{"text_format":"3","workbook":"xls","n_sheets":2,"sheets":["GSVA_KC_Keratinocyte_basal_LAMB","GSVA_FB_DCN_ZNF90_Limma_1"],"read":"whole","date_system":"1900","formulas":"cached_only"}

{"sheet":"GSVA_KC_Keratinocyte_basal_LAMB","index":0,"n_rows":2966,"n_cols":9,"rows_kept":2966,"flags":["formulas_cached_only"]}
[null,"id","t","log2FC","adj.P.Val","P.Value","AveExpr","B","threshold"]
[1,"WP_COVID19_THROMBOSIS_AND_ANTICOAGULATION",-27.6278104518772,-0.180852201998947,{"v":6.94167385275394e-160,"d":"6.94E-160"},{"v":2.34199522697501e-163,"d":"2.34E-163"},0.529746650618659,362.497370689053,"Down"]
[2,"REACTOME_HIGHLY_SODIUM_PERMEABLE_POSTSYNAPTIC_ACETYLCHOLINE_NICOTINIC_RECEPTORS",-25.9950158958471,-0.155063730356407,{"v":3.88001027186121e-142,"d":"3.88E-142"},{"v":2.61809060179569e-145,"d":"2.62E-145"},0.477871171452056,321.086993282341,"Down"]
[3,"REACTOME_DOPAMINE_RECEPTORS",-25.58979386553,-0.149152751782975,{"v":5.48436272268674e-138,"d":"5.48E-138"},{"v":5.55097441567484e-141,"d":"5.55E-141"},0.371165506431917,311.161517509716,"Down"]
[4,"REACTOME_DEFECTIVE_CSF2RB_CAUSES_SMDP5",-23.5067105049089,-0.13402160172045,{"v":7.58656128561345e-117,"d":"7.59E-117"},{"v":1.02382743395593e-119,"d":"1.02E-119"},0.444531712338393,262.381082745861,"Down"]
[5,"REACTOME_TACHYKININ_RECEPTORS_BIND_TACHYKININS",-22.0864810479398,-0.121424468410434,{"v":1.79581365974848e-103,"d":"1.80E-103"},{"v":3.63525032337749e-106,"d":"3.64E-106"},0.581835267571897,231.306591651871,"Down"]
[6,"REACTOME_MISCELLANEOUS_SUBSTRATES",-21.5217089252219,-0.157298174137168,{"v":1.77778556259496e-98,"d":"1.78E-98"},{"v":5.39813429937742e-101,"d":"5.40E-101"},0.102884295235945,219.448484998017,"Down"]
[7,"REACTOME_DISEASES_ASSOCIATED_WITH_SURFACTANT_METABOLISM",-21.3264088912382,-0.105033119070628,{"v":8.36024127729716e-97,"d":"8.36E-97"},{"v":3.10265364542067e-99,"d":"3.10E-99"},0.392577017086277,215.41447644902,"Down"]
[8,"BIOCARTA_BLYMPHOCYTE_PATHWAY",-20.8602690940529,-0.144621446077133,{"v":8.44849233394116e-93,"d":"8.45E-93"},{"v":4.27555280057751e-95,"d":"4.28E-95"},0.176785748285987,205.924959955775,"Down"]
[9,"REACTOME_RELAXIN_RECEPTORS",-20.7583188123546,-0.150742557299398,{"v":6.20450252802726e-92,"d":"6.20E-92"},{"v":3.34925912444117e-94,"d":"3.35E-94"},0.291928283452514,203.875628437369,"Down"]
[10,"REACTOME_EICOSANOIDS",-20.6123964882919,-0.169800882926275,{"v":1.03271203641422e-90,"d":"1.03E-90"},{"v":6.27153058551143e-93,"d":"6.27E-93"},0.11933547956076,200.958762869555,"Down"]
[11,"BIOCARTA_TCRA_PATHWAY",-20.4609706492563,-0.106419309754338,{"v":2.0047497601700602e-89,"d":"2.00E-89"},{"v":1.28509600010901e-91,"d":"1.29E-91"},0.303016364688153,197.95227829433,"Down"]
[12,"REACTOME_PRESYNAPTIC_NICOTINIC_ACETYLCHOLINE_RECEPTORS",-19.8532424087457,-0.0776686291541326,{"v":2.57763105185241e-84,"d":"2.58E-84"},{"v":1.91322142850044e-86,"d":"1.91E-86"},0.421638660762072,186.095665225484,"Down"]
[13,"REACTOME_SEROTONIN_AND_MELATONIN_BIOSYNTHESIS",-19.1800965028605,-0.0939570780800112,{"v":7.60717917100008e-79,"d":"7.61E-79"},{"v":6.92961665374501e-81,"d":"6.93E-81"},0.599291699656724,173.3560555611,"Down"]
[14,"REACTOME_XENOBIOTICS",-19.1602126150564,-0.103019678267086,{"v":1.02720035721788e-78,"d":"1.03E-78"},{"v":1.00502059241965e-80,"d":"1.01E-80"},0.113799429748036,172.986053389065,"Down"]
[15,"BIOCARTA_THELPER_PATHWAY",-18.790022395777,-0.0800787884514515,{"v":8.94179751638762e-76,"d":"8.94E-76"},{"v":9.53886035284038e-78,"d":"9.54E-78"},0.48478021921428,166.163829120909,"Down"]
[16,"REACTOME_PROSTANOID_LIGAND_RECEPTORS",-18.61960058073,-0.0828660268876299,{"v":1.87133348914999e-74,"d":"1.87E-74"},{"v":2.14660386744601e-76,"d":"2.15E-76"},0.413886398260813,163.065517388733,"Down"]
[17,"REACTOME_LIGAND_RECEPTOR_INTERACTIONS",-18.2325367270564,-0.210114567343989,{"v":1.78614467618816e-71,"d":"1.79E-71"},{"v":2.2899290720361e-73,"d":"2.29E-73"},-0.0565638336252956,156.128133940457,"Down"]
[18,"REACTOME_KETONE_BODY_METABOLISM",-18.1183547282237,-0.154503101775483,{"v":1.32564283682231e-70,"d":"1.33E-70"},{"v":1.74426689055567e-72,"d":"1.74E-72"},-0.0848391424710504,154.108088745043,"Down"]
[19,"REACTOME_FATTY_ACIDS",-17.8884001496774,-0.168868108874205,{"v":7.08287408434848e-69,"d":"7.08E-69"},{"v":1.00364612531254e-70,"d":"1.00E-70"},0.00515953631314364,150.076504714074,"Down"]
[20,"REACTOME_EICOSANOID_LIGAND_BINDING_RECEPTORS",-17.7844299291312,-0.102578378896135,{"v":4.15684768835343e-68,"d":"4.16E-68"},{"v":6.17075905153681e-70,"d":"6.17E-70"},0.261599941167061,148.26978654643,"Down"]
[21,"REACTOME_CLASS_C_3_METABOTROPIC_GLUTAMATE_PHEROMONE_RECEPTORS",-17.7164083535227,-0.0522775764683316,{"v":1.32643683376388e-67,"d":"1.33E-67"},{"v":2.01382110389254e-69,"d":"2.01E-69"},0.519405066893737,147.093187713333,"Down"]
[22,"REACTOME_CYTOCHROME_P450_ARRANGED_BY_SUBSTRATE_TYPE",-16.7301454065853,-0.0640817727469111,{"v":1.75023955462551e-60,"d":"1.75E-60"},{"v":3.48394513235172e-62,"d":"3.48E-62"},0.0174326236168281,130.517483075806,"Down"]
[23,"BIOCARTA_TCAPOPTOSIS_PATHWAY",-16.4762933896189,-0.0839305006061963,{"v":1.03233353644934e-58,"d":"1.03E-58"},{"v":2.19423120095508e-60,"d":"2.19E-60"},0.458900457969639,126.398168902123,"Down"]
[24,"REACTOME_RESOLUTION_OF_D_LOOP_STRUCTURES",-16.3013696283689,-0.0816582098853972,{"v":1.60398967638568e-57,"d":"1.60E-57"},{"v":3.67986835338145e-59,"d":"3.68E-59"},0.0128649268105119,123.594807680899,"Down"]
[25,"WP_PEPTIDE_GPCRS",-16.2790237492612,-0.0452646122996185,{"v":2.26149794066993e-57,"d":"2.26E-57"},{"v":5.26462071208587e-59,"d":"5.26E-59"},0.439660937982302,123.238757564808,"Down"]
[26,"REACTOME_ACETYLCHOLINE_BINDING_AND_DOWNSTREAM_EVENTS",-16.2625220435408,-0.0553089875495477,{"v":2.86229127154894e-57,"d":"2.86E-57"},{"v":6.85636573144314e-59,"d":"6.86E-59"},0.418593785332977,122.976127186507,"Down"]
[27,"BIOCARTA_BBCELL_PATHWAY",-15.8034488454582,-0.11775429658081,{"v":3.47800926488567e-54,"d":"3.48E-54"},{"v":9.6220229325447e-56,"d":"9.62E-56"},0.13913983818903,115.772477206259,"Down"]
[28,"WP_PATHOGENESIS_OF_SARSCOV2_MEDIATED_BY_NSP9NSP10_COMPLEX",-15.7599322777618,-0.0663998468718868,{"v":6.67927958713616e-54,"d":"6.68E-54"},{"v":1.89291324331794e-55,"d":"1.89E-55"},0.340541198986116,115.099924336304,"Down"]
[29,"REACTOME_DISEASES_OF_DNA_REPAIR",-15.5497166659178,-0.0824149429387631,{"v":1.61542998863104e-52,"d":"1.62E-52"},{"v":4.85065010081522e-54,"d":"4.85E-54"},-0.0992767912752308,111.876176683371,"Down"]
[30,"REACTOME_PHENYLALANINE_METABOLISM",-15.545123707631,-0.144108970289921,{"v":1.71400307203856e-52,"d":"1.71E-52"},{"v":5.20446276934784e-54,"d":"5.20E-54"},0.0795590698430086,111.80620726401,"Down"]
[31,"REACTOME_ACTIVATED_PKN1_STIMULATES_TRANSCRIPTION_OF_AR_ANDROGEN_RECEPTOR_REGULATED_GENES_KLK2_AND_KLK3",-15.471892466552,-0.140894416270361,{"v":5.19465767572775e-52,"d":"5.19E-52"},{"v":1.59485104079361e-53,"d":"1.59E-53"},-0.125894796813106,110.693289195205,"Down"]
[32,"REACTOME_RESOLUTION_OF_D_LOOP_STRUCTURES_THROUGH_SYNTHESIS_DEPENDENT_STRAND_ANNEALING_SDSA",-15.3058005607907,-0.0861805899140341,{"v":6.12688969499172e-51,"d":"6.13E-51"},{"v":1.98441771497708e-52,"d":"1.98E-52"},-0.0295554114449615,108.187920385856,"Down"]
[33,"BIOCARTA_TCYTOTOXIC_PATHWAY",-15.3005220556867,-0.0632594199630418,{"v":6.43410010510228e-51,"d":"6.43E-51"},{"v":2.14904153308072e-52,"d":"2.15E-52"},0.499368318110916,108.108725852521,"Down"]
[34,"WP_CILIOPATHIES",-14.9695633193866,-0.054098163896828,{"v":7.98390355050389e-49,"d":"7.98E-49"},{"v":3.01685964121605e-50,"d":"3.02E-50"},-0.0683650315928751,103.195953532948,"Down"]
[35,"REACTOME_HOMOLOGOUS_DNA_PAIRING_AND_STRAND_EXCHANGE",-14.7255284598756,-0.0732116572993429,{"v":2.60646678131431e-47,"d":"2.61E-47"},{"v":1.08163095175999e-48,"d":"1.08E-48"},-0.113490518130521,99.6399893457189,"Down"]
[36,"WP_EV_RELEASE_FROM_CARDIAC_CELLS_AND_THEIR_FUNCTIONAL_EFFECTS",-14.6586286093945,-0.084800973839497,{"v":6.71280464758336e-47,"d":"6.71E-47"},{"v":2.85732999802016e-48,"d":"2.86E-48"},0.112437257837516,98.6750286941769,"Down"]
[37,"KEGG_GLYCOSAMINOGLYCAN_BIOSYNTHESIS_HEPARAN_SULFATE",-14.6332608970164,-0.0892307952820397,{"v":9.5525644087841e-47,"d":"9.55E-47"},{"v":4.12526398220096e-48,"d":"4.13E-48"},-0.0629294040806316,98.3102376700661,"Down"]
[38,"REACTOME_FRUCTOSE_CATABOLISM",-14.3712017207149,-0.155639171569764,{"v":3.6397567396521e-45,"d":"3.64E-45"},{"v":1.76830286946661e-46,"d":"1.77E-46"},-0.0103832807436113,94.5775991720347,"Down"]
[39,"REACTOME_REGULATION_OF_SIGNALING_BY_NODAL",-14.0615819366106,-0.115938868261788,{"v":2.58585666400589e-43,"d":"2.59E-43"},{"v":1.37842561711515e-44,"d":"1.38E-44"},0.0472133198578839,90.2517849833876,"Down"]
[40,"REACTOME_LYSINE_CATABOLISM",-13.8746351714906,-0.0917991474573421,{"v":3.17231724344398e-42,"d":"3.17E-42"},{"v":1.83018302506384e-43,"d":"1.83E-43"},-0.0382707568339309,87.6841420694138,"Down"]
[41,"BIOCARTA_EOSINOPHILS_PATHWAY",-13.8473514209243,-0.101315213261659,{"v":4.58607195766015e-42,"d":"4.59E-42"},{"v":2.66193838178319e-43,"d":"2.66E-43"},0.162307905158212,87.3122000256073,"Down"]
[42,"REACTOME_GLI_PROTEINS_BIND_PROMOTERS_OF_HH_RESPONSIVE_GENES_TO_PROMOTE_TRANSCRIPTION",-13.653305161583,-0.138639775012266,{"v":6.0006068263258e-41,"d":"6.00E-41"},{"v":3.74531802587811e-42,"d":"3.75E-42"},0.0246901166372721,84.6874081899749,"Down"]
[43,"WP_HEDGEHOG_SIGNALING_PATHWAY_WP47",-13.6245284609528,-0.0921553109050709,{"v":8.75967621206839e-41,"d":"8.76E-41"},{"v":5.52651636861265e-42,"d":"5.53E-42"},-0.0274630268034175,84.3012212721754,"Down"]
[44,"BIOCARTA_IL17_PATHWAY",-13.4804126883908,-0.0618825929737976,{"v":5.70815338771629e-40,"d":"5.71E-40"},{"v":3.83239718001195e-41,"d":"3.83E-41"},0.367674101081623,82.3790882326622,"Down"]
[45,"REACTOME_PRESYNAPTIC_DEPOLARIZATION_AND_CALCIUM_CHANNEL_OPENING",-13.4402719005696,-0.0883751102817536,{"v":9.60983280530011e-40,"d":"9.61E-40"},{"v":6.54921129106148e-41,"d":"6.55E-41"},0.243696232155618,81.8472530326629,"Down"]
[46,"REACTOME_ADRENOCEPTORS",-13.3669954976213,-0.118917697067298,{"v":2.48427055617597e-39,"d":"2.48E-39"},{"v":1.73496627911075e-40,"d":"1.73E-40"},0.339863832141887,80.880375151809,"Down"]
[47,"WP_EICOSANOID_METABOLISM_VIA_CYTOCHROME_P450_MONOOXYGENASES_PATHWAY",-13.252047688655,-0.130205086026224,{"v":1.07140887768823e-38,"d":"1.07E-38"},{"v":7.91628016915395e-40,"d":"7.92E-40"},-0.0536185050357007,79.3740097253134,"Down"]
[48,"WP_KETONE_BODIES_SYNTHESIS_AND_DEGRADATION",-13.1641916730727,-0.136216137416984,{"v":3.2843796260402e-38,"d":"3.28E-38"},{"v":2.50428406034105e-39,"d":"2.50E-39"},-0.137687426162026,78.2312160918191,"Down"]
[49,"REACTOME_SURFACTANT_METABOLISM",-13.0699780632241,-0.059028461527451,{"v":1.10060308185242e-37,"d":"1.10E-37"},{"v":8.54044226808559e-39,"d":"8.54E-39"},0.177382016036997,77.0139520690192,"Down"]
[50,"REACTOME_ACTIVATION_OF_ATR_IN_RESPONSE_TO_REPLICATION_STRESS",-12.9392594728378,-0.0680451451441712,{"v":5.77757553438248e-37,"d":"5.78E-37"},{"v":4.61972132809935e-38,"d":"4.62E-38"},-0.0864187832667633,75.339144210082,"Down"]
[51,"REACTOME_HDR_THROUGH_MMEJ_ALT_NHEJ",-12.9267443339169,-0.0976841515959219,{"v":6.72844868337142e-37,"d":"6.73E-37"},{"v":5.42543601661865e-38,"d":"5.43E-38"},-0.145266170466855,75.1796569348369,"Down"]
[52,"REACTOME_PHENYLALANINE_AND_TYROSINE_METABOLISM",-12.7888519318651,-0.0936954113554196,{"v":3.820364486738e-36,"d":"3.82E-36"},{"v":3.15785863444943e-37,"d":"3.16E-37"},0.0724860776035548,73.4323814504373,"Down"]
[53,"REACTOME_METABOLISM_OF_PORPHYRINS",-12.7483395246252,-0.0713764430935563,{"v":6.28509418027448e-36,"d":"6.29E-36"},{"v":5.27998802593909e-37,"d":"5.28E-37"},-0.0781789536572584,72.9225099846148,"Down"]
[54,"BIOCARTA_EICOSANOID_PATHWAY",-12.7347535001981,-0.0591708680321857,{"v":7.40541249500637e-36,"d":"7.41E-36"},{"v":6.27111516952294e-37,"d":"6.27E-37"},0.213338148753528,72.7518755445807,"Down"]
[55,"REACTOME_RELEASE_OF_HH_NP_FROM_THE_SECRETING_CELL",-12.4807356048556,-0.134057338186243,{"v":1.68689373815838e-34,"d":"1.69E-34"},{"v":1.51387899578317e-35,"d":"1.51E-35"},0.109877198681974,69.5942213181714,"Down"]
[56,"WP_AFLATOXIN_B1_METABOLISM",-12.4802634646684,-0.114977777001994,{"v":1.69045334937054e-34,"d":"1.69E-34"},{"v":1.52277680257063e-35,"d":"1.52E-35"},0.0366887865490121,69.5884100486187,"Down"]
[57,"REACTOME_MEIOTIC_RECOMBINATION",-12.2162356846444,-0.0693736438840105,{"v":4.05859038581038e-33,"d":"4.06E-33"},{"v":3.90249075558691e-34,"d":"3.90E-34"},-0.134097661303913,66.3723046799772,"Down"]
[58,"REACTOME_FGFR2_LIGAND_BINDING_AND_ACTIVATION",-12.1411443433879,-0.0795300554748932,{"v":9.91199371962641e-33,"d":"9.91E-33"},{"v":9.69796956373704e-34,"d":"9.70E-34"},0.211095291387139,65.4698972191152,"Down"]
[59,"REACTOME_TRP_CHANNELS",-12.0977654906431,-0.0541305836435555,{"v":1.65013680131927e-32,"d":"1.65E-32"},{"v":1.63677536972964e-33,"d":"1.64E-33"},0.0857906137339233,64.9510724978435,"Down"]
[60,"WP_SMALL_LIGAND_GPCRS",-12.0962853445728,-0.0412343899660618,{"v":1.67412347905378e-32,"d":"1.67E-32"},{"v":1.66621601322829e-33,"d":"1.67E-33"},0.402138039275307,64.9334015222719,"Down"]
[61,"WP_GASTRIC_CANCER_NETWORK_1",-12.0333910663546,-0.0598405700416181,{"v":3.46979980459839e-32,"d":"3.47E-32"},{"v":3.54706255328378e-33,"d":"3.55E-33"},-0.0700750923180258,64.1844814087644,"Down"]
[62,"REACTOME_UBIQUINOL_BIOSYNTHESIS",-11.7118265465154,-0.0907623882352476,{"v":1.37915691518742e-30,"d":"1.38E-30"},{"v":1.59133490213933e-31,"d":"1.59E-31"},-0.185744277728507,60.4151231489799,"Down"]
[63,"KEGG_LINOLEIC_ACID_METABOLISM",-11.6708908056561,-0.053653516663894,{"v":2.20298068705954e-30,"d":"2.20E-30"},{"v":2.56419816813611e-31,"d":"2.56E-31"},0.212583869929438,59.9424489726472,"Down"]
[64,"REACTOME_ACTIVATION_OF_C3_AND_C5",-11.5973889861671,-0.0508248187134445,{"v":5.02183007404259e-30,"d":"5.02E-30"},{"v":6.01467502120486e-31,"d":"6.01E-31"},0.295105880242429,59.0978113460371,"Down"]
[65,"REACTOME_HISTIDINE_CATABOLISM",-11.581224866534,-0.0872339999773363,{"v":5.98575160712062e-30,"d":"5.99E-30"},{"v":7.24994880889441e-31,"d":"7.25E-31"},0.0650535157278206,58.912764442333,"Down"]
[66,"KEGG_PRIMARY_IMMUNODEFICIENCY",-11.5722618537095,-0.0496490143023168,{"v":6.61982003532807e-30,"d":"6.62E-30"},{"v":8.04026724938632e-31,"d":"8.04E-31"},0.199688559920436,58.8102648142213,"Down"]
[67,"WP_EDA_SIGNALING_IN_HAIR_FOLLICLE_DEVELOPMENT",-11.4970459216793,-0.066920880423624,{"v":1.51777329021467e-29,"d":"1.52E-29"},{"v":1.91001834429848e-30,"d":"1.91E-30"},0.0600387194339004,57.9531713324895,"Down"]
[68,"REACTOME_DIGESTION",-11.445470315989,-0.075461278419825,{"v":2.68094003258181e-29,"d":"2.68E-29"},{"v":3.44614761273168e-30,"d":"3.45E-30"},0.211529449730491,57.3686274448305,"Down"]
[69,"REACTOME_PD_1_SIGNALING",-11.4426061954709,-0.0500871743931143,{"v":2.76279633990256e-29,"d":"2.76E-29"},{"v":3.56068894009034e-30,"d":"3.56E-30"},0.198716301234724,57.3362417779637,"Down"]
[70,"REACTOME_TERMINAL_PATHWAY_OF_COMPLEMENT",-11.4174829106536,-0.0770159411435751,{"v":3.64114352142152e-29,"d":"3.64E-29"},{"v":4.74184007850441e-30,"d":"4.74E-30"},0.286733667189946,57.0525040318269,"Down"]
[71,"REACTOME_PI_3K_CASCADE_FGFR2",-11.3518642323385,-0.0710360331624866,{"v":7.49777399799292e-29,"d":"7.50E-29"},{"v":9.9919727706046e-30,"d":"9.99E-30"},-0.0207370233025402,56.3143027042107,"Down"]
[72,"BIOCARTA_STEM_PATHWAY",-11.3110027165927,-0.05441560776636,{"v":1.18116495940882e-28,"d":"1.18E-28"},{"v":1.58604471607528e-29,"d":"1.59E-29"},0.360287895653826,55.8567239409565,"Down"]
[73,"WP_ESTROGEN_METABOLISM",-11.2708737620508,-0.0649504955556654,{"v":1.81992797951505e-28,"d":"1.82E-28"},{"v":2.49288380459889e-29,"d":"2.49E-29"},0.155563238232741,55.4089234909799,"Down"]
[74,"REACTOME_ORGANIC_ANION_TRANSPORTERS",-11.2670849367047,-0.0661965115754687,{"v":1.89449337130936e-28,"d":"1.89E-28"},{"v":2.60141296262789e-29,"d":"2.60E-29"},0.269121317499886,55.3667244952446,"Down"]
[75,"WP_ATR_SIGNALING",-11.0644008695765,-0.0689187844981621,{"v":1.6861759969955e-27,"d":"1.69E-27"},{"v":2.49171756641036e-28,"d":"2.49E-28"},-0.136004947690213,53.1295699163884,"Down"]
[76,"REACTOME_ROLE_OF_SECOND_MESSENGERS_IN_NETRIN_1_SIGNALING",-10.92909811874,-0.0884914660450766,{"v":7.09751620944423e-27,"d":"7.10E-27"},{"v":1.10150386516341e-27,"d":"1.10E-27"},0.082159450132123,51.6583314713829,"Down"]
[77,"KEGG_BUTANOATE_METABOLISM",-10.9005907707093,-0.0595959454526125,{"v":9.56091654322397e-27,"d":"9.56E-27"},{"v":1.50316704087124e-27,"d":"1.50E-27"},-0.11771984972126,51.3506186115975,"Down"]
[78,"REACTOME_GAMMA_CARBOXYLATION_TRANSPORT_AND_AMINO_TERMINAL_CLEAVAGE_OF_PROTEINS",-10.8741347959619,-0.0845789586228591,{"v":1.25610147446287e-26,"d":"1.26E-26"},{"v":2.00450741370086e-27,"d":"2.00E-27"},-0.018651301906095,51.0657546893178,"Down"]
[79,"REACTOME_FGFR2C_LIGAND_BINDING_AND_ACTIVATION",-10.5755339894525,-0.0820499339123037,{"v":2.81326993815559e-25,"d":"2.81E-25"},{"v":4.92606983098093e-26,"d":"4.93E-26"},0.318921284308643,47.8977384267211,"Down"]
[80,"KEGG_TAURINE_AND_HYPOTAURINE_METABOLISM",-10.5418983228516,-0.0691041786115401,{"v":3.99020668462133e-25,"d":"3.99E-25"},{"v":7.02728707615497e-26,"d":"7.03E-26"},0.140989655436418,47.5463122959573,"Down"]
[81,"BIOCARTA_AHSP_PATHWAY",-10.368171245549,-0.0690801634514758,{"v":2.35286489095965e-24,"d":"2.35E-24"},{"v":4.32628665847845e-25,"d":"4.33E-25"},0.031901791504844,45.7487358475009,"Down"]
[82,"REACTOME_DIGESTION_AND_ABSORPTION",-10.3415161865456,-0.0591922793733153,{"v":3.07898093229371e-24,"d":"3.08E-24"},{"v":5.7029707551594e-25,"d":"5.70E-25"},0.240586085627584,45.4755322279335,"Down"]
[83,"BIOCARTA_NO2IL12_PATHWAY",-10.1899108023906,-0.0368589860581976,{"v":1.40886791825736e-23,"d":"1.41E-23"},{"v":2.70936138126414e-24,"d":"2.71E-24"},0.438621070097567,43.9347993522746,"Down"]
[84,"REACTOME_SYNTHESIS_OF_KETONE_BODIES",-10.1758891085267,-0.0875435301094864,{"v":1.61132186679351e-23,"d":"1.61E-23"},{"v":3.12587744064194e-24,"d":"3.13E-24"},-0.160723639516592,43.7934312290246,"Down"]
[85,"BIOCARTA_ION_PATHWAY",-10.1376400869113,-0.0850142050281207,{"v":2.36545782384343e-23,"d":"2.37E-23"},{"v":4.61280236903341e-24,"d":"4.61E-24"},-0.144150750227477,43.4087750188158,"Down"]
[86,"REACTOME_REMOVAL_OF_AMINOTERMINAL_PROPEPTIDES_FROM_GAMMA_CARBOXYLATED_PROTEINS",-10.0539134230399,-0.0817364523046157,{"v":5.33236261336193e-23,"d":"5.33E-23"},{"v":1.07582754480109e-23,"d":"1.08E-23"},0.0476010624007933,42.5717446970038,"Down"]
[87,"BIOCARTA_CSK_PATHWAY",-9.96441673506718,-0.0470651552502211,{"v":1.272363279549e-22,"d":"1.27E-22"},{"v":2.64002502335572e-23,"d":"2.64E-23"},0.110869944650927,41.6845890335006,"Down"]
[88,"WP_DRUG_INDUCTION_OF_BILE_ACID_PATHWAY",-9.94389365790276,-0.0590487387293793,{"v":1.55642826463716e-22,"d":"1.56E-22"},{"v":3.239933330908e-23,"d":"3.24E-23"},0.184001357029674,41.4822507145083,"Down"]
[89,"WP_OXIDATION_BY_CYTOCHROME_P450",-9.88666892444483,-0.03822725994879,{"v":2.69213924439285e-22,"d":"2.69E-22"},{"v":5.72215831298076e-23,"d":"5.72E-23"},0.020237240562972,40.9202388384121,"Down"]
[90,"WP_SULFATION_BIOTRANSFORMATION_REACTION",-9.86258731710205,-0.0667189588148429,{"v":3.37411269573152e-22,"d":"3.37E-22"},{"v":7.26276619391603e-23,"d":"7.26E-23"},0.0869141439569761,40.6846854136424,"Down"]
[91,"REACTOME_PHOSPHOLIPASE_C_MEDIATED_CASCADE_FGFR4",-9.80411378867352,-0.0496913708157346,{"v":5.85871728103996e-22,"d":"5.86E-22"},{"v":1.29271292233473e-22,"d":"1.29E-22"},0.38218756813281,40.1150843310567,"Down"]
[92,"REACTOME_BUTYROPHILIN_BTN_FAMILY_INTERACTIONS",-9.75872616513853,-0.0785311002862601,{"v":9.02065363009295e-22,"d":"9.02E-22"},{"v":2.01777778567869e-22,"d":"2.02E-22"},-0.124639889645587,39.675256295883,"Down"]
[93,"REACTOME_BIOSYNTHESIS_OF_MARESIN_LIKE_SPMS",-9.74278019266498,-0.030967510243834,{"v":1.04798937363782e-21,"d":"1.05E-21"},{"v":2.35832966334827e-22,"d":"2.36E-22"},0.406930633361813,39.5212095656538,"Down"]
[94,"REACTOME_FGFR3B_LIGAND_BINDING_AND_ACTIVATION",-9.52552867472098,-0.102596534436607,{"v":8.12185537242495e-21,"d":"8.12E-21"},{"v":1.92633749217771e-21,"d":"1.93E-21"},0.290345943537951,37.4471852643164,"Down"]
[95,"REACTOME_SPERM_MOTILITY_AND_TAXES",-9.29393738847052,-0.0408748607299325,{"v":6.88396232470064e-20,"d":"6.88E-20"},{"v":1.71866805677411e-20,"d":"1.72E-20"},0.447965214433595,35.2870658196865,"Down"]
[96,"WP_TAMOXIFEN_METABOLISM",-9.24101355383751,-0.0417578887858636,{"v":1.11035543937232e-19,"d":"1.11E-19"},{"v":2.81334998302501e-20,"d":"2.81E-20"},0.274394527828896,34.8007940896462,"Down"]
[97,"WP_CODEINE_AND_MORPHINE_METABOLISM",-9.17141946528144,-0.0450414001315296,{"v":2.04331037071137e-19,"d":"2.04E-19"},{"v":5.35645127544781e-20,"d":"5.36E-20"},0.307019363291021,34.1655258951843,"Down"]
[98,"REACTOME_SODIUM_PROTON_EXCHANGERS",-9.12913065789127,-0.0576457698111609,{"v":2.98414961451293e-19,"d":"2.98E-19"},{"v":7.90336520712771e-20,"d":"7.90E-20"},-0.00290428875154474,33.7818212510452,"Down"]
[99,"WP_EICOSANOID_METABOLISM_VIA_CYCLOOXYGENASES_COX",-9.12127605142689,-0.0467272199846838,{"v":3.2030392520645e-19,"d":"3.20E-19"},{"v":8.49388951458399e-20,"d":"8.49E-20"},0.0110638600694942,33.7107458076902,"Down"]
[100,"WP_MONOAMINE_GPCRS",-9.11111861247022,-0.0325435228393043,{"v":3.50218306085264e-19,"d":"3.50E-19"},{"v":9.32261280368668e-20,"d":"9.32E-20"},0.409169981821573,33.6189218616964,"Down"]
[101,"REACTOME_ACTIVATION_OF_THE_PRE_REPLICATIVE_COMPLEX",-9.06371401590716,-0.0500274657558881,{"v":5.36000263255985e-19,"d":"5.36E-19"},{"v":1.43765252796393e-19,"d":"1.44E-19"},-0.0985365549829125,33.1917170297775,"Down"]
[102,"KEGG_ARACHIDONIC_ACID_METABOLISM",-8.92992506736471,-0.0376235711037895,{"v":1.73335888749886e-18,"d":"1.73E-18"},{"v":4.82463253099379e-19,"d":"4.82E-19"},0.0314093716306354,31.997898148908,"Down"]
[103,"KEGG_TERPENOID_BACKBONE_BIOSYNTHESIS",-8.91318360792964,-0.0626556460544883,{"v":1.99989383981441e-18,"d":"2.00E-18"},{"v":5.60698981405458e-19,"d":"5.61E-19"},-0.15443698864902,31.8497460976946,"Down"]
[104,"REACTOME_TRAFFICKING_OF_AMPA_RECEPTORS",-8.91304117390877,-0.0401800897865243,{"v":2.00004332553303e-18,"d":"2.00E-18"},{"v":5.61415670325062e-19,"d":"5.61E-19"},-0.0393874833625753,31.848486818825,"Down"]
[105,"KEGG_ASTHMA",-8.89652383300993,-0.0390925808668557,{"v":2.30521989941272e-18,"d":"2.31E-18"},{"v":6.50967967546708e-19,"d":"6.51E-19"},0.318129493564498,31.7025895568192,"Down"]
[106,"REACTOME_N_GLYCAN_TRIMMING_AND_ELONGATION_IN_THE_CIS_GOLGI",-8.82454840232336,-0.0887612120123004,{"v":4.30773878931872e-18,"d":"4.31E-18"},{"v":1.23680354578618e-18,"d":"1.24E-18"},-0.182247564763903,31.0699536172846,"Down"]
[107,"BIOCARTA_ALTERNATIVE_PATHWAY",-8.81792512107622,-0.0543367851748403,{"v":4.56330809951582e-18,"d":"4.56E-18"},{"v":1.31172014196609e-18,"d":"1.31E-18"},0.101781353222443,31.0119927021924,"Down"]
[108,"WP_FARNESOID_X_RECEPTOR_PATHWAY",-8.81421432566671,-0.0654550920696977,{"v":4.71055105178737e-18,"d":"4.71E-18"},{"v":1.35563429391856e-18,"d":"1.36E-18"},0.126922572339461,30.9795380027193,"Down"]
[109,"REACTOME_HDR_THROUGH_SINGLE_STRAND_ANNEALING_SSA",-8.71306868959103,-0.0375917061536159,{"v":1.12096455504998e-17,"d":"1.12E-17"},{"v":3.30919023504972e-18,"d":"3.31E-18"},-0.18220950034976,30.1001153501044,"Down"]
[110,"REACTOME_MISMATCH_REPAIR",-8.70274593368576,-0.0577609603251505,{"v":1.21881344093815e-17,"d":"1.22E-17"},{"v":3.62272146243762e-18,"d":"3.62E-18"},-0.209288277489969,30.0109271154973,"Down"]
[111,"REACTOME_HEME_DEGRADATION",-8.70032044782644,-0.0699138700091058,{"v":1.24358440866728e-17,"d":"1.24E-17"},{"v":3.70054469785609e-18,"d":"3.70E-18"},-0.0273801274551835,29.9899861692041,"Down"]
[112,"WP_MAJOR_RECEPTORS_TARGETED_BY_EPINEPHRINE_AND_NOREPINEPHRINE",-8.64691660292697,-0.0472064351798513,{"v":1.96501273213952e-17,"d":"1.97E-17"},{"v":5.90034187450801e-18,"d":"5.90E-18"},0.228478386239301,29.5303749706872,"Down"]
[113,"REACTOME_AMINE_LIGAND_BINDING_RECEPTORS",-8.62755069479037,-0.0295575188327198,{"v":2.3188429170529e-17,"d":"2.32E-17"},{"v":6.98318357470225e-18,"d":"6.98E-18"},0.427853936763903,29.3643967511468,"Down"]
[114,"BIOCARTA_DC_PATHWAY",-8.58750958038364,-0.0319787214910647,{"v":3.26177402431066e-17,"d":"3.26E-17"},{"v":9.88216286717603e-18,"d":"9.88E-18"},0.496127348211534,29.0223856755789,"Down"]
[115,"REACTOME_ACTIVATION_OF_SMO",-8.41789486694079,-0.058605348324544,{"v":1.33460814035307e-16,"d":"1.33E-16"},{"v":4.22806020172583e-17,"d":"4.23E-17"},-0.122970720630178,27.591071618452,"Down"]
[116,"REACTOME_PHASE_I_FUNCTIONALIZATION_OF_COMPOUNDS",-8.41033940046064,-0.0240532030729131,{"v":1.41842697022635e-16,"d":"1.42E-16"},{"v":4.50795616043597e-17,"d":"4.51E-17"},-0.0607597721839194,27.5279709460698,"Down"]
[117,"REACTOME_E2F_ENABLED_INHIBITION_OF_PRE_REPLICATION_COMPLEX_FORMATION",-8.40179476762622,-0.0573821325545667,{"v":1.52012825496338e-16,"d":"1.52E-16"},{"v":4.84656275620917e-17,"d":"4.85E-17"},-0.0255238336669464,27.4566766348585,"Down"]
[118,"REACTOME_PI_3K_CASCADE_FGFR3",-8.35421193963669,-0.0544138725899055,{"v":2.23685463407258e-16,"d":"2.24E-16"},{"v":7.24487330873711e-17,"d":"7.24E-17"},-0.0514816082573041,27.0609685414902,"Down"]
[119,"WP_OXYSTEROLS_DERIVED_FROM_CHOLESTEROL",-8.25370856625414,-0.0354660715562385,{"v":5.05445196121209e-16,"d":"5.05E-16"},{"v":1.68140675902669e-16,"d":"1.68E-16"},-0.00159443433374018,26.2324718626298,"Down"]
[120,"REACTOME_SYNTHESIS_OF_WYBUTOSINE_AT_G37_OF_TRNA_PHE",-8.216030379619,-0.0702837489191084,{"v":6.84338875547463e-16,"d":"6.84E-16"},{"v":2.29960027005828e-16,"d":"2.30E-16"},-0.132936439729804,25.9244302514216,"Down"]
[121,"REACTOME_DEFECTIVE_FACTOR_IX_CAUSES_HEMOPHILIA_B",-8.1769484931126,-0.0710132712197118,{"v":9.38950239248005e-16,"d":"9.39E-16"},{"v":3.17735185548498e-16,"d":"3.18E-16"},0.0421857162119155,25.6063864759145,"Down"]
[122,"WP_HEDGEHOG_SIGNALING_PATHWAY_WP4249",-8.14408899069404,-0.0368485368735827,{"v":1.22230882257269e-15,"d":"1.22E-15"},{"v":4.16508741834823e-16,"d":"4.17E-16"},-0.182554349973911,25.3401413408761,"Down"]
[123,"REACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY",-8.07674097858547,-0.0323858949810618,{"v":2.08464345033443e-15,"d":"2.08E-15"},{"v":7.2301399019696e-16,"d":"7.23E-16"},-0.13906296563506,24.7977688121223,"Down"]
[124,"REACTOME_ZINC_EFFLUX_AND_COMPARTMENTALIZATION_BY_THE_SLC30_FAMILY",-8.05522162012871,-0.0632625326479017,{"v":2.47203569658975e-15,"d":"2.47E-15"},{"v":8.61542805187994e-16,"d":"8.62E-16"},-0.00131216647684797,24.625407365631,"Down"]
[125,"WP_BIOTIN_METABOLISM_INCLUDING_IEMS",-8.02940979568503,-0.053623163048917,{"v":3.0252589805179e-15,"d":"3.03E-15"},{"v":1.06251504680133e-15,"d":"1.06E-15"},-0.155001030982073,24.4192655916272,"Down"]
[126,"REACTOME_FGFR1C_LIGAND_BINDING_AND_ACTIVATION",-7.94555128285211,-0.0361907206511112,{"v":5.81779078894475e-15,"d":"5.82E-15"},{"v":2.09040053651355e-15,"d":"2.09E-15"},0.350687629281562,23.7540657464552,"Down"]
[127,"WP_ALANINE_AND_ASPARTATE_METABOLISM",-7.90295030579318,-0.0583535168071298,{"v":8.07702827701092e-15,"d":"8.08E-15"},{"v":2.94032169733292e-15,"d":"2.94E-15"},0.0383238131482951,23.4187868496139,"Down"]
[128,"WP_MALE_INFERTILITY",-7.90148471618139,-0.0211255425561842,{"v":8.16456338314572e-15,"d":"8.16E-15"},{"v":2.97494212341342e-15,"d":"2.97E-15"},-0.103351487128919,23.4072841086747,"Down"]
[129,"REACTOME_PHOSPHOLIPASE_C_MEDIATED_CASCADE_FGFR2",-7.87847240166409,-0.0505338897562392,{"v":9.73714350484972e-15,"d":"9.74E-15"},{"v":3.57422811514052e-15,"d":"3.57E-15"},0.24937736722435,23.2269480864187,"Down"]
[130,"REACTOME_PI_3K_CASCADE_FGFR4",-7.86622184788785,-0.0475104693180365,{"v":1.06753508913879e-14,"d":"1.07E-14"},{"v":3.94022735329904e-15,"d":"3.94E-15"},0.0292614037460523,23.131159116531,"Down"]
[131,"BIOCARTA_ASBCELL_PATHWAY",-7.86260691841954,-0.0525167468485668,{"v":1.09665583521304e-14,"d":"1.10E-14"},{"v":4.05511064572704e-15,"d":"4.06E-15"},0.208592896144786,23.1029216396574,"Down"]
[132,"KEGG_HEDGEHOG_SIGNALING_PATHWAY",-7.77296587515531,-0.0332429337228443,{"v":2.18952968211372e-14,"d":"2.19E-14"},{"v":8.23659107812686e-15,"d":"8.24E-15"},-0.0827051479713174,22.4068171004222,"Down"]
[133,"BIOCARTA_IL5_PATHWAY",-7.74205191743149,-0.0461427732080908,{"v":2.76332197086898e-14,"d":"2.76E-14"},{"v":1.04976401457438e-14,"d":"1.05E-14"},0.223242476748875,22.1685896893728,"Down"]
[134,"REACTOME_DISEASES_OF_BASE_EXCISION_REPAIR",-7.69279157377334,-0.0582063843387066,{"v":4.03431238491687e-14,"d":"4.03E-14"},{"v":1.54213088127895e-14,"d":"1.54E-14"},-0.107407460860859,21.7909262040431,"Down"]
[135,"REACTOME_REPRODUCTION",-7.66489311241211,-0.0267394273871859,{"v":4.98884464518945e-14,"d":"4.99E-14"},{"v":1.91542011006262e-14,"d":"1.92E-14"},-0.0643320872843848,21.5780971237466,"Down"]
[136,"REACTOME_SEROTONIN_NEUROTRANSMITTER_RELEASE_CYCLE",-7.61250841114396,-0.04055352552411,{"v":7.40165286436632e-14,"d":"7.40E-14"},{"v":2.87176140149166e-14,"d":"2.87E-14"},0.102824035331223,21.1805402781316,"Down"]
[137,"WP_GLUTATHIONE_METABOLISM",-7.6012241360276,-0.0445542376973106,{"v":8.03860335816105e-14,"d":"8.04E-14"},{"v":3.13245171345345e-14,"d":"3.13E-14"},-0.124344685677779,21.0952556472126,"Down"]
[138,"REACTOME_PHOSPHATE_BOND_HYDROLYSIS_BY_NTPDASE_PROTEINS",-7.45870440117657,-0.0479089897114753,{"v":2.29958885392691e-13,"d":"2.30E-13"},{"v":9.28680114085869e-14,"d":"9.29E-14"},0.0974334612074148,20.0289111025828,"Down"]
[139,"REACTOME_CDC6_ASSOCIATION_WITH_THE_ORC_ORIGIN_COMPLEX",-7.41409785838264,-0.0465906338413491,{"v":3.19153994846457e-13,"d":"3.19E-13"},{"v":1.29965881167231e-13,"d":"1.30E-13"},-0.0111215283235945,19.6992729776092,"Down"]
[140,"BIOCARTA_AMAN_PATHWAY",-7.29647979788679,-0.0384470249448773,{"v":7.45482163724335e-13,"d":"7.45E-13"},{"v":3.12378153625379e-13,"d":"3.12E-13"},0.202565177962621,18.8394889598347,"Down"]
[141,"WP_TRYPTOPHAN_METABOLISM",-7.28334160114899,-0.0347224458654135,{"v":8.18880547221797e-13,"d":"8.19E-13"},{"v":3.44239258380013e-13,"d":"3.44E-13"},-0.0279333579582729,18.7442958849067,"Down"]
[142,"REACTOME_METABOLISM_OF_INGESTED_SEMET_SEC_MESEC_INTO_H2SE",-7.28054973923484,-0.0636589744541545,{"v":8.35268199012487e-13,"d":"8.35E-13"},{"v":3.51410068882784e-13,"d":"3.51E-13"},0.0378156527870166,18.7240893152046,"Down"]
[143,"REACTOME_RRNA_MODIFICATION_IN_THE_MITOCHONDRION",-7.23572033630088,-0.0580890917621898,{"v":1.15172945298623e-12,"d":"1.15E-12"},{"v":4.88806410030487e-13,"d":"4.89E-13"},-0.204808379696087,18.4006813944811,"Down"]
[144,"REACTOME_FRUCTOSE_METABOLISM",-7.16656639630171,-0.0674680987396266,{"v":1.87453775829377e-12,"d":"1.87E-12"},{"v":8.1014941578081e-13,"d":"8.10E-13"},-0.113250274868564,17.9056779050369,"Down"]
[145,"REACTOME_POLO_LIKE_KINASE_MEDIATED_EVENTS",-7.07915822513746,-0.0431349569457946,{"v":3.46442138479782e-12,"d":"3.46E-12"},{"v":1.52415839601092e-12,"d":"1.52E-12"},-0.0198222996470364,17.2867593443149,"Down"]
[146,"REACTOME_FGFRL1_MODULATION_OF_FGFR1_SIGNALING",-7.07423904366615,-0.0435733581729412,{"v":3.58356933487129e-12,"d":"3.58E-12"},{"v":1.57899512528405e-12,"d":"1.58E-12"},0.262749982716607,17.2521516866248,"Down"]
[147,"REACTOME_ABC_TRANSPORTERS_IN_LIPID_HOMEOSTASIS",-7.00584127447325,-0.0363617248066783,{"v":5.74704409981068e-12,"d":"5.75E-12"},{"v":2.57492394215539e-12,"d":"2.57E-12"},0.119777617069876,16.7734303236192,"Down"]
[148,"WP_GPCRS_CLASS_A_RHODOPSINLIKE",-6.96630167013734,-0.0167176936550744,{"v":7.52949858317604e-12,"d":"7.53E-12"},{"v":3.40910495904934e-12,"d":"3.41E-12"},0.374394262716454,16.4987951645788,"Down"]
[149,"REACTOME_PKA_MEDIATED_PHOSPHORYLATION_OF_KEY_METABOLIC_FACTORS",-6.95093106531511,-0.0546926147312415,{"v":8.34420449741683e-12,"d":"8.34E-12"},{"v":3.8004979998356e-12,"d":"3.80E-12"},0.0563710953289343,16.392450106051,"Down"]
[150,"REACTOME_ALPHA_DEFENSINS",-6.94645905535623,-0.111168282179436,{"v":8.60552422192126e-12,"d":"8.61E-12"},{"v":3.92242348981634e-12,"d":"3.92E-12"},0.000772024114806621,16.3615532675049,"Down"]
[151,"WP_EICOSANOID_METABOLISM_VIA_LIPOOXYGENASES_LOX",-6.88279427520564,-0.0360319595957918,{"v":1.32363364961437e-11,"d":"1.32E-11"},{"v":6.13587258626903e-12,"d":"6.14E-12"},-0.0947769851891067,15.9238381011882,"Down"]
[152,"WP_BENZENE_METABOLISM",-6.85346520899222,-0.0550514695611143,{"v":1.61328971545518e-11,"d":"1.61E-11"},{"v":7.53046436645386e-12,"d":"7.53E-12"},0.00969079540605691,15.7235378187017,"Down"]
[153,"WP_VITAMIN_B6DEPENDENT_AND_RESPONSIVE_DISORDERS",-6.74776983258465,-0.0733187694250252,{"v":3.29797428570052e-11,"d":"3.30E-11"},{"v":1.56442369962717e-11,"d":"1.56E-11"},-0.161189546629949,15.0087459371518,"Down"]
[154,"REACTOME_LTC4_CYSLTR_MEDIATED_IL4_PRODUCTION",-6.69641600594553,-0.0248155726760299,{"v":4.62702737539109e-11,"d":"4.63E-11"},{"v":2.22297131665213e-11,"d":"2.22E-11"},0.363342094611336,14.6654348833667,"Down"]
[155,"REACTOME_ARACHIDONATE_PRODUCTION_FROM_DAG",-6.64259732221793,-0.065282633360044,{"v":6.60793904704331e-11,"d":"6.61E-11"},{"v":3.20364656228112e-11,"d":"3.20E-11"},-0.161237594224045,14.3084411932846,"Down"]
[156,"REACTOME_CYTOSOLIC_SULFONATION_OF_SMALL_MOLECULES",-6.56649880738756,-0.0311701165111144,{"v":1.08890881851217e-10,"d":"1.09E-10"},{"v":5.34535199370853e-11,"d":"5.35E-11"},0.0374618961712564,13.8085430265077,"Down"]
[157,"REACTOME_LGI_ADAM_INTERACTIONS",-6.55518237059076,-0.0211313792928519,{"v":1.16885672509554e-10,"d":"1.17E-10"},{"v":5.76541340111226e-11,"d":"5.77E-11"},0.41822331557861,13.7346930214853,"Down"]
[158,"REACTOME_BIOSYNTHESIS_OF_MARESINS",-6.52934262014597,-0.043963859086863,{"v":1.38292624563384e-10,"d":"1.38E-10"},{"v":6.84931082520403e-11,"d":"6.85E-11"},0.233016495252193,13.5665396145874,"Down"]
[159,"REACTOME_BETA_OXIDATION_OF_BUTANOYL_COA_TO_ACETYL_COA",-6.52550520887536,-0.0771708343835235,{"v":1.41675451303227e-10,"d":"1.42E-10"},{"v":7.02641408285234e-11,"d":"7.03E-11"},-0.110813207174384,13.5416237491296,"Down"]
[160,"REACTOME_DIGESTION_OF_DIETARY_CARBOHYDRATE",-6.5104248547046,-0.0486969625395017,{"v":1.55598029963932e-10,"d":"1.56E-10"},{"v":7.7668177883372e-11,"d":"7.77E-11"},0.499519273687238,13.4438497316871,"Down"]
[161,"WP_FOXA2_PATHWAY",-6.49110988644804,-0.0334451201208501,{"v":1.75716973431805e-10,"d":"1.76E-10"},{"v":8.82734728204983e-11,"d":"8.83E-11"},-0.10743630264429,13.3189487295438,"Down"]
[162,"REACTOME_DISEASES_OF_MISMATCH_REPAIR_MMR",-6.46831031866689,-0.0508979625542413,{"v":2.03733289532162e-10,"d":"2.04E-10"},{"v":1.02622739970148e-10,"d":"1.03E-10"},-0.291602500788313,13.1719889365208,"Down"]
[163,"REACTOME_SIGNALING_BY_RNF43_MUTANTS",-6.45975612068625,-0.0501216527105674,{"v":2.15261660809982e-10,"d":"2.15E-10"},{"v":1.08574960496263e-10,"d":"1.09E-10"},-0.062391296981158,13.1169834594212,"Down"]
[164,"REACTOME_FGFR2B_LIGAND_BINDING_AND_ACTIVATION",-6.45592070199018,-0.0492008606574801,{"v":2.20472699699709e-10,"d":"2.20E-10"},{"v":1.11352102378699e-10,"d":"1.11E-10"},0.0131245576722862,13.092344312761,"Down"]
[165,"REACTOME_GLUTAMATE_AND_GLUTAMINE_METABOLISM",-6.42270008702851,-0.0451186033058372,{"v":2.73127021583298e-10,"d":"2.73E-10"},{"v":1.38498621268454e-10,"d":"1.38E-10"},-0.0810782733480052,12.8795398982792,"Down"]
[166,"BIOCARTA_ATRBRCA_PATHWAY",-6.41290714581121,-0.030758427412393,{"v":2.90629723685165e-10,"d":"2.91E-10"},{"v":1.47668138957442e-10,"d":"1.48E-10"},-0.130245832110611,12.8170165346446,"Down"]
[167,"WP_SLEEP_REGULATION",-6.37627196558395,-0.0273335295109379,{"v":3.66900490023621e-10,"d":"3.67E-10"},{"v":1.87535169495879e-10,"d":"1.88E-10"},0.189134364835457,12.5839587572103,"Down"]
[168,"REACTOME_DEFECTIVE_FACTOR_VIII_CAUSES_HEMOPHILIA_A",-6.28840830704148,-0.0589518339650547,{"v":6.38150687804493e-10,"d":"6.38E-10"},{"v":3.30916871509955e-10,"d":"3.31E-10"},-0.0482205437339233,12.0304145960143,"Down"]
[169,"REACTOME_PHASE_0_RAPID_DEPOLARISATION",-6.28078009443687,-0.0187667509206116,{"v":6.68860844314696e-10,"d":"6.69E-10"},{"v":3.47518792255274e-10,"d":"3.48E-10"},0.301660649653978,11.9827167482062,"Down"]
[170,"REACTOME_DEFECTIVE_C1GALT1C1_CAUSES_TNPS",-6.2720102959754,-0.0405137617762214,{"v":7.05063821189763e-10,"d":"7.05E-10"},{"v":3.67611389964214e-10,"d":"3.68E-10"},0.0761923693839347,11.927951878756,"Down"]
[171,"REACTOME_PREGNENOLONE_BIOSYNTHESIS",-6.25756399723054,-0.0479424030260559,{"v":7.72533728430098e-10,"d":"7.73E-10"},{"v":4.03208393347288e-10,"d":"4.03E-10"},-0.0780233446230834,11.8379047456128,"Down"]
[172,"REACTOME_SYNTHESIS_OF_LIPOXINS_LX",-6.23911872910915,-0.0600620579142957,{"v":8.66244719420892e-10,"d":"8.66E-10"},{"v":4.5358023095183e-10,"d":"4.54E-10"},0.0474362350344801,11.7232311292171,"Down"]
[173,"REACTOME_ERYTHROCYTES_TAKE_UP_OXYGEN_AND_RELEASE_CARBON_DIOXIDE",-6.20491727669862,-0.0456625300154409,{"v":1.0690312717636e-09,"d":"1.07E-09"},{"v":5.63730053227565e-10,"d":"5.64E-10"},0.23199531793821,11.5114923243293,"Down"]
[174,"KEGG_OTHER_GLYCAN_DEGRADATION",-6.17333207937275,-0.0395310096249444,{"v":1.2954671747482e-09,"d":"1.30E-09"},{"v":6.88380836784218e-10,"d":"6.88E-10"},-0.184144697297887,11.3169782714329,"Down"]
[175,"KEGG_STEROID_HORMONE_BIOSYNTHESIS",-6.15141304665007,-0.0274486901033903,{"v":1.48067800925478e-09,"d":"1.48E-09"},{"v":7.90294403050289e-10,"d":"7.90E-10"},0.0413708234360363,11.1825723405088,"Down"]
[176,"REACTOME_BIOTIN_TRANSPORT_AND_METABOLISM",-6.07367904472182,-0.0428417472089864,{"v":2.37694653922399e-09,"d":"2.38E-09"},{"v":1.28470592302187e-09,"d":"1.28E-09"},-0.17851650899077,10.7097451271212,"Down"]
[177,"REACTOME_HDR_THROUGH_HOMOLOGOUS_RECOMBINATION_HRR",-6.06020044630547,-0.0231302808948244,{"v":2.57790318613534e-09,"d":"2.58E-09"},{"v":1.39679909478183e-09,"d":"1.40E-09"},-0.118452296609657,10.6283680395344,"Down"]
[178,"REACTOME_ALTERNATIVE_COMPLEMENT_ACTIVATION",-6.03138398088658,-0.0392581676470211,{"v":3.071371389261e-09,"d":"3.07E-09"},{"v":1.66935874092425e-09,"d":"1.67E-09"},0.123909343123884,10.4549915812305,"Down"]
[179,"REACTOME_G2_M_DNA_REPLICATION_CHECKPOINT",-6.01206887282118,-0.067982666189112,{"v":3.44890604999045e-09,"d":"3.45E-09"},{"v":1.88037522833487e-09,"d":"1.88E-09"},-0.062029511285529,10.3392407868405,"Down"]
[180,"REACTOME_NUCLEAR_PORE_COMPLEX_NPC_DISASSEMBLY",-5.95351064158243,-0.025537983902722,{"v":4.89442601079128e-09,"d":"4.89E-09"},{"v":2.69160404776983e-09,"d":"2.69E-09"},-0.290849116548554,9.99057209263821,"Down"]
[181,"WP_DNA_MISMATCH_REPAIR",-5.93533720624913,-0.035139311123284,{"v":5.45030120173462e-09,"d":"5.45E-09"},{"v":3.0064920596613e-09,"d":"3.01E-09"},-0.178195789532535,9.88305358198336,"Down"]
[182,"REACTOME_UNWINDING_OF_DNA",-5.92471343841612,-0.0458789573148001,{"v":5.79940312803579e-09,"d":"5.80E-09"},{"v":3.20688992133963e-09,"d":"3.21E-09"},-0.0840051655541994,9.8203521849548,"Down"]
[183,"REACTOME_NEUROTRANSMITTER_RELEASE_CYCLE",-5.90839748452905,-0.0233857786115065,{"v":6.37498631157817e-09,"d":"6.37E-09"},{"v":3.54022519192229e-09,"d":"3.54E-09"},0.00800639034289419,9.724273115447,"Down"]
[184,"WP_NAD_METABOLISM_SIRTUINS_AND_AGING",-5.90537654205735,-0.0458541584617163,{"v":6.48865881732532e-09,"d":"6.49E-09"},{"v":3.60554017278502e-09,"d":"3.61E-09"},-0.251017089312228,9.70651273418887,"Down"]
[185,"BIOCARTA_AMI_PATHWAY",-5.90411578057768,-0.0308280680730877,{"v":6.53436892510485e-09,"d":"6.53E-09"},{"v":3.63314439560486e-09,"d":"3.63E-09"},0.159198373179648,9.69910328086556,"Down"]
[186,"REACTOME_THE_RETINOID_CYCLE_IN_CONES_DAYLIGHT_VISION",-5.89502924321465,-0.115987481059507,{"v":6.89910804392537e-09,"d":"6.90E-09"},{"v":3.83826894886401e-09,"d":"3.84E-09"},-0.283847888910062,9.64574854380441,"Down"]
[187,"REACTOME_DEFECTIVE_CHST3_CAUSES_SEDCJD",-5.88442267848658,-0.0510044552988332,{"v":7.34180084813044e-09,"d":"7.34E-09"},{"v":4.09198886677176e-09,"d":"4.09E-09"},0.0620261081665268,9.58357183907333,"Down"]
[188,"REACTOME_P2Y_RECEPTORS",-5.84011132332906,-0.0357792462856771,{"v":9.49517184395741e-09,"d":"9.50E-09"},{"v":5.3402332874079e-09,"d":"5.34E-09"},0.149350434942253,9.32501908930789,"Down"]
[189,"REACTOME_SCAVENGING_OF_HEME_FROM_PLASMA",-5.79173472311271,-0.0251981192419833,{"v":1.25874724793826e-08,"d":"1.26E-08"},{"v":7.12610621471119e-09,"d":"7.13E-09"},0.339406239710657,9.04496595208116,"Down"]
[190,"KEGG_INTESTINAL_IMMUNE_NETWORK_FOR_IGA_PRODUCTION",-5.76392847608159,-0.0199745570107641,{"v":1.47809422079908e-08,"d":"1.48E-08"},{"v":8.40279609327413e-09,"d":"8.40E-09"},0.164228182730948,8.88504390562485,"Down"]
[191,"REACTOME_DEFECTIVE_CHST14_CAUSES_EDS_MUSCULOCONTRACTURAL_TYPE",-5.74767968307785,-0.0515501602992408,{"v":1.62214036657559e-08,"d":"1.62E-08"},{"v":9.2490459497731e-09,"d":"9.25E-09"},0.0518380205889084,8.79194670836336,"Down"]
[192,"WP_NONCLASSICAL_ROLE_OF_VITAMIN_D",-5.742308519914,-0.0294635025179787,{"v":1.67326222351798e-08,"d":"1.67E-08"},{"v":9.54658251444218e-09,"d":"9.55E-09"},0.266808619583874,8.76123022109405,"Down"]
[193,"REACTOME_SYNTHESIS_OF_PYROPHOSPHATES_IN_THE_CYTOSOL",-5.74221542317607,-0.0388609710695963,{"v":1.67326222351798e-08,"d":"1.67E-08"},{"v":9.55182079012287e-09,"d":"9.55E-09"},-0.136782527171333,8.76069807347951,"Down"]
[194,"BIOCARTA_BARD1_PATHWAY",-5.73275086690077,-0.045492937058911,{"v":1.76601962223247e-08,"d":"1.77E-08"},{"v":1.00992012809853e-08,"d":"1.01E-08"},-0.102472892261271,8.70664278974296,"Down"]
[195,"REACTOME_ASPARTATE_AND_ASPARAGINE_METABOLISM",-5.57932451359913,-0.0421699082860011,{"v":4.19212196384874e-08,"d":"4.19E-08"},{"v":2.46237663261156e-08,"d":"2.46E-08"},-0.0728007295320772,7.84275117371822,"Down"]
[196,"REACTOME_REGULATION_OF_GLUCOKINASE_BY_GLUCOKINASE_REGULATORY_PROTEIN",-5.54821911142475,-0.0248351102109562,{"v":4.99124988505525e-08,"d":"4.99E-08"},{"v":2.94187366706867e-08,"d":"2.94E-08"},-0.296656938454039,7.67045065017533,"Down"]
[197,"BIOCARTA_LEPTIN_PATHWAY",-5.54248005980088,-0.0330633464516298,{"v":5.14844796061091e-08,"d":"5.15E-08"},{"v":3.03973816837689e-08,"d":"3.04E-08"},-0.124619962676558,7.63876538748345,"Down"]
[198,"REACTOME_GENERATION_OF_SECOND_MESSENGER_MOLECULES",-5.45435485028599,-0.0225195754618346,{"v":8.36574568842518e-08,"d":"8.37E-08"},{"v":5.00420617597093e-08,"d":"5.00E-08"},0.0913621980348615,7.1563254828118,"Down"]
[199,"REACTOME_COMMON_PATHWAY_OF_FIBRIN_CLOT_FORMATION",-5.41951754049221,-0.0342116715870881,{"v":1.01043051401557e-07,"d":"1.01E-07"},{"v":6.08167353914905e-08,"d":"6.08E-08"},0.105580341441529,6.96773207125111,"Down"]
[200,"REACTOME_REGULATION_OF_FZD_BY_UBIQUITINATION",-5.33028425179606,-0.0366900779723304,{"v":1.63691943891159e-07,"d":"1.64E-07"},{"v":9.96841966003855e-08,"d":"9.97E-08"},-0.0457910598368297,6.49015091000464,"Down"]
[201,"KEGG_DRUG_METABOLISM_OTHER_ENZYMES",-5.30645179062743,-0.0233939760897883,{"v":1.8572006365074e-07,"d":"1.86E-07"},{"v":1.13600025438189e-07,"d":"1.14E-07"},-0.0768636076896788,6.36393410277339,"Down"]
[202,"REACTOME_BIOSYNTHESIS_OF_SPECIALIZED_PRORESOLVING_MEDIATORS_SPMS",-5.29163067950472,-0.0311145994876495,{"v":2.01054734961558e-07,"d":"2.01E-07"},{"v":1.23183332891427e-07,"d":"1.23E-07"},0.0293635099546113,6.28572545601401,"Down"]
[203,"REACTOME_AMPK_INHIBITS_CHREBP_TRANSCRIPTIONAL_ACTIVATION_ACTIVITY",-5.28907615186138,-0.0433950092312421,{"v":2.03652336213942e-07,"d":"2.04E-07"},{"v":1.24912262900454e-07,"d":"1.25E-07"},-0.188271900761996,6.27226762564286,"Down"]
[204,"REACTOME_TRANSCRIPTION_OF_E2F_TARGETS_UNDER_NEGATIVE_CONTROL_BY_P107_RBL1_AND_P130_RBL2_IN_COMPLEX_WITH_HDAC1",-5.25592253179053,-0.0336262685808463,{"v":2.43358715054834e-07,"d":"2.43E-07"},{"v":1.49594999605232e-07,"d":"1.50E-07"},-0.16910493738218,6.0981937953281,"Down"]
[205,"REACTOME_PROPIONYL_COA_CATABOLISM",-5.1814865316423,-0.052361582606185,{"v":3.60442150370877e-07,"d":"3.60E-07"},{"v":2.23391440698819e-07,"d":"2.23E-07"},-0.190278710810359,5.71133685827395,"Down"]
[206,"REACTOME_PP2A_MEDIATED_DEPHOSPHORYLATION_OF_KEY_METABOLIC_FACTORS",-5.16537854291499,-0.0482813465616029,{"v":3.91561870213898e-07,"d":"3.92E-07"},{"v":2.43471162889411e-07,"d":"2.43E-07"},-0.110808877516134,5.62834406410887,"Down"]
[207,"WP_ALTERNATIVE_PATHWAY_OF_FETAL_ANDROGEN_SYNTHESIS",-5.141398254939,-0.0456708827094475,{"v":4.43442868765462e-07,"d":"4.43E-07"},{"v":2.76628159361451e-07,"d":"2.77E-07"},-0.110116193438325,5.5052677722857,"Down"]
[208,"BIOCARTA_CIRCADIAN_PATHWAY",-5.08312139717927,-0.0475907352822266,{"v":5.97878141463212e-07,"d":"5.98E-07"},{"v":3.76396967601334e-07,"d":"3.76E-07"},-0.28316499506095,5.20854550341673,"Down"]
[209,"REACTOME_VLDL_ASSEMBLY",-5.07624373168661,-0.0707624478920459,{"v":6.1921084617688e-07,"d":"6.19E-07"},{"v":3.90244892259923e-07,"d":"3.90E-07"},0.0744683979401938,5.17374946952399,"Down"]
[210,"WP_CLASSICAL_PATHWAY_OF_STEROIDOGENESIS_WITH_GLUCOCORTICOID_AND_MINERALOCORTICOID_METABOLISM",-5.05674551398788,-0.0429854335415559,{"v":6.83632621381629e-07,"d":"6.84E-07"},{"v":4.32229261966657e-07,"d":"4.32E-07"},0.000163249433747807,5.07535763609336,"Down"]
[211,"KEGG_VALINE_LEUCINE_AND_ISOLEUCINE_DEGRADATION",-5.05484684579182,-0.0213675377458569,{"v":6.90087048228057e-07,"d":"6.90E-07"},{"v":4.36542920184752e-07,"d":"4.37E-07"},-0.140509388663285,5.06579673609216,"Down"]
[212,"REACTOME_DNA_STRAND_ELONGATION",-5.05445696934354,-0.0293037005385885,{"v":6.91126784179509e-07,"d":"6.91E-07"},{"v":4.37433821565708e-07,"d":"4.37E-07"},-0.143356689855519,5.06383392375097,"Down"]
[213,"REACTOME_SIGNALING_BY_NODAL",-5.01924844254269,-0.0306409861276381,{"v":8.28570554948147e-07,"d":"8.29E-07"},{"v":5.25544076687759e-07,"d":"5.26E-07"},-0.148959173182623,4.8872002219651,"Down"]
[214,"REACTOME_SYNTHESIS_OF_PIPS_AT_THE_LATE_ENDOSOME_MEMBRANE",-4.96392190612439,-0.0319730843363366,{"v":1.09412611256479e-06,"d":"1.09E-06"},{"v":6.99517200846925e-07,"d":"7.00E-07"},-0.237168250535281,4.61212374118888,"Down"]
[215,"REACTOME_TRAFFICKING_OF_MYRISTOYLATED_PROTEINS_TO_THE_CILIUM",-4.92995064340702,-0.0442882171931371,{"v":1.29743853729993e-06,"d":"1.30E-06"},{"v":8.32566834664124e-07,"d":"8.33E-07"},0.00492274076794569,4.44472807389633,"Down"]
[216,"KEGG_ASCORBATE_AND_ALDARATE_METABOLISM",-4.87193177560709,-0.0337045906688465,{"v":1.73138226571174e-06,"d":"1.73E-06"},{"v":1.11803834567216e-06,"d":"1.12E-06"},0.100310845803951,4.16148458327397,"Down"]
[217,"REACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS_VIA_24_HYDROXYCHOLESTEROL",-4.84057379022872,-0.032503133926741,{"v":2.01719061991802e-06,"d":"2.02E-06"},{"v":1.30940443749065e-06,"d":"1.31E-06"},-0.00228947632039057,4.00978824418017,"Down"]
[218,"REACTOME_PI_3K_CASCADE_FGFR1",-4.79247515428572,-0.0289076326398105,{"v":2.54975649181688e-06,"d":"2.55E-06"},{"v":1.66542799195596e-06,"d":"1.67E-06"},-0.00280044647875505,3.77900465965934,"Down"]
[219,"REACTOME_CRMPS_IN_SEMA3A_SIGNALING",-4.73025100444461,-0.026380567500346,{"v":3.43873522317906e-06,"d":"3.44E-06"},{"v":2.2658063059611e-06,"d":"2.27E-06"},-0.0897495245509192,3.48385237615992,"Down"]
[220,"REACTOME_WAX_AND_PLASMALOGEN_BIOSYNTHESIS",-4.72499882129447,-0.0360893231096603,{"v":3.52505113431181e-06,"d":"3.53E-06"},{"v":2.32505903089729e-06,"d":"2.33E-06"},-0.136755662527348,3.45911524167079,"Down"]
[221,"REACTOME_FRS_MEDIATED_FGFR2_SIGNALING",-4.71616450766718,-0.0263326726417268,{"v":3.67434319424205e-06,"d":"3.67E-06"},{"v":2.42809466783426e-06,"d":"2.43E-06"},-0.0898266967516973,3.41756849245492,"Down"]
[222,"KEGG_ABC_TRANSPORTERS",-4.69496638739338,-0.0181287678699599,{"v":4.06082846687405e-06,"d":"4.06E-06"},{"v":2.69351847701565e-06,"d":"2.69E-06"},0.111005923906324,3.31819224862408,"Down"]
[223,"KEGG_SULFUR_METABOLISM",-4.64331412788715,-0.0295431794111251,{"v":5.17195381653951e-06,"d":"5.17E-06"},{"v":3.46192860054467e-06,"d":"3.46E-06"},0.0292238996864749,3.07791594144148,"Down"]
[224,"PID_P38_MKK3_6PATHWAY",-4.64017006539876,-0.0272316640952417,{"v":5.24585047037528e-06,"d":"5.25E-06"},{"v":3.51493219776158e-06,"d":"3.51E-06"},-0.215480241849722,3.06337590967697,"Down"]
[225,"REACTOME_GLYOXYLATE_METABOLISM_AND_GLYCINE_DEGRADATION",-4.62870399577721,-0.0225048005284119,{"v":5.52759571181583e-06,"d":"5.53E-06"},{"v":3.71490238122035e-06,"d":"3.71E-06"},-0.183560686434282,3.01043310016693,"Down"]
[226,"WP_DNA_REPLICATION",-4.62659717858123,-0.0236160896547324,{"v":5.58120276692491e-06,"d":"5.58E-06"},{"v":3.75281279166038e-06,"d":"3.75E-06"},-0.128584261885651,3.00071939489002,"Down"]
[227,"KEGG_MISMATCH_REPAIR",-4.62455295574254,-0.0271901826746542,{"v":5.63360855126612e-06,"d":"5.63E-06"},{"v":3.78995123185717e-06,"d":"3.79E-06"},-0.195474886039286,2.99129850096378,"Down"]
[228,"WP_RESISTIN_AS_A_REGULATOR_OF_INFLAMMATION",-4.58752052891106,-0.0213087506311284,{"v":6.70562648173251e-06,"d":"6.71E-06"},{"v":4.52697658230322e-06,"d":"4.53E-06"},-0.118060722026623,2.82135143083821,"Down"]
[229,"WP_FATTY_ACID_OMEGAOXIDATION",-4.56686993362341,-0.0290709472322691,{"v":7.37779701244935e-06,"d":"7.38E-06"},{"v":4.99569453575771e-06,"d":"5.00E-06"},0.180400278887177,2.72717441879977,"Down"]
[230,"BIOCARTA_FIBRINOLYSIS_PATHWAY",-4.56157015199414,-0.0416667398346309,{"v":7.55493045336946e-06,"d":"7.55E-06"},{"v":5.12328279732544e-06,"d":"5.12E-06"},-0.157906530898619,2.7030730683124,"Down"]
[231,"REACTOME_E2F_MEDIATED_REGULATION_OF_DNA_REPLICATION",-4.44127957337428,-0.025266083350541,{"v":1.31508848432731e-05,"d":"1.32E-05"},{"v":9.01572132305362e-06,"d":"9.02E-06"},-0.137545955436189,2.16354108461256,"Down"]
[232,"REACTOME_KINESINS",-4.40397365406723,-0.0189408822635904,{"v":1.55803189113128e-05,"d":"1.56E-05"},{"v":1.07127833809904e-05,"d":"1.07E-05"},0.00762669758570448,1.99913533164567,"Down"]
[233,"REACTOME_TRNA_MODIFICATION_IN_THE_NUCLEUS_AND_CYTOSOL",-4.37606390315936,-0.0193244205008658,{"v":1.76328106975318e-05,"d":"1.76E-05"},{"v":1.21775855255896e-05,"d":"1.22E-05"},-0.223283024765581,1.87704230596028,"Down"]
[234,"REACTOME_ENDOGENOUS_STEROLS",-4.36502444776874,-0.0212426108300182,{"v":1.84916915030809e-05,"d":"1.85E-05"},{"v":1.28081790336792e-05,"d":"1.28E-05"},-0.0738613614825692,1.82896309395918,"Down"]
[235,"PID_FANCONI_PATHWAY",-4.36212729723378,-0.0197934449743445,{"v":1.87197314995231e-05,"d":"1.87E-05"},{"v":1.29787612117139e-05,"d":"1.30E-05"},-0.189234341489587,1.81636543666965,"Down"]
[236,"REACTOME_TRANSPORT_OF_VITAMINS_NUCLEOSIDES_AND_RELATED_MOLECULES",-4.35895197933601,-0.0192454146561676,{"v":1.89837440149433e-05,"d":"1.90E-05"},{"v":1.31682110980848e-05,"d":"1.32E-05"},-0.0459273323030742,1.80256780573504,"Down"]
[237,"PID_HEDGEHOG_2PATHWAY",-4.35399664744782,-0.0271839249007645,{"v":1.93987083613583e-05,"d":"1.94E-05"},{"v":1.34691436598095e-05,"d":"1.35E-05"},-0.153048234074758,1.78105554003372,"Down"]
[238,"BIOCARTA_RHODOPSIN_PATHWAY",-4.31082288431667,-0.0275841706320042,{"v":2.34820150898356e-05,"d":"2.35E-05"},{"v":1.6383538193583e-05,"d":"1.64E-05"},0.372711200037074,1.59466039590848,"Down"]
[239,"REACTOME_FGFR3_LIGAND_BINDING_AND_ACTIVATION",-4.28996067012711,-0.0280981340962123,{"v":2.57593551088325e-05,"d":"2.58E-05"},{"v":1.79985237619406e-05,"d":"1.80E-05"},0.222473769844305,1.50525519993863,"Down"]
[240,"REACTOME_DOWNSTREAM_SIGNALING_OF_ACTIVATED_FGFR2",-4.25620871748345,-0.021782678300876,{"v":2.98206265959017e-05,"d":"2.98E-05"},{"v":2.0936816446043e-05,"d":"2.09E-05"},-0.140198078313067,1.36152683183333,"Down"]
[241,"REACTOME_TLR3_MEDIATED_TICAM1_DEPENDENT_PROGRAMMED_CELL_DEATH",-4.23948522654538,-0.0323621025017371,{"v":3.20970398483863e-05,"d":"3.21E-05"},{"v":2.25567253725333e-05,"d":"2.26E-05"},-0.185536495688611,1.29073143375447,"Down"]
[242,"WP_DISRUPTION_OF_POSTSYNAPTIC_SIGNALING_BY_CNV",-4.21990618705448,-0.0189065057425481,{"v":3.49275779051669e-05,"d":"3.49E-05"},{"v":2.46048524514131e-05,"d":"2.46E-05"},0.0377020917952552,1.20820086606347,"Down"]
[243,"REACTOME_LDL_REMODELING",-4.20923515516857,-0.0662745603010033,{"v":3.6528739522374e-05,"d":"3.65E-05"},{"v":2.57944169434308e-05,"d":"2.58E-05"},0.162301585881913,1.16338019861134,"Down"]
[244,"KEGG_AMINOACYL_TRNA_BIOSYNTHESIS",-4.15686702453215,-0.0237735308652493,{"v":4.57842906537918e-05,"d":"4.58E-05"},{"v":3.24691561923989e-05,"d":"3.25E-05"},-0.164174584140056,0.945063199227507,"Down"]
[245,"REACTOME_DEFECTIVE_CHSY1_CAUSES_TPBS",-4.11829971735895,-0.0340124961796479,{"v":5.38680033621403e-05,"d":"5.39E-05"},{"v":3.84018525992586e-05,"d":"3.84E-05"},0.00522871201502784,0.7860233559832,"Down"]
[246,"REACTOME_ANDROGEN_BIOSYNTHESIS",-4.10437648852091,-0.0359530806783178,{"v":5.71313676263627e-05,"d":"5.71E-05"},{"v":4.07860910584964e-05,"d":"4.08E-05"},-0.13991431769685,0.728971443673187,"Down"]
[247,"BIOCARTA_PLCD_PATHWAY",-4.10020888763658,-0.0380310191443352,{"v":5.81412311013629e-05,"d":"5.81E-05"},{"v":4.15266485295497e-05,"d":"4.15E-05"},-0.0586967895307804,0.711931730484778,"Down"]
[248,"WP_CHOLESTEROL_METABOLISM_WITH_BLOCH_AND_KANDUTSCHRUSSELL_PATHWAYS",-4.08748682869593,-0.0203895383404226,{"v":6.13310457768203e-05,"d":"6.13E-05"},{"v":4.3867009799885e-05,"d":"4.39E-05"},-0.201304566413456,0.660022939801737,"Down"]
[249,"BIOCARTA_SLRP_PATHWAY",-4.08699926456489,-0.0487849558132924,{"v":6.14308858904942e-05,"d":"6.14E-05"},{"v":4.39591460775095e-05,"d":"4.40E-05"},-0.0728684120578992,0.658036772564225,"Down"]
[250,"WP_TRYPTOPHAN_CATABOLISM_LEADING_TO_NAD_PRODUCTION",-4.07501061566854,-0.0230117899248777,{"v":6.45874016775725e-05,"d":"6.46E-05"},{"v":4.62832797446572e-05,"d":"4.63E-05"},0.0713145642179419,0.609273521587053,"Down"]
[251,"REACTOME_NR1H2_NR1H3_REGULATE_GENE_EXPRESSION_LINKED_TO_TRIGLYCERIDE_LIPOLYSIS_IN_ADIPOSE",-4.06686780062841,-0.0417795568934938,{"v":6.68193846153373e-05,"d":"6.68E-05"},{"v":4.79278042146448e-05,"d":"4.79E-05"},-0.0914647141017621,0.576234498478788,"Down"]
[252,"PID_HNF3B_PATHWAY",-4.05650960617924,-0.021762977192342,{"v":6.9781997227005e-05,"d":"6.98E-05"},{"v":5.00998954450293e-05,"d":"5.01E-05"},-0.0492573445033183,0.534301955700633,"Down"]
[253,"REACTOME_MOLYBDENUM_COFACTOR_BIOSYNTHESIS",-3.89607041713409,-0.0285723416127305,0.00013469843745124,{"v":9.82516942542447e-05,"d":"9.83E-05"},-0.00771657290685788,-0.101572762760404,"Down"]
[254,"REACTOME_BIOLOGICAL_OXIDATIONS",-3.88343958873786,-0.00891981791794985,0.000141820551965561,0.00010349455259835,-0.0518654729628499,-0.150546123640607,"Down"]
[255,"WP_MEVALONATE_ARM_OF_CHOLESTEROL_BIOSYNTHESIS_PATHWAY",-3.87501342602303,-0.0287727149417051,0.000146677309438949,0.000107137778318261,-0.249236611669616,-0.18312855725463,"Down"]
[256,"BIOCARTA_CTLA4_PATHWAY",-3.84785058766143,-0.019826656410977,0.000163379536828391,0.000119723466258861,0.0919449802245022,-0.287681591594687,"Down"]
[257,"REACTOME_TRANSCRIPTIONAL_REGULATION_OF_TESTIS_DIFFERENTIATION",-3.84228464490316,-0.0375735446990008,0.000166972386964831,0.000122468950493098,0.12176547731589,-0.309014988039254,"Down"]
[258,"KEGG_TASTE_TRANSDUCTION",-3.83273334499009,-0.0127458707769152,0.000173505184908112,0.00012731908811577,0.261037386920818,-0.345551837901007,"Down"]
[259,"WP_GENES_RELATED_TO_PRIMARY_CILIUM_DEVELOPMENT_BASED_ON_CRISPR",-3.81742997423272,-0.0130561844030165,0.000184188566182242,0.000135469323305428,-0.195925404006713,-0.403903089939305,"Down"]
[260,"REACTOME_FATTY_ACIDS_BOUND_TO_GPR40_FFAR1_REGULATE_INSULIN_SECRETION",-3.80252493166837,-0.0297793809344773,0.000195084378557641,0.000143878020083335,-0.0306879039734534,-0.460511612157848,"Down"]
[261,"WP_METAPATHWAY_BIOTRANSFORMATION_PHASE_I_AND_II",-3.69683114303739,-0.00929291534464685,0.00029411527854315,0.00021919725043921,0.0606884137577237,-0.855591261234185,"Down"]
[262,"REACTOME_GABA_SYNTHESIS_RELEASE_REUPTAKE_AND_DEGRADATION",-3.68639198938415,-0.0255559995316076,0.000306288773532006,0.000228373208335268,0.0492452986233885,-0.894009453087904,"Down"]
[263,"KEGG_TRYPTOPHAN_METABOLISM",-3.6730990006085,-0.0163875893706083,0.000322222747760847,0.000240579939539391,-0.000963693457700816,-0.942773411590334,"Down"]
[264,"PID_CIRCADIAN_PATHWAY",-3.66968683118866,-0.0251520088605271,0.000326254896330276,0.000243810592230621,-0.233900901963384,-0.955262249299831,"Down"]
[265,"KEGG_PORPHYRIN_AND_CHLOROPHYLL_METABOLISM",-3.623230818804,-0.0178122506106753,0.000389394133405719,0.000292045600054289,-0.0534996140493554,-1.12414288113726,"Down"]
[266,"BIOCARTA_INTRINSIC_PATHWAY",-3.60758237736061,-0.0218028215793206,0.000413059537738072,0.000310212729758754,0.0575205911239606,-1.18054589757651,"Down"]
[267,"WP_PHOSPHODIESTERASES_IN_NEURONAL_FUNCTION",-3.60603568847495,-0.0117011054118064,0.000415338931643398,0.000312064710111284,0.314903303434816,-1.18610752983856,"Down"]
[268,"WP_FLUOROPYRIMIDINE_ACTIVITY",-3.60400379812009,-0.0168911668518598,0.000418222392991902,0.000314513398778323,-0.162576989421008,-1.19341024733737,"Down"]
[269,"REACTOME_CHOLESTEROL_BIOSYNTHESIS",-3.5953465455308,-0.0229836608138203,0.000431784553261859,0.000325149501646582,-0.239490607187962,-1.22447881716705,"Down"]
[270,"BIOCARTA_MCM_PATHWAY",-3.58905699034625,-0.0215946552621355,0.000441929012523785,0.000333086846821234,-0.148531765076131,-1.24700358364569,"Down"]
[271,"WP_RIBOFLAVIN_AND_COQ_DISORDERS",-3.5578740111275,-0.0224912172977803,0.000496898369013955,0.000375188444619849,-0.248073421418644,-1.35809775811519,"Down"]
[272,"WP_PHOSPHOINOSITIDES_METABOLISM",-3.48430608447751,-0.013536422260215,0.00065211421168266,0.000495025970406878,-0.198918096555725,-1.61636065636399,"Down"]
[273,"BIOCARTA_ACETAMINOPHEN_PATHWAY",-3.46714077018292,-0.0298325609283507,0.000693017302629822,0.000527712568163127,0.17149897141216,-1.67584516949206,"Down"]
[274,"REACTOME_PROLACTIN_RECEPTOR_SIGNALING",-3.45824090164642,-0.0286467465937132,0.000715348665812844,0.000545441290397108,-0.22245119477115,-1.7065712560733,"Down"]
[275,"WP_GABA_METABOLISM_AKA_GHB",-3.44293745453564,-0.0427349367811634,0.000756035390552075,0.000577229449669145,-0.0721786782827065,-1.75922087556376,"Down"]
[276,"PID_ATR_PATHWAY",-3.43272861206955,-0.0157293969758324,0.000784361380423317,0.000599385467833608,-0.130873696263331,-1.79421353189071,"Down"]
[277,"REACTOME_POU5F1_OCT4_SOX2_NANOG_ACTIVATE_GENES_RELATED_TO_PROLIFERATION",-3.3888975788349,-0.0201782638244307,0.000917768607548362,0.000703808382239348,0.206353842191014,-1.94327362245911,"Down"]
[278,"REACTOME_POU5F1_OCT4_SOX2_NANOG_REPRESS_GENES_RELATED_TO_DIFFERENTIATION",-3.38065598861058,-0.0253631815540401,0.000943639974648264,0.000725240169449645,0.217958644083454,-1.97108795767031,"Down"]
[279,"REACTOME_TIGHT_JUNCTION_INTERACTIONS",-3.3740169601619,-0.018569188941207,0.000966250813279907,0.00074294386081812,-0.056868768229537,-1.9934446815019,"Down"]
[280,"WP_GAMMAGLUTAMYL_CYCLE_FOR_THE_BIOSYNTHESIS_AND_DEGRADATION_OF_GLUTATHIONE_INCLUDING_DISEASES",-3.35724175846009,-0.0355557501707254,0.00102542577589267,0.000789480978605627,-0.180142504266229,-2.04973918023541,"Down"]
[281,"REACTOME_ALPHA_OXIDATION_OF_PHYTANATE",-3.31307779701499,-0.0319359370021007,0.00119705125682177,0.000925251157010347,-0.1283922511798,-2.19660588200512,"Down"]
[282,"WP_SREBF_AND_MIR33_IN_CHOLESTEROL_AND_LIPID_HOMEOSTASIS",-3.2834100339441,-0.0225007790177302,0.00132744758416105,0.00102827923523406,-0.283648464323213,-2.29417544892116,"Down"]
[283,"REACTOME_DEFENSINS",-3.25397068625712,-0.0298960656397635,0.00147094141112034,0.00114092250477924,0.0397951482111526,-2.39012770860335,"Down"]
[284,"REACTOME_NUCLEAR_ENVELOPE_BREAKDOWN",-3.24273216477675,-0.0127062766289655,0.00152683924105513,0.00118685479466634,-0.270105622174537,-2.42653009302389,"Down"]
[285,"REACTOME_NICOTINAMIDE_SALVAGING",-3.19871421880915,-0.0180819785229474,0.00177314761707884,0.00138370122749776,-0.163108206356778,-2.56789666609339,"Down"]
[286,"BIOCARTA_LDL_PATHWAY",-3.15904835806647,-0.0277487853184032,0.00202682192354362,0.00158644630992618,0.0620262194918758,-2.69363382222317,"Down"]
[287,"REACTOME_BLOOD_GROUP_SYSTEMS_BIOSYNTHESIS",-3.15178708215867,-0.012555394544224,0.00207607537323071,0.00162639912842163,0.227085859177588,-2.71648176917264,"Down"]
[288,"REACTOME_DOPAMINE_NEUROTRANSMITTER_RELEASE_CYCLE",-3.13136638943818,-0.0154572177050141,0.00222207524049312,0.00174377429466498,-0.000321271759478221,-2.78045501892136,"Down"]
[289,"WP_LEPTIN_AND_ADIPONECTIN",-3.12802044011249,-0.0248631984103954,0.00224654255501276,0.00176373297082142,-0.218325925061332,-2.79089750489791,"Down"]
[290,"REACTOME_GLUTATHIONE_SYNTHESIS_AND_RECYCLING",-2.99164516062795,-0.021052273734551,0.00350329972564361,0.00277994634099655,-0.155433564685712,-3.20702870854413,"Down"]
[291,"WP_ONECARBON_METABOLISM_AND_RELATED_PATHWAYS",-2.97955366389926,-0.0114348797427707,0.00363983792183922,0.00289197648648156,-0.101576824655656,-3.24303045512916,"Down"]
[292,"REACTOME_MITOTIC_PROPHASE",-2.94621116269081,-0.0118542491816986,0.00404734854760903,0.00322258521334592,-0.23919488907964,-3.34155150638874,"Down"]
[293,"REACTOME_INSULIN_RECEPTOR_SIGNALLING_CASCADE",-2.93781503515381,-0.0114295491191042,0.00415147466912842,0.0033110951814506,-0.142841840436265,-3.36618603013958,"Down"]
[294,"REACTOME_DEFECTS_IN_COBALAMIN_B12_METABOLISM",-2.92378409420552,-0.0197511972988004,0.0043358019811512,0.00346396055714104,-0.160415949792356,-3.40719658453718,"Down"]
[295,"REACTOME_OTHER_SEMAPHORIN_INTERACTIONS",-2.89619245582613,-0.0142194364930676,0.00471777191883018,0.00378344934246267,0.0367136403980471,-3.48727131417495,"Down"]
[296,"REACTOME_DEFECTS_IN_VITAMIN_AND_COFACTOR_METABOLISM",-2.88675713725963,-0.0158797800583859,0.00485740000862667,0.00389870263850298,-0.182740436084522,-3.51447992067322,"Down"]
[297,"REACTOME_MITOCHONDRIAL_TRNA_AMINOACYLATION",-2.8805916882093,-0.0179572880887096,0.00494920475786283,0.0039757275737083,-0.147723415234953,-3.53221130946249,"Down"]
[298,"REACTOME_GLYCOSPHINGOLIPID_METABOLISM",-2.87770408919305,-0.0147366922706234,0.00499260457920775,0.0040122753399706,-0.119055644974826,-3.54050281775324,"Down"]
[299,"PID_THROMBIN_PAR4_PATHWAY",-2.85890570905672,-0.0204275495182549,0.00529139794485732,0.00425775441919187,-0.094822664781219,-3.59427782622992,"Down"]
[300,"WP_PEROXIREDOXIN_2_INDUCED_OVARIAN_FAILURE",-2.82433401229074,-0.0284426298487544,0.00588219157753676,0.00474504725434899,-0.184266090461744,-3.69225535180726,"Down"]
[301,"WP_FAMILIAL_HYPERLIPIDEMIA_TYPE_4",-2.80362741153901,-0.0158271223889761,0.00626544399366104,0.00506055091795699,0.0569252279115112,-3.75036856784433,"Down"]
[302,"REACTOME_NETRIN_MEDIATED_REPULSION_SIGNALS",-2.8002789147408,-0.0261819698057468,0.00632812981571077,0.00511331677079193,-0.00958147798039515,-3.75972602802477,"Down"]
[303,"REACTOME_HYDROLYSIS_OF_LPC",-2.79169513241261,-0.024472163539194,0.00649563768248373,0.00525085961107659,-0.115933001446945,-3.78366261263294,"Down"]
[304,"REACTOME_FLT3_SIGNALING_THROUGH_SRC_FAMILY_KINASES",-2.78422154786161,-0.0166856349389129,0.00663605730848918,0.00537332575586169,0.170512713617362,-3.8044435462517,"Down"]
[305,"REACTOME_ATF6_ATF6_ALPHA_ACTIVATES_CHAPERONE_GENES",-2.78299047952524,-0.0258350864030699,0.00665849988062935,0.00539374433650171,-0.222006713819437,-3.80786129832168,"Down"]
[306,"REACTOME_GLUTAMATE_NEUROTRANSMITTER_RELEASE_CYCLE",-2.77060799495816,-0.0147132460278497,0.00689677932361864,0.00560305148828397,-0.0243439500024411,-3.84215419403907,"Down"]
[307,"REACTOME_RSK_ACTIVATION",-2.71650702287678,-0.025668192498554,0.00809449161059956,0.00660613198584357,-0.284930132928828,-3.99019351456182,"Down"]
[308,"WP_SCFA_AND_SKELETAL_MUSCLE_SUBSTRATE_METABOLISM",-2.71149491370394,-0.0319575290208089,0.00821103070175554,0.00670678317440964,0.0341090431064154,-4.00376082748787,"Down"]
[309,"REACTOME_BETA_OXIDATION_OF_VERY_LONG_CHAIN_FATTY_ACIDS",-2.69314905815453,-0.0196481453499411,0.00866586203318759,0.0070870612579105,-0.191414779053398,-4.05320788829522,"Down"]
[310,"REACTOME_DISINHIBITION_OF_SNARE_FORMATION",-2.65634418335173,-0.0242575575146627,0.00964685108019377,0.00790885564266898,-0.167600142816691,-4.15139586706865,"Down"]
[311,"REACTOME_DEFECTIVE_GALNT3_CAUSES_HFTC",-2.64704361285059,-0.0181934220039978,0.009899800928912,0.00812959361031438,0.0849069034912655,-4.1759942971299,"Down"]
[312,"WP_ULTRACONSERVED_REGION_339_MODULATION_OF_TUMOR_SUPPRESSOR_MICRORNAS_IN_CANCER",-2.60640864911364,-0.0403530780980445,0.0111317972573324,0.00916007203462679,-0.241793696235411,-4.28245600816416,"Down"]
[313,"KEGG_PRIMARY_BILE_ACID_BIOSYNTHESIS",-2.60383529786147,-0.0174098594867938,0.0112110814032169,0.00922909535217586,0.00206633100656038,-4.28914267470569,"Down"]
[314,"BIOCARTA_SODD_PATHWAY",-2.57818073526459,-0.0191642218995282,0.0120437614324634,0.00994301087221254,-0.174773960216798,-4.35544340816105,"Down"]
[315,"REACTOME_NEGATIVE_REGULATION_OF_NMDA_RECEPTOR_MEDIATED_NEURONAL_TRANSMISSION",-2.50350387994238,-0.0108833842352074,0.0148369840163524,0.0123090903158605,0.139916044575864,-4.54470269322912,"Down"]
[316,"REACTOME_G0_AND_EARLY_G1",-2.50052454166072,-0.0124574007489963,0.0149562259420877,0.0124130620167124,-0.166229682462888,-4.55213818320982,"Down"]
[317,"REACTOME_METABOLISM_OF_STEROID_HORMONES",-2.48155216663165,-0.0117716509587919,0.0157505678494811,0.0130935894673149,-0.0293617113518194,-4.59927974148732,"Down"]
[318,"REACTOME_ROBO_RECEPTORS_BIND_AKAP5",-2.47841054381106,-0.0173145362550741,0.0158770005937831,0.013209407376609,-0.141818554728812,-4.60705126390561,"Down"]
[319,"KEGG_SELENOAMINO_ACID_METABOLISM",-2.47735256921599,-0.0122333915444851,0.0159176696107494,0.0132486136739942,-0.146009294908384,-4.60966619213358,"Down"]
[320,"REACTOME_PYRIMIDINE_SALVAGE",-2.4362627764162,-0.0211876482565867,0.0177877354803721,0.0148531192017277,-0.211202712307422,-4.71036226606839,"Down"]
[321,"REACTOME_THE_FATTY_ACID_CYCLING_MODEL",-2.40471678993823,-0.0112144892216364,0.0193679605754931,0.0161987767431334,0.120105883691433,-4.78652818323961,"Down"]
[322,"REACTOME_SEROTONIN_RECEPTORS",-2.39871521037729,-0.00925774025738857,0.0196643659298711,0.0164665844257558,0.579904795745671,-4.80090635078722,"Down"]
[323,"BIOCARTA_TNFR2_PATHWAY",-2.35267536095076,-0.0160178262119676,0.0222491950246113,0.0186535929946555,-0.219661766383858,-4.9100114525019,"Down"]
[324,"REACTOME_ACTIVATION_OF_AMPK_DOWNSTREAM_OF_NMDARS",-2.33484443284379,-0.0169004649444148,0.0232912782230449,0.0195665596408171,-0.0951862487579525,-4.95169959180572,"Down"]
[325,"BIOCARTA_CASPASE_PATHWAY",-2.32735107488329,-0.0132215552714068,0.0237521359923522,0.0199617310246118,-0.2033716857028,-4.96912425430538,"Down"]
[326,"REACTOME_CD22_MEDIATED_BCR_REGULATION",-2.32431734676407,-0.013270298162721,0.0239352386490365,0.020123689174561,0.230333686312762,-4.97616281134597,"Down"]
[327,"REACTOME_DECTIN_2_FAMILY",-2.3189092818302,-0.0141757053656824,0.0242722817398172,0.0204152491151701,0.133329933243649,-4.98868731884491,"Down"]
[328,"WP_PYRIMIDINE_METABOLISM_AND_RELATED_DISEASES",-2.31419517646387,-0.0135947618417207,0.0245583086494915,0.0206723954387588,-0.119269706376383,-4.99958090906138,"Down"]
[329,"REACTOME_DEPOLYMERISATION_OF_THE_NUCLEAR_LAMINA",-2.3080959720392,-0.0159912491782653,0.0249485251411688,0.0210092843294053,-0.189904768324357,-5.01364238713886,"Down"]
[330,"WP_MAMMALIAN_DISORDER_OF_SEXUAL_DEVELOPMENT",-2.27632671722722,-0.0135167394262929,0.0270604310074919,0.02284250957515,-0.0802807065471813,-5.08628560139194,"Down"]
[331,"REACTOME_CREB1_PHOSPHORYLATION_THROUGH_NMDA_RECEPTOR_MEDIATED_ACTIVATION_OF_RAS_SIGNALING",-2.23433113980333,-0.0106837885871723,0.0300505466274676,0.0254780781628968,-0.129258541448242,-5.1807683182118,"Down"]
[332,"REACTOME_PHASE_1_INACTIVATION_OF_FAST_NA_CHANNELS",-2.22870921149887,-0.0110769575512892,0.0304772561812144,0.0258501423885199,0.31163055655336,-5.19328325338998,"Down"]
[333,"REACTOME_FOXO_MEDIATED_TRANSCRIPTION_OF_CELL_DEATH_GENES",-2.20007209260735,-0.0144906463623569,0.0327076524760249,0.0278191605573748,-0.303149993653444,-5.2565431628881,"Down"]
[334,"REACTOME_SENSORY_PERCEPTION_OF_SALTY_TASTE",-2.1967024803528,-0.0230764426745637,0.0329767208762885,0.0280591396929823,-0.175375429596689,-5.26393294250584,"Down"]
[335,"REACTOME_ATF6_ATF6_ALPHA_ACTIVATES_CHAPERONES",-2.17832393321604,-0.018728467062394,0.034470196271875,0.0293996815706141,-0.224315813619956,-5.30403907590537,"Down"]
[336,"REACTOME_G1_S_SPECIFIC_TRANSCRIPTION",-2.17293189860322,-0.0104749551941879,0.0349019936029654,0.0298032880597522,-0.0771693335759402,-5.31574182653811,"Down"]
[337,"REACTOME_SYNTHESIS_OF_PROSTAGLANDINS_PG_AND_THROMBOXANES_TX",-2.16637066584312,-0.0147249040364246,0.0354706397058884,0.0303008298702124,-0.0695813457982302,-5.32994308725483,"Down"]
[338,"REACTOME_CARBOXYTERMINAL_POST_TRANSLATIONAL_MODIFICATIONS_OF_TUBULIN",-2.14840772124494,-0.0111811043759085,0.0370203819465863,0.0316996387923199,-0.049072074217713,-5.36860286083537,"Down"]
[339,"REACTOME_TRANSPORT_OF_NUCLEOTIDE_SUGARS",-2.13948656399022,-0.0137249212208772,0.0378256470533288,0.032414690794688,-0.211903328047601,-5.3876833922414,"Down"]
[340,"KEGG_RIBOFLAVIN_METABOLISM",-2.13036716496391,-0.012130854784189,0.0386647756062096,0.0331598716568775,-0.0611919982367839,-5.40710591767906,"Down"]
[341,"REACTOME_ACETYLCHOLINE_NEUROTRANSMITTER_RELEASE_CYCLE",-2.1156962886548,-0.0142004446887404,0.0400354756622264,0.0343894470431944,-0.0324150001295293,-5.4381780242078,"Down"]
[342,"REACTOME_DEFECTIVE_ST3GAL3_CAUSES_MCT12_AND_EIEE15",-2.11431697460196,-0.00620647199194507,0.0401442652678928,0.034507026672777,0.442960322405218,-5.4410883002331,"Down"]
[343,"WP_STATIN_INHIBITION_OF_CHOLESTEROL_PRODUCTION",-2.11241023609074,-0.0116007546147065,0.0403147396993287,0.0346701320828573,-0.0125407440918453,-5.44510828937975,"Down"]
[344,"KEGG_DNA_REPLICATION",-2.08148483228273,-0.0110987835107006,0.0434653033950574,0.0374089031581617,-0.162391530237623,-5.50980240004289,"Down"]
[345,"REACTOME_ACROSOME_REACTION_AND_SPERM_OOCYTE_MEMBRANE_BINDING",-2.07891589818548,-0.0244148919382979,0.0437218734981307,0.0376444740780126,0.164657549793501,-5.51513356675911,"Down"]
[346,"PID_IL8_CXCR2_PATHWAY",-2.04169439502785,-0.00983116975027522,0.0477039891723949,0.0412018260058472,-0.00622231358494164,-5.59163900540628,"Down"]
[347,"WP_DISORDERS_OF_FOLATE_METABOLISM_AND_TRANSPORT",-2.02174229914451,-0.0114900287844267,0.0499663493713123,0.0432232522901636,-0.0220739315126249,-5.63208008769537,"Down"]
[348,"KEGG_NEUROACTIVE_LIGAND_RECEPTOR_INTERACTION",-2.01619887113776,-0.00405119640483925,0.05061279848633,0.0437995371516318,0.314393107279808,-5.643245656801,"Down"]
[349,"REACTOME_STAT3_NUCLEAR_EVENTS_DOWNSTREAM_OF_ALK_SIGNALING",-2.00666762725162,-0.0172313369054812,0.0517148256639252,0.0448055574578137,-0.295502322247082,-5.66237185602632,"Down"]
[350,"REACTOME_HEME_BIOSYNTHESIS",-1.98694262594299,-0.0117357962597491,0.0541261796832859,0.0469495303528097,-0.170219868851857,-5.70166602738905,"NoSignifi"]
[351,"REACTOME_REACTIONS_SPECIFIC_TO_THE_COMPLEX_N_GLYCAN_SYNTHESIS_PATHWAY",-1.95605247331304,-0.0106263074882388,0.0579935024814247,0.0504801742247219,0.123000234506522,-5.762422847346,"NoSignifi"]
[352,"WP_ACETYLCHOLINE_SYNTHESIS",-1.95012065963226,-0.0181102087286003,0.0587099346109095,0.0511830199172031,-0.217661090336105,-5.77398104556596,"NoSignifi"]
[353,"REACTOME_RUNX1_REGULATES_EXPRESSION_OF_COMPONENTS_OF_TIGHT_JUNCTIONS",-1.93136105538314,-0.0188572653050803,0.061297977877982,0.0534599435946638,-0.1972821970312,-5.81030339714065,"NoSignifi"]
[354,"BIOCARTA_D4GDI_PATHWAY",-1.91567963069007,-0.0152385855525602,0.0634559439051176,0.0554276109211705,-0.157033053933633,-5.84039651915731,"NoSignifi"]
[355,"REACTOME_PASSIVE_TRANSPORT_BY_AQUAPORINS",-1.91094453859225,-0.0125078117275687,0.0641000651102001,0.0560334914644158,0.29066482631444,-5.84943510510489,"NoSignifi"]
[356,"REACTOME_SENSORY_PROCESSING_OF_SOUND_BY_OUTER_HAIR_CELLS_OF_THE_COCHLEA",-1.90267464043208,-0.00904828527956542,0.0652753237000741,0.0571048968806654,-0.0280588524384774,-5.86516748988328,"NoSignifi"]
[357,"WP_SEROTONIN_AND_ANXIETY",-1.89414288553298,-0.0131648692590079,0.066482237912167,0.0582280329352178,0.0245756413650927,-5.88132655503669,"NoSignifi"]
[358,"REACTOME_CATION_COUPLED_CHLORIDE_COTRANSPORTERS",-1.88102150437871,-0.0149793887653037,0.0684162060079768,0.0599911334057799,-0.0946329459434739,-5.90603667843807,"NoSignifi"]
[359,"REACTOME_PROCESSIVE_SYNTHESIS_ON_THE_LAGGING_STRAND",-1.85962297652275,-0.0124828784226146,0.0716931204507483,0.0629612660368751,-0.153915532518041,-5.94596600407417,"NoSignifi"]
[360,"BIOCARTA_ACE2_PATHWAY",-1.8404005679566,-0.0110359446820508,0.0747906907690215,0.0657320342285091,0.23834238850042,-5.98144541861367,"NoSignifi"]
[361,"KEGG_DRUG_METABOLISM_CYTOCHROME_P450",-1.81994534402174,-0.00705740994224521,0.0781502144450071,0.0687901179106017,0.0521686923643298,-6.01879561960444,"NoSignifi"]
[362,"REACTOME_TRANSCRIPTION_OF_E2F_TARGETS_UNDER_NEGATIVE_CONTROL_BY_DREAM_COMPLEX",-1.81062128410521,-0.0109265356837497,0.079716244930315,0.070222373654876,-0.218052914660767,-6.03568243852995,"NoSignifi"]
[363,"WP_HEMATOPOIETIC_STEM_CELL_GENE_REGULATION_BY_GABP_ALPHABETA_COMPLEX",-1.75036400934052,-0.0108059886752132,0.0905930864887127,0.0800789091094559,-0.27660300140354,-6.1427239339083,"NoSignifi"]
[364,"BIOCARTA_RAB_PATHWAY",-1.72598694667143,-0.0150683905513896,0.0952695300940132,0.0843733186561352,-0.230706781380197,-6.18499882095108,"NoSignifi"]
[365,"REACTOME_CHREBP_ACTIVATES_METABOLIC_GENE_EXPRESSION",-1.7027346243692,-0.0120468152297455,0.0997847461045237,0.0886414428114747,-0.186542451286292,-6.22477094180574,"NoSignifi"]
[366,"REACTOME_CONDENSATION_OF_PROMETAPHASE_CHROMOSOMES",-1.6879733436557,-0.0131438352296832,0.102818109849026,0.0914401273826017,-0.0872794216390266,-6.24973969036867,"NoSignifi"]
[367,"REACTOME_DEFECTS_IN_BIOTIN_BTN_METABOLISM",-1.68303433273011,-0.0115799754393019,0.10380994483797,0.0923922518497179,-0.207719145419483,-6.2580455231811,"NoSignifi"]
