/8081",{"v":5.91211860218423e-7,"d":"5.91E-07"},{"v":2.41859397362082e-6,"d":"2.42E-06"},{"v":8.48629464428359e-7,"d":"8.49E-07"},"RELA/MAPK8/ICAM1/CCND1/FOS/IL6/NFKBIA/MYC/TERT/CCNE1/BCL2L1/MAPK1/JAK3/PIK3CA/JAK1",15]
["hsa05135","Yersinia infection","12/118","137/8081",{"v":6.40488053897322e-7,"d":"6.40E-07"},{"v":2.57338950226603e-6,"d":"2.57E-06"},{"v":9.02943685005623e-7,"d":"9.03E-07"},"GSK3B/RELA/MAPK8/FOS/IL6/NFKBIA/ROCK2/LIMK1/MAPK14/MAPK1/PIK3CA/SRC",12]
["hsa04658","Th1 and Th2 cell differentiation","10/118","92/8081",{"v":7.91326473731078e-7,"d":"7.91E-07"},{"v":3.12365713314899e-6,"d":"3.12E-06"},{"v":1.09602004671894e-6,"d":"1.10E-06"},"RELA/MAPK8/FOS/NFKBIA/JAK2/MAPK14/MAPK1/JAK3/JAK1/TYK2",10]
["hsa05218","Melanoma","9/118","72/8081",{"v":8.74012054037144e-7,"d":"8.74E-07"},{"v":3.33309681624334e-6,"d":"3.33E-06"},{"v":1.16950765482223e-6,"d":"1.17E-06"},"EGFR/CCND1/RAF1/MET/MDM2/MAPK1/PIK3CA/IGF1R/FGFR1",9]
["hsa05223","Non-small cell lung cancer","9/118","72/8081",{"v":8.74012054037144e-7,"d":"8.74E-07"},{"v":3.33309681624334e-6,"d":"3.33E-06"},{"v":1.16950765482223e-6,"d":"1.17E-06"},"CASP9/EGFR/CCND1/RAF1/ERBB2/MET/MAPK1/JAK3/PIK3CA",9]
["hsa05164","Influenza A","13/118","171/8081",{"v":1.09145562462356e-6,"d":"1.09E-06"},{"v":4.09295859233837e-6,"d":"4.09E-06"},{"v":1.43612582187311e-6,"d":"1.44E-06"},"CASP9/CASP3/CASP8/RELA/ICAM1/IL6/NFKBIA/RAF1/JAK2/MAPK1/PIK3CA/JAK1/TYK2",13]
["hsa04071","Sphingolipid signaling pathway","11/118","119/8081",{"v":1.12602834009201e-6,"d":"1.13E-06"},{"v":4.15338322165085e-6,"d":"4.15E-06"},{"v":1.45732744619328e-6,"d":"1.46E-06"},"BCL2/CTSD/RELA/MAPK8/RAF1/NOS3/ROCK2/ADORA1/MAPK14/MAPK1/PIK3CA",11]
["hsa05220","Chronic myeloid leukemia","9/118","76/8081",{"v":1.3932289219286e-6,"d":"1.39E-06"},{"v":5.05607270054735e-6,"d":"5.06E-06"},{"v":1.77406059668328e-6,"d":"1.77E-06"},"RELA/CCND1/NFKBIA/RAF1/MYC/MDM2/BCL2L1/MAPK1/PIK3CA",9]
["hsa05140","Leishmaniasis","9/118","77/8081",{"v":1.5584814547364e-6,"d":"1.56E-06"},{"v":5.56600519548714e-6,"d":"5.57E-06"},{"v":1.95298427911829e-6,"d":"1.95E-06"},"RELA/FOS/NFKBIA/PTGS2/NOS2/JAK2/MAPK14/MAPK1/JAK1",9]
["hsa04020","Calcium signaling pathway","15/118","240/8081",{"v":1.88799475929213e-6,"d":"1.89E-06"},{"v":6.59428300273777e-6,"d":"6.59E-06"},{"v":2.31378350973255e-6,"d":"2.31E-06"},"EGFR/VEGFA/ERBB2/PTGER3/NOS3/TACR1/NOS2/F2R/MET/KDR/ADORA2A/NTRK1/FLT1/FGFR1/P2RX3",15]
["hsa04080","Neuroactive ligand-receptor interaction","18/118","341/8081",{"v":1.9050150896798e-6,"d":"1.91E-06"},{"v":6.59428300273777e-6,"d":"6.59E-06"},{"v":2.31378350973255e-6,"d":"2.31E-06"},"GABRA1/PTGER3/NR3C1/TACR1/GABRA2/GABRA3/CNR1/PTGER2/F2R/TRPV1/CRHR1/CNR2/DRD2/ADORA1/ADORA2A/P2RX3/FPR1/FPR2",18]
