{"text_format":"3","workbook":"xls","n_sheets":7,"sheets":["Stable1","Stable2","Stable3","Stable4","Stable5","Stable6","Stable7"],"not_rendered":{"external_links":1,"defined_names":1},"read":"whole","date_system":"1900","formulas":"cached_only"}

{"sheet":"Stable1","index":0,"n_rows":37,"n_cols":3,"rows_kept":37,"flags":["formulas_cached_only"]}
["Supplementary Table 1. SLC31A1 genetic alteration types in TCGA datasets from cBioportal."]
["Cancer Study","Alteration Frequency","Alteration Type"]
["Uterine Corpus Endometrial Carcinoma (TCGA, PanCancer Atlas)",1.13421550094517,"amplification"]
["Uterine Corpus Endometrial Carcinoma (TCGA, PanCancer Atlas)",1.32325141776937,"mutated"]
["Adrenocortical Carcinoma (TCGA, PanCancer Atlas)",2.19780219780219,"amplification"]
["Bladder Urothelial Carcinoma (TCGA, PanCancer Atlas)",0.72992700729927,"homdel"]
["Bladder Urothelial Carcinoma (TCGA, PanCancer Atlas)",0.24330900243309,"amplification"]
["Bladder Urothelial Carcinoma (TCGA, PanCancer Atlas)",0.24330900243309,"mutated"]
["Prostate Adenocarcinoma (TCGA, PanCancer Atlas)",1.01214574898785,"amplification"]
["Prostate Adenocarcinoma (TCGA, PanCancer Atlas)",0.20242914979757,"mutated"]
["Sarcoma (TCGA, PanCancer Atlas)",1.17647058823529,"amplification"]
["Kidney Renal Papillary Cell Carcinoma (TCGA, PanCancer Atlas)",0.353356890459363,"homdel"]
["Kidney Renal Papillary Cell Carcinoma (TCGA, PanCancer Atlas)",0.353356890459363,"amplification"]
["Kidney Renal Papillary Cell Carcinoma (TCGA, PanCancer Atlas)",0.353356890459363,"mutated"]
["Skin Cutaneous Melanoma (TCGA, PanCancer Atlas)",0.9009009009009,"mutated"]
["Lung Squamous Cell Carcinoma (TCGA, PanCancer Atlas)",0.205338809034907,"homdel"]
["Lung Squamous Cell Carcinoma (TCGA, PanCancer Atlas)",0.616016427104722,"mutated"]
["Thyroid Carcinoma (TCGA, PanCancer Atlas)",0.8,"homdel"]
["Head and Neck Squamous Cell Carcinoma (TCGA, PanCancer Atlas)",0.764818355640535,"amplification"]
["Breast Invasive Carcinoma (TCGA, PanCancer Atlas)",0.092250922509225,"multiple"]
["Breast Invasive Carcinoma (TCGA, PanCancer Atlas)",0.3690036900369,"amplification"]
["Breast Invasive Carcinoma (TCGA, PanCancer Atlas)",0.276752767527675,"mutated"]
["Ovarian Serous Cystadenocarcinoma (TCGA, PanCancer Atlas)",0.171232876712328,"homdel"]
["Ovarian Serous Cystadenocarcinoma (TCGA, PanCancer Atlas)",0.342465753424657,"amplification"]
["Ovarian Serous Cystadenocarcinoma (TCGA, PanCancer Atlas)",0.171232876712328,"mutated"]
["Stomach Adenocarcinoma (TCGA, PanCancer Atlas)",0.227272727272727,"homdel"]
["Stomach Adenocarcinoma (TCGA, PanCancer Atlas)",0.227272727272727,"amplification"]
["Stomach Adenocarcinoma (TCGA, PanCancer Atlas)",0.227272727272727,"mutated"]
["Glioblastoma Multiforme (TCGA, PanCancer Atlas)",0.506756756756756,"amplification"]
["Glioblastoma Multiforme (TCGA, PanCancer Atlas)",0.168918918918918,"mutated"]
["Colorectal Adenocarcinoma (TCGA, PanCancer Atlas)",0.168350168350168,"amplification"]
["Colorectal Adenocarcinoma (TCGA, PanCancer Atlas)",0.505050505050505,"mutated"]
["Esophageal Adenocarcinoma (TCGA, PanCancer Atlas)",0.549450549450549,"amplification"]
["Liver Hepatocellular Carcinoma (TCGA, PanCancer Atlas)",0.53763440860215,"amplification"]
["Lung Adenocarcinoma (TCGA, PanCancer Atlas)",0.353356890459363,"homdel"]
["Lung Adenocarcinoma (TCGA, PanCancer Atlas)",0.176678445229681,"amplification"]
["Brain Lower Grade Glioma (TCGA, PanCancer Atlas)",0.389105058365758,"amplification"]

{"sheet":"Stable2","index":1,"n_rows":31,"n_cols":12,"rows_kept":31,"flags":["formulas_cached_only"]}
["Supplementary Table 2. SLC31A1 genetic mutations summary in TCGA datasets from cBioportal."]