[368,"REACTOME_METHYLATION",-1.67940260474328,-0.013113971378018,0.104562631310812,0.0930974305091881,-0.161277881813563,-6.26413740397088,"NoSignifi"]
[369,"WP_MICRORNA_NETWORK_ASSOCIATED_WITH_CHRONIC_LYMPHOCYTIC_LEUKEMIA",-1.6728438722028,-0.0212728922936299,0.105925000271486,0.0943818912675418,-0.234822060743154,-6.27510573039913,"NoSignifi"]
[370,"REACTOME_LAGGING_STRAND_SYNTHESIS",-1.66021092218338,-0.0103230329896315,0.108664231678354,0.0968959393812043,-0.16660862991441,-6.29611121946931,"NoSignifi"]
[371,"REACTOME_NUCLEOTIDE_LIKE_PURINERGIC_RECEPTORS",-1.65620750815431,-0.00911818164456155,0.109528690694654,0.0977037308355817,0.146683836393318,-6.30273470073205,"NoSignifi"]
[372,"REACTOME_SYNTHESIS_OF_DOLICHYL_PHOSPHATE",-1.64756250451858,-0.013552855387116,0.111412913218797,0.0994664407878353,-0.248436531541231,-6.3169829717289,"NoSignifi"]
[373,"REACTOME_ASSEMBLY_OF_THE_ORC_COMPLEX_AT_THE_ORIGIN_OF_REPLICATION",-1.64452010944969,-0.0124669481544425,0.111952836553296,0.100092785717353,-0.195963382043176,-6.3219795667775,"NoSignifi"]
[374,"REACTOME_NEGATIVE_REGULATION_OF_TCF_DEPENDENT_SIGNALING_BY_DVL_INTERACTING_PROTEINS",-1.6424258443115,-0.0128830677490515,0.112394703016078,0.100525761705676,-0.172320473730491,-6.32541366194497,"NoSignifi"]
[375,"REACTOME_STRIATED_MUSCLE_CONTRACTION",-1.63189640036871,-0.00817336027169584,0.114724139645421,0.102725326119753,0.105851655571745,-6.34261315480838,"NoSignifi"]
[376,"REACTOME_DNA_REPLICATION_INITIATION",-1.61897310373176,-0.0138516049713415,0.117620062300735,0.10547710040329,-0.131098994148905,-6.36357178549354,"NoSignifi"]
[377,"REACTOME_LIPID_PARTICLE_ORGANIZATION",-1.60757756894355,-0.0144338362534101,0.120243949800142,0.107951805134338,0.0166507491656114,-6.38191454043269,"NoSignifi"]
[378,"REACTOME_ACYL_CHAIN_REMODELLING_OF_PE",-1.59407589925491,-0.0089468243270118,0.123436734998265,0.110943138338521,-0.0164416645475627,-6.40347979022972,"NoSignifi"]
[379,"REACTOME_FERTILIZATION",-1.56159858662812,-0.00670848506977523,0.131641975173008,0.118406715860742,0.298466254746129,-6.45460880122354,"NoSignifi"]
[380,"KEGG_GLYCINE_SERINE_AND_THREONINE_METABOLISM",-1.56114040586497,-0.00743248727846222,0.131712691237411,0.118514759625565,-0.0280106532761462,-6.45532258943274,"NoSignifi"]
[381,"REACTOME_FORMATION_OF_FIBRIN_CLOT_CLOTTING_CASCADE",-1.51725818062576,-0.00801866779248038,0.143186817624453,0.12922561981964,0.00471268340857426,-6.52271524820384,"NoSignifi"]
[382,"WP_NUCLEAR_RECEPTORS",-1.5098812074632,-0.00674624576776828,0.145207018406175,0.131097834431486,-0.140031116577313,-6.5338559444143,"NoSignifi"]
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[385,"KEGG_CIRCADIAN_RHYTHM_MAMMAL",-1.47610485689434,-0.0103671968085405,0.154826966791588,0.139939758446243,-0.26530700317774,-6.58417172950164,"NoSignifi"]
[386,"REACTOME_RUNX2_REGULATES_BONE_DEVELOPMENT",-1.46207955536073,-0.00742557911998004,0.158857332662791,0.143743375911473,-0.17398643602525,-6.60473051086894,"NoSignifi"]
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[388,"WP_ACQUIRED_PARTIAL_LIPODYSTROPHY_BARRAQUERSIMONS_SYNDROME",-1.44956408548693,-0.0112308721024552,0.162560638956196,0.147204033386784,-0.122429071058204,-6.62291046480129,"NoSignifi"]
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[393,"BIOCARTA_ERBB4_PATHWAY",-1.35042070443093,-0.0106567325317813,0.19420169678025,0.176904379658123,-0.184048159135479,-6.76140479929661,"NoSignifi"]
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[395,"REACTOME_DOWNSTREAM_SIGNALING_OF_ACTIVATED_FGFR4",-1.34682706234574,-0.00690191496555234,0.195324763041828,0.178059213812085,-0.120073958979709,-6.76624065173317,"NoSignifi"]
[396,"WP_SEROTONIN_AND_ANXIETYRELATED_EVENTS",-1.34529143246406,-0.0102149424080661,0.195795505962315,0.178554403716646,0.136734930789305,-6.76830317251473,"NoSignifi"]
[397,"BIOCARTA_CTL_PATHWAY",-1.3257369922978,-0.00971005042469547,0.202658624162192,0.184949925222243,0.197319337180182,-6.79436125404678,"NoSignifi"]
[398,"KEGG_ALANINE_ASPARTATE_AND_GLUTAMATE_METABOLISM",-1.31385451566468,-0.006246252895201,0.206777476734867,0.188918153508104,-0.0750982384733389,-6.81000942638861,"NoSignifi"]
[399,"REACTOME_FORMATION_OF_THE_CORNIFIED_ENVELOPE",-1.28124348693028,-0.00773617818717361,0.218485352872115,0.200130814118688,-0.0858427571212907,-6.85223155423951,"NoSignifi"]
[400,"REACTOME_SIGNALING_BY_INSULIN_RECEPTOR",-1.22014770432586,-0.00472982084262535,0.241850690744063,0.22243083096097,-0.139005786141811,-6.92847783125255,"NoSignifi"]
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[402,"BIOCARTA_COMP_PATHWAY",-1.18186907003688,-0.00558433008681891,0.257146333043309,0.237279089363512,0.306642141216645,-6.97435137876399,"NoSignifi"]
[403,"REACTOME_ACETYLCHOLINE_INHIBITS_CONTRACTION_OF_OUTER_HAIR_CELLS",-1.15346614715449,-0.00429005214517486,0.269075089257379,0.248740129745351,0.455805115102372,-7.00744503456791,"NoSignifi"]
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[406,"BIOCARTA_CK1_PATHWAY",-1.13012516407316,-0.00833530031074395,0.278758547786983,0.258444159689146,-0.157058982108399,-7.03403831989873,"NoSignifi"]
[407,"REACTOME_TRANSFERRIN_ENDOCYTOSIS_AND_RECYCLING",-1.1247739989882,-0.00670571096530713,0.281095241052936,0.260705404066978,-0.113650893842932,-7.04005852139006,"NoSignifi"]
[408,"KEGG_GLYCOSYLPHOSPHATIDYLINOSITOL_GPI_ANCHOR_BIOSYNTHESIS",-1.12334909040834,-0.00540940385772121,0.281644484873628,0.261309829083157,-0.243166368468304,-7.04165676469363,"NoSignifi"]
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[414,"REACTOME_FORMYL_PEPTIDE_RECEPTORS_BIND_FORMYL_PEPTIDES_AND_MANY_OTHER_LIGANDS",-1.01142122362616,-0.0117428894189094,0.333673135046862,0.311833530391298,-0.138623778413914,-7.16087129870682,"NoSignifi"]
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[416,"REACTOME_APEX1_INDEPENDENT_RESOLUTION_OF_AP_SITES_VIA_THE_SINGLE_NUCLEOTIDE_REPLACEMENT_PATHWAY",-0.976540862303523,-0.00685747498137404,0.351209459538842,0.328814524365819,-0.244417876681745,-7.19546794585438,"NoSignifi"]
[417,"WP_LIVER_X_RECEPTOR_PATHWAY",-0.976005900749231,-0.0088191262172114,0.351365912699457,0.329079545767103,-0.000942896012891906,-7.19598910471178,"NoSignifi"]
[418,"REACTOME_BIOSYNTHESIS_OF_THE_N_GLYCAN_PRECURSOR_DOLICHOL_LIPID_LINKED_OLIGOSACCHARIDE_LLO_AND_TRANSFER_TO_A_NASCENT_PROTEIN",-0.974857199598556,-0.00311119060619355,0.351847274878634,0.329649083109975,-0.137682676602487,-7.19710720307752,"NoSignifi"]
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[420,"WP_NAD_BIOSYNTHESIS_II_FROM_TRYPTOPHAN",-0.949654067668534,-0.00480261416111732,0.364830519848338,0.342305558602641,0.176789261874056,-7.22130757136852,"NoSignifi"]
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[422,"WP_HOMOLOGOUS_RECOMBINATION",-0.947500573589447,-0.00609892742003745,0.365603890569076,0.343401225149902,-0.175989143948814,-7.22334599427777,"NoSignifi"]
[423,"WP_KENNEDY_PATHWAY_FROM_SPHINGOLIPIDS",-0.939904224534912,-0.00563957002505663,0.369604950841133,0.34728400407980897,-0.220630869848196,-7.23049948717206,"NoSignifi"]
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[425,"REACTOME_DOWNSTREAM_SIGNALING_OF_ACTIVATED_FGFR3",-0.936604038104548,-0.00517842819307032,0.371142916546213,0.34897952375651,-0.161942098991838,-7.23358933775549,"NoSignifi"]
[426,"WP_PKCGAMMA_CALCIUM_SIGNALING_PATHWAY_IN_ATAXIA",-0.92840337463261,-0.00471648832531771,0.375378493423176,0.353215458217692,0.149979711306202,-7.24122028467634,"NoSignifi"]
[427,"REACTOME_INHIBITION_OF_REPLICATION_INITIATION_OF_DAMAGED_DNA_BY_RB1_E2F1",-0.926352608366367,-0.00681377327663107,0.376374683769633,0.354279813669796,-0.188056196387673,-7.24311809210531,"NoSignifi"]
[428,"SIG_CD40PATHWAYMAP",-0.91076027978307,-0.00450674315777189,0.384353319406663,0.362438437159792,-0.193015959346251,-7.25741020893708,"NoSignifi"]
[429,"REACTOME_FACTORS_INVOLVED_IN_MEGAKARYOCYTE_DEVELOPMENT_AND_PLATELET_PRODUCTION",-0.900512725598733,-0.00271531571053227,0.389967410705776,0.367863994714356,-0.10608282693104,-7.26667114011612,"NoSignifi"]
[430,"REACTOME_SYNTHESIS_OF_DIPHTHAMIDE_EEF2",-0.897629192202659,-0.00775256758686366,0.391315533740584,0.369399751486557,-0.228997960715234,-7.26925816057721,"NoSignifi"]
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[432,"BIOCARTA_DICER_PATHWAY",-0.887988181031451,-0.00827906535767226,0.396502110313419,0.374563397057211,-0.370555524552521,-7.27784754961455,"NoSignifi"]
[433,"WP_DEGRADATION_PATHWAY_OF_SPHINGOLIPIDS_INCLUDING_DISEASES",-0.875078781937107,-0.00749573693297315,0.403606536177857,0.381547069625626,-0.219079678735373,-7.28920358619442,"NoSignifi"]
[434,"WP_TYROBP_CAUSAL_NETWORK_IN_MICROGLIA",-0.871093670432521,-0.00241024963783111,0.405614476154221,0.383718957873292,0.103246187060035,-7.29267558887029,"NoSignifi"]
[435,"WP_MITOCHONDRIAL_FATTY_ACID_SYNTHESIS_PATHWAY",-0.856551505187293,-0.00851767514385993,0.412735103040437,0.391708449680415,-0.295314971744069,-7.30521094280366,"NoSignifi"]
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[437,"BIOCARTA_DNAFRAGMENT_PATHWAY",-0.836731263529674,-0.00681489172538888,0.423926616222475,0.402758890446184,-0.244565048464185,-7.3219562215657,"NoSignifi"]
[438,"REACTOME_WNT_MEDIATED_ACTIVATION_OF_DVL",-0.829139923806789,-0.00790346516989404,0.427825365907389,0.407040327887597,-0.270339317143413,-7.32826600652226,"NoSignifi"]
[439,"REACTOME_RRNA_PROCESSING_IN_THE_MITOCHONDRION",-0.807623300742556,-0.00607818262303353,0.440265944654163,0.419322119351789,-0.23204413569807,-7.34583777526345,"NoSignifi"]
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[442,"REACTOME_PHASE_II_CONJUGATION_OF_COMPOUNDS",-0.695900312909571,-0.00228433064518075,0.508461444384274,0.486503595234076,-0.0331774452234343,-7.42965083114945,"NoSignifi"]
[443,"WP_4HYDROXYTAMOXIFEN_DEXAMETHASONE_AND_RETINOIC_ACIDS_REGULATION_OF_P27_EXPRESSION",-0.687649171515957,-0.00426160825786642,0.513696511573008,0.491685898560265,-0.247157688675185,-7.43534683906236,"NoSignifi"]
[444,"REACTOME_ESTABLISHMENT_OF_SISTER_CHROMATID_COHESION",-0.672770879490094,-0.00549704191994749,0.523168365696252,0.50110492247357,-0.295794146682508,-7.44544607425151,"NoSignifi"]
[445,"BIOCARTA_EPHA4_PATHWAY",-0.663587374274873,-0.0060534500308768,0.528728902476161,0.506966106895158,-0.103751460415669,-7.45156949780036,"NoSignifi"]
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[448,"REACTOME_INTERLEUKIN_RECEPTOR_SHC_SIGNALING",-0.590413357709499,-0.0029346095959723,0.576311823082657,0.554923732482424,-0.0397606470567549,-7.49735408823161,"NoSignifi"]
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[450,"WP_MEVALONATE_PATHWAY",-0.585801816031905,-0.00576352923973228,0.579120336251245,0.558018785537636,-0.229772649775421,-7.50006053305591,"NoSignifi"]
[451,"REACTOME_TRANSPORT_OF_THE_SLBP_DEPENDANT_MATURE_MRNA",-0.572430512176064,-0.00259859839227305,0.587865353490168,0.567040163842237,-0.316398612715463,-7.50778798031651,"NoSignifi"]
[452,"REACTOME_FRS_MEDIATED_FGFR4_SIGNALING",-0.560181852377936,-0.00319090092963002,0.596078917625687,0.575364974131947,-0.0495937056357464,-7.51471006594182,"NoSignifi"]
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[457,"WP_FATTY_ACID_TRANSPORTERS",-0.499011370252208,-0.00357600522847076,0.636897401121305,0.617779745431443,-0.073205317543062,-7.54703856177742,"NoSignifi"]
[458,"REACTOME_POST_CHAPERONIN_TUBULIN_FOLDING_PATHWAY",-0.481809605217046,-0.00405799163957168,0.648322766359511,0.629949246665112,-0.145441536618354,-7.555457019071,"NoSignifi"]
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[460,"REACTOME_ACTIVATED_NTRK3_SIGNALS_THROUGH_PI3K",-0.44721384435379,-0.00437409541596741,0.672190491872736,0.654728053318688,0.0257757292866733,-7.57149390843382,"NoSignifi"]
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[465,"WP_STRIATED_MUSCLE_CONTRACTION_PATHWAY",-0.36506096846267,-0.00187774194997629,0.731012659630594,0.715071783680959,0.0815118061180868,-7.60479036125423,"NoSignifi"]
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[467,"REACTOME_SIGNALING_BY_TYPE_1_INSULIN_LIKE_GROWTH_FACTOR_1_RECEPTOR_IGF1R",-0.356537390199914,-0.00136772805072652,0.736857235809647,0.721443892820376,-0.126142222408651,-7.60785931901136,"NoSignifi"]
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[469,"REACTOME_ACTIVATION_OF_NOXA_AND_TRANSLOCATION_TO_MITOCHONDRIA",-0.290540566940388,-0.00293712655054795,0.785722090343428,0.771407315418143,-0.342386925072164,-7.62916786757387,"NoSignifi"]
[470,"REACTOME_SYNTHESIS_OF_GDP_MANNOSE",-0.279928500083629,-0.00255135186884226,0.793184691453051,0.779536776721571,-0.265797881587078,-7.6321885642554,"NoSignifi"]
[471,"REACTOME_RUNX2_REGULATES_CHONDROCYTE_MATURATION",-0.275734970866198,-0.00223242692868761,0.796186932405889,0.782755978755317,-0.101655917257533,-7.63335126165349,"NoSignifi"]
[472,"REACTOME_INTERACTIONS_OF_VPR_WITH_HOST_CELLULAR_PROTEINS",-0.258587555924012,-0.0012527809080996,0.809059726291734,0.795957544489439,-0.290002662781906,-7.63792295942491,"NoSignifi"]
[473,"WP_CHOLESTEROL_BIOSYNTHESIS_PATHWAY",-0.211239965622978,-0.00166417968821039,0.844094599190124,0.832703309052605,-0.247845649905332,-7.64902268460398,"NoSignifi"]
[474,"REACTOME_STAT5_ACTIVATION_DOWNSTREAM_OF_FLT3_ITD_MUTANTS",-0.207239000151109,-0.00178777020371562,0.846970781210942,0.835826428826588,-0.164989298079182,-7.64985812356607,"NoSignifi"]
[475,"PID_CONE_PATHWAY",-0.191713897819974,-0.00089909130484811,0.858688407405604,0.847969287610055,0.25178733837089,-7.65294865037257,"NoSignifi"]
[476,"REACTOME_SYNTHESIS_OF_VERY_LONG_CHAIN_FATTY_ACYL_COAS",-0.186809813820536,-0.00112842424813084,0.861991352500224,0.851812642197421,-0.136167731950568,-7.65387489892652,"NoSignifi"]
[477,"WP_NICOTINE_EFFECT_ON_DOPAMINERGIC_NEURONS",-0.174431030926374,-0.0010223258503062,0.870932198722956,0.861529421948619,0.0672841022447937,-7.65610616546987,"NoSignifi"]
[478,"REACTOME_CREB_PHOSPHORYLATION",-0.155463029181768,-0.00128786824311478,0.885420436323817,0.876458691016895,-0.318421605970555,-7.65922845313154,"NoSignifi"]
[479,"BIOCARTA_ATM_PATHWAY",-0.15494192103685,-0.0010275203393362,0.885533617154485,0.876869489321327,-0.218081253883744,-7.65930916426494,"NoSignifi"]
[480,"REACTOME_SYNTHESIS_OF_5_EICOSATETRAENOIC_ACIDS",-0.148993026148911,-0.00124641817622985,0.889462099477963,0.881561427162101,-0.0124568839866504,-7.66021134574932,"NoSignifi"]
[481,"REACTOME_BRANCHED_CHAIN_AMINO_ACID_CATABOLISM",-0.148868356202509,-0.000808120917576288,0.889462099477963,0.881659800359735,-0.212823610235182,-7.66022987479204,"NoSignifi"]
[482,"REACTOME_DERMATAN_SULFATE_BIOSYNTHESIS",-0.126142505592069,-0.000943454338926716,0.907273497381588,0.899621055602053,-0.0652017662444122,-7.66334838453071,"NoSignifi"]
[483,"REACTOME_UNBLOCKING_OF_NMDA_RECEPTORS_GLUTAMATE_BINDING_AND_ACTIVATION",-0.11917780754822,-0.000512598691164129,0.911904838506186,0.905136314063832,0.16875154591113,-7.66420092115473,"NoSignifi"]
[484,"WP_METHIONINE_METABOLISM_LEADING_TO_SULFUR_AMINO_ACIDS_AND_RELATED_DISORDERS",-0.107930877346128,-0.000850593150673359,0.920037461426223,0.914052174978047,-0.0479978502231291,-7.66547543646177,"NoSignifi"]
[485,"WP_IMATINIB_AND_CHRONIC_MYELOID_LEUKEMIA",-0.100798114448499,-0.000564742490006112,0.925331687995375,0.919712264788925,-0.0901718020704859,-7.66621831522413,"NoSignifi"]
[486,"REACTOME_MITOCHONDRIAL_FATTY_ACID_BETA_OXIDATION",-0.0983238774980637,-0.000503243879964727,0.926993385148474,0.921676621468472,-0.110948091000763,-7.66646414695031,"NoSignifi"]
[487,"REACTOME_SENSORY_PERCEPTION_OF_TASTE",-0.0682737687843996,-0.000246693456550484,0.949734246978869,0.945568745895628,0.266975300002517,-7.66896214682874,"NoSignifi"]
[488,"REACTOME_RHO_GTPASES_ACTIVATE_NADPH_OXIDASES",-0.0514945312434264,-0.000309877906380207,0.962504290866007,0.958932243902604,-0.165824281011519,-7.66996489465436,"NoSignifi"]
[489,"BIOCARTA_CD40_PATHWAY",-0.0471153438132222,-0.000347178059618952,0.965353250424636,0.962422015858569,-0.218721523311999,-7.67018036703086,"NoSignifi"]
[490,"REACTOME_IRON_UPTAKE_AND_TRANSPORT",-0.04339930415637,-0.000246384533282157,0.967733863177973,0.965383893214163,-0.126200403119078,-7.67034819984768,"NoSignifi"]
[491,"BIOCARTA_FREE_PATHWAY",-0.0349365234676904,-0.000292090696216413,0.97410275658694,0.972130888658626,-0.223623190683576,-7.67067898896482,"NoSignifi"]
[492,"REACTOME_AFLATOXIN_ACTIVATION_AND_DETOXIFICATION",-0.0343447681835415,-0.00023013727448927,0.974246214111559,0.972602748838092,-0.0565962103957586,-7.67069944567629,"NoSignifi"]
[493,"WP_IRON_METABOLISM_IN_PLACENTA",-0.0203642765890743,-0.000139877442598996,0.985082487013072,0.983753090944229,-0.107111614757113,-7.67108109042367,"NoSignifi"]
[494,"REACTOME_NEGATIVE_REGULATION_OF_FGFR2_SIGNALING",-0.0133944983681309,{"v":-7.84104950513898e-05,"d":"-7.84E-05"},0.990315603625313,0.989313259896948,-0.144478637699062,-7.67119849455169,"NoSignifi"]
[495,"REACTOME_ELEVATION_OF_CYTOSOLIC_CA2_LEVELS",-0.009664457772544,{"v":-6.962765880969e-05,"d":"-6.96E-05"},0.992624038819255,0.992289145418844,-0.0854341915035472,-7.67124141170927,"NoSignifi"]
[496,"REACTOME_NEGATIVE_FEEDBACK_REGULATION_OF_MAPK_PATHWAY",0.00181926684868237,{"v":1.841016709625e-05,"d":"1.84E-05"},0.998548463545745,0.998548463545745,-0.295865193760012,-7.67128636526361,"NoSignifi"]
[497,"REACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS_VIA_7ALPHA_HYDROXYCHOLESTEROL",0.0109610035227861,{"v":6.69274472476639e-05,"d":"6.69E-05"},0.991924040858113,0.991254726390598,-0.0981285756539782,-7.67122806822403,"NoSignifi"]
[498,"REACTOME_IRF3_MEDIATED_ACTIVATION_OF_TYPE_1_IFN",0.0433183895446315,0.000503169388130609,0.967733863177973,0.965448391841183,-0.143646244467084,-7.67035170100964,"NoSignifi"]
[499,"REACTOME_ACYL_CHAIN_REMODELLING_OF_PS",0.0497574223725669,0.000286243702842363,0.963567356533137,0.960316454520542,0.0228664825995881,-7.67005265697698,"NoSignifi"]
[500,"KEGG_HISTIDINE_METABOLISM",0.062690248335749,0.000326200334112486,0.953875964372064,0.950014118362461,-0.116445953309635,-7.66932701644416,"NoSignifi"]
[501,"REACTOME_SYNTHESIS_OF_PIPS_AT_THE_ER_MEMBRANE",0.0716261175465481,0.000591079492026081,0.947375329307592,0.942900547050404,-0.286831430432909,-7.66872813159336,"NoSignifi"]
[502,"REACTOME_METABOLIC_DISORDERS_OF_BIOLOGICAL_OXIDATION_ENZYMES",0.0754807259590643,0.000330840465006213,0.944613818047522,0.939833383745662,-0.0377460562711115,-7.66844519396794,"NoSignifi"]
[503,"REACTOME_ACYL_CHAIN_REMODELLING_OF_PI",0.0837393787952306,0.0005944120691046,0.938330135565245,0.933264925656661,-0.0392925471936837,-7.66778907189731,"NoSignifi"]
[504,"KEGG_OLFACTORY_TRANSDUCTION",0.107820431060031,0.000323079798792952,0.920037461426223,0.91413978539144,0.215668813197498,-7.66548732646227,"NoSignifi"]
[505,"WP_FGFR3_SIGNALING_IN_CHONDROCYTE_PROLIFERATION_AND_TERMINAL_DIFFERENTIATION",0.11669432236946,0.00067000970412523,0.913576786829204,0.907104076801062,-0.185978345818979,-7.66449321218075,"NoSignifi"]
[506,"REACTOME_TYSND1_CLEAVES_PEROXISOMAL_PROTEINS",0.11926448093103,0.00107409686243415,0.911904838506186,0.905067649789794,-0.289094324577313,-7.66419060907468,"NoSignifi"]
[507,"REACTOME_ASSEMBLY_AND_CELL_SURFACE_PRESENTATION_OF_NMDA_RECEPTORS",0.122471636682042,0.000570242817894658,0.909894954916282,0.90252738443113,0.00761228392722557,-7.66380376241491,"NoSignifi"]
[508,"REACTOME_STIMULI_SENSING_CHANNELS",0.151589713179773,0.000470423993252657,0.887900604434137,0.879512879425987,-0.0111577976963155,-7.65982188773941,"NoSignifi"]
[509,"REACTOME_MEIOSIS",0.169302990275918,0.000691340934041745,0.874709380614771,0.865560935675818,-0.141118940906324,-7.65698569563488,"NoSignifi"]
[510,"KEGG_GLYCOSPHINGOLIPID_BIOSYNTHESIS_GLOBO_SERIES",0.179661696478559,0.000895477793014979,0.867074606642472,0.857420941993619,0.0716069031997101,-7.65518199803641,"NoSignifi"]
[511,"REACTOME_CA_DEPENDENT_EVENTS",0.181198150656162,0.000717162740020968,0.866150445659474,0.856214846755148,-0.0716456356286521,-7.65490534538501,"NoSignifi"]
[512,"WP_FAMILIAL_HYPERLIPIDEMIA_TYPE_2",0.189378546148965,0.00120659174219674,0.860247418318533,0.849799069108187,0.00691361128201999,-7.65339272827549,"NoSignifi"]
[513,"REACTOME_SIGNALING_BY_MRAS_COMPLEX_MUTANTS",0.197465938956311,0.0019001163448783,0.85442009804792,0.843465994226793,-0.198846436314059,-7.65183166162069,"NoSignifi"]
[514,"REACTOME_TRIF_MEDIATED_PROGRAMMED_CELL_DEATH",0.211852039948576,0.00129458245063334,0.843899129053241,0.832225760533948,0.109634181206347,-7.64889346891754,"NoSignifi"]
[515,"REACTOME_RETROGRADE_NEUROTROPHIN_SIGNALLING",0.213079070132779,0.00183758177973697,0.843217021289619,0.831268601959604,-0.186423204694485,-7.64863330323103,"NoSignifi"]
[516,"WP_NOCGMPPKG_MEDIATED_NEUROPROTECTION",0.222181159758461,0.000894237885477628,0.836309008274069,0.824176320232306,-0.000516955444122359,-7.64665648715473,"NoSignifi"]
[517,"KEGG_GLYCOSPHINGOLIPID_BIOSYNTHESIS_GANGLIO_SERIES",0.224307559549814,0.0010566221458724,0.834915648744658,0.822521489316599,0.0604820724809673,-7.64618275648854,"NoSignifi"]
[518,"REACTOME_TRAFFICKING_AND_PROCESSING_OF_ENDOSOMAL_TLR",0.233823258597763,0.00207438974025223,0.827692016965901,0.815125842619252,-0.18697166775185,-7.64400752137396,"NoSignifi"]
[519,"REACTOME_SLC_TRANSPORTER_DISORDERS",0.235702516454061,0.000660741823762676,0.826494028590208,0.813667198186986,-0.112826433415287,-7.64356724870535,"NoSignifi"]
[520,"REACTOME_GLUTATHIONE_CONJUGATION",0.250674580647044,0.00136881342775398,0.814992945077919,0.802069642642473,-0.103861488360439,-7.63993370344558,"NoSignifi"]
[521,"WP_GENE_REGULATORY_NETWORK_MODELLING_SOMITOGENESIS",0.265217619412358,0.00207520873753729,0.80413980074047,0.790845991618917,-0.0629251538858037,-7.63619010157791,"NoSignifi"]
[522,"REACTOME_REGULATION_OF_GLYCOLYSIS_BY_FRUCTOSE_2_6_BISPHOSPHATE_METABOLISM",0.280137157268246,0.00231591943210227,0.793184691453051,0.779376697287628,-0.168116949385079,-7.63213025366734,"NoSignifi"]
[523,"REACTOME_TRANSLESION_SYNTHESIS_BY_POLH",0.282817947898653,0.00223119156366963,0.791473386496301,0.777320859679735,-0.181326193656877,-7.63137722454726,"NoSignifi"]
[524,"REACTOME_TRNA_MODIFICATION_IN_THE_MITOCHONDRION",0.290917946596531,0.00227318959207118,0.785698094591463,0.771118676506939,-0.266181921206728,-7.62905837815406,"NoSignifi"]
[525,"REACTOME_GAMMA_CARBOXYLATION_HYPUSINE_FORMATION_AND_ARYLSULFATASE_ACTIVATION",0.292870692859624,0.00122625501671042,0.784446476278065,0.769625625174296,-0.143321319485392,-7.62848955617654,"NoSignifi"]
[526,"REACTOME_OVARIAN_TUMOR_DOMAIN_PROTEASES",0.301667056767224,0.0016499494418088,0.777869700564798,0.762910667861629,-0.204138867686246,-7.62588005539516,"NoSignifi"]
[527,"SA_CASPASE_CASCADE",0.304620766007742,0.00180367761850039,0.775841622866382,0.760659836723922,-0.244198984540011,-7.62498650041394,"NoSignifi"]
[528,"REACTOME_DEPOSITION_OF_NEW_CENPA_CONTAINING_NUCLEOSOMES_AT_THE_CENTROMERE",0.318350054827477,0.00169847450298938,0.765724995542069,0.750224489559436,-0.127445698215348,-7.6207188359502,"NoSignifi"]
[529,"REACTOME_CLASS_A_1_RHODOPSIN_LIKE_RECEPTORS",0.34744661130577,0.000778750045720866,0.74356416897777,0.728261397618916,0.308084973249981,-7.61105260278102,"NoSignifi"]
[530,"REACTOME_SYNTHESIS_OF_GLYCOSYLPHOSPHATIDYLINOSITOL_GPI",0.357509982947865,0.00196181186653949,0.73636734059522,0.720715808052205,-0.254015202101762,-7.60751279641164,"NoSignifi"]
[531,"REACTOME_NITRIC_OXIDE_STIMULATES_GUANYLATE_CYCLASE",0.369689796118441,0.00129724720866647,0.727826263481406,0.711619605792549,0.406740585809291,-7.60309335157161,"NoSignifi"]
[532,"REACTOME_MECP2_REGULATES_NEURONAL_RECEPTORS_AND_CHANNELS",0.374186762442929,0.00231507975780154,0.724651879892344,0.708271422418395,-0.244024464329316,-7.60142420813681,"NoSignifi"]
[533,"REACTOME_IRAK4_DEFICIENCY_TLR2_4",0.383588558939775,0.00300744622588631,0.718004315653571,0.701289640289166,-0.113786472310779,-7.59786933357726,"NoSignifi"]
[534,"WP_ANTIVIRAL_AND_ANTIINFLAMMATORY_EFFECTS_OF_NRF2_ON_SARSCOV2_PATHWAY",0.389348311064154,0.0018290786070009,0.713884445095401,0.697024825946724,-0.0556845902356396,-7.59564796511266,"NoSignifi"]
[535,"WP_ETHANOL_EFFECTS_ON_HISTONE_MODIFICATIONS",0.402824354514674,0.00191664815114681,0.703946424938241,0.687084010575685,-0.202018207499428,-7.5903213074187,"NoSignifi"]
[536,"REACTOME_METALLOPROTEASE_DUBS",0.418691371642628,0.00304983890621988,0.692504161860089,0.6754485600329,-0.242639467664048,-7.58381726579718,"NoSignifi"]
[537,"KEGG_GLYCOSAMINOGLYCAN_DEGRADATION",0.420238895029042,0.00224204040858142,0.691584099408255,0.674317829719925,-0.132010880602563,-7.58316947468303,"NoSignifi"]
[538,"REACTOME_HDMS_DEMETHYLATE_HISTONES",0.457291487903767,0.00277430202294676,0.664968288800032,0.647469123305295,-0.279364135438554,-7.56694569248193,"NoSignifi"]
[539,"WP_BIOMARKERS_FOR_UREA_CYCLE_DISORDERS",0.460375326193639,0.00342976433171058,0.66292348961701,0.645254476229782,-0.0295849386872378,-7.56553365125369,"NoSignifi"]
[540,"REACTOME_GLUCURONIDATION",0.460572680700764,0.00277685913198616,0.66292348961701,0.645112853620601,0.168183716708979,-7.56544296261864,"NoSignifi"]
[541,"REACTOME_HDL_ASSEMBLY",0.462782934464077,0.00357743713571837,0.661837591427057,0.643527644565715,-0.109657362240217,-7.56442464841734,"NoSignifi"]
[542,"REACTOME_HORMONE_LIGAND_BINDING_RECEPTORS",0.474956648152235,0.00150683692609288,0.653114759965577,0.634825783893666,0.421526020520024,-7.55872857240993,"NoSignifi"]
[543,"WP_PROSTAGLANDIN_AND_LEUKOTRIENE_METABOLISM_IN_SENESCENCE",0.481877351501892,0.0021434295435088,0.648322766359511,0.629901118632365,-0.0367047985862385,-7.5554244435412,"NoSignifi"]
[544,"REACTOME_INOSITOL_PHOSPHATE_METABOLISM",0.484118155953593,0.00188211243221277,0.647085178218587,0.6283101021974,-0.0675396182590587,-7.55434438060203,"NoSignifi"]
[545,"PID_ERBB4_PATHWAY",0.486465246747703,0.00245334273183181,0.645595124686251,0.626645470216715,-0.232975155487451,-7.55320771510954,"NoSignifi"]
[546,"REACTOME_TRANSPORT_OF_MATURE_MRNAS_DERIVED_FROM_INTRONLESS_TRANSCRIPTS",0.498715532344308,0.00211866520632986,0.636897401121305,0.617988166540106,-0.321774102411549,-7.54718583879662,"NoSignifi"]
[547,"BIOCARTA_TALL1_PATHWAY",0.503147331062509,0.00308523540856145,0.634123917838001,0.614869143004864,-0.126444510563887,-7.54497041039459,"NoSignifi"]
[548,"REACTOME_FREE_FATTY_ACIDS_REGULATE_INSULIN_SECRETION",0.5049345626343,0.00343619832449613,0.633048998363502,0.613613283501464,-0.0844398682205355,-7.54407143883532,"NoSignifi"]
[549,"REACTOME_CHYLOMICRON_ASSEMBLY",0.507443328175796,0.00510617607215258,0.631671993162131,0.611852325360485,-0.0293007944686094,-7.54280416063194,"NoSignifi"]
[550,"REACTOME_CGMP_EFFECTS",0.510172357983337,0.00205305411973988,0.629916409423757,0.609939303321924,0.40612140205439,-7.54141848614403,"NoSignifi"]
[551,"REACTOME_ACTIVATION_OF_PPARGC1A_PGC_1ALPHA_BY_PHOSPHORYLATION",0.510298627383974,0.00333785670918343,0.629916409423757,0.609850854107286,-0.137253614786406,-7.54135419252402,"NoSignifi"]
[552,"REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS",0.517337636230288,0.00268393881333556,0.62517788894841,0.604929212383279,0.129561925716149,-7.53774491804054,"NoSignifi"]
[553,"WP_MITOCHONDRIAL_COMPLEX_II_ASSEMBLY",0.531680170210995,0.00441071535193843,0.615300478331952,0.594956535391152,-0.291372610644977,-7.5302377289183,"NoSignifi"]
[554,"REACTOME_CREATINE_METABOLISM",0.546684958047435,0.00456848943520399,0.605227983230093,0.584604492573467,-0.166983348147227,-7.5221641929354,"NoSignifi"]
[555,"BIOCARTA_IL3_PATHWAY",0.558719562458466,0.0039223754804952,0.596903894485775,0.5763626673476,-0.238724305508963,-7.51552644651769,"NoSignifi"]
[556,"WP_GANGLIO_SPHINGOLIPID_METABOLISM",0.562916009670654,0.00289203403108204,0.594356309819912,0.57350170245781,0.04727048321367,-7.5131778909426,"NoSignifi"]
[557,"WP_SPHINGOLIPID_METABOLISM_IN_SENESCENCE",0.579863043249147,0.00309356138391861,0.582861517907843,0.562016942706011,-0.184049624648638,-7.50351464875466,"NoSignifi"]
[558,"REACTOME_ETHANOL_OXIDATION",0.58260010817146,0.00397807446982337,0.581152061586468,0.560172550591275,0.00912067869234877,-7.50192708628712,"NoSignifi"]
[559,"WP_INTRACELLULAR_TRAFFICKING_PROTEINS_INVOLVED_IN_CMT_NEUROPATHY",0.595118769356989,0.00390799043302409,0.573241914734627,0.551774353150436,-0.143276344207644,-7.49457067921227,"NoSignifi"]
[560,"REACTOME_TRANSPORT_OF_CONNEXONS_TO_THE_PLASMA_MEMBRANE",0.597974382433208,0.0058245570580884,0.571461022930266,0.549867354047611,-0.130845885781448,-7.49287071552401,"NoSignifi"]
[561,"WP_CANCER_IMMUNOTHERAPY_BY_CTLA4_BLOCKADE",0.610291958587725,0.00468236707274441,0.563346159685132,0.541678999697242,-0.139806297071096,-7.4854447392012,"NoSignifi"]
[562,"BIOCARTA_TERC_PATHWAY",0.635834414611518,0.0056461300102803,0.546274619616328,0.524895450967376,-0.345678254596842,-7.46956330961317,"NoSignifi"]
[563,"WP_SPHINGOLIPID_PATHWAY",0.645911060183322,0.00362401831244161,0.539650243019928,0.518348259742825,-0.181065086524296,-7.46311891857239,"NoSignifi"]
[564,"REACTOME_NOSTRIN_MEDIATED_ENOS_TRAFFICKING",0.653457045805193,0.0076116715592042,0.53476260008385,0.513473130849743,-0.175789499821802,-7.45822663178341,"NoSignifi"]
[565,"BIOCARTA_NO1_PATHWAY",0.658428554793163,0.00424784912892315,0.531617989470135,0.510274352241071,-0.0375267004371043,-7.45497240619979,"NoSignifi"]
[566,"REACTOME_ACTIVATED_TAK1_MEDIATES_P38_MAPK_ACTIVATION",0.66128015071428,0.00455559110975753,0.529897632994396,0.508444287529036,-0.209756841715463,-7.45309469257805,"NoSignifi"]
[567,"REACTOME_VITAMIN_B5_PANTOTHENATE_METABOLISM",0.662030600568603,0.00386054897599253,0.529582503877577,0.507963245116043,-0.0950791190353193,-7.45259918907471,"NoSignifi"]
[568,"BIOCARTA_BIOPEPTIDES_PATHWAY",0.663976821189304,0.00411131396425762,0.528654930385909,0.506716820926575,-0.226857587390114,-7.45131152915957,"NoSignifi"]
[569,"REACTOME_SHC_MEDIATED_CASCADE_FGFR4",0.66571750091252,0.0039879459758509,0.527679036762942,0.505603395548838,-0.0173945792016172,-7.45015665741568,"NoSignifi"]
[570,"REACTOME_REDUCTION_OF_CYTOSOLIC_CA_LEVELS",0.674908983784783,0.00570896232683537,0.521932924392759,0.49974549238416,-0.0557376743637196,-7.44400834106807,"NoSignifi"]
[571,"WP_INTERLEUKIN1_IL1_STRUCTURAL_PATHWAY",0.70993138530146,0.00334740044729365,0.499498623832724,0.477759311257008,-0.252661910173163,-7.41980878181314,"NoSignifi"]
[572,"WP_GDNFRET_SIGNALING_AXIS",0.713578549741655,0.00384256952303778,0.497312476392208,0.475500525673251,0.0371865742807232,-7.41721832250381,"NoSignifi"]
[573,"REACTOME_HDL_CLEARANCE",0.714494769819245,0.00693065035894598,0.496895305690148,0.474934008441359,0.052794154699672,-7.41656547592898,"NoSignifi"]
[574,"REACTOME_ALPHA_LINOLENIC_OMEGA3_AND_LINOLEIC_OMEGA6_ACID_METABOLISM",0.730365806979194,0.00531639761854449,0.486861764819263,0.465179661932575,-0.195905544135403,-7.40512374666301,"NoSignifi"]
[575,"REACTOME_GPCR_LIGAND_BINDING",0.756371351272954,0.00121938717602349,0.470721081022147,0.449440168452319,0.272976580331147,-7.385832533538,"NoSignifi"]
[576,"SA_G2_AND_M_PHASES",0.761659940626812,0.00624142806163108,0.467573031180706,0.446276688667415,-0.171158282944237,-7.38182682643377,"NoSignifi"]
[577,"REACTOME_SIGNALING_BY_LEPTIN",0.765066018770614,0.00590860419047584,0.465610025486084,0.444246002724239,-0.204784944444046,-7.37923220442092,"NoSignifi"]
[578,"REACTOME_NEGATIVE_REGULATION_OF_FGFR1_SIGNALING",0.774509288155987,0.00458311688653482,0.460063608487103,0.438643642909768,-0.139653977689908,-7.37197814031993,"NoSignifi"]
[579,"PID_CD40_PATHWAY",0.782634849512428,0.00439630249799308,0.455202940693609,0.433855704271068,-0.21633270913197,-7.36566508185781,"NoSignifi"]
[580,"REACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS_VIA_27_HYDROXYCHOLESTEROL",0.78997712398229,0.00604958629691563,0.450850653951258,0.429555413886084,-0.155713637170494,-7.35990392879685,"NoSignifi"]
[581,"KEGG_HOMOLOGOUS_RECOMBINATION",0.817731565441501,0.00408729028636078,0.434333490488074,0.41352534080882,-0.0783063464664734,-7.33764029042188,"NoSignifi"]
[582,"KEGG_LIMONENE_AND_PINENE_DEGRADATION",0.819231311681459,0.00722711223566172,0.43358806544517,0.412669342989482,-0.161949228414601,-7.3364153580305,"NoSignifi"]
[583,"REACTOME_NEGATIVE_REGULATION_OF_FGFR3_SIGNALING",0.833175551201798,0.00528575185490313,0.425580461961459,0.404760904949174,-0.150608019264627,-7.32491882456087,"NoSignifi"]
[584,"BIOCARTA_PKC_PATHWAY",0.834576203359744,0.00785241321427096,0.424901253688392,0.403971569802256,-0.230520854110535,-7.32375331359501,"NoSignifi"]
[585,"REACTOME_NEGATIVE_REGULATION_OF_FGFR4_SIGNALING",0.834965826811764,0.00493319878692325,0.424821231249354,0.403752162088202,-0.13171400302319,-7.32342875205308,"NoSignifi"]
[586,"REACTOME_DISEASES_OF_CARBOHYDRATE_METABOLISM",0.855119074730735,0.00524245945808706,0.413423075172052,0.392500854768608,-0.120157490051186,-7.30643428276951,"NoSignifi"]
[587,"REACTOME_REGULATION_OF_TP53_ACTIVITY_THROUGH_METHYLATION",0.857680875361055,0.0061783433522038,0.412224075479166,0.391084379300747,-0.261748004502708,-7.30424498230616,"NoSignifi"]
[588,"WP_PROTEOGLYCAN_BIOSYNTHESIS",0.859089722847536,0.00451325844104741,0.411550737427172,0.390306721628806,-0.197944831676406,-7.30303819833154,"NoSignifi"]
[589,"PID_TCR_RAS_PATHWAY",0.860886329147914,0.00614843378186894,0.410652593886746,0.389316392989796,-0.242711416144328,-7.30149639665629,"NoSignifi"]
[590,"REACTOME_NEF_MEDIATED_CD4_DOWN_REGULATION",0.861922734965192,0.00725648191691869,0.410196706960216,0.388745799544955,-0.169745275719735,-7.3006055148208,"NoSignifi"]
[591,"WP_DEVELOPMENT_OF_PULMONARY_DENDRITIC_CELLS_AND_MACROPHAGE_SUBSETS",0.863754375040855,0.00568199881072952,0.409279671002172,0.387738635686268,0.0675741932069571,-7.29902843851336,"NoSignifi"]
[592,"KEGG_PANTOTHENATE_AND_COA_BIOSYNTHESIS",0.865949850298524,0.00485822987082778,0.408152945258654,0.386533507874846,0.0628835336075216,-7.29713368243226,"NoSignifi"]
[593,"REACTOME_MITOCHONDRIAL_FATTY_ACID_BETA_OXIDATION_OF_SATURATED_FATTY_ACIDS",0.869023398994296,0.00739089871480542,0.406520351847307,0.384850238624677,-0.159396614416508,-7.29447304530988,"NoSignifi"]
[594,"REACTOME_GROWTH_HORMONE_RECEPTOR_SIGNALING",0.869995756357481,0.00538027250136222,0.406103556504171,0.38431864912085,-0.24485611287398,-7.29362935527208,"NoSignifi"]
[595,"REACTOME_WNT5A_DEPENDENT_INTERNALIZATION_OF_FZD4",0.872937927913613,0.00648867611969536,0.404695336000427,0.382712897034142,-0.121798637158288,-7.29107076119162,"NoSignifi"]
[596,"WP_STEROID_BIOSYNTHESIS",0.880694194438944,0.00891545255820844,0.400525713161231,0.378499501540017,-0.163653209649477,-7.28428429889652,"NoSignifi"]
[597,"REACTOME_COPI_DEPENDENT_GOLGI_TO_ER_RETROGRADE_TRAFFIC",0.899510564735669,0.00360177637624851,0.390393123479233,0.368397289598993,-0.119261942235029,-7.26757118966656,"NoSignifi"]
[598,"REACTOME_SIRT1_NEGATIVELY_REGULATES_RRNA_EXPRESSION",0.911526025502312,0.00787496592823037,0.384062937776076,0.362035036486625,-0.220392709009993,-7.2567139811114,"NoSignifi"]
[599,"WP_IRINOTECAN_PATHWAY",0.915031066056379,0.00590021787675651,0.3822447284414,0.360192147954396,0.00659872164596842,-7.25351967629259,"NoSignifi"]
[600,"REACTOME_PREVENTION_OF_PHAGOSOMAL_LYSOSOMAL_FUSION",0.915309711256393,0.0109722959874345,0.382226372120236,0.360045894385863,-0.216421494477992,-7.25326520812313,"NoSignifi"]
[601,"REACTOME_ACTIVATED_NTRK2_SIGNALS_THROUGH_FYN",0.920878501151613,0.00845883751794602,0.379267541657469,0.357130805926449,-0.0345542045015638,-7.24816335685953,"NoSignifi"]
[602,"REACTOME_METALLOTHIONEINS_BIND_METALS",0.931399509916493,0.00970887289251188,0.373863834291444,0.351664092444179,-0.118569902366161,-7.2384400761075,"NoSignifi"]
[603,"REACTOME_FORMATION_OF_APOPTOSOME",0.948060286450169,0.00780187934542748,0.365465271370119,0.343116236104271,-0.256562479333206,-7.22281663449222,"NoSignifi"]
[604,"REACTOME_SUMOYLATION_OF_DNA_REPLICATION_PROTEINS",0.965489970642161,0.00415996316075118,0.356573000393815,0.334317263189747,-0.245795128129148,-7.20617573692288,"NoSignifi"]
[605,"REACTOME_TRISTETRAPROLIN_TTP_ZFP36_BINDS_AND_DESTABILIZES_MRNA",0.969938070426516,0.00645268732396526,0.354330572219108,0.332095252909812,-0.305506516291555,-7.20188039035839,"NoSignifi"]
[606,"REACTOME_CROSSLINKING_OF_COLLAGEN_FIBRILS",0.98133813400727,0.0052273383382381,0.348803316329975,0.326444129385746,0.13994857292692,-7.19078168889518,"NoSignifi"]
[607,"REACTOME_ERYTHROCYTES_TAKE_UP_CARBON_DIOXIDE_AND_RELEASE_OXYGEN",0.99689396165558,0.00637212601079246,0.340918145544625,0.318834379031613,0.0430381290930658,-7.17542789754448,"NoSignifi"]
[608,"REACTOME_CONDENSATION_OF_PROPHASE_CHROMOSOMES",1.00975904651708,0.00724713119039219,0.334403997363771,0.31262937810223,-0.211160507382409,-7.16254750008135,"NoSignifi"]
[609,"PID_CDC42_REG_PATHWAY",1.02275969071025,0.00532108092940523,0.328139160500224,0.306440349616943,-0.169502825159814,-7.14936363067272,"NoSignifi"]
[610,"BIOCARTA_SALMONELLA_PATHWAY",1.02767717694934,0.0142927824741596,0.326008552645183,0.304120663989181,-0.173310041181555,-7.14433288442838,"NoSignifi"]
[611,"WP_FBXL10_ENHANCEMENT_OF_MAPERK_SIGNALING_IN_DIFFUSE_LARGE_BCELL_LYMPHOMA",1.02834633658117,0.00749079798776137,0.325788972251222,0.303805910695809,-0.283707435534137,-7.14364644775784,"NoSignifi"]
[612,"REACTOME_TELOMERE_EXTENSION_BY_TELOMERASE",1.03833425683648,0.00524845645085714,0.320894689030284,0.299133611940174,-0.146886132582577,-7.13334755043534,"NoSignifi"]
[613,"REACTOME_ACTIVATED_NTRK3_SIGNALS_THROUGH_RAS",1.0406013788495,0.00907743962504637,0.319879964187761,0.298079777694533,-0.218929602110306,-7.13099598094224,"NoSignifi"]
[614,"REACTOME_SMALL_INTERFERING_RNA_SIRNA_BIOGENESIS",1.06672929197188,0.00771256742292736,0.307149986805842,0.286113736022581,-0.340347759150812,-7.10352473864406,"NoSignifi"]
[615,"REACTOME_ACTIVATION_OF_GENE_EXPRESSION_BY_SREBF_SREBP",1.06771397226827,0.00544643060004635,0.30678389154935,0.285669210754455,-0.271905323401861,-7.10247611462164,"NoSignifi"]
[616,"REACTOME_TRAFFICKING_OF_GLUR2_CONTAINING_AMPA_RECEPTORS",1.07363550199359,0.00620073903231573,0.30414405366582,0.283005836710638,-0.0447647674327561,-7.09614964890261,"NoSignifi"]
[617,"REACTOME_EXPORT_OF_VIRAL_RIBONUCLEOPROTEINS_FROM_NUCLEUS",1.08721251120028,0.00539470063028802,0.297757707072074,0.27696288744862,-0.30812070841544,-7.08151213466333,"NoSignifi"]
[618,"BIOCARTA_STATHMIN_PATHWAY",1.08920804304473,0.00647874007027494,0.296918560743745,0.276082170516113,-0.0665733920496605,-7.07934522942453,"NoSignifi"]
[619,"WP_15Q112_COPY_NUMBER_VARIATION_SYNDROME",1.09345505655967,0.00816428110482026,0.295016591122701,0.274214139184562,-0.285713536144023,-7.07472026324475,"NoSignifi"]
[620,"BIOCARTA_ARENRF2_PATHWAY",1.097150045662,0.00751458301227986,0.293382138047101,0.272595954177367,-0.220385617916012,-7.07068180887019,"NoSignifi"]
[621,"WP_MIR124_PREDICTED_INTERACTIONS_WITH_CELL_CYCLE_AND_DIFFERENTIATION",1.09856228485495,0.0109033608136039,0.292824689344384,0.271979207073242,-0.265227685740865,-7.06913469799524,"NoSignifi"]
[622,"WP_HOSTPATHOGEN_INTERACTION_OF_HUMAN_CORONAVIRUSES_MAPK_SIGNALING",1.10393446809142,0.00638122527761628,0.290519216958102,0.269641823836619,-0.235168750561294,-7.06323127932454,"NoSignifi"]
[623,"REACTOME_COBALAMIN_CBL_VITAMIN_B12_TRANSPORT_AND_METABOLISM",1.1372172056207,0.00709640722645286,0.275649061780295,0.255468276892871,-0.110585662211381,-7.02601556618447,"NoSignifi"]
[624,"REACTOME_INTRAFLAGELLAR_TRANSPORT",1.14012424688398,0.00580760969201678,0.274440242847144,0.254255366686322,-0.121749260647342,-7.02271252448918,"NoSignifi"]
[625,"REACTOME_METABOLISM_OF_COFACTORS",1.14086592261488,0.00720844873425813,0.274206775893325,0.253946558646146,-0.163841603478145,-7.02186846695101,"NoSignifi"]
[626,"REACTOME_NECTIN_NECL_TRANS_HETERODIMERIZATION",1.14377544747451,0.0109211924604998,0.273000878016695,0.252737654952028,-0.0638257759858113,-7.01855200865073,"NoSignifi"]
[627,"REACTOME_METABOLISM_OF_NITRIC_OXIDE_NOS3_ACTIVATION_AND_REGULATION",1.15038950392539,0.00908982300163369,0.270344115666692,0.250004460540621,-0.210008472964223,-7.01098147301493,"NoSignifi"]
[628,"BIOCARTA_RELA_PATHWAY",1.15684853570256,0.00766426070345161,0.267674763403235,0.247355322861492,-0.249813011484247,-7.00354626033665,"NoSignifi"]
[629,"REACTOME_FATTY_ACYL_COA_BIOSYNTHESIS",1.15988619455103,0.00558290629402339,0.266431192496275,0.246116263513766,-0.152166767630101,-7.00003511736629,"NoSignifi"]
[630,"REACTOME_LEUKOTRIENE_RECEPTORS",1.17593447038862,0.012976444498806,0.25951776087934,0.239642412795801,-0.12034481560653,-6.98133258802105,"NoSignifi"]
[631,"BIOCARTA_GH_PATHWAY",1.17641757920178,0.00642107005197373,0.259403524250709,0.239449407000654,-0.228555126441452,-6.98076559318232,"NoSignifi"]
[632,"REACTOME_LYSOSPHINGOLIPID_AND_LPA_RECEPTORS",1.1820216724549,0.00653929257983446,0.257146333043309,0.237218536784971,0.0630970776111832,-6.97417140044422,"NoSignifi"]
[633,"REACTOME_INWARDLY_RECTIFYING_K_CHANNELS",1.19037340532627,0.00560603756851749,0.253692817797924,0.233921211552539,0.148907677084903,-6.96428599126884,"NoSignifi"]
[634,"REACTOME_GOLGI_CISTERNAE_PERICENTRIOLAR_STACK_REORGANIZATION",1.1921811859734,0.00953579561091297,0.25301600581029,0.233211784032966,-0.220667992953238,-6.9621370762861,"NoSignifi"]
[635,"WP_CEREBRAL_ORGANIC_ACIDURIAS_INCLUDING_DISEASES",1.19774434359861,0.0119193046978728,0.250749636434039,0.231038210897895,-0.176008176890228,-6.95550367787511,"NoSignifi"]
[636,"REACTOME_METAL_SEQUESTRATION_BY_ANTIMICROBIAL_PROTEINS",1.21078267932128,0.0151335623848195,0.245461914869981,0.226000528232179,-0.0134255170504997,-6.93983604849829,"NoSignifi"]
[637,"WP_TRANSSULFURATION_PATHWAY",1.21189883514276,0.00866849586451282,0.245087320805392,0.225572945734518,-0.247440328918148,-6.93848692969587,"NoSignifi"]
[638,"PID_TCR_JNK_PATHWAY",1.21565455670523,0.00778891398335874,0.243618005603951,0.224138428232785,-0.167205080034175,-6.93393819064869,"NoSignifi"]
[639,"BIOCARTA_TOLL_PATHWAY",1.22557319231555,0.0074799191651278,0.239710202465697,0.220381343359994,-0.260689849792051,-6.92185759008324,"NoSignifi"]
[640,"REACTOME_PTK6_REGULATES_RTKS_AND_THEIR_EFFECTORS_AKT1_AND_DOK1",1.23097827089353,0.0118969565446443,0.237591226939169,0.218353070911706,-0.180003469616142,-6.91523305280689,"NoSignifi"]
[641,"PID_WNT_SIGNALING_PATHWAY",1.23229508362228,0.00552128564941591,0.2371428276223,0.217860971530203,-0.0169376152767564,-6.91361473422601,"NoSignifi"]
[642,"REACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS",1.24674607765831,0.0056734189981216,0.231406392601731,0.21251288821252,-0.131548104280113,-6.89574129176538,"NoSignifi"]
[643,"REACTOME_TRIGLYCERIDE_METABOLISM",1.24870766598149,0.00637209347219463,0.230708685631634,0.211794309582887,-0.103039005476238,-6.89329907919038,"NoSignifi"]
[644,"BIOCARTA_AKAP95_PATHWAY",1.25065377457373,0.0105207361718861,0.23001853791528,0.211083138707679,-0.16480852649302,-6.89087234591833,"NoSignifi"]
[645,"REACTOME_NOTCH3_INTRACELLULAR_DOMAIN_REGULATES_TRANSCRIPTION",1.26855945452102,0.00681169223950015,0.223058445499058,0.204620753479062,-0.209473586926997,-6.86836725219557,"NoSignifi"]
[646,"BIOCARTA_PLC_PATHWAY",1.27152116128305,0.00996603218526836,0.221990140111096,0.203565857227381,-0.0939181444318407,-6.86461394800299,"NoSignifi"]
[647,"REACTOME_REGULATION_OF_TP53_EXPRESSION_AND_DEGRADATION",1.2734844229934,0.006639223084728,0.221311386819564,0.202868771251267,-0.218089894759402,-6.86212112791845,"NoSignifi"]
[648,"REACTOME_DAG_AND_IP3_SIGNALING",1.27512943082331,0.00504101292167682,0.220756915463255,0.202286026450136,-0.0831382613750095,-6.86002944497256,"NoSignifi"]
[649,"REACTOME_REGULATION_OF_PYRUVATE_DEHYDROGENASE_PDH_COMPLEX",1.28477153282055,0.00848293555787216,0.217216017436672,0.198894828381622,-0.231968623231749,-6.84771490330719,"NoSignifi"]
[650,"WP_AUTOPHAGY",1.28865030408527,0.0065121421300752,0.215818555351454,0.197542422627697,-0.238715430959188,-6.84273491935054,"NoSignifi"]
[651,"REACTOME_FATTY_ACID_METABOLISM",1.28909442551191,0.00356202112176618,0.215729364908065,0.197388001899687,-0.0932440286656496,-6.84216375085839,"NoSignifi"]
[652,"REACTOME_UPTAKE_AND_FUNCTION_OF_ANTHRAX_TOXINS",1.29569807874219,0.0117657295287449,0.213309963558456,0.195102331716253,-0.24770121561042,-6.833647817574,"NoSignifi"]
[653,"BIOCARTA_ERAD_PATHWAY",1.30116453837214,0.00863729026856996,0.211335391331087,0.193225003544954,-0.205338526121443,-6.82656547538394,"NoSignifi"]
[654,"WP_IL1_SIGNALING_PATHWAY",1.3120097319228,0.00593481124370898,0.207381330478562,0.18953981925318,-0.22806317370341,-6.8124262127573,"NoSignifi"]
[655,"REACTOME_REGULATION_OF_BETA_CELL_DEVELOPMENT",1.32275747473501,0.00641184744722195,0.203591993817514,0.185939111762487,-0.155567064414601,-6.79829824629229,"NoSignifi"]
[656,"WP_GLYCOSYLATION_AND_RELATED_CONGENITAL_DEFECTS",1.32462414765281,0.00699344798109791,0.202987916809489,0.185318928099351,-0.243912983627584,-6.79583274993754,"NoSignifi"]
[657,"PID_TNF_PATHWAY",1.32731834341137,0.00626464125394488,0.202159826208032,0.184426508119608,-0.235360551313906,-6.79226813487302,"NoSignifi"]
[658,"BIOCARTA_PEPI_PATHWAY",1.35440225478783,0.0189117691219257,0.19287570203046,0.175631416929896,-0.0811101842352582,-6.75603190749653,"NoSignifi"]
[659,"REACTOME_SYNTHESIS_OF_SUBSTRATES_IN_N_GLYCAN_BIOSYTHESIS",1.36873361509225,0.00469100047489782,0.187975612821069,0.171106006542255,-0.12229026817858,-6.73656159432442,"NoSignifi"]
[660,"WP_HEME_BIOSYNTHESIS",1.37387307996049,0.00986990728877357,0.186354434820451,0.169504573642353,-0.229762909830422,-6.72952930446129,"NoSignifi"]
[661,"REACTOME_ALPHA_PROTEIN_KINASE_1_SIGNALING_PATHWAY",1.38350785309446,0.0129656098440849,0.183155132511839,0.166532753751486,-0.181880641272713,-6.71627512287132,"NoSignifi"]
[662,"WP_COMPLEMENT_ACTIVATION",1.38357363473058,0.00629421756772996,0.183155132511839,0.166512599108843,0.260395562688763,-6.71618431137687,"NoSignifi"]
[663,"KEGG_BASAL_CELL_CARCINOMA",1.39163151160887,0.0052085086364417,0.180566944007173,0.164057618154965,-0.0451079323562438,-6.70502777060882,"NoSignifi"]
[664,"BIOCARTA_LECTIN_PATHWAY",1.39714685237349,0.00495130753440876,0.178867714886026,0.162393056935997,0.436358256096499,-6.6973541634571,"NoSignifi"]
[665,"WP_MITOCHONDRIAL_GENE_EXPRESSION",1.40699175538223,0.00753869464048673,0.175760609276541,0.159453535203987,-0.184278219225341,-6.68358132618039,"NoSignifi"]
[666,"BIOCARTA_VITCB_PATHWAY",1.41793042133793,0.01173228304819,0.172276813815063,0.156234843297871,-0.0238567447018842,-6.6681649473075,"NoSignifi"]
[667,"REACTOME_RESOLUTION_OF_AP_SITES_VIA_THE_MULTIPLE_NUCLEOTIDE_PATCH_REPLACEMENT_PATHWAY",1.43338880955236,0.00817224715093787,0.167478798099447,0.151770597737893,-0.198308984856129,-6.64617519509218,"NoSignifi"]
[668,"REACTOME_TRANSCRIPTIONAL_REGULATION_BY_MECP2",1.44478519955549,0.00558584014203745,0.163977228763484,0.148542125246273,-0.20941369000473,-6.62981104865399,"NoSignifi"]
[669,"WP_ENDOTHELIN_PATHWAYS",1.46574452354975,0.00832520881766667,0.157809372356951,0.142741878302627,-0.0947027675232283,-6.59937720813417,"NoSignifi"]
[670,"REACTOME_MULTIFUNCTIONAL_ANION_EXCHANGERS",1.46600010313476,0.00919483173548435,0.15779123672143,0.142672238331118,0.382311752764589,-6.59900339141098,"NoSignifi"]
[671,"REACTOME_DEFECTS_OF_CONTACT_ACTIVATION_SYSTEM_CAS_AND_KALLIKREIN_KININ_SYSTEM_KKS",1.53276373236705,0.0118945841846518,0.138953522902177,0.125358205209319,-0.139550780450988,-6.49912183693651,"NoSignifi"]
[672,"WP_NANOMATERIAL_INDUCED_APOPTOSIS",1.54113163085388,0.00949358241735501,0.136733083649034,0.123308884140981,-0.218969624057823,-6.48628952744665,"NoSignifi"]
[673,"REACTOME_ACTIVATED_NTRK2_SIGNALS_THROUGH_PI3K",1.54128206840481,0.0147142656002239,0.136733083649034,0.123272282416632,-0.248886345178808,-6.48605818991895,"NoSignifi"]
[674,"REACTOME_LIPOPHAGY",1.54237055973146,0.0133333722602619,0.136501247649662,0.123007703263241,-0.153465712112137,-6.48438367405515,"NoSignifi"]
[675,"REACTOME_GLYCOGEN_STORAGE_DISEASES",1.54390410209657,0.014965535820425,0.136139404807805,0.122635698662901,-0.121978493716378,-6.48202249423919,"NoSignifi"]
[676,"WP_MELATONIN_METABOLISM_AND_EFFECTS",1.54860197854486,0.00721727425590241,0.134930923726113,0.121501563908568,-0.186784868200549,-6.47477462175725,"NoSignifi"]
[677,"REACTOME_INSULIN_RECEPTOR_RECYCLING",1.55464578996395,0.0105744193322061,0.133373985751046,0.120054586364302,-0.150903078570677,-6.46541786810815,"NoSignifi"]
[678,"WP_CONSTITUTIVE_ANDROSTANE_RECEPTOR_PATHWAY",1.58184388194841,0.00839856447012358,0.126466965813875,0.113709333297563,-0.142724679315661,-6.42286014232821,"NoSignifi"]
[679,"REACTOME_RECOGNITION_OF_DNA_DAMAGE_BY_PCNA_CONTAINING_REPLICATION_COMPLEX",1.59684504043039,0.0105795204980454,0.122794358147621,0.110324350791874,-0.187459119955756,-6.39907166014772,"NoSignifi"]
[680,"WP_MIR517_RELATIONSHIP_WITH_ARCN1_AND_USP1",1.60640174952734,0.0182456726813696,0.120485983339757,0.108209746170861,-0.318549911927226,-6.38379981991325,"NoSignifi"]
[681,"REACTOME_MUSCARINIC_ACETYLCHOLINE_RECEPTORS",1.61004145577121,0.0114206661323534,0.119688635485333,0.107412877999658,0.390301793870013,-6.37795953378382,"NoSignifi"]
[682,"WP_FOLATE_METABOLISM",1.61059171183771,0.00557425825406832,0.119599809814384,0.107292811840906,-0.0877521544732627,-6.37707544113228,"NoSignifi"]
[683,"WP_VITAMIN_B12_METABOLISM",1.62102732490207,0.00634644867518511,0.117172066442945,0.105035823393692,-0.0563425970464566,-6.36025144279438,"NoSignifi"]
[684,"REACTOME_NOREPINEPHRINE_NEUROTRANSMITTER_RELEASE_CYCLE",1.62348554085229,0.00956943536042637,0.116629036536457,0.104509689959794,0.0164681907940346,-6.35627257112376,"NoSignifi"]
[685,"REACTOME_ACTIVATION_OF_THE_AP_1_FAMILY_OF_TRANSCRIPTION_FACTORS",1.62455315540419,0.014431291006837,0.11641859728528,0.104281840685701,-0.236495433861927,-6.3545426516454,"NoSignifi"]
[686,"BIOCARTA_NUCLEARRS_PATHWAY",1.63422795584133,0.00771546004605876,0.114219578926524,0.102235000975731,0.112145394319323,-6.33881416873941,"NoSignifi"]
[687,"WP_NUCLEAR_RECEPTORS_IN_LIPID_METABOLISM_AND_TOXICITY",1.63422795584133,0.00771546004605876,0.114219578926524,0.102235000975731,0.112145394319323,-6.33881416873941,"NoSignifi"]
[688,"BIOCARTA_HSP27_PATHWAY",1.64608281929157,0.0114777757679112,0.111634685366297,0.0997706752818218,-0.205832103236784,-6.31941424570979,"NoSignifi"]
[689,"REACTOME_MAP3K8_TPL2_DEPENDENT_MAPK1_3_ACTIVATION",1.64711400188447,0.0130849446313794,0.111439435547761,0.0995585780467175,-0.229878722744222,-6.31772013799748,"NoSignifi"]
[690,"REACTOME_FANCONI_ANEMIA_PATHWAY",1.6474122783155,0.0090181272297411,0.111412913218797,0.0994972946323064,-0.0921015522731711,-6.31722990831913,"NoSignifi"]
[691,"WP_KALLMANN_SYNDROME",1.64861222018375,0.0100529042024217,0.111221226177535,0.0992510604721926,-0.114303353583645,-6.31525685763281,"NoSignifi"]
[692,"WP_EICOSANOID_SYNTHESIS",1.66945432575252,0.00780428840127649,0.106635841630281,0.0950512461495282,0.0880053937974674,-6.28075733591547,"NoSignifi"]
[693,"WP_NAD_BIOSYNTHETIC_PATHWAYS",1.67857991697751,0.00877056128720502,0.104703043784191,0.0932577717915869,-0.154295223867496,-6.26551555766625,"NoSignifi"]
[694,"WP_GLYCOSAMINOGLYCAN_DEGRADATION",1.68691598867783,0.0101155090150176,0.103007479550246,0.0916432940533058,-0.193839219893737,-6.2515198690265,"NoSignifi"]
[695,"REACTOME_DISEASES_OF_METABOLISM",1.69140869573148,0.00330920409328159,0.102117433200557,0.0907825359255964,-0.0899948585612938,-6.24394818408158,"NoSignifi"]
[696,"REACTOME_ACTIVATED_NTRK2_SIGNALS_THROUGH_FRS2_AND_FRS3",1.6914534740793,0.0135020142055235,0.102117433200557,0.0907739896832915,-0.268054013495461,-6.24387261656366,"NoSignifi"]
[697,"REACTOME_CARNITINE_METABOLISM",1.70447282632249,0.0107054318057786,0.0994567037082053,0.0883164791363011,-0.0881915557587917,-6.22181646740346,"NoSignifi"]
[698,"WP_MIRNA_BIOGENESIS",1.70924712685957,0.0174177305010061,0.0984945257560702,0.0874288452308437,-0.24037764846716,-6.21368594039215,"NoSignifi"]
[699,"REACTOME_FRS_MEDIATED_FGFR1_SIGNALING",1.71183198697738,0.00979626679691979,0.0979937646993698,0.0869512824424233,-0.0776939796584026,-6.20927449610777,"NoSignifi"]
[700,"WP_VITAMIN_DSENSITIVE_CALCIUM_SIGNALING_IN_DEPRESSION",1.71607049041806,0.00745534029323262,0.0971533160847348,0.0861727624786666,-0.011607726868411,-6.20202644502381,"NoSignifi"]
[701,"BIOCARTA_ACTINY_PATHWAY",1.71786779650481,0.016607274590889,0.0968198739163078,0.0858443416504916,-0.15222611824754,-6.19894755316741,"NoSignifi"]
[702,"REACTOME_HCMV_LATE_EVENTS",1.72296209782244,0.00776000566654658,0.0958126332404063,0.0849189566540308,-0.250741195295904,-6.19020320698644,"NoSignifi"]
[703,"PID_HES_HEY_PATHWAY",1.72368151738102,0.00820281556174574,0.0957023521194389,0.0847889260005555,-0.238620436116866,-6.1889662408829,"NoSignifi"]
[704,"WP_BONE_MORPHOGENIC_PROTEIN_BMP_SIGNALING_AND_REGULATION",1.72763081277977,0.0114722388856593,0.0949722322571575,0.084077981593381,-0.231378242888245,-6.18216664982942,"NoSignifi"]
[705,"REACTOME_RAS_ACTIVATION_UPON_CA2_INFLUX_THROUGH_NMDA_RECEPTOR",1.73189410494402,0.0089347377413136,0.0941473260464946,0.0833159366464087,-0.00623032290205203,-6.1748089850084,"NoSignifi"]
[706,"REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS",1.73496338480194,0.0066204373664332,0.0935669777101098,0.0827707879743279,0.418572896194599,-6.16950074564163,"NoSignifi"]
[707,"REACTOME_STAT5_ACTIVATION",1.74654328054295,0.0167343952419253,0.0913061367711028,0.0807400082581176,-0.20666470504638,-6.14938903304524,"NoSignifi"]
[708,"REACTOME_ANTIMICROBIAL_PEPTIDES",1.75079323777748,0.0121301184616893,0.0905439364792819,0.0800049155328068,0.0340823502890381,-6.14197425353691,"NoSignifi"]
[709,"BIOCARTA_SRCRPTP_PATHWAY",1.75213905112706,0.0116830471868499,0.0903162663994777,0.0797732744378652,-0.111597223180944,-6.1396224961983,"NoSignifi"]
[710,"REACTOME_ATTACHMENT_OF_GPI_ANCHOR_TO_UPAR",1.75597707624767,0.0151614406602115,0.0896059757350619,0.0791156675096683,-0.268875111798535,-6.13290577369555,"NoSignifi"]
[711,"REACTOME_PYRIMIDINE_CATABOLISM",1.76586405827949,0.0149834056030208,0.0877438336201295,0.0774419260291021,-0.120420418742848,-6.11553543297251,"NoSignifi"]
[712,"REACTOME_APC_CDC20_MEDIATED_DEGRADATION_OF_NEK2A",1.76691976218205,0.0111575033953195,0.0875767652241642,0.0772649261340045,-0.189009194520482,-6.1136749170926,"NoSignifi"]
[713,"PID_P38_GAMMA_DELTA_PATHWAY",1.7770262695891,0.0148933052688583,0.0857077843237532,0.0755870945419335,-0.159084640416584,-6.09580750173773,"NoSignifi"]
[714,"KEGG_STEROID_BIOSYNTHESIS",1.80501892342441,0.0123960137038238,0.080644679437386,0.0710946516092745,-0.208720584808223,-6.04578718798958,"NoSignifi"]
[715,"REACTOME_CYTOSOLIC_IRON_SULFUR_CLUSTER_ASSEMBLY",1.80671662615995,0.0119669223614618,0.0803745440227129,0.0708293889970736,-0.154054639820505,-6.04272841600345,"NoSignifi"]
[716,"REACTOME_CALCITONIN_LIKE_LIGAND_RECEPTORS",1.81908045726331,0.0144045814787876,0.0782699888323355,0.0689219537288784,0.0444790960219696,-6.0203656651568,"NoSignifi"]
[717,"WP_PHYSIOLOGICAL_AND_PATHOLOGICAL_HYPERTROPHY_OF_THE_HEART",1.83028604126772,0.0128009197702703,0.0764069474393332,0.0672298646834619,-0.188501457384698,-5.99996617936158,"NoSignifi"]
[718,"REACTOME_IRAK1_RECRUITS_IKK_COMPLEX",1.83353398540561,0.0161492629127837,0.0758859647927483,0.0667458536486825,-0.180077929468686,-5.9940299721635,"NoSignifi"]
[719,"REACTOME_SIGNALING_BY_FGFR4",1.83653846611685,0.00966642994907843,0.0754087575987268,0.0663006822882193,-0.163689861509497,-5.98852937240321,"NoSignifi"]
[720,"REACTOME_TRANSPORT_OF_NUCLEOSIDES_AND_FREE_PURINE_AND_PYRIMIDINE_BASES_ACROSS_THE_PLASMA_MEMBRANE",1.85143952647548,0.014644613486391,0.0729945500136968,0.0641288151942194,-0.10931443452094,-5.9611154999717,"NoSignifi"]
[721,"REACTOME_SUMOYLATION_OF_UBIQUITINYLATION_PROTEINS",1.86316139794631,0.00827430600690965,0.0711518373562861,0.0624619031042701,-0.304397340918072,-5.93939487205026,"NoSignifi"]
[722,"REACTOME_LOSS_OF_FUNCTION_OF_MECP2_IN_RETT_SYNDROME",1.87047025698747,0.0131737841177273,0.0700155867060249,0.0614408033138903,-0.253183961151118,-5.92578220759528,"NoSignifi"]
[723,"REACTOME_TRANSMISSION_ACROSS_CHEMICAL_SYNAPSES",1.87407465383623,0.00378244456448313,0.0694742851102448,0.0609423553598639,0.0145492859468304,-5.91904944886512,"NoSignifi"]
[724,"KEGG_MATURITY_ONSET_DIABETES_OF_THE_YOUNG",1.88464992210695,0.0099478798556516,0.0678813218900102,0.0594992153408389,0.357512561815318,-5.89922083205658,"NoSignifi"]
[725,"WP_SARSCOV2_AND_COVID19_PATHWAY",1.89330767175433,0.0143122821324278,0.0665832431378904,0.0583389616832326,-0.0291380355030132,-5.88290454177384,"NoSignifi"]
[726,"REACTOME_SIGNALING_BY_HIPPO",1.90102490011019,0.0128644348084826,0.0654714534158556,0.0573206550655011,-0.260734909368831,-5.86829774328444,"NoSignifi"]
[727,"WP_COHESIN_COMPLEX_CORNELIA_DE_LANGE_SYNDROME",1.90184024841931,0.0104332872216709,0.0653747526279754,0.0572139366791391,-0.207581063839042,-5.86675102273309,"NoSignifi"]
[728,"WP_MAP3K1_ROLE_IN_PROMOTING_AND_BLOCKING_GONADAL_DETERMINATION",1.90915107747296,0.0147719541612089,0.0643393949998134,0.056264410202266,-0.227689995945534,-5.85285271796289,"NoSignifi"]
[729,"BIOCARTA_P27_PATHWAY",1.9129783790333,0.0161359035491086,0.0638262245709559,0.0557725781507341,-0.224293018795408,-5.84555554548078,"NoSignifi"]
[730,"REACTOME_PROCESSING_OF_DNA_DOUBLE_STRAND_BREAK_ENDS",1.91635734798403,0.00790951835194406,0.0633816602290514,0.0553413416574848,-0.176385980732016,-5.83910102885193,"NoSignifi"]
[731,"REACTOME_EFFECTS_OF_PIP2_HYDROLYSIS",1.92163776787819,0.00952427916050683,0.0626404248802396,0.0546730024174021,-0.0344099862696621,-5.82899155846084,"NoSignifi"]
[732,"WP_BIOMARKERS_FOR_PYRIMIDINE_METABOLISM_DISORDERS",1.92762883929705,0.0116169219098662,0.0618048817912597,0.0539228826964229,-0.14896067842406,-5.81748786505618,"NoSignifi"]
[733,"REACTOME_ACTIVATION_OF_CASPASES_THROUGH_APOPTOSOME_MEDIATED_CLEAVAGE",1.95255956631208,0.0200069700188893,0.0583999275336477,0.0508930542575614,-0.268371486857045,-5.7692330585151,"NoSignifi"]
[734,"REACTOME_SMAC_XIAP_REGULATED_APOPTOTIC_RESPONSE",1.95255956631208,0.0200069700188893,0.0583999275336477,0.0508930542575614,-0.268371486857045,-5.7692330585151,"NoSignifi"]
[735,"REACTOME_ACETYLCHOLINE_REGULATES_INSULIN_SECRETION",1.95448044411596,0.0144360697946352,0.058184029346219,0.0506656476864343,-0.0213669766732779,-5.76548937877294,"NoSignifi"]
[736,"REACTOME_MISCELLANEOUS_TRANSPORT_AND_BINDING_EVENTS",1.95809549495219,0.010535985994556,0.0577399405255488,0.0502399819889981,-0.232405493168434,-5.75843387672967,"NoSignifi"]
[737,"REACTOME_INTERLEUKIN_17_SIGNALING",1.95938566136148,0.00888410599569306,0.0575885135758427,0.0500887948712964,-0.23919349472454,-5.75591270132743,"NoSignifi"]
[738,"REACTOME_INITIATION_OF_NUCLEAR_ENVELOPE_NE_REFORMATION",1.9610256416779,0.0135498237104811,0.0573904538665318,0.0498971658616911,-0.196307760230529,-5.75270554232135,"NoSignifi"]
[739,"REACTOME_BETA_DEFENSINS",1.96537570513828,0.0203037008020514,0.0568312989138038,0.0493918441302155,0.0562445251048898,-5.74418553207827,"NoSignifi"]
[740,"BIOCARTA_PPARG_PATHWAY",1.97163043076122,0.0165996671033752,0.0560257003132759,0.0486727996986118,-0.239937396745366,-5.7319019934198,"NoSignifi"]
[741,"NABA_COLLAGENS",1.9841536854741,0.0103976802704718,0.0544200582963685,0.0472595243100042,0.0671575384437409,-5.70719057308878,"NoSignifi"]
[742,"REACTOME_COLLAGEN_CHAIN_TRIMERIZATION",1.9841536854741,0.0103976802704718,0.0544200582963685,0.0472595243100042,0.0671575384437409,-5.70719057308878,"NoSignifi"]
[743,"PID_IL5_PATHWAY",1.98662881746416,0.0145517734850852,0.0541452328754508,0.0469843248838257,-0.200964275523228,-5.70228803033699,"NoSignifi"]
[744,"REACTOME_SYNTHESIS_OF_12_EICOSATETRAENOIC_ACID_DERIVATIVES",1.9927252829875,0.0205455238742342,0.0534122376127784,0.0463122303187721,-0.0334200104903501,-5.69018658984149,"NoSignifi"]
[745,"REACTOME_RECEPTOR_MEDIATED_MITOPHAGY",2.0043883296726,0.0162905007954664,0.0519755731073458,0.0450490038167244,-0.221951847478984,-5.66693226729568,"Up"]
[746,"REACTOME_G2_M_DNA_DAMAGE_CHECKPOINT",2.00825751582156,0.00846097710424112,0.0515396566386323,0.0446364030335254,-0.189449892802273,-5.65918774544428,"Up"]
[747,"BIOCARTA_CHREBP_PATHWAY",2.00911648552481,0.0121066303421484,0.0514544373857727,0.0445452383036075,-0.105409335816233,-5.65746641618793,"Up"]
[748,"REACTOME_TRANSCRIPTIONAL_REGULATION_OF_PLURIPOTENT_STEM_CELLS",2.02445262222088,0.0106652899051881,0.0496627075842542,0.0429438325028486,-0.0444080736861698,-5.62660980494492,"Up"]
[749,"REACTOME_FORMATION_OF_SENESCENCE_ASSOCIATED_HETEROCHROMATIN_FOCI_SAHF",2.03546299606707,0.0154361495692246,0.0483869802048173,0.0418243735778481,-0.225181374288809,-5.60431210533355,"Up"]
[750,"REACTOME_RECEPTOR_TYPE_TYROSINE_PROTEIN_PHOSPHATASES",2.03727490766837,0.01126025371775,0.0481954256822349,0.0416425388570187,0.0515853900162484,-5.60063112419559,"Up"]
[751,"REACTOME_MITOTIC_TELOPHASE_CYTOKINESIS",2.0448789790807,0.01570733947534,0.0473576466911957,0.0408867131858198,-0.214508865041269,-5.58514741358453,"Up"]
[752,"KEGG_GLUTATHIONE_METABOLISM",2.05057544223959,0.0097583165237192,0.0467289374351706,0.0403281450604475,-0.153500267229461,-5.5735102812137,"Up"]
[753,"REACTOME_DNA_METHYLATION",2.06101378470882,0.0193595989912307,0.0455802213485839,0.0393213987814875,-0.125178552618201,-5.55210215057674,"Up"]
[754,"WP_SARSCOV2_B117_VARIANT_ANTAGONISES_INNATE_IMMUNE_ACTIVATION",2.07185852424827,0.0153473909141649,0.0444114594320478,0.0382981411296606,-0.270531815408803,-5.52974547920691,"Up"]
[755,"REACTOME_NRCAM_INTERACTIONS",2.07371913758032,0.0172013705234926,0.0442278425340325,0.0381248777579127,-0.0250914936349073,-5.52589799946204,"Up"]
[756,"BIOCARTA_DSP_PATHWAY",2.07538102226124,0.0177078239302772,0.0440662131952952,0.0379706843794817,-0.176674257695553,-5.52245854376893,"Up"]
[757,"REACTOME_DIGESTION_OF_DIETARY_LIPID",2.0768802526216,0.0234046530771505,0.0439225069417785,0.037832037861795,0.139427182683805,-5.51935335691054,"Up"]
[758,"REACTOME_DNA_DOUBLE_STRAND_BREAK_REPAIR",2.08744533092399,0.00624041384367013,0.0428526463075847,0.0368671552241366,-0.148318864267755,-5.4974075647366,"Up"]
[759,"KEGG_RENIN_ANGIOTENSIN_SYSTEM",2.11428235278393,0.0106954949750427,0.0401442652678928,0.0345099824232762,0.249342634691281,-5.44116132594513,"Up"]
[760,"REACTOME_NUCLEAR_IMPORT_OF_REV_PROTEIN",2.12029067396142,0.0108173778538505,0.0395979510421539,0.0340002649805269,-0.295645564762148,-5.42847044592676,"Up"]
[761,"REACTOME_NEF_AND_SIGNAL_TRANSDUCTION",2.12602827572668,0.0158873801617684,0.0390534218166598,0.0335195361341371,0.190471000726142,-5.41631779122228,"Up"]
[762,"REACTOME_SYNTHESIS_OF_15_EICOSATETRAENOIC_ACID_DERIVATIVES",2.12982391737339,0.02163789958435,0.0387018460921821,0.0332047215291562,-0.0982964705051491,-5.40826031166382,"Up"]
[763,"REACTOME_PTK6_EXPRESSION",2.13438888445217,0.0230495345636182,0.038294568930395,0.0328294533239317,-0.294870661236021,-5.39855066554924,"Up"]
[764,"REACTOME_SIGNALING_BY_MST1",2.14244055873883,0.0313078890497783,0.0375623735731846,0.0321764057025356,-0.178375708553818,-5.38137418756356,"Up"]
[765,"WP_OLIGODENDROCYTE_SPECIFICATION_AND_DIFFERENTIATION_LEADING_TO_MYELIN_COMPONENTS_FOR_CNS",2.14868148153492,0.0120553106550717,0.037009590412058,0.0316779119012791,0.0615051159594172,-5.36801608885345,"Up"]
[766,"REACTOME_DOWNSTREAM_SIGNALING_OF_ACTIVATED_FGFR1",2.15226383570183,0.0105723412046047,0.0366932617810302,0.0313947745872782,-0.149746769462354,-5.36033086162136,"Up"]
[767,"WP_KISSPEPTINKISSPEPTIN_RECEPTOR_SYSTEM_IN_THE_OVARY",2.15543317199151,0.00928714041466884,0.0364169711687616,0.0311460937627567,-0.12044802920444,-5.35352101606958,"Up"]
[768,"REACTOME_CLASS_I_PEROXISOMAL_MEMBRANE_PROTEIN_IMPORT",2.1554564630634,0.0120264186656079,0.0364169711687616,0.0311442725132277,-0.246066791809139,-5.35347093426803,"Up"]
[769,"REACTOME_TELOMERE_C_STRAND_LAGGING_STRAND_SYNTHESIS",2.16321731889393,0.0105874123361993,0.0357394022604151,0.0305424783824667,-0.182912300051339,-5.33675298433642,"Up"]
[770,"WP_SOMATIC_SEX_DETERMINATION",2.1738948662491,0.0158437541462867,0.034830936538811,0.0297308601360297,0.185327372430468,-5.31365394906264,"Up"]
[771,"REACTOME_SIGNALING_BY_MEMBRANE_TETHERED_FUSIONS_OF_PDGFRA_OR_PDGFRB",2.17621484401846,0.022457684053537,0.0346409306794445,0.029556988423858,-0.131015551711267,-5.30862004681603,"Up"]
[772,"REACTOME_ACTIVATION_OF_NIMA_KINASES_NEK9_NEK6_NEK7",2.18273253238995,0.0160114926450993,0.0341008849990114,0.0290731904158238,-0.045276722955069,-5.29444921566536,"Up"]
[773,"REACTOME_RHOBTB3_ATPASE_CYCLE",2.18680961262496,0.0169579900538001,0.0337633551076457,0.0287740334014551,-0.223898793659165,-5.28556325207559,"Up"]
[774,"REACTOME_MASTL_FACILITATES_MITOTIC_PROGRESSION",2.1868408751525,0.0209401136205656,0.0337633551076457,0.0287717497834289,-0.231673730013578,-5.2854950516319,"Up"]
[775,"REACTOME_CYCLIN_A_B1_B2_ASSOCIATED_EVENTS_DURING_G2_M_TRANSITION",2.1891084304445,0.0108407723740147,0.0335934035041593,0.0286065284900466,-0.151067546721947,-5.28054569165829,"Up"]
[776,"REACTOME_DISEASES_ASSOCIATED_WITH_GLYCOSYLATION_PRECURSOR_BIOSYNTHESIS",2.19316303195921,0.01286006272439,0.033262040816718,0.0283131339340687,-0.26480993195545,-5.27168299531819,"Up"]
[777,"BIOCARTA_VEGF_PATHWAY",2.20562339242782,0.0129671032387265,0.0322601572108875,0.0274276640254509,-0.206153488010756,-5.24434411694844,"Up"]
[778,"REACTOME_SCAVENGING_BY_CLASS_F_RECEPTORS",2.20590805827496,0.0264169145533109,0.0322494933597536,0.0274077171974424,-0.139083147196049,-5.24371773241511,"Up"]
[779,"REACTOME_GABA_RECEPTOR_ACTIVATION",2.20621102011076,0.00929113786241694,0.0322373281286448,0.0273865021011902,0.0593466992790449,-5.24305100028221,"Up"]
[780,"REACTOME_SYNTHESIS_OF_PIPS_AT_THE_GOLGI_MEMBRANE",2.21034245840798,0.0145842411924402,0.0319111124426871,0.0270986066188406,-0.199710032591121,-5.23394975797557,"Up"]
[781,"WP_TNFALPHA_SIGNALING_PATHWAY",2.22473134407476,0.00904582575561272,0.030766498490451,0.0261162315121372,-0.205129456053551,-5.2021193236989,"Up"]
[782,"WP_PHOTODYNAMIC_THERAPYINDUCED_UNFOLDED_PROTEIN_RESPONSE",2.22807094422143,0.0147206930087098,0.0305152686687302,0.0258926790492094,-0.190909010006713,-5.19470210423581,"Up"]
[783,"REACTOME_SIGNALING_BY_FGFR3",2.23473496833732,0.0122995442508848,0.0300311863100548,0.0254515317175633,-0.185250236671752,-5.17986814554055,"Up"]
[784,"PID_RAC1_REG_PATHWAY",2.23621402104342,0.00904875093984096,0.0299286183065053,0.0253545076139119,-0.0753876386528339,-5.17656980670924,"Up"]
[785,"REACTOME_EGR2_AND_SOX10_MEDIATED_INITIATION_OF_SCHWANN_CELL_MYELINATION",2.23840274635635,0.0118469906486045,0.02977168808323,0.0252115172364735,-0.208915942242276,-5.17168487230153,"Up"]
[786,"WP_PARKINSONS_DISEASE_PATHWAY",2.24082153582127,0.0112402483222434,0.0295978367581896,0.0250543091856605,-0.184830920180639,-5.1662809118085,"Up"]
[787,"REACTOME_REGULATION_OF_MECP2_EXPRESSION_AND_ACTIVITY",2.24456910275849,0.0113791863573142,0.0293237623381208,0.0248124142861022,-0.270957432038905,-5.15789673360527,"Up"]
[788,"WP_NEURODEGENERATION_WITH_BRAIN_IRON_ACCUMULATION_NBIA_SUBTYPES_PATHWAY",2.25494841749329,0.00980246271058191,0.0285558294947795,0.0241529907366438,-0.245282975471813,-5.13460271572612,"Up"]
[789,"PID_PLK1_PATHWAY",2.25648494601776,0.0108680931580028,0.0284533048236489,0.0240566740513037,-0.0701964636132199,-5.13114520082807,"Up"]
[790,"WP_AMINO_ACID_METABOLISM_PATHWAY_EXCERPT_HISTIDINE_CATABOLISM_EXTENSION",2.2593358888485,0.0266993588002661,0.0282542512609854,0.0238788459543753,-0.167198751501488,-5.12472374101187,"Up"]
[791,"BIOCARTA_CACAM_PATHWAY",2.26072470147345,0.0203693048385096,0.0281634832953798,0.0237926323116164,-0.123244949597757,-5.1215926466814,"Up"]
[792,"REACTOME_SYNTHESIS_OF_PI",2.27452696875071,0.0228406421901706,0.0271773821667724,0.0229504006624262,-0.26833721111084,-5.0903707758736,"Up"]
[793,"WP_DNA_IRDAMAGE_AND_CELLULAR_RESPONSE_VIA_ATR",2.28529325883874,0.00793252204665479,0.0264419695139296,0.0223115269076714,-0.196572203635746,-5.06588470836658,"Up"]
[794,"WP_PILOCYTIC_ASTROCYTOMA",2.28550458655173,0.0212630650367709,0.0264378639621679,0.0222991430180228,-0.390743721619346,-5.06540292380157,"Up"]
[795,"REACTOME_SIGNALING_BY_MAPK_MUTANTS",2.29193982511279,0.0225069905945185,0.0260045480121065,0.0219248871397619,-0.211987397638798,-5.05071056115005,"Up"]
[796,"BIOCARTA_MITOCHONDRIA_PATHWAY",2.29444147127416,0.0134080304403075,0.0258440871053859,0.0217808804282234,-0.222337854906248,-5.04498788367744,"Up"]
[797,"REACTOME_POLYMERASE_SWITCHING_ON_THE_C_STRAND_OF_THE_TELOMERE",2.29451714505356,0.0125650985155744,0.0258440871053859,0.021776537142021,-0.18518258944931,-5.04481467780959,"Up"]
[798,"BIOCARTA_RARRXR_PATHWAY",2.31623196611907,0.0216674942592153,0.024435705143436,0.0205609475802056,-0.268525243392784,-4.99487691138273,"Up"]
[799,"REACTOME_ION_CHANNEL_TRANSPORT",2.34181281560799,0.00640992644711439,0.0228703427365073,0.0192052237082209,-0.0350156338408727,-4.93544545789856,"Up"]
[800,"REACTOME_MYOCLONIC_EPILEPSY_OF_LAFORA",2.3420310253968,0.0301255760871854,0.0228661682209836,0.019194003553916,-0.142394465106873,-4.93493569012825,"Up"]
[801,"REACTOME_PEROXISOMAL_PROTEIN_IMPORT",2.34253076703817,0.0101894404835155,0.0228447634756311,0.0191683288677107,-0.167150168011824,-4.93376804682933,"Up"]
[802,"BIOCARTA_CHEMICAL_PATHWAY",2.34720849103204,0.0145294821824996,0.0225691534095352,0.0189294586289151,-0.277005182634907,-4.92282650391927,"Up"]
[803,"WP_CATALYTIC_CYCLE_OF_MAMMALIAN_FLAVINCONTAINING_MONOOXYGENASES_FMOS",2.37599781272211,0.0183968392726928,0.0209005521493526,0.017515847347838,0.236489162413304,-4.85500600100289,"Up"]
[804,"PID_RETINOIC_ACID_PATHWAY",2.38361905614962,0.0121955526631655,0.0204811852467349,0.0171574841321332,-0.290199994573881,-4.83691395726135,"Up"]
[805,"REACTOME_TRANSLESION_SYNTHESIS_BY_POLK",2.39992532432421,0.0185710473254055,0.0196074092149384,0.0164122747173624,-0.223846867630025,-4.79801013316457,"Up"]
[806,"PID_ERB_GENOMIC_PATHWAY",2.40177906634186,0.0168672778170646,0.0195162479815424,0.0163293842760543,-0.281964145354871,-4.79357066263828,"Up"]
[807,"REACTOME_PURINE_RIBONUCLEOSIDE_MONOPHOSPHATE_BIOSYNTHESIS",2.41018264890814,0.0194552066220337,0.0190880322301568,0.0159582131802728,-0.233777929818064,-4.77340222393347,"Up"]
[808,"WP_VITAMIN_B12_DISORDERS",2.42468264490449,0.0163751484081322,0.0183502309406327,0.0153351963697528,-0.0999998631727058,-4.73843701949633,"Up"]
[809,"WP_AUTOSOMAL_RECESSIVE_OSTEOPETROSIS_PATHWAYS",2.4308565249727,0.0192222313692646,0.0180479495294161,0.0150764922519683,-0.199129390069037,-4.72348575923331,"Up"]
[810,"WP_NAD_METABOLISM",2.45670012047318,0.0149265810196669,0.0168145674552114,0.0140348312699706,-0.131327585428713,-4.66048811683378,"Up"]
[811,"REACTOME_DEFECTIVE_CHST6_CAUSES_MCDC1",2.46361748197031,0.00568174523504555,0.0165003883054702,0.0137670243857718,0.468341892653902,-4.64351308851409,"Up"]
[812,"PID_WNT_CANONICAL_PATHWAY",2.46386379534983,0.0145700773437842,0.0164957296592355,0.0137575721044636,-0.23850449229865,-4.64290776255395,"Up"]
[813,"KEGG_RIG_I_LIKE_RECEPTOR_SIGNALING_PATHWAY",2.46426472944908,0.0104873756723413,0.0164839645397976,0.0137421985080431,-0.223945365529865,-4.64192232007139,"Up"]
[814,"WP_HOSTPATHOGEN_INTERACTION_OF_HUMAN_CORONAVIRUSES_AUTOPHAGY",2.46720235483607,0.0149513386255892,0.0163560228365575,0.0136300190304645,-0.26222829695217,-4.63469714226934,"Up"]
[815,"PID_IL3_PATHWAY",2.47258132210828,0.0151463563248529,0.0161185742819589,0.013426707119486,-0.185884032738805,-4.62144512054686,"Up"]
[816,"REACTOME_HYALURONAN_UPTAKE_AND_DEGRADATION",2.47574739555571,0.018522837832772,0.015982895003245,0.0133082944898815,-0.150788178739263,-4.61363146731466,"Up"]
[817,"WP_GLIAL_CELL_DIFFERENTIATION",2.47977046285754,0.0246637534336709,0.0158230252573043,0.0131591623681697,-0.157068017953391,-4.60368840047861,"Up"]
[818,"WP_LNCRNAMEDIATED_MECHANISMS_OF_THERAPEUTIC_RESISTANCE",2.49062713470554,0.0207925237655086,0.0153604081437397,0.0127640638522371,-0.0779580399412617,-4.57677549220546,"Up"]
[819,"REACTOME_THROMBIN_SIGNALLING_THROUGH_PROTEINASE_ACTIVATED_RECEPTORS_PARS",2.49473675813581,0.0136558714377266,0.0151899189423177,0.0126172673535716,-0.0731221687101228,-4.56655738518212,"Up"]
[820,"REACTOME_KILLING_MECHANISMS",2.49824960567414,0.0202038532120894,0.0150463946658845,0.0124929747883744,-0.209825729046991,-4.55780975116052,"Up"]
[821,"BIOCARTA_TRKA_PATHWAY",2.51354584687946,0.0167982707878755,0.0144272643914592,0.0119643103489227,-0.217650047100618,-4.51957595485501,"Up"]
[822,"REACTOME_GENE_SILENCING_BY_RNA",2.516297848336,0.00906231697962978,0.0143209703969208,0.0118713307237633,-0.216507694262034,-4.51267242816223,"Up"]
[823,"REACTOME_LOSS_OF_MECP2_BINDING_ABILITY_TO_THE_NCOR_SMRT_COMPLEX",2.52229454269242,0.0229662020916797,0.0140849638889252,0.0116709417379218,-0.280393394540087,-4.49760329504367,"Up"]
[824,"BIOCARTA_CCR5_PATHWAY",2.52512862921523,0.017614085405869902,0.0139776263435594,0.0115772849775433,-0.137663200419941,-4.49046903044637,"Up"]
[825,"BIOCARTA_CXCR4_PATHWAY",2.52962246104635,0.0152809276722337,0.0138056045405006,0.0114301462693618,-0.209010368630254,-4.47914027068898,"Up"]
[826,"REACTOME_RUNX3_REGULATES_BCL2L11_BIM_TRANSCRIPTION",2.53847997467724,0.0256766244829816,0.013466665110595,0.011144982967709,-0.280679086088794,-4.45675193198985,"Up"]
[827,"REACTOME_REGULATION_OF_LIPID_METABOLISM_BY_PPARALPHA",2.54140644115835,0.00877326536363379,0.013359958707787,0.0110521655706794,-0.221250944677855,-4.44933778452701,"Up"]
[828,"REACTOME_RESOLUTION_OF_ABASIC_SITES_AP_SITES",2.54695660622483,0.0120963094742941,0.0131548127821994,0.0108780182622034,-0.219947016594858,-4.43525310602284,"Up"]
