Supplementary material S4. GO and KEGG pathway analysis of differentially expressed genes.
Category	ID	Term	Count	%	PValue	Genes	List Total	Pop Hits	Pop Total	Fold Enrichment	Bonferroni	Benjamini	FDR
MF	GO:0005515~protein binding	protein binding	553	53.68932039	7.20E-04	CNTFR, TLNRD1, TFRC, WIPF1, WIPF2, RAPH1, ELK3, FAM110A, PREX1, LIPE, EVA1A, SOX17, UBASH3B, TMEM88, GJA5, GJA4, PGAP6, LUC7L, RTTN, PRKACA, IER5, CUBN, CXADR, WSB1, UNC5B, LDOC1, RNASE2, HSPG2, EML3, ACE2, RNF125, DAAM2, CLDN8, ADPRH, DDIT4, ORAI1, HOXB5, FICD, HHLA2, PDGFB, GATA5, GATA3, CFP, ACMSD, RRP7A, S100A16, AGMO, RDH10, S100A12, HOXC4, NCKAP1L, PPARGC1A, HAO2, SLC19A2, PROSER3, CTC1, LYN, JUP, NEBL, BTBD18, CYP4F2, SLC16A12, NFATC2, NFATC1, NR1D1, PRRC2A, EHD2, H1-4, EHD4, GIPC3, GIPC2, SERPINI2, NOX4, SNAI2, HOXD3, FXYD5, HRG, OGFR, RARG, SIGLEC9, TINAGL1, ARPC1B, TGFB1I1, PYGL, LRRC32, DDA1, SERPINA5, SULT1C2, SHE, NHSL2, TMSB4Y, COL10A1, RNF152, ZNF366, OFD1, BATF2, UPF1, DUSP1, TET2, BGN, EMP2, TMEM174, GOLGA2P5, DUSP7, NCOR2, GJD3, RILPL2, SLC7A9, RAPGEF1, CDC42EP1, HCLS1, PLEKHO1, NUP62CL, HCST, ZNF596, ENG, C11ORF54, GRAMD1A, ASCL3, NFIX, AFM, SNX30, RIDA, FGD5, APOL6, UCP2, JAM3, SMAGP, F11, GPR52, LAPTM5, BBOX1, FMO1, SCAF1, SKI, GATM, STING1, ABI3, ETNK2, TAOK2, TSR2, PLP1, ZYX, ANKS4B, PLCD1, EXOC3L2, CSF1, PLXND1, RAB3D, PDCD5, SLC8A1, HID1, PYCARD, STK10, CDH5, TUBB6, GRB14, IYD, SLC16A9, KPNA2, RNF44, SLC15A2, CISH, FAM24B, USP5, IGFBP4, IGFBP2, USP2, PIPOX, TAP1, NEAT1, RAB31, STIM1, TEX9, MAK, RAB35, FSCN1, SRSF5, RHCG, CLEC4E, ANKRD36B, FKBP5, LY6E, PFKFB2, LRRC59, CSF1R, KMT2D, SEMA7A, NOTCH1, CD151, NOTCH4, SLC38A11, RHEX, SLC9A1, SLC9A3R2, TBXA2R, PLXNA2, ANKRD10, THEM4, SLC38A9, IGFBP6, SLC15A3, IP6K3, SLC38A4, TIA1, BTN2A2, WFS1, ZG16B, CCDC14, ZBTB16, ESRRG, G6PC1, CHERP, DRAP1, MAFB, ALB, BCL3, CDK2, PLEKHM2, ESAM, RNF186, OGT, NES, MAP3K11, FLT1, FLT4, DYSF, FHL3, NRARP, ECE1, FTCD, BICD2, PIK3C2B, SPN, SART1, THBD, HHEX, DUSP10, ADAMTS1, IQUB, BOC, PHACTR3, ZNF524, UPP2, SOST, SLC37A4, BOK, SLC13A2, PLEKHG2, DTX3L, TMEM255B, VPS37B, INMT, C1QL1, PTP4A3, PCCA, RTN4RL1, CTDSP1, LCP2, CCDC43, ITGA5, FXN, ASPA, HDAC5, PLEKHH2, ACSS3, SLC47A1, CEBPD, UNC93B1, RAB1B, SEMA3G, MLLT1, FOXK1, FURIN, LRP2, CYP3A5, VXN, PPM1F, HDAC7, POLR2A, CCDC85B, LRRC8C, HNRNPA1, SH2B3, SLC12A3, PTPN18, PPIL1, TIE1, SEMA4C, SEMA4G, MCOLN1, KLF2, PML, TBX3, GOLGA8DP, TSPAN14, MYO1C, SYT11, IL2RB, CD248, PTPN7, TPT1, ERRFI1, JPT1, THUMPD2, MT1X, ANTXR1, ICAM1, RUSC2, RASSF3, ADGRA2, CHORDC1, PDK4, KDR, CPNE2, CCNL1, SOX7, EPHB4, IL15RA, SLC6A19, TMEM52B, RSAD2, TAS2R10, IL1R2, FLT3LG, ANK2, ANK3, CSNK1E, AZGP1, SPATA17, MT1A, PLPP4, MXRA8, PLPP3, ATP6V0D2, TP53, MT1E, SLC22A5, GARRE1, GYPC, MAOA, SDC3, TWF2, PCDH17, PKHD1, INPP5D, ZNF703, INPP5K, ATP6V0A4, RALGDS, ARGLU1, PCK2, VAT1, APOBEC3F, GADD45A, IQSEC1, TNFSF12, SIGLEC10, EAF2, PILRA, BST2, ID1, TRMT11, ITM2C, ACVRL1, CSRNP1, SLC35F6, ROBO4, ECM1, CLIC3, SECTM1, HBB, PPP1R18, CX3CL1, MYDGF, ESM1, HNF4A, ENC1, CHMP1A, RAC2, CD34, PRMT6, MAP4K2, FCER1G, TNFRSF12A, HBA2, HBA1, AJAP1, MTSS2, MN1, PACS1, KIT, CD48, ALDOB, ARHGEF2, FOXC2, RAMP2, TAGLN, SLC43A3, NEDD9, RASIP1, RELA, PBLD, MNT, RANBP3L, NFIL3, LMNA, SUSD3, AHSA2P, CBR3, NPDC1, CAVIN1, DMRT2, CAVIN3, VEGFC, MYO9B, LILRB1, AXL, GSTA2, FCN1, FCN3, RIPOR1, UBXN2B, GIMAP1, C4ORF19, PLAT, OGDHL, CMIP, CCND1, ARHGDIA, DENND5A, TGM2, PDGFRB, SPINK1, HGD, CYBB, SHISA4, SHISA3, ATP1B2, PRLR, GEM, SCNN1G, SELENON, TYROBP, SLFN11, COL4A2, ADAM15, TBC1D20, COL4A1, ADAM12, APLNR, LYG2, LMX1B, DDX5, GSTCD, LTBP4, GLYAT, PLD3, DPP3, DPP4, EFNB2, EFNB1, GRK2, WNT3, MARK2, IVNS1ABP, MGAM, CBX6, NIBAN2, TGFB1, TRPV2, GGH, ISG15, SSC5D, USB1, CLK4, ACSF2, CLK1, BMP2, BAMBI, NABP1, LRP10, MXD4, DOCK6, ATP2A3, TNFAIP1, RND3, ACSM2B, PPP1R9B, LYL1, CYP26B1, CALB1, ADGRE5, BLNK, PDE4A, SCARF1, TAS2R5, CFAP44, ABCC2, ARHGEF15, PDE4D, PLA2G4C, PLAUR, PPP2R5B, ARAP3, FGR, ARHGAP10, OAS1, OAS2, ELF4, PEAK1, IRF1, CDHR2, IFIT1B, LUC7L3, SHANK3, CLRN3, ATP6V1B1, DDC, SAMHD1, LTC4S, STRN4, ASB15, PSMB10, DDN, DLL4, CAND2, TAF1D, GNG2, RASD1, HLX, GNA11, GNG7, NRIP2, NCAM1, S1PR3, S1PR2, SLIT2, S1PR4, GBP3, RRM2, NOS3, EGF, PRAF2, EYA4, SPRY4, MEIS2, SH3YL1, CD4, TEC, TCIM, CDK2AP2, ATP13A2	768	12539	18811	1.080221688	0.52401826	0.132306059	0.131406892
MF	GO:0042802~identical protein binding	identical protein binding	87	8.446601942	0.024077731	TLNRD1, CSF1, TFRC, PYGL, TNFAIP1, OLFML2A, PYCARD, STK10, RASSF3, UBASH3B, CHMP1A, KDR, LUC7L, UPP2, IER5, TGM2, OFD1, FCER1G, CXADR, HGD, USP2, C1QL3, ACE2, TYROBP, PLPP4, STIM1, RILPL2, PEAK1, CLDN8, ORAI1, ALDOB, RHCG, ASPA, TP53, ANKRD36B, PVALB, ENG, HDAC5, FOXC2, NOTCH1, FICD, CEBPD, SDC3, PDGFB, GATA3, SAMHD1, LTC4S, RELA, CRYZ, PBLD, SLC9A3R2, DPP4, RIDA, TAF1D, NFIL3, LMNA, PLXNA2, S100A12, SLIT2, IGFBP6, HNRNPA1, GBP3, TGFB1, APOBEC3F, CAVIN1, DMRT2, ZBTB16, F11, BBOX1, ESRRG, LYZ, MCOLN1, PML, BST2, DRAP1, SKI, EHD2, CD4, MAFB, STING1, ABI3, SYT11, GIPC2, ID1, ALB, PLP1, MAP3K11	768	1712	18811	1.244704202	1	0.688890647	0.684208866
MF	GO:0008270~zinc ion binding	zinc ion binding	49	4.757281553	0.022235567	RARG, RNPEPL1, HNF4G, MT1X, ECE1, CALB1, ADAMTS1, HNF4A, CHORDC1, CHMP1A, ENPP3, ZCCHC24, UPF1, USP5, BHMT2, TET2, ACE2, MT1A, RNF125, ARHGEF2, SHANK3, TP53, MT1E, C11ORF54, AFM, GATA5, GATA3, SAMHD1, ADH6, CRYZ, DPP3, ACMSD, ZMAT1, S100A12, VAT1, APOBEC3F, BBOX1, MYO9B, ESRRG, ADA2, NR1D1, PML, SKI, CD4, BHMT, ZNFX1, ALB, ATP13A2, HRG	768	873	18811	1.374777766	1	0.673606897	0.669028986
MF	GO:0042803~protein homodimerization activity	protein homodimerization activity	46	4.466019417	0.002554182	CSF1R, FICD, CSF1, HSPB6, TFRC, GLDC, FLT4, PDGFB, ECE1, RASIP1, RELA, DPP4, PYCARD, STK10, HHEX, S100A16, HNF4A, CHMP1A, UGT1A4, MUC13, SLIT2, ST3GAL2, GBP3, BOK, UGT1A6, JAM3, CUBN, FCER1G, RRM2, JUP, GADD45A, ZBTB16, TAP1, ADA2, LILRB1, UPB1, SLC8B1, PML, BST2, CD4, TYROBP, STING1, KIT, HPD, MAP3K11, ENG	768	713	18811	1.580225134	0.928221714	0.239164342	0.237538953
MF	GO:0005509~calcium ion binding	calcium ion binding	46	4.466019417	0.00656416	PCDHB18P, NOTCH1, DNAH7, NOTCH4, DYSF, LTBP4, LRP2, PCDH12, DOC2B, NID1, CDH9, SLC8A1, PCDH17, RYR3, NBPF26, DLL4, THBD, CDH5, NHSL2, CALB1, SCIN, ADGRE5, S100A16, CHORDC1, S100A12, SLIT2, ENPP3, TGM2, CUBN, EGF, PLA2G4C, PCDHA12, HSPG2, H1-4, SELENON, EHD2, EHD4, STIM1, SYT11, CDHR2, DCHS1, CD248, CLEC4E, TPT1, PLCD1, PVALB	768	752	18811	1.498271969	0.998867552	0.482934658	0.479652578
MF	GO:0005102~receptor binding	receptor binding	33	3.203883495	1.95E-04	FCN1, CNTFR, HHLA2, FGL2, SEMA3G, ADM, PLAT, MST1L, CX3CL1, SLC9A3R2, DPP4, CDH5, HNF4A, IGFBP6, PPARGC1A, BOK, INSL4, LYN, PDGFRB, CXADR, BTN2A2, IGFBP4, TNFSF12, IGFBP2, PLAUR, FLT3LG, C1QL1, FGR, BMP2, TYROBP, MYO1C, HRG, HCST	768	396	18811	2.041124132	0.181728664	0.066847255	0.066392953
MF	GO:0001228~transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding	27	2.621359223	0.076669992	CSRNP1, FOXC2, CEBPD, HNF4G, GATA3, TFCP2L1, RELA, ELK3, HHEX, SOX17, SOX18, HNF4A, HOXC4, DMRT2, ZBTB16, NFATC2, NFATC1, ESRRG, MEIS2, TBX3, MAFB, DMTF1, ELF4, IRF1, HOXD3, TP53, HOXB5	768	473	18811	1.398148454	1	1	0.994169096