["Study of Origin","Sample ID","Cancer Type","Protein Change","Functional Impact","Mutation Type","Variant Type","Copy ","Ref","Var","HGVSg","HGVSc"]
["Breast Invasive Carcinoma (TCGA, PanCancer Atlas)","TCGA-D8-A1XQ-01","Breast Cancer","SNX30-SLC31A1","SIFT: NA;Polyphen-2: NA","fusion","FUSION","DeepDel"]
["Ovarian Serous Cystadenocarcinoma (TCGA, PanCancer Atlas)","TCGA-24-1844-01","Ovarian Epithelial Tumor","M81V","SIFT: impact: tolerated, score: 0.41;Polyphen-2: impact: benign, score: 0.006","Missense_Mutation","SNP","Gain","A","G","9:g.116021012A>G","ENST00000374212.4:c.241A>G"]
["Glioblastoma Multiforme (TCGA, PanCancer Atlas)","TCGA-19-5956-01","Glioblastoma","S105Y","SIFT: impact: deleterious, score: 0;Polyphen-2: impact: probably_damaging, score: 0.996","Missense_Mutation","SNP","Diploid","C","A","9:g.116021085C>A","ENST00000374212.4:c.314C>A"]
["Lung Squamous Cell Carcinoma (TCGA, PanCancer Atlas)","TCGA-85-6561-01","Non-Small Cell Lung Cancer","L149I","SIFT: NA;Polyphen-2: NA","Missense_Mutation","SNP","Diploid","C","A","9:g.116022625C>A","ENST00000374212.4:c.445C>A"]
["Lung Squamous Cell Carcinoma (TCGA, PanCancer Atlas)","TCGA-77-8133-01","Non-Small Cell Lung Cancer","S32F","SIFT: impact: deleterious, score: 0.01;Polyphen-2: impact: possibly_damaging, score: 0.621","Missense_Mutation","SNP","Gain","C","T","9:g.116018523C>T","ENST00000374212.4:c.95C>T"]
["Lung Squamous Cell Carcinoma (TCGA, PanCancer Atlas)","TCGA-85-A513-01","Non-Small Cell Lung Cancer","A165T","SIFT: NA;Polyphen-2: NA","Missense_Mutation","SNP","ShallowDel","G","A","9:g.116022673G>A","ENST00000374212.4:c.493G>A"]
["Bladder Urothelial Carcinoma (TCGA, PanCancer Atlas)","TCGA-XF-A8HE-01","Bladder Cancer","M9I","SIFT: impact: tolerated_low_confidence, score: 0.07;Polyphen-2: impact: benign, score: 0.039","Missense_Mutation","SNP","Diploid","G","T","9:g.116018455G>T","ENST00000374212.4:c.27G>T"]
["Prostate Adenocarcinoma (TCGA, PanCancer Atlas)","TCGA-EJ-A7NN-01","Prostate Cancer","H3L","SIFT: impact: deleterious, score: 0;Polyphen-2: impact: benign, score: 0.058","Missense_Mutation","SNP",null,"A","T","9:g.116018436A>T","ENST00000374212.4:c.8A>T"]
["Uterine Corpus Endometrial Carcinoma (TCGA, PanCancer Atlas)","TCGA-AP-A0LM-01","Endometrial Cancer","R90*","SIFT: NA;Polyphen-2: NA","Nonsense_Mutation","SNP","Diploid","C","T","9:g.116021039C>T","ENST00000374212.4:c.268C>T"]
["Uterine Corpus Endometrial Carcinoma (TCGA, PanCancer Atlas)","TCGA-AP-A0LM-01","Endometrial Cancer","S105Y","SIFT: impact: deleterious, score: 0;Polyphen-2: impact: probably_damaging, score: 0.996","Missense_Mutation","SNP","Diploid","C","A","9:g.116021085C>A","ENST00000374212.4:c.314C>A"]
["Uterine Corpus Endometrial Carcinoma (TCGA, PanCancer Atlas)","TCGA-AX-A0J0-01","Endometrial Cancer","L78V","SIFT: impact: tolerated, score: 0.08;Polyphen-2: impact: possibly_damaging, score: 0.754","Missense_Mutation","SNP","Diploid","T","G","9:g.116021003T>G","ENST00000374212.4:c.232T>G"]