[829,"REACTOME_N_GLYCAN_ANTENNAE_ELONGATION",2.55299375946914,0.0156145224104283,0.0129343687513141,0.0106913641837785,-0.0849241902029903,-4.41989774192065,"Up"]
[830,"REACTOME_REGULATION_OF_TP53_ACTIVITY_THROUGH_PHOSPHORYLATION",2.55379952475614,0.00843081948821825,0.0129097613585744,0.010666668544922,-0.193465090266382,-4.4178455488215,"Up"]
[831,"KEGG_PPAR_SIGNALING_PATHWAY",2.55672828611589,0.00945551632808629,0.0128068684644818,0.0105773326589242,-0.0664827571322755,-4.4103808753334,"Up"]
[832,"BIOCARTA_GHRELIN_PATHWAY",2.58322185723503,0.0194493445972942,0.0118741290297456,0.0097989607310249,-0.0218525860064841,-4.34246708416447,"Up"]
[833,"WP_BLOOD_CLOTTING_CASCADE",2.58904698066529,0.0169916085472497,0.0116800104351622,0.00963482642171784,-0.0971869884822641,-4.32744113101257,"Up"]
[834,"REACTOME_REGULATION_OF_GENE_EXPRESSION_IN_LATE_STAGE_BRANCHING_MORPHOGENESIS_PANCREATIC_BUD_PRECURSOR_CELLS",2.58978301679121,0.0185723843079698,0.0116598503408779,0.00961426256177651,-0.248856655530704,-4.32554011387922,"Up"]
[835,"BIOCARTA_KERATINOCYTE_PATHWAY",2.58980521754031,0.0127797869896248,0.0116598503408779,0.00961364291115602,-0.19540543891708,-4.32548276590903,"Up"]
[836,"BIOCARTA_STRESS_PATHWAY",2.59226137500787,0.0152463179185549,0.0115857055363843,0.00954530800264861,-0.24864412914471,-4.319135098505,"Up"]
[837,"REACTOME_SYNTHESIS_OF_IP2_IP_AND_INS_IN_THE_CYTOSOL",2.59261151707365,0.0172315373748076,0.0115786659557377,0.00953560175369624,-0.102286688634144,-4.31822970551151,"Up"]
[838,"WP_EXRNA_MECHANISM_OF_ACTION_AND_BIOGENESIS",2.6159856554537,0.0231356811096012,0.0108289647989406,0.00890722543178719,-0.261366912634678,-4.25751287987319,"Up"]
[839,"REACTOME_INITIAL_TRIGGERING_OF_COMPLEMENT",2.61892508589146,0.0108238427422129,0.0107405540397394,0.00883088063253876,0.376063151205431,-4.24983886088243,"Up"]
[840,"REACTOME_NCAM1_INTERACTIONS",2.62438976305186,0.0117218571062709,0.0105741561655521,0.008690500816223,0.130671251659318,-4.23554925937054,"Up"]
[841,"BIOCARTA_HCMV_PATHWAY",2.62600038005829,0.0175806021330345,0.0105286010948352,0.00864950865921856,-0.30132062923953,-4.23133197475187,"Up"]
[842,"REACTOME_TRANSLESION_SYNTHESIS_BY_Y_FAMILY_DNA_POLYMERASES_BYPASSES_LESIONS_ON_DNA_TEMPLATE",2.64747866451706,0.0146264463703799,0.00989114268810426,0.00811914647778598,-0.203002525901747,-4.17484558075245,"Up"]
[843,"WP_FAMILIAL_PARTIAL_LIPODYSTROPHY_FPLD",2.64801890397491,0.0135913414531953,0.00987941923745159,0.00810619014355002,-0.148939430054772,-4.17341886260818,"Up"]
[844,"REACTOME_DEFECTIVE_RIPK1_MEDIATED_REGULATED_NECROSIS",2.64908106210356,0.0248657556794632,0.0098524906180757,0.00808077081394805,-0.284893737909451,-4.17061296179083,"Up"]
[845,"REACTOME_PCNA_DEPENDENT_LONG_PATCH_BASE_EXCISION_REPAIR",2.65993731270342,0.0161423079176042,0.00954852792554942,0.00782502507798905,-0.184863184760546,-4.14186957041046,"Up"]
[846,"REACTOME_SIGNALING_BY_NTRK2_TRKB",2.66027459274002,0.0149316388301194,0.00954290451634255,0.00781719708693648,-0.195031139195896,-4.14097469515218,"Up"]
[847,"KEGG_ONE_CARBON_POOL_BY_FOLATE",2.6726245658512,0.0132251097935274,0.00920263160815843,0.00753535320951434,-0.0940474606880006,-4.10812954921721,"Up"]
[848,"BIOCARTA_ETS_PATHWAY",2.68192023127002,0.0191949010204549,0.00895462790415001,0.00732926022114302,-0.208869223187886,-4.08330719697773,"Up"]
[849,"REACTOME_TNFR1_MEDIATED_CERAMIDE_PRODUCTION",2.68774633357611,0.0269342817472441,0.00880360925292218,0.00720268300888538,-0.140899165090091,-4.06770578249961,"Up"]
[850,"WP_ALTERED_GLYCOSYLATION_OF_MUC1_IN_TUMOR_MICROENVIRONMENT",2.69732081241788,0.0210077450002498,0.00856162508176016,0.00699892630671554,-0.173576292288504,-4.04199333356535,"Up"]
[851,"REACTOME_ACTIVATED_NTRK2_SIGNALS_THROUGH_CDK5",2.70787605824364,0.0283501560404301,0.00829762183202967,0.00678031041740077,-0.175604651404531,-4.01354117352087,"Up"]
[852,"REACTOME_REGULATION_OF_BACH1_ACTIVITY",2.71342315224432,0.0293175252417913,0.00816679862718166,0.00666789901409569,-0.162704577842932,-3.99854422737896,"Up"]
[853,"BIOCARTA_FBW7_PATHWAY",2.71868032340294,0.0241955677481127,0.00804486038001244,0.0065629124152733,-0.26993383641132,-3.9843028135213,"Up"]
[854,"WP_DUAL_HIJACK_MODEL_OF_VIF_IN_HIV_INFECTION",2.72175026276028,0.0294074857763522,0.00797385295691651,0.00650229507316707,-0.161711987298497,-3.97597376722849,"Up"]
[855,"REACTOME_CREB1_PHOSPHORYLATION_THROUGH_THE_ACTIVATION_OF_CAMKII_CAMKK_CAMKIV_CASCASDE",2.72467029289357,0.020275192409063,0.00790699216548776,0.00644510562477005,-0.133616422200397,-3.96804272666013,"Up"]
[856,"WP_TARGET_OF_RAPAMYCIN_TOR_SIGNALING",2.72869819255991,0.0133572793482911,0.00781435714122277,0.00636696103105701,-0.226063653432985,-3.95708868155884,"Up"]
[857,"REACTOME_DOPAMINE_CLEARANCE_FROM_THE_SYNAPTIC_CLEFT",2.7456666526364,0.0400270346880267,0.00742478111226625,0.00604703832827623,-0.236073624846441,-3.91076476178666,"Up"]
[858,"REACTOME_NGF_INDEPENDANT_TRKA_ACTIVATION",2.75320383245262,0.0363249499671281,0.00725908061200867,0.00590963613926347,-0.020091350945915,-3.89009624695284,"Up"]
[859,"BIOCARTA_EPONFKB_PATHWAY",2.75692900971157,0.0237105494132477,0.00717992268981721,0.00584277109576218,-0.203411409778877,-3.87986013827908,"Up"]
[860,"PID_HDAC_CLASSIII_PATHWAY",2.76024253374746,0.0173556724749913,0.00711048852345866,0.00578386903848139,-0.259847230825845,-3.87074356043151,"Up"]
[861,"KEGG_ALPHA_LINOLENIC_ACID_METABOLISM",2.76435903225251,0.0185779553212007,0.0070243592430238,0.00571143919557603,0.0997388216090472,-3.85940250493147,"Up"]
[862,"BIOCARTA_SHH_PATHWAY",2.77025976565956,0.0175940314568162,0.00690128742809597,0.0056090423125112,-0.141152353619422,-3.84311639581148,"Up"]
[863,"BIOCARTA_PYK2_PATHWAY",2.77252424162961,0.0177850127970016,0.00685917647509084,0.0055701881833818,-0.243811728364635,-3.83685719976521,"Up"]
[864,"REACTOME_METHIONINE_SALVAGE_PATHWAY",2.77373770658792,0.0244635719320018,0.00683650113491878,0.00554946752045026,-0.307351755786177,-3.83350098162791,"Up"]
[865,"REACTOME_NUCLEOTIDE_SALVAGE",2.77732329037675,0.0175292448861117,0.00676438693971964,0.00548864729757953,-0.170115351494241,-3.82357535358078,"Up"]
[866,"BIOCARTA_CDMAC_PATHWAY",2.77978180063829,0.021059215547055,0.00671621365972841,0.0054472934001306,-0.205101080762682,-3.81676229379855,"Up"]
[867,"WP_TRANSCRIPTION_COFACTORS_SKI_AND_SKIL_PROTEIN_PARTNERS",2.78088010957179,0.0149945154902237,0.00669633359514412,0.00542891013128587,-0.272949214366923,-3.8137166981487,"Up"]
[868,"WP_MONOAMINE_TRANSPORT",2.78152270041505,0.01287493644331,0.0066858814356021,0.00541818056960737,0.0411454977141658,-3.81193424532455,"Up"]
[869,"REACTOME_SUPPRESSION_OF_PHAGOSOMAL_MATURATION",2.78820151783349,0.0266426240717567,0.00655785365799886,0.00530779046070825,-0.202000802102601,-3.79338382891887,"Up"]
[870,"REACTOME_TRANSPORT_AND_SYNTHESIS_OF_PAPS",2.79012519407007,0.0218397777060816,0.00652175696947562,0.00527637422834094,-0.0646630276787703,-3.78803257533872,"Up"]
[871,"REACTOME_TNF_SIGNALING",2.79103959752063,0.0141777399188378,0.00650608482160596,0.00526149976969955,-0.190305773736288,-3.78548760899001,"Up"]
[872,"REACTOME_REGULATION_OF_LOCALIZATION_OF_FOXO_TRANSCRIPTION_FACTORS",2.81822458746587,0.0272293527651822,0.00599021756816319,0.00483623166012636,-0.21157140717858,-3.70944591205433,"Up"]
[873,"REACTOME_VIRAL_MESSENGER_RNA_SYNTHESIS",2.82189785895564,0.0134966747379536,0.00592455413775631,0.00478121912871562,-0.282458148752765,-3.69911460150706,"Up"]
[874,"WP_THIAMINE_METABOLIC_PATHWAYS",2.84026193381162,0.0238707128121053,0.00559884947246893,0.00451459184858324,-0.172931851470516,-3.6472629058545,"Up"]
[875,"BIOCARTA_RACC_PATHWAY",2.84495679824635,0.0129617412486771,0.00551934965839363,0.0044486256187255,0.396443423430925,-3.63395285070942,"Up"]
[876,"REACTOME_NR1H3_NR1H2_REGULATE_GENE_EXPRESSION_LINKED_TO_CHOLESTEROL_TRANSPORT_AND_EFFLUX",2.84605587128902,0.0135995014960045,0.00550265059479578,0.00443330958851967,-0.227313341713784,-3.63083378027584,"Up"]
[877,"REACTOME_SPRY_REGULATION_OF_FGF_SIGNALING",2.84630589177172,0.0234880196128333,0.00550063780299148,0.00442983213081669,-0.213221788053551,-3.63012407664293,"Up"]
[878,"REACTOME_TETRAHYDROBIOPTERIN_BH4_SYNTHESIS_RECYCLING_SALVAGE_AND_REGULATION",2.85527247862182,0.0248475423820313,0.00535003392524148,0.00430674120972543,-0.149609066613929,-3.60463052565361,"Up"]
[879,"BIOCARTA_HBX_PATHWAY",2.86784237176795,0.027696150337909,0.00514647460734326,0.00413940467743128,-0.295835623945457,-3.56875732878631,"Up"]
[880,"REACTOME_TRAF3_DEPENDENT_IRF_ACTIVATION_PATHWAY",2.87668736253584,0.0182758748448874,0.00500660556834659,0.00402521628521253,-0.316661109628728,-3.54342028957767,"Up"]
[881,"WP_ATM_SIGNALING_PATHWAY",2.88161229975291,0.0127453973758392,0.0049352871346122,0.00396288238204354,-0.180530702350446,-3.52927871900808,"Up"]
[882,"REACTOME_RRNA_PROCESSING",2.88719958528144,0.0293339886113358,0.00485261843877408,0.00389322761383426,-0.157614140610649,-3.51320601588741,"Up"]
[883,"REACTOME_G_PROTEIN_MEDIATED_EVENTS",2.89689495354636,0.0111134143553362,0.00470920892333906,0.00377499338793981,-0.104479723168052,-3.48524197633725,"Up"]
[884,"REACTOME_NUCLEAR_ENVELOPE_NE_REASSEMBLY",2.90115817086105,0.0136445374212945,0.00464760754284692,0.00372404450548631,-0.185714825685865,-3.47291607927576,"Up"]
[885,"REACTOME_IRAK2_MEDIATED_ACTIVATION_OF_TAK1_COMPLEX",2.90257091904713,0.0301132967428056,0.00462865860538165,0.00370729943629421,-0.158885847715158,-3.46882752074454,"Up"]
[886,"REACTOME_RECYCLING_PATHWAY_OF_L1",2.90652094211089,0.0185123115145349,0.00457258281261084,0.00366084312224208,-0.152566125674956,-3.45738542208311,"Up"]
[887,"WP_PPAR_SIGNALING_PATHWAY",2.90692375300395,0.010498767684213,0.00456862803262951,0.00365613552408812,-0.0578697428560531,-3.45621771975844,"Up"]
[888,"REACTOME_NOTCH4_INTRACELLULAR_DOMAIN_REGULATES_TRANSCRIPTION",2.91041169749902,0.0182135341107112,0.00451988375764665,0.00361560202070857,-0.22204947870936,-3.44609981258277,"Up"]
[889,"REACTOME_DNA_DAMAGE_BYPASS",2.91490451521062,0.0152149751190416,0.00445724730750711,0.00356399329243989,-0.198666400189412,-3.43304909023048,"Up"]
[890,"WP_UREA_CYCLE_AND_RELATED_DISEASES",2.91975806880361,0.0259933460613716,0.00439031665383706,0.00350899465348853,-0.0605470625637348,-3.41892791250359,"Up"]
[891,"BIOCARTA_GRANULOCYTES_PATHWAY",2.92413620066788,0.0116993705536989,0.0043327332620268,0.00346004710904772,0.365426170816309,-3.40616982321601,"Up"]
[892,"WP_SMC1SMC3_ROLE_IN_DNA_DAMAGE_CORNELIA_DE_LANGE_SYNDROME",2.92482542212369,0.0227211764360297,0.00432498271183519,0.00345239848050002,-0.217227201129682,-3.40415965908687,"Up"]
[893,"REACTOME_NUCLEOTIDE_BIOSYNTHESIS",2.93697629165714,0.0210498625060302,0.00416095165749958,0.0033200575809671,-0.225502774740178,-3.36864307484375,"Up"]
[894,"REACTOME_FLT3_SIGNALING_BY_CBL_MUTANTS",2.9392518645352,0.0422121821123555,0.00413403759694995,0.00329579313144154,-0.174609856890076,-3.36197530338339,"Up"]
[895,"REACTOME_SULFIDE_OXIDATION_TO_SULFATE",2.94029245353245,0.032146630683951,0.00412193170641667,0.00328475124512692,-0.250077814334045,-3.35892450237331,"Up"]
[896,"REACTOME_ROLE_OF_PHOSPHOLIPIDS_IN_PHAGOCYTOSIS",2.94061471315971,0.0150870168140665,0.00411939322264205,0.00328133852856204,-0.0991362691991761,-3.35797948220788,"Up"]
[897,"REACTOME_COMPETING_ENDOGENOUS_RNAS_CERNAS_REGULATE_PTEN_TRANSLATION",2.95128618197603,0.0242743118265574,0.00398316445438398,0.00317013662209575,-0.308423565346708,-3.32662718196027,"Up"]
[898,"REACTOME_MAPK_TARGETS_NUCLEAR_EVENTS_MEDIATED_BY_MAP_KINASES",2.9577312737112,0.0164587460223666,0.00390253799771931,0.00310465067429897,-0.243956426002975,-3.30763685341212,"Up"]
[899,"KEGG_PENTOSE_AND_GLUCURONATE_INTERCONVERSIONS",2.96256498673823,0.0160515634056848,0.00384345337297371,0.00305634939274597,0.0786295639256236,-3.29336726984107,"Up"]
[900,"WP_MITOCHONDRIAL_COMPLEX_IV_ASSEMBLY",2.97024236389634,0.0252686957100882,0.00375034045958368,0.00298103985248959,-0.155614038554505,-3.27065508633275,"Up"]
[901,"WP_SARSCOV2_REPLICATION_ORGANELLE_FORMATION",2.98305913149199,0.0256745407332274,0.00359996393056942,0.00285908066550621,-0.266924294521397,-3.23260811143504,"Up"]
[902,"REACTOME_ATF4_ACTIVATES_GENES_IN_RESPONSE_TO_ENDOPLASMIC_RETICULUM_STRESS",2.98757484124985,0.0174342104292681,0.00354874841555798,0.00281720817199997,-0.297255589782745,-3.21916411152993,"Up"]
[903,"WP_VITAMIN_D_IN_INFLAMMATORY_DISEASES",3.00049925939973,0.0183493656220012,0.00340455466174419,0.00270044129883961,-0.234826943792662,-3.1805737836599,"Up"]
[904,"WP_RETT_SYNDROME_CAUSING_GENES",3.00136839356112,0.0133231570690337,0.00339630257223348,0.00269275001509739,-0.174545185264017,-3.1779727129007,"Up"]
[905,"REACTOME_OXIDATIVE_STRESS_INDUCED_SENESCENCE",3.00803689288211,0.0138141566150579,0.00332412267602333,0.00263440086571485,-0.25449509002319,-3.15799076663437,"Up"]
[906,"WP_VITAMIN_D_METABOLISM",3.01351707751835,0.0251088030666959,0.00326610235265801,0.00258731724832693,-0.119998258105271,-3.14153641617906,"Up"]
[907,"REACTOME_BIOSYNTHESIS_OF_EPA_DERIVED_SPMS",3.02170700394846,0.0285472073692295,0.00318044105098296,0.00251838567700979,-0.102986892497292,-3.11689027101864,"Up"]
[908,"REACTOME_SIGNALING_BY_ALK",3.02445614520075,0.0169377046731914,0.00315304218255798,0.00249562650481816,-0.194919991597071,-3.1086022389426,"Up"]
[909,"REACTOME_PTK6_REGULATES_CELL_CYCLE",3.03405095211833,0.0309462667889985,0.00305584121038433,0.00241766114654226,-0.280591529243497,-3.07961711729906,"Up"]
[910,"REACTOME_FBXW7_MUTANTS_AND_NOTCH1_IN_CANCER",3.03442659986014,0.0361813184376534,0.00305334306050297,0.00241465456606578,-0.253199098160577,-3.07848045148836,"Up"]
[911,"WP_CYTOSINE_METHYLATION",3.04045957655146,0.0239058770146833,0.00299415215077912,0.0023668348479337,-0.34541837995629,-3.0602061236497,"Up"]
[912,"REACTOME_PERK_REGULATES_GENE_EXPRESSION",3.0436306910529,0.0176609756895755,0.00296406143237238,0.0023420485406937,-0.264514852911359,-3.05058605294243,"Up"]
[913,"REACTOME_ACYL_CHAIN_REMODELLING_OF_PC",3.05600364585545,0.0174296769580028,0.00284573700113749,0.00224759457478504,-0.0522741809225723,-3.01295500202366,"Up"]
[914,"BIOCARTA_PGC1A_PATHWAY",3.05982400040281,0.0233018046346232,0.00281091514943336,0.00221914353902634,-0.200859066958426,-3.00130498961085,"Up"]
[915,"WP_HIJACK_OF_UBIQUITINATION_BY_SARSCOV2",3.06256256831386,0.0291385698296042,0.00278653045854709,0.002198952342288,-0.266853989206423,-2.99294489720214,"Up"]
[916,"BIOCARTA_LIS1_PATHWAY",3.06930697493875,0.0216192676060318,0.0027255900222355,0.00214994246693205,-0.105740660241132,-2.97232423991815,"Up"]
[917,"REACTOME_SIGNALING_BY_RETINOIC_ACID",3.0719328687625,0.013286232302277,0.00270290063507986,0.00213113319304373,-0.137442437900603,-2.96428346104749,"Up"]
[918,"REACTOME_MITOCHONDRIAL_UNCOUPLING",3.08371296241152,0.0144260275080516,0.00259933073209205,0.00204859534081209,0.146732174795484,-2.92812700999205,"Up"]
[919,"REACTOME_LRR_FLII_INTERACTING_PROTEIN_1_LRRFIP1_ACTIVATES_TYPE_I_IFN_PRODUCTION",3.08588493611195,0.0347862980637615,0.00258153789841884,0.0020337014145776,-0.326812265794874,-2.92144551841115,"Up"]
[920,"WP_CYTOPLASMIC_RIBOSOMAL_PROTEINS",3.09411711722352,0.0540500644923763,0.00251209574202392,0.00197814826649252,-0.155851813802502,-2.89607878917216,"Up"]
[921,"WP_SIGNAL_TRANSDUCTION_THROUGH_IL1R",3.10163842590791,0.0161475812456371,0.00245024043575001,0.0019286136763174,-0.202488744078877,-2.87284355744778,"Up"]
[922,"REACTOME_RECYCLING_OF_BILE_ACIDS_AND_SALTS",3.10703418579673,0.0251131828516441,0.0024070200115986,0.00189378227633196,-0.100823361740026,-2.85613998490175,"Up"]
[923,"REACTOME_ACTIVATED_NTRK2_SIGNALS_THROUGH_RAS",3.10880357620398,0.0278170036210311,0.00239368965470033,0.00188248670212769,-0.287887837665802,-2.85065619770192,"Up"]
[924,"WP_CAMKK2_PATHWAY",3.12198279612737,0.0171281695341809,0.00229014158317081,0.00180027998946964,-0.172314543176901,-2.80971238546724,"Up"]
[925,"WP_INSULIN_SIGNALING_IN_ADIPOCYTES_DIABETIC_CONDITION",3.12451653436557,0.0273893856083727,0.00227149917862852,0.00178485883502896,-0.275469482288123,-2.80182101323168,"Up"]
[926,"WP_INSULIN_SIGNALING_IN_ADIPOCYTES_NORMAL_CONDITION",3.12451653436557,0.0273893856083727,0.00227149917862852,0.00178485883502896,-0.275469482288123,-2.80182101323168,"Up"]
[927,"REACTOME_VLDLR_INTERNALISATION_AND_DEGRADATION",3.13974198840264,0.0265022891022089,0.00216049573646737,0.00169472084591317,-0.191187551514303,-2.75426645330324,"Up"]
[928,"REACTOME_SERINE_BIOSYNTHESIS",3.14603676710496,0.0278293822233308,0.00211547620687673,0.00165869322023668,-0.196007692733084,-2.73453815792351,"Up"]
[929,"REACTOME_GABA_B_RECEPTOR_ACTIVATION",3.15082408208731,0.0156627851213849,0.00208203038375445,0.00163176672788852,0.012795900372721,-2.71950795143416,"Up"]
[930,"WP_ACE_INHIBITOR_PATHWAY",3.15537682149962,0.0186579683882694,0.00205160061932457,0.00160653341344546,0.225279089905866,-2.7051930465216,"Up"]
[931,"WP_ASPIRIN_AND_MIRNAS",3.16390118941239,0.0220004598074233,0.00199421483380859,0.0015602510794879,-0.216807043335266,-2.67833489309364,"Up"]
[932,"REACTOME_N_GLYCAN_ANTENNAE_ELONGATION_IN_THE_MEDIAL_TRANS_GOLGI",3.1656044823046,0.0151456043248846,0.00198343984741088,0.00155115167553928,0.0161679821230452,-2.67295957019225,"Up"]
[933,"REACTOME_IL_6_TYPE_CYTOKINE_RECEPTOR_LIGAND_INTERACTIONS",3.16564985907912,0.0193566940350153,0.00198343984741088,0.00155090993153892,0.0125689964241361,-2.67281632876796,"Up"]
[934,"WP_ATM_SIGNALING_IN_DEVELOPMENT_AND_DISEASE",3.18109854795272,0.0136616408698695,0.00188205678455776,0.00147059497740748,-0.245711662002365,-2.62393010112522,"Up"]
[935,"WP_FOLATEALCOHOL_AND_CANCER_PATHWAY_HYPOTHESES",3.19247385591175,0.0256853515944633,0.0018103148067896,0.00141392671313021,-0.0810605822535663,-2.58778188462731,"Up"]
[936,"REACTOME_SIGNALING_BY_FGFR1",3.19661942388916,0.0155731653568678,0.00178529171095048,0.00139378037082976,-0.156582381366161,-2.57457615454786,"Up"]
[937,"REACTOME_SENSING_OF_DNA_DOUBLE_STRAND_BREAKS",3.20032141990867,0.0244828193929345,0.0017640591795386,0.00137601377297343,-0.305014659269052,-2.562768963335,"Up"]
[938,"REACTOME_CYTOSOLIC_TRNA_AMINOACYLATION",3.20461129937869,0.0324291213486297,0.00173875243871885,0.00135568720846129,-0.296327793346022,-2.54906970269913,"Up"]
[939,"WP_NANOPARTICLE_TRIGGERED_AUTOPHAGIC_CELL_DEATH",3.21338398259976,0.0182747778854515,0.00168727264898648,0.00131497969607246,-0.262229856966512,-2.52099805416404,"Up"]
[940,"REACTOME_HEPARAN_SULFATE_HEPARIN_HS_GAG_METABOLISM",3.21448907920943,0.0134223594130127,0.00168152449927666,0.00130993254683867,-0.110163594338699,-2.5174564292549,"Up"]
[941,"REACTOME_ERK_MAPK_TARGETS",3.22220007147318,0.0197377343543285,0.00163766117588886,0.0012752098495113,-0.233496304177206,-2.4927103221643,"Up"]
[942,"WP_CANCER_IMMUNOTHERAPY_BY_PD1_BLOCKADE",3.22441547796047,0.0174368076555916,0.00162575740024378,0.00126539214654602,0.0127939317242353,-2.48558969545173,"Up"]
[943,"BIOCARTA_IL1R_PATHWAY",3.22604783924051,0.0169455666397436,0.00161722183249128,0.00125820295064942,-0.200113233966359,-2.48033993112321,"Up"]
[944,"KEGG_RIBOSOME",3.24243597390416,0.0566706099627667,0.00152776278681405,0.00118808813212091,-0.162759737499275,-2.42748777607704,"Up"]
[945,"BIOCARTA_CPSF_PATHWAY",3.24770500402919,0.0244258532098925,0.00150107847611688,0.00116632379571429,-0.174498249659089,-2.41043821637616,"Up"]
[946,"REACTOME_IRE1ALPHA_ACTIVATES_CHAPERONES",3.24846338134403,0.015314380602713,0.00149773642246828,0.00116322174241633,-0.205810649951636,-2.40798197912203,"Up"]
[947,"WP_SELENIUM_MICRONUTRIENT_NETWORK",3.24883480261928,0.0129524710684461,0.00149643390820874,0.00116170527084626,-0.116902275769776,-2.40677880866208,"Up"]
[948,"REACTOME_ASSEMBLY_OF_ACTIVE_LPL_AND_LIPC_LIPASE_COMPLEXES",3.25003191827568,0.0208548038959443,0.00149080180210087,0.00115683000837787,0.0518393299097567,-2.40289997498578,"Up"]
[949,"REACTOME_GLYCOGEN_SYNTHESIS",3.27006731377699,0.0297309501851339,0.00139041301496033,0.00107799227678098,-0.14986986750698,-2.33777054962805,"Up"]
[950,"SA_G1_AND_S_PHASES",3.27486447294693,0.0240958765483672,0.00136763146732209,0.00105986824576209,-0.227937830482188,-2.32211704134545,"Up"]
[951,"REACTOME_TANDEM_PORE_DOMAIN_POTASSIUM_CHANNELS",3.28643176339463,0.0273144998310675,0.0013138713928115,0.00101731944888744,0.0691892226381875,-2.28427784170961,"Up"]
[952,"REACTOME_EUKARYOTIC_TRANSLATION_ELONGATION",3.30028785523755,0.0574948179427107,0.00125128168009486,0.000968434606659115,-0.158760478715005,-2.2387761217443,"Up"]
[953,"REACTOME_SELENOAMINO_ACID_METABOLISM",3.30248670239968,0.0521101908681063,0.00124206214768035,0.000960880062291174,-0.14774563008231,-2.2315378040368,"Up"]
[954,"BIOCARTA_NTHI_PATHWAY",3.30364623181216,0.0195397339158215,0.00123748073831618,0.000956918303718176,-0.254239595534976,-2.22771884641414,"Up"]
[955,"REACTOME_INTERACTION_WITH_CUMULUS_CELLS_AND_THE_ZONA_PELLUCIDA",3.31413711642615,0.0281885812577865,0.00119304978336332,0.000921755736809043,0.0978818877116485,-2.19310585469592,"Up"]
[956,"BIOCARTA_TPO_PATHWAY",3.31842690570701,0.021768645098813,0.00117540344082211,0.000907725531728006,-0.236633352255092,-2.17892082431436,"Up"]
[957,"REACTOME_SHC_MEDIATED_CASCADE_FGFR1",3.3372718602612,0.0203418379473757,0.00109906952582801,0.0008484045462532,-0.0469841741051949,-2.11638929352845,"Up"]
[958,"REACTOME_TERMINATION_OF_O_GLYCAN_BIOSYNTHESIS",3.33884055318119,0.0162498025831944,0.00109336514810963,0.000843632285332906,0.179400803469067,-2.11116810191035,"Up"]
[959,"REACTOME_TICAM1_TRAF6_DEPENDENT_INDUCTION_OF_TAK1_COMPLEX",3.34069468401364,0.0328269593963095,0.00108657151673623,0.000838023781126522,-0.172914079496377,-2.10499370851333,"Up"]
[960,"WP_MAPK_PATHWAY_IN_CONGENITAL_THYROID_CANCER",3.34193049090315,0.0242341622783484,0.00108222301860817,0.000834304857462775,-0.215236088801739,-2.10087647927759,"Up"]
[961,"REACTOME_RECOGNITION_AND_ASSOCIATION_OF_DNA_GLYCOSYLASE_WITH_SITE_CONTAINING_AN_AFFECTED_PURINE",3.34975057383524,0.0264572396920879,0.00105261522934931,0.00081112455594933,-0.174720923735068,-2.0747877502932,"Up"]
[962,"REACTOME_TRANSCRIPTIONAL_REGULATION_BY_SMALL_RNAS",3.35377136234449,0.0158116692300465,0.00103790651933626,0.000799440142930058,-0.280607255833321,-2.06135022548218,"Up"]
[963,"REACTOME_GDP_FUCOSE_BIOSYNTHESIS",3.35755820716441,0.0280351730078729,0.00102470275354605,0.000788578603521773,-0.125739218084827,-2.04867982855119,"Up"]
[964,"REACTOME_AMINO_ACIDS_REGULATE_MTORC1",3.36112757363414,0.0171100236575548,0.00101200632284691,0.000778466402189934,-0.152201326275612,-2.03672402427354,"Up"]
[965,"REACTOME_INTRINSIC_PATHWAY_OF_FIBRIN_CLOT_FORMATION",3.38180809119233,0.0214011610529228,0.000940107598472896,0.000722208165223612,0.0009248380936761,-1.96720382053501,"Up"]
[966,"REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS",3.38620863333075,0.00804715621592766,0.000925579678587685,0.000710735272761664,0.285981437962163,-1.95235590740723,"Up"]
[967,"REACTOME_NS1_MEDIATED_EFFECTS_ON_HOST_PATHWAYS",3.38647958390388,0.0154791293834723,0.000925073425886706,0.000710034427763919,-0.289518195232741,-1.95144106045776,"Up"]
[968,"BIOCARTA_FXR_PATHWAY",3.38654097986758,0.0390612465278041,0.000925073425886706,0.000709875709277163,-0.0988864946810588,-1.95123375083435,"Up"]
[969,"REACTOME_RORA_ACTIVATES_GENE_EXPRESSION",3.3934569326711,0.0229728312256441,0.000903036885139012,0.000692206411280646,-0.294372213633382,-1.9278573284571,"Up"]
[970,"WP_ARACHIDONATE_EPOXYGENASE_EPOXIDE_HYDROLASE",3.40072939373961,0.0452314743673505,0.000879760956727902,0.000674067858545568,-0.13022688351171,-1.90322453156699,"Up"]
[971,"REACTOME_GAP_FILLING_DNA_REPAIR_SYNTHESIS_AND_LIGATION_IN_GG_NER",3.41426304693235,0.0233215513403645,0.000837602930880711,0.000641484026011881,-0.183342720922801,-1.85724411082156,"Up"]
[972,"REACTOME_SEMA3A_PLEXIN_REPULSION_SIGNALING_BY_INHIBITING_INTEGRIN_ADHESION",3.414594456768,0.0241025814829789,0.000836954193899759,0.000640704813076435,-0.181842113703868,-1.85611586327836,"Up"]
[973,"REACTOME_AKT_PHOSPHORYLATES_TARGETS_IN_THE_NUCLEUS",3.41530769465288,0.0284022153143913,0.000835135528094714,0.000639030829189882,-0.278353623107789,-1.85368735426737,"Up"]
[974,"REACTOME_MRNA_EDITING_C_TO_U_CONVERSION",3.41612873621699,0.0232995750640099,0.000832991035887854,0.000637108865842701,0.170484519319628,-1.85089115681953,"Up"]
[975,"REACTOME_TRANSPORT_OF_ORGANIC_ANIONS",3.42306154462351,0.0310280570038445,0.000812409466811746,0.000621093067407361,0.131023110923411,-1.82725354118741,"Up"]
[976,"REACTOME_NONSENSE_MEDIATED_DECAY_NMD",3.43661006335171,0.0501765413180923,0.000773559466025884,0.000590869983496154,-0.155480525798993,-1.78092137608648,"Up"]
[977,"REACTOME_SIGNALING_BY_CTNNB1_PHOSPHO_SITE_MUTANTS",3.45135867645087,0.0272418566317994,0.000733176752005442,0.000559529626530469,-0.249731915448165,-1.73027754181802,"Up"]
[978,"REACTOME_REGULATION_OF_GENE_EXPRESSION_BY_HYPOXIA_INDUCIBLE_FACTOR",3.45643432059591,0.0278069122199747,0.000719837919799992,0.000549107131129481,-0.264237491540011,-1.71279870839457,"Up"]
[979,"WP_ANGIOGENESIS",3.46023868504723,0.0177819920624153,0.000710381218552871,0.000541414025880883,-0.213153605338775,-1.69968092956341,"Up"]
[980,"REACTOME_GALACTOSE_CATABOLISM",3.46400375432837,0.0355551773947833,0.000700831576962766,0.000533899359238166,-0.287427589707911,-1.6866844623938,"Up"]
[981,"REACTOME_TRNA_PROCESSING",3.46843426425952,0.0116925393946496,0.000689998521656837,0.000525181061018159,-0.262917777281028,-1.67137292339915,"Up"]
[982,"REACTOME_BETA_CATENIN_PHOSPHORYLATION_CASCADE",3.4703350312603,0.0258037392802463,0.000685441871694799,0.00052148158592165,-0.233661087671829,-1.66479801451569,"Up"]
[983,"PID_RB_1PATHWAY",3.4745278688074,0.0133545351687412,0.000675127611366493,0.000513406759790848,-0.192328200025097,-1.65028193234113,"Up"]
[984,"REACTOME_SIGNALING_BY_ACTIVIN",3.47487248616723,0.0219213058722058,0.000674560992684619,0.000512748284925252,-0.208641650369746,-1.64908804962134,"Up"]
[985,"REACTOME_PI5P_REGULATES_TP53_ACETYLATION",3.48132777300752,0.0274081078079473,0.000658816744173568,0.00050055847094429,-0.271105645310016,-1.6267026928783,"Up"]
[986,"BIOCARTA_BARR_MAPK_PATHWAY",3.48163429972477,0.0303013304566179,0.000658356171515248,0.000499986417706081,-0.12970112765352,-1.6256387018074,"Up"]
[987,"REACTOME_PROLONGED_ERK_ACTIVATION_EVENTS",3.48729458056215,0.0267930327656933,0.000645163443330242,0.000489531910947947,-0.273219349723396,-1.60597438142812,"Up"]
[988,"KEGG_FATTY_ACID_METABOLISM",3.49037774522416,0.0163966610967175,0.000638055654125361,0.00048392345157686,-0.150999553732626,-1.59524977880644,"Up"]
[989,"WP_PROSTAGLANDIN_SYNTHESIS_AND_REGULATION",3.50094826463257,0.0179485678426822,0.000613571447300146,0.000465146775331791,-0.0513988602180182,-1.5584090495302,"Up"]
[990,"REACTOME_KSRP_KHSRP_BINDS_AND_DESTABILIZES_MRNA",3.52330086830616,0.0225218094754669,0.000564371406201333,0.00042765795490155,-0.322462283462507,-1.4801388335135,"Up"]
[991,"REACTOME_IONOTROPIC_ACTIVITY_OF_KAINATE_RECEPTORS",3.53398085925677,0.0254760546777753,0.00054231287094766,0.000410759917435053,0.0811918509957281,-1.44256608249066,"Up"]
[992,"REACTOME_ACTIVATION_OF_RAC1_DOWNSTREAM_OF_NMDARS",3.53666857036862,0.0343821197293822,0.000537068772169751,0.000406606722249973,-0.162032480263483,-1.43309270197058,"Up"]
[993,"REACTOME_SYNTHESIS_OF_PIPS_AT_THE_EARLY_ENDOSOME_MEMBRANE",3.53852123481794,0.0205414377395349,0.000533555365967588,0.000403766763112449,-0.265329902894881,-1.42655842677776,"Up"]
[994,"REACTOME_MITOTIC_SPINDLE_CHECKPOINT",3.54084832879845,0.0124400925065191,0.000529112081840456,0.000400225805494704,-0.157489334339538,-1.41834601769766,"Up"]
[995,"REACTOME_RESPONSE_OF_EIF2AK4_GCN2_TO_AMINO_ACID_DEFICIENCY",3.54546010096636,0.0564825737441215,0.000520180011169491,0.0003932939962992,-0.155182082406896,-1.40205496504187,"Up"]
[996,"WP_GLYCEROLIPIDS_AND_GLYCEROPHOSPHOLIPIDS",3.54720261084098,0.0172697388545085,0.000516985396171159,0.000390704213030836,-0.243340607927226,-1.39589405225232,"Up"]
[997,"REACTOME_TELOMERE_C_STRAND_SYNTHESIS_INITIATION",3.5567022119443,0.0254330017385451,0.000498894018500109,0.00037686359899519,-0.206805254381646,-1.3622536108743,"Up"]
[998,"REACTOME_SNRNP_ASSEMBLY",3.56529940614786,0.0163355094615313,0.000483268711847521,0.000364734179623112,-0.251696551452971,-1.33173140952293,"Up"]
[999,"BIOCARTA_SARS_PATHWAY",3.57495296288225,0.0361769904886757,0.000466007993875967,0.000351549890116958,-0.192808676760775,-1.29737119986892,"Up"]
[1000,"BIOCARTA_EEA1_PATHWAY",3.58001798924094,0.0351882603690624,0.000457280862789196,0.00034481198661736,-0.273850193588451,-1.27930600166562,"Up"]
[1001,"KEGG_CARDIAC_MUSCLE_CONTRACTION",3.59015386321013,0.0267013502513844,0.000440272372183357,0.000331689678503858,-0.0719832941264017,-1.24307818953095,"Up"]
[1002,"KEGG_AMYOTROPHIC_LATERAL_SCLEROSIS_ALS",3.60135168431639,0.0143533171133038,0.000422129673388001,0.000317736606386178,-0.159103756809596,-1.20293589944107,"Up"]
[1003,"WP_GPR40_PATHWAY",3.60302898487357,0.0234024943619712,0.00041960477263308,0.000315694548910853,-0.0964003370300557,-1.19691231770021,"Up"]
[1004,"REACTOME_TOLL_LIKE_RECEPTOR_CASCADES",3.60447605636544,0.0130387739570592,0.000417650837742428,0.000313942667506791,-0.181589555287665,-1.19171329355829,"Up"]
[1005,"WP_MITOCHONDRIAL_IMMUNE_RESPONSE_TO_SARSCOV2",3.61220991448621,0.0168294451363754,0.000405945528144578,0.000304733063468855,-0.185117202793119,-1.16389184095685,"Up"]
[1006,"REACTOME_ADP_SIGNALLING_THROUGH_P2Y_PURINOCEPTOR_1",3.62156199591493,0.021516585996885,0.000391736378521828,0.000293934448661452,-0.0911331196444427,-1.13016956821265,"Up"]
[1007,"WP_SRF_AND_MIRS_IN_SMOOTH_MUSCLE_DIFFERENTIATION_AND_PROLIFERATION",3.64232027683738,0.0324142496032961,0.000361806930939661,0.000271233131089044,-0.226664875144481,-1.05500722575577,"Up"]
[1008,"WP_PHASE_I_BIOTRANSFORMATIONS_NON_P450",3.64371769028137,0.0324377864399664,0.000360011277617485,0.000269765535623628,-0.156534111946907,-1.04993201825624,"Up"]
[1009,"BIOCARTA_DEATH_PATHWAY",3.64729202041905,0.0210150571455058,0.00035520668606261,0.000266045493609647,-0.217139123786483,-1.03694171783914,"Up"]
[1010,"REACTOME_MUCOPOLYSACCHARIDOSES",3.64808326715041,0.0264644922978468,0.000354275497565569,0.000265228518589068,-0.181591549992524,-1.03406434662896,"Up"]
[1011,"REACTOME_IRS_ACTIVATION",3.65064447916519,0.0366773095077825,0.000350922802078753,0.00026260012652182,-0.217332577407964,-1.02474621982216,"Up"]
[1012,"REACTOME_NGF_STIMULATED_TRANSCRIPTION",3.6513989783715,0.0220865685798839,0.000350052152003662,0.000261830506407597,-0.187592472185674,-1.02199997835104,"Up"]
[1013,"REACTOME_NOD1_2_SIGNALING_PATHWAY",3.65816093114996,0.0207202187900605,0.000341109901676395,0.000255026836071151,-0.200998477197803,-0.997362402564576,"Up"]
[1014,"WP_FTO_OBESITY_VARIANT_MECHANISM",3.67077887449447,0.0359052697071301,0.000325012158310574,0.00024277223970972,-0.0838952375963842,-0.951266535883316,"Up"]
[1015,"REACTOME_SIGNALING_BY_FLT3_ITD_AND_TKD_MUTANTS",3.68186546775166,0.025616426294726,0.000311492044252033,0.000232463023578103,-0.207457879209398,-0.910634269596714,"Up"]
[1016,"BIOCARTA_TUBBY_PATHWAY",3.68366261197141,0.0339040966553309,0.000309445223141131,0.00023083110268726,0.138857176721642,-0.904036234497208,"Up"]
[1017,"REACTOME_ACYL_CHAIN_REMODELING_OF_DAG_AND_TAG",3.70065312806296,0.0336000990578615,0.000289856095357209,0.000215925188444237,-0.190664024005492,-0.84149847311806,"Up"]
[1018,"REACTOME_TOLL_LIKE_RECEPTOR_TLR1_TLR2_CASCADE",3.70683623857762,0.0153904155214208,0.00028300852357796,0.000210728681355114,-0.20209382088794,-0.818668746628906,"Up"]
[1019,"WP_NANOPARTICLE_TRIGGERED_REGULATED_NECROSIS",3.70718525835289,0.0272429129053143,0.000282747439214535,0.000210438883571951,-0.199585612172553,-0.817378936639228,"Up"]
[1020,"WP_SEROTONIN_HTR1_GROUP_AND_FOS_PATHWAY",3.70962156296101,0.0207818987217065,0.000280170420516979,0.000208426375587024,-0.222310520003585,-0.808372145908677,"Up"]
[1021,"WP_SUPRESSION_OF_HMGB1_MEDIATED_INFLAMMATION_BY_THBD",3.71026756767114,0.0329696156564261,0.000279583985565216,0.000207895784138238,-0.2383650375037,-0.805982936372647,"Up"]
[1022,"REACTOME_RETROGRADE_TRANSPORT_AT_THE_TRANS_GOLGI_NETWORK",3.71235319890471,0.016668172594756,0.000277417770697007,0.000206191413240724,-0.24512112359318,-0.798266521005073,"Up"]
[1023,"WP_ESTROGEN_RECEPTOR_PATHWAY",3.714558825263,0.0299896259691455,0.00027513682450464,0.000204403268407293,-0.16239705224281,-0.790101440006088,"Up"]
[1024,"WP_KYNURENINE_PATHWAY_AND_LINKS_TO_CELL_SENESCENCE",3.71490934027375,0.0201749849339388,0.000274880961514124,0.000204120444093315,-0.0843247029224197,-0.78880341126925,"Up"]
[1025,"REACTOME_JNK_C_JUN_KINASES_PHOSPHORYLATION_AND_ACTIVATION_MEDIATED_BY_ACTIVATED_HUMAN_TAK1",3.72673997837218,0.0253981319187751,0.000262431661636112,0.000194787333198194,-0.210876772932565,-0.744920460053841,"Up"]
[1026,"REACTOME_THROMBOXANE_SIGNALLING_THROUGH_TP_RECEPTOR",3.72914342519429,0.0225823151229615,0.000260062293302109,0.00019294095241948,-0.0645745398452971,-0.735988426911052,"Up"]
[1027,"WP_MIR222_IN_EXERCISEINDUCED_CARDIAC_GROWTH",3.72961951076797,0.0384630509819254,0.000259690051353081,0.000192577170335382,-0.34542396345793,-0.73421844767938,"Up"]
[1028,"REACTOME_DISEASES_OF_IMMUNE_SYSTEM",3.73623067735915,0.0204578870144398,0.000253082264064254,0.000187591678187978,-0.148775938450759,-0.709616310297558,"Up"]
[1029,"PID_BCR_5PATHWAY",3.73639838632073,0.0155871886242857,0.000253028960563255,0.000187466800741197,-0.189291775969258,-0.708991649398085,"Up"]
[1030,"WP_PREGNANE_X_RECEPTOR_PATHWAY",3.73992162952509,0.0227145755162832,0.000249626002874099,0.000184861361777546,-0.1262644095156,-0.695862255540795,"Up"]
[1031,"REACTOME_TOLL_LIKE_RECEPTOR_9_TLR9_CASCADE",3.74673579426179,0.0153807337268394,0.000243062311711088,0.000179918593756453,-0.215115726868792,-0.670434180859495,"Up"]
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[1033,"PID_MAPK_TRK_PATHWAY",3.75020410682691,0.0201783644619625,0.0002399471329867,0.000177450781210137,-0.245124876477382,-0.657473916196436,"Up"]
[1034,"REACTOME_EXTENSION_OF_TELOMERES",3.76116125939941,0.014924071633579,0.000229790404183696,0.00016986193507641,-0.15864024495217,-0.616451011071953,"Up"]
[1035,"REACTOME_TRAF6_MEDIATED_IRF7_ACTIVATION",3.76754407643605,0.0233121043527297,0.000224104215256355,0.000165583074025444,-0.305024194304752,-0.592499090079764,"Up"]
[1036,"PID_P38_ALPHA_BETA_DOWNSTREAM_PATHWAY",3.77550982878069,0.0199979538761957,0.000217168543036343,0.000160385270143912,-0.219850785486917,-0.56255025917083,"Up"]
[1037,"REACTOME_DNA_DAMAGE_REVERSAL",3.77609331271364,0.0291456426690562,0.000216760293628467,0.000160010635107654,-0.291016842222137,-0.560354054285243,"Up"]
[1038,"BIOCARTA_PLK3_PATHWAY",3.77724212772435,0.0313836315645483,0.00021586299184903,0.000159275426172007,-0.125652340645358,-0.556028981207138,"Up"]
[1039,"REACTOME_NUCLEAR_EVENTS_KINASE_AND_TRANSCRIPTION_FACTOR_ACTIVATION",3.80677117078528,0.0190301569796471,0.000191857926242054,0.000141433727678437,-0.202857406108094,-0.44440714077337,"Up"]
[1040,"REACTOME_RRNA_MODIFICATION_IN_THE_NUCLEUS_AND_CYTOSOL",3.80838373183546,0.0222051021030925,0.000190699970078807,0.000140515767426489,-0.237511382653826,-0.438286572999881,"Up"]
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[1042,"BIOCARTA_EIF4_PATHWAY",3.8151441204842,0.0252452037905162,0.000185729662994578,0.000136728112231501,-0.219377030616142,-0.412598980623754,"Up"]
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[1044,"REACTOME_MET_RECEPTOR_ACTIVATION",3.82017022304522,0.0522269328959559,0.000182240018123808,0.000133974696184811,-0.139226868097719,-0.393471731109196,"Up"]
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[1046,"REACTOME_SUMOYLATION_OF_SUMOYLATION_PROTEINS",3.82385053195241,0.0186244216096168,0.00017970766681137,0.000131991764726165,-0.292905489942253,-0.379450075918735,"Up"]
[1047,"KEGG_SPHINGOLIPID_METABOLISM",3.83246515000665,0.0186784653785707,0.000173614469086215,0.00012745785584737,-0.131107728220459,-0.346576461893929,"Up"]
[1048,"WP_TUMOR_SUPPRESSOR_ACTIVITY_OF_SMARCB1",3.84404930315127,0.0201063917584155,0.000165853251494867,0.000121592144230211,-0.259651052995804,-0.302254662090966,"Up"]
[1049,"WP_SYNAPTIC_VESICLE_PATHWAY",3.84876487781965,0.0173254666332918,0.000162846702201171,0.000119278066963138,-0.0685971267691662,-0.284174312720092,"Up"]
[1050,"BIOCARTA_PITX2_PATHWAY",3.85857321879342,0.0242934533993286,0.000156528135885184,0.000114597184504335,-0.288611386513922,-0.246496553966033,"Up"]
[1051,"REACTOME_CELLULAR_RESPONSE_TO_HEAT_STRESS",3.86146118341522,0.0172035627677957,0.000154762499692605,0.000113252315058455,-0.198593044641239,-0.235384493984443,"Up"]
[1052,"REACTOME_NF_KB_ACTIVATION_THROUGH_FADD_RIP_1_PATHWAY_MEDIATED_BY_CASPASE_8_AND_10",3.86152230243214,0.0230868737012786,0.000154762499692605,0.000113224014645415,-0.306073476156763,-0.235149235898093,"Up"]
[1053,"WP_REGULATION_OF_WNT_BCATENIN_SIGNALING_BY_SMALL_MOLECULE_COMPOUNDS",3.86240482087561,0.0263000613474205,0.00015430870987422,0.000112816118184019,-0.164944034713708,-0.23175184958798,"Up"]
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[1055,"WP_22Q112_COPY_NUMBER_VARIATION_SYNDROME",3.88170186521525,0.0131840615479878,0.000142770820158861,0.000104236185837981,-0.108795288945076,-0.157271362826241,"Up"]
[1056,"WP_MAPK_AND_NFKB_SIGNALING_PATHWAYS_INHIBITED_BY_YERSINIA_YOPJ",3.89679990264213,0.0299490577310463,0.000134356143224801,{"v":9.79566887681495e-05,"d":"9.80E-05"},-0.237843272068579,-0.0987394910498276,"Up"]
[1057,"BIOCARTA_MHC_PATHWAY",3.89695967211443,0.0388111045593409,0.000134329837675458,{"v":9.78921893991193e-05,"d":"9.79E-05"},-0.135124525330231,-0.0981188867250804,"Up"]
[1058,"REACTOME_SYNTHESIS_OF_IP3_AND_IP4_IN_THE_CYTOSOL",3.90221830690417,0.0190005983448879,0.000131508120003916,{"v":9.57915084643908e-05,"d":"9.58E-05"},-0.0150295122212221,-0.0776782164078789,"Up"]
[1059,"REACTOME_SRP_DEPENDENT_COTRANSLATIONAL_PROTEIN_TARGETING_TO_MEMBRANE",3.90725371274637,0.0585532351513839,0.000128861147410487,{"v":9.3819958202372e-05,"d":"9.38E-05"},-0.166825578265772,-0.0580794781394687,"Up"]
[1060,"REACTOME_HDL_REMODELING",3.90883419545296,0.0363293492453197,0.000128081468177656,{"v":9.3209084635359e-05,"d":"9.32E-05"},-0.0735220280365398,-0.0519227455998097,"Up"]
[1061,"KEGG_CALCIUM_SIGNALING_PATHWAY",3.91610256984584,0.00823700812813461,0.000124344790195076,{"v":9.04478298450012e-05,"d":"9.04E-05"},0.0363585571640095,-0.0235769871079405,"Up"]
[1062,"BIOCARTA_CELL2CELL_PATHWAY",3.9184760337329,0.0305202986377336,0.000123185512240228,{"v":8.95630158156855e-05,"d":"8.96E-05"},-0.0295559942946068,-0.0143093936225149,"Up"]
[1063,"REACTOME_NRAGE_SIGNALS_DEATH_THROUGH_JNK",3.91875552474739,0.0150427761644819,0.000123100070506935,{"v":8.94593629797364e-05,"d":"8.95E-05"},-0.166559542670913,-0.0132177047354176,"Up"]
[1064,"PID_FRA_PATHWAY",3.9222787903356,0.0215967822183955,0.000121371733563884,{"v":8.81623962088533e-05,"d":"8.82E-05"},-0.150151335187886,0.000550794445002722,"Up"]
[1065,"BIOCARTA_GCR_PATHWAY",3.93292473825032,0.03178237645837,0.000116178007234681,{"v":8.43505639571637e-05,"d":"8.44E-05"},-0.204248852876345,0.0422288838025153,"Up"]
[1066,"REACTOME_ARYL_HYDROCARBON_RECEPTOR_SIGNALLING",3.94102029374947,0.038284889638679,0.000112382237091234,{"v":8.15567449336181e-05,"d":"8.16E-05"},-0.186468203511481,0.0739978156188013,"Up"]
[1067,"REACTOME_GLYCOGEN_METABOLISM",3.94118428240418,0.0266920022199001,0.0001123577485988,{"v":8.15010659539201e-05,"d":"8.15E-05"},-0.186211878207186,0.0746420204926608,"Up"]
[1068,"REACTOME_NF_KB_IS_ACTIVATED_AND_SIGNALS_SURVIVAL",3.94288631672715,0.0374179511534359,0.00011161589986354,{"v":8.09252931196851e-05,"d":"8.09E-05"},-0.16480863319765,0.0813297865970855,"Up"]
[1069,"REACTOME_ATTACHMENT_AND_ENTRY",3.94640761737012,0.0405884914372751,0.000110040948279071,{"v":7.97462742589216e-05,"d":"7.97E-05"},0.00815375021031352,0.0951751008520754,"Up"]
[1070,"REACTOME_GLYCOGEN_BREAKDOWN_GLYCOGENOLYSIS",3.94887290192734,0.0268979959653,0.000108966028864326,{"v":7.89305209081335e-05,"d":"7.89E-05"},-0.240147203280571,0.104875629705147,"Up"]
[1071,"REACTOME_CLEC7A_DECTIN_1_INDUCES_NFAT_ACTIVATION",3.9493876010995,0.034058657526168,0.000108782953743475,{"v":7.87612073999657e-05,"d":"7.88E-05"},-0.275862626370661,0.106901657153545,"Up"]
[1072,"KEGG_PROTEIN_EXPORT",3.97581796102839,0.031033570816538,{"v":9.74375395783485e-05,"d":"9.74E-05"},{"v":7.05140089053838e-05,"d":"7.05E-05"},-0.24674520349241,0.211294440001187,"Up"]
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[1074,"REACTOME_INTERACTIONS_OF_REV_WITH_HOST_CELLULAR_PROTEINS",3.97976419853378,0.0204763739160674,{"v":9.59255892883653e-05,"d":"9.59E-05"},{"v":6.9355107235144e-05,"d":"6.94E-05"},-0.283435394592875,0.226940610351392,"Up"]
[1075,"REACTOME_G_PROTEIN_ACTIVATION",3.98426353918191,0.0258522180322821,{"v":9.41724059112678e-05,"d":"9.42E-05"},{"v":6.80557670249445e-05,"d":"6.81E-05"},-0.0649850556179724,0.244798634014366,"Up"]
[1076,"BIOCARTA_RNAPOL3_PATHWAY",3.99044632070054,0.0351415258095391,{"v":9.17965218208256e-05,"d":"9.18E-05"},{"v":6.63078114771888e-05,"d":"6.63E-05"},-0.259061075593028,0.269371122208534,"Up"]
[1077,"KEGG_BASE_EXCISION_REPAIR",3.99730720560707,0.0206077688596728,{"v":8.9221817209062e-05,"d":"8.92E-05"},{"v":6.44179112103214e-05,"d":"6.44E-05"},-0.200313115141048,0.296683116162018,"Up"]
[1078,"REACTOME_ENOS_ACTIVATION",4.00561167180852,0.0361344538782163,{"v":8.61881821785215e-05,"d":"8.62E-05"},{"v":6.21985565721516e-05,"d":"6.22E-05"},-0.203104304695553,0.329804368130857,"Up"]
[1079,"REACTOME_ZINC_TRANSPORTERS",4.00641493006523,0.0238249175505459,{"v":8.59362726642016e-05,"d":"8.59E-05"},{"v":6.19877702280914e-05,"d":"6.20E-05"},-0.192641498761996,0.333011693213324,"Up"]
[1080,"WP_CANONICAL_NFKB_PATHWAY",4.00770447655271,0.0366427187757011,{"v":8.55090960205692e-05,"d":"8.55E-05"},{"v":6.16507888650325e-05,"d":"6.17E-05"},-0.243256915081471,0.338162057330001,"Up"]
[1081,"REACTOME_RHO_GTPASES_ACTIVATE_IQGAPS",4.01440743738665,0.0369979748564068,{"v":8.31570557215274e-05,"d":"8.32E-05"},{"v":5.99269470381857e-05,"d":"5.99E-05"},-0.1607342872496,0.364959876814567,"Up"]
[1082,"REACTOME_METAL_ION_SLC_TRANSPORTERS",4.03613181607998,0.0194784901555859,{"v":7.58677507915029e-05,"d":"7.59E-05"},{"v":5.46483292644597e-05,"d":"5.46E-05"},-0.13337657975452,0.452118950405783,"Up"]
[1083,"REACTOME_REGULATION_OF_GENE_EXPRESSION_IN_BETA_CELLS",4.03720614386897,0.0233898626824262,{"v":7.5557099245612e-05,"d":"7.56E-05"},{"v":5.43990721289258e-05,"d":"5.44E-05"},0.0976456355738805,0.456441372441516,"Up"]
[1084,"REACTOME_TRNA_PROCESSING_IN_THE_NUCLEUS",4.04230707285608,0.0166779702842946,{"v":7.39682993713738e-05,"d":"7.40E-05"},{"v":5.32302235354724e-05,"d":"5.32E-05"},-0.281448421531696,0.476979974128813,"Up"]
[1085,"WP_NODLIKE_RECEPTOR_NLR_SIGNALING_PATHWAY",4.04660521544934,0.030444968885375,{"v":7.26594911446072e-05,"d":"7.27E-05"},{"v":5.22638445075245e-05,"d":"5.23E-05"},-0.249402455624533,0.494306284328196,"Up"]
[1086,"KEGG_GLYCEROPHOSPHOLIPID_METABOLISM",4.04817721272053,0.0127192193231683,{"v":7.22077875421608e-05,"d":"7.22E-05"},{"v":5.19145732970123e-05,"d":"5.19E-05"},-0.145033555177054,0.500647774457198,"Up"]
[1087,"WP_OXIDATIVE_DAMAGE_RESPONSE",4.05119224140393,0.0200529128807297,{"v":7.13181068324025e-05,"d":"7.13E-05"},{"v":5.12508662459573e-05,"d":"5.13E-05"},-0.149337654247998,0.51281737701458,"Up"]
[1088,"WP_LET7_INHIBITION_OF_ES_CELL_REPROGRAMMING",4.05174754129636,0.0517983270191466,{"v":7.11826483145803e-05,"d":"7.12E-05"},{"v":5.11295068359451e-05,"d":"5.11E-05"},-0.154920243195057,0.515059727312634,"Up"]
[1089,"REACTOME_BINDING_OF_TCF_LEF_CTNNB1_TO_TARGET_GENE_PROMOTERS",4.05694756867121,0.0356237426794444,{"v":6.96842343046127e-05,"d":"6.97E-05"},{"v":5.00061964797271e-05,"d":"5.00E-05"},-0.130832922972157,0.536072776892151,"Up"]
[1090,"KEGG_MTOR_SIGNALING_PATHWAY",4.07125387912484,0.0187695066646741,{"v":6.56058431580028e-05,"d":"6.56E-05"},{"v":4.70352283099716e-05,"d":"4.70E-05"},-0.230773660681898,0.594022579585863,"Up"]
[1091,"WP_CIRCADIAN_RHYTHM_GENES",4.07979127473855,0.0124613504208586,{"v":6.33048694824813e-05,"d":"6.33E-05"},{"v":4.53428602939635e-05,"d":"4.53E-05"},-0.144885270883439,0.628701493101598,"Up"]
[1092,"PID_PTP1B_PATHWAY",4.08260998073352,0.0169698001344107,{"v":6.25721164186539e-05,"d":"6.26E-05"},{"v":4.47969065588339e-05,"d":"4.48E-05"},-0.0757069515905103,0.640166992129929,"Up"]
[1093,"BIOCARTA_CCR3_PATHWAY",4.09247086299775,0.0301520635352492,{"v":6.00571760327932e-05,"d":"6.01E-05"},{"v":4.29356126901109e-05,"d":"4.29E-05"},-0.182072643413456,0.680339722913081,"Up"]
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[1097,"REACTOME_MITOCHONDRIAL_IRON_SULFUR_CLUSTER_BIOGENESIS",4.11934638553516,0.0282922226580775,{"v":5.3649622887759e-05,"d":"5.36E-05"},{"v":3.82280713694153e-05,"d":"3.82E-05"},-0.268439131863224,0.790319978156893,"Up"]
[1098,"REACTOME_DOWNREGULATION_OF_ERBB2_ERBB3_SIGNALING",4.12559531444139,0.036460253237245,{"v":5.22399433811544e-05,"d":"5.22E-05"},{"v":3.72059785686967e-05,"d":"3.72E-05"},-0.236290082522237,0.81599478538854,"Up"]
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[1100,"KEGG_GLYCOSPHINGOLIPID_BIOSYNTHESIS_LACTO_AND_NEOLACTO_SERIES",4.13361394036938,0.0193002486298025,{"v":5.04995941677523e-05,"d":"5.05E-05"},{"v":3.59324035424391e-05,"d":"3.59E-05"},0.0372556732811046,0.848997562815601,"Up"]
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[1102,"REACTOME_CAMK_IV_MEDIATED_PHOSPHORYLATION_OF_CREB",4.14223534914452,0.0286212499148317,{"v":4.86862947290587e-05,"d":"4.87E-05"},{"v":3.46093194986932e-05,"d":"3.46E-05"},-0.132989514986879,0.88455255579278,"Up"]
[1103,"REACTOME_LINOLEIC_ACID_LA_METABOLISM",4.14574841323236,0.0352363026537139,{"v":4.7969468037211e-05,"d":"4.80E-05"},{"v":3.40835693948605e-05,"d":"3.41E-05"},-0.0432509105630483,0.899061743049083,"Up"]
[1104,"BIOCARTA_HDAC_PATHWAY",4.1521735846191,0.0266725957703469,{"v":4.66658540400236e-05,"d":"4.67E-05"},{"v":3.31415731289641e-05,"d":"3.31E-05"},-0.222947188455794,0.925629862801237,"Up"]
[1105,"REACTOME_GLYCEROPHOSPHOLIPID_CATABOLISM",4.15263991019826,0.035171778031881,{"v":4.65930889883991e-05,"d":"4.66E-05"},{"v":3.30741765288771e-05,"d":"3.31E-05"},-0.0696616385970707,0.927559718912036,"Up"]
[1106,"REACTOME_INTESTINAL_ABSORPTION",4.15633869541648,0.034178497116686,{"v":4.58682819568175e-05,"d":"4.59E-05"},{"v":3.25441960037744e-05,"d":"3.25E-05"},0.290916811884812,0.94287454213254,"Up"]
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[1876,"REACTOME_MET_ACTIVATES_RAP1_AND_RAC1",7.33559977419563,0.0595064312467241,{"v":5.6407402783016e-13,"d":"5.64E-13"},{"v":2.33698686294007e-13,"d":"2.34E-13"},-0.276083671279274,19.1239412278222,"Up"]
[1877,"REACTOME_FORMATION_OF_TC_NER_PRE_INCISION_COMPLEX",7.33922141798398,0.0410455995989357,{"v":5.49528478981912e-13,"d":"5.50E-13"},{"v":2.27486991805265e-13,"d":"2.27E-13"},-0.265345598972309,19.150351505941,"Up"]
[1878,"REACTOME_INFECTION_WITH_MYCOBACTERIUM_TUBERCULOSIS",7.33929189509559,0.0550050195409736,{"v":5.49528478981912e-13,"d":"5.50E-13"},{"v":2.27367735804327e-13,"d":"2.27E-13"},-0.172664092051034,19.1508655776416,"Up"]
[1879,"BIOCARTA_WNT_PATHWAY",7.34393568162055,0.0453982413225593,{"v":5.31448256545472e-13,"d":"5.31E-13"},{"v":2.19643763248382e-13,"d":"2.20E-13"},-0.239378280633916,19.1847489135607,"Up"]
[1880,"WP_NUCLEAR_RECEPTORS_METAPATHWAY",7.34737535384733,0.0218452748853566,{"v":5.18432064317913e-13,"d":"5.18E-13"},{"v":2.14089354495656e-13,"d":"2.14E-13"},-0.12274409052422,19.209860146425,"Up"]
[1881,"REACTOME_SWITCHING_OF_ORIGINS_TO_A_POST_REPLICATIVE_STATE",7.35407802369386,0.0440031940554672,{"v":4.93578502936966e-13,"d":"4.94E-13"},{"v":2.03659416022911e-13,"d":"2.04E-13"},-0.165491561724083,19.2588263075365,"Up"]
[1882,"REACTOME_ADHERENS_JUNCTIONS_INTERACTIONS",7.35573675732772,0.0516693968102745,{"v":4.87911122510223e-13,"d":"4.88E-13"},{"v":2.01156339982285e-13,"d":"2.01E-13"},-0.0559395303546419,19.2709509734725,"Up"]
[1883,"PID_CERAMIDE_PATHWAY",7.3560229354752,0.0373186262822168,{"v":4.87269843805432e-13,"d":"4.87E-13"},{"v":2.00727557114181e-13,"d":"2.01E-13"},-0.209488155961477,19.2730430932455,"Up"]
[1884,"BIOCARTA_NFAT_PATHWAY",7.35628053028206,0.0375721514639291,{"v":4.86733427459116e-13,"d":"4.87E-13"},{"v":2.00342368927166e-13,"d":"2.00E-13"},-0.178015923645129,19.2749263220966,"Up"]
[1885,"BIOCARTA_PTC1_PATHWAY",7.3569714072792,0.0524493411772685,{"v":4.8462947662892e-13,"d":"4.85E-13"},{"v":1.99312865050828e-13,"d":"1.99E-13"},-0.163493896145167,19.2799775212909,"Up"]
[1886,"REACTOME_ERYTHROPOIETIN_ACTIVATES_STAT5",7.35947630031182,0.0571887450474941,{"v":4.7604961057805e-13,"d":"4.76E-13"},{"v":1.95623625399482e-13,"d":"1.96E-13"},-0.114661771774277,19.2982954552842,"Up"]
[1887,"BIOCARTA_TCR_PATHWAY",7.37822520353986,0.0384617114490639,{"v":4.141828571753e-13,"d":"4.14E-13"},{"v":1.70060909980546e-13,"d":"1.70E-13"},-0.165680303233275,19.4355999520914,"Up"]
[1888,"BIOCARTA_CBL_PATHWAY",7.38369314582206,0.0569580699671523,{"v":3.97909723873328e-13,"d":"3.98E-13"},{"v":1.63245014922391e-13,"d":"1.63E-13"},-0.157161293249066,19.4757087787087,"Up"]
[1889,"WP_PHOTODYNAMIC_THERAPYINDUCED_NFE2L2_NRF2_SURVIVAL_SIGNALING",7.38414708271411,0.0446274033256686,{"v":3.9688666364677e-13,"d":"3.97E-13"},{"v":1.6269139552322e-13,"d":"1.63E-13"},-0.136102241220002,19.4790398525238,"Up"]
[1890,"WP_SULINDAC_METABOLIC_PATHWAY",7.39181397118883,0.0734794175532862,{"v":3.75053101733326e-13,"d":"3.75E-13"},{"v":1.5361486690427e-13,"d":"1.54E-13"},-0.154276674141124,19.5353315949878,"Up"]
[1891,"BIOCARTA_AKT_PATHWAY",7.39376947566923,0.0494346393734352,{"v":3.69902897255719e-13,"d":"3.70E-13"},{"v":1.51380639126581e-13,"d":"1.51E-13"},-0.229438791694714,19.5496985502825,"Up"]
[1892,"WP_METHYLATION_PATHWAYS",7.39579917221145,0.0673410728215616,{"v":3.64619494307439e-13,"d":"3.65E-13"},{"v":1.49095420749196e-13,"d":"1.49E-13"},-0.175579720965291,19.5646145753226,"Up"]
[1893,"REACTOME_DOWNREGULATION_OF_TGF_BETA_RECEPTOR_SIGNALING",7.39733024921629,0.052109026186848,{"v":3.60756390691697e-13,"d":"3.61E-13"},{"v":1.47394058410137e-13,"d":"1.47E-13"},-0.198959344346098,19.5758689845993,"Up"]
[1894,"REACTOME_SHC1_EVENTS_IN_ERBB2_SIGNALING",7.39824081275446,0.0489567006172286,{"v":3.58598157008305e-13,"d":"3.59E-13"},{"v":1.4639128541837e-13,"d":"1.46E-13"},-0.204594831685712,19.5825633128667,"Up"]
[1895,"REACTOME_DSCAM_INTERACTIONS",7.39994899716591,0.060685472376524,{"v":3.54327132754936e-13,"d":"3.54E-13"},{"v":1.44528172571092e-13,"d":"1.45E-13"},-0.0891417760792585,19.5951238359001,"Up"]
[1896,"REACTOME_G1_S_DNA_DAMAGE_CHECKPOINTS",7.40569254268583,0.0489143534766009,{"v":3.39665049959683e-13,"d":"3.40E-13"},{"v":1.384329893223e-13,"d":"1.38E-13"},-0.18514880439347,19.6373780327401,"Up"]
[1897,"REACTOME_CA2_ACTIVATED_K_CHANNELS",7.41425029016136,0.0375026529444735,{"v":3.19053036962078e-13,"d":"3.19E-13"},{"v":1.29817126375258e-13,"d":"1.30E-13"},0.387746882221985,19.7003960953426,"Up"]
[1898,"BIOCARTA_ALK_PATHWAY",7.42095699654704,0.0363582596352363,{"v":3.0361999524254e-13,"d":"3.04E-13"},{"v":1.23435254476134e-13,"d":"1.23E-13"},-0.199636223779083,19.7498337915115,"Up"]
[1899,"REACTOME_REGULATION_OF_CYTOSKELETAL_REMODELING_AND_CELL_SPREADING_BY_IPP_COMPLEX_COMPONENTS",7.42329396003811,0.0643130547486315,{"v":2.98578063918505e-13,"d":"2.99E-13"},{"v":1.2128474661197e-13,"d":"1.21E-13"},-0.21828672484728,19.7670708561227,"Up"]
[1900,"REACTOME_CALNEXIN_CALRETICULIN_CYCLE",7.43645525320076,0.0499412828865114,{"v":2.70637579558204e-13,"d":"2.71E-13"},{"v":1.09843794942145e-13,"d":"1.10E-13"},-0.236159973273247,19.86424692612,"Up"]
[1901,"WP_MED_AND_PSEUDOACHONDROPLASIA_GENES",7.44175661778884,0.0337949829208343,{"v":2.60253086529976e-13,"d":"2.60E-13"},{"v":1.05541231447042e-13,"d":"1.06E-13"},0.332067574713632,19.9034376390966,"Up"]
[1902,"PID_RHOA_REG_PATHWAY",7.44676604029285,0.0336533477780964,{"v":2.508122382646e-13,"d":"2.51E-13"},{"v":1.01628035815042e-13,"d":"1.02E-13"},-0.136654268138226,19.940495597142,"Up"]
[1903,"WP_HEREDITARY_LEIOMYOMATOSIS_AND_RENAL_CELL_CARCINOMA_PATHWAY",7.44866247994798,0.0529171110867434,{"v":2.47454773891556e-13,"d":"2.47E-13"},{"v":1.00184118984436e-13,"d":"1.00E-13"},-0.267913103895263,19.9545312476935,"Up"]
[1904,"BIOCARTA_INFLAM_PATHWAY",7.45474941519608,0.0339601683903438,{"v":2.36537888574383e-13,"d":"2.37E-13"},{"v":9.5684523751918e-14,"d":"9.57E-14"},0.168372076565184,19.9996049194387,"Up"]
[1905,"WP_OVARIAN_INFERTILITY",7.45676075700482,0.0387855624660319,{"v":2.33165921876071e-13,"d":"2.33E-13"},{"v":9.42418267231892e-14,"d":"9.42E-14"},-0.115909927130902,20.014506902543,"Up"]
[1906,"REACTOME_CELL_CYCLE_MITOTIC",7.46740229082658,0.0252371810111022,{"v":2.15503261020344e-13,"d":"2.16E-13"},{"v":8.69574562011914e-14,"d":"8.70E-14"},-0.154413897611183,20.0934161044587,"Up"]
[1907,"WP_WHITE_FAT_CELL_DIFFERENTIATION",7.46830731526125,0.0451772981181524,{"v":2.14211933610787e-13,"d":"2.14E-13"},{"v":8.63641230313397e-14,"d":"8.64E-14"},-0.146858245705775,20.1001321982749,"Up"]
[1908,"BIOCARTA_IL22BP_PATHWAY",7.46851504369803,0.0633905442617008,{"v":2.14054665986462e-13,"d":"2.14E-13"},{"v":8.62284990512265e-14,"d":"8.62E-14"},-0.187522058489282,20.1016738436442,"Up"]
[1909,"WP_HEART_DEVELOPMENT",7.47938666002129,0.0339192685167296,{"v":1.9730673993047e-13,"d":"1.97E-13"},{"v":7.94152971447541e-14,"d":"7.94E-14"},-0.133060629383935,20.1824162943583,"Up"]
[1910,"REACTOME_METABOLISM_OF_FOLATE_AND_PTERINES",7.48402232238106,0.0375725899512345,{"v":1.90655157590578e-13,"d":"1.91E-13"},{"v":7.66737340917574e-14,"d":"7.67E-14"},0.00752285041292242,20.2168803265788,"Up"]
[1911,"WP_FLUOROACETIC_ACID_TOXICITY",7.48575583380786,0.0764534998889154,{"v":1.88323772318654e-13,"d":"1.88E-13"},{"v":7.56726089175157e-14,"d":"7.57E-14"},-0.284218354796171,20.2297736311808,"Up"]
[1912,"KEGG_SNARE_INTERACTIONS_IN_VESICULAR_TRANSPORT",7.48620536162747,0.0367800240516932,{"v":1.87840650940882e-13,"d":"1.88E-13"},{"v":7.54151061469802e-14,"d":"7.54E-14"},-0.27488588481814,20.2331175590145,"Up"]
[1913,"PID_CMYB_PATHWAY",7.48789832406686,0.0335753886321201,{"v":1.85600334702907e-13,"d":"1.86E-13"},{"v":7.44530357495806e-14,"d":"7.45E-14"},-0.172209503563277,20.24571288054,"Up"]
[1914,"REACTOME_NRIF_SIGNALS_CELL_DEATH_FROM_THE_NUCLEUS",7.48834283123557,0.0632480703842401,{"v":1.8513133852758e-13,"d":"1.85E-13"},{"v":7.42024393288681e-14,"d":"7.42E-14"},-0.166015429635365,20.2490203981452,"Up"]
[1915,"REACTOME_DISEASES_OF_PROGRAMMED_CELL_DEATH",7.49357585259217,0.0438148980692901,{"v":1.78074435167242e-13,"d":"1.78E-13"},{"v":7.13138847987572e-14,"d":"7.13E-14"},-0.144855379992524,20.287973236415,"Up"]
[1916,"REACTOME_RUNX3_REGULATES_IMMUNE_RESPONSE_AND_CELL_MIGRATION",7.49523465299972,0.0565666203531323,{"v":1.75994477819285e-13,"d":"1.76E-13"},{"v":7.04215420693902e-14,"d":"7.04E-14"},0.126908595302464,20.3003264161702,"Up"]
[1917,"PID_AR_NONGENOMIC_PATHWAY",7.50029641335532,0.0449199098982711,{"v":1.69500549693588e-13,"d":"1.70E-13"},{"v":6.77659080252704e-14,"d":"6.78E-14"},-0.152326478067511,20.3380383865657,"Up"]
[1918,"REACTOME_APOPTOTIC_FACTOR_MEDIATED_RESPONSE",7.50205546716032,0.0484263915134951,{"v":1.6739160244956e-13,"d":"1.67E-13"},{"v":6.68662811404449e-14,"d":"6.69E-14"},-0.227576940621024,20.3511498924475,"Up"]
[1919,"WP_WNT_SIGNALING_PATHWAY",7.51162458571348,0.0352789706028092,{"v":1.55777220224314e-13,"d":"1.56E-13"},{"v":6.21742414053181e-14,"d":"6.22E-14"},-0.200308682449691,20.4225288801462,"Up"]
[1920,"BIOCARTA_BOTULIN_PATHWAY",7.51696304667258,0.144697969947791,{"v":1.497018434795e-13,"d":"1.50E-13"},{"v":5.96989132904079e-14,"d":"5.97E-14"},-0.0635854126510794,20.4623892966038,"Up"]
[1921,"PID_ERBB2_ERBB3_PATHWAY",7.51745660272538,0.041558141667926,{"v":1.49266680753801e-13,"d":"1.49E-13"},{"v":5.94750168590552e-14,"d":"5.95E-14"},-0.226823962047372,20.4660759244168,"Up"]
[1922,"WP_NUCLEOTIDE_GPCRS",7.51766116422164,0.0581344525823304,{"v":1.49160692488142e-13,"d":"1.49E-13"},{"v":5.938246192173e-14,"d":"5.94E-14"},-0.0950166407475017,20.4676039713597,"Up"]
[1923,"REACTOME_SIGNALING_BY_NOTCH2",7.52233484093669,0.046135127658774,{"v":1.44066979106246e-13,"d":"1.44E-13"},{"v":5.730599472546e-14,"d":"5.73E-14"},-0.218629433131513,20.5025269395021,"Up"]
[1924,"BIOCARTA_NEUTROPHIL_PATHWAY",7.52806171117193,0.0628353787264339,{"v":1.38031698976125e-13,"d":"1.38E-13"},{"v":5.48587521571778e-14,"d":"5.49E-14"},0.17280872352956,20.5453489898975,"Up"]
[1925,"REACTOME_NEGATIVE_REGULATORS_OF_DDX58_IFIH1_SIGNALING",7.52903021972028,0.0458184203628217,{"v":1.37132639916991e-13,"d":"1.37E-13"},{"v":5.44551677403165e-14,"d":"5.45E-14"},-0.217512999348081,20.5525941013016,"Up"]
[1926,"BIOCARTA_RHO_PATHWAY",7.5312321837799,0.0562693975427953,{"v":1.34963891411765e-13,"d":"1.35E-13"},{"v":5.35484265520361e-14,"d":"5.35E-14"},-0.235167317147837,20.5690697484943,"Up"]
[1927,"REACTOME_TRANSCRIPTIONAL_REGULATION_BY_RUNX2",7.53644806023861,0.0402702360245687,{"v":1.29809098912179e-13,"d":"1.30E-13"},{"v":5.1459409993863e-14,"d":"5.15E-14"},-0.169255456945,20.6081153001746,"Up"]
[1928,"KEGG_ALZHEIMERS_DISEASE",7.53815340564622,0.0509267947362397,{"v":1.28239568111496e-13,"d":"1.28E-13"},{"v":5.07939449942296e-14,"d":"5.08E-14"},-0.147223749057213,20.6208871658884,"Up"]
[1929,"REACTOME_TICAM1_RIP1_MEDIATED_IKK_COMPLEX_RECRUITMENT",7.53908021528285,0.0601968725042785,{"v":1.27444013471462e-13,"d":"1.27E-13"},{"v":5.04358393394145e-14,"d":"5.04E-14"},-0.155205423448165,20.627829534954,"Up"]
[1930,"REACTOME_P75_NTR_RECEPTOR_MEDIATED_SIGNALLING",7.5399560846784,0.0313662670021467,{"v":1.26702650498081e-13,"d":"1.27E-13"},{"v":5.00996985100374e-14,"d":"5.01E-14"},-0.187174481677245,20.634391108208,"Up"]
[1931,"WP_P38_MAPK_SIGNALING_PATHWAY",7.5409639166478,0.0424138904504957,{"v":1.25838729449113e-13,"d":"1.26E-13"},{"v":4.97156383889716e-14,"d":"4.97E-14"},-0.255844695481425,20.6419422137546,"Up"]
[1932,"KEGG_PATHOGENIC_ESCHERICHIA_COLI_INFECTION",7.54159245692639,0.0559053886962758,{"v":1.25343213876786e-13,"d":"1.25E-13"},{"v":4.9477584425047e-14,"d":"4.95E-14"},-0.159377714981616,20.6466520112797,"Up"]
[1933,"WP_PATHOGENIC_ESCHERICHIA_COLI_INFECTION",7.54159245692639,0.0559053886962758,{"v":1.25343213876786e-13,"d":"1.25E-13"},{"v":4.9477584425047e-14,"d":"4.95E-14"},-0.159377714981616,20.6466520112797,"Up"]
[1934,"KEGG_COMPLEMENT_AND_COAGULATION_CASCADES",7.54480081325837,0.0277056523835195,{"v":1.22518267585785e-13,"d":"1.23E-13"},{"v":4.82798031512136e-14,"d":"4.83E-14"},0.0987818033747044,20.6706990294228,"Up"]
[1935,"REACTOME_DCC_MEDIATED_ATTRACTIVE_SIGNALING",7.55789060676348,0.0609227096730095,{"v":1.1094440726156e-13,"d":"1.11E-13"},{"v":4.36815530614849e-14,"d":"4.37E-14"},-0.186581423782211,20.7689136826653,"Up"]
[1936,"BIOCARTA_PPARA_PATHWAY",7.56130568673715,0.0399781663981296,{"v":1.08174610792216e-13,"d":"1.08E-13"},{"v":4.25545196301363e-14,"d":"4.26E-14"},-0.201766909606454,20.794565291418,"Up"]
[1937,"REACTOME_RNA_POLYMERASE_III_TRANSCRIPTION_INITIATION_FROM_TYPE_3_PROMOTER",7.561750233034,0.0439669834181391,{"v":1.07899603235372e-13,"d":"1.08E-13"},{"v":4.2409931770988e-14,"d":"4.24E-14"},-0.239815949967198,20.7979052464063,"Up"]
[1938,"WP_VITAMIN_D_RECEPTOR_PATHWAY",7.56420680864894,0.0235268356441975,{"v":1.05979816654871e-13,"d":"1.06E-13"},{"v":4.16196041114271e-14,"d":"4.16E-14"},-0.0850373922377756,20.8163654434829,"Up"]
[1939,"REACTOME_CHROMOSOME_MAINTENANCE",7.56504109131336,0.0294782247917227,{"v":1.05395324697777e-13,"d":"1.05E-13"},{"v":4.13545083075284e-14,"d":"4.14E-14"},-0.156963626301777,20.8226361008309,"Up"]
[1940,"WP_IL3_SIGNALING_PATHWAY",7.57358594379658,0.0363756839512081,{"v":9.87996031075729e-14,"d":"9.88E-14"},{"v":3.87331777365046e-14,"d":"3.87E-14"},-0.158365697545274,20.8869006143756,"Up"]
[1941,"REACTOME_MITOTIC_METAPHASE_AND_ANAPHASE",7.58308807813622,0.0329699538818893,{"v":9.19320840727179e-14,"d":"9.19E-14"},{"v":3.60098345507508e-14,"d":"3.60E-14"},-0.157787259406896,20.9584491458745,"Up"]
[1942,"REACTOME_TGF_BETA_RECEPTOR_SIGNALING_IN_EMT_EPITHELIAL_TO_MESENCHYMAL_TRANSITION",7.58619153211123,0.0650851810142685,{"v":8.98446222841465e-14,"d":"8.98E-14"},{"v":3.51618629722031e-14,"d":"3.52E-14"},-0.164625817354718,20.981836589635,"Up"]
[1943,"REACTOME_RECRUITMENT_OF_MITOTIC_CENTROSOME_PROTEINS_AND_COMPLEXES",7.59118154018097,0.0354041597601971,{"v":8.65401584073192e-14,"d":"8.65E-14"},{"v":3.38394209156825e-14,"d":"3.38E-14"},-0.160241547096117,21.0194608801149,"Up"]
[1944,"REACTOME_INTERLEUKIN_18_SIGNALING",7.59876086928153,0.0985199579851153,{"v":8.17117209168355e-14,"d":"8.17E-14"},{"v":3.19238099938244e-14,"d":"3.19E-14"},0.0559607411069494,21.0766553711528,"Up"]
[1945,"REACTOME_SODIUM_COUPLED_PHOSPHATE_COTRANSPORTERS",7.60025799497857,0.0827885378962891,{"v":8.08458304638744e-14,"d":"8.08E-14"},{"v":3.15582408389685e-14,"d":"3.16E-14"},-0.132755396853078,21.087959545522,"Up"]
[1946,"WP_OVERLAP_BETWEEN_SIGNAL_TRANSDUCTION_PATHWAYS_CONTRIBUTING_TO_LMNA_LAMINOPATHIES",7.6007700391148,0.036628875878739,{"v":8.05976136561837e-14,"d":"8.06E-14"},{"v":3.14341570130055e-14,"d":"3.14E-14"},-0.19928146373728,21.0918262847239,"Up"]
[1947,"REACTOME_TRANS_GOLGI_NETWORK_VESICLE_BUDDING",7.60169304833972,0.0367283472514738,{"v":8.0165913063035e-14,"d":"8.02E-14"},{"v":3.12116948970116e-14,"d":"3.12E-14"},-0.20720344687848,21.0987971094542,"Up"]
[1948,"REACTOME_ABERRANT_REGULATION_OF_MITOTIC_G1_S_TRANSITION_IN_CANCER_DUE_TO_RB1_DEFECTS",7.60688055107362,0.0514866002192181,{"v":7.70946477460404e-14,"d":"7.71E-14"},{"v":2.99899220145697e-14,"d":"3.00E-14"},-0.238334477119765,21.1379901946044,"Up"]
[1949,"REACTOME_DEGRADATION_OF_BETA_CATENIN_BY_THE_DESTRUCTION_COMPLEX",7.60932002188944,0.0472365977416116,{"v":7.5725454872358e-14,"d":"7.57E-14"},{"v":2.94317557398638e-14,"d":"2.94E-14"},-0.186720428409413,21.1564302645011,"Up"]
[1950,"REACTOME_SUMO_IS_CONJUGATED_TO_E1_UBA2_SAE1",7.61048277981375,0.090515325409595,{"v":7.51154285892043e-14,"d":"7.51E-14"},{"v":2.91693179170628e-14,"d":"2.92E-14"},-0.251167143007552,21.1652216665024,"Up"]
[1951,"REACTOME_CELL_DEATH_SIGNALLING_VIA_NRAGE_NRIF_AND_NADE",7.61781174776495,0.0315349318895917,{"v":7.11136470707163e-14,"d":"7.11E-14"},{"v":2.75673348462392e-14,"d":"2.76E-14"},-0.171531934976428,21.2206653096846,"Up"]
[1952,"REACTOME_RA_BIOSYNTHESIS_PATHWAY",7.61798907245344,0.0464210011284186,{"v":7.10783391802923e-14,"d":"7.11E-14"},{"v":2.75296671319081e-14,"d":"2.75E-14"},-0.0736568609865741,21.2220074263606,"Up"]
[1953,"REACTOME_RUNX2_REGULATES_GENES_INVOLVED_IN_CELL_MIGRATION",7.62640158293472,0.055750698477281,{"v":6.66697561649317e-14,"d":"6.67E-14"},{"v":2.5799666100262e-14,"d":"2.58E-14"},-0.170635333527119,21.2857147418406,"Up"]
[1954,"REACTOME_INTERLEUKIN_1_SIGNALING",7.62667836321255,0.0441263450053331,{"v":6.65855179901869e-14,"d":"6.66E-14"},{"v":2.57446031095662e-14,"d":"2.57E-14"},-0.167298307425052,21.2878119624455,"Up"]
[1955,"BIOCARTA_P38MAPK_PATHWAY",7.63343998464664,0.0420223461743215,{"v":6.32529910228608e-14,"d":"6.33E-14"},{"v":2.44347755469553e-14,"d":"2.44E-14"},-0.246525331834236,21.3390695789681,"Up"]
[1956,"REACTOME_DAP12_SIGNALING",7.64218800762701,0.0463369389232344,{"v":5.91686780627698e-14,"d":"5.92E-14"},{"v":2.2837033638262e-14,"d":"2.28E-14"},-0.125655930827294,21.4054522510095,"Up"]
[1957,"WP_TRANSCRIPTIONAL_ACTIVATION_BY_NRF2_IN_RESPONSE_TO_PHYTOCHEMICALS",7.64785818888927,0.0539686358085891,{"v":5.66785352943792e-14,"d":"5.67E-14"},{"v":2.18568035902414e-14,"d":"2.19E-14"},-0.171344574883591,21.448519570358,"Up"]
[1958,"REACTOME_TCF_DEPENDENT_SIGNALING_IN_RESPONSE_TO_WNT",7.649934465893,0.033355599288613,{"v":5.58236991098016e-14,"d":"5.58E-14"},{"v":2.15083213169344e-14,"d":"2.15E-14"},-0.175583937971775,21.4642976523098,"Up"]
[1959,"PID_IL12_2PATHWAY",7.65235945443132,0.0275238767020104,{"v":5.4833291855831e-14,"d":"5.48E-14"},{"v":2.1108227397943e-14,"d":"2.11E-14"},-0.0249255296586315,21.4827310433088,"Up"]
[1960,"WP_COPPER_HOMEOSTASIS",7.66212812318951,0.0364845789585987,{"v":5.08803293739e-14,"d":"5.09E-14"},{"v":1.95693574515e-14,"d":"1.96E-14"},-0.222768846212373,21.557045579916,"Up"]
[1961,"REACTOME_AMYLOID_FIBER_FORMATION",7.66382532926757,0.0468754964331743,{"v":5.02591580660536e-14,"d":"5.03E-14"},{"v":1.93134888789592e-14,"d":"1.93E-14"},-0.163071497782592,21.5699665493678,"Up"]
[1962,"REACTOME_ATTENUATION_PHASE",7.67382194816485,0.0623333641039623,{"v":4.65894210163179e-14,"d":"4.66E-14"},{"v":1.78718527987697e-14,"d":"1.79E-14"},-0.174296796377756,21.6461291803232,"Up"]
[1963,"REACTOME_AUTOPHAGY",7.67729142015503,0.0365025544796446,{"v":4.53906695873751e-14,"d":"4.54E-14"},{"v":1.73966938769427e-14,"d":"1.74E-14"},-0.170138178248532,21.6725855291185,"Up"]
[1964,"REACTOME_ZBP1_DAI_MEDIATED_INDUCTION_OF_TYPE_I_IFNS",7.68353770000849,0.0458848142147596,{"v":4.32779787260475e-14,"d":"4.33E-14"},{"v":1.65723703961079e-14,"d":"1.66E-14"},-0.26390982642261,21.7202462134467,"Up"]
[1965,"REACTOME_DEUBIQUITINATION",7.68705485755573,0.0307974592658182,{"v":4.21474810295662e-14,"d":"4.21E-14"},{"v":1.6125250839247e-14,"d":"1.61E-14"},-0.209494844550538,21.7470999134155,"Up"]
[1966,"REACTOME_HYALURONAN_BIOSYNTHESIS_AND_EXPORT",7.69524482125618,0.0585340485992579,{"v":3.96149278860619e-14,"d":"3.96E-14"},{"v":1.51295878431249e-14,"d":"1.51E-14"},0.0095795905057594,21.8096779553159,"Up"]
[1967,"WP_THYROID_HORMONES_PRODUCTION_AND_PERIPHERAL_DOWNSTREAM_SIGNALING_EFFECTS",7.69558285761169,0.023970318329256,{"v":3.95457332069663e-14,"d":"3.95E-14"},{"v":1.50898192500266e-14,"d":"1.51E-14"},-0.156680885677397,21.8122622494619,"Up"]
[1968,"REACTOME_PCP_CE_PATHWAY",7.69869077922415,0.0483405113748699,{"v":3.86342240415494e-14,"d":"3.86E-14"},{"v":1.47289720536271e-14,"d":"1.47E-14"},-0.156180153953467,21.8360276391297,"Up"]
[1969,"REACTOME_ABACAVIR_METABOLISM",7.70252324306157,0.108223455679863,{"v":3.75308969187052e-14,"d":"3.75E-14"},{"v":1.42956756481843e-14,"d":"1.43E-14"},-0.143125618171867,21.8653464895016,"Up"]
[1970,"PID_MYC_PATHWAY",7.73560108545487,0.0453359015862144,{"v":2.90129693168068e-14,"d":"2.90E-14"},{"v":1.10413729383799e-14,"d":"1.10E-14"},-0.263458247266611,22.1189972748465,"Up"]
[1971,"REACTOME_REGULATION_OF_RUNX1_EXPRESSION_AND_ACTIVITY",7.74079261167561,0.0513416219548896,{"v":2.78823069144479e-14,"d":"2.79E-14"},{"v":1.06016733780643e-14,"d":"1.06E-14"},-0.293139135846136,22.1589052378082,"Up"]
[1972,"REACTOME_PLASMA_LIPOPROTEIN_CLEARANCE",7.74241764131979,0.0430570446299751,{"v":2.7578678518131e-14,"d":"2.76E-14"},{"v":1.04676158343108e-14,"d":"1.05E-14"},-0.0936657678456785,22.1714025119254,"Up"]
[1973,"WP_EXTRACELLULAR_VESICLEMEDIATED_SIGNALING_IN_RECIPIENT_CELLS",7.74483522037349,0.0395918515864509,{"v":2.70854176720328e-14,"d":"2.71E-14"},{"v":1.02712582534969e-14,"d":"1.03E-14"},-0.196477687666718,22.1899996894077,"Up"]
[1974,"REACTOME_REGULATION_OF_PTEN_STABILITY_AND_ACTIVITY",7.74567141937558,0.0530780038034825,{"v":2.69325164879366e-14,"d":"2.69E-14"},{"v":1.02041889392553e-14,"d":"1.02E-14"},-0.195311733921581,22.1964334722319,"Up"]
[1975,"REACTOME_SIGNALING_BY_ERBB2",7.74734124753019,0.0460062412774827,{"v":2.66061098572204e-14,"d":"2.66E-14"},{"v":1.00715436099195e-14,"d":"1.01E-14"},-0.192298606086124,22.2092833247662,"Up"]
[1976,"REACTOME_FCERI_MEDIATED_NF_KB_ACTIVATION",7.74904456105861,0.0467783748612741,{"v":2.62767111858473e-14,"d":"2.63E-14"},{"v":9.9379869228525e-15,"d":"9.94E-15"},-0.170868863147456,22.2223936854873,"Up"]
[1977,"REACTOME_REGULATION_OF_MRNA_STABILITY_BY_PROTEINS_THAT_BIND_AU_RICH_ELEMENTS",7.74968778426523,0.0495898839408904,{"v":2.61679030558439e-14,"d":"2.62E-14"},{"v":9.88800655281552e-15,"d":"9.89E-15"},-0.200084062675261,22.227345300913,"Up"]
[1978,"PID_REELIN_PATHWAY",7.75231418590163,0.0427149928620207,{"v":2.56574912841215e-14,"d":"2.57E-14"},{"v":9.68648203337784e-15,"d":"9.69E-15"},-0.204410776086505,22.2475679066567,"Up"]
[1979,"WP_LUNG_FIBROSIS",7.75665762033129,0.027214494774085,{"v":2.48203027300236e-14,"d":"2.48E-14"},{"v":9.36204401220188e-15,"d":"9.36E-15"},0.0326687990160195,22.2810261147188,"Up"]
[1980,"REACTOME_PI3K_AKT_ACTIVATION",7.76332033224698,0.0697363900259778,{"v":2.35767802871078e-14,"d":"2.36E-14"},{"v":8.88504169389317e-15,"d":"8.89E-15"},-0.192798976569838,22.3323861975914,"Up"]
[1981,"BIOCARTA_RAN_PATHWAY",7.76555120420449,0.0928769882500365,{"v":2.31880864222078e-14,"d":"2.32E-14"},{"v":8.73073699297705e-15,"d":"8.73E-15"},-0.256174922135708,22.3495928284375,"Up"]
[1982,"REACTOME_RHO_GTPASES_ACTIVATE_PAKS",7.77427014892759,0.0697237797522855,{"v":2.16913775864631e-14,"d":"2.17E-14"},{"v":8.15256229126853e-15,"d":"8.15E-15"},-0.17000492044519,22.4168887020329,"Up"]
[1983,"PID_MTOR_4PATHWAY",7.78078868306186,0.0422394888807452,{"v":2.06257234392606e-14,"d":"2.06E-14"},{"v":7.74508440887213e-15,"d":"7.75E-15"},-0.212099511602411,22.4672499145536,"Up"]
[1984,"WP_HEMATOPOIETIC_STEM_CELL_DIFFERENTIATION",7.78380148119251,0.0270213013120813,{"v":2.01605088438887e-14,"d":"2.02E-14"},{"v":7.56359171201221e-15,"d":"7.56E-15"},0.0984624645683118,22.4905404701579,"Up"]
[1985,"WP_PYRIMIDINE_METABOLISM",7.78772321128609,0.0311901670992564,{"v":1.95650775997379e-14,"d":"1.96E-14"},{"v":7.33360364821483e-15,"d":"7.33E-15"},-0.143244630158364,22.5208709430899,"Up"]
[1986,"REACTOME_TRANSCRIPTION_COUPLED_NUCLEOTIDE_EXCISION_REPAIR_TC_NER",7.79138102050703,0.0378485450540685,{"v":1.90264893518963e-14,"d":"1.90E-14"},{"v":7.12530471680328e-15,"d":"7.13E-15"},-0.233208095500725,22.549173907531,"Up"]
[1987,"REACTOME_AURKA_ACTIVATION_BY_TPX2",7.79464350417395,0.0375411378228725,{"v":1.85602498441777e-14,"d":"1.86E-14"},{"v":6.94443895991669e-15,"d":"6.94E-15"},-0.143227005321993,22.5744290784714,"Up"]
[1988,"KEGG_NUCLEOTIDE_EXCISION_REPAIR",7.79949764073462,0.0381116893899812,{"v":1.78794180282652e-14,"d":"1.79E-14"},{"v":6.68366908748915e-15,"d":"6.68E-15"},-0.22158650240415,22.6120247608106,"Up"]
[1989,"REACTOME_FOXO_MEDIATED_TRANSCRIPTION_OF_CELL_CYCLE_GENES",7.81269932204905,0.0586354098640165,{"v":1.6124571284304e-14,"d":"1.61E-14"},{"v":6.02223360719452e-15,"d":"6.02E-15"},-0.276447042949805,22.7143901476042,"Up"]
[1990,"KEGG_RNA_POLYMERASE",7.81668125386531,0.0503674849099817,{"v":1.56392377843236e-14,"d":"1.56E-14"},{"v":5.83569399104653e-15,"d":"5.84E-15"},-0.181476251802121,22.7452995791558,"Up"]
[1991,"REACTOME_APC_C_MEDIATED_DEGRADATION_OF_CELL_CYCLE_PROTEINS",7.81962872536254,0.046629151145974,{"v":1.52928726032661e-14,"d":"1.53E-14"},{"v":5.70129022490183e-15,"d":"5.70E-15"},-0.168997178106187,22.7681891435914,"Up"]
[1992,"REACTOME_CITRIC_ACID_CYCLE_TCA_CYCLE",7.8261684274789,0.0479038937461889,{"v":1.45350610572383e-14,"d":"1.45E-14"},{"v":5.41386889581345e-15,"d":"5.41E-15"},-0.32427165178572,22.8190058897757,"Up"]
[1993,"WP_QUERCETIN_AND_NFKB_AP1_INDUCED_APOPTOSIS",7.83160969305729,0.0652263101266203,{"v":1.39349253734885e-14,"d":"1.39E-14"},{"v":5.18563518453369e-15,"d":"5.19E-15"},-0.176379653752689,22.8613193120517,"Up"]
[1994,"REACTOME_EPHB_MEDIATED_FORWARD_SIGNALING",7.83351944484411,0.0558166076981432,{"v":1.37382157797992e-14,"d":"1.37E-14"},{"v":5.10779817454073e-15,"d":"5.11E-15"},-0.1730688364294,22.8761772006198,"Up"]
[1995,"KEGG_TGF_BETA_SIGNALING_PATHWAY",7.84000086374242,0.0284689285339216,{"v":1.30623561217255e-14,"d":"1.31E-14"},{"v":4.85211001687577e-15,"d":"4.85E-15"},-0.161058759020063,22.926629464927,"Up"]
[1996,"REACTOME_MTORC1_MEDIATED_SIGNALLING",7.84117811839391,0.0592673388254533,{"v":1.2952786987431e-14,"d":"1.30E-14"},{"v":4.80703970518694e-15,"d":"4.81E-15"},-0.180100672892059,22.9357978145042,"Up"]
[1997,"BIOCARTA_TID_PATHWAY",7.84339305713604,0.0551822862201701,{"v":1.27388807015579e-14,"d":"1.27E-14"},{"v":4.72335691329694e-15,"d":"4.72E-15"},-0.227172179106644,22.953051247727,"Up"]
[1998,"PID_INSULIN_PATHWAY",7.84744410270625,0.0371455706654013,{"v":1.2347295809417e-14,"d":"1.23E-14"},{"v":4.57399824518891e-15,"d":"4.57E-15"},-0.26878029865169,22.9846196628125,"Up"]
[1999,"REACTOME_VITAMIN_B2_RIBOFLAVIN_METABOLISM",7.8501059442297,0.0522071381458896,{"v":1.21002533727167e-14,"d":"1.21E-14"},{"v":4.4784001180399e-15,"d":"4.48E-15"},-0.11891979445915,23.0053712761277,"Up"]
[2000,"BIOCARTA_ARF_PATHWAY",7.86311267079216,0.0535046131309592,{"v":1.09325352609401e-14,"d":"1.09E-14"},{"v":4.03884146785743e-15,"d":"4.04E-15"},-0.169773974958959,23.1068714745286,"Up"]
[2001,"REACTOME_ANTIVIRAL_MECHANISM_BY_IFN_STIMULATED_GENES",7.86760965474709,0.0367366181369793,{"v":1.05678371618445e-14,"d":"1.06E-14"},{"v":3.89697908835898e-15,"d":"3.90E-15"},-0.234416904125486,23.1420031762416,"Up"]
[2002,"REACTOME_CLATHRIN_MEDIATED_ENDOCYTOSIS",7.86876924917685,0.0340023865196097,{"v":1.0480403584956e-14,"d":"1.05E-14"},{"v":3.86120132077325e-15,"d":"3.86E-15"},-0.164807987454497,23.1510654804846,"Up"]
[2003,"PID_TRKR_PATHWAY",7.87110215964087,0.0377930247827786,{"v":1.02971139587574e-14,"d":"1.03E-14"},{"v":3.79019950371266e-15,"d":"3.79E-15"},-0.183187117538119,23.1693013323954,"Up"]
[2004,"WP_APOPTOSIS_MODULATION_AND_SIGNALING",7.87266368113182,0.0308924360752987,{"v":1.01792860533372e-14,"d":"1.02E-14"},{"v":3.74339466873736e-15,"d":"3.74E-15"},-0.205970984939736,23.1815103966865,"Up"]
[2005,"REACTOME_GP1B_IX_V_ACTIVATION_SIGNALLING",7.87658610273442,0.0706176405149826,{"v":9.87542801044352e-15,"d":"9.88E-15"},{"v":3.62832021031478e-15,"d":"3.63E-15"},-0.171312992732779,23.2121892066835,"Up"]
