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{"sheet":"DAVID-disease high","index":0,"n_rows":806,"n_cols":13,"rows_kept":806,"flags":["formulas_cached_only"]}
["Annotation Cluster 1","Enrichment Score: 31.362065315415393"]
["Category","Term","Count","%","PValue","Genes","List Total","Pop Hits","Pop Total","Fold Enrichment","Bonferroni","Benjamini","FDR"]
["GAD_DISEASE","Inflammation|Premature Birth",64,4.95356037151702,{"v":3.59585019693719e-32,"d":"3.60E-32"},"PTGS2, MMP9, MMP8, CYP2D6, PTGS1, CRP, SLC6A4, ADH1C, TLR2, ADH1B, TLR3, CXCR1, NFKB1, MMP3, MMP2, IL10, MMP1, TGFB1, PGR, PTGES, SERPINE1, IFNG, IL1B, NOS3, FAS, IL1A, PTGER2, PTGER3, CYP1A1, F7, UGT1A1, ADRB2, F2, VEGFA, HSD11B1, COL1A1, TSHR, GSTP1, CCL2, TNF, COL3A1, NFKBIA, CXCL8, NR3C1, POMC, ACE, MTHFR, PAFAH1B1, CYP19A1, PLAT, IL4, IL6, IL2RA, NAT2, IL1RN, CTLA4, IGF1, PLA2G4A, DHFR, PON1, PON2, IGFBP3, IL2, CBS",1181,128,12971,5.49153259949195,{"v":3.94284974094163e-28,"d":"3.94E-28"},{"v":9.38773747843247e-30,"d":"9.39E-30"},{"v":7.40854754263193e-29,"d":"7.41E-29"}]
["GAD_DISEASE","Connective Tissue Diseases|Fetal Diseases|Inflammation|Musculoskeletal Diseases|Pregnancy Complications, Hematologic|Premature Birth|Skin Diseases",64,4.95356037151702,{"v":3.59585019693719e-32,"d":"3.60E-32"},"PTGS2, MMP9, MMP8, CYP2D6, PTGS1, CRP, SLC6A4, ADH1C, TLR2, ADH1B, TLR3, CXCR1, NFKB1, MMP3, MMP2, IL10, MMP1, TGFB1, PGR, PTGES, SERPINE1, IFNG, IL1B, NOS3, FAS, IL1A, PTGER2, PTGER3, CYP1A1, F7, UGT1A1, ADRB2, F2, VEGFA, HSD11B1, COL1A1, TSHR, GSTP1, CCL2, TNF, COL3A1, NFKBIA, CXCL8, NR3C1, POMC, ACE, MTHFR, PAFAH1B1, CYP19A1, PLAT, IL4, IL6, IL2RA, NAT2, IL1RN, CTLA4, IGF1, PLA2G4A, DHFR, PON1, PON2, IGFBP3, IL2, CBS",1181,128,12971,5.49153259949195,{"v":3.94284974094163e-28,"d":"3.94E-28"},{"v":9.38773747843247e-30,"d":"9.39E-30"},{"v":7.40854754263193e-29,"d":"7.41E-29"}]
["GAD_DISEASE","Infection|Inflammation|Premature Birth",63,4.87616099071207,{"v":6.34162959985904e-32,"d":"6.34E-32"},"PTGS2, MMP9, MMP8, CYP2D6, PTGS1, CRP, SLC6A4, ADH1C, TLR2, ADH1B, TLR3, CXCR1, NFKB1, MMP3, MMP2, IL10, MMP1, TGFB1, PGR, PTGES, SERPINE1, IFNG, IL1B, NOS3, FAS, IL1A, PTGER2, PTGER3, CYP1A1, F7, UGT1A1, ADRB2, F2, VEGFA, HSD11B1, COL1A1, TSHR, GSTP1, CCL2, TNF, COL3A1, CXCL8, NR3C1, POMC, ACE, MTHFR, PAFAH1B1, CYP19A1, PLAT, IL4, IL6, IL2RA, NAT2, IL1RN, CTLA4, IGF1, PLA2G4A, DHFR, PON1, PON2, IGFBP3, IL2, CBS",1181,125,12971,5.53546486028789,{"v":6.95359685624543e-28,"d":"6.95E-28"},{"v":1.61711554796405e-29,"d":"1.62E-29"},{"v":1.306569011922e-28,"d":"1.31E-28"}]
[]
["Annotation Cluster 2","Enrichment Score: 13.695264651524573"]
["Category","Term","Count","%","PValue","Genes","List Total","Pop Hits","Pop Total","Fold Enrichment","Bonferroni","Benjamini","FDR"]
["GAD_DISEASE","Bronchiolitis, Viral|Respiratory Syncytial Virus Infections",59,4.56656346749226,{"v":5.92528499958655e-15,"d":"5.93E-15"},"PTGS2, TACR3, EDN1, TLR2, TLR3, IL10, TGFB1, FOS, IFNG, SLC22A4, IL1B, NPSR1, SLC22A5, NOS2, IFNGR2, IL1A, CHUK, ICAM1, CD40, TYK2, ADRB2, CCR5, CD40LG, JUN, IL12B, NGF, CSF2, PRF1, CCL2, TNF, CXCL5, C3, C5, CXCL2, NFKBIA, CXCL8, PF4, CDH1, NR3C1, CCL5, VCAM1, ARG1, TAP1, IL4, IL6, IL2RA, NOS1, TGFBR1, IL1RN, CTLA4, STAT1, STAT3, CD209, IRF1, JAK2, IRF3, ALOX5, IKBKB, IL2",1181,211,12971,3.07109406037938,{"v":6.45200559645786e-11,"d":"6.45E-11"},{"v":4.32986979603811e-13,"d":"4.33E-13"},{"v":1.21236354289067e-11,"d":"1.21E-11"}]
["GAD_DISEASE","Asthma|Bronchiolitis, Viral|Respiratory Syncytial Virus Infections",57,4.41176470588235,{"v":1.87906200665601e-14,"d":"1.88E-14"},"PTGS2, TACR3, EDN1, TLR2, TLR3, IL10, TGFB1, FOS, IFNG, IL1B, NPSR1, NOS2, IFNGR2, CHUK, IL1A, ICAM1, CD40, TYK2, ADRB2, CCR5, CD40LG, CCR2, IL12B, NGF, CSF2, PRF1, CCL2, TNF, CXCL5, C3, C5, CXCL2, NFKBIA, CXCL8, PF4, CDH1, NR3C1, CCL5, VCAM1, ARG1, TAP1, IL4, IL6, IL2RA, NOS1, TGFBR1, IL1RN, CTLA4, STAT1, STAT3, CD209, IRF1, IRF3, JAK2, ALOX5, IKBKB, IL2",1181,204,12971,3.06879762912785,{"v":2.0573376335875e-10,"d":"2.06E-10"},{"v":1.33593136553145e-12,"d":"1.34E-12"},{"v":3.86579657174479e-11,"d":"3.87E-11"}]
["GAD_DISEASE","respiratory syncytial virus bronchiolitis",56,4.3343653250774,{"v":7.37149694116492e-14,"d":"7.37E-14"},"PTGS2, TACR3, EDN1, TLR2, TLR3, IL10, TGFB1, FOS, IFNG, IL1B, NPSR1, NOS2, IFNGR2, CHUK, IL1A, ICAM1, CD40, TYK2, ADRB2, CCR5, CD40LG, JUN, CCR2, NGF, CSF2, PRF1, CCL2, TNF, CXCL5, C3, C5, CXCL2, NFKBIA, CXCL8, PF4, CDH1, NR3C1, CCL5, VCAM1, ARG1, TAP1, IL4, IL6, IL2RA, NOS1, TGFBR1, IL1RN, CTLA4, STAT1, STAT3, CD209, IRF1, IRF3, ALOX5, IKBKB, IL2",1181,204,12971,3.01495907423087,{"v":8.08326738876985e-10,"d":"8.08E-10"},{"v":4.89897011846096e-12,"d":"4.90E-12"},{"v":1.51878509768721e-10,"d":"1.52E-10"}]
[]
["Annotation Cluster 3","Enrichment Score: 12.326247778632998"]
["Category","Term","Count","%","PValue","Genes","List Total","Pop Hits","Pop Total","Fold Enrichment","Bonferroni","Benjamini","FDR"]
["GAD_DISEASE","Coronary Artery Disease|Inflammation",24,1.85758513931888,{"v":1.80560645153944e-14,"d":"1.81E-14"},"IL4, ICAM1, CSF2, SELP, IL6, TNF, CCL2, C3, C5, CTLA4, HP, LTC4S, IL10, TGFB1, VCAM1, ADRB2, CCR5, CCR2, VEGFA, IL1B, NOS3, NOS2, SELE, IL1A",1181,40,12971,6.58983911939034,{"v":1.98429606079741e-10,"d":"1.98E-10"},{"v":1.2969625373671e-12,"d":"1.30E-12"},{"v":3.72812891669127e-11,"d":"3.73E-11"}]
["GAD_DISEASE","Brain Ischemia|Inflammation|Stroke",21,1.62538699690402,{"v":2.34228320481553e-13,"d":"2.34E-13"},"IL4, ICAM1, SELP, CSF2, IL6, TNF, C3, C5, CTLA4, LTC4S, IL10, TGFB1, VCAM1, ADRB2, CCR5, CCR2, IL1B, NOS3, NOS2, SELE, IL1A",1181,33,12971,6.9892233084443,{"v":2.56862864311813e-09,"d":"2.57E-09"},{"v":1.47621914692308e-11,"d":"1.48E-11"},{"v":4.82636153265048e-10,"d":"4.83E-10"}]
["GAD_DISEASE","Chlamydia Infections|Inflammation|Trachoma",20,1.54798761609907,{"v":3.42273433635247e-12,"d":"3.42E-12"},"IL4, ICAM1, SELP, CSF2, IL6, TNF, C3, C5, CTLA4, LTC4S, IL10, TGFB1, ADRB2, CCR5, CCR2, IL1B, NOS3, NOS2, SELE, IL1A",1181,33,12971,6.65640315089934,{"v":3.75299767929604e-08,"d":"3.75E-08"},{"v":1.94455895830003e-10,"d":"1.94E-10"},{"v":7.05181468774185e-09,"d":"7.05E-09"}]
["GAD_DISEASE","Inflammation|Venous Thromboembolism",20,1.54798761609907,{"v":3.42273433635247e-12,"d":"3.42E-12"},"IL4, ICAM1, SELP, CSF2, IL6, TNF, C3, C5, CTLA4, LTC4S, IL10, TGFB1, VCAM1, ADRB2, CCR5, IL1B, NOS3, NOS2, SELE, IL1A",1181,33,12971,6.65640315089934,{"v":3.75299767929604e-08,"d":"3.75E-08"},{"v":1.94455895830003e-10,"d":"1.94E-10"},{"v":7.05181468774185e-09,"d":"7.05E-09"}]
[]
["Annotation Cluster 4","Enrichment Score: 6.704058051835209"]
["Category","Term","Count","%","PValue","Genes","List Total","Pop Hits","Pop Total","Fold Enrichment","Bonferroni","Benjamini","FDR"]
["GAD_DISEASE","Carcinoma, Squamous Cell|Esophageal Neoplasms|Lymphatic Metastasis|Thoracic Neoplasms",11,0.851393188854489,{"v":8.29597653858956e-09,"d":"8.30E-09"},"IL4, IL6, TNF, CRP, IFNG, IL1RN, IL1B, IL12B, TGFB1, IL10, IL2",1181,13,12971,9.29336286067869,{"v":9.0961246268284e-05,"d":"9.10E-05"},{"v":3.2487631684841e-07,"d":"3.25E-07"},{"v":1.70922392461747e-05,"d":"1.71E-05"}]
["GAD_DISEASE","pemphigus vulgaris",12,0.928792569659442,{"v":9.60799900053391e-09,"d":"9.61E-09"},"IL4, HLA-DQB1, IL6, TNF, HLA-DRB1, IFNG, IL1RN, IL1B, TGFB1, IL10, IL1A, IL2",1181,16,12971,8.23729889923793,{"v":0.000105346159718355,"d":"1.05E-04"},{"v":3.69655051013495e-07,"d":"3.70E-07"},{"v":1.9795404815337e-05,"d":"1.98E-05"}]
["GAD_DISEASE","Osteolysis|Prosthesis Failure",10,0.773993808049535,{"v":1.92679826084185e-08,"d":"1.93E-08"},"IL6, TNF, IFNG, IL1RN, IL1B, IL12B, TGFB1, IL10, IL1A, IL2",1181,11,12971,9.98460472634901,{"v":0.000211251115174837,"d":"2.11E-04"},{"v":7.26025275343822e-07,"d":"7.26E-07"},{"v":3.96979103034489e-05,"d":"3.97E-05"}]
["GAD_DISEASE","Scleroderma, Systemic|Skin Ulcer|Systemic Scleroderma",11,0.851393188854489,{"v":2.66579957372112e-08,"d":"2.67E-08"},"IL4, IL6, TNF, IFNG, IL1RN, IL1B, HLA-B, TGFB1, IL10, IL1A, IL2",1181,14,12971,8.62955122777307,{"v":0.00029226220982137,"d":"2.92E-04"},{"v":9.90863667560404e-07,"d":"9.91E-07"},{"v":5.49235830482608e-05,"d":"5.49E-05"}]
["GAD_DISEASE","graft-versus-host disease; longevity; spondyloarthropathies; aphthous stomatitis",10,0.773993808049535,{"v":7.08158593737091e-08,"d":"7.08E-08"},"IL6, TNF, IFNG, IL1RN, CTLA4, IL1B, TGFB1, IL10, IL1A, IL2",1181,12,12971,9.15255433248659,{"v":0.000776194530855423,"d":"7.76E-04"},{"v":2.57117525681582e-06,"d":"2.57E-06"},{"v":0.000145902156167831,"d":"1.46E-04"}]
["GAD_DISEASE","arthritis; asthma; diabetes, type 1; pemphigus; IL-1RI",10,0.773993808049535,{"v":7.08158593737091e-08,"d":"7.08E-08"},"IL4, IL6, TNF, IL1RN, IL1B, IL12B, TGFB1, IL10, IL1A, IL2",1181,12,12971,9.15255433248659,{"v":0.000776194530855423,"d":"7.76E-04"},{"v":2.57117525681582e-06,"d":"2.57E-06"},{"v":0.000145902156167831,"d":"1.46E-04"}]
["GAD_DISEASE","disc disease, intervertebral",9,0.696594427244582,{"v":1.74727294559356e-07,"d":"1.75E-07"},"IL4, IL6, TNF, IFNG, IL1RN, IL1B, IL10, IL1A, IL2",1181,10,12971,9.88475867908552,0.00191405081575457,{"v":6.12101945118848e-06,"d":"6.12E-06"},{"v":0.000359990872988991,"d":"3.60E-04"}]
["GAD_DISEASE","common variable immunodeficiency",11,0.851393188854489,{"v":1.79797506342299e-07,"d":"1.80E-07"},"IL4, IL6, HLA-DRB1, IFNG, IL1RN, IL1B, HLA-B, TGFB1, IL10, IL1A, IL2",1181,16,12971,7.55085732430143,0.00196953774422303,{"v":6.27857848745083e-06,"d":"6.28E-06"},{"v":0.000370437018593072,"d":"3.70E-04"}]
["GAD_DISEASE","desensitization in solid organ transplant recipients ",10,0.773993808049535,{"v":2.11485595874782e-07,"d":"2.11E-07"},"IL4, IL6, TNF, IFNG, IL1RN, IL1B, TGFB1, IL10, IL1A, IL2",1181,13,12971,8.44851169152608,0.00231625314075378,{"v":7.36168656778613e-06,"d":"7.36E-06"},{"v":0.000435723892378003,"d":"4.36E-04"}]
["GAD_DISEASE","Infection|Postoperative Complications",10,0.773993808049535,{"v":2.11485595874782e-07,"d":"2.11E-07"},"IL4, IL6, TNF, IFNG, IL1B, IL12B, TGFB1, IL10, IL1A, IL2",1181,13,12971,8.44851169152608,0.00231625314075378,{"v":7.36168656778613e-06,"d":"7.36E-06"},{"v":0.000435723892378003,"d":"4.36E-04"}]
["GAD_DISEASE","interstitial lung diseases",9,0.696594427244582,{"v":1.62622466017197e-06,"d":"1.63E-06"},"IL4, IL6, TNF, IFNG, IL1RN, TGFB1, IL10, IL1A, IL2",1181,12,12971,8.23729889923793,0.0176735262617776,{"v":5.22906207676143e-05,"d":"5.23E-05"},0.00335046512329739]
["GAD_DISEASE","arthritis; diabetes, type 1; pregnancy loss, recurrent; juvenile arthritis; pemphigus; IL-1RI",8,0.619195046439628,{"v":4.75536529808952e-06,"d":"4.76E-06"},"IL4, TNF, IFNG, IL1B, TGFB1, IL10, IL1A, IL2",1181,10,12971,8.78645215918713,0.0508065969663936,{"v":0.000148968058792386,"d":"1.49E-04"},0.00979704546406612]
["GAD_DISEASE","graft versus host disease",11,0.851393188854489,{"v":5.17426349574667e-06,"d":"5.17E-06"},"IL4, IL6, TNF, CCR5, IFNG, IL1RN, CTLA4, IL1B, TGFB1, IL10, IL1A",1181,21,12971,5.75303415184871,0.0551564738713866,{"v":0.000160712143951302,"d":"1.61E-04"},0.0106600194519912]
["GAD_DISEASE","renal transplantation, rejection after",8,0.619195046439628,{"v":1.20460050152591e-05,"d":"1.20E-05"},"IL4, IL6, TNF, IL1RN, IL1B, TGFB1, IL10, IL1A",1181,11,12971,7.9876837810792,0.123733701519782,{"v":0.000363804992979277,"d":"3.64E-04"},0.024815512286791]
[]
["Annotation Cluster 5","Enrichment Score: 5.759682949982568"]
["Category","Term","Count","%","PValue","Genes","List Total","Pop Hits","Pop Total","Fold Enrichment","Bonferroni","Benjamini","FDR"]
["GAD_DISEASE","Multiple Organ Failure|Multiple Trauma|Sepsis|Systemic infection",8,0.619195046439628,{"v":3.73756514454719e-07,"d":"3.74E-07"},"IL4, IL6, TNF, IFNG, CXCL8, IL1B, IL10, IL1A",1181,8,12971,10.9830651989839,0.00408985461720257,{"v":1.276702425268e-05,"d":"1.28E-05"},{"v":0.000770049532328176,"d":"7.70E-04"}]
["GAD_DISEASE","trypanosomiasis",7,0.541795665634675,{"v":3.61771463940816e-06,"d":"3.62E-06"},"IL4, IL6, TNF, IFNG, CXCL8, IL10, IL1A",1181,7,12971,10.9830651989839,0.0388918264081665,{"v":0.00011464173095399,"d":"1.15E-04"},0.00745333066718423]
["GAD_DISEASE","bullous pemphigoid",9,0.696594427244582,{"v":3.88980716313796e-06,"d":"3.89E-06"},"IL4, IL6, TNF, IFNG, IL1RN, CXCL8, IL1B, IL10, IL1A",1181,13,12971,7.60366052237347,0.041755024835352,{"v":0.000122555186331863,"d":"1.23E-04"},0.00801388295917915]
[]
["Annotation Cluster 6","Enrichment Score: 2.8374751130838476"]
["Category","Term","Count","%","PValue","Genes","List Total","Pop Hits","Pop Total","Fold Enrichment","Bonferroni","Benjamini","FDR"]
["GAD_DISEASE","lymphoproliferative disorders, post-transplant",6,0.464396284829721,{"v":3.42958956475601e-05,"d":"3.43E-05"},"IL6, TNF, IFNG, TGFB1, IL10, IL2",1181,6,12971,10.9830651989839,0.313439510308453,{"v":0.000994375504199562,"d":"9.94E-04"},0.0706362521315284]
["GAD_DISEASE","kidney; failure|Renal Insufficiency",6,0.464396284829721,{"v":3.42958956475601e-05,"d":"3.43E-05"},"IL6, MTHFR, TNF, IFNG, TGFB1, IL10",1181,6,12971,10.9830651989839,0.313439510308453,{"v":0.000994375504199562,"d":"9.94E-04"},0.0706362521315284]
["GAD_DISEASE","lung transplant complications",6,0.464396284829721,{"v":0.000110991348165226,"d":"1.11E-04"},"IL6, TNF, IFNG, ABCB1, TGFB1, IL10",1181,7,12971,9.41405588484335,0.703908774233352,0.0031000005473265,0.228427409218734]
["GAD_DISEASE","graft-vs-host disease",5,0.386996904024767,{"v":0.000316142988028513,"d":"3.16E-04"},"IL6, TNF, IFNG, TGFB1, IL10",1181,5,12971,10.9830651989839,0.96879122380206,0.00846168283503379,0.649336547548296]
["GAD_DISEASE","Hepatitis B|Hepatitis C|Reperfusion Injury",5,0.386996904024767,{"v":0.000316142988028513,"d":"3.16E-04"},"IL6, TNF, IFNG, TGFB1, IL10",1181,5,12971,10.9830651989839,0.96879122380206,0.00846168283503379,0.649336547548296]
["GAD_DISEASE","cell-surface B7 expression; cytokine production",5,0.386996904024767,{"v":0.000316142988028513,"d":"3.16E-04"},"IL6, TNF, IFNG, TGFB1, IL10",1181,5,12971,10.9830651989839,0.96879122380206,0.00846168283503379,0.649336547548296]
["GAD_DISEASE","bronchiolitis obliterans syndrome",5,0.386996904024767,{"v":0.000316142988028513,"d":"3.16E-04"},"IL6, TNF, IFNG, TGFB1, IL10",1181,5,12971,10.9830651989839,0.96879122380206,0.00846168283503379,0.649336547548296]
["GAD_DISEASE","parvovirus B19 infection",5,0.386996904024767,{"v":0.000316142988028513,"d":"3.16E-04"},"IL6, TNF, IFNG, TGFB1, IL10",1181,5,12971,10.9830651989839,0.96879122380206,0.00846168283503379,0.649336547548296]
["GAD_DISEASE","parvovirus",5,0.386996904024767,{"v":0.000316142988028513,"d":"3.16E-04"},"IL6, TNF, IFNG, TGFB1, IL10",1181,5,12971,10.9830651989839,0.96879122380206,0.00846168283503379,0.649336547548296]
["GAD_DISEASE","Chlamydia Infections|Infertility, Female",5,0.386996904024767,{"v":0.000316142988028513,"d":"3.16E-04"},"IL6, TNF, IFNG, TGFB1, IL10",1181,5,12971,10.9830651989839,0.96879122380206,0.00846168283503379,0.649336547548296]
["GAD_DISEASE","Angina Pectoris|Coronary Artery Disease|Inflammation|Myocardial Infarction",5,0.386996904024767,{"v":0.000316142988028513,"d":"3.16E-04"},"IL6, TNF, IFNG, TGFB1, IL10",1181,5,12971,10.9830651989839,0.96879122380206,0.00846168283503379,0.649336547548296]
["GAD_DISEASE","hepatitis C infection",5,0.386996904024767,{"v":0.000316142988028513,"d":"3.16E-04"},"IL6, TNF, IFNG, TGFB1, IL10",1181,5,12971,10.9830651989839,0.96879122380206,0.00846168283503379,0.649336547548296]
["GAD_DISEASE","allograft outcome",5,0.386996904024767,{"v":0.000316142988028513,"d":"3.16E-04"},"IL6, TNF, IFNG, TGFB1, IL10",1181,5,12971,10.9830651989839,0.96879122380206,0.00846168283503379,0.649336547548296]
["GAD_DISEASE","kidney graft survival",5,0.386996904024767,{"v":0.000316142988028513,"d":"3.16E-04"},"IL6, TNF, IFNG, TGFB1, IL10",1181,5,12971,10.9830651989839,0.96879122380206,0.00846168283503379,0.649336547548296]
["GAD_DISEASE","renal transplantation, protein secretion in",5,0.386996904024767,{"v":0.000316142988028513,"d":"3.16E-04"},"IL4, IL6, TNF, IFNG, IL10",1181,5,12971,10.9830651989839,0.96879122380206,0.00846168283503379,0.649336547548296]
["GAD_DISEASE","renal allograft outcome",5,0.386996904024767,{"v":0.000879837172786953,"d":"8.80E-04"},"IL6, TNF, IFNG, TGFB1, IL10",1181,6,12971,9.15255433248659,0.999935681365791,0.022506221462588,1.7971851943858]
["GAD_DISEASE","leukemia, acute myeloid; longevity; myelodysplasia",4,0.309597523219814,0.00280003722742694,"IL6, TNF, IFNG, IL10",1181,4,12971,10.9830651989839,0.999999999999955,0.0669034123884211,5.61331953178421]
["GAD_DISEASE","Clonorchiasis|Fibrosis",4,0.309597523219814,0.00280003722742694,"TNF, IFNG, TGFB1, IL10",1181,4,12971,10.9830651989839,0.999999999999955,0.0669034123884211,5.61331953178421]
["GAD_DISEASE","cardiomyopathy; heart anomalies, congenital",4,0.309597523219814,0.00280003722742694,"TNF, IFNG, TGFB1, IL10",1181,4,12971,10.9830651989839,0.999999999999955,0.0669034123884211,5.61331953178421]
["GAD_DISEASE","Alphavirus Infections|Infectious Mononucleosis|Q Fever",4,0.309597523219814,0.00280003722742694,"IL6, TNF, IFNG, IL10",1181,4,12971,10.9830651989839,0.999999999999955,0.0669034123884211,5.61331953178421]
["GAD_DISEASE","allograft dysfunction, renal",4,0.309597523219814,0.00280003722742694,"IL6, TNF, TGFB1, IL10",1181,4,12971,10.9830651989839,0.999999999999955,0.0669034123884211,5.61331953178421]
["GAD_DISEASE","Common Cold|Otitis Media|Picornaviridae Infections",4,0.309597523219814,0.00280003722742694,"IL6, TNF, IFNG, IL10",1181,4,12971,10.9830651989839,0.999999999999955,0.0669034123884211,5.61331953178421]
["GAD_DISEASE","Common Cold|",4,0.309597523219814,0.00280003722742694,"IL6, TNF, IFNG, IL10",1181,4,12971,10.9830651989839,0.999999999999955,0.0669034123884211,5.61331953178421]
["GAD_DISEASE","Autoimmune Diseases|Pelvic Pain|Prostatitis|Syndrome",4,0.309597523219814,0.00280003722742694,"IL6, TNF, TGFB1, IL10",1181,4,12971,10.9830651989839,0.999999999999955,0.0669034123884211,5.61331953178421]
["GAD_DISEASE","Alveolitis, Extrinsic Allergic|Bird Fancier's Lung|Extrinsic allergic alveolitis",4,0.309597523219814,0.00280003722742694,"IL6, TNF, TGFB1, IL10",1181,4,12971,10.9830651989839,0.999999999999955,0.0669034123884211,5.61331953178421]
["GAD_DISEASE","HIV; tuberculosis; cleft lip with cleft palate; cleft lip without cleft palate",5,0.386996904024767,0.00590940530146925,"IL6, TNF, IFNG, IL10, IL1A",1181,9,12971,6.10170288832439,1,0.133647341411972,11.4951582898578]