MF	GO:0003779~actin binding	actin binding	24	2.330097087	0.012108739	TMOD1, PLEKHH2, TLNRD1, WIPF1, NEBL, WIPF2, ARPC1B, TWF2, FHL3, MYO9B, PPP1R18, PPP1R9B, MTSS2, FMNL3, MYO1C, SCIN, DAAM2, CLMN, ENC1, FSCN1, PHACTR3, HCLS1, FXYD5, SHANK3	768	339	18811	1.73405236	0.999996448	0.593568713	0.589534751
MF	GO:0019899~enzyme binding	enzyme binding	24	2.330097087	0.049434247	LYN, PDGFRB, ECM1, DDC, DDX5, TGFB1, NOTCH1, DTX3L, GLDC, PDE4D, PLAUR, ANK2, RELA, PYCARD, PREX1, TSPAN14, CD4, PCCA, CCND1, BLNK, UGT1A4, TP53, SLC27A2, UGT1A6	768	390	18811	1.507291667	1	1	0.994169096
MF	GO:0005525~GTP binding	GTP binding	24	2.330097087	0.060652588	RERGL, RAB3D, RAB1B, GIMAP1, RHOF, GIMAP6, SAMHD1, RND3, GEM, GIMAP8, H1-4, EHD2, TUBB6, GVINP1, RASD1, RAB31, EHD4, GNA11, RAB35, RAC2, PCK1, GBP3, TGM2, PCK2	768	399	18811	1.473292607	1	1	0.994169096
CC	GO:0005886~plasma membrane	plasma membrane	275	26.69902913	1.36E-06	CNTFR, ERRFI1, TAS2R20, TFRC, GLDC, WIPF2, RAPH1, MRGPRF, ANTXR1, ICAM1, PREX1, EVA1A, RASSF3, TMEM88, ADGRA2, PGAP6, KDR, CPNE2, PRKACA, EPHB4, IL15RA, CUBN, SLC6A19, CXADR, UNC5B, TAS2R10, IL1R2, TAS2R14, FLT3LG, ANK2, ANK3, HSPG2, ACE2, PLPP4, CLDN8, MXRA8, ORAI1, PLPP3, CDC42SE1, TMEM161B, SLC22A5, GYPC, SDC3, PCDH12, CFP, PCDH17, S100A16, INPP5D, KCNMB1, INPP5K, S100A12, ATP6V0A4, NCKAP1L, SCN3A, RALGDS, TRPM3, SLC19A2, LYN, JUP, TAS2R31, ABCA5, SURF2, TNFSF12, MCAM, SIGLEC10, SLC16A12, PILRA, PRRC2A, BST2, EHD2, EHD4, NOX4, SLC22A8, HRG, ITM2C, ACVRL1, ROBO4, SIGLEC9, TGFB1I1, SECTM1, GRIK1, DOC2B, RYR3, CX3CL1, KCNT2, CHMP1A, GNRHR, RAC2, MUC13, CD34, ZNF366, FCER1G, TNFRSF12A, EMP2, RHOF, GPRC5B, SLC7A7, SLC7A9, KIT, RAPGEF1, CDC42EP1, HCLS1, CD48, HCST, ENG, RAMP2, GRAMD1A, PTGER3, NEDD9, FGD5, SUSD3, ATP6V1G3, SLC17A1, NKTR, JAM3, NPDC1, CAVIN1, SMAGP, F11, LILRB1, GPR4, SLC8B1, SLCO3A1, STING1, AXL, STK17B, ZYX, PLP1, ANKS4B, PLCD3, SLC28A2, PLCD1, NRROS, PLXND1, CSF1, GPR65, RAB3D, FOLH1B, CDH9, OR2T10, SLC8A1, CXCL16, STK10, CDH5, GRB14, IYD, RGS1, SLC16A9, TGM2, PDGFRB, SLC15A2, CISH, KCNH6, CYBB, ATP1B2, PCDHA12, PRLR, GEM, SCNN1G, SLC9A4, TYROBP, RAB31, ADAM15, STIM1, RAB35, ADAM12, SLCO2A1, APLNR, CLEC4E, RHCG, SLC27A2, LY6E, CSF1R, SEMA7A, NOTCH1, CD151, NOTCH4, ARHGEF28, NID1, RHEX, SLC9A1, SLC9A3R2, DPP4, EFNB2, EFNB1, GRK2, TBXA2R, PLXNA2, THEM4, WNT3, MARK2, SLC38A4, MGAM, NIBAN2, TGFB1, BTN2A2, CNTN5, ZBTB16, TRPV2, LRFN3, BMP2, BAMBI, BCL3, ESAM, LRP10, OGT, FLT1, FLT4, DYSF, SLC2A2, ECE1, RND3, FTCD, BICD2, PIK3C2B, PPP1R9B, SPN, THBD, ADGRE5, BOC, BLNK, PDE4A, TAS2R3, SCARF1, TAS2R5, SLC13A2, SLC36A2, ABCC2, PDE4D, PLA2G4C, PLAUR, ARAP3, VPS37B, FGR, ARHGAP10, PTP4A3, RTN4RL1, ITGA8, ITGA5, PLEKHH2, SLC47A1, SLC5A12, FURIN, SLC5A10, LRP2, SAMHD1, VXN, DLL4, GNG2, RASD1, MARVELD1, GNA11, GNG7, LRRC8C, NCAM1, S1PR3, S1PR2, SH2B3, S1PR4, SLC12A3, NOS3, EGF, KCNJ13, OR51E2, KCNJ16, MCOLN1, FMNL3, TSPAN14, CD4, MYO1C, FRAS1, TEC, TCIM, SYT11, IL2RB	865	5066	20472	1.284729433	7.52E-04	1.51E-04	1.48E-04
CC	GO:0016021~integral component of membrane	integral component of membrane	247	23.98058252	0.085785091	TAS2R20, TFRC, MRGPRF, ANTXR1, ICAM1, CYP4Z1, GJA3, EVA1A, TMEM88, ADGRA2, GJA5, GJA4, PGAP6, RTTN, IL15RA, SLC6A19, TMEM52B, UNC5B, TAS2R10, IL1R2, TAS2R14, FLT3LG, CSNK1E, ACE2, ABCA10, PLPP4, CLDN8, MXRA8, ORAI1, KDELR3, PLPP3, TP53, TMEM161B, SLC22A5, FICD, MAOA, HHLA2, SDC3, PCDH12, PCDH17, ACMSD, PKHD1, HSD11B2, RDH10, AGMO, ATP6V0A4, SCN3A, TRPM3, ST3GAL2, SLC19A2, VAT1, TMEM184B, TAS2R31, ABCA5, LRRN2, MCAM, CYP4F2, SIGLEC10, SLC16A12, PILRA, BST2, NOX4, DCHS1, FXYD5, SLC22A8, ITM2C, ACVRL1, CSRNP1, SLC35F6, ROBO4, RARG, SIGLEC9, PTPRQ, SECTM1, HBB, GRIK1, LRRC32, RYR3, CX3CL1, KCNT2, GNRHR, MUC13