["hsa05142","Chagas disease","10/118","102/8081",{"v":2.06832300873694e-6,"d":"2.07E-06"},{"v":7.05110116614865e-6,"d":"7.05E-06"},{"v":2.47407058461356e-6,"d":"2.47E-06"},"CASP8/RELA/MAPK8/FOS/IL6/NFKBIA/NOS2/MAPK14/MAPK1/PIK3CA",10]
["hsa04380","Osteoclast differentiation","11/118","128/8081",{"v":2.32765010355983e-6,"d":"2.33E-06"},{"v":7.81673542240242e-6,"d":"7.82E-06"},{"v":2.74271418329909e-6,"d":"2.74E-06"},"PPARG/RELA/MAPK8/FOS/NFKBIA/MAPK14/MAPK1/PIK3CA/CSF1R/JAK1/TYK2",11]
["hsa04024","cAMP signaling pathway","14/118","216/8081",{"v":2.78833594808152e-6,"d":"2.79E-06"},{"v":9.22611159291678e-6,"d":"9.23E-06"},{"v":3.23723213786554e-6,"d":"3.24E-06"},"RELA/MAPK8/FOS/NFKBIA/RAF1/PTGER3/PTGER2/F2R/ROCK2/DRD2/ADORA1/ADORA2A/MAPK1/PIK3CA",14]
["hsa04140","Autophagy - animal","11/118","137/8081",{"v":4.53509673187248e-6,"d":"4.54E-06"},{"v":1.47883589082798e-5,"d":"1.48E-05"},{"v":5.18889786255432e-6,"d":"5.19E-06"},"BCL2/CTSD/MAPK8/RAF1/HIF1A/MTOR/CTSB/BCL2L1/MAPK1/PIK3CA/IGF1R",11]
["hsa05130","Pathogenic Escherichia coli infection","13/118","197/8081",{"v":5.32384486747939e-6,"d":"5.32E-06"},{"v":1.71123585026123e-5,"d":"1.71E-05"},{"v":6.00433631670608e-6,"d":"6.00E-06"},"CASP9/CASP3/CASP8/RELA/MAPK8/FOS/IL6/NFKBIA/F2R/ROCK2/MAPK14/MAPK1/SRC",13]
["hsa05165","Human papillomavirus infection","17/118","331/8081",{"v":5.48736121036648e-6,"d":"5.49E-06"},{"v":1.7389524962429e-5,"d":"1.74E-05"},{"v":6.10158770611543e-6,"d":"6.10E-06"},"CASP3/CASP8/GSK3B/RELA/EGFR/VEGFA/CCND1/RAF1/MTOR/PTGS2/TERT/CCNE1/MDM2/MAPK1/PIK3CA/JAK1/TYK2",17]
["hsa04550","Signaling pathways regulating pluripotency of stem cells","11/118","143/8081",{"v":6.8727129587819e-6,"d":"6.87E-06"},{"v":2.14772279961934e-5,"d":"2.15E-05"},{"v":7.53586947234857e-6,"d":"7.54E-06"},"GSK3B/RAF1/MYC/JAK2/MAPK14/MAPK1/JAK3/PIK3CA/IGF1R/FGFR1/JAK1",11]
["hsa05120","Epithelial cell signaling in Helicobacter pylori infection","8/118","70/8081",{"v":7.22613225010833e-6,"d":"7.23E-06"},{"v":2.22723254284161e-5,"d":"2.23E-05"},{"v":7.81485102751442e-6,"d":"7.81E-06"},"CASP3/RELA/MAPK8/EGFR/NFKBIA/MET/MAPK14/SRC",8]
["hsa05203","Viral carcinogenesis","13/118","204/8081",{"v":7.80304049709687e-6,"d":"7.80E-06"},{"v":2.37254609709026e-5,"d":"2.37E-05"},{"v":8.32472314768513e-6,"d":"8.32E-06"},"CASP3/CASP8/RELA/CCND1/NFKBIA/CDK1/CCNE1/MDM2/MAPK1/JAK3/PIK3CA/JAK1/SRC",13]
["hsa04520","Adherens junction","8/118","71/8081",{"v":8.04543071265866e-6,"d":"8.05E-06"},{"v":2.4136292137976e-5,"d":"2.41E-05"},{"v":8.46887443437753e-6,"d":"8.47E-06"},"EGFR/ERBB2/ACP1/MET/MAPK1/IGF1R/FGFR1/SRC",8]