["Uterine Corpus Endometrial Carcinoma (TCGA, PanCancer Atlas)","TCGA-A5-A0G1-01","Endometrial Cancer","A66D","SIFT: impact: deleterious, score: 0.01;Polyphen-2: impact: possibly_damaging, score: 0.856","Missense_Mutation","SNP","Diploid","C","A","9:g.116019460C>A","ENST00000374212.4:c.197C>A"]
["Uterine Corpus Endometrial Carcinoma (TCGA, PanCancer Atlas)","TCGA-A5-A0G2-01","Endometrial Cancer","V137M","SIFT: NA;Polyphen-2: NA","Missense_Mutation","SNP","Diploid","G","A","9:g.116022589G>A","ENST00000374212.4:c.409G>A"]
["Uterine Corpus Endometrial Carcinoma (TCGA, PanCancer Atlas)","TCGA-AX-A06F-01","Endometrial Cancer","L94M","SIFT: impact: deleterious, score: 0.01;Polyphen-2: impact: probably_damaging, score: 0.99","Missense_Mutation","SNP","Diploid","C","A","9:g.116021051C>A","ENST00000374212.4:c.280C>A"]
["Uterine Corpus Endometrial Carcinoma (TCGA, PanCancer Atlas)","TCGA-AX-A2HD-01","Endometrial Cancer","M1?","SIFT: impact: deleterious, score: 0.02;Polyphen-2: impact: benign, score: 0.003","Translation_Start_Site","SNP","Diploid","A","G","9:g.116018429A>G","ENST00000374212.4:c.1A>G"]
["Uterine Corpus Endometrial Carcinoma (TCGA, PanCancer Atlas)","TCGA-AX-A2HD-01","Endometrial Cancer","S32Y","SIFT: impact: deleterious, score: 0.01;Polyphen-2: impact: possibly_damaging, score: 0.77","Missense_Mutation","SNP","Diploid","C","A","9:g.116018523C>A","ENST00000374212.4:c.95C>A"]
["Uterine Corpus Endometrial Carcinoma (TCGA, PanCancer Atlas)","TCGA-B5-A3FA-01","Endometrial Cancer","X124_splice","SIFT: NA;Polyphen-2: NA","Splice_Region","SNP","Diploid","G","A","9:g.116022552G>A","ENST00000374212.4:c.372G>A"]
["Skin Cutaneous Melanoma (TCGA, PanCancer Atlas)","TCGA-EE-A3JD-06","Melanoma","P107L","SIFT: impact: deleterious, score: 0.01;Polyphen-2: impact: probably_damaging, score: 0.914","Missense_Mutation","SNP","Diploid","C","T","9:g.116021091C>T","ENST00000374212.4:c.320C>T"]
["Skin Cutaneous Melanoma (TCGA, PanCancer Atlas)","TCGA-FW-A3R5-06","Melanoma","S14F","SIFT: impact: tolerated, score: 0.7;Polyphen-2: impact: benign, score: 0.003","Missense_Mutation","SNP","ShallowDel","C","T","9:g.116018469C>T","ENST00000374212.4:c.41C>T"]
["Skin Cutaneous Melanoma (TCGA, PanCancer Atlas)","TCGA-D3-A2JC-06","Melanoma","H5N","SIFT: impact: tolerated, score: 0.16;Polyphen-2: impact: benign, score: 0.058","Missense_Mutation","SNP","Diploid","C","A","9:g.116018441C>A","ENST00000374212.4:c.13C>A"]
["Skin Cutaneous Melanoma (TCGA, PanCancer Atlas)","TCGA-D3-A2JP-06","Melanoma","A89S","SIFT: impact: tolerated, score: 0.39;Polyphen-2: impact: benign, score: 0.056","Missense_Mutation","SNP","ShallowDel","G","T","9:g.116021036G>T","ENST00000374212.4:c.265G>T"]
["Stomach Adenocarcinoma (TCGA, PanCancer Atlas)","TCGA-VQ-A8P2-01","Esophagogastric Cancer","T17I","SIFT: impact: deleterious, score: 0.02;Polyphen-2: impact: benign, score: 0.031","Missense_Mutation","SNP","Diploid","C","T","9:g.116018478C>T","ENST00000374212.4:c.50C>T"]