["GAD_DISEASE","Hodgkin Disease|Lymphoma|Lymphoma, Non-Hodgkin",5,0.386996904024767,0.00590940530146925,"IL4, IL6, TNF, IFNG, IL10",1181,9,12971,6.10170288832439,1,0.133647341411972,11.4951582898578]
["GAD_DISEASE","preterm birth",5,0.386996904024767,0.00590940530146925,"PGR, IL6, TNF, IFNG, IL10",1181,9,12971,6.10170288832439,1,0.133647341411972,11.4951582898578]
["GAD_DISEASE","Brucellosis|",4,0.309597523219814,0.00652587858657671,"IL6, TNF, TGFB1, IL10",1181,5,12971,8.78645215918713,1,0.145374045255921,12.6191139188296]
["GAD_DISEASE","Epstein-Barr Virus Infections|Lymphoproliferative Disorders",4,0.309597523219814,0.00652587858657671,"TNF, IFNG, TGFB1, IL10",1181,5,12971,8.78645215918713,1,0.145374045255921,12.6191139188296]
["GAD_DISEASE","Endotoxemia",4,0.309597523219814,0.0198721362964792,"IL6, TNF, IFNG, IL10",1181,7,12971,6.27603725656223,1,0.370216045027357,33.870112521485]
["GAD_DISEASE","Neovascularization, Pathologic|Retinal Vasculitis",3,0.23219814241486,0.0233063975432453,"TNF, IFNG, IL10",1181,3,12971,10.9830651989839,1,0.415192508197618,38.4836377101908]
["GAD_DISEASE","Boutonneuse Fever|",3,0.23219814241486,0.0233063975432453,"TNF, IFNG, IL10",1181,3,12971,10.9830651989839,1,0.415192508197618,38.4836377101908]
["GAD_DISEASE","carotid plaque",3,0.23219814241486,0.0438127578581207,"IL6, TNF, IFNG",1181,4,12971,8.23729889923793,1,0.630065979941808,60.2693790825589]
["GAD_DISEASE","SARS (severe acute respiratory syndrome)",3,0.23219814241486,0.0969200560616097,"TNF, IFNG, IL10",1181,6,12971,5.49153259949195,1,0.88780434582701,87.7587799802275]
[]
["Annotation Cluster 7","Enrichment Score: 2.5634505390099678"]
["Category","Term","Count","%","PValue","Genes","List Total","Pop Hits","Pop Total","Fold Enrichment","Bonferroni","Benjamini","FDR"]
["GAD_DISEASE","Constriction, Pathologic|Graft Occlusion, Vascular",5,0.386996904024767,{"v":0.000879837172786953,"d":"8.80E-04"},"MMP9, MMP3, MMP2, MMP1, TIMP1",1181,6,12971,9.15255433248659,0.999935681365791,0.022506221462588,1.7971851943858]
["GAD_DISEASE","Coronary Disease|Coronary heart disease|Diabetic Angiopathies|Myocardial Infarction",5,0.386996904024767,0.00190496493893241,"MMP9, MMP3, MMP2, MMP1, TIMP1",1181,7,12971,7.84504657070279,0.999999999168559,0.0466134493640447,3.85238462728602]
["GAD_DISEASE","Carotid Artery Diseases|Carotid artery stenosis|Carotid Stenosis|Hypertension",4,0.309597523219814,0.0121719200005317,"MMP9, MMP3, MMP2, MMP1",1181,6,12971,7.32204346598927,1,0.250825117332743,22.3001907789742]
[]
["Annotation Cluster 8","Enrichment Score: 2.4926964286415485"]
["Category","Term","Count","%","PValue","Genes","List Total","Pop Hits","Pop Total","Fold Enrichment","Bonferroni","Benjamini","FDR"]
["GAD_DISEASE","hyperhomocystinemia",5,0.386996904024767,{"v":0.000879837172786953,"d":"8.80E-04"},"MTHFR, MTR, NOS3, CBS, MTRR",1181,6,12971,9.15255433248659,0.999935681365791,0.022506221462588,1.7971851943858]
["GAD_DISEASE","1-carbon metabolism",6,0.464396284829721,0.00614828801379998,"MTHFR, DHFR, MTR, NOS3, CBS, MTRR",1181,14,12971,4.70702794242167,1,0.137826210302817,11.9323125139768]
["GAD_DISEASE","Heart Defects, Congenital|Spinal Dysraphism",6,0.464396284829721,0.00614828801379998,"MTHFR, DHFR, MTR, NOS3, CBS, MTRR",1181,14,12971,4.70702794242167,1,0.137826210302817,11.9323125139768]
[]
["Annotation Cluster 9","Enrichment Score: 2.4722070700482255"]
["Category","Term","Count","%","PValue","Genes","List Total","Pop Hits","Pop Total","Fold Enrichment","Bonferroni","Benjamini","FDR"]
["GAD_DISEASE","Hepatitis C|Hepatitis C, Chronic|Substance Abuse, Intravenous|Viremia",6,0.464396284829721,{"v":3.42958956475601e-05,"d":"3.43E-05"},"HLA-DQB1, HLA-DRB1, HLA-A, HLA-C, HLA-B, HLA-DQA1",1181,6,12971,10.9830651989839,0.313439510308453,{"v":0.000994375504199562,"d":"9.94E-04"},0.0706362521315284]
["GAD_DISEASE","cytokine resposne",6,0.464396284829721,{"v":0.000110991348165226,"d":"1.11E-04"},"HLA-DQB1, HLA-DRB1, HLA-A, HLA-C, HLA-B, HLA-DQA1",1181,7,12971,9.41405588484335,0.703908774233352,0.0031000005473265,0.228427409218734]
["GAD_DISEASE","Arthritis, Psoriatic|Psoriasis",6,0.464396284829721,{"v":0.000110991348165226,"d":"1.11E-04"},"HLA-DRB1, HLA-A, HLA-C, HLA-B, IL12B, HLA-DQA1",1181,7,12971,9.41405588484335,0.703908774233352,0.0031000005473265,0.228427409218734]
["GAD_DISEASE","keloids",6,0.464396284829721,{"v":0.000110991348165226,"d":"1.11E-04"},"HLA-DQB1, HLA-DRB1, HLA-A, HLA-C, HLA-B, HLA-DQA1",1181,7,12971,9.41405588484335,0.703908774233352,0.0031000005473265,0.228427409218734]
["GAD_DISEASE","Multiple Sclerosis|Neuromyelitis Optica",6,0.464396284829721,{"v":0.000110991348165226,"d":"1.11E-04"},"HLA-DQB1, HLA-DRB1, HLA-A, HLA-C, HLA-B, HLA-DQA1",1181,7,12971,9.41405588484335,0.703908774233352,0.0031000005473265,0.228427409218734]
["GAD_DISEASE","Dengue",6,0.464396284829721,{"v":0.000273727613421708,"d":"2.74E-04"},"HLA-DQB1, TNF, HLA-DRB1, HLA-A, HLA-C, HLA-B",1181,8,12971,8.23729889923793,0.950304164510716,0.00740274622441139,0.562451808804609]
["GAD_DISEASE","Asthma|Occupational Diseases",6,0.464396284829721,{"v":0.000273727613421708,"d":"2.74E-04"},"HLA-DQB1, HLA-DRB1, HLA-A, HLA-C, HLA-B, HLA-DQA1",1181,8,12971,8.23729889923793,0.950304164510716,0.00740274622441139,0.562451808804609]
["GAD_DISEASE","rubella vaccine response",6,0.464396284829721,{"v":0.000273727613421708,"d":"2.74E-04"},"HLA-DQB1, HLA-DRB1, HLA-A, HLA-C, HLA-B, HLA-DQA1",1181,8,12971,8.23729889923793,0.950304164510716,0.00740274622441139,0.562451808804609]
["GAD_DISEASE","Spondylarthritis",6,0.464396284829721,{"v":0.000273727613421708,"d":"2.74E-04"},"HLA-DRB1, TNC, HLA-A, HLA-C, HLA-B, HLA-DQA1",1181,8,12971,8.23729889923793,0.950304164510716,0.00740274622441139,0.562451808804609]
["GAD_DISEASE","psoriasis; celiac disease",5,0.386996904024767,{"v":0.000316142988028513,"d":"3.16E-04"},"HLA-DQB1, HLA-DRB1, HLA-A, HLA-C, HLA-B",1181,5,12971,10.9830651989839,0.96879122380206,0.00846168283503379,0.649336547548296]
["GAD_DISEASE","HIV; cytomegalovirus retinitis",5,0.386996904024767,{"v":0.000316142988028513,"d":"3.16E-04"},"HLA-DQB1, HLA-DRB1, HLA-A, HLA-B, HLA-DQA1",1181,5,12971,10.9830651989839,0.96879122380206,0.00846168283503379,0.649336547548296]
["GAD_DISEASE","Eye Diseases|Stevens-Johnson Syndrome",5,0.386996904024767,{"v":0.000316142988028513,"d":"3.16E-04"},"HLA-DQB1, HLA-DRB1, HLA-A, HLA-C, HLA-B",1181,5,12971,10.9830651989839,0.96879122380206,0.00846168283503379,0.649336547548296]
["GAD_DISEASE","hepatitis C sicca syndrome",5,0.386996904024767,{"v":0.000316142988028513,"d":"3.16E-04"},"HLA-DQB1, HLA-DRB1, HLA-A, HLA-C, HLA-B",1181,5,12971,10.9830651989839,0.96879122380206,0.00846168283503379,0.649336547548296]
["GAD_DISEASE","arthrofibrosis",5,0.386996904024767,{"v":0.000316142988028513,"d":"3.16E-04"},"HLA-DQB1, HLA-DRB1, HLA-A, HLA-C, HLA-B",1181,5,12971,10.9830651989839,0.96879122380206,0.00846168283503379,0.649336547548296]
["GAD_DISEASE","Hemoglobinuria, Paroxysmal",5,0.386996904024767,{"v":0.000316142988028513,"d":"3.16E-04"},"HLA-DQB1, HLA-DRB1, HLA-A, HLA-C, HLA-B",1181,5,12971,10.9830651989839,0.96879122380206,0.00846168283503379,0.649336547548296]
["GAD_DISEASE","Bronchiectasis|Respiratory Tract Infections",5,0.386996904024767,{"v":0.000316142988028513,"d":"3.16E-04"},"HLA-DQB1, HLA-DRB1, HLA-A, HLA-B, HLA-DQA1",1181,5,12971,10.9830651989839,0.96879122380206,0.00846168283503379,0.649336547548296]
["GAD_DISEASE","Rheumatic Diseases|Spondylitis, Ankylosing",5,0.386996904024767,{"v":0.000316142988028513,"d":"3.16E-04"},"HLA-DRB1, HLA-A, HLA-C, HLA-B, HLA-DQA1",1181,5,12971,10.9830651989839,0.96879122380206,0.00846168283503379,0.649336547548296]
["GAD_DISEASE","Inflammation|Myositis",5,0.386996904024767,{"v":0.000316142988028513,"d":"3.16E-04"},"HLA-DRB1, HLA-A, HLA-C, HLA-B, HLA-DQA1",1181,5,12971,10.9830651989839,0.96879122380206,0.00846168283503379,0.649336547548296]
["GAD_DISEASE","Graft vs Host Disease|Leukemia|Recurrence",5,0.386996904024767,{"v":0.000316142988028513,"d":"3.16E-04"},"HLA-DQB1, HLA-DRB1, HLA-A, HLA-C, HLA-B",1181,5,12971,10.9830651989839,0.96879122380206,0.00846168283503379,0.649336547548296]
["GAD_DISEASE","stem cell transplantation outcome",5,0.386996904024767,{"v":0.000316142988028513,"d":"3.16E-04"},"HLA-DQB1, HLA-DRB1, HLA-A, HLA-C, HLA-B",1181,5,12971,10.9830651989839,0.96879122380206,0.00846168283503379,0.649336547548296]
["GAD_DISEASE","pegylated interferon/ribavirin therapy",5,0.386996904024767,{"v":0.000316142988028513,"d":"3.16E-04"},"HLA-DQB1, HLA-DRB1, HLA-A, HLA-C, HLA-B",1181,5,12971,10.9830651989839,0.96879122380206,0.00846168283503379,0.649336547548296]
["GAD_DISEASE","Chronic ulcerative colitis|Colitis, Ulcerative|Crohn Disease|Crohn's disease|Pregnancy Complications",5,0.386996904024767,{"v":0.000316142988028513,"d":"3.16E-04"},"HLA-DRB1, HLA-A, HLA-C, HLA-B, HLA-DQA1",1181,5,12971,10.9830651989839,0.96879122380206,0.00846168283503379,0.649336547548296]
["GAD_DISEASE","Autoimmune Diseases|Myositis",5,0.386996904024767,{"v":0.000316142988028513,"d":"3.16E-04"},"HLA-DRB1, HLA-A, HLA-C, HLA-B, HLA-DQA1",1181,5,12971,10.9830651989839,0.96879122380206,0.00846168283503379,0.649336547548296]
["GAD_DISEASE","alveolar echinococcosis",5,0.386996904024767,{"v":0.000316142988028513,"d":"3.16E-04"},"HLA-DQB1, HLA-DRB1, HLA-A, HLA-C, HLA-B",1181,5,12971,10.9830651989839,0.96879122380206,0.00846168283503379,0.649336547548296]
["GAD_DISEASE","alveolitis, extrinsic allergic",5,0.386996904024767,{"v":0.000316142988028513,"d":"3.16E-04"},"HLA-DQB1, HLA-DRB1, HLA-A, HLA-C, HLA-B",1181,5,12971,10.9830651989839,0.96879122380206,0.00846168283503379,0.649336547548296]
["GAD_DISEASE","multiple sclerosis; optic neuritis",5,0.386996904024767,{"v":0.000316142988028513,"d":"3.16E-04"},"HLA-DQB1, HLA-DRB1, HLA-A, HLA-B, HLA-DQA1",1181,5,12971,10.9830651989839,0.96879122380206,0.00846168283503379,0.649336547548296]
["GAD_DISEASE","Bites and Stings|BITES STINGS|Hypersensitivity",5,0.386996904024767,{"v":0.000316142988028513,"d":"3.16E-04"},"HLA-DQB1, HLA-DRB1, HLA-A, HLA-C, HLA-B",1181,5,12971,10.9830651989839,0.96879122380206,0.00846168283503379,0.649336547548296]
["GAD_DISEASE","Birth Weight|Diabetes Mellitus, Type 1",5,0.386996904024767,{"v":0.000316142988028513,"d":"3.16E-04"},"HLA-DQB1, HLA-DRB1, HLA-A, HLA-B, HLA-DQA1",1181,5,12971,10.9830651989839,0.96879122380206,0.00846168283503379,0.649336547548296]
["GAD_DISEASE","HIV Infections|Lipodystrophy|[X]Human immunodeficiency virus disease",5,0.386996904024767,{"v":0.000879837172786953,"d":"8.80E-04"},"HLA-DQB1, HLA-DRB1, HLA-A, HLA-C, HLA-B",1181,6,12971,9.15255433248659,0.999935681365791,0.022506221462588,1.7971851943858]
["GAD_DISEASE","Exanthema|HIV Infections",5,0.386996904024767,{"v":0.000879837172786953,"d":"8.80E-04"},"HLA-DQB1, HLA-DRB1, HLA-A, HLA-C, HLA-B",1181,6,12971,9.15255433248659,0.999935681365791,0.022506221462588,1.7971851943858]
["GAD_DISEASE","Hepatitis, Autoimmune|Liver Cirrhosis",5,0.386996904024767,{"v":0.000879837172786953,"d":"8.80E-04"},"HLA-DQB1, HLA-DRB1, HLA-A, HLA-C, HLA-B",1181,6,12971,9.15255433248659,0.999935681365791,0.022506221462588,1.7971851943858]
["GAD_DISEASE","Hemophilia A|Hemophilia B",5,0.386996904024767,{"v":0.000879837172786953,"d":"8.80E-04"},"HLA-DQB1, HLA-DRB1, HLA-A, HLA-C, HLA-B",1181,6,12971,9.15255433248659,0.999935681365791,0.022506221462588,1.7971851943858]
["GAD_DISEASE","Graft vs Host Disease|Leukemia|Leukemia, Myeloid|Precursor Cell Lymphoblastic Leukemia-Lymphoma",5,0.386996904024767,{"v":0.000879837172786953,"d":"8.80E-04"},"HLA-DQB1, HLA-DRB1, HLA-A, HLA-C, HLA-B",1181,6,12971,9.15255433248659,0.999935681365791,0.022506221462588,1.7971851943858]
["GAD_DISEASE","pancreatitis, autoimmune; pancreatitis, chronic calcifying",5,0.386996904024767,{"v":0.000879837172786953,"d":"8.80E-04"},"HLA-DQB1, HLA-DRB1, HLA-A, HLA-C, HLA-B",1181,6,12971,9.15255433248659,0.999935681365791,0.022506221462588,1.7971851943858]
["GAD_DISEASE","graft-versus-host disease; psoriasis; celiac disease",5,0.386996904024767,{"v":0.000879837172786953,"d":"8.80E-04"},"HLA-DQB1, HLA-DRB1, HLA-A, HLA-C, HLA-B",1181,6,12971,9.15255433248659,0.999935681365791,0.022506221462588,1.7971851943858]
["GAD_DISEASE","Plasmodium falciparum infection",5,0.386996904024767,{"v":0.000879837172786953,"d":"8.80E-04"},"HLA-DQB1, HLA-DRB1, HLA-A, HLA-B, HLA-DQA1",1181,6,12971,9.15255433248659,0.999935681365791,0.022506221462588,1.7971851943858]
["GAD_DISEASE","celiac disease; Wegener's granulomatosis; cervical cancer",6,0.464396284829721,0.00105415266009241,"HLA-DQB1, HLA-DRB1, HLA-A, HLA-C, HLA-B, HLA-DQA1",1181,10,12971,6.58983911939034,0.999990506285066,0.0265366193728522,2.14958135384006]
["GAD_DISEASE","HLA genes",4,0.309597523219814,0.00280003722742694,"HLA-DQB1, HLA-DRB1, HLA-A, HLA-B",1181,4,12971,10.9830651989839,0.999999999999955,0.0669034123884211,5.61331953178421]
["GAD_DISEASE","variable age at onset disease",4,0.309597523219814,0.00280003722742694,"CD36, HLA-DRB1, HLA-A, HLA-B",1181,4,12971,10.9830651989839,0.999999999999955,0.0669034123884211,5.61331953178421]
["GAD_DISEASE","Eye Infections, Fungal|Fungal eye infections|Histoplasmosis|Neovascularization, Pathologic",4,0.309597523219814,0.00280003722742694,"HLA-DRB1, HLA-A, HLA-B, HLA-DQA1",1181,4,12971,10.9830651989839,0.999999999999955,0.0669034123884211,5.61331953178421]
["GAD_DISEASE","Acquired Immunodeficiency Syndrome|Tuberculosis, Pulmonary",4,0.309597523219814,0.00280003722742694,"HLA-DQB1, HLA-DRB1, HLA-A, HLA-B",1181,4,12971,10.9830651989839,0.999999999999955,0.0669034123884211,5.61331953178421]
["GAD_DISEASE","leukemia lymphoma",4,0.309597523219814,0.00280003722742694,"HLA-DQB1, HLA-DRB1, HLA-A, HLA-B",1181,4,12971,10.9830651989839,0.999999999999955,0.0669034123884211,5.61331953178421]
["GAD_DISEASE","Tuberculosis, Osteoarticular",4,0.309597523219814,0.00280003722742694,"HLA-DQB1, HLA-DRB1, HLA-A, HLA-B",1181,4,12971,10.9830651989839,0.999999999999955,0.0669034123884211,5.61331953178421]
["GAD_DISEASE","neuropathy, small fiber",4,0.309597523219814,0.00280003722742694,"HLA-DQB1, HLA-DRB1, HLA-A, HLA-B",1181,4,12971,10.9830651989839,0.999999999999955,0.0669034123884211,5.61331953178421]
["GAD_DISEASE","Epidermal Necrolysis, Toxic|Stevens-Johnson Syndrome|Toxic Epidermal Necrolysis",4,0.309597523219814,0.00280003722742694,"HLA-DRB1, HLA-A, HLA-C, HLA-B",1181,4,12971,10.9830651989839,0.999999999999955,0.0669034123884211,5.61331953178421]
["GAD_DISEASE","Cyclophosphamide",4,0.309597523219814,0.00280003722742694,"HLA-DRB1, HLA-A, HLA-C, HLA-B",1181,4,12971,10.9830651989839,0.999999999999955,0.0669034123884211,5.61331953178421]
["GAD_DISEASE","Autoimmune Diseases|Cholangitis, Sclerosing",4,0.309597523219814,0.00280003722742694,"HLA-DRB1, HLA-A, HLA-C, HLA-B",1181,4,12971,10.9830651989839,0.999999999999955,0.0669034123884211,5.61331953178421]
["GAD_DISEASE","Paraneoplastic Syndromes, Nervous System|Small cell carcinoma of lung|Small Cell Lung Carcinoma",4,0.309597523219814,0.00280003722742694,"HLA-DQB1, HLA-DRB1, HLA-A, HLA-B",1181,4,12971,10.9830651989839,0.999999999999955,0.0669034123884211,5.61331953178421]
["GAD_DISEASE","Drug Hypersensitivity|HIV Infections",4,0.309597523219814,0.00280003722742694,"HLA-DQB1, HLA-DRB1, HLA-C, HLA-B",1181,4,12971,10.9830651989839,0.999999999999955,0.0669034123884211,5.61331953178421]
["GAD_DISEASE","Drug Toxicity|Epidermal Necrolysis, Toxic|Stevens-Johnson Syndrome|Toxic Epidermal Necrolysis",4,0.309597523219814,0.00280003722742694,"HLA-DRB1, HLA-A, HLA-C, HLA-B",1181,4,12971,10.9830651989839,0.999999999999955,0.0669034123884211,5.61331953178421]
["GAD_DISEASE","Autoimmune Diseases|Retroperitoneal Fibrosis",4,0.309597523219814,0.00280003722742694,"TNF, HLA-DRB1, HLA-A, HLA-B",1181,4,12971,10.9830651989839,0.999999999999955,0.0669034123884211,5.61331953178421]
["GAD_DISEASE","Hantavirus Infections",4,0.309597523219814,0.00280003722742694,"HLA-DQB1, HLA-DRB1, HLA-A, HLA-B",1181,4,12971,10.9830651989839,0.999999999999955,0.0669034123884211,5.61331953178421]
["GAD_DISEASE","Pigeon breeders disease",4,0.309597523219814,0.00280003722742694,"HLA-DQB1, HLA-DRB1, HLA-A, HLA-B",1181,4,12971,10.9830651989839,0.999999999999955,0.0669034123884211,5.61331953178421]
["GAD_DISEASE","Hypersensitivity|Skin Diseases",4,0.309597523219814,0.00280003722742694,"HLA-DRB1, HLA-A, HLA-C, HLA-B",1181,4,12971,10.9830651989839,0.999999999999955,0.0669034123884211,5.61331953178421]
["GAD_DISEASE","Anemia|Kidney Diseases|Red-Cell Aplasia, Pure",4,0.309597523219814,0.00280003722742694,"HLA-DQB1, HLA-DRB1, HLA-A, HLA-B",1181,4,12971,10.9830651989839,0.999999999999955,0.0669034123884211,5.61331953178421]
["GAD_DISEASE","Complex Regional Pain Syndromes|Dystonia|",4,0.309597523219814,0.00280003722742694,"HLA-DQB1, HLA-DRB1, HLA-A, HLA-B",1181,4,12971,10.9830651989839,0.999999999999955,0.0669034123884211,5.61331953178421]
["GAD_DISEASE","myositis, sporadic inclusion-body",4,0.309597523219814,0.00280003722742694,"HLA-DQB1, HLA-DRB1, HLA-A, HLA-B",1181,4,12971,10.9830651989839,0.999999999999955,0.0669034123884211,5.61331953178421]
["GAD_DISEASE","diabetes, type 2; alveolitis, extrinsic allergic",4,0.309597523219814,0.00280003722742694,"HLA-DQB1, HLA-DRB1, HLA-A, HLA-B",1181,4,12971,10.9830651989839,0.999999999999955,0.0669034123884211,5.61331953178421]
["GAD_DISEASE","pityriasis rosea",5,0.386996904024767,0.00353620226448439,"HLA-DQB1, HLA-DRB1, HLA-A, HLA-C, HLA-B",1181,8,12971,6.86441574936494,1,0.0834075328662788,7.03858472337265]
["GAD_DISEASE","infection, post allograft",5,0.386996904024767,0.00590940530146925,"HLA-DQB1, HLA-DRB1, HLA-A, HLA-B, HLA-DQA1",1181,9,12971,6.10170288832439,1,0.133647341411972,11.4951582898578]
["GAD_DISEASE","Dengue|Dengue Fever",4,0.309597523219814,0.00652587858657671,"HLA-DRB1, HLA-A, HLA-C, HLA-B",1181,5,12971,8.78645215918713,1,0.145374045255921,12.6191139188296]
["GAD_DISEASE","nut allergy",4,0.309597523219814,0.00652587858657671,"HLA-DQB1, HLA-DRB1, HLA-A, HLA-B",1181,5,12971,8.78645215918713,1,0.145374045255921,12.6191139188296]
["GAD_DISEASE","Addison Disease|Addison's disease|Autoimmune Diseases",4,0.309597523219814,0.00652587858657671,"HLA-DQB1, HLA-DRB1, HLA-A, HLA-B",1181,5,12971,8.78645215918713,1,0.145374045255921,12.6191139188296]