, RNF152, CD34, OFD1, MAP4K2, FCER1G, TNFRSF12A, EMP2, TMEM174, GPRC5B, GJD3, SLC7A7, KIT, CD48, HCST, ENG, RAMP2, GRAMD1A, SLC43A3, PTGER3, RFNG, SCARNA17, APOL6, UCP2, SUSD3, SLC17A1, TP53I11, SLC17A4, NPDC1, SMAGP, DMRT2, GPR52, LAPTM5, FMO1, LILRB1, CYP8B1, SLC8B1, SLCO3A1, STING1, AXL, TAOK2, PLP1, TMEM39B, NRROS, CSF1, GPR65, GIMAP1, MPV17L2, GXYLT2, CDH9, OR2T10, SLC8A1, CXCL16, CDH5, IYD, ENPP3, SLC16A9, FADS1, PDGFRB, SLC15A2, KCNH6, CYBB, TAP1, SHISA4, SHISA3, PCDHA12, PRLR, MPEG1, SLC9A4, TYROBP, ADAM15, MFNG, ADAM12, SLCO2A1, APLNR, CLEC4E, SLC27A2, LRRC59, CSF1R, NOTCH1, CD151, NOTCH4, SLC38A11, LRRC55, PLD3, RHEX, SLC9A1, DPP4, TMEM26, TBXA2R, SLC38A9, TMEM14EP, SLC15A3, SLC38A4, MGAM, BTN2A2, WFS1, TRPV2, G6PC1, BAMBI, ESAM, RNF186, LRP10, CYP4A22, DYSF, ATP2A3, SLC2A2, ECE1, ACSM2B, SPN, SEC61A2, ADGRE5, UGT2A3, TAS2R3, SLC37A4, SCARF1, TAS2R5, BOK, SLC13A2, SLC36A2, TMEM255B, CYP4A11, PLAUR, PTBP2, ITGA5, CLRN3, ST6GALNAC4, SMIM24, MRLN, SLC47A1, UNC93B1, SLC5A12, FURIN, SLC5A10, LRP2, LTC4S, CYP3A5, SLC25A27, DLL4, MARVELD1, CLMN, FAM241A, ANKAR, LRRC8C, UGT1A4, NCAM1, S1PR2, CYYR1, UGT1A6, SLC12A3, EGF, KCNJ13, TIE1, PRAF2, SEMA4C, OR51E2, KCNJ16, MCOLN1, TSPAN14, CD4, FRAS1, INAFM2, TSPAN18, IL2RB, CD248, ATP13A2	865	5406	20472	1.081346994	1	1	0.985507246
CC	GO:0070062~extracellular exosome	extracellular exosome	161	15.63106796	4.58E-12	RIPOR1, TFRC, RAB3D, FOLH1B, PDCD5, PLAT, ICAM1, HID1, STK10, TUBB6, RUSC2, ARHGDIA, PGAP6, CPNE2, ENPP3, PRKACA, EPHB4, TGM2, CUBN, SLC6A19, SPINK1, SLC15A2, HGD, TMEM52B, IGFBP2, RNASE2, HSPG2, UPB1, ACE2, SCNN1G, AZGP1, COL4A2, ADAM15, DAAM2, RAB35, NAAA, MXRA8, FSCN1, RHCG, HPD, ATP6V0D2, SLC27A2, FKBP5, CETP, MIR1290, DDX5, SLC22A5, GSTCD, TWF2, PCDH12, NID1, PLD3, DPP3, ADH6, SLC9A1, DPP4, SLC9A3R2, PKHD1, EFNB1, SCIN, S100A16, ATP6V0A4, NCKAP1L, PCK1, WNT3, LYN, VAT1, MGAM, NIBAN2, JUP, NEBL, ZG16B, GGH, MIR29C, PILRA, LYZ, ARHGAP23, PRRC2A, BST2, EHD2, BHMT, EHD4, GIPC2, ALB, SERPINI2, SLC22A8, HRG, ITM2C, FERMT3, SLC35F6, ROBO4, ECM1, CLIC3, TINAGL1, ARPC1B, DYSF, HBB, SECTM1, ECE1, PYGL, SERPINA6, FTCD, SERPINA5, SPN, CALB1, ADGRE5, CHMP1A, RAC2, SLC13A2, SLC36A2, BHMT2, BGN, MIR21, HBA2, VPS37B, HBA1, RHOF, FGR, H2BC14, GPRC5B, RTN4RL1, CTDSP1, CDHR2, PXDN, CD48, ALDOB, MFGE8, CLRN3, ATP6V1B1, C11ORF54, DDC, RAB1B, FGL2, SEMA3G, AFM, SLC5A12, FURIN, SLC5A10, LRP2, PBLD, CRYZ, RIDA, GNG2, GNA11, GNG7, SLIT2, HNRNPA1, SLC12A3, EGF, F11, BBOX1, GATM, MYO1C, AXL, GSTA2, GSTA1, GALM, CD248, ALDH8A1, TPT1, PLCD1	865	2218	20472	1.717942009	2.53E-09	2.53E-09	2.49E-09
CC	GO:0016020~membrane	membrane	134	13.00970874	0.005104306	RERGL, CNTFR, RIPOR1, PLXND1, TFRC, CSF1, CDH9, SLC8A1, ICAM1, CXCL16, HID1, LIPE, CDH5, CCND1, ARHGDIA, PRKACA, KPNA2, FADS1, PDGFRB, TMOD1, CUBN, IL1R2, USP2, FLT3LG, TAP1, ANK2, ATP1B2, HSPG2, PRLR, GEM, ACE2, COL4A2, COL4A1, SLCO2A1, ORAI1, CLEC4E, PLPP3, ATP6V0D2, PRR11, FKBP5, LRRC59, SEMA7A, DDX5, CD151, GYPC, SDC3, PDGFB, DPP4, EFNB2, GRK2, CASKIN2, INPP5K, NCKAP1L, ST3GAL2, MARK2, MGAM, IQSEC1, TNFSF12, SSC5D, G6PC1, CHERP, ABHD12B, PRRC2A, BST2, EHD4, DCHS1, FXYD5, LRP10, MAP3K11, FERMT3, OGFR, ACVRL1, SLC35F6, CLIC3, SLC2A2, ECE1, TFCP2L1, DOC2B, CX3CL1, PIK3C2B, SERPINA5, SPN, THBD, ADGRE5, BLNK, GNRHR, RAC2, PDE4A, SLC37A4, COLGALT1, BOK, OFD1, SLC13A2, ABCC2, PDE4D, PLA2G4C, HBA2, HBA1, NCOR2, RILPL2, OAS1, OAS2, CD48, PLEKHO1, MFGE8, SMIM24, SLC47A1, RRBP1, FURIN, LRP2, STRN4, GNG2, LRRC8C, NCAM1, SLIT2, HNRNPA1, SLC17A1, SLC17A4, SLC12A3, PRAF2, F11, SPRY4, VEGFC, KCNJ16, MYO9B, MCOLN1, SLC8B1, CD4, MYO1C, ABI3, IL2RB, ATP13A2, TMEM39B, SLC28A2	865	2547	20472	1.245145258	0.940981818	0.201620085	0.198338746