[2006,"REACTOME_REGULATION_OF_RUNX2_EXPRESSION_AND_ACTIVITY",7.88177135048297,0.0537474156583341,{"v":9.49333138654981e-15,"d":"9.49E-15"},{"v":3.48152875073537e-15,"d":"3.48E-15"},-0.178968669061256,23.2527683108907,"Up"]
[2007,"REACTOME_ORGANIC_CATION_ANION_ZWITTERION_TRANSPORT",7.88711847908733,0.0568975666864711,{"v":9.10564932895721e-15,"d":"9.11E-15"},{"v":3.33628042214829e-15,"d":"3.34E-15"},0.128788250612327,23.2946419786169,"Up"]
[2008,"REACTOME_ORGANIC_CATION_TRANSPORT",7.88711847908733,0.0568975666864711,{"v":9.10564932895721e-15,"d":"9.11E-15"},{"v":3.33628042214829e-15,"d":"3.34E-15"},0.128788250612327,23.2946419786169,"Up"]
[2009,"WP_TOLLLIKE_RECEPTOR_SIGNALING_RELATED_TO_MYD88",7.88714202393527,0.0402354387899047,{"v":9.10564932895721e-15,"d":"9.11E-15"},{"v":3.33565423933423e-15,"d":"3.34E-15"},-0.17875022933702,23.2948264218622,"Up"]
[2010,"REACTOME_NR1H2_NR1H3_REGULATE_GENE_EXPRESSION_LINKED_TO_LIPOGENESIS",7.89015042404426,0.0723509603670173,{"v":8.91277183247439e-15,"d":"8.91E-15"},{"v":3.25658970801949e-15,"d":"3.26E-15"},-0.268594282074224,23.3183978087658,"Up"]
[2011,"REACTOME_ADENYLATE_CYCLASE_ACTIVATING_PATHWAY",7.89302649140144,0.0596328009857889,{"v":8.71867919917163e-15,"d":"8.72E-15"},{"v":3.18272972115509e-15,"d":"3.18E-15"},0.0441790405969944,23.3409406685037,"Up"]
[2012,"PID_DNA_PK_PATHWAY",7.89461682685376,0.0578639280809403,{"v":8.61671084821575e-15,"d":"8.62E-15"},{"v":3.1425993343189e-15,"d":"3.14E-15"},-0.130239783023266,23.3534093466104,"Up"]
[2013,"KEGG_AMINO_SUGAR_AND_NUCLEOTIDE_SUGAR_METABOLISM",7.91172335430261,0.034265451124659,{"v":7.53710181505984e-15,"d":"7.54E-15"},{"v":2.74122663854066e-15,"d":"2.74E-15"},-0.17712470760981,23.4876866679259,"Up"]
[2014,"REACTOME_DEATH_RECEPTOR_SIGNALLING",7.91276123824445,0.0296196003161543,{"v":7.48174593625634e-15,"d":"7.48E-15"},{"v":2.71856962663565e-15,"d":"2.72E-15"},-0.182592875711725,23.4958427786861,"Up"]
[2015,"REACTOME_ESTROGEN_DEPENDENT_NUCLEAR_EVENTS_DOWNSTREAM_OF_ESR_MEMBRANE_SIGNALING",7.91357490849454,0.0475904390250037,{"v":7.44012552534368e-15,"d":"7.44E-15"},{"v":2.70093625683866e-15,"d":"2.70E-15"},-0.257658258971165,23.5022376688199,"Up"]
[2016,"WP_HYPOTHESIZED_PATHWAYS_IN_PATHOGENESIS_OF_CARDIOVASCULAR_DISEASE",7.91491045377892,0.0478790046311301,{"v":7.36791670269762e-15,"d":"7.37E-15"},{"v":2.67223699574897e-15,"d":"2.67E-15"},-0.23645957001068,23.5127355506485,"Up"]
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[2086,"SIG_INSULIN_RECEPTOR_PATHWAY_IN_CARDIAC_MYOCYTES",8.18487656573399,0.050002820969575,{"v":8.82970530817961e-16,"d":"8.83E-16"},{"v":2.976003914599e-16,"d":"2.98E-16"},-0.246242557175376,25.6707828334603,"Up"]
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[2128,"REACTOME_REGULATION_OF_TP53_ACTIVITY_THROUGH_ACETYLATION",8.36685006568346,0.0489427178042788,{"v":2.02339330192193e-16,"d":"2.02E-16"},{"v":6.51254119444509e-17,"d":"6.51E-17"},-0.303826943959494,27.1658528140554,"Up"]
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[2150,"REACTOME_OLFACTORY_SIGNALING_PATHWAY",8.46117245573113,0.0552230236510645,{"v":9.33428996228427e-17,"d":"9.33E-17"},{"v":2.92562596996022e-17,"d":"2.93E-17"},0.23604588152925499,27.9535912245867,"Up"]
[2151,"BIOCARTA_PDGF_PATHWAY",8.46851093410793,0.05148154466431,{"v":8.77714083936792e-17,"d":"8.78E-17"},{"v":2.74803869734596e-17,"d":"2.75E-17"},-0.225540029385918,28.0152451517228,"Up"]
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[2513,"REACTOME_MRNA_DECAY_BY_5_TO_3_EXORIBONUCLEASE",10.4714101988672,0.0821850958375693,{"v":8.21379502777277e-25,"d":"8.21E-25"},{"v":1.47427090242075e-25,"d":"1.47E-25"},-0.247331762522847,46.8134213512905,"Up"]
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[2515,"KEGG_INSULIN_SIGNALING_PATHWAY",10.4958667260679,0.0386598377705033,{"v":6.37922476147195e-25,"d":"6.38E-25"},{"v":1.14068458960193e-25,"d":"1.14E-25"},-0.205247261336868,47.0671571373952,"Up"]
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[2519,"PID_EPHRINB_REV_PATHWAY",10.5371677446319,0.0534737758468475,{"v":4.16237569748528e-25,"d":"4.16E-25"},{"v":7.38667212171815e-26,"d":"7.39E-26"},-0.115121688038905,47.4969753998135,"Up"]
[2520,"KEGG_AUTOIMMUNE_THYROID_DISEASE",10.5380673652105,0.062834563206703,{"v":4.13094216642386e-25,"d":"4.13E-25"},{"v":7.31695221785603e-26,"d":"7.32E-26"},0.0859205147130216,47.5063561888528,"Up"]
[2521,"KEGG_VIRAL_MYOCARDITIS",10.5409321761072,0.0561391012762941,{"v":4.01568203704755e-25,"d":"4.02E-25"},{"v":7.09924894538771e-26,"d":"7.10E-26"},-0.0845147056107255,47.536234236015,"Up"]
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[2532,"WP_INTEGRATED_CANCER_PATHWAY",10.6475787680159,0.0521337192582473,{"v":1.33011872151683e-25,"d":"1.33E-25"},{"v":2.29315339640723e-26,"d":"2.29E-26"},-0.23777062871264,48.6541665105254,"Up"]
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[2568,"BIOCARTA_G1_PATHWAY",10.8653482944872,0.0556452588449752,{"v":1.37607538668526e-26,"d":"1.38E-26"},{"v":2.20524901712382e-27,"d":"2.21E-27"},-0.219405824382714,50.9712966756324,"Up"]
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[2572,"PID_PDGFRB_PATHWAY",10.8820346207031,0.0547054701450377,{"v":1.16009424256498e-26,"d":"1.16E-26"},{"v":1.83955564779197e-27,"d":"1.84E-27"},-0.162794084391029,51.1507446305423,"Up"]
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[2579,"WP_BMP2WNT4FOXO1_PATHWAY_IN_PRIMARY_ENDOMETRIAL_STROMAL_CELL_DIFFERENTIATION",10.9227730721587,0.0927004499128095,{"v":7.57197870462628e-27,"d":"7.57E-27"},{"v":1.18024769282636e-27,"d":"1.18E-27"},-0.174111013217866,51.5899897866556,"Up"]
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[2584,"REACTOME_EGFR_INTERACTS_WITH_PHOSPHOLIPASE_C_GAMMA",10.9507787646064,0.100303044619676,{"v":5.64916033174231e-27,"d":"5.65E-27"},{"v":8.69101589498817e-28,"d":"8.69E-28"},-0.103018408097948,51.8928841167514,"Up"]
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[2643,"REACTOME_SIGNALING_BY_TGF_BETA_RECEPTOR_COMPLEX_IN_CANCER",11.3773174703065,0.0999819843854503,{"v":5.66100516204518e-29,"d":"5.66E-29"},{"v":7.48688941808945e-30,"d":"7.49E-30"},-0.312687135264017,56.6001530021973,"Up"]
[2644,"WP_OMEGA9_FATTY_ACID_SYNTHESIS",11.3836851293309,0.0784274485171776,{"v":5.27960698024035e-29,"d":"5.28E-29"},{"v":6.96466372899453e-30,"d":"6.96E-30"},-0.120834811672591,56.6717625793799,"Up"]
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[2648,"REACTOME_ACTIVATED_NOTCH1_TRANSMITS_SIGNAL_TO_THE_NUCLEUS",11.4037035581746,0.0722190768278209,{"v":4.24852974190009e-29,"d":"4.25E-29"},{"v":5.54716939984931e-30,"d":"5.55E-30"},-0.224060542727592,56.8971421732016,"Up"]
[2649,"REACTOME_SIGNALING_BY_RHO_GTPASES_MIRO_GTPASES_AND_RHOBTB3",11.4180810363577,0.0403508806771014,{"v":3.6258135391228e-29,"d":"3.63E-29"},{"v":4.70964309231538e-30,"d":"4.71E-30"},-0.169075646853459,57.0592520492427,"Up"]
[2650,"REACTOME_FOLDING_OF_ACTIN_BY_CCT_TRIC",11.4308305445325,0.136302486031799,{"v":3.14360532087472e-29,"d":"3.14E-29"},{"v":4.07268705538425e-30,"d":"4.07E-30"},-0.232639584689297,57.2031736312751,"Up"]
[2651,"REACTOME_DEFECTIVE_B4GALT1_CAUSES_B4GALT1_CDG_CDG_2D",11.4334828901737,0.0816851944027252,{"v":3.05790125477649e-29,"d":"3.06E-29"},{"v":3.95133664163089e-30,"d":"3.95E-30"},0.230329135446945,57.233134160154,"Up"]
[2652,"REACTOME_CA2_PATHWAY",11.4538340776732,0.0470950081762225,{"v":2.44310282933648e-29,"d":"2.44E-29"},{"v":3.13218311453395e-30,"d":"3.13E-30"},-0.0828181796641239,57.4632450549877,"Up"]
[2653,"REACTOME_CASPASE_ACTIVATION_VIA_DEATH_RECEPTORS_IN_THE_PRESENCE_OF_LIGAND",11.4620644941891,0.0752425214899076,{"v":2.22962727970443e-29,"d":"2.23E-29"},{"v":2.85097415319831e-30,"d":"2.85E-30"},-0.0568814163453353,57.5564202893808,"Up"]
[2654,"BIOCARTA_ACH_PATHWAY",11.4649626222357,0.0955672804355208,{"v":2.16265530233084e-29,"d":"2.16E-29"},{"v":2.75804218718306e-30,"d":"2.76E-30"},-0.181386879742467,57.5892451516099,"Up"]
[2655,"KEGG_T_CELL_RECEPTOR_SIGNALING_PATHWAY",11.4677391229365,0.04160795899345,{"v":2.10061323135868e-29,"d":"2.10E-29"},{"v":2.67183261883341e-30,"d":"2.67E-30"},-0.142835795186361,57.6207000632659,"Up"]
[2656,"REACTOME_CASPASE_ACTIVATION_VIA_EXTRINSIC_APOPTOTIC_SIGNALLING_PATHWAY",11.4742480198573,0.0609000617332539,{"v":1.95503909948468e-29,"d":"1.96E-29"},{"v":2.4800765904394e-30,"d":"2.48E-30"},-0.0699881584882142,57.6944684669299,"Up"]
[2657,"WP_CANONICAL_AND_NONCANONICAL_NOTCH_SIGNALING",11.4770617892673,0.0688614677862977,{"v":1.89812274718768e-29,"d":"1.90E-29"},{"v":2.40147108702895e-30,"d":"2.40E-30"},-0.184009515389656,57.726370945387,"Up"]
[2658,"REACTOME_SARS_COV_INFECTIONS",11.4937665523953,0.0552383997263295,{"v":1.5717140377095e-29,"d":"1.57E-29"},{"v":1.98320192342561e-30,"d":"1.98E-30"},-0.184204863923335,57.9159271729134,"Up"]
[2659,"REACTOME_SEMAPHORIN_INTERACTIONS",11.501893073415,0.0603021686531086,{"v":1.43955578249107e-29,"d":"1.44E-29"},{"v":1.80672992944223e-30,"d":"1.81E-30"},-0.127610004856435,58.0082400396856,"Up"]
[2660,"REACTOME_ROLE_OF_ABL_IN_ROBO_SLIT_SIGNALING",11.5094240225973,0.099536497092372,{"v":1.32393111791546e-29,"d":"1.32E-29"},{"v":1.65714724948258e-30,"d":"1.66E-30"},-0.161471052980243,58.0938446155221,"Up"]
[2661,"REACTOME_EXTRA_NUCLEAR_ESTROGEN_SIGNALING",11.5224206608585,0.0576906717521639,{"v":1.1434316069595e-29,"d":"1.14E-29"},{"v":1.42736064296563e-30,"d":"1.43E-30"},-0.161920787167442,58.2417070235262,"Up"]
[2662,"REACTOME_ESR_MEDIATED_SIGNALING",11.5294926045275,0.0497354528206254,{"v":1.05701448815653e-29,"d":"1.06E-29"},{"v":1.31591884659163e-30,"d":"1.32E-30"},-0.200867613328782,58.3222330358323,"Up"]
[2663,"REACTOME_MET_PROMOTES_CELL_MOTILITY",11.5295533593387,0.0641259020942861,{"v":1.05701448815653e-29,"d":"1.06E-29"},{"v":1.31499988759871e-30,"d":"1.31E-30"},-0.19216189454352,58.32292504163,"Up"]
[2664,"REACTOME_PROCESSING_AND_ACTIVATION_OF_SUMO",11.5298989276087,0.106380250910493,{"v":1.05701448815653e-29,"d":"1.06E-29"},{"v":1.30978503019336e-30,"d":"1.31E-30"},-0.187721523209246,58.3268611805234,"Up"]
[2665,"WP_ACUTE_VIRAL_MYOCARDITIS",11.5311938115737,0.0445918019164089,{"v":1.0450337626334e-29,"d":"1.05E-29"},{"v":1.29042630608578e-30,"d":"1.29E-30"},-0.159700618907621,58.3416113728074,"Up"]
[2666,"WP_MRNA_PROCESSING",11.5401333501397,0.0682159970086239,{"v":9.45484091509269e-30,"d":"9.45E-30"},{"v":1.16431070648071e-30,"d":"1.16E-30"},-0.199937768920131,58.4434871060467,"Up"]
[2667,"WP_THYROID_STIMULATING_HORMONE_TSH_SIGNALING_PATHWAY",11.5475091486265,0.0582278697513487,{"v":8.70901610294605e-30,"d":"8.71E-30"},{"v":1.06952829334425e-30,"d":"1.07E-30"},-0.205760551754444,58.527600568969,"Up"]
[2668,"REACTOME_SIGNALING_BY_INTERLEUKINS",11.553969018743,0.0416004675266237,{"v":8.10677091199443e-30,"d":"8.11E-30"},{"v":9.9283327970782e-31,"d":"9.93E-31"},-0.127428609897399,58.6013120584905,"Up"]
[2669,"REACTOME_RHOBTB2_GTPASE_CYCLE",11.5626898381619,0.0954827534571236,{"v":7.35176761156109e-30,"d":"7.35E-30"},{"v":8.9788794716097e-31,"d":"8.98E-31"},-0.189936490651079,58.7008865794252,"Up"]
[2670,"REACTOME_RND3_GTPASE_CYCLE",11.5634812908018,0.0714288873738913,{"v":7.30516040601643e-30,"d":"7.31E-30"},{"v":8.89731075091744e-31,"d":"8.90E-31"},-0.229345675649706,58.7099270476127,"Up"]
[2671,"REACTOME_REGULATION_OF_KIT_SIGNALING",11.582424996187,0.074133862173295,{"v":5.91985109507293e-30,"d":"5.92E-30"},{"v":7.1501575304862e-31,"d":"7.15E-31"},-0.168997522681135,58.9264948414835,"Up"]
[2672,"WP_HEPATITIS_B_INFECTION",11.5832246499604,0.0417719808270226,{"v":5.88185809483417e-30,"d":"5.88E-30"},{"v":7.08442422353508e-31,"d":"7.08E-31"},-0.198973261926234,58.9356442647314,"Up"]
[2673,"KEGG_ETHER_LIPID_METABOLISM",11.5868551258678,0.062790851535224,{"v":5.65612486552963e-30,"d":"5.66E-30"},{"v":6.79345631622317e-31,"d":"6.79E-31"},-0.0587950878494927,58.9771909753833,"Up"]
[2674,"PID_EPHA2_FWD_PATHWAY",11.5989049033227,0.0865831910975007,{"v":4.94850003425395e-30,"d":"4.95E-30"},{"v":5.91015186277293e-31,"d":"5.91E-31"},-0.225253441342513,59.1151785395729,"Up"]
[2675,"REACTOME_EPH_EPHRIN_MEDIATED_REPULSION_OF_CELLS",11.6060272813895,0.0657000527533939,{"v":4.57001806565407e-30,"d":"4.57E-30"},{"v":5.44270032785387e-31,"d":"5.44E-31"},-0.165969291374781,59.1968062485517,"Up"]
[2676,"PID_PDGFRA_PATHWAY",11.6140723198797,0.0838569134732437,{"v":4.17546273249772e-30,"d":"4.18E-30"},{"v":4.95871417624561e-31,"d":"4.96E-31"},-0.21457170116134,59.2890673641422,"Up"]
[2677,"REACTOME_PLATELET_ACTIVATION_SIGNALING_AND_AGGREGATION",11.6154299677602,0.0409998276475355,{"v":4.12203902404885e-30,"d":"4.12E-30"},{"v":4.88136200216311e-31,"d":"4.88E-31"},-0.112980628323518,59.304643149761,"Up"]
[2678,"WP_TGFBETA_SIGNALING_IN_THYROID_CELLS_FOR_EPITHELIALMESENCHYMAL_TRANSITION",11.6373573722134,0.0815814780286162,{"v":3.2060057750662e-30,"d":"3.21E-30"},{"v":3.78576930254106e-31,"d":"3.79E-31"},-0.242944896804409,59.5564550576722,"Up"]
[2679,"REACTOME_ASSOCIATION_OF_TRIC_CCT_WITH_TARGET_PROTEINS_DURING_BIOSYNTHESIS",11.6442656634255,0.0675992437274367,{"v":2.96747855291368e-30,"d":"2.97E-30"},{"v":3.49409586695977e-31,"d":"3.49E-31"},-0.215104380402929,59.6358854830836,"Up"]
[2680,"WP_COMPLEMENT_AND_COAGULATION_CASCADES",11.6471056398585,0.0461161578011372,{"v":2.87947870831981e-30,"d":"2.88E-30"},{"v":3.38076447535524e-31,"d":"3.38E-31"},0.0550320549815394,59.6685524690052,"Up"]
[2681,"WP_GASTRIN_SIGNALING_PATHWAY",11.6619912102755,0.0560050236907753,{"v":2.42913461905305e-30,"d":"2.43E-30"},{"v":2.8438249420088e-31,"d":"2.84E-31"},-0.209925381623083,59.8399021942409,"Up"]
[2682,"WP_PLURIPOTENT_STEM_CELL_DIFFERENTIATION_PATHWAY",11.6655380530146,0.0468409742749102,{"v":2.3377284175536e-30,"d":"2.34E-30"},{"v":2.72892723506594e-31,"d":"2.73E-31"},0.126287827660539,59.8807619815836,"Up"]
[2683,"WP_FOXP3_IN_COVID19",11.67504935532,0.0760553630509064,{"v":2.10501615704978e-30,"d":"2.11E-30"},{"v":2.44306868429529e-31,"d":"2.44E-31"},0.0425536961788847,59.990392681702,"Up"]
[2684,"WP_CHEMOKINE_SIGNALING_PATHWAY",11.7020686303273,0.0363375576930424,{"v":1.54098152603388e-30,"d":"1.54E-30"},{"v":1.78325459996498e-31,"d":"1.78E-31"},-0.103010319637272,60.3023039464846,"Up"]
[2685,"WP_GLYCOLYSIS_AND_GLUCONEOGENESIS",11.7142666017532,0.0787432711025593,{"v":1.34435302567229e-30,"d":"1.34E-30"},{"v":1.54664096408317e-31,"d":"1.55E-31"},-0.128863646018079,60.4433490038771,"Up"]
[2686,"BIOCARTA_IL10_PATHWAY",11.721306082016,0.0909292705931166,{"v":1.24188620188974e-30,"d":"1.24E-30"},{"v":1.42456581863196e-31,"d":"1.42E-31"},-0.117523900941185,60.5248119474116,"Up"]
[2687,"REACTOME_MRNA_SPLICING",11.7329912059044,0.0620602641499813,{"v":1.0865352160454e-30,"d":"1.09E-30"},{"v":1.24269716005192e-31,"d":"1.24E-31"},-0.221028668861546,60.6601414446386,"Up"]
[2688,"REACTOME_SEMA4D_IN_SEMAPHORIN_SIGNALING",11.7589106202389,0.0930930991245183,{"v":8.04541467854048e-31,"d":"8.05E-31"},{"v":9.17459568605494e-32,"d":"9.17E-32"},-0.221196795741933,60.9607944720856,"Up"]
[2689,"KEGG_COLORECTAL_CANCER",11.7600125520008,0.0528348575753101,{"v":7.96574902849527e-31,"d":"7.97E-31"},{"v":9.05687389542141e-32,"d":"9.06E-32"},-0.209085021163857,60.973590757815,"Up"]
[2690,"PID_IL12_STAT4_PATHWAY",11.7715690944149,0.0616342321111805,{"v":6.97695920283751e-31,"d":"6.98E-31"},{"v":7.90910354977531e-32,"d":"7.91E-32"},-0.0528084578838203,61.1078629064947,"Up"]
[2691,"PID_SYNDECAN_1_PATHWAY",11.8481345679941,0.061591715806411,{"v":2.84214401943218e-31,"d":"2.84E-31"},{"v":3.21227478579548e-32,"d":"3.21E-32"},-0.104220574401098,62.0007163048192,"Up"]
[2692,"REACTOME_ADAPTIVE_IMMUNE_SYSTEM",11.8505071352592,0.03807727830007,{"v":2.77191226304509e-31,"d":"2.77E-31"},{"v":3.12354485781734e-32,"d":"3.12E-32"},-0.139022443791441,62.028474045018,"Up"]
[2693,"REACTOME_SLC_MEDIATED_TRANSMEMBRANE_TRANSPORT",11.8516632381136,0.0272122383598911,{"v":2.74254105456836e-31,"d":"2.74E-31"},{"v":3.0811949094847e-32,"d":"3.08E-32"},0.0303361792786635,62.0420017876899,"Up"]
[2694,"WP_VEGFAVEGFR2_SIGNALING_PATHWAY",11.8617627234362,0.0541773168056992,{"v":2.4414323324775e-31,"d":"2.44E-31"},{"v":2.73466779481285e-32,"d":"2.73E-32"},-0.168026644254329,62.1602323912983,"Up"]
[2695,"REACTOME_GLUCONEOGENESIS",11.8655878348814,0.0807153272913793,{"v":2.34055707053291e-31,"d":"2.34E-31"},{"v":2.61377999442103e-32,"d":"2.61E-32"},-0.121168006132962,62.2050371640298,"Up"]
[2696,"REACTOME_METABOLISM_OF_WATER_SOLUBLE_VITAMINS_AND_COFACTORS",11.8682093906046,0.0309110504570117,{"v":2.27600105334091e-31,"d":"2.28E-31"},{"v":2.53400926991396e-32,"d":"2.53E-32"},-0.0907692408276756,62.2357524630853,"Up"]
[2697,"REACTOME_INTERLEUKIN_12_FAMILY_SIGNALING",11.8699352040192,0.0824770603371889,{"v":2.23680151082741e-31,"d":"2.24E-31"},{"v":2.48281949076321e-32,"d":"2.48E-32"},-0.160531695475322,62.2559764764759,"Up"]
[2698,"REACTOME_NUCLEAR_SIGNALING_BY_ERBB4",11.8713882354625,0.0649626562707922,{"v":2.20539496016539e-31,"d":"2.21E-31"},{"v":2.44051803958923e-32,"d":"2.44E-32"},-0.16518029424281,62.2730061150475,"Up"]
[2699,"BIOCARTA_AGR_PATHWAY",11.871893273514,0.0707058633299356,{"v":2.19896473080004e-31,"d":"2.20E-31"},{"v":2.4259833568543e-32,"d":"2.43E-32"},-0.159339539864063,62.2789256770371,"Up"]
[2700,"REACTOME_EPHRIN_SIGNALING",11.872506275262,0.0791318423627504,{"v":2.18977501487133e-31,"d":"2.19E-31"},{"v":2.40845700016212e-32,"d":"2.41E-32"},-0.196510235759402,62.2861110149817,"Up"]
[2701,"BIOCARTA_BAD_PATHWAY",11.8751539592821,0.0734547645139225,{"v":2.12878147208026e-31,"d":"2.13E-31"},{"v":2.33419021061432e-32,"d":"2.33E-32"},-0.177142186033031,62.3171501781604,"Up"]
[2702,"REACTOME_MELANIN_BIOSYNTHESIS",11.8855586884192,0.106596122780843,{"v":1.8879308746284e-31,"d":"1.89E-31"},{"v":2.0637301058691e-32,"d":"2.06E-32"},0.135196827866275,62.4391918567452,"Up"]
[2703,"WP_PHYSICOCHEMICAL_FEATURES_AND_TOXICITYASSOCIATED_PATHWAYS",11.8927134908057,0.0572243750855478,{"v":1.73990115734556e-31,"d":"1.74E-31"},{"v":1.89604613300478e-32,"d":"1.90E-32"},-0.168254092555344,62.5231743987363,"Up"]
[2704,"REACTOME_INTERLEUKIN_1_PROCESSING",11.9024379342354,0.0962299924449458,{"v":1.55530238612471e-31,"d":"1.56E-31"},{"v":1.68963349639729e-32,"d":"1.69E-32"},-0.228995683069494,62.637398490387,"Up"]
[2705,"REACTOME_A_TETRASACCHARIDE_LINKER_SEQUENCE_IS_REQUIRED_FOR_GAG_SYNTHESIS",11.9091989708429,0.0729884884802083,{"v":1.43992576351709e-31,"d":"1.44E-31"},{"v":1.55943377223004e-32,"d":"1.56E-32"},-0.105712630125181,62.7168680090192,"Up"]
[2706,"WP_ENDOCHONDRAL_OSSIFICATION",11.9123164039227,0.0476187414068059,{"v":1.39197383541947e-31,"d":"1.39E-31"},{"v":1.50280576023694e-32,"d":"1.50E-32"},-0.109269053560073,62.7535253285743,"Up"]
[2707,"WP_ENDOCHONDRAL_OSSIFICATION_WITH_SKELETAL_DYSPLASIAS",11.9123164039227,0.0476187414068059,{"v":1.39197383541947e-31,"d":"1.39E-31"},{"v":1.50280576023694e-32,"d":"1.50E-32"},-0.109269053560073,62.7535253285743,"Up"]
[2708,"PID_HIF2PATHWAY",11.9164743842205,0.0704330359189751,{"v":1.33328074706029e-31,"d":"1.33E-31"},{"v":1.43044290676508e-32,"d":"1.43E-32"},-0.181946118619727,62.8024328626572,"Up"]
[2709,"KEGG_SYSTEMIC_LUPUS_ERYTHEMATOSUS",11.9221528240242,0.0440677144699528,{"v":1.25028284078345e-31,"d":"1.25E-31"},{"v":1.33717834186354e-32,"d":"1.34E-32"},0.165062011207491,62.8692515214334,"Up"]
[2710,"BIOCARTA_UCALPAIN_PATHWAY",11.9267199441589,0.109949913591911,{"v":1.188009931308e-31,"d":"1.19E-31"},{"v":1.26656929248761e-32,"d":"1.27E-32"},-0.151997153721489,62.9230157931183,"Up"]
[2711,"BIOCARTA_IFNG_PATHWAY",11.9441773399685,0.144458635230052,{"v":9.68409342679656e-32,"d":"9.68E-32"},{"v":1.029179969447e-32,"d":"1.03E-32"},-0.267980309563277,63.128710467477,"Up"]
[2712,"PID_IL4_2PATHWAY",11.9534174889448,0.0494082045116747,{"v":8.70319679359703e-32,"d":"8.70E-32"},{"v":9.21998580698201e-33,"d":"9.22E-33"},-0.135149775738805,63.2377032009729,"Up"]
[2713,"WP_MOLYBDENUM_COFACTOR_MOCO_BIOSYNTHESIS",11.9580655570339,0.0845795591823061,{"v":8.26086282301077e-32,"d":"8.26E-32"},{"v":8.72351573415105e-33,"d":"8.72E-33"},0.140548632291861,63.2925609422742,"Up"]
[2714,"REACTOME_INTERLEUKIN_23_SIGNALING",11.9795902738642,0.113610289847808,{"v":6.41175419212868e-32,"d":"6.41E-32"},{"v":6.74921493908282e-33,"d":"6.75E-33"},0.0117357721621024,63.5468734436718,"Up"]
[2715,"REACTOME_SIGNALING_BY_RECEPTOR_TYROSINE_KINASES",11.980094522009,0.0416789591659926,{"v":6.39378672438962e-32,"d":"6.39E-32"},{"v":6.70873033497021e-33,"d":"6.71E-33"},-0.155001992463498,63.5528364517342,"Up"]
[2716,"REACTOME_EXTRINSIC_PATHWAY_OF_FIBRIN_CLOT_FORMATION",11.9804039421409,0.0821255128916581,{"v":6.39077353883031e-32,"d":"6.39E-32"},{"v":6.68400741240687e-33,"d":"6.68E-33"},0.203945902471279,63.5564956343385,"Up"]
[2717,"KEGG_ERBB_SIGNALING_PATHWAY",11.980871866796,0.0494603648349354,{"v":6.375757425142469e-32,"d":"6.38E-32"},{"v":6.64679164766877e-33,"d":"6.65E-33"},-0.213761718520558,63.5620294568838,"Up"]
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[2719,"PID_ALK2_PATHWAY",11.9982647276164,0.100576688669175,{"v":5.21380268858261e-32,"d":"5.21E-32"},{"v":5.40026121928091e-33,"d":"5.40E-33"},-0.139695294950492,63.7678728318338,"Up"]
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[2743,"REACTOME_GLUCAGON_SIGNALING_IN_METABOLIC_REGULATION",12.3155089581346,0.0737250705976679,{"v":1.23855633700414e-33,"d":"1.24E-33"},{"v":1.16166889907946e-34,"d":"1.16E-34"},-0.0480103168583416,67.573664344593,"Up"]
[2744,"PID_INTEGRIN_A4B1_PATHWAY",12.3231625473109,0.0765957486196901,{"v":1.13171652641853e-33,"d":"1.13E-33"},{"v":1.05764331247615e-34,"d":"1.06E-34"},-0.169439610257838,67.6666790575126,"Up"]
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[2762,"PID_INTEGRIN_CS_PATHWAY",12.6714273749075,0.0910043193884043,{"v":1.60885906567179e-35,"d":"1.61E-35"},{"v":1.39499588352783e-36,"d":"1.39E-36"},-0.0670590163888168,71.9588694691268,"Up"]
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[2778,"WP_ARRHYTHMOGENIC_RIGHT_VENTRICULAR_CARDIOMYOPATHY",12.9548316462825,0.0651467218542823,{"v":4.7491710192091e-37,"d":"4.75E-37"},{"v":3.7813912298696e-38,"d":"3.78E-38"},-0.0126521094833321,75.5377989895319,"Up"]
[2779,"PID_LYSOPHOSPHOLIPID_PATHWAY",12.9701905650873,0.0613107250658814,{"v":3.91372262029713e-37,"d":"3.91E-37"},{"v":3.10298520840022e-38,"d":"3.10E-38"},-0.155679880300481,75.7339613881495,"Up"]
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[2783,"WP_PANCREATIC_ADENOCARCINOMA_PATHWAY",13.0652297279111,0.0592112034294168,{"v":1.16547195931989e-37,"d":"1.17E-37"},{"v":9.08313166676429e-39,"d":"9.08E-39"},-0.212549487514456,76.9528278001472,"Up"]
[2784,"WP_LINOLEIC_ACID_METABOLISM_AFFECTED_BY_CORONAVIRUS_INFECTION",13.070316647879,0.076954694922322,{"v":1.10056300923496e-37,"d":"1.10E-37"},{"v":8.50300030751709e-39,"d":"8.50E-39"},0.195487880501716,77.0183114207684,"Up"]
[2785,"REACTOME_MET_INTERACTS_WITH_TNS_PROTEINS",13.0889166750963,0.157575220446993,{"v":8.68196391017421e-38,"d":"8.68E-38"},{"v":6.67843377705709e-39,"d":"6.68E-39"},-0.198282542294225,77.2579598777404,"Up"]
[2786,"BIOCARTA_TH1TH2_PATHWAY",13.1168570507446,0.0908077174381473,{"v":6.06293924376326e-38,"d":"6.06E-38"},{"v":4.64334415767294e-39,"d":"4.64E-39"},-0.0205749980039667,77.6185761397358,"Up"]
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[2924,"REACTOME_BUTYROPHILIN_BTN_FAMILY_INTERACTIONS",11.82431944,0.172581505,{"v":1.68e-29,"d":"1.68E-29"},{"v":3.46e-31,"d":"3.46E-31"},0.08226832,59.90390524,"Up"]
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[2922,"REACTOME_CYTOCHROME_P450_ARRANGED_BY_SUBSTRATE_TYPE",11.77179758,0.09423317,{"v":2.87e-29,"d":"2.87E-29"},{"v":6.19e-31,"d":"6.19E-31"},0.038667058,59.32892052,"Up"]
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[2920,"WP_GENES_ASSOCIATED_WITH_THE_DEVELOPMENT_OF_RHEUMATOID_ARTHRITIS",11.63156632,0.156292629,{"v":1.28e-28,"d":"1.28E-28"},{"v":2.9e-30,"d":"2.90E-30"},0.019336421,57.80458731,"Up"]
[2919,"WP_EICOSANOID_METABOLISM_VIA_CYCLOOXYGENASES_COX",11.58787908,0.124772217,{"v":2.04e-28,"d":"2.04E-28"},{"v":4.67e-30,"d":"4.67E-30"},-0.069439543,57.33293621,"Up"]
[2918,"WP_GLIAL_CELL_DIFFERENTIATION",11.55046371,0.212033829,{"v":2.97e-28,"d":"2.97E-28"},{"v":7.01e-30,"d":"7.01E-30"},-0.180616492,56.93022193,"Up"]
[2917,"REACTOME_BILE_ACID_AND_BILE_SALT_METABOLISM",11.52721189,0.10526241,{"v":3.78e-28,"d":"3.78E-28"},{"v":9.03e-30,"d":"9.03E-30"},-0.132850304,56.68052487,"Up"]
[2916,"REACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS",11.40673001,0.107718409,{"v":1.35e-27,"d":"1.35E-27"},{"v":3.32e-29,"d":"3.32E-29"},-0.152508886,55.39370742,"Up"]
[2915,"REACTOME_NF_KB_ACTIVATION_THROUGH_FADD_RIP_1_PATHWAY_MEDIATED_BY_CASPASE_8_AND_10",11.37670205,0.149811194,{"v":1.82e-27,"d":"1.82E-27"},{"v":4.59e-29,"d":"4.59E-29"},-0.139411264,55.07482582,"Up"]
[2914,"REACTOME_CHEMOKINE_RECEPTORS_BIND_CHEMOKINES",11.34658193,0.075933692,{"v":2.48e-27,"d":"2.48E-27"},{"v":6.34e-29,"d":"6.34E-29"},0.325189,54.75570243,"Up"]
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[2911,"NABA_COLLAGENS",11.19746999,0.188169989,{"v":1.15e-26,"d":"1.15E-26"},{"v":3.1e-28,"d":"3.10E-28"},-0.14787829,53.18675665,"Up"]
[2912,"REACTOME_COLLAGEN_CHAIN_TRIMERIZATION",11.19746999,0.188169989,{"v":1.15e-26,"d":"1.15E-26"},{"v":3.1e-28,"d":"3.10E-28"},-0.14787829,53.18675665,"Up"]
[2910,"REACTOME_LTC4_CYSLTR_MEDIATED_IL4_PRODUCTION",11.18910273,0.187645154,{"v":1.24e-26,"d":"1.24E-26"},{"v":3.39e-28,"d":"3.39E-28"},0.170286476,53.09925547,"Up"]
[2909,"KEGG_COMPLEMENT_AND_COAGULATION_CASCADES",11.18618408,0.111956821,{"v":1.27e-26,"d":"1.27E-26"},{"v":3.5e-28,"d":"3.50E-28"},0.064456862,53.06874692,"Up"]
[2908,"REACTOME_SIGNALING_BY_LRP5_MUTANTS",11.13247821,0.237846325,{"v":2.18e-26,"d":"2.18E-26"},{"v":6.16e-28,"d":"6.16E-28"},-0.021941003,52.50860822,"Up"]
[2907,"REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS",11.11000013,0.05719812,{"v":2.73e-26,"d":"2.73E-26"},{"v":7.81e-28,"d":"7.81E-28"},0.270145766,52.2748698,"Up"]
[2906,"REACTOME_DEFECTIVE_FACTOR_VIII_CAUSES_HEMOPHILIA_A",11.0542341,0.2307869,{"v":4.78e-26,"d":"4.78E-26"},{"v":1.4e-27,"d":"1.40E-27"},-0.007487114,51.69677888,"Up"]
[2905,"KEGG_CYTOKINE_CYTOKINE_RECEPTOR_INTERACTION",11.05299036,0.055192649,{"v":4.79e-26,"d":"4.79E-26"},{"v":1.42e-27,"d":"1.42E-27"},0.109994434,51.683915,"Up"]
[2904,"REACTOME_NEUROFASCIN_INTERACTIONS",11.04743571,0.222027435,{"v":5.02e-26,"d":"5.02E-26"},{"v":1.51e-27,"d":"1.51E-27"},0.038769431,51.62647913,"Up"]
[2903,"REACTOME_SYNTHESIS_OF_16_20_HYDROXYEICOSATETRAENOIC_ACIDS_HETE",11.03912054,0.217545765,{"v":5.42e-26,"d":"5.42E-26"},{"v":1.64e-27,"d":"1.64E-27"},0.038448336,51.54054676,"Up"]
[2902,"REACTOME_PEROXISOMAL_LIPID_METABOLISM",10.99166984,0.129036238,{"v":8.8e-26,"d":"8.80E-26"},{"v":2.7e-27,"d":"2.70E-27"},-0.053336022,51.0512608,"Up"]
[2901,"REACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS_VIA_27_HYDROXYCHOLESTEROL",10.96026798,0.142830766,{"v":1.21e-25,"d":"1.21E-25"},{"v":3.74e-27,"d":"3.74E-27"},-0.182248524,50.72848251,"Up"]
[2900,"NABA_MATRISOME_ASSOCIATED",10.91056722,0.035018171,{"v":2e-25,"d":"2.00E-25"},{"v":6.26e-27,"d":"6.26E-27"},0.018448628,50.21927454,"Up"]
[2899,"REACTOME_METABOLISM_OF_INGESTED_SEMET_SEC_MESEC_INTO_H2SE",10.88631414,0.144062963,{"v":2.54e-25,"d":"2.54E-25"},{"v":8.05e-27,"d":"8.05E-27"},0.061153633,49.97153149,"Up"]
[2898,"WP_GDNFRET_SIGNALING_AXIS",10.84714419,0.119406748,{"v":3.77e-25,"d":"3.77E-25"},{"v":1.21e-26,"d":"1.21E-26"},-0.149964214,49.57244188,"Up"]
[2897,"REACTOME_HDL_REMODELING",10.8052003,0.184770309,{"v":5.74e-25,"d":"5.74E-25"},{"v":1.86e-26,"d":"1.86E-26"},-0.093579019,49.14649912,"Up"]
[2896,"REACTOME_ENDOGENOUS_STEROLS",10.77500776,0.110459774,{"v":7.74e-25,"d":"7.74E-25"},{"v":2.53e-26,"d":"2.53E-26"},-0.141387568,48.84079547,"Up"]
[2895,"REACTOME_DISEASES_OF_GLYCOSYLATION",10.75457496,0.062498008,{"v":9.45e-25,"d":"9.45E-25"},{"v":3.12e-26,"d":"3.12E-26"},-0.130696091,48.63434008,"Up"]
[2894,"REACTOME_PHASE_I_FUNCTIONALIZATION_OF_COMPOUNDS",10.75297472,0.06940214,{"v":9.51e-25,"d":"9.51E-25"},{"v":3.17e-26,"d":"3.17E-26"},-0.010633959,48.61818567,"Up"]
[2893,"KEGG_GLYCOSYLPHOSPHATIDYLINOSITOL_GPI_ANCHOR_BIOSYNTHESIS",10.68065216,0.110033682,{"v":1.95e-24,"d":"1.95E-24"},{"v":6.63e-26,"d":"6.63E-26"},-0.141254121,47.8903159,"Up"]
[2892,"WP_COMPLEMENT_AND_COAGULATION_CASCADES",10.64835961,0.103687884,{"v":2.68e-24,"d":"2.68E-24"},{"v":9.2e-26,"d":"9.20E-26"},0.014359085,47.56672345,"Up"]
[2891,"REACTOME_ACTIVATION_OF_C3_AND_C5",10.64515335,0.217593073,{"v":2.74e-24,"d":"2.74E-24"},{"v":9.5e-26,"d":"9.50E-26"},0.127445062,47.53464208,"Up"]
[2890,"KEGG_ABC_TRANSPORTERS",10.58274979,0.097923819,{"v":5.05e-24,"d":"5.05E-24"},{"v":1.79e-25,"d":"1.79E-25"},0.069009364,46.91195006,"Up"]
[2889,"REACTOME_RESOLUTION_OF_D_LOOP_STRUCTURES_THROUGH_SYNTHESIS_DEPENDENT_STRAND_ANNEALING_SDSA",10.5605965,0.093911965,{"v":6.25e-24,"d":"6.25E-24"},{"v":2.23e-25,"d":"2.23E-25"},0.032210467,46.69167673,"Up"]
[2888,"REACTOME_NEGATIVE_REGULATION_OF_TCF_DEPENDENT_SIGNALING_BY_WNT_LIGAND_ANTAGONISTS",10.54050584,0.128714717,{"v":7.58e-24,"d":"7.58E-24"},{"v":2.73e-25,"d":"2.73E-25"},-0.0046194,46.49226727,"Up"]
[2887,"BIOCARTA_MSP_PATHWAY",10.53931361,0.182751946,{"v":7.6e-24,"d":"7.60E-24"},{"v":2.76e-25,"d":"2.76E-25"},-0.044502642,46.48044445,"Up"]
[2886,"REACTOME_SYNTHESIS_OF_GLYCOSYLPHOSPHATIDYLINOSITOL_GPI",10.45304828,0.126782718,{"v":1.79e-23,"d":"1.79E-23"},{"v":6.56e-25,"d":"6.56E-25"},-0.150620929,45.62814877,"Up"]
[2885,"REACTOME_POTASSIUM_CHANNELS",10.43563286,0.057376286,{"v":2.11e-23,"d":"2.11E-23"},{"v":7.8e-25,"d":"7.80E-25"},0.228514966,45.45684293,"Up"]
[2884,"WP_GPCRS_CLASS_B_SECRETINLIKE",10.41611164,0.118312978,{"v":2.5e-23,"d":"2.50E-23"},{"v":9.48e-25,"d":"9.48E-25"},0.040905783,45.26512625,"Up"]
[2883,"WP_TYPE_I_INTERFERON_INDUCTION_AND_SIGNALING_DURING_SARSCOV2_INFECTION",10.41566418,0.107175531,{"v":2.5e-23,"d":"2.50E-23"},{"v":9.52e-25,"d":"9.52E-25"},-0.122047507,45.26073558,"Up"]
[2882,"WP_MED_AND_PSEUDOACHONDROPLASIA_GENES",10.3756721,0.090399467,{"v":3.69e-23,"d":"3.69E-23"},{"v":1.42e-24,"d":"1.42E-24"},0.411450672,44.86899126,"Up"]
[2881,"REACTOME_TP53_REGULATES_TRANSCRIPTION_OF_CASPASE_ACTIVATORS_AND_CASPASES",10.31920762,0.140692399,{"v":6.28e-23,"d":"6.28E-23"},{"v":2.47e-24,"d":"2.47E-24"},-0.041159108,44.31818297,"Up"]
[2880,"SA_CASPASE_CASCADE",10.293509,0.121504508,{"v":8.02e-23,"d":"8.02E-23"},{"v":3.19e-24,"d":"3.19E-24"},-0.127622288,44.06838395,"Up"]
[2879,"REACTOME_RESOLUTION_OF_D_LOOP_STRUCTURES",10.27813473,0.088329145,{"v":9.25e-23,"d":"9.25E-23"},{"v":3.71e-24,"d":"3.71E-24"},0.080957426,43.91920734,"Up"]
[2878,"WP_TRIACYLGLYCERIDE_SYNTHESIS",10.27026313,0.113366848,{"v":9.91e-23,"d":"9.91E-23"},{"v":4.01e-24,"d":"4.01E-24"},-0.13048991,43.84290642,"Up"]
[2877,"REACTOME_ALPHA_OXIDATION_OF_PHYTANATE",10.25274259,0.177201174,{"v":1.17e-22,"d":"1.17E-22"},{"v":4.76e-24,"d":"4.76E-24"},0.022869781,43.67326426,"Up"]
[2876,"REACTOME_THE_ACTIVATION_OF_ARYLSULFATASES",10.24715545,0.156967465,{"v":1.22e-22,"d":"1.22E-22"},{"v":5.03e-24,"d":"5.03E-24"},-0.081042749,43.61922155,"Up"]
[2875,"REACTOME_CLASS_A_1_RHODOPSIN_LIKE_RECEPTORS",10.21619341,0.049454307,{"v":1.64e-22,"d":"1.64E-22"},{"v":6.81e-24,"d":"6.81E-24"},0.313144936,43.32021287,"Up"]
[2874,"WP_NICOTINE_METABOLISM_IN_LIVER_CELLS",10.18529444,0.188737359,{"v":2.2e-22,"d":"2.20E-22"},{"v":9.2e-24,"d":"9.20E-24"},0.008147569,43.02262176,"Up"]
[2873,"REACTOME_CA2_ACTIVATED_K_CHANNELS",10.07977143,0.085727551,{"v":5.99e-22,"d":"5.99E-22"},{"v":2.56e-23,"d":"2.56E-23"},0.355746084,42.01241797,"Up"]
[2872,"WP_SEROTONIN_AND_ANXIETY",10.06256151,0.142752193,{"v":7.02e-22,"d":"7.02E-22"},{"v":3.03e-23,"d":"3.03E-23"},-0.018630025,41.84855848,"Up"]
[2871,"REACTOME_ABC_TRANSPORTERS_IN_LIPID_HOMEOSTASIS",10.02165142,0.113267704,{"v":1.03e-21,"d":"1.03E-21"},{"v":4.49e-23,"d":"4.49E-23"},0.053842515,41.46005508,"Up"]
[2870,"REACTOME_HOMOLOGOUS_DNA_PAIRING_AND_STRAND_EXCHANGE",10.0077895,0.077600867,{"v":1.17e-21,"d":"1.17E-21"},{"v":5.13e-23,"d":"5.13E-23"},-0.036092512,41.32873811,"Up"]
[2869,"REACTOME_DISEASES_ASSOCIATED_WITH_O_GLYCOSYLATION_OF_PROTEINS",9.994156409,0.074174856,{"v":1.32e-21,"d":"1.32E-21"},{"v":5.85e-23,"d":"5.85E-23"},-0.031713102,41.19974846,"Up"]
[2868,"BIOCARTA_COMP_PATHWAY",9.980766904,0.155182448,{"v":1.49e-21,"d":"1.49E-21"},{"v":6.65e-23,"d":"6.65E-23"},0.133478422,41.07321759,"Up"]
[2867,"KEGG_INTESTINAL_IMMUNE_NETWORK_FOR_IGA_PRODUCTION",9.956785118,0.091070525,{"v":1.85e-21,"d":"1.85E-21"},{"v":8.36e-23,"d":"8.36E-23"},0.043151,40.8469715,"Up"]
[2866,"REACTOME_CHYLOMICRON_CLEARANCE",9.919270303,0.159153806,{"v":2.63e-21,"d":"2.63E-21"},{"v":1.2e-22,"d":"1.20E-22"},-0.008061828,40.49403753,"Up"]
[2865,"REACTOME_DISEASES_OF_DNA_REPAIR",9.916613044,0.079963846,{"v":2.68e-21,"d":"2.68E-21"},{"v":1.23e-22,"d":"1.23E-22"},-0.030720005,40.46908398,"Up"]
[2864,"REACTOME_DEFECTS_IN_COBALAMIN_B12_METABOLISM",9.896899048,0.126221012,{"v":3.21e-21,"d":"3.21E-21"},{"v":1.48e-22,"d":"1.48E-22"},-0.106081491,40.28414379,"Up"]
[2863,"REACTOME_TRNA_MODIFICATION_IN_THE_NUCLEUS_AND_CYTOSOL",9.881678309,0.08320952,{"v":3.68e-21,"d":"3.68E-21"},{"v":1.71e-22,"d":"1.71E-22"},-0.154097554,40.1415827,"Up"]
[2862,"WP_RIBOFLAVIN_AND_COQ_DISORDERS",9.865147832,0.115372261,{"v":4.27e-21,"d":"4.27E-21"},{"v":2e-22,"d":"2.00E-22"},-0.144812938,39.9869786,"Up"]
[2861,"REACTOME_KERATAN_SULFATE_BIOSYNTHESIS",9.850727121,0.095816912,{"v":4.86e-21,"d":"4.86E-21"},{"v":2.29e-22,"d":"2.29E-22"},-0.096683352,39.85229729,"Up"]
[2860,"REACTOME_LEUKOTRIENE_RECEPTORS",9.846666647,0.092504237,{"v":5.02e-21,"d":"5.02E-21"},{"v":2.38e-22,"d":"2.38E-22"},0.300968505,39.81440685,"Up"]
[2859,"BIOCARTA_CASPASE_PATHWAY",9.837954339,0.108305515,{"v":5.41e-21,"d":"5.41E-21"},{"v":2.59e-22,"d":"2.59E-22"},-0.093560428,39.73315528,"Up"]
[2858,"WP_FOXP3_IN_COVID19",9.831813342,0.10820924,{"v":5.7e-21,"d":"5.70E-21"},{"v":2.74e-22,"d":"2.74E-22"},0.171363427,39.67592296,"Up"]
[2857,"KEGG_TAURINE_AND_HYPOTAURINE_METABOLISM",9.816703793,0.119600106,{"v":6.52e-21,"d":"6.52E-21"},{"v":3.16e-22,"d":"3.16E-22"},0.069753585,39.53524378,"Up"]
[2856,"REACTOME_DISEASES_ASSOCIATED_WITH_SURFACTANT_METABOLISM",9.814150657,0.06288038,{"v":6.64e-21,"d":"6.64E-21"},{"v":3.24e-22,"d":"3.24E-22"},0.337947082,39.51149182,"Up"]
[2855,"REACTOME_SLC_MEDIATED_TRANSMEMBRANE_TRANSPORT",9.805352165,0.04601288,{"v":7.16e-21,"d":"7.16E-21"},{"v":3.52e-22,"d":"3.52E-22"},0.016589904,39.42968177,"Up"]
[2854,"REACTOME_INTERLEUKIN_10_SIGNALING",9.785401413,0.066455095,{"v":8.58e-21,"d":"8.58E-21"},{"v":4.25e-22,"d":"4.25E-22"},0.15968712,39.2444216,"Up"]
[2853,"WP_COVID19_THROMBOSIS_AND_ANTICOAGULATION",9.745351949,0.40153437,{"v":1.24e-20,"d":"1.24E-20"},{"v":6.19e-22,"d":"6.19E-22"},0.199848441,38.8735575,"Up"]
[2852,"BIOCARTA_AMI_PATHWAY",9.732845429,0.144029603,{"v":1.39e-20,"d":"1.39E-20"},{"v":6.96e-22,"d":"6.96E-22"},0.016387273,38.75802722,"Up"]
[2851,"REACTOME_PHOSPHATE_BOND_HYDROLYSIS_BY_NTPDASE_PROTEINS",9.728100393,0.136448719,{"v":1.44e-20,"d":"1.44E-20"},{"v":7.28e-22,"d":"7.28E-22"},0.079008255,38.7142296,"Up"]
[2850,"REACTOME_TLR3_MEDIATED_TICAM1_DEPENDENT_PROGRAMMED_CELL_DEATH",9.725396401,0.132930975,{"v":1.47e-20,"d":"1.47E-20"},{"v":7.47e-22,"d":"7.47E-22"},-0.047103444,38.68927987,"Up"]
[2849,"WP_GPCRS_CLASS_A_RHODOPSINLIKE",9.694443413,0.055991748,{"v":1.93e-20,"d":"1.93E-20"},{"v":9.97e-22,"d":"9.97E-22"},0.339970197,38.40412413,"Up"]
[2848,"REACTOME_SODIUM_PROTON_EXCHANGERS",9.677614709,0.132351868,{"v":2.25e-20,"d":"2.25E-20"},{"v":1.17e-21,"d":"1.17E-21"},0.007963038,38.24943452,"Up"]
[2847,"REACTOME_DEFECTS_IN_VITAMIN_AND_COFACTOR_METABOLISM",9.639293304,0.104984935,{"v":3.19e-20,"d":"3.19E-20"},{"v":1.67e-21,"d":"1.67E-21"},-0.110475719,37.89809282,"Up"]
[2846,"REACTOME_BIOLOGICAL_OXIDATIONS",9.636596411,0.045941386,{"v":3.25e-20,"d":"3.25E-20"},{"v":1.71e-21,"d":"1.71E-21"},-0.035492796,37.87341454,"Up"]
[2845,"WP_SEROTONIN_AND_ANXIETYRELATED_EVENTS",9.634096229,0.151157504,{"v":3.31e-20,"d":"3.31E-20"},{"v":1.75e-21,"d":"1.75E-21"},0.049775295,37.85054188,"Up"]
[2844,"REACTOME_NCAM1_INTERACTIONS",9.626103969,0.139660661,{"v":3.54e-20,"d":"3.54E-20"},{"v":1.88e-21,"d":"1.88E-21"},-0.078641242,37.77746161,"Up"]
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[2842,"REACTOME_COLLAGEN_BIOSYNTHESIS_AND_MODIFYING_ENZYMES",9.561477416,0.144755073,{"v":6.36e-20,"d":"6.36E-20"},{"v":3.42e-21,"d":"3.42E-21"},-0.174304305,37.18854655,"Up"]
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[2793,"REACTOME_COLLAGEN_FORMATION",8.212146963,0.109825795,{"v":4.93e-15,"d":"4.93E-15"},{"v":3.95e-16,"d":"3.95E-16"},-0.171433752,25.72616696,"Up"]
[2792,"REACTOME_DISEASES_ASSOCIATED_WITH_N_GLYCOSYLATION_OF_PROTEINS",8.171349253,0.089452634,{"v":6.81e-15,"d":"6.81E-15"},{"v":5.48e-16,"d":"5.48E-16"},-0.169974339,25.40470783,"Up"]
[2791,"WP_PROSTAGLANDIN_SYNTHESIS_AND_REGULATION",8.165922394,0.078939514,{"v":7.07e-15,"d":"7.07E-15"},{"v":5.73e-16,"d":"5.73E-16"},-0.100589545,25.36206021,"Up"]
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[2789,"REACTOME_ROBO_RECEPTORS_BIND_AKAP5",8.146372271,0.11690819,{"v":8.21e-15,"d":"8.21E-15"},{"v":6.69e-16,"d":"6.69E-16"},-0.228300507,25.20864221,"Up"]
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[2786,"BIOCARTA_EXTRINSIC_PATHWAY",8.105537498,0.121208647,{"v":1.11e-14,"d":"1.11E-14"},{"v":9.27e-16,"d":"9.27E-16"},0.024806509,24.88930126,"Up"]
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[2784,"REACTOME_REGULATION_BY_C_FLIP",8.083904023,0.110449074,{"v":1.31e-14,"d":"1.31E-14"},{"v":1.1e-15,"d":"1.10E-15"},-0.10463912,24.72072748,"Up"]
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[2782,"BIOCARTA_TCAPOPTOSIS_PATHWAY",8.0647756,0.058357152,{"v":1.52e-14,"d":"1.52E-14"},{"v":1.28e-15,"d":"1.28E-15"},0.489833065,24.57202412,"Up"]
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[2780,"WP_PEPTIDE_GPCRS",8.035444987,0.062757599,{"v":1.88e-14,"d":"1.88E-14"},{"v":1.62e-15,"d":"1.62E-15"},0.36594291,24.3446486,"Up"]
[2779,"REACTOME_CLASS_I_PEROXISOMAL_MEMBRANE_PROTEIN_IMPORT",8.027810848,0.085044631,{"v":1.99e-14,"d":"1.99E-14"},{"v":1.72e-15,"d":"1.72E-15"},-0.172113528,24.2855945,"Up"]
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[2777,"WP_GENES_CONTROLLING_NEPHROGENESIS",7.997047727,0.072351043,{"v":2.51e-14,"d":"2.51E-14"},{"v":2.19e-15,"d":"2.19E-15"},-0.121098524,24.04815722,"Up"]
[2776,"REACTOME_HDR_THROUGH_SINGLE_STRAND_ANNEALING_SSA",7.984167148,0.058850668,{"v":2.77e-14,"d":"2.77E-14"},{"v":2.42e-15,"d":"2.42E-15"},-0.109110139,23.94899491,"Up"]
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[2774,"WP_SARS_CORONAVIRUS_AND_INNATE_IMMUNITY",7.968689922,0.09305753,{"v":3.1e-14,"d":"3.10E-14"},{"v":2.73e-15,"d":"2.73E-15"},-0.144074615,23.83003981,"Up"]
[2773,"WP_JOUBERT_SYNDROME",7.967755599,0.049304491,{"v":3.12e-14,"d":"3.12E-14"},{"v":2.75e-15,"d":"2.75E-15"},-0.128743408,23.82286569,"Up"]
[2772,"REACTOME_METABOLISM_OF_AMINE_DERIVED_HORMONES",7.927150768,0.067530458,{"v":4.25e-14,"d":"4.25E-14"},{"v":3.78e-15,"d":"3.78E-15"},0.375060534,23.51184527,"Up"]
[2771,"REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS",7.901856537,0.089818799,{"v":5.15e-14,"d":"5.15E-14"},{"v":4.6e-15,"d":"4.60E-15"},0.045913492,23.31885123,"Up"]
[2770,"WP_NEPHROGENESIS",7.893713079,0.094510912,{"v":5.47e-14,"d":"5.47E-14"},{"v":4.9e-15,"d":"4.90E-15"},-0.070181292,23.25683986,"Up"]
[2769,"REACTOME_LYSINE_CATABOLISM",7.884904828,0.084754198,{"v":5.81e-14,"d":"5.81E-14"},{"v":5.24e-15,"d":"5.24E-15"},-0.138171729,23.1898336,"Up"]
[2768,"REACTOME_CELLULAR_HEXOSE_TRANSPORT",7.88141791,0.074858533,{"v":5.95e-14,"d":"5.95E-14"},{"v":5.39e-15,"d":"5.39E-15"},0.223774632,23.16332723,"Up"]
[2767,"REACTOME_SCAVENGING_BY_CLASS_B_RECEPTORS",7.875597674,0.085454742,{"v":6.2e-14,"d":"6.20E-14"},{"v":5.64e-15,"d":"5.64E-15"},0.274464794,23.11910823,"Up"]
[2766,"REACTOME_BRANCHED_CHAIN_AMINO_ACID_CATABOLISM",7.873861937,0.078503929,{"v":6.26e-14,"d":"6.26E-14"},{"v":5.71e-15,"d":"5.71E-15"},-0.207148916,23.10592697,"Up"]
[2765,"NABA_ECM_AFFILIATED",7.865398536,0.035040766,{"v":6.63e-14,"d":"6.63E-14"},{"v":6.1e-15,"d":"6.10E-15"},0.01603064,23.04169452,"Up"]
[2764,"KEGG_PEROXISOME",7.842469444,0.049720694,{"v":7.89e-14,"d":"7.89E-14"},{"v":7.28e-15,"d":"7.28E-15"},-0.109196719,22.8680009,"Up"]
[2763,"REACTOME_BIOTIN_TRANSPORT_AND_METABOLISM",7.824447307,0.097405043,{"v":8.97e-14,"d":"8.97E-14"},{"v":8.37e-15,"d":"8.37E-15"},-0.127260951,22.73181235,"Up"]
[2762,"WP_PATHWAYS_OF_NUCLEIC_ACID_METABOLISM_AND_INNATE_IMMUNE_SENSING",7.740505602,0.103528771,{"v":1.69e-13,"d":"1.69E-13"},{"v":1.59e-14,"d":"1.59E-14"},-0.128178396,22.10136036,"Up"]
[2761,"REACTOME_ACETYLCHOLINE_INHIBITS_CONTRACTION_OF_OUTER_HAIR_CELLS",7.736012004,0.055469662,{"v":1.74e-13,"d":"1.74E-13"},{"v":1.65e-14,"d":"1.65E-14"},0.478578956,22.06779077,"Up"]
[2760,"WP_ZINC_HOMEOSTASIS",7.717644876,0.070718866,{"v":2e-13,"d":"2.00E-13"},{"v":1.89e-14,"d":"1.89E-14"},-0.166791417,21.93076881,"Up"]
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[2757,"REACTOME_GPVI_MEDIATED_ACTIVATION_CASCADE",7.677363695,0.090643379,{"v":2.68e-13,"d":"2.68E-13"},{"v":2.57e-14,"d":"2.57E-14"},-0.108757429,21.63133571,"Up"]
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[2753,"REACTOME_ADRENOCEPTORS",7.632891025,0.054455738,{"v":3.7e-13,"d":"3.70E-13"},{"v":3.6e-14,"d":"3.60E-14"},0.430521331,21.30245587,"Up"]
[2752,"WP_LINOLEIC_ACID_METABOLISM_AFFECTED_BY_CORONAVIRUS_INFECTION",7.613371028,0.126330262,{"v":4.25e-13,"d":"4.25E-13"},{"v":4.17e-14,"d":"4.17E-14"},0.01872114,21.15867104,"Up"]
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[2750,"REACTOME_STAT5_ACTIVATION",7.55559349,0.12139397,{"v":6.49e-13,"d":"6.49E-13"},{"v":6.42e-14,"d":"6.42E-14"},-0.228702839,20.73511107,"Up"]
[2749,"REACTOME_GLYCOSAMINOGLYCAN_METABOLISM",7.539181554,0.04206084,{"v":7.31e-13,"d":"7.31E-13"},{"v":7.26e-14,"d":"7.26E-14"},-0.137051899,20.61535132,"Up"]
[2748,"REACTOME_INITIAL_TRIGGERING_OF_COMPLEMENT",7.512086312,0.101015779,{"v":8.91e-13,"d":"8.91E-13"},{"v":8.88e-14,"d":"8.88E-14"},0.193042965,20.41817118,"Up"]
[2747,"REACTOME_MELANIN_BIOSYNTHESIS",7.504135777,0.059387102,{"v":9.42e-13,"d":"9.42E-13"},{"v":9.42e-14,"d":"9.42E-14"},0.261453305,20.36043973,"Up"]
[2746,"WP_FAMILIAL_HYPERLIPIDEMIA_TYPE_4",7.496109702,0.063012909,{"v":9.96e-13,"d":"9.96E-13"},{"v":1e-13,"d":"1.00E-13"},0.126483029,20.30221819,"Up"]
[2745,"WP_FARNESOID_X_RECEPTOR_PATHWAY",7.490297821,0.090129601,{"v":1.04e-12,"d":"1.04E-12"},{"v":1.04e-13,"d":"1.04E-13"},-0.03182541,20.2600952,"Up"]
[2744,"REACTOME_METABOLIC_DISORDERS_OF_BIOLOGICAL_OXIDATION_ENZYMES",7.486263211,0.058379002,{"v":1.06e-12,"d":"1.06E-12"},{"v":1.08e-13,"d":"1.08E-13"},0.089856608,20.23087151,"Up"]
[2743,"BIOCARTA_PML_PATHWAY",7.480631028,0.082017921,{"v":1.1e-12,"d":"1.10E-12"},{"v":1.12e-13,"d":"1.12E-13"},-0.173732555,20.19010103,"Up"]
[2742,"REACTOME_FRUCTOSE_CATABOLISM",7.460437562,0.106004045,{"v":1.28e-12,"d":"1.28E-12"},{"v":1.3e-13,"d":"1.30E-13"},0.060262917,20.04416158,"Up"]
[2741,"WP_DEVELOPMENT_OF_URETERIC_COLLECTION_SYSTEM",7.453309229,0.05648847,{"v":1.34e-12,"d":"1.34E-12"},{"v":1.37e-13,"d":"1.37E-13"},-0.119302841,19.99273352,"Up"]
[2740,"REACTOME_FRS_MEDIATED_FGFR2_SIGNALING",7.445377924,0.075204347,{"v":1.42e-12,"d":"1.42E-12"},{"v":1.45e-13,"d":"1.45E-13"},-0.153549494,19.93556684,"Up"]
[2739,"WP_7OXOC_AND_7BETAHC_PATHWAYS",7.437136323,0.071923341,{"v":1.5e-12,"d":"1.50E-12"},{"v":1.54e-13,"d":"1.54E-13"},-0.014295987,19.87622447,"Up"]
[2738,"WP_APOPTOSIS",7.406052994,0.049662326,{"v":1.88e-12,"d":"1.88E-12"},{"v":1.94e-13,"d":"1.94E-13"},-0.138004217,19.65297189,"Up"]
[2737,"REACTOME_NOTCH2_ACTIVATION_AND_TRANSMISSION_OF_SIGNAL_TO_THE_NUCLEUS",7.395959953,0.094361724,{"v":2.01e-12,"d":"2.01E-12"},{"v":2.09e-13,"d":"2.09E-13"},-0.189744633,19.58066956,"Up"]
[2736,"PID_SYNDECAN_1_PATHWAY",7.395396571,0.109927758,{"v":2.02e-12,"d":"2.02E-12"},{"v":2.1e-13,"d":"2.10E-13"},-0.13521788,19.57663647,"Up"]
[2735,"REACTOME_CONSTITUTIVE_SIGNALING_BY_ABERRANT_PI3K_IN_CANCER",7.361022673,0.045398133,{"v":2.57e-12,"d":"2.57E-12"},{"v":2.7e-13,"d":"2.70E-13"},-0.074982637,19.3311125,"Up"]
[2734,"REACTOME_DEFECTIVE_FACTOR_IX_CAUSES_HEMOPHILIA_B",7.354978046,0.148990165,{"v":2.68e-12,"d":"2.68E-12"},{"v":2.82e-13,"d":"2.82E-13"},0.003705093,19.28804899,"Up"]
[2733,"REACTOME_ECM_PROTEOGLYCANS",7.332477387,0.100496665,{"v":3.13e-12,"d":"3.13E-12"},{"v":3.32e-13,"d":"3.32E-13"},-0.094998986,19.12804213,"Up"]
[2732,"KEGG_HOMOLOGOUS_RECOMBINATION",7.328173451,0.068390354,{"v":3.22e-12,"d":"3.22E-12"},{"v":3.42e-13,"d":"3.42E-13"},-0.028624115,19.09748874,"Up"]
[2731,"REACTOME_SLC_TRANSPORTER_DISORDERS",7.315143095,0.038802069,{"v":3.52e-12,"d":"3.52E-12"},{"v":3.76e-13,"d":"3.76E-13"},-0.111984605,19.00509036,"Up"]
[2730,"REACTOME_TELOMERE_C_STRAND_LAGGING_STRAND_SYNTHESIS",7.306106419,0.069260568,{"v":3.75e-12,"d":"3.75E-12"},{"v":4.02e-13,"d":"4.02E-13"},-0.10962602,18.94110249,"Up"]
[2729,"REACTOME_ALTERNATIVE_COMPLEMENT_ACTIVATION",7.297527439,0.163545412,{"v":3.98e-12,"d":"3.98E-12"},{"v":4.28e-13,"d":"4.28E-13"},0.124906539,18.88042472,"Up"]
[2728,"REACTOME_TRANSPORT_OF_VITAMINS_NUCLEOSIDES_AND_RELATED_MOLECULES",7.282348151,0.051705627,{"v":4.43e-12,"d":"4.43E-12"},{"v":4.77e-13,"d":"4.77E-13"},-0.040588627,18.77322919,"Up"]
[2727,"REACTOME_MISCELLANEOUS_SUBSTRATES",7.266862265,0.064887837,{"v":4.93e-12,"d":"4.93E-12"},{"v":5.33e-13,"d":"5.33E-13"},0.33513496,18.66408603,"Up"]
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[2725,"NABA_ECM_REGULATORS",7.255988002,0.044043081,{"v":5.3e-12,"d":"5.30E-12"},{"v":5.77e-13,"d":"5.77E-13"},-0.077941243,18.58757654,"Up"]
[2724,"BIOCARTA_LAIR_PATHWAY",7.253933407,0.064939786,{"v":5.35e-12,"d":"5.35E-12"},{"v":5.85e-13,"d":"5.85E-13"},0.215541987,18.57313294,"Up"]
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[2721,"BIOCARTA_ACE2_PATHWAY",7.232897324,0.119215971,{"v":6.13e-12,"d":"6.13E-12"},{"v":6.81e-13,"d":"6.81E-13"},0.076364194,18.42547397,"Up"]
[2720,"REACTOME_NCAM_SIGNALING_FOR_NEURITE_OUT_GROWTH",7.230754834,0.080493568,{"v":6.2e-12,"d":"6.20E-12"},{"v":6.91e-13,"d":"6.91E-13"},-0.147458007,18.41045792,"Up"]
[2719,"KEGG_GLYCOSPHINGOLIPID_BIOSYNTHESIS_GANGLIO_SERIES",7.216978018,0.081645845,{"v":6.82e-12,"d":"6.82E-12"},{"v":7.63e-13,"d":"7.63E-13"},-0.14765171,18.31400111,"Up"]
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[2717,"REACTOME_GLYCEROPHOSPHOLIPID_BIOSYNTHESIS",7.20386706,0.034166347,{"v":7.43e-12,"d":"7.43E-12"},{"v":8.38e-13,"d":"8.38E-13"},-0.095563248,18.22236796,"Up"]
[2716,"WP_INFLAMMATORY_RESPONSE_PATHWAY",7.201147122,0.107732068,{"v":7.55e-12,"d":"7.55E-12"},{"v":8.54e-13,"d":"8.54E-13"},-0.032362819,18.20337794,"Up"]
[2715,"REACTOME_ANCHORING_FIBRIL_FORMATION",7.177153837,0.141818193,{"v":8.91e-12,"d":"8.91E-12"},{"v":1.01e-12,"d":"1.01E-12"},-0.135042118,18.03615619,"Up"]
[2714,"WP_MONOAMINE_TRANSPORT",7.169243297,0.068610071,{"v":9.39e-12,"d":"9.39E-12"},{"v":1.07e-12,"d":"1.07E-12"},-0.074185554,17.98113938,"Up"]
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[2712,"REACTOME_PLATELET_ADHESION_TO_EXPOSED_COLLAGEN",7.152427412,0.139310865,{"v":1.05e-11,"d":"1.05E-11"},{"v":1.21e-12,"d":"1.21E-12"},-0.122301034,17.86437801,"Up"]
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[2710,"REACTOME_FGFR2B_LIGAND_BINDING_AND_ACTIVATION",7.131712915,0.094686739,{"v":1.21e-11,"d":"1.21E-11"},{"v":1.4e-12,"d":"1.40E-12"},-0.084347223,17.72090378,"Up"]
[2709,"REACTOME_CD22_MEDIATED_BCR_REGULATION",7.079082589,0.054523008,{"v":1.73e-11,"d":"1.73E-11"},{"v":2.03e-12,"d":"2.03E-12"},0.343846791,17.35814676,"Up"]
[2708,"REACTOME_BLOOD_GROUP_SYSTEMS_BIOSYNTHESIS",7.077332147,0.053398442,{"v":1.75e-11,"d":"1.75E-11"},{"v":2.05e-12,"d":"2.05E-12"},0.332520065,17.34612556,"Up"]
[2707,"BIOCARTA_TH1TH2_PATHWAY",7.07368024,0.079341021,{"v":1.78e-11,"d":"1.78E-11"},{"v":2.11e-12,"d":"2.11E-12"},0.103883621,17.32105506,"Up"]
[2706,"REACTOME_METABOLISM_OF_WATER_SOLUBLE_VITAMINS_AND_COFACTORS",7.063993725,0.035159494,{"v":1.9e-11,"d":"1.90E-11"},{"v":2.26e-12,"d":"2.26E-12"},-0.101043668,17.25461618,"Up"]
[2705,"REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS",7.059679753,0.042851856,{"v":1.96e-11,"d":"1.96E-11"},{"v":2.33e-12,"d":"2.33E-12"},0.453725277,17.22505488,"Up"]
[2704,"WP_IRINOTECAN_PATHWAY",7.05677134,0.124582502,{"v":1.99e-11,"d":"1.99E-11"},{"v":2.37e-12,"d":"2.37E-12"},-0.033797463,17.20513477,"Up"]
[2703,"REACTOME_HS_GAG_DEGRADATION",7.055154207,0.071464391,{"v":2.01e-11,"d":"2.01E-11"},{"v":2.4e-12,"d":"2.40E-12"},-0.148417216,17.19406218,"Up"]
[2702,"REACTOME_FCERI_MEDIATED_MAPK_ACTIVATION",7.045677598,0.06464673,{"v":2.14e-11,"d":"2.14E-11"},{"v":2.57e-12,"d":"2.57E-12"},-0.121814913,17.12922379,"Up"]
[2701,"REACTOME_ERYTHROPOIETIN_ACTIVATES_PHOSPHOLIPASE_C_GAMMA_PLCG",7.040498476,0.127214114,{"v":2.21e-11,"d":"2.21E-11"},{"v":2.66e-12,"d":"2.66E-12"},-0.252585265,17.09382351,"Up"]
[2700,"PID_FAS_PATHWAY",7.034920723,0.056295602,{"v":2.29e-11,"d":"2.29E-11"},{"v":2.77e-12,"d":"2.77E-12"},-0.172231436,17.05572614,"Up"]
[2699,"REACTOME_PHOSPHATE_BOND_HYDROLYSIS_BY_NUDT_PROTEINS",6.988243269,0.10862014,{"v":3.16e-11,"d":"3.16E-11"},{"v":3.83e-12,"d":"3.83E-12"},-0.139283556,16.73803212,"Up"]
[2698,"PID_EPO_PATHWAY",6.950910869,0.057719978,{"v":4.06e-11,"d":"4.06E-11"},{"v":4.96e-12,"d":"4.96E-12"},-0.245113044,16.48538819,"Up"]
[2697,"WP_ARRHYTHMOGENIC_RIGHT_VENTRICULAR_CARDIOMYOPATHY",6.925606201,0.06180932,{"v":4.82e-11,"d":"4.82E-11"},{"v":5.91e-12,"d":"5.91E-12"},-0.124246672,16.3148724,"Up"]
[2696,"REACTOME_DISEASES_OF_CARBOHYDRATE_METABOLISM",6.913270552,0.078912865,{"v":5.22e-11,"d":"5.22E-11"},{"v":6.43e-12,"d":"6.43E-12"},-0.106654341,16.23196288,"Up"]
[2695,"BIOCARTA_EOSINOPHILS_PATHWAY",6.903146551,0.123893993,{"v":5.56e-11,"d":"5.56E-11"},{"v":6.89e-12,"d":"6.89E-12"},-0.22437475,16.16402316,"Up"]
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[2691,"REACTOME_MEIOTIC_RECOMBINATION",6.870343715,0.06204699,{"v":6.85e-11,"d":"6.85E-11"},{"v":8.63e-12,"d":"8.63E-12"},-0.106450645,15.94454193,"Up"]
[2690,"REACTOME_DOWNSTREAM_SIGNALING_OF_ACTIVATED_FGFR2",6.867313662,0.060181308,{"v":6.96e-11,"d":"6.96E-11"},{"v":8.81e-12,"d":"8.81E-12"},-0.185742193,15.92431827,"Up"]
[2689,"WP_IMMUNE_RESPONSE_TO_TUBERCULOSIS",6.86085911,0.072582235,{"v":7.25e-11,"d":"7.25E-11"},{"v":9.21e-12,"d":"9.21E-12"},-0.240477018,15.88126658,"Up"]
[2688,"REACTOME_KETONE_BODY_METABOLISM",6.800968662,0.093446064,{"v":1.08e-10,"d":"1.08E-10"},{"v":1.38e-11,"d":"1.38E-11"},-0.106425523,15.48363696,"Up"]
[2687,"REACTOME_SIGNALING_BY_RETINOIC_ACID",6.760325924,0.049250195,{"v":1.42e-10,"d":"1.42E-10"},{"v":1.82e-11,"d":"1.82E-11"},-0.134702204,15.21568992,"Up"]
[2686,"REACTOME_HEPARAN_SULFATE_HEPARIN_HS_GAG_METABOLISM",6.729169208,0.050211157,{"v":1.75e-10,"d":"1.75E-10"},{"v":2.25e-11,"d":"2.25E-11"},-0.076631675,15.01131836,"Up"]
[2685,"REACTOME_BASE_EXCISION_REPAIR_AP_SITE_FORMATION",6.706679554,0.073404507,{"v":2.03e-10,"d":"2.03E-10"},{"v":2.61e-11,"d":"2.61E-11"},-0.124759386,14.86435758,"Up"]
[2684,"REACTOME_RRNA_PROCESSING_IN_THE_MITOCHONDRION",6.678837718,0.101211157,{"v":2.43e-10,"d":"2.43E-10"},{"v":3.15e-11,"d":"3.15E-11"},-0.099515172,14.68307261,"Up"]
[2683,"REACTOME_TRAF3_DEPENDENT_IRF_ACTIVATION_PATHWAY",6.655192738,0.082270163,{"v":2.83e-10,"d":"2.83E-10"},{"v":3.68e-11,"d":"3.68E-11"},-0.252280687,14.5296795,"Up"]
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[2681,"REACTOME_METAL_ION_SLC_TRANSPORTERS",6.649375907,0.058135945,{"v":2.93e-10,"d":"2.93E-10"},{"v":3.83e-11,"d":"3.83E-11"},-0.19292022,14.4920233,"Up"]
[2680,"WP_OSTEOBLAST_SIGNALING",6.636161045,0.108550832,{"v":3.19e-10,"d":"3.19E-10"},{"v":4.18e-11,"d":"4.18E-11"},-0.150923447,14.40659158,"Up"]
[2679,"WP_NUCLEAR_RECEPTORS",6.624081873,0.053298641,{"v":3.42e-10,"d":"3.42E-10"},{"v":4.53e-11,"d":"4.53E-11"},-0.152812059,14.32864384,"Up"]
[2678,"WP_OVERVIEW_OF_INTERFERONSMEDIATED_SIGNALING_PATHWAY",6.623938635,0.074289999,{"v":3.42e-10,"d":"3.42E-10"},{"v":4.53e-11,"d":"4.53E-11"},-0.134631992,14.32772033,"Up"]
[2677,"REACTOME_DISEASES_OF_BASE_EXCISION_REPAIR",6.621951991,0.091554731,{"v":3.46e-10,"d":"3.46E-10"},{"v":4.59e-11,"d":"4.59E-11"},0.020504032,14.31491363,"Up"]
[2676,"PID_HIV_NEF_PATHWAY",6.617050502,0.056138372,{"v":3.56e-10,"d":"3.56E-10"},{"v":4.74e-11,"d":"4.74E-11"},-0.129199353,14.28333236,"Up"]
[2675,"KEGG_VALINE_LEUCINE_AND_ISOLEUCINE_DEGRADATION",6.602210662,0.052605703,{"v":3.92e-10,"d":"3.92E-10"},{"v":5.23e-11,"d":"5.23E-11"},-0.213488114,14.1878525,"Up"]
[2674,"REACTOME_PEROXISOMAL_PROTEIN_IMPORT",6.600563473,0.050798547,{"v":3.95e-10,"d":"3.95E-10"},{"v":5.29e-11,"d":"5.29E-11"},-0.113628047,14.17726708,"Up"]
[2673,"WP_VITAMIN_B12_DISORDERS",6.593091517,0.076868999,{"v":4.14e-10,"d":"4.14E-10"},{"v":5.56e-11,"d":"5.56E-11"},-0.033845426,14.12928131,"Up"]
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[2612,"WP_AMYOTROPHIC_LATERAL_SCLEROSIS_ALS",5.978738078,0.052869756,{"v":1.67e-08,"d":"1.67E-08"},{"v":2.68e-09,"d":"2.68E-09"},-0.131757345,10.36221165,"Up"]
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[2600,"WP_BMP_SIGNALING_IN_EYELID_DEVELOPMENT",5.825838715,0.068135711,{"v":3.97e-08,"d":"3.97E-08"},{"v":6.65e-09,"d":"6.65E-09"},-0.242564539,9.479724295,"Up"]
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[2597,"WP_APOE_AND_MIR146_IN_INFLAMMATION_AND_ATHEROSCLEROSIS",5.797887277,0.084029037,{"v":4.64e-08,"d":"4.64E-08"},{"v":7.84e-09,"d":"7.84E-09"},-0.214132501,9.320781615,"Up"]
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[2595,"REACTOME_AFLATOXIN_ACTIVATION_AND_DETOXIFICATION",5.748739223,0.077847883,{"v":6.14e-08,"d":"6.14E-08"},{"v":1.04e-08,"d":"1.04E-08"},-0.060211403,9.043096579,"Up"]
[2594,"REACTOME_XENOBIOTICS",5.736620155,0.067298232,{"v":6.56e-08,"d":"6.56E-08"},{"v":1.12e-08,"d":"1.12E-08"},0.144944664,8.974975096,"Up"]
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[2326,"REACTOME_SYNTHESIS_OF_LEUKOTRIENES_LT_AND_EOXINS_EX",3.867120044,0.035982472,0.000385732,0.00011381,0.12355275,0.146764065,"Up"]
[2325,"REACTOME_TOLL_LIKE_RECEPTOR_CASCADES",3.854277316,0.023988676,0.00040362,0.000119903,-0.147855222,0.097775444,"Up"]
[2324,"KEGG_VALINE_LEUCINE_AND_ISOLEUCINE_BIOSYNTHESIS",3.852583434,0.062267417,0.000405941,0.00012073,-0.242723759,0.091326102,"Up"]
[2323,"REACTOME_RUNX2_REGULATES_BONE_DEVELOPMENT",3.85205811,0.039085905,0.000406346,0.000120987,-0.221471487,0.089326532,"Up"]
[2322,"BIOCARTA_PEPI_PATHWAY",3.849370587,0.087777115,0.00040994,0.000122312,-0.258913945,0.079101069,"Up"]
[2321,"REACTOME_TRANSPORT_OF_BILE_SALTS_AND_ORGANIC_ACIDS_METAL_IONS_AND_AMINE_COMPOUNDS",3.845041443,0.022799783,0.000416176,0.000124474,-0.031594472,0.062644358,"Up"]
[2320,"REACTOME_INTERFERON_ALPHA_BETA_SIGNALING",3.843179693,0.039870548,0.000418851,0.000125415,-0.187415599,0.055572748,"Up"]
[2319,"WP_ACE_INHIBITOR_PATHWAY",3.836861085,0.044934784,0.000429203,0.00012866,0.141254432,0.031597505,"Up"]
[2318,"REACTOME_SHC_MEDIATED_CASCADE_FGFR1",3.833295759,0.041014304,0.000434937,0.000130525,-0.125783665,0.018086422,"Up"]
[2317,"BIOCARTA_MYOSIN_PATHWAY",3.831515497,0.052559355,0.000437092,0.000131466,-0.256442761,0.011344607,"Up"]
[2316,"BIOCARTA_FXR_PATHWAY",3.828044379,0.070165956,0.000442757,0.000133319,-0.203500543,-0.001791572,"Up"]
[2315,"PID_IL27_PATHWAY",3.822418443,0.035226326,0.0004524,0.000136375,-0.025603233,-0.023057592,"Up"]
[2314,"KEGG_ADIPOCYTOKINE_SIGNALING_PATHWAY",3.804977844,0.023262203,0.000484154,0.000146273,-0.151283399,-0.088787256,"Up"]
[2313,"BIOCARTA_ERAD_PATHWAY",3.797746112,0.04488799,0.000497831,0.000150573,-0.178346479,-0.115955185,"Up"]
[2312,"REACTOME_CILIUM_ASSEMBLY",3.786540812,0.023110069,0.000518904,0.000157471,-0.148004115,-0.157950326,"Up"]
[2311,"KEGG_HYPERTROPHIC_CARDIOMYOPATHY_HCM",3.778756018,0.029854026,0.000534677,0.000162438,-0.079210962,-0.18705416,"Up"]
[2310,"REACTOME_EGR2_AND_SOX10_MEDIATED_INITIATION_OF_SCHWANN_CELL_MYELINATION",3.776380318,0.038691674,0.000539164,0.000163983,-0.136037259,-0.195924077,"Up"]
[2309,"REACTOME_DUAL_INCISION_IN_GG_NER",3.770584542,0.037575179,0.000551136,0.00016781,-0.203737965,-0.217540146,"Up"]
[2308,"REACTOME_GP1B_IX_V_ACTIVATION_SIGNALLING",3.765977834,0.07855342,0.000559466,0.000170911,-0.175253615,-0.234698107,"Up"]
[2307,"REACTOME_WNT_MEDIATED_ACTIVATION_OF_DVL",3.759290512,0.062671258,0.000573255,0.00017551,-0.211019725,-0.259568665,"Up"]
[2306,"REACTOME_FOXO_MEDIATED_TRANSCRIPTION",3.758054598,0.033930636,0.000575439,0.000176372,-0.224235881,-0.264160335,"Up"]
[2305,"BIOCARTA_DREAM_PATHWAY",3.75696059,0.055563714,0.000577306,0.000177139,-0.221056219,-0.268223558,"Up"]
[2304,"PID_MYC_REPRESS_PATHWAY",3.751769114,0.030114794,0.000588659,0.000180821,-0.198487331,-0.287489165,"Up"]
[2303,"BIOCARTA_TPO_PATHWAY",3.749930456,0.04127346,0.000592311,0.000182142,-0.255053767,-0.294306141,"Up"]
[2302,"BIOCARTA_HER2_PATHWAY",3.749586778,0.039318792,0.000592468,0.00018239,-0.226610689,-0.295579994,"Up"]
[2301,"REACTOME_TP53_REGULATES_TRANSCRIPTION_OF_CELL_DEATH_GENES",3.744243817,0.029301425,0.000603802,0.000186286,-0.104898115,-0.315368996,"Up"]
[2300,"REACTOME_ACTIVATED_NTRK2_SIGNALS_THROUGH_PI3K",3.735831982,0.058468456,0.000622838,0.000192578,-0.203472265,-0.346467995,"Up"]
[2299,"KEGG_CALCIUM_SIGNALING_PATHWAY",3.726597148,0.014284204,0.000643821,0.000199717,0.028103524,-0.380530289,"Up"]
[2298,"PID_AR_TF_PATHWAY",3.712795949,0.032634517,0.000678237,0.00021085,-0.236152898,-0.431280561,"Up"]
[2297,"WP_NUCLEOTIDE_EXCISION_REPAIR",3.711419469,0.0309997,0.000681172,0.000211991,-0.21350656,-0.436332027,"Up"]
[2296,"REACTOME_REGULATION_OF_TP53_ACTIVITY_THROUGH_PHOSPHORYLATION",3.697496138,0.022732355,0.000717793,0.000223872,-0.16609929,-0.487324661,"Up"]
[2295,"WP_HIPPO_SIGNALING_REGULATION_PATHWAYS",3.68817745,0.025558712,0.000741197,0.00023217,-0.114782821,-0.521347773,"Up"]
[2294,"PID_IL6_7_PATHWAY",3.687714748,0.041213893,0.000741739,0.00023259,-0.190100331,-0.52303492,"Up"]
[2293,"KEGG_LYSOSOME",3.681547301,0.024615681,0.000758971,0.000238249,-0.167141898,-0.545503326,"Up"]
[2292,"WP_MICROGLIA_PATHOGEN_PHAGOCYTOSIS_PATHWAY",3.67957904,0.023827412,0.000763992,0.000240082,0.122634989,-0.552666026,"Up"]
[2291,"BIOCARTA_BLYMPHOCYTE_PATHWAY",3.677826971,0.04062953,0.000768396,0.000241725,0.093520175,-0.5590388,"Up"]
[2290,"WP_CHOLESTEROL_BIOSYNTHESIS_WITH_SKELETAL_DYSPLASIAS",3.659049682,0.053465642,0.000822114,0.000260009,-0.182807628,-0.627149277,"Up"]
[2289,"WP_MITOCHONDRIAL_COMPLEX_II_ASSEMBLY",3.654885872,0.057102866,0.000834589,0.000264235,-0.261103064,-0.642206012,"Up"]
[2288,"REACTOME_DNA_METHYLATION",3.64452525,0.047140208,0.000867771,0.000275033,0.040326748,-0.679597655,"Up"]
[2287,"REACTOME_NUCLEOTIDE_BIOSYNTHESIS",3.642196587,0.050597496,0.000873748,0.000277516,-0.199168536,-0.687987425,"Up"]
[2286,"PID_WNT_SIGNALING_PATHWAY",3.630931327,0.030933718,0.000909621,0.000289829,-0.071485585,-0.728499549,"Up"]
[2285,"BIOCARTA_RELA_PATHWAY",3.628042815,0.042662177,0.000918813,0.000293067,-0.157696837,-0.738867278,"Up"]
[2284,"PID_P38_ALPHA_BETA_DOWNSTREAM_PATHWAY",3.606814728,0.034368278,0.000993613,0.000317929,-0.20676653,-0.814811516,"Up"]
[2283,"BIOCARTA_FAS_PATHWAY",3.606451514,0.035319266,0.000993949,0.000318372,-0.181514461,-0.816107101,"Up"]
[2282,"REACTOME_FORMATION_OF_THE_EARLY_ELONGATION_COMPLEX",3.60078679,0.036356317,0.001014642,0.000325342,-0.234522895,-0.836296542,"Up"]
[2281,"WP_CANCER_IMMUNOTHERAPY_BY_CTLA4_BLOCKADE",3.597960313,0.050107838,0.001024578,0.000328873,-0.194005054,-0.846358577,"Up"]
[2280,"BIOCARTA_HES_PATHWAY",3.592571366,0.048735598,0.001043672,0.000335705,-0.072913166,-0.86552121,"Up"]
[2279,"REACTOME_ROLE_OF_PHOSPHOLIPIDS_IN_PHAGOCYTOSIS",3.58768651,0.033581997,0.001062169,0.000342012,-0.033658864,-0.882866851,"Up"]
[2278,"BIOCARTA_GPCR_PATHWAY",3.576437122,0.039352059,0.00110744,0.000356962,-0.202115222,-0.922723766,"Up"]
[2277,"REACTOME_PYROPTOSIS",3.575749698,0.042966889,0.001109176,0.000357895,-0.189354328,-0.925155324,"Up"]
[2276,"REACTOME_REGULATED_NECROSIS",3.567276515,0.038004336,0.00114183,0.000369585,-0.16285052,-0.955088833,"Up"]
[2275,"REACTOME_ACTIVATION_OF_PUMA_AND_TRANSLOCATION_TO_MITOCHONDRIA",3.563874897,0.044737907,0.001155436,0.000374378,-0.156345874,-0.967086134,"Up"]
[2274,"WP_3Q29_COPY_NUMBER_VARIATION_SYNDROME",3.558071779,0.026004808,0.00117986,0.000382689,-0.165423981,-0.987527315,"Up"]
[2273,"BIOCARTA_FIBRINOLYSIS_PATHWAY",3.550903522,0.062174442,0.001210988,0.000393194,-0.117226783,-1.012731744,"Up"]
[2272,"WP_NEOVASCULARISATION_PROCESSES",3.542535534,0.030383454,0.001245929,0.000405798,-0.22218012,-1.042091112,"Up"]
[2271,"KEGG_PYRIMIDINE_METABOLISM",3.538147327,0.023132501,0.001265373,0.000412557,-0.133750921,-1.057459958,"Up"]
[2270,"REACTOME_SYNTHESIS_OF_WYBUTOSINE_AT_G37_OF_TRNA_PHE",3.535410362,0.054535863,0.001277148,0.000416826,-0.135955823,-1.067036128,"Up"]
[2269,"PID_AMB2_NEUTROPHILS_PATHWAY",3.531264706,0.036847531,0.001295864,0.000423371,-0.1150524,-1.081527139,"Up"]
[2268,"REACTOME_TP53_REGULATES_TRANSCRIPTION_OF_SEVERAL_ADDITIONAL_CELL_DEATH_GENES_WHOSE_SPECIFIC_ROLES_IN_P53_DEPENDENT_APOPTOSIS_REMAIN_UNCERTAIN",3.526403326,0.041088042,0.001318371,0.000431168,-0.170260388,-1.09849856,"Up"]
[2267,"BIOCARTA_HIVNEF_PATHWAY",3.525628476,0.027115872,0.001320848,0.000432423,-0.172321685,-1.101201485,"Up"]
[2266,"REACTOME_POST_TRANSLATIONAL_PROTEIN_MODIFICATION",3.515845138,0.018746014,0.001365663,0.000448567,-0.162115137,-1.135278458,"Up"]
[2265,"REACTOME_RUNX1_REGULATES_TRANSCRIPTION_OF_GENES_INVOLVED_IN_WNT_SIGNALING",3.515723548,0.050213575,0.001365663,0.000448771,-0.041987739,-1.135701388,"Up"]
[2264,"KEGG_GLUTATHIONE_METABOLISM",3.515721564,0.029842902,0.001365663,0.000448774,-0.172944541,-1.135708288,"Up"]
[2263,"KEGG_NUCLEOTIDE_EXCISION_REPAIR",3.515626011,0.029300455,0.001365663,0.000448935,-0.215670302,-1.136040645,"Up"]
[2262,"REACTOME_SYNTHESIS_OF_PG",3.501656873,0.05305272,0.001437342,0.000472982,-0.207665904,-1.184532437,"Up"]
[2261,"BIOCARTA_IL22BP_PATHWAY",3.49199275,0.054123562,0.001488495,0.000490316,-0.195510075,-1.217968473,"Up"]
[2260,"PID_A6B1_A6B4_INTEGRIN_PATHWAY",3.487312471,0.036336626,0.00151153,0.000498922,-0.156480541,-1.234128561,"Up"]
[2259,"KEGG_PRIMARY_IMMUNODEFICIENCY",3.485760104,0.025741674,0.001518723,0.000501808,0.213873547,-1.239483854,"Up"]
[2258,"REACTOME_MOLECULES_ASSOCIATED_WITH_ELASTIC_FIBRES",3.480386295,0.045741855,0.001547741,0.000511917,-0.152901371,-1.258004027,"Up"]
[2257,"WP_REGULATION_OF_WNT_BCATENIN_SIGNALING_BY_SMALL_MOLECULE_COMPOUNDS",3.472208023,0.051604992,0.001593739,0.000527668,-0.162701099,-1.286135295,"Up"]
[2256,"WP_ATM_SIGNALING_PATHWAY",3.471805648,0.02585597,0.00159434,0.000528454,-0.146745352,-1.28751768,"Up"]
[2255,"REACTOME_PLASMA_LIPOPROTEIN_REMODELING",3.468096486,0.029521031,0.001613244,0.000535756,0.015359016,-1.300253297,"Up"]
[2254,"REACTOME_HYALURONAN_UPTAKE_AND_DEGRADATION",3.467253037,0.044453932,0.001616644,0.000537429,-0.147658398,-1.303147453,"Up"]
[2253,"BIOCARTA_HSP27_PATHWAY",3.463051302,0.035038009,0.001638619,0.000545839,-0.030799827,-1.317554646,"Up"]
[2252,"REACTOME_DISEASES_ASSOCIATED_WITH_GLYCOSYLATION_PRECURSOR_BIOSYNTHESIS",3.4456563,0.038013311,0.001740063,0.000581975,-0.254888299,-1.377016252,"Up"]
[2251,"KEGG_TRYPTOPHAN_METABOLISM",3.432002723,0.029209456,0.001826232,0.000611887,-0.041495411,-1.423481333,"Up"]
[2250,"KEGG_N_GLYCAN_BIOSYNTHESIS",3.431941256,0.026360887,0.001826232,0.000612025,-0.169753806,-1.423690102,"Up"]
[2249,"REACTOME_CHROMOSOME_MAINTENANCE",3.417748872,0.023223751,0.001920083,0.000644637,-0.127644242,-1.471794817,"Up"]
[2248,"REACTOME_SIGNALING_BY_KIT_IN_DISEASE",3.417692363,0.038389403,0.001920083,0.00064477,-0.21364809,-1.471985959,"Up"]
[2247,"WP_SPHINGOLIPID_METABOLISM_OVERVIEW",3.41255895,0.032576708,0.001948571,0.000656962,-0.155050464,-1.489336752,"Up"]
[2246,"WP_ONECARBON_METABOLISM",3.40220943,0.026341522,0.002019382,0.000682196,-0.058124796,-1.524239507,"Up"]
[2245,"WP_CAMKK2_PATHWAY",3.400676216,0.032429516,0.002028649,0.00068601,-0.206385696,-1.529401219,"Up"]
[2244,"REACTOME_CHREBP_ACTIVATES_METABOLIC_GENE_EXPRESSION",3.390773014,0.041176053,0.002098745,0.000711128,-0.16383388,-1.562685907,"Up"]
[2243,"REACTOME_SYNTHESIS_OF_PIPS_AT_THE_EARLY_ENDOSOME_MEMBRANE",3.379411232,0.034694102,0.002184726,0.000740997,-0.214137301,-1.600754751,"Up"]
[2242,"REACTOME_PI_3K_CASCADE_FGFR1",3.377101302,0.035454581,0.00220086,0.00074721,-0.112389275,-1.608478971,"Up"]
[2241,"REACTOME_SIGNALING_BY_NOTCH3",3.374232941,0.03164713,0.00222158,0.000754993,-0.148006223,-1.618063276,"Up"]
[2240,"BIOCARTA_SPPA_PATHWAY",3.367088651,0.036622178,0.00227508,0.000774707,-0.192539498,-1.641900131,"Up"]
[2239,"REACTOME_RNA_POLYMERASE_I_TRANSCRIPTION",3.351911711,0.028719731,0.002395649,0.000818184,-0.199822218,-1.692372162,"Up"]
[2238,"REACTOME_RNA_POLYMERASE_I_PROMOTER_ESCAPE",3.34858674,0.035147683,0.002422021,0.000828007,-0.132761954,-1.703399505,"Up"]
[2237,"REACTOME_DNA_REPAIR",3.346216048,0.015814293,0.0024394,0.000835077,-0.154025102,-1.711255357,"Up"]
[2236,"WP_TRANSCRIPTIONAL_CASCADE_REGULATING_ADIPOGENESIS",3.346044346,0.04234215,0.0024394,0.000835591,-0.229158349,-1.711824117,"Up"]
[2235,"REACTOME_REGULATION_OF_TP53_ACTIVITY",3.343999964,0.019286027,0.002454927,0.000841737,-0.205231097,-1.718593904,"Up"]
[2234,"WP_CYTOSOLIC_DNASENSING_PATHWAY",3.341865824,0.025102911,0.002468424,0.000848197,-0.154467122,-1.725656554,"Up"]
[2233,"REACTOME_APOPTOTIC_CLEAVAGE_OF_CELL_ADHESION_PROTEINS",3.341565711,0.052501266,0.002468424,0.000849109,-0.232318778,-1.726649378,"Up"]
[2232,"BIOCARTA_INSULIN_PATHWAY",3.337865057,0.037372844,0.002497185,0.000860431,-0.276682316,-1.738884547,"Up"]
[2231,"REACTOME_ACTIVATION_OF_THE_TFAP2_AP_2_FAMILY_OF_TRANSCRIPTION_FACTORS",3.33197272,0.03848356,0.002545371,0.000878749,-0.12920134,-1.758338238,"Up"]
[2230,"REACTOME_SMAC_XIAP_REGULATED_APOPTOTIC_RESPONSE",3.331184882,0.055307661,0.002547574,0.000881225,-0.219267502,-1.760936729,"Up"]
[2229,"REACTOME_ACTIVATION_OF_CASPASES_THROUGH_APOPTOSOME_MEDIATED_CLEAVAGE",3.331184826,0.05530766,0.002547574,0.000881225,-0.219267503,-1.760936915,"Up"]
[2228,"REACTOME_REGULATION_OF_INSULIN_LIKE_GROWTH_FACTOR_IGF_TRANSPORT_AND_UPTAKE_BY_INSULIN_LIKE_GROWTH_FACTOR_BINDING_PROTEINS_IGFBPS",3.330457813,0.030524037,0.002551712,0.000883516,-0.113958303,-1.763334252,"Up"]
[2227,"REACTOME_FORMATION_OF_TC_NER_PRE_INCISION_COMPLEX",3.328808431,0.033770529,0.002564288,0.000888734,-0.232512686,-1.768771196,"Up"]
[2226,"WP_TCELL_ACTIVATION_SARSCOV2",3.328037377,0.022159078,0.002568508,0.000891184,-0.116890149,-1.771311947,"Up"]
[2225,"BIOCARTA_RANKL_PATHWAY",3.318437883,0.043958058,0.002650554,0.000922203,-0.201928208,-1.80289518,"Up"]
[2224,"WP_HEPATITIS_B_INFECTION",3.313945127,0.021532887,0.002688154,0.000937063,-0.208354419,-1.817645786,"Up"]
[2223,"WP_HEMATOPOIETIC_STEM_CELL_DIFFERENTIATION",3.313935042,0.021117194,0.002688154,0.000937096,0.013312187,-1.817678877,"Up"]
[2222,"WP_PREGNANE_X_RECEPTOR_PATHWAY",3.312749651,0.037798229,0.0026969,0.000941054,-0.180679676,-1.821567443,"Up"]
[2221,"REACTOME_DAP12_SIGNALING",3.307645851,0.036562442,0.002743593,0.000958271,-0.174831329,-1.838294289,"Up"]
[2220,"REACTOME_FGFR2_ALTERNATIVE_SPLICING",3.303996123,0.038675788,0.002776677,0.000970761,-0.242249332,-1.850240024,"Up"]
[2219,"REACTOME_TERMINATION_OF_TRANSLESION_DNA_SYNTHESIS",3.302677921,0.035002911,0.002787001,0.00097531,-0.194826573,-1.854551357,"Up"]
[2218,"PID_IL1_PATHWAY",3.302107078,0.029502167,0.002789962,0.000977285,-0.214810322,-1.856417837,"Up"]
[2217,"REACTOME_PTK6_REGULATES_PROTEINS_INVOLVED_IN_RNA_PROCESSING",3.299164981,0.069039291,0.002814052,0.000987527,-0.000872703,-1.866032532,"Up"]
[2216,"BIOCARTA_CREB_PATHWAY",3.299138563,0.036663162,0.002814052,0.000987619,-0.254781222,-1.866118827,"Up"]
[2215,"REACTOME_DISEASES_OF_MISMATCH_REPAIR_MMR",3.294592581,0.052812958,0.002856963,0.001003642,-0.266139414,-1.880958195,"Up"]
[2214,"KEGG_ASCORBATE_AND_ALDARATE_METABOLISM",3.293059169,0.0437412,0.002869749,0.0010091,-0.056005241,-1.885959122,"Up"]
[2213,"REACTOME_STAT3_NUCLEAR_EVENTS_DOWNSTREAM_OF_ALK_SIGNALING",3.291824789,0.046101321,0.002878487,0.001013514,-0.241775403,-1.889983141,"Up"]
[2212,"WP_PHYSIOLOGICAL_AND_PATHOLOGICAL_HYPERTROPHY_OF_THE_HEART",3.291658113,0.044391926,0.002878487,0.001014112,-0.166422258,-1.89052638,"Up"]
[2211,"REACTOME_SIGNALING_BY_FGFR3_FUSIONS_IN_CANCER",3.28744355,0.047435062,0.002916096,0.001029326,-0.298581889,-1.904253726,"Up"]
[2210,"PID_AVB3_INTEGRIN_PATHWAY",3.286838807,0.040141742,0.002919544,0.001031526,-0.171822223,-1.906222021,"Up"]
[2209,"REACTOME_NON_INTEGRIN_MEMBRANE_ECM_INTERACTIONS",3.284799564,0.041644928,0.002937834,0.001038978,-0.136953068,-1.912856633,"Up"]
[2208,"REACTOME_TRANSLESION_SYNTHESIS_BY_Y_FAMILY_DNA_POLYMERASES_BYPASSES_LESIONS_ON_DNA_TEMPLATE",3.279196465,0.032746692,0.002993607,0.001059711,-0.18993366,-1.931065178,"Up"]
[2207,"KEGG_MELANOGENESIS",3.27673605,0.020073834,0.003013931,0.001068935,-0.13421331,-1.939051143,"Up"]
[2206,"PID_TXA2PATHWAY",3.272883728,0.024208908,0.003049283,0.001083528,-0.08934463,-1.951543028,"Up"]
[2205,"REACTOME_PRESYNAPTIC_DEPOLARIZATION_AND_CALCIUM_CHANNEL_OPENING",3.266217304,0.030566828,0.003117123,0.001109216,0.146978043,-1.973125846,"Up"]
[2204,"REACTOME_PKA_MEDIATED_PHOSPHORYLATION_OF_CREB",3.266084523,0.037790382,0.003117123,0.001109734,-0.203773458,-1.973555288,"Up"]
[2203,"REACTOME_SYNDECAN_INTERACTIONS",3.265746764,0.055642485,0.003117873,0.001111051,-0.202464151,-1.974647594,"Up"]
[2202,"REACTOME_HCMV_LATE_EVENTS",3.261854289,0.026324696,0.003157679,0.001126333,-0.208502433,-1.987227722,"Up"]
[2201,"PID_BMP_PATHWAY",3.261420208,0.027984352,0.003157679,0.001128049,-0.222749851,-1.988629713,"Up"]
[2200,"KEGG_NATURAL_KILLER_CELL_MEDIATED_CYTOTOXICITY",3.261234623,0.018292935,0.003157679,0.001128784,-0.095412105,-1.98922906,"Up"]
[2199,"BIOCARTA_NPP1_PATHWAY",3.249016109,0.053982249,0.003287458,0.001178126,0.007227158,-2.028614398,"Up"]
[2198,"WP_NANOMATERIALINDUCED_INFLAMMASOME_ACTIVATION",3.247257613,0.053580721,0.00330462,0.001185389,-0.222514422,-2.034270723,"Up"]
[2197,"WP_OVARIAN_INFERTILITY",3.244845677,0.029722298,0.003329454,0.001195419,-0.105986338,-2.042023961,"Up"]
[2196,"WP_AMPACTIVATED_PROTEIN_KINASE_AMPK_SIGNALING",3.242135673,0.018913703,0.003351669,0.001206782,-0.168844103,-2.05072855,"Up"]
[2195,"WP_PI3KAKT_SIGNALING_PATHWAY",3.240507773,0.018958124,0.003367609,0.001213655,-0.124349135,-2.055953938,"Up"]
[2194,"WP_NUCLEOTIDE_EXCISION_REPAIR_IN_XERODERMA_PIGMENTOSUM",3.239989578,0.023909988,0.003370551,0.001215851,-0.205977566,-2.057616746,"Up"]
[2193,"KEGG_DILATED_CARDIOMYOPATHY",3.238533173,0.02595912,0.003384552,0.001222041,-0.08312939,-2.062288714,"Up"]
[2192,"WP_OSTEOBLAST_DIFFERENTIATION_AND_RELATED_DISEASES",3.234650786,0.016984185,0.003427453,0.001238686,-0.100336567,-2.074732787,"Up"]
[2191,"REACTOME_DEFECTIVE_CHST3_CAUSES_SEDCJD",3.229934034,0.053607441,0.003474472,0.001259189,0.060212681,-2.089831358,"Up"]
[2190,"WP_TRYPTOPHAN_METABOLISM",3.229644885,0.02526075,0.003474739,0.001260456,-0.053242428,-2.090756229,"Up"]
[2189,"BIOCARTA_GLEEVEC_PATHWAY",3.20989345,0.035536479,0.003717721,0.001349849,-0.285788206,-2.15373929,"Up"]
[2188,"REACTOME_SIGNALING_BY_MET",3.20932162,0.033047937,0.003721631,0.001352523,-0.177750569,-2.155557041,"Up"]
[2187,"REACTOME_RUNX1_REGULATES_EXPRESSION_OF_COMPONENTS_OF_TIGHT_JUNCTIONS",3.207179966,0.066730035,0.003745827,0.001362578,-0.244367967,-2.162362147,"Up"]
[2186,"BIOCARTA_STEM_PATHWAY",3.194606955,0.033168883,0.003904739,0.001423014,0.088456357,-2.202222248,"Up"]
[2185,"WP_STING_PATHWAY_IN_KAWASAKILIKE_DISEASE_AND_COVID19",3.189208828,0.032330551,0.003967002,0.001449713,-0.102513841,-2.219288353,"Up"]
[2184,"REACTOME_ADP_SIGNALLING_THROUGH_P2Y_PURINOCEPTOR_1",3.188447608,0.036719182,0.003973743,0.001453515,-0.096612338,-2.221692644,"Up"]
[2183,"REACTOME_NOTCH1_INTRACELLULAR_DOMAIN_REGULATES_TRANSCRIPTION",3.168334796,0.029822433,0.004245918,0.001557361,-0.17760062,-2.285012598,"Up"]
[2182,"REACTOME_PHASE_II_CONJUGATION_OF_COMPOUNDS",3.166398741,0.018166308,0.004266297,0.00156771,-0.055391338,-2.291086843,"Up"]
[2181,"WP_INITIATION_OF_TRANSCRIPTION_AND_TRANSLATION_ELONGATION_AT_THE_HIV1_LTR",3.165507322,0.029227202,0.004275403,0.001572496,-0.278993587,-2.293882377,"Up"]
[2180,"BIOCARTA_PLC_PATHWAY",3.164238437,0.047255634,0.004290061,0.001579332,-0.24615691,-2.297860322,"Up"]
[2179,"REACTOME_PP2A_MEDIATED_DEPHOSPHORYLATION_OF_KEY_METABOLIC_FACTORS",3.163613885,0.049397634,0.004295299,0.001582707,-0.177942298,-2.299817706,"Up"]
[2178,"WP_ESTROGEN_RECEPTOR_PATHWAY",3.159323595,0.039739299,0.00435075,0.00160607,-0.15103635,-2.313253407,"Up"]
[2177,"REACTOME_LAMININ_INTERACTIONS",3.155001633,0.041238309,0.00441135,0.001629926,-0.151166545,-2.326770052,"Up"]
[2176,"REACTOME_SYNTHESIS_OF_LIPOXINS_LX",3.148997879,0.031223055,0.004494314,0.001663608,0.224340517,-2.345516002,"Up"]
[2175,"PID_P73PATHWAY",3.13944359,0.021068713,0.00463426,0.001718531,-0.175574816,-2.375275178,"Up"]
[2174,"WP_INTERFERON_TYPE_I_SIGNALING_PATHWAYS",3.139067999,0.027057223,0.004635962,0.001720724,-0.179498111,-2.376443219,"Up"]
[2173,"WP_CEREBRAL_ORGANIC_ACIDURIAS_INCLUDING_DISEASES",3.138232256,0.05208612,0.004644918,0.001725613,-0.180360984,-2.379041781,"Up"]
[2172,"WP_WNTBETACATENIN_SIGNALING_PATHWAY_IN_LEUKEMIA",3.137029177,0.031761025,0.004659697,0.001732673,-0.160743784,-2.382781293,"Up"]