["GAD_DISEASE","Anemia, Aplastic|Aplastic anemia|Genetic Diseases, Inborn|Graft vs Host Disease|Hematologic Neoplasms|Recurrence",4,0.309597523219814,0.00652587858657671,"TNF, HLA-DRB1, HLA-A, HLA-B",1181,5,12971,8.78645215918713,1,0.145374045255921,12.6191139188296]
["GAD_DISEASE","HTLV-I Infections|Paraparesis, Tropical Spastic|Tropical Spastic Paraparesis",4,0.309597523219814,0.00652587858657671,"HLA-DRB1, HLA-A, HLA-C, HLA-B",1181,5,12971,8.78645215918713,1,0.145374045255921,12.6191139188296]
["GAD_DISEASE","leukemia, chronic lymphocytic",4,0.309597523219814,0.0121719200005317,"HLA-DQB1, HLA-DRB1, BAX, HLA-B",1181,6,12971,7.32204346598927,1,0.250825117332743,22.3001907789742]
["GAD_DISEASE","aplastic anemia",4,0.309597523219814,0.0121719200005317,"HLA-DRB1, IFNG, HLA-A, HLA-B",1181,6,12971,7.32204346598927,1,0.250825117332743,22.3001907789742]
["GAD_DISEASE","HIV Infections|Tuberculosis, Pulmonary",4,0.309597523219814,0.0121719200005317,"HLA-DQB1, HLA-DRB1, HLA-A, HLA-B",1181,6,12971,7.32204346598927,1,0.250825117332743,22.3001907789742]
["GAD_DISEASE","Abortion, Habitual|Abruptio Placentae|PLACENTA ABRUPTIO",4,0.309597523219814,0.0198721362964792,"HLA-DQB1, HLA-DRB1, HLA-A, HLA-B",1181,7,12971,6.27603725656223,1,0.370216045027357,33.870112521485]
["GAD_DISEASE","Autoimmune Diseases",7,0.541795665634675,0.0219546582229215,"HLA-DQB1, HLA-DRB1, HLA-A, HLA-C, HLA-B, TREH, HLA-DQA1",1181,25,12971,3.07525825571549,1,0.398406175378617,36.7055276651614]
["GAD_DISEASE","Aortic Aneurysm, Abdominal|Aortic Diseases|Arterial Occlusive Diseases",3,0.23219814241486,0.0233063975432453,"HLA-DRB1, HLA-A, HLA-B",1181,3,12971,10.9830651989839,1,0.415192508197618,38.4836377101908]
["GAD_DISEASE","Herpes Zoster|Neuralgia",3,0.23219814241486,0.0233063975432453,"HLA-DRB1, HLA-A, HLA-B",1181,3,12971,10.9830651989839,1,0.415192508197618,38.4836377101908]
["GAD_DISEASE","organ donation",3,0.23219814241486,0.0233063975432453,"HLA-DRB1, HLA-A, HLA-B",1181,3,12971,10.9830651989839,1,0.415192508197618,38.4836377101908]
["GAD_DISEASE","Hepatitis B, Chronic|Remission, Spontaneous",3,0.23219814241486,0.0233063975432453,"HLA-DRB1, HLA-A, HLA-B",1181,3,12971,10.9830651989839,1,0.415192508197618,38.4836377101908]
["GAD_DISEASE","Rheumatoid spondylitis|Spondylarthritis|Spondylitis, Ankylosing",3,0.23219814241486,0.0233063975432453,"HLA-DRB1, HLA-A, HLA-B",1181,3,12971,10.9830651989839,1,0.415192508197618,38.4836377101908]
["GAD_DISEASE","Cryptosporidiosis|Recurrence",3,0.23219814241486,0.0233063975432453,"HLA-DQB1, HLA-DRB1, HLA-B",1181,3,12971,10.9830651989839,1,0.415192508197618,38.4836377101908]
["GAD_DISEASE","Cholangitis, Sclerosing|Inflammatory bowel disease, NOS|Inflammatory Bowel Diseases|Liver Cirrhosis",3,0.23219814241486,0.0233063975432453,"HLA-DRB1, HLA-C, HLA-B",1181,3,12971,10.9830651989839,1,0.415192508197618,38.4836377101908]
["GAD_DISEASE","Brain Neoplasms|Hemangioma, Cavernous, Central Nervous System",3,0.23219814241486,0.0233063975432453,"HLA-DRB1, HLA-A, HLA-B",1181,3,12971,10.9830651989839,1,0.415192508197618,38.4836377101908]
["GAD_DISEASE","Heart Failure|Raeder-Harbitz syndrome|Takayasu Arteritis",3,0.23219814241486,0.0233063975432453,"HLA-DRB1, HLA-A, HLA-B",1181,3,12971,10.9830651989839,1,0.415192508197618,38.4836377101908]
["GAD_DISEASE","Graft vs Host Disease|Leukemia, Myeloid, Acute|Precursor Cell Lymphoblastic Leukemia-Lymphoma",3,0.23219814241486,0.0233063975432453,"HLA-DRB1, HLA-A, HLA-B",1181,3,12971,10.9830651989839,1,0.415192508197618,38.4836377101908]
["GAD_DISEASE","Pars Planitis",3,0.23219814241486,0.0233063975432453,"HLA-DRB1, HLA-A, HLA-B",1181,3,12971,10.9830651989839,1,0.415192508197618,38.4836377101908]
["GAD_DISEASE","Lupus Erythematosus, Cutaneous|Photosensitivity Disorders",3,0.23219814241486,0.0233063975432453,"HLA-DRB1, HLA-A, HLA-B",1181,3,12971,10.9830651989839,1,0.415192508197618,38.4836377101908]
["GAD_DISEASE","Anemia, Aplastic|Aplastic anemia|Hemoglobinuria, Paroxysmal",3,0.23219814241486,0.0233063975432453,"HLA-DRB1, HLA-A, HLA-B",1181,3,12971,10.9830651989839,1,0.415192508197618,38.4836377101908]
["GAD_DISEASE","Diabetes mellitus|Polycystic Kidney, Autosomal Dominant",3,0.23219814241486,0.0233063975432453,"HLA-DRB1, HLA-A, HLA-B",1181,3,12971,10.9830651989839,1,0.415192508197618,38.4836377101908]
["GAD_DISEASE","glomeruloneophritis",3,0.23219814241486,0.0233063975432453,"HLA-DRB1, HLA-A, HLA-B",1181,3,12971,10.9830651989839,1,0.415192508197618,38.4836377101908]
["GAD_DISEASE","human papilloma virus/HPV",3,0.23219814241486,0.0233063975432453,"HLA-DQB1, HLA-DRB1, HLA-B",1181,3,12971,10.9830651989839,1,0.415192508197618,38.4836377101908]
["GAD_DISEASE","Mycobacterium avium-intracellulare Infection|Respiratory Tract Infections",3,0.23219814241486,0.0233063975432453,"HLA-DRB1, HLA-A, HLA-B",1181,3,12971,10.9830651989839,1,0.415192508197618,38.4836377101908]
["GAD_DISEASE","Kaposi's sarcoma",4,0.309597523219814,0.0296736967160852,"HLA-DQB1, HLA-DRB1, TP53, HLA-B",1181,8,12971,5.49153259949195,1,0.493902162431577,46.2390556747162]
["GAD_DISEASE","Anemia, Aplastic",4,0.309597523219814,0.0296736967160852,"HLA-DQB1, HLA-DRB1, HLA-A, HLA-B",1181,8,12971,5.49153259949195,1,0.493902162431577,46.2390556747162]
["GAD_DISEASE","Paraparesis, Tropical Spastic|Tropical Spastic Paraparesis",6,0.464396284829721,0.0301434618340041,"HLA-DQB1, HLA-DRB1, HLA-A, HLA-C, HLA-B, IL10",1181,20,12971,3.29491955969517,1,0.497988122715935,46.7727613307007]
["GAD_DISEASE","herpes-associated recurrent lymphocytic meningitis",3,0.23219814241486,0.0438127578581207,"HLA-DRB1, HLA-A, HLA-B",1181,4,12971,8.23729889923793,1,0.630065979941808,60.2693790825589]
["GAD_DISEASE","pulmonary hypertension; thrombosis, deep vein; pulmonary thromboembolism",3,0.23219814241486,0.0438127578581207,"HLA-DRB1, HLA-A, HLA-B",1181,4,12971,8.23729889923793,1,0.630065979941808,60.2693790825589]
["GAD_DISEASE","Chlamydophila Infections|Coronary Artery Disease",3,0.23219814241486,0.0438127578581207,"HLA-DRB1, HLA-A, HLA-B",1181,4,12971,8.23729889923793,1,0.630065979941808,60.2693790825589]
["GAD_DISEASE","acute coronary syndrome atherosclerosis, coronary cholesterol, LDL smoking behavior",3,0.23219814241486,0.0686706773740773,"HLA-DRB1, HLA-A, HLA-B",1181,5,12971,6.58983911939034,1,0.788585717782312,76.9095009968113]
["GAD_DISEASE","Hypertension, Pulmonary|Thromboembolism|Venous Thrombosis",3,0.23219814241486,0.0686706773740773,"HLA-DRB1, HLA-A, HLA-B",1181,5,12971,6.58983911939034,1,0.788585717782312,76.9095009968113]
["GAD_DISEASE","Churg-Strauss Syndrome",3,0.23219814241486,0.0686706773740773,"HLA-DRB1, HLA-A, HLA-B",1181,5,12971,6.58983911939034,1,0.788585717782312,76.9095009968113]
["GAD_DISEASE","Graft vs Host Disease|Leukemia, Myeloid, Acute",5,0.386996904024767,0.0878181528399496,"HLA-DQB1, HLA-DRB1, HLA-A, HLA-C, HLA-B",1181,19,12971,2.89028031552208,1,0.862478148700338,84.9493354434928]
["GAD_DISEASE","Drug Hypersensitivity|Urticaria",3,0.23219814241486,0.0969200560616097,"HLA-DRB1, HLA-C, HLA-B",1181,6,12971,5.49153259949195,1,0.88780434582701,87.7587799802275]
["GAD_DISEASE","respiratory papillomatosis",5,0.386996904024767,0.11765965205057,"HLA-DQB1, HLA-DRB1, HLA-A, HLA-C, HLA-B",1181,21,12971,2.61501552356759,1,0.930773417468566,92.4152940404794]
["GAD_DISEASE","polyangiitis",3,0.23219814241486,0.127739223966434,"HLA-DQB1, HLA-DRB1, HLA-B",1181,7,12971,4.70702794242167,1,0.945205773685763,94.0140408904238]
["GAD_DISEASE","diffuse panbonchiolitis",3,0.23219814241486,0.127739223966434,"HLA-DRB1, HLA-A, HLA-B",1181,7,12971,4.70702794242167,1,0.945205773685763,94.0140408904238]
["GAD_DISEASE","Graft vs Host Disease|Leukemia|Leukemia, Myeloid|Myeloid Leukemia|Neoplasm Recurrence, Local",4,0.309597523219814,0.196937406078181,"HLA-DRB1, HLA-A, HLA-C, HLA-B",1181,17,12971,2.58425063505503,1,0.989207999414521,98.9096969491623]
[]
["Annotation Cluster 10","Enrichment Score: 2.306297078301377"]
["Category","Term","Count","%","PValue","Genes","List Total","Pop Hits","Pop Total","Fold Enrichment","Bonferroni","Benjamini","FDR"]
["GAD_DISEASE","noncardia gastric cancer",5,0.386996904024767,{"v":0.000316142988028513,"d":"3.16E-04"},"IL4, IL6, TNF, IL1B, IL10",1181,5,12971,10.9830651989839,0.96879122380206,0.00846168283503379,0.649336547548296]
["GAD_DISEASE","Inflammation|Inflammatory bowel disease, NOS|Inflammatory Bowel Diseases",5,0.386996904024767,{"v":0.000316142988028513,"d":"3.16E-04"},"IL6, TNF, IL1RN, IL1B, IL10",1181,5,12971,10.9830651989839,0.96879122380206,0.00846168283503379,0.649336547548296]
["GAD_DISEASE","bacterial vaginosis",5,0.386996904024767,{"v":0.000879837172786953,"d":"8.80E-04"},"IL6, TNF, CXCL8, IL1B, IL10",1181,6,12971,9.15255433248659,0.999935681365791,0.022506221462588,1.7971851943858]
["GAD_DISEASE","Atrial Fibrillation|Inflammation",5,0.386996904024767,{"v":0.000879837172786953,"d":"8.80E-04"},"IL6, TNF, IL1B, IL10, IL1A",1181,6,12971,9.15255433248659,0.999935681365791,0.022506221462588,1.7971851943858]
["GAD_DISEASE","leukopenia neutropenia stomatitis thrombocytopenia",5,0.386996904024767,0.00190496493893241,"IL6, TNF, IL1RN, IL1B, IL10",1181,7,12971,7.84504657070279,0.999999999168559,0.0466134493640447,3.85238462728602]
["GAD_DISEASE","asthma; lipids; C-reactive protein; obesity; glucose; leptin; atopy",4,0.309597523219814,0.00280003722742694,"IL6, TNF, IL1B, IL10",1181,4,12971,10.9830651989839,0.999999999999955,0.0669034123884211,5.61331953178421]
["GAD_DISEASE","Aortic Aneurysm, Abdominal|Aortic Rupture",4,0.309597523219814,0.00280003722742694,"IL6, TNF, IL1B, IL10",1181,4,12971,10.9830651989839,0.999999999999955,0.0669034123884211,5.61331953178421]
["GAD_DISEASE","Aneurysm, Ruptured|Aortic Aneurysm, Abdominal",4,0.309597523219814,0.00280003722742694,"IL6, TNF, IL1B, IL10",1181,4,12971,10.9830651989839,0.999999999999955,0.0669034123884211,5.61331953178421]
["GAD_DISEASE","Aortic Aneurysm, Abdominal|Inflammation|Postoperative Complications",4,0.309597523219814,0.00280003722742694,"IL6, TNF, IL1B, IL10",1181,4,12971,10.9830651989839,0.999999999999955,0.0669034123884211,5.61331953178421]
["GAD_DISEASE","Infection|Kidney Failure, Acute",4,0.309597523219814,0.00280003722742694,"IL6, TNF, IL1B, IL10",1181,4,12971,10.9830651989839,0.999999999999955,0.0669034123884211,5.61331953178421]
["GAD_DISEASE","Chronic Periodontitis|Periodontitis",4,0.309597523219814,0.00280003722742694,"IL6, TNF, IL1B, IL1A",1181,4,12971,10.9830651989839,0.999999999999955,0.0669034123884211,5.61331953178421]
["GAD_DISEASE","Dementia|Inflammation",4,0.309597523219814,0.00280003722742694,"IL6, TNF, IL1B, IL1A",1181,4,12971,10.9830651989839,0.999999999999955,0.0669034123884211,5.61331953178421]
["GAD_DISEASE","Esophageal Neoplasms|Oesophageal neoplasm|Stomach Neoplasms",5,0.386996904024767,0.00353620226448439,"GSTM1, IL6, TNF, IL1B, IL10",1181,8,12971,6.86441574936494,1,0.0834075328662788,7.03858472337265]
["GAD_DISEASE","Cachexia|Esophageal Neoplasms|Stomach Neoplasms",4,0.309597523219814,0.00652587858657671,"IL6, TNF, IL1B, IL10",1181,5,12971,8.78645215918713,1,0.145374045255921,12.6191139188296]
["GAD_DISEASE","cytokine production",4,0.309597523219814,0.00652587858657671,"IL6, TNF, IL1B, IL10",1181,5,12971,8.78645215918713,1,0.145374045255921,12.6191139188296]
["GAD_DISEASE","Esophagitis|Gastritis, Atrophic|Gastroesophageal Reflux|Helicobacter Infections",3,0.23219814241486,0.0233063975432453,"TNF, IL1B, IL10",1181,3,12971,10.9830651989839,1,0.415192508197618,38.4836377101908]
["GAD_DISEASE","Glossitis, Benign Migratory",3,0.23219814241486,0.0233063975432453,"IL6, TNF, IL1B",1181,3,12971,10.9830651989839,1,0.415192508197618,38.4836377101908]
["GAD_DISEASE","Asphyxia Neonatorum|Brain Ischemia|Hypoxia-Ischemia, Brain",3,0.23219814241486,0.0233063975432453,"IL6, TNF, IL1B",1181,3,12971,10.9830651989839,1,0.415192508197618,38.4836377101908]
["GAD_DISEASE","Critical Illness|",3,0.23219814241486,0.0233063975432453,"IL6, TNF, IL1B",1181,3,12971,10.9830651989839,1,0.415192508197618,38.4836377101908]
["GAD_DISEASE","Burns|Multiple Organ Failure|Shock",3,0.23219814241486,0.0438127578581207,"IL6, TNF, IL1B",1181,4,12971,8.23729889923793,1,0.630065979941808,60.2693790825589]
["GAD_DISEASE","appendicitis",3,0.23219814241486,0.0686706773740773,"IL6, TNF, IL1B",1181,5,12971,6.58983911939034,1,0.788585717782312,76.9095009968113]
["GAD_DISEASE","Burns|Shock, Septic",3,0.23219814241486,0.0686706773740773,"IL6, TNF, IL1B",1181,5,12971,6.58983911939034,1,0.788585717782312,76.9095009968113]
[]
["Annotation Cluster 11","Enrichment Score: 2.286613579554859"]
["Category","Term","Count","%","PValue","Genes","List Total","Pop Hits","Pop Total","Fold Enrichment","Bonferroni","Benjamini","FDR"]
["GAD_DISEASE","Critical Illness|Multiple Organ Failure|Systemic inflam response synd|Systemic Inflammatory Response Syndrome",4,0.309597523219814,0.00280003722742694,"IL6, TNF, IL1RN, IL1B",1181,4,12971,10.9830651989839,0.999999999999955,0.0669034123884211,5.61331953178421]
["GAD_DISEASE","Diabetes mellitus type II|Diabetes Mellitus, Type 2|Diabetic Nephropathies|Diabetic Nephropathy|Inflammation",4,0.309597523219814,0.00280003722742694,"IL6, TNF, IL1RN, IL1B",1181,4,12971,10.9830651989839,0.999999999999955,0.0669034123884211,5.61331953178421]
["GAD_DISEASE","Dermatitis, Allergic Contact|Dermatitis, Atopic|Eczema allergic",4,0.309597523219814,0.00280003722742694,"IL6, TNF, IL1RN, IL1B",1181,4,12971,10.9830651989839,0.999999999999955,0.0669034123884211,5.61331953178421]
["GAD_DISEASE","Measles|Mumps|Rubella",5,0.386996904024767,0.0325127919786301,"IL6, TNF, IL2RA, IL1RN, IL1B",1181,14,12971,3.92252328535139,1,0.523438959124694,49.3886395189872]
[]
["Annotation Cluster 12","Enrichment Score: 2.1500021577491384"]
["Category","Term","Count","%","PValue","Genes","List Total","Pop Hits","Pop Total","Fold Enrichment","Bonferroni","Benjamini","FDR"]
["GAD_DISEASE","Glucose Transporter Type 2",6,0.464396284829721,{"v":0.000569698468124036,"d":"5.70E-04"},"GCK, ADCY5, SLC2A2, ADRA2A, MTNR1B, IGF1",1181,9,12971,7.32204346598927,0.998066693944139,0.0148727609445568,1.16722147138663]
["GAD_DISEASE","fasting glucose-related traits ",6,0.464396284829721,0.0151055953602158,"GCK, ADCY5, SLC2A2, ADRA2A, MTNR1B, IGF1",1181,17,12971,3.87637595258255,1,0.29942668818536,26.9185669867215]
["GAD_DISEASE","Glucose Tolerance Test",5,0.386996904024767,0.0412297430467745,"GCK, ADCY5, SLC2A2, ADRA2A, MTNR1B",1181,15,12971,3.66102173299463,1,0.608727053167397,57.998572737732]
[]
["Annotation Cluster 13","Enrichment Score: 2.064191056021286"]
["Category","Term","Count","%","PValue","Genes","List Total","Pop Hits","Pop Total","Fold Enrichment","Bonferroni","Benjamini","FDR"]
["GAD_DISEASE","Eclampsia|Pre-Eclampsia",5,0.386996904024767,{"v":0.000316142988028513,"d":"3.16E-04"},"IL6, MTHFR, TNF, TGFB1, IL10",1181,5,12971,10.9830651989839,0.96879122380206,0.00846168283503379,0.649336547548296]
["GAD_DISEASE","Hepatitis C|Recurrence",5,0.386996904024767,{"v":0.000879837172786953,"d":"8.80E-04"},"ACE, IL6, TNF, TGFB1, IL10",1181,6,12971,9.15255433248659,0.999935681365791,0.022506221462588,1.7971851943858]
["GAD_DISEASE","Hepatitis C|Pregnancy Complications, Infectious",5,0.386996904024767,0.00190496493893241,"TNF, HLA-DRB1, IFNG, TGFB1, IL10",1181,7,12971,7.84504657070279,0.999999999168559,0.0466134493640447,3.85238462728602]
["GAD_DISEASE","allograft dysfunction, renal",4,0.309597523219814,0.00280003722742694,"IL6, TNF, TGFB1, IL10",1181,4,12971,10.9830651989839,0.999999999999955,0.0669034123884211,5.61331953178421]
["GAD_DISEASE","Clonorchiasis|Fibrosis",4,0.309597523219814,0.00280003722742694,"TNF, IFNG, TGFB1, IL10",1181,4,12971,10.9830651989839,0.999999999999955,0.0669034123884211,5.61331953178421]
["GAD_DISEASE","Autoimmune Diseases|Pelvic Pain|Prostatitis|Syndrome",4,0.309597523219814,0.00280003722742694,"IL6, TNF, TGFB1, IL10",1181,4,12971,10.9830651989839,0.999999999999955,0.0669034123884211,5.61331953178421]
["GAD_DISEASE","Alveolitis, Extrinsic Allergic|Bird Fancier's Lung|Extrinsic allergic alveolitis",4,0.309597523219814,0.00280003722742694,"IL6, TNF, TGFB1, IL10",1181,4,12971,10.9830651989839,0.999999999999955,0.0669034123884211,5.61331953178421]
["GAD_DISEASE","cardiomyopathy; heart anomalies, congenital",4,0.309597523219814,0.00280003722742694,"TNF, IFNG, TGFB1, IL10",1181,4,12971,10.9830651989839,0.999999999999955,0.0669034123884211,5.61331953178421]
["GAD_DISEASE","Hepatitis B|Recurrence",4,0.309597523219814,0.00652587858657671,"TNF, CTLA4, TGFB1, IL10",1181,5,12971,8.78645215918713,1,0.145374045255921,12.6191139188296]
["GAD_DISEASE","Brucellosis|",4,0.309597523219814,0.00652587858657671,"IL6, TNF, TGFB1, IL10",1181,5,12971,8.78645215918713,1,0.145374045255921,12.6191139188296]
["GAD_DISEASE","Epstein-Barr Virus Infections|Lymphoproliferative Disorders",4,0.309597523219814,0.00652587858657671,"TNF, IFNG, TGFB1, IL10",1181,5,12971,8.78645215918713,1,0.145374045255921,12.6191139188296]
["GAD_DISEASE","Silicosis|Tuberculosis, Pulmonary",3,0.23219814241486,0.0233063975432453,"TNF, TGFB1, IL10",1181,3,12971,10.9830651989839,1,0.415192508197618,38.4836377101908]
["GAD_DISEASE","Cardiovascular Diseases|Hypertrophy, Left Ventricular|Left Ventricular Hypertrophy",3,0.23219814241486,0.0233063975432453,"TNF, TGFB1, IL10",1181,3,12971,10.9830651989839,1,0.415192508197618,38.4836377101908]
["GAD_DISEASE","Chronic renal failure|Diabetic Nephropathies|Diabetic Nephropathy|Glomerulonephritis|Kidney Failure, Chronic",3,0.23219814241486,0.0233063975432453,"TNF, TGFB1, IL10",1181,3,12971,10.9830651989839,1,0.415192508197618,38.4836377101908]
["GAD_DISEASE","Liver Failure",3,0.23219814241486,0.0233063975432453,"TNF, TGFB1, IL10",1181,3,12971,10.9830651989839,1,0.415192508197618,38.4836377101908]
["GAD_DISEASE","liver disease; hepatitis C, chronic",3,0.23219814241486,0.0233063975432453,"IFNG, TGFB1, IL10",1181,3,12971,10.9830651989839,1,0.415192508197618,38.4836377101908]
["GAD_DISEASE","Fatty Liver|Hepatitis C, Chronic|Insulin Resistance",3,0.23219814241486,0.0438127578581207,"IL6, TGFB1, IL10",1181,4,12971,8.23729889923793,1,0.630065979941808,60.2693790825589]
["GAD_DISEASE","Glomerulonephritis, IGA|Kidney Failure, Chronic",3,0.23219814241486,0.0438127578581207,"IL6, TNF, TGFB1",1181,4,12971,8.23729889923793,1,0.630065979941808,60.2693790825589]