["Breast Invasive Carcinoma (TCGA, PanCancer Atlas)","TCGA-B6-A0I8-01","Breast Cancer","H120Q","SIFT: impact: tolerated, score: 0.09;Polyphen-2: impact: benign, score: 0.219","Missense_Mutation","SNP",null,"C","G","9:g.116021131C>G","ENST00000374212.4:c.360C>G"]
["Breast Invasive Carcinoma (TCGA, PanCancer Atlas)","TCGA-A8-A092-01","Breast Cancer","S30L","SIFT: impact: deleterious, score: 0.05;Polyphen-2: impact: benign, score: 0.276","Missense_Mutation","SNP","Diploid","C","T","9:g.116018517C>T","ENST00000374212.4:c.89C>T"]
["Breast Invasive Carcinoma (TCGA, PanCancer Atlas)","TCGA-D8-A27V-01","Breast Cancer","T136Qfs*10","SIFT: NA;Polyphen-2: NA","Frame_Shift_Del","DEL","Gain","A","-","9:g.116022584del","ENST00000374212.4:c.406del"]
["Colorectal Adenocarcinoma (TCGA, PanCancer Atlas)","TCGA-AG-A002-01","Colorectal Cancer","R102C","SIFT: impact: deleterious, score: 0.02;Polyphen-2: impact: probably_damaging, score: 0.987","Missense_Mutation","SNP","Diploid","C","T","9:g.116021075C>T","ENST00000374212.4:c.304C>T"]
["Colorectal Adenocarcinoma (TCGA, PanCancer Atlas)","TCGA-F5-6814-01","Colorectal Cancer","F73S","SIFT: impact: tolerated, score: 0.21;Polyphen-2: impact: possibly_damaging, score: 0.824","Missense_Mutation","SNP","Diploid","T","C","9:g.116020989T>C","ENST00000374212.4:c.218T>C"]
["Colorectal Adenocarcinoma (TCGA, PanCancer Atlas)","TCGA-AG-A00Y-01","Colorectal Cancer","G60D","SIFT: impact: tolerated, score: 0.06;Polyphen-2: impact: probably_damaging, score: 0.961","Missense_Mutation","SNP","Diploid","G","A","9:g.116019442G>A","ENST00000374212.4:c.179G>A"]
["Kidney Renal Papillary Cell Carcinoma (TCGA, PanCancer Atlas)","TCGA-DW-7838-01","Renal Non-Clear Cell Carcinoma","N15Qfs*38","SIFT: NA;Polyphen-2: NA","Frame_Shift_Ins","INS","Diploid","-","C","9:g.116018468_116018469insC","ENST00000374212.4:c.42dup"]

{"sheet":"Stable3","index":2,"n_rows":102,"n_cols":3,"rows_kept":102,"flags":["formulas_cached_only"]}
["Supplementary Table 3.Top 100 genes with similar expression pattern toSLC3A1 gene from all tumor types of TCGA datasets by GEPIA2."]
["Gene Symbol","Gene ID","PCC"]
["SURF4","ENSG00000148248.13",0.54]
["CYB561","ENSG00000008283.15",0.53]
["CHGB","ENSG00000089199.9",0.5]
["DBH","ENSG00000123454.10",0.5]
["GCH1","ENSG00000131979.18",0.48]
["PHOX2B","ENSG00000109132.6",0.48]
["TBX20","ENSG00000164532.10",0.48]
["SLC6A2","ENSG00000103546.18",0.47]
["RP11-269G24.4","ENSG00000265282.1",0.47]
["HACD3","ENSG00000074696.12",0.47]
["LINC00682","ENSG00000245870.2",0.46]
["ATP6V1G1","ENSG00000136888.6",0.46]
["UBQLN1","ENSG00000135018.13",0.46]
["CHGA","ENSG00000100604.12",0.46]
["CHRNA3","ENSG00000080644.15",0.45]
["HTATSF1","ENSG00000102241.11",0.45]
["TH","ENSG00000180176.14",0.45]
["RBM18","ENSG00000119446.13",0.45]
["RP11-415I12.2","ENSG00000255583.2",0.45]
["COG5","ENSG00000164597.13",0.45]
["KCNG4","ENSG00000168418.7",0.44]
["YIPF6","ENSG00000181704.11",0.44]
["YIPF5","ENSG00000145817.16",0.44]
["C18orf42","ENSG00000231824.3",0.44]