["hsa04722","Neurotrophin signaling pathway","10/118","119/8081",{"v":8.39054098140525e-6,"d":"8.39E-06"},{"v":2.45178145560543e-5,"d":"2.45E-05"},{"v":8.60274194949273e-6,"d":"8.60E-06"},"BCL2/GSK3B/RELA/MAPK8/NFKBIA/RAF1/MAPK14/MAPK1/PIK3CA/NTRK1",10]
["hsa04935","Growth hormone synthesis, secretion and action","10/118","119/8081",{"v":8.39054098140525e-6,"d":"8.39E-06"},{"v":2.45178145560543e-5,"d":"2.45E-05"},{"v":8.60274194949273e-6,"d":"8.60E-06"},"GSK3B/MAPK8/FOS/RAF1/IGFBP3/MTOR/JAK2/MAPK14/MAPK1/PIK3CA",10]
["hsa04621","NOD-like receptor signaling pathway","12/118","181/8081",{"v":1.1948622566546e-5,"d":"1.19E-05"},{"v":3.44671804804212e-5,"d":"3.45E-05"},{"v":1.20937475369899e-5,"d":"1.21E-05"},"BCL2/CASP8/RELA/MAPK8/IL6/NFKBIA/CTSB/BCL2L1/MAPK14/MAPK1/JAK1/TYK2",12]
["hsa05214","Glioma","8/118","75/8081",{"v":1.21532245808515e-5,"d":"1.22E-05"},{"v":3.46136143125517e-5,"d":"3.46E-05"},{"v":1.21451278289655e-5,"d":"1.21E-05"},"EGFR/CCND1/RAF1/MTOR/MDM2/MAPK1/PIK3CA/IGF1R",8]
["hsa05131","Shigellosis","14/118","246/8081",{"v":1.2584575645386e-5,"d":"1.26E-05"},{"v":3.5394119002648e-5,"d":"3.54E-05"},{"v":1.24189891237361e-5,"d":"1.24E-05"},"BCL2/GSK3B/RELA/MAPK8/EGFR/NFKBIA/MTOR/ROCK2/MDM2/BCL2L1/MAPK14/MAPK1/PIK3CA/SRC",14]
["hsa05133","Pertussis","8/118","76/8081",{"v":1.34191064230777e-5,"d":"1.34E-05"},{"v":3.72752956196604e-5,"d":"3.73E-05"},{"v":1.30790510946177e-5,"d":"1.31E-05"},"CASP3/RELA/MAPK8/FOS/IL6/NOS2/MAPK14/MAPK1",8]
["hsa05132","Salmonella infection","14/118","249/8081",{"v":1.44407603532165e-5,"d":"1.44E-05"},{"v":3.96240375545576e-5,"d":"3.96E-05"},{"v":1.39031710717746e-5,"d":"1.39E-05"},"BCL2/CASP3/CASP8/RELA/MAPK8/FOS/IL6/NFKBIA/RAF1/MYC/ROCK2/MAPK14/MAPK1/PIK3CA",14]
["hsa04114","Oocyte meiosis","10/118","129/8081",{"v":1.71593222143094e-5,"d":"1.72E-05"},{"v":4.65162349183087e-5,"d":"4.65E-05"},{"v":1.63214859362487e-5,"d":"1.63E-05"},"PGR/AR/CCNB1/CDK1/CCNE1/PLK1/MAPK14/MAPK1/IGF1R/AURKA",10]
["hsa04620","Toll-like receptor signaling pathway","9/118","104/8081",{"v":1.90914645315802e-5,"d":"1.91E-05"},{"v":5.05362296424181e-5,"d":"5.05E-05"},{"v":1.77320104008484e-5,"d":"1.77E-05"},"CASP8/RELA/MAPK8/FOS/IL6/NFKBIA/MAPK14/MAPK1/PIK3CA",9]
["hsa04660","T cell receptor signaling pathway","9/118","104/8081",{"v":1.90914645315802e-5,"d":"1.91E-05"},{"v":5.05362296424181e-5,"d":"5.05E-05"},{"v":1.77320104008484e-5,"d":"1.77E-05"},"GSK3B/RELA/MAPK8/FOS/NFKBIA/RAF1/MAPK14/MAPK1/PIK3CA",9]