["GAD_DISEASE","Pulmonary Disease, Chronic Obstructive|Pulmonary Emphysema",3,0.23219814241486,0.0969200560616097,"TNF, IFNG, TGFB1",1181,6,12971,5.49153259949195,1,0.88780434582701,87.7587799802275]
["GAD_DISEASE","Cadaver",3,0.23219814241486,0.160427733051525,"TNF, TGFB1, IL10",1181,8,12971,4.11864944961896,1,0.974781370114907,97.2750091930555]
[]
["Annotation Cluster 14","Enrichment Score: 1.9852356041270298"]
["Category","Term","Count","%","PValue","Genes","List Total","Pop Hits","Pop Total","Fold Enrichment","Bonferroni","Benjamini","FDR"]
["GAD_DISEASE","gastroenteritis",4,0.309597523219814,0.00280003722742694,"IL6, IL1RN, IL1B, IL10",1181,4,12971,10.9830651989839,0.999999999999955,0.0669034123884211,5.61331953178421]
["GAD_DISEASE","Inflammation|Neoplasms",4,0.309597523219814,0.00280003722742694,"TNF, IL1RN, IL1B, IL10",1181,4,12971,10.9830651989839,0.999999999999955,0.0669034123884211,5.61331953178421]
["GAD_DISEASE","asthma; candidiasis; high-altitude illness",5,0.386996904024767,0.00353620226448439,"IL4, TNF, IL1RN, IL1B, IL10",1181,8,12971,6.86441574936494,1,0.0834075328662788,7.03858472337265]
["GAD_DISEASE","infection, postoperative",4,0.309597523219814,0.00652587858657671,"TNF, IL1RN, IL1B, IL10",1181,5,12971,8.78645215918713,1,0.145374045255921,12.6191139188296]
["GAD_DISEASE","Cachexia|Stomach Neoplasms",3,0.23219814241486,0.0233063975432453,"IL1RN, IL1B, IL10",1181,3,12971,10.9830651989839,1,0.415192508197618,38.4836377101908]
["GAD_DISEASE","BILIARY CIRRHOSIS|Hepatitis, Autoimmune|Liver Cirrhosis, Biliary",3,0.23219814241486,0.0438127578581207,"IL1RN, IL1B, IL10",1181,4,12971,8.23729889923793,1,0.630065979941808,60.2693790825589]
["GAD_DISEASE","Helicobacter Infections|Precancerous Conditions|Stomach Neoplasms",3,0.23219814241486,0.0686706773740773,"IL1RN, IL1B, IL10",1181,5,12971,6.58983911939034,1,0.788585717782312,76.9095009968113]
[]
["Annotation Cluster 15","Enrichment Score: 1.945654723817253"]
["Category","Term","Count","%","PValue","Genes","List Total","Pop Hits","Pop Total","Fold Enrichment","Bonferroni","Benjamini","FDR"]
["GAD_DISEASE","HIV Infections|Neuritis|Somatosensory Disorders",5,0.386996904024767,{"v":0.000879837172786953,"d":"8.80E-04"},"TNF, HLA-DRB1, HLA-A, HLA-B, IL12B",1181,6,12971,9.15255433248659,0.999935681365791,0.022506221462588,1.7971851943858]
["GAD_DISEASE","Periodontal Attachment Loss|Periodontitis",4,0.309597523219814,0.00280003722742694,"TNF, HLA-A, HLA-B, IL1A",1181,4,12971,10.9830651989839,0.999999999999955,0.0669034123884211,5.61331953178421]
["GAD_DISEASE","Autoimmune Diseases|Retroperitoneal Fibrosis",4,0.309597523219814,0.00280003722742694,"TNF, HLA-DRB1, HLA-A, HLA-B",1181,4,12971,10.9830651989839,0.999999999999955,0.0669034123884211,5.61331953178421]
["GAD_DISEASE","AIDS-Related Opportunistic Infections|Cytomegalovirus Retinitis|Encephalomyelitis|HIV Infections|Hypersensitivity|Mycobacterium avium-intracellulare Infection|[X]Human immunodeficiency virus disease",4,0.309597523219814,0.00280003722742694,"IL6, TNF, HLA-A, HLA-B",1181,4,12971,10.9830651989839,0.999999999999955,0.0669034123884211,5.61331953178421]
["GAD_DISEASE","Anemia, Aplastic|Aplastic anemia|Genetic Diseases, Inborn|Graft vs Host Disease|Hematologic Neoplasms|Recurrence",4,0.309597523219814,0.00652587858657671,"TNF, HLA-DRB1, HLA-A, HLA-B",1181,5,12971,8.78645215918713,1,0.145374045255921,12.6191139188296]
["GAD_DISEASE","natural antibodies",5,0.386996904024767,0.00914624039590833,"TNF, HLA-DRB1, HLA-A, HLA-B, HLA-DQA1",1181,10,12971,5.49153259949195,1,0.195554882301746,17.2467985809626]
["GAD_DISEASE","Behcet Syndrome|Uveitis",3,0.23219814241486,0.0686706773740773,"TNF, HLA-A, HLA-B",1181,5,12971,6.58983911939034,1,0.788585717782312,76.9095009968113]
["GAD_DISEASE","Hemochromatosis|Iron Overload",3,0.23219814241486,0.0969200560616097,"TNF, HLA-A, HLA-B",1181,6,12971,5.49153259949195,1,0.88780434582701,87.7587799802275]
["GAD_DISEASE","Varicose Ulcer",3,0.23219814241486,0.40192699203356,"TNF, HLA-DRB1, HLA-B",1181,15,12971,2.19661303979678,1,0.999949247686815,99.9974854745183]
[]
["Annotation Cluster 16","Enrichment Score: 1.939295298140331"]
["Category","Term","Count","%","PValue","Genes","List Total","Pop Hits","Pop Total","Fold Enrichment","Bonferroni","Benjamini","FDR"]
["GAD_DISEASE","shyness",4,0.309597523219814,0.00280003722742694,"MAOA, SLC6A4, DRD4, COMT",1181,4,12971,10.9830651989839,0.999999999999955,0.0669034123884211,5.61331953178421]
["GAD_DISEASE","depressive disorder, major endocrine regulation",3,0.23219814241486,0.0233063975432453,"MAOA, SLC6A4, COMT",1181,3,12971,10.9830651989839,1,0.415192508197618,38.4836377101908]
["GAD_DISEASE","Depression, Postpartum|",3,0.23219814241486,0.0233063975432453,"MAOA, SLC6A4, COMT",1181,3,12971,10.9830651989839,1,0.415192508197618,38.4836377101908]
[]
["Annotation Cluster 17","Enrichment Score: 1.939295298140331"]
["Category","Term","Count","%","PValue","Genes","List Total","Pop Hits","Pop Total","Fold Enrichment","Bonferroni","Benjamini","FDR"]
["GAD_DISEASE","Fam hyperbetalipoproteinaemia|Hyperlipoproteinemia Type II",4,0.309597523219814,0.00280003722742694,"APOB, LDLR, APOE, PCSK9",1181,4,12971,10.9830651989839,0.999999999999955,0.0669034123884211,5.61331953178421]
["GAD_DISEASE","atherosclerosis, coronary cholesterol",3,0.23219814241486,0.0233063975432453,"APOB, LDLR, PCSK9",1181,3,12971,10.9830651989839,1,0.415192508197618,38.4836377101908]
["GAD_DISEASE","heart disease, ischemic hypercholesterolemia",3,0.23219814241486,0.0233063975432453,"APOB, LDLR, PCSK9",1181,3,12971,10.9830651989839,1,0.415192508197618,38.4836377101908]
[]
["Annotation Cluster 18","Enrichment Score: 1.8909992112650356"]
["Category","Term","Count","%","PValue","Genes","List Total","Pop Hits","Pop Total","Fold Enrichment","Bonferroni","Benjamini","FDR"]
["GAD_DISEASE","Fuchs heterochromic cyclitis",4,0.309597523219814,0.00280003722742694,"HLA-DQB1, TNF, HLA-DRB1, CTLA4",1181,4,12971,10.9830651989839,0.999999999999955,0.0669034123884211,5.61331953178421]
["GAD_DISEASE","beta cell autoimmunity",4,0.309597523219814,0.00280003722742694,"HLA-DQB1, HLA-DRB1, INS, CTLA4",1181,4,12971,10.9830651989839,0.999999999999955,0.0669034123884211,5.61331953178421]
["GAD_DISEASE","thyroiditis, Hashimoto's",3,0.23219814241486,0.0233063975432453,"HLA-DQB1, HLA-DRB1, CTLA4",1181,3,12971,10.9830651989839,1,0.415192508197618,38.4836377101908]
["GAD_DISEASE","diabetes, type 1 thyroid autoimmunity",3,0.23219814241486,0.0438127578581207,"HLA-DQB1, HLA-DRB1, CTLA4",1181,4,12971,8.23729889923793,1,0.630065979941808,60.2693790825589]
["GAD_DISEASE","diabetes, type 1; thyroid disease, autoimmune",3,0.23219814241486,0.0438127578581207,"HLA-DQB1, HLA-DRB1, CTLA4",1181,4,12971,8.23729889923793,1,0.630065979941808,60.2693790825589]
[]
["Annotation Cluster 19","Enrichment Score: 1.8896804020497626"]
["Category","Term","Count","%","PValue","Genes","List Total","Pop Hits","Pop Total","Fold Enrichment","Bonferroni","Benjamini","FDR"]
["GAD_DISEASE","vulvar cancer",5,0.386996904024767,{"v":0.000316142988028513,"d":"3.16E-04"},"IL6, IL1RN, IL1B, NOS3, IL1A",1181,5,12971,10.9830651989839,0.96879122380206,0.00846168283503379,0.649336547548296]
["GAD_DISEASE","Periodontal Diseases",5,0.386996904024767,{"v":0.000879837172786953,"d":"8.80E-04"},"IL6, IL1RN, IL1B, IL10, IL1A",1181,6,12971,9.15255433248659,0.999935681365791,0.022506221462588,1.7971851943858]
["GAD_DISEASE","Pneumoconiosis|Silicosis",4,0.309597523219814,0.00280003722742694,"TNF, IL1RN, IL1B, IL1A",1181,4,12971,10.9830651989839,0.999999999999955,0.0669034123884211,5.61331953178421]
["GAD_DISEASE","coal workers pneumoconiosis",4,0.309597523219814,0.00280003722742694,"TNF, IL1RN, IL1B, IL1A",1181,4,12971,10.9830651989839,0.999999999999955,0.0669034123884211,5.61331953178421]
["GAD_DISEASE","Bone Diseases, Metabolic|Osteoporosis, Postmenopausal",4,0.309597523219814,0.00280003722742694,"IL6, IL1RN, IL1B, IL1A",1181,4,12971,10.9830651989839,0.999999999999955,0.0669034123884211,5.61331953178421]
["GAD_DISEASE","Dental Plaque|Gingivitis",4,0.309597523219814,0.00280003722742694,"IL6, IL1RN, IL1B, IL1A",1181,4,12971,10.9830651989839,0.999999999999955,0.0669034123884211,5.61331953178421]
["GAD_DISEASE","Erythema",4,0.309597523219814,0.00280003722742694,"TNF, IL1RN, IL1B, IL1A",1181,4,12971,10.9830651989839,0.999999999999955,0.0669034123884211,5.61331953178421]
["GAD_DISEASE","Nasal Polyps|Rhinitis|Sinusitis",4,0.309597523219814,0.00652587858657671,"TNF, MET, IL1B, IL1A",1181,5,12971,8.78645215918713,1,0.145374045255921,12.6191139188296]
["GAD_DISEASE","Arthritis, Juvenile Rheumatoid|Arthritis, Rheumatoid|Chronic Childhood Arthritis|Periodontitis|Rheumatoid Arthritis",4,0.309597523219814,0.00652587858657671,"TNF, IL1RN, IL1B, IL1A",1181,5,12971,8.78645215918713,1,0.145374045255921,12.6191139188296]
["GAD_DISEASE","Autoimmune Diseases|Thyroid Diseases",4,0.309597523219814,0.00652587858657671,"IL2RA, IL1RN, IL1B, IL1A",1181,5,12971,8.78645215918713,1,0.145374045255921,12.6191139188296]
["GAD_DISEASE","Berylliosis|Respiratory Hypersensitivity",4,0.309597523219814,0.0121719200005317,"IL1RN, IL1B, IL1A, IL2",1181,6,12971,7.32204346598927,1,0.250825117332743,22.3001907789742]
["GAD_DISEASE","Osteomyelitis|Unspecified osteomyelitis NOS",3,0.23219814241486,0.0233063975432453,"TNF, IL1B, IL1A",1181,3,12971,10.9830651989839,1,0.415192508197618,38.4836377101908]
["GAD_DISEASE","Death|Sudden Infant Death",3,0.23219814241486,0.0233063975432453,"IL1RN, IL1B, IL1A",1181,3,12971,10.9830651989839,1,0.415192508197618,38.4836377101908]
["GAD_DISEASE","Bone Diseases|Degenerative arthropathy |Osteoarthritis",3,0.23219814241486,0.0233063975432453,"IL1RN, IL1B, IL1A",1181,3,12971,10.9830651989839,1,0.415192508197618,38.4836377101908]
["GAD_DISEASE","Aortic Aneurysm, Abdominal|Arteriosclerosis",3,0.23219814241486,0.0233063975432453,"IL1RN, IL1B, IL1A",1181,3,12971,10.9830651989839,1,0.415192508197618,38.4836377101908]
["GAD_DISEASE","Ache, Low Back|Intervertebral Disk Displacement|Low Back Pain",3,0.23219814241486,0.0233063975432453,"IL1RN, IL1B, IL1A",1181,3,12971,10.9830651989839,1,0.415192508197618,38.4836377101908]
["GAD_DISEASE","Aspergillosis|Hematologic Neoplasms|Lung Diseases, Fungal",3,0.23219814241486,0.0233063975432453,"IL1RN, IL1B, IL1A",1181,3,12971,10.9830651989839,1,0.415192508197618,38.4836377101908]
["GAD_DISEASE","Dermatitis, Irritant|",3,0.23219814241486,0.0233063975432453,"IL1RN, IL1B, IL1A",1181,3,12971,10.9830651989839,1,0.415192508197618,38.4836377101908]
["GAD_DISEASE","Early Onset Periodontitis",3,0.23219814241486,0.0233063975432453,"IL1RN, IL1B, IL1A",1181,3,12971,10.9830651989839,1,0.415192508197618,38.4836377101908]
["GAD_DISEASE","pesticide exposure |  vaccination response",3,0.23219814241486,0.0233063975432453,"IL1RN, IL1B, IL1A",1181,3,12971,10.9830651989839,1,0.415192508197618,38.4836377101908]
["GAD_DISEASE","dysthymia",3,0.23219814241486,0.0233063975432453,"IL1RN, IL1B, IL1A",1181,3,12971,10.9830651989839,1,0.415192508197618,38.4836377101908]
["GAD_DISEASE","Alveolar Bone Loss",3,0.23219814241486,0.0233063975432453,"TNF, IL1B, IL1A",1181,3,12971,10.9830651989839,1,0.415192508197618,38.4836377101908]
["GAD_DISEASE","Alveolar Bone Loss|Coronary Disease|Diabetes Complications|Periodontitis|Tooth Loss",3,0.23219814241486,0.0233063975432453,"IL1RN, IL1B, IL1A",1181,3,12971,10.9830651989839,1,0.415192508197618,38.4836377101908]
["GAD_DISEASE","Inflammation|Migraine Disorders",3,0.23219814241486,0.0233063975432453,"IL1RN, IL1B, IL1A",1181,3,12971,10.9830651989839,1,0.415192508197618,38.4836377101908]
["GAD_DISEASE","Lung Diseases, Obstructive|Scleroderma, Systemic|Systemic Scleroderma",3,0.23219814241486,0.0438127578581207,"IL1RN, IL1B, IL1A",1181,4,12971,8.23729889923793,1,0.630065979941808,60.2693790825589]
["GAD_DISEASE","fat mass",3,0.23219814241486,0.0438127578581207,"IL1RN, IL1B, IL1A",1181,4,12971,8.23729889923793,1,0.630065979941808,60.2693790825589]
["GAD_DISEASE","Occupational Diseases|Osteoarthritis",3,0.23219814241486,0.0686706773740773,"IL1RN, IL1B, IL1A",1181,5,12971,6.58983911939034,1,0.788585717782312,76.9095009968113]
["GAD_DISEASE","Arthritis, Rheumatoid|Periodontitis|Rheumatoid Arthritis",3,0.23219814241486,0.0969200560616097,"IL1RN, IL1B, IL1A",1181,6,12971,5.49153259949195,1,0.88780434582701,87.7587799802275]
["GAD_DISEASE","Aggressive Periodontitis|",3,0.23219814241486,0.127739223966434,"IL1RN, IL1B, IL1A",1181,7,12971,4.70702794242167,1,0.945205773685763,94.0140408904238]
[]
["Annotation Cluster 20","Enrichment Score: 1.8864944643175674"]
["Category","Term","Count","%","PValue","Genes","List Total","Pop Hits","Pop Total","Fold Enrichment","Bonferroni","Benjamini","FDR"]
["GAD_DISEASE","AIDS Dementia Complex|AIDS Related Dementia Complex",4,0.309597523219814,0.00280003722742694,"TNF, APOE, IL1RN, IL1B",1181,4,12971,10.9830651989839,0.999999999999955,0.0669034123884211,5.61331953178421]
["GAD_DISEASE","Carcinoma|Helicobacter Infections|Stomach Neoplasms",4,0.309597523219814,0.00280003722742694,"TNF, IL1RN, IL1B, CDH1",1181,4,12971,10.9830651989839,0.999999999999955,0.0669034123884211,5.61331953178421]
["GAD_DISEASE","Precancerous Conditions|Stomach Neoplasms",4,0.309597523219814,0.00280003722742694,"TNF, CYP1A1, IL1RN, IL1B",1181,4,12971,10.9830651989839,0.999999999999955,0.0669034123884211,5.61331953178421]
["GAD_DISEASE","preterm labour",4,0.309597523219814,0.00652587858657671,"IL4, TNF, IL1RN, IL1B",1181,5,12971,8.78645215918713,1,0.145374045255921,12.6191139188296]
["GAD_DISEASE","Helicobacter Infections|Purpura, Thrombocytopenic, Idiopathic",4,0.309597523219814,0.0121719200005317,"IGHG1, TNF, IL1RN, IL1B",1181,6,12971,7.32204346598927,1,0.250825117332743,22.3001907789742]
["GAD_DISEASE","stomach cancer; gastritis",3,0.23219814241486,0.0233063975432453,"TNF, IL1RN, IL1B",1181,3,12971,10.9830651989839,1,0.415192508197618,38.4836377101908]
["GAD_DISEASE","Apoplexy|Brain Ischemia|Encephalitis|Stroke",3,0.23219814241486,0.0233063975432453,"TNF, IL1RN, IL1B",1181,3,12971,10.9830651989839,1,0.415192508197618,38.4836377101908]
["GAD_DISEASE","Duodenal Ulcer|Gastrointestinal Diseases|Helicobacter Infections|Stomach Neoplasms|Stomach Ulcer|stomach; ulcer",3,0.23219814241486,0.0233063975432453,"TNF, IL1RN, IL1B",1181,3,12971,10.9830651989839,1,0.415192508197618,38.4836377101908]
["GAD_DISEASE","chronic atrophic gastritis and gastric carcinoma",3,0.23219814241486,0.0233063975432453,"TNF, IL1RN, IL1B",1181,3,12971,10.9830651989839,1,0.415192508197618,38.4836377101908]
["GAD_DISEASE","Bacterial Vaginosis|Vaginosis, Bacterial",3,0.23219814241486,0.0233063975432453,"TNF, IL1RN, IL1B",1181,3,12971,10.9830651989839,1,0.415192508197618,38.4836377101908]
["GAD_DISEASE","Duodenal Ulcer|Gastritis|Helicobacter Infections|Stomach Neoplasms",3,0.23219814241486,0.0438127578581207,"TNF, IL1RN, IL1B",1181,4,12971,8.23729889923793,1,0.630065979941808,60.2693790825589]
["GAD_DISEASE","Gastroesophageal Reflux|Helicobacter Infections",3,0.23219814241486,0.0438127578581207,"TNF, IL1RN, IL1B",1181,4,12971,8.23729889923793,1,0.630065979941808,60.2693790825589]
[]
["Annotation Cluster 21","Enrichment Score: 1.86260268609166"]
["Category","Term","Count","%","PValue","Genes","List Total","Pop Hits","Pop Total","Fold Enrichment","Bonferroni","Benjamini","FDR"]
["GAD_DISEASE","Cardiovascular Diseases|Myocardial Ischemia",4,0.309597523219814,0.00280003722742694,"ADRB3, ADRB2, ADRB1, ADRA1A",1181,4,12971,10.9830651989839,0.999999999999955,0.0669034123884211,5.61331953178421]
["GAD_DISEASE","heart rate, resting",3,0.23219814241486,0.0233063975432453,"ADRB3, ADRB2, ADRB1",1181,3,12971,10.9830651989839,1,0.415192508197618,38.4836377101908]
["GAD_DISEASE","body mass; obesity, localized",3,0.23219814241486,0.0233063975432453,"ADRB3, ADRB2, ADRB1",1181,3,12971,10.9830651989839,1,0.415192508197618,38.4836377101908]
["GAD_DISEASE","cardiomyopathy; heart failure",3,0.23219814241486,0.0233063975432453,"ADRB3, ADRB2, ADRB1",1181,3,12971,10.9830651989839,1,0.415192508197618,38.4836377101908]
[]
["Annotation Cluster 22","Enrichment Score: 1.86260268609166"]
["Category","Term","Count","%","PValue","Genes","List Total","Pop Hits","Pop Total","Fold Enrichment","Bonferroni","Benjamini","FDR"]
["GAD_DISEASE","Cystadenocarcinoma, Mucinous|Cystadenocarcinoma, Serous|pancreatic neoplasm|Pancreatic Neoplasms",4,0.309597523219814,0.00280003722742694,"EGFR, KRAS, BRAF, PIK3CA",1181,4,12971,10.9830651989839,0.999999999999955,0.0669034123884211,5.61331953178421]
["GAD_DISEASE","Adenocarcinoma|Lung Neoplasms|Lymphatic Metastasis",3,0.23219814241486,0.0233063975432453,"EGFR, KRAS, BRAF",1181,3,12971,10.9830651989839,1,0.415192508197618,38.4836377101908]
["GAD_DISEASE","Adenocarcinoma, Papillary|Lung Neoplasms",3,0.23219814241486,0.0233063975432453,"EGFR, KRAS, BRAF",1181,3,12971,10.9830651989839,1,0.415192508197618,38.4836377101908]
["GAD_DISEASE","Adenocarcinoma|Carcinoma, Non-Small-Cell Lung",3,0.23219814241486,0.0233063975432453,"EGFR, KRAS, BRAF",1181,3,12971,10.9830651989839,1,0.415192508197618,38.4836377101908]
[]
["Annotation Cluster 23","Enrichment Score: 1.8479201510451373"]
["Category","Term","Count","%","PValue","Genes","List Total","Pop Hits","Pop Total","Fold Enrichment","Bonferroni","Benjamini","FDR"]
["GAD_DISEASE","negative affective facial stimuli ",4,0.309597523219814,0.00280003722742694,"HTR1A, SLC6A4, TPH2, HTR2A",1181,4,12971,10.9830651989839,0.999999999999955,0.0669034123884211,5.61331953178421]
["GAD_DISEASE","depression, interferon-induced",3,0.23219814241486,0.0233063975432453,"HTR1A, SLC6A4, TPH2",1181,3,12971,10.9830651989839,1,0.415192508197618,38.4836377101908]
["GAD_DISEASE","risk-taking behavior in a gambling task ",3,0.23219814241486,0.0438127578581207,"HTR1A, SLC6A4, TPH2",1181,4,12971,8.23729889923793,1,0.630065979941808,60.2693790825589]
[]
["Annotation Cluster 24","Enrichment Score: 1.8441118955024043"]
["Category","Term","Count","%","PValue","Genes","List Total","Pop Hits","Pop Total","Fold Enrichment","Bonferroni","Benjamini","FDR"]
["GAD_DISEASE","2-thiothiazolidine-4-carboxylic acid levels",4,0.309597523219814,0.0121719200005317,"GSTM1, GCLC, GCLM, GSTP1",1181,6,12971,7.32204346598927,1,0.250825117332743,22.3001907789742]