["DDC","ENSG00000132437.17",0.44]
["ERLEC1","ENSG00000068912.13",0.44]
["DNAJC3","ENSG00000102580.14",0.44]
["DRD2","ENSG00000149295.13",0.44]
["INIP","ENSG00000148153.13",0.43]
["SEZ6L2","ENSG00000174938.14",0.43]
["TM9SF2","ENSG00000125304.8",0.43]
["ALG2","ENSG00000119523.9",0.43]
["G3BP2","ENSG00000138757.14",0.43]
["SLC18A1","ENSG00000036565.14",0.43]
["NIPA2","ENSG00000140157.14",0.43]
["MAB21L1","ENSG00000180660.7",0.43]
["IER3IP1","ENSG00000134049.4",0.42]
["SAR1B","ENSG00000152700.13",0.42]
["RP11-662M24.2","ENSG00000256725.1",0.42]
["PROKR1","ENSG00000169618.6",0.42]
["GPR107","ENSG00000148358.19",0.42]
["DGKK","ENSG00000274588.1",0.42]
["RP11-561B11.6","ENSG00000259017.1",0.42]
["RP11-481F24.3","ENSG00000278928.1",0.42]
["RP11-124O11.1","ENSG00000234944.1",0.42]
["JKAMP","ENSG00000050130.17",0.42]
["CFAP20","ENSG00000070761.7",0.42]
["TNPO1","ENSG00000083312.17",0.41]
["MRAP2","ENSG00000135324.5",0.41]
["TMEM33","ENSG00000109133.12",0.41]
["PRPF4","ENSG00000136875.12",0.41]
["TLX2","ENSG00000115297.10",0.41]
["PDE12","ENSG00000174840.8",0.41]
["RP11-227F19.1","ENSG00000250467.1",0.41]
["ATP6AP1","ENSG00000071553.16",0.41]
["DOLPP1","ENSG00000167130.17",0.41]
["UMAD1","ENSG00000219545.9",0.41]
["SCG2","ENSG00000171951.4",0.41]
["TMED7","ENSG00000134970.13",0.41]
["DOLK","ENSG00000175283.7",0.4]
["COPB2","ENSG00000184432.9",0.4]
["ARL1","ENSG00000120805.13",0.4]
["ERP44","ENSG00000023318.7",0.4]
["SLC18A2","ENSG00000165646.11",0.4]
["VPS33A","ENSG00000139719.9",0.4]
["ARFGEF3","ENSG00000112379.8",0.4]
["YME1L1","ENSG00000136758.18",0.4]
["TOR1B","ENSG00000136816.15",0.4]
["NDUFS1","ENSG00000023228.13",0.4]
["MRPL50","ENSG00000136897.7",0.4]
["MBTPS2","ENSG00000012174.11",0.4]
["SEC24A","ENSG00000113615.12",0.4]
["SLC39A9","ENSG00000029364.11",0.4]
["CHUK","ENSG00000213341.10",0.4]
["RAD23B","ENSG00000119318.12",0.4]
["ITFG1","ENSG00000129636.12",0.4]
["PSMD5","ENSG00000095261.13",0.4]
["SLC30A9","ENSG00000014824.13",0.39]
["PRRC1","ENSG00000164244.20",0.39]
["PHOX2A","ENSG00000165462.5",0.39]
["EML5","ENSG00000165521.15",0.39]
["ATP7A","ENSG00000165240.17",0.39]
["ASAH2B","ENSG00000204147.9",0.39]
["PSMC2","ENSG00000161057.10",0.39]
["PGGT1B","ENSG00000164219.9",0.39]
["SEC23B","ENSG00000101310.14",0.39]
["GORASP2","ENSG00000115806.12",0.39]
["ACBD3","ENSG00000182827.8",0.39]
["TMED2","ENSG00000086598.10",0.39]
["FAM120A","ENSG00000048828.16",0.39]
["TOR1A","ENSG00000136827.11",0.39]
["SMIM15","ENSG00000188725.7",0.39]
["DSTNP5","ENSG00000236681.1",0.39]
["KDELR2","ENSG00000136240.9",0.39]
["SYT4","ENSG00000132872.11",0.39]
["RNF20","ENSG00000155827.11",0.38]
["L1CAM","ENSG00000198910.12",0.38]
["HLCS","ENSG00000159267.14",0.38]
["TM9SF3","ENSG00000077147.14",0.38]
["MRPL19","ENSG00000115364.13",0.38]

{"sheet":"Stable4","index":3,"n_rows":31,"n_cols":4,"rows_kept":31,"merged":[[0,0,0,9]],"flags":["formulas_cached_only"]}
["Supplementary Table 4.GO cellular component (CC) enrichment analysis of 100 SLC31A1-correlated genes."]