[2171,"REACTOME_RNA_POLYMERASE_II_TRANSCRIPTION",3.132674753,0.015019574,0.004724734,0.001758448,-0.140046364,-2.396304218,"Up"]
[2170,"REACTOME_SIGNALING_BY_FGFR3",3.125562862,0.029263632,0.00482678,0.001801304,-0.207480681,-2.418350641,"Up"]
[2169,"PID_WNT_CANONICAL_PATHWAY",3.118080575,0.032440126,0.004941455,0.001847428,-0.14768648,-2.441491731,"Up"]
[2168,"REACTOME_SENSING_OF_DNA_DOUBLE_STRAND_BREAKS",3.115849398,0.045737775,0.004969847,0.001861391,-0.285391339,-2.448381651,"Up"]
[2167,"WP_AMPLIFICATION_AND_EXPANSION_OF_ONCOGENIC_PATHWAYS_AS_METASTATIC_TRAITS",3.09876687,0.038442439,0.005249808,0.001971551,-0.151846241,-2.500971064,"Up"]
[2166,"REACTOME_SIGNALING_BY_ERBB4",3.093963624,0.02662985,0.005325882,0.002003588,-0.167679114,-2.515706543,"Up"]
[2165,"PID_INTEGRIN_A9B1_PATHWAY",3.093945663,0.031841871,0.005325882,0.002003708,-0.072507306,-2.515761602,"Up"]
[2164,"REACTOME_SIGNALING_BY_FGFR4",3.088832697,0.029043496,0.005413079,0.002038337,-0.213504051,-2.531422291,"Up"]
[2163,"WP_BLOOD_CLOTTING_CASCADE",3.086882695,0.035169439,0.00544162,0.002051688,0.008234143,-2.537388269,"Up"]
[2162,"BIOCARTA_MTA3_PATHWAY",3.086728098,0.037751931,0.00544162,0.00205275,-0.183586355,-2.537861092,"Up"]
[2161,"BIOCARTA_TOLL_PATHWAY",3.080257005,0.033178253,0.005555695,0.002097654,-0.200708587,-2.557631511,"Up"]
[2160,"WP_FACTORS_AND_PATHWAYS_AFFECTING_INSULINLIKE_GROWTH_FACTOR_IGF1AKT_SIGNALING",3.062340463,0.029822147,0.00588704,0.002226725,-0.184655281,-2.612155624,"Up"]
[2159,"REACTOME_PHASE_1_INACTIVATION_OF_FAST_NA_CHANNELS",3.056611372,0.019307485,0.005994816,0.002269509,0.360841909,-2.629524096,"Up"]
[2158,"REACTOME_A_TETRASACCHARIDE_LINKER_SEQUENCE_IS_REQUIRED_FOR_GAG_SYNTHESIS",3.050590746,0.030749408,0.006110287,0.002315282,-0.116792068,-2.647741686,"Up"]
[2157,"REACTOME_REGULATION_OF_PYRUVATE_DEHYDROGENASE_PDH_COMPLEX",3.049549212,0.030442441,0.006125964,0.002323286,-0.263761818,-2.650889617,"Up"]
[2156,"WP_CILIARY_LANDSCAPE",3.045226454,0.020697377,0.006208757,0.002356776,-0.181323893,-2.663943333,"Up"]
[2155,"REACTOME_GLYCOGEN_STORAGE_DISEASES",3.042766586,0.056831169,0.006248393,0.002376031,-0.110786391,-2.671363375,"Up"]
[2154,"REACTOME_ACTIVATION_OF_THE_PRE_REPLICATIVE_COMPLEX",3.04208169,0.023930996,0.006257017,0.002381418,-0.049220695,-2.673428262,"Up"]
[2153,"REACTOME_INTERLEUKIN_6_FAMILY_SIGNALING",3.03093704,0.034220256,0.006474296,0.002470656,-0.137811779,-2.706963523,"Up"]
[2152,"REACTOME_FLT3_SIGNALING_THROUGH_SRC_FAMILY_KINASES",3.029561022,0.056374496,0.006497984,0.002481884,-0.029437426,-2.711095631,"Up"]
[2151,"REACTOME_TRANSPORT_OF_ORGANIC_ANIONS",3.022687399,0.03921458,0.006629132,0.002538674,-0.0236249,-2.731708921,"Up"]
[2150,"WP_FTO_OBESITY_VARIANT_MECHANISM",3.020642998,0.046561132,0.006662034,0.002555793,-0.152330473,-2.737830924,"Up"]
[2149,"REACTOME_ADVANCED_GLYCOSYLATION_ENDPRODUCT_RECEPTOR_SIGNALING",3.020618813,0.045878062,0.006662034,0.002555996,-0.186862187,-2.737903321,"Up"]
[2147,"WP_INSULIN_SIGNALING_IN_ADIPOCYTES_DIABETIC_CONDITION",3.020112867,0.041026399,0.006662034,0.002560249,-0.242395203,-2.739417743,"Up"]
[2148,"WP_INSULIN_SIGNALING_IN_ADIPOCYTES_NORMAL_CONDITION",3.020112867,0.041026399,0.006662034,0.002560249,-0.242395203,-2.739417743,"Up"]
[2146,"REACTOME_NEF_AND_SIGNAL_TRANSDUCTION",3.018436865,0.04922545,0.00669295,0.002574385,0.0521733,-2.744432632,"Up"]
[2145,"WP_MYOMETRIAL_RELAXATION_AND_CONTRACTION_PATHWAYS",3.015033338,0.020829031,0.006755499,0.00260331,-0.10594961,-2.754608095,"Up"]
[2144,"WP_SMC1SMC3_ROLE_IN_DNA_DAMAGE_CORNELIA_DE_LANGE_SYNDROME",3.014804005,0.045067904,0.006755499,0.00260527,-0.195849084,-2.755293319,"Up"]
[2143,"WP_INTRACELLULAR_TRAFFICKING_PROTEINS_INVOLVED_IN_CMT_NEUROPATHY",3.009180938,0.033824333,0.006875188,0.002653744,-0.17511,-2.772078321,"Up"]
[2142,"WP_BMP2WNT4FOXO1_PATHWAY_IN_PRIMARY_ENDOMETRIAL_STROMAL_CELL_DIFFERENTIATION",3.006675735,0.038692873,0.006919748,0.002675605,-0.151145882,-2.779546425,"Up"]
[2141,"REACTOME_METABOLISM_OF_CARBOHYDRATES",2.992439098,0.013418746,0.007242892,0.002802994,-0.158162442,-2.821869363,"Up"]
[2140,"REACTOME_HOMOLOGY_DIRECTED_REPAIR",2.991844878,0.016653335,0.007244333,0.002808429,-0.128685503,-2.823631545,"Up"]
[2139,"REACTOME_PURINERGIC_SIGNALING_IN_LEISHMANIASIS_INFECTION",2.987998608,0.032779883,0.007329324,0.002843847,-0.15866759,-2.835029421,"Up"]
[2138,"BIOCARTA_LYMPHOCYTE_PATHWAY",2.983946801,0.033867823,0.007420178,0.002881598,0.163932903,-2.847020666,"Up"]
[2137,"REACTOME_ARYL_HYDROCARBON_RECEPTOR_SIGNALLING",2.973148383,0.058275416,0.007663543,0.002984455,-0.233749638,-2.878899646,"Up"]
[2136,"REACTOME_INHIBITION_OF_REPLICATION_INITIATION_OF_DAMAGED_DNA_BY_RB1_E2F1",2.972944073,0.040856137,0.007663543,0.002986433,-0.228900395,-2.879501703,"Up"]
[2135,"REACTOME_CARGO_TRAFFICKING_TO_THE_PERICILIARY_MEMBRANE",2.971216742,0.026970679,0.007699924,0.003003204,-0.165812924,-2.884590146,"Up"]
[2134,"KEGG_ARGININE_AND_PROLINE_METABOLISM",2.968776388,0.018019555,0.007754352,0.003027044,-0.070605665,-2.89177404,"Up"]
[2133,"KEGG_FC_GAMMA_R_MEDIATED_PHAGOCYTOSIS",2.960213311,0.021210508,0.007957948,0.003112071,-0.137318792,-2.916935699,"Up"]
[2132,"REACTOME_NOTCH3_INTRACELLULAR_DOMAIN_REGULATES_TRANSCRIPTION",2.959871238,0.031429518,0.007957948,0.003115513,-0.15742187,-2.917939348,"Up"]
[2131,"REACTOME_NUCLEOTIDE_BINDING_DOMAIN_LEUCINE_RICH_REPEAT_CONTAINING_RECEPTOR_NLR_SIGNALING_PATHWAYS",2.959699425,0.027237911,0.007957948,0.003117243,-0.150264233,-2.918443407,"Up"]
[2130,"REACTOME_UBIQUINOL_BIOSYNTHESIS",2.95707282,0.034734104,0.008018844,0.003143797,-0.104058608,-2.926145638,"Up"]
[2129,"WP_TP53_NETWORK",2.956672992,0.032282889,0.008022308,0.003147858,-0.197848398,-2.927317497,"Up"]
[2128,"REACTOME_SIGNALING_BY_EGFR",2.954965297,0.025975902,0.008059722,0.003165253,-0.215854477,-2.932320817,"Up"]
[2127,"PID_INTEGRIN_A4B1_PATHWAY",2.954269848,0.032117825,0.008070903,0.003172362,-0.194218559,-2.934357571,"Up"]
[2126,"WP_GLIOBLASTOMA_SIGNALING_PATHWAYS",2.95093606,0.02149949,0.008147917,0.003206645,-0.239141519,-2.944114603,"Up"]
[2125,"WP_NONGENOMIC_ACTIONS_OF_125_DIHYDROXYVITAMIN_D3",2.940860214,0.019459784,0.008390536,0.003312323,-0.157778961,-2.97353733,"Up"]
[2124,"WP_PROSTAGLANDIN_SIGNALING",2.940613136,0.022469628,0.008390536,0.003314954,-0.03177903,-2.974257577,"Up"]
[2123,"REACTOME_NEDDYLATION",2.939039506,0.023889563,0.008425877,0.003331755,-0.176998138,-2.978843388,"Up"]
[2122,"REACTOME_REGULATION_OF_TP53_ACTIVITY_THROUGH_ASSOCIATION_WITH_CO_FACTORS",2.935336073,0.029574652,0.008519388,0.0033716,-0.200860661,-2.989626186,"Up"]
[2121,"REACTOME_RAB_REGULATION_OF_TRAFFICKING",2.932898389,0.018643819,0.008571666,0.003398064,-0.190498358,-2.996716317,"Up"]
[2120,"REACTOME_PROCESSING_OF_DNA_DOUBLE_STRAND_BREAK_ENDS",2.926573225,0.021258995,0.008732273,0.003467615,-0.138074823,-3.015086162,"Up"]
[2119,"PID_NEPHRIN_NEPH1_PATHWAY",2.923038768,0.030793705,0.008809144,0.003507042,-0.20256155,-3.025333983,"Up"]
[2118,"WP_NOTCH_SIGNALING",2.920382004,0.021518942,0.008869253,0.003536947,-0.223702553,-3.033028939,"Up"]
[2117,"REACTOME_DEFECTIVE_CSF2RB_CAUSES_SMDP5",2.918070701,0.014751154,0.008927425,0.003563152,0.36244223,-3.03971767,"Up"]
[2116,"WP_THYROID_HORMONES_PRODUCTION_AND_PERIPHERAL_DOWNSTREAM_SIGNALING_EFFECTS",2.910629485,0.018933213,0.009103411,0.003648723,-0.199075384,-3.061216327,"Up"]
[2115,"REACTOME_NOTCH4_INTRACELLULAR_DOMAIN_REGULATES_TRANSCRIPTION",2.910159739,0.031172266,0.009109389,0.003654187,-0.109457115,-3.06257166,"Up"]
[2114,"REACTOME_PRC2_METHYLATES_HISTONES_AND_DNA",2.908752674,0.034630497,0.009142625,0.003670599,-0.266120794,-3.066630089,"Up"]
[2113,"REACTOME_DNA_DAMAGE_BYPASS",2.900438281,0.027318833,0.009379735,0.003768954,-0.201613942,-3.090571776,"Up"]
[2112,"REACTOME_NRIF_SIGNALS_CELL_DEATH_FROM_THE_NUCLEUS",2.895232648,0.045631981,0.009528023,0.003831748,-0.169402361,-3.105527062,"Up"]
[2111,"REACTOME_ANTIVIRAL_MECHANISM_BY_IFN_STIMULATED_GENES",2.889839487,0.024905811,0.00966799,0.003897806,-0.220490619,-3.120993011,"Up"]
[2110,"KEGG_NON_SMALL_CELL_LUNG_CANCER",2.886088804,0.020689606,0.009775282,0.003944354,-0.226286789,-3.131731981,"Up"]
[2109,"BIOCARTA_TCRA_PATHWAY",2.87717046,0.026296003,0.010046245,0.004057072,0.234953193,-3.157211494,"Up"]
[2108,"REACTOME_GLUTATHIONE_SYNTHESIS_AND_RECYCLING",2.876744826,0.028943682,0.010051363,0.004062524,-0.079083306,-3.158425564,"Up"]
[2107,"WP_INTERLEUKIN1_INDUCED_ACTIVATION_OF_NFKB",2.87305404,0.041457507,0.010160556,0.00411008,-0.195417125,-3.168945646,"Up"]
[2106,"REACTOME_ROLE_OF_LAT2_NTAL_LAB_ON_CALCIUM_MOBILIZATION",2.870156584,0.026989607,0.010245192,0.004147767,-0.070688132,-3.177195066,"Up"]
[2105,"WP_CONSTITUTIVE_ANDROSTANE_RECEPTOR_PATHWAY",2.865849266,0.032453271,0.010376378,0.004204373,-0.198620299,-3.189443287,"Up"]
[2104,"REACTOME_SIGNALING_BY_FGFR2",2.861062864,0.024968603,0.010516164,0.004268096,-0.213234402,-3.203032433,"Up"]
[2103,"REACTOME_CD28_DEPENDENT_PI3K_AKT_SIGNALING",2.852280405,0.031743612,0.010783036,0.004387305,-0.211749219,-3.227908271,"Up"]
[2102,"REACTOME_MYOCLONIC_EPILEPSY_OF_LAFORA",2.845375972,0.068031892,0.011000351,0.004483134,-0.116912568,-3.247411463,"Up"]
[2101,"REACTOME_ACTIVATION_OF_THE_AP_1_FAMILY_OF_TRANSCRIPTION_FACTORS",2.84420427,0.0420551,0.011031596,0.004499583,-0.263453944,-3.250716559,"Up"]
[2100,"REACTOME_LINOLEIC_ACID_LA_METABOLISM",2.842882365,0.029597921,0.011063124,0.004518207,-0.026554052,-3.254443721,"Up"]
[2099,"REACTOME_NR1H2_NR1H3_REGULATE_GENE_EXPRESSION_LINKED_TO_LIPOGENESIS",2.842625172,0.038537809,0.011063124,0.004521839,-0.240968284,-3.255168688,"Up"]
[2098,"BIOCARTA_TCR_PATHWAY",2.84042671,0.026139471,0.011125784,0.00455299,-0.144110945,-3.261362976,"Up"]
[2097,"REACTOME_ACTIVATED_PKN1_STIMULATES_TRANSCRIPTION_OF_AR_ANDROGEN_RECEPTOR_REGULATED_GENES_KLK2_AND_KLK3",2.83748853,0.047546091,0.011219026,0.004594926,-0.350594227,-3.269634041,"Up"]
[2096,"REACTOME_INTRAFLAGELLAR_TRANSPORT",2.835795272,0.026595993,0.011269154,0.004619253,-0.170405887,-3.274396758,"Up"]
[2095,"REACTOME_CELL_DEATH_SIGNALLING_VIA_NRAGE_NRIF_AND_NADE",2.833653729,0.019917696,0.011328476,0.004650186,-0.133085367,-3.280416353,"Up"]
[2094,"REACTOME_SIGNALING_BY_INSULIN_RECEPTOR",2.828239227,0.018201278,0.011509099,0.004729236,-0.200598845,-3.295615692,"Up"]
[2093,"REACTOME_TELOMERE_MAINTENANCE",2.819068827,0.021239471,0.01183199,0.004865901,-0.16374546,-3.321292653,"Up"]
[2092,"WP_DNA_IRDAMAGE_AND_CELLULAR_RESPONSE_VIA_ATR",2.817291662,0.015847091,0.011887651,0.004892795,-0.165664218,-3.326259118,"Up"]
[2091,"REACTOME_NITRIC_OXIDE_STIMULATES_GUANYLATE_CYCLASE",2.814909259,0.022815667,0.01196597,0.004929061,0.204169223,-3.332912107,"Up"]
[2090,"WP_MAMMALIAN_DISORDER_OF_SEXUAL_DEVELOPMENT",2.813466325,0.037869474,0.011999955,0.004951143,-0.123925425,-3.336938866,"Up"]
[2089,"REACTOME_SIGNALING_BY_FLT3_ITD_AND_TKD_MUTANTS",2.809379004,0.032636202,0.012142829,0.005014183,-0.285061796,-3.348334131,"Up"]
[2088,"PID_HNF3A_PATHWAY",2.807796795,0.028396955,0.012182522,0.00503878,-0.165663416,-3.352740844,"Up"]
[2087,"REACTOME_BBSOME_MEDIATED_CARGO_TARGETING_TO_CILIUM",2.80418811,0.034726481,0.012309125,0.005095289,-0.118722746,-3.362782422,"Up"]
[2086,"WP_NOTCH1_REGULATION_OF_ENDOTHELIAL_CELL_CALCIFICATION",2.802987684,0.038709949,0.012326906,0.005114214,-0.158319771,-3.366119905,"Up"]
[2085,"REACTOME_PRE_NOTCH_PROCESSING_IN_THE_ENDOPLASMIC_RETICULUM",2.802931231,0.045923719,0.012326906,0.005115105,-0.195232211,-3.366276823,"Up"]
[2084,"REACTOME_INOSITOL_PHOSPHATE_METABOLISM",2.80169154,0.019542733,0.012364136,0.005134719,-0.117529637,-3.369721916,"Up"]
[2083,"WP_PHOTODYNAMIC_THERAPYINDUCED_AP1_SURVIVAL_SIGNALING",2.798049868,0.025233932,0.012493458,0.005192728,-0.170861471,-3.379833357,"Up"]
[2082,"WP_PYRIMIDINE_METABOLISM",2.797793082,0.019452084,0.012493458,0.005196841,-0.134435925,-3.380545855,"Up"]
[2081,"REACTOME_TRANSCRIPTION_COUPLED_NUCLEOTIDE_EXCISION_REPAIR_TC_NER",2.796105156,0.024149925,0.012548465,0.005223948,-0.220596276,-3.385227689,"Up"]
[2080,"WP_KIT_RECEPTOR_SIGNALING_PATHWAY",2.795738661,0.021181505,0.012548874,0.005229851,-0.181998319,-3.386243872,"Up"]
[2079,"WP_NUCLEOTIDE_GPCRS",2.795569839,0.021022685,0.012548874,0.005232572,0.240931566,-3.386711921,"Up"]
[2078,"REACTOME_DCC_MEDIATED_ATTRACTIVE_SIGNALING",2.793038948,0.037917821,0.012630609,0.005273518,-0.226734619,-3.39372532,"Up"]
[2077,"WP_IL5_SIGNALING_PATHWAY",2.788886462,0.028623376,0.012775611,0.005341326,-0.22430238,-3.4052187,"Up"]
[2076,"WP_NCRNAS_INVOLVED_IN_STAT3_SIGNALING_IN_HEPATOCELLULAR_CARCINOMA",2.788703763,0.042437402,0.012775611,0.005344327,-0.115922273,-3.40572399,"Up"]
[2075,"REACTOME_EPIGENETIC_REGULATION_OF_GENE_EXPRESSION",2.786683213,0.022314856,0.012844862,0.005377623,-0.210918433,-3.411310034,"Up"]
[2074,"BIOCARTA_KREB_PATHWAY",2.784619226,0.043274104,0.012916172,0.005411828,-0.326761333,-3.417012018,"Up"]
[2073,"BIOCARTA_IL6_PATHWAY",2.784264331,0.036488768,0.01291987,0.005417729,-0.201594454,-3.417992032,"Up"]
[2072,"REACTOME_TYSND1_CLEAVES_PEROXISOMAL_PROTEINS",2.782330525,0.041752959,0.012975951,0.005449987,-0.309438731,-3.423329899,"Up"]
[2071,"WP_ERK_PATHWAY_IN_HUNTINGTONS_DISEASE",2.781643176,0.029666786,0.01299293,0.005461494,-0.216697464,-3.425226295,"Up"]
[2070,"REACTOME_THYROXINE_BIOSYNTHESIS",2.774511973,0.031410794,0.013269418,0.005582184,0.227949973,-3.444873875,"Up"]
[2069,"WP_TRYPTOPHAN_CATABOLISM_LEADING_TO_NAD_PRODUCTION",2.771868409,0.027228928,0.013366514,0.005627532,0.026510968,-3.452144594,"Up"]
[2068,"REACTOME_TRANSLESION_SYNTHESIS_BY_POLK",2.762321028,0.042381757,0.013751129,0.005794093,-0.224787579,-3.478345964,"Up"]
[2067,"BIOCARTA_TNFR1_PATHWAY",2.761766254,0.026688304,0.013763418,0.005803907,-0.167593846,-3.479865702,"Up"]
[2066,"REACTOME_RUNX1_REGULATES_TRANSCRIPTION_OF_GENES_INVOLVED_IN_BCR_SIGNALING",2.746543454,0.053116966,0.014370137,0.006079115,-0.290646669,-3.521448605,"Up"]
[2065,"BIOCARTA_NGF_PATHWAY",2.74579146,0.032560995,0.014391525,0.00609301,-0.278138358,-3.523496855,"Up"]
[2064,"REACTOME_AKT_PHOSPHORYLATES_TARGETS_IN_THE_NUCLEUS",2.741029279,0.038144841,0.014566174,0.006181671,-0.318563366,-3.536454977,"Up"]
[2063,"REACTOME_HDL_CLEARANCE",2.740757789,0.061877933,0.014566606,0.00618676,0.039717374,-3.53719304,"Up"]
[2062,"KEGG_RNA_POLYMERASE",2.735924314,0.030974616,0.014758028,0.006278003,-0.1713767,-3.550321044,"Up"]
[2061,"WP_IL2_SIGNALING_PATHWAY",2.734470825,0.025570958,0.014811356,0.006305676,-0.217668714,-3.55426431,"Up"]
[2060,"REACTOME_TNF_SIGNALING",2.725798392,0.024259248,0.01514469,0.006473093,-0.177037276,-3.577749108,"Up"]
[2059,"REACTOME_DUAL_INCISION_IN_TC_NER",2.723421216,0.024677522,0.015229676,0.006519676,-0.218771336,-3.584173535,"Up"]
[2058,"REACTOME_SOS_MEDIATED_SIGNALLING",2.717275128,0.042588325,0.015497156,0.006641517,-0.341891052,-3.60075784,"Up"]
[2057,"KEGG_WNT_SIGNALING_PATHWAY",2.717119898,0.016431754,0.015497156,0.006644621,-0.163481929,-3.601176222,"Up"]
[2056,"REACTOME_CALCITONIN_LIKE_LIGAND_RECEPTORS",2.711017312,0.036327619,0.015759394,0.006767675,-0.076086582,-3.617605425,"Up"]
[2055,"REACTOME_COPII_MEDIATED_VESICLE_TRANSPORT",2.706675162,0.02137752,0.015953663,0.006856475,-0.224830498,-3.629272913,"Up"]
[2054,"REACTOME_SIGNALING_BY_NTRK2_TRKB",2.69475408,0.026148006,0.016507643,0.007105681,-0.186227787,-3.661209793,"Up"]
[2053,"REACTOME_TBC_RABGAPS",2.691021956,0.024239763,0.016672338,0.007185356,-0.197145732,-3.671179494,"Up"]
[2052,"WP_ESTROGEN_SIGNALING_PATHWAY",2.690907848,0.030075605,0.016672338,0.007187805,-0.246687254,-3.671484099,"Up"]
[2051,"REACTOME_SIGNALING_BY_NOTCH",2.686625443,0.023133326,0.01687357,0.007280244,-0.166200201,-3.6829064,"Up"]
[2050,"REACTOME_METABOLISM_OF_NUCLEOTIDES",2.679970368,0.017857438,0.017198009,0.007426018,-0.13839424,-3.700621408,"Up"]
[2049,"REACTOME_TRYPTOPHAN_CATABOLISM",2.677539124,0.031059034,0.017309345,0.007479923,0.05154869,-3.707082208,"Up"]
[2048,"PID_INTEGRIN3_PATHWAY",2.677161647,0.037075529,0.017312337,0.007488323,-0.152903298,-3.708084797,"Up"]
[2047,"REACTOME_FGFR3_LIGAND_BINDING_AND_ACTIVATION",2.676957175,0.023198696,0.017312337,0.007492877,0.229992905,-3.708627821,"Up"]
[2046,"REACTOME_ACTIVATION_OF_RAC1_DOWNSTREAM_OF_NMDARS",2.671613817,0.045421313,0.017559402,0.00761277,-0.198285662,-3.72280378,"Up"]
[2045,"KEGG_NEUROACTIVE_LIGAND_RECEPTOR_INTERACTION",2.670547927,0.012763733,0.017590325,0.007636891,0.289407654,-3.72562823,"Up"]
[2044,"REACTOME_CHYLOMICRON_REMODELING",2.66683568,0.047943165,0.017771271,0.007721435,-0.003144816,-3.735456396,"Up"]
[2043,"WP_NONSMALL_CELL_LUNG_CANCER",2.663270025,0.017718401,0.017946074,0.007803429,-0.221753356,-3.744883684,"Up"]
[2042,"REACTOME_G_ALPHA_Q_SIGNALLING_EVENTS",2.657234881,0.009453569,0.018241076,0.007943992,0.04043562,-3.760811564,"Up"]
[2041,"REACTOME_SIGNALING_BY_FGFR",2.647287681,0.021119847,0.018740958,0.008180627,-0.193159622,-3.786985814,"Up"]
[2040,"BIOCARTA_RAS_PATHWAY",2.645478457,0.034102377,0.018826571,0.008224339,-0.212240095,-3.791735984,"Up"]
[2039,"REACTOME_STAT5_ACTIVATION_DOWNSTREAM_OF_FLT3_ITD_MUTANTS",2.645197765,0.036064442,0.018827622,0.00823114,-0.267574558,-3.792472662,"Up"]
[2038,"REACTOME_NEGATIVE_REGULATION_OF_ACTIVITY_OF_TFAP2_AP_2_FAMILY_TRANSCRIPTION_FACTORS",2.644611534,0.038808454,0.018845628,0.008245359,-0.046441808,-3.794010976,"Up"]
[2037,"WP_NETRINUNC5B_SIGNALING_PATHWAY",2.635736792,0.020995731,0.019328921,0.00846332,-0.180338754,-3.817257601,"Up"]
[2036,"REACTOME_SIGNALING_BY_FGFR1",2.631125991,0.021627513,0.019577106,0.008578584,-0.192825188,-3.829304579,"Up"]
[2035,"REACTOME_COMPLEX_I_BIOGENESIS",2.627612591,0.034254547,0.019749328,0.008667354,-0.172844689,-3.838470239,"Up"]
[2034,"PID_FCER1_PATHWAY",2.617840397,0.01781744,0.020290665,0.008918598,-0.148570456,-3.863899726,"Up"]
[2033,"WP_CHOLESTEROL_BIOSYNTHESIS_PATHWAY",2.61603933,0.03249898,0.020381998,0.008965608,-0.269395508,-3.868576248,"Up"]
[2032,"REACTOME_PD_1_SIGNALING",2.614852655,0.020406759,0.020437038,0.008996702,0.207043093,-3.871655739,"Up"]
[2031,"REACTOME_DISORDERS_OF_TRANSMEMBRANE_TRANSPORTERS",2.610479962,0.022142078,0.020651804,0.009112113,-0.136882845,-3.882991153,"Up"]
[2030,"REACTOME_DEATH_RECEPTOR_SIGNALLING",2.605949219,0.015269335,0.020882316,0.009233089,-0.144813092,-3.894716414,"Up"]
[2029,"REACTOME_FORMATION_OF_RNA_POL_II_ELONGATION_COMPLEX",2.605881012,0.022555186,0.020882316,0.009234921,-0.254886099,-3.894892773,"Up"]
[2028,"REACTOME_B_WICH_COMPLEX_POSITIVELY_REGULATES_RRNA_EXPRESSION",2.605305142,0.032565273,0.020901404,0.009250402,-0.160386965,-3.896381601,"Up"]
[2027,"REACTOME_SIGNALING_BY_ERBB2_ECD_MUTANTS",2.595407767,0.032569555,0.021494489,0.009520126,-0.256254391,-3.921918722,"Up"]
[2026,"REACTOME_REGULATION_OF_TLR_BY_ENDOGENOUS_LIGAND",2.594769138,0.030621027,0.021517959,0.009537768,-0.015851067,-3.923563194,"Up"]
[2025,"PID_LYSOPHOSPHOLIPID_PATHWAY",2.591399994,0.022808953,0.021712536,0.009631327,-0.153386091,-3.932232093,"Up"]
[2024,"REACTOME_FORMATION_OF_XYLULOSE_5_PHOSPHATE",2.585596743,0.054105914,0.022046684,0.009794401,-0.227141121,-3.94713779,"Up"]
[2023,"REACTOME_PHOSPHOLIPASE_C_MEDIATED_CASCADE_FGFR2",2.585245864,0.02675693,0.022052336,0.009804339,0.076188552,-3.94803796,"Up"]
[2022,"REACTOME_RUNX1_INTERACTS_WITH_CO_FACTORS_WHOSE_PRECISE_EFFECT_ON_RUNX1_TARGETS_IS_NOT_KNOWN",2.579985992,0.025619136,0.022372914,0.009954402,-0.296686997,-3.961517499,"Up"]
[2021,"REACTOME_CHONDROITIN_SULFATE_BIOSYNTHESIS",2.579215974,0.028527193,0.022405712,0.009976541,-0.073108146,-3.963488544,"Up"]
[2020,"WP_MIRNAS_INVOLVEMENT_IN_THE_IMMUNE_RESPONSE_IN_SEPSIS",2.575438479,0.018996141,0.022616847,0.010085788,-0.163402161,-3.97314949,"Up"]
[2019,"REACTOME_ASSOCIATION_OF_TRIC_CCT_WITH_TARGET_PROTEINS_DURING_BIOSYNTHESIS",2.564560852,0.02452803,0.023247902,0.010406353,-0.235031897,-4.000890481,"Up"]
[2018,"WP_ENDOMETRIAL_CANCER",2.55214787,0.020509995,0.024035578,0.010783223,-0.215969991,-4.032404597,"Up"]
[2017,"WP_SUPRESSION_OF_HMGB1_MEDIATED_INFLAMMATION_BY_THBD",2.551055734,0.039858247,0.024092679,0.010816956,-0.179409426,-4.035170047,"Up"]
[2016,"PID_ECADHERIN_KERATINOCYTE_PATHWAY",2.547402888,0.033285378,0.024327245,0.010930463,-0.233664912,-4.044411051,"Up"]
[2015,"REACTOME_NEGATIVE_REGULATION_OF_MET_ACTIVITY",2.543959332,0.031560347,0.024530776,0.011038436,-0.239744199,-4.053110548,"Up"]
[2014,"WP_MITOCHONDRIAL_COMPLEX_I_ASSEMBLY_MODEL_OXPHOS_SYSTEM",2.537464548,0.032662308,0.024970387,0.011244664,-0.176649472,-4.069486589,"Up"]
[2013,"REACTOME_RUNX1_REGULATES_TRANSCRIPTION_OF_GENES_INVOLVED_IN_INTERLEUKIN_SIGNALING",2.534764277,0.050628888,0.025144209,0.011331408,-0.321579643,-4.076282854,"Up"]
[2012,"REACTOME_ELASTIC_FIBRE_FORMATION",2.525161142,0.031246109,0.025781678,0.011644739,-0.165851036,-4.100394579,"Up"]
[2011,"PID_PTP1B_PATHWAY",2.52396208,0.019612192,0.025848633,0.011684398,-0.158289463,-4.103398823,"Up"]
[2010,"REACTOME_RIPK1_MEDIATED_REGULATED_NECROSIS",2.522230813,0.031105564,0.025919414,0.01174187,-0.158234698,-4.107734,"Up"]
[2009,"BIOCARTA_LDL_PATHWAY",2.520842147,0.039859483,0.026002242,0.01178815,-0.275392216,-4.111209154,"Up"]
[2008,"REACTOME_SHC1_EVENTS_IN_EGFR_SIGNALING",2.52023158,0.029648843,0.026027902,0.01180855,-0.192296817,-4.112736502,"Up"]
[2007,"BIOCARTA_RHODOPSIN_PATHWAY",2.518566021,0.011828574,0.026083496,0.011864357,0.598358299,-4.116901074,"Up"]
[2006,"REACTOME_TRNA_MODIFICATION_IN_THE_MITOCHONDRION",2.517877996,0.040079519,0.026093654,0.011887479,-0.170475136,-4.118620615,"Up"]
[2005,"WP_ACTIVATION_OF_NLRP3_INFLAMMASOME_BY_SARSCOV2",2.517769971,0.031824981,0.026093654,0.011891113,-0.196775902,-4.118890553,"Up"]
[2004,"REACTOME_NTRK2_ACTIVATES_RAC1",2.51458976,0.059531881,0.026309936,0.011998536,-0.193316964,-4.126832274,"Up"]
[2003,"REACTOME_COOPERATION_OF_PDCL_PHLP1_AND_TRIC_CCT_IN_G_PROTEIN_BETA_FOLDING",2.506389189,0.032726112,0.02688636,0.012279523,-0.16295503,-4.147264983,"Up"]
[2002,"REACTOME_GLYCOGEN_SYNTHESIS",2.499748711,0.040532644,0.027333399,0.012511313,-0.121998271,-4.163761952,"Up"]
[2001,"PID_ATR_PATHWAY",2.496776963,0.018846264,0.027522247,0.012616294,-0.093505431,-4.171130593,"Up"]
[2000,"WP_NONALCOHOLIC_FATTY_LIVER_DISEASE",2.490846996,0.025712304,0.027902321,0.012828113,-0.171104087,-4.185808308,"Up"]
[1999,"REACTOME_MEIOTIC_SYNAPSIS",2.490305655,0.021825055,0.027924262,0.012847606,-0.114249255,-4.187146494,"Up"]
[1998,"REACTOME_MHC_CLASS_II_ANTIGEN_PRESENTATION",2.482482656,0.019165696,0.028480367,0.013132241,-0.137683721,-4.206452574,"Up"]
[1997,"WP_NEURODEGENERATION_WITH_BRAIN_IRON_ACCUMULATION_NBIA_SUBTYPES_PATHWAY",2.482210793,0.020988205,0.028481231,0.013142232,-0.234198329,-4.20712241,"Up"]
[1996,"REACTOME_RNA_POLYMERASE_III_TRANSCRIPTION_INITIATION_FROM_TYPE_3_PROMOTER",2.479936596,0.025345725,0.028642022,0.013226074,-0.206559397,-4.212722881,"Up"]
[1995,"REACTOME_TNFR1_INDUCED_PROAPOPTOTIC_SIGNALING",2.472501097,0.028278546,0.029221512,0.013503508,-0.157744102,-4.230998053,"Up"]
[1994,"WP_GLYCOGEN_SYNTHESIS_AND_DEGRADATION",2.464222011,0.023555847,0.029881292,0.013818462,-0.200609216,-4.25128246,"Up"]
[1993,"BIOCARTA_PCAF_PATHWAY",2.455170549,0.03350539,0.030588971,0.014170211,-0.260715275,-4.273381892,"Up"]
[1992,"REACTOME_ANTI_INFLAMMATORY_RESPONSE_FAVOURING_LEISHMANIA_PARASITE_INFECTION",2.455007141,0.011354829,0.030588971,0.014176633,-0.012079242,-4.273780116,"Up"]
[1991,"REACTOME_SIGNALING_BY_RECEPTOR_TYROSINE_KINASES",2.4543633,0.01555542,0.03062137,0.014201962,-0.152760369,-4.275348891,"Up"]
[1990,"WP_FOCAL_ADHESION_PI3KAKTMTORSIGNALING_PATHWAY",2.45398175,0.015637087,0.030621821,0.014216992,-0.134630682,-4.276278378,"Up"]
[1989,"WP_DNA_IRDOUBLE_STRAND_BREAKS_AND_CELLULAR_RESPONSE_VIA_ATM",2.4538344,0.015722673,0.030621821,0.014222799,-0.210357351,-4.276637297,"Up"]
[1988,"REACTOME_SYNTHESIS_OF_DIPHTHAMIDE_EEF2",2.452547304,0.034314926,0.03070897,0.01427362,-0.113269935,-4.279771525,"Up"]
[1987,"WP_KREBS_CYCLE_DISORDERS",2.448766542,0.03922784,0.031009669,0.014423831,-0.275047868,-4.288968665,"Up"]
[1986,"WP_KETOGENESIS_AND_KETOLYSIS",2.443117466,0.034508801,0.031474987,0.01465087,-0.144497205,-4.302684422,"Up"]
[1985,"REACTOME_NUCLEAR_SIGNALING_BY_ERBB4",2.430867731,0.019635486,0.032508945,0.015154052,-0.128616587,-4.332318201,"Up"]
[1984,"REACTOME_TRANSCRIPTIONAL_REGULATION_BY_TP53",2.427977736,0.016053328,0.03272104,0.015274962,-0.177361988,-4.339287911,"Up"]
[1983,"REACTOME_DEFECTIVE_B4GALT7_CAUSES_EDS_PROGEROID_TYPE",2.421698724,0.027085445,0.033218156,0.015540592,-0.1253676,-4.354402407,"Up"]
[1982,"BIOCARTA_CDMAC_PATHWAY",2.419446682,0.028563576,0.033399863,0.015636851,-0.221562619,-4.359813923,"Up"]
[1981,"PID_GMCSF_PATHWAY",2.418214027,0.021767163,0.033469972,0.01568976,-0.231160893,-4.362773796,"Up"]
[1980,"REACTOME_TCF_DEPENDENT_SIGNALING_IN_RESPONSE_TO_WNT",2.413880147,0.021298694,0.033791338,0.015877035,-0.170831147,-4.373168486,"Up"]
[1979,"BIOCARTA_ALK_PATHWAY",2.413508252,0.023561612,0.033801504,0.015893196,-0.265510798,-4.374059603,"Up"]
[1978,"REACTOME_INTERLEUKIN_23_SIGNALING",2.40852711,0.042923588,0.034197513,0.016111063,-0.08614685,-4.385982014,"Up"]
[1977,"WP_METHYLATION_PATHWAYS",2.408461477,0.035885004,0.034197513,0.016113951,-0.168165708,-4.386138945,"Up"]
[1976,"SIG_BCR_SIGNALING_PATHWAY",2.405779297,0.020298796,0.034424216,0.016232369,-0.202364317,-4.392548454,"Up"]
[1975,"BIOCARTA_CXCR4_PATHWAY",2.40486048,0.026455114,0.034485984,0.01627311,-0.275162667,-4.394742485,"Up"]
[1974,"PID_ENDOTHELIN_PATHWAY",2.396081352,0.020710198,0.035194984,0.016666941,-0.121274136,-4.41566405,"Up"]
[1973,"REACTOME_RESPIRATORY_ELECTRON_TRANSPORT",2.394265463,0.030385699,0.035344055,0.016749439,-0.171185537,-4.419982007,"Up"]
[1972,"REACTOME_APEX1_INDEPENDENT_RESOLUTION_OF_AP_SITES_VIA_THE_SINGLE_NUCLEOTIDE_REPLACEMENT_PATHWAY",2.393122848,0.030521862,0.035403657,0.016801533,-0.150589664,-4.422697334,"Up"]
[1971,"KEGG_ADHERENS_JUNCTION",2.391448843,0.023968158,0.035514609,0.016878112,-0.202967646,-4.42667314,"Up"]
[1970,"REACTOME_EGFR_TRANSACTIVATION_BY_GASTRIN",2.377595421,0.038162786,0.036716914,0.0175237,-0.258950124,-4.459469232,"Up"]
[1969,"REACTOME_ABORTIVE_ELONGATION_OF_HIV_1_TRANSCRIPT_IN_THE_ABSENCE_OF_TAT",2.375756014,0.029042193,0.036873867,0.017611028,-0.281363055,-4.463809534,"Up"]
[1968,"REACTOME_EPHA_MEDIATED_GROWTH_CONE_COLLAPSE",2.365976366,0.030993389,0.037779571,0.018081768,-0.155031634,-4.486829713,"Up"]
[1967,"WP_HOSTPATHOGEN_INTERACTION_OF_HUMAN_CORONAVIRUSES_APOPTOSIS",2.361266427,0.023086791,0.038234516,0.018312389,-0.151189278,-4.497882695,"Up"]
[1966,"WP_NUCLEAR_RECEPTORS_METAPATHWAY",2.358456813,0.011211567,0.038460382,0.018451184,-0.109343764,-4.50446569,"Up"]
[1965,"KEGG_BIOSYNTHESIS_OF_UNSATURATED_FATTY_ACIDS",2.351297972,0.023585439,0.0391338,0.018809004,-0.096844982,-4.521203808,"Up"]
[1964,"REACTOME_RETINOID_CYCLE_DISEASE_EVENTS",2.34882607,0.017292571,0.039366196,0.01893396,0.312865548,-4.526971624,"Up"]
[1963,"REACTOME_TRANSCRIPTIONAL_REGULATION_BY_RUNX2",2.345938871,0.025407955,0.039643795,0.019080829,-0.170612337,-4.533700837,"Up"]
[1962,"WP_KALLMANN_SYNDROME",2.340801834,0.028876233,0.040163742,0.019344611,-0.22490813,-4.545653413,"Up"]
[1961,"WP_ID_SIGNALING_PATHWAY",2.339259415,0.03050998,0.040301287,0.019424433,-0.195211149,-4.549237145,"Up"]
[1960,"KEGG_DNA_REPLICATION",2.33898877,0.020827387,0.040302244,0.019438469,-0.126453223,-4.549865732,"Up"]
[1959,"REACTOME_DEFECTS_IN_BIOTIN_BTN_METABOLISM",2.338571165,0.025464244,0.040319027,0.019460143,-0.081865646,-4.550835499,"Up"]
[1958,"REACTOME_REMOVAL_OF_AMINOTERMINAL_PROPEPTIDES_FROM_GAMMA_CARBOXYLATED_PROTEINS",2.338049668,0.040186939,0.040347012,0.01948724,-0.070976881,-4.552046286,"Up"]
[1957,"REACTOME_TRANSCRIPTIONAL_REGULATION_BY_THE_AP_2_TFAP2_FAMILY_OF_TRANSCRIPTION_FACTORS",2.332536002,0.022609204,0.040915819,0.01977575,-0.1063374,-4.564831216,"Up"]
[1956,"REACTOME_WNT_LIGAND_BIOGENESIS_AND_TRAFFICKING",2.330874297,0.021045992,0.041040029,0.019863429,-0.01719179,-4.568678443,"Up"]
[1955,"KEGG_INSULIN_SIGNALING_PATHWAY",2.327912482,0.01335362,0.041335895,0.020020551,-0.195145305,-4.575528963,"Up"]
[1954,"REACTOME_OVARIAN_TUMOR_DOMAIN_PROTEASES",2.316679592,0.02281711,0.042499461,0.020626357,-0.175905482,-4.601431326,"Up"]
[1953,"BIOCARTA_PTEN_PATHWAY",2.316666837,0.030045992,0.042499461,0.020627054,-0.295482646,-4.601460669,"Up"]
[1952,"REACTOME_GLUCAGON_SIGNALING_IN_METABOLIC_REGULATION",2.314459946,0.024315167,0.042689283,0.02074794,-0.116372332,-4.606534953,"Up"]
[1951,"REACTOME_EGFR_DOWNREGULATION",2.312040705,0.024717461,0.042933649,0.020881169,-0.20117534,-4.61209197,"Up"]
[1950,"PID_CD8_TCR_PATHWAY",2.309684895,0.015369995,0.043171972,0.02101162,-0.048529296,-4.617497728,"Up"]
[1949,"BIOCARTA_MHC_PATHWAY",2.304835275,0.038989406,0.043698103,0.021282404,-0.18365754,-4.628608658,"Up"]
[1948,"REACTOME_PREVENTION_OF_PHAGOSOMAL_LYSOSOMAL_FUSION",2.303181044,0.050916323,0.043858845,0.021375463,-0.185248659,-4.632393344,"Up"]
[1947,"BIOCARTA_EIF4_PATHWAY",2.302684378,0.027777883,0.043885986,0.021403472,-0.279637723,-4.633529129,"Up"]
[1946,"KEGG_LEUKOCYTE_TRANSENDOTHELIAL_MIGRATION",2.29331359,0.018319568,0.044875224,0.021937958,-0.077830347,-4.654912777,"Up"]
[1945,"REACTOME_NR1H3_NR1H2_REGULATE_GENE_EXPRESSION_LINKED_TO_CHOLESTEROL_TRANSPORT_AND_EFFLUX",2.293167395,0.022861234,0.044875224,0.021946388,-0.241958854,-4.655245698,"Up"]
[1944,"KEGG_RNA_DEGRADATION",2.284330654,0.019111252,0.045864709,0.022461194,-0.221782964,-4.675329957,"Up"]
[1943,"REACTOME_CARGO_CONCENTRATION_IN_THE_ER",2.281837899,0.022811493,0.046101683,0.022608303,-0.169897399,-4.680981575,"Up"]
[1942,"WP_PHOTODYNAMIC_THERAPYINDUCED_NFE2L2_NRF2_SURVIVAL_SIGNALING",2.276437247,0.025526274,0.046661317,0.022929896,-0.120416112,-4.693204981,"Up"]
[1941,"REACTOME_MET_RECEPTOR_RECYCLING",2.276081948,0.030511433,0.046672664,0.022951192,-0.196418606,-4.694008126,"Up"]
[1940,"REACTOME_STING_MEDIATED_INDUCTION_OF_HOST_IMMUNE_RESPONSES",2.273559218,0.030898414,0.046949001,0.023102893,-0.194988308,-4.699707116,"Up"]
[1939,"REACTOME_CONSTITUTIVE_SIGNALING_BY_AKT1_E17K_IN_CANCER",2.271862252,0.022937483,0.047125113,0.023205428,-0.302114446,-4.703537122,"Up"]
[1938,"WP_OXIDATIVE_PHOSPHORYLATION",2.269449654,0.03449131,0.047390118,0.023351883,-0.167079674,-4.708977392,"Up"]
[1937,"WP_B_CELL_RECEPTOR_SIGNALING_PATHWAY",2.267235957,0.013678092,0.047599191,0.02348697,-0.204749947,-4.713964096,"Up"]
[1936,"WP_BIOGENIC_AMINE_SYNTHESIS",2.264112176,0.033150151,0.047950314,0.023678748,0.224207099,-4.720992671,"Up"]
[1935,"REACTOME_VASOPRESSIN_REGULATES_RENAL_WATER_HOMEOSTASIS_VIA_AQUAPORINS",2.263888597,0.020753746,0.047950314,0.023692526,-0.11932935,-4.72149536,"Up"]
[1934,"REACTOME_NEGATIVE_REGULATORS_OF_DDX58_IFIH1_SIGNALING",2.263074323,0.026416582,0.048019257,0.023742765,-0.193399348,-4.723325732,"Up"]
[1933,"REACTOME_NONCANONICAL_ACTIVATION_OF_NOTCH3",2.262152614,0.033624503,0.048101729,0.023799744,-0.289073358,-4.725396811,"Up"]
[1932,"WP_TUMOR_SUPPRESSOR_ACTIVITY_OF_SMARCB1",2.258305109,0.020403447,0.048518982,0.024038876,-0.255218265,-4.734033089,"Up"]
[1931,"REACTOME_JNK_C_JUN_KINASES_PHOSPHORYLATION_AND_ACTIVATION_MEDIATED_BY_ACTIVATED_HUMAN_TAK1",2.25511613,0.028033572,0.048834122,0.024238656,-0.179828725,-4.741180128,"Up"]
[1930,"REACTOME_SIGNALING_BY_FGFR4_IN_DISEASE",2.254982438,0.031025681,0.048834122,0.024247063,-0.287675547,-4.741479534,"Up"]
[1929,"REACTOME_REGULATION_OF_GENE_EXPRESSION_BY_HYPOXIA_INDUCIBLE_FACTOR",2.254763986,0.036493348,0.048834122,0.024260805,-0.28346639,-4.741968726,"Up"]
[1928,"REACTOME_INHIBITION_OF_DNA_RECOMBINATION_AT_TELOMERE",2.253061179,0.02711754,0.049016972,0.024368155,-0.200712947,-4.745780296,"Up"]
[1927,"WP_DOPAMINERGIC_NEUROGENESIS",2.251410554,0.017362333,0.049165416,0.024472608,0.193253743,-4.749472329,"Up"]
[1926,"WP_NANOMATERIAL_INDUCED_APOPTOSIS",2.249256383,0.024414041,0.049402051,0.024609509,-0.174350108,-4.754286619,"Up"]
[1925,"WP_PROLACTIN_SIGNALING_PATHWAY",2.24367747,0.018537123,0.05005231,0.024967151,-0.199944427,-4.766733449,"Up"]
[1924,"REACTOME_SUMOYLATION",2.241576148,0.013887735,0.050290735,0.025103021,-0.213648784,-4.771413629,"Up"]
[1923,"PID_IL5_PATHWAY",2.237707088,0.027488433,0.050726822,0.025354868,-0.193195149,-4.780019604,"Up"]
[1922,"KEGG_PARKINSONS_DISEASE",2.229771185,0.030810375,0.051634844,0.025878292,-0.155948387,-4.797625206,"Up"]
[1921,"PID_AJDISS_2PATHWAY",2.22773788,0.022059594,0.051870557,0.026013897,-0.2059708,-4.802126029,"Up"]
[1920,"REACTOME_SIGNALING_BY_TGF_BETA_RECEPTOR_COMPLEX_IN_CANCER",2.225766395,0.034283207,0.052098907,0.026145965,-0.307284402,-4.806486109,"Up"]
[1919,"REACTOME_TRAFFICKING_AND_PROCESSING_OF_ENDOSOMAL_TLR",2.223888344,0.03515949,0.05231556,0.026272314,-0.17902125,-4.810635982,"Up"]
[1918,"REACTOME_ENDOSOMAL_SORTING_COMPLEX_REQUIRED_FOR_TRANSPORT_ESCRT",2.22093799,0.029605286,0.052607082,0.026471869,-0.209520691,-4.817148253,"Up"]
[1917,"WP_ELECTRON_TRANSPORT_CHAIN_OXPHOS_SYSTEM_IN_MITOCHONDRIA",2.218400259,0.033190313,0.052879484,0.026644563,-0.170368886,-4.822742868,"Up"]
[1916,"REACTOME_CITRIC_ACID_CYCLE_TCA_CYCLE",2.215360299,0.023815252,0.053256988,0.026852715,-0.304665533,-4.829436306,"Up"]
[1915,"REACTOME_MRNA_DECAY_BY_5_TO_3_EXORIBONUCLEASE",2.213092482,0.028602792,0.053531012,0.027008911,-0.19571224,-4.83442368,"Up"]
[1914,"PID_REG_GR_PATHWAY",2.211663423,0.020001616,0.053691046,0.027107739,-0.237585369,-4.837563849,"Up"]
[1913,"BIOCARTA_TRKA_PATHWAY",2.209149052,0.025394409,0.053964954,0.027282383,-0.276571944,-4.843083952,"Up"]
[1912,"WP_OXIDATIVE_STRESS_RESPONSE",2.204461497,0.021572552,0.054541434,0.027610568,-0.099515407,-4.853358428,"Up"]
[1911,"BIOCARTA_SHH_PATHWAY",2.199891312,0.026680977,0.055106632,0.02793381,-0.205709101,-4.86335474,"Up"]
[1910,"REACTOME_RESPIRATORY_ELECTRON_TRANSPORT_ATP_SYNTHESIS_BY_CHEMIOSMOTIC_COUPLING_AND_HEAT_PRODUCTION_BY_UNCOUPLING_PROTEINS",2.193032492,0.029248639,0.056001308,0.028425049,-0.157695587,-4.878318224,"Up"]
[1909,"REACTOME_REGULATION_OF_TP53_ACTIVITY_THROUGH_ACETYLATION",2.187843088,0.022624307,0.056630538,0.028801655,-0.297536887,-4.889608748,"Up"]
[1908,"WP_OVERVIEW_OF_PROINFLAMMATORY_AND_PROFIBROTIC_MEDIATORS",2.182769504,0.010873386,0.057286784,0.029174004,0.247908002,-4.900621552,"Up"]
[1907,"REACTOME_CA_DEPENDENT_EVENTS",2.181083532,0.01902342,0.057493519,0.029298651,-0.170834365,-4.90427552,"Up"]
[1906,"REACTOME_TRANSLATION_OF_SARS_COV_1_STRUCTURAL_PROTEINS",2.173383766,0.026121165,0.058544675,0.029873757,-0.177837842,-4.920927326,"Up"]
[1905,"REACTOME_SIGNALING_BY_FGFR_IN_DISEASE",2.165330321,0.015708442,0.059615078,0.030485645,-0.21808101,-4.938281315,"Up"]
[1904,"REACTOME_REGULATION_OF_TNFR1_SIGNALING",2.165139523,0.022427334,0.059615078,0.030500271,-0.165479521,-4.938691678,"Up"]
[1903,"WP_IL6_SIGNALING_PATHWAY",2.156006573,0.021056582,0.060917158,0.031207476,-0.218634912,-4.958292545,"Up"]
[1902,"REACTOME_SUMOYLATION_OF_INTRACELLULAR_RECEPTORS",2.151464807,0.020351216,0.061452221,0.031564378,-0.160611019,-4.968009251,"Up"]
[1901,"REACTOME_DAP12_INTERACTIONS",2.147851055,0.023487544,0.061969317,0.031850851,-0.146633844,-4.975725987,"Up"]
[1900,"WP_PHASE_I_BIOTRANSFORMATIONS_NON_P450",2.145135672,0.033212971,0.062350116,0.032067574,-0.065757483,-4.98151587,"Up"]
[1899,"BIOCARTA_NOTCH_PATHWAY",2.143965303,0.036193264,0.06249157,0.032161374,-0.280543615,-4.984009144,"Up"]
[1898,"REACTOME_COMPLEMENT_CASCADE",2.13401136,0.026064881,0.063934714,0.032968692,0.068097519,-5.005159608,"Up"]
[1897,"REACTOME_PTK6_REGULATES_RTKS_AND_THEIR_EFFECTORS_AKT1_AND_DOK1",2.132898858,0.049302275,0.064069918,0.033059991,-0.19415053,-5.007517402,"Up"]
[1896,"REACTOME_SHC_RELATED_EVENTS_TRIGGERED_BY_IGF1R",2.132138474,0.033516785,0.064149222,0.033122518,-0.296936265,-5.009128228,"Up"]
[1895,"REACTOME_TOXICITY_OF_BOTULINUM_TOXIN_TYPE_D_BOTD",2.129208609,0.043456148,0.064575538,0.033364391,0.180728677,-5.015329616,"Up"]
[1894,"PID_BCR_5PATHWAY",2.126103545,0.016808874,0.064990125,0.033622375,-0.175037466,-5.02189257,"Up"]
[1893,"BIOCARTA_EGF_PATHWAY",2.123421627,0.022345935,0.065316291,0.033846576,-0.217116174,-5.027553477,"Up"]
[1892,"BIOCARTA_PAR1_PATHWAY",2.123295939,0.025556832,0.065316291,0.033857114,-0.234980234,-5.027818601,"Up"]
[1891,"REACTOME_TRANSPORT_OF_FATTY_ACIDS",2.120501285,0.033234096,0.06572703,0.034092161,{"v":1.85e-05,"d":"1.85E-05"},-5.033709555,"Up"]
[1890,"KEGG_TGF_BETA_SIGNALING_PATHWAY",2.120169934,0.016212971,0.065736695,0.034120122,-0.215977285,-5.034407509,"Up"]
[1889,"SIG_CD40PATHWAYMAP",2.119917271,0.016166905,0.065736695,0.034141456,-0.18818289,-5.034939645,"Up"]
[1888,"REACTOME_SIGNAL_ATTENUATION",2.119584802,0.030498571,0.065737142,0.034169546,-0.355246749,-5.035639762,"Up"]
[1887,"REACTOME_MET_ACTIVATES_PTPN11",2.11939051,0.038081882,0.065737142,0.034185971,-0.21365839,-5.036048854,"Up"]
[1886,"WP_MITOCHONDRIAL_COMPLEX_III_ASSEMBLY",2.116383868,0.032082022,0.066184684,0.034441003,-0.213245385,-5.04237474,"Up"]
[1885,"WP_PHOSPHOINOSITIDES_METABOLISM",2.114520867,0.014881572,0.066446917,0.034599843,-0.194121265,-5.046289953,"Up"]
[1884,"REACTOME_DAG_AND_IP3_SIGNALING",2.112957955,0.017400024,0.066660633,0.03473358,-0.188169034,-5.049571864,"Up"]
[1883,"REACTOME_SIGNALING_BY_INTERLEUKINS",2.111594398,0.013924395,0.066712758,0.034850619,-0.111154049,-5.052433182,"Up"]
[1882,"REACTOME_TRAF6_MEDIATED_NF_KB_ACTIVATION",2.110706598,0.019469534,0.066815897,0.034927003,-0.135597104,-5.054295174,"Up"]
[1881,"REACTOME_PTK6_EXPRESSION",2.110148711,0.044020192,0.066820338,0.034975075,-0.211223274,-5.055464836,"Up"]
[1880,"SA_MMP_CYTOKINE_CONNECTION",2.109969379,0.021577341,0.066820338,0.03499054,0.118134963,-5.055840757,"Up"]
[1879,"REACTOME_MET_ACTIVATES_RAP1_AND_RAC1",2.109896315,0.032653758,0.066820338,0.034996843,-0.220679005,-5.055993907,"Up"]
[1878,"WP_THERMOGENESIS",2.108889838,0.014137245,0.066922933,0.035083759,-0.19695505,-5.058103052,"Up"]
[1877,"WP_INCLUSION_BODY_MYOSITIS",2.108752217,0.027661002,0.066922933,0.035095657,-0.250638067,-5.058391367,"Up"]
[1876,"REACTOME_IKK_COMPLEX_RECRUITMENT_MEDIATED_BY_RIP1",2.107817014,0.03165693,0.066991242,0.035176607,-0.152338175,-5.060350129,"Up"]
[1875,"REACTOME_FLT3_SIGNALING_BY_CBL_MUTANTS",2.105227671,0.05359675,0.067376448,0.035401569,-0.154818163,-5.065768932,"Up"]
[1874,"REACTOME_CYTOKINE_SIGNALING_IN_IMMUNE_SYSTEM",2.097750188,0.012220371,0.06849428,0.036058121,-0.12555932,-5.081380088,"Up"]
[1873,"REACTOME_PURINE_CATABOLISM",2.096634788,0.022393031,0.068638082,0.036156942,-0.121991273,-5.083704031,"Up"]
[1872,"REACTOME_TP53_REGULATES_TRANSCRIPTION_OF_CELL_CYCLE_GENES",2.094373108,0.017325756,0.068938692,0.03635803,-0.210683058,-5.08841248,"Up"]
[1871,"REACTOME_REGULATION_OF_FZD_BY_UBIQUITINATION",2.094331536,0.027542401,0.068938692,0.036361735,-0.062136164,-5.088498979,"Up"]
[1870,"REACTOME_CREB1_PHOSPHORYLATION_THROUGH_THE_ACTIVATION_OF_CAMKII_CAMKK_CAMKIV_CASCASDE",2.092969083,0.029755556,0.069125108,0.036483343,-0.122199281,-5.091332887,"Up"]
[1869,"BIOCARTA_PLCE_PATHWAY",2.090988111,0.029924573,0.069416991,0.036660775,-0.158276446,-5.095450041,"Up"]
[1868,"WP_NEURAL_CREST_CELL_MIGRATION_IN_CANCER",2.088366316,0.022091048,0.069791455,0.036896736,-0.132558789,-5.100893085,"Up"]
[1867,"BIOCARTA_TID_PATHWAY",2.088268636,0.021997294,0.069791455,0.036905552,-0.152760645,-5.101095743,"Up"]
[1866,"BIOCARTA_IGF1_PATHWAY",2.086029482,0.024906398,0.070129897,0.03710814,-0.281655986,-5.105738797,"Up"]
[1865,"REACTOME_GAB1_SIGNALOSOME",2.085224912,0.021314615,0.070223206,0.037181165,-0.133306132,-5.107405921,"Up"]
[1864,"REACTOME_APOPTOTIC_FACTOR_MEDIATED_RESPONSE",2.08356454,0.024976268,0.070463735,0.037332252,-0.19695957,-5.110844305,"Up"]
[1863,"WP_NOTCH_SIGNALING_PATHWAY",2.082437013,0.017483682,0.070613062,0.03743515,-0.220362963,-5.113177691,"Up"]
[1862,"REACTOME_CD28_CO_STIMULATION",2.079610763,0.022022008,0.070997618,0.037694135,-0.198426236,-5.11902101,"Up"]
[1861,"REACTOME_AKT_PHOSPHORYLATES_TARGETS_IN_THE_CYTOSOL",2.079429913,0.025775354,0.070997618,0.037710759,-0.317678958,-5.119394651,"Up"]
[1860,"WP_DNA_MISMATCH_REPAIR",2.076148463,0.019306123,0.0715222,0.038013483,-0.162436424,-5.126168607,"Up"]
[1859,"REACTOME_MRNA_CAPPING",2.073708711,0.021257676,0.071902629,0.038239896,-0.230174273,-5.131198128,"Up"]
[1858,"REACTOME_TRANSPORT_OF_SMALL_MOLECULES",2.071161102,0.007947565,0.072303685,0.038477542,-0.078189387,-5.136443711,"Up"]
[1857,"REACTOME_ACYL_CHAIN_REMODELLING_OF_PI",2.06906127,0.020287063,0.072581656,0.038674362,0.123156721,-5.140762485,"Up"]
[1856,"KEGG_OTHER_GLYCAN_DEGRADATION",2.068019227,0.023403539,0.07271959,0.038772351,-0.19934319,-5.142904061,"Up"]
[1855,"REACTOME_SYNTHESIS_OF_PIPS_AT_THE_PLASMA_MEMBRANE",2.063082887,0.014946399,0.073502733,0.039239418,-0.155935767,-5.153034486,"Up"]
[1854,"REACTOME_INTERLEUKIN_35_SIGNALLING",2.060615902,0.02716562,0.073896697,0.039474625,-0.000665616,-5.158088233,"Up"]
[1853,"REACTOME_SIGNALING_BY_HEDGEHOG",2.058151058,0.020738386,0.074245236,0.039710824,-0.142958231,-5.163131584,"Up"]
[1852,"REACTOME_RECOGNITION_AND_ASSOCIATION_OF_DNA_GLYCOSYLASE_WITH_SITE_CONTAINING_AN_AFFECTED_PURINE",2.057128145,0.02555958,0.074382322,0.039809198,-0.104385707,-5.165222815,"Up"]
[1851,"REACTOME_NEGATIVE_REGULATION_OF_TCF_DEPENDENT_SIGNALING_BY_DVL_INTERACTING_PROTEINS",2.051212158,0.030207369,0.075358132,0.040382212,-0.15979523,-5.177297084,"Up"]
[1850,"REACTOME_RESOLUTION_OF_ABASIC_SITES_AP_SITES",2.046434723,0.017133962,0.076183276,0.040850042,-0.192155564,-5.187022353,"Up"]
[1849,"WP_ALZHEIMERS_DISEASE",2.043094036,0.015140133,0.076733254,0.041179903,-0.139508314,-5.193809468,"Up"]
[1848,"REACTOME_DEACTIVATION_OF_THE_BETA_CATENIN_TRANSACTIVATING_COMPLEX",2.042925193,0.020324503,0.076733254,0.041196634,-0.179443154,-5.194152203,"Up"]
[1847,"REACTOME_MYD88_INDEPENDENT_TLR4_CASCADE",2.036290995,0.015618411,0.077819819,0.041858623,-0.182421904,-5.207596745,"Up"]
[1846,"REACTOME_THROMBOXANE_SIGNALLING_THROUGH_TP_RECEPTOR",2.033641738,0.024514062,0.078266933,0.042125483,-0.130125278,-5.212953436,"Up"]
[1845,"REACTOME_ERCC6_CSB_AND_EHMT2_G9A_POSITIVELY_REGULATE_RRNA_EXPRESSION",2.027937692,0.025963208,0.07919487,0.042704947,-0.294105473,-5.224463214,"Up"]
[1844,"REACTOME_ACTIVATED_NTRK2_SIGNALS_THROUGH_CDK5",2.026490864,0.0401466,0.079419814,0.042852995,-0.127553178,-5.227377547,"Up"]
[1843,"BIOCARTA_CHEMICAL_PATHWAY",2.01544534,0.022502282,0.081439477,0.043997616,-0.197300044,-5.249558175,"Up"]
[1842,"REACTOME_MITOPHAGY",2.009696552,0.028788708,0.082471308,0.0446035,-0.193968104,-5.261054612,"Up"]
[1841,"BIOCARTA_RANBP2_PATHWAY",2.009629424,0.026972085,0.082471308,0.044610616,-0.279199999,-5.261188663,"Up"]
[1840,"REACTOME_METABOLISM_OF_STEROIDS",2.00798905,0.009262873,0.082741819,0.044784811,-0.157375648,-5.264462979,"Up"]
[1839,"REACTOME_PI_METABOLISM",2.003927073,0.011822148,0.083491368,0.045218632,-0.16202549,-5.272559551,"Up"]
[1838,"REACTOME_SYNTHESIS_OF_DOLICHYL_PHOSPHATE",2.00284482,0.02642828,0.083653862,0.045334814,-0.198685326,-5.274714008,"Up"]
[1837,"PID_TCPTP_PATHWAY",2.001088086,0.01884014,0.083950667,0.045523938,-0.208780153,-5.278208694,"Up"]
[1836,"WP_GASTRIC_CANCER_NETWORK_2",2.000787979,0.019489311,0.083958221,0.045556313,-0.171387781,-5.278805394,"Up"]
[1835,"REACTOME_PCNA_DEPENDENT_LONG_PATCH_BASE_EXCISION_REPAIR",1.994243639,0.021917962,0.085215362,0.046267149,-0.191611398,-5.29179529,"NoSignifi"]
[1834,"REACTOME_FORMATION_OF_INCISION_COMPLEX_IN_GG_NER",1.992262234,0.022535135,0.085488702,0.0464842,-0.203720216,-5.295719831,"NoSignifi"]
[1833,"REACTOME_MISMATCH_REPAIR",1.991370498,0.020746403,0.085583196,0.046582164,-0.198092763,-5.297484813,"NoSignifi"]
[1832,"WP_NEUROINFLAMMATION",1.990118063,0.029346186,0.085783438,0.046720047,-0.143833405,-5.299962386,"NoSignifi"]
[1831,"BIOCARTA_CALCINEURIN_PATHWAY",1.989305522,0.026722296,0.085894904,0.046809685,-0.180939729,-5.301568928,"NoSignifi"]
[1830,"PID_CD40_PATHWAY",1.982124736,0.018878568,0.087090977,0.04760817,-0.244850869,-5.315738253,"NoSignifi"]
[1829,"BIOCARTA_IL2_PATHWAY",1.980874247,0.023203909,0.087293693,0.047748386,-0.212413857,-5.318200535,"NoSignifi"]
[1828,"REACTOME_JOSEPHIN_DOMAIN_DUBS",1.977666567,0.039579394,0.087900029,0.048109649,-0.225838551,-5.32450956,"NoSignifi"]
[1827,"REACTOME_TFAP2_AP_2_FAMILY_REGULATES_TRANSCRIPTION_OF_CELL_CYCLE_FACTORS",1.962878086,0.034246582,0.090607349,0.04980505,-0.355028964,-5.353464587,"NoSignifi"]
[1826,"REACTOME_BETA_DEFENSINS",1.960538831,0.020460693,0.090991982,0.05007777,0.186214991,-5.358024891,"NoSignifi"]
[1825,"REACTOME_SUMOYLATION_OF_TRANSCRIPTION_FACTORS",1.956011496,0.02111941,0.091605159,0.050609144,-0.243217921,-5.366835405,"NoSignifi"]
[1824,"REACTOME_RUNX1_REGULATES_TRANSCRIPTION_OF_GENES_INVOLVED_IN_DIFFERENTIATION_OF_MYELOID_CELLS",1.956007376,0.033491892,0.091605159,0.050609629,-0.21348594,-5.366843413,"NoSignifi"]
[1823,"WP_16P112_PROXIMAL_DELETION_SYNDROME",1.955824342,0.015480664,0.091605159,0.050631211,-0.186244279,-5.367199182,"NoSignifi"]
[1822,"REACTOME_PHOSPHORYLATION_OF_EMI1",1.955435824,0.019620198,0.091632251,0.050677048,0.071930635,-5.367954249,"NoSignifi"]
[1821,"PID_BARD1_PATHWAY",1.954176847,0.019077883,0.091845317,0.050825819,-0.089988901,-5.370399985,"NoSignifi"]
[1820,"WP_INTERACTOME_OF_POLYCOMB_REPRESSIVE_COMPLEX_2_PRC2",1.944724943,0.026807407,0.093600002,0.051954464,-0.277358012,-5.388711502,"NoSignifi"]
[1819,"WP_HOSTPATHOGEN_INTERACTION_OF_HUMAN_CORONAVIRUSES_MAPK_SIGNALING",1.938867542,0.018906095,0.094821409,0.052664366,-0.228534524,-5.400014876,"NoSignifi"]
[1818,"REACTOME_NUCLEAR_ENVELOPE_BREAKDOWN",1.934169333,0.012967952,0.095741036,0.053239626,-0.231607824,-5.409056743,"NoSignifi"]
[1817,"REACTOME_HDL_ASSEMBLY",1.933768127,0.027692102,0.095771804,0.053288993,-0.254080757,-5.409827865,"NoSignifi"]
[1816,"REACTOME_TOLL_LIKE_RECEPTOR_9_TLR9_CASCADE",1.929361009,0.014053216,0.096692406,0.053833798,-0.183601563,-5.418287904,"NoSignifi"]
[1815,"REACTOME_PURINE_RIBONUCLEOSIDE_MONOPHOSPHATE_BIOSYNTHESIS",1.927530872,0.030061137,0.097042505,0.054061402,-0.224506718,-5.421795443,"NoSignifi"]
[1814,"WP_AGERAGE_PATHWAY",1.922277786,0.015849636,0.098163872,0.054719167,-0.173446295,-5.431844795,"NoSignifi"]
[1813,"PID_FGF_PATHWAY",1.921764368,0.015249216,0.098220493,0.054783812,-0.196485305,-5.432825516,"NoSignifi"]
[1812,"WP_IL4_SIGNALING_PATHWAY",1.91818074,0.014850111,0.098972885,0.055236804,-0.204077775,-5.439663635,"NoSignifi"]
[1811,"REACTOME_SIGNALING_BY_HIPPO",1.916597101,0.02192478,0.099141359,0.055437978,-0.210406559,-5.442681415,"NoSignifi"]
[1810,"WP_INTERLEUKIN11_SIGNALING_PATHWAY",1.916389483,0.017154572,0.099141359,0.055464398,-0.20263938,-5.443076866,"NoSignifi"]
[1809,"PID_FRA_PATHWAY",1.915385113,0.018813264,0.099250569,0.055592353,-0.17580292,-5.444989298,"NoSignifi"]
[1808,"REACTOME_DEADENYLATION_DEPENDENT_MRNA_DECAY",1.90951472,0.017131641,0.100415214,0.056345166,-0.229881603,-5.456147199,"NoSignifi"]
[1807,"REACTOME_SCAVENGING_OF_HEME_FROM_PLASMA",1.909507023,0.015795947,0.100415214,0.056346159,0.388962286,-5.456161806,"NoSignifi"]
[1806,"REACTOME_REGULATION_OF_BACH1_ACTIVITY",1.907675193,0.040620521,0.100716038,0.056582806,-0.165185866,-5.459636581,"NoSignifi"]
[1805,"WP_ALZHEIMERS_DISEASE_AND_MIRNA_EFFECTS",1.893882543,0.014005875,0.103872905,0.058391337,-0.13762243,-5.485692998,"NoSignifi"]
[1804,"REACTOME_INTRACELLULAR_SIGNALING_BY_SECOND_MESSENGERS",1.892273133,0.013608093,0.10419139,0.058605464,-0.180651398,-5.488721145,"NoSignifi"]
[1803,"BIOCARTA_CBL_PATHWAY",1.890121391,0.02483459,0.104576926,0.058892765,-0.181850761,-5.492765699,"NoSignifi"]
[1802,"REACTOME_DEUBIQUITINATION",1.889787304,0.014538053,0.104593767,0.058937478,-0.198581306,-5.493393261,"NoSignifi"]
[1801,"BIOCARTA_IGF1MTOR_PATHWAY",1.879272794,0.02355569,0.106861261,0.060359156,-0.256563416,-5.513087604,"NoSignifi"]
[1800,"REACTOME_G_PROTEIN_ACTIVATION",1.877385285,0.024122489,0.107254428,0.060617356,-0.121760113,-5.516611437,"NoSignifi"]
[1799,"REACTOME_TICAM1_DEPENDENT_ACTIVATION_OF_IRF3_IRF7",1.876780652,0.033220434,0.107337148,0.06070026,-0.170016787,-5.517739493,"NoSignifi"]
[1798,"REACTOME_SYNTHESIS_SECRETION_AND_DEACYLATION_OF_GHRELIN",1.874829921,0.023568962,0.107682987,0.060968374,0.05576928,-5.521376482,"NoSignifi"]
[1797,"REACTOME_LOSS_OF_FUNCTION_OF_SMAD2_3_IN_CANCER",1.872483231,0.030000131,0.108190589,0.06129221,-0.341331491,-5.525746714,"NoSignifi"]
[1796,"WP_IMATINIB_AND_CHRONIC_MYELOID_LEUKEMIA",1.868295107,0.019542759,0.109087301,0.0618737,-0.131134934,-5.533532689,"NoSignifi"]
[1795,"REACTOME_HIV_TRANSCRIPTION_INITIATION",1.862495539,0.016065181,0.110389155,0.062686465,-0.22003161,-5.544285752,"NoSignifi"]
[1794,"REACTOME_GLUCOCORTICOID_BIOSYNTHESIS",1.856697337,0.013837413,0.111570893,0.063507851,0.347141764,-5.555002986,"NoSignifi"]
[1793,"REACTOME_TOLL_LIKE_RECEPTOR_TLR1_TLR2_CASCADE",1.854171028,0.012787072,0.112071865,0.063868506,-0.170845154,-5.559662131,"NoSignifi"]
[1792,"REACTOME_SIGNALLING_TO_RAS",1.851120824,0.019000769,0.112706688,0.064306207,-0.198238994,-5.565279046,"NoSignifi"]
[1791,"WP_AUTOPHAGY",1.849661676,0.016101923,0.113008491,0.064516468,-0.229377671,-5.56796279,"NoSignifi"]
[1790,"WP_INTERLEUKIN1_IL1_STRUCTURAL_PATHWAY",1.849286877,0.013854832,0.113036565,0.064570567,-0.226644344,-5.568651801,"NoSignifi"]
[1789,"WP_MITOCHONDRIAL_COMPLEX_IV_ASSEMBLY",1.845158167,0.02524789,0.114016947,0.065169,-0.161300739,-5.576232596,"NoSignifi"]
[1788,"REACTOME_PROTEIN_LOCALIZATION",1.844416691,0.014772271,0.114138564,0.065276956,-0.150479093,-5.577592245,"NoSignifi"]
[1787,"REACTOME_P75NTR_NEGATIVELY_REGULATES_CELL_CYCLE_VIA_SC1",1.842346118,0.027541135,0.114599564,0.065579205,-0.208713439,-5.581386181,"NoSignifi"]
[1786,"REACTOME_IRON_UPTAKE_AND_TRANSPORT",1.841958937,0.020834624,0.114631083,0.065635851,-0.172808661,-5.582095146,"NoSignifi"]
[1785,"REACTOME_HEDGEHOG_OFF_STATE",1.841041394,0.021707838,0.114798283,0.065770252,-0.149445989,-5.583774661,"NoSignifi"]
[1784,"KEGG_FOCAL_ADHESION",1.839258478,0.016652491,0.115136008,0.066032063,-0.146340303,-5.587035813,"NoSignifi"]
[1783,"REACTOME_ACTIVATION_OF_IRF3_IRF7_MEDIATED_BY_TBK1_IKK_EPSILON",1.839195673,0.029297637,0.115136008,0.066041301,-0.184719312,-5.587150634,"NoSignifi"]
[1782,"REACTOME_MITOCHONDRIAL_TRNA_AMINOACYLATION",1.834241127,0.019244062,0.116207714,0.066773446,-0.097348755,-5.596196212,"NoSignifi"]
[1781,"REACTOME_SIGNALING_BY_EGFR_IN_CANCER",1.832379463,0.023502012,0.116621122,0.067050271,-0.181886678,-5.599588792,"NoSignifi"]
[1780,"REACTOME_ACROSOME_REACTION_AND_SPERM_OOCYTE_MEMBRANE_BINDING",1.826974895,0.041148221,0.117821171,0.06785928,0.126284362,-5.609418287,"NoSignifi"]
[1779,"PID_ALPHA_SYNUCLEIN_PATHWAY",1.823937966,0.016520767,0.118547247,0.068317393,-0.0647977,-5.614928971,"NoSignifi"]
[1778,"REACTOME_HEME_BIOSYNTHESIS",1.821165821,0.02132294,0.119137463,0.068737782,-0.164886504,-5.61995121,"NoSignifi"]
[1777,"BIOCARTA_TERC_PATHWAY",1.819513589,0.031008157,0.119503721,0.068989349,-0.282381594,-5.622940908,"NoSignifi"]
[1776,"WP_STEROID_BIOSYNTHESIS",1.817977252,0.028466873,0.119840177,0.069223949,-0.089049586,-5.625718466,"NoSignifi"]
[1775,"BIOCARTA_TFF_PATHWAY",1.815654563,0.021159063,0.120386151,0.06957987,-0.232002524,-5.629913239,"NoSignifi"]
[1774,"WP_SUDDEN_INFANT_DEATH_SYNDROME_SIDS_SUSCEPTIBILITY_PATHWAYS",1.815254359,0.012373327,0.120422342,0.069641348,-0.075699634,-5.630635466,"NoSignifi"]
[1773,"REACTOME_RAB_GEFS_EXCHANGE_GTP_FOR_GDP_ON_RABS",1.812494046,0.011786445,0.121087142,0.070066591,-0.20019664,-5.635612543,"NoSignifi"]
[1772,"BIOCARTA_STRESS_PATHWAY",1.810352669,0.017745206,0.121589014,0.070397951,-0.183340739,-5.639468428,"NoSignifi"]
[1771,"WP_TYPE_2_PAPILLARY_RENAL_CELL_CARCINOMA",1.809478379,0.017714039,0.121752491,0.070533609,-0.221342458,-5.641041417,"NoSignifi"]
[1770,"REACTOME_RUNX3_REGULATES_WNT_SIGNALING",1.807638591,0.028088906,0.122175434,0.070819779,-0.180446278,-5.644349023,"NoSignifi"]
[1769,"REACTOME_REGULATION_OF_PTEN_STABILITY_AND_ACTIVITY",1.795302809,0.02625814,0.125382522,0.072763249,-0.185578043,-5.666439901,"NoSignifi"]
[1768,"REACTOME_CONDENSATION_OF_PROMETAPHASE_CHROMOSOMES",1.791461102,0.023563938,0.126367366,0.073377346,-0.146137142,-5.673288832,"NoSignifi"]
[1767,"REACTOME_TERMINATION_OF_O_GLYCAN_BIOSYNTHESIS",1.790599332,0.015494888,0.126532206,0.07351568,0.146181089,-5.674823172,"NoSignifi"]
[1766,"REACTOME_DISSOLUTION_OF_FIBRIN_CLOT",1.784861294,0.025953063,0.127904495,0.074442225,-0.164788734,-5.685020721,"NoSignifi"]
[1765,"REACTOME_NUCLEOTIDE_EXCISION_REPAIR",1.77818004,0.014698306,0.129553858,0.075533085,-0.207944572,-5.696853429,"NoSignifi"]
[1764,"REACTOME_RUNX3_REGULATES_IMMUNE_RESPONSE_AND_CELL_MIGRATION",1.777416361,0.017728645,0.129694216,0.075658599,0.196834033,-5.698203114,"NoSignifi"]
[1763,"REACTOME_SIGNALING_BY_WNT",1.770896308,0.014470638,0.13146717,0.076737152,-0.149374952,-5.709702756,"NoSignifi"]
[1762,"REACTOME_METALLOPROTEASE_DUBS",1.769350859,0.021775188,0.131756233,0.076994632,-0.244428879,-5.712422343,"NoSignifi"]
[1761,"KEGG_CYTOSOLIC_DNA_SENSING_PATHWAY",1.768711611,0.01281419,0.131862834,0.07710134,-0.159119705,-5.713546559,"NoSignifi"]
[1760,"BIOCARTA_NDKDYNAMIN_PATHWAY",1.768239848,0.024820695,0.131921657,0.077180168,-0.226027719,-5.714375968,"NoSignifi"]
[1759,"REACTOME_PLATELET_ACTIVATION_SIGNALING_AND_AGGREGATION",1.767116224,0.013886956,0.132166932,0.07736818,-0.114615233,-5.716350531,"NoSignifi"]
[1758,"BIOCARTA_RECK_PATHWAY",1.766387035,0.037818536,0.132299584,0.077490393,-0.171237132,-5.717631276,"NoSignifi"]
[1757,"BIOCARTA_PS1_PATHWAY",1.764530505,0.022643985,0.132682063,0.077802259,-0.195452816,-5.720889702,"NoSignifi"]
[1756,"KEGG_HEDGEHOG_SIGNALING_PATHWAY",1.761502873,0.011526353,0.133397263,0.078313045,-0.062257226,-5.726196223,"NoSignifi"]
[1755,"REACTOME_INTERLEUKIN_27_SIGNALING",1.745990382,0.030643997,0.137219895,0.080973141,-0.115529466,-5.753242413,"NoSignifi"]
[1754,"REACTOME_METABOLISM_OF_AMINO_ACIDS_AND_DERIVATIVES",1.745328694,0.025168569,0.137263175,0.081088221,-0.098896409,-5.75439077,"NoSignifi"]
[1753,"WP_DOPAMINE_METABOLISM",1.744202927,0.024495364,0.137511761,0.081284318,-0.163798786,-5.756343539,"NoSignifi"]
[1752,"REACTOME_DEADENYLATION_OF_MRNA",1.738912521,0.021851848,0.138921176,0.082211016,-0.247723834,-5.765503514,"NoSignifi"]
[1751,"WP_ANGIOGENESIS",1.733222382,0.019317577,0.140541591,0.083217284,-0.224448814,-5.775324639,"NoSignifi"]
[1750,"PID_TCR_RAS_PATHWAY",1.731438023,0.020387863,0.140917659,0.083534887,-0.227973256,-5.778397817,"NoSignifi"]
[1749,"REACTOME_RUNX3_REGULATES_NOTCH_SIGNALING",1.721850407,0.022909713,0.143743217,0.08525827,-0.183750088,-5.794856409,"NoSignifi"]
[1748,"REACTOME_REGULATION_OF_EXPRESSION_OF_SLITS_AND_ROBOS",1.721497629,0.036693414,0.143769405,0.085322227,-0.164613047,-5.795460268,"NoSignifi"]
[1747,"REACTOME_IRS_ACTIVATION",1.718035252,0.031587733,0.144748435,0.085952001,-0.320415845,-5.801380361,"NoSignifi"]
[1746,"PID_HEDGEHOG_GLI_PATHWAY",1.711659124,0.01660103,0.146551842,0.08712159,-0.230943939,-5.812251396,"NoSignifi"]
[1745,"REACTOME_CTLA4_INHIBITORY_SIGNALING",1.703998409,0.020127239,0.148691449,0.088543779,-0.264572887,-5.825259307,"NoSignifi"]
[1744,"PID_TELOMERASE_PATHWAY",1.698985371,0.015185786,0.150101452,0.08948453,-0.214075219,-5.833739969,"NoSignifi"]
[1743,"KEGG_ALZHEIMERS_DISEASE",1.690023323,0.018489324,0.152783561,0.091186416,-0.145648269,-5.848839179,"NoSignifi"]
[1742,"REACTOME_PROTEIN_FOLDING",1.682532512,0.01556176,0.155025335,0.092628812,-0.155531581,-5.86139857,"NoSignifi"]
[1741,"REACTOME_ABC_FAMILY_PROTEINS_MEDIATED_TRANSPORT",1.679577422,0.019341974,0.155898175,0.09320285,-0.13135266,-5.86633789,"NoSignifi"]
[1740,"REACTOME_DNA_DAMAGE_REVERSAL",1.674129629,0.022762781,0.157592029,0.09426859,-0.247386658,-5.875420978,"NoSignifi"]
[1739,"KEGG_RIBOSOME",1.670979342,0.049872084,0.158506782,0.094889322,-0.162425222,-5.880660015,"NoSignifi"]
[1738,"REACTOME_INLA_MEDIATED_ENTRY_OF_LISTERIA_MONOCYTOGENES_INTO_HOST_CELLS",1.67081116,0.036698814,0.158506782,0.094922552,-0.193271032,-5.880939431,"NoSignifi"]
[1737,"REACTOME_DEFECTIVE_CHSY1_CAUSES_TPBS",1.668073587,0.027360809,0.159322603,0.095464773,{"v":9.68e-05,"d":"9.68E-05"},-5.885483665,"NoSignifi"]
[1736,"REACTOME_ER_TO_GOLGI_ANTEROGRADE_TRANSPORT",1.667354267,0.013676779,0.159471423,0.095607657,-0.181236828,-5.886676467,"NoSignifi"]
[1735,"WP_ESTROGEN_METABOLISM",1.665526765,0.016175274,0.159898541,0.095971438,0.240223576,-5.88970459,"NoSignifi"]
[1734,"REACTOME_DOWNREGULATION_OF_ERBB2_ERBB3_SIGNALING",1.664025351,0.028203211,0.160307912,0.096271138,-0.216248696,-5.892189914,"NoSignifi"]
[1733,"WP_MAPK_CASCADE",1.660565733,0.014856645,0.161372091,0.09696457,-0.261226602,-5.897908193,"NoSignifi"]
[1732,"PID_ATM_PATHWAY",1.658884396,0.012966449,0.16168946,0.097303012,-0.183415622,-5.900682929,"NoSignifi"]
[1731,"KEGG_OXIDATIVE_PHOSPHORYLATION",1.656299805,0.022644712,0.162440024,0.097825114,-0.156518521,-5.904942854,"NoSignifi"]
[1730,"REACTOME_GLUTATHIONE_CONJUGATION",1.653943624,0.015600854,0.16314236,0.098303026,-0.099014093,-5.908820542,"NoSignifi"]
[1729,"REACTOME_UNWINDING_OF_DNA",1.648491953,0.014568309,0.164805129,0.09941596,0.034573588,-5.917771535,"NoSignifi"]
[1728,"REACTOME_EUKARYOTIC_TRANSLATION_ELONGATION",1.647930017,0.048756197,0.16490417,0.099531247,-0.15931084,-5.918692493,"NoSignifi"]
[1727,"KEGG_RIBOFLAVIN_METABOLISM",1.646595787,0.018695555,0.165266172,0.099805404,-0.141706483,-5.920877907,"NoSignifi"]
[1726,"REACTOME_RESPONSE_OF_EIF2AK4_GCN2_TO_AMINO_ACID_DEFICIENCY",1.645092297,0.045155104,0.165594219,0.100115063,-0.157772706,-5.923338447,"NoSignifi"]
[1725,"REACTOME_SEALING_OF_THE_NUCLEAR_ENVELOPE_NE_BY_ESCRT_III",1.63957797,0.019080659,0.167111233,0.101257362,-0.140997029,-5.932343748,"NoSignifi"]
[1724,"WP_KETONE_BODIES_SYNTHESIS_AND_DEGRADATION",1.637915634,0.030062704,0.167589737,0.101603748,-0.267826639,-5.93505255,"NoSignifi"]
[1723,"PID_INTEGRIN_CS_PATHWAY",1.624742335,0.013744879,0.171432084,0.104382201,0.038257841,-5.956421747,"NoSignifi"]
[1722,"REACTOME_TRAF6_MEDIATED_IRF7_ACTIVATION_IN_TLR7_8_OR_9_SIGNALING",1.624681586,0.033316616,0.171432084,0.104395152,-0.186084288,-5.956519894,"NoSignifi"]
[1721,"REACTOME_CONSTITUTIVE_SIGNALING_BY_OVEREXPRESSED_ERBB2",1.622987487,0.025867028,0.171835946,0.104756841,-0.282881481,-5.959255402,"NoSignifi"]
[1720,"REACTOME_CD28_DEPENDENT_VAV1_PATHWAY",1.622121591,0.032533246,0.172044768,0.104942093,-0.219285447,-5.960652489,"NoSignifi"]
[1719,"REACTOME_INTERLEUKIN_17_SIGNALING",1.620425354,0.013261295,0.172545672,0.105305745,-0.19613022,-5.963387144,"NoSignifi"]
[1718,"REACTOME_SRP_DEPENDENT_COTRANSLATIONAL_PROTEIN_TARGETING_TO_MEMBRANE",1.620128108,0.042303551,0.172555028,0.105369574,-0.160749006,-5.963866067,"NoSignifi"]
[1717,"REACTOME_PROTEIN_UBIQUITINATION",1.617316222,0.017618681,0.173450653,0.105974902,-0.223458471,-5.968392243,"NoSignifi"]
[1716,"REACTOME_PROLACTIN_RECEPTOR_SIGNALING",1.616172948,0.020861469,0.17375898,0.106221808,-0.1838912,-5.970230282,"NoSignifi"]
[1715,"WP_CYTOPLASMIC_RIBOSOMAL_PROTEINS",1.608404697,0.047697761,0.176011663,0.107911579,-0.157580204,-5.982684953,"NoSignifi"]
[1714,"BIOCARTA_ETC_PATHWAY",1.60312176,0.027056798,0.177737269,0.109072854,-0.257939909,-5.991120785,"NoSignifi"]
[1713,"REACTOME_SIGNALING_BY_NOTCH4",1.602292645,0.02115798,0.177745877,0.109256002,-0.164519763,-5.992442209,"NoSignifi"]
[1712,"REACTOME_ORGANELLE_BIOGENESIS_AND_MAINTENANCE",1.601524212,0.009858045,0.17792206,0.109425962,-0.150036033,-5.993666311,"NoSignifi"]
[1711,"WP_NRF2ARE_REGULATION",1.601087792,0.019540401,0.177981688,0.109522581,-0.213526632,-5.994361259,"NoSignifi"]
[1710,"REACTOME_RAS_SIGNALING_DOWNSTREAM_OF_NF1_LOSS_OF_FUNCTION_VARIANTS",1.59925282,0.025730329,0.178545342,0.109929567,-0.272275188,-5.997281179,"NoSignifi"]
[1709,"REACTOME_DOWNREGULATION_OF_TGF_BETA_RECEPTOR_SIGNALING",1.591936432,0.021085612,0.180804645,0.1115642,-0.221113701,-6.008890254,"NoSignifi"]
[1708,"WP_DUAL_HIJACK_MODEL_OF_VIF_IN_HIV_INFECTION",1.587564863,0.031098593,0.182239148,0.112550023,-0.202603142,-6.015801383,"NoSignifi"]
[1707,"REACTOME_VXPX_CARGO_TARGETING_TO_CILIUM",1.587467262,0.018969393,0.182239148,0.112572111,-0.266662536,-6.015955467,"NoSignifi"]
[1706,"REACTOME_TICAM1_RIP1_MEDIATED_IKK_COMPLEX_RECRUITMENT",1.586549676,0.024754526,0.182476093,0.112779936,-0.140620289,-6.017403608,"NoSignifi"]
[1705,"REACTOME_PROTON_COUPLED_MONOCARBOXYLATE_TRANSPORT",1.581950961,0.027911684,0.184068406,0.113826067,-0.269887445,-6.02464875,"NoSignifi"]
[1704,"REACTOME_G_ALPHA_Z_SIGNALLING_EVENTS",1.578900976,0.013660396,0.185096374,0.114524095,-0.074907727,-6.029442342,"NoSignifi"]
[1703,"BIOCARTA_PDGF_PATHWAY",1.578436354,0.016928033,0.185167913,0.114630725,-0.227476037,-6.030171768,"NoSignifi"]
[1702,"WP_LUNG_FIBROSIS",1.577281971,0.012337673,0.185495488,0.114895993,-0.112576787,-6.031983149,"NoSignifi"]
[1701,"PID_SHP2_PATHWAY",1.574775436,0.012842976,0.186326755,0.115473637,-0.185939732,-6.035911681,"NoSignifi"]
[1700,"REACTOME_HIV_TRANSCRIPTION_ELONGATION",1.574202345,0.015679743,0.186439056,0.11560603,-0.218420395,-6.036809021,"NoSignifi"]
[1699,"WP_EPITHELIAL_TO_MESENCHYMAL_TRANSITION_IN_COLORECTAL_CANCER",1.572724359,0.009703795,0.186889068,0.115948017,-0.142451829,-6.039121732,"NoSignifi"]
[1698,"KEGG_CARDIAC_MUSCLE_CONTRACTION",1.569195342,0.019479295,0.18810831,0.116767806,-0.12611345,-6.044635075,"NoSignifi"]
[1697,"PID_ECADHERIN_NASCENT_AJ_PATHWAY",1.568542769,0.019688941,0.188159033,0.116919896,-0.227065718,-6.045653228,"NoSignifi"]
[1696,"REACTOME_CYTOCHROME_C_MEDIATED_APOPTOTIC_RESPONSE",1.568516417,0.019490272,0.188159033,0.116926041,-0.242399745,-6.045694334,"NoSignifi"]
[1695,"REACTOME_TRANSCRIPTIONAL_REGULATION_OF_PLURIPOTENT_STEM_CELLS",1.564981847,0.014938361,0.189386426,0.117752557,-0.045193366,-6.05120159,"NoSignifi"]
[1694,"REACTOME_NERVOUS_SYSTEM_DEVELOPMENT",1.56312135,0.017860047,0.189986184,0.118189451,-0.131619344,-6.054095474,"NoSignifi"]
[1693,"WP_ADIPOGENESIS",1.561254572,0.010200958,0.190589715,0.118629098,-0.174717456,-6.056995676,"NoSignifi"]
[1692,"WP_VITAMIN_B12_METABOLISM",1.559257888,0.010666934,0.191201785,0.119100759,-0.02889858,-6.060093873,"NoSignifi"]
[1691,"KEGG_GALACTOSE_METABOLISM",1.559025485,0.016191056,0.191201785,0.119155753,-0.226895056,-6.060454229,"NoSignifi"]
[1690,"WP_PDGFRBETA_PATHWAY",1.558824754,0.01636693,0.191201785,0.119203268,-0.234554582,-6.060765433,"NoSignifi"]
[1689,"WP_1Q211_COPY_NUMBER_VARIATION_SYNDROME",1.555863953,0.015473122,0.192121145,0.119905854,-0.068461574,-6.06535107,"NoSignifi"]
[1688,"BIOCARTA_ERK_PATHWAY",1.554578295,0.016866584,0.192507693,0.120211944,-0.238354031,-6.067339568,"NoSignifi"]
[1687,"REACTOME_TRAF6_MEDIATED_INDUCTION_OF_TAK1_COMPLEX_WITHIN_TLR4_COMPLEX",1.55241523,0.027213614,0.193230377,0.120728309,-0.12526256,-6.07068143,"NoSignifi"]
[1686,"REACTOME_NEF_MEDIATED_DOWNREGULATION_OF_MHC_CLASS_I_COMPLEX_CELL_SURFACE_EXPRESSION",1.551059381,0.023784106,0.193645444,0.121052861,-0.207010329,-6.072773804,"NoSignifi"]
[1685,"WP_EFFECT_OF_PROGERIN_ON_GENES_INVOLVED_IN_HUTCHINSONGILFORD_PROGERIA_SYNDROME",1.547598353,0.018404428,0.19476581,0.121884431,-0.249436732,-6.078106664,"NoSignifi"]
[1684,"KEGG_NOTCH_SIGNALING_PATHWAY",1.546731826,0.011973072,0.194994667,0.122093326,-0.222449433,-6.079439977,"NoSignifi"]
[1683,"REACTOME_FERTILIZATION",1.543709346,0.016195542,0.196056406,0.122824155,0.219194126,-6.084084791,"NoSignifi"]
[1682,"WP_CANONICAL_AND_NONCANONICAL_TGFB_SIGNALING",1.543365986,0.019980017,0.196083855,0.122907394,-0.313064416,-6.084611879,"NoSignifi"]
[1681,"REACTOME_HCMV_INFECTION",1.542907278,0.012713926,0.196155972,0.123018666,-0.175584322,-6.085315852,"NoSignifi"]
[1680,"REACTOME_RECOGNITION_OF_DNA_DAMAGE_BY_PCNA_CONTAINING_REPLICATION_COMPLEX",1.541550427,0.018546541,0.196575955,0.123348267,-0.197595963,-6.087396974,"NoSignifi"]
[1679,"REACTOME_SIGNALING_BY_THE_B_CELL_RECEPTOR_BCR",1.537539757,0.018070464,0.197880128,0.124326558,-0.166267156,-6.093537813,"NoSignifi"]
[1678,"WP_4HYDROXYTAMOXIFEN_DEXAMETHASONE_AND_RETINOIC_ACIDS_REGULATION_OF_P27_EXPRESSION",1.537376284,0.015857604,0.197880128,0.124366561,-0.250827756,-6.093787773,"NoSignifi"]
[1677,"REACTOME_CONSTITUTIVE_SIGNALING_BY_LIGAND_RESPONSIVE_EGFR_CANCER_VARIANTS",1.536021025,0.022133904,0.198302146,0.124698588,-0.218741824,-6.095859017,"NoSignifi"]
[1676,"REACTOME_SELENOAMINO_ACID_METABOLISM",1.533031303,0.041572985,0.199150819,0.12543349,-0.146301606,-6.100421771,"NoSignifi"]
[1675,"WP_DDX1_AS_A_REGULATORY_COMPONENT_OF_THE_DROSHA_MICROPROCESSOR",1.532321018,0.023074361,0.199322221,0.125608581,-0.240831017,-6.101504466,"NoSignifi"]
[1674,"REACTOME_REGULATION_OF_TP53_EXPRESSION_AND_DEGRADATION",1.530293906,0.015252547,0.199903146,0.126109327,-0.233755843,-6.104591664,"NoSignifi"]
[1673,"REACTOME_CDC42_GTPASE_CYCLE",1.527343586,0.0077016,0.200848349,0.126840907,-0.147705796,-6.109077579,"NoSignifi"]
[1672,"BIOCARTA_SPRY_PATHWAY",1.524060676,0.015790733,0.201928128,0.12765884,-0.259447547,-6.114059041,"NoSignifi"]
[1671,"WP_HEME_BIOSYNTHESIS",1.518996526,0.021260077,0.203719555,0.12892861,-0.247217066,-6.121722373,"NoSignifi"]
[1670,"REACTOME_NONSENSE_MEDIATED_DECAY_NMD",1.518570708,0.037970509,0.203736014,0.129035825,-0.160609454,-6.122365582,"NoSignifi"]
[1669,"REACTOME_PTEN_REGULATION",1.51841015,0.015840516,0.203736014,0.129076269,-0.208986232,-6.122608063,"NoSignifi"]
[1668,"BIOCARTA_EIF2_PATHWAY",1.515756445,0.024622007,0.204684558,0.129746156,-0.231850803,-6.126612082,"NoSignifi"]
[1667,"WP_INFLUENCE_OF_LAMINOPATHIES_ON_WNT_SIGNALING",1.515240031,0.013960911,0.204781896,0.129876831,-0.200043762,-6.127390457,"NoSignifi"]
[1666,"REACTOME_LRR_FLII_INTERACTING_PROTEIN_1_LRRFIP1_ACTIVATES_TYPE_I_IFN_PRODUCTION",1.514344315,0.032649034,0.205030767,0.130103727,-0.350348435,-6.128739914,"NoSignifi"]
[1665,"REACTOME_ACTIVATION_OF_GENE_EXPRESSION_BY_SREBF_SREBP",1.507749967,0.011733199,0.207347984,0.131783646,-0.258040449,-6.138650243,"NoSignifi"]
[1664,"REACTOME_REGULATION_OF_PTEN_LOCALIZATION",1.505400046,0.032602867,0.208075726,0.132386341,-0.198498619,-6.142171399,"NoSignifi"]
[1663,"REACTOME_SIGNALING_BY_FGFR1_IN_DISEASE",1.504864617,0.013225208,0.208181824,0.132523963,-0.221779976,-6.142972927,"NoSignifi"]
[1662,"KEGG_PORPHYRIN_AND_CHLOROPHYLL_METABOLISM",1.501167194,0.015232132,0.209457846,0.133477348,-0.115578196,-6.148500145,"NoSignifi"]
[1661,"REACTOME_VITAMIN_B1_THIAMIN_METABOLISM",1.500605132,0.011281076,0.209575232,0.13362274,0.464298962,-6.149339174,"NoSignifi"]
[1660,"REACTOME_DNA_DOUBLE_STRAND_BREAK_RESPONSE",1.49807191,0.014243693,0.210494178,0.134279547,-0.189899524,-6.153116801,"NoSignifi"]
[1659,"BIOCARTA_CCR3_PATHWAY",1.497507775,0.020486467,0.210612797,0.134426154,-0.228044655,-6.153957193,"NoSignifi"]
[1658,"REACTOME_ESTROGEN_DEPENDENT_NUCLEAR_EVENTS_DOWNSTREAM_OF_ESR_MEMBRANE_SIGNALING",1.49531349,0.014997054,0.211396528,0.134997581,-0.229143987,-6.15722301,"NoSignifi"]
[1657,"WP_P53_TRANSCRIPTIONAL_GENE_NETWORK",1.49400405,0.010361512,0.211708588,0.135339474,-0.147411564,-6.159169613,"NoSignifi"]
[1656,"REACTOME_SYNTHESIS_OF_SUBSTRATES_IN_N_GLYCAN_BIOSYTHESIS",1.493021743,0.008647026,0.211998783,0.135596393,-0.133056718,-6.160628784,"NoSignifi"]
[1655,"PID_PI3KCI_PATHWAY",1.489081401,0.012978922,0.213391235,0.136630764,-0.103693377,-6.166472357,"NoSignifi"]
[1654,"PID_MET_PATHWAY",1.482866912,0.013169916,0.215731451,0.138274487,-0.234020281,-6.175657206,"NoSignifi"]
[1653,"REACTOME_VITAMIN_B5_PANTOTHENATE_METABOLISM",1.479733711,0.015210983,0.216805537,0.139108975,-0.148002798,-6.180273461,"NoSignifi"]
[1652,"REACTOME_MTOR_SIGNALLING",1.478363304,0.015016568,0.217262235,0.139475183,-0.204326311,-6.182289468,"NoSignifi"]
[1651,"REACTOME_RAC1_GTPASE_CYCLE",1.477938884,0.00795675,0.217325117,0.13958875,-0.14105279,-6.182913455,"NoSignifi"]
[1650,"REACTOME_INLB_MEDIATED_ENTRY_OF_LISTERIA_MONOCYTOGENES_INTO_HOST_CELL",1.476632183,0.021962794,0.217755991,0.139938845,-0.216989559,-6.184833458,"NoSignifi"]
[1649,"REACTOME_INTERLEUKIN_1_PROCESSING",1.475834394,0.016381262,0.217974871,0.140152923,-0.163337025,-6.186004858,"NoSignifi"]
[1648,"REACTOME_GABA_RECEPTOR_ACTIVATION",1.475111186,0.011223552,0.218048589,0.140347206,-0.039017298,-6.187066203,"NoSignifi"]
[1647,"WP_FATTY_ACID_BETAOXIDATION",1.473765615,0.013275886,0.218496711,0.140709232,-0.184334684,-6.189039518,"NoSignifi"]
[1646,"REACTOME_TRNA_PROCESSING_IN_THE_NUCLEUS",1.473442646,0.010363156,0.218517522,0.140796234,-0.231693222,-6.189512893,"NoSignifi"]
[1645,"BIOCARTA_GCR_PATHWAY",1.47200103,0.023778359,0.219006537,0.141185083,-0.153085863,-6.191624604,"NoSignifi"]
[1644,"REACTOME_SIGNAL_AMPLIFICATION",1.47019908,0.015777575,0.219647529,0.141672286,-0.122729309,-6.194261242,"NoSignifi"]
[1643,"REACTOME_BUTYRATE_RESPONSE_FACTOR_1_BRF1_BINDS_AND_DESTABILIZES_MRNA",1.457296542,0.017154724,0.224667843,0.145198663,-0.284321075,-6.213046262,"NoSignifi"]
[1642,"BIOCARTA_P35ALZHEIMERS_PATHWAY",1.457244342,0.025574007,0.224667843,0.145213065,-0.22885764,-6.213121926,"NoSignifi"]
[1641,"REACTOME_GLOBAL_GENOME_NUCLEOTIDE_EXCISION_REPAIR_GG_NER",1.45575934,0.012512706,0.22487216,0.14562324,-0.207405568,-6.215273285,"NoSignifi"]
[1640,"WP_MIRNA_REGULATION_OF_P53_PATHWAY_IN_PROSTATE_CANCER",1.45386702,0.01525543,0.22542254,0.146147207,-0.23022718,-6.218011567,"NoSignifi"]
[1639,"KEGG_HEMATOPOIETIC_CELL_LINEAGE",1.453694295,0.007599278,0.22542254,0.146195105,0.183274648,-6.218261332,"NoSignifi"]
[1638,"PID_BETA_CATENIN_NUC_PATHWAY",1.453560057,0.013240425,0.22542254,0.146232338,-0.200682887,-6.218455423,"NoSignifi"]
[1637,"REACTOME_ACTIVATION_OF_SMO",1.451868059,0.018313575,0.226029598,0.146702269,-0.095833834,-6.220900303,"NoSignifi"]
[1636,"WP_ECTODERM_DIFFERENTIATION",1.447436654,0.006900421,0.227344432,0.147938512,-0.136561743,-6.227290068,"NoSignifi"]
[1635,"REACTOME_PROTEIN_METHYLATION",1.446554487,0.025795281,0.227606276,0.148185561,-0.142527197,-6.228559763,"NoSignifi"]
[1634,"BIOCARTA_GH_PATHWAY",1.445235993,0.011876073,0.228056336,0.14855539,-0.224677514,-6.230456019,"NoSignifi"]
[1633,"REACTOME_G2_M_DNA_DAMAGE_CHECKPOINT",1.4414612,0.010099215,0.22945048,0.149618097,-0.157263599,-6.235875381,"NoSignifi"]
[1632,"REACTOME_MATURATION_OF_SARS_COV_1_SPIKE_PROTEIN",1.437810393,0.028032272,0.230796718,0.150651411,-0.264717128,-6.241103288,"NoSignifi"]
[1631,"REACTOME_DNA_DAMAGE_RECOGNITION_IN_GG_NER",1.437441561,0.016665038,0.230837998,0.150756106,-0.239154338,-6.241630715,"NoSignifi"]
[1630,"WP_BDNFTRKB_SIGNALING",1.432109272,0.012650532,0.233044945,0.152275916,-0.202327246,-6.249240756,"NoSignifi"]
[1629,"BIOCARTA_IGF1R_PATHWAY",1.428493584,0.01558304,0.234511355,0.153313082,-0.286624721,-6.254384873,"NoSignifi"]
[1628,"BIOCARTA_CLASSIC_PATHWAY",1.426125444,0.021879022,0.235433589,0.153995294,0.075654437,-6.257747043,"NoSignifi"]
[1627,"REACTOME_LISTERIA_MONOCYTOGENES_ENTRY_INTO_HOST_CELLS",1.42465448,0.019063814,0.235961711,0.15442021,-0.203073945,-6.259832645,"NoSignifi"]
[1626,"WP_REGULATION_OF_SISTER_CHROMATID_SEPARATION_AT_THE_METAPHASEANAPHASE_TRANSITION",1.423569031,0.018230921,0.236277829,0.154734334,-0.14047735,-6.261370269,"NoSignifi"]
[1625,"REACTOME_FORMATION_OF_ATP_BY_CHEMIOSMOTIC_COUPLING",1.423389796,0.029357035,0.236277829,0.154786251,-0.143900791,-6.261624055,"NoSignifi"]
[1624,"REACTOME_FC_EPSILON_RECEPTOR_FCERI_SIGNALING",1.4229786,0.015113261,0.236338207,0.154905406,-0.160466534,-6.262206168,"NoSignifi"]
[1623,"REACTOME_TRANSCRIPTION_OF_E2F_TARGETS_UNDER_NEGATIVE_CONTROL_BY_P107_RBL1_AND_P130_RBL2_IN_COMPLEX_WITH_HDAC1",1.422446078,0.01525935,0.236452292,0.155059823,-0.150547207,-6.262959787,"NoSignifi"]
[1622,"BIOCARTA_ARAP_PATHWAY",1.417251403,0.01861483,0.238353129,0.156572274,-0.232261193,-6.270296467,"NoSignifi"]
[1621,"BIOCARTA_PLATELETAPP_PATHWAY",1.41698116,0.023790747,0.238353129,0.156651262,-0.047776111,-6.270677411,"NoSignifi"]
[1620,"BIOCARTA_VDR_PATHWAY",1.416787963,0.016864222,0.238353129,0.156707749,-0.280870489,-6.270949704,"NoSignifi"]
[1619,"REACTOME_GABA_B_RECEPTOR_ACTIVATION",1.415809286,0.012108864,0.238666451,0.156994132,-0.065951744,-6.272328486,"NoSignifi"]
[1618,"WP_NEURAL_CREST_CELL_MIGRATION_DURING_DEVELOPMENT",1.414389195,0.015719564,0.239176788,0.157410389,-0.126101391,-6.2743274509999996,"NoSignifi"]
[1617,"REACTOME_P38MAPK_EVENTS",1.412400286,0.017420481,0.23994195,0.157994783,-0.207425533,-6.277123737,"NoSignifi"]
[1616,"REACTOME_STIMULI_SENSING_CHANNELS",1.410076337,0.005992334,0.240658107,0.158679704,0.057885104,-6.280386096,"NoSignifi"]
[1615,"REACTOME_COMPETING_ENDOGENOUS_RNAS_CERNAS_REGULATE_PTEN_TRANSLATION",1.409975332,0.023237112,0.240658107,0.158709523,-0.220182145,-6.280527765,"NoSignifi"]
[1614,"REACTOME_HEMOSTASIS",1.406391115,0.007074322,0.242088895,0.15977043,-0.078554721,-6.285548416,"NoSignifi"]
[1613,"REACTOME_RORA_ACTIVATES_GENE_EXPRESSION",1.406236961,0.016504652,0.242088895,0.159816178,-0.292363289,-6.285764064,"NoSignifi"]
[1612,"REACTOME_RUNX1_REGULATES_TRANSCRIPTION_OF_GENES_INVOLVED_IN_DIFFERENTIATION_OF_HSCS",1.404876329,0.019260235,0.242577455,0.160220407,-0.14677876,-6.287666444,"NoSignifi"]
[1611,"BIOCARTA_P38MAPK_PATHWAY",1.403301707,0.013298735,0.24279194,0.160689176,-0.256698199,-6.289865723,"NoSignifi"]
[1610,"REACTOME_EUKARYOTIC_TRANSLATION_INITIATION",1.401327077,0.036014665,0.243558414,0.161278492,-0.152490216,-6.292620215,"NoSignifi"]
[1609,"WP_7Q1123_COPY_NUMBER_VARIATION_SYNDROME",1.394956218,0.011923832,0.246071104,0.163190974,-0.132548833,-6.301480796,"NoSignifi"]
[1608,"REACTOME_INFLUENZA_INFECTION",1.391451398,0.029334012,0.24754281,0.164250365,-0.145906178,-6.306338115,"NoSignifi"]
[1607,"REACTOME_TRANSPORT_TO_THE_GOLGI_AND_SUBSEQUENT_MODIFICATION",1.386171792,0.010087055,0.249582584,0.165855991,-0.171021543,-6.313632083,"NoSignifi"]