["hsa04931","Insulin resistance","9/118","108/8081",{"v":2.58851391024194e-5,"d":"2.59E-05"},{"v":6.77227476516787e-5,"d":"6.77E-05"},{"v":2.37623675970802e-5,"d":"2.38E-05"},"GSK3B/RELA/MAPK8/IL6/NFKBIA/NOS3/MTOR/ACACB/PIK3CA",9]
["hsa04110","Cell cycle","9/118","124/8081",{"v":7.72629030340628e-5,"d":"7.73E-05"},0.0001998178526743,{"v":7.01115272541405e-5,"d":"7.01E-05"},"GSK3B/CCND1/MYC/CCNB1/CDC25A/CDK1/CCNE1/MDM2/PLK1",9]
["hsa05231","Choline metabolism in cancer","8/118","98/8081",{"v":8.57607580314572e-5,"d":"8.58E-05"},0.000219274665421339,{"v":7.69384790952068e-5,"d":"7.69E-05"},"MAPK8/EGFR/FOS/RAF1/HIF1A/MTOR/MAPK1/PIK3CA",8]
["hsa04064","NF-kappa B signaling pathway","8/118","104/8081",0.000130528726930739,0.000329988354600183,0.000115785387579012,"BCL2/PLAU/RELA/ICAM1/VCAM1/NFKBIA/PTGS2/BCL2L1",8]
["hsa04928","Parathyroid hormone synthesis, secretion and action","8/118","106/8081",0.000149170150670449,0.000372925376676122,0.000130851009360043,"BCL2/EGFR/FOS/RAF1/VDR/MAPK1/FGFR1/MMP13",8]
["hsa05134","Legionellosis","6/118","57/8081",0.000168700772585234,0.000417117294853601,0.000146356945562667,"CASP9/CASP3/CASP8/RELA/IL6/NFKBIA",6]
["hsa04662","B cell receptor signaling pathway","7/118","82/8081",0.000182177254399352,0.000437919638931748,0.000153656013660262,"GSK3B/RELA/FOS/NFKBIA/RAF1/MAPK1/PIK3CA",7]
["hsa05143","African trypanosomiasis","5/118","37/8081",0.000182953093598152,0.000437919638931748,0.000153656013660262,"ICAM1/SELE/VCAM1/IL6/IDO1",5]
["hsa05216","Thyroid cancer","5/118","37/8081",0.000182953093598152,0.000437919638931748,0.000153656013660262,"PPARG/CCND1/MYC/MAPK1/NTRK1",5]
["hsa04723","Retrograde endocannabinoid signaling","9/118","148/8081",0.00029781129417441,0.000705342538834129,0.000247488610117238,"GABRA1/MAPK8/GABRA2/GABRA3/FAAH/PTGS2/CNR1/MAPK14/MAPK1",9]
["hsa04912","GnRH signaling pathway","7/118","93/8081",0.000397828607603097,0.000927369161504988,0.000325392688247364,"MAPK8/EGFR/RAF1/MAPK14/MAPK1/SRC/MMP2",7]
["hsa04921","Oxytocin signaling pathway","9/118","154/8081",0.000399799149626595,0.000927369161504988,0.000325392688247364,"EGFR/CCND1/FOS/RAF1/NOS3/PTGS2/ROCK2/MAPK1/SRC",9]
["hsa04611","Platelet activation","8/118","124/8081",0.000437940926672848,0.00100547661736113,0.000352798813109169,"PTGS1/NOS3/F2R/ROCK2/MAPK14/MAPK1/PIK3CA/SRC",8]
["hsa04664","Fc epsilon RI signaling pathway","6/118","68/8081",0.00044665000306018,0.00101511364331859,0.000356180225725821,"MAPK8/ALOX5/RAF1/MAPK14/MAPK1/PIK3CA",6]
["hsa04062","Chemokine signaling pathway","10/118","192/8081",0.000477515883497719,0.00106639330805022,0.000374173090543938,"GSK3B/RELA/NFKBIA/RAF1/JAK2/ROCK2/MAPK1/JAK3/PIK3CA/SRC",10]