["Term ","Count","PValue","Genes"]
["GO:0005789~endoplasmic reticulum membrane",22,{"v":1.85e-09,"d":"1.85E-09"},"COPB2, SEC24A, ATP6AP1, SAR1B, YIPF5, SURF4, ALG2, DOLK, SEZ6L2, HACD3, IER3IP1, ERP44, GORASP2, TMEM33, JKAMP, DOLPP1, TMED2, KDELR2, TMED7, MRAP2, SLC18A1, SEC23B"]
["GO:0005783~endoplasmic reticulum",22,{"v":8.95e-09,"d":"8.95E-09"},"SLC30A9, TOR1A, SAR1B, YIPF5, SURF4, DOLK, DBH, SEZ6L2, HACD3, IER3IP1, TOR1B, DNAJC3, ERLEC1, TMEM33, YIPF6, UBQLN1, TMED2, KDELR2, TMED7, ATP7A, MRAP2, SEC23B"]
["GO:0030134~ER to Golgi transport vesicle",5,{"v":3.34e-05,"d":"3.34E-05"},"YIPF5, YIPF6, TMED2, IER3IP1, TMED7"]
["GO:0030127~COPII vesicle coat",4,{"v":3.52e-05,"d":"3.52E-05"},"SEC24A, SAR1B, TMED7, SEC23B"]
["GO:0030133~transport vesicle",6,{"v":6.64e-05,"d":"6.64E-05"},"CHGA, COPB2, SURF4, TMED2, KDELR2, TMED7"]
["GO:0000139~Golgi membrane",12,{"v":8.55e-05,"d":"8.55E-05"},"COPB2, COG5, GORASP2, SURF4, ARL1, YIPF6, TMED2, KDELR2, DRD2, TMED7, ACBD3, MBTPS2"]
["GO:0030663~COPI-coated vesicle membrane",3,{"v":0.00039,"d":"3.90E-04"},"COPB2, TMED2, KDELR2"]
["GO:0070971~endoplasmic reticulum exit site",4,{"v":0.000436,"d":"4.36E-04"},"SEC24A, SAR1B, YIPF5, SEC23B"]
["GO:0098992~neuronal dense core vesicle",3,{"v":0.000665,"d":"6.65E-04"},"CHGA, SYT4, SCG2"]
["GO:0030141~secretory granule",5,{"v":0.000829,"d":"8.29E-04"},"CHGA, TOR1A, ATP7A, SCG2, CHGB"]
["GO:0012507~ER to Golgi transport vesicle membrane",4,0.001884184,"SEC24A, SAR1B, TMED2, SEC23B"]
["GO:0000502~proteasome complex",4,0.001982631,"PSMD5, PSMC2, UBQLN1, RAD23B"]
["GO:0005788~endoplasmic reticulum lumen",7,0.002260835,"DNAJC3, ERLEC1, ERP44, TOR1A, TOR1B, SCG2, CHGB"]
["GO:0016020~membrane",22,0.002336927,"SYT4, TOR1A, ATP6AP1, COG5, ALG2, NIPA2, DBH, IER3IP1, SLC6A2, TM9SF3, DNAJC3, TM9SF2, GORASP2, PSMC2, FAM120A, UBQLN1, YME1L1, NDUFS1, GPR107, ACBD3, ATP7A, SLC18A2"]
["GO:0005794~Golgi apparatus",13,0.002618872,"COG5, SAR1B, YIPF5, ARL1, IER3IP1, TM9SF2, PRRC1, GORASP2, TMED2, GPR107, TMED7, ACBD3, ATP7A"]
["GO:0016021~integral component of membrane",37,0.002711594,"CHRNA3, KCNG4, DBH, SEZ6L2, HACD3, IER3IP1, SLC6A2, TM9SF3, SLC39A9, TMED2, TMED7, DRD2, ATP7A, SLC18A1, ARFGEF3, SLC30A9, SMIM15, ATP6AP1, VPS33A, YIPF5, SURF4, ALG2, DOLK, NIPA2, L1CAM, ITFG1, TM9SF2, TMEM33, JKAMP, DOLPP1, YIPF6, YME1L1, KDELR2, GPR107, MRAP2, CYB561, MBTPS2"]
["GO:0033116~endoplasmic reticulum-Golgi intermediate compartment membrane",4,0.004826796,"ATP6AP1, SURF4, TMED2, TMED7"]
["GO:0005793~endoplasmic reticulum-Golgi intermediate compartment",4,0.005180336,"ERP44, SURF4, TMED2, TMED7"]
["GO:0030176~integral component of endoplasmic reticulum membrane",4,0.018922892,"TMEM33, DOLPP1, DOLK, HACD3"]
["GO:0030424~axon",6,0.019000722,"SYT4, DDC, TH, DRD2, L1CAM, ATP7A"]
["GO:0008021~synaptic vesicle",4,0.021311631,"DDC, TOR1A, TH, SLC18A2"]
["GO:0070083~clathrin-sculpted monoamine transport vesicle membrane",2,0.021634624,"SLC18A1, SLC18A2"]
["GO:0043195~terminal bouton",3,0.024901239,"TH, SLC18A1, SLC18A2"]
["GO:0043025~neuronal cell body",6,0.030207052,"SYT4, CHRNA3, DDC, SEZ6L2, L1CAM, ATP7A"]
["GO:0042584~chromaffin granule membrane",2,0.038608597,"DBH, CYB561"]
["GO:0048471~perinuclear region of cytoplasm",8,0.046607624,"CHGA, SYT4, TH, VPS33A, ALG2, UBQLN1, ATP7A, SEC23B"]
["GO:0030672~synaptic vesicle membrane",3,0.047790597,"DRD2, SLC18A1, SLC18A2"]
["GO:0005802~trans-Golgi network",4,0.049214563,"YIPF5, ARL1, YIPF6, ATP7A"]
["GO:0030425~dendrite",6,0.04971128,"SYT4, CHRNA3, TH, DRD2, L1CAM, ATP7A"]

{"sheet":"Stable5","index":4,"n_rows":39,"n_cols":4,"rows_kept":39,"merged":[[0,0,0,3]],"flags":["formulas_cached_only"]}
["Supplementary Table 5.GO biological process (BP) enrichment analysis of 100 SLC31A1-correlated genes."]