[1606,"REACTOME_APOPTOSIS_INDUCED_DNA_FRAGMENTATION",1.384320031,0.026299934,0.25030736,0.166421936,-0.278495099,-6.316183802,"NoSignifi"]
[1605,"REACTOME_MODULATION_BY_MTB_OF_HOST_IMMUNE_SYSTEM",1.379877295,0.038556886,0.25197555,0.167785673,-0.160522449,-6.322291997,"NoSignifi"]
[1604,"REACTOME_RUNX1_REGULATES_TRANSCRIPTION_OF_GENES_INVOLVED_IN_DIFFERENTIATION_OF_KERATINOCYTES",1.379092274,0.021865947,0.252211165,0.168027513,-0.236635553,-6.323369263,"NoSignifi"]
[1603,"WP_SRF_AND_MIRS_IN_SMOOTH_MUSCLE_DIFFERENTIATION_AND_PROLIFERATION",1.377478864,0.022170917,0.252702948,0.168525374,-0.227163628,-6.325581387,"NoSignifi"]
[1602,"REACTOME_PRE_NOTCH_EXPRESSION_AND_PROCESSING",1.37592909,0.011825453,0.253293681,0.169004642,-0.181869353,-6.327703828,"NoSignifi"]
[1601,"REACTOME_ACTIVATED_TAK1_MEDIATES_P38_MAPK_ACTIVATION",1.373061748,0.017156745,0.254369884,0.169894065,-0.167233168,-6.331624412,"NoSignifi"]
[1600,"KEGG_VASOPRESSIN_REGULATED_WATER_REABSORPTION",1.369292922,0.012997994,0.255870148,0.171068455,-0.255096116,-6.336765201,"NoSignifi"]
[1599,"REACTOME_AQUAPORIN_MEDIATED_TRANSPORT",1.368266091,0.010218988,0.256221223,0.171389474,-0.063901253,-6.338163384,"NoSignifi"]
[1598,"WP_IL17_SIGNALING_PATHWAY",1.367534555,0.01268042,0.256434413,0.17161845,-0.189341355,-6.33915884,"NoSignifi"]
[1597,"REACTOME_HDACS_DEACETYLATE_HISTONES",1.367098168,0.014455379,0.25650958,0.171755152,-0.294573152,-6.339752413,"NoSignifi"]
[1596,"REACTOME_COPI_DEPENDENT_GOLGI_TO_ER_RETROGRADE_TRAFFIC",1.364313899,0.010545986,0.257685413,0.172629264,-0.104837552,-6.343535112,"NoSignifi"]
[1595,"WP_ENDOTHELIN_PATHWAYS",1.362960212,0.013990537,0.258062398,0.173055452,-0.124782865,-6.345371447,"NoSignifi"]
[1594,"BIOCARTA_ARENRF2_PATHWAY",1.360230094,0.015488294,0.259087155,0.17391738,-0.217137164,-6.349069435,"NoSignifi"]
[1593,"REACTOME_SIGNALING_BY_ROBO_RECEPTORS",1.35923008,0.025092343,0.259313286,0.174233897,-0.156561595,-6.350422117,"NoSignifi"]
[1592,"WP_ONCOSTATIN_M_SIGNALING_PATHWAY",1.35919864,0.012795324,0.259313286,0.174243855,-0.220426003,-6.350464629,"NoSignifi"]
[1591,"REACTOME_SARS_COV_1_INFECTION",1.354879421,0.014163193,0.261224324,0.175615948,-0.158873505,-6.35629554,"NoSignifi"]
[1590,"REACTOME_DEGRADATION_OF_AXIN",1.353031588,0.021533843,0.261969886,0.17620541,-0.188426215,-6.358784443,"NoSignifi"]
[1589,"REACTOME_E3_UBIQUITIN_LIGASES_UBIQUITINATE_TARGET_PROTEINS",1.352439127,0.016272296,0.262120079,0.176394718,-0.206616838,-6.359581729,"NoSignifi"]
[1588,"WP_HAIR_FOLLICLE_DEVELOPMENT_ORGANOGENESIS_PART_2_OF_3",1.34608785,0.013362834,0.264884785,0.178433671,-0.182208356,-6.368106867,"NoSignifi"]
[1587,"REACTOME_PEXOPHAGY",1.338011842,0.026729243,0.268502592,0.181051596,-0.197251445,-6.378889219,"NoSignifi"]
[1586,"REACTOME_ALPHA_PROTEIN_KINASE_1_SIGNALING_PATHWAY",1.334260003,0.026776868,0.270185609,0.182277459,-0.135996361,-6.3838763,"NoSignifi"]
[1585,"REACTOME_CELLULAR_RESPONSE_TO_STARVATION",1.332260318,0.029045224,0.270887326,0.18293334,-0.132980756,-6.386528646,"NoSignifi"]
[1584,"WP_NOVEL_INTRACELLULAR_COMPONENTS_OF_RIGILIKE_RECEPTOR_RLR_PATHWAY",1.325492499,0.00923366,0.274056937,0.185166122,-0.169703388,-6.395475893,"NoSignifi"]
[1583,"REACTOME_POTENTIAL_THERAPEUTICS_FOR_SARS",1.317557718,0.0125583,0.277554231,0.187809515,-0.185732534,-6.405907972,"NoSignifi"]
[1582,"PID_INSULIN_PATHWAY",1.316390763,0.010862409,0.277855605,0.188200614,-0.287668487,-6.407436927,"NoSignifi"]
[1581,"REACTOME_P75_NTR_RECEPTOR_MEDIATED_SIGNALLING",1.315129104,0.0091098,0.278204191,0.188624128,-0.140559302,-6.409088442,"NoSignifi"]
[1580,"REACTOME_ANCHORING_OF_THE_BASAL_BODY_TO_THE_PLASMA_MEMBRANE",1.314670039,0.008946887,0.278293483,0.188778402,-0.139308857,-6.409688967,"NoSignifi"]
[1579,"WP_OSTEOCLAST_SIGNALING",1.313769188,0.01504045,0.278601844,0.189081413,-0.128762904,-6.410866806,"NoSignifi"]
[1578,"REACTOME_RESOLUTION_OF_AP_SITES_VIA_THE_MULTIPLE_NUCLEOTIDE_PATCH_REPLACEMENT_PATHWAY",1.313359027,0.013515508,0.278667003,0.189219494,-0.223895968,-6.411402814,"NoSignifi"]
[1577,"PID_TCR_PATHWAY",1.310913702,0.008068746,0.27956371,0.190044259,-0.078588921,-6.414594952,"NoSignifi"]
[1576,"REACTOME_POLYMERASE_SWITCHING",1.307313768,0.016590099,0.281040057,0.19126327,-0.123562805,-6.419283518,"NoSignifi"]
[1575,"REACTOME_PIWI_INTERACTING_RNA_PIRNA_BIOGENESIS",1.307193402,0.016335325,0.281040057,0.191304128,-0.153214181,-6.41944006,"NoSignifi"]
[1574,"WP_DEGRADATION_PATHWAY_OF_SPHINGOLIPIDS_INCLUDING_DISEASES",1.304957443,0.01774851,0.281777378,0.192064282,-0.174854122,-6.422345433,"NoSignifi"]
[1573,"REACTOME_ACTIVATION_OF_RAS_IN_B_CELLS",1.302834147,0.020489018,0.282059526,0.19278819,-0.142060038,-6.425099818,"NoSignifi"]
[1572,"REACTOME_BUDDING_AND_MATURATION_OF_HIV_VIRION",1.302365917,0.018411566,0.282059526,0.192948096,-0.184357852,-6.425706612,"NoSignifi"]
[1571,"REACTOME_ATF4_ACTIVATES_GENES_IN_RESPONSE_TO_ENDOPLASMIC_RETICULUM_STRESS",1.30186778,0.013914085,0.282169439,0.193118323,-0.257376135,-6.426351926,"NoSignifi"]
[1570,"REACTOME_MITOCHONDRIAL_FATTY_ACID_BETA_OXIDATION_OF_UNSATURATED_FATTY_ACIDS",1.300947658,0.023131567,0.282211818,0.193433044,-0.305216941,-6.427543254,"NoSignifi"]
[1569,"BIOCARTA_BAD_PATHWAY",1.30078497,0.014494256,0.282211818,0.193488729,-0.194813382,-6.427753808,"NoSignifi"]
[1568,"REACTOME_SYNTHESIS_OF_IP2_IP_AND_INS_IN_THE_CYTOSOL",1.300782773,0.010661574,0.282211818,0.193489481,-0.031913323,-6.42775665,"NoSignifi"]
[1567,"REACTOME_NS1_MEDIATED_EFFECTS_ON_HOST_PATHWAYS",1.300671607,0.010721548,0.282211818,0.193527538,-0.229298504,-6.427900508,"NoSignifi"]
[1566,"BIOCARTA_LECTIN_PATHWAY",1.298402606,0.018995732,0.283068251,0.194305522,0.053209177,-6.430834081,"NoSignifi"]
[1565,"WP_DNA_REPLICATION",1.293488537,0.0102032,0.284975007,0.195998304,-0.082260587,-6.437169915,"NoSignifi"]
[1564,"BIOCARTA_PROTEASOME_PATHWAY",1.289328192,0.024825587,0.286790118,0.197439879,-0.203960897,-6.442515207,"NoSignifi"]
[1563,"REACTOME_GENE_AND_PROTEIN_EXPRESSION_BY_JAK_STAT_SIGNALING_AFTER_INTERLEUKIN_12_STIMULATION",1.287690812,0.02039634,0.287476673,0.198009362,-0.161609016,-6.444614231,"NoSignifi"]
[1562,"WP_GASTRIN_SIGNALING_PATHWAY",1.286764857,0.011182622,0.28780427,0.198331942,-0.207170732,-6.445800071,"NoSignifi"]
[1561,"REACTOME_HYDROLYSIS_OF_LPC",1.282435747,0.013173733,0.289738648,0.199845202,0.04077912,-6.451332924,"NoSignifi"]
[1560,"KEGG_PROPANOATE_METABOLISM",1.280874785,0.011998036,0.29005218,0.200392908,-0.178141828,-6.453323358,"NoSignifi"]
[1559,"BIOCARTA_CDC42RAC_PATHWAY",1.279480659,0.024585185,0.290512241,0.200883001,-0.18149116,-6.455099008,"NoSignifi"]
[1558,"WP_QUERCETIN_AND_NFKB_AP1_INDUCED_APOPTOSIS",1.275073098,0.017832307,0.292476406,0.2024382,-0.143000315,-6.460700066,"NoSignifi"]
[1557,"REACTOME_RNA_POLYMERASE_III_TRANSCRIPTION_TERMINATION",1.274279152,0.017533016,0.292740039,0.202719273,-0.161764167,-6.461706949,"NoSignifi"]
[1556,"REACTOME_FGFR1B_LIGAND_BINDING_AND_ACTIVATION",1.269067396,0.020926075,0.295127553,0.204571406,0.062748471,-6.46830096,"NoSignifi"]
[1555,"REACTOME_CELLULAR_RESPONSE_TO_CHEMICAL_STRESS",1.266709148,0.014611204,0.296198495,0.205413507,-0.152241718,-6.471275794,"NoSignifi"]
[1554,"REACTOME_TRISTETRAPROLIN_TTP_ZFP36_BINDS_AND_DESTABILIZES_MRNA",1.265732926,0.014731007,0.29655819,0.20576284,-0.289682555,-6.472505641,"NoSignifi"]
[1553,"REACTOME_MATURATION_OF_SARS_COV_1_NUCLEOPROTEIN",1.263074197,0.018588308,0.297788014,0.206716436,-0.234104214,-6.475850317,"NoSignifi"]
[1552,"REACTOME_FOXO_MEDIATED_TRANSCRIPTION_OF_CELL_DEATH_GENES",1.26063709,0.015647065,0.298616611,0.20759336,-0.26620436,-6.478910024,"NoSignifi"]
[1551,"REACTOME_SIGNALING_BY_PTK6",1.252232159,0.012397326,0.30255697,0.210638349,-0.138281282,-6.489416881,"NoSignifi"]
[1550,"REACTOME_SMALL_INTERFERING_RNA_SIRNA_BIOGENESIS",1.24209968,0.017905461,0.307296566,0.214352033,-0.295343611,-6.501990029,"NoSignifi"]
[1549,"REACTOME_TRANSCRIPTIONAL_REGULATION_BY_RUNX1",1.241267802,0.010509477,0.307588132,0.214659013,-0.170949437,-6.503017755,"NoSignifi"]
[1548,"REACTOME_FBXW7_MUTANTS_AND_NOTCH1_IN_CANCER",1.239776862,0.024211586,0.308228882,0.215209994,-0.239480925,-6.504857988,"NoSignifi"]
[1547,"REACTOME_TICAM1_TRAF6_DEPENDENT_INDUCTION_OF_TAK1_COMPLEX",1.239359914,0.024562006,0.308301104,0.21536426,-0.133986507,-6.505372221,"NoSignifi"]
[1546,"BIOCARTA_EGFR_SMRTE_PATHWAY",1.238570389,0.015251853,0.30857081,0.215656595,-0.261883756,-6.506345492,"NoSignifi"]
[1545,"REACTOME_FOLDING_OF_ACTIN_BY_CCT_TRIC",1.235682523,0.027005245,0.309954892,0.216728311,-0.282980513,-6.509900176,"NoSignifi"]
[1544,"KEGG_UBIQUITIN_MEDIATED_PROTEOLYSIS",1.234968355,0.00978243,0.310185362,0.216993936,-0.225419323,-6.51077797,"NoSignifi"]
[1543,"KEGG_RIG_I_LIKE_RECEPTOR_SIGNALING_PATHWAY",1.232231269,0.008334563,0.311493721,0.21801413,-0.151665507,-6.514137469,"NoSignifi"]
[1542,"WP_THYROID_STIMULATING_HORMONE_TSH_SIGNALING_PATHWAY",1.22688252,0.011392602,0.314054138,0.220017719,-0.204875256,-6.52068104,"NoSignifi"]
[1541,"WP_RANKLRANK_SIGNALING_PATHWAY",1.223846483,0.009895333,0.315231192,0.221160853,-0.213667606,-6.524382633,"NoSignifi"]
[1540,"REACTOME_ACTIVATION_OF_PPARGC1A_PGC_1ALPHA_BY_PHOSPHORYLATION",1.221932295,0.011282825,0.316109849,0.221883774,-0.029135206,-6.526711741,"NoSignifi"]
[1539,"PID_RAC1_REG_PATHWAY",1.220300043,0.009733347,0.316382717,0.222501554,-0.12684671,-6.528694924,"NoSignifi"]
[1538,"WP_COVID19_ADVERSE_OUTCOME_PATHWAY",1.215024958,0.00745377,0.319080817,0.22450651,0.354080551,-6.535086045,"NoSignifi"]
[1537,"BIOCARTA_TNFR2_PATHWAY",1.214081846,0.014086129,0.319439292,0.224866325,-0.189801,-6.536225776,"NoSignifi"]
[1536,"PID_RETINOIC_ACID_PATHWAY",1.212778694,0.010049072,0.319993427,0.225364182,-0.272801235,-6.537799153,"NoSignifi"]
[1535,"WP_WNT_SIGNALING_IN_KIDNEY_DISEASE",1.210291194,0.008447409,0.320953945,0.226316692,-0.025443346,-6.540797785,"NoSignifi"]
[1534,"REACTOME_INTERLEUKIN_12_FAMILY_SIGNALING",1.210165346,0.01662662,0.320953945,0.226364958,-0.124463996,-6.540949329,"NoSignifi"]
[1533,"REACTOME_POSITIVE_EPIGENETIC_REGULATION_OF_RRNA_EXPRESSION",1.208123702,0.012719069,0.321818529,0.227149006,-0.186035064,-6.543405641,"NoSignifi"]
[1532,"REACTOME_TRANSCRIPTIONAL_REGULATION_BY_RUNX3",1.208007959,0.01387935,0.321818529,0.227193512,-0.167412444,-6.543544767,"NoSignifi"]
[1531,"REACTOME_REGULATION_OF_HMOX1_EXPRESSION_AND_ACTIVITY",1.203408965,0.018802217,0.323561643,0.228966996,-0.171170023,-6.549062141,"NoSignifi"]
[1530,"REACTOME_DEFECTIVE_LFNG_CAUSES_SCDO3",1.200918412,0.021729009,0.324461351,0.22993152,-0.21446404,-6.552041265,"NoSignifi"]
[1529,"REACTOME_THROMBIN_SIGNALLING_THROUGH_PROTEINASE_ACTIVATED_RECEPTORS_PARS",1.200000621,0.012565777,0.324655334,0.230287684,-0.128265189,-6.553137545,"NoSignifi"]
[1528,"REACTOME_SIGNALING_BY_PDGFRA_TRANSMEMBRANE_JUXTAMEMBRANE_AND_KINASE_DOMAIN_MUTANTS",1.197891783,0.01629841,0.325502033,0.23110754,-0.27152322,-6.555653333,"NoSignifi"]
[1527,"REACTOME_CYTOSOLIC_SENSORS_OF_PATHOGEN_ASSOCIATED_DNA",1.196973752,0.011529523,0.325851047,0.231465092,-0.155909079,-6.556747139,"NoSignifi"]
[1526,"REACTOME_SYNTHESIS_OF_PIPS_AT_THE_LATE_ENDOSOME_MEMBRANE",1.196186512,0.014312695,0.326128491,0.231772016,-0.223239212,-6.557684443,"NoSignifi"]
[1525,"REACTOME_DDX58_IFIH1_MEDIATED_INDUCTION_OF_INTERFERON_ALPHA_BETA",1.194957258,0.01166653,0.326648859,0.232251849,-0.160083015,-6.559146789,"NoSignifi"]
[1524,"REACTOME_RHOQ_GTPASE_CYCLE",1.192204223,0.010095637,0.327853253,0.233329041,-0.217831156,-6.562416411,"NoSignifi"]
[1523,"REACTOME_NRAGE_SIGNALS_DEATH_THROUGH_JNK",1.188409833,0.007488583,0.329635495,0.234819492,-0.124479332,-6.566910447,"NoSignifi"]
[1522,"REACTOME_CD209_DC_SIGN_SIGNALING",1.185182764,0.012771259,0.33110927,0.236092396,-0.224986363,-6.570721299,"NoSignifi"]
[1521,"PID_KIT_PATHWAY",1.180623838,0.008916484,0.333327987,0.237898958,-0.202390452,-6.576087308,"NoSignifi"]
[1520,"REACTOME_SYNTHESIS_OF_5_EICOSATETRAENOIC_ACIDS",1.178022173,0.015648764,0.334462938,0.238934285,0.048628987,-6.579140301,"NoSignifi"]
[1519,"REACTOME_RHOD_GTPASE_CYCLE",1.177367974,0.009541591,0.334670272,0.239195122,-0.224550598,-6.57990693,"NoSignifi"]
[1518,"BIOCARTA_MTOR_PATHWAY",1.169630057,0.016015751,0.338848598,0.242295579,-0.245737845,-6.588942416,"NoSignifi"]
[1517,"PID_IL3_PATHWAY",1.168975409,0.0117401,0.339038951,0.242559177,-0.213765277,-6.589704112,"NoSignifi"]
[1516,"REACTOME_MATURATION_OF_SARS_COV_2_NUCLEOPROTEIN",1.168724954,0.017118412,0.339038951,0.242660078,-0.210261191,-6.589995408,"NoSignifi"]
[1515,"REACTOME_INTERLEUKIN_37_SIGNALING",1.167615747,0.011039058,0.339344416,0.2431073,-0.179335926,-6.591284745,"NoSignifi"]
[1514,"REACTOME_ESTROGEN_BIOSYNTHESIS",1.164850603,0.011353195,0.340443053,0.244224703,0.163636945,-6.594493612,"NoSignifi"]
[1513,"WP_EPO_RECEPTOR_SIGNALING",1.164811286,0.011190727,0.340443053,0.244240617,-0.257341369,-6.594539184,"NoSignifi"]
[1512,"REACTOME_RNA_POLYMERASE_III_TRANSCRIPTION",1.155777891,0.010871435,0.345083742,0.247916343,-0.183754353,-6.604968864,"NoSignifi"]
[1511,"REACTOME_ACTIVATION_OF_RAC1",1.152305052,0.014293931,0.346739865,0.249339714,-0.233972097,-6.608956919,"NoSignifi"]
[1510,"WP_NONHOMOLOGOUS_END_JOINING",1.146058096,0.014970466,0.349970592,0.251914449,-0.048720401,-6.616100478,"NoSignifi"]
[1509,"REACTOME_RAB_GERANYLGERANYLATION",1.146017396,0.009586324,0.349970592,0.251931284,-0.143216855,-6.616146893,"NoSignifi"]
[1508,"BIOCARTA_PRC2_PATHWAY",1.145811303,0.015508558,0.349970592,0.252016546,-0.254901037,-6.616381896,"NoSignifi"]
[1507,"WP_IL1_SIGNALING_PATHWAY",1.143681309,0.008639029,0.351031736,0.252898917,-0.234866778,-6.618808213,"NoSignifi"]
[1506,"REACTOME_LIGAND_RECEPTOR_INTERACTIONS",1.140485811,0.022712944,0.352380545,0.254226719,-0.117774677,-6.622439811,"NoSignifi"]
[1505,"REACTOME_TRANSLATION",1.129972506,0.018891074,0.35781495,0.258629465,-0.154733458,-6.634316289,"NoSignifi"]
[1504,"REACTOME_REELIN_SIGNALLING_PATHWAY",1.12770612,0.026228398,0.358970308,0.259585467,-0.161848156,-6.636862146,"NoSignifi"]
[1503,"BIOCARTA_LONGEVITY_PATHWAY",1.123022233,0.01424485,0.361208494,0.261568967,-0.269523576,-6.642107436,"NoSignifi"]
[1502,"REACTOME_ABC_TRANSPORTER_DISORDERS",1.121767787,0.015764129,0.361698381,0.262101966,-0.16139631,-6.643508536,"NoSignifi"]
[1501,"REACTOME_SIGNALING_BY_BMP",1.12143925,0.01237245,0.361698381,0.262241682,-0.190560149,-6.643875223,"NoSignifi"]
[1500,"REACTOME_RUNX3_REGULATES_YAP1_MEDIATED_TRANSCRIPTION",1.121327556,0.018649078,0.361698381,0.262289193,-0.145369255,-6.643999863,"NoSignifi"]
[1499,"REACTOME_PECAM1_INTERACTIONS",1.114652453,0.014629105,0.365289496,0.265139395,-0.146935354,-6.651426113,"NoSignifi"]
[1498,"KEGG_COLORECTAL_CANCER",1.113509075,0.009092516,0.365795314,0.26562974,-0.207836081,-6.652693712,"NoSignifi"]
[1497,"REACTOME_PROGRAMMED_CELL_DEATH",1.110605485,0.01065816,0.367343579,0.266877771,-0.159486528,-6.655906923,"NoSignifi"]
[1496,"BIOCARTA_DSP_PATHWAY",1.109483261,0.016579359,0.367790456,0.267361208,-0.245571153,-6.657146569,"NoSignifi"]
[1495,"WP_CHROMOSOMAL_AND_MICROSATELLITE_INSTABILITY_IN_COLORECTAL_CANCER",1.105532193,0.00883053,0.369844021,0.269068065,-0.219235999,-6.66150109,"NoSignifi"]
[1494,"REACTOME_MOLYBDENUM_COFACTOR_BIOSYNTHESIS",1.10483661,0.021034969,0.370086783,0.269369329,-0.113735075,-6.662266094,"NoSignifi"]
[1493,"REACTOME_PLASMA_LIPOPROTEIN_CLEARANCE",1.104400014,0.011219146,0.370175444,0.269558542,-0.12425375,-6.662746018,"NoSignifi"]
[1492,"WP_MIR124_PREDICTED_INTERACTIONS_WITH_CELL_CYCLE_AND_DIFFERENTIATION",1.103158922,0.017802359,0.37074328,0.270096906,-0.261329812,-6.664109241,"NoSignifi"]
[1491,"REACTOME_BASE_EXCISION_REPAIR",1.10229108,0.008311649,0.371089053,0.270473799,-0.182234904,-6.665061575,"NoSignifi"]
[1490,"REACTOME_HEDGEHOG_ON_STATE",1.10151104,0.014171255,0.371382637,0.270812869,-0.157960545,-6.66591692,"NoSignifi"]
[1489,"REACTOME_PINK1_PRKN_MEDIATED_MITOPHAGY",1.100687687,0.017196456,0.37170219,0.271171082,-0.20352523,-6.666819104,"NoSignifi"]
[1488,"REACTOME_ASPARAGINE_N_LINKED_GLYCOSYLATION",1.100093596,0.00723084,0.371885066,0.271429753,-0.162984684,-6.667469657,"NoSignifi"]
[1487,"BIOCARTA_CARM_ER_PATHWAY",1.098386348,0.010630104,0.372732807,0.27217404,-0.26552686,-6.669337207,"NoSignifi"]
[1486,"REACTOME_SIGNALING_BY_LEPTIN",1.097867294,0.014145031,0.372871087,0.272400602,-0.194270141,-6.669904424,"NoSignifi"]
[1485,"WP_WNT_SIGNALING_PATHWAY_AND_PLURIPOTENCY",1.097145995,0.006468047,0.373130316,0.272715657,-0.132365102,-6.670692206,"NoSignifi"]
[1484,"REACTOME_LEISHMANIA_INFECTION",1.096288191,0.007050255,0.37347129,0.27309066,-0.109162433,-6.671628403,"NoSignifi"]
[1483,"SA_PROGRAMMED_CELL_DEATH",1.090696319,0.01344634,0.376306255,0.275543887,-0.167378122,-6.677713381,"NoSignifi"]
[1482,"WP_FATTY_ACID_BIOSYNTHESIS",1.090260242,0.010333289,0.376395254,0.275735829,-0.190667271,-6.678186605,"NoSignifi"]
[1481,"REACTOME_ANTIGEN_ACTIVATES_B_CELL_RECEPTOR_BCR_LEADING_TO_GENERATION_OF_SECOND_MESSENGERS",1.088449117,0.010754969,0.377311311,0.276533989,-0.127912269,-6.680149992,"NoSignifi"]
[1480,"REACTOME_CALCINEURIN_ACTIVATES_NFAT",1.08669127,0.019149214,0.378022916,0.277310175,-0.219373062,-6.682052505,"NoSignifi"]
[1479,"REACTOME_HEDGEHOG_LIGAND_BIOGENESIS",1.085680628,0.016483351,0.37845839,0.277757101,-0.172089752,-6.683144928,"NoSignifi"]
[1478,"REACTOME_IRAK2_MEDIATED_ACTIVATION_OF_TAK1_COMPLEX",1.084592559,0.02303214,0.378767099,0.278238815,-0.142222314,-6.68431991,"NoSignifi"]
[1477,"REACTOME_ESTROGEN_DEPENDENT_GENE_EXPRESSION",1.083589997,0.008966221,0.379198144,0.278683177,-0.202067402,-6.685401513,"NoSignifi"]
[1476,"BIOCARTA_HDAC_PATHWAY",1.080502894,0.012375614,0.380554912,0.280054494,-0.198244248,-6.688725725,"NoSignifi"]
[1475,"REACTOME_ADAPTIVE_IMMUNE_SYSTEM",1.079705677,0.006298892,0.380559463,0.280409369,-0.133258586,-6.689582634,"NoSignifi"]
[1474,"PID_RANBP2_PATHWAY",1.079704215,0.015702647,0.380559463,0.28041002,-0.271808185,-6.689584205,"NoSignifi"]
[1473,"REACTOME_METABOLISM_OF_RNA",1.079319804,0.01151733,0.380559946,0.280581247,-0.172048449,-6.689997173,"NoSignifi"]
[1472,"REACTOME_METABOLISM_OF_FAT_SOLUBLE_VITAMINS",1.075931747,0.007771856,0.382128471,0.282093452,-0.082609138,-6.693630568,"NoSignifi"]
[1471,"REACTOME_REGULATION_OF_TP53_ACTIVITY_THROUGH_METHYLATION",1.075863845,0.013919415,0.382128471,0.282123815,-0.246058213,-6.69370327,"NoSignifi"]
[1470,"REACTOME_CAMK_IV_MEDIATED_PHOSPHORYLATION_OF_CREB",1.072737406,0.014326986,0.383500457,0.283524252,-0.164240605,-6.697045769,"NoSignifi"]
[1469,"BIOCARTA_ARF_PATHWAY",1.069306593,0.013236453,0.385235442,0.285066442,-0.198097625,-6.700702497,"NoSignifi"]
[1468,"WP_22Q112_COPY_NUMBER_VARIATION_SYNDROME",1.066338633,0.005839203,0.386868462,0.286405146,-0.095577078,-6.703856454,"NoSignifi"]
[1467,"REACTOME_CYTOPROTECTION_BY_HMOX1",1.065692958,0.012658594,0.387010337,0.286696941,-0.162771047,-6.704541433,"NoSignifi"]
[1466,"REACTOME_MISCELLANEOUS_TRANSPORT_AND_BINDING_EVENTS",1.06504056,0.009586665,0.38713275,0.286991978,-0.124202724,-6.705233123,"NoSignifi"]
[1465,"BIOCARTA_LIS1_PATHWAY",1.062615924,0.013043899,0.388261481,0.288090281,-0.099007899,-6.707800081,"NoSignifi"]
[1464,"KEGG_PROTEASOME",1.059907238,0.018396572,0.38974268,0.289320602,-0.189375914,-6.710660852,"NoSignifi"]
[1463,"PID_TAP63_PATHWAY",1.059545048,0.00939558,0.389787799,0.289485381,-0.201652687,-6.711042824,"NoSignifi"]
[1462,"BIOCARTA_NFAT_PATHWAY",1.058368601,0.00953169,0.390332043,0.290021046,-0.156540002,-6.712282631,"NoSignifi"]
[1461,"REACTOME_TRANSLESION_SYNTHESIS_BY_POLH",1.057712296,0.016613511,0.390494237,0.290320167,-0.175979882,-6.712973683,"NoSignifi"]
[1460,"WP_INSULIN_SIGNALING",1.057527111,0.006217295,0.390494237,0.290404606,-0.205134042,-6.713168595,"NoSignifi"]
[1459,"WP_HIJACK_OF_UBIQUITINATION_BY_SARSCOV2",1.054861445,0.018358783,0.391599014,0.291621899,-0.279513451,-6.715970503,"NoSignifi"]
[1458,"REACTOME_DEFECTIVE_CFTR_CAUSES_CYSTIC_FIBROSIS",1.053188,0.016378511,0.392450044,0.29238784,-0.176278917,-6.717725869,"NoSignifi"]
[1457,"REACTOME_SIGNALING_BY_ALK",1.049700489,0.009280072,0.394241931,0.293988426,-0.157215283,-6.72137516,"NoSignifi"]
[1456,"REACTOME_COENZYME_A_BIOSYNTHESIS",1.048935203,0.015231724,0.39441041,0.294340437,-0.21832448,-6.722174329,"NoSignifi"]
[1455,"REACTOME_RAC3_GTPASE_CYCLE",1.048849781,0.007545765,0.39441041,0.294379747,-0.157082216,-6.722263496,"NoSignifi"]
[1454,"REACTOME_DIGESTION",1.045668608,0.008450638,0.396017702,0.295846165,0.348556288,-6.725579005,"NoSignifi"]
[1453,"BIOCARTA_AKAPCENTROSOME_PATHWAY",1.043212036,0.012776623,0.396936286,0.296981908,-0.233720735,-6.72813243,"NoSignifi"]
[1452,"REACTOME_APOPTOTIC_CLEAVAGE_OF_CELLULAR_PROTEINS",1.037384994,0.011057119,0.399897708,0.299687572,-0.190384846,-6.734165218,"NoSignifi"]
[1451,"WP_TARGET_OF_RAPAMYCIN_TOR_SIGNALING",1.036570899,0.010004961,0.400044268,0.300066886,-0.226681873,-6.73500537,"NoSignifi"]
[1450,"REACTOME_CLEC7A_INFLAMMASOME_PATHWAY",1.032519521,0.016152689,0.402206019,0.301959319,-0.284656084,-6.739176627,"NoSignifi"]
[1449,"REACTOME_SIGNALING_BY_WNT_IN_CANCER",1.031508665,0.010965183,0.402655959,0.302432734,-0.213768506,-6.74021485,"NoSignifi"]
[1448,"WP_VASOPRESSINREGULATED_WATER_REABSORPTION",1.026513179,0.009578487,0.405416857,0.30477953,-0.25193595,-6.745330667,"NoSignifi"]
[1447,"REACTOME_INTERLEUKIN_6_SIGNALING",1.021488547,0.014960498,0.407659744,0.307152188,-0.189763305,-6.750451306,"NoSignifi"]
[1446,"REACTOME_MET_ACTIVATES_RAS_SIGNALING",1.019930091,0.013800191,0.408274735,0.30789058,-0.249777553,-6.75203444,"NoSignifi"]
[1445,"REACTOME_DEGRADATION_OF_DVL",1.017582665,0.016622531,0.40954938,0.309005001,-0.170480772,-6.75441448,"NoSignifi"]
[1444,"REACTOME_MITOCHONDRIAL_PROTEIN_IMPORT",1.017324539,0.010848836,0.40954938,0.309127706,-0.193133655,-6.754675858,"NoSignifi"]
[1443,"REACTOME_MRNA_DECAY_BY_3_TO_5_EXORIBONUCLEASE",1.01627725,0.011356355,0.410026433,0.309625889,-0.288406828,-6.755735663,"NoSignifi"]
[1442,"REACTOME_RESPONSE_TO_ELEVATED_PLATELET_CYTOSOLIC_CA2",1.012646364,0.009519843,0.41196567,0.311357163,-0.121527068,-6.759401492,"NoSignifi"]
[1441,"WP_CYSTEINE_AND_METHIONINE_CATABOLISM",1.011674421,0.009119564,0.412320307,0.311821685,-0.051164768,-6.760380566,"NoSignifi"]
[1440,"BIOCARTA_CERAMIDE_PATHWAY",1.010939124,0.010442205,0.412473606,0.312173411,-0.270819876,-6.761120633,"NoSignifi"]
[1439,"REACTOME_RRNA_PROCESSING",1.010659161,0.017800686,0.412473606,0.312307399,-0.142549543,-6.761402271,"NoSignifi"]
[1438,"KEGG_GAP_JUNCTION",1.001338931,0.007788919,0.418021497,0.316789615,-0.175847848,-6.770733786,"NoSignifi"]
[1437,"REACTOME_METABOLISM_OF_POLYAMINES",0.998762804,0.014832766,0.419264205,0.31803592,-0.183204901,-6.773297797,"NoSignifi"]
[1436,"REACTOME_CELLULAR_RESPONSES_TO_STIMULI",0.994930056,0.010460667,0.421184722,0.319896109,-0.156315397,-6.777100309,"NoSignifi"]
[1435,"REACTOME_FREE_FATTY_ACIDS_REGULATE_INSULIN_SECRETION",0.993034254,0.013281904,0.422163607,0.320818846,-0.155427686,-6.778975757,"NoSignifi"]
[1434,"REACTOME_ANTIGEN_PROCESSING_UBIQUITINATION_PROTEASOME_DEGRADATION",0.990267586,0.007186353,0.423613156,0.322168577,-0.186053316,-6.781706309,"NoSignifi"]
[1433,"PID_MYC_PATHWAY",0.987102395,0.009934718,0.425084731,0.323717271,-0.278149833,-6.784820847,"NoSignifi"]
[1432,"REACTOME_TRNA_AMINOACYLATION",0.981913403,0.010087177,0.427773576,0.326266673,-0.143443105,-6.789905249,"NoSignifi"]
[1431,"REACTOME_NEUTROPHIL_DEGRANULATION",0.981762024,0.007016097,0.427773576,0.326341243,-0.14071653,-6.790053175,"NoSignifi"]
[1430,"BIOCARTA_AKAP13_PATHWAY",0.978054652,0.013010231,0.429907679,0.328170958,-0.184930742,-6.793668866,"NoSignifi"]
[1429,"REACTOME_ACTIVATION_OF_THE_MRNA_UPON_BINDING_OF_THE_CAP_BINDING_COMPLEX_AND_EIFS_AND_SUBSEQUENT_BINDING_TO_43S",0.976533214,0.023451224,0.430209099,0.328923764,-0.16343081,-6.795148726,"NoSignifi"]
[1428,"REACTOME_SUMOYLATION_OF_UBIQUITINYLATION_PROTEINS",0.973202943,0.007700957,0.431988826,0.330575484,-0.243632471,-6.798379952,"NoSignifi"]
[1427,"REACTOME_IRAK1_RECRUITS_IKK_COMPLEX",0.972523131,0.016706425,0.432049965,0.330913311,-0.184774688,-6.799038191,"NoSignifi"]
[1426,"REACTOME_RUNX2_REGULATES_GENES_INVOLVED_IN_CELL_MIGRATION",0.970329293,0.012454218,0.433094452,0.332005043,-0.248489913,-6.801159275,"NoSignifi"]
[1425,"REACTOME_DOWNSTREAM_SIGNALING_EVENTS_OF_B_CELL_RECEPTOR_BCR",0.969094314,0.013472474,0.433516537,0.332620637,-0.169311159,-6.802351193,"NoSignifi"]
[1424,"REACTOME_REPRESSION_OF_WNT_TARGET_GENES",0.966781691,0.011665426,0.434573444,0.33377538,-0.196925671,-6.804579102,"NoSignifi"]
[1423,"WP_15Q112_COPY_NUMBER_VARIATION_SYNDROME",0.965082005,0.012898285,0.435365363,0.334625718,-0.23627486,-6.806213136,"NoSignifi"]
[1422,"REACTOME_TP53_REGULATES_TRANSCRIPTION_OF_GENES_INVOLVED_IN_CYTOCHROME_C_RELEASE",0.964741012,0.010931663,0.43539674,0.334796483,-0.13822801,-6.806540612,"NoSignifi"]
[1421,"BIOCARTA_EDG1_PATHWAY",0.955581043,0.011651228,0.440689334,0.339404677,-0.20610269,-6.815294209,"NoSignifi"]
[1420,"REACTOME_NEGATIVE_REGULATION_OF_NOTCH4_SIGNALING",0.954239132,0.015983467,0.44111268,0.340083168,-0.180019608,-6.816569581,"NoSignifi"]
[1419,"REACTOME_ACTIVATION_OF_ANTERIOR_HOX_GENES_IN_HINDBRAIN_DEVELOPMENT_DURING_EARLY_EMBRYOGENESIS",0.950508484,0.007530753,0.443178016,0.34197401,-0.184957076,-6.820105836,"NoSignifi"]
[1418,"REACTOME_OXIDATIVE_STRESS_INDUCED_SENESCENCE",0.94899927,0.008357238,0.443784379,0.342740849,-0.210826473,-6.821532479,"NoSignifi"]
[1417,"REACTOME_ARACHIDONATE_PRODUCTION_FROM_DAG",0.948466674,0.018822231,0.443941506,0.343011726,-0.173297027,-6.822035394,"NoSignifi"]
[1416,"WP_CALCIUM_REGULATION_IN_CARDIAC_CELLS",0.947783303,0.006560886,0.444197959,0.343359487,-0.070804511,-6.82268027,"NoSignifi"]
[1415,"WP_VALPROIC_ACID_PATHWAY",0.94569388,0.014115553,0.445381258,0.344424173,-0.203671423,-6.824649111,"NoSignifi"]
[1414,"BIOCARTA_CFTR_PATHWAY",0.941377544,0.014191843,0.447649099,0.346630272,-0.179809964,-6.828702603,"NoSignifi"]
[1413,"WP_WNT_SIGNALING_PATHWAY",0.939676667,0.00730554,0.448579841,0.347502066,-0.163941367,-6.830294816,"NoSignifi"]
[1412,"WP_THIAMINE_METABOLIC_PATHWAYS",0.938655721,0.012317365,0.448865888,0.348026027,-0.07175634,-6.831249155,"NoSignifi"]
[1411,"REACTOME_DETOXIFICATION_OF_REACTIVE_OXYGEN_SPECIES",0.936129302,0.011749098,0.450149849,0.349324773,-0.134197496,-6.833606294,"NoSignifi"]
[1410,"REACTOME_FCERI_MEDIATED_NF_KB_ACTIVATION",0.9349641,0.012675363,0.450727433,0.349924801,-0.154649352,-6.834691284,"NoSignifi"]
[1409,"WP_MICRORNAS_IN_CARDIOMYOCYTE_HYPERTROPHY",0.934574102,0.006960183,0.450790736,0.350125779,-0.175707974,-6.835054134,"NoSignifi"]
[1408,"REACTOME_APOPTOSIS",0.929348188,0.009269774,0.453873549,0.352825918,-0.159631103,-6.839901666,"NoSignifi"]
[1407,"WP_P38_MAPK_SIGNALING_PATHWAY",0.927074191,0.009158745,0.455030367,0.354004958,-0.24955485,-6.842002535,"NoSignifi"]
[1406,"REACTOME_NEGATIVE_REGULATION_OF_FGFR2_SIGNALING",0.926972544,0.009681546,0.455030367,0.354057719,-0.220033163,-6.842096323,"NoSignifi"]
[1405,"WP_CORTICOTROPINRELEASING_HORMONE_SIGNALING_PATHWAY",0.926727426,0.007757819,0.455030367,0.354184971,-0.172567478,-6.842322448,"NoSignifi"]
[1404,"WP_PROGERIAASSOCIATED_LIPODYSTROPHY",0.92532888,0.010544339,0.455512212,0.354911569,-0.20971906,-6.84361148,"NoSignifi"]
[1403,"REACTOME_HIV_ELONGATION_ARREST_AND_RECOVERY",0.92511976,0.010491888,0.455512212,0.355020296,-0.253397591,-6.843804058,"NoSignifi"]
[1402,"REACTOME_DEGRADATION_OF_GLI1_BY_THE_PROTEASOME",0.924716924,0.014534165,0.455584136,0.3552298,-0.18377299,-6.844174905,"NoSignifi"]
[1401,"WP_INTRAFLAGELLAR_TRANSPORT_PROTEINS_BINDING_TO_DYNEIN",0.922974731,0.01074171,0.456550111,0.356136766,-0.180781483,-6.845776896,"NoSignifi"]
[1400,"BIOCARTA_VITCB_PATHWAY",0.920696137,0.013568017,0.457875897,0.357325178,0.012943942,-6.847867565,"NoSignifi"]
[1399,"REACTOME_DEGRADATION_OF_BETA_CATENIN_BY_THE_DESTRUCTION_COMPLEX",0.920278333,0.011686446,0.457957819,0.357543357,-0.183815594,-6.84825035,"NoSignifi"]
[1398,"REACTOME_MET_INTERACTS_WITH_TNS_PROTEINS",0.917444135,0.019356856,0.459459916,0.3590256,-0.212628195,-6.850842419,"NoSignifi"]
[1397,"WP_CELL_MIGRATION_AND_INVASION_THROUGH_P75NTR",0.915452147,0.010941939,0.460399184,0.360069689,-0.158730352,-6.852659446,"NoSignifi"]
[1396,"WP_TRANSCRIPTION_FACTORS_REGULATE_MIRNAS_RELATED_TO_CARDIAC_HYPERTROPHY",0.913668295,0.014512306,0.461398069,0.361006303,-0.286952538,-6.854283272,"NoSignifi"]
[1395,"REACTOME_FCGR_ACTIVATION",0.913215964,0.007982966,0.461503254,0.361244043,0.263273767,-6.854694521,"NoSignifi"]
[1394,"WP_ENVELOPE_PROTEINS_AND_THEIR_POTENTIAL_ROLES_IN_EDMD_PHYSIOPATHOLOGY",0.912648359,0.008292375,0.461685895,0.361542508,-0.236356872,-6.855210288,"NoSignifi"]
[1393,"WP_APOPTOSISRELATED_NETWORK_DUE_TO_ALTERED_NOTCH3_IN_OVARIAN_CANCER",0.911389862,0.009231014,0.462332806,0.362204819,-0.184101791,-6.856352706,"NoSignifi"]
[1392,"PID_AR_NONGENOMIC_PATHWAY",0.910207953,0.009388786,0.462729766,0.362827516,-0.215154126,-6.857424167,"NoSignifi"]
[1391,"WP_KENNEDY_PATHWAY_FROM_SPHINGOLIPIDS",0.905250463,0.009857334,0.465470298,0.365446704,-0.138748013,-6.861903248,"NoSignifi"]
[1390,"REACTOME_APOPTOTIC_EXECUTION_PHASE",0.90345079,0.009507116,0.466085222,0.366400441,-0.199809948,-6.863523202,"NoSignifi"]
[1389,"REACTOME_ALPHA_LINOLENIC_OMEGA3_AND_LINOLEIC_OMEGA6_ACID_METABOLISM",0.899401498,0.009677684,0.468220365,0.368552035,-0.197134911,-6.867156347,"NoSignifi"]
[1388,"REACTOME_RNA_POLYMERASE_III_CHAIN_ELONGATION",0.89722754,0.012457153,0.469089831,0.369710409,-0.184782383,-6.869100158,"NoSignifi"]
[1387,"REACTOME_INTERLEUKIN_4_AND_INTERLEUKIN_13_SIGNALING",0.890846952,0.006050289,0.472612241,0.373123305,-0.064353268,-6.874778124,"NoSignifi"]
[1386,"REACTOME_INTERLEUKIN_15_SIGNALING",0.886994257,0.010983401,0.475031752,0.375193485,-0.190466071,-6.87818696,"NoSignifi"]
[1385,"WP_FOLLICLE_STIMULATING_HORMONE_FSH_SIGNALING_PATHWAY",0.885670827,0.008904928,0.47549543,0.375906244,-0.218172865,-6.879354514,"NoSignifi"]
[1384,"WP_HIPPOMERLIN_SIGNALING_DYSREGULATION",0.885422327,0.005255379,0.47549543,0.376040172,-0.112013925,-6.879573552,"NoSignifi"]
[1383,"REACTOME_MAPK6_MAPK4_SIGNALING",0.88236316,0.010889367,0.477176804,0.377691307,-0.17906068,-6.882264983,"NoSignifi"]
[1382,"REACTOME_PURINE_SALVAGE",0.880369287,0.011736061,0.478335918,0.37876987,-0.150608471,-6.884014167,"NoSignifi"]
[1381,"REACTOME_RMTS_METHYLATE_HISTONE_ARGININES",0.87942429,0.009435938,0.478778664,0.379281717,-0.242621608,-6.884841812,"NoSignifi"]
[1380,"REACTOME_TCR_SIGNALING",0.878303502,0.00939923,0.479059212,0.379889332,-0.130849558,-6.885822267,"NoSignifi"]
[1379,"REACTOME_SIGNALING_BY_NTRK3_TRKC",0.878286946,0.009559763,0.479059212,0.379898312,-0.241672222,-6.885836741,"NoSignifi"]
[1378,"REACTOME_TGF_BETA_RECEPTOR_SIGNALING_IN_EMT_EPITHELIAL_TO_MESENCHYMAL_TRANSITION",0.876661771,0.014404176,0.479854475,0.380780446,-0.089811747,-6.887256183,"NoSignifi"]
[1377,"REACTOME_NF_KB_IS_ACTIVATED_AND_SIGNALS_SURVIVAL",0.876026129,0.016888861,0.480085928,0.381125811,-0.178310514,-6.887810644,"NoSignifi"]
[1376,"REACTOME_CLEC7A_DECTIN_1_SIGNALING",0.866084087,0.010810145,0.485891123,0.386552655,-0.1797557,-6.896430637,"NoSignifi"]
[1375,"BIOCARTA_ERYTH_PATHWAY",0.86482455,0.010253359,0.486553542,0.387243523,-0.001847287,-6.897515669,"NoSignifi"]
[1374,"REACTOME_UCH_PROTEINASES",0.864024258,0.010926777,0.486899526,0.387682883,-0.18804883,-6.898204265,"NoSignifi"]
[1373,"WP_TCA_CYCLE_AKA_KREBS_OR_CITRIC_ACID_CYCLE",0.860405589,0.00995275,0.489131358,0.389673321,-0.301980678,-6.901309922,"NoSignifi"]
[1372,"BIOCARTA_CHREBP_PATHWAY",0.860194862,0.009463821,0.489131358,0.389789422,-0.145218658,-6.901490373,"NoSignifi"]
[1371,"REACTOME_INFECTIOUS_DISEASE",0.857491145,0.009043284,0.490588276,0.391280915,-0.142588651,-6.903801722,"NoSignifi"]
[1370,"REACTOME_ADENYLATE_CYCLASE_INHIBITORY_PATHWAY",0.851183061,0.012308173,0.494759224,0.3947742,-0.147355351,-6.909166096,"NoSignifi"]
[1369,"KEGG_NOD_LIKE_RECEPTOR_SIGNALING_PATHWAY",0.847508789,0.006064588,0.496779576,0.396817606,-0.113476204,-6.912272443,"NoSignifi"]
[1368,"WP_NANOPARTICLEMEDIATED_ACTIVATION_OF_RECEPTOR_SIGNALING",0.842974084,0.009728035,0.499437726,0.39934832,-0.21243579,-6.916087717,"NoSignifi"]
[1367,"BIOCARTA_RAC1_PATHWAY",0.842195261,0.009724212,0.499772006,0.399783939,-0.209780521,-6.916740921,"NoSignifi"]
[1366,"REACTOME_FORMATION_OF_TUBULIN_FOLDING_INTERMEDIATES_BY_CCT_TRIC",0.828169585,0.013072129,0.50942563,0.407677769,-0.210591149,-6.928401088,"NoSignifi"]
[1365,"REACTOME_REGULATION_OF_PTEN_MRNA_TRANSLATION",0.82673088,0.013799812,0.510229227,0.408492716,-0.206983137,-6.929586082,"NoSignifi"]
[1364,"REACTOME_SYNTHESIS_OF_ACTIVE_UBIQUITIN_ROLES_OF_E1_AND_E2_ENZYMES",0.825196823,0.011582918,0.511100917,0.409362742,-0.232029806,-6.930847345,"NoSignifi"]
[1363,"REACTOME_FGFR1_MUTANT_RECEPTOR_ACTIVATION",0.823413615,0.007821809,0.512149951,0.410375458,-0.192919347,-6.932310512,"NoSignifi"]
[1362,"BIOCARTA_VEGF_PATHWAY",0.821073581,0.007966496,0.513595411,0.411706661,-0.190904731,-6.934225769,"NoSignifi"]
[1361,"REACTOME_PROPIONYL_COA_CATABOLISM",0.820390391,0.015529847,0.513864943,0.4120958,-0.189838554,-6.934783916,"NoSignifi"]
[1360,"REACTOME_SCF_SKP2_MEDIATED_DEGRADATION_OF_P27_P21",0.819420792,0.012753013,0.513906561,0.412648448,-0.177308997,-6.935575253,"NoSignifi"]
[1359,"REACTOME_UNFOLDED_PROTEIN_RESPONSE_UPR",0.815154797,0.007171103,0.516507919,0.415085178,-0.215550894,-6.93904583,"NoSignifi"]
[1358,"REACTOME_GOLGI_TO_ER_RETROGRADE_TRANSPORT",0.813170614,0.006783608,0.517357945,0.416221435,-0.137987209,-6.940653884,"NoSignifi"]
[1357,"REACTOME_FCGR3A_MEDIATED_IL10_SYNTHESIS",0.81304915,0.006229951,0.517357945,0.416291051,-0.045403872,-6.940752195,"NoSignifi"]
[1356,"REACTOME_SARS_COV_INFECTIONS",0.808760903,0.007262698,0.519982608,0.418753255,-0.17683963,-6.944213649,"NoSignifi"]
[1355,"WP_EMBRYONIC_STEM_CELL_PLURIPOTENCY_PATHWAYS",0.808351813,0.005146206,0.520057329,0.418988592,-0.135227415,-6.944542909,"NoSignifi"]
[1354,"REACTOME_REGULATION_OF_GENE_EXPRESSION_IN_LATE_STAGE_BRANCHING_MORPHOGENESIS_PANCREATIC_BUD_PRECURSOR_CELLS",0.807706454,0.010166994,0.520300816,0.419360005,-0.162574857,-6.945061993,"NoSignifi"]
[1353,"REACTOME_GAMMA_CARBOXYLATION_TRANSPORT_AND_AMINO_TERMINAL_CLEAVAGE_OF_PROTEINS",0.806733729,0.012461666,0.520739749,0.419920187,-0.093305241,-6.945843607,"NoSignifi"]
[1352,"REACTOME_CREATINE_METABOLISM",0.806483146,0.008609556,0.520739749,0.420064566,0.139581449,-6.946044805,"NoSignifi"]
[1351,"REACTOME_GAP_FILLING_DNA_REPAIR_SYNTHESIS_AND_LIGATION_IN_GG_NER",0.805321155,0.010311639,0.520777092,0.420734457,-0.192604493,-6.946976976,"NoSignifi"]
[1350,"REACTOME_MASTL_FACILITATES_MITOTIC_PROGRESSION",0.80173441,0.012269435,0.523046477,0.422806179,-0.291899099,-6.94984586,"NoSignifi"]
[1349,"REACTOME_COPI_MEDIATED_ANTEROGRADE_TRANSPORT",0.798505056,0.007579993,0.524704434,0.424676576,-0.160483326,-6.952417933,"NoSignifi"]
[1348,"REACTOME_SIGNALING_BY_CYTOSOLIC_FGFR1_FUSION_MUTANTS",0.79527289,0.009718894,0.526804141,0.426553438,-0.257090336,-6.954981859,"NoSignifi"]
[1347,"REACTOME_THE_CITRIC_ACID_TCA_CYCLE_AND_RESPIRATORY_ELECTRON_TRANSPORT",0.786834951,0.008945651,0.530896022,0.431475951,-0.151327681,-6.9616263,"NoSignifi"]
[1346,"REACTOME_REGULATION_OF_RUNX2_EXPRESSION_AND_ACTIVITY",0.780485923,0.011092964,0.534769088,0.43520147,-0.155535318,-6.966579134,"NoSignifi"]
[1345,"WP_CELLULAR_PROTEOSTASIS",0.77803144,0.016077904,0.535704141,0.43664669,-0.283509452,-6.968483112,"NoSignifi"]
[1344,"REACTOME_INITIATION_OF_NUCLEAR_ENVELOPE_NE_REFORMATION",0.775089659,0.009108506,0.537611552,0.438382475,-0.216143632,-6.970757198,"NoSignifi"]
[1343,"REACTOME_REGULATION_OF_RUNX3_EXPRESSION_AND_ACTIVITY",0.77429846,0.012181626,0.537962689,0.438849995,-0.180942109,-6.971367349,"NoSignifi"]
[1342,"WP_PARKINUBIQUITIN_PROTEASOMAL_SYSTEM_PATHWAY",0.771643843,0.008676273,0.539665319,0.440420703,-0.210896656,-6.97340997,"NoSignifi"]
[1341,"PID_THROMBIN_PAR1_PATHWAY",0.767737695,0.007385519,0.541604316,0.442737784,-0.187437902,-6.976402844,"NoSignifi"]
[1340,"WP_TRANSCRIPTIONAL_ACTIVATION_BY_NRF2_IN_RESPONSE_TO_PHYTOCHEMICALS",0.767140606,0.010561363,0.541604316,0.443092585,-0.23190037,-6.976858995,"NoSignifi"]
[1339,"REACTOME_SMOOTH_MUSCLE_CONTRACTION",0.766986657,0.010454857,0.541604316,0.44318409,-0.147562575,-6.976976547,"NoSignifi"]
[1338,"REACTOME_NR1H2_AND_NR1H3_MEDIATED_SIGNALING",0.766905496,0.007107175,0.541604316,0.443232335,-0.239393629,-6.977038511,"NoSignifi"]
[1337,"REACTOME_UB_SPECIFIC_PROCESSING_PROTEASES",0.76651841,0.007157863,0.541604316,0.443462477,-0.188923299,-6.977333947,"NoSignifi"]
[1336,"REACTOME_MITOCHONDRIAL_FATTY_ACID_BETA_OXIDATION",0.763655085,0.007489984,0.543239114,0.445166981,-0.152099998,-6.9795147,"NoSignifi"]
[1335,"WP_ARYL_HYDROCARBON_RECEPTOR_PATHWAY_WP2586",0.760844455,0.006466493,0.544837405,0.446843746,-0.190206446,-6.981647388,"NoSignifi"]
[1334,"REACTOME_TNFR1_INDUCED_NFKAPPAB_SIGNALING_PATHWAY",0.759972105,0.008378523,0.545248931,0.447364903,-0.168815322,-6.982307723,"NoSignifi"]
[1333,"PID_S1P_S1P2_PATHWAY",0.756810495,0.009731746,0.547105349,0.449256598,-0.217249416,-6.984694596,"NoSignifi"]
[1332,"REACTOME_ESTABLISHMENT_OF_SISTER_CHROMATID_COHESION",0.756153364,0.012892195,0.547360348,0.44965035,-0.292941778,-6.985189451,"NoSignifi"]
[1331,"REACTOME_ACYL_CHAIN_REMODELLING_OF_PC",0.753570667,0.006089677,0.548571742,0.451199796,0.094451473,-6.987130202,"NoSignifi"]
[1330,"REACTOME_KILLING_MECHANISMS",0.746423998,0.01036915,0.553124144,0.455503042,-0.157441756,-6.992465932,"NoSignifi"]
[1329,"WP_HEDGEHOG_SIGNALING_PATHWAY_WP4249",0.745842378,0.006262035,0.553139806,0.45585427,-0.197451068,-6.992897936,"NoSignifi"]
[1328,"REACTOME_FLT3_SIGNALING",0.744171082,0.007423284,0.554097357,0.456864375,-0.21125147,-6.994137433,"NoSignifi"]
[1327,"WP_MAP3K1_ROLE_IN_PROMOTING_AND_BLOCKING_GONADAL_DETERMINATION",0.739244596,0.009964403,0.557221039,0.459849179,-0.164351575,-6.997774936,"NoSignifi"]
[1326,"WP_FGF23_SIGNALING_IN_HYPOPHOSPHATEMIC_RICKETS_AND_RELATED_DISORDERS",0.73751163,0.007286671,0.558082058,0.46090172,-0.06890627,-6.999048742,"NoSignifi"]
[1325,"REACTOME_THE_NLRP3_INFLAMMASOME",0.731370827,0.009775289,0.561958759,0.464642252,-0.164682371,-7.003538448,"NoSignifi"]
[1324,"WP_EGFR_TYROSINE_KINASE_INHIBITOR_RESISTANCE",0.730153005,0.00536147,0.562594147,0.465386065,-0.191912934,-7.004424373,"NoSignifi"]
[1323,"REACTOME_VIRAL_MESSENGER_RNA_SYNTHESIS",0.727087935,0.005946699,0.564630877,0.467261053,-0.221281764,-7.006647577,"NoSignifi"]
[1322,"REACTOME_PTK6_REGULATES_RHO_GTPASES_RAS_GTPASE_AND_MAP_KINASES",0.724099288,0.010271166,0.566614348,0.46909332,-0.235015843,-7.008806348,"NoSignifi"]
[1321,"WP_MIR222_IN_EXERCISEINDUCED_CARDIAC_GROWTH",0.720527411,0.013983794,0.568043573,0.471288359,-0.334499464,-7.011374744,"NoSignifi"]
[1320,"REACTOME_INNATE_IMMUNE_SYSTEM",0.719875976,0.004551162,0.56813206,0.471689298,-0.125267907,-7.011841796,"NoSignifi"]
[1319,"REACTOME_RESPONSE_OF_EIF2AK1_HRI_TO_HEME_DEFICIENCY",0.719511781,0.010543173,0.568171645,0.471913532,-0.173821176,-7.012102725,"NoSignifi"]
[1318,"REACTOME_STABILIZATION_OF_P53",0.718788409,0.01116523,0.568477551,0.472359083,-0.186089992,-7.012620597,"NoSignifi"]
[1317,"WP_OMEGA3_OMEGA6_FATTY_ACID_SYNTHESIS",0.717831429,0.007930812,0.56894699,0.472948879,-0.136567905,-7.013304911,"NoSignifi"]
[1316,"REACTOME_TRANSLATION_OF_REPLICASE_AND_ASSEMBLY_OF_THE_REPLICATION_TRANSCRIPTION_COMPLEX",0.716080041,0.0096207,0.569794764,0.474029325,-0.226347539,-7.014554929,"NoSignifi"]
[1315,"REACTOME_DOWNREGULATION_OF_ERBB4_SIGNALING",0.715480889,0.014913271,0.57000866,0.474399258,-0.170924232,-7.014981861,"NoSignifi"]
[1314,"REACTOME_AUF1_HNRNP_D0_BINDS_AND_DESTABILIZES_MRNA",0.713059358,0.011909806,0.571488895,0.475895996,-0.178784627,-7.01670371,"NoSignifi"]
[1313,"REACTOME_INTERLEUKIN_1_FAMILY_SIGNALING",0.712865096,0.006983506,0.571488895,0.47601618,-0.137162019,-7.016841588,"NoSignifi"]
[1312,"REACTOME_G_BETA_GAMMA_SIGNALLING_THROUGH_CDC42",0.704194773,0.008968567,0.577375245,0.481397194,-0.08907375,-7.022957169,"NoSignifi"]
[1311,"REACTOME_FORMATION_OF_THE_BETA_CATENIN_TCF_TRANSACTIVATING_COMPLEX",0.704025526,0.006626002,0.577375245,0.481502562,-0.224987533,-7.023075802,"NoSignifi"]
[1310,"BIOCARTA_ETS_PATHWAY",0.698943186,0.008761072,0.580941725,0.4846725,-0.279386527,-7.026624983,"NoSignifi"]
[1309,"REACTOME_CELL_CELL_JUNCTION_ORGANIZATION",0.696920976,0.004605947,0.582222249,0.485936926,-0.055709037,-7.028030018,"NoSignifi"]
[1308,"BIOCARTA_RAB_PATHWAY",0.696119895,0.010246806,0.582587875,0.48643831,-0.2004829,-7.028585485,"NoSignifi"]
[1307,"PID_NFAT_3PATHWAY",0.69391659,0.006503518,0.583065187,0.487818768,-0.188257481,-7.030109957,"NoSignifi"]
[1306,"REACTOME_ACYL_CHAIN_REMODELING_OF_DAG_AND_TAG",0.683523972,0.010201653,0.589694912,0.494358584,-0.121577033,-7.037235507,"NoSignifi"]
[1305,"REACTOME_DEPOLYMERISATION_OF_THE_NUCLEAR_LAMINA",0.682759539,0.008048111,0.590033863,0.494841468,-0.225806346,-7.037755385,"NoSignifi"]
[1304,"SIG_IL4RECEPTOR_IN_B_LYPHOCYTES",0.676712481,0.006651334,0.594121929,0.498670208,-0.288020309,-7.041847406,"NoSignifi"]
[1303,"REACTOME_MITOTIC_PROPHASE",0.675612204,0.004632074,0.59471529,0.499368547,-0.215151437,-7.042588046,"NoSignifi"]
[1302,"REACTOME_G_PROTEIN_MEDIATED_EVENTS",0.673241711,0.005361062,0.59627002,0.50087485,-0.175470004,-7.044179627,"NoSignifi"]
[1301,"REACTOME_UPTAKE_AND_FUNCTION_OF_DIPHTHERIA_TOXIN",0.672252262,0.017040298,0.596780062,0.501504296,-0.181753836,-7.044842302,"NoSignifi"]
[1300,"BIOCARTA_FBW7_PATHWAY",0.66550958,0.010086814,0.600981034,0.505804847,-0.285958684,-7.049332217,"NoSignifi"]
[1299,"REACTOME_MICRORNA_MIRNA_BIOGENESIS",0.665447928,0.007744713,0.600981034,0.505844259,-0.255092526,-7.049373062,"NoSignifi"]
[1298,"REACTOME_SYNTHESIS_OF_EPOXY_EET_AND_DIHYDROXYEICOSATRIENOIC_ACIDS_DHET",0.659202276,0.007106605,0.605250089,0.509845225,0.223848113,-7.053491264,"NoSignifi"]
[1297,"REACTOME_VESICLE_MEDIATED_TRANSPORT",0.654873579,0.004210051,0.608310224,0.512627882,-0.153786779,-7.056322708,"NoSignifi"]
[1296,"BIOCARTA_GATA3_PATHWAY",0.654227406,0.007587971,0.60855757,0.513043945,-0.15104616,-7.056743776,"NoSignifi"]
[1295,"BIOCARTA_P27_PATHWAY",0.65107538,0.010030457,0.610483318,0.515076023,-0.238867855,-7.058791789,"NoSignifi"]
[1294,"REACTOME_COOPERATION_OF_PREFOLDIN_AND_TRIC_CCT_IN_ACTIN_AND_TUBULIN_FOLDING",0.65063592,0.009986007,0.610575763,0.51535967,-0.200032655,-7.059076541,"NoSignifi"]
[1293,"REACTOME_C_TYPE_LECTIN_RECEPTORS_CLRS",0.648581724,0.006966658,0.611659714,0.516686616,-0.163284036,-7.060405024,"NoSignifi"]
[1292,"REACTOME_ASYMMETRIC_LOCALIZATION_OF_PCP_PROTEINS",0.648157483,0.009661231,0.611740478,0.516960882,-0.160937823,-7.060678865,"NoSignifi"]
[1291,"PID_HES_HEY_PATHWAY",0.646604953,0.005804681,0.612440753,0.517965217,-0.219207523,-7.061679471,"NoSignifi"]
[1290,"PID_HDAC_CLASSIII_PATHWAY",0.644906597,0.006425374,0.613029837,0.519065044,-0.211534226,-7.062771315,"NoSignifi"]
[1289,"REACTOME_SIGNALING_BY_ACTIVIN",0.64402529,0.007496143,0.61343936,0.519636238,-0.26713593,-7.063336762,"NoSignifi"]
[1288,"REACTOME_OLFACTORY_SIGNALING_PATHWAY",0.641403632,0.014664023,0.614958471,0.52133731,-0.111852265,-7.065014247,"NoSignifi"]
[1287,"WP_ETHANOL_EFFECTS_ON_HISTONE_MODIFICATIONS",0.639782325,0.005011297,0.615860416,0.522390733,-0.195929983,-7.066048227,"NoSignifi"]
[1286,"REACTOME_INTERLEUKIN_1_SIGNALING",0.639505792,0.007785066,0.615860416,0.522570516,-0.142265131,-7.066224324,"NoSignifi"]
[1285,"KEGG_VASCULAR_SMOOTH_MUSCLE_CONTRACTION",0.639269392,0.004387739,0.615860416,0.522724233,-0.105042369,-7.066374804,"NoSignifi"]
[1284,"KEGG_PROTEIN_EXPORT",0.637276016,0.00995786,0.617083366,0.524021327,-0.175528886,-7.067641467,"NoSignifi"]
[1283,"REACTOME_PERK_REGULATES_GENE_EXPRESSION",0.637035534,0.006912,0.617083366,0.524177921,-0.232817999,-7.067794011,"NoSignifi"]
[1282,"REACTOME_SIGNALING_BY_PDGFR_IN_DISEASE",0.633452123,0.007275251,0.619133088,0.526514158,-0.260838882,-7.07006024,"NoSignifi"]
[1281,"REACTOME_RHOBTB1_GTPASE_CYCLE",0.633405416,0.00872515,0.619133088,0.526544644,-0.220796224,-7.070089694,"NoSignifi"]
[1280,"WP_SYNAPTIC_SIGNALING_PATHWAYS_ASSOCIATED_WITH_AUTISM_SPECTRUM_DISORDER",0.629322074,0.004927198,0.620795924,0.529213366,-0.15096601,-7.072656323,"NoSignifi"]
[1279,"WP_SREBF_AND_MIR33_IN_CHOLESTEROL_AND_LIPID_HOMEOSTASIS",0.62555657,0.006389151,0.623366298,0.531680449,-0.280808718,-7.075008467,"NoSignifi"]
[1278,"PID_NECTIN_PATHWAY",0.625337035,0.00792256,0.623366298,0.531824464,-0.173431293,-7.075145165,"NoSignifi"]
[1277,"REACTOME_REGULATION_OF_LOCALIZATION_OF_FOXO_TRANSCRIPTION_FACTORS",0.624722964,0.010080022,0.623592402,0.532227399,-0.267690456,-7.075527276,"NoSignifi"]
[1276,"KEGG_NEUROTROPHIN_SIGNALING_PATHWAY",0.624248098,0.004297535,0.623711472,0.532539098,-0.148713327,-7.075822508,"NoSignifi"]
[1275,"WP_ARACHIDONATE_EPOXYGENASE_EPOXIDE_HYDROLASE",0.623589779,0.016522973,0.623971604,0.532971367,-0.156236068,-7.076231424,"NoSignifi"]
[1274,"REACTOME_AUTOPHAGY",0.619147372,0.005965352,0.62659686,0.535893,-0.164079469,-7.07897956,"NoSignifi"]
[1273,"REACTOME_REGULATION_OF_FOXO_TRANSCRIPTIONAL_ACTIVITY_BY_ACETYLATION",0.618969803,0.009338908,0.62659686,0.53600995,-0.224989975,-7.079088999,"NoSignifi"]
[1272,"PID_PDGFRA_PATHWAY",0.618896942,0.007469024,0.62659686,0.536057941,-0.19474804,-7.079133895,"NoSignifi"]
[1271,"WP_TYPE_II_INTERFERON_SIGNALING_IFNG",0.617667999,0.005785701,0.62729645,0.536867727,-0.143077722,-7.079890362,"NoSignifi"]
[1270,"WP_ATM_SIGNALING_IN_DEVELOPMENT_AND_DISEASE",0.614585912,0.004536349,0.629424855,0.538901307,-0.221354672,-7.081780908,"NoSignifi"]
[1269,"WP_RAC1PAK1P38MMP2_PATHWAY",0.609365339,0.004572843,0.632960302,0.542354667,-0.187726704,-7.084961629,"NoSignifi"]
[1268,"REACTOME_RELEASE_OF_APOPTOTIC_FACTORS_FROM_THE_MITOCHONDRIA",0.607880986,0.01425583,0.633859411,0.543338566,-0.241999755,-7.085861044,"NoSignifi"]
[1267,"REACTOME_ER_QUALITY_CONTROL_COMPARTMENT_ERQC",0.597487013,0.007533764,0.641421721,0.550252989,-0.273009608,-7.092097633,"NoSignifi"]
[1266,"REACTOME_ESTROGEN_STIMULATED_SIGNALING_THROUGH_PRKCZ",0.595334024,0.010548456,0.642592973,0.551690633,-0.27306672,-7.093376026,"NoSignifi"]
[1265,"REACTOME_TRANSPORT_OF_THE_SLBP_DEPENDANT_MATURE_MRNA",0.592272475,0.004503513,0.644680187,0.553738137,-0.255749484,-7.095185958,"NoSignifi"]
[1264,"REACTOME_REGULATION_OF_RAS_BY_GAPS",0.589470664,0.008331194,0.646403411,0.555615192,-0.17164207,-7.096834162,"NoSignifi"]
[1263,"WP_S1P_RECEPTOR_SIGNAL_TRANSDUCTION",0.588042319,0.005788267,0.647264442,0.556573297,-0.171872814,-7.0976714,"NoSignifi"]
[1262,"REACTOME_COHESIN_LOADING_ONTO_CHROMATIN",0.583688491,0.010654898,0.650157222,0.559498721,-0.28727426,-7.100210907,"NoSignifi"]
[1261,"KEGG_FC_EPSILON_RI_SIGNALING_PATHWAY",0.583292654,0.003395793,0.650212233,0.559765062,-0.105649878,-7.100440856,"NoSignifi"]
[1260,"WP_ANTIVIRAL_AND_ANTIINFLAMMATORY_EFFECTS_OF_NRF2_ON_SARSCOV2_PATHWAY",0.580878333,0.00519221,0.651845725,0.561390879,-0.112366747,-7.101840003,"NoSignifi"]
[1259,"REACTOME_CELLULAR_RESPONSE_TO_HYPOXIA",0.578076411,0.008437918,0.653528727,0.56328057,-0.170811507,-7.103456498,"NoSignifi"]
[1258,"WP_MATRIX_METALLOPROTEINASES",0.563782746,0.006363476,0.663138098,0.572968076,-0.073987234,-7.111581258,"NoSignifi"]
[1257,"REACTOME_MITOTIC_TELOPHASE_CYTOKINESIS",0.560623034,0.009172981,0.665185766,0.575120196,-0.249813965,-7.113349848,"NoSignifi"]
[1256,"REACTOME_REGULATION_OF_IFNG_SIGNALING",0.559008909,0.006511754,0.665920087,0.57622107,-0.22779342,-7.11424949,"NoSignifi"]
[1255,"WP_TRANSLATION_FACTORS",0.556968699,0.007836813,0.666363956,0.577613968,-0.145634278,-7.115382903,"NoSignifi"]
[1254,"REACTOME_REGULATION_OF_HSF1_MEDIATED_HEAT_SHOCK_RESPONSE",0.552832009,0.004297798,0.668996653,0.580443038,-0.19574579,-7.117668272,"NoSignifi"]
[1253,"REACTOME_DEFECTIVE_EXT2_CAUSES_EXOSTOSES_2",0.550839461,0.007063564,0.670309702,0.58180805,-0.262539427,-7.118763005,"NoSignifi"]
[1252,"REACTOME_DEVELOPMENTAL_BIOLOGY",0.54863136,0.004626405,0.671747281,0.58332248,-0.125118379,-7.119971548,"NoSignifi"]
[1251,"WP_WHITE_FAT_CELL_DIFFERENTIATION",0.548360564,0.005222962,0.671747281,0.583508332,-0.203906229,-7.120119427,"NoSignifi"]
[1250,"KEGG_EPITHELIAL_CELL_SIGNALING_IN_HELICOBACTER_PYLORI_INFECTION",0.546897809,0.004247742,0.672642746,0.584512726,-0.133745388,-7.12091696,"NoSignifi"]
[1249,"WP_AUTOSOMAL_RECESSIVE_OSTEOPETROSIS_PATHWAYS",0.546174133,0.007484562,0.672954083,0.585009932,-0.172049366,-7.12131074,"NoSignifi"]
[1248,"REACTOME_MRNA_SPLICING_MINOR_PATHWAY",0.544348519,0.006611739,0.674136753,0.586265105,-0.2094758,-7.12230181,"NoSignifi"]
[1247,"WP_LEPTIN_AND_ADIPONECTIN",0.54266142,0.007600801,0.674949013,0.587426154,-0.193466906,-7.123214736,"NoSignifi"]
[1246,"REACTOME_P75NTR_RECRUITS_SIGNALLING_COMPLEXES",0.5414553,0.010025333,0.675642005,0.588256848,-0.138988065,-7.123865657,"NoSignifi"]
[1245,"REACTOME_INTERLEUKIN_12_SIGNALING",0.536034956,0.007740683,0.679674489,0.591996709,-0.13000097,-7.126773043,"NoSignifi"]
[1244,"REACTOME_CROSS_PRESENTATION_OF_SOLUBLE_EXOGENOUS_ANTIGENS_ENDOSOMES",0.535361074,0.008533927,0.679728556,0.592462429,-0.18059654,-7.127132459,"NoSignifi"]
[1243,"BIOCARTA_PKC_PATHWAY",0.534271635,0.008734919,0.680284819,0.593215694,-0.248611765,-7.127712557,"NoSignifi"]
[1242,"PID_IL4_2PATHWAY",0.530408074,0.004004168,0.68247899,0.59589059,-0.137509092,-7.129760278,"NoSignifi"]
[1241,"WP_NANOPARTICLE_TRIGGERED_AUTOPHAGIC_CELL_DEATH",0.529214399,0.005391754,0.68247899,0.596718129,-0.214229602,-7.130389932,"NoSignifi"]
[1240,"REACTOME_MAPK3_ERK1_ACTIVATION",0.528874142,0.007755109,0.68247899,0.596954115,-0.201952235,-7.130569155,"NoSignifi"]
[1239,"SA_B_CELL_RECEPTOR_COMPLEXES",0.52687008,0.006011365,0.683526742,0.598344898,-0.222428829,-7.131622413,"NoSignifi"]
[1238,"BIOCARTA_MEF2D_PATHWAY",0.519729811,0.006717806,0.688671062,0.603312035,-0.190206444,-7.135342572,"NoSignifi"]
[1237,"BIOCARTA_WNT_PATHWAY",0.518347898,0.005030671,0.689505754,0.604275504,-0.228499712,-7.136056703,"NoSignifi"]
[1236,"REACTOME_RUNX3_REGULATES_P14_ARF",0.51237911,0.008260392,0.693463639,0.608444857,-0.225107327,-7.139119357,"NoSignifi"]
[1235,"REACTOME_APOBEC3G_MEDIATED_RESISTANCE_TO_HIV_1_INFECTION",0.511445076,0.010870551,0.69368644,0.609098463,-0.141616891,-7.139595413,"NoSignifi"]
[1234,"REACTOME_PROSTACYCLIN_SIGNALLING_THROUGH_PROSTACYCLIN_RECEPTOR",0.511286138,0.006701252,0.69368644,0.609209714,-0.091049454,-7.139676333,"NoSignifi"]
[1233,"REACTOME_MTORC1_MEDIATED_SIGNALLING",0.511098205,0.006843114,0.69368644,0.609341271,-0.183993597,-7.139771983,"NoSignifi"]
[1232,"WP_VITAMIN_D_IN_INFLAMMATORY_DISEASES",0.504669157,0.005272509,0.697189619,0.613849352,-0.201890993,-7.143022937,"NoSignifi"]
[1231,"REACTOME_INTERLEUKIN_36_PATHWAY",0.503212618,0.0041795,0.697576279,0.614872726,0.348742987,-7.143753743,"NoSignifi"]
[1230,"REACTOME_PCP_CE_PATHWAY",0.498534618,0.006594474,0.700507886,0.618164588,-0.152860585,-7.14608661,"NoSignifi"]
[1229,"SA_PTEN_PATHWAY",0.497449179,0.006054007,0.701107093,0.618929502,-0.29171675,-7.146624793,"NoSignifi"]
[1228,"REACTOME_BETA_CATENIN_INDEPENDENT_WNT_SIGNALING",0.495429721,0.00523394,0.702452403,0.620353722,-0.139455852,-7.147622961,"NoSignifi"]
[1227,"WP_FGFR3_SIGNALING_IN_CHONDROCYTE_PROLIFERATION_AND_TERMINAL_DIFFERENTIATION",0.49416734,0.004785225,0.703193149,0.621244739,-0.243182779,-7.148244863,"NoSignifi"]
[1226,"REACTOME_NEUROTRANSMITTER_RELEASE_CYCLE",0.493114004,0.003665816,0.703766865,0.621988633,-0.046573323,-7.148762566,"NoSignifi"]
[1225,"BIOCARTA_RARRXR_PATHWAY",0.492690271,0.007218951,0.703837354,0.622287994,-0.281979393,-7.148970514,"NoSignifi"]
[1224,"REACTOME_RUNX3_REGULATES_BCL2L11_BIM_TRANSCRIPTION",0.489745327,0.007677628,0.705923592,0.624370277,-0.238942658,-7.150410821,"NoSignifi"]
[1223,"REACTOME_METHIONINE_SALVAGE_PATHWAY",0.484371771,0.006991087,0.709957741,0.628177496,-0.287443114,-7.153016659,"NoSignifi"]
[1222,"WP_15Q133_COPY_NUMBER_VARIATION_SYNDROME",0.48281015,0.005730478,0.710845521,0.629285787,-0.052862872,-7.153768558,"NoSignifi"]
[1221,"PID_HDAC_CLASSI_PATHWAY",0.482590335,0.00394769,0.710845521,0.629441857,-0.19412154,-7.153874201,"NoSignifi"]
[1220,"REACTOME_ERYTHROPOIETIN_ACTIVATES_RAS",0.48110151,0.005838983,0.711769066,0.630499375,-0.277830403,-7.154588463,"NoSignifi"]
[1219,"WP_LIPID_METABOLISM_PATHWAY",0.476229029,0.003763646,0.715138251,0.633965603,-0.194001021,-7.156910604,"NoSignifi"]
[1218,"WP_GASTRIC_ACID_PRODUCTION",0.474780169,0.00257586,0.715632302,0.634997863,0.303637303,-7.157596547,"NoSignifi"]
[1217,"BIOCARTA_CARM1_PATHWAY",0.474599433,0.006529943,0.715632302,0.635126681,-0.263160077,-7.157681967,"NoSignifi"]
[1216,"KEGG_ACUTE_MYELOID_LEUKEMIA",0.473466417,0.003399477,0.715999038,0.635934477,-0.216276937,-7.158216719,"NoSignifi"]
[1215,"REACTOME_CIRCADIAN_CLOCK",0.46311948,0.003945734,0.722708832,0.643331406,-0.240136117,-7.163041061,"NoSignifi"]
[1214,"KEGG_PANTOTHENATE_AND_COA_BIOSYNTHESIS",0.463087286,0.004325202,0.722708832,0.643354477,-0.059797405,-7.163055906,"NoSignifi"]
[1213,"REACTOME_SIGNALING_BY_MEMBRANE_TETHERED_FUSIONS_OF_PDGFRA_OR_PDGFRB",0.458651631,0.009341627,0.72597612,0.646536454,-0.090259213,-7.165091288,"NoSignifi"]
[1212,"KEGG_METABOLISM_OF_XENOBIOTICS_BY_CYTOCHROME_P450",0.450767048,0.003820457,0.731824318,0.652208537,0.028235826,-7.168660926,"NoSignifi"]
[1211,"REACTOME_REGULATION_OF_INNATE_IMMUNE_RESPONSES_TO_CYTOSOLIC_DNA",0.446766033,0.008323065,0.734507468,0.655094569,-0.170169802,-7.170448662,"NoSignifi"]
[1210,"BIOCARTA_HIF_PATHWAY",0.445540027,0.00727294,0.735089915,0.655979954,-0.222895099,-7.170993277,"NoSignifi"]
[1209,"WP_DNA_DAMAGE_RESPONSE_ONLY_ATM_DEPENDENT",0.445361085,0.002903582,0.735089915,0.65610922,-0.188795223,-7.171072641,"NoSignifi"]
[1208,"WP_MAMMARY_GLAND_DEVELOPMENT_PATHWAY_INVOLUTION_STAGE_4_OF_4",0.445000918,0.005963996,0.735104055,0.656369435,-0.146519499,-7.171232286,"NoSignifi"]
[1207,"REACTOME_ZBP1_DAI_MEDIATED_INDUCTION_OF_TYPE_I_IFNS",0.440390216,0.004153122,0.738003753,0.659704264,-0.213382158,-7.173264578,"NoSignifi"]
[1206,"REACTOME_RHOA_GTPASE_CYCLE",0.438210032,0.002474286,0.739491808,0.661283513,-0.15897205,-7.174218185,"NoSignifi"]
[1205,"REACTOME_RND1_GTPASE_CYCLE",0.431133112,0.003960562,0.744114877,0.666420161,-0.194191386,-7.177281003,"NoSignifi"]
[1204,"WP_MICRORNA_FOR_TARGETING_CANCER_GROWTH_AND_VASCULARIZATION_IN_GLIOBLASTOMA",0.429225935,0.008180582,0.745383236,0.667807143,-0.160576762,-7.178097881,"NoSignifi"]
[1203,"WP_PATHOGENIC_ESCHERICHIA_COLI_INFECTION",0.41931391,0.005609321,0.751318463,0.675033811,-0.155262429,-7.182285067,"NoSignifi"]
[1202,"KEGG_PATHOGENIC_ESCHERICHIA_COLI_INFECTION",0.41931389,0.005609321,0.751318463,0.675033826,-0.155262429,-7.182285075,"NoSignifi"]
[1201,"KEGG_VEGF_SIGNALING_PATHWAY",0.411749317,0.002946531,0.756216412,0.680569301,-0.129710844,-7.185414812,"NoSignifi"]
[1200,"KEGG_RETINOL_METABOLISM",0.41082441,0.002706444,0.756686586,0.681247304,0.221621298,-7.185793571,"NoSignifi"]
[1199,"WP_HEREDITARY_LEIOMYOMATOSIS_AND_RENAL_CELL_CARCINOMA_PATHWAY",0.405713763,0.005392969,0.759716082,0.6849983,-0.240154283,-7.187871081,"NoSignifi"]
[1198,"PID_P75_NTR_PATHWAY",0.401139098,0.003080698,0.762592653,0.688362516,-0.127903703,-7.189708656,"NoSignifi"]
[1197,"PID_TRKR_PATHWAY",0.394437524,0.003172664,0.7674543,0.693302011,-0.182220428,-7.192362965,"NoSignifi"]
[1196,"REACTOME_TNFR2_NON_CANONICAL_NF_KB_PATHWAY",0.385076661,0.004688698,0.772561633,0.700223427,-0.118181042,-7.195995702,"NoSignifi"]
[1195,"REACTOME_EPH_EPHRIN_MEDIATED_REPULSION_OF_CELLS",0.383017207,0.00379352,0.773732744,0.70174956,-0.137125068,-7.196783222,"NoSignifi"]
[1194,"REACTOME_G2_M_CHECKPOINTS",0.381863038,0.003955914,0.774326408,0.702605369,-0.120876728,-7.197222722,"NoSignifi"]
[1193,"REACTOME_PLATELET_AGGREGATION_PLUG_FORMATION",0.378108809,0.004644987,0.77710872,0.705391715,-0.174552875,-7.198643133,"NoSignifi"]
[1192,"WP_SYNAPTIC_VESICLE_PATHWAY",0.373413694,0.002891348,0.780664127,0.708881943,-0.080482738,-7.20039978,"NoSignifi"]
[1191,"REACTOME_CDT1_ASSOCIATION_WITH_THE_CDC6_ORC_ORIGIN_COMPLEX",0.368303078,0.005864227,0.783464216,0.712688007,-0.152205777,-7.20228694,"NoSignifi"]
[1190,"BIOCARTA_PPARA_PATHWAY",0.36181576,0.003254878,0.788141176,0.717529673,-0.22356377,-7.204645012,"NoSignifi"]
[1189,"KEGG_LIMONENE_AND_PINENE_DEGRADATION",0.358637431,0.005744959,0.789874597,0.719905914,-0.244238872,-7.20578501,"NoSignifi"]
[1188,"REACTOME_INTERCONVERSION_OF_NUCLEOTIDE_DI_AND_TRIPHOSPHATES",0.354318829,0.003854211,0.79312882,0.723139008,-0.166244563,-7.207317881,"NoSignifi"]
[1187,"PID_INTEGRIN5_PATHWAY",0.345125855,0.004480954,0.798335884,0.730037698,-0.142081382,-7.210519062,"NoSignifi"]
[1186,"REACTOME_G1_S_DNA_DAMAGE_CHECKPOINTS",0.343094262,0.004786368,0.799711786,0.731565245,-0.167994621,-7.211215153,"NoSignifi"]
[1185,"WP_FOCAL_ADHESION",0.341589122,0.002919505,0.800065942,0.732697641,-0.14239797,-7.211728213,"NoSignifi"]
[1184,"REACTOME_TRANSPORT_OF_MATURE_MRNAS_DERIVED_FROM_INTRONLESS_TRANSCRIPTS",0.339779253,0.002475854,0.801188393,0.734060072,-0.263851162,-7.212342161,"NoSignifi"]
[1183,"WP_SPINAL_CORD_INJURY",0.33950675,0.002445567,0.801188393,0.73426528,-0.06973361,-7.212434318,"NoSignifi"]
[1182,"REACTOME_ANTIGEN_PROCESSING_CROSS_PRESENTATION",0.338565528,0.004370204,0.801651371,0.734974209,-0.16216887,-7.212752057,"NoSignifi"]
[1181,"REACTOME_DNA_DOUBLE_STRAND_BREAK_REPAIR",0.338226527,0.0017318,0.801651371,0.7352296,-0.120146429,-7.212866281,"NoSignifi"]
[1180,"WNT_SIGNALING",0.337230904,0.002317435,0.802174792,0.735979836,-0.151473133,-7.213201089,"NoSignifi"]
[1179,"WP_CIRCADIAN_RHYTHM_GENES",0.33443772,0.002311189,0.8033083,0.738085941,-0.154764075,-7.214135112,"NoSignifi"]
[1178,"WP_MEVALONATE_ARM_OF_CHOLESTEROL_BIOSYNTHESIS_PATHWAY",0.33441634,0.003734544,0.8033083,0.738102069,-0.279489292,-7.214142231,"NoSignifi"]
[1177,"KEGG_HUNTINGTONS_DISEASE",0.333282623,0.003728082,0.803581366,0.738957477,-0.160060975,-7.214519099,"NoSignifi"]
[1176,"BIOCARTA_HCMV_PATHWAY",0.333007726,0.003789023,0.803581366,0.739164941,-0.340103428,-7.214610287,"NoSignifi"]
[1175,"REACTOME_SIGNALING_BY_MRAS_COMPLEX_MUTANTS",0.331915137,0.005355916,0.804183535,0.7399897,-0.212332307,-7.214971973,"NoSignifi"]
[1174,"BIOCARTA_EEA1_PATHWAY",0.325649454,0.005348796,0.808549338,0.744725205,-0.153841014,-7.217023186,"NoSignifi"]
[1173,"PID_DNA_PK_PATHWAY",0.325158958,0.003913309,0.808549338,0.745096325,-0.089814373,-7.217182112,"NoSignifi"]
[1172,"WP_HEAD_AND_NECK_SQUAMOUS_CELL_CARCINOMA",0.323377693,0.002685452,0.809716447,0.746444566,-0.245143101,-7.217757244,"NoSignifi"]
[1171,"REACTOME_CLEC7A_DECTIN_1_INDUCES_NFAT_ACTIVATION",0.322947614,0.004988777,0.809773832,0.74677021,-0.257398042,-7.217895634,"NoSignifi"]
[1170,"REACTOME_SIGNALING_BY_RHO_GTPASES_MIRO_GTPASES_AND_RHOBTB3",0.316864913,0.001966486,0.813881518,0.75138068,-0.158614586,-7.219833191,"NoSignifi"]
[1169,"REACTOME_RHO_GTPASE_CYCLE",0.315410195,0.001898696,0.813889568,0.752484629,-0.171538066,-7.220291112,"NoSignifi"]
[1168,"KEGG_TERPENOID_BACKBONE_BIOSYNTHESIS",0.312807196,0.003377173,0.815433357,0.754461243,-0.241684575,-7.221105236,"NoSignifi"]
[1167,"REACTOME_REGULATION_OF_MRNA_STABILITY_BY_PROTEINS_THAT_BIND_AU_RICH_ELEMENTS",0.311324305,0.004103992,0.816354006,0.755588013,-0.180137916,-7.221566014,"NoSignifi"]
[1166,"REACTOME_NOTCH2_INTRACELLULAR_DOMAIN_REGULATES_TRANSCRIPTION",0.309931513,0.004908607,0.817200559,0.756646796,-0.209578792,-7.221996802,"NoSignifi"]
[1165,"PID_TRAIL_PATHWAY",0.30900068,0.002679222,0.817667628,0.757354658,-0.152905903,-7.22228363,"NoSignifi"]
[1164,"WP_TRANSCRIPTION_FACTOR_REGULATION_IN_ADIPOGENESIS",0.303180012,0.003085321,0.821056581,0.761785646,-0.202831341,-7.224057655,"NoSignifi"]
[1163,"KEGG_ALDOSTERONE_REGULATED_SODIUM_REABSORPTION",0.303060969,0.002422046,0.821056581,0.761876349,-0.143463261,-7.224093585,"NoSignifi"]
[1162,"WP_CCL18_SIGNALING_PATHWAY",0.301947585,0.003534055,0.821374702,0.762724841,-0.123291647,-7.224428947,"NoSignifi"]
[1161,"PID_TCR_JNK_PATHWAY",0.300315776,0.003441962,0.82211807,0.763968931,-0.157077982,-7.224918235,"NoSignifi"]
[1160,"WP_CARDIAC_HYPERTROPHIC_RESPONSE",0.298418772,0.002432692,0.82337682,0.765415972,-0.209240992,-7.225483706,"NoSignifi"]
[1159,"REACTOME_MAPK1_ERK2_ACTIVATION",0.295825473,0.004938128,0.824637018,0.767395475,-0.17843259,-7.226250937,"NoSignifi"]
[1158,"SIG_CHEMOTAXIS",0.29579243,0.003214679,0.824637018,0.767420707,-0.173509547,-7.22626067,"NoSignifi"]
[1157,"PID_P53_DOWNSTREAM_PATHWAY",0.294965522,0.001867406,0.825017024,0.768052224,-0.169139145,-7.226503877,"NoSignifi"]
[1156,"REACTOME_SIGNALING_BY_FLT3_FUSION_PROTEINS",0.292861958,0.003599887,0.826145642,0.769659429,-0.264014541,-7.227119499,"NoSignifi"]
[1155,"REACTOME_EPHB_MEDIATED_FORWARD_SIGNALING",0.291285513,0.004010584,0.827140163,0.770864544,-0.175687641,-7.227577969,"NoSignifi"]
[1154,"WP_PHOTODYNAMIC_THERAPYINDUCED_NFKB_SURVIVAL_SIGNALING",0.290861764,0.002372858,0.827188901,0.771188575,-0.127584463,-7.227700784,"NoSignifi"]
[1153,"REACTOME_TRANSLATION_OF_SARS_COV_2_STRUCTURAL_PROTEINS",0.279669313,0.002891468,0.835399956,0.779761458,-0.197377247,-7.23087996,"NoSignifi"]
[1152,"REACTOME_SUPPRESSION_OF_PHAGOSOMAL_MATURATION",0.277059644,0.004681855,0.837020568,0.781764242,-0.146799363,-7.231603297,"NoSignifi"]
[1151,"WP_OVERLAP_BETWEEN_SIGNAL_TRANSDUCTION_PATHWAYS_CONTRIBUTING_TO_LMNA_LAMINOPATHIES",0.276426968,0.002415323,0.837238741,0.782250006,-0.198469706,-7.231777638,"NoSignifi"]
[1150,"WP_IL3_SIGNALING_PATHWAY",0.273177607,0.002292707,0.839305262,0.784746179,-0.153443304,-7.232666757,"NoSignifi"]
[1149,"REACTOME_DEX_H_BOX_HELICASES_ACTIVATE_TYPE_I_IFN_AND_INFLAMMATORY_CYTOKINES_PRODUCTION",0.268300995,0.004170926,0.842406013,0.788496568,-0.27360512,-7.233981411,"NoSignifi"]
[1148,"REACTOME_CALNEXIN_CALRETICULIN_CYCLE",0.264959368,0.00335967,0.844560643,0.791069308,-0.244153377,-7.234868587,"NoSignifi"]
[1147,"REACTOME_FOXO_MEDIATED_TRANSCRIPTION_OF_CELL_CYCLE_GENES",0.264942588,0.003561726,0.844560643,0.791082232,-0.304466713,-7.234873014,"NoSignifi"]
[1146,"REACTOME_COPI_INDEPENDENT_GOLGI_TO_ER_RETROGRADE_TRAFFIC",0.25805779,0.002957821,0.8493111,0.796390065,-0.176895913,-7.236665708,"NoSignifi"]
[1145,"REACTOME_ORC1_REMOVAL_FROM_CHROMATIN",0.256943118,0.003762892,0.849618157,0.797250315,-0.133574376,-7.236951513,"NoSignifi"]
[1144,"REACTOME_OAS_ANTIVIRAL_RESPONSE",0.256270214,0.004129981,0.849866662,0.797769749,-0.20720525,-7.237123448,"NoSignifi"]
[1143,"REACTOME_TRANSCRIPTIONAL_REGULATION_BY_SMALL_RNAS",0.254439529,0.002068909,0.850768528,0.799183362,-0.216060177,-7.237588928,"NoSignifi"]
[1142,"WP_UNFOLDED_PROTEIN_RESPONSE",0.253689725,0.002756329,0.850768528,0.799762534,-0.187367997,-7.237778615,"NoSignifi"]
[1141,"REACTOME_NEGATIVE_REGULATION_OF_FGFR3_SIGNALING",0.251344599,0.002815284,0.852379646,0.801574691,-0.203907599,-7.238368274,"NoSignifi"]
[1140,"WP_ENERGY_METABOLISM",0.250986829,0.001857743,0.852379646,0.801851247,-0.206539794,-7.238457751,"NoSignifi"]
[1139,"REACTOME_RHO_GTPASES_ACTIVATE_IQGAPS",0.242473031,0.003913718,0.857757859,0.808439643,-0.156918895,-7.240549405,"NoSignifi"]
[1138,"WP_CYTOKINES_AND_INFLAMMATORY_RESPONSE",0.242294354,0.002007782,0.857757859,0.808578059,0.123329938,-7.240592529,"NoSignifi"]
[1137,"REACTOME_CYCLIN_D_ASSOCIATED_EVENTS_IN_G1",0.242209145,0.002363135,0.857757859,0.808644071,-0.190090465,-7.240613083,"NoSignifi"]
[1136,"PID_ATF2_PATHWAY",0.241103863,0.002026521,0.858359591,0.809500456,-0.182871671,-7.240879044,"NoSignifi"]
[1135,"REACTOME_TRANSFERRIN_ENDOCYTOSIS_AND_RECYCLING",0.234299173,0.002417091,0.863647015,0.8147778,-0.132611014,-7.242489638,"NoSignifi"]
[1134,"REACTOME_RECEPTOR_MEDIATED_MITOPHAGY",0.23201835,0.003471158,0.865215106,0.816548578,-0.217490776,-7.243019167,"NoSignifi"]
[1133,"REACTOME_CYCLIN_A_CDK2_ASSOCIATED_EVENTS_AT_S_PHASE_ENTRY",0.227966783,0.002838962,0.867621636,0.819696426,-0.176424185,-7.243947029,"NoSignifi"]
[1132,"REACTOME_ATF6_ATF6_ALPHA_ACTIVATES_CHAPERONES",0.227267044,0.00385344,0.867869799,0.820240382,-0.210882934,-7.244105623,"NoSignifi"]
[1131,"REACTOME_PLASMA_LIPOPROTEIN_ASSEMBLY",0.226913174,0.002854999,0.867869799,0.820515502,-0.185471159,-7.244185641,"NoSignifi"]
[1130,"REACTOME_RESOLUTION_OF_SISTER_CHROMATID_COHESION",0.224977911,0.001598347,0.869152002,0.822020486,-0.115354399,-7.244621044,"NoSignifi"]
[1129,"REACTOME_ESR_MEDIATED_SIGNALING",0.223962066,0.001652324,0.869649202,0.822810735,-0.191332059,-7.2448481,"NoSignifi"]
[1128,"WP_ANGIOPOIETINLIKE_PROTEIN_8_REGULATORY_PATHWAY",0.22357782,0.001203139,0.869649202,0.823109696,-0.217026112,-7.244933716,"NoSignifi"]
[1127,"REACTOME_INTRINSIC_PATHWAY_FOR_APOPTOSIS",0.223233577,0.002107342,0.869649202,0.823377554,-0.159100545,-7.245010295,"NoSignifi"]
[1126,"REACTOME_FATTY_ACIDS",0.222867578,0.001468253,0.869649202,0.823662363,0.407253447,-7.245091584,"NoSignifi"]
[1125,"REACTOME_NONHOMOLOGOUS_END_JOINING_NHEJ",0.220689398,0.001775914,0.870819978,0.825357837,-0.189710781,-7.245572601,"NoSignifi"]
[1124,"REACTOME_TYPE_I_HEMIDESMOSOME_ASSEMBLY",0.220183881,0.004139237,0.870925767,0.825751443,-0.200626445,-7.245683561,"NoSignifi"]
[1123,"PID_INSULIN_GLUCOSE_PATHWAY",0.218591592,0.002804134,0.871923942,0.826991519,-0.216654926,-7.246031403,"NoSignifi"]
[1122,"WP_CONGENITAL_GENERALIZED_LIPODYSTROPHY_CGL",0.216853401,0.0026149,0.873041687,0.828345717,-0.245730957,-7.246408236,"NoSignifi"]
[1121,"WP_VITAMIN_D_RECEPTOR_PATHWAY",0.214446892,0.000835841,0.874708103,0.830221433,-0.035480115,-7.246924992,"NoSignifi"]
[1120,"REACTOME_INTERACTIONS_OF_VPR_WITH_HOST_CELLULAR_PROTEINS",0.213664367,0.001780952,0.874730117,0.830831569,-0.231105259,-7.247091783,"NoSignifi"]
[1119,"WP_LNCRNAMEDIATED_MECHANISMS_OF_THERAPEUTIC_RESISTANCE",0.203574101,0.002667719,0.881147915,0.838707985,-0.160857675,-7.249187853,"NoSignifi"]
[1118,"PID_PLK1_PATHWAY",0.197858882,0.001656924,0.884903153,0.843176497,-0.095056593,-7.250330114,"NoSignifi"]
[1117,"REACTOME_SIGNALING_BY_NUCLEAR_RECEPTORS",0.195911978,0.001225058,0.885562821,0.844699869,-0.183095323,-7.250711801,"NoSignifi"]
[1116,"WP_HFE_EFFECT_ON_HEPCIDIN_PRODUCTION",0.194350255,0.003139584,0.88653132,0.845922273,0.114560195,-7.251015247,"NoSignifi"]
[1115,"PID_HDAC_CLASSII_PATHWAY",0.19139664,0.002034486,0.888641567,0.848235163,-0.144807626,-7.2515825,"NoSignifi"]
[1114,"KEGG_ARACHIDONIC_ACID_METABOLISM",0.18969574,0.001253274,0.889409892,0.849567684,0.113218102,-7.251905222,"NoSignifi"]
[1113,"WP_PILOCYTIC_ASTROCYTOMA",0.18643101,0.003042345,0.891313605,0.852126543,-0.35501954,-7.252516589,"NoSignifi"]
[1112,"REACTOME_REGULATION_OF_RUNX1_EXPRESSION_AND_ACTIVITY",0.174468438,0.002106016,0.899697641,0.861515794,-0.243248431,-7.254666063,"NoSignifi"]
[1111,"REACTOME_MITOTIC_G1_PHASE_AND_G1_S_TRANSITION",0.172476557,0.001584607,0.90069873,0.863081134,-0.146489323,-7.255010132,"NoSignifi"]
[1110,"REACTOME_SELECTIVE_AUTOPHAGY",0.17198943,0.002003014,0.900743875,0.86346403,-0.160249477,-7.255093675,"NoSignifi"]
[1109,"REACTOME_DECTIN_1_MEDIATED_NONCANONICAL_NF_KB_SIGNALING",0.171649607,0.002642169,0.900743875,0.863731159,-0.175096616,-7.255151815,"NoSignifi"]
[1108,"REACTOME_CONDENSATION_OF_PROPHASE_CHROMOSOMES",0.170087606,0.002043041,0.9015207,0.864959225,-0.200141608,-7.255417579,"NoSignifi"]
[1107,"WP_MRNA_PROTEIN_AND_METABOLITE_INDUCATION_PATHWAY_BY_CYCLOSPORIN_A",0.168153665,0.003198296,0.901710345,0.866480166,-0.236778623,-7.25574326,"NoSignifi"]
[1106,"REACTOME_OPIOID_SIGNALLING",0.16395124,0.001201404,0.904834321,0.869786848,-0.154921402,-7.25643812,"NoSignifi"]
[1105,"REACTOME_NEGATIVE_REGULATION_OF_FGFR4_SIGNALING",0.157361208,0.001767998,0.908323808,0.87497679,-0.208942487,-7.257492357,"NoSignifi"]
[1104,"REACTOME_MITOCHONDRIAL_TRANSLATION",0.156008434,0.001477108,0.909112608,0.876042833,-0.238163681,-7.257703416,"NoSignifi"]
[1103,"REACTOME_SUMOYLATION_OF_DNA_DAMAGE_RESPONSE_AND_REPAIR_PROTEINS",0.155205664,0.001059185,0.909451337,0.876675557,-0.212294625,-7.257827803,"NoSignifi"]
[1102,"REACTOME_DOWNSTREAM_SIGNAL_TRANSDUCTION",0.145534093,0.001383827,0.915765662,0.884304531,-0.246068512,-7.259275946,"NoSignifi"]
[1101,"PID_TGFBR_PATHWAY",0.137696552,0.001342946,0.921533241,0.890494735,-0.241277104,-7.260381154,"NoSignifi"]
[1100,"WP_G_PROTEIN_SIGNALING_PATHWAYS",0.132256628,0.000990512,0.924694399,0.89479522,-0.111373693,-7.261112303,"NoSignifi"]
[1099,"REACTOME_TRANSCRIPTION_OF_THE_HIV_GENOME",0.130879618,0.001080077,0.925497733,0.8958843,-0.228233668,-7.261292706,"NoSignifi"]
[1098,"WP_PI3KAKTMTOR_SIGNALING_PATHWAY_AND_THERAPEUTIC_OPPORTUNITIES",0.125697169,0.0012754,0.928119146,0.899984851,-0.19324894,-7.261954735,"NoSignifi"]
[1097,"WP_TCA_CYCLE_AND_DEFICIENCY_OF_PYRUVATE_DEHYDROGENASE_COMPLEX_PDHC",0.122942067,0.001379448,0.92907753,0.902165888,-0.331071876,-7.262295797,"NoSignifi"]
[1096,"REACTOME_RHOJ_GTPASE_CYCLE",0.119818721,0.000987916,0.930822593,0.904639333,-0.230819377,-7.262673303,"NoSignifi"]
[1095,"REACTOME_HSF1_ACTIVATION",0.118951731,0.001646909,0.931040232,0.905326086,-0.163203277,-7.26277637,"NoSignifi"]
[1094,"REACTOME_SEMA3A_PAK_DEPENDENT_AXON_REPULSION",0.116750637,0.00175035,0.93218781,0.907069917,-0.165270723,-7.263034672,"NoSignifi"]
[1093,"REACTOME_CRISTAE_FORMATION",0.112280552,0.001764871,0.934857963,0.910612741,-0.171685171,-7.263544397,"NoSignifi"]
[1092,"BIOCARTA_PARKIN_PATHWAY",0.105378565,0.00184078,0.939421151,0.916086472,-0.175929628,-7.264292355,"NoSignifi"]
[1091,"REACTOME_CELLULAR_RESPONSE_TO_HEAT_STRESS",0.10448434,0.000872844,0.939581349,0.916795948,-0.182668307,-7.26438579,"NoSignifi"]
[1090,"REACTOME_BETA_CATENIN_PHOSPHORYLATION_CASCADE",0.102271611,0.001382564,0.940731395,0.918551806,-0.242761498,-7.264613568,"NoSignifi"]
[1089,"BIOCARTA_FEEDER_PATHWAY",0.10064507,0.001395808,0.941079657,0.919842764,-0.107562747,-7.264777895,"NoSignifi"]
[1088,"WP_ACUTE_VIRAL_MYOCARDITIS",0.100242051,0.000699797,0.941082658,0.920162666,-0.161236889,-7.264818204,"NoSignifi"]
[1087,"REACTOME_PROCESSING_OF_CAPPED_INTRON_CONTAINING_PRE_MRNA",0.09900109,0.000844562,0.941765754,0.921147777,-0.202849818,-7.264941307,"NoSignifi"]
[1086,"WP_MOLYBDENUM_COFACTOR_MOCO_BIOSYNTHESIS",0.091151664,0.001359274,0.946834953,0.927381624,-0.049026479,-7.265684441,"NoSignifi"]
[1085,"REACTOME_MEMBRANE_TRAFFICKING",0.089148674,0.000568575,0.948133756,0.928973087,-0.161798789,-7.265864246,"NoSignifi"]
[1084,"REACTOME_CLASS_I_MHC_MEDIATED_ANTIGEN_PROCESSING_PRESENTATION",0.088337409,0.000634602,0.948139852,0.929617753,-0.178177737,-7.265935936,"NoSignifi"]
[1083,"PID_P38_MKK3_6PATHWAY",0.08644474,0.00087918,0.949347874,0.931121929,-0.216648842,-7.266100638,"NoSignifi"]
[1082,"REACTOME_KSRP_KHSRP_BINDS_AND_DESTABILIZES_MRNA",0.083233597,0.000900602,0.951297052,0.933674507,-0.283347905,-7.266371915,"NoSignifi"]
[1081,"BIOCARTA_IL4_PATHWAY",0.078369253,0.001105676,0.954582909,0.937542527,-0.259433001,-7.266763296,"NoSignifi"]
[1080,"REACTOME_REGULATION_OF_PTEN_GENE_TRANSCRIPTION",0.076296581,0.000677555,0.955606048,0.939191124,-0.255747254,-7.266922904,"NoSignifi"]
[1079,"BIOCARTA_AGPCR_PATHWAY",0.075078602,0.001081968,0.956264168,0.940160022,-0.120775361,-7.267014699,"NoSignifi"]
[1078,"WP_AFLATOXIN_B1_METABOLISM",0.071977622,0.002012679,0.958327776,0.942627241,-0.184095615,-7.267241743,"NoSignifi"]
[1077,"REACTOME_INTERLEUKIN_9_SIGNALING",0.068450521,0.001183596,0.959656076,0.94543416,-0.142596335,-7.267488347,"NoSignifi"]
[1076,"REACTOME_SNRNP_ASSEMBLY",0.065603148,0.000546262,0.961299348,0.947700637,-0.167307612,-7.267678389,"NoSignifi"]
[1075,"KEGG_CITRATE_CYCLE_TCA_CYCLE",0.061610246,0.000607141,0.963865377,0.950879653,-0.297970551,-7.26793129,"NoSignifi"]
[1074,"KEGG_GNRH_SIGNALING_PATHWAY",0.059505885,0.000405893,0.964315656,0.952555394,-0.154237666,-7.268058186,"NoSignifi"]
[1073,"REACTOME_REGULATION_OF_SIGNALING_BY_CBL",0.059354598,0.000748016,0.964315656,0.952675874,-0.146269501,-7.268067139,"NoSignifi"]
[1072,"REACTOME_HYALURONAN_METABOLISM",0.05858017,0.000619617,0.964335877,0.953292624,-0.156589185,-7.268112612,"NoSignifi"]
[1071,"PID_IL8_CXCR1_PATHWAY",0.052154802,0.000489763,0.968523363,0.958410792,-0.114663907,-7.2684668630000004,"NoSignifi"]
[1070,"REACTOME_P75NTR_SIGNALS_VIA_NF_KB",0.050686783,0.000858658,0.969375368,0.9595804,-0.1623312,-7.26854203,"NoSignifi"]
[1069,"KEGG_CELL_ADHESION_MOLECULES_CAMS",0.049355828,0.000244637,0.970116591,0.960640881,0.011523974,-7.268608324,"NoSignifi"]
[1068,"WP_TGFBETA_RECEPTOR_SIGNALING_IN_SKELETAL_DYSPLASIAS",0.046987967,0.000426517,0.97076741,0.962527722,-0.212793017,-7.268721906,"NoSignifi"]
[1067,"KEGG_PENTOSE_AND_GLUCURONATE_INTERCONVERSIONS",0.046665596,0.000537277,0.97076741,0.962784622,-0.099976558,-7.268736938,"NoSignifi"]
[1066,"REACTOME_NOTCH_HLH_TRANSCRIPTION_PATHWAY",0.042089684,0.000389137,0.973683116,0.966431596,-0.222575476,-7.268939146,"NoSignifi"]
[1065,"WP_HEDGEHOG_SIGNALING_PATHWAY_WP47",0.042043737,0.000481427,0.973683116,0.966468219,-0.101469496,-7.268941071,"NoSignifi"]
[1064,"WP_LET7_INHIBITION_OF_ES_CELL_REPROGRAMMING",0.040137795,0.000824958,0.974552311,0.967987459,-0.158458444,-7.269019056,"NoSignifi"]
[1063,"BIOCARTA_BTG2_PATHWAY",0.038893949,0.000532677,0.975219881,0.968978999,-0.141208351,-7.269068,"NoSignifi"]
[1062,"REACTOME_RUNX3_REGULATES_CDKN1A_TRANSCRIPTION",0.029655665,0.000444204,0.981302507,0.976344764,-0.306724373,-7.269383301,"NoSignifi"]
[1061,"BIOCARTA_AT1R_PATHWAY",0.008980063,0.000103937,0.994843675,0.992835979,-0.214821168,-7.269781019,"NoSignifi"]
[1060,"REACTOME_FLT3_SIGNALING_IN_DISEASE",0.008143477,{"v":9.68e-05,"d":"9.68E-05"},0.994843675,0.993503367,-0.227374283,-7.269788151,"NoSignifi"]