CC	GO:0005615~extracellular space	extracellular space	99	9.611650485	0.032222181	FCN1, FCN3, TFRC, CSF1, PLAT, OLFML2A, ICAM1, CXCL16, ARHGDIA, IL15RA, MIR194-1, CXADR, IGFBP4, IGFBP2, FLT3LG, MIRLET7G, RNASE2, HSPG2, ACE2, AZGP1, COL4A2, ADAM15, COL4A1, MFNG, ADPRH, PLA1A, CETP, SEMA7A, PDGFB, LTBP4, CFP, MST1L, S100A16, S100A12, IGFBP6, WNT3, TGFB1, ZG16B, LRRN2, TNFSF12, MCAM, GGH, MIR29C, ADA2, SSC5D, LYZ, MIR215, BMP2, ALB, SERPINI2, GNRH1, ECM1, FLT1, TINAGL1, CYP4A22, WFDC1, HBB, SECTM1, ADM, LRRC32, SERPINA6, CX3CL1, CTSS, SERPINA5, SPN, THBD, MYDGF, COL10A1, MUC13, SOST, CTSL3P, INSL4, BGN, MIR21, HBA2, HBA1, C1QL3, C1QL1, GPRC5B, RTN4RL1, PXDN, KIT, MFGE8, ENG, FGL2, SEMA3G, AFM, SEMA3F, SLIT2, CBR3, JAM3, EGF, F11, SEMA4C, VEGFC, SEMA4G, MIR421, AXL, TPT1	865	1936	20472	1.210246978	0.999999986	0.742452754	0.730369436
CC	GO:0005730~nucleolus	nucleolus	98	9.514563107	4.22E-07	SNORA6, JPT1, SNORD45B, SNORA4, SCARNA1, SNORD116-23, SNORD116-20, PYCARD, SNORD116-18, SNORD17, SNORD116-15, SNORD116-14, SNORD16, SNORD116-16, SNORD98, SNORA32, IER5, SNORD94, SNORD58C, LDOC1, SNORD116-29, SNORD116-26, SNORD102, SNORD116-25, SNORD101, SNORD104, SNORA28, SNORA25, SNORA26, SNORD89, SRSF5, SNORA24, SNORA21, TP53, SNORD82, SNORD59B, DDX5, SNORA36B, SNORD3C, SNORD3D, MRO, SNORD59A, RRP7A, SNORA5A, S100A16, KCNQ1OT1, SNORD50B, SNORD30, SNORA53, SNORD36C, SURF2, IQSEC1, SCARNA9, SNORD28, SNORD29, SNORD123, SCARNA6, SNORA49, SCARNA7, NOX4, SNORA48, SNORD5, SNORA41, SNORA81, HSPB6, KRI1, H1-10, ENC1, SNORA79, SNORA75, PRMT6, SNORA72, SNORD4B, SNORA70F, GPRC5B, SNORD46, SNORD47, PWARSN, SNORD80, SCARNA10, SNORD116-1, SCARNA17, SNORD114-16, SNORD114-19, TAF1D, SNORD114-13, SNORD79, SNORA12, SNORD76, SNORA11, SNORD71, SNORD32A, PML, MYO1C, TCIM, TAOK2, SNORD83B, SNORD67	865	1378	20472	1.683143032	2.34E-04	6.04E-05	5.94E-05
CC	GO:0005887~integral component of plasma membrane	integral component of plasma membrane	96	9.32038835	5.51E-05	PCDHB18P, ACVRL1, FLT1, SIGLEC9, PLXND1, TFRC, FLT4, GPR65, SLC2A2, GRIK1, LRRC32, SLC8A1, ICAM1, SPN, THBD, GJA3, ADGRE5, IYD, GJA5, BOC, GJA4, KDR, PGAP6, GNRHR, SLC16A9, CD34, EPHB4, PDGFRB, SLC13A2, SLC6A19, FCER1G, SLC15A2, ABCC2, CXADR, KCNH6, PLAUR, CYBB, TAP1, PCDHA12, SCNN1G, TYROBP, GJD3, SLC7A7, STIM1, SLC7A9, SLCO2A1, KIT, APLNR, ORAI1, RHCG, PLPP3, CSF1R, RAMP2, SEMA7A, CD151, GYPC, NOTCH4, PTGER3, SEMA3G, SEMA3F, PCDH12, LRRC55, PCDH17, SLC9A1, EFNB2, EFNB1, TBXA2R, LRRC8C, PLXNA2, S1PR3, NCKAP1L, SLC17A1, S1PR4, TRPM3, SLC38A4, SLC17A4, JAM3, SLC12A3, TIE1, TNFSF12, SEMA4C, TRPV2, GPR52, SLC16A12, LAPTM5, GPR4, SEMA4G, MCOLN1, CD4, TSPAN14, SLCO3A1, SYT11, AXL, TSPAN18, IL2RB, SLC28A2	865	1508	20472	1.506655832	0.030019608	0.005079764	0.004997091
CC	GO:0005789~endoplasmic reticulum membrane	endoplasmic reticulum membrane	59	5.72815534	0.022867075	NRROS, GIMAP1, CYP4A22, ATP2A3, SEC61A2, CYP4Z1, CYP26B1, EVA1A, RAC2, SLC37A4, KPNA2, FADS1, BOK, IL15RA, SLC36A2, RSAD2, PLA2G4C, CYP4A11, PLAUR, CYBB, TAP1, SHISA3, TMEM174, SELENON, STIM1, TBC1D20, KDELR3, PLPP3, HPD, SLC27A2, LRRC59, GRAMD1A, NOTCH1, UNC93B1, RAB1B, NOTCH4, LTC4S, CYP3A5, PLD3, SLC9A1, DDN, HSD11B2, CYP2B6, AGMO, RDH10, LRRC8C, UGT1A4, UGT1A6, WFS1, CYP4F2, FMO1, CYP8B1, G6PC1, ABHD12B, CD4, STING1, NOX4, ANKS4B, RNF186	865	1052	20472	1.327334667	0.999997218	0.586013593	0.576476301