["GAD_DISEASE","methylmercury retention",4,0.309597523219814,0.0121719200005317,"GSTM1, GCLC, GCLM, GSTP1",1181,6,12971,7.32204346598927,1,0.250825117332743,22.3001907789742]
["GAD_DISEASE","immunologic markers among vulcanization workers ",4,0.309597523219814,0.0121719200005317,"GSTM1, GCLC, GCLM, GSTP1",1181,6,12971,7.32204346598927,1,0.250825117332743,22.3001907789742]
["GAD_DISEASE","body burden of methylmercury",3,0.23219814241486,0.0233063975432453,"GCLC, GCLM, GSTP1",1181,3,12971,10.9830651989839,1,0.415192508197618,38.4836377101908]
[]
["Annotation Cluster 25","Enrichment Score: 1.832974336196387"]
["Category","Term","Count","%","PValue","Genes","List Total","Pop Hits","Pop Total","Fold Enrichment","Bonferroni","Benjamini","FDR"]
["GAD_DISEASE","Disease Models, Animal|Fever|Seizures, Febrile",4,0.309597523219814,0.00280003722742694,"IL6, TNF, CXCL8, IL10",1181,4,12971,10.9830651989839,0.999999999999955,0.0669034123884211,5.61331953178421]
["GAD_DISEASE","kidney disease; vascular disease",4,0.309597523219814,0.00280003722742694,"IL6, TNF, IL10, IL2",1181,4,12971,10.9830651989839,0.999999999999955,0.0669034123884211,5.61331953178421]
["GAD_DISEASE","acute rejection",4,0.309597523219814,0.00280003722742694,"IL6, TNF, VEGFA, IL10",1181,4,12971,10.9830651989839,0.999999999999955,0.0669034123884211,5.61331953178421]
["GAD_DISEASE","Bronchitis, Chronic|Bronchopneumonia|Chronic bronchitis |Communicable Diseases",3,0.23219814241486,0.0233063975432453,"IL6, TNF, IL10",1181,3,12971,10.9830651989839,1,0.415192508197618,38.4836377101908]
["GAD_DISEASE","Acute Lung Injury|Inflammation",3,0.23219814241486,0.0233063975432453,"IL6, TNF, IL10",1181,3,12971,10.9830651989839,1,0.415192508197618,38.4836377101908]
["GAD_DISEASE","Burns|Sepsis|Systemic infection",3,0.23219814241486,0.0969200560616097,"IL6, TNF, IL10",1181,6,12971,5.49153259949195,1,0.88780434582701,87.7587799802275]
["GAD_DISEASE","Aspergillosis|Lung Diseases, Fungal",3,0.23219814241486,0.127739223966434,"IL6, TNF, IL10",1181,7,12971,4.70702794242167,1,0.945205773685763,94.0140408904238]
[]
["Annotation Cluster 26","Enrichment Score: 1.8165871188624572"]
["Category","Term","Count","%","PValue","Genes","List Total","Pop Hits","Pop Total","Fold Enrichment","Bonferroni","Benjamini","FDR"]
["GAD_DISEASE","Cystadenocarcinoma, Mucinous|Cystadenocarcinoma, Serous|pancreatic neoplasm|Pancreatic Neoplasms",4,0.309597523219814,0.00280003722742694,"EGFR, KRAS, BRAF, PIK3CA",1181,4,12971,10.9830651989839,0.999999999999955,0.0669034123884211,5.61331953178421]
["GAD_DISEASE","Carcinoma|Colonic Polyps|Colorectal Neoplasms",3,0.23219814241486,0.0233063975432453,"KRAS, BRAF, PIK3CA",1181,3,12971,10.9830651989839,1,0.415192508197618,38.4836377101908]
["GAD_DISEASE","colorectal cancer; stomach cancer",3,0.23219814241486,0.0233063975432453,"KRAS, BRAF, PIK3CA",1181,3,12971,10.9830651989839,1,0.415192508197618,38.4836377101908]
["GAD_DISEASE","Carcinoma, Squamous Cell|Gingival Neoplasms|Mandibular Neoplasms|Maxillary Neoplasms|Mouth Neoplasms|Tongue Neoplasms",3,0.23219814241486,0.0233063975432453,"KRAS, BRAF, PIK3CA",1181,3,12971,10.9830651989839,1,0.415192508197618,38.4836377101908]
["GAD_DISEASE","Adenocarcinoma|Colonic Neoplasms|Microsatellite Instability",3,0.23219814241486,0.0233063975432453,"KRAS, BRAF, PIK3CA",1181,3,12971,10.9830651989839,1,0.415192508197618,38.4836377101908]
[]
["Annotation Cluster 27","Enrichment Score: 1.7888285014145735"]
["Category","Term","Count","%","PValue","Genes","List Total","Pop Hits","Pop Total","Fold Enrichment","Bonferroni","Benjamini","FDR"]
["GAD_DISEASE","nelfinavir pharmacokinetics",4,0.309597523219814,0.00280003722742694,"ABCC1, ABCB1, ABCC2, ABCG2",1181,4,12971,10.9830651989839,0.999999999999955,0.0669034123884211,5.61331953178421]
["GAD_DISEASE","bilirubin indinavir oral clearance lamivudine-triphosphate concentration zidovudine-triphosphate concentration",4,0.309597523219814,0.00652587858657671,"ABCB1, ABCC2, UGT1A1, ABCG2",1181,5,12971,8.78645215918713,1,0.145374045255921,12.6191139188296]
["GAD_DISEASE","9-aminocamptothecin pharmacokinetics 9-nitrocamptothecin pharmacokinetics",3,0.23219814241486,0.0233063975432453,"ABCB1, ABCC2, ABCG2",1181,3,12971,10.9830651989839,1,0.415192508197618,38.4836377101908]
["GAD_DISEASE","telmisartan",3,0.23219814241486,0.0233063975432453,"ABCB1, ABCC2, ABCG2",1181,3,12971,10.9830651989839,1,0.415192508197618,38.4836377101908]
["GAD_DISEASE","irinotecan pharmacokinetics irinotecan toxicity lung cancer",3,0.23219814241486,0.0233063975432453,"ABCB1, ABCC2, ABCG2",1181,3,12971,10.9830651989839,1,0.415192508197618,38.4836377101908]
["GAD_DISEASE","Epilepsies, Partial",4,0.309597523219814,0.0296736967160852,"NTRK2, ABCB1, ABCC2, ABCG2",1181,8,12971,5.49153259949195,1,0.493902162431577,46.2390556747162]
["GAD_DISEASE","metabolite of mycophenolic acid",3,0.23219814241486,0.0438127578581207,"ABCB1, ABCC2, ABCG2",1181,4,12971,8.23729889923793,1,0.630065979941808,60.2693790825589]
[]
["Annotation Cluster 28","Enrichment Score: 1.7748941901928357"]
["Category","Term","Count","%","PValue","Genes","List Total","Pop Hits","Pop Total","Fold Enrichment","Bonferroni","Benjamini","FDR"]
["GAD_DISEASE","Altitude Sickness|Chronic Disease",5,0.386996904024767,{"v":0.000316142988028513,"d":"3.16E-04"},"AGTR1, ACE, APOB, AGT, GNB3",1181,5,12971,10.9830651989839,0.96879122380206,0.00846168283503379,0.649336547548296]
["GAD_DISEASE","cerebral white matter lesions",4,0.309597523219814,0.00280003722742694,"AGTR1, ACE, AGT, NOS3",1181,4,12971,10.9830651989839,0.999999999999955,0.0669034123884211,5.61331953178421]
["GAD_DISEASE","arterial disease",4,0.309597523219814,0.00280003722742694,"AGTR1, ACE, AGT, NOS3",1181,4,12971,10.9830651989839,0.999999999999955,0.0669034123884211,5.61331953178421]
["GAD_DISEASE","peritoneal transport",4,0.309597523219814,0.00280003722742694,"AGTR1, ACE, AGT, NOS3",1181,4,12971,10.9830651989839,0.999999999999955,0.0669034123884211,5.61331953178421]
["GAD_DISEASE","Hypertension|Metabolic Syndrome X",4,0.309597523219814,0.00280003722742694,"AGTR1, ACE, AGT, GNB3",1181,4,12971,10.9830651989839,0.999999999999955,0.0669034123884211,5.61331953178421]
["GAD_DISEASE","Hypertension|Kidney Failure, Chronic",4,0.309597523219814,0.00280003722742694,"AGTR1, ACE, AGT, ITGB3",1181,4,12971,10.9830651989839,0.999999999999955,0.0669034123884211,5.61331953178421]
["GAD_DISEASE","Chronic renal failure|Glomerulonephritis, IGA|IGA Glomerulonephritides|Kidney Failure, Chronic",4,0.309597523219814,0.00280003722742694,"AGTR1, ACE, CCR5, AGT",1181,4,12971,10.9830651989839,0.999999999999955,0.0669034123884211,5.61331953178421]
["GAD_DISEASE","esophageal varices",4,0.309597523219814,0.00280003722742694,"AGTR1, ACE, AGT, NOS3",1181,4,12971,10.9830651989839,0.999999999999955,0.0669034123884211,5.61331953178421]
["GAD_DISEASE","atherosclerosis, generalized blood pressure, arterial cardiovascular disease",4,0.309597523219814,0.00280003722742694,"AGTR1, ACE, AGT, NOS3",1181,4,12971,10.9830651989839,0.999999999999955,0.0669034123884211,5.61331953178421]
["GAD_DISEASE","sudden cardiac arrest risk",5,0.386996904024767,0.00353620226448439,"KNG1, AGTR1, ACE, REN, AGT",1181,8,12971,6.86441574936494,1,0.0834075328662788,7.03858472337265]
["GAD_DISEASE","blood pressure, arterial; atherosclerosis",4,0.309597523219814,0.00652587858657671,"AGTR1, ACE, AGT, MMP3",1181,5,12971,8.78645215918713,1,0.145374045255921,12.6191139188296]
["GAD_DISEASE","Diabetes Mellitus|Diabetic Angiopathies|Hypertension",4,0.309597523219814,0.00652587858657671,"AGTR1, ACE, REN, AGT",1181,5,12971,8.78645215918713,1,0.145374045255921,12.6191139188296]
["GAD_DISEASE","posttransplantation erythrocytosis",4,0.309597523219814,0.00652587858657671,"AGTR1, ACE, AGT, NOS3",1181,5,12971,8.78645215918713,1,0.145374045255921,12.6191139188296]
["GAD_DISEASE","cysclosporine toxicity",4,0.309597523219814,0.00652587858657671,"AGTR1, ACE, AGT, NOS3",1181,5,12971,8.78645215918713,1,0.145374045255921,12.6191139188296]
["GAD_DISEASE","aortic stiffness",4,0.309597523219814,0.0121719200005317,"AGTR1, ACE, AGT, COL1A1",1181,6,12971,7.32204346598927,1,0.250825117332743,22.3001907789742]
["GAD_DISEASE","myocardial infarct stroke",4,0.309597523219814,0.0121719200005317,"AGTR1, ACE, AGT, GNB3",1181,6,12971,7.32204346598927,1,0.250825117332743,22.3001907789742]
["GAD_DISEASE","Body Weight|Hypertension|Obesity",3,0.23219814241486,0.0233063975432453,"AGTR1, ACE, AGT",1181,3,12971,10.9830651989839,1,0.415192508197618,38.4836377101908]
["GAD_DISEASE","nephropathy, diabetic; blood pressure, arterial; proteinuria",3,0.23219814241486,0.0233063975432453,"AGTR1, ACE, AGT",1181,3,12971,10.9830651989839,1,0.415192508197618,38.4836377101908]
["GAD_DISEASE","Cerebral Arterial Diseases|Constriction, Pathologic|Diabetes mellitus type II|Diabetes Mellitus, Type 2",3,0.23219814241486,0.0233063975432453,"AGTR1, ACE, AGT",1181,3,12971,10.9830651989839,1,0.415192508197618,38.4836377101908]
["GAD_DISEASE","Dyslipidemias|Metabolic Syndrome X|Obesity|Renal hypertension",3,0.23219814241486,0.0233063975432453,"AGTR1, ACE, AGT",1181,3,12971,10.9830651989839,1,0.415192508197618,38.4836377101908]
["GAD_DISEASE","Chronic renal failure|Kidney Failure, Chronic|Uremia|Vesico-Ureteral Reflux|Vesicoureteral reflux",3,0.23219814241486,0.0233063975432453,"AGTR1, ACE, AGT",1181,3,12971,10.9830651989839,1,0.415192508197618,38.4836377101908]
["GAD_DISEASE","type 2 diabetic nephropathy",3,0.23219814241486,0.0233063975432453,"AGTR1, ACE, AGT",1181,3,12971,10.9830651989839,1,0.415192508197618,38.4836377101908]
["GAD_DISEASE","Chronic renal failure|Kidney Failure, Chronic|Nephritis, Interstitial",3,0.23219814241486,0.0233063975432453,"AGTR1, ACE, AGT",1181,3,12971,10.9830651989839,1,0.415192508197618,38.4836377101908]
["GAD_DISEASE","Chronic renal failure|Hypertension|Kidney Failure, Chronic|Lupus Erythematosus, Systemic|Lupus Nephritis|Nephritis SLE|Systemic lupus erythematosus",3,0.23219814241486,0.0233063975432453,"AGTR1, ACE, AGT",1181,3,12971,10.9830651989839,1,0.415192508197618,38.4836377101908]
["GAD_DISEASE","Fibromuscular Dysplasia|Hypertension|Renal Artery Obstruction",3,0.23219814241486,0.0233063975432453,"AGTR1, ACE, AGT",1181,3,12971,10.9830651989839,1,0.415192508197618,38.4836377101908]
["GAD_DISEASE","Chronic renal failure|Death, Sudden, Cardiac|Kidney Failure, Chronic|Long QT Syndrome|Sudden Cardiac Death",3,0.23219814241486,0.0233063975432453,"AGTR1, ACE, AGT",1181,3,12971,10.9830651989839,1,0.415192508197618,38.4836377101908]
["GAD_DISEASE","Fibrosis|Glomerulonephritis, IGA|Hepatitis C, Chronic|IGA Glomerulonephritides",3,0.23219814241486,0.0233063975432453,"AGTR1, ACE, AGT",1181,3,12971,10.9830651989839,1,0.415192508197618,38.4836377101908]
["GAD_DISEASE","Diabetes mellitus type II|Diabetes Mellitus, Type 2|Hypertension",3,0.23219814241486,0.0233063975432453,"AGTR1, ACE, AGT",1181,3,12971,10.9830651989839,1,0.415192508197618,38.4836377101908]
["GAD_DISEASE","Hypertrophy, Left Ventricular|Left Ventricular Hypertrophy|Ventricular Remodeling",3,0.23219814241486,0.0233063975432453,"AGTR1, ACE, AGT",1181,3,12971,10.9830651989839,1,0.415192508197618,38.4836377101908]
["GAD_DISEASE","Edema|Nephrotic Syndrome",3,0.23219814241486,0.0233063975432453,"AGTR1, ACE, AGT",1181,3,12971,10.9830651989839,1,0.415192508197618,38.4836377101908]
["GAD_DISEASE","Diabetes mellitus type II|Diabetes Mellitus, Type 2|Diabetic Nephropathies|Diabetic Nephropathy|Diabetic Neuropathies|Disease Susceptibility",3,0.23219814241486,0.0233063975432453,"AGTR1, ACE, AGT",1181,3,12971,10.9830651989839,1,0.415192508197618,38.4836377101908]
["GAD_DISEASE","Kidney Function Post-Kidney Transplant",3,0.23219814241486,0.0233063975432453,"AGTR1, ACE, AGT",1181,3,12971,10.9830651989839,1,0.415192508197618,38.4836377101908]
["GAD_DISEASE","coronary artery thrombosis",3,0.23219814241486,0.0233063975432453,"AGTR1, ACE, AGT",1181,3,12971,10.9830651989839,1,0.415192508197618,38.4836377101908]
["GAD_DISEASE","Gastrointestinal Diseases|Gastrointestinal Hemorrhage|Peptic Ulcer|Peptic Ulcer Hemorrhage",3,0.23219814241486,0.0233063975432453,"AGTR1, ACE, AGT",1181,3,12971,10.9830651989839,1,0.415192508197618,38.4836377101908]
["GAD_DISEASE","coronary atherosclerosis.",3,0.23219814241486,0.0233063975432453,"AGTR1, ACE, AGT",1181,3,12971,10.9830651989839,1,0.415192508197618,38.4836377101908]
["GAD_DISEASE","Coronary Disease|Coronary heart disease|Hyperlipidemias|Hyperlipoproteinemia Type I",3,0.23219814241486,0.0233063975432453,"AGTR1, ACE, AGT",1181,3,12971,10.9830651989839,1,0.415192508197618,38.4836377101908]
["GAD_DISEASE","Chronic Glomerulonephritis",3,0.23219814241486,0.0233063975432453,"AGTR1, ACE, AGT",1181,3,12971,10.9830651989839,1,0.415192508197618,38.4836377101908]
["GAD_DISEASE","Coronary Stenosis|Recurrence",3,0.23219814241486,0.0233063975432453,"AGTR1, ACE, AGT",1181,3,12971,10.9830651989839,1,0.415192508197618,38.4836377101908]
["GAD_DISEASE","Cardiovascular Diseases|Carotid Artery Diseases|Cerebrovascular Disorders|Hypertension",3,0.23219814241486,0.0233063975432453,"AGTR1, ACE, AGT",1181,3,12971,10.9830651989839,1,0.415192508197618,38.4836377101908]
["GAD_DISEASE","Henoch-Schoenlein Purpura|Kidney Diseases|Nephrotic Syndrome|Proteinuria|Purpura, Schoenlein-Henoch",3,0.23219814241486,0.0233063975432453,"AGTR1, ACE, AGT",1181,3,12971,10.9830651989839,1,0.415192508197618,38.4836377101908]
["GAD_DISEASE","Coronary Restenosis|Diabetes mellitus|Myocardial ischemia|Recurrence",3,0.23219814241486,0.0233063975432453,"AGTR1, ACE, AGT",1181,3,12971,10.9830651989839,1,0.415192508197618,38.4836377101908]
["GAD_DISEASE","Heart Failure, Diastolic",3,0.23219814241486,0.0233063975432453,"AGTR1, ACE, AGT",1181,3,12971,10.9830651989839,1,0.415192508197618,38.4836377101908]
["GAD_DISEASE","Glomerulonephritis, IGA|IGA Glomerulonephritides|Proteinuria",3,0.23219814241486,0.0233063975432453,"AGTR1, ACE, AGT",1181,3,12971,10.9830651989839,1,0.415192508197618,38.4836377101908]
["GAD_DISEASE","Albuminuria|Cardiovascular Diseases|Diabetes Mellitus, Type 2|Hypertension|Kidney Diseases",3,0.23219814241486,0.0233063975432453,"AGTR1, ACE, AGT",1181,3,12971,10.9830651989839,1,0.415192508197618,38.4836377101908]
["GAD_DISEASE","hypertension; left ventricular hypertrophy",4,0.309597523219814,0.0296736967160852,"AGTR1, ACE, ADRB1, AGT",1181,8,12971,5.49153259949195,1,0.493902162431577,46.2390556747162]
["OMIM_DISEASE","267430~Renal tubular dysgenesis",4,0.309597523219814,0.0366771081203355,"AGTR1, ACE, REN, AGT",1056,4,4740,4.48863636363636,1,0.999999957501184,47.0198226140914]
["GAD_DISEASE","Hypertension, Renal|Hypertrophy, Left Ventricular|Retinal Diseases",3,0.23219814241486,0.0438127578581207,"AGTR1, ACE, AGT",1181,4,12971,8.23729889923793,1,0.630065979941808,60.2693790825589]
["GAD_DISEASE","renal allograft function",3,0.23219814241486,0.0438127578581207,"AGTR1, ACE, AGT",1181,4,12971,8.23729889923793,1,0.630065979941808,60.2693790825589]
["GAD_DISEASE","Hypertension|Kidney Diseases",3,0.23219814241486,0.0438127578581207,"AGTR1, ACE, AGT",1181,4,12971,8.23729889923793,1,0.630065979941808,60.2693790825589]
["GAD_DISEASE","Kidney Failure, Chronic|Vesico-Ureteral Reflux",3,0.23219814241486,0.0438127578581207,"AGTR1, ACE, AGT",1181,4,12971,8.23729889923793,1,0.630065979941808,60.2693790825589]
["GAD_DISEASE","Diabetes Mellitus, Type 1|Hypoglycemia",3,0.23219814241486,0.0438127578581207,"AGTR1, ACE, AGT",1181,4,12971,8.23729889923793,1,0.630065979941808,60.2693790825589]
["GAD_DISEASE","Polycystic Kidney Diseases",3,0.23219814241486,0.0438127578581207,"AGTR1, ACE, AGT",1181,4,12971,8.23729889923793,1,0.630065979941808,60.2693790825589]
["GAD_DISEASE","Diabetes Mellitus|Hypertension",3,0.23219814241486,0.0438127578581207,"AGTR1, ACE, AGT",1181,4,12971,8.23729889923793,1,0.630065979941808,60.2693790825589]
["GAD_DISEASE","hypertension; blood pressure, arterial",3,0.23219814241486,0.0686706773740773,"ACE, AGT, NOS3",1181,5,12971,6.58983911939034,1,0.788585717782312,76.9095009968113]
["GAD_DISEASE","Cardiomyopathy, Hypertrophic, Familial|Hypertrophy, Left Ventricular",3,0.23219814241486,0.0686706773740773,"AGTR1, ACE, AGT",1181,5,12971,6.58983911939034,1,0.788585717782312,76.9095009968113]
["GAD_DISEASE","Cardiomyopathies|Heart Defects, Congenital",3,0.23219814241486,0.0686706773740773,"AGTR1, ACE, AGT",1181,5,12971,6.58983911939034,1,0.788585717782312,76.9095009968113]
["GAD_DISEASE","Connective Tissue Diseases|Hypertension, Pulmonary",3,0.23219814241486,0.0686706773740773,"AGTR1, ACE, AGT",1181,5,12971,6.58983911939034,1,0.788585717782312,76.9095009968113]
["GAD_DISEASE","Heart Failure|Hypertension",3,0.23219814241486,0.0686706773740773,"AGTR1, ACE, REN",1181,5,12971,6.58983911939034,1,0.788585717782312,76.9095009968113]
[]
["Annotation Cluster 29","Enrichment Score: 1.7718802095727113"]
["Category","Term","Count","%","PValue","Genes","List Total","Pop Hits","Pop Total","Fold Enrichment","Bonferroni","Benjamini","FDR"]
["GAD_DISEASE","thrombotic diseases",4,0.309597523219814,0.00652587858657671,"ACE, MTHFR, F2, F7",1181,5,12971,8.78645215918713,1,0.145374045255921,12.6191139188296]
["GAD_DISEASE","Brain Ischemia|Intracranial Arterial Diseases|Stroke",4,0.309597523219814,0.00652587858657671,"ACE, MTHFR, F2, NOS3",1181,5,12971,8.78645215918713,1,0.145374045255921,12.6191139188296]
["GAD_DISEASE","Apoplexy|Brain Ischemia|Diabetes Complications|Hypertension|Stroke",4,0.309597523219814,0.00652587858657671,"ACE, MTHFR, APOE, F2",1181,5,12971,8.78645215918713,1,0.145374045255921,12.6191139188296]
["GAD_DISEASE","Pregnancy Complications, Hematologic|Premature Birth|Thrombophilia",4,0.309597523219814,0.00652587858657671,"ACE, MTHFR, TNF, F2",1181,5,12971,8.78645215918713,1,0.145374045255921,12.6191139188296]
["GAD_DISEASE","Complication, Cardiovascular Pregnancy|Pregnancy Complications, Cardiovascular|Venous Thrombosis",3,0.23219814241486,0.0438127578581207,"ACE, MTHFR, F2",1181,4,12971,8.23729889923793,1,0.630065979941808,60.2693790825589]
["GAD_DISEASE","preterm labor",3,0.23219814241486,0.0438127578581207,"ACE, MTHFR, F2",1181,4,12971,8.23729889923793,1,0.630065979941808,60.2693790825589]
["GAD_DISEASE","Pulmonary Embolism|Pulmonary Embolisms",3,0.23219814241486,0.0438127578581207,"ACE, MTHFR, F2",1181,4,12971,8.23729889923793,1,0.630065979941808,60.2693790825589]