["hsa04920","Adipocytokine signaling pathway","6/118","69/8081",0.000483431632982768,0.00106639330805022,0.000374173090543938,"RELA/MAPK8/NFKBIA/MTOR/JAK2/ACACB",6]
["hsa05211","Renal cell carcinoma","6/118","69/8081",0.000483431632982768,0.00106639330805022,0.000374173090543938,"VEGFA/RAF1/HIF1A/MET/MAPK1/PIK3CA",6]
["hsa04750","Inflammatory mediator regulation of TRP channels","7/118","98/8081",0.000547153258978524,0.0011943718823458,0.000419077853454667,"MAPK8/PTGER2/TRPV1/MAPK14/PIK3CA/NTRK1/SRC",7]
["hsa05171","Coronavirus disease - COVID-19","11/118","232/8081",0.000552065225617615,0.0011943718823458,0.000419077853454667,"RELA/MAPK8/EGFR/FOS/IL6/NFKBIA/MAPK14/MAPK1/PIK3CA/JAK1/TYK2",11]
["hsa05144","Malaria","5/118","50/8081",0.000764631143181142,0.00163849530681673,0.000574910633970783,"ICAM1/SELE/VCAM1/IL6/MET",5]
["hsa00980","Metabolism of xenobiotics by cytochrome P450","6/118","78/8081",0.000931230409412774,0.00197666832186674,0.000693567832233943,"CYP3A4/CYP1A1/CYP1B1/GSTP1/GSTM1/AKR1C1",6]
["hsa05204","Chemical carcinogenesis","6/118","83/8081",0.00128999299787034,0.00271260209832549,0.000951790209938768,"CYP3A4/CYP1A1/CYP1B1/GSTP1/GSTM1/PTGS2",6]
["hsa04923","Regulation of lipolysis in adipocytes","5/118","57/8081",0.00139337150363437,0.00290285729923828,0.00101854642078536,"PTGS1/PTGER3/PTGS2/ADORA1/PIK3CA",5]
["hsa04726","Serotonergic synapse","7/118","115/8081",0.00141379345212361,0.00291838097915423,0.00102399332601903,"PTGS1/CASP3/ALOX5/RAF1/SLC6A4/PTGS2/MAPK1",7]
["hsa04932","Non-alcoholic fatty liver disease","8/118","150/8081",0.00152772320910183,0.00312488838225373,0.00109645206394868,"CASP3/CASP8/GSK3B/RELA/MAPK8/FOS/IL6/PIK3CA",8]
["hsa04540","Gap junction","6/118","88/8081",0.00174605443475428,0.00352662190800021,0.00123741119578955,"EGFR/RAF1/CDK1/DRD2/MAPK1/SRC",6]
["hsa05416","Viral myocarditis","5/118","60/8081",0.00175547401642677,0.00352662190800021,0.00123741119578955,"CASP9/CASP3/CASP8/ICAM1/CCND1",5]
["hsa04152","AMPK signaling pathway","7/118","120/8081",0.00180821728097529,0.00360043263911009,0.00126330969793336,"PPARG/CCND1/MTOR/HMGCR/ACACB/PIK3CA/IGF1R",7]
["hsa04934","Cushing syndrome","8/118","155/8081",0.00188142743076246,0.00369828180106296,0.00129764273721507,"GSK3B/AHR/EGFR/CCND1/CYP17A1/CRHR1/CCNE1/MAPK1",8]
["hsa00590","Arachidonic acid metabolism","5/118","61/8081",0.00189023292054329,0.00369828180106296,0.00129764273721507,"PTGS1/ALOX5/AKR1C3/PTGS2/PTGES",5]
["hsa05010","Alzheimer disease","13/118","369/8081",0.00272754079762557,0.00529048861608407,0.00185631179511722,"CASP9/CASP3/CASP8/GSK3B/RELA/MAPK8/IL6/RAF1/MTOR/PTGS2/NOS2/MAPK1/PIK3CA",13]