["Term","Count","PValue","Genes"]
["GO:0006888~ER to Golgi vesicle-mediated transport",9,{"v":5.86e-08,"d":"5.86E-08"},"COPB2, SEC24A, SAR1B, YIPF5, TMED2, KDELR2, IER3IP1, TMED7, SEC23B"]
["GO:0006886~intracellular protein transport",8,{"v":0.000426,"d":"4.26E-04"},"COPB2, SEC24A, SAR1B, VPS33A, ARL1, TMED2, TMED7, SEC23B"]
["GO:0015031~protein transport",8,0.002642389,"COG5, VPS33A, YIPF5, TMED2, KDELR2, IER3IP1, TMED7, SEC23B"]
["GO:0016192~vesicle-mediated transport",7,{"v":0.000305,"d":"3.05E-04"},"COPB2, SYT4, SAR1B, VPS33A, YIPF5, ARL1, SEC23B"]
["GO:0007626~locomotory behavior",6,{"v":3.19e-05,"d":"3.19E-05"},"CHRNA3, TH, DBH, DRD2, ATP7A, SLC18A2"]
["GO:0007030~Golgi organization",6,{"v":0.000199,"d":"1.99E-04"},"COG5, GORASP2, SURF4, ARL1, TMED2, TMED7"]
["GO:0034976~response to endoplasmic reticulum stress",5,{"v":0.000423,"d":"4.23E-04"},"ERP44, GORASP2, TMEM33, UBQLN1, MBTPS2"]
["GO:0015842~aminergic neurotransmitter loading into synaptic vesicle",4,{"v":3.01e-07,"d":"3.01E-07"},"DDC, TH, SLC18A1, SLC18A2"]
["GO:0001975~response to amphetamine",4,{"v":0.000666,"d":"6.66E-04"},"TH, DBH, DRD2, SLC18A2"]
["GO:0006986~response to unfolded protein",4,0.001689233,"DNAJC3, ERP44, JKAMP, TOR1B"]
["GO:0015844~monoamine transport",3,{"v":0.000498,"d":"4.98E-04"},"SLC6A2, SLC18A1, SLC18A2"]
["GO:0042416~dopamine biosynthetic process",3,{"v":0.000797,"d":"7.97E-04"},"DDC, GCH1, TH"]
["GO:0006996~organelle organization",3,0.001369185,"CHGA, TOR1A, GORASP2"]
["GO:0048484~enteric nervous system development",3,0.00183292,"TLX2, PHOX2B, PHOX2A"]
["GO:0048265~response to pain",3,0.002088957,"GCH1, DBH, SLC6A2"]
["GO:0043473~pigmentation",3,0.004699193,"TH, DRD2, ATP7A"]
["GO:0006836~neurotransmitter transport",3,0.013948583,"SLC6A2, SLC18A1, SLC18A2"]
["GO:0006879~cellular iron ion homeostasis",3,0.024812264,"ATP6V1G1, ATP6AP1, CYB561"]
["GO:0030433~ubiquitin-dependent ERAD pathway",3,0.047177292,"ERLEC1, JKAMP, UBQLN1"]
["GO:0052314~phytoalexin metabolic process",2,0.00854274,"DDC, TH"]
["GO:0033604~negative regulation of catecholamine secretion",2,0.00854274,"CHGA, SYT4"]
["GO:0033076~isoquinoline alkaloid metabolic process",2,0.012787036,"DDC, TH"]
["GO:0032368~regulation of lipid transport",2,0.017013384,"SAR1B, SURF4"]
["GO:0046684~response to pyrethroid",2,0.017013384,"DDC, TH"]
["GO:1903912~negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation",2,0.021221858,"DNAJC3, TMED2"]
["GO:0051584~regulation of dopamine uptake involved in synaptic transmission",2,0.021221858,"TOR1A, DRD2"]
["GO:0006489~dolichyl diphosphate biosynthetic process",2,0.025412533,"DOLPP1, DOLK"]
["GO:0071763~nuclear membrane organization",2,0.029585483,"TOR1A, TOR1B"]
["GO:0051610~serotonin uptake",2,0.029585483,"SLC18A1, SLC18A2"]
["GO:0003357~noradrenergic neuron differentiation",2,0.029585483,"PHOX2B, PHOX2A"]
["GO:1990384~hyaloid vascular plexus regression",2,0.029585483,"TH, DRD2"]
["GO:0042421~norepinephrine biosynthetic process",2,0.029585483,"TH, DBH"]
["GO:0048149~behavioral response to ethanol",2,0.033740783,"DBH, DRD2"]
["GO:0006584~catecholamine metabolic process",2,0.033740783,"DDC, ATP7A"]
["GO:0071312~cellular response to alkaloid",2,0.033740783,"DDC, TH"]
["GO:0036295~cellular response to increased oxygen levels",2,0.033740783,"ATP6V1G1, ATP6AP1"]
["GO:0001963~synaptic transmission, dopaminergic",2,0.046101515,"TH, DRD2"]

{"sheet":"Stable6","index":5,"n_rows":8,"n_cols":4,"rows_kept":8,"merged":[[0,0,0,3]],"flags":["formulas_cached_only"]}
["Supplementary Table 6.GO molecular function (MF) enrichment analysis of 100 SLC31A1-correlated genes."]