CC	GO:0009986~cell surface	cell surface	56	5.436893204	4.37E-07	ACVRL1, NRROS, TFRC, PLAT, LRRC32, ANTXR1, CX3CL1, ICAM1, SPN, THBD, CDH5, ADGRA2, PDGFRB, IL15RA, FCER1G, ABCC2, PLAUR, BGN, FLT3LG, EMP2, ANK3, PRLR, AJAP1, ACE2, GPRC5B, TYROBP, GJD3, ADAM15, RTN4RL1, PXDN, MXRA8, ITGA8, ITGA5, HCST, ENG, CSF1R, RAMP2, CD151, NOTCH1, NOTCH4, SDC3, PDGFB, FURIN, SLC9A1, DPP4, NCAM1, SLIT2, TGFB1, TRPV2, BST2, LRFN3, BMP2, TSPAN14, AXL, IL2RB, HRG	865	638	20472	2.077358798	2.41E-04	6.04E-05	5.94E-05
CC	GO:0016324~apical plasma membrane	apical plasma membrane	43	4.174757282	8.26E-09	CNTFR, SLC47A1, NOTCH1, SLC22A5, SLC5A12, SLC2A2, LRP2, SLC9A1, PKHD1, SLC9A3R2, DPP4, MUC13, ATP6V0A4, ENPP3, SLC17A1, CD34, SLC17A4, PDGFRB, CUBN, SLC12A3, MGAM, SLC6A19, ABCC2, SLC15A2, CYP4F2, PDE4D, IGFBP2, CYP4A11, EMP2, ANK2, ATP1B2, AJAP1, BST2, SCNN1G, ACE2, SLC9A4, SLC7A9, CDHR2, NOX4, RHCG, SLC22A8, ATP6V0D2, ATP6V1B1	865	374	20472	2.721078174	4.57E-06	2.28E-06	2.25E-06
BP	GO:0006396~RNA processing	RNA processing	75	7.281553398	7.18E-18	SNORA6, SNORD45B, SNORA81, SNORA4, SCARNA1, SNORD116-23, SNORD116-20, SNORD116-18, SNORD17, SNORD116-15, SNORD16, SNORD116-14, SNORD116-16, SNORA79, SNORD98, CCNL1, SNORA32, SNORD94, SNORA75, SNORA72, SNORD58C, SNORD4B, SNORD116-29, SNORA70F, SNORD102, SNORD116-26, SNORD101, SNORD116-25, SNORD104, SNORD46, SNORD47, SNORA28, SNORA25, SNORA26, SNORD89, SNORA24, SNORA21, SNORD82, PWARSN, SNORD80, SNORD59B, SNORA36B, SCARNA10, SNORD3C, SNORD3D, SCARNA17, SNORD116-1, SNORD59A, SNORD114-16, SNORA5A, SNORD114-19, SNORD114-13, SNORD79, SNORD50B, SNORA12, SNORD76, SNORA11, SNORD30, SNORD71, SNORA53, SNORD36C, SNORD32A, CHERP, SCARNA9, SNORD28, SNORD29, SNORD123, SCARNA6, SNORA49, SCARNA7, SNORD83B, SNORD67, SNORA48, SNORD5, SNORA41	826	569	19256	3.072805185	2.68E-14	2.68E-14	2.66E-14
BP	GO:0007165~signal transduction	signal transduction	75	7.281553398	0.004046902	RERGL, ACVRL1, CNTFR, ECM1, CLIC3, RAPH1, SECTM1, ADM, OLFML2A, NRGN, CXCL16, ELK3, SPN, PYCARD, SYDE1, GRB14, RASSF3, RGS1, RAC2, PDE4A, CD34, INSL4, CDKL2, PDGFRB, IGFBP4, PDE4D, IGFBP2, PPP2R5B, PLAUR, FLT3LG, ARAP3, ANK2, ANK3, CSNK1E, GEM, ARHGAP10, TYROBP, RASA3, KIT, RAPGEF1, PLPP3, RIN2, CDC42SE1, CSF1R, LRRC59, NEDD9, GATA3, RASIP1, DLL4, GRK2, RASD1, HLX, INPP5D, GNA11, IGFBP6, RALGDS, SH2B3, LYN, SLC12A3, LRRN2, TIE1, TNFSF12, VEGFC, ADA2, LILRB1, PILRA, ARHGAP23, CD4, AXL, IL2RB, CDK2, ZYX, GNRH1, PDE7A, OGT	826	1267	19256	1.379973283	0.999999727	0.335173421	0.333464729
BP	GO:0045944~positive regulation of transcription from RNA polymerase II promoter	positive regulation of transcription from RNA polymerase II promoter	62	6.019417476	0.093786093	ACVRL1, CSRNP1, RARG, HNF4G, TFCP2L1, CX3CL1, ELK3, MYDGF, HHEX, SOX17, SOX18, HNF4A, IER5, TET2, PPP2R5B, TOX2, DMTF1, ELF4, IRF1, ITGA8, HCLS1, LMX1B, ARHGEF2, TP53, HOXB5, ENG, KMT2D, HDAC5, FOXC2, ASCL3, NFIX, NOTCH1, CEBPD, GATA5, GATA3, RELA, SLC9A1, DDN, PLAC8, HOXC4, PPARGC1A, TGFB1, JUP, DMRT2, ZBTB16, EAF2, NFATC2, NFATC1, ESRRG, LILRB1, NR1D1, MEIS2, TBX3, KLF2, DRAP1, SKI, BMP2, MAFB, STING1, BCL3, HOXD3, OGT	826	1201	19256	1.203468457	1	1	0.995169082
BP	GO:0000122~negative regulation of transcription from RNA polymerase II promoter	negative regulation of transcription from RNA polymerase II promoter	54	5.242718447	0.039634532	RARG, NRARP, TFCP2L1, ELK3, HHEX, CCND1, SOX18, ZNF366, AASS, PRMT6, USP2, NCOR2, HCLS1, TP53, ZNF596, ENG, HDAC5, FOXC2, ASCL3, DDX5, NFIX, NOTCH1, NOTCH4, GATA5, FOXK1, GATA3, RELA, HDAC7, DLL4, MNT, NFIL3, NRIP2, CBX6, TGFB1, ZNF141, WFS1, GADD45A, ZBTB16, NFATC2, NR1D1, MEIS2, TBX3, KLF2, DRAP1, SKI, H1-4, BMP2, MAFB, BCL6B, ID1, CDK2, SNAI2, OGT, MXD4	826	967	19256	1.301827123	1	0.910292909	0.905652296