["GAD_DISEASE","Brain Ischemia|Stroke|Thrombophilia",3,0.23219814241486,0.0438127578581207,"ACE, MTHFR, F2",1181,4,12971,8.23729889923793,1,0.630065979941808,60.2693790825589]
[]
["Annotation Cluster 30","Enrichment Score: 1.7571946566382357"]
["Category","Term","Count","%","PValue","Genes","List Total","Pop Hits","Pop Total","Fold Enrichment","Bonferroni","Benjamini","FDR"]
["GAD_DISEASE","hyperhomocystinemia",5,0.386996904024767,{"v":0.000879837172786953,"d":"8.80E-04"},"MTHFR, MTR, NOS3, CBS, MTRR",1181,6,12971,9.15255433248659,0.999935681365791,0.022506221462588,1.7971851943858]
["GAD_DISEASE","Down Syndrome|",5,0.386996904024767,{"v":0.000879837172786953,"d":"8.80E-04"},"CD55, MTHFR, MTR, CBS, MTRR",1181,6,12971,9.15255433248659,0.999935681365791,0.022506221462588,1.7971851943858]
["GAD_DISEASE","plasma homocysteine",4,0.309597523219814,0.00280003722742694,"MTHFR, MTR, CBS, MTRR",1181,4,12971,10.9830651989839,0.999999999999955,0.0669034123884211,5.61331953178421]
["GAD_DISEASE","Adrenoleukodystrophy|Demyelinating Diseases|Metabolic Diseases",4,0.309597523219814,0.00280003722742694,"MTHFR, DHFR, MTR, MTRR",1181,4,12971,10.9830651989839,0.999999999999955,0.0669034123884211,5.61331953178421]
["GAD_DISEASE","Coronary Artery Disease|Hyperhomocysteinemia",4,0.309597523219814,0.00652587858657671,"MTHFR, MTR, F2, MTRR",1181,5,12971,8.78645215918713,1,0.145374045255921,12.6191139188296]
["GAD_DISEASE","Congenital Heart Defects|Down Syndrome|Heart Defects, Congenital|Heart Septal Defects",4,0.309597523219814,0.00652587858657671,"MTHFR, MTR, CBS, MTRR",1181,5,12971,8.78645215918713,1,0.145374045255921,12.6191139188296]
["GAD_DISEASE","homocysteine metabolism, cognition, and white matter lesions",4,0.309597523219814,0.00652587858657671,"MTHFR, MTR, CBS, MTRR",1181,5,12971,8.78645215918713,1,0.145374045255921,12.6191139188296]
["GAD_DISEASE","orofacial clefts",5,0.386996904024767,0.018607322398107,"MTHFR, MTR, PCYT1A, CBS, MTRR",1181,12,12971,4.57627716624329,1,0.353004022321468,32.0894750153729]
["GAD_DISEASE","Fetal anticonvulsant syndrome",3,0.23219814241486,0.0233063975432453,"MTHFR, MTR, MTRR",1181,3,12971,10.9830651989839,1,0.415192508197618,38.4836377101908]
["GAD_DISEASE","Diseases in Twins|Myocardial ischemia",3,0.23219814241486,0.0233063975432453,"MTHFR, MTR, MTRR",1181,3,12971,10.9830651989839,1,0.415192508197618,38.4836377101908]
["GAD_DISEASE","Hyperhomocysteinemia|Pre-Eclampsia",3,0.23219814241486,0.0233063975432453,"MTHFR, MTR, MTRR",1181,3,12971,10.9830651989839,1,0.415192508197618,38.4836377101908]
["GAD_DISEASE","reduced sperm counts",3,0.23219814241486,0.0233063975432453,"MTHFR, CBS, MTRR",1181,3,12971,10.9830651989839,1,0.415192508197618,38.4836377101908]
["GAD_DISEASE","serum folate and serum total homocysteine",3,0.23219814241486,0.0233063975432453,"MTHFR, CBS, MTRR",1181,3,12971,10.9830651989839,1,0.415192508197618,38.4836377101908]
["GAD_DISEASE","Chronic progressive chorea|Huntington Disease",5,0.386996904024767,0.0249800765605915,"MTHFR, APOE, MTR, CBS, MTRR",1181,13,12971,4.22425584576304,1,0.436899706448474,40.6194240453251]
["GAD_DISEASE","Congenital Abnormalities",4,0.309597523219814,0.0296736967160852,"MTHFR, MTR, CBS, MTRR",1181,8,12971,5.49153259949195,1,0.493902162431577,46.2390556747162]
["GAD_DISEASE","Folic Acid Deficiency",4,0.309597523219814,0.0296736967160852,"MTHFR, DHFR, MTR, MTRR",1181,8,12971,5.49153259949195,1,0.493902162431577,46.2390556747162]
["GAD_DISEASE","chromosomal damage",4,0.309597523219814,0.0415558424226315,"MTHFR, MTR, MTRR, ERCC2",1181,9,12971,4.88136231065951,1,0.610936466450014,58.2919211685126]
["GAD_DISEASE","Hyperhomocysteinemia|Phenylketonurias|Vitamin B Deficiency",3,0.23219814241486,0.0438127578581207,"MTHFR, MTR, MTRR",1181,4,12971,8.23729889923793,1,0.630065979941808,60.2693790825589]
["GAD_DISEASE","embryo selection",3,0.23219814241486,0.0438127578581207,"MTHFR, MTR, MTRR",1181,4,12971,8.23729889923793,1,0.630065979941808,60.2693790825589]
["GAD_DISEASE","Congenital Abnormalities|",3,0.23219814241486,0.0438127578581207,"MTHFR, MTR, MTRR",1181,4,12971,8.23729889923793,1,0.630065979941808,60.2693790825589]
["GAD_DISEASE","preterm delivery small-for-gestational age",3,0.23219814241486,0.0438127578581207,"MTHFR, MTR, MTRR",1181,4,12971,8.23729889923793,1,0.630065979941808,60.2693790825589]
["GAD_DISEASE","atherosclerosis, coronary; homocysteine",3,0.23219814241486,0.0438127578581207,"MTHFR, MTR, MTRR",1181,4,12971,8.23729889923793,1,0.630065979941808,60.2693790825589]
["GAD_DISEASE","neural tube defects   ",4,0.309597523219814,0.0554456718634368,"MTHFR, DHFR, MTR, MTRR",1181,10,12971,4.39322607959356,1,0.715196693770559,69.1255310393718]
["GAD_DISEASE","Anemia, Iron-Deficiency|Avitaminosis",3,0.23219814241486,0.0686706773740773,"MTHFR, MTR, MTRR",1181,5,12971,6.58983911939034,1,0.788585717782312,76.9095009968113]
["GAD_DISEASE","frequency of micronucleated lymphocytes",3,0.23219814241486,0.0969200560616097,"MTHFR, MTR, MTRR",1181,6,12971,5.49153259949195,1,0.88780434582701,87.7587799802275]
[]
["Annotation Cluster 31","Enrichment Score: 1.7565450039499433"]
["Category","Term","Count","%","PValue","Genes","List Total","Pop Hits","Pop Total","Fold Enrichment","Bonferroni","Benjamini","FDR"]
["GAD_DISEASE","Drug Hypersensitivity|HIV Infections",4,0.309597523219814,0.00280003722742694,"HLA-DQB1, HLA-DRB1, HLA-C, HLA-B",1181,4,12971,10.9830651989839,0.999999999999955,0.0669034123884211,5.61331953178421]
["GAD_DISEASE","Hepatitis C, Chronic|Substance-Related Disorders|Viremia",3,0.23219814241486,0.0438127578581207,"HLA-DQB1, HLA-DRB1, HLA-C",1181,4,12971,8.23729889923793,1,0.630065979941808,60.2693790825589]
["GAD_DISEASE","Diabetes Mellitus|Hepatitis C|Liver Diseases",3,0.23219814241486,0.0438127578581207,"HLA-DQB1, HLA-DRB1, HLA-C",1181,4,12971,8.23729889923793,1,0.630065979941808,60.2693790825589]
[]
["Annotation Cluster 32","Enrichment Score: 1.7452786407709207"]
["Category","Term","Count","%","PValue","Genes","List Total","Pop Hits","Pop Total","Fold Enrichment","Bonferroni","Benjamini","FDR"]
["GAD_DISEASE","negative affective facial stimuli ",4,0.309597523219814,0.00280003722742694,"HTR1A, SLC6A4, TPH2, HTR2A",1181,4,12971,10.9830651989839,0.999999999999955,0.0669034123884211,5.61331953178421]
["GAD_DISEASE","frontal brain electrical asymmetry",3,0.23219814241486,0.0233063975432453,"HTR1A, SLC6A4, HTR2A",1181,3,12971,10.9830651989839,1,0.415192508197618,38.4836377101908]
["GAD_DISEASE","Panic disorder ",3,0.23219814241486,0.0233063975432453,"HTR1A, SLC6A4, HTR2A",1181,3,12971,10.9830651989839,1,0.415192508197618,38.4836377101908]
["GAD_DISEASE","suicide | mood disorders",3,0.23219814241486,0.0686706773740773,"HTR1A, SLC6A4, HTR2A",1181,5,12971,6.58983911939034,1,0.788585717782312,76.9095009968113]
[]
["Annotation Cluster 33","Enrichment Score: 1.7243302497658737"]
["Category","Term","Count","%","PValue","Genes","List Total","Pop Hits","Pop Total","Fold Enrichment","Bonferroni","Benjamini","FDR"]
["GAD_DISEASE","Carcinoma, Squamous Cell|Mouth Neoplasms|Oropharyngeal Neoplasms",5,0.386996904024767,0.00353620226448439,"GSTM1, CYP1A1, NAT2, MPO, GSTP1",1181,8,12971,6.86441574936494,1,0.0834075328662788,7.03858472337265]
["GAD_DISEASE","Carcinoma, Squamous Cell|Laryngeal neoplasm|Laryngeal Neoplasms|Squamous cell carcinoma",5,0.386996904024767,0.00590940530146925,"GSTM1, CYP1A1, NAT2, CYP2D6, GSTP1",1181,9,12971,6.10170288832439,1,0.133647341411972,11.4951582898578]
["GAD_DISEASE","tobacco consumption",4,0.309597523219814,0.00652587858657671,"GSTM1, CYP1A1, NAT2, GSTP1",1181,5,12971,8.78645215918713,1,0.145374045255921,12.6191139188296]
["GAD_DISEASE","metabolism of toluene di-isocyanate",5,0.386996904024767,0.00914624039590833,"GSTM1, CYP1A1, NAT2, MPO, GSTP1",1181,10,12971,5.49153259949195,1,0.195554882301746,17.2467985809626]
["GAD_DISEASE","Cleft Lip|Cleft Palate|Congenital Abnormalities",4,0.309597523219814,0.0121719200005317,"GSTM1, CYP1A1, NAT2, GSTP1",1181,6,12971,7.32204346598927,1,0.250825117332743,22.3001907789742]
["GAD_DISEASE","Head and Neck Neoplasms|Neoplasms, Multiple Primary",4,0.309597523219814,0.0415558424226315,"GSTM1, CYP1A1, NAT2, ERCC2",1181,9,12971,4.88136231065951,1,0.610936466450014,58.2919211685126]
["GAD_DISEASE","Birth Weight|Chromosome Aberrations|Chromosome abnormality|DNA Damage|Tobacco Use Disorder",3,0.23219814241486,0.0438127578581207,"GSTM1, CYP1A1, NAT2",1181,4,12971,8.23729889923793,1,0.630065979941808,60.2693790825589]
["GAD_DISEASE","cancer susceptibility",3,0.23219814241486,0.0438127578581207,"GSTM1, CYP1A1, NAT2",1181,4,12971,8.23729889923793,1,0.630065979941808,60.2693790825589]
["GAD_DISEASE","1-hydroxypyrene, urinary; 2-naphtol",3,0.23219814241486,0.0686706773740773,"GSTM1, CYP1A1, NAT2",1181,5,12971,6.58983911939034,1,0.788585717782312,76.9095009968113]
["GAD_DISEASE","malignant mesothelioma",3,0.23219814241486,0.0686706773740773,"GSTM1, CYP1A1, NAT2",1181,5,12971,6.58983911939034,1,0.788585717782312,76.9095009968113]
[]
["Annotation Cluster 34","Enrichment Score: 1.721082529046611"]
["Category","Term","Count","%","PValue","Genes","List Total","Pop Hits","Pop Total","Fold Enrichment","Bonferroni","Benjamini","FDR"]
["GAD_DISEASE","Epidermal Necrolysis, Toxic|Stevens-Johnson Syndrome|Toxic Epidermal Necrolysis",4,0.309597523219814,0.00280003722742694,"HLA-DRB1, HLA-A, HLA-C, HLA-B",1181,4,12971,10.9830651989839,0.999999999999955,0.0669034123884211,5.61331953178421]
["GAD_DISEASE","Cyclophosphamide",4,0.309597523219814,0.00280003722742694,"HLA-DRB1, HLA-A, HLA-C, HLA-B",1181,4,12971,10.9830651989839,0.999999999999955,0.0669034123884211,5.61331953178421]
["GAD_DISEASE","Autoimmune Diseases|Cholangitis, Sclerosing",4,0.309597523219814,0.00280003722742694,"HLA-DRB1, HLA-A, HLA-C, HLA-B",1181,4,12971,10.9830651989839,0.999999999999955,0.0669034123884211,5.61331953178421]
["GAD_DISEASE","Hypersensitivity|Skin Diseases",4,0.309597523219814,0.00280003722742694,"HLA-DRB1, HLA-A, HLA-C, HLA-B",1181,4,12971,10.9830651989839,0.999999999999955,0.0669034123884211,5.61331953178421]
["GAD_DISEASE","Drug Toxicity|Epidermal Necrolysis, Toxic|Stevens-Johnson Syndrome|Toxic Epidermal Necrolysis",4,0.309597523219814,0.00280003722742694,"HLA-DRB1, HLA-A, HLA-C, HLA-B",1181,4,12971,10.9830651989839,0.999999999999955,0.0669034123884211,5.61331953178421]
["GAD_DISEASE","Penile Induration|Peyronie Disease",4,0.309597523219814,0.00280003722742694,"HLA-A, HLA-C, HLA-B, TGFB1",1181,4,12971,10.9830651989839,0.999999999999955,0.0669034123884211,5.61331953178421]
["GAD_DISEASE","HTLV-I Infections|Paraparesis, Tropical Spastic|Tropical Spastic Paraparesis",4,0.309597523219814,0.00652587858657671,"HLA-DRB1, HLA-A, HLA-C, HLA-B",1181,5,12971,8.78645215918713,1,0.145374045255921,12.6191139188296]
["GAD_DISEASE","Dengue|Dengue Fever",4,0.309597523219814,0.00652587858657671,"HLA-DRB1, HLA-A, HLA-C, HLA-B",1181,5,12971,8.78645215918713,1,0.145374045255921,12.6191139188296]
["GAD_DISEASE","hepatitis C; hepatitis B",3,0.23219814241486,0.0233063975432453,"HLA-A, HLA-C, HLA-B",1181,3,12971,10.9830651989839,1,0.415192508197618,38.4836377101908]
["GAD_DISEASE","HTLV-I Infections|Spinal Cord Diseases",3,0.23219814241486,0.0233063975432453,"HLA-A, HLA-C, HLA-B",1181,3,12971,10.9830651989839,1,0.415192508197618,38.4836377101908]
["GAD_DISEASE","Epstein-Barr Virus Infections|Infectious mononucleosis",3,0.23219814241486,0.0233063975432453,"HLA-A, HLA-C, HLA-B",1181,3,12971,10.9830651989839,1,0.415192508197618,38.4836377101908]
["GAD_DISEASE","Conjunctivitis|Epidermal Necrolysis, Toxic|Stevens-Johnson Syndrome|Toxic Epidermal Necrolysis",3,0.23219814241486,0.0233063975432453,"HLA-A, HLA-C, HLA-B",1181,3,12971,10.9830651989839,1,0.415192508197618,38.4836377101908]
["GAD_DISEASE","HIV Infections|Viremia",3,0.23219814241486,0.0233063975432453,"HLA-A, HLA-C, HLA-B",1181,3,12971,10.9830651989839,1,0.415192508197618,38.4836377101908]
["GAD_DISEASE","Alcoholism|Diabetes mellitus type II|Diabetes Mellitus, Type 2|pancreatic neoplasm|Pancreatic Neoplasms",3,0.23219814241486,0.0233063975432453,"HLA-A, HLA-C, HLA-B",1181,3,12971,10.9830651989839,1,0.415192508197618,38.4836377101908]
["GAD_DISEASE","carbamazepine",3,0.23219814241486,0.0438127578581207,"HLA-A, HLA-C, HLA-B",1181,4,12971,8.23729889923793,1,0.630065979941808,60.2693790825589]
["GAD_DISEASE","Graft vs Host Disease|Leukemia|Leukemia, Myeloid|Myeloid Leukemia|Neoplasm Recurrence, Local",4,0.309597523219814,0.196937406078181,"HLA-DRB1, HLA-A, HLA-C, HLA-B",1181,17,12971,2.58425063505503,1,0.989207999414521,98.9096969491623]
["GAD_DISEASE","Leukemia, Myelogenous, Chronic, BCR-ABL Positive|Leukemia, Myeloid, Acute|Precursor Cell Lymphoblastic Leukemia-Lymphoma",3,0.23219814241486,0.40192699203356,"HLA-A, HLA-C, HLA-B",1181,15,12971,2.19661303979678,1,0.999949247686815,99.9974854745183]
["GAD_DISEASE","Axial Spondyloarthropathy",3,0.23219814241486,0.40192699203356,"HLA-A, HLA-C, HLA-B",1181,15,12971,2.19661303979678,1,0.999949247686815,99.9974854745183]
["GAD_DISEASE","HIV-1 control",3,0.23219814241486,0.434607368668992,"HLA-A, HLA-C, HLA-B",1181,16,12971,2.05932472480948,1,0.999981763510571,99.9992099436867]
[]
["Annotation Cluster 35","Enrichment Score: 1.7042001846233694"]
["Category","Term","Count","%","PValue","Genes","List Total","Pop Hits","Pop Total","Fold Enrichment","Bonferroni","Benjamini","FDR"]
["GAD_DISEASE","Birth Weight|Fetal Growth Retardation",4,0.309597523219814,0.00652587858657671,"GSTM1, CYP1A1, CYP2D6, GSTP1",1181,5,12971,8.78645215918713,1,0.145374045255921,12.6191139188296]
["GAD_DISEASE","manganism, susceptibility to occupational chronic",4,0.309597523219814,0.0121719200005317,"GSTM1, CYP1A1, CYP2D6, NQO1",1181,6,12971,7.32204346598927,1,0.250825117332743,22.3001907789742]
["GAD_DISEASE","acute lymphocytic leukemia|Leukemia, Myeloid, Acute|Precursor Cell Lymphoblastic Leukemia-Lymphoma",3,0.23219814241486,0.0438127578581207,"GSTM1, CYP1A1, CYP2D6",1181,4,12971,8.23729889923793,1,0.630065979941808,60.2693790825589]
["GAD_DISEASE","Alcohol-Related Disorders|Carcinoma, Squamous Cell|Head and Neck Neoplasms|Squamous cell carcinoma|Tobacco Use Disorder",3,0.23219814241486,0.0438127578581207,"GSTM1, CYP1A1, CYP2D6",1181,4,12971,8.23729889923793,1,0.630065979941808,60.2693790825589]
[]
["Annotation Cluster 36","Enrichment Score: 1.7042001846233694"]
["Category","Term","Count","%","PValue","Genes","List Total","Pop Hits","Pop Total","Fold Enrichment","Bonferroni","Benjamini","FDR"]
["GAD_DISEASE","phenanthrene metabolite ratios, urinary",4,0.309597523219814,0.00652587858657671,"GSTM1, CYP1B1, CYP1A1, GSTP1",1181,5,12971,8.78645215918713,1,0.145374045255921,12.6191139188296]
["GAD_DISEASE","mental development",4,0.309597523219814,0.0121719200005317,"GSTM1, CYP1B1, CYP1A1, CYP1A2",1181,6,12971,7.32204346598927,1,0.250825117332743,22.3001907789742]
["GAD_DISEASE","prenatal environment exposure",3,0.23219814241486,0.0438127578581207,"GSTM1, CYP1B1, CYP1A1",1181,4,12971,8.23729889923793,1,0.630065979941808,60.2693790825589]
["GAD_DISEASE","DNA Damage|Neoplasms",3,0.23219814241486,0.0438127578581207,"GSTM1, CYP1B1, CYP1A1",1181,4,12971,8.23729889923793,1,0.630065979941808,60.2693790825589]
[]
["Annotation Cluster 37","Enrichment Score: 1.674212484256286"]
["Category","Term","Count","%","PValue","Genes","List Total","Pop Hits","Pop Total","Fold Enrichment","Bonferroni","Benjamini","FDR"]
["GAD_DISEASE","Fuchs heterochromic cyclitis",4,0.309597523219814,0.00280003722742694,"HLA-DQB1, TNF, HLA-DRB1, CTLA4",1181,4,12971,10.9830651989839,0.999999999999955,0.0669034123884211,5.61331953178421]
["GAD_DISEASE","diabetes, type 1; measles",4,0.309597523219814,0.00652587858657671,"HLA-DQB1, TNF, HLA-DRB1, TAP1",1181,5,12971,8.78645215918713,1,0.145374045255921,12.6191139188296]
["GAD_DISEASE","scleroderma",4,0.309597523219814,0.0198721362964792,"HLA-DQB1, TNF, HLA-DRB1, COL3A1",1181,7,12971,6.27603725656223,1,0.370216045027357,33.870112521485]
["GAD_DISEASE","Multiple Sclerosis, Chronic Progressive",3,0.23219814241486,0.0233063975432453,"HLA-DQB1, TNF, HLA-DRB1",1181,3,12971,10.9830651989839,1,0.415192508197618,38.4836377101908]
["GAD_DISEASE","cutaneous neonatal lupus",3,0.23219814241486,0.0233063975432453,"HLA-DQB1, TNF, HLA-DRB1",1181,3,12971,10.9830651989839,1,0.415192508197618,38.4836377101908]
["GAD_DISEASE","leptospirosis",3,0.23219814241486,0.0233063975432453,"HLA-DQB1, TNF, HLA-DRB1",1181,3,12971,10.9830651989839,1,0.415192508197618,38.4836377101908]
["GAD_DISEASE","pancreatitis, autoimmune",3,0.23219814241486,0.0438127578581207,"HLA-DQB1, TNF, HLA-DRB1",1181,4,12971,8.23729889923793,1,0.630065979941808,60.2693790825589]
["GAD_DISEASE","Polyendocrinopathies, Autoimmune",3,0.23219814241486,0.0438127578581207,"HLA-DQB1, TNF, HLA-DRB1",1181,4,12971,8.23729889923793,1,0.630065979941808,60.2693790825589]
["GAD_DISEASE","mediterranean visceral leishmaniasis",3,0.23219814241486,0.0969200560616097,"HLA-DQB1, TNF, HLA-DRB1",1181,6,12971,5.49153259949195,1,0.88780434582701,87.7587799802275]
[]
["Annotation Cluster 38","Enrichment Score: 1.6558700470859198"]
["Category","Term","Count","%","PValue","Genes","List Total","Pop Hits","Pop Total","Fold Enrichment","Bonferroni","Benjamini","FDR"]
["GAD_DISEASE","diabetes, latent autoimmune",5,0.386996904024767,{"v":0.000316142988028513,"d":"3.16E-04"},"HLA-DQB1, HLA-DRB1, CTLA4, HLA-B, HLA-DQA1",1181,5,12971,10.9830651989839,0.96879122380206,0.00846168283503379,0.649336547548296]
["GAD_DISEASE","Dermatitis|Drug Hypersensitivity",4,0.309597523219814,0.00280003722742694,"HLA-DQB1, HLA-DRB1, HLA-B, HLA-DQA1",1181,4,12971,10.9830651989839,0.999999999999955,0.0669034123884211,5.61331953178421]
["GAD_DISEASE","jaundice",4,0.309597523219814,0.00652587858657671,"HLA-DQB1, HLA-DRB1, UGT1A1, HLA-DQA1",1181,5,12971,8.78645215918713,1,0.145374045255921,12.6191139188296]
["GAD_DISEASE","scleroderma; jaundice",4,0.309597523219814,0.00652587858657671,"HLA-DQB1, HLA-DRB1, HLA-A, HLA-DQA1",1181,5,12971,8.78645215918713,1,0.145374045255921,12.6191139188296]
["GAD_DISEASE","Myositis",4,0.309597523219814,0.0121719200005317,"HLA-DQB1, HLA-DRB1, HLA-B, HLA-DQA1",1181,6,12971,7.32204346598927,1,0.250825117332743,22.3001907789742]
["GAD_DISEASE","atherothrombosis",4,0.309597523219814,0.0198721362964792,"HLA-DQB1, TAF1, HLA-DRB1, HLA-DQA1",1181,7,12971,6.27603725656223,1,0.370216045027357,33.870112521485]