[1059,"REACTOME_OTHER_INTERLEUKIN_SIGNALING",0.005060362,{"v":4.84e-05,"d":"4.84E-05"},0.996592582,0.99596296,-0.067268911,-7.26980842,"NoSignifi"]
[1058,"REACTOME_SARS_COV_2_INFECTION",0.004955811,{"v":4.78e-05,"d":"4.78E-05"},0.996592582,0.996046368,-0.181395704,-7.269808941,"NoSignifi"]
[1057,"REACTOME_MITOCHONDRIAL_BIOGENESIS",-0.000423102,{"v":-3.64e-06,"d":"-3.64E-06"},0.999662458,0.999662458,-0.177568718,-7.26982108,"NoSignifi"]
[1056,"WP_INTERACTIONS_BETWEEN_LOXL4_AND_OXIDATIVE_STRESS_PATHWAY",-0.004691891,{"v":-6.5e-05,"d":"-6.50E-05"},0.996592582,0.996256916,-0.175126984,-7.269810209,"NoSignifi"]
[1055,"BIOCARTA_EIF_PATHWAY",-0.00822886,-0.000151393,0.994843675,0.993435252,-0.19088715,-7.269787455,"NoSignifi"]
[1053,"REACTOME_ORGANIC_CATION_ANION_ZWITTERION_TRANSPORT",-0.012813467,-0.000187506,0.992117059,0.989777948,0.085830757,-7.269739424,"NoSignifi"]
[1054,"REACTOME_ORGANIC_CATION_TRANSPORT",-0.012813467,-0.000187506,0.992117059,0.989777948,0.085830757,-7.269739424,"NoSignifi"]
[1052,"WP_COHESIN_COMPLEX_CORNELIA_DE_LANGE_SYNDROME",-0.016503028,-0.000170202,0.989835318,0.986834807,-0.202324672,-7.26968557,"NoSignifi"]
[1051,"REACTOME_DNA_REPLICATION_PRE_INITIATION",-0.017712431,-0.00022836,0.989201879,0.985870111,-0.135215291,-7.269664968,"NoSignifi"]
[1050,"REACTOME_RHOT1_GTPASE_CYCLE",-0.019973993,-0.00030065,0.987725677,0.984066202,-0.282046169,-7.269622533,"NoSignifi"]
[1049,"WP_HEPATITIS_C_AND_HEPATOCELLULAR_CARCINOMA",-0.022494852,-0.000193987,0.98604091,0.982055564,-0.165487079,-7.269569231,"NoSignifi"]
[1048,"REACTOME_RRNA_MODIFICATION_IN_THE_NUCLEUS_AND_CYTOSOL",-0.023992393,-0.000237247,0.985174844,0.980861179,-0.20889336,-7.26953457,"NoSignifi"]
[1047,"REACTOME_RECYCLING_OF_EIF2_GDP",-0.02886459,-0.000445379,0.981604247,0.976975598,-0.299835922,-7.26940635,"NoSignifi"]
[1046,"REACTOME_DISEASES_OF_SIGNAL_TRANSDUCTION_BY_GROWTH_FACTOR_RECEPTORS_AND_SECOND_MESSENGERS",-0.03141112,-0.000243264,0.980227414,0.974944949,-0.164968282,-7.269329927,"NoSignifi"]
[1045,"WP_DNA_DAMAGE_RESPONSE",-0.0318699,-0.000211254,0.980191541,0.974579127,-0.189908936,-7.269315473,"NoSignifi"]
[1044,"REACTOME_TGF_BETA_RECEPTOR_SIGNALING_ACTIVATES_SMADS",-0.036767173,-0.000460877,0.976595237,0.970674485,-0.211131688,-7.269148117,"NoSignifi"]
[1043,"REACTOME_THE_ROLE_OF_GTSE1_IN_G2_M_PROGRESSION_AFTER_G2_CHECKPOINT",-0.041496818,-0.000620712,0.973791876,0.96690416,-0.159665174,-7.268963819,"NoSignifi"]
[1042,"BIOCARTA_CTLA4_PATHWAY",-0.046495489,-0.000460623,0.97076741,0.962920183,0.096462554,-7.268744828,"NoSignifi"]
[1041,"WP_H19_ACTION_RBE2F1_SIGNALING_AND_CDKBETACATENIN_ACTIVITY",-0.046867648,-0.000670392,0.97076741,0.962623605,-0.255833163,-7.268727528,"NoSignifi"]
[1040,"REACTOME_COSTIMULATION_BY_THE_CD28_FAMILY",-0.048699917,-0.000313925,0.970314351,0.961163525,-0.106749933,-7.268640346,"NoSignifi"]
[1039,"REACTOME_IRF3_MEDIATED_INDUCTION_OF_TYPE_I_IFN",-0.053127793,-0.000802301,0.968069526,0.957635634,-0.231043245,-7.26841586,"NoSignifi"]
[1038,"REACTOME_AMINE_LIGAND_BINDING_RECEPTORS",-0.053216415,-0.000288854,0.968069526,0.957565033,0.424011819,-7.268411168,"NoSignifi"]
[1037,"KEGG_ENDOMETRIAL_CANCER",-0.059013097,-0.000493918,0.964315656,0.95294784,-0.206345178,-7.268087265,"NoSignifi"]
[1036,"WP_GASTRIC_CANCER_NETWORK_1",-0.060323179,-0.000439211,0.96424585,0.951904542,-0.007129717,-7.268009426,"NoSignifi"]
[1035,"PID_ERBB1_RECEPTOR_PROXIMAL_PATHWAY",-0.060979837,-0.000577509,0.964045079,0.951381637,-0.235498295,-7.267969767,"NoSignifi"]
[1034,"PID_SMAD2_3PATHWAY",-0.062558213,-0.000755984,0.963429184,0.95012484,-0.26398748,-7.267872685,"NoSignifi"]
[1033,"REACTOME_LIPOPHAGY",-0.067301412,-0.00101938,0.960256167,0.946348785,-0.171214729,-7.267566013,"NoSignifi"]
[1032,"REACTOME_RHOG_GTPASE_CYCLE",-0.069033101,-0.000569187,0.959513466,0.944970486,-0.173099366,-7.267448469,"NoSignifi"]
[1031,"REACTOME_DNA_DAMAGE_TELOMERE_STRESS_INDUCED_SENESCENCE",-0.070905987,-0.000583471,0.958327776,0.94347999,-0.221515092,-7.267317978,"NoSignifi"]
[1030,"KEGG_MISMATCH_REPAIR",-0.070933011,-0.000698397,0.958327776,0.943458485,-0.172565797,-7.26731607,"NoSignifi"]
[1029,"KEGG_PHENYLALANINE_METABOLISM",-0.07164557,-0.000922329,0.958327776,0.942891462,-0.077423413,-7.267265487,"NoSignifi"]
[1028,"REACTOME_ACYL_CHAIN_REMODELING_OF_CL",-0.077058889,-0.00167764,0.955316469,0.938584756,-0.212176313,-7.266864699,"NoSignifi"]
[1027,"REACTOME_PROTEIN_REPAIR",-0.081191908,-0.001647314,0.952624099,0.935297827,-0.198703827,-7.266539057,"NoSignifi"]
[1026,"REACTOME_SIGNALING_BY_CSF3_G_CSF",-0.08603321,-0.001165906,0.949355352,0.93144902,-0.117680624,-7.266135977,"NoSignifi"]
[1025,"BIOCARTA_S1P_PATHWAY",-0.088407775,-0.001291597,0.948139852,0.929561835,-0.277312543,-7.265929744,"NoSignifi"]
[1024,"REACTOME_TRIGLYCERIDE_BIOSYNTHESIS",-0.093558196,-0.001015909,0.94520818,0.925469915,-0.056077905,-7.265463127,"NoSignifi"]
[1023,"REACTOME_VISUAL_PHOTOTRANSDUCTION",-0.094112575,-0.000460658,0.945083566,0.925029587,0.036579715,-7.265411327,"NoSignifi"]
[1022,"REACTOME_MITOTIC_METAPHASE_AND_ANAPHASE",-0.097902136,-0.000864528,0.942333271,0.92202026,-0.136272972,-7.265049043,"NoSignifi"]
[1021,"REACTOME_THE_CANONICAL_RETINOID_CYCLE_IN_RODS_TWILIGHT_VISION",-0.10089528,-0.000734074,0.941079657,0.919644163,0.216267652,-7.264752788,"NoSignifi"]
[1020,"REACTOME_METABOLISM_OF_COFACTORS",-0.10114142,-0.001047852,0.941079657,0.919448797,-0.104554869,-7.264728029,"NoSignifi"]
[1019,"BIOCARTA_MCM_PATHWAY",-0.103981333,-0.001063361,0.939666024,0.917195062,-0.056297267,-7.264437997,"NoSignifi"]
[1018,"PID_TOLL_ENDOGENOUS_PATHWAY",-0.105080152,-0.001250327,0.939421151,0.916323225,-0.100778829,-7.264323624,"NoSignifi"]
[1017,"KEGG_SULFUR_METABOLISM",-0.107704173,-0.001166909,0.937934855,0.914241654,-0.009886127,-7.264045631,"NoSignifi"]
[1016,"PID_CDC42_PATHWAY",-0.110198679,-0.001063699,0.936228808,0.912263369,-0.193636325,-7.263775003,"NoSignifi"]
[1015,"REACTOME_CONSTITUTIVE_SIGNALING_BY_EGFRVIII",-0.11382426,-0.001410071,0.933924625,0.909389051,-0.255351327,-7.263370617,"NoSignifi"]
[1014,"REACTOME_NEGATIVE_REGULATION_OF_FGFR1_SIGNALING",-0.116165173,-0.001237889,0.932341848,0.90753383,-0.189754643,-7.263102565,"NoSignifi"]
[1013,"WP_SPHINGOLIPID_METABOLISM_IN_SENESCENCE",-0.117444577,-0.000990394,0.931945342,0.90652009,-0.225612616,-7.262953758,"NoSignifi"]
[1012,"KEGG_VIBRIO_CHOLERAE_INFECTION",-0.119614687,-0.001320714,0.930822593,0.904800944,-0.161694333,-7.262697625,"NoSignifi"]
[1011,"REACTOME_ACTIVATION_OF_BH3_ONLY_PROTEINS",-0.120808503,-0.001317821,0.930494691,0.903855402,-0.165439245,-7.262554723,"NoSignifi"]
[1010,"REACTOME_LATE_ENDOSOMAL_MICROAUTOPHAGY",-0.123425334,-0.00172657,0.929005727,0.901783263,-0.164652557,-7.262236518,"NoSignifi"]
[1009,"BIOCARTA_MAPK_PATHWAY",-0.12421533,-0.000889527,0.928683655,0.901157834,-0.246080918,-7.262139115,"NoSignifi"]
[1008,"KEGG_PYRUVATE_METABOLISM",-0.125139173,-0.001171745,0.9282522,0.90042652,-0.1775819,-7.262024421,"NoSignifi"]
[1007,"REACTOME_MRNA_SPLICING",-0.126005297,-0.001191619,0.928119146,0.899740972,-0.199096394,-7.261916121,"NoSignifi"]
[1006,"REACTOME_CELL_CYCLE",-0.127103489,-0.000757016,0.927615751,0.898871848,-0.14109043,-7.261777729,"NoSignifi"]
[1005,"WP_THYMIC_STROMAL_LYMPHOPOIETIN_TSLP_SIGNALING_PATHWAY",-0.128522845,-0.001041088,0.926778852,0.89774873,-0.168465289,-7.261597086,"NoSignifi"]
[1004,"REACTOME_VLDLR_INTERNALISATION_AND_DEGRADATION",-0.12872731,-0.001990376,0.926778852,0.897586956,-0.219914039,-7.261570898,"NoSignifi"]
[1003,"WP_EGFEGFR_SIGNALING_PATHWAY",-0.13414849,-0.000986758,0.92346989,0.893299267,-0.200090313,-7.260861371,"NoSignifi"]
[1002,"REACTOME_FATTY_ACIDS_BOUND_TO_GPR40_FFAR1_REGULATE_INSULIN_SECRETION",-0.134340947,-0.002280203,0.92346989,0.893147107,-0.134550923,-7.260835644,"NoSignifi"]
[1001,"WP_MONOAMINE_GPCRS",-0.136971197,-0.000743781,0.921805163,0.891067975,0.415215925,-7.260480348,"NoSignifi"]
[1000,"REACTOME_DOWNREGULATION_OF_ERBB2_SIGNALING",-0.13783766,-0.001762309,0.921533241,0.890383226,-0.159657196,-7.260361797,"NoSignifi"]
[999,"WP_NODLIKE_RECEPTOR_NLR_SIGNALING_PATHWAY",-0.146164834,-0.001965859,0.915569432,0.883806666,-0.26394967,-7.259184343,"NoSignifi"]
[998,"BIOCARTA_CSK_PATHWAY",-0.151787111,-0.001382184,0.911292168,0.879370853,0.028407816,-7.258350312,"NoSignifi"]
[997,"WP_TRANSCRIPTION_COFACTORS_SKI_AND_SKIL_PROTEIN_PARTNERS",-0.153580191,-0.001657789,0.910144623,0.877956955,-0.275020364,-7.2580777,"NoSignifi"]
[996,"REACTOME_ACTIVATED_NTRK2_SIGNALS_THROUGH_FYN",-0.15410433,-0.002950861,0.910033997,0.877543729,-0.082801235,-7.257997407,"NoSignifi"]
[995,"REACTOME_SPRY_REGULATION_OF_FGF_SIGNALING",-0.16118789,-0.002441045,0.905511185,0.871962438,-0.270654122,-7.25688545,"NoSignifi"]
[994,"REACTOME_GALACTOSE_CATABOLISM",-0.162195956,-0.002801749,0.905003426,0.871168674,-0.268781673,-7.256723146,"NoSignifi"]
[993,"REACTOME_ATF6_ATF6_ALPHA_ACTIVATES_CHAPERONE_GENES",-0.162196482,-0.003087493,0.905003426,0.871168259,-0.221797672,-7.256723061,"NoSignifi"]
[992,"REACTOME_ASSEMBLY_OF_ACTIVE_LPL_AND_LIPC_LIPASE_COMPLEXES",-0.162618242,-0.001699637,0.905003426,0.870836198,-0.016524599,-7.256654855,"NoSignifi"]
[991,"REACTOME_DARPP_32_EVENTS",-0.163402959,-0.001744421,0.904966209,0.870218433,-0.198220779,-7.25652748,"NoSignifi"]
[990,"REACTOME_ANDROGEN_BIOSYNTHESIS",-0.168771413,-0.001905675,0.9015207,0.865994287,0.08156566,-7.255639634,"NoSignifi"]
[989,"PID_IGF1_PATHWAY",-0.169066401,-0.001823126,0.9015207,0.865762286,-0.284900158,-7.255590017,"NoSignifi"]
[988,"WP_VEGFAVEGFR2_SIGNALING_PATHWAY",-0.169342291,-0.001448688,0.9015207,0.865545316,-0.16338772,-7.255543533,"NoSignifi"]
[987,"WP_RAS_SIGNALING",-0.169753205,-0.000889544,0.9015207,0.865222178,-0.120849485,-7.25547416,"NoSignifi"]
[986,"REACTOME_IMMUNOREGULATORY_INTERACTIONS_BETWEEN_A_LYMPHOID_AND_A_NON_LYMPHOID_CELL",-0.173902171,-0.001200499,0.8998458,0.861960746,0.127546064,-7.254764279,"NoSignifi"]
[985,"WP_GENE_REGULATORY_NETWORK_MODELLING_SOMITOGENESIS",-0.177095467,-0.002238126,0.897858351,0.85945215,0.093891048,-7.25420624,"NoSignifi"]
[984,"REACTOME_N_GLYCAN_TRIMMING_IN_THE_ER_AND_CALNEXIN_CALRETICULIN_CYCLE",-0.178626873,-0.002196223,0.896917664,0.858249607,-0.217267389,-7.253935019,"NoSignifi"]
[983,"REACTOME_RNA_POLYMERASE_III_TRANSCRIPTION_INITIATION_FROM_TYPE_1_PROMOTER",-0.185558494,-0.002040707,0.8915475,0.852810677,-0.208231216,-7.252678183,"NoSignifi"]
[982,"WP_MEVALONATE_PATHWAY",-0.186226691,-0.002915943,0.891313605,0.852286738,-0.267136649,-7.252554498,"NoSignifi"]
[981,"BIOCARTA_NTHI_PATHWAY",-0.186429318,-0.001919256,0.891313605,0.85212787,-0.193834046,-7.252516904,"NoSignifi"]
[980,"REACTOME_DIGESTION_AND_ABSORPTION",-0.190993851,-0.001425444,0.88865854,0.848550677,0.352568944,-7.251659184,"NoSignifi"]
[979,"REACTOME_SIGNALING_BY_CTNNB1_PHOSPHO_SITE_MUTANTS",-0.196288177,-0.002802803,0.885562821,0.844405463,-0.262663573,-7.250638342,"NoSignifi"]
[978,"REACTOME_PEPTIDE_HORMONE_METABOLISM",-0.197424382,-0.00133655,0.88494709,0.843516425,-0.056324928,-7.250415624,"NoSignifi"]
[977,"WP_LEPTIN_SIGNALING_PATHWAY",-0.200143195,-0.001645261,0.88334035,0.841389865,-0.197268706,-7.249877466,"NoSignifi"]
[976,"WP_PROTEASOME_DEGRADATION",-0.202957974,-0.003028027,0.881341888,0.839189464,-0.175228665,-7.249312558,"NoSignifi"]
[975,"REACTOME_EPH_EPHRIN_SIGNALING",-0.203986927,-0.002197668,0.88112081,0.838385412,-0.156785941,-7.249104084,"NoSignifi"]
[974,"REACTOME_HCMV_EARLY_EVENTS",-0.205443628,-0.001712581,0.880236372,0.837247395,-0.177531427,-7.248807144,"NoSignifi"]
[973,"KEGG_RENIN_ANGIOTENSIN_SYSTEM",-0.209042206,-0.002353772,0.877593013,0.834437547,-0.08038993,-7.248064536,"NoSignifi"]
[972,"REACTOME_SIGNALING_BY_ERBB2",-0.210078184,-0.002164901,0.877053355,0.833629023,-0.177343194,-7.24784836,"NoSignifi"]
[971,"WP_INHIBITION_OF_EXOSOME_BIOGENESIS_AND_SECRETION_BY_MANUMYCIN_A_IN_CRPC_CELLS",-0.210379688,-0.002404599,0.877053355,0.833393749,-0.256528979,-7.247785244,"NoSignifi"]
[970,"BIOCARTA_CK1_PATHWAY",-0.213952774,-0.002752233,0.874730117,0.830606686,-0.214651303,-7.247030381,"NoSignifi"]
[969,"REACTOME_CELL_SURFACE_INTERACTIONS_AT_THE_VASCULAR_WALL",-0.221755322,-0.001217949,0.870253722,0.82452803,-0.011417542,-7.245337798,"NoSignifi"]
[968,"REACTOME_NEGATIVE_REGULATION_OF_FLT3",-0.228413326,-0.003422714,0.867563551,0.819349342,-0.15855238,-7.243845566,"NoSignifi"]
[967,"PID_RHOA_PATHWAY",-0.231392957,-0.002842122,0.8654209,0.817034282,-0.127089365,-7.243163456,"NoSignifi"]
[966,"BIOCARTA_IRES_PATHWAY",-0.245974568,-0.005259945,0.855582025,0.805728306,-0.239966596,-7.239697891,"NoSignifi"]
[965,"SIG_INSULIN_RECEPTOR_PATHWAY_IN_CARDIAC_MYOCYTES",-0.246359615,-0.00235979,0.855571574,0.805430296,-0.241423289,-7.239603509,"NoSignifi"]
[964,"PID_ARF6_TRAFFICKING_PATHWAY",-0.24693495,-0.002255003,0.855404671,0.804985063,-0.173017181,-7.239462209,"NoSignifi"]
[963,"BIOCARTA_CTL_PATHWAY",-0.253850402,-0.002607107,0.850768528,0.799638412,0.318704632,-7.237738013,"NoSignifi"]
[962,"KEGG_BASE_EXCISION_REPAIR",-0.254190483,-0.002212191,0.850768528,0.799375721,-0.171131425,-7.237651995,"NoSignifi"]
[961,"REACTOME_GLUTAMATE_NEUROTRANSMITTER_RELEASE_CYCLE",-0.257457267,-0.002673365,0.849500183,0.796853489,-0.103683802,-7.236819837,"NoSignifi"]
[960,"REACTOME_ACTIVATION_OF_NOXA_AND_TRANSLOCATION_TO_MITOCHONDRIA",-0.260486585,-0.004959412,0.847617491,0.794516496,-0.281117721,-7.236038676,"NoSignifi"]
[959,"REACTOME_IRE1ALPHA_ACTIVATES_CHAPERONES",-0.260604831,-0.002533034,0.847617491,0.794425312,-0.215184479,-7.236007999,"NoSignifi"]
[958,"WP_NAD_METABOLISM_SIRTUINS_AND_AGING",-0.269642644,-0.003386259,0.841605982,0.78746427,-0.276079253,-7.233622085,"NoSignifi"]
[957,"REACTOME_INTERLEUKIN_3_INTERLEUKIN_5_AND_GM_CSF_SIGNALING",-0.270673891,-0.002382872,0.841060991,0.786671059,-0.127394494,-7.233344675,"NoSignifi"]
[956,"REACTOME_M_PHASE",-0.273376928,-0.002066278,0.839305262,0.784592996,-0.141769026,-7.232612519,"NoSignifi"]
[955,"REACTOME_ACTIVATION_OF_TRKA_RECEPTORS",-0.279398477,-0.006374324,0.835399956,0.779969242,-0.078344862,-7.230955345,"NoSignifi"]
[954,"REACTOME_RAC2_GTPASE_CYCLE",-0.280317681,-0.002143801,0.835247328,0.779264095,-0.182469569,-7.230699197,"NoSignifi"]
[953,"PID_MTOR_4PATHWAY",-0.284898895,-0.002917844,0.831783675,0.775752441,-0.219921727,-7.22941004,"NoSignifi"]
[952,"BIOCARTA_PTDINS_PATHWAY",-0.294529127,-0.003571403,0.82507658,0.768385565,-0.188646382,-7.226631953,"NoSignifi"]
[951,"REACTOME_CASPASE_MEDIATED_CLEAVAGE_OF_CYTOSKELETAL_PROTEINS",-0.297887579,-0.004626922,0.823514482,0.765821315,-0.168795616,-7.225641406,"NoSignifi"]
[950,"REACTOME_GLUCAGON_LIKE_PEPTIDE_1_GLP1_REGULATES_INSULIN_SECRETION",-0.301509778,-0.002969094,0.821436142,0.763058565,-0.096921399,-7.224560481,"NoSignifi"]
[949,"KEGG_SNARE_INTERACTIONS_IN_VESICULAR_TRANSPORT",-0.302609371,-0.002189357,0.821129382,0.76222047,-0.247546962,-7.22422976,"NoSignifi"]
[948,"REACTOME_MAPK_TARGETS_NUCLEAR_EVENTS_MEDIATED_BY_MAP_KINASES",-0.304380966,-0.00291115,0.820568589,0.760870773,-0.23999716,-7.22369439,"NoSignifi"]
[947,"REACTOME_NUCLEAR_IMPORT_OF_REV_PROTEIN",-0.305977528,-0.00270184,0.819555175,0.759655049,-0.218895058,-7.223209237,"NoSignifi"]
[946,"REACTOME_RIP_MEDIATED_NFKB_ACTIVATION_VIA_ZBP1",-0.306165932,-0.003042863,0.819555175,0.759511625,-0.196147294,-7.223151819,"NoSignifi"]
[945,"REACTOME_HOST_INTERACTIONS_OF_HIV_FACTORS",-0.313037402,-0.00364075,0.815433357,0.754286369,-0.134055465,-7.221033508,"NoSignifi"]
[944,"WP_FLUOROACETIC_ACID_TOXICITY",-0.315486693,-0.005457463,0.813889568,0.752426564,-0.23694951,-7.220267085,"NoSignifi"]
[943,"WP_RELATIONSHIP_BETWEEN_INFLAMMATION_COX2_AND_EGFR",-0.315676509,-0.002717526,0.813889568,0.752282492,-0.240883399,-7.220207439,"NoSignifi"]
[942,"REACTOME_RHOH_GTPASE_CYCLE",-0.31593129,-0.003112247,0.813889568,0.752089125,-0.19231905,-7.220127323,"NoSignifi"]
[941,"REACTOME_THE_ROLE_OF_NEF_IN_HIV_1_REPLICATION_AND_DISEASE_PATHOGENESIS",-0.320235397,-0.003587657,0.811409132,0.748824864,-0.105433483,-7.218764122,"NoSignifi"]
[940,"WP_NUCLEOTIDE_METABOLISM",-0.321215244,-0.003842548,0.810900531,0.748082369,-0.196838312,-7.218451207,"NoSignifi"]
[939,"REACTOME_MAP3K8_TPL2_DEPENDENT_MAPK1_3_ACTIVATION",-0.325375442,-0.005254965,0.808549338,0.744932521,-0.200238448,-7.217111998,"NoSignifi"]
[938,"WP_MRNA_PROCESSING",-0.329507767,-0.003463072,0.805864596,0.741807997,-0.180812156,-7.215764703,"NoSignifi"]
[937,"KEGG_MAPK_SIGNALING_PATHWAY",-0.333913382,-0.001641382,0.803426761,0.738481519,-0.160133688,-7.214309581,"NoSignifi"]
[936,"BIOCARTA_NPC_PATHWAY",-0.335804237,-0.004693381,0.802757609,0.737055319,-0.181993137,-7.213679128,"NoSignifi"]
[935,"WP_ALTERED_GLYCOSYLATION_OF_MUC1_IN_TUMOR_MICROENVIRONMENT",-0.33651843,-0.004418711,0.802465531,0.736516865,-0.12128555,-7.213440074,"NoSignifi"]
[934,"BIOCARTA_STATHMIN_PATHWAY",-0.341640041,-0.003120286,0.800065942,0.732659323,0.027202264,-7.211710893,"NoSignifi"]
[933,"REACTOME_ACTIVATION_OF_NIMA_KINASES_NEK9_NEK6_NEK7",-0.34254728,-0.004319723,0.799867068,0.7319767,-0.11050275,-7.211401865,"NoSignifi"]
[932,"REACTOME_SUMOYLATION_OF_CHROMATIN_ORGANIZATION_PROTEINS",-0.3457291,-0.002499056,0.79813407,0.729584326,-0.218964962,-7.210311579,"NoSignifi"]
[931,"REACTOME_GASTRIN_CREB_SIGNALLING_PATHWAY_VIA_PKC_AND_MAPK",-0.347244129,-0.004206694,0.797182647,0.728446117,-0.25487988,-7.209788896,"NoSignifi"]
[930,"PID_ERA_GENOMIC_PATHWAY",-0.348196595,-0.002872683,0.796693551,0.727730856,-0.199640939,-7.209459126,"NoSignifi"]
[929,"PID_P53_REGULATION_PATHWAY",-0.34824469,-0.003114682,0.796693551,0.727694745,-0.227010521,-7.209442451,"NoSignifi"]
[928,"REACTOME_TRANSCRIPTIONAL_ACTIVATION_OF_MITOCHONDRIAL_BIOGENESIS",-0.348348244,-0.002630188,0.796693551,0.727616995,-0.193380905,-7.209406538,"NoSignifi"]
[927,"REACTOME_SIGNALING_BY_ERBB2_IN_CANCER",-0.352560129,-0.003699998,0.793987833,0.72445707,-0.180028533,-7.207936805,"NoSignifi"]
[926,"KEGG_PROXIMAL_TUBULE_BICARBONATE_RECLAMATION",-0.352876147,-0.003726218,0.793987833,0.72422017,-0.116968829,-7.207825819,"NoSignifi"]
[925,"KEGG_PROSTATE_CANCER",-0.35947907,-0.002906684,0.789475658,0.719276407,-0.214342265,-7.205484111,"NoSignifi"]
[924,"REACTOME_TFAP2A_ACTS_AS_A_TRANSCRIPTIONAL_REPRESSOR_DURING_RETINOIC_ACID_INDUCED_CELL_DIFFERENTIATION",-0.36060017,-0.00731616,0.78884724,0.718438173,-0.045856731,-7.205082206,"NoSignifi"]
[923,"KEGG_PATHWAYS_IN_CANCER",-0.366562896,-0.002064789,0.78453861,0.713985626,-0.144947481,-7.202923591,"NoSignifi"]
[922,"BIOCARTA_PGC1A_PATHWAY",-0.368228005,-0.004612017,0.783464216,0.71274397,-0.126654498,-7.202314468,"NoSignifi"]
[921,"KEGG_ERBB_SIGNALING_PATHWAY",-0.368814755,-0.002350255,0.783464216,0.712306618,-0.205861807,-7.202099169,"NoSignifi"]
[920,"BIOCARTA_RHO_PATHWAY",-0.368882113,-0.004632335,0.783464216,0.712256416,-0.151440731,-7.202074431,"NoSignifi"]
[919,"BIOCARTA_CACAM_PATHWAY",-0.372615378,-0.005808129,0.781028643,0.709476002,-0.065333658,-7.200696283,"NoSignifi"]
[918,"REACTOME_SUMOYLATION_OF_SUMOYLATION_PROTEINS",-0.382940954,-0.003284489,0.773732744,0.701806089,-0.21484543,-7.1968123,"NoSignifi"]
[917,"REACTOME_RAS_PROCESSING",-0.385401445,-0.005696037,0.772561633,0.69998286,-0.202148636,-7.195871122,"NoSignifi"]
[916,"REACTOME_VEGFR2_MEDIATED_VASCULAR_PERMEABILITY",-0.385499117,-0.004680211,0.772561633,0.69991052,-0.209452615,-7.195833636,"NoSignifi"]
[915,"PID_NCADHERIN_PATHWAY",-0.385516489,-0.004722176,0.772561633,0.699897654,-0.165024528,-7.195826969,"NoSignifi"]
[914,"WP_MIRNA_REGULATION_OF_PROSTATE_CANCER_SIGNALING_PATHWAYS",-0.385688942,-0.003849467,0.772561633,0.699769937,-0.25102983,-7.195760757,"NoSignifi"]
[913,"REACTOME_SEPARATION_OF_SISTER_CHROMATIDS",-0.386728654,-0.003607928,0.772561633,0.699000113,-0.139483529,-7.195360941,"NoSignifi"]
[912,"WP_HEMATOPOIETIC_STEM_CELL_GENE_REGULATION_BY_GABP_ALPHABETA_COMPLEX",-0.389507304,-0.004431574,0.770662018,0.696944264,-0.249528416,-7.194287144,"NoSignifi"]
[911,"REACTOME_RND2_GTPASE_CYCLE",-0.390542792,-0.003579913,0.770102298,0.696178703,-0.186056875,-7.193885019,"NoSignifi"]
[910,"BIOCARTA_TGFB_PATHWAY",-0.394133508,-0.004625157,0.7674543,0.693526402,-0.311138171,-7.192482318,"NoSignifi"]
[909,"WP_GLUTATHIONE_METABOLISM",-0.400225208,-0.003977783,0.763053305,0.689035335,-0.09768448,-7.190073256,"NoSignifi"]
[908,"WP_FRAGILE_X_SYNDROME",-0.403696997,-0.002772001,0.760791751,0.686480667,-0.143394988,-7.188683754,"NoSignifi"]
[907,"BIOCARTA_FMLP_PATHWAY",-0.404844458,-0.003673116,0.760140619,0.685637109,-0.165019157,-7.188221871,"NoSignifi"]
[906,"BIOCARTA_ACTINY_PATHWAY",-0.406017642,-0.00589494,0.759716082,0.684775047,-0.121782599,-7.187748279,"NoSignifi"]
[905,"REACTOME_LOSS_OF_FUNCTION_OF_MECP2_IN_RETT_SYNDROME",-0.406168883,-0.005002349,0.759716082,0.684663944,-0.270072679,-7.187687126,"NoSignifi"]
[904,"WP_MALIGNANT_PLEURAL_MESOTHELIOMA",-0.409295612,-0.00207389,0.757648556,0.682368555,-0.12349296,-7.186417763,"NoSignifi"]
[903,"PID_ER_NONGENOMIC_PATHWAY",-0.413463942,-0.004205849,0.755103156,0.679313078,-0.182844591,-7.184710403,"NoSignifi"]
[902,"BIOCARTA_TEL_PATHWAY",-0.413691483,-0.005228284,0.755103156,0.679146436,-0.250581891,-7.184616703,"NoSignifi"]
[901,"WP_INTERACTIONS_BETWEEN_IMMUNE_CELLS_AND_MICRORNAS_IN_TUMOR_MICROENVIRONMENT",-0.417847097,-0.00357225,0.752101215,0.676105808,-0.088816425,-7.182896393,"NoSignifi"]
[900,"WP_MITOCHONDRIAL_FATTY_ACID_SYNTHESIS_PATHWAY",-0.419156125,-0.007880057,0.751318463,0.675149094,-0.237852599,-7.18235093,"NoSignifi"]
[899,"REACTOME_HIV_INFECTION",-0.421291377,-0.00397871,0.750426898,0.673589654,-0.164774841,-7.181457525,"NoSignifi"]
[898,"REACTOME_MITOTIC_PROMETAPHASE",-0.422137486,-0.002584528,0.750020336,0.672972103,-0.123112945,-7.181102252,"NoSignifi"]
[897,"PID_IL2_1PATHWAY",-0.424027457,-0.003361446,0.748764924,0.671593463,-0.223005361,-7.180306096,"NoSignifi"]
[896,"PID_P38_MK2_PATHWAY",-0.425356631,-0.005887629,0.747965557,0.670624558,-0.245614696,-7.179744048,"NoSignifi"]
[895,"REACTOME_S_PHASE",-0.428233758,-0.003905826,0.745908696,0.668529147,-0.159020908,-7.178521416,"NoSignifi"]
[894,"BIOCARTA_ACH_PATHWAY",-0.432305411,-0.005630912,0.743443161,0.665568179,-0.168158782,-7.176777089,"NoSignifi"]
[893,"BIOCARTA_PPARG_PATHWAY",-0.436447884,-0.006751822,0.740362729,0.662561054,-0.262076899,-7.174985486,"NoSignifi"]
[892,"PID_AP1_PATHWAY",-0.437499755,-0.004372525,0.739788881,0.661798339,-0.167912579,-7.174527836,"NoSignifi"]
[891,"REACTOME_POLB_DEPENDENT_LONG_PATCH_BASE_EXCISION_REPAIR",-0.441826431,-0.007837256,0.737118597,0.658664748,-0.245817509,-7.172633797,"NoSignifi"]
[890,"PID_P38_ALPHA_BETA_PATHWAY",-0.442921118,-0.004706506,0.736510012,0.65787287,-0.162954126,-7.172151634,"NoSignifi"]
[889,"KEGG_AMINOACYL_TRNA_BIOSYNTHESIS",-0.446852114,-0.004477222,0.734507468,0.655032422,-0.118438125,-7.170410367,"NoSignifi"]
[888,"PID_RB_1PATHWAY",-0.458351419,-0.003194636,0.72597612,0.64675205,-0.244134064,-7.165228338,"NoSignifi"]
[887,"REACTOME_ASSEMBLY_OF_THE_HIV_VIRION",-0.465129403,-0.008269324,0.721611717,0.64189173,-0.190746644,-7.162112259,"NoSignifi"]
[886,"PID_RET_PATHWAY",-0.468092925,-0.004576525,0.719500557,0.639771462,-0.246137256,-7.160735454,"NoSignifi"]
[885,"REACTOME_TIGHT_JUNCTION_INTERACTIONS",-0.470921995,-0.003372199,0.717499106,0.637750132,0.120318581,-7.159412957,"NoSignifi"]
[884,"BIOCARTA_HBX_PATHWAY",-0.471939814,-0.007996584,0.716953368,0.637023572,-0.378122555,-7.158935212,"NoSignifi"]
[883,"WP_CARDIAC_PROGENITOR_DIFFERENTIATION",-0.474020576,-0.003717108,0.715825595,0.635539329,-0.057130446,-7.157955331,"NoSignifi"]
[882,"REACTOME_SIGNALLING_TO_ERKS",-0.474958213,-0.004484333,0.715632302,0.634870975,-0.235681334,-7.157512367,"NoSignifi"]
[881,"WP_CLASSICAL_PATHWAY_OF_STEROIDOGENESIS_WITH_GLUCOCORTICOID_AND_MINERALOCORTICOID_METABOLISM",-0.480748431,-0.006843507,0.711781671,0.630750279,0.00892136,-7.154757528,"NoSignifi"]
[880,"REACTOME_BH3_ONLY_PROTEINS_ASSOCIATE_WITH_AND_INACTIVATE_ANTI_APOPTOTIC_BCL_2_MEMBERS",-0.49916124,-0.006932165,0.700274975,0.617723193,-0.158345706,-7.145775384,"NoSignifi"]
[879,"WP_FOXA2_PATHWAY",-0.501070534,-0.004460559,0.699018197,0.616379131,0.093543149,-7.14482468,"NoSignifi"]
[878,"REACTOME_ADHERENS_JUNCTIONS_INTERACTIONS",-0.503973907,-0.005334899,0.697235767,0.614337745,-0.174609014,-7.143372036,"NoSignifi"]
[877,"REACTOME_ATTENUATION_PHASE",-0.504366041,-0.006909695,0.697189619,0.614062261,-0.186934314,-7.143175197,"NoSignifi"]
[876,"REACTOME_HIV_LIFE_CYCLE",-0.505251059,-0.003936275,0.697017022,0.613440714,-0.191323314,-7.142730382,"NoSignifi"]
[875,"REACTOME_TP53_REGULATES_METABOLIC_GENES",-0.50667826,-0.005247746,0.696145224,0.612438978,-0.163586372,-7.142011421,"NoSignifi"]
[874,"REACTOME_FORMYL_PEPTIDE_RECEPTORS_BIND_FORMYL_PEPTIDES_AND_MANY_OTHER_LIGANDS",-0.50668995,-0.008271892,0.696145224,0.612430776,0.036848705,-7.142005523,"NoSignifi"]
[873,"BIOCARTA_MRP_PATHWAY",-0.509910476,-0.009820589,0.694101013,0.610173003,-0.126756683,-7.140375676,"NoSignifi"]
[872,"WP_TRANSLATION_INHIBITORS_IN_CHRONICALLY_ACTIVATED_PDGFRA_CELLS",-0.510106961,-0.004631977,0.694101013,0.610035375,-0.227548298,-7.140275904,"NoSignifi"]
[871,"WP_MAPK_SIGNALING_PATHWAY",-0.512607627,-0.002648061,0.693463639,0.608284996,-0.160994549,-7.139002755,"NoSignifi"]
[870,"PID_ERBB1_DOWNSTREAM_PATHWAY",-0.514692418,-0.005050966,0.692151609,0.606827429,-0.187994467,-7.137936581,"NoSignifi"]
[869,"BIOCARTA_PELP1_PATHWAY",-0.521616333,-0.008773181,0.687435261,0.601997871,-0.274706753,-7.134364606,"NoSignifi"]
[868,"REACTOME_REGULATION_OF_CYTOSKELETAL_REMODELING_AND_CELL_SPREADING_BY_IPP_COMPLEX_COMPONENTS",-0.528023218,-0.00886612,0.682875099,0.597544461,-0.190443848,-7.131016856,"NoSignifi"]
[867,"WP_MIRNA_REGULATION_OF_DNA_DAMAGE_RESPONSE",-0.528854151,-0.003455173,0.68247899,0.596967981,-0.196448891,-7.130579681,"NoSignifi"]
[866,"REACTOME_GOLGI_ASSOCIATED_VESICLE_BIOGENESIS",-0.528926053,-0.005490188,0.68247899,0.59691811,-0.171587243,-7.130541819,"NoSignifi"]
[865,"REACTOME_INTRA_GOLGI_AND_RETROGRADE_GOLGI_TO_ER_TRAFFIC",-0.529064799,-0.003529273,0.68247899,0.596821879,-0.160459674,-7.130468744,"NoSignifi"]
[864,"BIOCARTA_AKAP95_PATHWAY",-0.531406016,-0.007374474,0.682032524,0.595199148,-0.202944926,-7.129232783,"NoSignifi"]
[863,"REACTOME_APC_C_CDH1_MEDIATED_DEGRADATION_OF_CDC20_AND_OTHER_APC_C_CDH1_TARGETED_PROTEINS_IN_LATE_MITOSIS_EARLY_G1",-0.531518963,-0.007232704,0.682032524,0.595120913,-0.159665947,-7.129173018,"NoSignifi"]
[862,"REACTOME_DISASSEMBLY_OF_THE_DESTRUCTION_COMPLEX_AND_RECRUITMENT_OF_AXIN_TO_THE_MEMBRANE",-0.535304282,-0.005565735,0.679728556,0.592501685,-0.199996683,-7.127162728,"NoSignifi"]
[861,"REACTOME_REGULATION_OF_LIPID_METABOLISM_BY_PPARALPHA",-0.543146671,-0.002935351,0.674826342,0.587092099,-0.23562818,-7.122952446,"NoSignifi"]
[860,"BIOCARTA_TALL1_PATHWAY",-0.5556917,-0.005703788,0.667000678,0.57848661,-0.118473193,-7.116090215,"NoSignifi"]
[859,"REACTOME_NUCLEAR_ENVELOPE_NE_REASSEMBLY",-0.556828206,-0.004341991,0.666363956,0.577709943,-0.147175571,-7.115460799,"NoSignifi"]
[858,"WP_NIPBL_ROLE_IN_DNA_DAMAGE_CORNELIA_DE_LANGE_SYNDROME",-0.557329465,-0.009405605,0.666363956,0.577367549,-0.236431117,-7.115182785,"NoSignifi"]
[857,"PID_SMAD2_3NUCLEAR_PATHWAY",-0.558335567,-0.004560028,0.665952821,0.5766806,-0.211802316,-7.114624014,"NoSignifi"]
[856,"REACTOME_SYNTHESIS_SECRETION_AND_INACTIVATION_OF_GLUCOSE_DEPENDENT_INSULINOTROPIC_POLYPEPTIDE_GIP",-0.55870572,-0.010944611,0.665920087,0.576427964,-0.099461778,-7.114418185,"NoSignifi"]
[855,"WP_TRANSSULFURATION_AND_ONECARBON_METABOLISM",-0.56008615,-0.004239532,0.665349956,0.575486254,-0.110801623,-7.113649371,"NoSignifi"]
[854,"REACTOME_SYNTHESIS_OF_DNA",-0.563550067,-0.006157569,0.663138098,0.573126427,-0.132722277,-7.111711835,"NoSignifi"]
[853,"BIOCARTA_ERK5_PATHWAY",-0.566806953,-0.007000122,0.661090973,0.57091184,-0.30316022,-7.109879208,"NoSignifi"]
[852,"REACTOME_CELL_CYCLE_MITOTIC",-0.567030479,-0.00363141,0.661090973,0.570759999,-0.135580731,-7.109753044,"NoSignifi"]
[851,"REACTOME_RHOV_GTPASE_CYCLE",-0.572127866,-0.006795415,0.657424411,0.567302574,-0.149044497,-7.106862454,"NoSignifi"]
[850,"REACTOME_DISEASES_OF_PROGRAMMED_CELL_DEATH",-0.574898362,-0.005562778,0.655507482,0.565427639,-0.118086696,-7.105280534,"NoSignifi"]
[849,"REACTOME_GOLGI_CISTERNAE_PERICENTRIOLAR_STACK_REORGANIZATION",-0.577108326,-0.007913055,0.654031483,0.563934185,-0.210334365,-7.104013194,"NoSignifi"]
[848,"REACTOME_TRANSPORT_OF_CONNEXONS_TO_THE_PLASMA_MEMBRANE",-0.5785285,-0.008555983,0.65343008,0.562975461,-0.126345891,-7.103196206,"NoSignifi"]
[847,"REACTOME_APC_C_MEDIATED_DEGRADATION_OF_CELL_CYCLE_PROTEINS",-0.587235536,-0.007203571,0.647640533,0.557114827,-0.14297039,-7.098143405,"NoSignifi"]
[846,"REACTOME_TAK1_ACTIVATES_NFKB_BY_PHOSPHORYLATION_AND_ACTIVATION_OF_IKKS_COMPLEX",-0.592005502,-0.006459111,0.644680187,0.55391686,-0.121409597,-7.095343345,"NoSignifi"]
[845,"REACTOME_HSP90_CHAPERONE_CYCLE_FOR_STEROID_HORMONE_RECEPTORS_SHR_IN_THE_PRESENCE_OF_LIGAND",-0.59563968,-0.007182065,0.642592973,0.551486421,-0.16224487,-7.093194816,"NoSignifi"]
[844,"WP_ENDOPLASMIC_RETICULUM_STRESS_RESPONSE_IN_CORONAVIRUS_INFECTION",-0.602068473,-0.004844161,0.638113324,0.547199907,-0.155940664,-7.089361917,"NoSignifi"]
[843,"REACTOME_RHOU_GTPASE_CYCLE",-0.609993378,-0.0061586,0.632723487,0.541938642,-0.200154876,-7.084580421,"NoSignifi"]
[842,"WP_BASE_EXCISION_REPAIR",-0.623054585,-0.005570177,0.624137071,0.53332292,-0.178214238,-7.076563543,"NoSignifi"]
[841,"PID_GLYPICAN_1PATHWAY",-0.629578969,-0.006732018,0.620795924,0.529045266,-0.151233478,-7.072495338,"NoSignifi"]
[840,"REACTOME_ABACAVIR_METABOLISM",-0.630023009,-0.013071613,0.620748484,0.528754771,-0.235757166,-7.072216922,"NoSignifi"]
[839,"REACTOME_INACTIVATION_OF_CSF3_G_CSF_SIGNALING",-0.630587427,-0.00934367,0.620560511,0.528385642,-0.087860097,-7.071862746,"NoSignifi"]
[838,"WP_NAD_METABOLISM_IN_ONCOGENEINDUCED_SENESCENCE_AND_MITOCHONDRIAL_DYSFUNCTIONASSOCIATED_SENESCENCE",-0.63215957,-0.005572964,0.619598875,0.527358153,-0.202906085,-7.070874543,"NoSignifi"]
[837,"BIOCARTA_SKP2E2F_PATHWAY",-0.632868628,-0.008379919,0.619299873,0.526895075,-0.150177481,-7.070428045,"NoSignifi"]
[836,"REACTOME_BETA_OXIDATION_OF_BUTANOYL_COA_TO_ACETYL_COA",-0.634510737,-0.011577531,0.618775175,0.525823431,-0.193597317,-7.069392078,"NoSignifi"]
[835,"REACTOME_FORMATION_OF_APOPTOSOME",-0.642596884,-0.008556413,0.614288824,0.520562708,-0.233658132,-7.064251584,"NoSignifi"]
[834,"WP_INTEGRINMEDIATED_CELL_ADHESION",-0.6448791,-0.004832902,0.613029837,0.51908286,-0.160048422,-7.062788969,"NoSignifi"]
[833,"WP_MALE_INFERTILITY",-0.645323317,-0.003243243,0.613029837,0.518795071,-0.077485806,-7.062503679,"NoSignifi"]
[832,"REACTOME_NEF_MEDIATES_DOWN_MODULATION_OF_CELL_SURFACE_RECEPTORS_BY_RECRUITING_THEM_TO_CLATHRIN_ADAPTERS",-0.647688297,-0.008215451,0.611855652,0.517264293,-0.179953457,-7.060981509,"NoSignifi"]
[831,"WP_MEASLES_VIRUS_INFECTION",-0.64942851,-0.004127342,0.611255641,0.516139404,-0.142689622,-7.059857902,"NoSignifi"]
[830,"BIOCARTA_MONOCYTE_PATHWAY",-0.653913293,-0.005887609,0.60855757,0.513246263,0.232006936,-7.056948313,"NoSignifi"]
[829,"REACTOME_REGULATION_OF_CHOLESTEROL_BIOSYNTHESIS_BY_SREBP_SREBF",-0.663711704,-0.004789929,0.602059547,0.506954822,-0.266267265,-7.050521773,"NoSignifi"]
[828,"REACTOME_TRNA_PROCESSING_IN_THE_MITOCHONDRION",-0.666661969,-0.013469032,0.600539961,0.505068468,-0.244280422,-7.048568053,"NoSignifi"]
[827,"PID_IL8_CXCR2_PATHWAY",-0.669796566,-0.00598146,0.598401375,0.503068317,-0.070537939,-7.046482774,"NoSignifi"]
[826,"WP_BIOMARKERS_FOR_UREA_CYCLE_DISORDERS",-0.679995707,-0.007616869,0.591880407,0.496589456,0.091440994,-7.039630175,"NoSignifi"]
[825,"REACTOME_GLUCAGON_TYPE_LIGAND_RECEPTORS",-0.687278381,-0.008041252,0.587106179,0.491990628,-0.044619059,-7.034673749,"NoSignifi"]
[824,"WP_GENES_TARGETED_BY_MIRNAS_IN_ADIPOCYTES",-0.687754016,-0.007772891,0.58698464,0.491691074,0.008143539,-7.034348207,"NoSignifi"]
[823,"KEGG_GLYOXYLATE_AND_DICARBOXYLATE_METABOLISM",-0.688588638,-0.008781941,0.586593269,0.491165667,-0.215206689,-7.033776416,"NoSignifi"]
[822,"BIOCARTA_TERT_PATHWAY",-0.693241209,-0.010613047,0.583336628,0.488242345,-0.316801103,-7.030576287,"NoSignifi"]
[821,"PID_EPHB_FWD_PATHWAY",-0.693956656,-0.007302384,0.583065187,0.487793647,-0.193184221,-7.030082279,"NoSignifi"]
[820,"BIOCARTA_ACETAMINOPHEN_PATHWAY",-0.694915111,-0.009629635,0.582786342,0.487192893,-0.042537039,-7.029419677,"NoSignifi"]
[819,"PID_UPA_UPAR_PATHWAY",-0.695143783,-0.006813952,0.582786342,0.487049623,-0.07742552,-7.029261456,"NoSignifi"]
[818,"PID_ERBB2_ERBB3_PATHWAY",-0.695314999,-0.006561719,0.582786342,0.486942364,-0.206892722,-7.029142954,"NoSignifi"]
[817,"KEGG_RENAL_CELL_CARCINOMA",-0.706209607,-0.00628558,0.576211365,0.480143792,-0.211419422,-7.021542684,"NoSignifi"]
[816,"WP_FERROPTOSIS",-0.717533777,-0.006637222,0.56894699,0.473132407,-0.17236371,-7.01351757,"NoSignifi"]
[815,"REACTOME_TRANSPORT_OF_MATURE_TRANSCRIPT_TO_CYTOPLASM",-0.720306166,-0.00555321,0.568043573,0.471424508,-0.230670037,-7.011533415,"NoSignifi"]
[814,"REACTOME_ENERGY_DEPENDENT_REGULATION_OF_MTOR_BY_LKB1_AMPK",-0.721110162,-0.00711939,0.567908502,0.470929852,-0.194367623,-7.010956577,"NoSignifi"]
[813,"REACTOME_INFLAMMASOMES",-0.721700464,-0.00812639,0.567701337,0.470566854,-0.145283322,-7.010532648,"NoSignifi"]
[812,"KEGG_ENDOCYTOSIS",-0.722260723,-0.004646819,0.567516472,0.470222473,-0.170855104,-7.010129973,"NoSignifi"]
[811,"BIOCARTA_NKCELLS_PATHWAY",-0.722474344,-0.010609881,0.567516472,0.470091201,-0.156440982,-7.009976355,"NoSignifi"]
[810,"WP_IL18_SIGNALING_PATHWAY",-0.731323433,-0.003747215,0.561958759,0.464671187,-0.113094425,-7.003572953,"NoSignifi"]
[809,"WP_VITAMIN_A_AND_CAROTENOID_METABOLISM",-0.735096363,-0.005058916,0.559632792,0.462370912,0.046008351,-7.000819085,"NoSignifi"]
[808,"REACTOME_DOWNREGULATION_OF_SMAD2_3_SMAD4_TRANSCRIPTIONAL_ACTIVITY",-0.738991276,-0.009284945,0.557221039,0.460002953,-0.267216902,-6.997961324,"NoSignifi"]
[807,"WP_BRAINDERIVED_NEUROTROPHIC_FACTOR_BDNF_SIGNALING_PATHWAY",-0.739751679,-0.005139524,0.557116604,0.45954145,-0.169290962,-6.997401643,"NoSignifi"]
[806,"BIOCARTA_RNAPOL3_PATHWAY",-0.745785624,-0.011638611,0.553139806,0.45588855,-0.205854075,-6.992940072,"NoSignifi"]
[805,"WP_RAS_AND_BRADYKININ_PATHWAYS_IN_COVID19",-0.747060706,-0.005931217,0.552883589,0.455118724,0.068910832,-6.991992625,"NoSignifi"]
[804,"WP_LDLRAD4_AND_WHAT_WE_KNOW_ABOUT_IT",-0.751952375,-0.012555263,0.549528967,0.452172202,-0.253576492,-6.988342875,"NoSignifi"]
[803,"WP_TGFBETA_RECEPTOR_SIGNALING",-0.753681418,-0.006718297,0.548571742,0.451133291,-0.225181159,-6.987047115,"NoSignifi"]
[802,"REACTOME_MECP2_REGULATES_TRANSCRIPTION_OF_NEURONAL_LIGANDS",-0.754865048,-0.012525011,0.548076033,0.450422876,-0.310908537,-6.986158378,"NoSignifi"]
[801,"PID_ALK2_PATHWAY",-0.757624071,-0.011659977,0.546736264,0.448769375,-0.187024851,-6.984081333,"NoSignifi"]
[800,"REACTOME_PENTOSE_PHOSPHATE_PATHWAY",-0.761635484,-0.009396957,0.544485167,0.446371471,-0.21397894,-6.981047955,"NoSignifi"]
[799,"REACTOME_NR1H2_NR1H3_REGULATE_GENE_EXPRESSION_TO_CONTROL_BILE_ACID_HOMEOSTASIS",-0.764030692,-0.012045441,0.543189261,0.444943173,-0.265528404,-6.979229097,"NoSignifi"]
[798,"WP_HYPOTHETICAL_CRANIOFACIAL_DEVELOPMENT_PATHWAY",-0.766781866,-0.0129644,0.541604316,0.443305832,-0.221276846,-6.977132885,"NoSignifi"]
[797,"REACTOME_MAPK_FAMILY_SIGNALING_CASCADES",-0.766891699,-0.005585823,0.541604316,0.443240537,-0.135143087,-6.977049043,"NoSignifi"]
[796,"BIOCARTA_CDK5_PATHWAY",-0.768889005,-0.010284711,0.541443347,0.442054117,-0.270901025,-6.975522293,"NoSignifi"]
[795,"WP_G13_SIGNALING_PATHWAY",-0.779532816,-0.009721667,0.534840175,0.435762339,-0.150808847,-6.967319185,"NoSignifi"]
[794,"WP_FAS_LIGAND_PATHWAY_AND_STRESS_INDUCTION_OF_HEAT_SHOCK_PROTEINS",-0.779886647,-0.006772879,0.534805643,0.435554073,-0.143404312,-6.967044554,"NoSignifi"]
[793,"REACTOME_PYRUVATE_METABOLISM_AND_CITRIC_ACID_TCA_CYCLE",-0.780243334,-0.006441796,0.534769088,0.435344185,-0.238946183,-6.966767581,"NoSignifi"]
[792,"REACTOME_INSERTION_OF_TAIL_ANCHORED_PROTEINS_INTO_THE_ENDOPLASMIC_RETICULUM_MEMBRANE",-0.7810193,-0.010994161,0.534650855,0.434887779,-0.166658316,-6.966164593,"NoSignifi"]
[791,"PID_NFKAPPAB_CANONICAL_PATHWAY",-0.786500509,-0.008286178,0.530916893,0.431671734,-0.183276498,-6.961888196,"NoSignifi"]
[790,"BIOCARTA_ECM_PATHWAY",-0.787576273,-0.01148851,0.530582166,0.431042164,-0.251383469,-6.961045385,"NoSignifi"]
[789,"REACTOME_RHOC_GTPASE_CYCLE",-0.789043639,-0.006289581,0.529745796,0.430184276,-0.192373229,-6.959893915,"NoSignifi"]
[788,"PID_CMYB_PATHWAY",-0.790353398,-0.006648371,0.529023282,0.42941937,-0.191409853,-6.958864314,"NoSignifi"]
[787,"REACTOME_ERYTHROPOIETIN_ACTIVATES_PHOSPHOINOSITIDE_3_KINASE_PI3K",-0.790792971,-0.010791729,0.528926715,0.429162835,-0.181656435,-6.958518383,"NoSignifi"]
[786,"REACTOME_SIGNALING_BY_TGFB_FAMILY_MEMBERS",-0.790899959,-0.00635101,0.528926715,0.42910041,-0.202732536,-6.958434158,"NoSignifi"]
[785,"BIOCARTA_HSWI_SNF_PATHWAY",-0.791212421,-0.011809569,0.528926715,0.428918126,-0.300883643,-6.958188109,"NoSignifi"]
[784,"KEGG_DORSO_VENTRAL_AXIS_FORMATION",-0.791495006,-0.008196031,0.528926715,0.428753311,-0.254781377,-6.957965504,"NoSignifi"]
[783,"BIOCARTA_SALMONELLA_PATHWAY",-0.791953847,-0.017379264,0.528926715,0.428485775,-0.022937552,-6.957603884,"NoSignifi"]
[782,"PID_HIF1A_PATHWAY",-0.799198325,-0.010916878,0.52442606,0.424274637,-0.212262358,-6.951866642,"NoSignifi"]
[781,"REACTOME_CREB1_PHOSPHORYLATION_THROUGH_THE_ACTIVATION_OF_ADENYLATE_CYCLASE",-0.800963573,-0.012166853,0.523380165,0.423252198,-0.218690413,-6.950460749,"NoSignifi"]
[780,"REACTOME_RHO_GTPASE_EFFECTORS",-0.80521392,-0.006668202,0.520777092,0.42079631,-0.142513228,-6.947062935,"NoSignifi"]
[779,"REACTOME_NEPHRIN_FAMILY_INTERACTIONS",-0.805410921,-0.010894748,0.520777092,0.420682685,-0.245824625,-6.946905013,"NoSignifi"]
[778,"REACTOME_EXPORT_OF_VIRAL_RIBONUCLEOPROTEINS_FROM_NUCLEUS",-0.805484523,-0.006990609,0.520777092,0.420640237,-0.233812744,-6.946846001,"NoSignifi"]
[777,"WP_NSP1_FROM_SARSCOV2_INHIBITS_TRANSLATION_INITIATION_IN_THE_HOST_CELL",-0.81012838,-0.015367808,0.519223632,0.417967154,-0.149751968,-6.943111814,"NoSignifi"]
[776,"WP_PENTOSE_PHOSPHATE_PATHWAY_IN_SENESCENT_CELLS",-0.814698164,-0.012497584,0.516616585,0.41534651,-0.225738653,-6.939416249,"NoSignifi"]
[775,"REACTOME_INSULIN_PROCESSING",-0.817828683,-0.007951095,0.514821941,0.413556864,-0.160329031,-6.936872622,"NoSignifi"]
[774,"REACTOME_TRANSCRIPTIONAL_REGULATION_BY_MECP2",-0.819684182,-0.005885457,0.513906561,0.412498278,-0.196020561,-6.93536038,"NoSignifi"]
[773,"WP_LEUKOCYTEINTRINSIC_HIPPO_PATHWAY_FUNCTIONS",-0.81995706,-0.008356575,0.513906561,0.412342733,-0.179711572,-6.935137693,"NoSignifi"]
[772,"REACTOME_SYNTHESIS_OF_IP3_AND_IP4_IN_THE_CYTOSOL",-0.843615997,-0.007394228,0.499199244,0.398989493,-0.061097076,-6.915548886,"NoSignifi"]
[771,"PID_RAS_PATHWAY",-0.847382005,-0.007794744,0.496779576,0.39688823,-0.161824866,-6.912379392,"NoSignifi"]
[770,"REACTOME_ADP_SIGNALLING_THROUGH_P2Y_PURINOCEPTOR_12",-0.847746816,-0.010720112,0.496779576,0.396685037,-0.12773182,-6.912071615,"NoSignifi"]
[769,"REACTOME_PHASE_4_RESTING_MEMBRANE_POTENTIAL",-0.859524808,-0.005826355,0.489387949,0.390158732,0.244763538,-6.902063866,"NoSignifi"]
[768,"REACTOME_RHO_GTPASES_ACTIVATE_CIT",-0.867133284,-0.013573912,0.48537395,0.385977735,-0.186980992,-6.895525597,"NoSignifi"]
[767,"REACTOME_NUCLEAR_PORE_COMPLEX_NPC_DISASSEMBLY",-0.868197523,-0.006591451,0.484846641,0.385395107,-0.240885189,-6.894606464,"NoSignifi"]
[766,"WP_MAPK_PATHWAY_IN_CONGENITAL_THYROID_CANCER",-0.870170225,-0.011244801,0.483694724,0.384316556,-0.225860709,-6.892899755,"NoSignifi"]
[765,"REACTOME_METHYLATION",-0.874074529,-0.011060842,0.481218969,0.382187379,-0.136635937,-6.889510483,"NoSignifi"]
[764,"REACTOME_RHO_GTPASES_ACTIVATE_WASPS_AND_WAVES",-0.878121561,-0.011383442,0.479059212,0.379988024,-0.222384265,-6.88598131,"NoSignifi"]
[763,"BIOCARTA_ERBB4_PATHWAY",-0.884778546,-0.0105004,0.475731719,0.376387271,-0.003481596,-6.880140718,"NoSignifi"]
[762,"WP_TCA_CYCLE_IN_SENESCENCE",-0.885775191,-0.011819754,0.47549543,0.375850007,-0.258609908,-6.879262506,"NoSignifi"]
[761,"KEGG_FATTY_ACID_METABOLISM",-0.894826282,-0.007300885,0.470113876,0.370992526,-0.143136326,-6.871241744,"NoSignifi"]
[760,"WP_SELECTIVE_EXPRESSION_OF_CHEMOKINE_RECEPTORS_DURING_TCELL_POLARIZATION",-0.895272138,-0.008215015,0.470012552,0.370754259,0.088013159,-6.870844537,"NoSignifi"]
[759,"REACTOME_CARBOXYTERMINAL_POST_TRANSLATIONAL_MODIFICATIONS_OF_TUBULIN",-0.896419468,-0.007811276,0.469436262,0.370141559,-0.030728464,-6.869821486,"NoSignifi"]
[758,"SIG_PIP3_SIGNALING_IN_CARDIAC_MYOCTES",-0.897394669,-0.007397023,0.469089831,0.369621275,-0.220560226,-6.868950889,"NoSignifi"]
[757,"WP_SULINDAC_METABOLIC_PATHWAY",-0.898771229,-0.017391063,0.468446275,0.368887636,-0.217505039,-6.867720376,"NoSignifi"]
[756,"WP_PATHWAYS_AFFECTED_IN_ADENOID_CYSTIC_CARCINOMA",-0.90002775,-0.008303898,0.46799722,0.368218762,-0.188234719,-6.866595521,"NoSignifi"]
[755,"WP_HISTONE_MODIFICATIONS",-0.900043528,-0.008843552,0.46799722,0.368210368,-0.185407063,-6.866581386,"NoSignifi"]
[754,"BIOCARTA_IFNG_PATHWAY",-0.904274692,-0.015808326,0.465729101,0.365963621,-0.19238521,-6.862781976,"NoSignifi"]
[753,"REACTOME_SIGNAL_REGULATORY_PROTEIN_FAMILY_INTERACTIONS",-0.904475139,-0.010361447,0.465729101,0.365857397,-0.144080073,-6.862601541,"NoSignifi"]
[752,"REACTOME_SWITCHING_OF_ORIGINS_TO_A_POST_REPLICATIVE_STATE",-0.90527489,-0.011313142,0.465470298,0.36543377,-0.133981571,-6.861881239,"NoSignifi"]
[751,"REACTOME_RHOBTB3_ATPASE_CYCLE",-0.907764719,-0.011930669,0.464174755,0.364116876,-0.240111568,-6.859634678,"NoSignifi"]
[750,"REACTOME_PROCESSING_OF_INTRONLESS_PRE_MRNAS",-0.910268545,-0.010311257,0.462729766,0.362795576,-0.252603464,-6.857369271,"NoSignifi"]
[749,"KEGG_NON_HOMOLOGOUS_END_JOINING",-0.916828601,-0.011425637,0.459674401,0.359348025,-0.070175837,-6.85140431,"NoSignifi"]
[748,"PID_AURORA_B_PATHWAY",-0.919290084,-0.008962737,0.458421484,0.358059758,-0.102374426,-6.849155079,"NoSignifi"]
[747,"REACTOME_RAP1_SIGNALLING",-0.92596236,-0.012326642,0.455343838,0.354582335,-0.172930031,-6.843027846,"NoSignifi"]
[746,"WP_EBOLA_VIRUS_INFECTION_IN_HOST",-0.93342428,-0.007592498,0.451358452,0.350718743,-0.141453857,-6.836123034,"NoSignifi"]
[745,"BIOCARTA_PYK2_PATHWAY",-0.93798301,-0.01038829,0.44911642,0.348371544,-0.23873981,-6.831877412,"NoSignifi"]
[744,"REACTOME_MRNA_EDITING",-0.938786975,-0.014246418,0.448865888,0.347958637,-0.028241852,-6.831126522,"NoSignifi"]
[743,"REACTOME_TRAFFICKING_OF_GLUR2_CONTAINING_AMPA_RECEPTORS",-0.943202967,-0.010994595,0.446637075,0.345696194,-0.11712405,-6.8269906,"NoSignifi"]
[742,"PID_MAPK_TRK_PATHWAY",-0.944703712,-0.009315513,0.44584047,0.344929458,-0.244805549,-6.82558062,"NoSignifi"]
[741,"REACTOME_HATS_ACETYLATE_HISTONES",-0.950058643,-0.006606259,0.443280588,0.342202462,-0.262387484,-6.820531303,"NoSignifi"]
[740,"BIOCARTA_RAN_PATHWAY",-0.952525004,-0.021342232,0.442045364,0.340951122,-0.183736588,-6.81819611,"NoSignifi"]
[739,"REACTOME_RESPONSE_OF_MTB_TO_PHAGOCYTOSIS",-0.95437978,-0.013289181,0.44111268,0.340012013,-0.155463336,-6.816435991,"NoSignifi"]
[738,"PID_SYNDECAN_4_PATHWAY",-0.955471716,-0.011962875,0.440689334,0.339459922,-0.194366618,-6.815398183,"NoSignifi"]
[737,"REACTOME_RHO_GTPASES_ACTIVATE_RHOTEKIN_AND_RHOPHILINS",-0.962163108,-0.015972238,0.43669543,0.336089275,-0.097403895,-6.809012586,"NoSignifi"]
[736,"REACTOME_CHROMATIN_MODIFYING_ENZYMES",-0.963663451,-0.006596919,0.435908057,0.335336478,-0.240815272,-6.807574699,"NoSignifi"]
[735,"PID_INTEGRIN4_PATHWAY",-0.966591078,-0.016214287,0.434573444,0.333870672,-0.152320446,-6.804762495,"NoSignifi"]
[734,"PID_IL2_PI3K_PATHWAY",-0.966830422,-0.010251344,0.434573444,0.333751021,-0.204129058,-6.804532211,"NoSignifi"]
[733,"REACTOME_CYTOSOLIC_TRNA_AMINOACYLATION",-0.969877869,-0.017218458,0.433197541,0.332229977,-0.222797879,-6.801595135,"NoSignifi"]
[732,"KEGG_ALLOGRAFT_REJECTION",-0.971021501,-0.010240524,0.432834947,0.331660325,0.039864481,-6.800490539,"NoSignifi"]
[731,"PID_FOXO_PATHWAY",-0.97263351,-0.010538425,0.432049965,0.330858444,-0.206144108,-6.798931346,"NoSignifi"]
[730,"REACTOME_ADRENALINE_NORADRENALINE_INHIBITS_INSULIN_SECRETION",-0.973960874,-0.010080052,0.431686979,0.330199101,-0.081295955,-6.797645531,"NoSignifi"]
[729,"REACTOME_FCGAMMA_RECEPTOR_FCGR_DEPENDENT_PHAGOCYTOSIS",-0.977183167,-0.009402942,0.429977712,0.328602031,-0.157689993,-6.794516816,"NoSignifi"]
[728,"PID_ARF6_DOWNSTREAM_PATHWAY",-0.977584012,-0.015560398,0.429907679,0.328403711,-0.205365409,-6.79412689,"NoSignifi"]
[727,"WP_OMEGA9_FATTY_ACID_SYNTHESIS",-0.977709248,-0.010118127,0.429907679,0.328341766,-0.126235419,-6.794005033,"NoSignifi"]
[726,"REACTOME_CHL1_INTERACTIONS",-0.984507357,-0.015798522,0.426379639,0.32499061,-0.057352224,-6.787366926,"NoSignifi"]
[725,"REACTOME_INTEGRATION_OF_ENERGY_METABOLISM",-0.986145617,-0.00678497,0.42551252,0.324186366,-0.128757843,-6.785760352,"NoSignifi"]
[724,"BIOCARTA_ERBB3_PATHWAY",-0.987723201,-0.018396348,0.424873274,0.323413135,-0.12789256,-6.784210761,"NoSignifi"]
[723,"KEGG_THYROID_CANCER",-0.989327883,-0.009987674,0.424029265,0.322627858,-0.220424389,-6.782632013,"NoSignifi"]
[722,"WP_EICOSANOID_METABOLISM_VIA_CYTOCHROME_P450_MONOOXYGENASES_PATHWAY",-0.992818504,-0.013042003,0.422163607,0.320923968,-0.025318853,-6.779188965,"NoSignifi"]
[721,"REACTOME_CELL_CYCLE_CHECKPOINTS",-0.995145504,-0.007470015,0.421184722,0.319791355,-0.12739476,-6.776886949,"NoSignifi"]
[720,"REACTOME_ANTIGEN_PRESENTATION_FOLDING_ASSEMBLY_AND_PEPTIDE_LOADING_OF_CLASS_I_MHC",-0.99851697,-0.01457984,0.419264205,0.31815502,-0.203480657,-6.77354213,"NoSignifi"]
[719,"REACTOME_TELOMERE_EXTENSION_BY_TELOMERASE",-0.999621078,-0.009387152,0.418931491,0.317620339,-0.189466023,-6.772444293,"NoSignifi"]
[718,"WP_EUKARYOTIC_TRANSCRIPTION_INITIATION",-1.002832257,-0.009613442,0.417255561,0.316068628,-0.224333374,-6.769244462,"NoSignifi"]
[717,"WP_HEPATOCYTE_GROWTH_FACTOR_RECEPTOR_SIGNALING",-1.011482265,-0.011014871,0.412320307,0.311913577,-0.230468486,-6.76057402,"NoSignifi"]
[716,"REACTOME_BETA_OXIDATION_OF_HEXANOYL_COA_TO_BUTANOYL_COA",-1.012624121,-0.018293905,0.41196567,0.311367788,-0.229972019,-6.759423909,"NoSignifi"]
[715,"WP_ENDODERM_DIFFERENTIATION",-1.020329388,-0.005936851,0.408206035,0.307701282,-0.169867725,-6.75162905,"NoSignifi"]
[714,"WP_HEART_DEVELOPMENT",-1.021958907,-0.008649933,0.407546455,0.306929564,-0.127633781,-6.749973023,"NoSignifi"]
[713,"PID_ALK1_PATHWAY",-1.022298631,-0.011771387,0.407515291,0.306768837,-0.255244751,-6.74962744,"NoSignifi"]
[712,"BIOCARTA_RNA_PATHWAY",-1.02302922,-0.015972462,0.407238588,0.306423376,-0.229330562,-6.748883863,"NoSignifi"]
[711,"BIOCARTA_CTCF_PATHWAY",-1.023464911,-0.010819512,0.407147203,0.306217482,-0.290684481,-6.748440174,"NoSignifi"]
[710,"WP_NRF2_PATHWAY",-1.026827403,-0.005653792,0.405401655,0.304631557,-0.041954253,-6.745009605,"NoSignifi"]
[709,"REACTOME_G_BETA_GAMMA_SIGNALLING_THROUGH_PI3KGAMMA",-1.034719561,-0.011577625,0.40101579,0.300930677,-0.095982144,-6.736913513,"NoSignifi"]
[708,"REACTOME_VEGF_LIGAND_RECEPTOR_INTERACTIONS",-1.037056316,-0.014381575,0.399922266,0.299840675,-0.021268491,-6.734504495,"NoSignifi"]
[707,"REACTOME_PHYSIOLOGICAL_FACTORS",-1.03769247,-0.015264672,0.399886376,0.299544392,-0.133379769,-6.733847729,"NoSignifi"]
[706,"BIOCARTA_IL17_PATHWAY",-1.041324032,-0.009136498,0.397812299,0.297856767,0.323033964,-6.730090794,"NoSignifi"]
[705,"REACTOME_CHAPERONE_MEDIATED_AUTOPHAGY",-1.043027872,-0.01947634,0.396936286,0.29706717,-0.154056124,-6.728323613,"NoSignifi"]
[704,"BIOCARTA_VIP_PATHWAY",-1.044522646,-0.012126046,0.396369007,0.296375613,-0.173028272,-6.726770894,"NoSignifi"]
[703,"WP_MITOCHONDRIAL_GENE_EXPRESSION",-1.045136784,-0.009856267,0.396167886,0.296091795,-0.157180647,-6.726132305,"NoSignifi"]
[702,"KEGG_JAK_STAT_SIGNALING_PATHWAY",-1.046193479,-0.005200913,0.395871863,0.29560388,-0.104662497,-6.725032663,"NoSignifi"]
[701,"PID_CXCR4_PATHWAY",-1.052673069,-0.007695969,0.39258927,0.292623797,-0.138466967,-6.718265449,"NoSignifi"]
[700,"REACTOME_PASSIVE_TRANSPORT_BY_AQUAPORINS",-1.055456049,-0.010655237,0.391411026,0.291350073,0.280295599,-6.715346122,"NoSignifi"]
[699,"REACTOME_RND3_GTPASE_CYCLE",-1.056167551,-0.011673805,0.391151341,0.29102503,-0.182001301,-6.714598525,"NoSignifi"]
[698,"SA_TRKA_RECEPTOR",-1.063916942,-0.012309022,0.387642723,0.287500598,-0.269496501,-6.706423422,"NoSignifi"]
[697,"REACTOME_NRCAM_INTERACTIONS",-1.06552942,-0.012914984,0.387010337,0.28677088,-0.048647895,-6.704714861,"NoSignifi"]
[696,"WP_ERBB_SIGNALING_PATHWAY",-1.071118197,-0.006859919,0.384308927,0.284251399,-0.222005379,-6.698773059,"NoSignifi"]
[695,"REACTOME_SERINE_BIOSYNTHESIS",-1.073791484,-0.019037402,0.383035602,0.28305157,-0.148894513,-6.695919932,"NoSignifi"]
[694,"PID_THROMBIN_PAR4_PATHWAY",-1.074073109,-0.018073024,0.383035602,0.282925371,-0.143017001,-6.695618949,"NoSignifi"]
[693,"WP_HOSTPATHOGEN_INTERACTION_OF_HUMAN_CORONAVIRUSES_AUTOPHAGY",-1.077223289,-0.011718948,0.38165389,0.281516342,-0.247196791,-6.692246848,"NoSignifi"]
[692,"REACTOME_PLASMA_LIPOPROTEIN_ASSEMBLY_REMODELING_AND_CLEARANCE",-1.079608353,-0.008074124,0.380559463,0.280452713,-0.097372982,-6.689687202,"NoSignifi"]
[691,"PID_NOTCH_PATHWAY",-1.080479663,-0.008653044,0.380554912,0.280064831,-0.191747954,-6.688750704,"NoSignifi"]
[690,"WP_ALPHA_6_BETA_4_SIGNALING_PATHWAY",-1.081616519,-0.011455984,0.380215994,0.279559284,-0.243207987,-6.687527658,"NoSignifi"]
[689,"WP_METABOLISM_OF_SPINGOLIPIDS_IN_ER_AND_GOLGI_APPARATUS",-1.084744763,-0.009270151,0.378767099,0.278171396,-0.129193564,-6.684155619,"NoSignifi"]
[688,"KEGG_LONG_TERM_POTENTIATION",-1.086710135,-0.008631093,0.378022916,0.277301837,-0.150058177,-6.682032103,"NoSignifi"]
[687,"REACTOME_WNT5A_DEPENDENT_INTERNALIZATION_OF_FZD2_FZD5_AND_ROR2",-1.091570681,-0.015726124,0.375953967,0.275159303,-0.197567877,-6.676763965,"NoSignifi"]
[686,"REACTOME_DEFENSINS",-1.094975028,-0.009972108,0.374084997,0.273665414,0.191997038,-6.673060156,"NoSignifi"]
[685,"KEGG_SPLICEOSOME",-1.109276872,-0.010923465,0.367790456,0.267450183,-0.205872849,-6.657374417,"NoSignifi"]
[684,"REACTOME_NUCLEOTIDE_SALVAGE",-1.11561441,-0.010858232,0.364891116,0.264727337,-0.135505966,-6.650358638,"NoSignifi"]
[683,"KEGG_VIRAL_MYOCARDITIS",-1.126149949,-0.009909325,0.359545077,0.260243304,-0.152769724,-6.638607255,"NoSignifi"]
[682,"WP_ASPIRIN_AND_MIRNAS",-1.126157155,-0.013275445,0.359545077,0.260240255,-0.109156336,-6.63859918,"NoSignifi"]
[681,"KEGG_AMINO_SUGAR_AND_NUCLEOTIDE_SUGAR_METABOLISM",-1.130771244,-0.010067124,0.35751622,0.258293126,-0.275012011,-6.633417841,"NoSignifi"]
[680,"REACTOME_DNA_REPLICATION",-1.13224488,-0.011787406,0.356824767,0.257673392,-0.133078954,-6.63175858,"NoSignifi"]
[679,"WP_ANDROGEN_RECEPTOR_SIGNALING_PATHWAY",-1.135654011,-0.010564325,0.355010449,0.256243649,-0.19328602,-6.62791175,"NoSignifi"]
[678,"WP_AIRWAY_SMOOTH_MUSCLE_CELL_CONTRACTION",-1.142124214,-0.016923652,0.351600213,0.25354532,-0.150047508,-6.620579078,"NoSignifi"]
[677,"PID_FOXM1_PATHWAY",-1.142812385,-0.008496998,0.351367963,0.253259495,-0.136344114,-6.619796726,"NoSignifi"]
[676,"WP_EBSTEINBARR_VIRUS_LMP1_SIGNALING",-1.154083241,-0.011710382,0.345887382,0.248610196,-0.180247401,-6.606916422,"NoSignifi"]
[675,"REACTOME_EXTRA_NUCLEAR_ESTROGEN_SIGNALING",-1.159187219,-0.009822814,0.343307402,0.246524547,-0.165802669,-6.601042085,"NoSignifi"]
[674,"REACTOME_RAS_ACTIVATION_UPON_CA2_INFLUX_THROUGH_NMDA_RECEPTOR",-1.164533611,-0.01040915,0.340443053,0.24435303,-0.07454888,-6.594860986,"NoSignifi"]
[673,"BIOCARTA_BIOPEPTIDES_PATHWAY",-1.1670815939999999,-0.012786709,0.339485717,0.243322872,-0.230035661,-6.591905206,"NoSignifi"]
[672,"KEGG_GLYCOSAMINOGLYCAN_BIOSYNTHESIS_KERATAN_SULFATE",-1.167840728,-0.012810901,0.339344416,0.243016543,-0.196945426,-6.591023327,"NoSignifi"]
[671,"PID_PI3K_PLC_TRK_PATHWAY",-1.178301206,-0.012372457,0.334462938,0.238823092,-0.200682922,-6.578813184,"NoSignifi"]
[670,"REACTOME_CELLULAR_SENESCENCE",-1.184542762,-0.008036988,0.331307628,0.236345421,-0.207785933,-6.571475848,"NoSignifi"]
[669,"WP_TGFBETA_SIGNALING_PATHWAY",-1.187355376,-0.009889744,0.330062554,0.235234882,-0.220954817,-6.568156796,"NoSignifi"]
[668,"REACTOME_CARGO_RECOGNITION_FOR_CLATHRIN_MEDIATED_ENDOCYTOSIS",-1.188622685,-0.008399807,0.329635495,0.234735705,-0.168423802,-6.566658726,"NoSignifi"]
[667,"WP_PHYSICOCHEMICAL_FEATURES_AND_TOXICITYASSOCIATED_PATHWAYS",-1.194294939,-0.009784482,0.326858046,0.232510675,-0.168313143,-6.559934076,"NoSignifi"]
[666,"REACTOME_ACTIVATION_OF_AMPK_DOWNSTREAM_OF_NMDARS",-1.198113889,-0.014767189,0.325502033,0.231021094,-0.106890295,-6.555388574,"NoSignifi"]
[665,"REACTOME_HDR_THROUGH_MMEJ_ALT_NHEJ",-1.200290482,-0.013682349,0.32465085,0.230175156,-0.199634143,-6.552791403,"NoSignifi"]
[664,"REACTOME_ENDOSOMAL_VACUOLAR_PATHWAY",-1.20108903,-0.025939152,0.324461351,0.229865352,-0.233351077,-6.551837374,"NoSignifi"]
[663,"PID_AVB3_OPN_PATHWAY",-1.201333262,-0.01465949,0.324461351,0.22977066,-0.164853827,-6.551545462,"NoSignifi"]
[662,"REACTOME_ONCOGENE_INDUCED_SENESCENCE",-1.20371149,-0.012218792,0.323550356,0.228850033,-0.243045472,-6.54869985,"NoSignifi"]
[661,"WP_BONE_MORPHOGENIC_PROTEIN_BMP_SIGNALING_AND_REGULATION",-1.20461893,-0.016248609,0.323208609,0.228499451,-0.256887194,-6.547612594,"NoSignifi"]
[660,"REACTOME_RAF_ACTIVATION",-1.207449586,-0.012282439,0.321818529,0.22740831,-0.215088,-6.544215763,"NoSignifi"]
[659,"KEGG_MTOR_SIGNALING_PATHWAY",-1.207519784,-0.010861978,0.321818529,0.227381298,-0.223773963,-6.544131423,"NoSignifi"]
[658,"REACTOME_POST_CHAPERONIN_TUBULIN_FOLDING_PATHWAY",-1.211641309,-0.017612846,0.320458066,0.225799351,-0.100033832,-6.539171011,"NoSignifi"]
[657,"REACTOME_SUMOYLATION_OF_IMMUNE_RESPONSE_PROTEINS",-1.220827457,-0.018568741,0.316250144,0.222301802,-0.167328219,-6.528054407,"NoSignifi"]
[656,"REACTOME_INTERACTIONS_OF_REV_WITH_HOST_CELLULAR_PROTEINS",-1.221014874,-0.010776293,0.316250144,0.22223085,-0.207615631,-6.527826731,"NoSignifi"]
[655,"REACTOME_PLATELET_SENSITIZATION_BY_LDL",-1.221351225,-0.013108539,0.316250144,0.222103558,-0.202697687,-6.527418043,"NoSignifi"]
[654,"REACTOME_PKMTS_METHYLATE_HISTONE_LYSINES",-1.224364126,-0.010921691,0.315104232,0.220965649,-0.20114877,-6.523752161,"NoSignifi"]
[653,"REACTOME_TP53_REGULATES_TRANSCRIPTION_OF_GENES_INVOLVED_IN_G2_CELL_CYCLE_ARREST",-1.225726667,-0.014763929,0.314523421,0.220452421,-0.284643109,-6.522091357,"NoSignifi"]
[652,"PID_LKB1_PATHWAY",-1.22868019,-0.011678964,0.313241438,0.219342859,-0.201499305,-6.51848497,"NoSignifi"]
[651,"REACTOME_SLBP_DEPENDENT_PROCESSING_OF_REPLICATION_DEPENDENT_HISTONE_PRE_MRNAS",-1.242727025,-0.024166201,0.307113274,0.21412074,-0.153929783,-6.501214533,"NoSignifi"]
[650,"BIOCARTA_MCALPAIN_PATHWAY",-1.244092482,-0.014635766,0.306540192,0.213617938,-0.186752497,-6.499525265,"NoSignifi"]
[649,"WP_DIFFERENTIATION_OF_WHITE_AND_BROWN_ADIPOCYTE",-1.248866156,-0.010712691,0.30417438,0.21186683,-0.038137504,-6.493604984,"NoSignifi"]
[648,"WP_FOLATEALCOHOL_AND_CANCER_PATHWAY_HYPOTHESES",-1.253081089,-0.018140653,0.302259337,0.210329333,-0.118196941,-6.488358835,"NoSignifi"]
[647,"WP_RETINOBLASTOMA_GENE_IN_CANCER",-1.259792305,-0.007474713,0.29890995,0.207897961,-0.171659714,-6.479969247,"NoSignifi"]
[646,"PID_P38_GAMMA_DELTA_PATHWAY",-1.261084547,-0.016047517,0.298529356,0.207432153,-0.204113253,-6.478348698,"NoSignifi"]
[645,"REACTOME_MATURATION_OF_SARS_COV_2_SPIKE_PROTEIN",-1.262603818,-0.011938295,0.297886995,0.206885478,-0.207638404,-6.47644132,"NoSignifi"]
[644,"WP_CANONICAL_NFKB_PATHWAY",-1.273470887,-0.018298276,0.293011154,0.203005707,-0.235506113,-6.462731349,"NoSignifi"]
[643,"WP_FAMILIAL_PARTIAL_LIPODYSTROPHY_FPLD",-1.276962985,-0.010542421,0.291653348,0.201770285,-0.212580007,-6.45830079,"NoSignifi"]
[642,"REACTOME_SENESCENCE_ASSOCIATED_SECRETORY_PHENOTYPE_SASP",-1.280663333,-0.012516735,0.29005218,0.200467186,-0.190801494,-6.453592801,"NoSignifi"]
[641,"WP_MELANOMA",-1.281641558,-0.010385519,0.28983773,0.200123728,-0.218457513,-6.452345923,"NoSignifi"]
[640,"REACTOME_TRANSCRIPTIONAL_REGULATION_OF_TESTIS_DIFFERENTIATION",-1.282114796,-0.023400546,0.289738648,0.199957726,0.018180619,-6.451742376,"NoSignifi"]
[639,"REACTOME_RHO_GTPASES_ACTIVATE_PAKS",-1.28215478,-0.019765751,0.289738648,0.199943706,-0.198792681,-6.451691372,"NoSignifi"]
[638,"REACTOME_GAP_JUNCTION_TRAFFICKING_AND_REGULATION",-1.292509953,-0.014824424,0.285327281,0.196336691,-0.107810991,-6.438428765,"NoSignifi"]
[637,"REACTOME_HSF1_DEPENDENT_TRANSACTIVATION",-1.294261549,-0.015278224,0.284726234,0.195731305,-0.174414825,-6.436174841,"NoSignifi"]
[636,"REACTOME_NADE_MODULATES_DEATH_SIGNALLING",-1.295294079,-0.024521142,0.284347366,0.195375085,-0.047983309,-6.434844771,"NoSignifi"]
[635,"REACTOME_METABOLISM_OF_PORPHYRINS",-1.295587488,-0.012976349,0.284339552,0.195273946,-0.143631515,-6.434466619,"NoSignifi"]
[634,"WP_LEPTININSULIN_SIGNALING_OVERLAP",-1.299240279,-0.014299886,0.282788196,0.194018038,-0.234143329,-6.429751655,"NoSignifi"]
[633,"KEGG_SYSTEMIC_LUPUS_ERYTHEMATOSUS",-1.302547488,-0.011059512,0.282059526,0.192886076,0.081998134,-6.425471334,"NoSignifi"]
[632,"REACTOME_SMAD2_SMAD3_SMAD4_HETEROTRIMER_REGULATES_TRANSCRIPTION",-1.303746643,-0.013918155,0.281786856,0.192476842,-0.271526971,-6.423916657,"NoSignifi"]
[631,"KEGG_TIGHT_JUNCTION",-1.304044002,-0.010001382,0.281777378,0.192375462,-0.123397473,-6.423530916,"NoSignifi"]
[630,"REACTOME_INSULIN_RECEPTOR_RECYCLING",-1.3041316,-0.015139792,0.281777378,0.192345604,-0.166164174,-6.423417267,"NoSignifi"]
[629,"REACTOME_SYNTHESIS_SECRETION_AND_INACTIVATION_OF_GLUCAGON_LIKE_PEPTIDE_1_GLP_1",-1.304309369,-0.020721983,0.281777378,0.192285022,-0.080359009,-6.423186603,"NoSignifi"]
[628,"REACTOME_RHO_GTPASES_ACTIVATE_FORMINS",-1.304876891,-0.009755186,0.281777378,0.192091709,-0.111131554,-6.422450008,"NoSignifi"]
[627,"KEGG_LYSINE_DEGRADATION",-1.305877753,-0.010532199,0.281557432,0.191751138,-0.192521688,-6.421150197,"NoSignifi"]
[626,"BIOCARTA_SET_PATHWAY",-1.310716593,-0.022742973,0.27956371,0.190110855,-0.182536884,-6.414852002,"NoSignifi"]
[625,"REACTOME_MITOCHONDRIAL_IRON_SULFUR_CLUSTER_BIOGENESIS",-1.312144719,-0.016475197,0.279131231,0.189628728,-0.247420125,-6.41298872,"NoSignifi"]
[624,"WP_SEROTONIN_RECEPTOR_2_AND_ELKSRFGATA4_SIGNALING",-1.315859699,-0.014656542,0.27798044,0.188378796,-0.232347976,-6.408132285,"NoSignifi"]
[623,"REACTOME_RNA_POLYMERASE_II_TRANSCRIBES_SNRNA_GENES",-1.317267913,-0.009163563,0.277559528,0.187906585,-0.254902103,-6.406287803,"NoSignifi"]
[622,"REACTOME_HDMS_DEMETHYLATE_HISTONES",-1.322394534,-0.015578929,0.275305081,0.186194881,-0.235728427,-6.399556314,"NoSignifi"]
[621,"BIOCARTA_SM_PATHWAY",-1.32268131,-0.026266198,0.275301113,0.186099472,-0.156352213,-6.399178993,"NoSignifi"]
[620,"WP_PDGF_PATHWAY",-1.333597439,-0.015087475,0.270372461,0.182494581,-0.180518731,-6.384755553,"NoSignifi"]
[619,"SIG_REGULATION_OF_THE_ACTIN_CYTOSKELETON_BY_RHO_GTPASES",-1.342180061,-0.017972899,0.266626708,0.179696882,-0.172314502,-6.373332279,"NoSignifi"]
[618,"REACTOME_SEMAPHORIN_INTERACTIONS",-1.350216709,-0.014623715,0.26304567,0.177106196,-0.135887883,-6.362569372,"NoSignifi"]
[617,"WP_MODULATORS_OF_TCR_SIGNALING_AND_T_CELL_ACTIVATION",-1.36163059,-0.008609169,0.258557612,0.173474828,-0.110781813,-6.347173365,"NoSignifi"]
[616,"REACTOME_RUNX2_REGULATES_CHONDROCYTE_MATURATION",-1.362959571,-0.023352264,0.258062398,0.173055653,-0.273848675,-6.345372316,"NoSignifi"]
[615,"REACTOME_RSK_ACTIVATION",-1.370973338,-0.022017082,0.255214398,0.170544077,-0.269663094,-6.334474806,"NoSignifi"]
[614,"REACTOME_DOPAMINE_CLEARANCE_FROM_THE_SYNAPTIC_CLEFT",-1.373145325,-0.046542499,0.254369884,0.169868091,-0.1080037,-6.33151025,"NoSignifi"]
[613,"REACTOME_RHO_GTPASES_ACTIVATE_KTN1",-1.377560755,-0.025874757,0.252702948,0.168500078,-0.121968989,-6.32546917,"NoSignifi"]
[612,"WP_SERINE_METABOLISM",-1.380880623,-0.018923279,0.251639219,0.167476961,-0.152533707,-6.320914262,"NoSignifi"]
[611,"WP_ATR_SIGNALING",-1.381756351,-0.013919557,0.251362092,0.167207859,-0.110018386,-6.319710926,"NoSignifi"]
[610,"REACTOME_ACTIVATION_OF_BAD_AND_TRANSLOCATION_TO_MITOCHONDRIA",-1.386253106,-0.021589497,0.249582584,0.165831173,-0.200232499,-6.313519954,"NoSignifi"]
[609,"BIOCARTA_P53HYPOXIA_PATHWAY",-1.390291232,-0.016312454,0.247947178,0.164602185,-0.249674188,-6.307943299,"NoSignifi"]
[608,"WP_EXERCISEINDUCED_CIRCADIAN_REGULATION",-1.396406547,-0.015731349,0.245537053,0.162754099,-0.175464359,-6.299467223,"NoSignifi"]
[607,"REACTOME_PYRIMIDINE_CATABOLISM",-1.398176468,-0.018303021,0.244858958,0.162222152,-0.114300466,-6.297007114,"NoSignifi"]
[606,"REACTOME_E2F_MEDIATED_REGULATION_OF_DNA_REPLICATION",-1.403413996,-0.014434879,0.24279194,0.160655712,-0.127147565,-6.28970897,"NoSignifi"]
[605,"WP_FBXL10_ENHANCEMENT_OF_MAPERK_SIGNALING_IN_DIFFUSE_LARGE_BCELL_LYMPHOMA",-1.403752202,-0.019097301,0.24279194,0.160554957,-0.262269866,-6.289236768,"NoSignifi"]
[604,"REACTOME_INCRETIN_SYNTHESIS_SECRETION_AND_INACTIVATION",-1.404478529,-0.021860134,0.242632878,0.160338736,-0.081124505,-6.288222285,"NoSignifi"]
[603,"REACTOME_NEGATIVE_FEEDBACK_REGULATION_OF_MAPK_PATHWAY",-1.411136574,-0.023315901,0.240384188,0.158366949,-0.337394918,-6.278898401,"NoSignifi"]
[602,"PID_ARF_3PATHWAY",-1.418616026,-0.019270664,0.237906744,0.156173878,-0.216685293,-6.268371741,"NoSignifi"]
[601,"PID_RAC1_PATHWAY",-1.421997946,-0.014506371,0.236529102,0.155189859,-0.134069627,-6.263593761,"NoSignifi"]
[600,"REACTOME_ACETYLCHOLINE_REGULATES_INSULIN_SECRETION",-1.440009506,-0.02413512,0.229960823,0.150028331,-0.138113466,-6.237955773,"NoSignifi"]
[599,"REACTOME_TRANSCRIPTION_OF_E2F_TARGETS_UNDER_NEGATIVE_CONTROL_BY_DREAM_COMPLEX",-1.443963299,-0.015292499,0.228487246,0.148913042,-0.184582192,-6.232284771,"NoSignifi"]
[598,"KEGG_OOCYTE_MEIOSIS",-1.447454762,-0.01091164,0.227344432,0.147933444,-0.152745156,-6.227263998,"NoSignifi"]
[597,"REACTOME_AGGREPHAGY",-1.447522405,-0.021295161,0.227344432,0.147914515,-0.146660283,-6.227166607,"NoSignifi"]
[596,"KEGG_REGULATION_OF_AUTOPHAGY",-1.448163522,-0.015012685,0.227344432,0.147735191,-0.231391077,-6.226243313,"NoSignifi"]
[595,"PID_ECADHERIN_STABILIZATION_PATHWAY",-1.449866074,-0.014828858,0.226770905,0.147259786,-0.216427007,-6.223789434,"NoSignifi"]
[594,"PID_LIS1_PATHWAY",-1.455669494,-0.019284249,0.22487216,0.145648085,-0.117314961,-6.215403377,"NoSignifi"]
[593,"BIOCARTA_SAM68_PATHWAY",-1.455934875,-0.025803962,0.22487216,0.145574709,-0.292821229,-6.215019097,"NoSignifi"]
[592,"WP_TCA_CYCLE_NUTRIENT_USE_AND_INVASIVENESS_OF_OVARIAN_CANCER",-1.456359771,-0.030092565,0.22487216,0.145457287,-0.23158442,-6.21440369,"NoSignifi"]
[591,"WP_STATIN_INHIBITION_OF_CHOLESTEROL_PRODUCTION",-1.461933156,-0.013100862,0.222905412,0.143923771,0.0297559,-6.206314756,"NoSignifi"]
[590,"REACTOME_SUMOYLATION_OF_DNA_REPLICATION_PROTEINS",-1.465832816,-0.011307503,0.221370527,0.142858178,-0.167851956,-6.200636653,"NoSignifi"]
[589,"REACTOME_GAP_JUNCTION_DEGRADATION",-1.475425007,-0.026293042,0.218031664,0.140262876,-0.158988983,-6.186605718,"NoSignifi"]
[588,"WP_CELLTYPE_DEPENDENT_SELECTIVITY_OF_CCK2R_SIGNALING",-1.482083452,-0.017193866,0.215942962,0.138482788,0.01795804,-6.176812419,"NoSignifi"]
[587,"REACTOME_SUMOYLATION_OF_RNA_BINDING_PROTEINS",-1.486406613,-0.012209844,0.214380503,0.137336382,-0.199218339,-6.170430319,"NoSignifi"]
[586,"REACTOME_RHO_GTPASES_ACTIVATE_ROCKS",-1.48917531,-0.024749743,0.213391235,0.136606041,-0.195742911,-6.166333268,"NoSignifi"]
[585,"REACTOME_CASPASE_ACTIVATION_VIA_DEPENDENCE_RECEPTORS_IN_THE_ABSENCE_OF_LIGAND",-1.495014255,-0.020687976,0.21140728,0.135075652,-0.084191782,-6.157668001,"NoSignifi"]
[584,"REACTOME_ENOS_ACTIVATION",-1.502000547,-0.02108699,0.209230508,0.133262004,-0.140004363,-6.147255563,"NoSignifi"]
[583,"REACTOME_NUCLEAR_EVENTS_KINASE_AND_TRANSCRIPTION_FACTOR_ACTIVATION",-1.505637015,-0.013204199,0.208075726,0.132325468,-0.182281783,-6.14181657,"NoSignifi"]
[582,"REACTOME_PI5P_REGULATES_TP53_ACETYLATION",-1.508935914,-0.021230628,0.206980372,0.13148029,-0.311667226,-6.136871122,"NoSignifi"]
[581,"REACTOME_TRANSCRIPTIONAL_REGULATION_OF_GRANULOPOIESIS",-1.513865043,-0.014250131,0.205113418,0.130225259,-0.110689009,-6.129461642,"NoSignifi"]
[580,"KEGG_GRAFT_VERSUS_HOST_DISEASE",-1.522833712,-0.016392313,0.202305554,0.127965588,-0.001885712,-6.115918081,"NoSignifi"]
[579,"BIOCARTA_DICER_PATHWAY",-1.525367763,-0.026588131,0.201519594,0.12733269,-0.284140558,-6.112076958,"NoSignifi"]
[578,"REACTOME_RHO_GTPASES_ACTIVATE_PKNS",-1.529103038,-0.021110882,0.200263685,0.126404225,-0.205963203,-6.106403399,"NoSignifi"]
[577,"BIOCARTA_CELL2CELL_PATHWAY",-1.531681511,-0.02578727,0.199466027,0.125766387,-0.168267568,-6.102478846,"NoSignifi"]
[576,"REACTOME_RHO_GTPASES_ACTIVATE_NADPH_OXIDASES",-1.53307224,-0.015315607,0.199150819,0.125423405,-0.109482909,-6.100359356,"NoSignifi"]
[575,"REACTOME_REGULATION_OF_MECP2_EXPRESSION_AND_ACTIVITY",-1.535168654,-0.014632295,0.198528456,0.124907765,-0.268855801,-6.097160764,"NoSignifi"]
[574,"BIOCARTA_RANMS_PATHWAY",-1.540135697,-0.023925264,0.197019052,0.123692662,-0.140765553,-6.089564926,"NoSignifi"]
[573,"WP_CHEMOKINE_SIGNALING_PATHWAY",-1.550052937,-0.007710615,0.193927049,0.121294217,-0.097496376,-6.07432579,"NoSignifi"]
[572,"WP_MESODERMAL_COMMITMENT_PATHWAY",-1.55615874,-0.009212501,0.192112507,0.119835757,-0.173829388,-6.064894899,"NoSignifi"]
[571,"REACTOME_NETRIN_1_SIGNALING",-1.592378469,-0.010793642,0.180742372,0.111464898,-0.111582338,-6.008190372,"NoSignifi"]
[570,"REACTOME_SUPPRESSION_OF_APOPTOSIS",-1.5930933,-0.026794757,0.180580845,0.111304462,-0.230850994,-6.00705816,"NoSignifi"]
[569,"REACTOME_TRANSCRIPTIONAL_REGULATION_OF_WHITE_ADIPOCYTE_DIFFERENTIATION",-1.594315666,-0.009754834,0.180234917,0.111030537,-0.225513393,-6.005120896,"NoSignifi"]
[567,"WP_ENDOCHONDRAL_OSSIFICATION",-1.602284786,-0.011678719,0.177745877,0.109257739,-0.161420078,-5.992454731,"NoSignifi"]
[568,"WP_ENDOCHONDRAL_OSSIFICATION_WITH_SKELETAL_DYSPLASIAS",-1.602284786,-0.011678719,0.177745877,0.109257739,-0.161420078,-5.992454731,"NoSignifi"]
[566,"WP_CANONICAL_AND_NONCANONICAL_NOTCH_SIGNALING",-1.608208133,-0.015279485,0.176011663,0.107954611,-0.047041951,-5.982999325,"NoSignifi"]
[565,"REACTOME_PHASE_3_RAPID_REPOLARISATION",-1.608859492,-0.024235903,0.175972527,0.107812067,0.154174064,-5.98195744,"NoSignifi"]
[564,"REACTOME_REGULATION_OF_GLYCOLYSIS_BY_FRUCTOSE_2_6_BISPHOSPHATE_METABOLISM",-1.6112462,-0.021199799,0.175218415,0.107291034,-0.245264682,-5.978136173,"NoSignifi"]
[563,"REACTOME_CELL_CELL_COMMUNICATION",-1.612196599,-0.01271528,0.174976736,0.107084112,-0.127715123,-5.976612954,"NoSignifi"]
[562,"REACTOME_MITOTIC_SPINDLE_CHECKPOINT",-1.615772397,-0.010373536,0.173804901,0.106308421,-0.121502556,-5.97087394,"NoSignifi"]
[561,"REACTOME_PARASITE_INFECTION",-1.623937701,-0.016816029,0.171597776,0.104553849,-0.184159151,-5.957721416,"NoSignifi"]
[560,"PID_BETA_CATENIN_DEG_PATHWAY",-1.624980473,-0.021022505,0.171432084,0.104331443,-0.186647157,-5.956036977,"NoSignifi"]
[559,"WP_PRIMARY_FOCAL_SEGMENTAL_GLOMERULOSCLEROSIS_FSGS",-1.625472246,-0.015885483,0.171432084,0.104226687,-0.159662565,-5.955242219,"NoSignifi"]
[558,"WP_PENTOSE_PHOSPHATE_METABOLISM",-1.630751436,-0.027405576,0.169692812,0.103107387,-0.213815417,-5.946695368,"NoSignifi"]
[557,"KEGG_P53_SIGNALING_PATHWAY",-1.635862074,-0.011461579,0.168017664,0.102032956,-0.17642502,-5.938395074,"NoSignifi"]
[556,"BIOCARTA_MET_PATHWAY",-1.636278529,-0.017758387,0.167967299,0.101945798,-0.200360106,-5.93771756,"NoSignifi"]
[555,"REACTOME_SUMO_IS_TRANSFERRED_FROM_E1_TO_E2_UBE2I_UBC9",-1.637050207,-0.034639631,0.16779458,0.101784452,-0.14869841,-5.936461691,"NoSignifi"]
[554,"REACTOME_TRANSCRIPTIONAL_ACTIVITY_OF_SMAD2_SMAD3_SMAD4_HETEROTRIMER",-1.641311313,-0.016818004,0.166609421,0.100897184,-0.272280085,-5.92951632,"NoSignifi"]
[553,"REACTOME_TRANSLOCATION_OF_SLC2A4_GLUT4_TO_THE_PLASMA_MEMBRANE",-1.642157252,-0.017027683,0.166412325,0.100721774,-0.182385905,-5.928135344,"NoSignifi"]
[552,"WP_DEVELOPMENT_OF_PULMONARY_DENDRITIC_CELLS_AND_MACROPHAGE_SUBSETS",-1.642226818,-0.023683463,0.166412325,0.100707361,-0.038866656,-5.928021748,"NoSignifi"]
[551,"REACTOME_TANDEM_PORE_DOMAIN_POTASSIUM_CHANNELS",-1.645831453,-0.016400232,0.165434419,0.099962731,0.246037468,-5.922129059,"NoSignifi"]
[550,"WP_SIGNAL_TRANSDUCTION_THROUGH_IL1R",-1.650330433,-0.01430947,0.164272819,0.099039524,-0.187437042,-5.914756264,"NoSignifi"]
[549,"REACTOME_ERK_MAPK_TARGETS",-1.65880683,-0.017215089,0.16168946,0.097318648,-0.225392693,-5.90081087,"NoSignifi"]
[548,"REACTOME_MITOTIC_G2_G2_M_PHASES",-1.659083671,-0.015489817,0.16168946,0.09726285,-0.133249464,-5.900354209,"NoSignifi"]
[547,"REACTOME_ACTIVATION_OF_MATRIX_METALLOPROTEINASES",-1.666598492,-0.0192995,0.159632456,0.095757967,-0.068303919,-5.887929168,"NoSignifi"]
[546,"REACTOME_CELL_JUNCTION_ORGANIZATION",-1.685145971,-0.013776627,0.154266608,0.092123508,-0.093313239,-5.857023059,"NoSignifi"]
[545,"BIOCARTA_AHSP_PATHWAY",-1.695580907,-0.019784812,0.151095436,0.090127995,-0.054268945,-5.839485168,"NoSignifi"]
[544,"BIOCARTA_CPSF_PATHWAY",-1.701028463,-0.022463422,0.149541186,0.089100154,-0.144920676,-5.830286635,"NoSignifi"]
[543,"WP_PRADERWILLI_AND_ANGELMAN_SYNDROME",-1.706932344,-0.011042003,0.147856715,0.087996906,-0.124195627,-5.820284352,"NoSignifi"]
[542,"WP_INTEGRATED_CANCER_PATHWAY",-1.707960197,-0.012720304,0.147619428,0.087805965,-0.197246671,-5.818539445,"NoSignifi"]
[541,"REACTOME_VEGFR2_MEDIATED_CELL_PROLIFERATION",-1.715434796,-0.021512957,0.145466638,0.086427467,-0.216585797,-5.805818896,"NoSignifi"]
[540,"BIOCARTA_NO1_PATHWAY",-1.732327173,-0.016201009,0.140730435,0.083376502,0.051328506,-5.77686684,"NoSignifi"]
[539,"REACTOME_EARLY_PHASE_OF_HIV_LIFE_CYCLE",-1.74319987,-0.027192294,0.137729415,0.081459364,-0.115695892,-5.758082394,"NoSignifi"]
[538,"WP_SPHINGOLIPID_PATHWAY",-1.745311891,-0.014618225,0.137263175,0.081091145,-0.094961532,-5.754419927,"NoSignifi"]
[537,"REACTOME_RHOF_GTPASE_CYCLE",-1.749876294,-0.017062684,0.136156856,0.080299985,-0.231203619,-5.746489671,"NoSignifi"]
[536,"BIOCARTA_CD40_PATHWAY",-1.749950114,-0.021407108,0.136156856,0.080287241,-0.225199597,-5.746361245,"NoSignifi"]
[535,"KEGG_ANTIGEN_PROCESSING_AND_PRESENTATION",-1.751116672,-0.02008874,0.135949432,0.080086075,-0.149712435,-5.744331054,"NoSignifi"]
[534,"WP_MICROTUBULE_CYTOSKELETON_REGULATION",-1.751915713,-0.016463054,0.13579357,0.079948521,-0.16830421,-5.742939684,"NoSignifi"]
[533,"REACTOME_RHOBTB_GTPASE_CYCLE",-1.752786328,-0.023761266,0.135616961,0.079798865,-0.20544751,-5.741422961,"NoSignifi"]
[532,"REACTOME_UPTAKE_AND_ACTIONS_OF_BACTERIAL_TOXINS",-1.754689206,-0.021246266,0.135139765,0.07947256,-0.12776816,-5.738105289,"NoSignifi"]
[531,"REACTOME_PHOSPHOLIPASE_C_MEDIATED_CASCADE_FGFR4",-1.757897863,-0.016177604,0.13428523,0.078924798,0.231780938,-5.732502865,"NoSignifi"]
[530,"WP_RESISTIN_AS_A_REGULATOR_OF_INFLAMMATION",-1.758749521,-0.013582834,0.134115597,0.078779926,-0.150479258,-5.731014127,"NoSignifi"]
[529,"REACTOME_NGF_STIMULATED_TRANSCRIPTION",-1.762888292,-0.0188938,0.133074901,0.078078976,-0.167051628,-5.723769131,"NoSignifi"]
[528,"BIOCARTA_SUMO_PATHWAY",-1.764521369,-0.038143051,0.132682063,0.077803796,-0.156134069,-5.72090573,"NoSignifi"]
[527,"PID_NFAT_TFPATHWAY",-1.77016761,-0.016056696,0.131599075,0.076858469,-0.115656333,-5.710985368,"NoSignifi"]
[526,"WP_HYPOTHESIZED_PATHWAYS_IN_PATHOGENESIS_OF_CARDIOVASCULAR_DISEASE",-1.778747336,-0.020189658,0.12946892,0.075439957,-0.26591129,-5.69585045,"NoSignifi"]
[525,"KEGG_BASAL_TRANSCRIPTION_FACTORS",-1.783405025,-0.013639132,0.128236911,0.074678888,-0.160265914,-5.687603587,"NoSignifi"]
[524,"REACTOME_ERKS_ARE_INACTIVATED",-1.786002428,-0.021930393,0.127660476,0.074257205,-0.255785699,-5.682995313,"NoSignifi"]
[523,"BIOCARTA_UCALPAIN_PATHWAY",-1.78879402,-0.029318447,0.126958583,0.073806169,-0.127157782,-5.67803506,"NoSignifi"]
[522,"WP_METABOLIC_REPROGRAMMING_IN_COLON_CANCER",-1.799148667,-0.020215273,0.124402672,0.072152712,-0.233829072,-5.659568924,"NoSignifi"]
[521,"REACTOME_SIGNALING_BY_ALK_IN_CANCER",-1.822773768,-0.022747885,0.118783728,0.068493682,-0.172941683,-5.617039053,"NoSignifi"]
[520,"REACTOME_REGULATION_OF_GENE_EXPRESSION_IN_ENDOCRINE_COMMITTED_NEUROG3_PROGENITOR_CELLS",-1.827338665,-0.008565149,0.117795078,0.067804577,0.782728665,-5.608757594,"NoSignifi"]
[519,"REACTOME_UPTAKE_AND_FUNCTION_OF_ANTHRAX_TOXINS",-1.827709713,-0.026492627,0.117767116,0.067748816,-0.263970927,-5.608083545,"NoSignifi"]
[518,"WP_NAD_METABOLISM",-1.835700263,-0.017242409,0.115899197,0.066557134,-0.073547083,-5.593534775,"NoSignifi"]
[517,"REACTOME_INFECTION_WITH_MYCOBACTERIUM_TUBERCULOSIS",-1.836112847,-0.024498723,0.115860825,0.066496075,-0.121220352,-5.592781846,"NoSignifi"]
[516,"REACTOME_RHOB_GTPASE_CYCLE",-1.851897478,-0.01370399,0.112577402,0.064194524,-0.161047063,-5.563849722,"NoSignifi"]
[515,"REACTOME_INTEGRATION_OF_PROVIRUS",-1.855955459,-0.032062119,0.11169056,0.063613586,-0.139852434,-5.55637185,"NoSignifi"]
[514,"REACTOME_TRANS_GOLGI_NETWORK_VESICLE_BUDDING",-1.859190595,-0.017759162,0.111014173,0.063153566,-0.171652174,-5.5503986,"NoSignifi"]
[513,"WP_RETT_SYNDROME_CAUSING_GENES",-1.860171168,-0.016227237,0.110835652,0.063014679,-0.215628353,-5.548586054,"NoSignifi"]
[512,"PID_S1P_S1P3_PATHWAY",-1.862076923,-0.023054097,0.110427566,0.062745471,-0.185030071,-5.545060627,"NoSignifi"]