BP	GO:0045893~positive regulation of transcription, DNA-templated	positive regulation of transcription, DNA-templated	44	4.27184466	0.016261092	ACVRL1, FOXC2, NOTCH1, TGFB1I1, NOTCH4, PDGFB, FOXK1, GATA3, RELA, CAND2, LYL1, HHEX, SOX17, NFIL3, SOX18, HNF4A, INPP5K, SOST, SOX7, PPARGC1A, TGFB1, NIBAN2, DTX3L, EGF, ZBTB16, EAF2, NFATC2, NFATC1, ESRRG, NR1D1, TBX3, PML, KLF2, BMP2, CD4, MAFB, BAMBI, ELF4, IRF1, MAK, BCL3, CDK2, OGT, TP53	826	716	19256	1.432602432	1	0.606050902	0.602961295
BP	GO:0008284~positive regulation of cell proliferation	positive regulation of cell proliferation	43	4.174757282	2.11E-04	SLC35F6, KMT2D, CSF1R, CNTFR, RARG, MIR1290, FLT1, NOTCH1, CSF1, FLT4, PDGFB, ADM, RELA, CX3CL1, PKHD1, SLC25A27, DPP4, EFNB2, PLAC8, ESM1, HLX, ZNF703, KDR, RAC2, S1PR3, S1PR2, LYN, PDGFRB, TGFB1, EGF, VEGFC, FLT3LG, MIR21, EMP2, PRLR, MEIS2, TBX3, BAMBI, KIT, CDK2, HCLS1, CD248, FXN	826	549	19256	1.825921663	0.543940016	0.05233655	0.052069741
BP	GO:0008285~negative regulation of cell proliferation	negative regulation of cell proliferation	40	3.883495146	3.87E-05	ACVRL1, CSF1R, RARG, NOTCH1, TGFB1I1, PDCD5, ADM, GATA3, DLL4, CDH5, CYP27B1, MNT, SCIN, ADAMTS1, CLMN, HNF4A, LMNA, IGFBP6, TP53I11, SOX7, SH2B3, LYN, TGFB1, NIBAN2, NOS3, DUSP1, ZBTB16, MIR29C, MIR21, LDOC1, PML, CHERP, SKI, BMP2, AZGP1, IRF1, NOX4, GNRH1, HRG, TP53	826	459	19256	2.031577226	0.134435511	0.01443706	0.014363461
BP	GO:0010628~positive regulation of gene expression	positive regulation of gene expression	40	3.883495146	4.05E-04	RAMP2, RARG, NOTCH1, CSF1, TFRC, PDCD5, PDGFB, GATA5, MIR506, FTX, LRRC32, RELA, PPM1F, DLL4, CDH5, CYP26B1, SOX17, NFIL3, KCNQ1OT1, LMNA, BLNK, PPARGC1A, CD34, WNT3, TGFB1, EGF, NOS3, NFATC2, MIR21, ANK2, LILRB1, ANK3, BMP2, TYROBP, ID1, PLP1, ATP13A2, HOXD3, TP53, ENG	826	513	19256	1.817726992	0.779400952	0.075555103	0.075169928
BP	GO:0007155~cell adhesion	cell adhesion	40	3.883495146	0.001847811	PCDHB18P, CD151, SIGLEC9, TGFB1I1, NEDD9, PCDH12, RND3, CX3CL1, PCDH17, ICAM1, DPP4, EFNB2, EFNB1, ADGRE5, BOC, NCAM1, SCARF1, CD34, EPHB4, JAM3, TNFRSF12A, JUP, CNTN5, LRRN2, MCAM, SIGLEC10, EMP2, PCDHA12, AJAP1, CD4, AZGP1, CLDN8, PXDN, ADAM12, ITGA8, MXRA8, ITGA5, MFGE8, JCAD, ENG	826	557	19256	1.67413635	0.998985301	0.237475604	0.236264969
BP	GO:0001525~angiogenesis	angiogenesis	38	3.689320388	5.42E-11	ACVRL1, ROBO4, RAMP2, ECM1, FLT1, PLXND1, FLT4, RASIP1, ELK3, DLL4, MYDGF, ESM1, SOX17, SOX18, GJA5, KDR, EPHB4, JAM3, PDGFRB, TNFRSF12A, EGF, NOS3, UNC5B, MCAM, TIE1, TNFSF12, HSPG2, FMNL3, COL4A2, ADAM15, ID1, PXDN, APLNR, ITGA5, PLCD3, HRG, MFGE8, ENG	826	252	19256	3.515354164	2.02E-07	1.01E-07	1.00E-07

Category	Term	Count	%	PValue	Genes	List Total	Pop Hits	Pop Total	Fold Enrichment	Bonferroni	Benjamini	FDR
KEGG_PATHWAY	hsa04933:AGE-RAGE signaling pathway in diabetic complications	14	1.359223301	7.79E-04	TGFB1, NOS3, VEGFC, CYBB, NFATC1, RELA, ICAM1, THBD, COL4A2, CCND1, COL4A1, NOX4, PLCD3, PLCD1	385	100	8156	2.965818182	0.210420964	0.221815464	0.220351335
KEGG_PATHWAY	hsa05418:Fluid shear stress and atherosclerosis	16	1.553398058	0.002205696	NOS3, DUSP1, IL1R2, PDGFB, PLAT, RELA, KLF2, ICAM1, CDH5, THBD, GSTA2, GSTA1, KDR, RAC2, ARHGEF2, TP53	385	139	8156	2.43849388	0.487812263	0.221815464	0.220351335
KEGG_PATHWAY	hsa04151:PI3K-Akt signaling pathway	30	2.912621359	0.002467508	CSF1R, FLT1, CSF1, FLT4, PDGFB, RELA, GNG2, CCND1, GNG7, KDR, THEM4, PCK1, PCK2, PDGFRB, EGF, NOS3, PPP2R5B, VEGFC, FLT3LG, G6PC1, PRLR, COL4A2, COL4A1, DDIT4, KIT, IL2RB, CDK2, ITGA8, ITGA5, TP53	385	354	8156	1.795289456	0.526961647	0.221815464	0.220351335