["GAD_DISEASE","psychological distress",3,0.23219814241486,0.0233063975432453,"HLA-DQB1, HLA-DRB1, HLA-DQA1",1181,3,12971,10.9830651989839,1,0.415192508197618,38.4836377101908]
["GAD_DISEASE","Diabetes Mellitus, Type 1|Disease Progression",3,0.23219814241486,0.0233063975432453,"HLA-DQB1, HLA-DRB1, HLA-DQA1",1181,3,12971,10.9830651989839,1,0.415192508197618,38.4836377101908]
["GAD_DISEASE","lung cancer; Lambert-Eaton myasthenic syndrome",3,0.23219814241486,0.0233063975432453,"HLA-DQB1, HLA-B, HLA-DQA1",1181,3,12971,10.9830651989839,1,0.415192508197618,38.4836377101908]
["GAD_DISEASE","multiple sclerosis; diabetes, type 1",3,0.23219814241486,0.0233063975432453,"HLA-DQB1, HLA-DRB1, HLA-DQA1",1181,3,12971,10.9830651989839,1,0.415192508197618,38.4836377101908]
["GAD_DISEASE","hypersomnolence",3,0.23219814241486,0.0233063975432453,"HLA-DQB1, HLA-DRB1, HLA-DQA1",1181,3,12971,10.9830651989839,1,0.415192508197618,38.4836377101908]
["GAD_DISEASE","hepatitis B vaccination",3,0.23219814241486,0.0233063975432453,"HLA-DQB1, HLA-DRB1, HLA-DQA1",1181,3,12971,10.9830651989839,1,0.415192508197618,38.4836377101908]
["GAD_DISEASE","Neoplasms, Germ Cell and Embryonal|Seminoma",3,0.23219814241486,0.0233063975432453,"HLA-DQB1, HLA-DRB1, HLA-DQA1",1181,3,12971,10.9830651989839,1,0.415192508197618,38.4836377101908]
["GAD_DISEASE","pemphigoid, bullous",3,0.23219814241486,0.0233063975432453,"HLA-DQB1, HLA-DRB1, HLA-DQA1",1181,3,12971,10.9830651989839,1,0.415192508197618,38.4836377101908]
["GAD_DISEASE","posttreatment Th2 immune response to S. mansoni Ags",3,0.23219814241486,0.0233063975432453,"HLA-DQB1, HLA-DRB1, HLA-DQA1",1181,3,12971,10.9830651989839,1,0.415192508197618,38.4836377101908]
["GAD_DISEASE","Leprosy, Lepromatous|Leprosy, Tuberculoid",3,0.23219814241486,0.0233063975432453,"HLA-DQB1, HLA-DRB1, HLA-DQA1",1181,3,12971,10.9830651989839,1,0.415192508197618,38.4836377101908]
["GAD_DISEASE","measles antibody level",3,0.23219814241486,0.0233063975432453,"HLA-DQB1, HLA-DRB1, HLA-DQA1",1181,3,12971,10.9830651989839,1,0.415192508197618,38.4836377101908]
["GAD_DISEASE","Calcinosis|Dermatomyositis",3,0.23219814241486,0.0233063975432453,"HLA-DQB1, HLA-DRB1, HLA-DQA1",1181,3,12971,10.9830651989839,1,0.415192508197618,38.4836377101908]
["GAD_DISEASE","Sarcoidosis, Pulmonary|Tuberculosis, Pulmonary",3,0.23219814241486,0.0233063975432453,"HLA-DQB1, HLA-DRB1, HLA-DQA1",1181,3,12971,10.9830651989839,1,0.415192508197618,38.4836377101908]
["GAD_DISEASE","diabetes, type 1; blood group incompatibility",3,0.23219814241486,0.0233063975432453,"HLA-DQB1, HLA-DRB1, HLA-DQA1",1181,3,12971,10.9830651989839,1,0.415192508197618,38.4836377101908]
["GAD_DISEASE","diabetes, type 1; autoimmune diabetes; diabetes, autoimmune",3,0.23219814241486,0.0233063975432453,"HLA-DQB1, HLA-DRB1, HLA-DQA1",1181,3,12971,10.9830651989839,1,0.415192508197618,38.4836377101908]
["GAD_DISEASE","Dermatomyositis|Myositis",3,0.23219814241486,0.0233063975432453,"HLA-DQB1, HLA-DRB1, HLA-DQA1",1181,3,12971,10.9830651989839,1,0.415192508197618,38.4836377101908]
["GAD_DISEASE","bee venom allergy",3,0.23219814241486,0.0233063975432453,"HLA-DQB1, HLA-DRB1, HLA-DQA1",1181,3,12971,10.9830651989839,1,0.415192508197618,38.4836377101908]
["GAD_DISEASE","Dermatomyositis|Scleroderma, Systemic|Systemic Scleroderma",3,0.23219814241486,0.0233063975432453,"HLA-DQB1, HLA-DRB1, HLA-DQA1",1181,3,12971,10.9830651989839,1,0.415192508197618,38.4836377101908]
["GAD_DISEASE","Arthritis, Rheumatoid|Pregnancy Complications|Puerperal Disorders|Recurrence|Rheumatoid Arthritis",3,0.23219814241486,0.0233063975432453,"HLA-DQB1, HLA-DRB1, HLA-DQA1",1181,3,12971,10.9830651989839,1,0.415192508197618,38.4836377101908]
["GAD_DISEASE","celiac disease diabetes, type 1",3,0.23219814241486,0.0233063975432453,"HLA-DQB1, HLA-DRB1, HLA-DQA1",1181,3,12971,10.9830651989839,1,0.415192508197618,38.4836377101908]
["GAD_DISEASE","insulin response, first phase; insulitis",3,0.23219814241486,0.0233063975432453,"HLA-DQB1, HLA-DRB1, HLA-DQA1",1181,3,12971,10.9830651989839,1,0.415192508197618,38.4836377101908]
["GAD_DISEASE","inflammatory myopathies",3,0.23219814241486,0.0233063975432453,"HLA-DQB1, HLA-DRB1, HLA-DQA1",1181,3,12971,10.9830651989839,1,0.415192508197618,38.4836377101908]
["GAD_DISEASE","Addison Disease|Autoimmune Diseases",3,0.23219814241486,0.0233063975432453,"HLA-DQB1, HLA-DRB1, HLA-DQA1",1181,3,12971,10.9830651989839,1,0.415192508197618,38.4836377101908]
["GAD_DISEASE","Diabetic Ketoacidosis",3,0.23219814241486,0.0233063975432453,"HLA-DQB1, HLA-DRB1, HLA-DQA1",1181,3,12971,10.9830651989839,1,0.415192508197618,38.4836377101908]
["GAD_DISEASE","Graves' disease; Hashimoto's thyroiditis; autoimmune polyglandular syndrome",3,0.23219814241486,0.0233063975432453,"HLA-DQB1, HLA-DRB1, HLA-DQA1",1181,3,12971,10.9830651989839,1,0.415192508197618,38.4836377101908]
["GAD_DISEASE","hepatitis type 1, autoimmune (AIH-1)",3,0.23219814241486,0.0233063975432453,"HLA-DQB1, HLA-DRB1, HLA-DQA1",1181,3,12971,10.9830651989839,1,0.415192508197618,38.4836377101908]
["GAD_DISEASE","H. pylori infection; Helicobacter pylori infection",3,0.23219814241486,0.0233063975432453,"HLA-DQB1, HLA-DRB1, HLA-DQA1",1181,3,12971,10.9830651989839,1,0.415192508197618,38.4836377101908]
["GAD_DISEASE","autoimmune polyglandular syndrome",3,0.23219814241486,0.0233063975432453,"HLA-DQB1, HLA-DRB1, HLA-DQA1",1181,3,12971,10.9830651989839,1,0.415192508197618,38.4836377101908]
["GAD_DISEASE","warts",3,0.23219814241486,0.0233063975432453,"HLA-DQB1, HLA-DRB1, HLA-DQA1",1181,3,12971,10.9830651989839,1,0.415192508197618,38.4836377101908]
["GAD_DISEASE","Carcinoma|Carcinoma, Squamous Cell|Nasopharyngeal Neoplasms",3,0.23219814241486,0.0233063975432453,"HLA-DQB1, HLA-DRB1, HLA-DQA1",1181,3,12971,10.9830651989839,1,0.415192508197618,38.4836377101908]
["GAD_DISEASE","HIV; sclerosis, systemic",3,0.23219814241486,0.0438127578581207,"HLA-DQB1, HLA-DRB1, HLA-DQA1",1181,4,12971,8.23729889923793,1,0.630065979941808,60.2693790825589]
["GAD_DISEASE","encephalomyelitis",3,0.23219814241486,0.0438127578581207,"HLA-DQB1, HLA-DRB1, HLA-DQA1",1181,4,12971,8.23729889923793,1,0.630065979941808,60.2693790825589]
["GAD_DISEASE","hepatosplenic schistosomiasis japonica",3,0.23219814241486,0.0438127578581207,"HLA-DQB1, HLA-DRB1, HLA-DQA1",1181,4,12971,8.23729889923793,1,0.630065979941808,60.2693790825589]
["GAD_DISEASE","Addison Disease|Addison's disease",3,0.23219814241486,0.0686706773740773,"HLA-DQB1, HLA-DRB1, HLA-DQA1",1181,5,12971,6.58983911939034,1,0.788585717782312,76.9095009968113]
["GAD_DISEASE","multiple sclerosis; diabetes, gestational; insulin; diabetes, type 1; rhinitis",3,0.23219814241486,0.0969200560616097,"HLA-DQB1, HLA-DRB1, HLA-DQA1",1181,6,12971,5.49153259949195,1,0.88780434582701,87.7587799802275]
["GAD_DISEASE","Vogt-Koyanagi-Harada syndrome",3,0.23219814241486,0.526365933639893,"HLA-DQB1, HLA-DRB1, HLA-DQA1",1181,19,12971,1.73416818931324,1,0.999999232147303,99.9999794347007]
[]
["Annotation Cluster 39","Enrichment Score: 1.6345225048098366"]
["Category","Term","Count","%","PValue","Genes","List Total","Pop Hits","Pop Total","Fold Enrichment","Bonferroni","Benjamini","FDR"]
["GAD_DISEASE","Carotid Artery Diseases|Carotid artery stenosis|Carotid Stenosis|Hypertension",4,0.309597523219814,0.0121719200005317,"MMP9, MMP3, MMP2, MMP1",1181,6,12971,7.32204346598927,1,0.250825117332743,22.3001907789742]
["GAD_DISEASE","Alzheimer's disease dementia, vascular",3,0.23219814241486,0.0233063975432453,"MMP9, MMP3, MMP1",1181,3,12971,10.9830651989839,1,0.415192508197618,38.4836377101908]
["GAD_DISEASE","Carcinoma, Hepatocellular|Hepatitis C|Liver Neoplasms",3,0.23219814241486,0.0233063975432453,"MMP9, MMP3, MMP1",1181,3,12971,10.9830651989839,1,0.415192508197618,38.4836377101908]
["GAD_DISEASE","Carotid Artery, Internal, Dissection|",3,0.23219814241486,0.0438127578581207,"MMP9, MMP3, MMP1",1181,4,12971,8.23729889923793,1,0.630065979941808,60.2693790825589]
[]
["Annotation Cluster 40","Enrichment Score: 1.6341229738369987"]
["Category","Term","Count","%","PValue","Genes","List Total","Pop Hits","Pop Total","Fold Enrichment","Bonferroni","Benjamini","FDR"]
["GAD_DISEASE","Birth Weight|Hyperbilirubinemia, Neonatal",4,0.309597523219814,0.0121719200005317,"G6PD, SLCO1B1, UGT1A1, ADA",1181,6,12971,7.32204346598927,1,0.250825117332743,22.3001907789742]
["GAD_DISEASE","Hyperbilirubinemia, Hereditary",3,0.23219814241486,0.0233063975432453,"G6PD, SLCO1B1, UGT1A1",1181,3,12971,10.9830651989839,1,0.415192508197618,38.4836377101908]
["GAD_DISEASE","Hyperbilirubinemia, Neonatal",3,0.23219814241486,0.0233063975432453,"G6PD, SLCO1B1, UGT1A1",1181,3,12971,10.9830651989839,1,0.415192508197618,38.4836377101908]
["GAD_DISEASE","Jaundice, Neonatal|Neonatal Jaundice",3,0.23219814241486,0.0233063975432453,"G6PD, SLCO1B1, UGT1A1",1181,3,12971,10.9830651989839,1,0.415192508197618,38.4836377101908]
["GAD_DISEASE","Glucosephosphate Dehydrogenase Deficiency|Hyperbilirubinemia, Neonatal",3,0.23219814241486,0.0438127578581207,"G6PD, SLCO1B1, UGT1A1",1181,4,12971,8.23729889923793,1,0.630065979941808,60.2693790825589]
[]
["Annotation Cluster 41","Enrichment Score: 1.632524849945646"]
["Category","Term","Count","%","PValue","Genes","List Total","Pop Hits","Pop Total","Fold Enrichment","Bonferroni","Benjamini","FDR"]
["GAD_DISEASE","Colorectal Neoplasms, Hereditary Nonpolyposis|Microsatellite Instability|Rectal Neoplasms",3,0.23219814241486,0.0233063975432453,"KRAS, BRAF, TP53",1181,3,12971,10.9830651989839,1,0.415192508197618,38.4836377101908]
["GAD_DISEASE","Cystadenocarcinoma, Serous|ovarian neoplasm|Ovarian Neoplasms",3,0.23219814241486,0.0233063975432453,"KRAS, BRAF, TP53",1181,3,12971,10.9830651989839,1,0.415192508197618,38.4836377101908]
["GAD_DISEASE","Cystadenocarcinoma, Serous|Ovarian Neoplasms",3,0.23219814241486,0.0233063975432453,"KRAS, BRAF, TP53",1181,3,12971,10.9830651989839,1,0.415192508197618,38.4836377101908]
[]
["Annotation Cluster 42","Enrichment Score: 1.6242958508579934"]
["Category","Term","Count","%","PValue","Genes","List Total","Pop Hits","Pop Total","Fold Enrichment","Bonferroni","Benjamini","FDR"]
["GAD_DISEASE","plasma homocysteine",4,0.309597523219814,0.00280003722742694,"MTHFR, MTR, CBS, MTRR",1181,4,12971,10.9830651989839,0.999999999999955,0.0669034123884211,5.61331953178421]
["GAD_DISEASE","Congenital Heart Defects|Down Syndrome|Heart Defects, Congenital|Heart Septal Defects",4,0.309597523219814,0.00652587858657671,"MTHFR, MTR, CBS, MTRR",1181,5,12971,8.78645215918713,1,0.145374045255921,12.6191139188296]
["GAD_DISEASE","homocysteine metabolism, cognition, and white matter lesions",4,0.309597523219814,0.00652587858657671,"MTHFR, MTR, CBS, MTRR",1181,5,12971,8.78645215918713,1,0.145374045255921,12.6191139188296]
["GAD_DISEASE","Central Nervous System Neoplasms|Central Nervous System Tumors|Lymphoma",4,0.309597523219814,0.0198721362964792,"MTHFR, DHFR, MTR, CBS",1181,7,12971,6.27603725656223,1,0.370216045027357,33.870112521485]
["GAD_DISEASE","Coronary Stenosis|Hyperhomocysteinemia",3,0.23219814241486,0.0233063975432453,"MTHFR, MTR, CBS",1181,3,12971,10.9830651989839,1,0.415192508197618,38.4836377101908]
["GAD_DISEASE","Carcinoma|Neoplasms, Prostatic|Prostatic Neoplasms",3,0.23219814241486,0.0233063975432453,"MTHFR, MTR, CBS",1181,3,12971,10.9830651989839,1,0.415192508197618,38.4836377101908]
["GAD_DISEASE","Edema|Malnutrition",3,0.23219814241486,0.0233063975432453,"MTHFR, MTR, CBS",1181,3,12971,10.9830651989839,1,0.415192508197618,38.4836377101908]
["GAD_DISEASE","Congenital Abnormalities",4,0.309597523219814,0.0296736967160852,"MTHFR, MTR, CBS, MTRR",1181,8,12971,5.49153259949195,1,0.493902162431577,46.2390556747162]
["GAD_DISEASE","Brain Neoplasms|Meningioma",3,0.23219814241486,0.0686706773740773,"MTHFR, MTR, CBS",1181,5,12971,6.58983911939034,1,0.788585717782312,76.9095009968113]
["GAD_DISEASE","breast cancer estrogen progesterone",3,0.23219814241486,0.0969200560616097,"MTHFR, MTR, CBS",1181,6,12971,5.49153259949195,1,0.88780434582701,87.7587799802275]
["GAD_DISEASE","Lymphoma, B-Cell|Lymphoma, Non-Hodgkin|Lymphoma, T-Cell",3,0.23219814241486,0.229127494999829,"MTHFR, MTR, CBS",1181,10,12971,3.29491955969517,1,0.994978189249584,99.5306507436644]
[]
["Annotation Cluster 43","Enrichment Score: 1.595077722795407"]
["Category","Term","Count","%","PValue","Genes","List Total","Pop Hits","Pop Total","Fold Enrichment","Bonferroni","Benjamini","FDR"]
["GAD_DISEASE","Head and Neck Neoplasms|Paraganglioma",4,0.309597523219814,0.00652587858657671,"SDHB, RET, SDHC, SDHD",1181,5,12971,8.78645215918713,1,0.145374045255921,12.6191139188296]
["GAD_DISEASE","Adrenal Gland Neoplasms|Paraganglioma|Pheochromocytoma",4,0.309597523219814,0.00652587858657671,"SDHB, RET, SDHC, SDHD",1181,5,12971,8.78645215918713,1,0.145374045255921,12.6191139188296]
["GAD_DISEASE","Adrenal Gland Neoplasms|Multiple Endocrine Neoplasia Type 2a|Paraganglioma|Pheochromocytoma|von Hippel-Lindau Disease",4,0.309597523219814,0.00652587858657671,"SDHB, RET, SDHC, SDHD",1181,5,12971,8.78645215918713,1,0.145374045255921,12.6191139188296]
["GAD_DISEASE","Adrenal Gland Neoplasms|Pheochromocytoma",4,0.309597523219814,0.0121719200005317,"SDHB, RET, SDHC, SDHD",1181,6,12971,7.32204346598927,1,0.250825117332743,22.3001907789742]
["GAD_DISEASE","Adrenal Gland Neoplasms|Adrenal Neoplasm|Paraganglioma|Pheochromocytoma",4,0.309597523219814,0.0121719200005317,"SDHB, RET, SDHC, SDHD",1181,6,12971,7.32204346598927,1,0.250825117332743,22.3001907789742]
["GAD_DISEASE","pheochtomocytomas",4,0.309597523219814,0.0121719200005317,"SDHB, RET, SDHC, SDHD",1181,6,12971,7.32204346598927,1,0.250825117332743,22.3001907789742]
["GAD_DISEASE","spermatogenesis",4,0.309597523219814,0.0121719200005317,"SDHA, SDHB, SDHC, SDHD",1181,6,12971,7.32204346598927,1,0.250825117332743,22.3001907789742]
["GAD_DISEASE","Paraganglioma",3,0.23219814241486,0.0233063975432453,"SDHB, SDHC, SDHD",1181,3,12971,10.9830651989839,1,0.415192508197618,38.4836377101908]
["GAD_DISEASE","paragangliomas, head and neck",3,0.23219814241486,0.0233063975432453,"SDHB, SDHC, SDHD",1181,3,12971,10.9830651989839,1,0.415192508197618,38.4836377101908]
["GAD_DISEASE","Adrenal Gland Neoplasms|Adrenal Neoplasm|Paraganglioma|Pheochromocytoma|Syndrome",3,0.23219814241486,0.0233063975432453,"SDHB, SDHC, SDHD",1181,3,12971,10.9830651989839,1,0.415192508197618,38.4836377101908]
["GAD_DISEASE","Adrenal Gland Neoplasms|Head and Neck Neoplasms|Paraganglioma|Pheochromocytoma",3,0.23219814241486,0.0438127578581207,"SDHB, RET, SDHD",1181,4,12971,8.23729889923793,1,0.630065979941808,60.2693790825589]
["GAD_DISEASE","pheochromocytomas and paragangliomas",3,0.23219814241486,0.0438127578581207,"SDHB, SDHC, SDHD",1181,4,12971,8.23729889923793,1,0.630065979941808,60.2693790825589]
["GAD_DISEASE","Adrenal Gland Neoplasms|Adrenal Neoplasm|Neoplasms, Multiple Primary|Paraganglioma|Pheochromocytoma",3,0.23219814241486,0.0438127578581207,"SDHB, RET, SDHD",1181,4,12971,8.23729889923793,1,0.630065979941808,60.2693790825589]
["GAD_DISEASE","Adrenal Gland Neoplasms|Carcinoma, Renal Cell|Kidney Neoplasms|Paraganglioma|Pheochromocytoma",3,0.23219814241486,0.0438127578581207,"SDHB, SDHC, SDHD",1181,4,12971,8.23729889923793,1,0.630065979941808,60.2693790825589]
["GAD_DISEASE","pheochromocytoma",3,0.23219814241486,0.0686706773740773,"SDHB, RET, SDHD",1181,5,12971,6.58983911939034,1,0.788585717782312,76.9095009968113]
["OMIM_DISEASE","606864~Paraganglioma and gastric stromal sarcoma",3,0.23219814241486,0.126504325690698,"SDHB, SDHC, SDHD",1056,3,4740,4.48863636363636,1,0.999999999998615,89.9676679921535]
["OMIM_DISEASE","171300~Pheochromocytoma",3,0.23219814241486,0.309471645260209,"SDHB, RET, SDHD",1056,5,4740,2.69318181818181,1,1,99.8154980735021]
[]
["Annotation Cluster 44","Enrichment Score: 1.5829191265152232"]
["Category","Term","Count","%","PValue","Genes","List Total","Pop Hits","Pop Total","Fold Enrichment","Bonferroni","Benjamini","FDR"]
["GAD_DISEASE","sulphamethoxazole hypersensitivity",4,0.309597523219814,0.00652587858657671,"GSTM1, CYP2C9, NAT2, GSTP1",1181,5,12971,8.78645215918713,1,0.145374045255921,12.6191139188296]
["GAD_DISEASE","tobacco consumption",4,0.309597523219814,0.00652587858657671,"GSTM1, CYP1A1, NAT2, GSTP1",1181,5,12971,8.78645215918713,1,0.145374045255921,12.6191139188296]
["GAD_DISEASE","Aneuploidy|Chromosome Aberrations|Chromosome abnormality|Trisomy",4,0.309597523219814,0.0121719200005317,"GSTM1, NAT2, NQO1, GSTP1",1181,6,12971,7.32204346598927,1,0.250825117332743,22.3001907789742]
["GAD_DISEASE","Carcinoma, Transitional Cell|Urologic Neoplasms",4,0.309597523219814,0.0121719200005317,"GSTM1, NAT2, BIRC5, GSTP1",1181,6,12971,7.32204346598927,1,0.250825117332743,22.3001907789742]
["GAD_DISEASE","Cleft Lip|Cleft Palate|Congenital Abnormalities",4,0.309597523219814,0.0121719200005317,"GSTM1, CYP1A1, NAT2, GSTP1",1181,6,12971,7.32204346598927,1,0.250825117332743,22.3001907789742]
["GAD_DISEASE","Cell Transformation, Neoplastic|DNA Damage|Lung Neoplasms|Neoplasm of lung ",3,0.23219814241486,0.0438127578581207,"GSTM1, NAT2, GSTP1",1181,4,12971,8.23729889923793,1,0.630065979941808,60.2693790825589]
["GAD_DISEASE","chemical-related sensitivity",3,0.23219814241486,0.0438127578581207,"GSTM1, NAT2, GSTP1",1181,4,12971,8.23729889923793,1,0.630065979941808,60.2693790825589]
["GAD_DISEASE","Kidney Neoplasms",3,0.23219814241486,0.0438127578581207,"GSTM1, NAT2, GSTP1",1181,4,12971,8.23729889923793,1,0.630065979941808,60.2693790825589]
["GAD_DISEASE","Presbycusis| Hearing Loss",3,0.23219814241486,0.0686706773740773,"GSTM1, NAT2, GSTP1",1181,5,12971,6.58983911939034,1,0.788585717782312,76.9095009968113]
["GAD_DISEASE","motor neuron disease",3,0.23219814241486,0.334103005557153,"GSTM1, NAT2, GSTP1",1181,13,12971,2.53455350745782,1,0.999661269984351,99.9770042800258]
[]
["Annotation Cluster 45","Enrichment Score: 1.5701314764321084"]
["Category","Term","Count","%","PValue","Genes","List Total","Pop Hits","Pop Total","Fold Enrichment","Bonferroni","Benjamini","FDR"]
["GAD_DISEASE","manganism, susceptibility to occupational chronic",4,0.309597523219814,0.0121719200005317,"GSTM1, CYP1A1, CYP2D6, NQO1",1181,6,12971,7.32204346598927,1,0.250825117332743,22.3001907789742]