["hsa04137","Mitophagy - animal","5/118","68/8081",0.00305489071606637,0.00587478983858917,0.00206132976792602,"RELA/MAPK8/HIF1A/BCL2L1/SRC",5]
["hsa04622","RIG-I-like receptor signaling pathway","5/118","70/8081",0.00346603622388643,0.00660896737605463,0.00231893592142268,"CASP8/RELA/MAPK8/NFKBIA/MAPK14",5]
["hsa05022","Pathways of neurodegeneration - multiple diseases","15/118","475/8081",0.00370478117703915,0.00700483835994797,0.00245783802103438,"BCL2/CASP9/CASP3/CASP8/GSK3B/RELA/MAPK8/IL6/RAF1/MTOR/PTGS2/NOS2/BCL2L1/MAPK14/MAPK1",15]
["hsa04910","Insulin signaling pathway","7/118","137/8081",0.00381684882456974,0.00715659154606826,0.00251108475300641,"GSK3B/MAPK8/RAF1/MTOR/ACACB/MAPK1/PIK3CA",7]
["hsa04930","Type II diabetes mellitus","4/118","46/8081",0.00439450437027123,0.00817159903562833,0.00286722773179941,"MAPK8/MTOR/MAPK1/PIK3CA",4]
["hsa04810","Regulation of actin cytoskeleton","9/118","218/8081",0.0045045735865318,0.00830761522106275,0.00291495270914482,"EGFR/RAF1/F2R/ROCK2/LIMK1/MAPK1/PIK3CA/FGFR1/SRC",9]
["hsa04360","Axon guidance","8/118","182/8081",0.00504966003297976,0.00923718298715809,0.00324111683759933,"GSK3B/RAF1/ROCK2/MET/LIMK1/MAPK1/PIK3CA/SRC",8]
["hsa00983","Drug metabolism - other enzymes","5/118","80/8081",0.00613599147870626,0.0111190020222446,0.00390140421833143,"CYP3A4/GSTP1/GSTM1/MPO/XDH",5]
["hsa00790","Folate biosynthesis","3/118","26/8081",0.00617722334569144,0.0111190020222446,0.00390140421833143,"AKR1B1/AKR1C3/TH",3]
["hsa04670","Leukocyte transendothelial migration","6/118","114/8081",0.0063292823884179,0.0113022899793177,0.00396571578221673,"ICAM1/VCAM1/ROCK2/MAPK14/PIK3CA/MMP2",6]
["hsa04217","Necroptosis","7/118","159/8081",0.00851737707494458,0.0150898412745081,0.00529468114895022,"BCL2/CASP8/MAPK8/JAK2/JAK3/JAK1/TYK2",7]
["hsa04211","Longevity regulating pathway","5/118","89/8081",0.00955481956897846,0.016795581273595,0.0058931864117877,"PPARG/RELA/MTOR/PIK3CA/IGF1R",5]
["hsa04730","Long-term depression","4/118","60/8081",0.0112370632262388,0.0195995288829747,0.00687702767823672,"RAF1/CRHR1/MAPK1/IGF1R",4]
["hsa05323","Rheumatoid arthritis","5/118","93/8081",0.0114278436370308,0.0197789601410149,0.00693998601439119,"ICAM1/VEGFA/FOS/IL6/FLT1",5]
["hsa04728","Dopaminergic synapse","6/118","132/8081",0.012587756184495,0.0216201919199341,0.00758603225260847,"GSK3B/MAPK8/FOS/TH/DRD2/MAPK14",6]
["hsa05168","Herpes simplex virus 1 infection","14/118","498/8081",0.0134222052394611,0.0228787589308996,0.00802763471259636,"BCL2/CASP9/CASP3/CASP8/RELA/IL6/NFKBIA/MTOR/JAK2/BCL2L1/PIK3CA/JAK1/SRC/TYK2",14]