KEGG_PATHWAY	hsa04010:MAPK signaling pathway	26	2.524271845	0.002928257	CSF1R, FLT1, CSF1, FLT4, PDGFB, RELA, DUSP10, KDR, RAC2, PRKACA, PDGFRB, MAP4K2, TGFB1, EGF, GADD45A, DUSP1, PLA2G4C, VEGFC, FLT3LG, NFATC1, DUSP7, TAOK2, KIT, PTPN7, TP53, MAP3K11	385	294	8156	1.873451718	0.588753901	0.221815464	0.220351335
KEGG_PATHWAY	hsa00982:Drug metabolism - cytochrome P450	10	0.970873786	0.006360022	CYP2B6, MAOA, GSTA2, GSTA1, UGT1A4, FMO1, UGT2A3, CYP3A5, ADH6, UGT1A6	385	72	8156	2.942279942	0.855321438	0.38541731	0.382873301
KEGG_PATHWAY	hsa04974:Protein digestion and absorption	12	1.165048544	0.008886575	DPP4, ACE2, SLC6A19, SLC7A7, SLC36A2, COL4A2, SLC7A9, COL4A1, KCNJ13, COL10A1, ATP1B2, SLC8A1	385	103	8156	2.468087253	0.93310745	0.44877203	0.445809839
KEGG_PATHWAY	hsa04371:Apelin signaling pathway	14	1.359223301	0.013713774	HDAC5, NOS3, PLAT, SLC8A1, RYR3, KLF2, SLC9A1, LIPE, GNG2, CCND1, GNG7, APLNR, PRKACA, PPARGC1A	385	139	8156	2.133682145	0.984763007	0.564922358	0.561193498
KEGG_PATHWAY	hsa04014:Ras signaling pathway	20	1.941747573	0.014915442	PDGFRB, CSF1R, FLT1, CSF1, EGF, FLT4, PLA2G4C, PDGFB, VEGFC, FLT3LG, RELA, GNG2, RASA3, GNG7, KIT, KDR, RAC2, PRKACA, RALGDS, PLA1A	385	235	8156	1.802928986	0.989468895	0.564922358	0.561193498
KEGG_PATHWAY	hsa04020:Calcium signaling pathway	20	1.941747573	0.018259438	PDGFRB, FLT1, NOS3, EGF, FLT4, PTGER3, PDGFB, ATP2A3, VEGFC, MCOLN1, SLC8A1, RYR3, STIM1, TBXA2R, GNA11, KDR, ORAI1, PLCD3, PRKACA, PLCD1	385	240	8156	1.765367965	0.996241533	0.6147344	0.610676747
KEGG_PATHWAY	hsa05200:Pathways in cancer	36	3.495145631	0.026122046	CSF1R, NOTCH1, FLT4, NOTCH4, PTGER3, PDGFB, RELA, DLL4, GNG2, CCND1, GNA11, GNG7, RAC2, PRKACA, RALGDS, WNT3, PDGFRB, IL15RA, TCF7L1, TGFB1, JUP, EGF, GADD45A, ZBTB16, VEGFC, FLT3LG, PML, BMP2, COL4A2, COL4A1, GSTA2, KIT, IL2RB, CDK2, GSTA1, TP53	385	531	8156	1.436231565	0.999671244	0.672708158	0.66826784
KEGG_PATHWAY	hsa05110:Vibrio cholerae infection	7	0.67961165	0.028939883	SEC61A2, ATP6V0A4, KDELR3, ATP6V1G3, PRKACA, ATP6V0D2, ATP6V1B1	385	50	8156	2.965818182	0.999863361	0.672708158	0.66826784
KEGG_PATHWAY	hsa00980:Metabolism of xenobiotics by cytochrome P450	9	0.873786408	0.029705771	CYP2B6, GSTA2, GSTA1, UGT1A4, UGT2A3, CYP3A5, ADH6, UGT1A6, CBR3	385	78	8156	2.444355644	0.999892417	0.672708158	0.66826784
KEGG_PATHWAY	hsa00360:Phenylalanine metabolism	4	0.388349515	0.036730917	DDC, MAOA, PAH, HPD	385	16	8156	5.296103896	0.9999881	0.672708158	0.66826784
KEGG_PATHWAY	hsa05221:Acute myeloid leukemia	8	0.776699029	0.037291671	CSF1R, TCF7L1, JUP, CCND1, ZBTB16, KIT, RELA, PML	385	67	8156	2.529482458	0.999990025	0.672708158	0.66826784
KEGG_PATHWAY	hsa00260:Glycine, serine and threonine metabolism	6	0.582524272	0.03828908	GATM, BHMT, MAOA, AGXT2, GLDC, PIPOX	385	40	8156	3.177662338	0.999992714	0.672708158	0.66826784
KEGG_PATHWAY	hsa05215:Prostate cancer	10	0.970873786	0.038501069	PDGFRB, TCF7L1, CCND1, EGF, IL1R2, CDK2, PDGFB, PLAT, TP53, RELA	385	97	8156	2.18396037	0.999993185	0.672708158	0.66826784
KEGG_PATHWAY	hsa05165:Human papillomavirus infection	24	2.330097087	0.039096874	PDGFRB, TCF7L1, NOTCH1, EGF, NOTCH4, PPP2R5B, ISG15, RFNG, RELA, COL4A2, CCND1, COL4A1, IRF1, MFNG, CDK2, ITGA8, ATP6V0A4, ITGA5, ATP6V1G3, PRKACA, TP53, ATP6V0D2, WNT3, ATP6V1B1	385	331	8156	1.536030133	0.999994352	0.672708158	0.66826784
KEGG_PATHWAY	hsa00830:Retinol metabolism	8	0.776699029	0.039962861	CYP26B1, CYP2B6, RDH10, UGT1A4, UGT2A3, CYP3A5, ADH6, UGT1A6	385	68	8156	2.492284186	0.999995702	0.672708158	0.66826784
KEGG_PATHWAY	hsa04742:Taste transduction	9	0.873786408	0.048811211	SCNN1G, TAS2R31, TAS2R20, TAS2R10, TAS2R14, PRKACA, TAS2R3, SCN3A, TAS2R5	385	86	8156	2.216973724	0.99999974	0.770442293	0.765356865