["Term","Count","PValue","Genes"]
["GO:0008504~monoamine transmembrane transporter activity",3,{"v":0.000649630274403474,"d":"6.50E-04"},"SLC6A2, SLC18A1, SLC18A2"]
["GO:0005335~serotonin:sodium symporter activity",2,0.0128945071989006,"SLC18A1, SLC18A2"]
["GO:0035240~dopamine binding",2,0.0298320540944299,"TH, DRD2"]
["GO:0016887~ATPase activity",5,0.0540156422092242,"ATP6V1G1, TOR1A, PSMC2, YME1L1, TOR1B"]
["GO:0016597~amino acid binding",2,0.0789412367371363,"DDC, TH"]
["GO:0005515~protein binding",61,0.0963167156761127,"UMAD1, DBH, IER3IP1, SLC6A2, SLC39A9, PSMD5, TMED2, TNPO1, ATP7A, SLC18A2, CHGB, ATP6V1G1, ATP6AP1, CHUK, COG5, VPS33A, ALG2, RAD23B, INIP, PRPF4, GORASP2, TMEM33, YME1L1, NDUFS1, SCG2, COPB2, DDC, CHRNA3, SAR1B, MRPL19, ARL1, HACD3, ERLEC1, PRRC1, HLCS, UBQLN1, G3BP2, PGGT1B, DRD2, CFAP20, SEC23B, RNF20, SYT4, SEC24A, TOR1A, GCH1, YIPF5, SURF4, DOLK, L1CAM, TOR1B, PHOX2A, ERP44, TH, TLX2, MAB21L1, PSMC2, YIPF6, ACBD3, MRAP2, CYB561"]

{"sheet":"Stable7","index":6,"n_rows":15,"n_cols":4,"rows_kept":15,"merged":[[0,0,0,3]],"flags":["formulas_cached_only"]}
["Supplementary Table 7.KEGG enrichment analysis of 100 SLC31A1-correlated genes."]
["Term","Count","PValue","Genes"]
["hsa04141:Protein processing in endoplasmic reticulum",8,{"v":9.65e-06,"d":"9.65E-06"},"DNAJC3, ERLEC1, SEC24A, SAR1B, UBQLN1, SEC23B, RAD23B, MBTPS2"]
["hsa05030:Cocaine addiction",5,{"v":6.61e-05,"d":"6.61E-05"},"DDC, TH, DRD2, SLC18A1, SLC18A2"]
["hsa05012:Parkinson disease",7,0.001138741,"TH, SLC39A9, PSMC2, NDUFS1, DRD2, SLC18A1, SLC18A2"]
["hsa04728:Dopaminergic synapse",5,0.002880315,"DDC, TH, DRD2, SLC18A1, SLC18A2"]
["hsa05031:Amphetamine addiction",4,0.003683118,"DDC, TH, SLC18A1, SLC18A2"]
["hsa04721:Synaptic vesicle cycle",4,0.005200189,"ATP6V1G1, SLC6A2, SLC18A1, SLC18A2"]
["hsa05034:Alcoholism",5,0.009847731,"DDC, TH, DRD2, SLC18A1, SLC18A2"]
["hsa00350:Tyrosine metabolism",3,0.011487834,"DDC, TH, DBH"]
["hsa05110:Vibrio cholerae infection",3,0.021467135,"ATP6V1G1, ATP6AP1, KDELR2"]
["hsa00510:N-Glycan biosynthesis",3,0.021467135,"DOLPP1, ALG2, DOLK"]
["hsa01100:Metabolic pathways",13,0.035025296,"DDC, ATP6V1G1, GCH1, ATP6AP1, ALG2, DOLK, DBH, HACD3, TH, HLCS, DOLPP1, NDUFS1, DGKK"]
["hsa05120:Epithelial cell signaling in Helicobacter pylori infection",3,0.039996246,"ATP6V1G1, ATP6AP1, CHUK"]
["hsa04726:Serotonergic synapse",3,0.095720379,"DDC, SLC18A1, SLC18A2"]