["hsa04929","GnRH secretion","4/118","64/8081",0.0140066422178999,0.0236954473611088,0.00831419205652942,"ESR2/RAF1/MAPK1/PIK3CA",4]
["hsa04371","Apelin signaling pathway","6/118","137/8081",0.0149055333664246,0.0250279478167578,0.00878173607605536,"CCND1/RAF1/NOS3/MTOR/NOS2/MAPK1",6]
["hsa04960","Aldosterone-regulated sodium reabsorption","3/118","37/8081",0.0164397928978862,0.0273390267661292,0.00959264097057164,"NR3C2/MAPK1/PIK3CA",3]
["hsa05146","Amoebiasis","5/118","102/8081",0.0165249228453048,0.0273390267661292,0.00959264097057164,"CASP3/RELA/IL6/NOS2/PIK3CA",5]
["hsa05033","Nicotine addiction","3/118","40/8081",0.0202567233261168,0.033268341229024,0.0116731021856225,"GABRA1/GABRA2/GABRA3",3]
["hsa04072","Phospholipase D signaling pathway","6/118","148/8081",0.0210186796523667,0.0342695863897283,0.0120244162770977,"EGFR/RAF1/MTOR/F2R/MAPK1/PIK3CA",6]
["hsa00380","Tryptophan metabolism","3/118","42/8081",0.0230495104493725,0.0373103586410705,0.0130913539091476,"CYP1A1/CYP1B1/IDO1",3]
["hsa04725","Cholinergic synapse","5/118","113/8081",0.0245694781757754,0.0394866613539247,0.0138549688961139,"BCL2/FOS/JAK2/MAPK1/PIK3CA",5]
["hsa04150","mTOR signaling pathway","6/118","155/8081",0.0256894242537209,0.0409937621070014,0.0143837761778952,"GSK3B/RAF1/MTOR/MAPK1/PIK3CA/IGF1R",6]
["hsa05012","Parkinson disease","8/118","249/8081",0.0290175747312217,0.0459785515107386,0.0161328250914872,"CASP9/CASP3/MAPK8/NFE2L2/TH/BCL2L1/DRD2/ADORA2A",8]
["hsa05030","Cocaine addiction","3/118","49/8081",0.0343861870979121,0.0541041405386729,0.0189839089609379,"RELA/TH/DRD2",3]
["hsa04340","Hedgehog signaling pathway","3/118","50/8081",0.0362024606981269,0.0565663448408233,0.0198478402950257,"BCL2/GSK3B/CCND1",3]
["hsa04742","Taste transduction","4/118","86/8081",0.0367392914619717,0.0570092453720251,0.0200032439901842,"GABRA1/GABRA2/GABRA3/P2RX3",4]
["hsa00220","Arginine biosynthesis","2/118","22/8081",0.0403797283423218,0.062229033404263,0.0218347485628993,"NOS3/NOS2",2]
["hsa04727","GABAergic synapse","4/118","89/8081",0.0408776616961796,0.0625678495349688,0.0219536314157785,"GABRA1/GABRA2/GABRA3/SRC",4]
["hsa04650","Natural killer cell mediated cytotoxicity","5/118","131/8081",0.0424841068299326,0.0645873245725326,0.0226622191482571,"CASP3/ICAM1/RAF1/MAPK1/PIK3CA",5]
["hsa05032","Morphine addiction","4/118","91/8081",0.0437781785680464,0.0661079877705399,0.0231957851826456,"GABRA1/GABRA2/GABRA3/ADORA1",4]
["hsa05020","Prion disease","8/118","273/8081",0.0460234038067574,0.0690351057101361,0.0242228441088197,"CASP9/CASP3/GSK3B/MAPK8/IL6/MAPK14/MAPK1/PIK3CA",8]