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{"sheet":"Suppl table 1","index":0,"n_rows":35,"n_cols":34,"rows_kept":35,"merged":[[3,4,3,21],[3,22,3,26],[3,27,3,33]]}
["Within-host microevolution of eight time-serial isolates from a patient with multidrug-resistant tuberculosis and inadequate compliance to treatment"]
["Supplementary table 2"]
[]
[{"$nulls":4},"Phenotypic drug susceptibility testing",{"$nulls":17},"MAS-PCR",{"$nulls":4},"Genomic resistance prediction \n(alternative_allele_depth:wt_allele_depth)"]
[null,"isolate ID","Sample Date","Hospital","INH ","RIF","PZA","EMB","STR","KAN","AMK","CPM","OFX","LVX","MFX \n(0.5 ug/ml)","MXF \n(2 ug/ml)","MXF \n(MIC)","ETH","Cs","PAS","LNZ","CFZ","katg \n(S315T)","inhA \n(C-15T)","rpoB \nD435V","rpoB \n(X445X)","rpoB \n(X450X)","INH","RIF","PZA","STR","ETH","FLQs","CFZ-BDQ"]
[20079,"TB1","2011-08-01",1,"R","R","S","S","R","S","S","S","S","S","nd","nd","nd","NI","S","S","nd","nd","R","S","R","S","S","katG S315T (112:0)","rpoB D435V \n(89:0)",null,"rrs C517T\n(148:0)"]
[20678,"TB2","2011-11-01",1,"R","R","nd","nd","nd","nd","nd","nd","nd","nd","nd","nd","nd","nd","nd","nd","nd","nd","R","S","R","S","S","katG S315T \n(138:0)","rpoB D435V \n(133:0)",null,"rrs C517T \n(235:1)"]
[20651,"TB3","2012-03-01",1,"R","R","S","S","R","S","S","S","R","R","nd","nd","nd","S","S","S","nd","nd","R","S","R","S","S","katG S315T \n(107:0)","rpoB D435V \n(102:0)",null,"rrs C517T \n(145:0)",null,"gyrA D94H \n(77:0)"]
[20793,"TB4","2012-03-01",1,"R","R","nd","nd","nd","nd","nd","nd","nd","nd","nd","nd","nd","nd","nd","nd","nd","nd","R","S","R","S","S","katG S315T \n(94:0)","rpoB D435V \n(96:0)",null,"rrs C517T \n(150:0)",null,"gyrA D94H \n(82:0)"]
[21471,"TB5","2012-12-01",2,"R","R","nd","nd","nd","nd","nd","nd","nd","nd","nd","nd","nd","nd","nd","nd","nd","nd","R","S","R","S","S","katG S315T \n(38:0)","rpoB D435V \n(46:0)",null,"rrs C517T \n(52:0)",null,"gyrA D94H \n(32:0)"]
[22457,"TB6","2013-10-01",2,"R","R","S","S","R","S","S","S","R","R","nd","nd","R","S","nd","nd","S","S","R","S","R","S","S","katG S315T \n(106:0)","rpoB D435V \n(97:0)",null,"rrs C517T \n(160:0)",null,"gyrA A90V \n(80:14)"]
[25593,"TB7","2016-01-01",2,"R","R","R","S","R","S","S","S","nd","R","R","S","nd","S","S","S","S","R","R","S","R","S","S","katG S315T \n(59:0)","rpoB D435V \n(69:0)","pncA T177fs \n(50:0)","rrs C517T \n(121:0)","ethA Thr88fs\n(128:128)","gyrA D94H \n(50:0)","Rv0678 D47fs \n(34:11)"]
[30753,"TB8","2016-05-01",2,"R","R","R","nd","nd","nd","nd","nd","nd","nd","R","R","R","nd","nd","nd","nd","R","R","S","R","S","S","katG S315T \n(63:0)","rpoB D435V \n(63:0)","pncA T177fs \n(31:0)","rrs C517T \n(90:0)","ethA Thr88fs\n(86:8)","gyrA D94H \n(63:0)","Rv0678 D47fs \n(15:23)"]
[]
[null,null,"nd= not done"]
[null,null,"NI= no interpretable"]
[null,null,"R= resistant"]
[null,null,"S= susceptible"]
[null,null,"INH= isoniazid"]
[null,null,"RIF: rifampicin"]
[null,null,"PZA:p yrazimanicin"]
[null,null,"EMB= ethambutol"]
[null,null,"STR= streptomicin"]
[null,null,"KAN= kanamicin"]
[null,null,"AMK= amikacin"]
[null,null,"CPM= capreomicin"]
[null,null,"OFX= ofloxacin"]
[null,null,"LVX= levofloxacin"]
[null,null,"MFX= moxifloxacin \n(0.5 ug/ml)"]
[null,null,"ETH= ethionamide"]
[null,null,"Cs= cycloserine"]
[null,null,"PAS= ac. "]
[null,null,"LNZ= linezolid"]
[null,null,"CFM= clofazimine"]
[null,null,"FLQs=  fluoroquinolones"]