["GAD_DISEASE","Manganese Poisoning",3,0.23219814241486,0.0233063975432453,"GSTM1, CYP2D6, NQO1",1181,3,12971,10.9830651989839,1,0.415192508197618,38.4836377101908]
["GAD_DISEASE","Leukemia, Myeloid, Acute|Precursor Cell Lymphoblastic Leukemia-Lymphoma|Recurrence",3,0.23219814241486,0.0686706773740773,"GSTM1, CYP2D6, NQO1",1181,5,12971,6.58983911939034,1,0.788585717782312,76.9095009968113]
[]
["Annotation Cluster 46","Enrichment Score: 1.5549811253708623"]
["Category","Term","Count","%","PValue","Genes","List Total","Pop Hits","Pop Total","Fold Enrichment","Bonferroni","Benjamini","FDR"]
["GAD_DISEASE","Disease Susceptibility|Stomach Neoplasms",4,0.309597523219814,0.00652587858657671,"GSTM1, MTHFR, TP53, GSTP1",1181,5,12971,8.78645215918713,1,0.145374045255921,12.6191139188296]
["GAD_DISEASE","Acute Lung Injury|Respiratory Distress Syndrome, Adult",4,0.309597523219814,0.00652587858657671,"GSTM1, MTHFR, SERPINE1, GSTP1",1181,5,12971,8.78645215918713,1,0.145374045255921,12.6191139188296]
["GAD_DISEASE","arsenic metabolism",4,0.309597523219814,0.0296736967160852,"GSTM1, MTHFR, MTR, GSTP1",1181,8,12971,5.49153259949195,1,0.493902162431577,46.2390556747162]
["GAD_DISEASE","Down's syndrome",3,0.23219814241486,0.0438127578581207,"GSTM1, MTHFR, GSTP1",1181,4,12971,8.23729889923793,1,0.630065979941808,60.2693790825589]
["GAD_DISEASE","Arsenic Poisoning|Skin Diseases",3,0.23219814241486,0.0438127578581207,"GSTM1, MTHFR, GSTP1",1181,4,12971,8.23729889923793,1,0.630065979941808,60.2693790825589]
["GAD_DISEASE","Drug-Induced Liver Injury|Precursor Cell Lymphoblastic Leukemia-Lymphoma",4,0.309597523219814,0.0554456718634368,"GSTM1, MTHFR, GSTP1, ABCG2",1181,10,12971,4.39322607959356,1,0.715196693770559,69.1255310393718]
["GAD_DISEASE","Drug-Induced Liver Injury|Liver Diseases",3,0.23219814241486,0.0969200560616097,"GSTM1, MTHFR, GSTP1",1181,6,12971,5.49153259949195,1,0.88780434582701,87.7587799802275]
[]
["Annotation Cluster 47","Enrichment Score: 1.553393447655079"]
["Category","Term","Count","%","PValue","Genes","List Total","Pop Hits","Pop Total","Fold Enrichment","Bonferroni","Benjamini","FDR"]
["GAD_DISEASE","clopidogrel ",4,0.309597523219814,0.00652587858657671,"CYP3A4, CYP2B6, CYP2C9, CYP1A2",1181,5,12971,8.78645215918713,1,0.145374045255921,12.6191139188296]
["GAD_DISEASE","methadone levels",4,0.309597523219814,0.0198721362964792,"CYP2B6, CYP2C9, ABCB1, CYP1A2",1181,7,12971,6.27603725656223,1,0.370216045027357,33.870112521485]
["GAD_DISEASE","Acute Coronary Syndrome|Cardiovascular Diseases|Thrombosis",3,0.23219814241486,0.0686706773740773,"CYP2B6, CYP2C9, CYP1A2",1181,5,12971,6.58983911939034,1,0.788585717782312,76.9095009968113]
["GAD_DISEASE","Cardiovascular Diseases|Myocardial Infarction|Stroke",3,0.23219814241486,0.0686706773740773,"CYP2B6, CYP2C9, CYP1A2",1181,5,12971,6.58983911939034,1,0.788585717782312,76.9095009968113]
[]
["Annotation Cluster 48","Enrichment Score: 1.541824487352505"]
["Category","Term","Count","%","PValue","Genes","List Total","Pop Hits","Pop Total","Fold Enrichment","Bonferroni","Benjamini","FDR"]
["GAD_DISEASE","von Willebrand Disease",4,0.309597523219814,0.00652587858657671,"VWF, MTHFR, F2, ITGB3",1181,5,12971,8.78645215918713,1,0.145374045255921,12.6191139188296]
["GAD_DISEASE","Atherosclerosis|Hyperlipidemias|Hypertension|Optic Neuropathy, Ischemic|Thrombophilia",4,0.309597523219814,0.00652587858657671,"ACE, MTHFR, F2, ITGB3",1181,5,12971,8.78645215918713,1,0.145374045255921,12.6191139188296]
["GAD_DISEASE","polycystic ovary syndrome; pregnancy loss, recurrent",4,0.309597523219814,0.00652587858657671,"MTHFR, F2, SERPINE1, ITGB3",1181,5,12971,8.78645215918713,1,0.145374045255921,12.6191139188296]
["GAD_DISEASE","Atherosclerosis|Pregnancy Complications, Cardiovascular|Pregnancy Complications, Hematologic|Retinal Artery Occlusion|Retinal Vein Occlusion|Thrombophilia|Thrombosis",4,0.309597523219814,0.00652587858657671,"MTHFR, F2, SERPINE1, ITGB3",1181,5,12971,8.78645215918713,1,0.145374045255921,12.6191139188296]
["GAD_DISEASE","obesity; retinal vascular occlusion",4,0.309597523219814,0.0121719200005317,"MTHFR, F2, SERPINE1, ITGB3",1181,6,12971,7.32204346598927,1,0.250825117332743,22.3001907789742]
["GAD_DISEASE","Brain Ischemia|Recurrence|Stroke",4,0.309597523219814,0.0415558424226315,"MTHFR, F2, ITGB3, ITGA2B",1181,9,12971,4.88136231065951,1,0.610936466450014,58.2919211685126]
["GAD_DISEASE","Epistaxis|Thrombasthenia",3,0.23219814241486,0.0438127578581207,"MTHFR, F2, ITGB3",1181,4,12971,8.23729889923793,1,0.630065979941808,60.2693790825589]
["GAD_DISEASE","Brain Ischemia|Intracranial Thrombosis|Ischemic Attack, Transient|Migraine Disorders|Stroke",3,0.23219814241486,0.0438127578581207,"MTHFR, F2, ITGB3",1181,4,12971,8.23729889923793,1,0.630065979941808,60.2693790825589]
["GAD_DISEASE","atrial fibrillation stroke, ischemic",3,0.23219814241486,0.0438127578581207,"MTHFR, F2, ITGB3",1181,4,12971,8.23729889923793,1,0.630065979941808,60.2693790825589]
["GAD_DISEASE","Cardiovascular Diseases|Hearing Loss, Sensorineural|Hearing Loss, Sudden",3,0.23219814241486,0.0438127578581207,"MTHFR, F2, ITGB3",1181,4,12971,8.23729889923793,1,0.630065979941808,60.2693790825589]
["GAD_DISEASE","Abortion, Habitual|Thrombophilia",3,0.23219814241486,0.0686706773740773,"MTHFR, F2, ITGB3",1181,5,12971,6.58983911939034,1,0.788585717782312,76.9095009968113]
["GAD_DISEASE","fibrinogen protein C resistance ratio prothrombin thrombosis, deep vein",3,0.23219814241486,0.0969200560616097,"F2, SERPINE1, ITGB3",1181,6,12971,5.49153259949195,1,0.88780434582701,87.7587799802275]
["GAD_DISEASE","hearing loss, sensorineural nonsyndromic",3,0.23219814241486,0.40192699203356,"MTHFR, F2, ITGB3",1181,15,12971,2.19661303979678,1,0.999949247686815,99.9974854745183]
[]
["Annotation Cluster 49","Enrichment Score: 1.5126540132838335"]
["Category","Term","Count","%","PValue","Genes","List Total","Pop Hits","Pop Total","Fold Enrichment","Bonferroni","Benjamini","FDR"]
["GAD_DISEASE","polycystic ovary syndrome; pregnancy loss, recurrent",4,0.309597523219814,0.00652587858657671,"MTHFR, F2, SERPINE1, ITGB3",1181,5,12971,8.78645215918713,1,0.145374045255921,12.6191139188296]
["GAD_DISEASE","Atherosclerosis|Pregnancy Complications, Cardiovascular|Pregnancy Complications, Hematologic|Retinal Artery Occlusion|Retinal Vein Occlusion|Thrombophilia|Thrombosis",4,0.309597523219814,0.00652587858657671,"MTHFR, F2, SERPINE1, ITGB3",1181,5,12971,8.78645215918713,1,0.145374045255921,12.6191139188296]
["GAD_DISEASE","obesity; retinal vascular occlusion",4,0.309597523219814,0.0121719200005317,"MTHFR, F2, SERPINE1, ITGB3",1181,6,12971,7.32204346598927,1,0.250825117332743,22.3001907789742]
["GAD_DISEASE","Behcet Syndrome|Thrombosis",4,0.309597523219814,0.0121719200005317,"MTHFR, F2, SERPINE1, IRF1",1181,6,12971,7.32204346598927,1,0.250825117332743,22.3001907789742]
["GAD_DISEASE","Thrombophilia|Venous Thrombosis",4,0.309597523219814,0.0296736967160852,"MTHFR, THBD, F2, SERPINE1",1181,8,12971,5.49153259949195,1,0.493902162431577,46.2390556747162]
["GAD_DISEASE","Carcinoma, Hepatocellular|Liver Cirrhosis|Thrombosis",3,0.23219814241486,0.0438127578581207,"MTHFR, F2, SERPINE1",1181,4,12971,8.23729889923793,1,0.630065979941808,60.2693790825589]
["GAD_DISEASE","thrombosis, cerebral",3,0.23219814241486,0.0438127578581207,"MTHFR, F2, SERPINE1",1181,4,12971,8.23729889923793,1,0.630065979941808,60.2693790825589]
["GAD_DISEASE","Budd-Chiari syndrome liver transplant portal vein thrombosis",3,0.23219814241486,0.0438127578581207,"MTHFR, F2, SERPINE1",1181,4,12971,8.23729889923793,1,0.630065979941808,60.2693790825589]
["GAD_DISEASE","fetal loss | thrombophilia",3,0.23219814241486,0.0438127578581207,"MTHFR, F2, SERPINE1",1181,4,12971,8.23729889923793,1,0.630065979941808,60.2693790825589]
["GAD_DISEASE","Hearing Loss, Sudden|Thrombosis",3,0.23219814241486,0.0686706773740773,"MTHFR, F2, SERPINE1",1181,5,12971,6.58983911939034,1,0.788585717782312,76.9095009968113]
["GAD_DISEASE","preeclampsia; hypertension, gestational",3,0.23219814241486,0.0686706773740773,"MTHFR, F2, SERPINE1",1181,5,12971,6.58983911939034,1,0.788585717782312,76.9095009968113]
["GAD_DISEASE","Recurrence|Thrombophilia|Venous Thrombosis",3,0.23219814241486,0.0686706773740773,"MTHFR, F2, SERPINE1",1181,5,12971,6.58983911939034,1,0.788585717782312,76.9095009968113]
["GAD_DISEASE","fibrinogen protein C resistance ratio prothrombin thrombosis, deep vein",3,0.23219814241486,0.0969200560616097,"F2, SERPINE1, ITGB3",1181,6,12971,5.49153259949195,1,0.88780434582701,87.7587799802275]
[]
["Annotation Cluster 50","Enrichment Score: 1.5009538294984341"]
["Category","Term","Count","%","PValue","Genes","List Total","Pop Hits","Pop Total","Fold Enrichment","Bonferroni","Benjamini","FDR"]
["GAD_DISEASE","tobacco consumption",4,0.309597523219814,0.00652587858657671,"GSTM1, CYP1A1, NAT2, GSTP1",1181,5,12971,8.78645215918713,1,0.145374045255921,12.6191139188296]
["GAD_DISEASE","Leukemia|Prenatal Exposure Delayed Effects",4,0.309597523219814,0.00652587858657671,"GSTM1, CYP1A1, NQO1, GSTP1",1181,5,12971,8.78645215918713,1,0.145374045255921,12.6191139188296]
["GAD_DISEASE","phenanthrene metabolite ratios, urinary",4,0.309597523219814,0.00652587858657671,"GSTM1, CYP1B1, CYP1A1, GSTP1",1181,5,12971,8.78645215918713,1,0.145374045255921,12.6191139188296]
["GAD_DISEASE","Birth Weight|Fetal Growth Retardation",4,0.309597523219814,0.00652587858657671,"GSTM1, CYP1A1, CYP2D6, GSTP1",1181,5,12971,8.78645215918713,1,0.145374045255921,12.6191139188296]
["GAD_DISEASE","Adenocarcinoma|Esophageal Neoplasms|Oesophageal neoplasm|Stomach Neoplasms",4,0.309597523219814,0.0121719200005317,"GSTM1, CYP1A1, ADH1C, GSTP1",1181,6,12971,7.32204346598927,1,0.250825117332743,22.3001907789742]
["GAD_DISEASE","Alcoholism|Liver Cirrhosis, Alcoholic|Pancreatitis, Alcoholic",4,0.309597523219814,0.0121719200005317,"GSTM1, CYP1A1, ADH1C, GSTP1",1181,6,12971,7.32204346598927,1,0.250825117332743,22.3001907789742]
["GAD_DISEASE","Adenocarcinoma|Carcinoma, Squamous Cell|Esophageal Neoplasms|Oesophageal neoplasm|Squamous cell carcinoma",4,0.309597523219814,0.0121719200005317,"GSTM1, CYP1A1, TP53, GSTP1",1181,6,12971,7.32204346598927,1,0.250825117332743,22.3001907789742]
["GAD_DISEASE","Cleft Lip|Cleft Palate|Congenital Abnormalities",4,0.309597523219814,0.0121719200005317,"GSTM1, CYP1A1, NAT2, GSTP1",1181,6,12971,7.32204346598927,1,0.250825117332743,22.3001907789742]
["GAD_DISEASE","lymphoma; Hodgkin's disease",4,0.309597523219814,0.0198721362964792,"GSTM1, CYP1A1, NQO1, GSTP1",1181,7,12971,6.27603725656223,1,0.370216045027357,33.870112521485]
["GAD_DISEASE","Leukoplakia, Oral",4,0.309597523219814,0.0198721362964792,"GSTM1, CCND1, CYP1A1, GSTP1",1181,7,12971,6.27603725656223,1,0.370216045027357,33.870112521485]
["GAD_DISEASE","Skin Diseases",4,0.309597523219814,0.0415558424226315,"GSTM1, CYP1A1, TPMT, GSTP1",1181,9,12971,4.88136231065951,1,0.610936466450014,58.2919211685126]
["GAD_DISEASE","Carcinoma, Squamous Cell|Esophageal Neoplasms|Oesophageal neoplasm|Squamous cell carcinoma|Stomach Neoplasms",3,0.23219814241486,0.0438127578581207,"GSTM1, CYP1A1, GSTP1",1181,4,12971,8.23729889923793,1,0.630065979941808,60.2693790825589]
["GAD_DISEASE","Adenocarcinoma|Barrett Esophagus|Esophageal Neoplasms|",3,0.23219814241486,0.0438127578581207,"GSTM1, CYP1A1, GSTP1",1181,4,12971,8.23729889923793,1,0.630065979941808,60.2693790825589]
["GAD_DISEASE","esophageal carcinoma",3,0.23219814241486,0.0686706773740773,"GSTM1, CYP1A1, GSTP1",1181,5,12971,6.58983911939034,1,0.788585717782312,76.9095009968113]
["GAD_DISEASE","Carcinoma, Squamous Cell|Head and Neck Neoplasms|Laryngeal neoplasm|Laryngeal Neoplasms|Mouth Neoplasms|Pharyngeal Neoplasms|Squamous cell carcinoma",3,0.23219814241486,0.0686706773740773,"GSTM1, CYP1A1, GSTP1",1181,5,12971,6.58983911939034,1,0.788585717782312,76.9095009968113]
["GAD_DISEASE","Hodgkin's disease; non-Hodgkin's lymphoma",3,0.23219814241486,0.0969200560616097,"GSTM1, CYP1A1, GSTP1",1181,6,12971,5.49153259949195,1,0.88780434582701,87.7587799802275]
["GAD_DISEASE","Chromosome Aberrations|Chromosome abnormality|DNA Damage",3,0.23219814241486,0.0969200560616097,"GSTM1, CYP1A1, NQO1",1181,6,12971,5.49153259949195,1,0.88780434582701,87.7587799802275]
["GAD_DISEASE","vinyl chloride",3,0.23219814241486,0.0969200560616097,"GSTM1, CYP1A1, GSTP1",1181,6,12971,5.49153259949195,1,0.88780434582701,87.7587799802275]
["GAD_DISEASE","DNA damage, biomarkers of",3,0.23219814241486,0.0969200560616097,"GSTM1, CYP1A1, GSTP1",1181,6,12971,5.49153259949195,1,0.88780434582701,87.7587799802275]
["GAD_DISEASE","encephalopathy, solvent-induced",3,0.23219814241486,0.0969200560616097,"GSTM1, CYP1A1, GSTP1",1181,6,12971,5.49153259949195,1,0.88780434582701,87.7587799802275]
["GAD_DISEASE","bronchitis; pneumonia",3,0.23219814241486,0.0969200560616097,"GSTM1, CYP1A1, GSTP1",1181,6,12971,5.49153259949195,1,0.88780434582701,87.7587799802275]
["GAD_DISEASE","Peripheral Nervous System Diseases",3,0.23219814241486,0.194391130369636,"GSTM1, CYP1A1, GSTP1",1181,9,12971,3.66102173299463,1,0.988671742737334,98.836213915232]
[]
["Annotation Cluster 51","Enrichment Score: 1.4684057744897538"]
["Category","Term","Count","%","PValue","Genes","List Total","Pop Hits","Pop Total","Fold Enrichment","Bonferroni","Benjamini","FDR"]
["GAD_DISEASE","Ovarian Failure, Premature|POF - Premature ovarian failure",4,0.309597523219814,0.0121719200005317,"AR, ESR1, ESR2, FSHR",1181,6,12971,7.32204346598927,1,0.250825117332743,22.3001907789742]
["GAD_DISEASE","colon cancer; rectal cancer",3,0.23219814241486,0.0233063975432453,"AR, ESR1, ESR2",1181,3,12971,10.9830651989839,1,0.415192508197618,38.4836377101908]
["GAD_DISEASE","Cryptorchidism|Hypospadias",3,0.23219814241486,0.0686706773740773,"AR, ESR1, ESR2",1181,5,12971,6.58983911939034,1,0.788585717782312,76.9095009968113]
["GAD_DISEASE","androgen levels",3,0.23219814241486,0.0686706773740773,"AR, ESR1, ESR2",1181,5,12971,6.58983911939034,1,0.788585717782312,76.9095009968113]
[]
["Annotation Cluster 52","Enrichment Score: 1.413699416004456"]
["Category","Term","Count","%","PValue","Genes","List Total","Pop Hits","Pop Total","Fold Enrichment","Bonferroni","Benjamini","FDR"]
["GAD_DISEASE","Birth Weight|Respiratory Distress Syndrome, Newborn",4,0.309597523219814,0.0121719200005317,"GSTM1, ABCB1, NR3C1, GSTP1",1181,6,12971,7.32204346598927,1,0.250825117332743,22.3001907789742]
["GAD_DISEASE","Alcoholism|Head and Neck Neoplasms",3,0.23219814241486,0.0686706773740773,"GSTM1, ABCB1, GSTP1",1181,5,12971,6.58983911939034,1,0.788585717782312,76.9095009968113]
["GAD_DISEASE","docetaxel pharmacokinetics docetaxel toxicity",3,0.23219814241486,0.0686706773740773,"GSTM1, ABCB1, GSTP1",1181,5,12971,6.58983911939034,1,0.788585717782312,76.9095009968113]
[]
["Annotation Cluster 53","Enrichment Score: 1.4077945067107775"]
["Category","Term","Count","%","PValue","Genes","List Total","Pop Hits","Pop Total","Fold Enrichment","Bonferroni","Benjamini","FDR"]
["GAD_DISEASE","nausea",4,0.309597523219814,0.0198721362964792,"SLC6A4, CYP2D6, HTR3A, HTR2A",1181,7,12971,6.27603725656223,1,0.370216045027357,33.870112521485]
["GAD_DISEASE","depression drug hypersensitivity",3,0.23219814241486,0.0438127578581207,"SLC6A4, HTR3A, HTR2A",1181,4,12971,8.23729889923793,1,0.630065979941808,60.2693790825589]
["GAD_DISEASE","harm avoidance",3,0.23219814241486,0.0686706773740773,"SLC6A4, HTR3A, HTR2A",1181,5,12971,6.58983911939034,1,0.788585717782312,76.9095009968113]
[]
["Annotation Cluster 54","Enrichment Score: 1.406403280200286"]
["Category","Term","Count","%","PValue","Genes","List Total","Pop Hits","Pop Total","Fold Enrichment","Bonferroni","Benjamini","FDR"]
["GAD_DISEASE","medicamentosa-like dermatitis, trichloroethylene",3,0.23219814241486,0.0233063975432453,"ADH1C, ALDH2, ADH1B",1181,3,12971,10.9830651989839,1,0.415192508197618,38.4836377101908]
["GAD_DISEASE","Carcinoma, Squamous Cell|Mouth Neoplasms|Pharyngeal Neoplasms|Squamous cell carcinoma",3,0.23219814241486,0.0233063975432453,"ADH1C, ALDH2, ADH1B",1181,3,12971,10.9830651989839,1,0.415192508197618,38.4836377101908]
["GAD_DISEASE","alcohol abuse cirrhosis, alcoholic pancreatitis, chronic",3,0.23219814241486,0.0233063975432453,"ADH1C, ALDH2, ADH1B",1181,3,12971,10.9830651989839,1,0.415192508197618,38.4836377101908]
["GAD_DISEASE","cirrhosis; pancreatitis; esophageal cancer",3,0.23219814241486,0.0438127578581207,"ADH1C, ALDH2, ADH1B",1181,4,12971,8.23729889923793,1,0.630065979941808,60.2693790825589]
["GAD_DISEASE","Alcoholic Intoxication, Chronic|Drug Allergy",3,0.23219814241486,0.0438127578581207,"ADH1C, ALDH2, ADH1B",1181,4,12971,8.23729889923793,1,0.630065979941808,60.2693790825589]
["GAD_DISEASE","Alcoholic Liver Diseases|Alcoholism|Liver Diseases, Alcoholic",3,0.23219814241486,0.0438127578581207,"ADH1C, ALDH2, ADH1B",1181,4,12971,8.23729889923793,1,0.630065979941808,60.2693790825589]
["GAD_DISEASE","Alcoholism|Bone necrosis|Liver Cirrhosis|Osteonecrosis|Pancreatitis, Alcoholic",3,0.23219814241486,0.0438127578581207,"ADH1C, ALDH2, ADH1B",1181,4,12971,8.23729889923793,1,0.630065979941808,60.2693790825589]
["GAD_DISEASE","Alcoholism|Diseases in Twins|Flushing",3,0.23219814241486,0.0686706773740773,"ADH1C, ALDH2, ADH1B",1181,5,12971,6.58983911939034,1,0.788585717782312,76.9095009968113]
["GAD_DISEASE","Coronary Disease|Coronary heart disease|Diabetes mellitus",3,0.23219814241486,0.0686706773740773,"ADH1C, ALDH2, ADH1B",1181,5,12971,6.58983911939034,1,0.788585717782312,76.9095009968113]
[]
["Annotation Cluster 55","Enrichment Score: 1.2721961423262649"]
["Category","Term","Count","%","PValue","Genes","List Total","Pop Hits","Pop Total","Fold Enrichment","Bonferroni","Benjamini","FDR"]
["GAD_DISEASE","dose of nevirapine or efavirenz",3,0.23219814241486,0.0438127578581207,"CYP3A4, CYP2B6, ABCB1",1181,4,12971,8.23729889923793,1,0.630065979941808,60.2693790825589]
["GAD_DISEASE","efavirenz pharmacokinetics",3,0.23219814241486,0.0438127578581207,"CYP3A4, CYP2B6, ABCB1",1181,4,12971,8.23729889923793,1,0.630065979941808,60.2693790825589]
["GAD_DISEASE","Efavirenz ",3,0.23219814241486,0.0438127578581207,"CYP3A4, CYP2B6, ABCB1",1181,4,12971,8.23729889923793,1,0.630065979941808,60.2693790825589]
["GAD_DISEASE","Nevirapine",3,0.23219814241486,0.0969200560616097,"CYP3A4, CYP2B6, ABCB1",1181,6,12971,5.49153259949195,1,0.88780434582701,87.7587799802275]