[511,"BIOCARTA_DC_PATHWAY",-1.863430194,-0.011260165,0.110222823,0.062554886,0.523888522,-5.542555047,"NoSignifi"]
[510,"WP_HYPERTROPHY_MODEL",-1.87091217,-0.023681112,0.108510171,0.061509807,-0.191690711,-5.528669446,"NoSignifi"]
[509,"REACTOME_BETA_OXIDATION_OF_LAUROYL_COA_TO_DECANOYL_COA_COA",-1.875084419,-0.036714408,0.107682987,0.060933339,-0.201362292,-5.520902205,"NoSignifi"]
[508,"REACTOME_HUR_ELAVL1_BINDS_AND_STABILIZES_MRNA",-1.882256131,-0.030864659,0.106205371,0.059952914,-0.182529423,-5.507510748,"NoSignifi"]
[507,"REACTOME_RET_SIGNALING",-1.886327368,-0.014022945,0.10529261,0.059402196,-0.152279748,-5.499886024,"NoSignifi"]
[506,"WP_KYNURENINE_PATHWAY_AND_LINKS_TO_CELL_SENESCENCE",-1.888816927,-0.016885248,0.104761905,0.059067507,-0.078511523,-5.495215423,"NoSignifi"]
[505,"REACTOME_SIGNALING_BY_NTRKS",-1.891026379,-0.013815717,0.10442456,0.058771789,-0.166218913,-5.491065184,"NoSignifi"]
[504,"REACTOME_RECYCLING_PATHWAY_OF_L1",-1.909224413,-0.02164299,0.100419905,0.056382614,-0.145430238,-5.456698102,"NoSignifi"]
[503,"WP_METHIONINE_DE_NOVO_AND_SALVAGE_PATHWAY",-1.913720004,-0.020169076,0.09957039,0.055805028,-0.216140192,-5.448157649,"NoSignifi"]
[502,"BIOCARTA_EPONFKB_PATHWAY",-1.915935333,-0.027206402,0.09918501,0.055522225,-0.209399641,-5.443941742,"NoSignifi"]
[501,"PID_S1P_META_PATHWAY",-1.917359644,-0.021659867,0.099040102,0.055341034,-0.161792373,-5.441228623,"NoSignifi"]
[500,"REACTOME_PHENYLALANINE_AND_TYROSINE_METABOLISM",-1.917856182,-0.026436364,0.098986932,0.055277984,-0.000502999,-5.440282315,"NoSignifi"]
[499,"PID_VEGFR1_2_PATHWAY",-1.938416974,-0.018414895,0.094862804,0.052719309,-0.200928005,-5.400882956,"NoSignifi"]
[498,"PID_PDGFRB_PATHWAY",-1.946880219,-0.017578644,0.093189598,0.051695274,-0.181339634,-5.38454379,"NoSignifi"]
[497,"REACTOME_2_LTR_CIRCLE_FORMATION",-1.948007398,-0.036110074,0.093002487,0.051560153,-0.14047157,-5.382362304,"NoSignifi"]
[496,"REACTOME_METABOLISM_OF_NITRIC_OXIDE_NOS3_ACTIVATION_AND_REGULATION",-1.951062829,-0.025639432,0.092400639,0.051195369,-0.168101318,-5.376442652,"NoSignifi"]
[495,"REACTOME_SIGNALING_BY_VEGF",-1.952007326,-0.016809407,0.092253992,0.051083046,-0.168712338,-5.374610895,"NoSignifi"]
[494,"REACTOME_SIGNAL_TRANSDUCTION_BY_L1",-1.956554811,-0.025558806,0.091605159,0.050545126,-0.214317578,-5.365779145,"NoSignifi"]
[493,"REACTOME_POSTMITOTIC_NUCLEAR_PORE_COMPLEX_NPC_REFORMATION",-1.956574097,-0.019100316,0.091605159,0.050542855,-0.189689459,-5.365741647,"NoSignifi"]
[492,"REACTOME_NEGATIVE_REGULATION_OF_MAPK_PATHWAY",-1.956740862,-0.020506606,0.091605159,0.05052322,-0.19120012,-5.365417376,"NoSignifi"]
[491,"WP_EXTRACELLULAR_VESICLES_IN_THE_CROSSTALK_OF_CARDIAC_CELLS",-1.959721281,-0.024550115,0.091109944,0.050173378,-0.119697853,-5.359617401,"NoSignifi"]
[490,"PID_HIF2PATHWAY",-1.961787465,-0.022524517,0.090782754,0.049932043,-0.201978132,-5.355591392,"NoSignifi"]
[489,"WP_MTHFR_DEFICIENCY",-1.965971618,-0.016224565,0.090009865,0.049446309,-0.13533207,-5.347425525,"NoSignifi"]
[488,"REACTOME_L1CAM_INTERACTIONS",-1.967717966,-0.015892238,0.089697959,0.049244753,-0.115146915,-5.344012196,"NoSignifi"]
[487,"KEGG_TYPE_I_DIABETES_MELLITUS",-1.96912167,-0.01798774,0.089458658,0.049083245,0.011623167,-5.341266395,"NoSignifi"]
[486,"KEGG_GLIOMA",-1.971176532,-0.014897553,0.089083892,0.048847618,-0.195856135,-5.33724334,"NoSignifi"]
[485,"PID_ERBB4_PATHWAY",-1.972241527,-0.016914805,0.088916479,0.048725871,-0.181970143,-5.335156624,"NoSignifi"]
[484,"KEGG_SMALL_CELL_LUNG_CANCER",-1.974903191,-0.013551672,0.08841761,0.048422713,-0.131142948,-5.329936541,"NoSignifi"]
[483,"REACTOME_G_ALPHA_12_13_SIGNALLING_EVENTS",-1.984551126,-0.012342507,0.086648469,0.047337089,-0.077772139,-5.310956142,"NoSignifi"]
[482,"PID_ILK_PATHWAY",-1.985174508,-0.022627265,0.086574746,0.047267654,-0.211807741,-5.309726592,"NoSignifi"]
[481,"REACTOME_METABOLISM_OF_STEROID_HORMONES",-1.987029342,-0.014651991,0.086250477,0.04706156,0.045367571,-5.306065872,"NoSignifi"]
[480,"REACTOME_CLATHRIN_MEDIATED_ENDOCYTOSIS",-1.987815752,-0.015223823,0.08614393,0.04697441,-0.174242835,-5.304512778,"NoSignifi"]
[479,"BIOCARTA_RACCYCD_PATHWAY",-1.99210065,-0.021016649,0.085488702,0.046501938,-0.260456993,-5.296039708,"NoSignifi"]
[478,"BIOCARTA_NKT_PATHWAY",-1.992892607,-0.020074073,0.085434776,0.046415053,0.00047419,-5.294471682,"NoSignifi"]
[477,"REACTOME_SUMO_IS_CONJUGATED_TO_E1_UBA2_SAE1",-2.024599552,-0.044723656,0.079729931,0.04304718,-0.17345137,-5.231184074,"Down"]
[476,"REACTOME_BMAL1_CLOCK_NPAS2_ACTIVATES_CIRCADIAN_GENE_EXPRESSION",-2.030888637,-0.020527531,0.078686533,0.042404329,-0.300036213,-5.218512736,"Down"]
[475,"BIOCARTA_INFLAM_PATHWAY",-2.031988617,-0.018137475,0.07852853,0.042292731,0.011845849,-5.21629246,"Down"]
[474,"REACTOME_PROCESSING_OF_SMDT1",-2.037542052,-0.025290834,0.077635075,0.041733102,-0.266536442,-5.205064747,"Down"]
[473,"REACTOME_NEF_MEDIATED_CD4_DOWN_REGULATION",-2.041044256,-0.035369259,0.077032826,0.041383414,-0.189693065,-5.197968442,"Down"]
[472,"WP_SARSCOV2_REPLICATION_ORGANELLE_FORMATION",-2.053565636,-0.029084593,0.074978313,0.040153425,-0.250163197,-5.172497886,"Down"]
[471,"REACTOME_MITOCHONDRIAL_CALCIUM_ION_TRANSPORT",-2.058271781,-0.02448737,0.074245236,0.039699227,-0.210467137,-5.16288471,"Down"]
[470,"WP_PRION_DISEASE_PATHWAY",-2.065342237,-0.025186262,0.073147336,0.039025053,-0.21278923,-5.148400808,"Down"]
[469,"REACTOME_HEME_SIGNALING",-2.070443561,-0.017046318,0.072384074,0.038544702,-0.238645992,-5.137919986,"Down"]
[468,"WP_CLEAR_CELL_RENAL_CELL_CARCINOMA_PATHWAYS",-2.081801402,-0.018816832,0.070677774,0.037493262,-0.174491546,-5.114492516,"Down"]
[467,"REACTOME_REGULATION_OF_GLUCOKINASE_BY_GLUCOKINASE_REGULATORY_PROTEIN",-2.102319847,-0.016803633,0.067773154,0.035655664,-0.218442009,-5.071846326,"Down"]
[466,"BIOCARTA_AKT_PATHWAY",-2.103185487,-0.023910608,0.067672391,0.035579859,-0.230367618,-5.070038001,"Down"]
[465,"PID_CERAMIDE_PATHWAY",-2.108207095,-0.016545808,0.06696986,0.035142823,-0.185827692,-5.059533218,"Down"]
[464,"REACTOME_CGMP_EFFECTS",-2.11166649,-0.020288248,0.066712758,0.034844423,0.103527314,-5.052281948,"Down"]
[463,"REACTOME_SUMOYLATION_OF_DNA_METHYLATION_PROTEINS",-2.112229362,-0.022580932,0.066694351,0.034796076,-0.176775236,-5.051100987,"Down"]
[462,"REACTOME_BETA_OXIDATION_OF_OCTANOYL_COA_TO_HEXANOYL_COA",-2.11230249,-0.037821886,0.066694351,0.034789799,-0.253670673,-5.050947536,"Down"]
[461,"PID_ERB_GENOMIC_PATHWAY",-2.1251097,-0.025155861,0.065108044,0.033705309,-0.253084212,-5.023991177,"Down"]
[460,"KEGG_ALANINE_ASPARTATE_AND_GLUTAMATE_METABOLISM",-2.127321186,-0.016129875,0.064836393,0.033521005,-0.03317332,-5.019320065,"Down"]
[459,"PID_IFNG_PATHWAY",-2.134272088,-0.01911323,0.063934714,0.032947326,-0.21463259,-5.004606854,"Down"]
[458,"PID_AURORA_A_PATHWAY",-2.140724878,-0.020846749,0.062957379,0.032422308,-0.180359504,-4.990905259,"Down"]
[457,"REACTOME_SEMA4D_INDUCED_CELL_MIGRATION_AND_GROWTH_CONE_COLLAPSE",-2.152377434,-0.033830922,0.061352284,0.031492382,-0.183557773,-4.966058403,"Down"]
[456,"REACTOME_SIGNALING_BY_TGF_BETA_RECEPTOR_COMPLEX",-2.155167047,-0.01978969,0.060965258,0.031273186,-0.216913388,-4.960090173,"Down"]
[455,"REACTOME_RNA_POLYMERASE_II_TRANSCRIPTION_TERMINATION",-2.155253168,-0.02102512,0.060965258,0.031266439,-0.201814322,-4.959905798,"Down"]
[454,"WP_SMALL_CELL_LUNG_CANCER",-2.160213893,-0.01438044,0.060317489,0.030879954,-0.1292819,-4.949273162,"Down"]
[453,"REACTOME_MITOCHONDRIAL_FATTY_ACID_BETA_OXIDATION_OF_SATURATED_FATTY_ACIDS",-2.169617086,-0.03039406,0.059025002,0.030158615,-0.195653213,-4.929051946,"Down"]
[452,"REACTOME_CATION_COUPLED_CHLORIDE_COTRANSPORTERS",-2.171617656,-0.024800282,0.058767067,0.030007031,0.009057203,-4.92473852,"Down"]
[451,"REACTOME_P2Y_RECEPTORS",-2.175605632,-0.016953162,0.058255965,0.029706814,0.372881233,-4.916128248,"Down"]
[450,"PID_AR_PATHWAY",-2.184766283,-0.019298394,0.057035784,0.029026969,-0.205062452,-4.896290348,"Down"]
[449,"BIOCARTA_PRION_PATHWAY",-2.191493557,-0.035547175,0.056145949,0.028536287,-0.17317419,-4.881669243,"Down"]
[448,"PID_REELIN_PATHWAY",-2.191930155,-0.021091453,0.056120973,0.028504691,-0.141821213,-4.880718791,"Down"]
[447,"REACTOME_CHK1_CHK2_CDS1_MEDIATED_INACTIVATION_OF_CYCLIN_B_CDK1_COMPLEX",-2.19510521,-0.041605383,0.055744293,0.028275819,-0.191510668,-4.873801199,"Down"]
[446,"REACTOME_BETA_OXIDATION_OF_DECANOYL_COA_TO_OCTANOYL_COA_COA",-2.200432109,-0.03599544,0.05506743,0.027895391,-0.222461017,-4.862172937,"Down"]
[445,"REACTOME_GAP_JUNCTION_ASSEMBLY",-2.208634741,-0.024775753,0.053999875,0.027318226,-0.015425486,-4.84421231,"Down"]
[444,"KEGG_ETHER_LIPID_METABOLISM",-2.209328953,-0.021781719,0.053964954,0.027269855,-0.019782723,-4.8426892,"Down"]
[443,"WP_PPARALPHA_PATHWAY",-2.218421396,-0.02451427,0.052879484,0.026643121,-0.191275176,-4.822696296,"Down"]
[442,"REACTOME_RUNX1_REGULATES_GENES_INVOLVED_IN_MEGAKARYOCYTE_DIFFERENTIATION_AND_PLATELET_FUNCTION",-2.221798776,-0.020046685,0.052526269,0.026413513,-0.183584385,-4.815249142,"Down"]
[441,"PID_PI3KCI_AKT_PATHWAY",-2.223573187,-0.024349063,0.052322791,0.026293568,-0.222021883,-4.811332033,"Down"]
[440,"REACTOME_SEMA4D_IN_SEMAPHORIN_SIGNALING",-2.233513066,-0.033236379,0.051174493,0.025630337,-0.176839379,-4.789331689,"Down"]
[439,"WP_PHOSPHODIESTERASES_IN_NEURONAL_FUNCTION",-2.235248769,-0.014870786,0.050980529,0.025516021,0.219177941,-4.785479974,"Down"]
[438,"REACTOME_LOSS_OF_MECP2_BINDING_ABILITY_TO_THE_NCOR_SMRT_COMPLEX",-2.237141686,-0.035320616,0.05076661,0.025391854,-0.31618589,-4.781275992,"Down"]
[437,"PID_WNT_NONCANONICAL_PATHWAY",-2.23926587,-0.02325472,0.050557367,0.025253141,-0.16849891,-4.776554173,"Down"]
[436,"BIOCARTA_FOSB_PATHWAY",-2.248364879,-0.049461961,0.049482718,0.02466636,-0.105426588,-4.756277672,"Down"]
[435,"WP_SELENIUM_MICRONUTRIENT_NETWORK",-2.251371705,-0.015779452,0.049165416,0.024475071,-0.086130163,-4.749559192,"Down"]
[434,"REACTOME_HS_GAG_BIOSYNTHESIS",-2.25614309,-0.019632861,0.048758893,0.024174163,-0.147540839,-4.738879635,"Down"]
[433,"BIOCARTA_IL1R_PATHWAY",-2.259275733,-0.020582945,0.048429749,0.023978353,-0.171839671,-4.731855762,"Down"]
[432,"WP_SOMATROPH_AXIS_GH_AND_ITS_RELATIONSHIP_TO_DIETARY_RESTRICTION_AND_AGING",-2.268525752,-0.03970677,0.047471918,0.023408181,-0.237430081,-4.711059217,"Down"]
[430,"REACTOME_MITOCHONDRIAL_UNCOUPLING",-2.277719273,-0.014879312,0.046537135,0.022853197,0.30097464,-4.690305951,"Down"]
[431,"REACTOME_THE_FATTY_ACID_CYCLING_MODEL",-2.277719273,-0.014879312,0.046537135,0.022853197,0.30097464,-4.690305951,"Down"]
[429,"WP_MFAP5_EFFECT_ON_PERMEABILITY_AND_MOTILITY_OF_ENDOTHELIAL_CELLS_VIA_CYTOSKELETON_REARRANGEMENT",-2.282784877,-0.032035106,0.046019131,0.022552319,-0.280323599,-4.678835293,"Down"]
[428,"REACTOME_DISINHIBITION_OF_SNARE_FORMATION",-2.286884631,-0.042826754,0.045590063,0.022311338,-0.253148705,-4.669533169,"Down"]
[427,"REACTOME_WNT5A_DEPENDENT_INTERNALIZATION_OF_FZD4",-2.29397767,-0.034541842,0.044841527,0.021899702,-0.170101423,-4.653400236,"Down"]
[426,"REACTOME_SYNTHESIS_OF_PIPS_AT_THE_ER_MEMBRANE",-2.295097344,-0.033550529,0.044740577,0.021835331,-0.227438783,-4.650849025,"Down"]
[425,"REACTOME_PTK6_REGULATES_CELL_CYCLE",-2.314652819,-0.044480327,0.042689283,0.020737351,-0.250557795,-4.606091674,"Down"]
[424,"REACTOME_CHYLOMICRON_ASSEMBLY",-2.325049083,-0.043722083,0.041622706,0.020173484,-0.115515239,-4.582143619,"Down"]
[423,"KEGG_CIRCADIAN_RHYTHM_MAMMAL",-2.331067146,-0.030480282,0.041040029,0.019853236,-0.318045803,-4.568232093,"Down"]
[422,"WP_EDA_SIGNALING_IN_HAIR_FOLLICLE_DEVELOPMENT",-2.3531399,-0.026333331,0.038968361,0.018716363,0.048478507,-4.516902022,"Down"]
[421,"REACTOME_ETHANOL_OXIDATION",-2.358290495,-0.030419444,0.038460382,0.018459429,0.091268981,-4.504855132,"Down"]
[420,"REACTOME_EFFECTS_OF_PIP2_HYDROLYSIS",-2.360872967,-0.02122582,0.038248086,0.01833177,-0.033087548,-4.498805052,"Down"]
[419,"PID_CIRCADIAN_PATHWAY",-2.366080398,-0.029524845,0.037779571,0.018076703,-0.228801481,-4.486585331,"Down"]
[418,"REACTOME_SHC1_EVENTS_IN_ERBB2_SIGNALING",-2.374363601,-0.024234902,0.036986728,0.017677388,-0.139476674,-4.46709288,"Down"]
[417,"WP_GLYCOLYSIS_IN_SENESCENCE",-2.377807648,-0.045841055,0.036716914,0.017513649,-0.209080555,-4.458968243,"Down"]
[416,"REACTOME_DSCAM_INTERACTIONS",-2.377817027,-0.030373406,0.036716914,0.017513205,-0.127977764,-4.4589461,"Down"]
[415,"REACTOME_SIGNALING_BY_NODAL",-2.383713901,-0.024502316,0.036190612,0.017235946,-0.188077785,-4.445007916,"Down"]
[414,"REACTOME_AMINO_ACIDS_REGULATE_MTORC1",-2.388898595,-0.020502003,0.035710711,0.016995364,-0.156673441,-4.432724729,"Down"]
[413,"REACTOME_CREATION_OF_C4_AND_C2_ACTIVATORS",-2.389942884,-0.037002035,0.035634864,0.016947265,0.149128103,-4.430247469,"Down"]
[412,"REACTOME_DEFECTIVE_INTRINSIC_PATHWAY_FOR_APOPTOSIS",-2.392129613,-0.030003205,0.035474144,0.016846933,-0.139301534,-4.425056626,"Down"]
[411,"WP_MIR517_RELATIONSHIP_WITH_ARCN1_AND_USP1",-2.39337677,-0.045906858,0.035403657,0.016789944,-0.28882374,-4.422094021,"Down"]
[410,"KEGG_AUTOIMMUNE_THYROID_DISEASE",-2.396817538,-0.025014763,0.035149572,0.016633597,0.026159798,-4.413912564,"Down"]
[409,"WP_NEUROINFLAMMATION_AND_GLUTAMATERGIC_SIGNALING",-2.398612411,-0.0117468,0.035003215,0.016552547,-0.094301803,-4.409640078,"Down"]
[408,"WP_REGULATION_OF_ACTIN_CYTOSKELETON",-2.402831337,-0.018929533,0.034627899,0.016363403,-0.149288184,-4.399584899,"Down"]
[407,"REACTOME_APC_CDC20_MEDIATED_DEGRADATION_OF_NEK2A",-2.402967297,-0.027487812,0.034627899,0.016357339,-0.1606611,-4.399260568,"Down"]
[406,"BIOCARTA_LEPTIN_PATHWAY",-2.413116539,-0.028739351,0.03381352,0.015910235,-0.081334286,-4.374998058,"Down"]
[405,"REACTOME_RECRUITMENT_OF_MITOTIC_CENTROSOME_PROTEINS_AND_COMPLEXES",-2.415942833,-0.018611705,0.03362522,0.015787658,-0.153555213,-4.368223502,"Down"]
[404,"REACTOME_ION_CHANNEL_TRANSPORT",-2.417202404,-0.009182335,0.033533499,0.015733299,-0.033170351,-4.365201803,"Down"]
[403,"REACTOME_TETRAHYDROBIOPTERIN_BH4_SYNTHESIS_RECYCLING_SALVAGE_AND_REGULATION",-2.418156791,-0.035092392,0.033469972,0.01569222,-0.040085302,-4.362911195,"Down"]
[402,"REACTOME_NUCLEAR_EVENTS_STIMULATED_BY_ALK_SIGNALING_IN_CANCER",-2.423077453,-0.03829851,0.033116585,0.01548192,-0.143557987,-4.35108694,"Down"]
[401,"WP_GALANIN_RECEPTOR_PATHWAY",-2.424705591,-0.02722556,0.032992686,0.015412885,-0.183365812,-4.347169294,"Down"]
[400,"PID_PRL_SIGNALING_EVENTS_PATHWAY",-2.430473518,-0.034983839,0.032520721,0.015170495,-0.182481399,-4.333269397,"Down"]
[399,"KEGG_REGULATION_OF_ACTIN_CYTOSKELETON",-2.438016466,-0.017929782,0.031898146,0.014858584,-0.134321164,-4.315042422,"Down"]
[398,"REACTOME_YAP1_AND_WWTR1_TAZ_STIMULATED_GENE_EXPRESSION",-2.461505633,-0.036000744,0.030085875,0.013923204,-0.181172935,-4.257923071,"Down"]
[397,"WP_ALANINE_AND_ASPARTATE_METABOLISM",-2.484282856,-0.02382532,0.028357969,0.013066252,0.002154727,-4.202015275,"Down"]
[396,"WP_PEROXIREDOXIN_2_INDUCED_OVARIAN_FAILURE",-2.488235349,-0.045583399,0.028066272,0.012922396,-0.214549828,-4.192261597,"Down"]
[395,"REACTOME_REGULATION_OF_PLK1_ACTIVITY_AT_G2_M_TRANSITION",-2.491694651,-0.023207719,0.027856453,0.012797643,-0.140241655,-4.183712336,"Down"]
[394,"BIOCARTA_PDZS_PATHWAY",-2.495385634,-0.02817038,0.027589509,0.012665712,-0.082062559,-4.174577491,"Down"]
[393,"REACTOME_INTERLEUKIN_2_FAMILY_SIGNALING",-2.49547779,-0.018435197,0.027589509,0.012662434,-0.064807458,-4.174349241,"Down"]
[392,"REACTOME_REGULATION_OF_INSULIN_SECRETION",-2.497267148,-0.021031297,0.027504563,0.012598924,-0.099634478,-4.169915749,"Down"]
[391,"REACTOME_MECP2_REGULATES_TRANSCRIPTION_FACTORS",-2.500467432,-0.041023414,0.027298272,0.01248604,-0.288903408,-4.161978527,"Down"]
[390,"WP_G1_TO_S_CELL_CYCLE_CONTROL",-2.50229295,-0.01503671,0.027178385,0.012422051,-0.17293781,-4.157446425,"Down"]
[389,"REACTOME_INTERLEUKIN_RECEPTOR_SHC_SIGNALING",-2.507585454,-0.022287344,0.0268156,0.012238174,-0.088011388,-4.144288476,"Down"]
[388,"REACTOME_INTEGRIN_SIGNALING",-2.51843036,-0.030124391,0.026083496,0.011868913,-0.20752672,-4.117240161,"Down"]
[387,"KEGG_CHEMOKINE_SIGNALING_PATHWAY",-2.518535549,-0.011316902,0.026083496,0.01186538,-0.082221207,-4.116977239,"Down"]
[386,"WP_COMMON_PATHWAYS_UNDERLYING_DRUG_ADDICTION",-2.519670516,-0.027860678,0.026049942,0.011827323,-0.147414683,-4.114139696,"Down"]
[385,"WP_HIF1A_AND_PPARG_REGULATION_OF_GLYCOLYSIS",-2.522820712,-0.052868828,0.025895377,0.011722259,-0.149531812,-4.106257197,"Down"]
[384,"REACTOME_PYRUVATE_METABOLISM",-2.523720778,-0.025550806,0.025848633,0.011692393,-0.213435961,-4.104003231,"Down"]
[383,"KEGG_PROGESTERONE_MEDIATED_OOCYTE_MATURATION",-2.526750393,-0.014825493,0.025684863,0.01159236,-0.147495889,-4.096410538,"Down"]
[382,"WP_PANCREATIC_ADENOCARCINOMA_PATHWAY",-2.526841503,-0.01941829,0.025684863,0.011589363,-0.209060518,-4.096182061,"Down"]
[381,"BIOCARTA_CTBP1_PATHWAY",-2.545339812,-0.042052027,0.024452634,0.010995038,-0.166568569,-4.049624428,"Down"]
[380,"WP_ALLOGRAFT_REJECTION",-2.555104437,-0.016129418,0.023850983,0.010692374,0.027132798,-4.024912234,"Down"]
[379,"PID_ARF6_PATHWAY",-2.556989965,-0.020424168,0.023740373,0.010634792,-0.118545359,-4.020129535,"Down"]
[378,"WP_ONECARBON_METABOLISM_AND_RELATED_PATHWAYS",-2.565619898,-0.019154229,0.023194751,0.010374749,-0.060706141,-3.998194739,"Down"]
[377,"REACTOME_SEMA4D_MEDIATED_INHIBITION_OF_CELL_ATTACHMENT_AND_MIGRATION",-2.566049544,-0.049855692,0.023183598,0.010361952,-0.144986034,-3.997100785,"Down"]
[376,"WP_MBDNF_AND_PROBDNF_REGULATION_OF_GABA_NEUROTRANSMISSION",-2.567690932,-0.024739518,0.023091906,0.010313192,-0.117993985,-3.992919849,"Down"]
[375,"WP_CALORIC_RESTRICTION_AND_AGING",-2.56961058,-0.03512026,0.022982134,0.010256426,-0.26514858,-3.988026762,"Down"]
[374,"REACTOME_RHOBTB2_GTPASE_CYCLE",-2.577113211,-0.039174253,0.022524956,0.010037223,-0.214218377,-3.968868098,"Down"]
[373,"PID_EPHA2_FWD_PATHWAY",-2.588311971,-0.030673878,0.021890851,0.009717798,-0.221157026,-3.940167835,"Down"]
[372,"REACTOME_PROCESSING_OF_CAPPED_INTRONLESS_PRE_MRNA",-2.609713576,-0.030495016,0.020682168,0.009132476,-0.175759693,-3.88497593,"Down"]
[371,"REACTOME_IKBA_VARIANT_LEADS_TO_EDA_ID",-2.612568438,-0.040871246,0.020542184,0.009056827,-0.258905961,-3.877579508,"Down"]
[370,"WP_NEPHROTIC_SYNDROME",-2.612858762,-0.021474388,0.020540498,0.009049165,-0.111352116,-3.876826881,"Down"]
[369,"PID_MYC_ACTIV_PATHWAY",-2.622960075,-0.025824512,0.020004709,0.00878617,-0.191689423,-3.850588882,"Down"]
[368,"REACTOME_LYSOSOME_VESICLE_BIOGENESIS",-2.628166613,-0.029460117,0.019732453,0.008653302,-0.123025607,-3.837025731,"Down"]
[367,"REACTOME_ACTIVATION_OF_NMDA_RECEPTORS_AND_POSTSYNAPTIC_EVENTS",-2.653763155,-0.015640757,0.018400635,0.008025875,-0.123027803,-3.76995785,"Down"]
[366,"PID_EPHA_FWDPATHWAY",-2.654789978,-0.022629145,0.018359108,0.008001578,-0.093572185,-3.767253913,"Down"]
[365,"WP_UREA_CYCLE_AND_ASSOCIATED_PATHWAYS",-2.66000079,-0.021363244,0.018106517,0.007879293,0.058919177,-3.753516262,"Down"]
[364,"REACTOME_GENE_SILENCING_BY_RNA",-2.671402288,-0.018431805,0.017559402,0.007617551,-0.171898128,-3.72336439,"Down"]
[363,"REACTOME_NEF_MEDIATED_CD8_DOWN_REGULATION",-2.67242738,-0.047726819,0.017533272,0.007594405,-0.204840662,-3.720647209,"Down"]
[362,"PID_IL12_2PATHWAY",-2.703221518,-0.017702125,0.016107118,0.006927851,-0.013964706,-3.638539705,"Down"]
[361,"REACTOME_REGULATION_OF_BETA_CELL_DEVELOPMENT",-2.71649845,-0.023035808,0.015513979,0.006657059,-0.083158458,-3.602850942,"Down"]
[360,"BIOCARTA_NOS1_PATHWAY",-2.724766256,-0.03311968,0.015179963,0.006493282,-0.074384426,-3.580539188,"Down"]
[359,"KEGG_MELANOMA",-2.726020124,-0.018392578,0.01514469,0.006468763,-0.191972146,-3.577149585,"Down"]
[358,"REACTOME_ARMS_MEDIATED_ACTIVATION",-2.729456913,-0.047708727,0.015001968,0.006401985,-0.241241948,-3.567850923,"Down"]
[357,"PID_HIF1_TFPATHWAY",-2.732191297,-0.028815861,0.01489026,0.006349299,-0.227125309,-3.560444404,"Down"]
[356,"WP_CELL_DIFFERENTIATION_INDEX",-2.732870229,-0.044186333,0.014871471,0.006336278,-0.156464313,-3.558604267,"Down"]
[355,"WP_MELATONIN_METABOLISM_AND_EFFECTS",-2.74040032,-0.022802994,0.014570842,0.006193467,-0.177550793,-3.538164734,"Down"]
[354,"KEGG_T_CELL_RECEPTOR_SIGNALING_PATHWAY",-2.742075875,-0.016376708,0.01453156,0.006162086,-0.133266471,-3.533609051,"Down"]
[353,"REACTOME_G_PROTEIN_BETA_GAMMA_SIGNALLING",-2.743478736,-0.026997154,0.014481364,0.006135923,-0.064329266,-3.529792676,"Down"]
[352,"WP_MAMMARY_GLAND_DEVELOPMENT_PATHWAY_EMBRYONIC_DEVELOPMENT_STAGE_1_OF_4",-2.754356688,-0.034876795,0.014044023,0.005936426,-0.18939149,-3.500134301,"Down"]
[351,"REACTOME_NOSTRIN_MEDIATED_ENOS_TRAFFICKING",-2.754720779,-0.051115,0.014039655,0.005929851,-0.019972309,-3.499139604,"Down"]
[350,"REACTOME_LDL_CLEARANCE",-2.756961293,-0.034932325,0.013955331,0.005889535,-0.146154412,-3.493015653,"Down"]
[349,"REACTOME_TRANSCRIPTIONAL_REGULATION_BY_VENTX",-2.782502431,-0.024530153,0.012975951,0.005447112,-0.207531317,-3.422855537,"Down"]
[348,"REACTOME_CYCLIN_A_B1_B2_ASSOCIATED_EVENTS_DURING_G2_M_TRANSITION",-2.792937708,-0.022878131,0.012630609,0.005275162,-0.094383372,-3.394005736,"Down"]
[347,"PID_FAK_PATHWAY",-2.803442568,-0.028316995,0.012326906,0.005107035,-0.208261609,-3.364855383,"Down"]
[346,"WP_ULTRACONSERVED_REGION_339_MODULATION_OF_TUMOR_SUPPRESSOR_MICRORNAS_IN_CANCER",-2.80779795,-0.062437528,0.012182522,0.005038762,-0.256340828,-3.352737631,"Down"]
[345,"REACTOME_ACTIVATION_OF_ATR_IN_RESPONSE_TO_REPLICATION_STRESS",-2.81464207,-0.019946959,0.011966096,0.004933143,-0.02754773,-3.333657899,"Down"]
[344,"WP_IRON_METABOLISM_IN_PLACENTA",-2.833583787,-0.035115049,0.011328476,0.0046512,-0.16163215,-3.280612876,"Down"]
[343,"BIOCARTA_AGR_PATHWAY",-2.842498992,-0.027713475,0.011063124,0.004523622,-0.069555949,-3.255524336,"Down"]
[342,"REACTOME_MAP2K_AND_MAPK_ACTIVATION",-2.851623773,-0.034265348,0.0107963,0.004396338,-0.153473554,-3.229765097,"Down"]
[341,"REACTOME_SYNTHESIS_OF_VERY_LONG_CHAIN_FATTY_ACYL_COAS",-2.855462502,-0.026589996,0.010684877,0.004343768,-0.14731727,-3.218903913,"Down"]
[340,"REACTOME_SYNTHESIS_OF_GDP_MANNOSE",-2.857145858,-0.04550185,0.010637429,0.004320896,-0.255907662,-3.214136507,"Down"]
[339,"REACTOME_ACYL_CHAIN_REMODELLING_OF_PE",-2.862449538,-0.022414339,0.010479152,0.004249545,0.074533111,-3.199097823,"Down"]
[338,"PID_NETRIN_PATHWAY",-2.889995897,-0.029207352,0.00966799,0.003895875,-0.18462824,-3.120544877,"Down"]
[337,"REACTOME_CREB_PHOSPHORYLATION",-2.89441776,-0.042654317,0.009544684,0.003841663,-0.286440627,-3.107865746,"Down"]
[336,"REACTOME_GLYCOLYSIS",-2.9139985,-0.024832554,0.009013754,0.003609752,-0.2181266,-3.051489537,"Down"]
[335,"BIOCARTA_VOBESITY_PATHWAY",-2.914609296,-0.046992655,0.009003785,0.003602727,-0.001645863,-3.049724893,"Down"]
[334,"REACTOME_INTERLEUKIN_18_SIGNALING",-2.91507466,-0.024453261,0.008998004,0.003597383,0.283590442,-3.048380173,"Down"]
[333,"KEGG_PANCREATIC_CANCER",-2.91763858,-0.022614809,0.008932211,0.003568071,-0.196368348,-3.040967613,"Down"]
[332,"WP_EXRNA_MECHANISM_OF_ACTION_AND_BIOGENESIS",-2.920596161,-0.048753679,0.008869253,0.003534528,-0.255066979,-3.032408919,"Down"]
[331,"REACTOME_IRF3_MEDIATED_ACTIVATION_OF_TYPE_1_IFN",-2.92394546,-0.049607688,0.008791079,0.003496889,-0.158955204,-3.022706288,"Down"]
[330,"KEGG_PENTOSE_PHOSPHATE_PATHWAY",-2.925635721,-0.028218582,0.008751086,0.003478034,-0.230342643,-3.017805562,"Down"]
[329,"WP_SECRETION_OF_HYDROCHLORIC_ACID_IN_PARIETAL_CELLS",-2.931108361,-0.013992442,0.008613671,0.003417617,0.466866126,-3.001918991,"Down"]
[328,"BIOCARTA_MALATEX_PATHWAY",-2.933471287,-0.04468696,0.00856321,0.003391827,-0.304411485,-2.995050539,"Down"]
[327,"REACTOME_RETROGRADE_NEUROTROPHIN_SIGNALLING",-2.942149702,-0.042328273,0.008363462,0.003298624,-0.164815071,-2.96977743,"Down"]
[326,"WP_OSX_AND_MIRNAS_IN_TOOTH_DEVELOPMENT",-2.948686421,-0.037712205,0.008196393,0.00322997,-0.049058681,-2.950692477,"Down"]
[325,"REACTOME_CHOLINE_CATABOLISM",-2.950793142,-0.06522029,0.008147917,0.003208122,-0.024309077,-2.944532641,"Down"]
[324,"REACTOME_SHC1_EVENTS_IN_ERBB4_SIGNALING",-2.96233621,-0.0349402,0.007910827,0.003090791,-0.144038556,-2.910704508,"Down"]
[323,"REACTOME_NEUROTRANSMITTER_CLEARANCE",-2.973700883,-0.044275745,0.007657995,0.002979112,0.013262106,-2.87727134,"Down"]
[322,"REACTOME_APC_C_CDC20_MEDIATED_DEGRADATION_OF_CYCLIN_B",-2.97648246,-0.039058074,0.007595765,0.002952345,-0.188632716,-2.869069038,"Down"]
[321,"REACTOME_RECRUITMENT_OF_NUMA_TO_MITOTIC_CENTROSOMES",-2.992172514,-0.022930358,0.007242892,0.002805431,-0.13710191,-2.82265997,"Down"]
[320,"REACTOME_G0_AND_EARLY_G1",-3.008691437,-0.024624846,0.006880217,0.002658002,-0.11626958,-2.773538026,"Down"]
[319,"WP_EXTRACELLULAR_VESICLEMEDIATED_SIGNALING_IN_RECIPIENT_CELLS",-3.016044133,-0.028212185,0.006739835,0.002594689,-0.234362318,-2.751587326,"Down"]
[318,"REACTOME_PREGNENOLONE_BIOSYNTHESIS",-3.023148812,-0.037865618,0.006624908,0.002534825,-0.117224628,-2.730326644,"Down"]
[317,"WP_MFAP5MEDIATED_OVARIAN_CANCER_CELL_MOTILITY_AND_INVASIVENESS",-3.023695582,-0.041830937,0.006618831,0.002530271,-0.270167364,-2.728688387,"Down"]
[316,"WP_METASTATIC_BRAIN_TUMOR",-3.036508182,-0.051378122,0.006362028,0.00242567,-0.277049735,-2.69021469,"Down"]
[315,"REACTOME_CREB1_PHOSPHORYLATION_THROUGH_NMDA_RECEPTOR_MEDIATED_ACTIVATION_OF_RAS_SIGNALING",-3.04138375,-0.025143321,0.006265924,0.002386918,-0.149283626,-2.675532005,"Down"]
[314,"WP_KISSPEPTINKISSPEPTIN_RECEPTOR_SYSTEM_IN_THE_OVARY",-3.043271453,-0.022687135,0.0062435,0.002372067,-0.182632995,-2.669840957,"Down"]
[313,"WP_MAMMARY_GLAND_DEVELOPMENT_PATHWAY_PUBERTY_STAGE_2_OF_4",-3.074924532,-0.040904206,0.005650447,0.002135332,-0.151192816,-2.573892358,"Down"]
[312,"BIOCARTA_G2_PATHWAY",-3.106946163,-0.031944172,0.005112007,0.001918079,-0.156778559,-2.475826414,"Down"]
[311,"REACTOME_GRB2_EVENTS_IN_ERBB2_SIGNALING",-3.108852596,-0.035582263,0.005083869,0.001905809,-0.093891234,-2.469956258,"Down"]
[310,"REACTOME_TRANSCRIPTIONAL_REGULATION_BY_E2F6",-3.117298912,-0.029111476,0.00495005,0.001852309,-0.211602998,-2.443906077,"Down"]
[309,"REACTOME_ABERRANT_REGULATION_OF_MITOTIC_EXIT_IN_CANCER_DUE_TO_RB1_DEFECTS",-3.121261136,-0.0327484,0.004893069,0.001827691,-0.222144066,-2.431661656,"Down"]
[308,"WP_IL10_ANTIINFLAMMATORY_SIGNALING_PATHWAY",-3.128810657,-0.043766356,0.004778333,0.001781615,-0.060964857,-2.408288828,"Down"]
[307,"REACTOME_PROCESSING_AND_ACTIVATION_OF_SUMO",-3.129865187,-0.051993557,0.004765607,0.001775265,-0.141525856,-2.405019625,"Down"]
[306,"WP_CELL_DIFFERENTIATION_EXPANDED_INDEX",-3.14116845,-0.046992426,0.004611381,0.001708494,-0.16809425,-2.3699093,"Down"]
[305,"REACTOME_SUMOYLATION_OF_TRANSCRIPTION_COFACTORS",-3.149228818,-0.030079046,0.004494314,0.0016623,-0.253971481,-2.344795577,"Down"]
[304,"REACTOME_TRIGLYCERIDE_CATABOLISM",-3.161046722,-0.03697176,0.004329178,0.001596649,-0.212375959,-2.307859339,"Down"]
[303,"PID_SYNDECAN_2_PATHWAY",-3.167051128,-0.040599407,0.004260693,0.001564216,-0.222274292,-2.289040432,"Down"]
[302,"WP_IL7_SIGNALING_PATHWAY",-3.17084419,-0.033205436,0.004213473,0.001544041,-0.186415095,-2.27713407,"Down"]
[301,"KEGG_CELL_CYCLE",-3.175770988,-0.020183804,0.004146753,0.001518195,-0.156298142,-2.261647876,"Down"]
[300,"REACTOME_TRANSPORT_OF_NUCLEOSIDES_AND_FREE_PURINE_AND_PYRIMIDINE_BASES_ACROSS_THE_PLASMA_MEMBRANE",-3.191111017,-0.044284969,0.00394475,0.001440252,-0.03200799,-2.213277868,"Down"]
[299,"REACTOME_RAF_INDEPENDENT_MAPK1_3_ACTIVATION",-3.192524109,-0.036055579,0.003929227,0.001433261,-0.187325959,-2.208810523,"Down"]
[298,"KEGG_CYSTEINE_AND_METHIONINE_METABOLISM",-3.197961041,-0.026483393,0.003863419,0.001406654,-0.153210746,-2.191603968,"Down"]
[297,"REACTOME_TP53_REGULATES_TRANSCRIPTION_OF_GENES_INVOLVED_IN_G1_CELL_CYCLE_ARREST",-3.23130878,-0.028981118,0.003461111,0.001253181,-0.025032576,-2.085432973,"Down"]
[296,"REACTOME_FORMATION_OF_SENESCENCE_ASSOCIATED_HETEROCHROMATIN_FOCI_SAHF",-3.233544292,-0.04031352,0.003437482,0.001243468,-0.287722774,-2.078276689,"Down"]
[295,"BIOCARTA_EFP_PATHWAY",-3.242683,-0.034749014,0.003348406,0.001204479,-0.184090701,-2.048971104,"Down"]
[294,"WP_IL9_SIGNALING_PATHWAY",-3.243156213,-0.043724585,0.003346013,0.001202491,-0.226525359,-2.047451399,"Down"]
[293,"REACTOME_EPHRIN_SIGNALING",-3.260517999,-0.039201037,0.003160669,0.001131624,-0.163773379,-1.99154307,"Down"]
[292,"REACTOME_PROLONGED_ERK_ACTIVATION_EVENTS",-3.26105625,-0.041322161,0.003157679,0.00112949,-0.261221676,-1.989805081,"Down"]
[291,"WP_CELL_CYCLE",-3.275371835,-0.02155262,0.003025569,0.001074082,-0.16032496,-1.943476533,"Down"]
[290,"BIOCARTA_P53_PATHWAY",-3.278030764,-0.039054277,0.00300307,0.001064072,-0.250431856,-1.934849526,"Down"]
[289,"WP_SEROTONIN_RECEPTOR_467_AND_NR3C_SIGNALING",-3.287510104,-0.040978151,0.002916096,0.001029084,-0.243005042,-1.904037086,"Down"]
[288,"WP_PHOTODYNAMIC_THERAPYINDUCED_HIF1_SURVIVAL_SIGNALING",-3.31898093,-0.040680791,0.002647998,0.000920422,-0.206755543,-1.801110911,"Down"]
[287,"REACTOME_ONCOGENIC_MAPK_SIGNALING",-3.327803698,-0.029555325,0.002568508,0.000891927,-0.156673622,-1.772081843,"Down"]
[286,"KEGG_GLYCOSPHINGOLIPID_BIOSYNTHESIS_LACTO_AND_NEOLACTO_SERIES",-3.337582032,-0.026475214,0.002497274,0.000861303,0.134425546,-1.739819735,"Down"]
[285,"PID_EPHRINB_REV_PATHWAY",-3.34137475,-0.032799146,0.002468424,0.00084969,-0.156603928,-1.727281066,"Down"]
[284,"BIOCARTA_EPHA4_PATHWAY",-3.342218619,-0.059288641,0.00246822,0.000847126,-0.039619294,-1.724489333,"Down"]
[283,"WP_T_CELL_RECEPTOR_AND_COSTIMULATORY_SIGNALING",-3.358690005,-0.038655417,0.002340304,0.000798494,-0.086253441,-1.669858293,"Down"]
[282,"PID_RHOA_REG_PATHWAY",-3.361887999,-0.024264788,0.002315813,0.000789358,-0.132092521,-1.65922066,"Down"]
[281,"WP_REGUCALCIN_IN_PROXIMAL_TUBULE_EPITHELIAL_KIDNEY_CELLS",-3.370301573,-0.031592096,0.002251099,0.000765783,-0.205645039,-1.631186426,"Down"]
[280,"BIOCARTA_REELIN_PATHWAY",-3.39915215,-0.05599463,0.002037889,0.000689821,0.011041563,-1.53452985,"Down"]
[279,"WP_GLUCURONIDATION",-3.409932866,-0.04530389,0.001965351,0.000663281,-0.144080856,-1.498202882,"Down"]
[278,"WP_TCELL_ANTIGEN_RECEPTOR_TCR_PATHWAY_DURING_STAPHYLOCOCCUS_AUREUS_INFECTION",-3.415516357,-0.025782848,0.001929589,0.000649912,-0.136393017,-1.479343944,"Down"]
[277,"REACTOME_GLUCURONIDATION",-3.41652729,-0.047586208,0.001924407,0.000647518,0.065067954,-1.475926132,"Down"]
[276,"KEGG_MATURITY_ONSET_DIABETES_OF_THE_YOUNG",-3.41674565,-0.029087949,0.001924407,0.000647003,0.370798776,-1.475187761,"Down"]
[275,"WP_RENINANGIOTENSINALDOSTERONE_SYSTEM_RAAS",-3.447578678,-0.028519756,0.001729545,0.000577874,-0.148896163,-1.370459491,"Down"]
[274,"REACTOME_GRB2_SOS_PROVIDES_LINKAGE_TO_MAPK_SIGNALING_FOR_INTEGRINS",-3.448616115,-0.058680341,0.001724694,0.000575673,-0.237119235,-1.366919548,"Down"]
[273,"BIOCARTA_INTEGRIN_PATHWAY",-3.460954271,-0.039303178,0.001649688,0.000550081,-0.198935878,-1.324738633,"Down"]
[272,"REACTOME_AURKA_ACTIVATION_BY_TPX2",-3.465794098,-0.028472778,0.001623741,0.000540335,-0.137385321,-1.308151918,"Down"]
[271,"REACTOME_PI3K_AKT_ACTIVATION",-3.47155698,-0.055221757,0.00159434,0.000528941,-0.264498834,-1.288371918,"Down"]
[270,"REACTOME_ACYL_CHAIN_REMODELLING_OF_PG",-3.490081294,-0.0345227,0.001497582,0.000493814,0.042816744,-1.22457094,"Down"]
[269,"REACTOME_INTERLEUKIN_21_SIGNALING",-3.547313493,-0.054712898,0.00122496,0.000398556,-0.046881152,-1.025335855,"Down"]
[268,"WP_OREXIN_RECEPTOR_PATHWAY",-3.549900664,-0.023042555,0.001214321,0.000394685,-0.112130335,-1.016253909,"Down"]
[267,"WP_AEROBIC_GLYCOLYSIS",-3.574351356,-0.078796697,0.001112757,0.0003598,-0.202195533,-0.930100124,"Down"]
[266,"KEGG_NITROGEN_METABOLISM",-3.574724978,-0.027499832,0.001112338,0.00035929,0.140721073,-0.928779113,"Down"]
[265,"PID_ANGIOPOIETIN_RECEPTOR_PATHWAY",-3.597427053,-0.030361564,0.00102559,0.000329543,-0.174986623,-0.848256067,"Down"]
[264,"REACTOME_G1_S_SPECIFIC_TRANSCRIPTION",-3.620242057,-0.028575332,0.000944773,0.000301984,0.0225001,-0.766825855,"Down"]
[263,"WP_TGFBETA_SIGNALING_IN_THYROID_CELLS_FOR_EPITHELIALMESENCHYMAL_TRANSITION",-3.626332414,-0.051083614,0.0009239,0.000295001,-0.295698403,-0.74500258,"Down"]
[262,"KEGG_LONG_TERM_DEPRESSION",-3.631105974,-0.026798688,0.000909621,0.000289634,-0.140941236,-0.727872429,"Down"]
[261,"KEGG_TYROSINE_METABOLISM",-3.640923052,-0.027670146,0.000877122,0.000278883,0.103895854,-0.692573518,"Down"]
[260,"REACTOME_TRAFFICKING_OF_AMPA_RECEPTORS",-3.643779298,-0.031432804,0.000869349,0.000275826,-0.154187313,-0.682285767,"Down"]
[259,"REACTOME_CA2_PATHWAY",-3.662464036,-0.028908101,0.000812171,0.00025659,-0.10082092,-0.61479003,"Down"]
[258,"REACTOME_LECTIN_PATHWAY_OF_COMPLEMENT_ACTIVATION",-3.667515942,-0.0537135,0.000797257,0.00025161,0.036291456,-0.596482336,"Down"]
[257,"REACTOME_SIGNALING_BY_BRAF_AND_RAF1_FUSIONS",-3.6692728,-0.035758127,0.000792683,0.000249899,-0.146869828,-0.590109796,"Down"]
[256,"REACTOME_MECP2_REGULATES_NEURONAL_RECEPTORS_AND_CHANNELS",-3.674239316,-0.036110155,0.000778362,0.000245122,-0.153693102,-0.572078792,"Down"]
[255,"PID_VEGF_VEGFR_PATHWAY",-3.688522016,-0.051534004,0.000740998,0.000231858,-0.100745647,-0.520091246,"Down"]
[254,"REACTOME_DOPAMINE_NEUROTRANSMITTER_RELEASE_CYCLE",-3.691956174,-0.037419739,0.00073192,0.000228771,-0.082753904,-0.507561618,"Down"]
[253,"PID_RHODOPSIN_PATHWAY",-3.694732424,-0.023246555,0.000724806,0.000226304,0.443424369,-0.497423981,"Down"]
[252,"REACTOME_BIOSYNTHESIS_OF_EPA_DERIVED_SPMS",-3.709111795,-0.065899616,0.000686621,0.000213919,-0.058527379,-0.444796685,"Down"]
[251,"REACTOME_SUMO_IS_PROTEOLYTICALLY_PROCESSED",-3.725620829,-0.073082967,0.000645599,0.000200486,-0.13076712,-0.384126546,"Down"]
[250,"PID_IL2_STAT5_PATHWAY",-3.732887942,-0.034903799,0.000628743,0.000194828,-0.178588062,-0.357335983,"Down"]
[249,"KEGG_CHRONIC_MYELOID_LEUKEMIA",-3.735442714,-0.026740381,0.000623117,0.000192874,-0.256611717,-0.34790547,"Down"]
[248,"WP_BLADDER_CANCER",-3.736624112,-0.033238202,0.000621572,0.000191977,-0.2098692,-0.343542388,"Down"]
[247,"WP_FOLATE_METABOLISM",-3.74709944,-0.022986939,0.000597674,0.000184194,-0.013092422,-0.304795936,"Down"]
[246,"SA_G1_AND_S_PHASES",-3.761288259,-0.050485215,0.000569355,0.000174124,-0.265578258,-0.252143482,"Down"]
[245,"PID_IL12_STAT4_PATHWAY",-3.766442888,-0.036435272,0.000559049,0.000170596,0.015117727,-0.232966925,"Down"]
[244,"REACTOME_PI3K_EVENTS_IN_ERBB2_SIGNALING",-3.766725848,-0.04510485,0.000559038,0.000170404,-0.040648933,-0.231913489,"Down"]
[243,"WP_MIRNA_BIOGENESIS",-3.788042566,-0.067946327,0.000516375,0.00015653,-0.199724902,-0.152329155,"Down"]
[242,"WP_MAPK_AND_NFKB_SIGNALING_PATHWAYS_INHIBITED_BY_YERSINIA_YOPJ",-3.789363698,-0.052063761,0.000514228,0.000155706,-0.182274711,-0.147382251,"Down"]
[241,"WP_GABA_RECEPTOR_SIGNALING",-3.811042025,-0.036174217,0.000473043,0.000142757,-0.030825403,-0.065966305,"Down"]
[240,"WP_PURINE_METABOLISM",-3.831857608,-0.051815966,0.000436978,0.000131285,-0.182075466,0.012639935,"Down"]
[239,"BIOCARTA_NUCLEARRS_PATHWAY",-3.847841485,-0.035537208,0.000411949,0.000123071,0.028987447,0.073286293,"Down"]
[238,"PID_VEGFR1_PATHWAY",-3.849327524,-0.041578073,0.00040994,0.000122333,-0.211312454,0.07893728,"Down"]
[237,"REACTOME_ASSEMBLY_AND_CELL_SURFACE_PRESENTATION_OF_NMDA_RECEPTORS",-3.856154981,-0.031208143,0.000401012,0.000118994,-0.063626568,0.104927787,"Down"]
[236,"KEGG_TYPE_II_DIABETES_MELLITUS",-3.857742155,-0.028704965,0.000398891,0.00011823,-0.154510072,0.110976278,"Down"]
[235,"REACTOME_NUCLEOTIDE_LIKE_PURINERGIC_RECEPTORS",-3.860887509,-0.028795317,0.000394278,0.00011673,0.392491367,0.122970006,"Down"]
[234,"WP_OVERVIEW_OF_NANOPARTICLE_EFFECTS",-3.864329022,-0.049967701,0.000389246,0.000115109,-0.161629544,0.136104059,"Down"]
[233,"REACTOME_GLUCOSE_METABOLISM",-3.865407373,-0.02923941,0.000387985,0.000114605,-0.209230327,0.140221808,"Down"]
[232,"REACTOME_FGFRL1_MODULATION_OF_FGFR1_SIGNALING",-3.880926177,-0.046773105,0.000365472,0.000107586,0.06289057,0.199606518,"Down"]
[231,"REACTOME_REGULATION_OF_GENE_EXPRESSION_IN_EARLY_PANCREATIC_PRECURSOR_CELLS",-3.886341187,-0.020475926,0.000358301,0.000105234,0.377638418,0.220382877,"Down"]
[230,"REACTOME_POLO_LIKE_KINASE_MEDIATED_EVENTS",-3.900353209,-0.034974633,0.000339897,{"v":9.94e-05,"d":"9.94E-05"},0.11899103,0.274276662,"Down"]
[229,"WP_OSTEOPONTIN_SIGNALING",-3.930996979,-0.044751182,0.000301741,{"v":8.76e-05,"d":"8.76E-05"},-0.211820863,0.392805516,"Down"]
[228,"PID_CXCR3_PATHWAY",-3.931722736,-0.034758012,0.000301188,{"v":8.73e-05,"d":"8.73E-05"},-0.185966532,0.395623779,"Down"]
[227,"BIOCARTA_41BB_PATHWAY",-3.951006946,-0.044458451,0.000280482,{"v":8.06e-05,"d":"8.06E-05"},-0.142323245,0.470695798,"Down"]
[226,"WP_MET_IN_TYPE_1_PAPILLARY_RENAL_CELL_CARCINOMA",-3.951925484,-0.034877477,0.000279968,{"v":8.03e-05,"d":"8.03E-05"},-0.205195319,0.474280613,"Down"]
[225,"REACTOME_SIGNALING_BY_MODERATE_KINASE_ACTIVITY_BRAF_MUTANTS",-3.968147184,-0.045451817,0.000262035,{"v":7.51e-05,"d":"7.51E-05"},-0.137807112,0.537724791,"Down"]
[224,"REACTOME_RECEPTOR_TYPE_TYROSINE_PROTEIN_PHOSPHATASES",-3.989463177,-0.045858851,0.000240593,{"v":6.87e-05,"d":"6.87E-05"},-0.091006289,0.621481721,"Down"]
[223,"REACTOME_CONVERSION_FROM_APC_C_CDC20_TO_APC_C_CDH1_IN_LATE_ANAPHASE",-4.028826517,-0.043097569,0.000205882,{"v":5.82e-05,"d":"5.82E-05"},-0.204899052,0.777311807,"Down"]
[222,"REACTOME_N_GLYCAN_ANTENNAE_ELONGATION",-4.032673097,-0.043977588,0.000202809,{"v":5.73e-05,"d":"5.73E-05"},-0.075774791,0.792620178,"Down"]
[221,"REACTOME_SCAVENGING_BY_CLASS_F_RECEPTORS",-4.039512322,-0.076883956,0.000198453,{"v":5.57e-05,"d":"5.57E-05"},-0.145612826,0.819873958,"Down"]
[220,"WP_THYROXINE_THYROID_HORMONE_PRODUCTION",-4.041333801,-0.019374305,0.000197405,{"v":5.53e-05,"d":"5.53E-05"},0.551013288,0.827140062,"Down"]
[219,"REACTOME_PEPTIDE_HORMONE_BIOSYNTHESIS",-4.047798381,-0.058136721,0.000192541,{"v":5.38e-05,"d":"5.38E-05"},-0.00266956,0.852954072,"Down"]
[218,"WP_STEROL_REGULATORY_ELEMENTBINDING_PROTEINS_SREBP_SIGNALING",-4.057937261,-0.026996342,0.00018556,{"v":5.15e-05,"d":"5.15E-05"},-0.242655551,0.893521772,"Down"]
[217,"BIOCARTA_CYTOKINE_PATHWAY",-4.068031179,-0.03653902,0.000178202,{"v":4.93e-05,"d":"4.93E-05"},0.19685636,0.934008651,"Down"]
[216,"REACTOME_P130CAS_LINKAGE_TO_MAPK_SIGNALING_FOR_INTEGRINS",-4.07928658,-0.068721643,0.000170484,{"v":4.7e-05,"d":"4.70E-05"},-0.178595994,0.979270827,"Down"]
[215,"REACTOME_ACTIVATION_OF_THE_PHOTOTRANSDUCTION_CASCADE",-4.084063231,-0.039618328,0.000167373,{"v":4.61e-05,"d":"4.61E-05"},0.490139616,0.998516668,"Down"]
[214,"REACTOME_NETRIN_MEDIATED_REPULSION_SIGNALS",-4.090897342,-0.051338419,0.000163035,{"v":4.48e-05,"d":"4.48E-05"},0.072019003,1.026090807,"Down"]
[213,"REACTOME_GRB7_EVENTS_IN_ERBB2_SIGNALING",-4.106117232,-0.063818742,0.000153882,{"v":4.19e-05,"d":"4.19E-05"},-0.096973061,1.087662493,"Down"]
[212,"REACTOME_TRIGLYCERIDE_METABOLISM",-4.11007509,-0.037508821,0.000151666,{"v":4.12e-05,"d":"4.12E-05"},-0.168243355,1.103710713,"Down"]
[211,"REACTOME_ASSEMBLY_OF_THE_ORC_COMPLEX_AT_THE_ORIGIN_OF_REPLICATION",-4.113859347,-0.059840676,0.000149406,{"v":4.06e-05,"d":"4.06E-05"},-0.120882197,1.119069223,"Down"]
[210,"WP_SPLICING_FACTOR_NOVA_REGULATED_SYNAPTIC_PROTEINS",-4.126539644,-0.034531184,0.00014165,{"v":3.84e-05,"d":"3.84E-05"},-0.131909898,1.170633773,"Down"]
[209,"REACTOME_CELL_EXTRACELLULAR_MATRIX_INTERACTIONS",-4.158957549,-0.066041016,0.000124364,{"v":3.34e-05,"d":"3.34E-05"},-0.172460815,1.303170084,"Down"]
[208,"BIOCARTA_CIRCADIAN_PATHWAY",-4.22356494,-0.063983577,{"v":9.57e-05,"d":"9.57E-05"},{"v":2.52e-05,"d":"2.52E-05"},-0.307921374,1.570345638,"Down"]
[207,"REACTOME_SEROTONIN_NEUROTRANSMITTER_RELEASE_CYCLE",-4.228510272,-0.047820249,{"v":9.38e-05,"d":"9.38E-05"},{"v":2.46e-05,"d":"2.46E-05"},-0.01881218,1.590962981,"Down"]
[206,"REACTOME_BASIGIN_INTERACTIONS",-4.230686821,-0.050761673,{"v":9.31e-05,"d":"9.31E-05"},{"v":2.44e-05,"d":"2.44E-05"},-0.142060674,1.600044628,"Down"]
[205,"REACTOME_SENSORY_PROCESSING_OF_SOUND",-4.235805362,-0.035845252,{"v":9.14e-05,"d":"9.14E-05"},{"v":2.39e-05,"d":"2.39E-05"},-0.059288455,1.621419807,"Down"]
[204,"WP_PHOTODYNAMIC_THERAPYINDUCED_UNFOLDED_PROTEIN_RESPONSE",-4.25867207,-0.052104061,{"v":8.28e-05,"d":"8.28E-05"},{"v":2.16e-05,"d":"2.16E-05"},-0.187166344,1.717221582,"Down"]
[203,"REACTOME_PHOSPHORYLATION_OF_THE_APC_C",-4.267095974,-0.045834177,{"v":7.99e-05,"d":"7.99E-05"},{"v":2.08e-05,"d":"2.08E-05"},-0.214324182,1.752641706,"Down"]
[202,"PID_S1P_S1P4_PATHWAY",-4.268069775,-0.061221866,{"v":7.96e-05,"d":"7.96E-05"},{"v":2.07e-05,"d":"2.07E-05"},-0.182564299,1.756740692,"Down"]
[201,"REACTOME_ROS_AND_RNS_PRODUCTION_IN_PHAGOCYTES",-4.26878999,-0.03846096,{"v":7.95e-05,"d":"7.95E-05"},{"v":2.06e-05,"d":"2.06E-05"},-0.008542165,1.759772855,"Down"]
[200,"BIOCARTA_MPR_PATHWAY",-4.280894474,-0.043523596,{"v":7.55e-05,"d":"7.55E-05"},{"v":1.95e-05,"d":"1.95E-05"},-0.124411515,1.810808838,"Down"]
[199,"BIOCARTA_BARR_MAPK_PATHWAY",-4.290322294,-0.056906022,{"v":7.26e-05,"d":"7.26E-05"},{"v":1.87e-05,"d":"1.87E-05"},-0.196806133,1.850657436,"Down"]
[198,"REACTOME_SENSORY_PERCEPTION",-4.311847116,-0.019124528,{"v":6.63e-05,"d":"6.63E-05"},{"v":1.7e-05,"d":"1.70E-05"},0.024983674,1.941958704,"Down"]
[197,"BIOCARTA_FREE_PATHWAY",-4.345051785,-0.055711509,{"v":5.73e-05,"d":"5.73E-05"},{"v":1.47e-05,"d":"1.47E-05"},-0.1179258,2.08368073,"Down"]
[196,"REACTOME_SIGNALING_BY_MAPK_MUTANTS",-4.385713486,-0.075319106,{"v":4.79e-05,"d":"4.79E-05"},{"v":1.22e-05,"d":"1.22E-05"},-0.228967865,2.258681979,"Down"]
[195,"WP_PURINE_METABOLISM_AND_RELATED_DISORDERS",-4.391467599,-0.044016185,{"v":4.68e-05,"d":"4.68E-05"},{"v":1.19e-05,"d":"1.19E-05"},-0.184735518,2.283575765,"Down"]
[194,"REACTOME_INHIBITION_OF_THE_PROTEOLYTIC_ACTIVITY_OF_APC_C_REQUIRED_FOR_THE_ONSET_OF_ANAPHASE_BY_MITOTIC_SPINDLE_CHECKPOINT_COMPONENTS",-4.396020601,-0.043273805,{"v":4.59e-05,"d":"4.59E-05"},{"v":1.16e-05,"d":"1.16E-05"},-0.195301807,2.303295902,"Down"]
[193,"REACTOME_TIE2_SIGNALING",-4.397902893,-0.050371644,{"v":4.55e-05,"d":"4.55E-05"},{"v":1.15e-05,"d":"1.15E-05"},-0.166821184,2.311454404,"Down"]
[192,"WP_DISRUPTION_OF_POSTSYNAPTIC_SIGNALING_BY_CNV",-4.410475291,-0.035380485,{"v":4.32e-05,"d":"4.32E-05"},{"v":1.09e-05,"d":"1.09E-05"},-0.080471351,2.366035292,"Down"]
[191,"BIOCARTA_BARRESTIN_PATHWAY",-4.424689324,-0.06123395,{"v":4.07e-05,"d":"4.07E-05"},{"v":1.02e-05,"d":"1.02E-05"},-0.151435783,2.427926909,"Down"]
[190,"REACTOME_INTERLEUKIN_2_SIGNALING",-4.436261829,-0.058760184,{"v":3.89e-05,"d":"3.89E-05"},{"v":9.67e-06,"d":"9.67E-06"},-0.035774276,2.478460688,"Down"]
[189,"BIOCARTA_STAT3_PATHWAY",-4.439444751,-0.076983304,{"v":3.84e-05,"d":"3.84E-05"},{"v":9.53e-06,"d":"9.53E-06"},-0.171402684,2.492382262,"Down"]
[188,"WP_CANCER_IMMUNOTHERAPY_BY_PD1_BLOCKADE",-4.480604705,-0.043075751,{"v":3.21e-05,"d":"3.21E-05"},{"v":7.88e-06,"d":"7.88E-06"},0.043029779,2.673289869,"Down"]
[187,"REACTOME_PYRIMIDINE_SALVAGE",-4.483514128,-0.057662779,{"v":3.18e-05,"d":"3.18E-05"},{"v":7.78e-06,"d":"7.78E-06"},-0.119410035,2.686139324,"Down"]
[186,"REACTOME_ABERRANT_REGULATION_OF_MITOTIC_G1_S_TRANSITION_IN_CANCER_DUE_TO_RB1_DEFECTS",-4.490162993,-0.050739,{"v":3.09e-05,"d":"3.09E-05"},{"v":7.54e-06,"d":"7.54E-06"},-0.237916493,2.715534674,"Down"]
[185,"WP_PLURIPOTENT_STEM_CELL_DIFFERENTIATION_PATHWAY",-4.500242757,-0.034887098,{"v":2.95e-05,"d":"2.95E-05"},{"v":7.2e-06,"d":"7.20E-06"},-0.014936236,2.760179721,"Down"]
[184,"WP_MAMMARY_GLAND_DEVELOPMENT_PATHWAY_PREGNANCY_AND_LACTATION_STAGE_3_OF_4",-4.524303053,-0.040805192,{"v":2.65e-05,"d":"2.65E-05"},{"v":6.43e-06,"d":"6.43E-06"},-0.095825787,2.867143136,"Down"]
[183,"WP_AMINO_ACID_METABOLISM",-4.556237601,-0.026625314,{"v":2.29e-05,"d":"2.29E-05"},{"v":5.54e-06,"d":"5.54E-06"},-0.115998844,3.009974699,"Down"]
[182,"REACTOME_LGI_ADAM_INTERACTIONS",-4.586065104,-0.037398075,{"v":2.01e-05,"d":"2.01E-05"},{"v":4.81e-06,"d":"4.81E-06"},0.180647893,3.144269967,"Down"]
[181,"KEGG_ALPHA_LINOLENIC_ACID_METABOLISM",-4.604734666,-0.043021729,{"v":1.85e-05,"d":"1.85E-05"},{"v":4.4e-06,"d":"4.40E-06"},0.1782229,3.228763901,"Down"]
[180,"REACTOME_VITAMIN_D_CALCIFEROL_METABOLISM",-4.621603183,-0.079912416,{"v":1.71e-05,"d":"1.71E-05"},{"v":4.06e-06,"d":"4.06E-06"},0.025027382,3.305395422,"Down"]
[179,"REACTOME_MUSCLE_CONTRACTION",-4.628276474,-0.02469691,{"v":1.66e-05,"d":"1.66E-05"},{"v":3.93e-06,"d":"3.93E-06"},-0.021052094,3.335786966,"Down"]
[178,"PID_S1P_S1P1_PATHWAY",-4.628280402,-0.062359584,{"v":1.66e-05,"d":"1.66E-05"},{"v":3.93e-06,"d":"3.93E-06"},-0.175214618,3.335804871,"Down"]
[177,"WP_HIPPOYAP_SIGNALING_PATHWAY",-4.663272665,-0.048732222,{"v":1.42e-05,"d":"1.42E-05"},{"v":3.33e-06,"d":"3.33E-06"},-0.164920679,3.49586876,"Down"]
[176,"REACTOME_G_ALPHA_I_SIGNALLING_EVENTS",-4.689821913,-0.014440345,{"v":1.26e-05,"d":"1.26E-05"},{"v":2.93e-06,"d":"2.93E-06"},0.07393278,3.618098225,"Down"]
[175,"REACTOME_G2_M_DNA_REPLICATION_CHECKPOINT",-4.727853593,-0.049595264,{"v":1.06e-05,"d":"1.06E-05"},{"v":2.43e-06,"d":"2.43E-06"},0.066564134,3.794372607,"Down"]
[174,"BIOCARTA_NEUTROPHIL_PATHWAY",-4.759307229,-0.05149832,{"v":9.14e-06,"d":"9.14E-06"},{"v":2.09e-06,"d":"2.09E-06"},0.269488121,3.941208783,"Down"]
[173,"REACTOME_EGFR_INTERACTS_WITH_PHOSPHOLIPASE_C_GAMMA",-4.780528032,-0.057014731,{"v":8.3e-06,"d":"8.30E-06"},{"v":1.88e-06,"d":"1.88E-06"},0.103930298,4.040811726,"Down"]
[172,"WP_GLYCOLYSIS_AND_GLUCONEOGENESIS",-4.814086155,-0.060775672,{"v":7.08e-06,"d":"7.08E-06"},{"v":1.59e-06,"d":"1.59E-06"},-0.162228439,4.199204574,"Down"]
[171,"WP_PROXIMAL_TUBULE_TRANSPORT",-4.833438461,-0.041175741,{"v":6.5e-06,"d":"6.50E-06"},{"v":1.45e-06,"d":"1.45E-06"},-0.071926803,4.291038188,"Down"]
[170,"REACTOME_HEME_DEGRADATION",-4.839776471,-0.068521502,{"v":6.32e-06,"d":"6.32E-06"},{"v":1.4e-06,"d":"1.40E-06"},-0.074947717,4.321192466,"Down"]
[169,"WP_TCELL_RECEPTOR_TCR_SIGNALING_PATHWAY",-4.865098511,-0.031350711,{"v":5.58e-06,"d":"5.58E-06"},{"v":1.24e-06,"d":"1.24E-06"},-0.144502561,4.442051508,"Down"]
[168,"WP_STRIATED_MUSCLE_CONTRACTION_PATHWAY",-4.93507953,-0.060236226,{"v":4.01e-06,"d":"4.01E-06"},{"v":8.71e-07,"d":"8.71E-07"},-0.046512762,4.779261015,"Down"]
[167,"PID_HNF3B_PATHWAY",-4.968910086,-0.048839887,{"v":3.41e-06,"d":"3.41E-06"},{"v":7.33e-07,"d":"7.33E-07"},-0.104672491,4.943959611,"Down"]
[166,"WP_MIRNAS_INVOLVED_IN_DNA_DAMAGE_RESPONSE",-4.998345974,-0.054548108,{"v":2.96e-06,"d":"2.96E-06"},{"v":6.31e-07,"d":"6.31E-07"},-0.211264299,5.088155405,"Down"]
[165,"BIOCARTA_IL10_PATHWAY",-5.001320611,-0.062140196,{"v":2.92e-06,"d":"2.92E-06"},{"v":6.21e-07,"d":"6.21E-07"},-0.006450306,5.102773239,"Down"]
[164,"REACTOME_ERYTHROCYTES_TAKE_UP_OXYGEN_AND_RELEASE_CARBON_DIOXIDE",-5.03063566,-0.064609125,{"v":2.53e-06,"d":"2.53E-06"},{"v":5.35e-07,"d":"5.35E-07"},0.343760069,5.247285015,"Down"]
[163,"PID_E2F_PATHWAY",-5.036168783,-0.029748075,{"v":2.46e-06,"d":"2.46E-06"},{"v":5.2e-07,"d":"5.20E-07"},-0.157534982,5.274653427,"Down"]
[162,"BIOCARTA_BARRESTIN_SRC_PATHWAY",-5.050060973,-0.061646955,{"v":2.3e-06,"d":"2.30E-06"},{"v":4.84e-07,"d":"4.84E-07"},-0.196045387,5.343497276,"Down"]
[161,"BIOCARTA_G1_PATHWAY",-5.052864153,-0.042279293,{"v":2.27e-06,"d":"2.27E-06"},{"v":4.77e-07,"d":"4.77E-07"},-0.228294797,5.357411045,"Down"]
[160,"REACTOME_ALK_MUTANTS_BIND_TKIS",-5.071512066,-0.082312071,{"v":2.08e-06,"d":"2.08E-06"},{"v":4.33e-07,"d":"4.33E-07"},-0.096202736,5.450162489,"Down"]
[159,"REACTOME_INTERACTION_WITH_CUMULUS_CELLS_AND_THE_ZONA_PELLUCIDA",-5.075572547,-0.079217192,{"v":2.04e-06,"d":"2.04E-06"},{"v":4.24e-07,"d":"4.24E-07"},0.132256182,5.470402699,"Down"]
[158,"KEGG_FRUCTOSE_AND_MANNOSE_METABOLISM",-5.083302819,-0.048906169,{"v":1.96e-06,"d":"1.96E-06"},{"v":4.07e-07,"d":"4.07E-07"},-0.18810462,5.508979236,"Down"]
[157,"REACTOME_DISEASES_OF_MITOTIC_CELL_CYCLE",-5.093714799,-0.045392889,{"v":1.86e-06,"d":"1.86E-06"},{"v":3.86e-07,"d":"3.86E-07"},-0.193144871,5.561028658,"Down"]
[156,"KEGG_BLADDER_CANCER",-5.100359085,-0.043073434,{"v":1.8e-06,"d":"1.80E-06"},{"v":3.73e-07,"d":"3.73E-07"},-0.207194994,5.594297569,"Down"]
[155,"WP_NITRIC_OXIDE_METABOLISM_IN_CYSTIC_FIBROSIS",-5.100971964,-0.05662276,{"v":1.8e-06,"d":"1.80E-06"},{"v":3.71e-07,"d":"3.71E-07"},0.051706613,5.597368474,"Down"]
[154,"WP_PURINERGIC_SIGNALING",-5.111278919,-0.040666602,{"v":1.72e-06,"d":"1.72E-06"},{"v":3.52e-07,"d":"3.52E-07"},0.124688895,5.649066444,"Down"]
[153,"REACTOME_ION_TRANSPORT_BY_P_TYPE_ATPASES",-5.111423436,-0.030795929,{"v":1.72e-06,"d":"1.72E-06"},{"v":3.52e-07,"d":"3.52E-07"},-0.086262113,5.649792036,"Down"]
[152,"REACTOME_RETROGRADE_TRANSPORT_AT_THE_TRANS_GOLGI_NETWORK",-5.123225349,-0.040222845,{"v":1.62e-06,"d":"1.62E-06"},{"v":3.31e-07,"d":"3.31E-07"},-0.251082302,5.70911478,"Down"]
[151,"WP_CORI_CYCLE",-5.131238217,-0.087227883,{"v":1.56e-06,"d":"1.56E-06"},{"v":3.17e-07,"d":"3.17E-07"},-0.170126206,5.749467605,"Down"]
[150,"REACTOME_VLDL_ASSEMBLY",-5.138948217,-0.144520905,{"v":1.5e-06,"d":"1.50E-06"},{"v":3.04e-07,"d":"3.04E-07"},0.122602963,5.788353096,"Down"]
[149,"REACTOME_SYNTHESIS_OF_UDP_N_ACETYL_GLUCOSAMINE",-5.154920176,-0.072679018,{"v":1.38e-06,"d":"1.38E-06"},{"v":2.8e-07,"d":"2.80E-07"},-0.310768287,5.869088552,"Down"]
[148,"REACTOME_HISTIDINE_CATABOLISM",-5.160473692,-0.066435221,{"v":1.34e-06,"d":"1.34E-06"},{"v":2.72e-07,"d":"2.72E-07"},0.23489364,5.897217684,"Down"]
[147,"REACTOME_PRESYNAPTIC_FUNCTION_OF_KAINATE_RECEPTORS",-5.193461491,-0.058292635,{"v":1.14e-06,"d":"1.14E-06"},{"v":2.28e-07,"d":"2.28E-07"},0.009185639,6.064911272,"Down"]
[146,"REACTOME_SENSORY_PROCESSING_OF_SOUND_BY_OUTER_HAIR_CELLS_OF_THE_COCHLEA",-5.218397117,-0.04677063,{"v":1e-06,"d":"1.00E-06"},{"v":2e-07,"d":"2.00E-07"},-0.020953673,6.192360908,"Down"]
[145,"WP_FATTY_ACID_OMEGAOXIDATION",-5.316299707,-0.056938596,{"v":6.05e-07,"d":"6.05E-07"},{"v":1.18e-07,"d":"1.18E-07"},0.268287997,6.698489797,"Down"]
[144,"REACTOME_NEGATIVE_REGULATION_OF_NMDA_RECEPTOR_MEDIATED_NEURONAL_TRANSMISSION",-5.363846689,-0.039186367,{"v":4.75e-07,"d":"4.75E-07"},{"v":9.13e-08,"d":"9.13E-08"},0.073484499,6.947588834,"Down"]
[143,"REACTOME_VITAMINS",-5.401105818,-0.118690876,{"v":3.89e-07,"d":"3.89E-07"},{"v":7.45e-08,"d":"7.45E-08"},0.127759597,7.144293456,"Down"]
[142,"KEGG_GLYCOLYSIS_GLUCONEOGENESIS",-5.429814832,-0.055374656,{"v":3.36e-07,"d":"3.36E-07"},{"v":6.36e-08,"d":"6.36E-08"},-0.114684242,7.296759599,"Down"]
[141,"WP_NOCGMPPKG_MEDIATED_NEUROPROTECTION",-5.443827502,-0.03741894,{"v":3.13e-07,"d":"3.13E-07"},{"v":5.89e-08,"d":"5.89E-08"},-0.000235124,7.371461845,"Down"]
[140,"REACTOME_SENSORY_PERCEPTION_OF_TASTE",-5.508415255,-0.038421337,{"v":2.24e-07,"d":"2.24E-07"},{"v":4.11e-08,"d":"4.11E-08"},0.283803102,7.718194227,"Down"]
[139,"REACTOME_ERYTHROCYTES_TAKE_UP_CARBON_DIOXIDE_AND_RELEASE_OXYGEN",-5.533433698,-0.064349509,{"v":1.96e-07,"d":"1.96E-07"},{"v":3.57e-08,"d":"3.57E-08"},0.165691419,7.853567455,"Down"]
[138,"REACTOME_MRNA_EDITING_C_TO_U_CONVERSION",-5.613294776,-0.057881784,{"v":1.27e-07,"d":"1.27E-07"},{"v":2.28e-08,"d":"2.28E-08"},0.345550196,8.289663737,"Down"]
[137,"REACTOME_REGULATION_OF_GENE_EXPRESSION_IN_BETA_CELLS",-5.624726046,-0.064282328,{"v":1.2e-07,"d":"1.20E-07"},{"v":2.13e-08,"d":"2.13E-08"},0.043844815,8.352580989,"Down"]
[136,"REACTOME_ATTACHMENT_AND_ENTRY",-5.634337338,-0.116575567,{"v":1.14e-07,"d":"1.14E-07"},{"v":2.02e-08,"d":"2.02E-08"},-0.092072573,8.405576975,"Down"]
[135,"REACTOME_LIPID_PARTICLE_ORGANIZATION",-5.696173866,-0.040625995,{"v":8.18e-08,"d":"8.18E-08"},{"v":1.42e-08,"d":"1.42E-08"},0.467039418,8.748631203,"Down"]
[134,"WP_MECHANOREGULATION_AND_PATHOLOGY_OF_YAPTAZ_VIA_HIPPO_AND_NONHIPPO_MECHANISMS",-5.715353215,-0.053778895,{"v":7.33e-08,"d":"7.33E-08"},{"v":1.27e-08,"d":"1.27E-08"},-0.090074672,8.855768989,"Down"]
[133,"BIOCARTA_NO2IL12_PATHWAY",-5.71912202,-0.037095496,{"v":7.19e-08,"d":"7.19E-08"},{"v":1.24e-08,"d":"1.24E-08"},0.449588872,8.876862825,"Down"]
[132,"WP_SEROTONIN_HTR1_GROUP_AND_FOS_PATHWAY",-5.724621466,-0.059269578,{"v":7.01e-08,"d":"7.01E-08"},{"v":1.2e-08,"d":"1.20E-08"},-0.217721582,8.907667085,"Down"]
[131,"REACTOME_BIOSYNTHESIS_OF_SPECIALIZED_PRORESOLVING_MEDIATORS_SPMS",-5.745640145,-0.051049267,{"v":6.24e-08,"d":"6.24E-08"},{"v":1.06e-08,"d":"1.06E-08"},0.180363494,9.025663395,"Down"]
[130,"REACTOME_ACYL_CHAIN_REMODELLING_OF_PS",-5.771856674,-0.054225666,{"v":5.38e-08,"d":"5.38E-08"},{"v":9.13e-09,"d":"9.13E-09"},0.089345798,9.173425162,"Down"]
[129,"SA_REG_CASCADE_OF_CYCLIN_EXPR",-5.804139058,-0.065917423,{"v":4.48e-08,"d":"4.48E-08"},{"v":7.56e-09,"d":"7.56E-09"},-0.058363467,9.356267604,"Down"]
[128,"REACTOME_ACETYLCHOLINE_NEUROTRANSMITTER_RELEASE_CYCLE",-5.826896626,-0.076914647,{"v":3.95e-08,"d":"3.95E-08"},{"v":6.61e-09,"d":"6.61E-09"},-0.077299774,9.485754474,"Down"]
[127,"BIOCARTA_RB_PATHWAY",-5.829352947,-0.067823852,{"v":3.9e-08,"d":"3.90E-08"},{"v":6.52e-09,"d":"6.52E-09"},-0.156086074,9.499759776,"Down"]
[126,"REACTOME_STRIATED_MUSCLE_CONTRACTION",-5.839561283,-0.063356189,{"v":3.69e-08,"d":"3.69E-08"},{"v":6.14e-09,"d":"6.14E-09"},0.015721638,9.558026079,"Down"]
[125,"BIOCARTA_MITR_PATHWAY",-5.846849896,-0.107660835,{"v":3.55e-08,"d":"3.55E-08"},{"v":5.88e-09,"d":"5.88E-09"},-0.127897183,9.599687612,"Down"]
[124,"PID_CD8_TCR_DOWNSTREAM_PATHWAY",-5.848002795,-0.049769337,{"v":3.53e-08,"d":"3.53E-08"},{"v":5.84e-09,"d":"5.84E-09"},-0.036529478,9.606282146,"Down"]
[123,"WP_BENZENE_METABOLISM",-5.872117919,-0.138912338,{"v":3.08e-08,"d":"3.08E-08"},{"v":5.06e-09,"d":"5.06E-09"},0.045064151,9.744507121,"Down"]
[122,"REACTOME_DEFECTIVE_C1GALT1C1_CAUSES_TNPS",-5.877759591,-0.060231913,{"v":2.98e-08,"d":"2.98E-08"},{"v":4.89e-09,"d":"4.89E-09"},0.092264789,9.776923687,"Down"]
[121,"REACTOME_RUNX1_AND_FOXP3_CONTROL_THE_DEVELOPMENT_OF_REGULATORY_T_LYMPHOCYTES_TREGS",-5.928925677,-0.079859035,{"v":2.21e-08,"d":"2.21E-08"},{"v":3.61e-09,"d":"3.61E-09"},0.119801305,10.07228997,"Down"]
[120,"BIOCARTA_SRCRPTP_PATHWAY",-5.941777478,-0.079777517,{"v":2.05e-08,"d":"2.05E-08"},{"v":3.34e-09,"d":"3.34E-09"},-0.080774461,10.14686723,"Down"]
[119,"BIOCARTA_ION_PATHWAY",-5.972317825,-0.07174655,{"v":1.73e-08,"d":"1.73E-08"},{"v":2.78e-09,"d":"2.78E-09"},0.028176127,10.32471286,"Down"]
[118,"WP_SARSCOV2_ALTERING_ANGIOGENESIS_VIA_NRP1",-5.993240002,-0.122063794,{"v":1.54e-08,"d":"1.54E-08"},{"v":2.45e-09,"d":"2.45E-09"},-0.149654394,10.44705588,"Down"]
[117,"REACTOME_FIBRONECTIN_MATRIX_FORMATION",-6.002466408,-0.120706291,{"v":1.46e-08,"d":"1.46E-08"},{"v":2.32e-09,"d":"2.32E-09"},-0.044189791,10.50113845,"Down"]
[116,"BIOCARTA_PTC1_PATHWAY",-6.017040516,-0.078216644,{"v":1.34e-08,"d":"1.34E-08"},{"v":2.12e-09,"d":"2.12E-09"},-0.121639776,10.58673093,"Down"]
[115,"REACTOME_LDL_REMODELING",-6.021685852,-0.177106588,{"v":1.31e-08,"d":"1.31E-08"},{"v":2.06e-09,"d":"2.06E-09"},0.172789083,10.61405458,"Down"]
[114,"REACTOME_GLUCONEOGENESIS",-6.070915907,-0.073196504,{"v":9.87e-09,"d":"9.87E-09"},{"v":1.53e-09,"d":"1.53E-09"},-0.136066599,10.90487056,"Down"]
[113,"BIOCARTA_CDC25_PATHWAY",-6.096966653,-0.079044902,{"v":8.46e-09,"d":"8.46E-09"},{"v":1.3e-09,"d":"1.30E-09"},-0.062746585,11.05968137,"Down"]
[112,"REACTOME_ROLE_OF_SECOND_MESSENGERS_IN_NETRIN_1_SIGNALING",-6.112695678,-0.102659833,{"v":7.73e-09,"d":"7.73E-09"},{"v":1.18e-09,"d":"1.18E-09"},-0.107848393,11.15346232,"Down"]
[111,"REACTOME_THE_PHOTOTRANSDUCTION_CASCADE",-6.168740675,-0.054593585,{"v":5.5e-09,"d":"5.50E-09"},{"v":8.38e-10,"d":"8.38E-10"},0.138341399,11.48950674,"Down"]
[110,"REACTOME_CD163_MEDIATING_AN_ANTI_INFLAMMATORY_RESPONSE",-6.268083598,-0.095393978,{"v":3.02e-09,"d":"3.02E-09"},{"v":4.51e-10,"d":"4.51E-10"},-0.056484224,12.09240215,"Down"]
[109,"REACTOME_FATTY_ACYL_COA_BIOSYNTHESIS",-6.290449888,-0.04907468,{"v":2.65e-09,"d":"2.65E-09"},{"v":3.91e-10,"d":"3.91E-10"},-0.152295222,12.22941425,"Down"]
[108,"WP_LIVER_X_RECEPTOR_PATHWAY",-6.325799138,-0.089412191,{"v":2.14e-09,"d":"2.14E-09"},{"v":3.13e-10,"d":"3.13E-10"},0.018413783,12.44691224,"Down"]
[107,"WP_ALTERNATIVE_PATHWAY_OF_FETAL_ANDROGEN_SYNTHESIS",-6.428300044,-0.118039991,{"v":1.14e-09,"d":"1.14E-09"},{"v":1.63e-10,"d":"1.63E-10"},-0.050327526,13.08418663,"Down"]
[106,"WP_TYPE_II_DIABETES_MELLITUS",-6.439874953,-0.056886934,{"v":1.07e-09,"d":"1.07E-09"},{"v":1.51e-10,"d":"1.51E-10"},-0.104746327,13.15676728,"Down"]
[105,"REACTOME_HYALURONAN_BIOSYNTHESIS_AND_EXPORT",-6.442836609,-0.111647033,{"v":1.06e-09,"d":"1.06E-09"},{"v":1.48e-10,"d":"1.48E-10"},-0.129681751,13.17535848,"Down"]
[104,"WP_NUCLEAR_RECEPTORS_IN_LIPID_METABOLISM_AND_TOXICITY",-6.515845084,-0.061867141,{"v":6.76e-10,"d":"6.76E-10"},{"v":9.22e-11,"d":"9.22E-11"},0.078146464,13.63624042,"Down"]
[103,"REACTOME_P75NTR_REGULATES_AXONOGENESIS",-6.529306396,-0.124139374,{"v":6.2e-10,"d":"6.20E-10"},{"v":8.44e-11,"d":"8.44E-11"},-0.102228969,13.72176027,"Down"]
[102,"BIOCARTA_IL12_PATHWAY",-6.545781756,-0.061860779,{"v":5.6e-10,"d":"5.60E-10"},{"v":7.58e-11,"d":"7.58E-11"},0.163307383,13.82665806,"Down"]
[101,"REACTOME_NA_CL_DEPENDENT_NEUROTRANSMITTER_TRANSPORTERS",-6.626706881,-0.051199481,{"v":3.38e-10,"d":"3.38E-10"},{"v":4.45e-11,"d":"4.45E-11"},0.371431293,14.34557167,"Down"]
[100,"KEGG_PPAR_SIGNALING_PATHWAY",-6.633256871,-0.042092488,{"v":3.24e-10,"d":"3.24E-10"},{"v":4.26e-11,"d":"4.26E-11"},-0.0954799,14.38783836,"Down"]
[99,"BIOCARTA_PLK3_PATHWAY",-6.675765338,-0.092671366,{"v":2.48e-10,"d":"2.48E-10"},{"v":3.21e-11,"d":"3.21E-11"},-0.188254171,14.66311168,"Down"]
[98,"KEGG_LINOLEIC_ACID_METABOLISM",-6.719450314,-0.072521313,{"v":1.86e-10,"d":"1.86E-10"},{"v":2.4e-11,"d":"2.40E-11"},0.314126541,14.94775176,"Down"]
[97,"REACTOME_SIGNALING_BY_RNF43_MUTANTS",-6.802257082,-0.09207366,{"v":1.08e-10,"d":"1.08E-10"},{"v":1.37e-11,"d":"1.37E-11"},0.084243089,15.4921562,"Down"]
[96,"REACTOME_PLATELET_HOMEOSTASIS",-6.869358946,-0.042875214,{"v":6.88e-11,"d":"6.88E-11"},{"v":8.69e-12,"d":"8.69E-12"},-0.030178897,15.9379683,"Down"]
[95,"REACTOME_POU5F1_OCT4_SOX2_NANOG_REPRESS_GENES_RELATED_TO_DIFFERENTIATION",-6.877446386,-0.081448609,{"v":6.56e-11,"d":"6.56E-11"},{"v":8.22e-12,"d":"8.22E-12"},0.266284467,15.99198098,"Down"]
[94,"BIOCARTA_MAL_PATHWAY",-6.897134772,-0.082950871,{"v":5.77e-11,"d":"5.77E-11"},{"v":7.18e-12,"d":"7.18E-12"},-0.115906798,16.12372438,"Down"]
[93,"REACTOME_SEROTONIN_RECEPTORS",-6.906039809,-0.039721704,{"v":5.47e-11,"d":"5.47E-11"},{"v":6.76e-12,"d":"6.76E-12"},0.495215604,16.18342945,"Down"]
[92,"REACTOME_POU5F1_OCT4_SOX2_NANOG_ACTIVATE_GENES_RELATED_TO_PROLIFERATION",-6.916346902,-0.081206447,{"v":5.12e-11,"d":"5.12E-11"},{"v":6.3e-12,"d":"6.30E-12"},0.2046741,16.25262627,"Down"]
[91,"BIOCARTA_FLUMAZENIL_PATHWAY",-6.959551116,-0.13889389,{"v":3.83e-11,"d":"3.83E-11"},{"v":4.67e-12,"d":"4.67E-12"},0.164868678,16.54374597,"Down"]
[90,"KEGG_GLYCINE_SERINE_AND_THREONINE_METABOLISM",-6.977540223,-0.053432546,{"v":3.39e-11,"d":"3.39E-11"},{"v":4.12e-12,"d":"4.12E-12"},0.058605464,16.66546866,"Down"]
[89,"WP_SARSCOV2_AND_COVID19_PATHWAY",-7.002946609,-0.116284938,{"v":2.86e-11,"d":"2.86E-11"},{"v":3.46e-12,"d":"3.46E-12"},-0.116754142,16.83788864,"Down"]
[88,"BIOCARTA_CELLCYCLE_PATHWAY",-7.075972877,-0.064256353,{"v":1.76e-11,"d":"1.76E-11"},{"v":2.07e-12,"d":"2.07E-12"},-0.150552461,17.33679267,"Down"]
[87,"REACTOME_TRANSMISSION_ACROSS_CHEMICAL_SYNAPSES",-7.098950006,-0.027158973,{"v":1.51e-11,"d":"1.51E-11"},{"v":1.76e-12,"d":"1.76E-12"},-0.039792204,17.49478448,"Down"]
[86,"REACTOME_TERMINAL_PATHWAY_OF_COMPLEMENT",-7.099663096,-0.127540833,{"v":1.51e-11,"d":"1.51E-11"},{"v":1.76e-12,"d":"1.76E-12"},0.058740974,17.49969549,"Down"]
[85,"REACTOME_N_GLYCAN_ANTENNAE_ELONGATION_IN_THE_MEDIAL_TRANS_GOLGI",-7.100070877,-0.060873614,{"v":1.51e-11,"d":"1.51E-11"},{"v":1.75e-12,"d":"1.75E-12"},-0.058366694,17.50250406,"Down"]
[84,"REACTOME_REDUCTION_OF_CYTOSOLIC_CA_LEVELS",-7.164802992,-0.11371315,{"v":9.67e-12,"d":"9.67E-12"},{"v":1.11e-12,"d":"1.11E-12"},-0.029023978,17.95028281,"Down"]
[83,"REACTOME_PHASE_0_RAPID_DEPOLARISATION",-7.190545822,-0.051084592,{"v":8.12e-12,"d":"8.12E-12"},{"v":9.22e-13,"d":"9.22E-13"},0.088341593,18.12942676,"Down"]
[82,"REACTOME_ACTIVATION_OF_KAINATE_RECEPTORS_UPON_GLUTAMATE_BINDING",-7.210106967,-0.072007953,{"v":7.12e-12,"d":"7.12E-12"},{"v":8.01e-13,"d":"8.01E-13"},-0.001452931,18.26595931,"Down"]
[81,"REACTOME_SODIUM_CALCIUM_EXCHANGERS",-7.237320605,-0.092899733,{"v":5.97e-12,"d":"5.97E-12"},{"v":6.6e-13,"d":"6.60E-13"},0.145926975,18.45648869,"Down"]
[80,"WP_AMINO_ACID_METABOLISM_PATHWAY_EXCERPT_HISTIDINE_CATABOLISM_EXTENSION",-7.239290126,-0.136313821,{"v":5.9e-12,"d":"5.90E-12"},{"v":6.5e-13,"d":"6.50E-13"},0.127395948,18.47030416,"Down"]
[79,"BIOCARTA_TOB1_PATHWAY",-7.241357329,-0.078041946,{"v":5.84e-12,"d":"5.84E-12"},{"v":6.41e-13,"d":"6.41E-13"},-0.071686857,18.48480865,"Down"]
[78,"REACTOME_ERBB2_ACTIVATES_PTK6_SIGNALING",-7.334355942,-0.096629492,{"v":3.1e-12,"d":"3.10E-12"},{"v":3.27e-13,"d":"3.27E-13"},0.111239664,19.1413832,"Down"]
[77,"WP_PKCGAMMA_CALCIUM_SIGNALING_PATHWAY_IN_ATAXIA",-7.349346374,-0.076637302,{"v":2.79e-12,"d":"2.79E-12"},{"v":2.94e-13,"d":"2.94E-13"},-0.012861827,19.24795753,"Down"]
[76,"WP_ETHANOL_METABOLISM_PRODUCTION_OF_ROS_BY_CYP2E1",-7.3690779,-0.106429765,{"v":2.44e-12,"d":"2.44E-12"},{"v":2.54e-13,"d":"2.54E-13"},-0.238501819,19.38855202,"Down"]
[75,"REACTOME_ABACAVIR_TRANSPORT_AND_METABOLISM",-7.485304306,-0.094762675,{"v":1.07e-12,"d":"1.07E-12"},{"v":1.08e-13,"d":"1.08E-13"},0.025840828,20.22392811,"Down"]
[74,"REACTOME_REACTIONS_SPECIFIC_TO_THE_COMPLEX_N_GLYCAN_SYNTHESIS_PATHWAY",-7.577191386,-0.098944414,{"v":5.54e-13,"d":"5.54E-13"},{"v":5.47e-14,"d":"5.47E-14"},-0.024850036,20.89308707,"Down"]
[73,"REACTOME_SYNTHESIS_OF_15_EICOSATETRAENOIC_ACID_DERIVATIVES",-7.629408826,-0.13623042,{"v":3.78e-13,"d":"3.78E-13"},{"v":3.69e-14,"d":"3.69E-14"},0.114572287,21.27678051,"Down"]
[72,"WP_PPAR_SIGNALING_PATHWAY",-7.786268894,-0.047550941,{"v":1.19e-13,"d":"1.19E-13"},{"v":1.12e-14,"d":"1.12E-14"},-0.079741596,22.44427879,"Down"]
[71,"REACTOME_UNBLOCKING_OF_NMDA_RECEPTORS_GLUTAMATE_BINDING_AND_ACTIVATION",-7.790075903,-0.062017941,{"v":1.16e-13,"d":"1.16E-13"},{"v":1.09e-14,"d":"1.09E-14"},0.049068905,22.47289133,"Down"]
[70,"KEGG_PRION_DISEASES",-7.829517453,-0.085229495,{"v":8.66e-14,"d":"8.66E-14"},{"v":8.05e-15,"d":"8.05E-15"},-0.103464906,22.77009642,"Down"]
[69,"REACTOME_ION_HOMEOSTASIS",-7.838466542,-0.051406511,{"v":8.11e-14,"d":"8.11E-14"},{"v":7.51e-15,"d":"7.51E-15"},-0.0671095,22.83772665,"Down"]
[68,"WP_DRUG_INDUCTION_OF_BILE_ACID_PATHWAY",-7.867241215,-0.072793439,{"v":6.56e-14,"d":"6.56E-14"},{"v":6.01e-15,"d":"6.01E-15"},0.211797676,23.0556739,"Down"]
[67,"REACTOME_DEFECTIVE_GALNT3_CAUSES_HFTC",-7.885875098,-0.06045123,{"v":5.79e-14,"d":"5.79E-14"},{"v":5.2e-15,"d":"5.20E-15"},0.265118016,23.19721122,"Down"]
[66,"REACTOME_E2F_ENABLED_INHIBITION_OF_PRE_REPLICATION_COMPLEX_FORMATION",-7.939612972,-0.113780328,{"v":3.87e-14,"d":"3.87E-14"},{"v":3.43e-15,"d":"3.43E-15"},0.01503916,23.60714372,"Down"]
[65,"WP_VITAMIN_DSENSITIVE_CALCIUM_SIGNALING_IN_DEPRESSION",-8.040586779,-0.064325078,{"v":1.81e-14,"d":"1.81E-14"},{"v":1.55e-15,"d":"1.55E-15"},-0.019952504,24.38445263,"Down"]
[64,"REACTOME_PHASE_2_PLATEAU_PHASE",-8.057346095,-0.082857382,{"v":1.6e-14,"d":"1.60E-14"},{"v":1.36e-15,"d":"1.36E-15"},0.211429831,24.51435624,"Down"]
[63,"PID_CONE_PATHWAY",-8.119146311,-0.062317536,{"v":1e-14,"d":"1.00E-14"},{"v":8.32e-16,"d":"8.32E-16"},0.434262222,24.99556018,"Down"]
[62,"BIOCARTA_PLCD_PATHWAY",-8.137410257,-0.096825227,{"v":8.75e-15,"d":"8.75E-15"},{"v":7.19e-16,"d":"7.19E-16"},0.227814057,25.13842818,"Down"]
[61,"REACTOME_MINERALOCORTICOID_BIOSYNTHESIS",-8.25990117,-0.04308841,{"v":3.41e-15,"d":"3.41E-15"},{"v":2.69e-16,"d":"2.69E-16"},0.596846731,26.10433281,"Down"]
[60,"REACTOME_GABA_SYNTHESIS_RELEASE_REUPTAKE_AND_DEGRADATION",-8.265636549,-0.090453435,{"v":3.27e-15,"d":"3.27E-15"},{"v":2.57e-16,"d":"2.57E-16"},0.047484018,26.14988862,"Down"]
[59,"REACTOME_VITAMIN_C_ASCORBATE_METABOLISM",-8.276897869,-0.139677344,{"v":3e-15,"d":"3.00E-15"},{"v":2.34e-16,"d":"2.34E-16"},-0.068669111,26.23942228,"Down"]
[58,"REACTOME_NOREPINEPHRINE_NEUROTRANSMITTER_RELEASE_CYCLE",-8.277293654,-0.098127076,{"v":3e-15,"d":"3.00E-15"},{"v":2.33e-16,"d":"2.33E-16"},0.010535532,26.24257105,"Down"]
[57,"REACTOME_G2_PHASE",-8.30926724,-0.083918594,{"v":2.33e-15,"d":"2.33E-15"},{"v":1.8e-16,"d":"1.80E-16"},0.199279879,26.49740799,"Down"]
[56,"WP_BILE_ACIDS_SYNTHESIS_AND_ENTEROHEPATIC_CIRCULATION",-8.317475765,-0.146974299,{"v":2.19e-15,"d":"2.19E-15"},{"v":1.68e-16,"d":"1.68E-16"},-0.053123242,26.56297925,"Down"]
[55,"PID_ERBB_NETWORK_PATHWAY",-8.337490345,-0.103309188,{"v":1.89e-15,"d":"1.89E-15"},{"v":1.43e-16,"d":"1.43E-16"},0.064717538,26.72311186,"Down"]
[54,"REACTOME_ASPARTATE_AND_ASPARAGINE_METABOLISM",-8.372613802,-0.085296036,{"v":1.44e-15,"d":"1.44E-15"},{"v":1.07e-16,"d":"1.07E-16"},0.05940688,27.00499211,"Down"]
[53,"REACTOME_ANTIMICROBIAL_PEPTIDES",-8.421008027,-0.065052906,{"v":9.83e-16,"d":"9.83E-16"},{"v":7.22e-17,"d":"7.22E-17"},0.108047072,27.39517854,"Down"]
[52,"SA_G2_AND_M_PHASES",-8.454283747,-0.09580775,{"v":7.51e-16,"d":"7.51E-16"},{"v":5.49e-17,"d":"5.49E-17"},-0.053405514,27.66468044,"Down"]
[51,"REACTOME_NEUROTRANSMITTER_RECEPTORS_AND_POSTSYNAPTIC_SIGNAL_TRANSMISSION",-8.471437502,-0.038986196,{"v":6.54e-16,"d":"6.54E-16"},{"v":4.76e-17,"d":"4.76E-17"},-0.044388898,27.80399478,"Down"]
[50,"REACTOME_NEURONAL_SYSTEM",-8.501800084,-0.023430571,{"v":5.11e-16,"d":"5.11E-16"},{"v":3.7e-17,"d":"3.70E-17"},0.022755847,28.05122651,"Down"]
[49,"WP_INTERACTIONS_OF_NATURAL_KILLER_CELLS_IN_PANCREATIC_CANCER",-8.532122955,-0.087650392,{"v":4.03e-16,"d":"4.03E-16"},{"v":2.88e-17,"d":"2.88E-17"},0.025901524,28.29895298,"Down"]
[48,"REACTOME_ALPHA_DEFENSINS",-8.543741773,-0.092031801,{"v":3.67e-16,"d":"3.67E-16"},{"v":2.61e-17,"d":"2.61E-17"},0.171263541,28.39409087,"Down"]
[47,"REACTOME_PI3K_EVENTS_IN_ERBB4_SIGNALING",-8.635506162,-0.135220345,{"v":1.73e-16,"d":"1.73E-16"},{"v":1.21e-17,"d":"1.21E-17"},0.037788467,29.14969133,"Down"]
[46,"WP_EFFECTS_OF_NITRIC_OXIDE",-8.835964465,-0.115930272,{"v":3.25e-17,"d":"3.25E-17"},{"v":2.2e-18,"d":"2.20E-18"},0.367782793,30.82621633,"Down"]
[45,"WP_CODEINE_AND_MORPHINE_METABOLISM",-8.913059881,-0.069052293,{"v":1.72e-17,"d":"1.72E-17"},{"v":1.13e-18,"d":"1.13E-18"},0.383254746,31.48043888,"Down"]
[44,"REACTOME_SIGNALLING_TO_P38_VIA_RIT_AND_RIN",-8.919249166,-0.140479748,{"v":1.64e-17,"d":"1.64E-17"},{"v":1.07e-18,"d":"1.07E-18"},-0.191781277,31.53318719,"Down"]
[43,"REACTOME_ELEVATION_OF_CYTOSOLIC_CA2_LEVELS",-8.982622894,-0.108639002,{"v":9.65e-18,"d":"9.65E-18"},{"v":6.17e-19,"d":"6.17E-19"},-0.062086763,32.07522786,"Down"]
[42,"WP_METABOLISM_OF_ALPHALINOLENIC_ACID",-8.990703341,-0.101832437,{"v":9.04e-18,"d":"9.04E-18"},{"v":5.75e-19,"d":"5.75E-19"},0.156235295,32.14459407,"Down"]
[41,"REACTOME_SYNTHESIS_OF_12_EICOSATETRAENOIC_ACID_DERIVATIVES",-9.010832421,-0.164964729,{"v":7.62e-18,"d":"7.62E-18"},{"v":4.83e-19,"d":"4.83E-19"},0.246286289,32.31764024,"Down"]
[40,"BIOCARTA_GRANULOCYTES_PATHWAY",-9.247354895,-0.074864683,{"v":1e-18,"d":"1.00E-18"},{"v":5.95e-20,"d":"5.95E-20"},0.403385103,34.37754339,"Down"]
[39,"REACTOME_ERBB2_REGULATES_CELL_MOTILITY",-9.253961366,-0.11835322,{"v":9.51e-19,"d":"9.51E-19"},{"v":5.61e-20,"d":"5.61E-20"},0.047403102,34.435781,"Down"]
[38,"BIOCARTA_GABA_PATHWAY",-9.294285228,-0.141018458,{"v":6.7e-19,"d":"6.70E-19"},{"v":3.9e-20,"d":"3.90E-20"},-0.10698749,34.79206918,"Down"]
[37,"KEGG_TASTE_TRANSDUCTION",-9.346456666,-0.06618801,{"v":4.21e-19,"d":"4.21E-19"},{"v":2.44e-20,"d":"2.44E-20"},0.18330123,35.25513706,"Down"]
[36,"REACTOME_MET_RECEPTOR_ACTIVATION",-9.347201834,-0.146998764,{"v":4.21e-19,"d":"4.21E-19"},{"v":2.42e-20,"d":"2.42E-20"},0.096036738,35.26176822,"Down"]
[35,"REACTOME_METAL_SEQUESTRATION_BY_ANTIMICROBIAL_PROTEINS",-9.415556206,-0.149417897,{"v":2.32e-19,"d":"2.32E-19"},{"v":1.3e-20,"d":"1.30E-20"},0.096999747,35.87209525,"Down"]
[34,"REACTOME_ELECTRIC_TRANSMISSION_ACROSS_GAP_JUNCTIONS",-9.458525574,-0.173339113,{"v":1.58e-19,"d":"1.58E-19"},{"v":8.81e-21,"d":"8.81E-21"},0.106200343,36.25783658,"Down"]
[33,"REACTOME_CDC6_ASSOCIATION_WITH_THE_ORC_ORIGIN_COMPLEX",-9.459899564,-0.116496461,{"v":1.57e-19,"d":"1.57E-19"},{"v":8.7e-21,"d":"8.70E-21"},0.039873632,36.27019744,"Down"]
[32,"REACTOME_BIOSYNTHESIS_OF_MARESINS",-9.698915113,-0.089727728,{"v":1.87e-20,"d":"1.87E-20"},{"v":9.56e-22,"d":"9.56E-22"},0.334351418,38.44526898,"Down"]
[31,"WP_FATTY_ACID_TRANSPORTERS",-9.960783559,-0.104720768,{"v":1.8e-21,"d":"1.80E-21"},{"v":8.05e-23,"d":"8.05E-23"},-0.04041501,40.88465906,"Down"]
[30,"REACTOME_BICARBONATE_TRANSPORTERS",-10.08949579,-0.12419535,{"v":5.5e-22,"d":"5.50E-22"},{"v":2.33e-23,"d":"2.33E-23"},0.050741034,42.10511698,"Down"]
[29,"WP_NICOTINE_EFFECT_ON_DOPAMINERGIC_NEURONS",-10.14117997,-0.123083229,{"v":3.36e-22,"d":"3.36E-22"},{"v":1.41e-23,"d":"1.41E-23"},0.129068489,42.59915197,"Down"]
[28,"KEGG_OLFACTORY_TRANSDUCTION",-10.32142847,-0.091471857,{"v":6.2e-23,"d":"6.20E-23"},{"v":2.42e-24,"d":"2.42E-24"},0.088986734,44.3397965,"Down"]
[27,"BIOCARTA_BOTULIN_PATHWAY",-10.35982602,-0.237438427,{"v":4.28e-23,"d":"4.28E-23"},{"v":1.66e-24,"d":"1.66E-24"},0.083248815,44.71414248,"Down"]
[26,"REACTOME_IONOTROPIC_ACTIVITY_OF_KAINATE_RECEPTORS",-10.42913183,-0.143581032,{"v":2.23e-23,"d":"2.23E-23"},{"v":8.32e-25,"d":"8.32E-25"},0.034581221,45.39296119,"Down"]
[25,"REACTOME_CARDIAC_CONDUCTION",-10.59866635,-0.052143084,{"v":4.34e-24,"d":"4.34E-24"},{"v":1.52e-25,"d":"1.52E-25"},0.036917314,47.07046402,"Down"]
[24,"WP_SCFA_AND_SKELETAL_MUSCLE_SUBSTRATE_METABOLISM",-10.71052803,-0.140394365,{"v":1.45e-24,"d":"1.45E-24"},{"v":4.89e-26,"d":"4.89E-26"},0.346233136,48.19046533,"Down"]
[23,"REACTOME_TYROSINE_CATABOLISM",-11.10265016,-0.226338427,{"v":2.91e-26,"d":"2.91E-26"},{"v":8.44e-28,"d":"8.44E-28"},0.108769696,52.19853119,"Down"]
[22,"REACTOME_OPSINS",-11.15501742,-0.111201295,{"v":1.74e-26,"d":"1.74E-26"},{"v":4.86e-28,"d":"4.86E-28"},0.341587283,52.74339856,"Down"]
[21,"REACTOME_SYNAPTIC_ADHESION_LIKE_MOLECULES",-11.30177752,-0.138578012,{"v":3.94e-27,"d":"3.94E-27"},{"v":1.02e-28,"d":"1.02E-28"},-0.084379793,54.28236589,"Down"]
[20,"REACTOME_PROTEIN_PROTEIN_INTERACTIONS_AT_SYNAPSES",-11.37989006,-0.069964094,{"v":1.78e-27,"d":"1.78E-27"},{"v":4.43e-29,"d":"4.43E-29"},-0.05228925,55.10864607,"Down"]
[19,"REACTOME_LONG_TERM_POTENTIATION",-11.46176747,-0.100374025,{"v":7.57e-28,"d":"7.57E-28"},{"v":1.83e-29,"d":"1.83E-29"},0.095471725,55.98007922,"Down"]
[18,"REACTOME_THE_RETINOID_CYCLE_IN_CONES_DAYLIGHT_VISION",-11.56118994,-0.146291229,{"v":2.69e-28,"d":"2.69E-28"},{"v":6.24e-30,"d":"6.24E-30"},0.220619336,57.04555627,"Down"]
[17,"REACTOME_PLATELET_CALCIUM_HOMEOSTASIS",-11.71908104,-0.1360993,{"v":4.98e-29,"d":"4.98E-29"},{"v":1.11e-30,"d":"1.11E-30"},0.019283952,58.7540297,"Down"]
[16,"REACTOME_FORMATION_OF_THE_CORNIFIED_ENVELOPE",-11.79910159,-0.10526929,{"v":2.16e-29,"d":"2.16E-29"},{"v":4.58e-31,"d":"4.58E-31"},-0.012338875,59.62755619,"Down"]
[15,"REACTOME_ABACAVIR_TRANSMEMBRANE_TRANSPORT",-11.96977506,-0.150434609,{"v":3.56e-30,"d":"3.56E-30"},{"v":6.83e-32,"d":"6.83E-32"},0.243911647,61.50779985,"Down"]
[14,"REACTOME_NEUREXINS_AND_NEUROLIGINS",-12.14514946,-0.092045927,{"v":5.5e-31,"d":"5.50E-31"},{"v":9.45e-33,"d":"9.45E-33"},0.022352347,63.46399483,"Down"]
[13,"WP_SULFATION_BIOTRANSFORMATION_REACTION",-12.28901358,-0.177272936,{"v":1.18e-31,"d":"1.18E-31"},{"v":1.83e-33,"d":"1.83E-33"},0.071465763,65.08688677,"Down"]
[12,"REACTOME_KERATINIZATION",-12.71247877,-0.116433266,{"v":1.13e-33,"d":"1.13E-33"},{"v":1.33e-35,"d":"1.33E-35"},0.012820886,69.95806643,"Down"]
[11,"WP_GPCRS_CLASS_C_METABOTROPIC_GLUTAMATE_PHEROMONE",-13.09145446,-0.173530294,{"v":1.38e-35,"d":"1.38E-35"},{"v":1.44e-37,"d":"1.44E-37"},0.214297546,74.43524843,"Down"]
[10,"REACTOME_CLASS_C_3_METABOTROPIC_GLUTAMATE_PHEROMONE_RECEPTORS",-13.29884361,-0.151126047,{"v":1.18e-36,"d":"1.18E-36"},{"v":1.16e-38,"d":"1.16E-38"},0.337407106,76.93179282,"Down"]
[9,"REACTOME_REVERSIBLE_HYDRATION_OF_CARBON_DIOXIDE",-13.47181043,-0.166455961,{"v":1.7e-37,"d":"1.70E-37"},{"v":1.38e-39,"d":"1.38E-39"},0.280167536,79.03884531,"Down"]
[8,"REACTOME_INTESTINAL_ABSORPTION",-13.6397855,-0.13015677,{"v":2.2e-38,"d":"2.20E-38"},{"v":1.7e-40,"d":"1.70E-40"},0.245193982,81.1065873,"Down"]
[7,"REACTOME_CYP2E1_REACTIONS",-14.20652035,-0.133870657,{"v":2.22e-41,"d":"2.22E-41"},{"v":1.27e-43,"d":"1.27E-43"},0.471627254,88.23731659,"Down"]
[6,"REACTOME_DIGESTION_OF_DIETARY_LIPID",-14.96883537,-0.241872368,{"v":1.35e-45,"d":"1.35E-45"},{"v":5.47e-48,"d":"5.47E-48"},0.265847719,98.19635677,"Down"]
[5,"REACTOME_PRESYNAPTIC_NICOTINIC_ACETYLCHOLINE_RECEPTORS",-15.42256559,-0.165425533,{"v":4.81e-48,"d":"4.81E-48"},{"v":1.14e-50,"d":"1.14E-50"},0.450314583,104.3188564,"Down"]
[4,"REACTOME_BIOSYNTHESIS_OF_MARESIN_LIKE_SPMS",-15.49066664,-0.206909163,{"v":2.19e-48,"d":"2.19E-48"},{"v":4.44e-51,"d":"4.44E-51"},0.409163057,105.2500965,"Down"]
[3,"REACTOME_ACETYLCHOLINE_BINDING_AND_DOWNSTREAM_EVENTS",-15.54722255,-0.175692687,{"v":1.2e-48,"d":"1.20E-48"},{"v":2.03e-51,"d":"2.03E-51"},0.470510612,106.0258829,"Down"]
[2,"REACTOME_HIGHLY_CALCIUM_PERMEABLE_NICOTINIC_ACETYLCHOLINE_RECEPTORS",-15.65870763,-0.202185637,{"v":3.2e-49,"d":"3.20E-49"},{"v":4.31e-52,"d":"4.31E-52"},0.524196194,107.5615451,"Down"]
[1,"REACTOME_HIGHLY_CALCIUM_PERMEABLE_POSTSYNAPTIC_NICOTINIC_ACETYLCHOLINE_RECEPTORS",-15.68204883,-0.202498218,{"v":3.08e-49,"d":"3.08E-49"},{"v":3.11e-52,"d":"3.11E-52"},0.524382441,107.8841331,"Down"]